# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- RNA_pol_Rpb1_5 PF04998.17 AFZ64212.1 - 5.6e-53 180.1 0.3 9.5e-51 172.8 0.3 2.6 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_4 PF05000.17 AFZ64212.1 - 5e-12 45.7 0.2 4.1e-11 42.8 0.1 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_3 PF04983.18 AFZ64212.1 - 7.7e-05 22.7 0.9 0.00037 20.5 0.0 2.7 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 Arg_repressor PF01316.21 AFZ64212.1 - 0.024 14.4 0.0 0.19 11.5 0.0 2.5 2 0 0 2 2 2 0 Arginine repressor, DNA binding domain RNA_pol_Rpb2_6 PF00562.28 AFZ64213.1 - 1.5e-131 439.0 0.0 4.5e-131 437.5 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_2 PF04561.14 AFZ64213.1 - 4.9e-25 88.3 1.9 1.5e-23 83.4 1.9 2.2 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 AFZ64213.1 - 7.8e-24 83.9 0.0 1.5e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 AFZ64213.1 - 1.3e-23 82.9 0.0 2.8e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_1 PF04563.15 AFZ64213.1 - 2.1e-09 37.2 0.0 9.1e-09 35.1 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_45 PF10385.9 AFZ64213.1 - 9.4e-05 22.6 0.0 0.0003 21.0 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase beta subunit external 1 domain Peptidase_M23 PF01551.22 AFZ64213.1 - 0.11 12.7 0.5 0.97 9.7 0.1 2.8 3 0 0 3 3 3 0 Peptidase family M23 SecA_DEAD PF07517.14 AFZ64214.1 - 1.2e-103 346.4 0.2 1.8e-103 345.8 0.2 1.2 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_PP_bind PF01043.20 AFZ64214.1 - 4.4e-29 101.4 0.0 1.6e-28 99.6 0.0 2.1 1 0 0 1 1 1 1 SecA preprotein cross-linking domain SecA_SW PF07516.13 AFZ64214.1 - 6.1e-18 65.6 4.2 6.3e-18 65.6 2.2 2.1 2 0 0 2 2 2 1 SecA Wing and Scaffold domain DEAD PF00270.29 AFZ64214.1 - 0.00021 21.1 0.6 0.00059 19.6 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 AFZ64214.1 - 0.19 12.1 0.0 0.19 12.1 0.0 2.8 3 0 0 3 3 3 0 Helicase conserved C-terminal domain RNA_pol_Rpb1_1 PF04997.12 AFZ64215.1 - 6.6e-55 186.6 2.0 3.7e-54 184.2 0.3 2.7 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 AFZ64215.1 - 1.2e-32 113.5 0.0 5.5e-30 104.8 0.0 2.8 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 AFZ64215.1 - 3.7e-11 43.2 0.3 3.2e-10 40.2 0.2 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 DUF1882 PF08966.11 AFZ64215.1 - 0.052 13.8 0.9 0.78 10.0 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1882) PsaA_PsaB PF00223.19 AFZ64216.1 - 0 1244.7 38.8 0 1244.5 38.8 1.0 1 0 0 1 1 1 1 Photosystem I psaA/psaB protein PsaA_PsaB PF00223.19 AFZ64217.1 - 0 1109.7 39.3 0 1109.5 39.3 1.0 1 0 0 1 1 1 1 Photosystem I psaA/psaB protein Peptidase_M41 PF01434.18 AFZ64218.1 - 2.5e-51 174.3 0.2 2.5e-51 174.3 0.2 1.6 2 0 0 2 2 1 1 Peptidase family M41 AAA PF00004.29 AFZ64218.1 - 2.9e-45 153.9 0.3 1e-44 152.2 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AFZ64218.1 - 4.6e-13 48.7 0.0 1.2e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 AFZ64218.1 - 1.6e-06 28.1 0.3 0.00015 21.8 0.1 3.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AFZ64218.1 - 3.5e-06 27.5 0.4 0.00069 20.0 0.1 3.7 3 1 0 3 3 3 1 AAA ATPase domain FtsH_ext PF06480.15 AFZ64218.1 - 1.6e-05 25.2 1.2 9.8e-05 22.7 0.1 2.8 3 0 0 3 3 3 1 FtsH Extracellular RuvB_N PF05496.12 AFZ64218.1 - 7.8e-05 22.5 0.0 0.00045 20.0 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 AFZ64218.1 - 0.00024 21.3 0.0 0.0011 19.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 AFZ64218.1 - 0.00028 20.2 0.1 0.00028 20.2 0.1 1.7 2 0 0 2 2 1 1 TIP49 P-loop domain AAA_22 PF13401.6 AFZ64218.1 - 0.0013 19.0 0.0 0.22 11.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 AFZ64218.1 - 0.0064 15.8 0.2 0.31 10.3 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin IstB_IS21 PF01695.17 AFZ64218.1 - 0.007 16.1 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 AFZ64218.1 - 0.0088 16.1 0.0 0.043 13.8 0.0 2.2 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 AFZ64218.1 - 0.0099 15.3 0.0 0.024 14.0 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 AFZ64218.1 - 0.05 13.3 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain ATPase PF06745.13 AFZ64218.1 - 0.054 12.8 1.1 0.49 9.7 0.0 2.9 3 0 0 3 3 3 0 KaiC AAA_18 PF13238.6 AFZ64218.1 - 0.06 13.9 1.4 0.22 12.1 0.1 2.5 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 AFZ64218.1 - 0.063 13.2 0.0 0.33 10.8 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 AFZ64218.1 - 0.068 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 AFZ64218.1 - 0.068 13.2 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 AFZ64218.1 - 0.08 12.4 0.1 0.44 10.0 0.1 2.3 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 AFZ64218.1 - 0.084 13.0 0.0 0.36 11.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AFZ64218.1 - 0.1 12.3 0.3 1.2 8.8 0.1 2.7 3 1 0 3 3 3 0 AAA domain Ninjurin PF04923.12 AFZ64218.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Ninjurin AAA_11 PF13086.6 AFZ64218.1 - 0.13 12.1 1.9 1.6 8.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 AFZ64218.1 - 0.18 12.2 1.5 1.5 9.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain HSP70 PF00012.20 AFZ64219.1 - 4.2e-234 778.2 13.5 4.7e-234 778.1 13.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 AFZ64219.1 - 2.8e-23 82.2 2.8 1.8e-19 69.7 0.1 3.4 3 1 0 3 3 3 2 MreB/Mbl protein FtsA PF14450.6 AFZ64219.1 - 0.00028 21.2 2.3 0.012 16.0 0.0 3.0 3 1 0 3 3 3 1 Cell division protein FtsA Actin PF00022.19 AFZ64219.1 - 0.0023 16.6 0.2 0.23 10.0 0.1 2.3 2 0 0 2 2 2 2 Actin StbA PF06406.11 AFZ64219.1 - 0.0075 15.5 0.0 0.0075 15.5 0.0 2.3 3 0 0 3 3 3 1 StbA protein FGGY_C PF02782.16 AFZ64219.1 - 0.029 14.1 0.0 0.33 10.6 0.0 2.3 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 AFZ64219.1 - 0.084 12.1 0.6 0.39 9.9 0.1 2.2 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase PRCC PF10253.9 AFZ64219.1 - 0.26 12.0 4.6 0.55 11.0 4.6 1.6 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting LemA PF04011.12 AFZ64219.1 - 4.3 7.2 9.6 2.3 8.1 6.6 2.1 2 0 0 2 2 2 0 LemA family PSII PF00421.19 AFZ64220.1 - 5.4e-255 846.8 8.3 6.1e-255 846.7 8.3 1.0 1 0 0 1 1 1 1 Photosystem II protein Oxidored_nitro PF00148.19 AFZ64221.1 - 8.5e-73 245.4 0.0 1e-72 245.1 0.0 1.0 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase PCP_red PF08369.10 AFZ64221.1 - 1.8e-14 53.6 0.1 4.5e-14 52.4 0.0 1.7 2 0 0 2 2 2 1 Proto-chlorophyllide reductase 57 kD subunit Gag_p10 PF02337.17 AFZ64221.1 - 0.13 12.2 0.1 2.7 8.0 0.0 2.4 2 0 0 2 2 2 0 Retroviral GAG p10 protein ATP-synt_ab PF00006.25 AFZ64222.1 - 5.2e-73 245.2 0.3 7.3e-73 244.7 0.3 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 AFZ64222.1 - 1.3e-44 151.5 1.3 2e-44 150.9 1.3 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 AFZ64222.1 - 4.5e-09 36.7 5.6 1e-08 35.5 5.6 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 AFZ64222.1 - 8.2e-06 25.3 0.1 1.8e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 KaiC AAA PF00004.29 AFZ64223.1 - 2.6e-27 95.9 0.2 9.5e-27 94.0 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 AFZ64223.1 - 1.7e-07 31.0 0.0 3.5e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 AFZ64223.1 - 8.7e-05 22.8 0.3 1.4 9.2 0.0 4.0 3 1 1 4 4 4 2 AAA domain NACHT PF05729.12 AFZ64223.1 - 0.0036 17.2 1.4 0.49 10.3 0.2 2.5 1 1 1 2 2 2 2 NACHT domain DUF815 PF05673.13 AFZ64223.1 - 0.0055 15.9 0.1 0.038 13.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 AFZ64223.1 - 0.034 14.2 0.5 0.53 10.3 0.4 2.9 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AFZ64223.1 - 0.046 14.1 0.1 0.34 11.3 0.1 2.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 AFZ64223.1 - 0.09 12.9 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain UPF0051 PF01458.17 AFZ64224.1 - 7e-64 215.5 0.3 8.9e-64 215.2 0.3 1.1 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) TPP_enzyme_M PF00205.22 AFZ64225.1 - 4.8e-51 172.1 0.0 7.6e-51 171.4 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 AFZ64225.1 - 6.8e-49 165.6 0.0 3.4e-48 163.3 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.18 AFZ64225.1 - 1.7e-18 66.8 0.0 5.3e-18 65.2 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain ATP-synt_ab PF00006.25 AFZ64226.1 - 4.1e-62 209.6 0.1 6.5e-62 209.0 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 AFZ64226.1 - 8.7e-12 45.4 0.2 2.1e-11 44.1 0.2 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain T3SS_ATPase_C PF18269.1 AFZ64226.1 - 0.00081 19.2 0.6 0.0055 16.5 0.6 2.3 1 1 0 1 1 1 1 T3SS EscN ATPase C-terminal domain ATPase PF06745.13 AFZ64226.1 - 0.0014 18.1 0.2 0.0028 17.0 0.1 1.6 2 0 0 2 2 2 1 KaiC RsgA_GTPase PF03193.16 AFZ64226.1 - 0.0043 17.0 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 AFZ64226.1 - 0.016 15.7 0.0 1.5 9.3 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 AFZ64226.1 - 0.027 15.0 0.0 0.21 12.1 0.0 2.2 2 0 0 2 2 2 0 ABC transporter ATPase_2 PF01637.18 AFZ64226.1 - 0.056 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 AFZ64226.1 - 0.067 13.5 1.3 0.57 10.5 0.3 2.4 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 AFZ64226.1 - 0.19 12.2 0.0 0.51 10.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 AFZ64226.1 - 0.2 10.8 0.4 0.39 9.9 0.1 1.6 2 0 0 2 2 2 0 NB-ARC domain RuBisCO_large PF00016.20 AFZ64227.1 - 3.4e-127 423.7 0.0 4.2e-127 423.5 0.0 1.1 1 0 0 1 1 1 1 Ribulose bisphosphate carboxylase large chain, catalytic domain RuBisCO_large_N PF02788.16 AFZ64227.1 - 3.8e-44 149.7 0.0 9.4e-44 148.4 0.0 1.7 1 0 0 1 1 1 1 Ribulose bisphosphate carboxylase large chain, N-terminal domain PSII PF00421.19 AFZ64228.1 - 1.1e-145 486.2 13.8 1.4e-145 485.8 13.8 1.1 1 0 0 1 1 1 1 Photosystem II protein Cpn60_TCP1 PF00118.24 AFZ64229.1 - 1.2e-32 113.3 0.0 3.5e-32 111.7 0.0 1.7 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family AAA_2 PF07724.14 AFZ64230.1 - 5.7e-53 179.5 0.0 9.9e-53 178.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.9 AFZ64230.1 - 1.6e-16 60.1 0.0 4.2e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 AFZ64230.1 - 2e-13 50.5 0.0 4.5e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 AFZ64230.1 - 2.4e-09 37.7 0.0 2.8e-08 34.3 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Torsin PF06309.11 AFZ64230.1 - 1.4e-05 25.2 0.0 3.1e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Torsin Sigma54_activat PF00158.26 AFZ64230.1 - 1.6e-05 24.7 0.0 3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.6 AFZ64230.1 - 2.2e-05 24.8 2.6 0.00091 19.5 0.2 3.5 2 1 1 3 3 2 1 AAA domain AAA_7 PF12775.7 AFZ64230.1 - 0.0002 21.0 0.0 0.0022 17.6 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 AFZ64230.1 - 0.00053 20.2 0.0 0.033 14.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 AFZ64230.1 - 0.001 19.6 0.0 0.0022 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 AFZ64230.1 - 0.0011 19.0 0.0 0.0038 17.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 AFZ64230.1 - 0.005 17.2 1.5 0.041 14.3 0.0 2.8 3 0 0 3 3 2 1 RNA helicase AAA_16 PF13191.6 AFZ64230.1 - 0.0082 16.5 0.1 0.044 14.2 0.0 2.2 1 1 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 AFZ64230.1 - 0.017 14.2 0.0 0.034 13.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DEAD PF00270.29 AFZ64230.1 - 0.023 14.5 0.0 7.2 6.3 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase RuvB_N PF05496.12 AFZ64230.1 - 0.031 14.0 0.0 0.17 11.6 0.0 2.0 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 AFZ64230.1 - 0.035 14.1 0.0 0.09 12.8 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 AFZ64230.1 - 0.038 13.3 0.0 0.076 12.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.17 AFZ64230.1 - 0.049 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Roc PF08477.13 AFZ64230.1 - 0.061 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_6 PF12774.7 AFZ64230.1 - 0.064 12.2 0.0 0.15 11.0 0.0 1.6 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region DNA_pol3_delta2 PF13177.6 AFZ64230.1 - 0.099 12.4 0.0 5.8 6.7 0.0 2.4 2 0 0 2 2 2 0 DNA polymerase III, delta subunit AAA_3 PF07726.11 AFZ64230.1 - 0.1 12.5 0.0 6.2 6.7 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 AFZ64230.1 - 0.11 12.4 0.0 0.35 10.7 0.0 1.8 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea RNA_pol_L PF01193.24 AFZ64231.1 - 3e-07 29.8 0.4 9.4e-07 28.2 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_A_bac PF01000.26 AFZ64231.1 - 3.7e-05 24.1 0.1 0.00013 22.3 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain Oxidored_nitro PF00148.19 AFZ64232.1 - 3.1e-44 151.3 0.0 3.6e-44 151.1 0.0 1.0 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase ResB PF05140.14 AFZ64233.1 - 1.1e-49 169.5 0.2 7.6e-40 137.1 0.3 2.1 1 1 0 2 2 2 2 ResB-like family AAA_lid_2 PF17863.1 AFZ64234.1 - 4.8e-18 64.8 0.7 8e-18 64.1 0.7 1.4 1 0 0 1 1 1 1 AAA lid domain Mg_chelatase PF01078.21 AFZ64234.1 - 5.8e-10 38.9 0.0 2.1e-06 27.3 0.0 2.5 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 AFZ64234.1 - 8.7e-08 32.3 0.0 0.00057 19.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) MCM PF00493.23 AFZ64234.1 - 1.3e-06 27.7 0.0 0.0047 16.0 0.0 2.3 2 0 0 2 2 2 2 MCM P-loop domain AAA_22 PF13401.6 AFZ64234.1 - 6.5e-06 26.5 0.1 0.00023 21.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 AFZ64234.1 - 9.4e-05 22.9 0.0 0.00023 21.6 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 AFZ64234.1 - 0.00037 20.2 0.0 0.0007 19.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Sigma54_activat PF00158.26 AFZ64234.1 - 0.00077 19.2 0.0 0.22 11.2 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA PF00004.29 AFZ64234.1 - 0.0079 16.6 0.0 0.12 12.9 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 AFZ64234.1 - 0.0083 15.3 0.0 0.026 13.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 AFZ64234.1 - 0.016 14.8 0.0 0.035 13.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 AFZ64234.1 - 0.032 14.7 0.0 0.18 12.3 0.0 2.0 2 0 0 2 2 2 0 ABC transporter TniB PF05621.11 AFZ64234.1 - 0.062 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_18 PF13238.6 AFZ64234.1 - 0.077 13.5 0.0 0.91 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 AFZ64234.1 - 0.1 12.3 0.1 0.57 9.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 AFZ64234.1 - 0.17 12.2 0.5 1.4 9.2 0.5 2.3 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 AFZ64234.1 - 0.18 11.5 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 AFZ64235.1 - 8e-59 198.5 0.2 1.1e-58 198.0 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 AFZ64235.1 - 1.5e-32 112.2 0.6 2.9e-32 111.3 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 AFZ64235.1 - 7.7e-19 67.9 6.3 1.6e-18 66.8 6.3 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 AFZ64235.1 - 2.5e-05 24.3 0.1 5.8e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 AFZ64235.1 - 0.0093 15.9 0.0 0.04 13.8 0.0 1.9 1 1 1 2 2 2 1 RsgA GTPase cobW PF02492.19 AFZ64235.1 - 0.025 14.2 0.6 0.048 13.3 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SecY PF00344.20 AFZ64236.1 - 1.9e-34 119.4 11.4 2.4e-34 119.0 11.4 1.0 1 0 0 1 1 1 1 SecY translocase AAA_lid_9 PF17871.1 AFZ64237.1 - 5e-29 100.3 0.2 1.5e-28 98.8 0.0 1.8 1 1 1 2 2 2 1 AAA lid domain AAA PF00004.29 AFZ64237.1 - 3.4e-15 56.6 0.0 8.2e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 AFZ64237.1 - 8.7e-09 35.0 0.0 3e-06 26.8 0.0 2.8 2 1 0 2 2 2 1 Bacterial TniB protein AAA_16 PF13191.6 AFZ64237.1 - 3.9e-08 33.9 0.5 8.2e-07 29.6 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 AFZ64237.1 - 9.6e-08 32.4 0.1 8.8e-05 22.8 0.0 3.3 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 AFZ64237.1 - 4.4e-05 23.5 0.0 0.00054 20.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 AFZ64237.1 - 0.00031 20.7 0.0 0.00073 19.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 AFZ64237.1 - 0.0008 19.4 0.3 0.0042 17.0 0.1 2.2 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 AFZ64237.1 - 0.0014 18.4 0.0 0.0029 17.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 AFZ64237.1 - 0.0049 16.9 0.0 0.016 15.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain Sigma54_activat PF00158.26 AFZ64237.1 - 0.021 14.5 0.0 0.058 13.1 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain NTPase_1 PF03266.15 AFZ64237.1 - 0.033 14.1 0.1 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.22 AFZ64237.1 - 0.037 14.4 0.0 0.23 11.9 0.0 2.1 2 0 0 2 2 2 0 RNA helicase RuvB_N PF05496.12 AFZ64237.1 - 0.043 13.6 1.1 3.2 7.5 0.8 2.7 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 AFZ64237.1 - 0.064 12.8 0.1 0.24 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 AFZ64237.1 - 0.074 12.8 0.0 0.16 11.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 AFZ64237.1 - 0.093 11.9 0.0 0.57 9.3 0.0 2.0 2 0 0 2 2 2 0 TIP49 P-loop domain Roc PF08477.13 AFZ64237.1 - 0.094 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 AFZ64237.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 AFZ64237.1 - 0.19 12.1 0.3 0.45 10.8 0.2 1.9 1 1 0 1 1 1 0 AAA domain Photo_RC PF00124.19 AFZ64238.1 - 2.3e-93 312.2 14.2 2.8e-93 311.9 14.2 1.0 1 0 0 1 1 1 1 Photosynthetic reaction centre protein Photo_RC PF00124.19 AFZ64239.1 - 1.4e-74 250.6 16.9 1.7e-74 250.4 16.9 1.0 1 0 0 1 1 1 1 Photosynthetic reaction centre protein Rubrerythrin PF02915.17 AFZ64240.1 - 1.3e-40 139.0 0.0 2.8e-40 137.9 0.0 1.6 1 0 0 1 1 1 1 Rubrerythrin rve_3 PF13683.6 AFZ64240.1 - 0.0058 16.4 0.4 0.016 14.9 0.1 1.8 2 0 0 2 2 2 1 Integrase core domain FA_desaturase_2 PF03405.14 AFZ64240.1 - 0.18 10.6 0.0 3.9 6.2 0.0 2.2 2 0 0 2 2 2 0 Fatty acid desaturase AAA PF00004.29 AFZ64241.1 - 5.2e-13 49.6 0.0 1.2e-12 48.4 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 AFZ64241.1 - 2.7e-09 37.1 0.0 1.6e-08 34.6 0.0 2.2 2 0 0 2 2 2 1 AAA lid domain AAA_22 PF13401.6 AFZ64241.1 - 3.9e-06 27.2 0.0 0.035 14.4 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_33 PF13671.6 AFZ64241.1 - 0.00034 20.8 0.0 0.00054 20.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 AFZ64241.1 - 0.00076 18.9 0.1 0.0062 15.9 0.1 2.0 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 AFZ64241.1 - 0.0016 18.4 0.0 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 NTPase KTI12 PF08433.10 AFZ64241.1 - 0.003 17.1 0.0 0.0055 16.2 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_5 PF07728.14 AFZ64241.1 - 0.004 17.2 0.0 0.0097 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 AFZ64241.1 - 0.0044 17.6 0.0 0.0094 16.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 AFZ64241.1 - 0.005 15.9 0.2 0.012 14.6 0.1 1.7 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2075 PF09848.9 AFZ64241.1 - 0.01 15.1 0.1 0.53 9.5 0.1 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.6 AFZ64241.1 - 0.01 16.3 0.1 0.029 14.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 AFZ64241.1 - 0.013 15.8 0.1 0.086 13.2 0.0 2.3 2 1 1 3 3 3 0 RNA helicase AAA_30 PF13604.6 AFZ64241.1 - 0.014 15.1 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 AFZ64241.1 - 0.019 15.1 0.0 0.045 13.9 0.0 1.7 1 0 0 1 1 1 0 Torsin AAA_16 PF13191.6 AFZ64241.1 - 0.029 14.7 0.0 0.052 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 AFZ64241.1 - 0.038 14.2 0.0 0.072 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 AFZ64241.1 - 0.043 13.1 0.0 0.089 12.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_2 PF07724.14 AFZ64241.1 - 0.071 13.2 0.1 0.16 12.1 0.0 1.6 2 0 0 2 2 1 0 AAA domain (Cdc48 subfamily) ResIII PF04851.15 AFZ64241.1 - 0.081 12.9 0.0 0.26 11.3 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Zot PF05707.12 AFZ64241.1 - 0.088 12.4 0.1 1.2 8.7 0.0 2.3 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) AAA_19 PF13245.6 AFZ64241.1 - 0.089 13.1 0.0 0.27 11.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 AFZ64241.1 - 0.092 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase RuvB_N PF05496.12 AFZ64241.1 - 0.15 11.8 0.1 0.48 10.1 0.1 2.0 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Apocytochr_F_N PF16639.5 AFZ64242.1 - 1e-73 246.7 0.1 1.6e-73 246.1 0.1 1.3 1 0 0 1 1 1 1 Apocytochrome F, N-terminal Apocytochr_F_C PF01333.19 AFZ64242.1 - 1.2e-45 154.4 2.4 1.9e-45 153.7 2.4 1.3 1 0 0 1 1 1 1 Apocytochrome F, C-terminal Cytochrom_C_asm PF01578.20 AFZ64243.1 - 3.6e-64 216.4 19.7 3.6e-64 216.4 19.7 2.2 2 1 0 2 2 2 1 Cytochrome C assembly protein Fer4_NifH PF00142.18 AFZ64244.1 - 4.4e-106 354.3 0.0 5e-106 354.1 0.0 1.0 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CbiA PF01656.23 AFZ64244.1 - 2.6e-14 53.4 0.0 6.6e-14 52.1 0.0 1.6 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 AFZ64244.1 - 8e-14 51.9 0.1 2.3e-10 40.7 0.0 2.8 3 0 0 3 3 3 2 AAA domain ArsA_ATPase PF02374.15 AFZ64244.1 - 1.5e-08 34.2 0.2 1.5e-08 34.2 0.2 1.6 2 0 0 2 2 2 1 Anion-transporting ATPase ParA PF10609.9 AFZ64244.1 - 2.8e-06 27.0 0.0 8.8e-06 25.4 0.0 1.8 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase MipZ PF09140.11 AFZ64244.1 - 7.7e-05 22.1 0.1 0.00019 20.8 0.1 1.6 1 0 0 1 1 1 1 ATPase MipZ MeaB PF03308.16 AFZ64244.1 - 0.0048 15.9 0.4 0.0097 14.9 0.0 1.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_26 PF13500.6 AFZ64244.1 - 0.015 15.1 0.0 0.075 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 AFZ64244.1 - 0.019 14.7 0.0 0.033 13.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 AFZ64244.1 - 0.027 14.0 0.0 0.059 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 AFZ64244.1 - 0.16 11.9 0.1 0.4 10.6 0.1 1.7 1 0 0 1 1 1 0 NACHT domain DUF87 PF01935.17 AFZ64244.1 - 0.3 11.2 1.7 2.1 8.4 0.2 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain ABC_tran PF00005.27 AFZ64245.1 - 1.9e-16 60.8 0.0 3.2e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 AFZ64245.1 - 4.9e-05 23.3 2.0 0.24 11.2 0.1 2.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 AFZ64245.1 - 0.00016 21.2 1.4 0.26 10.7 0.3 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 AFZ64245.1 - 0.0032 17.2 1.3 0.0054 16.4 0.3 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 AFZ64245.1 - 0.005 17.1 0.1 0.45 10.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.6 AFZ64245.1 - 0.0085 14.8 0.0 0.012 14.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 AFZ64245.1 - 0.0098 15.8 0.1 0.018 15.0 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase Cytidylate_kin PF02224.18 AFZ64245.1 - 0.016 15.0 0.0 0.046 13.4 0.0 1.8 2 0 0 2 2 2 0 Cytidylate kinase AAA_33 PF13671.6 AFZ64245.1 - 0.018 15.2 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 AFZ64245.1 - 0.022 15.3 1.2 0.14 12.8 0.3 2.3 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 AFZ64245.1 - 0.031 14.8 0.2 0.031 14.8 0.2 1.9 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 AFZ64245.1 - 0.053 13.8 0.0 0.23 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 AFZ64245.1 - 0.07 13.6 0.1 1.6 9.2 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 AFZ64245.1 - 0.11 12.5 0.0 5.8 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 AFZ64245.1 - 0.16 12.3 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 AFZ64245.1 - 0.21 11.1 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Ribosomal_L2_C PF03947.18 AFZ64246.1 - 4.3e-56 188.5 0.2 8.1e-56 187.6 0.2 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 AFZ64246.1 - 3.2e-33 113.5 2.8 7.9e-33 112.3 2.6 1.8 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain ThiG PF05690.14 AFZ64247.1 - 1.3e-91 306.4 0.0 1.4e-91 306.2 0.0 1.0 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 AFZ64247.1 - 9.4e-08 31.8 0.2 2.6e-07 30.3 0.1 1.6 2 0 0 2 2 2 1 Histidine biosynthesis protein Dus PF01207.17 AFZ64247.1 - 1.9e-05 23.9 0.0 2.9e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) FMN_dh PF01070.18 AFZ64247.1 - 0.0001 21.5 0.1 0.00017 20.7 0.1 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 AFZ64247.1 - 0.0002 20.5 0.5 0.00027 20.1 0.5 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NanE PF04131.14 AFZ64247.1 - 0.0011 18.2 0.2 0.0035 16.6 0.1 1.9 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.21 AFZ64247.1 - 0.091 11.9 0.1 0.14 11.3 0.1 1.2 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase Ribosomal_L4 PF00573.22 AFZ64248.1 - 8.6e-38 130.0 0.1 1.2e-37 129.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family TatC PF00902.18 AFZ64249.1 - 9.2e-38 130.1 20.2 1.2e-37 129.7 20.2 1.2 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) Ribosomal_S2 PF00318.20 AFZ64250.1 - 1.6e-75 253.0 0.0 2e-75 252.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S2 ATP-synt_A PF00119.20 AFZ64251.1 - 2.9e-51 174.4 12.1 3.6e-51 174.1 12.1 1.1 1 0 0 1 1 1 1 ATP synthase A chain Ribosomal_L1 PF00687.21 AFZ64252.1 - 3e-49 167.5 0.1 4e-49 167.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Cytochrome_B PF00033.19 AFZ64253.1 - 1.2e-84 282.9 13.8 1.3e-84 282.7 13.8 1.0 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 AFZ64253.1 - 1.7e-38 132.3 6.2 1.7e-38 132.3 6.2 1.4 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Ni_hydr_CYTB PF01292.20 AFZ64253.1 - 4.3e-06 26.5 4.2 4.3e-06 26.5 4.2 2.1 1 1 1 2 2 2 2 Prokaryotic cytochrome b561 DUF4405 PF14358.6 AFZ64253.1 - 4.3e-05 24.0 4.6 4.3e-05 24.0 4.6 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4405) DUF373 PF04123.13 AFZ64253.1 - 0.56 9.6 3.4 0.7 9.3 3.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Ribosomal_S4 PF00163.19 AFZ64254.1 - 9.9e-21 74.5 8.2 1.8e-20 73.6 8.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 AFZ64254.1 - 1.4e-17 63.1 0.0 4e-17 61.6 0.0 1.9 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 AFZ64254.1 - 0.02 14.7 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 S4 domain Ribosomal_L3 PF00297.22 AFZ64255.1 - 4e-14 52.4 1.8 7e-13 48.3 0.2 2.5 1 1 2 3 3 3 2 Ribosomal protein L3 YGGT PF02325.17 AFZ64257.1 - 9.1e-06 26.0 0.3 3.1e-05 24.3 0.3 1.9 1 0 0 1 1 1 1 YGGT family Ycf4 PF02392.16 AFZ64258.1 - 7.5e-21 74.5 0.1 9.7e-21 74.1 0.1 1.0 1 0 0 1 1 1 1 Ycf4 PSI_PsaF PF02507.15 AFZ64259.1 - 4.8e-75 251.2 0.0 5.6e-75 250.9 0.0 1.0 1 0 0 1 1 1 1 Photosystem I reaction centre subunit III Ribosomal_L5_C PF00673.21 AFZ64260.1 - 8.2e-36 122.1 0.0 1.4e-35 121.3 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 AFZ64260.1 - 1.2e-17 63.9 0.5 2.2e-17 63.1 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 DUF2862 PF11061.8 AFZ64260.1 - 0.021 14.7 0.1 0.068 13.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2862) Ribosomal_L6 PF00347.23 AFZ64261.1 - 3.5e-31 107.7 2.9 3.5e-17 62.8 0.4 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Legionella_OMP PF05150.12 AFZ64261.1 - 0.047 12.6 0.0 0.059 12.3 0.0 1.2 1 0 0 1 1 1 0 Legionella pneumophila major outer membrane protein precursor Ribosomal_S5_C PF03719.15 AFZ64262.1 - 1.3e-24 85.4 1.3 2.3e-24 84.6 1.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 AFZ64262.1 - 4.3e-21 74.7 4.0 7.2e-21 74.0 4.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain PsaL PF02605.15 AFZ64263.1 - 6.6e-46 155.7 0.5 8.2e-46 155.4 0.5 1.1 1 0 0 1 1 1 1 Photosystem I reaction centre subunit XI Transgly_assoc PF04226.13 AFZ64263.1 - 0.2 12.0 7.2 2.1 8.7 0.5 2.5 2 0 0 2 2 2 0 Transglycosylase associated protein DUF4538 PF15061.6 AFZ64263.1 - 7.4 6.4 7.5 0.45 10.3 1.6 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4538) DUF1230 PF06799.11 AFZ64264.1 - 5.3e-36 123.9 1.7 6.4e-36 123.6 1.7 1.1 1 0 0 1 1 1 1 Conserved in the green lineage and diatoms 27 TPR_1 PF00515.28 AFZ64265.1 - 5.8e-20 70.2 16.6 1.3e-08 34.3 1.2 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 AFZ64265.1 - 3.9e-15 54.7 14.2 1.5e-06 27.8 0.4 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 AFZ64265.1 - 6.1e-10 38.5 15.6 8.9e-05 22.4 1.0 4.5 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 AFZ64265.1 - 2.9e-09 37.1 8.8 0.00019 21.7 1.0 3.6 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 AFZ64265.1 - 2.8e-07 30.1 8.8 0.001 18.9 0.1 4.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 AFZ64265.1 - 3.4e-07 30.2 8.3 0.0041 17.4 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 AFZ64265.1 - 1.1e-06 29.0 0.7 0.25 12.2 0.0 3.7 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 AFZ64265.1 - 1.2e-06 28.2 13.0 0.0042 16.9 0.8 4.9 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 AFZ64265.1 - 3.8e-06 27.4 0.5 0.00087 19.9 0.4 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 AFZ64265.1 - 4e-06 26.4 21.4 0.0034 17.0 3.7 3.8 2 1 1 3 3 3 2 TPR repeat EST1_DNA_bind PF10373.9 AFZ64265.1 - 0.00036 20.1 2.7 0.0008 19.0 2.4 1.8 1 1 1 2 2 2 1 Est1 DNA/RNA binding domain TPR_6 PF13174.6 AFZ64265.1 - 0.00046 20.6 6.8 0.17 12.6 0.1 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.18 AFZ64265.1 - 0.00073 19.5 16.7 0.3 11.2 0.2 4.0 3 1 1 4 4 4 2 MIT (microtubule interacting and transport) domain TPR_9 PF13371.6 AFZ64265.1 - 0.0014 18.8 0.1 0.5 10.6 0.2 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 AFZ64265.1 - 0.009 16.5 4.0 0.012 16.1 1.7 2.3 2 1 0 2 2 2 1 Tetratricopeptide repeat DUF3808 PF10300.9 AFZ64265.1 - 0.013 14.3 2.8 0.016 14.0 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) Fis1_TPR_C PF14853.6 AFZ64265.1 - 0.03 14.4 2.3 0.03 14.4 2.3 2.8 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat DUF2225 PF09986.9 AFZ64265.1 - 0.045 13.5 8.6 0.51 10.0 2.6 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Arm-DNA-bind_5 PF17293.2 AFZ64265.1 - 0.071 13.6 1.9 0.17 12.4 1.9 1.6 1 0 0 1 1 1 0 Arm DNA-binding domain HemY_N PF07219.13 AFZ64265.1 - 0.085 13.1 0.4 0.44 10.8 0.0 2.2 1 1 1 2 2 2 0 HemY protein N-terminus ANAPC3 PF12895.7 AFZ64265.1 - 0.095 12.9 7.4 1.9 8.8 1.6 2.6 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 PaREP1 PF05942.11 AFZ64265.1 - 0.15 12.0 4.5 0.21 11.5 1.0 2.1 1 1 1 2 2 2 0 Archaeal PaREP1/PaREP8 family Cytochrom_C550 PF14495.6 AFZ64266.1 - 9.3e-59 197.0 0.0 1.1e-58 196.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c-550 domain Cytochrom_C PF00034.21 AFZ64266.1 - 2.5e-05 25.4 0.0 3.3e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 AFZ64266.1 - 5.7e-05 23.4 0.0 0.00024 21.4 0.0 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III ATP-synt_B PF00430.18 AFZ64267.1 - 5.9e-11 42.6 7.9 2.1e-10 40.8 7.8 1.8 1 1 0 1 1 1 1 ATP synthase B/B' CF(0) Nic96 PF04097.14 AFZ64267.1 - 0.00021 19.9 1.8 0.00026 19.6 1.8 1.2 1 0 0 1 1 1 1 Nup93/Nic96 DUF2634 PF10934.8 AFZ64267.1 - 0.0022 18.1 2.5 0.0033 17.5 2.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2634) zf-C4H2 PF10146.9 AFZ64267.1 - 0.021 15.1 2.5 0.027 14.8 2.5 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein DUF1844 PF08899.11 AFZ64267.1 - 0.065 13.5 0.2 0.11 12.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1844) DUF948 PF06103.11 AFZ64267.1 - 0.094 13.0 0.9 0.16 12.2 0.4 1.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) NADHdeh_related PF10125.9 AFZ64267.1 - 0.14 11.5 0.1 0.25 10.7 0.1 1.4 1 0 0 1 1 1 0 NADH dehydrogenase I, subunit N related protein DUF2481 PF10654.9 AFZ64267.1 - 0.2 11.6 3.5 0.27 11.2 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2481) Fib_alpha PF08702.10 AFZ64267.1 - 0.39 10.9 6.7 0.52 10.5 6.7 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family SWI-SNF_Ssr4 PF08549.10 AFZ64267.1 - 0.42 9.2 4.4 0.47 9.0 4.4 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Cytochrom_B_C PF00032.17 AFZ64268.1 - 5.7e-18 65.1 0.3 9.5e-18 64.4 0.3 1.3 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Ribosomal_S7 PF00177.21 AFZ64269.1 - 3e-52 176.2 0.9 3.4e-52 176.1 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e TMP-TENI PF02581.17 AFZ64269.1 - 0.11 11.8 0.0 0.35 10.2 0.0 1.7 2 0 0 2 2 2 0 Thiamine monophosphate synthase Ribosomal_L22 PF00237.19 AFZ64270.1 - 7.5e-30 103.2 0.4 1.1e-29 102.7 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_L21p PF00829.21 AFZ64271.1 - 8.7e-14 51.6 0.0 2.3e-11 43.8 0.0 2.2 1 1 0 1 1 1 1 Ribosomal prokaryotic L21 protein Ribosomal_L13 PF00572.18 AFZ64272.1 - 3e-45 153.5 0.1 3.4e-45 153.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 S-l_SbsC_C PF18316.1 AFZ64272.1 - 0.05 14.1 1.2 0.51 10.9 1.3 2.1 2 0 0 2 2 2 0 S-layer protein SbsC C-terminal domain Cation_ATPase_N PF00690.26 AFZ64272.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus DUF2490 PF10677.9 AFZ64272.1 - 0.14 12.1 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2490) Ribosomal_L11_N PF03946.14 AFZ64273.1 - 6.1e-32 109.3 0.7 3.1e-30 103.8 0.1 2.3 2 0 0 2 2 2 2 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 AFZ64273.1 - 1.9e-22 79.5 1.2 3.2e-22 78.8 1.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain ATP-synt_DE_N PF02823.16 AFZ64274.1 - 3.1e-20 71.9 0.1 4e-20 71.5 0.1 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ATP-synt_DE PF00401.20 AFZ64274.1 - 0.00032 20.9 1.1 0.0005 20.3 1.1 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, long alpha-helix domain COG5 PF10392.9 AFZ64274.1 - 0.0047 17.1 0.2 0.0077 16.4 0.2 1.3 1 0 0 1 1 1 1 Golgi transport complex subunit 5 LXG PF04740.12 AFZ64274.1 - 0.0058 16.4 1.8 0.0075 16.0 1.8 1.1 1 0 0 1 1 1 1 LXG domain of WXG superfamily SMP_2 PF10144.9 AFZ64274.1 - 0.033 13.8 0.6 0.054 13.1 0.4 1.5 1 1 0 1 1 1 0 Bacterial virulence factor haemolysin HetR_C PF18460.1 AFZ64274.1 - 0.073 13.0 0.3 0.24 11.4 0.3 1.8 2 0 0 2 2 2 0 Heterocyst differentiation regulator C-terminal Hood domain Ribosomal_L16 PF00252.18 AFZ64275.1 - 1e-46 158.2 0.7 1.1e-46 158.1 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e PsaD PF02531.16 AFZ64276.1 - 1.8e-58 195.9 0.0 2e-58 195.7 0.0 1.0 1 0 0 1 1 1 1 PsaD Ribosomal_S9 PF00380.19 AFZ64277.1 - 1.6e-38 131.9 0.3 1.8e-38 131.7 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Glyoxalase_5 PF14696.6 AFZ64277.1 - 0.093 12.9 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal HU-CCDC81_bac_2 PF18175.1 AFZ64277.1 - 0.14 12.0 0.1 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 2 Ribosomal_L20 PF00453.18 AFZ64278.1 - 2.8e-41 139.9 3.9 3.5e-41 139.6 3.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L20 Thump_like PF18096.1 AFZ64278.1 - 0.019 14.9 0.2 0.029 14.3 0.2 1.4 1 0 0 1 1 1 0 THUMP domain-like Ribosomal_S8 PF00410.19 AFZ64279.1 - 5e-42 142.8 0.2 5.6e-42 142.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_L12 PF00542.19 AFZ64280.1 - 7e-28 96.8 12.1 5.2e-27 94.0 5.8 2.4 2 1 1 3 3 3 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 AFZ64280.1 - 1.1e-14 53.8 1.8 1.1e-14 53.8 1.8 3.7 4 0 0 4 4 4 2 Ribosomal protein L7/L12 dimerisation domain DUF2551 PF10826.8 AFZ64280.1 - 0.049 13.9 0.2 0.21 11.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2551) NRD1_2 PF01995.16 AFZ64280.1 - 0.062 12.6 0.3 0.1 11.9 0.0 1.4 2 0 0 2 2 2 0 NrpR regulatory domains NRD1 and 2 DUF4375 PF14300.6 AFZ64280.1 - 0.14 12.4 0.2 3.3 8.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) Ribosomal_S11 PF00411.19 AFZ64281.1 - 1.3e-38 131.7 1.1 1.5e-38 131.5 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 ELFV_dehydrog PF00208.21 AFZ64281.1 - 0.0053 16.5 0.7 0.022 14.5 0.4 1.8 1 1 1 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Ribosomal_L18p PF00861.22 AFZ64281.1 - 0.031 14.6 0.0 0.041 14.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast DUF5643 PF18705.1 AFZ64281.1 - 0.15 12.0 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5643) Ribosom_S12_S23 PF00164.25 AFZ64282.1 - 2.6e-40 136.6 1.6 3.2e-40 136.3 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 REPA_OB_2 PF16900.5 AFZ64282.1 - 0.17 11.8 0.0 0.55 10.2 0.0 1.7 1 1 1 2 2 2 0 Replication protein A OB domain Ribosomal_S13 PF00416.22 AFZ64283.1 - 9.4e-32 110.1 3.1 2.7e-30 105.4 3.1 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 AFZ64283.1 - 0.0017 17.2 0.0 0.0018 17.1 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) H2TH PF06831.14 AFZ64283.1 - 0.016 15.2 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Formamidopyrimidine-DNA glycosylase H2TH domain DUF4640 PF15480.6 AFZ64283.1 - 0.02 14.6 0.2 0.021 14.6 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4640) Ribosomal_L19 PF01245.20 AFZ64284.1 - 4.6e-31 107.0 1.0 5.4e-31 106.8 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L19 Ribosomal_L14 PF00238.19 AFZ64285.1 - 7.8e-51 171.3 1.4 8.6e-51 171.1 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Cytochrome_CBB3 PF13442.6 AFZ64286.1 - 5.7e-17 61.8 0.0 7.1e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 AFZ64286.1 - 9.8e-09 35.0 0.1 2.5e-06 27.3 0.0 2.1 1 1 1 2 2 2 2 Cytochrome c-550 domain Cytochrom_C PF00034.21 AFZ64286.1 - 3.2e-08 34.6 0.3 2.7e-07 31.6 0.3 2.0 1 1 0 1 1 1 1 Cytochrome c Ribosomal_L23 PF00276.20 AFZ64287.1 - 1.2e-21 76.8 0.1 1.6e-21 76.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L23 CAF20 PF17052.5 AFZ64288.1 - 0.026 14.7 0.9 0.034 14.3 0.9 1.1 1 0 0 1 1 1 0 Cap associated factor Glyco_hydro_42C PF08533.10 AFZ64288.1 - 0.11 12.2 0.2 0.29 10.9 0.1 1.7 1 1 0 1 1 1 0 Beta-galactosidase C-terminal domain Ribosomal_S10 PF00338.22 AFZ64289.1 - 6.4e-19 68.0 0.0 1.1e-18 67.3 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S10p/S20e Ribosomal_L27 PF01016.19 AFZ64290.1 - 5.4e-34 116.1 3.7 6.9e-34 115.7 3.7 1.1 1 0 0 1 1 1 1 Ribosomal L27 protein Ycf54 PF10674.9 AFZ64291.1 - 5e-29 100.4 0.5 5.7e-29 100.2 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2488) Ribosomal_S6 PF01250.17 AFZ64292.1 - 6.1e-09 36.0 0.0 7e-09 35.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S6 Ribosomal_L18p PF00861.22 AFZ64293.1 - 2.8e-35 121.2 0.0 3e-35 121.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Fer2 PF00111.27 AFZ64294.1 - 8e-20 70.6 0.5 1.1e-19 70.2 0.5 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Zn_Tnp_IS91 PF14319.6 AFZ64294.1 - 0.059 13.4 0.0 0.08 13.0 0.0 1.4 1 1 0 1 1 1 0 Transposase zinc-binding domain Ycf66_N PF07444.11 AFZ64295.1 - 9.3e-27 93.0 4.1 1.1e-26 92.7 4.1 1.1 1 0 0 1 1 1 1 Ycf66 protein N-terminus Ribosomal_S14 PF00253.21 AFZ64296.1 - 5.6e-24 83.7 0.3 1.1e-23 82.8 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4391 PF14335.6 AFZ64296.1 - 0.0036 17.0 2.6 0.0044 16.8 2.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4391) DUF2499 PF10693.9 AFZ64297.1 - 6e-22 77.7 5.8 6.8e-22 77.6 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2499) YmcE_antitoxin PF15939.5 AFZ64297.1 - 0.088 13.0 2.3 4.4 7.5 0.7 2.1 1 1 1 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system DUF3810 PF12725.7 AFZ64297.1 - 1.7 7.9 5.2 2 7.7 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Orai-1 PF07856.12 AFZ64297.1 - 2 8.1 8.8 3.6 7.3 7.8 1.6 1 1 1 2 2 2 0 Mediator of CRAC channel activity DUF3624 PF12292.8 AFZ64297.1 - 5 7.6 10.6 4.6 7.7 6.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3624) Ribosomal_S20p PF01649.18 AFZ64298.1 - 1.7e-25 89.4 12.9 2e-25 89.2 12.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S20 Ribosomal_S19 PF00203.21 AFZ64299.1 - 3.3e-31 107.0 0.3 3.9e-31 106.8 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 RuBisCO_small PF00101.20 AFZ64300.1 - 1.4e-12 47.4 0.0 2.9e-12 46.4 0.0 1.5 2 0 0 2 2 2 1 Ribulose bisphosphate carboxylase, small chain Ribosomal_S3_C PF00189.20 AFZ64301.1 - 4.9e-26 91.1 0.1 7e-26 90.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain Ribosomal_S17 PF00366.20 AFZ64302.1 - 1.1e-28 99.1 2.0 1.2e-28 99.0 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_S16 PF00886.19 AFZ64303.1 - 2.7e-18 65.8 0.1 3.4e-18 65.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 ATP-synt_C PF00137.21 AFZ64304.1 - 3.2e-20 72.2 6.9 4e-20 71.9 6.9 1.1 1 0 0 1 1 1 1 ATP synthase subunit C Cytochrom_B559a PF00284.20 AFZ64305.1 - 2.3e-23 81.6 0.7 3e-23 81.3 0.7 1.2 1 0 0 1 1 1 1 Lumenal portion of Cytochrome b559, alpha (gene psbE) subunit Cytochrom_B559 PF00283.19 AFZ64305.1 - 1.1e-16 59.9 1.5 1.6e-16 59.4 1.5 1.3 1 0 0 1 1 1 1 Cytochrome b559, alpha (gene psbE) and beta (gene psbF)subunits Fer4 PF00037.27 AFZ64306.1 - 9.4e-15 53.7 11.7 2.5e-07 30.2 2.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.7 AFZ64306.1 - 1.5e-10 40.7 12.6 6.8e-06 25.9 2.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 AFZ64306.1 - 7.1e-10 39.3 14.7 1.2e-09 38.6 14.7 1.3 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 AFZ64306.1 - 2.3e-09 37.2 26.7 1.4e-06 28.3 17.1 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 AFZ64306.1 - 4.6e-09 36.3 13.6 8.8e-09 35.4 13.6 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 AFZ64306.1 - 6.6e-09 35.6 18.2 9e-05 22.7 2.8 2.5 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 AFZ64306.1 - 1.4e-08 35.2 9.8 0.00045 20.7 2.2 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 AFZ64306.1 - 1.6e-08 35.4 10.1 0.00088 20.2 3.3 2.1 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 AFZ64306.1 - 2.6e-08 33.9 15.0 5.2e-08 32.9 15.1 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 AFZ64306.1 - 1.6e-07 30.9 17.3 0.00064 19.7 3.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_3 PF12798.7 AFZ64306.1 - 1.2e-05 25.9 17.6 0.0028 18.5 5.1 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_22 PF17179.4 AFZ64306.1 - 1.9e-05 25.4 10.4 0.0031 18.3 1.5 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 AFZ64306.1 - 0.00013 22.4 12.3 0.0034 17.9 2.5 2.2 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_8 PF13183.6 AFZ64306.1 - 0.00046 20.6 16.0 0.023 15.1 3.2 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.6 AFZ64306.1 - 0.0067 16.6 13.3 0.23 11.7 3.4 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.6 AFZ64306.1 - 0.013 16.2 10.4 0.019 15.7 1.6 2.2 2 0 0 2 2 2 0 4Fe-4S single cluster domain ETF_QO PF05187.13 AFZ64306.1 - 0.016 15.3 3.6 0.023 14.8 3.6 1.3 1 1 0 1 1 1 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S ThiS PF02597.20 AFZ64307.1 - 0.00014 22.4 0.0 0.00021 21.9 0.0 1.3 1 1 0 1 1 1 1 ThiS family Ribosomal_L31 PF01197.18 AFZ64308.1 - 9.8e-24 83.4 0.2 1.2e-23 83.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L31 Ribosomal_S18 PF01084.20 AFZ64309.1 - 1.6e-17 63.4 0.3 1.9e-17 63.2 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S18 Ribosomal_L29 PF00831.23 AFZ64310.1 - 1.8e-07 31.0 1.2 2.2e-07 30.7 1.2 1.2 1 0 0 1 1 1 1 Ribosomal L29 protein PsbH PF00737.20 AFZ64311.1 - 3.6e-29 100.2 1.6 4.5e-29 99.9 1.6 1.1 1 0 0 1 1 1 1 Photosystem II 10 kDa phosphoprotein Ac81 PF05820.11 AFZ64311.1 - 0.13 11.9 0.4 0.15 11.6 0.4 1.1 1 0 0 1 1 1 0 Baculoviridae AC81 PSI_PsaE PF02427.17 AFZ64312.1 - 2.5e-32 110.4 1.9 2.8e-32 110.2 1.9 1.0 1 0 0 1 1 1 1 Photosystem I reaction centre subunit IV / PsaE Ribosomal_L33 PF00471.20 AFZ64313.1 - 1.2e-21 76.9 8.0 1.4e-21 76.7 8.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 RNA_POL_M_15KD PF02150.16 AFZ64313.1 - 0.0033 17.3 0.6 0.17 11.8 0.1 2.2 2 0 0 2 2 2 2 RNA polymerases M/15 Kd subunit DZR PF12773.7 AFZ64313.1 - 0.062 13.3 2.6 0.11 12.5 2.8 1.4 1 1 0 1 1 1 0 Double zinc ribbon NOB1_Zn_bind PF08772.11 AFZ64313.1 - 0.087 13.0 6.7 0.48 10.6 6.7 2.0 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Zn-ribbon_8 PF09723.10 AFZ64313.1 - 0.11 12.6 3.4 1.1 9.4 3.4 2.0 1 1 0 1 1 1 0 Zinc ribbon domain Ribosomal_L35p PF01632.19 AFZ64314.1 - 2.9e-13 50.1 12.4 3.1e-13 50.0 12.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L35 DUF1819 PF08849.11 AFZ64314.1 - 0.0021 17.9 0.3 0.0027 17.6 0.3 1.1 1 0 0 1 1 1 1 Putative inner membrane protein (DUF1819) Ycf9 PF01737.17 AFZ64315.1 - 1.5e-10 40.7 2.3 1.7e-10 40.6 2.3 1.0 1 0 0 1 1 1 1 YCF9 RSN1_TM PF13967.6 AFZ64315.1 - 0.042 13.6 0.1 0.042 13.6 0.1 1.2 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport LMBR1 PF04791.16 AFZ64315.1 - 0.27 10.1 4.6 0.28 10.0 4.6 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein SLATT_5 PF18160.1 AFZ64315.1 - 1.4 8.2 3.4 1.5 8.1 3.4 1.0 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Ribosomal_L32p PF01783.23 AFZ64317.1 - 1.3e-05 25.3 6.0 1.7e-05 24.9 6.0 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family PsbN PF02468.15 AFZ64318.1 - 1e-18 66.9 0.1 1.2e-18 66.6 0.1 1.1 1 0 0 1 1 1 1 Photosystem II reaction centre N protein (psbN) Ribosomal_L34 PF00468.17 AFZ64319.1 - 4.7e-14 52.1 12.4 5.2e-14 51.9 12.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L34 PSI_PsaJ PF01701.18 AFZ64320.1 - 2.1e-23 82.5 0.8 2.5e-23 82.3 0.8 1.1 1 0 0 1 1 1 1 Photosystem I reaction centre subunit IX / PsaJ PsbK PF02533.15 AFZ64321.1 - 3.2e-23 81.6 9.4 3.5e-23 81.4 9.4 1.0 1 0 0 1 1 1 1 Photosystem II 4 kDa reaction centre component Cytochrom_B559 PF00283.19 AFZ64322.1 - 1.2e-17 63.0 2.5 1.5e-17 62.7 2.5 1.2 1 0 0 1 1 1 1 Cytochrome b559, alpha (gene psbE) and beta (gene psbF)subunits Oleosin PF01277.17 AFZ64322.1 - 0.075 12.8 0.3 0.079 12.7 0.3 1.0 1 0 0 1 1 1 0 Oleosin PsbJ PF01788.17 AFZ64323.1 - 8.1e-21 73.6 9.2 8.6e-21 73.5 9.2 1.0 1 0 0 1 1 1 1 PsbJ PsbX PF06596.11 AFZ64324.1 - 6.5e-17 61.3 3.1 6.8e-17 61.2 3.1 1.0 1 0 0 1 1 1 1 Photosystem II reaction centre X protein (PsbX) PsbI PF02532.14 AFZ64325.1 - 1.3e-19 69.9 1.2 1.3e-19 69.8 1.2 1.0 1 0 0 1 1 1 1 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Ribosomal_L36 PF00444.18 AFZ64326.1 - 2.3e-16 59.7 13.3 2.5e-16 59.6 13.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L36 PsbY PF06298.11 AFZ64327.1 - 1.7e-14 53.4 1.2 1.8e-14 53.4 1.2 1.0 1 0 0 1 1 1 1 Photosystem II protein Y (PsbY) Tad PF13400.6 AFZ64327.1 - 0.015 15.6 0.2 0.016 15.5 0.2 1.1 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like PetG PF02529.15 AFZ64328.1 - 4.8e-21 74.3 2.9 5e-21 74.3 2.9 1.0 1 0 0 1 1 1 1 Cytochrome B6-F complex subunit 5 PGF-CTERM PF18204.1 AFZ64328.1 - 0.0081 16.1 2.2 0.12 12.4 0.4 2.1 1 1 1 2 2 2 2 PGF-CTERM motif COX14 PF14880.6 AFZ64328.1 - 0.033 14.0 0.7 0.037 13.9 0.7 1.1 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Collectrin PF16959.5 AFZ64328.1 - 0.047 13.5 0.2 0.051 13.3 0.2 1.0 1 0 0 1 1 1 0 Renal amino acid transporter Comm PF15957.5 AFZ64328.1 - 0.14 12.5 0.1 0.14 12.5 0.1 1.0 1 0 0 1 1 1 0 Commissureless PsbT PF01405.17 AFZ64329.1 - 7.3e-18 64.1 7.2 8e-18 63.9 7.2 1.0 1 0 0 1 1 1 1 Photosystem II reaction centre T protein YlaH PF14036.6 AFZ64329.1 - 0.0076 16.6 0.8 0.0076 16.6 0.8 1.0 1 0 0 1 1 1 1 YlaH-like protein PetN PF03742.14 AFZ64330.1 - 1.5e-14 53.5 9.6 1.6e-14 53.4 9.6 1.0 1 0 0 1 1 1 1 PetN DUF4094 PF13334.6 AFZ64330.1 - 0.2 12.1 0.7 0.23 11.9 0.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Proton_antipo_M PF00361.20 AFZ64331.1 - 2.3e-82 276.5 20.9 2.3e-82 276.5 20.9 2.8 3 0 0 3 3 3 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 AFZ64331.1 - 2.7e-22 78.6 8.5 1.6e-21 76.1 5.6 3.2 2 0 0 2 2 2 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus NADH5_C PF06455.11 AFZ64331.1 - 1.3e-12 47.7 12.3 1.3e-12 47.7 12.3 4.5 3 2 0 3 3 3 1 NADH dehydrogenase subunit 5 C-terminus Proton_antipo_C PF01010.19 AFZ64331.1 - 0.00014 21.6 1.8 0.00014 21.6 1.8 2.0 2 0 0 2 2 2 1 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus Proton_antipo_M PF00361.20 AFZ64332.1 - 4.1e-73 246.1 29.9 4.1e-73 246.1 29.9 2.4 1 1 1 2 2 2 1 Proton-conducting membrane transporter MLANA PF14991.6 AFZ64332.1 - 0.45 10.8 1.0 0.84 9.9 0.1 2.0 2 0 0 2 2 2 0 Protein melan-A DUF2897 PF11446.8 AFZ64332.1 - 1.3 9.0 3.3 1.9 8.4 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2897) ATP-synt_ab PF00006.25 AFZ64333.1 - 4.1e-66 222.7 0.0 5.6e-66 222.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 AFZ64333.1 - 1.2e-30 106.4 0.0 2e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 AFZ64333.1 - 1.8e-10 41.2 1.1 4.1e-10 40.0 1.1 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 AFZ64333.1 - 2.4e-05 24.4 0.5 9.6e-05 22.5 0.5 2.0 2 1 0 2 2 2 1 HAS barrel domain ATPase PF06745.13 AFZ64333.1 - 0.12 11.8 0.1 0.24 10.7 0.1 1.5 1 0 0 1 1 1 0 KaiC Molybdopterin PF00384.22 AFZ64334.1 - 4.7e-44 151.0 0.0 1.5e-42 146.1 0.0 2.3 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH_dhqG_C PF09326.11 AFZ64334.1 - 0.00079 20.1 0.0 0.0019 18.8 0.0 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal COX1 PF00115.20 AFZ64335.1 - 4.3e-152 506.9 60.0 5.2e-152 506.6 60.0 1.1 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I COX1 PF00115.20 AFZ64336.1 - 2.5e-152 507.7 60.3 3e-152 507.4 60.3 1.1 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Proton_antipo_M PF00361.20 AFZ64337.1 - 5.3e-69 232.6 30.0 5.3e-69 232.6 30.0 2.1 2 0 0 2 2 2 1 Proton-conducting membrane transporter Ribosomal_S3_C PF00189.20 AFZ64338.1 - 3.6e-12 46.6 0.0 6.2e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain Complex1_49kDa PF00346.19 AFZ64339.1 - 3.7e-124 413.2 0.0 4.7e-124 412.9 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 AFZ64339.1 - 0.029 13.3 0.0 0.095 11.6 0.0 1.7 1 1 1 2 2 2 0 Nickel-dependent hydrogenase Cytochrome_B PF00033.19 AFZ64340.1 - 3.3e-79 265.1 17.7 3.3e-79 265.1 17.7 2.7 3 0 0 3 3 3 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 AFZ64340.1 - 2.8e-40 138.1 11.3 6.1e-40 137.0 11.3 1.6 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 AFZ64340.1 - 2e-37 127.6 3.7 2e-37 127.6 3.7 2.9 3 0 0 3 3 3 1 Cytochrome b(C-terminal)/b6/petD NADHdh PF00146.21 AFZ64341.1 - 1.1e-126 422.2 20.7 1.3e-126 422.0 20.7 1.0 1 0 0 1 1 1 1 NADH dehydrogenase COX2 PF00116.20 AFZ64342.1 - 4.5e-57 191.1 0.5 1.3e-48 163.9 0.0 2.4 1 1 1 2 2 2 2 Cytochrome C oxidase subunit II, periplasmic domain COX2_TM PF02790.15 AFZ64342.1 - 6.5e-27 93.5 1.5 1.4e-26 92.4 1.5 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, transmembrane domain DHHC PF01529.20 AFZ64342.1 - 0.03 14.4 1.5 0.06 13.5 1.5 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase Ribosomal_L2_C PF03947.18 AFZ64343.1 - 7.7e-52 174.8 2.4 1.5e-51 173.9 2.4 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 AFZ64343.1 - 1.6e-19 69.6 0.3 1.2e-18 66.8 0.1 2.2 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain MAAL_C PF07476.11 AFZ64343.1 - 0.12 11.5 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus COX3 PF00510.18 AFZ64344.1 - 1.1e-115 385.9 30.7 1.3e-115 385.7 30.7 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III DUF1516 PF07457.11 AFZ64344.1 - 0.084 13.1 5.1 0.41 10.9 0.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1516) ATP-synt_A PF00119.20 AFZ64345.1 - 1.3e-45 155.9 31.8 1.3e-45 155.9 31.8 1.5 1 1 1 2 2 2 1 ATP synthase A chain S4 PF01479.25 AFZ64346.1 - 1.1e-08 34.7 0.0 2.1e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 S4 domain TyrRSs_C PF16714.5 AFZ64346.1 - 0.044 13.6 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 Tyrosyl-tRNA synthetase C-terminal domain TatC PF00902.18 AFZ64347.1 - 1.5e-23 83.7 31.9 1.5e-23 83.7 31.9 1.7 1 1 1 2 2 2 1 Sec-independent protein translocase protein (TatC) AIG1 PF04548.16 AFZ64348.1 - 0.05 12.9 0.8 0.5 9.7 0.0 2.2 1 1 1 2 2 2 0 AIG1 family Ribosomal_S2 PF00318.20 AFZ64349.1 - 2.4e-27 95.6 0.1 5.2e-14 52.0 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Oxidored_q3 PF00499.20 AFZ64350.1 - 6.3e-34 116.8 24.0 9.9e-34 116.1 24.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Complex1_30kDa PF00329.19 AFZ64351.1 - 8.8e-43 145.8 0.0 1.1e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Ribosomal_L6 PF00347.23 AFZ64352.1 - 1.3e-07 32.2 0.0 1.2e-06 29.1 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L6 Ribosomal_L5_C PF00673.21 AFZ64353.1 - 2.1e-06 27.8 0.1 4.1e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 AFZ64353.1 - 0.0051 17.1 0.0 0.013 15.8 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein L5 Ribosomal_S11 PF00411.19 AFZ64354.1 - 3e-22 79.1 0.0 3.6e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Ribosomal_S7 PF00177.21 AFZ64355.1 - 3.7e-42 143.5 0.5 4.1e-42 143.3 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosomal_L16 PF00252.18 AFZ64356.1 - 3.1e-40 137.2 0.1 3.5e-40 137.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_S13 PF00416.22 AFZ64357.1 - 5.9e-19 68.7 0.3 1.5e-17 64.2 0.3 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 Ribosomal_L14 PF00238.19 AFZ64358.1 - 2.2e-37 127.9 3.4 2.4e-37 127.7 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Oxidored_q4 PF00507.19 AFZ64359.1 - 2.4e-33 114.2 8.1 3.3e-33 113.8 8.1 1.3 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 DUF1279 PF06916.13 AFZ64359.1 - 0.17 12.4 0.8 0.23 12.0 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1279) DHHC PF01529.20 AFZ64359.1 - 0.93 9.6 5.0 1.2 9.2 5.0 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase Ribosomal_S10 PF00338.22 AFZ64360.1 - 3e-13 49.8 0.3 3.2e-13 49.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Ribosomal_S14 PF00253.21 AFZ64361.1 - 2e-14 53.1 0.1 3.8e-14 52.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Ribosomal_S19 PF00203.21 AFZ64362.1 - 2e-18 66.1 0.0 2.7e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 ATP-synt_C PF00137.21 AFZ64363.1 - 3.8e-13 49.6 9.5 4.6e-13 49.3 9.5 1.1 1 0 0 1 1 1 1 ATP synthase subunit C MFS_3 PF05977.13 AFZ64363.1 - 0.12 10.7 4.3 0.13 10.6 4.3 1.0 1 0 0 1 1 1 0 Transmembrane secretion effector Retrotran_gag_2 PF14223.6 EWM19899.1 - 9.6e-09 35.0 0.1 1.1e-08 34.8 0.1 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Rop PF01815.16 EWM19899.1 - 0.033 14.0 0.1 0.054 13.4 0.1 1.3 1 0 0 1 1 1 0 Rop protein Pkinase PF00069.25 EWM19901.1 - 4.5e-18 65.5 0.1 5.1e-18 65.4 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM19901.1 - 3.3e-06 26.6 0.6 3.9e-06 26.3 0.6 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EWM19901.1 - 0.016 15.1 0.2 0.047 13.6 0.1 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family SIR2 PF02146.17 EWM19902.1 - 0.036 14.0 0.0 0.037 13.9 0.0 1.0 1 0 0 1 1 1 0 Sir2 family Taq-exonuc PF09281.10 EWM19904.1 - 0.11 12.4 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Taq polymerase, exonuclease MMR_HSR1 PF01926.23 EWM19905.1 - 0.1 12.6 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase PRORP PF16953.5 EWM19910.1 - 0.011 15.2 0.0 0.012 15.1 0.0 1.1 1 0 0 1 1 1 0 Protein-only RNase P ketoacyl-synt PF00109.26 EWM19915.1 - 1.2e-35 123.4 0.8 1.4e-35 123.1 0.8 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.23 EWM19915.1 - 0.049 13.0 0.1 0.077 12.3 0.1 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain RNB PF00773.19 EWM19922.1 - 3.8e-06 26.5 0.0 4.1e-06 26.4 0.0 1.0 1 0 0 1 1 1 1 RNB domain RVT_2 PF07727.14 EWM19924.1 - 5.4e-31 108.1 0.0 7e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Lipoxygenase PF00305.19 EWM19931.1 - 1.9e-08 33.2 0.0 2.1e-08 33.1 0.0 1.0 1 0 0 1 1 1 1 Lipoxygenase Retrotran_gag_2 PF14223.6 EWM19932.1 - 0.0018 17.9 0.0 0.0062 16.2 0.0 1.7 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type DUF1759 PF03564.15 EWM19932.1 - 0.0041 17.1 0.3 0.13 12.2 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1759) Cupin_8 PF13621.6 EWM19933.1 - 3.9e-05 23.5 0.1 5.5e-05 23.0 0.1 1.1 1 0 0 1 1 1 1 Cupin-like domain ketoacyl-synt PF00109.26 EWM19936.1 - 2.5e-30 105.9 7.4 2.8e-30 105.8 7.4 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EWM19936.1 - 0.00083 19.2 5.6 0.049 13.5 5.6 2.1 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 EWM19936.1 - 0.00093 18.6 0.4 0.001 18.5 0.4 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain BAAT_C PF08840.11 EWM19937.1 - 0.0032 17.4 0.1 0.0041 17.1 0.1 1.1 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal SCAB_CC PF16712.5 EWM19937.1 - 0.065 13.1 7.3 0.094 12.5 7.3 1.2 1 0 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein MR_MLE_N PF02746.16 EWM19937.1 - 0.32 11.2 3.0 0.5 10.6 3.0 1.2 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain TMEM18 PF14770.6 EWM19943.1 - 0.11 12.4 0.5 0.15 12.1 0.5 1.1 1 0 0 1 1 1 0 Transmembrane protein 18 ABC_tran PF00005.27 EWM19945.1 - 1.4e-06 28.9 0.0 1.8e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EWM19945.1 - 0.051 13.4 0.0 0.079 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EWM19945.1 - 0.21 11.9 0.3 4.2 7.7 0.3 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Peptidase_M16_M PF16187.5 EWM19948.1 - 1.1e-12 47.8 0.0 1.2e-12 47.7 0.0 1.0 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 zf-CCHC PF00098.23 EWM19950.1 - 0.00074 19.5 4.5 0.00074 19.5 4.5 2.1 2 0 0 2 2 2 1 Zinc knuckle eIF3g PF12353.8 EWM19950.1 - 0.035 14.5 0.8 0.057 13.8 0.8 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_3 PF13917.6 EWM19950.1 - 0.12 12.4 4.3 0.24 11.4 4.3 1.5 1 1 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 EWM19950.1 - 1.8 8.4 5.5 0.53 10.2 2.5 1.6 2 0 0 2 2 2 0 Zinc knuckle FoP_duplication PF13865.6 EWM19950.1 - 7.9 7.1 8.6 11 6.6 8.6 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 DUF5637 PF18687.1 EWM19951.1 - 0.26 11.3 0.6 0.43 10.6 0.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5637) ketoacyl-synt PF00109.26 EWM19952.1 - 4.7e-40 137.8 1.7 7.2e-40 137.2 1.7 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EWM19952.1 - 3.3e-11 43.2 0.1 7.7e-11 42.0 0.1 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EWM19952.1 - 0.00093 18.6 0.2 0.012 15.0 0.1 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain FAP PF07174.11 EWM19955.1 - 0.15 11.5 11.9 0.17 11.3 11.9 1.0 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) ORC6 PF05460.13 EWM19955.1 - 2.1 7.6 10.2 2.5 7.3 10.2 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Mito_carr PF00153.27 EWM19958.1 - 1.8e-05 24.6 0.1 0.017 15.0 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein Glyco_hydro_9 PF00759.19 EWM19961.1 - 9.9e-11 41.7 3.9 1e-10 41.6 3.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 HetR_C PF18460.1 EWM19967.1 - 0.11 12.4 0.1 1.3 8.9 0.0 2.5 3 0 0 3 3 3 0 Heterocyst differentiation regulator C-terminal Hood domain DEAD PF00270.29 EWM19969.1 - 9.4e-22 77.6 0.0 1.1e-21 77.4 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase CMS1 PF14617.6 EWM19969.1 - 2.1e-05 24.0 0.0 2.1e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Sep15_SelM PF08806.11 EWM19969.1 - 0.063 13.4 0.0 0.097 12.8 0.0 1.3 1 0 0 1 1 1 0 Sep15/SelM redox domain PseudoU_synth_2 PF00849.22 EWM19971.1 - 5.6e-05 23.3 0.0 6.9e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase EzrA PF06160.12 EWM19972.1 - 0.0023 16.2 0.0 0.0026 16.0 0.0 1.0 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Pox_A_type_inc PF04508.12 EWM19972.1 - 0.0062 16.3 2.4 1.8 8.5 0.0 2.9 3 0 0 3 3 3 2 Viral A-type inclusion protein repeat SlyX PF04102.12 EWM19972.1 - 0.13 12.9 2.2 0.22 12.2 2.2 1.5 1 1 0 1 1 1 0 SlyX Thiolase_N PF00108.23 EWM19975.1 - 0.0034 16.8 0.0 0.0039 16.6 0.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain PRP8_domainIV PF12134.8 EWM19977.1 - 4.1e-29 101.9 1.9 4.5e-29 101.7 1.9 1.0 1 0 0 1 1 1 1 PRP8 domain IV core gag_pre-integrs PF13976.6 EWM19981.1 - 2.4e-05 24.1 0.0 4.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain Golgin_A5 PF09787.9 EWM19982.1 - 0.015 14.8 2.3 0.02 14.4 2.3 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 BAAT_C PF08840.11 EWM19982.1 - 0.087 12.7 0.3 0.1 12.5 0.3 1.1 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Adenine_glyco PF03352.13 EWM19982.1 - 0.13 12.0 1.7 0.18 11.5 1.7 1.4 1 0 0 1 1 1 0 Methyladenine glycosylase SCAB_CC PF16712.5 EWM19982.1 - 0.25 11.2 14.9 2.1 8.2 7.5 2.6 1 1 1 2 2 2 0 Coiled-coil regions of plant-specific actin-binding protein Phage_Mu_Gam PF07352.12 EWM19982.1 - 0.49 10.3 9.9 0.13 12.2 3.0 2.1 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein DUF4503 PF14951.6 EWM19983.1 - 0.2 10.0 0.0 0.23 9.9 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) HEPN_RnaseLS PF18869.1 EWM19984.1 - 0.11 12.6 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 RnaseLS-like HEPN Retrotran_gag_2 PF14223.6 EWM19986.1 - 0.00074 19.2 0.0 0.0056 16.4 0.0 2.0 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type Sortilin-Vps10 PF15902.5 EWM19987.1 - 2.5e-05 23.2 2.9 4.8e-05 22.3 3.0 1.4 1 1 0 1 1 1 1 Sortilin, neurotensin receptor 3, BNR_3 PF13859.6 EWM19987.1 - 0.00074 18.9 5.6 0.15 11.3 0.5 2.0 1 1 1 2 2 2 2 BNR repeat-like domain PSII_BNR PF14870.6 EWM19987.1 - 0.0038 16.5 7.2 0.24 10.6 2.2 2.0 1 1 1 2 2 2 2 Photosynthesis system II assembly factor YCF48 BNR PF02012.20 EWM19987.1 - 0.0085 15.9 14.1 0.14 12.2 1.1 3.3 3 0 0 3 3 3 2 BNR/Asp-box repeat BNR_6 PF15899.5 EWM19987.1 - 0.0098 15.9 0.0 4.3 7.7 0.0 2.9 2 0 0 2 2 2 1 BNR-Asp box repeat Cerato-platanin PF07249.12 EWM19987.1 - 0.022 14.9 0.8 6.4 6.9 0.0 2.1 1 1 1 2 2 2 0 Cerato-platanin Rad4 PF03835.15 EWM19987.1 - 0.11 12.2 0.2 4.7 6.9 0.0 2.1 1 1 1 2 2 2 0 Rad4 transglutaminase-like domain Anophelin PF10731.9 EWM19987.1 - 0.22 11.4 0.2 7.1 6.6 0.1 2.2 1 1 1 2 2 2 0 Thrombin inhibitor from mosquito PSA_CBD PF18341.1 EWM19987.1 - 1.5 8.9 4.3 5.5 7.1 0.1 2.9 3 0 0 3 3 3 0 PSA endolysin C-terminal cell wall binding domain BAAT_C PF08840.11 EWM19988.1 - 0.0048 16.9 0.0 0.0061 16.5 0.0 1.1 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal SCAB_CC PF16712.5 EWM19988.1 - 0.058 13.2 5.5 0.083 12.7 5.5 1.2 1 0 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein Phage_Mu_Gam PF07352.12 EWM19988.1 - 0.19 11.6 6.5 0.31 11.0 6.5 1.5 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein DUF1192 PF06698.11 EWM19988.1 - 9.2 6.4 12.4 4.6 7.4 2.7 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1192) ABC2_membrane_3 PF12698.7 EWM19989.1 - 5.8e-21 75.0 1.5 6.9e-21 74.7 1.5 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein Cyclin_C PF02984.19 EWM19991.1 - 7.1e-23 81.0 0.1 9e-23 80.6 0.1 1.1 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 EWM19991.1 - 0.00023 20.9 0.1 0.06 13.1 0.0 2.3 2 1 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 EWM19991.1 - 0.14 12.5 0.1 0.22 11.9 0.1 1.4 1 1 0 1 1 1 0 Cyclin C-terminal domain ExoD PF06055.12 EWM19992.1 - 0.18 11.2 0.1 0.22 10.9 0.1 1.1 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD BAAT_C PF08840.11 EWM19993.1 - 0.082 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Cullin PF00888.22 EWM19994.1 - 4.1e-26 91.8 2.8 4.9e-26 91.5 2.8 1.0 1 0 0 1 1 1 1 Cullin family U5_2-snRNA_bdg PF10597.9 EWM19995.1 - 3.9e-33 114.4 1.2 4.3e-33 114.2 1.2 1.0 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 GIIM PF08388.11 EWM19995.1 - 0.018 15.0 0.1 0.025 14.6 0.1 1.2 1 0 0 1 1 1 0 Group II intron, maturase-specific domain ketoacyl-synt PF00109.26 EWM19998.1 - 5.7e-57 193.2 3.9 8.1e-57 192.7 3.9 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EWM19998.1 - 6.7e-11 42.2 0.1 1.5e-10 41.1 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EWM19998.1 - 5.1e-05 22.8 0.8 0.00016 21.1 0.4 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 EWM19998.1 - 0.053 13.4 1.9 0.1 12.5 0.1 2.3 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III p450 PF00067.22 EWM20002.1 - 2.8e-06 26.3 0.0 3.2e-06 26.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3989 PF13150.6 EWM20002.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) ABC_tran PF00005.27 EWM20003.1 - 3.2e-09 37.4 0.0 3.6e-09 37.3 0.0 1.0 1 0 0 1 1 1 1 ABC transporter rve PF00665.26 EWM20005.1 - 1.6e-11 44.4 0.0 2.4e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Anoctamin PF04547.12 EWM20007.1 - 4.3 6.1 7.9 6.4 5.5 7.9 1.3 1 0 0 1 1 1 0 Calcium-activated chloride channel BAAT_C PF08840.11 EWM20009.1 - 0.022 14.7 0.1 0.029 14.3 0.1 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Golgin_A5 PF09787.9 EWM20009.1 - 0.05 13.1 1.6 0.059 12.8 1.6 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 HIP1_clath_bdg PF16515.5 EWM20009.1 - 0.1 13.2 3.7 0.16 12.6 3.7 1.3 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SCAB_CC PF16712.5 EWM20009.1 - 0.15 11.9 6.3 0.23 11.3 6.3 1.2 1 0 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein Lipase_GDSL_2 PF13472.6 EWM20010.1 - 0.16 12.3 0.0 0.25 11.7 0.0 1.5 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family MG2 PF01835.19 EWM20012.1 - 0.0037 17.7 0.0 0.0095 16.4 0.0 1.7 1 1 0 1 1 1 1 MG2 domain SpaA PF17802.1 EWM20012.1 - 0.026 14.9 0.0 0.048 14.0 0.0 1.5 1 0 0 1 1 1 0 Prealbumin-like fold domain GPI-anchored PF10342.9 EWM20012.1 - 0.064 14.0 0.3 0.23 12.2 0.3 1.9 1 1 1 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF3648 PF12364.8 EWM20013.1 - 0.057 13.6 0.1 0.085 13.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3648) ketoacyl-synt PF00109.26 EWM20016.1 - 1.4e-57 195.2 2.6 2.2e-57 194.5 2.6 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EWM20016.1 - 1e-22 80.4 0.1 2e-22 79.4 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EWM20016.1 - 0.052 12.9 0.3 0.18 11.1 0.2 1.8 2 0 0 2 2 2 0 Thiolase, N-terminal domain DUF1156 PF06634.12 EWM20017.1 - 0.14 12.3 0.2 4.4 7.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1156) Golgin_A5 PF09787.9 EWM20019.1 - 0.04 13.4 1.6 0.05 13.1 1.6 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Adenine_glyco PF03352.13 EWM20019.1 - 0.058 13.2 1.2 0.081 12.7 1.2 1.2 1 0 0 1 1 1 0 Methyladenine glycosylase Phage_Mu_Gam PF07352.12 EWM20019.1 - 0.17 11.8 4.0 0.26 11.2 4.0 1.3 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein TACC_C PF05010.14 EWM20019.1 - 0.29 10.9 6.5 0.31 10.8 5.8 1.3 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal SCAB_CC PF16712.5 EWM20019.1 - 0.8 9.5 8.8 8.4 6.2 8.8 1.9 1 1 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein DUF1192 PF06698.11 EWM20019.1 - 4.2 7.5 11.6 9.1 6.4 5.7 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1192) Robl_LC7 PF03259.17 EWM20022.1 - 0.015 15.0 0.2 2.8 7.8 0.0 3.1 2 1 0 3 3 3 0 Roadblock/LC7 domain ABC_tran PF00005.27 EWM20024.1 - 7.6e-14 52.4 0.0 1e-13 52.0 0.0 1.1 1 0 0 1 1 1 1 ABC transporter TPR_2 PF07719.17 EWM20028.1 - 5.2e-06 26.2 0.0 0.029 14.5 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EWM20028.1 - 3.9e-05 24.1 0.0 0.031 15.1 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EWM20028.1 - 0.00016 22.1 0.0 0.00022 21.7 0.0 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EWM20028.1 - 0.00036 20.2 0.0 0.00047 19.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_8 PF13181.6 EWM20028.1 - 0.00071 19.6 0.0 1.6 9.1 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EWM20028.1 - 0.0052 17.0 0.0 0.0085 16.4 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 EWM20028.1 - 0.0079 15.9 0.0 0.17 11.6 0.0 2.1 1 1 1 2 2 2 1 TPR repeat TPR_17 PF13431.6 EWM20028.1 - 0.013 15.8 0.0 1.5 9.4 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 EWM20028.1 - 0.021 15.0 0.1 0.027 14.6 0.1 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 EWM20028.1 - 0.056 13.3 0.0 1 9.3 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 EWM20028.1 - 0.081 13.6 0.0 0.11 13.1 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3808 PF10300.9 EWM20028.1 - 0.15 10.8 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) Acyl_transf_1 PF00698.21 EWM20031.1 - 2e-41 142.5 0.1 2.4e-41 142.3 0.1 1.0 1 0 0 1 1 1 1 Acyl transferase domain SAT PF16073.5 EWM20031.1 - 0.00093 19.0 1.6 0.27 11.0 0.0 2.1 1 1 1 2 2 2 2 Starter unit:ACP transacylase in aflatoxin biosynthesis MAF_flag10 PF01973.18 EWM20036.1 - 0.15 11.7 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF115 hNIFK_binding PF12196.8 EWM20036.1 - 0.54 9.8 1.8 1.1 8.9 0.1 2.1 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK Retrotran_gag_2 PF14223.6 EWM20038.1 - 0.028 14.1 0.5 0.041 13.6 0.5 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Kelch_1 PF01344.25 EWM20039.1 - 0.1 12.2 0.6 0.28 10.8 0.6 1.8 1 0 0 1 1 1 0 Kelch motif DUF21 PF01595.20 EWM20040.1 - 1.6e-10 40.9 0.1 3.2e-10 40.0 0.1 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain BAAT_C PF08840.11 EWM20041.1 - 0.013 15.4 0.1 0.018 15.0 0.1 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal HIP1_clath_bdg PF16515.5 EWM20041.1 - 0.089 13.4 4.3 0.086 13.5 3.0 1.6 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Golgin_A5 PF09787.9 EWM20041.1 - 0.1 12.1 5.7 0.12 11.9 5.7 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Phage_Mu_Gam PF07352.12 EWM20041.1 - 0.2 11.5 10.6 0.27 11.1 4.5 2.1 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein SCAB_CC PF16712.5 EWM20041.1 - 0.24 11.2 7.5 0.37 10.6 7.5 1.3 1 0 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein MFS_1 PF07690.16 EWM20042.1 - 4.3e-07 29.2 7.8 4.4e-07 29.1 7.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily PUCC PF03209.15 EWM20042.1 - 0.077 12.0 2.6 0.084 11.9 2.6 1.1 1 0 0 1 1 1 0 PUCC protein Actin PF00022.19 EWM20044.1 - 8.2e-147 489.1 0.0 2.6e-146 487.4 0.0 1.6 1 1 0 1 1 1 1 Actin SBBP PF06739.11 EWM20045.1 - 0.004 17.1 3.6 0.0097 15.9 3.6 1.6 1 0 0 1 1 1 1 Beta-propeller repeat DUF1780 PF08682.10 EWM20047.1 - 0.028 14.1 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 Putative endonuclease, protein of unknown function (DUF1780) 4HB_MCP_1 PF12729.7 EWM20047.1 - 0.063 12.8 0.6 0.069 12.7 0.6 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction TPR_2 PF07719.17 EWM20048.1 - 0.0019 18.2 7.3 0.11 12.7 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EWM20048.1 - 0.0019 18.7 0.1 0.013 16.0 0.0 1.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EWM20048.1 - 0.0044 17.1 2.1 0.94 9.9 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EWM20048.1 - 0.0053 16.5 2.1 0.053 13.4 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EWM20048.1 - 0.0068 16.7 0.2 0.53 10.6 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EWM20048.1 - 0.011 15.7 0.0 0.031 14.3 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 EWM20048.1 - 0.037 13.9 1.1 0.14 12.1 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 EWM20048.1 - 0.13 12.7 2.4 0.24 11.9 0.0 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EWM20048.1 - 0.15 12.0 1.3 0.3 11.1 1.3 1.5 1 0 0 1 1 1 0 Putative TPR-like repeat ABC_tran PF00005.27 EWM20049.1 - 8.7e-07 29.5 0.0 1.3e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter Apolipoprotein PF01442.18 EWM20050.1 - 0.00055 19.9 5.9 0.00082 19.3 5.9 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain SLBB PF10531.9 EWM20050.1 - 0.033 14.1 0.0 30 4.6 0.0 3.6 3 0 0 3 3 3 0 SLBB domain Flagellin_C PF00700.21 EWM20050.1 - 0.16 12.3 4.3 16 5.9 0.3 3.8 1 1 3 4 4 4 0 Bacterial flagellin C-terminal helical region Peptidase_M75 PF09375.10 EWM20050.1 - 0.38 10.2 2.7 5.2 6.5 0.1 2.2 1 1 1 2 2 2 0 Imelysin Retrotran_gag_2 PF14223.6 EWM20053.1 - 4.1e-09 36.2 0.4 6.6e-09 35.6 0.4 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF1759 PF03564.15 EWM20053.1 - 0.00044 20.2 0.5 0.0029 17.6 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) zf-CCHC PF00098.23 EWM20053.1 - 0.0019 18.2 4.5 0.0019 18.2 4.5 2.1 2 0 0 2 2 2 1 Zinc knuckle eIF3g PF12353.8 EWM20053.1 - 0.27 11.6 3.4 0.18 12.2 0.9 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Golgin_A5 PF09787.9 EWM20054.1 - 0.011 15.3 0.7 0.014 14.9 0.7 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 HEPN_RnaseLS PF18869.1 EWM20054.1 - 0.11 12.7 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 RnaseLS-like HEPN Adenine_glyco PF03352.13 EWM20054.1 - 0.19 11.5 2.0 0.29 10.9 2.0 1.3 1 0 0 1 1 1 0 Methyladenine glycosylase Phage_TAC_4 PF08748.11 EWM20054.1 - 0.29 11.4 5.2 0.42 10.9 5.2 1.2 1 0 0 1 1 1 0 Phage tail assembly chaperone Phage_holin_7_1 PF16081.5 EWM20054.1 - 0.64 10.2 7.9 1.2 9.3 7.9 1.3 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family BAAT_C PF08840.11 EWM20060.1 - 0.065 13.1 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal MetallophosC PF16370.5 EWM20060.1 - 0.1 12.8 0.6 0.12 12.6 0.6 1.3 1 1 0 1 1 1 0 C terminal of Calcineurin-like phosphoesterase SCAB_CC PF16712.5 EWM20060.1 - 0.33 10.8 7.2 0.48 10.2 7.2 1.2 1 0 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein Phage_Mu_Gam PF07352.12 EWM20060.1 - 0.41 10.6 8.8 0.16 11.9 3.1 2.0 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein UBA_4 PF14555.6 EWM20062.1 - 0.064 13.1 0.2 1.2 9.0 0.2 2.1 1 1 1 2 2 2 0 UBA-like domain PRIMA1 PF16101.5 EWM20065.1 - 0.64 10.1 9.8 0.87 9.6 9.8 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 EWM20065.1 - 1.1 8.7 4.5 1.3 8.5 4.5 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Rsm22 PF09243.10 EWM20067.1 - 0.044 13.0 0.3 0.051 12.8 0.3 1.0 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Collagen PF01391.18 EWM20068.1 - 3.7e-09 36.2 22.0 5.2e-09 35.7 22.0 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) RVT_2 PF07727.14 EWM20071.1 - 1.9e-68 230.7 0.0 2.2e-68 230.5 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PheRS_DBD3 PF18553.1 EWM20071.1 - 0.08 13.2 0.1 2.1 8.7 0.0 2.4 2 0 0 2 2 2 0 PheRS DNA binding domain 3 PhyH PF05721.13 EWM20072.1 - 3.6e-10 40.4 0.1 5.2e-10 39.9 0.1 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PHD_Oberon PF07227.11 EWM20073.1 - 0.0095 15.8 0.3 0.013 15.4 0.3 1.3 1 0 0 1 1 1 1 PHD - plant homeodomain finger protein Cation_ATPase PF13246.6 EWM20076.1 - 1e-08 35.1 0.0 2e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) DUF2073 PF09846.9 EWM20076.1 - 0.11 12.4 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2073) DUF5050 PF16472.5 EWM20077.1 - 5e-05 22.7 1.0 6.4e-05 22.3 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5050) PQQ_3 PF13570.6 EWM20077.1 - 1 10.0 8.1 1.2 9.7 0.2 3.1 4 0 0 4 4 4 0 PQQ-like domain FBPase PF00316.20 EWM20080.1 - 1.7e-19 70.0 0.2 2.2e-19 69.7 0.2 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain MU2_FHA PF18221.1 EWM20080.1 - 0.026 14.6 0.1 0.059 13.4 0.0 1.6 2 0 0 2 2 2 0 Mutator 2 Fork head associated domain Myb_DNA-binding PF00249.31 EWM20081.1 - 5.1e-10 39.4 1.0 8e-10 38.8 1.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EWM20081.1 - 0.2 11.6 0.1 0.3 11.0 0.1 1.3 1 0 0 1 1 1 0 Myb DNA-binding like DUF4407 PF14362.6 EWM20082.1 - 0.0013 18.1 6.5 0.002 17.5 6.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) DUF4618 PF15397.6 EWM20082.1 - 0.0077 15.7 0.4 0.013 15.0 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) BAAT_C PF08840.11 EWM20082.1 - 0.022 14.7 0.1 0.031 14.2 0.1 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Golgin_A5 PF09787.9 EWM20082.1 - 0.068 12.6 6.7 0.092 12.2 6.7 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Phage_Mu_Gam PF07352.12 EWM20082.1 - 0.074 13.0 15.2 15 5.4 2.2 2.2 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein Muted PF14942.6 EWM20082.1 - 0.078 13.3 2.8 0.11 12.8 2.8 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Spc7 PF08317.11 EWM20082.1 - 0.31 9.9 8.3 0.42 9.5 8.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 EWM20082.1 - 0.75 10.4 7.9 0.26 11.9 3.0 2.0 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Atg14 PF10186.9 EWM20082.1 - 0.92 8.5 3.1 1.3 8.0 3.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 EWM20082.1 - 2.2 7.4 5.9 8.1 5.6 5.0 1.6 1 1 0 1 1 1 0 TMPIT-like protein DUF1192 PF06698.11 EWM20082.1 - 2.4 8.3 21.9 12 6.0 5.6 4.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) DUF4140 PF13600.6 EWM20082.1 - 4 7.9 11.0 11 6.5 11.0 1.8 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) SCAB_CC PF16712.5 EWM20082.1 - 4.2 7.2 15.5 60 3.4 2.1 2.0 1 1 1 2 2 2 0 Coiled-coil regions of plant-specific actin-binding protein Lipase_3 PF01764.25 EWM20084.1 - 0.00013 21.8 0.0 0.00015 21.6 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) Corona_NS2 PF04753.12 EWM20084.1 - 0.062 13.9 0.0 0.078 13.6 0.0 1.2 1 0 0 1 1 1 0 Coronavirus non-structural protein NS2 rve PF00665.26 EWM20093.1 - 4.2e-17 62.4 0.0 7.5e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain PCYCGC PF13798.6 EWM20094.1 - 0.31 10.9 0.9 0.54 10.1 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function with PCYCGC motif ketoacyl-synt PF00109.26 EWM20096.1 - 7.9e-85 284.5 1.8 1.2e-84 283.9 1.8 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EWM20096.1 - 4.3e-22 78.4 0.1 8.3e-22 77.4 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 EWM20096.1 - 2.3e-08 34.2 0.1 4.4e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 EWM20096.1 - 0.0004 19.8 1.3 0.00055 19.4 0.2 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 EWM20096.1 - 0.011 15.6 1.7 0.03 14.2 0.1 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Urm1 PF09138.11 EWM20099.1 - 2.6e-06 27.7 0.1 2.9 8.3 0.0 4.2 3 1 1 4 4 4 2 Urm1 (Ubiquitin related modifier) OapA PF04225.12 EWM20099.1 - 1.9e-05 24.7 0.0 2.2 8.4 0.0 4.3 5 0 0 5 5 5 2 Opacity-associated protein A LysM-like domain LVIVD PF08309.11 EWM20099.1 - 0.00048 19.4 5.1 16 4.9 0.0 4.7 4 0 0 4 4 4 4 LVIVD repeat YHYH PF14240.6 EWM20099.1 - 0.0026 17.7 3.1 3.4 7.6 0.2 4.1 2 1 1 3 3 3 1 YHYH protein DUF5050 PF16472.5 EWM20099.1 - 0.017 14.4 0.1 0.074 12.3 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5050) APC_r PF05923.12 EWM20099.1 - 3.3 7.5 14.0 20 5.1 0.3 4.3 4 0 0 4 4 4 0 APC repeat DUF667 PF05018.13 EWM20102.1 - 3.6e-30 105.1 0.0 4.2e-30 104.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Peptidase_M8 PF01457.16 EWM20104.1 - 7.1e-06 25.0 0.0 9.1e-06 24.6 0.0 1.1 1 0 0 1 1 1 1 Leishmanolysin SprT-like PF10263.9 EWM20104.1 - 0.017 14.9 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 SprT-like family CrtC PF07143.11 EWM20106.1 - 0.12 13.1 0.4 0.14 12.8 0.4 1.1 1 0 0 1 1 1 0 CrtC N-terminal lipocalin domain Sulfotransfer_2 PF03567.14 EWM20106.1 - 0.15 12.0 0.0 0.19 11.6 0.0 1.1 1 0 0 1 1 1 0 Sulfotransferase family PT PF04886.12 EWM20109.1 - 0.0025 17.3 75.3 0.0084 15.6 32.6 3.5 2 1 1 3 3 3 3 PT repeat Hamartin PF04388.12 EWM20109.1 - 1.6 7.3 6.8 1.8 7.1 6.8 1.1 1 0 0 1 1 1 0 Hamartin protein Fungus-induced PF10917.8 EWM20112.1 - 0.02 15.2 1.7 0.031 14.6 1.0 1.6 2 0 0 2 2 2 0 Fungus-induced protein DUF4366 PF14283.6 EWM20112.1 - 0.11 12.5 0.2 0.13 12.3 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) K_channel_TID PF07941.11 EWM20112.1 - 0.15 12.6 11.0 0.38 11.2 4.2 2.1 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain HEPN_RnaseLS PF18869.1 EWM20114.1 - 0.094 12.8 0.1 0.14 12.3 0.1 1.2 1 0 0 1 1 1 0 RnaseLS-like HEPN ABC_tran PF00005.27 EWM20116.1 - 1.1e-09 39.0 0.0 1.5e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EWM20116.1 - 7.6e-06 25.9 0.0 1.1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 EWM20116.1 - 0.065 12.0 0.1 0.41 9.4 0.1 1.9 1 1 0 1 1 1 0 Predicted ATPase of the ABC class Xan_ur_permease PF00860.20 EWM20117.1 - 5.7e-05 22.0 0.2 6.6e-05 21.8 0.2 1.0 1 0 0 1 1 1 1 Permease family zf-C2HCIx2C PF10782.9 EWM20117.1 - 0.041 13.8 0.1 0.068 13.1 0.1 1.3 1 0 0 1 1 1 0 Zinc-finger DUF5464 PF17552.2 EWM20117.1 - 0.16 12.2 2.7 0.55 10.5 2.7 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5464) Spc7 PF08317.11 EWM20119.1 - 0.0095 14.8 9.0 0.013 14.4 9.0 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein FAM76 PF16046.5 EWM20119.1 - 0.013 14.9 0.4 0.019 14.3 0.4 1.2 1 0 0 1 1 1 0 FAM76 protein DUF1640 PF07798.11 EWM20119.1 - 0.015 15.4 5.8 0.056 13.5 4.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) BAAT_C PF08840.11 EWM20119.1 - 0.017 15.0 0.2 0.025 14.5 0.2 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal SPATA1_C PF15743.5 EWM20119.1 - 0.06 13.4 4.8 0.12 12.4 4.8 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus Phage_Mu_Gam PF07352.12 EWM20119.1 - 0.081 12.8 13.1 0.063 13.2 10.6 1.9 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein DUF4549 PF15082.6 EWM20119.1 - 0.16 11.8 2.4 0.27 11.0 0.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4549) Golgin_A5 PF09787.9 EWM20119.1 - 0.29 10.5 6.6 0.93 8.9 6.6 1.7 1 1 0 1 1 1 0 Golgin subfamily A member 5 TMPIT PF07851.13 EWM20119.1 - 0.3 10.3 6.8 0.017 14.4 1.4 1.5 2 0 0 2 2 2 0 TMPIT-like protein Atg14 PF10186.9 EWM20119.1 - 0.56 9.2 4.2 0.79 8.8 4.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_MLP1_2 PF07926.12 EWM20119.1 - 0.6 10.2 13.7 5.6 7.0 13.8 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein SCAB_CC PF16712.5 EWM20119.1 - 0.76 9.6 15.8 4.5 7.1 15.8 1.9 1 1 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein DivIC PF04977.15 EWM20119.1 - 3.7 7.4 12.7 12 5.7 4.8 2.5 1 1 1 2 2 2 0 Septum formation initiator DUF4140 PF13600.6 EWM20119.1 - 5.3 7.5 15.1 3 8.3 4.8 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) zf-like PF04071.12 EWM20121.1 - 0.4 10.6 1.9 7 6.6 0.1 2.9 3 0 0 3 3 3 0 Cysteine-rich small domain Ank_2 PF12796.7 EWM20122.1 - 0.00049 20.6 0.0 0.001 19.6 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EWM20122.1 - 0.0012 19.2 1.3 0.26 11.8 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EWM20122.1 - 0.011 16.2 1.6 7.3 7.5 0.1 2.9 3 0 0 3 3 3 0 Ankyrin repeat rve PF00665.26 EWM20124.1 - 2.1e-19 69.8 0.0 3.4e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 EWM20124.1 - 1.8e-08 34.1 0.0 4e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 EWM20124.1 - 0.064 13.0 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Val_tRNA-synt_C PF10458.9 EWM20131.1 - 4e-14 52.6 3.2 7.5e-14 51.8 3.2 1.5 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm ABC_tran_CTD PF16326.5 EWM20131.1 - 0.0057 16.9 1.5 0.013 15.7 1.5 1.5 1 0 0 1 1 1 1 ABC transporter C-terminal domain DUF5082 PF16888.5 EWM20131.1 - 0.043 14.1 0.3 0.07 13.4 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) gag_pre-integrs PF13976.6 EWM20134.1 - 8.2e-07 28.8 0.0 2.2e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.23 EWM20134.1 - 0.0032 17.5 3.0 0.0032 17.5 3.0 3.1 3 0 0 3 3 3 1 Zinc knuckle zf-CCHC_2 PF13696.6 EWM20134.1 - 1.8 8.5 10.6 0.065 13.1 2.6 2.5 2 0 0 2 2 2 0 Zinc knuckle YuzL PF14115.6 EWM20137.1 - 3.2 8.3 4.9 1.6 9.3 0.7 2.4 2 0 0 2 2 2 0 YuzL-like protein E1_UFD PF09358.10 EWM20138.1 - 7e-29 100.4 0.0 9.3e-29 100.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fold domain WD-3 PF09765.9 EWM20139.1 - 8.1e-10 38.5 0.0 1.3e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 WD-repeat region Aa_trans PF01490.18 EWM20142.1 - 1.3e-21 76.8 10.1 1.5e-21 76.6 10.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PT PF04886.12 EWM20143.1 - 3.4e-07 29.7 142.5 0.023 14.3 14.0 6.5 2 1 4 6 6 6 5 PT repeat SOG2 PF10428.9 EWM20143.1 - 7.7 5.6 12.6 10 5.2 12.6 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein CiPC PF15800.5 EWM20144.1 - 0.021 14.6 1.2 0.026 14.3 1.2 1.0 1 0 0 1 1 1 0 Clock interacting protein circadian Phage_Mu_Gam PF07352.12 EWM20145.1 - 0.093 12.6 4.9 0.13 12.1 4.9 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein BAAT_C PF08840.11 EWM20145.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1192 PF06698.11 EWM20145.1 - 4.3 7.5 9.8 4.2 7.5 2.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) Phage_Mu_Gam PF07352.12 EWM20146.1 - 0.027 14.4 4.0 0.039 13.9 4.0 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein BAAT_C PF08840.11 EWM20146.1 - 0.055 13.4 0.0 0.067 13.1 0.0 1.1 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal SCAB_CC PF16712.5 EWM20146.1 - 0.067 13.0 2.7 0.09 12.6 2.7 1.2 1 0 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein DUF1192 PF06698.11 EWM20146.1 - 1.7 8.7 10.0 6.6 6.9 3.9 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) SCP_3 PF17844.1 EWM20148.1 - 0.048 13.4 0.2 1.3 8.8 0.0 2.9 2 1 0 3 3 3 0 Bacterial SCP ortholog DUF3494 PF11999.8 EWM20148.1 - 0.11 12.2 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3494) PT PF04886.12 EWM20154.1 - 0.00016 21.1 15.8 0.00016 21.1 15.8 4.0 2 1 0 2 2 2 1 PT repeat Spc7_N PF15402.6 EWM20154.1 - 2.9 6.0 9.8 3.7 5.7 9.8 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 RVT_2 PF07727.14 EWM20156.1 - 8.8e-37 127.0 0.0 1.3e-36 126.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 EWM20156.1 - 2.3e-19 69.7 0.0 4.6e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 EWM20156.1 - 5.6e-08 32.5 0.0 1.1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF3213 PF11491.8 EWM20156.1 - 0.18 12.0 0.0 0.42 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) PyrI_C PF02748.15 EWM20157.1 - 0.19 11.6 2.5 1.6 8.7 2.5 2.0 1 1 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Nucleotid_trans PF03407.16 EWM20159.1 - 1e-05 25.7 0.0 1.4e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF1445 PF07286.12 EWM20161.1 - 0.067 13.1 0.0 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1445) FNIP_M PF14637.6 EWM20161.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain ADH_zinc_N PF00107.26 EWM20163.1 - 2.8e-14 53.2 0.0 5.1e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PS-DH PF14765.6 EWM20163.1 - 1.2e-13 51.0 0.0 2.8e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_N PF08240.12 EWM20163.1 - 4.7e-07 29.7 0.2 1.3e-06 28.2 0.2 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EWM20163.1 - 0.00012 23.1 0.0 0.00031 21.8 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EWM20163.1 - 0.00071 18.9 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain BAAT_C PF08840.11 EWM20166.1 - 0.013 15.5 0.1 0.019 14.9 0.1 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal SCAB_CC PF16712.5 EWM20166.1 - 0.22 11.4 15.0 0.055 13.3 2.5 2.1 1 1 1 2 2 2 0 Coiled-coil regions of plant-specific actin-binding protein Golgin_A5 PF09787.9 EWM20166.1 - 0.27 10.6 5.1 0.37 10.2 5.1 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 TPR_MLP1_2 PF07926.12 EWM20166.1 - 0.81 9.8 10.6 2.7 8.1 2.0 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF5415 PF17436.2 EWM20166.1 - 1.8 8.7 8.2 11 6.2 1.1 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5415) DUF1690 PF07956.11 EWM20166.1 - 6.9 7.1 8.6 17 5.9 8.5 1.5 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) Glyco_transf_64 PF09258.10 EWM20167.1 - 9.1e-28 97.2 0.0 1.4e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Methyltransf_24 PF13578.6 EWM20167.1 - 3.2e-07 31.3 0.1 0.0002 22.3 0.0 2.8 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 EWM20167.1 - 5.3e-06 26.4 0.0 1.9e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EWM20167.1 - 0.00014 22.6 0.0 0.00054 20.7 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM20167.1 - 0.0017 18.9 0.0 0.0057 17.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM20167.1 - 0.086 12.6 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain RVT_2 PF07727.14 EWM20168.1 - 2e-29 103.0 0.0 3.1e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 EWM20168.1 - 5.7e-19 68.5 0.0 1.1e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 EWM20168.1 - 2.4e-08 33.7 0.0 4.6e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 EWM20168.1 - 0.16 11.8 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain CDC45 PF02724.14 EWM20168.1 - 4.7 5.4 6.3 6.3 5.0 6.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Glycos_transf_2 PF00535.26 EWM20169.1 - 6.1e-08 32.7 0.0 8.2e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.6 EWM20169.1 - 0.00015 22.2 0.0 0.00021 21.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 RRM_1 PF00076.22 EWM20172.1 - 0.0043 16.8 0.0 0.0082 15.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) baeRF_family2 PF18844.1 EWM20178.1 - 0.0092 16.1 0.4 0.01 15.9 0.4 1.1 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 2 YqfQ PF14181.6 EWM20178.1 - 0.14 12.4 0.9 0.16 12.2 0.9 1.1 1 0 0 1 1 1 0 YqfQ-like protein TolA PF06519.11 EWM20180.1 - 0.084 13.1 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 TolA C-terminal Trigger_N PF05697.13 EWM20183.1 - 0.013 15.8 0.0 0.02 15.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) CRIM PF16978.5 EWM20183.1 - 0.21 11.7 0.0 0.3 11.2 0.0 1.2 1 0 0 1 1 1 0 SAPK-interacting protein 1 (Sin1), middle CRIM domain BK_channel_a PF03493.18 EWM20186.1 - 0.082 13.1 2.8 3.6 7.8 0.1 2.6 2 1 1 3 3 3 0 Calcium-activated BK potassium channel alpha subunit RVT_2 PF07727.14 EWM20187.1 - 2e-54 184.8 0.0 1.3e-52 178.8 0.0 2.5 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 EWM20187.1 - 1.3e-11 44.7 0.0 4.4e-11 43.0 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain fn3 PF00041.21 EWM20188.1 - 2.2e-19 69.6 3.7 1.2e-08 35.2 0.3 2.7 3 0 0 3 3 3 2 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 EWM20188.1 - 0.0084 16.7 2.1 0.37 11.4 0.2 2.6 2 0 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain IN_DBD_C PF00552.21 EWM20190.1 - 0.0021 17.3 0.0 0.0039 16.5 0.0 1.4 1 0 0 1 1 1 1 Integrase DNA binding domain Glyco_transf_64 PF09258.10 EWM20194.1 - 1e-20 74.1 0.0 1.4e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain DUF563 PF04577.14 EWM20196.1 - 2.7e-22 80.0 0.0 4.4e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DUF563 PF04577.14 EWM20197.1 - 2.6e-22 80.0 0.0 4.3e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Retrotran_gag_2 PF14223.6 EWM20198.1 - 0.013 15.2 0.2 0.014 15.1 0.2 1.0 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type RVT_2 PF07727.14 EWM20200.1 - 7e-69 232.1 0.0 1.9e-68 230.7 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DEDD_Tnp_IS110 PF01548.17 EWM20200.1 - 0.072 13.0 0.2 0.14 12.0 0.2 1.4 1 0 0 1 1 1 0 Transposase FAM219A PF15260.6 EWM20200.1 - 1.2 9.5 4.2 4.6 7.6 1.9 2.5 2 0 0 2 2 2 0 Protein family FAM219A MFS_1 PF07690.16 EWM20208.1 - 3.7e-26 91.9 22.5 4.7e-26 91.6 22.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EWM20208.1 - 6.7e-08 31.8 6.0 6.7e-08 31.8 6.0 2.0 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 EWM20208.1 - 0.00015 21.2 6.4 0.00018 20.9 6.4 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 EWM20208.1 - 0.00073 18.5 3.7 0.00073 18.5 3.7 1.9 1 1 0 2 2 2 1 MFS_1 like family LacY_symp PF01306.19 EWM20208.1 - 0.19 10.4 8.3 0.25 10.1 8.3 1.1 1 0 0 1 1 1 0 LacY proton/sugar symporter MFS_2 PF13347.6 EWM20208.1 - 0.25 9.9 10.5 0.031 12.8 5.9 1.6 1 1 1 2 2 2 0 MFS/sugar transport protein OATP PF03137.20 EWM20208.1 - 1.2 7.4 8.9 0.18 10.0 3.0 2.1 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 EWM20208.1 - 5.6 5.2 8.0 28 2.9 8.0 1.8 1 1 0 1 1 1 0 Transmembrane secretion effector Glycos_transf_2 PF00535.26 EWM20210.1 - 0.00026 20.9 0.2 0.00065 19.5 0.2 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 2 FAD_binding_4 PF01565.23 EWM20212.1 - 5.1e-24 84.6 2.5 1.2e-23 83.3 2.5 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EWM20212.1 - 9.8e-07 28.8 0.3 2.6e-06 27.4 0.3 1.7 1 0 0 1 1 1 1 Berberine and berberine like AvrPtoB-E3_ubiq PF09046.10 EWM20215.1 - 0.12 12.7 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 AvrPtoB E3 ubiquitin ligase RVT_2 PF07727.14 EWM20216.1 - 4.4e-22 78.9 0.0 4.8e-22 78.8 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EGF_2 PF07974.13 EWM20217.1 - 0.001 19.4 1.0 0.001 19.4 1.0 1.9 3 0 0 3 3 3 1 EGF-like domain RVT_2 PF07727.14 EWM20220.1 - 9.7e-08 31.9 0.0 1.3e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MGAT2 PF05060.14 EWM20221.1 - 0.018 14.1 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 N-acetylglucosaminyltransferase II (MGAT2) DUF5134 PF17197.4 EWM20226.1 - 0.015 15.2 0.3 0.019 14.9 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5134) DUF1690 PF07956.11 EWM20226.1 - 0.057 13.8 7.9 0.082 13.3 7.9 1.1 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) SWI-SNF_Ssr4 PF08549.10 EWM20226.1 - 0.061 12.0 3.5 0.072 11.7 3.5 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Phage_Mu_Gam PF07352.12 EWM20226.1 - 0.073 13.0 5.8 0.17 11.8 5.7 1.8 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein Glyoxalase PF00903.25 EWM20227.1 - 2.1e-09 37.7 0.0 8.3e-08 32.5 0.0 2.2 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF3081 PF11280.8 EWM20227.1 - 0.0011 18.8 0.2 0.14 12.0 0.0 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF3081) Glyoxalase_6 PF18029.1 EWM20227.1 - 0.025 15.4 3.3 3.1 8.6 0.0 3.3 2 2 0 2 2 2 0 Glyoxalase-like domain V-SNARE PF05008.15 EWM20230.1 - 0.13 12.6 0.1 0.3 11.5 0.1 1.6 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Baculo_PEP_C PF04513.12 EWM20230.1 - 0.19 11.8 0.0 0.27 11.3 0.0 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3213 PF11491.8 EWM20231.1 - 0.16 12.2 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Retrotran_gag_2 PF14223.6 EWM20232.1 - 4e-08 33.0 0.3 6.6e-08 32.3 0.3 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF1759 PF03564.15 EWM20232.1 - 0.0091 15.9 0.5 0.04 13.9 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) DUF2019 PF09450.10 EWM20233.1 - 0.0014 18.5 0.0 0.0019 18.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2019) EzrA PF06160.12 EWM20233.1 - 0.0071 14.6 0.9 0.0083 14.4 0.9 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA TolA_bind_tri PF16331.5 EWM20233.1 - 0.0093 16.0 0.2 0.36 10.9 0.0 2.2 2 0 0 2 2 2 1 TolA binding protein trimerisation Syntaxin_2 PF14523.6 EWM20233.1 - 0.017 15.5 0.2 0.021 15.2 0.2 1.1 1 0 0 1 1 1 0 Syntaxin-like protein TTRAP PF14203.6 EWM20233.1 - 0.034 14.1 0.3 0.1 12.6 0.2 2.0 1 1 1 2 2 2 0 Putative tranposon-transfer assisting protein Fib_alpha PF08702.10 EWM20233.1 - 0.038 14.2 0.5 0.052 13.7 0.5 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Tox-REase-7 PF15649.6 EWM20233.1 - 0.045 14.1 0.3 0.19 12.0 0.3 1.8 1 1 1 2 2 2 0 Restriction endonuclease fold toxin 7 DUF4164 PF13747.6 EWM20233.1 - 0.085 13.1 0.4 0.6 10.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) RVT_2 PF07727.14 EWM20234.1 - 2.7e-44 151.6 0.0 3.6e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ATP_synt_H PF05493.13 EWM20235.1 - 0.03 14.8 3.2 0.049 14.1 3.2 1.6 1 1 0 1 1 1 0 ATP synthase subunit H Epimerase PF01370.21 EWM20236.1 - 1.2e-30 106.7 0.0 1.9e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EWM20236.1 - 4.9e-30 105.1 0.0 7.4e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Exostosin PF03016.15 EWM20236.1 - 8.8e-30 103.9 0.0 1.9e-29 102.8 0.0 1.6 1 1 0 1 1 1 1 Exostosin family RmlD_sub_bind PF04321.17 EWM20236.1 - 1.9e-13 50.1 0.0 3.1e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 EWM20236.1 - 1.7e-12 47.0 0.0 2.7e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EWM20236.1 - 5.1e-09 35.7 0.0 6.3e-08 32.1 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EWM20236.1 - 5.6e-08 32.3 0.0 1.4e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 EWM20236.1 - 6.9e-07 28.9 0.0 1.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EWM20236.1 - 1.1e-06 28.7 0.0 1.8e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 EWM20236.1 - 0.014 15.0 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family SQHop_cyclase_C PF13243.6 EWM20236.1 - 0.02 14.0 0.1 0.044 12.9 0.0 1.5 2 0 0 2 2 2 0 Squalene-hopene cyclase C-terminal domain adh_short_C2 PF13561.6 EWM20236.1 - 0.04 13.5 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase 2-Hacid_dh_C PF02826.19 EWM20236.1 - 0.17 11.2 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 EWM20237.1 - 1.2e-30 106.7 0.0 1.9e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EWM20237.1 - 4.9e-30 105.1 0.0 7.4e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Exostosin PF03016.15 EWM20237.1 - 8.8e-30 103.9 0.0 1.9e-29 102.8 0.0 1.6 1 1 0 1 1 1 1 Exostosin family RmlD_sub_bind PF04321.17 EWM20237.1 - 1.9e-13 50.1 0.0 3.1e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 EWM20237.1 - 1.7e-12 47.0 0.0 2.7e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EWM20237.1 - 5.1e-09 35.7 0.0 6.3e-08 32.1 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EWM20237.1 - 5.6e-08 32.3 0.0 1.4e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 EWM20237.1 - 6.9e-07 28.9 0.0 1.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EWM20237.1 - 1.1e-06 28.7 0.0 1.8e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 EWM20237.1 - 0.014 15.0 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family SQHop_cyclase_C PF13243.6 EWM20237.1 - 0.02 14.0 0.1 0.044 12.9 0.0 1.5 2 0 0 2 2 2 0 Squalene-hopene cyclase C-terminal domain adh_short_C2 PF13561.6 EWM20237.1 - 0.04 13.5 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase 2-Hacid_dh_C PF02826.19 EWM20237.1 - 0.17 11.2 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 EWM20243.1 - 3.3e-31 108.6 0.0 5e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EWM20243.1 - 7.5e-31 107.7 0.0 1.1e-30 107.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Exostosin PF03016.15 EWM20243.1 - 7.6e-31 107.4 0.0 1.7e-30 106.3 0.0 1.6 1 1 0 1 1 1 1 Exostosin family RmlD_sub_bind PF04321.17 EWM20243.1 - 1.9e-13 50.2 0.0 3.1e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 EWM20243.1 - 7.2e-13 48.2 0.0 1.1e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EWM20243.1 - 2.2e-09 36.9 0.0 2.7e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EWM20243.1 - 1.9e-07 30.8 0.0 3.4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 EWM20243.1 - 2e-07 30.5 0.0 5.2e-07 29.1 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 EWM20243.1 - 7.9e-07 29.1 0.0 1.3e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EWM20243.1 - 0.013 15.0 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase SQHop_cyclase_C PF13243.6 EWM20243.1 - 0.015 14.4 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain NmrA PF05368.13 EWM20243.1 - 0.024 14.2 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family 2-Hacid_dh_C PF02826.19 EWM20243.1 - 0.22 10.9 0.0 0.38 10.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 EWM20244.1 - 3.3e-31 108.6 0.0 5e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EWM20244.1 - 7.5e-31 107.7 0.0 1.1e-30 107.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Exostosin PF03016.15 EWM20244.1 - 7.6e-31 107.4 0.0 1.7e-30 106.3 0.0 1.6 1 1 0 1 1 1 1 Exostosin family RmlD_sub_bind PF04321.17 EWM20244.1 - 1.9e-13 50.2 0.0 3.1e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 EWM20244.1 - 7.2e-13 48.2 0.0 1.1e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EWM20244.1 - 2.2e-09 36.9 0.0 2.7e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EWM20244.1 - 1.9e-07 30.8 0.0 3.4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 EWM20244.1 - 2e-07 30.5 0.0 5.2e-07 29.1 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 EWM20244.1 - 7.9e-07 29.1 0.0 1.3e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EWM20244.1 - 0.013 15.0 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase SQHop_cyclase_C PF13243.6 EWM20244.1 - 0.015 14.4 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain NmrA PF05368.13 EWM20244.1 - 0.024 14.2 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family 2-Hacid_dh_C PF02826.19 EWM20244.1 - 0.22 10.9 0.0 0.38 10.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glycos_transf_2 PF00535.26 EWM20245.1 - 3.9e-08 33.3 0.0 5.1e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.6 EWM20245.1 - 0.0001 22.7 0.0 0.00014 22.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 PT PF04886.12 EWM20247.1 - 8.1e-11 41.3 65.4 46 3.7 50.6 4.1 2 1 0 2 2 2 1 PT repeat BNR PF02012.20 EWM20247.1 - 0.04 13.9 1.1 1.1 9.5 0.2 3.2 3 0 0 3 3 3 0 BNR/Asp-box repeat Alpha_adaptinC2 PF02883.20 EWM20247.1 - 0.12 12.7 1.1 0.18 12.1 0.0 1.8 2 0 0 2 2 2 0 Adaptin C-terminal domain OB_Dis3 PF17849.1 EWM20249.1 - 1.4e-12 47.4 0.0 2.5e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 EWM20249.1 - 0.0016 18.2 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 Rrp44-like cold shock domain CSD2 PF17876.1 EWM20249.1 - 0.0072 16.5 0.1 0.018 15.2 0.1 1.7 2 0 0 2 2 2 1 Cold shock domain OB_RNB PF08206.11 EWM20249.1 - 0.017 14.8 0.0 0.072 12.8 0.0 2.1 2 0 0 2 2 2 0 Ribonuclease B OB domain WW PF00397.26 EWM20250.1 - 4.4e-14 52.3 3.6 4.4e-08 33.1 1.4 2.8 2 0 0 2 2 2 2 WW domain SUN PF03856.13 EWM20251.1 - 5.2e-12 45.7 6.4 2.2e-05 24.1 0.1 2.6 2 0 0 2 2 2 2 Beta-glucosidase (SUN family) G8 PF10162.9 EWM20251.1 - 3.1e-05 24.1 0.0 8.3e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 G8 domain Chlam_PMP PF02415.17 EWM20252.1 - 0.072 13.6 0.6 0.072 13.6 0.6 6.1 7 0 0 7 7 7 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat RVT_2 PF07727.14 EWM20259.1 - 5e-06 26.3 0.0 8.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 EWM20259.1 - 0.039 14.1 0.0 0.097 12.9 0.0 1.6 2 0 0 2 2 2 0 Integrase core domain RVT_2 PF07727.14 EWM20261.1 - 9.9e-41 140.0 0.0 4.3e-39 134.6 0.0 2.4 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) DEDD_Tnp_IS110 PF01548.17 EWM20262.1 - 0.004 17.0 0.1 0.0051 16.7 0.1 1.1 1 0 0 1 1 1 1 Transposase DUF4376 PF14301.6 EWM20262.1 - 0.057 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4376) DEDD_Tnp_IS110 PF01548.17 EWM20263.1 - 0.004 17.0 0.1 0.0051 16.7 0.1 1.1 1 0 0 1 1 1 1 Transposase DUF4376 PF14301.6 EWM20263.1 - 0.057 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4376) Retrotran_gag_2 PF14223.6 EWM20264.1 - 4.9e-10 39.2 0.4 7.4e-10 38.6 0.4 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF1759 PF03564.15 EWM20264.1 - 0.0001 22.3 0.5 0.00055 19.9 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) zf-CCHC_5 PF14787.6 EWM20264.1 - 1 9.2 4.6 5.4 6.8 3.3 2.4 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger STELLO PF03385.17 EWM20265.1 - 2.9e-16 59.3 0.0 4.4e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 STELLO glycosyltransferases Glyco_tranf_2_4 PF13704.6 EWM20265.1 - 7e-06 26.5 0.1 2e-05 25.0 0.1 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 TT1725 PF18324.1 EWM20265.1 - 0.12 12.5 0.0 12 6.0 0.0 2.4 2 0 0 2 2 2 0 Hypothetical protein TT1725 Retrotran_gag_2 PF14223.6 EWM20266.1 - 2.8e-05 23.8 0.8 3.6e-05 23.4 0.8 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type KH_7 PF17214.3 EWM20266.1 - 0.11 12.5 0.1 0.86 9.6 0.0 2.2 1 1 1 2 2 2 0 KH domain zf-CCHC_5 PF14787.6 EWM20266.1 - 0.18 11.5 4.6 2.1 8.1 3.3 2.6 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger RVT_2 PF07727.14 EWM20268.1 - 0.05 13.2 0.0 0.062 12.9 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Sulfotransfer_2 PF03567.14 EWM20269.1 - 3.6e-10 40.2 0.1 4.3e-08 33.4 0.0 2.1 2 0 0 2 2 2 2 Sulfotransferase family SF-assemblin PF06705.11 EWM20272.1 - 0.043 13.2 0.0 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin DUF3889 PF13028.6 EWM20273.1 - 0.12 12.3 0.1 6.4 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3889) GCP_C_terminal PF04130.13 EWM20277.1 - 6e-05 22.7 0.0 8.1e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal TIP49_C PF17856.1 EWM20278.1 - 6.1e-21 74.3 0.1 7.8e-21 74.0 0.1 1.1 1 0 0 1 1 1 1 TIP49 AAA-lid domain GST_N PF02798.20 EWM20279.1 - 0.00079 19.7 0.0 0.0013 19.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EWM20279.1 - 0.046 14.1 0.0 0.08 13.4 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain CTP_synth_N PF06418.14 EWM20281.1 - 7.4e-16 58.3 0.7 9.6e-16 57.9 0.7 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EWM20284.1 - 2.9e-32 112.0 0.0 1.7e-31 109.5 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EWM20284.1 - 0.00084 19.2 0.4 0.19 11.4 0.0 2.2 2 0 0 2 2 2 2 Peptidase C26 K_channel_TID PF07941.11 EWM20284.1 - 4.1 7.9 6.9 12 6.4 0.4 2.7 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain adh_short PF00106.25 EWM20288.1 - 7.4e-10 38.6 0.2 8.8e-10 38.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EWM20288.1 - 0.0022 17.6 0.2 0.0027 17.3 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.8 EWM20288.1 - 0.011 15.5 0.2 0.018 14.8 0.2 1.4 1 1 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2-Hacid_dh_C PF02826.19 EWM20288.1 - 0.019 14.3 0.1 0.023 14.1 0.1 1.3 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DFP PF04127.15 EWM20288.1 - 0.069 13.0 0.2 0.086 12.7 0.2 1.1 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein SpoU_methylase PF00588.19 EWM20290.1 - 1.1e-10 41.8 0.0 3.7e-10 40.1 0.0 1.7 1 1 0 1 1 1 1 SpoU rRNA Methylase family Meth_synt_2 PF01717.18 EWM20293.1 - 3.8e-83 279.4 0.0 5.9e-82 275.5 0.0 2.3 2 0 0 2 2 2 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EWM20293.1 - 1e-66 225.6 0.0 2.3e-64 217.9 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain Aldo_ket_red PF00248.21 EWM20294.1 - 3.1e-12 46.3 0.0 3.7e-12 46.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ion_trans_2 PF07885.16 EWM20296.1 - 3.3e-25 87.8 22.1 1e-13 51.1 8.7 2.3 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 EWM20296.1 - 4.3e-07 29.4 2.8 0.0014 17.9 5.7 2.6 2 1 0 2 2 2 2 Ion transport protein EF-hand_7 PF13499.6 EWM20296.1 - 8.1e-06 26.2 0.4 0.0099 16.3 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EWM20296.1 - 2.5e-05 23.5 0.2 0.19 11.4 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EWM20296.1 - 2.8e-05 23.7 0.0 0.17 11.9 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EWM20296.1 - 0.0014 18.4 0.1 0.55 10.1 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair MFS_1 PF07690.16 EWM20296.1 - 0.013 14.5 6.3 3.2 6.6 6.8 2.1 2 0 0 2 2 2 0 Major Facilitator Superfamily EF-hand_5 PF13202.6 EWM20296.1 - 0.018 14.5 0.1 0.12 11.9 0.1 2.3 2 0 0 2 2 2 0 EF hand Exo84_C PF16528.5 EWM20296.1 - 0.035 13.9 0.0 0.51 10.1 0.0 2.1 2 0 0 2 2 2 0 Exocyst component 84 C-terminal Tetraspanin PF00335.20 EWM20296.1 - 0.049 13.3 0.0 0.13 11.9 0.0 1.6 2 0 0 2 2 2 0 Tetraspanin family FAM176 PF14851.6 EWM20296.1 - 1.3 8.7 8.5 2.8 7.6 4.7 2.4 2 0 0 2 2 2 0 FAM176 family LapA_dom PF06305.11 EWM20296.1 - 2.7 7.8 6.1 0.39 10.6 1.1 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Afi1 PF07792.12 EWM20296.1 - 3.4 8.1 5.6 0.73 10.3 0.6 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Ion_trans_2 PF07885.16 EWM20297.1 - 1.1e-25 89.4 21.1 6.9e-14 51.6 8.5 2.3 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 EWM20297.1 - 2.6e-07 30.1 2.8 0.0014 17.9 6.0 2.4 2 1 0 2 2 2 2 Ion transport protein Tetraspanin PF00335.20 EWM20297.1 - 0.045 13.5 0.0 0.098 12.3 0.0 1.5 1 0 0 1 1 1 0 Tetraspanin family DUF4173 PF13777.6 EWM20297.1 - 0.052 13.0 1.5 0.85 9.0 0.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4173) Exo84_C PF16528.5 EWM20297.1 - 0.13 12.1 0.0 2.2 8.1 0.0 2.0 2 0 0 2 2 2 0 Exocyst component 84 C-terminal FAM176 PF14851.6 EWM20297.1 - 1.1 8.9 8.6 2.3 7.9 4.8 2.3 2 0 0 2 2 2 0 FAM176 family Afi1 PF07792.12 EWM20297.1 - 1.7 9.1 4.9 0.51 10.8 0.5 2.0 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking LapA_dom PF06305.11 EWM20297.1 - 2.5 8.0 6.4 0.32 10.9 1.1 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain RPN2_C PF18004.1 EWM20297.1 - 6.2 6.7 13.6 4 7.4 2.7 2.1 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4215 PF13948.6 EWM20299.1 - 0.031 14.7 3.0 0.065 13.7 3.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4215) PLAC8 PF04749.17 EWM20303.1 - 4.3e-06 27.7 1.4 5.7e-06 27.2 1.4 1.1 1 0 0 1 1 1 1 PLAC8 family p450 PF00067.22 EWM20304.1 - 0.11 11.2 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Cytochrome P450 PHO4 PF01384.20 EWM20309.1 - 9.5e-55 186.0 1.9 1.2e-54 185.7 1.9 1.1 1 0 0 1 1 1 1 Phosphate transporter family DUF4381 PF14316.6 EWM20309.1 - 0.091 13.0 1.5 6.8 6.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Oleosin PF01277.17 EWM20309.1 - 0.12 12.2 1.0 2.6 7.8 0.0 2.7 2 0 0 2 2 2 0 Oleosin LapA_dom PF06305.11 EWM20309.1 - 0.25 11.2 1.3 0.95 9.3 0.1 2.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF2070 PF09843.9 EWM20309.1 - 0.52 8.5 3.4 0.89 7.8 3.4 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ATP-synt_E PF05680.12 EWM20309.1 - 2.5 8.5 6.8 6.7 7.1 0.0 2.5 2 0 0 2 2 2 0 ATP synthase E chain ubiquitin PF00240.23 EWM20311.1 - 9.1e-09 35.0 0.0 2.3e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family L_protein_N PF15518.6 EWM20311.1 - 0.079 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 L protein N-terminus Ubiquitin_2 PF14560.6 EWM20311.1 - 0.11 13.0 0.0 0.27 11.7 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-like domain Glyco_transf_18 PF15024.6 EWM20311.1 - 0.22 10.1 0.0 0.23 10.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 18 Ank_2 PF12796.7 EWM20314.1 - 5.5e-30 103.8 0.0 7.7e-18 64.9 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EWM20314.1 - 1.6e-23 82.0 1.4 5e-07 29.9 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EWM20314.1 - 2.6e-21 75.4 0.3 2.3e-11 43.7 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EWM20314.1 - 1.8e-20 73.0 0.7 1.6e-08 34.9 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EWM20314.1 - 5.2e-18 63.3 1.1 6.8e-06 26.0 0.0 4.4 4 1 0 4 4 4 3 Ankyrin repeat p450 PF00067.22 EWM20316.1 - 9.1e-06 24.7 0.0 1.2e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FANCI_HD2 PF14680.6 EWM20317.1 - 0.053 12.8 0.5 0.087 12.1 0.5 1.3 1 0 0 1 1 1 0 FANCI helical domain 2 Med24_N PF11277.8 EWM20317.1 - 0.2 9.7 0.7 0.29 9.2 0.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal PPP4R2 PF09184.11 EWM20317.1 - 0.23 11.0 8.0 0.4 10.2 8.0 1.3 1 0 0 1 1 1 0 PPP4R2 Afi1 PF07792.12 EWM20317.1 - 0.64 10.5 4.2 1.5 9.3 4.2 1.6 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking TFIIA PF03153.13 EWM20317.1 - 1.5 8.8 11.6 2.6 8.0 11.6 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HNF-1_N PF04814.13 EWM20317.1 - 1.7 9.2 5.1 24 5.5 0.0 3.0 3 0 0 3 3 3 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Pkinase PF00069.25 EWM20318.1 - 0.00035 20.0 0.0 0.0006 19.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM20318.1 - 0.00095 18.5 0.0 0.0021 17.4 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EWM20319.1 - 0.00037 20.0 0.0 0.00062 19.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM20319.1 - 0.001 18.5 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Metallophos_2 PF12850.7 EWM20322.1 - 0.00036 20.8 0.0 0.00049 20.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EWM20322.1 - 0.0006 20.4 0.0 0.00082 19.9 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TrkA_N PF02254.18 EWM20324.1 - 0.15 12.4 0.8 0.23 11.7 0.8 1.2 1 0 0 1 1 1 0 TrkA-N domain BNR PF02012.20 EWM20327.1 - 0.1 12.6 0.3 1.2 9.4 0.2 2.7 2 0 0 2 2 2 0 BNR/Asp-box repeat WD40 PF00400.32 EWM20327.1 - 0.21 12.5 1.5 0.92 10.5 0.3 2.4 2 0 0 2 2 2 0 WD domain, G-beta repeat DUF3128 PF11326.8 EWM20328.1 - 0.086 13.2 0.1 0.2 12.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3128) Myb_DNA-binding PF00249.31 EWM20330.1 - 2.2e-13 50.2 1.7 1.4e-11 44.4 0.2 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EWM20330.1 - 4.3e-11 42.9 0.3 2.1e-05 24.7 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EWM20330.1 - 0.22 11.5 0.0 0.41 10.6 0.0 1.3 1 0 0 1 1 1 0 Myb DNA-binding like AT_hook PF02178.19 EWM20330.1 - 0.59 10.2 15.4 0.37 10.8 4.0 3.0 2 0 0 2 2 2 0 AT hook motif Gpi16 PF04113.14 EWM20336.1 - 1.2e-05 24.0 0.0 2e-05 23.2 0.0 1.3 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component GGACT PF06094.12 EWM20337.1 - 1.1e-15 58.3 0.0 1.3e-15 58.0 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Gpi16 PF04113.14 EWM20338.1 - 5.2e-27 94.5 0.0 5.8e-27 94.4 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component RVT_2 PF07727.14 EWM20343.1 - 8.4e-38 130.4 0.1 9.4e-38 130.2 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.14 EWM20346.1 - 8.8e-67 225.3 0.0 1.7e-66 224.3 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DEDD_Tnp_IS110 PF01548.17 EWM20346.1 - 0.047 13.6 0.1 0.099 12.5 0.1 1.5 1 0 0 1 1 1 0 Transposase zf-AN1 PF01428.16 EWM20355.1 - 5.7e-06 26.4 8.3 8e-06 25.9 8.3 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger DUF2020 PF09449.10 EWM20356.1 - 0.17 11.7 0.0 0.23 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2020) DUF5324 PF17258.2 EWM20357.1 - 0.27 10.9 0.1 0.32 10.7 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5324) Aconitase_C PF00694.19 EWM20360.1 - 0.0025 18.1 0.0 0.0046 17.3 0.0 1.7 1 1 0 1 1 1 1 Aconitase C-terminal domain Acyltransferase PF01553.21 EWM20361.1 - 1.3e-20 73.4 0.0 1.2e-19 70.2 0.0 2.1 2 0 0 2 2 2 1 Acyltransferase MORN PF02493.20 EWM20365.1 - 1.7e-22 77.9 27.6 9e-06 25.3 0.3 8.0 7 1 0 7 7 7 7 MORN repeat DUF3048_C PF17479.2 EWM20365.1 - 0.0014 19.0 3.2 0.29 11.5 0.1 3.1 2 1 1 3 3 3 3 Protein of unknown function (DUF3048) C-terminal domain Glycos_transf_2 PF00535.26 EWM20379.1 - 0.0014 18.4 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 zf-CCHC PF00098.23 EWM20381.1 - 0.00092 19.2 4.5 0.00092 19.2 4.5 2.9 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 EWM20381.1 - 0.14 12.1 11.9 0.069 13.1 3.0 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 EWM20381.1 - 0.27 11.0 5.5 2.1 8.1 0.5 3.5 4 0 0 4 4 4 0 Zinc knuckle zf-CCHC_5 PF14787.6 EWM20381.1 - 0.84 9.4 12.6 1.1 9.1 2.1 2.8 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Retrotran_gag_2 PF14223.6 EWM20382.1 - 5.2e-05 22.9 0.1 8.1e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type PI3K_1B_p101 PF10486.9 EWM20383.1 - 0.012 13.5 6.1 0.015 13.1 6.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Spt20 PF12090.8 EWM20383.1 - 0.27 10.8 11.1 0.46 10.0 11.1 1.3 1 0 0 1 1 1 0 Spt20 family Fmp27 PF10344.9 EWM20383.1 - 0.5 8.4 10.5 0.76 7.8 10.5 1.2 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 AAA_11 PF13086.6 EWM20383.1 - 2.1 8.1 17.7 38 3.9 17.7 2.0 1 1 0 1 1 1 0 AAA domain ALMT PF11744.8 EWM20383.1 - 3.8 6.2 5.7 5 5.8 5.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter MDM10 PF12519.8 EWM20383.1 - 4.2 6.1 6.2 4.5 6.0 6.2 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Peptidase_S49_N PF08496.10 EWM20383.1 - 5.5 7.1 13.1 9.4 6.3 12.1 1.8 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF1764 PF08576.10 EWM20383.1 - 5.9 7.9 20.1 0.74 10.8 10.5 2.9 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF1764) Mpp10 PF04006.12 EWM20383.1 - 6.5 5.1 31.7 1.2 7.5 15.8 2.2 2 1 0 2 2 2 0 Mpp10 protein NOA36 PF06524.12 EWM20383.1 - 7.5 5.8 24.1 5.6 6.2 4.8 2.3 2 0 0 2 2 2 0 NOA36 protein Hid1 PF12722.7 EWM20383.1 - 8.3 4.4 6.7 10 4.1 6.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein G0-G1_switch_2 PF15103.6 EWM20383.1 - 8.8 6.8 12.4 2.4 8.7 8.3 2.1 2 0 0 2 2 2 0 G0/G1 switch protein 2 zf-TAZ PF02135.16 EWM20384.1 - 7.8 7.0 8.4 3.5 8.2 1.8 2.7 1 1 1 2 2 2 0 TAZ zinc finger DUF1428 PF07237.11 EWM20385.1 - 0.074 13.3 0.0 0.086 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) RVT_2 PF07727.14 EWM20386.1 - 3.3e-49 167.7 0.0 4.1e-49 167.4 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-NOSIP PF15906.5 EWM20387.1 - 1.2e-15 57.3 0.0 2.2e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 EWM20387.1 - 1.3e-08 34.6 0.8 0.00042 19.8 0.0 3.3 2 1 1 3 3 3 2 Rtf2 RING-finger U-box PF04564.15 EWM20387.1 - 3.7e-05 23.8 0.1 0.00072 19.7 0.0 2.9 3 0 0 3 3 3 1 U-box domain zf-Nse PF11789.8 EWM20387.1 - 5.4e-05 22.9 0.0 0.0025 17.6 0.0 2.5 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EWM20387.1 - 0.094 12.8 0.0 0.29 11.2 0.0 1.9 1 0 0 1 1 1 0 RING-type zinc-finger DUF853 PF05872.12 EWM20387.1 - 0.17 10.4 0.5 0.25 9.9 0.5 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) ARS2 PF04959.13 EWM20387.1 - 0.21 12.0 1.8 2.5 8.4 0.0 2.6 2 1 0 2 2 2 0 Arsenite-resistance protein 2 Endopep_inhib PF16800.5 EWM20388.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 IseA DL-endopeptidase inhibitor Hormone_6 PF00236.18 EWM20390.1 - 0.0077 16.2 0.2 0.012 15.6 0.2 1.2 1 0 0 1 1 1 1 Glycoprotein hormone KOW PF00467.29 EWM20392.1 - 0.15 12.1 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 KOW motif p450 PF00067.22 EWM20393.1 - 2.1e-34 119.1 0.0 3e-21 75.7 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 EWM20396.1 - 0.19 10.4 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 Cytochrome P450 Macro PF01661.21 EWM20398.1 - 7.3e-14 51.8 0.0 2.1e-13 50.4 0.0 1.8 2 1 0 2 2 2 1 Macro domain Macoilin PF09726.9 EWM20398.1 - 2.7 6.4 5.5 3.8 6.0 5.5 1.1 1 0 0 1 1 1 0 Macoilin family UBA_4 PF14555.6 EWM20399.1 - 8.4e-12 44.7 0.0 1.4e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain SAP PF02037.27 EWM20399.1 - 4.7e-06 26.2 0.3 8.5e-06 25.4 0.3 1.5 1 0 0 1 1 1 1 SAP domain Telomere_Sde2_2 PF13297.6 EWM20399.1 - 0.026 14.2 0.1 0.05 13.2 0.1 1.4 1 0 0 1 1 1 0 Telomere stability C-terminal Arylsulfotran_N PF17425.2 EWM20400.1 - 0.025 14.6 0.0 0.79 9.8 0.0 2.7 2 1 1 3 3 3 0 Arylsulfotransferase Ig-like domain MCR PF18509.1 EWM20400.1 - 0.33 10.5 5.4 2.5 7.8 0.2 3.0 3 0 0 3 3 3 0 Magnetochrome domain Proteasome PF00227.26 EWM20402.1 - 5.5e-15 55.3 0.0 1.2e-07 31.4 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Amidohydro_1 PF01979.20 EWM20404.1 - 0.033 13.5 0.3 0.041 13.2 0.3 1.1 1 0 0 1 1 1 0 Amidohydrolase family MFS_1 PF07690.16 EWM20408.1 - 1.1e-14 54.1 18.6 1.3e-14 53.9 18.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EWM20408.1 - 0.00065 18.7 1.1 0.0011 17.9 0.1 1.7 1 1 1 2 2 2 1 MFS_1 like family MFS_3 PF05977.13 EWM20408.1 - 0.025 13.0 7.4 0.03 12.7 7.4 1.1 1 0 0 1 1 1 0 Transmembrane secretion effector FA_desaturase PF00487.24 EWM20408.1 - 0.92 9.3 5.7 1.4 8.7 5.3 1.6 1 1 1 2 2 2 0 Fatty acid desaturase DUF390 PF04094.14 EWM20411.1 - 0.073 11.4 2.8 0.081 11.2 2.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF390) PHD PF00628.29 EWM20412.1 - 7.6e-07 28.9 1.0 1.4e-06 28.1 1.0 1.4 1 0 0 1 1 1 1 PHD-finger baeRF_family5 PF18846.1 EWM20413.1 - 0.17 12.1 1.0 0.24 11.6 1.0 1.2 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 5 Heme_oxygenase PF01126.20 EWM20414.1 - 6.9e-29 101.1 0.0 8.6e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Heme oxygenase MMR_HSR1 PF01926.23 EWM20415.1 - 2e-16 60.1 0.0 3e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EWM20415.1 - 1.1e-06 28.3 0.0 4.6e-05 23.1 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EWM20415.1 - 0.0005 20.0 0.1 0.21 11.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EWM20415.1 - 0.023 14.2 0.0 0.051 13.1 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B Dynamin_N PF00350.23 EWM20415.1 - 0.089 12.8 0.1 5.3 7.1 0.3 2.2 2 0 0 2 2 2 0 Dynamin family IIGP PF05049.13 EWM20415.1 - 0.099 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) PRIMA1 PF16101.5 EWM20415.1 - 0.42 10.7 5.4 0.78 9.8 5.4 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 zf-CSL PF05207.13 EWM20416.1 - 0.05 13.3 0.0 0.058 13.1 0.0 1.1 1 0 0 1 1 1 0 CSL zinc finger GFO_IDH_MocA PF01408.22 EWM20418.1 - 2.4e-25 89.7 0.6 3.6e-25 89.1 0.6 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EWM20418.1 - 1e-10 41.6 0.0 2e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Sacchrp_dh_NADP PF03435.18 EWM20418.1 - 0.00016 21.9 0.3 0.00046 20.4 0.3 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 EWM20418.1 - 0.00099 19.6 0.1 0.0019 18.7 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_3 PF03447.16 EWM20418.1 - 0.0027 18.3 0.1 0.0042 17.7 0.1 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain NeuB PF03102.14 EWM20418.1 - 0.0032 17.0 0.0 0.0046 16.4 0.0 1.1 1 0 0 1 1 1 1 NeuB family Shikimate_DH PF01488.20 EWM20418.1 - 0.0068 16.5 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 EWM20418.1 - 0.0075 16.5 0.1 0.013 15.8 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain Rossmann-like PF10727.9 EWM20418.1 - 0.029 14.2 0.2 0.11 12.4 0.1 1.9 2 0 0 2 2 2 0 Rossmann-like domain Semialdhyde_dh PF01118.24 EWM20418.1 - 0.038 14.4 0.0 0.072 13.5 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EWM20418.1 - 0.04 13.3 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EWM20418.1 - 0.072 13.5 0.1 0.13 12.7 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding YCII PF03795.14 EWM20419.1 - 1.8e-07 31.4 0.1 3.2e-07 30.6 0.1 1.4 1 1 0 1 1 1 1 YCII-related domain SMC_hinge PF06470.13 EWM20420.1 - 4.3e-10 39.9 0.0 1.2e-09 38.5 0.0 1.8 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain DSBA PF01323.20 EWM20420.1 - 2.3 8.0 10.3 0.061 13.1 1.7 2.6 2 0 0 2 2 2 0 DSBA-like thioredoxin domain Rep_fac_C PF08542.11 EWM20422.1 - 5.4e-20 71.6 0.0 1e-19 70.7 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 EWM20422.1 - 1.8e-14 53.8 0.0 6e-14 52.1 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 EWM20422.1 - 2.5e-11 44.1 0.0 5.6e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EWM20422.1 - 2e-06 28.3 0.0 7.1e-06 26.5 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 EWM20422.1 - 2.1e-05 24.0 0.0 0.00097 18.6 0.0 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 EWM20422.1 - 2.4e-05 24.1 0.0 9.3e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EWM20422.1 - 0.0001 22.6 0.0 0.0015 18.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EWM20422.1 - 0.00016 22.0 0.0 0.0006 20.2 0.0 1.9 1 1 1 2 2 2 1 AAA domain Rad17 PF03215.15 EWM20422.1 - 0.00023 21.1 0.0 0.00045 20.2 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_11 PF13086.6 EWM20422.1 - 0.0011 18.8 0.0 0.0033 17.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EWM20422.1 - 0.0041 16.9 0.0 0.033 13.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain TniB PF05621.11 EWM20422.1 - 0.0091 15.4 0.1 0.58 9.5 0.0 2.5 2 0 0 2 2 2 1 Bacterial TniB protein AAA_5 PF07728.14 EWM20422.1 - 0.015 15.3 0.0 0.92 9.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DEAD PF00270.29 EWM20422.1 - 0.055 13.2 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_25 PF13481.6 EWM20422.1 - 0.068 12.7 0.0 0.26 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 EWM20422.1 - 0.078 12.2 0.0 0.17 11.1 0.0 1.5 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_assoc_2 PF16193.5 EWM20422.1 - 0.11 12.9 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA C-terminal domain FtsK_SpoIIIE PF01580.18 EWM20422.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 EWM20422.1 - 0.17 11.5 0.0 1.4 8.6 0.0 2.2 3 0 0 3 3 3 0 AAA domain PDZ_3 PF17815.1 EWM20423.1 - 1.7e-13 50.7 0.0 3.9e-13 49.5 0.0 1.6 2 0 0 2 2 2 1 PDZ domain Trypsin_2 PF13365.6 EWM20423.1 - 8.7e-09 36.4 0.2 3.9e-08 34.3 0.0 2.1 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_3 PF17815.1 EWM20424.1 - 1.7e-13 50.7 0.0 3.9e-13 49.5 0.0 1.6 2 0 0 2 2 2 1 PDZ domain Trypsin_2 PF13365.6 EWM20424.1 - 8.7e-09 36.4 0.2 3.9e-08 34.3 0.0 2.1 2 0 0 2 2 2 1 Trypsin-like peptidase domain Sad1_UNC PF07738.13 EWM20425.1 - 4.4e-09 36.4 0.0 1.2e-08 35.0 0.0 1.7 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal RD3 PF14473.6 EWM20425.1 - 0.09 12.6 4.8 0.5 10.2 0.2 2.5 2 0 0 2 2 2 0 RD3 protein Choline_transpo PF04515.12 EWM20426.1 - 1.2e-25 90.4 0.1 1.5e-25 90.1 0.1 1.1 1 0 0 1 1 1 1 Plasma-membrane choline transporter Choline_transpo PF04515.12 EWM20427.1 - 7.5e-36 124.0 1.9 8.3e-36 123.8 1.9 1.0 1 0 0 1 1 1 1 Plasma-membrane choline transporter DUF3522 PF12036.8 EWM20427.1 - 0.029 14.6 1.4 0.67 10.2 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3522) MS_channel PF00924.18 EWM20427.1 - 0.71 9.4 4.7 1.1 8.8 4.7 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel DHH PF01368.20 EWM20431.1 - 1e-16 61.0 0.0 1.8e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 DHH family CKS PF01111.19 EWM20432.1 - 1.9e-36 124.1 0.8 2.4e-36 123.8 0.8 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit CKS PF01111.19 EWM20433.1 - 1e-36 125.0 0.8 1.2e-36 124.8 0.8 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit CEND1 PF15677.5 EWM20442.1 - 0.14 12.7 1.8 0.28 11.7 1.8 1.5 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 DHFR_1 PF00186.19 EWM20443.1 - 4e-10 39.6 0.0 6e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Dihydrofolate reductase PPR_3 PF13812.6 EWM20446.1 - 0.0096 16.0 0.0 1.6 8.8 0.0 2.2 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 EWM20446.1 - 0.096 12.9 0.0 3.3 8.0 0.0 2.3 2 0 0 2 2 2 0 PPR repeat family SMP PF04927.12 EWM20448.1 - 6.4 7.3 13.0 1.6 9.3 0.1 3.5 2 1 1 3 3 3 0 Seed maturation protein Metallophos PF00149.28 EWM20450.1 - 1.8e-07 31.9 0.0 2.1e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ssDBP_DBD PF18361.1 EWM20454.1 - 0.073 13.2 0.2 0.086 13.0 0.2 1.2 1 0 0 1 1 1 0 Single stranded DNA-binding protein ss DNA binding domain Sep15_SelM PF08806.11 EWM20456.1 - 5.9e-05 23.2 0.0 8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Sep15/SelM redox domain Peptidase_S10 PF00450.22 EWM20460.1 - 2.4e-15 56.9 0.0 3.3e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.22 EWM20461.1 - 2e-15 57.2 1.2 2.5e-15 56.8 1.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Lipoxygenase PF00305.19 EWM20464.1 - 0.077 11.4 0.2 0.17 10.2 0.2 1.7 1 1 0 1 1 1 0 Lipoxygenase 3-alpha PF03475.14 EWM20465.1 - 0.086 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 3-alpha domain Aminotran_1_2 PF00155.21 EWM20466.1 - 1.8e-10 40.6 0.0 1.7e-08 34.1 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class I and II Methyltransf_21 PF05050.12 EWM20468.1 - 0.00012 22.2 0.1 0.00017 21.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain PI-PLC-C1 PF16670.5 EWM20468.1 - 0.015 14.4 0.0 0.11 11.6 0.0 1.8 1 1 1 2 2 2 0 Phosphoinositide phospholipase C, Ca2+-dependent Serine_protease PF18405.1 EWM20468.1 - 0.044 12.9 0.0 0.05 12.7 0.0 1.1 1 0 0 1 1 1 0 Gammaproteobacterial serine protease rve PF00665.26 EWM20469.1 - 2.6e-18 66.3 0.0 4.1e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 EWM20469.1 - 1e-07 31.7 0.0 1.9e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain RVT_2 PF07727.14 EWM20471.1 - 6e-50 170.1 0.0 7.3e-50 169.9 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 EWM20477.1 - 0.0013 18.7 4.5 0.0013 18.7 4.5 3.0 3 0 0 3 3 3 1 Zinc knuckle eIF3g PF12353.8 EWM20477.1 - 0.12 12.7 0.9 0.12 12.7 0.9 1.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_3 PF13917.6 EWM20477.1 - 0.34 10.9 9.4 0.095 12.7 2.1 2.3 2 0 0 2 2 2 0 Zinc knuckle Cation_ATPase PF13246.6 EWM20479.1 - 1.2e-08 34.9 0.0 1.8e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Cation transport ATPase (P-type) TPP_enzyme_C PF02775.21 EWM20480.1 - 0.17 11.6 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Cation_ATPase_N PF00690.26 EWM20481.1 - 5.5e-14 51.6 0.0 1.1e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cyt_c_ox_IV PF12270.8 EWM20481.1 - 0.058 13.5 0.6 0.09 12.9 0.6 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV PT PF04886.12 EWM20483.1 - 1.8e-45 152.2 180.3 0.0015 18.0 10.9 10.4 1 1 1 2 2 2 1 PT repeat TPT PF03151.16 EWM20484.1 - 8.2e-15 54.9 1.3 1.4e-14 54.2 1.3 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family PT PF04886.12 EWM20486.1 - 7e-21 73.5 100.7 5.6e-06 25.8 30.6 4.1 1 1 3 4 4 4 4 PT repeat ANAPC4_WD40 PF12894.7 EWM20487.1 - 0.079 13.3 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Sulfotransfer_3 PF13469.6 EWM20489.1 - 5.7e-07 30.1 0.0 8.5e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family PSS PF03034.15 EWM20490.1 - 3.6e-71 240.1 14.1 4.6e-71 239.8 14.1 1.1 1 0 0 1 1 1 1 Phosphatidyl serine synthase DUF4834 PF16118.5 EWM20490.1 - 0.099 13.6 0.4 0.28 12.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) PBP1_TM PF14812.6 EWM20490.1 - 5.4 7.5 7.0 15 6.0 7.0 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pollen_Ole_e_I PF01190.17 EWM20491.1 - 0.4 11.1 3.6 0.75 10.2 3.6 1.4 1 0 0 1 1 1 0 Pollen proteins Ole e I like RR_TM4-6 PF06459.12 EWM20491.1 - 1.4 8.7 7.9 3.2 7.5 7.9 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EF_TS PF00889.19 EWM20492.1 - 3.4e-09 36.6 0.0 5.4e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor TS 2OG-FeII_Oxy_3 PF13640.6 EWM20493.1 - 8.4e-17 61.9 0.1 1.4e-16 61.1 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 EWM20493.1 - 1.4e-09 38.5 0.2 8.4e-09 36.0 0.1 2.1 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 EWM20493.1 - 0.14 12.6 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase SR-25 PF10500.9 EWM20494.1 - 0.035 13.7 11.7 0.047 13.3 11.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 EWM20494.1 - 0.081 13.6 5.4 0.14 12.9 5.4 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein IQCJ-SCHIP1 PF15157.6 EWM20494.1 - 0.12 12.2 1.8 0.17 11.7 1.8 1.2 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif DUF755 PF05501.11 EWM20494.1 - 2.6 8.3 13.0 3.7 7.8 13.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Herpes_pp85 PF04637.12 EWM20494.1 - 6.8 5.0 8.1 9.3 4.5 8.1 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Imm72 PF15584.6 EWM20497.1 - 0.054 13.6 0.0 0.073 13.2 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 72 CENP-B_dimeris PF09026.10 EWM20498.1 - 1.7 9.1 6.5 3.2 8.2 6.5 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 EWM20498.1 - 9.8 4.1 7.7 12 3.9 7.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi Methyltransf_23 PF13489.6 EWM20508.1 - 1.2e-07 31.7 0.0 1.7e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM20508.1 - 1.6e-07 31.3 0.0 3.1e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM20508.1 - 2.8e-07 31.2 0.0 5.8e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM20508.1 - 2.2e-05 25.0 0.0 4.4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EWM20508.1 - 0.00013 21.4 0.0 0.00026 20.4 0.0 1.5 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 EWM20508.1 - 0.0034 18.1 0.0 0.0085 16.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EWM20508.1 - 0.0044 17.2 0.0 0.0068 16.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 EWM20508.1 - 0.044 13.5 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Aminotran_1_2 PF00155.21 EWM20510.1 - 0.0013 18.0 0.0 0.12 11.5 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_1_2 PF00155.21 EWM20511.1 - 0.13 11.4 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II Sulfotransfer_2 PF03567.14 EWM20514.1 - 0.0017 18.3 0.0 0.0018 18.3 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family GDP_Man_Dehyd PF16363.5 EWM20515.1 - 1.4e-39 136.5 0.0 1.8e-39 136.1 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EWM20515.1 - 1.5e-36 126.1 0.0 2e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EWM20515.1 - 8.9e-11 41.5 0.0 4.4e-09 35.9 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EWM20515.1 - 2.9e-09 36.3 0.0 3.9e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EWM20515.1 - 2e-07 30.4 0.0 3.7e-07 29.5 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 EWM20515.1 - 6.7e-05 22.9 0.0 0.0001 22.3 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF616 PF04765.13 EWM20516.1 - 1.6e-10 40.7 0.1 2.5e-10 40.1 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF616) GDP_Man_Dehyd PF16363.5 EWM20516.1 - 0.00062 19.3 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase IspD PF01128.19 EWM20517.1 - 0.14 11.9 0.1 0.2 11.4 0.1 1.2 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DEDD_Tnp_IS110 PF01548.17 EWM20518.1 - 0.012 15.5 0.1 0.022 14.6 0.1 1.4 1 0 0 1 1 1 0 Transposase SfsA_N PF17746.1 EWM20521.1 - 0.018 15.2 0.0 0.032 14.4 0.0 1.4 1 0 0 1 1 1 0 SfsA N-terminal OB domain Ank_2 PF12796.7 EWM20522.1 - 1.9e-29 102.1 0.6 4.9e-17 62.3 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EWM20522.1 - 7e-25 86.3 0.1 1.5e-08 34.7 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EWM20522.1 - 6.1e-21 74.5 0.0 1.1e-13 51.4 0.0 3.9 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EWM20522.1 - 1.7e-18 66.4 0.2 3.9e-10 39.8 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EWM20522.1 - 4.7e-16 57.3 1.2 0.0003 21.0 0.0 4.4 5 1 0 5 5 5 3 Ankyrin repeat DUF612 PF04747.12 EWM20522.1 - 0.1 11.7 1.7 0.12 11.4 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF612 Rhomboid PF01694.22 EWM20523.1 - 0.0033 17.4 7.2 0.0033 17.4 7.2 1.7 2 0 0 2 2 2 1 Rhomboid family DUF1751 PF08551.10 EWM20523.1 - 0.15 12.7 3.0 0.22 12.1 2.2 1.7 1 1 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) Carb_anhydrase PF00194.21 EWM20524.1 - 3.1e-15 56.4 0.0 2.6e-14 53.4 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 EWM20525.1 - 9.5e-16 58.1 0.3 1.6e-14 54.0 0.3 2.5 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Peptidase_C2 PF00648.21 EWM20533.1 - 1e-10 41.2 0.0 0.00032 19.8 0.1 2.0 2 0 0 2 2 2 2 Calpain family cysteine protease Apt1 PF10351.9 EWM20536.1 - 0.17 10.7 7.0 0.18 10.6 7.0 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF3558 PF12079.8 EWM20536.1 - 0.28 11.1 11.9 1.3 9.0 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3558) SPX PF03105.19 EWM20536.1 - 0.8 9.6 11.0 0.91 9.4 11.0 1.1 1 0 0 1 1 1 0 SPX domain Secretin_N_2 PF07655.13 EWM20536.1 - 1.8 9.2 16.5 2.7 8.6 4.8 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain Exo_endo_phos PF03372.23 EWM20538.1 - 1.6e-05 24.6 0.0 1.9e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Na_H_Exchanger PF00999.21 EWM20543.1 - 1.1e-07 31.0 3.0 1.4e-07 30.6 3.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family FixQ PF05545.11 EWM20543.1 - 6.4 6.8 0.0 6.4 6.8 0.0 2.5 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ Ribosomal_L4 PF00573.22 EWM20545.1 - 7.3e-38 130.2 4.8 1.1e-37 129.7 4.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Mito_fiss_reg PF05308.11 EWM20545.1 - 0.077 13.1 3.0 0.14 12.3 3.0 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EWM20545.1 - 0.17 11.4 5.7 0.26 10.7 5.7 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF4653 PF15546.6 EWM20545.1 - 0.29 10.7 3.8 0.45 10.1 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) Dscam_C PF12355.8 EWM20545.1 - 0.37 11.8 5.9 0.81 10.7 5.9 1.5 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal PRIMA1 PF16101.5 EWM20545.1 - 0.69 10.0 8.1 1.5 8.8 8.1 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Macoilin PF09726.9 EWM20546.1 - 0.18 10.3 3.5 0.14 10.7 2.1 1.5 1 1 0 1 1 1 0 Macoilin family SURF1 PF02104.15 EWM20548.1 - 3.3e-13 50.3 0.0 4.4e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 SURF1 family Peptidase_M3 PF01432.20 EWM20550.1 - 4.6e-11 42.7 0.0 4.9e-11 42.6 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M3 Glyco_hydro_9 PF00759.19 EWM20555.1 - 1.4e-126 423.3 15.5 1.6e-126 423.1 15.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Glyco_hydro_127 PF07944.12 EWM20555.1 - 0.1 11.1 0.0 0.45 9.0 0.0 1.8 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 Longin PF13774.6 EWM20557.1 - 2.2e-19 69.3 0.0 3e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Regulated-SNARE-like domain 2OG-FeII_Oxy PF03171.20 EWM20558.1 - 1.1e-18 67.6 0.0 1.4e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Synaptobrevin PF00957.21 EWM20559.1 - 0.0028 17.4 0.0 0.004 16.9 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Pox_A14 PF05767.12 EWM20559.1 - 0.096 12.9 0.1 0.36 11.0 0.1 1.8 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 DIOX_N PF14226.6 EWM20560.1 - 1.6e-17 64.3 0.0 2.2e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Corona_NS8 PF12093.8 EWM20562.1 - 0.054 14.1 0.0 0.067 13.8 0.0 1.1 1 0 0 1 1 1 0 Coronavirus NS8 protein 1-cysPrx_C PF10417.9 EWM20562.1 - 0.12 12.2 0.7 0.27 11.1 0.2 1.7 2 0 0 2 2 2 0 C-terminal domain of 1-Cys peroxiredoxin PX PF00787.24 EWM20563.1 - 0.014 15.4 0.5 0.018 15.0 0.5 1.3 1 1 0 1 1 1 0 PX domain GAS PF13851.6 EWM20563.1 - 0.023 14.1 8.7 0.023 14.0 8.7 1.0 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding IFT57 PF10498.9 EWM20563.1 - 0.034 13.1 3.7 0.037 13.0 3.7 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 RTBV_P46 PF06216.11 EWM20563.1 - 0.095 11.6 0.6 0.1 11.5 0.6 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein YabA PF06156.13 EWM20563.1 - 0.28 11.8 4.7 0.67 10.6 4.7 1.7 1 1 0 1 1 1 0 Initiation control protein YabA TMF_DNA_bd PF12329.8 EWM20563.1 - 0.36 10.9 8.5 0.73 9.9 8.3 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding MCC-bdg_PDZ PF10506.9 EWM20563.1 - 0.36 10.9 6.0 0.48 10.5 1.8 2.0 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Cep57_CLD_2 PF14197.6 EWM20563.1 - 0.74 10.0 10.4 0.86 9.7 10.4 1.1 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Snurportin1 PF11538.8 EWM20563.1 - 4.1 7.7 8.7 6.6 7.0 0.1 2.3 2 0 0 2 2 2 0 Snurportin1 Maf1 PF09174.10 EWM20564.1 - 0.03 14.5 0.0 0.04 14.1 0.0 1.2 1 0 0 1 1 1 0 Maf1 regulator CobW_C PF07683.14 EWM20566.1 - 1.7e-20 72.7 0.6 1.6e-19 69.6 0.6 2.4 1 1 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain DUF1153 PF06627.11 EWM20566.1 - 0.13 12.5 0.5 0.34 11.1 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1153) MCM_N PF14551.6 EWM20572.1 - 2e-05 25.1 0.0 3.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 MCM N-terminal domain Oxidored_molyb PF00174.19 EWM20573.1 - 1.9e-57 193.6 0.0 4e-57 192.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EWM20573.1 - 1.4e-47 161.2 0.1 2.3e-47 160.5 0.1 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 EWM20573.1 - 1.5e-20 73.1 0.0 3.1e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NIR_SIR PF01077.22 EWM20575.1 - 3.2e-38 130.7 0.0 6.8e-38 129.7 0.0 1.5 2 0 0 2 2 2 1 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 EWM20575.1 - 1.2e-16 60.3 0.1 2.3e-16 59.4 0.1 1.5 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain PCYCGC PF13798.6 EWM20577.1 - 0.045 13.6 0.3 0.087 12.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function with PCYCGC motif Mrr_cat PF04471.12 EWM20577.1 - 0.15 12.1 0.0 0.34 10.9 0.0 1.5 2 0 0 2 2 2 0 Restriction endonuclease MMR_HSR1 PF01926.23 EWM20578.1 - 1.3e-10 41.3 0.0 1.8e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP1_OBG PF01018.22 EWM20578.1 - 2.6e-07 30.4 0.1 3.8e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 GTP1/OBG FeoB_N PF02421.18 EWM20578.1 - 3.5e-05 23.4 0.0 4.6e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 EWM20578.1 - 0.092 13.3 0.0 0.14 12.7 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 EWM20578.1 - 0.21 11.8 0.0 0.33 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain ECR1_N PF14382.6 EWM20579.1 - 4.6e-06 26.3 0.3 4.1e-05 23.3 0.3 2.4 1 1 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Ins134_P3_kin PF05770.11 EWM20582.1 - 0.00015 21.4 0.0 0.0012 18.4 0.0 1.9 1 1 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain FAM75 PF14650.6 EWM20582.1 - 3.7 7.0 6.6 5.5 6.4 6.6 1.3 1 0 0 1 1 1 0 FAM75 family zf-RING_2 PF13639.6 EWM20583.1 - 3.3e-11 43.3 9.5 5.1e-11 42.7 9.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EWM20583.1 - 1.2e-09 37.7 4.5 2.2e-09 36.9 4.5 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 EWM20583.1 - 3.3e-07 30.2 7.2 5e-07 29.6 7.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EWM20583.1 - 3.3e-07 30.0 9.2 5.1e-07 29.4 9.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EWM20583.1 - 9.5e-07 29.0 8.4 1.6e-06 28.3 8.4 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EWM20583.1 - 6.7e-06 25.9 7.6 1e-05 25.3 7.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EWM20583.1 - 0.00025 21.0 7.5 0.00053 20.0 7.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EWM20583.1 - 0.001 18.9 8.7 0.0018 18.1 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EWM20583.1 - 0.0075 16.1 6.7 0.0076 16.1 5.8 1.4 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EWM20583.1 - 0.0088 16.1 2.9 0.017 15.2 2.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EWM20583.1 - 0.087 12.5 7.2 0.14 11.8 7.2 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zinc_ribbon_16 PF17034.5 EWM20583.1 - 0.12 12.6 2.4 0.2 11.9 2.4 1.4 1 0 0 1 1 1 0 Zinc-ribbon like family PHD PF00628.29 EWM20583.1 - 0.54 10.2 8.3 0.92 9.5 8.3 1.4 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.7 EWM20583.1 - 0.79 9.9 7.6 1.7 8.9 7.6 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 EWM20583.1 - 9.4 6.6 10.3 0.34 11.3 3.8 1.8 2 0 0 2 2 2 0 RING-like domain Thaumatin PF00314.17 EWM20584.1 - 0.12 12.0 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 Thaumatin family Enterotoxin_HS1 PF08090.11 EWM20584.1 - 0.12 12.3 0.6 0.12 12.3 0.6 2.1 2 0 0 2 2 2 0 Heat stable E.coli enterotoxin 1 CorA PF01544.18 EWM20585.1 - 5.9e-06 25.8 0.8 6.7e-06 25.6 0.8 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ATPgrasp_ST PF14397.6 EWM20586.1 - 5.3e-08 32.5 0.0 9.3e-07 28.4 0.0 2.7 2 2 1 3 3 3 1 Sugar-transfer associated ATP-grasp AMP-binding PF00501.28 EWM20588.1 - 1.1e-92 310.8 0.0 1.4e-92 310.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EWM20588.1 - 1.4e-06 29.2 0.1 4.5e-06 27.5 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ribosomal_L7Ae PF01248.26 EWM20590.1 - 9e-22 76.6 0.0 1.2e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DPBB_1 PF03330.18 EWM20590.1 - 0.034 14.4 0.0 10 6.5 0.0 2.2 2 0 0 2 2 2 0 Lytic transglycolase CSRNP_N PF16019.5 EWM20590.1 - 0.095 12.6 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus CN_hydrolase PF00795.22 EWM20591.1 - 3.7e-57 193.6 0.0 4.4e-57 193.4 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Fe_hyd_lg_C PF02906.14 EWM20592.1 - 9.2e-33 113.9 0.0 1.7e-31 109.8 0.0 2.3 2 1 0 2 2 2 1 Iron only hydrogenase large subunit, C-terminal domain Vta1 PF04652.16 EWM20593.1 - 1.1e-17 64.4 0.0 1.3e-17 64.1 0.0 1.0 1 0 0 1 1 1 1 Vta1 like Methyltransf_28 PF02636.17 EWM20594.1 - 5.5e-17 62.3 0.0 8.8e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PET117 PF15786.5 EWM20595.1 - 9.2e-07 29.0 0.2 1.2e-06 28.7 0.2 1.1 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial PAP_PilO PF06864.12 EWM20595.1 - 0.052 12.4 0.1 0.061 12.2 0.1 1.0 1 0 0 1 1 1 0 Pilin accessory protein (PilO) Mif2_N PF15624.6 EWM20596.1 - 0.012 16.4 0.2 0.014 16.1 0.2 1.0 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal HpcH_HpaI PF03328.14 EWM20597.1 - 2.3e-21 76.0 0.0 3e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.18 EWM20597.1 - 0.00016 20.9 0.0 0.00019 20.7 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain C-C_Bond_Lyase PF15617.6 EWM20597.1 - 0.028 13.6 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 C-C_Bond_Lyase of the TIM-Barrel fold Aminotran_3 PF00202.21 EWM20598.1 - 1.5e-112 376.3 0.0 1.7e-112 376.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III BATS PF06968.13 EWM20601.1 - 3.8e-14 52.6 0.1 5.5e-14 52.1 0.1 1.2 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain RRM_1 PF00076.22 EWM20603.1 - 2.3e-15 56.2 0.1 3.1e-15 55.7 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EWM20603.1 - 1.4e-06 27.9 0.0 2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EWM20603.1 - 0.032 14.3 0.1 0.058 13.4 0.1 1.4 1 0 0 1 1 1 0 RNA binding motif Limkain-b1 PF11608.8 EWM20603.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 PP2C PF00481.21 EWM20604.1 - 2e-19 70.2 0.0 9.9e-19 68.0 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EWM20604.1 - 0.077 12.9 0.0 0.098 12.6 0.0 1.2 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) Pkinase PF00069.25 EWM20605.1 - 1.7e-20 73.5 0.0 2e-20 73.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM20605.1 - 1.7e-05 24.3 0.0 2.1e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EWM20605.1 - 0.002 17.5 0.0 0.0031 16.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 EWM20610.1 - 1.1e-08 34.8 0.0 1.2e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosomal_60s PF00428.19 EWM20611.1 - 0.023 15.3 5.4 0.035 14.7 3.5 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF1180 PF06679.12 EWM20612.1 - 0.48 10.8 2.6 0.23 11.8 0.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) ApbA_C PF08546.11 EWM20614.1 - 1.3e-14 54.5 0.0 5.7e-14 52.4 0.0 1.8 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EWM20619.1 - 1.9e-07 30.8 0.0 2.6e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA RskA PF10099.9 EWM20619.1 - 0.0013 19.1 0.3 0.0016 18.7 0.3 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA NAD_binding_8 PF13450.6 EWM20619.1 - 0.0014 18.9 0.0 0.0021 18.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EWM20619.1 - 0.0051 16.4 0.0 0.0067 16.1 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Glu_dehyd_C PF16912.5 EWM20619.1 - 0.0054 16.2 0.0 0.0075 15.8 0.0 1.1 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Shikimate_DH PF01488.20 EWM20619.1 - 0.0098 16.0 0.0 0.014 15.5 0.0 1.1 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 EWM20619.1 - 0.01 16.4 0.0 0.014 15.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 EWM20619.1 - 0.08 12.3 0.0 0.099 12.0 0.0 1.1 1 0 0 1 1 1 0 GMC oxidoreductase Pyr_redox_2 PF07992.14 EWM20619.1 - 0.082 12.1 0.0 0.099 11.8 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase KR PF08659.10 EWM20619.1 - 0.16 11.9 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 KR domain Sugar_tr PF00083.24 EWM20620.1 - 1.3e-15 57.3 8.9 1.7e-15 56.9 8.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter TssN PF17555.2 EWM20620.1 - 0.064 12.6 2.9 0.1 12.0 2.5 1.5 1 1 0 1 1 1 0 Type VI secretion system, TssN MFS_1 PF07690.16 EWM20620.1 - 0.72 8.7 16.6 0.052 12.5 8.1 1.7 1 1 0 1 1 1 0 Major Facilitator Superfamily DUF3487 PF11990.8 EWM20620.1 - 2.9 7.8 5.4 1.7 8.6 2.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) ABC2_membrane_2 PF12679.7 EWM20620.1 - 9.4 5.4 11.4 13 5.0 11.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF3586 PF12131.8 EWM20623.1 - 0.0011 19.2 0.1 0.0098 16.1 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3586) CX PF01705.19 EWM20625.1 - 0.049 14.2 0.0 0.099 13.2 0.0 1.5 1 0 0 1 1 1 0 CX module OppC_N PF12911.7 EWM20629.1 - 0.024 14.6 0.1 0.076 13.0 0.1 1.8 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF5463 PF17551.2 EWM20629.1 - 0.031 14.2 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5463) DUF1180 PF06679.12 EWM20629.1 - 1.1 9.7 4.3 2.3 8.6 4.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Pheromone PF08015.11 EWM20630.1 - 5.6 8.1 9.6 0.66 11.1 1.6 2.6 2 0 0 2 2 2 0 Fungal mating-type pheromone ArfGap PF01412.18 EWM20631.1 - 5.5e-31 107.1 0.1 7.4e-31 106.7 0.1 1.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Proteasome PF00227.26 EWM20632.1 - 5.1e-43 146.8 0.0 8.1e-43 146.1 0.0 1.3 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EWM20632.1 - 5.6e-12 45.1 0.1 9.2e-12 44.4 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature uDENN PF03456.18 EWM20633.1 - 6.3e-13 49.3 0.3 6.3e-13 49.3 0.3 3.2 4 0 0 4 4 4 1 uDENN domain DENN PF02141.21 EWM20633.1 - 0.0087 16.0 0.5 1.2 9.1 0.0 2.3 2 0 0 2 2 2 2 DENN (AEX-3) domain UPF0176_N PF17773.1 EWM20635.1 - 1.2e-06 28.8 0.0 1.4e-05 25.3 0.0 2.0 2 0 0 2 2 2 1 UPF0176 acylphosphatase like domain Redoxin PF08534.10 EWM20636.1 - 0.00052 19.8 0.3 0.00091 19.0 0.1 1.5 2 0 0 2 2 2 1 Redoxin Rhodanese_C PF12368.8 EWM20637.1 - 3.1e-11 43.5 9.1 3.3e-06 27.4 8.3 2.7 2 1 0 2 2 2 2 Rhodanase C-terminal FYVE_2 PF02318.16 EWM20637.1 - 0.0049 17.1 4.4 0.0077 16.4 4.4 1.2 1 0 0 1 1 1 1 FYVE-type zinc finger Rhodanese PF00581.20 EWM20637.1 - 0.056 14.0 0.1 0.088 13.3 0.1 1.3 1 0 0 1 1 1 0 Rhodanese-like domain zinc-ribbons_6 PF07191.12 EWM20637.1 - 0.13 12.3 7.7 0.37 10.8 7.7 1.8 1 1 0 1 1 1 0 zinc-ribbons FYVE PF01363.21 EWM20637.1 - 0.38 10.9 9.3 0.92 9.7 9.3 1.7 1 1 0 1 1 1 0 FYVE zinc finger zf-piccolo PF05715.13 EWM20637.1 - 2.4 8.4 7.8 6.3 7.0 7.8 1.7 1 1 0 1 1 1 0 Piccolo Zn-finger SR-25 PF10500.9 EWM20638.1 - 2.6 7.6 4.6 1.6 8.3 0.2 2.0 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein MA3 PF02847.17 EWM20639.1 - 3.8e-25 88.0 2.0 7e-25 87.2 2.0 1.5 1 0 0 1 1 1 1 MA3 domain DUF5523 PF17661.1 EWM20639.1 - 0.00071 19.3 1.5 0.00071 19.3 1.5 1.9 2 0 0 2 2 2 1 Family of unknown function (DUF5523) FAM199X PF15814.5 EWM20639.1 - 0.01 14.9 17.0 0.017 14.2 17.0 1.3 1 0 0 1 1 1 0 Protein family FAM199X CCDC24 PF15669.5 EWM20639.1 - 0.02 14.8 4.7 0.044 13.6 4.7 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family SARAF PF06682.12 EWM20639.1 - 1.2 8.7 9.2 2.4 7.7 9.2 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Apt1 PF10351.9 EWM20639.1 - 5.7 5.7 20.6 0.32 9.8 15.2 1.6 2 0 0 2 2 2 0 Golgi-body localisation protein domain Striatin PF08232.12 EWM20639.1 - 7.6 7.1 10.2 7.8 7.1 6.4 2.3 2 0 0 2 2 2 0 Striatin family rRNA_processing PF08524.11 EWM20639.1 - 8.4 6.4 7.2 18 5.3 1.7 2.5 2 0 0 2 2 2 0 rRNA processing SSP160 PF06933.11 EWM20639.1 - 9.4 4.3 25.8 11 4.0 25.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DEAD PF00270.29 EWM20640.1 - 1.9e-41 141.8 0.1 2.6e-41 141.3 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EWM20640.1 - 2.5e-28 98.6 1.4 2.3e-27 95.6 0.4 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EWM20640.1 - 5.4e-05 23.2 0.0 9.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EWM20640.1 - 0.005 16.1 0.1 0.0075 15.5 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 EWM20640.1 - 0.011 15.1 0.8 0.017 14.5 0.2 1.6 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Aldedh PF00171.22 EWM20640.1 - 0.16 10.4 0.2 0.24 9.9 0.2 1.1 1 0 0 1 1 1 0 Aldehyde dehydrogenase family Bestrophin PF01062.21 EWM20641.1 - 9.5e-07 28.5 0.0 1.2e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Mito_fiss_reg PF05308.11 EWM20642.1 - 0.11 12.6 2.7 0.17 12.0 2.7 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator PRIMA1 PF16101.5 EWM20642.1 - 2.6 8.1 18.5 1.9 8.5 16.8 1.6 1 1 0 1 1 1 0 Proline-rich membrane anchor 1 WGG PF10273.9 EWM20644.1 - 2.1e-20 73.1 0.0 3.4e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Thioredoxin PF00085.20 EWM20645.1 - 1.8e-14 53.6 0.0 2.3e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 EWM20645.1 - 3.5e-05 23.9 0.0 6.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 EWM20645.1 - 0.00072 19.8 0.0 0.0012 19.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EWM20645.1 - 0.0052 17.2 0.0 0.0074 16.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EWM20645.1 - 0.011 15.1 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EWM20645.1 - 0.047 13.6 0.0 0.07 13.0 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family DUF2847 PF11009.8 EWM20645.1 - 0.076 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) Bestrophin PF01062.21 EWM20646.1 - 6e-13 48.8 0.6 8.9e-13 48.3 0.6 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel RRM_2 PF04059.12 EWM20646.1 - 0.085 13.1 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif 2 BofA PF07441.11 EWM20646.1 - 0.43 10.8 3.8 1 9.6 3.9 1.5 1 1 0 1 1 1 0 SigmaK-factor processing regulatory protein BofA ATP-synt_J PF04911.12 EWM20646.1 - 2.7 7.7 3.6 3.7 7.2 0.0 2.7 3 0 0 3 3 3 0 ATP synthase j chain Glyco_transf_17 PF04724.13 EWM20648.1 - 2.2e-17 63.1 0.0 3.2e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 17 Glyco_transf_10 PF00852.19 EWM20649.1 - 3.8e-32 111.4 0.1 6.4e-32 110.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 EWM20649.1 - 1.2e-08 35.4 0.0 1.5e-07 31.9 0.0 2.4 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal DUF1640 PF07798.11 EWM20651.1 - 0.00013 22.0 5.6 0.00033 20.8 5.6 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) DUF1664 PF07889.12 EWM20651.1 - 0.11 12.6 1.8 0.21 11.6 1.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Peroxidase_2 PF01328.17 EWM20651.1 - 0.11 13.0 0.2 0.16 12.5 0.2 1.2 1 0 0 1 1 1 0 Peroxidase, family 2 ETS_PEA3_N PF04621.13 EWM20651.1 - 1.7 8.5 4.8 2.1 8.1 4.7 1.3 1 1 0 1 1 1 0 PEA3 subfamily ETS-domain transcription factor N terminal domain Siah-Interact_N PF09032.11 EWM20651.1 - 7.5 6.9 6.6 1.5 9.2 1.2 2.3 2 0 0 2 2 2 0 Siah interacting protein, N terminal CopD PF05425.13 EWM20652.1 - 0.0031 17.9 0.0 0.0048 17.3 0.0 1.3 1 0 0 1 1 1 1 Copper resistance protein D PepSY_TM PF03929.16 EWM20652.1 - 0.12 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 PepSY-associated TM region DUF4635 PF15466.6 EWM20652.1 - 0.13 11.8 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) E1-N PF14463.6 EWM20653.1 - 0.15 11.9 1.3 1.9 8.3 0.2 2.1 2 0 0 2 2 2 0 E1 N-terminal domain ERM PF00769.19 EWM20653.1 - 3 7.6 11.7 0.58 9.9 8.0 1.6 2 0 0 2 2 2 0 Ezrin/radixin/moesin family PQQ_3 PF13570.6 EWM20654.1 - 0.051 14.1 19.7 2.9 8.5 0.2 6.2 7 0 0 7 7 7 0 PQQ-like domain adh_short_C2 PF13561.6 EWM20657.1 - 7.5e-52 176.2 0.5 1e-51 175.8 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EWM20657.1 - 7.1e-45 152.9 0.9 9.7e-45 152.4 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EWM20657.1 - 5e-12 46.1 0.1 7.6e-12 45.5 0.1 1.2 1 0 0 1 1 1 1 KR domain HATPase_c PF02518.26 EWM20657.1 - 0.025 15.1 0.0 0.049 14.1 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 3Beta_HSD PF01073.19 EWM20657.1 - 0.058 12.4 0.1 0.079 12.0 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EWM20657.1 - 0.093 12.2 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EWM20657.1 - 0.11 11.7 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DnaJ_C PF01556.18 EWM20659.1 - 9.2e-36 123.2 0.1 1.3e-35 122.7 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EWM20659.1 - 4e-27 94.1 1.5 6.4e-27 93.5 1.5 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EWM20659.1 - 2.4e-13 50.2 19.2 5e-13 49.2 19.2 1.6 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EWM20659.1 - 4.6e-06 26.5 15.0 0.0032 17.4 2.9 2.7 2 1 1 3 3 3 2 Tryptophan RNA-binding attenuator protein inhibitory protein zf-RING_10 PF16685.5 EWM20659.1 - 0.19 11.9 3.8 0.22 11.7 0.1 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 Sigma70_r4 PF04545.16 EWM20659.1 - 0.2 11.2 1.0 0.43 10.1 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 His_Phos_1 PF00300.22 EWM20660.1 - 1.1e-15 57.8 0.4 1.1e-08 35.1 0.1 3.0 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) zf-Tim10_DDP PF02953.15 EWM20661.1 - 3.6e-18 65.0 0.1 5e-18 64.5 0.1 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Topoisom_bac PF01131.20 EWM20663.1 - 1.1e-107 360.6 0.0 1.4e-107 360.3 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 EWM20663.1 - 2.5e-11 43.7 0.0 4.7e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Toprim domain FoP_duplication PF13865.6 EWM20663.1 - 5.4 7.6 7.3 10 6.7 7.3 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Popeye PF04831.13 EWM20664.1 - 8.8e-12 45.4 0.0 1.3e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Popeye protein conserved region cNMP_binding PF00027.29 EWM20664.1 - 1.3e-05 25.2 0.0 0.00014 21.9 0.0 2.6 2 1 0 2 2 2 1 Cyclic nucleotide-binding domain Mito_carr PF00153.27 EWM20665.1 - 2.6e-41 139.5 1.8 3.6e-16 58.8 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Neisseria_TspB PF05616.13 EWM20665.1 - 3.2 6.1 9.0 5.6 5.3 8.3 1.6 2 0 0 2 2 2 0 Neisseria meningitidis TspB protein Mito_carr PF00153.27 EWM20666.1 - 2.7e-41 139.4 1.8 3.6e-16 58.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Neisseria_TspB PF05616.13 EWM20666.1 - 3.2 6.1 9.0 5.6 5.3 8.3 1.6 2 0 0 2 2 2 0 Neisseria meningitidis TspB protein ABC2_membrane PF01061.24 EWM20670.1 - 2e-24 86.2 17.1 3.3e-24 85.5 17.1 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 EWM20670.1 - 6.1e-05 22.3 16.0 9.7e-05 21.6 16.0 1.3 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 EWM20670.1 - 9e-05 21.9 9.8 0.00011 21.6 9.8 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein PDR_CDR PF06422.12 EWM20670.1 - 0.0017 18.2 0.0 0.0017 18.2 0.0 2.8 3 1 0 3 3 3 1 CDR ABC transporter RAP1 PF07218.11 EWM20671.1 - 1.5 7.1 3.2 1.6 6.9 3.2 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) STIMATE PF12400.8 EWM20672.1 - 9.7e-27 94.0 1.5 3.3e-26 92.3 1.5 1.8 1 1 0 1 1 1 1 STIMATE family ThiW PF09512.10 EWM20672.1 - 0.056 13.6 0.3 0.056 13.6 0.3 1.8 2 0 0 2 2 2 0 Thiamine-precursor transporter protein (ThiW) BAG PF02179.16 EWM20674.1 - 0.00055 20.3 0.3 0.00055 20.3 0.3 2.0 2 0 0 2 2 2 1 BAG domain Gon7 PF08738.10 EWM20674.1 - 0.16 12.1 6.1 3.4 7.8 1.1 2.6 3 0 0 3 3 3 0 Gon7 family Folliculin PF11704.8 EWM20674.1 - 0.55 10.1 5.4 0.96 9.3 5.3 1.7 1 1 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF2205 PF10224.9 EWM20674.1 - 4.1 7.5 11.0 3.2 7.8 0.6 3.1 3 0 0 3 3 3 0 Short coiled-coil protein PhoLip_ATPase_C PF16212.5 EWM20676.1 - 4.2e-22 79.1 5.7 5.7e-22 78.7 5.7 1.1 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 EWM20676.1 - 1.9e-10 41.4 0.0 2.8e-05 24.5 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EWM20676.1 - 0.0027 17.5 1.1 0.0085 15.9 0.1 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase ATPase PF06745.13 EWM20676.1 - 0.15 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 KaiC C2 PF00168.30 EWM20678.1 - 1e-06 29.0 0.0 1.6e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 C2 domain RNase_PH PF01138.21 EWM20680.1 - 3.1e-18 66.6 0.0 4.6e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EWM20680.1 - 2.6e-05 24.1 0.0 6.4e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 adh_short PF00106.25 EWM20681.1 - 9.5e-31 106.8 0.0 6.8e-28 97.5 0.0 2.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EWM20681.1 - 1.7e-16 60.5 0.0 1.9e-13 50.5 0.0 3.6 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM20681.1 - 4.7e-06 26.6 0.0 9.3e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EWM20681.1 - 0.027 13.9 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1180 PF06679.12 EWM20682.1 - 0.18 12.2 0.1 0.18 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF1764 PF08576.10 EWM20684.1 - 3e-17 63.4 0.0 3e-17 63.4 0.0 2.0 1 1 1 2 2 2 1 Eukaryotic protein of unknown function (DUF1764) zf-UBP PF02148.19 EWM20686.1 - 4.4e-16 59.0 7.4 1.2e-15 57.5 7.4 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein BRAP2 PF07576.12 EWM20686.1 - 1.9e-11 44.0 0.0 3e-09 37.0 0.0 2.8 3 0 0 3 3 3 1 BRCA1-associated protein 2 zf-RING_5 PF14634.6 EWM20686.1 - 5.6e-05 23.0 0.8 5.6e-05 23.0 0.8 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 EWM20686.1 - 0.0011 19.2 1.9 0.0011 19.2 1.9 2.1 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EWM20686.1 - 0.01 16.2 6.5 0.01 16.2 6.5 2.5 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EWM20686.1 - 0.012 15.5 3.5 0.012 15.5 3.5 2.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EWM20686.1 - 0.017 14.9 4.7 0.054 13.3 1.1 2.7 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4 PF00097.25 EWM20686.1 - 0.029 14.2 3.1 0.11 12.3 3.3 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HAUS-augmin3 PF14932.6 EWM20686.1 - 0.072 12.7 4.5 0.13 11.8 4.5 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 OrfB_Zn_ribbon PF07282.11 EWM20686.1 - 0.29 11.1 2.4 0.45 10.5 0.6 2.3 2 0 0 2 2 2 0 Putative transposase DNA-binding domain SOAR PF16533.5 EWM20686.1 - 0.62 10.1 4.3 3.7 7.6 4.7 1.9 1 1 1 2 2 2 0 STIM1 Orai1-activating region Spc7 PF08317.11 EWM20686.1 - 0.7 8.7 7.5 0.97 8.2 7.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 EWM20686.1 - 1.9 8.6 9.3 3.9 7.5 8.9 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 EWM20686.1 - 2.9 8.1 12.0 2.5 8.3 2.1 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Apolipoprotein PF01442.18 EWM20686.1 - 4.8 7.0 14.6 19 5.0 14.6 1.9 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain FAM184 PF15665.5 EWM20686.1 - 9.2 6.0 10.0 15 5.3 10.0 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B zf-RING_UBOX PF13445.6 EWM20686.1 - 9.2 6.4 8.9 1.5 8.9 4.1 2.1 1 1 1 2 2 2 0 RING-type zinc-finger RVT_2 PF07727.14 EWM20690.1 - 1.8e-66 224.3 0.0 3.2e-66 223.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 EWM20690.1 - 0.0063 16.5 4.5 0.0063 16.5 4.5 3.1 2 0 0 2 2 2 1 Zinc knuckle DEDD_Tnp_IS110 PF01548.17 EWM20690.1 - 0.028 14.3 0.2 0.058 13.3 0.2 1.5 1 0 0 1 1 1 0 Transposase eIF3g PF12353.8 EWM20690.1 - 0.18 12.2 0.9 0.59 10.5 0.9 1.9 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_3 PF13917.6 EWM20690.1 - 0.64 10.0 9.3 0.92 9.5 2.9 2.7 2 0 0 2 2 2 0 Zinc knuckle NTPase_I-T PF01931.18 EWM20694.1 - 1.1e-42 145.6 0.0 2.9e-26 92.2 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function DUF84 Thioredoxin PF00085.20 EWM20695.1 - 6.7e-05 22.8 0.0 9.9e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin WD40 PF00400.32 EWM20698.1 - 7.5e-10 39.3 7.0 0.00022 22.0 1.6 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM20698.1 - 0.00068 19.9 0.0 0.0027 17.9 0.0 1.9 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Ferritin PF00210.24 EWM20700.1 - 1.6e-19 70.3 0.1 2e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 Ferritin-like domain Rubrerythrin PF02915.17 EWM20700.1 - 0.0013 19.1 0.4 0.003 17.9 0.0 1.7 2 0 0 2 2 2 1 Rubrerythrin EVI2A PF05399.11 EWM20700.1 - 1.2 8.7 4.5 5.4 6.5 0.1 2.5 3 0 0 3 3 3 0 Ectropic viral integration site 2A protein (EVI2A) Mucin PF01456.17 EWM20702.1 - 0.11 12.5 5.7 0.4 10.7 5.7 1.9 1 1 0 1 1 1 0 Mucin-like glycoprotein DUF3584 PF12128.8 EWM20702.1 - 0.92 6.9 12.5 1 6.8 12.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) WTX PF09422.10 EWM20702.1 - 8.3 5.4 17.1 11 4.9 17.1 1.2 1 0 0 1 1 1 0 WTX protein DUF2752 PF10825.8 EWM20703.1 - 0.039 14.0 0.0 0.096 12.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) NSs PF11073.8 EWM20703.1 - 0.048 13.1 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 Rift valley fever virus non structural protein (NSs) like ATP_bind_3 PF01171.20 EWM20706.1 - 2.9e-19 69.5 0.0 3.5e-19 69.3 0.0 1.0 1 0 0 1 1 1 1 PP-loop family QueC PF06508.13 EWM20706.1 - 0.026 14.0 0.0 0.18 11.3 0.0 1.9 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Lar_restr_allev PF14354.6 EWM20707.1 - 0.039 14.3 0.0 0.082 13.3 0.0 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar Mitoc_mL59 PF18126.1 EWM20708.1 - 1.1e-05 25.7 4.7 0.00054 20.3 3.2 2.3 2 0 0 2 2 2 2 Mitochondrial ribosomal protein mL59 NADHdh-2_N PF12155.8 EWM20709.1 - 0.067 13.6 3.6 4 7.9 0.1 3.2 2 2 0 2 2 2 0 NADH dehydrogenase subunit 2 N-terminal Rhodanese PF00581.20 EWM20710.1 - 1.8e-08 34.8 0.3 1.4e-07 32.0 0.3 2.0 1 1 0 1 1 1 1 Rhodanese-like domain Methyltransf_16 PF10294.9 EWM20711.1 - 0.001 18.8 0.0 0.0013 18.5 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Abhydrolase_1 PF00561.20 EWM20712.1 - 0.019 14.6 0.1 0.57 9.8 0.0 2.4 2 1 0 2 2 2 0 alpha/beta hydrolase fold MHC_I PF00129.18 EWM20712.1 - 0.26 10.8 0.0 0.38 10.3 0.0 1.2 1 0 0 1 1 1 0 Class I Histocompatibility antigen, domains alpha 1 and 2 Abhydrolase_6 PF12697.7 EWM20712.1 - 0.31 11.6 3.8 0.1 13.2 0.5 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase family BNIP3 PF06553.12 EWM20715.1 - 0.12 12.1 0.0 0.13 11.9 0.0 1.0 1 0 0 1 1 1 0 BNIP3 PP-binding PF00550.25 EWM20716.1 - 9.9e-10 38.6 0.3 1.6e-09 38.0 0.3 1.4 1 1 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 EWM20716.1 - 0.073 13.3 0.5 0.089 13.0 0.5 1.3 1 0 0 1 1 1 0 Acyl-carrier Pheromone PF08015.11 EWM20718.1 - 1.8 9.7 6.7 13 7.0 0.7 2.9 3 0 0 3 3 3 0 Fungal mating-type pheromone cNMP_binding PF00027.29 EWM20719.1 - 3.9e-08 33.2 0.0 4.9e-07 29.7 0.0 2.4 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 EWM20719.1 - 0.0018 17.9 0.0 0.0048 16.6 0.0 1.7 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 EWM20719.1 - 0.016 14.9 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) AOX PF01786.17 EWM20720.1 - 5.2e-06 26.2 0.0 5.2e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Alternative oxidase HAP1_N PF04849.13 EWM20720.1 - 0.1 11.8 0.9 0.13 11.4 0.9 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Amidase PF01425.21 EWM20721.1 - 6.5e-08 32.0 0.0 7.3e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Amidase Mito_fiss_reg PF05308.11 EWM20722.1 - 3.9 7.5 6.0 4.9 7.2 6.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator AOX PF01786.17 EWM20723.1 - 6.2e-15 55.4 0.1 9.1e-15 54.8 0.1 1.1 1 0 0 1 1 1 1 Alternative oxidase DUF501 PF04417.12 EWM20723.1 - 0.13 12.1 0.1 1.3 8.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF501) Pkinase PF00069.25 EWM20724.1 - 6.4e-35 120.8 0.0 9.1e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM20724.1 - 3e-16 59.5 0.0 1.8e-14 53.7 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EWM20724.1 - 0.0022 17.4 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EWM20724.1 - 0.066 13.1 0.9 0.13 12.2 0.5 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family VEGF_C PF14554.6 EWM20724.1 - 0.12 12.5 0.3 0.22 11.6 0.3 1.4 1 0 0 1 1 1 0 VEGF heparin-binding domain Kdo PF06293.14 EWM20724.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EWM20725.1 - 8.5e-31 107.3 0.0 1.1e-30 106.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM20725.1 - 9.5e-15 54.6 0.0 1.3e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EWM20725.1 - 0.0011 18.3 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EWM20725.1 - 0.033 14.1 1.0 0.071 13.0 0.4 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EWM20725.1 - 0.071 12.5 0.0 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family VEGF_C PF14554.6 EWM20725.1 - 0.079 13.1 0.3 0.15 12.2 0.3 1.4 1 0 0 1 1 1 0 VEGF heparin-binding domain Pkinase_fungal PF17667.1 EWM20725.1 - 0.23 10.2 0.0 0.3 9.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Ski2_N PF17911.1 EWM20726.1 - 0.36 10.6 2.0 0.59 9.9 2.0 1.4 1 1 0 1 1 1 0 Ski2 N-terminal region SRP-alpha_N PF04086.13 EWM20728.1 - 6.5 6.6 5.6 8.1 6.3 5.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Helicase_C PF00271.31 EWM20730.1 - 1.2e-12 48.1 0.0 3.1e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EWM20730.1 - 9.7e-07 28.7 0.0 1.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase HA2 PF04408.23 EWM20730.1 - 7.3e-05 23.0 0.6 0.00048 20.4 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) AAA_22 PF13401.6 EWM20730.1 - 0.00058 20.2 0.0 0.0038 17.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EWM20730.1 - 0.0035 17.7 0.0 0.0064 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EWM20730.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain TCP PF03634.13 EWM20731.1 - 6.2 7.4 10.3 11 6.6 10.3 1.3 1 1 0 1 1 1 0 TCP family transcription factor DUF21 PF01595.20 EWM20734.1 - 3.9e-28 98.4 2.2 4.3e-28 98.2 0.1 2.1 3 0 0 3 3 3 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 EWM20734.1 - 0.065 13.7 0.0 2.9 8.4 0.0 3.0 2 1 0 2 2 2 0 CBS domain PLDc_N PF13396.6 EWM20734.1 - 0.2 11.6 0.8 0.44 10.5 0.8 1.6 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal DUF21 PF01595.20 EWM20735.1 - 3.2e-10 40.0 1.1 5.2e-10 39.3 1.1 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain WD40 PF00400.32 EWM20739.1 - 1.1e-06 29.2 0.3 0.059 14.3 0.1 2.7 3 0 0 3 3 3 2 WD domain, G-beta repeat HlyIII PF03006.20 EWM20740.1 - 3.1e-11 43.4 7.3 5.8e-11 42.5 7.3 1.4 1 0 0 1 1 1 1 Haemolysin-III related HNH PF01844.23 EWM20742.1 - 0.00095 19.3 4.6 0.0012 19.0 1.2 2.4 2 1 0 2 2 2 1 HNH endonuclease Zn_clus PF00172.18 EWM20744.1 - 1.7e-05 24.9 7.9 4.6e-05 23.4 7.9 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAP_fibrillin PF04755.12 EWM20745.1 - 3.5e-19 69.5 0.4 2.9e-15 56.7 0.0 2.1 1 1 1 2 2 2 2 PAP_fibrillin AI-2E_transport PF01594.16 EWM20746.1 - 6.1e-29 101.2 9.4 7e-29 101.0 9.4 1.0 1 0 0 1 1 1 1 AI-2E family transporter HAD_2 PF13419.6 EWM20750.1 - 4.8e-10 39.8 0.0 7.7e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EWM20750.1 - 0.00045 20.2 0.1 0.00087 19.3 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EWM20750.1 - 0.0033 17.7 0.0 0.0048 17.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Activator_LAG-3 PF11498.8 EWM20756.1 - 0.02 13.9 22.6 0.021 13.8 22.6 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Pex14_N PF04695.13 EWM20756.1 - 0.22 12.2 11.9 0.23 12.1 11.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 EWM20756.1 - 0.34 10.9 10.1 0.34 10.8 10.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 EWM20756.1 - 0.4 9.3 17.2 0.44 9.2 17.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal GET2 PF08690.10 EWM20756.1 - 1.7 8.3 5.5 1.9 8.1 5.5 1.0 1 0 0 1 1 1 0 GET complex subunit GET2 Spt20 PF12090.8 EWM20756.1 - 3 7.4 15.7 3.2 7.3 15.7 1.0 1 0 0 1 1 1 0 Spt20 family GST_N_3 PF13417.6 EWM20757.1 - 1.3e-08 35.1 0.1 7.9e-07 29.4 0.1 2.9 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EWM20757.1 - 8.1e-05 22.8 0.2 0.0015 18.8 0.0 2.7 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain AMP-binding PF00501.28 EWM20762.1 - 9e-89 298.0 0.0 1.3e-88 297.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EWM20762.1 - 2.5e-24 86.0 0.0 6e-24 84.8 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EWM20762.1 - 1.4e-19 69.8 1.0 3.1e-19 68.6 1.0 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding PF00501.28 EWM20763.1 - 3.9e-63 213.5 0.0 5.3e-63 213.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EWM20763.1 - 8.8e-20 70.4 1.0 2e-19 69.2 1.0 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus DUF3701 PF12482.8 EWM20763.1 - 0.054 13.6 0.0 0.25 11.4 0.0 2.1 2 0 0 2 2 2 0 Phage integrase protein Cellulase PF00150.18 EWM20764.1 - 1.1e-07 31.5 0.0 1.4e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PC-Esterase PF13839.6 EWM20765.1 - 0.00022 21.1 0.0 0.00031 20.6 0.0 1.2 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p HSP70 PF00012.20 EWM20768.1 - 8.8e-37 126.6 6.6 3e-29 101.7 0.1 3.0 3 0 0 3 3 3 2 Hsp70 protein CCDC-167 PF15188.6 EWM20768.1 - 0.77 10.1 8.7 3 8.3 5.1 2.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 BSP_II PF05432.11 EWM20768.1 - 3.7 7.2 12.2 0.81 9.3 8.0 1.9 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) HSP70 PF00012.20 EWM20769.1 - 4.7e-37 127.4 5.9 2.8e-29 101.8 0.1 3.0 3 0 0 3 3 3 2 Hsp70 protein CCDC-167 PF15188.6 EWM20769.1 - 0.84 10.0 5.1 2.8 8.4 5.1 1.9 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 BSP_II PF05432.11 EWM20769.1 - 4 7.1 12.2 0.75 9.4 8.0 1.7 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Glyco_hydro_44 PF12891.7 EWM20771.1 - 0.089 12.7 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Glycoside hydrolase family 44 Galactosyl_T PF01762.21 EWM20772.1 - 1.3e-09 38.2 0.0 2.6e-09 37.2 0.0 1.5 1 1 0 1 1 1 1 Galactosyltransferase Methyltransf_21 PF05050.12 EWM20773.1 - 1.3e-09 38.3 0.0 1.9e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain B3 PF02362.21 EWM20773.1 - 0.0044 16.8 0.0 0.0092 15.8 0.0 1.5 1 0 0 1 1 1 1 B3 DNA binding domain HSP70 PF00012.20 EWM20774.1 - 4.3e-36 124.3 0.0 5.4e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EWM20774.1 - 0.0048 15.8 0.7 0.0091 14.8 0.0 1.7 3 0 0 3 3 3 1 MreB/Mbl protein SfsA_N PF17746.1 EWM20775.1 - 0.011 15.8 0.2 0.024 14.8 0.2 1.6 1 1 0 1 1 1 0 SfsA N-terminal OB domain RVT_2 PF07727.14 EWM20777.1 - 1.7e-43 149.0 0.0 3.3e-43 148.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ATP_synt_H PF05493.13 EWM20777.1 - 0.091 13.2 0.9 0.24 11.9 0.9 1.7 1 0 0 1 1 1 0 ATP synthase subunit H RVT_2 PF07727.14 EWM20779.1 - 2e-67 227.4 0.0 3.2e-67 226.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3213 PF11491.8 EWM20779.1 - 0.017 15.3 0.0 6.3 7.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3213) DEDD_Tnp_IS110 PF01548.17 EWM20779.1 - 0.055 13.3 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Transposase CDC45 PF02724.14 EWM20779.1 - 0.065 11.5 8.9 0.1 10.9 0.0 2.1 2 0 0 2 2 2 0 CDC45-like protein RCC1 PF00415.18 EWM20781.1 - 5.3e-67 222.3 23.4 2.4e-11 44.1 0.0 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EWM20781.1 - 1.4e-38 129.9 28.7 4.2e-08 32.8 1.7 7.3 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Kelch_2 PF07646.15 EWM20781.1 - 0.02 14.9 0.6 8.4 6.6 0.1 3.8 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.6 EWM20781.1 - 0.24 11.4 4.1 1.3 9.1 0.5 3.3 3 0 0 3 3 3 0 Galactose oxidase, central domain DUF4213 PF13938.6 EWM20781.1 - 0.26 11.6 4.6 1.1e+02 3.1 0.0 5.0 4 1 0 4 4 4 0 Putative heavy-metal chelation XRN_M PF17846.1 EWM20782.1 - 0.0099 14.9 0.2 0.014 14.3 0.2 1.1 1 0 0 1 1 1 1 Xrn1 helical domain GRP PF07172.11 EWM20782.1 - 0.016 15.8 5.9 0.029 15.0 5.9 1.3 1 0 0 1 1 1 0 Glycine rich protein family DIOX_N PF14226.6 EWM20785.1 - 2.8e-31 108.7 0.0 4.4e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EWM20785.1 - 6.6e-20 71.5 0.0 1.2e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ATP-sulfurylase PF01747.17 EWM20785.1 - 0.034 13.6 0.0 3.6 7.0 0.0 2.2 2 0 0 2 2 2 0 ATP-sulfurylase 2OG-FeII_Oxy PF03171.20 EWM20786.1 - 7e-20 71.4 0.0 1.4e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EWM20786.1 - 4.5e-14 53.2 0.1 7.5e-14 52.5 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal ATP-sulfurylase PF01747.17 EWM20786.1 - 0.049 13.1 0.0 4.8 6.6 0.0 2.2 2 0 0 2 2 2 0 ATP-sulfurylase XRN_N PF03159.18 EWM20789.1 - 0.0035 16.8 0.0 0.0045 16.4 0.0 1.1 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus V-ATPase_H_N PF03224.14 EWM20792.1 - 0.00074 18.9 0.0 0.00077 18.8 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_N PF03224.14 EWM20794.1 - 6.5e-06 25.7 0.0 7.4e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 V-ATPase subunit H H-kinase_dim PF02895.14 EWM20794.1 - 0.15 12.5 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain ThrE_2 PF12821.7 EWM20795.1 - 4.5e-10 39.7 12.3 4.5e-10 39.7 12.3 1.6 1 1 1 2 2 2 1 Threonine/Serine exporter, ThrE ThrE PF06738.12 EWM20795.1 - 9e-07 28.5 20.2 1e-05 25.1 12.8 2.0 2 0 0 2 2 2 2 Putative threonine/serine exporter Pribosyltran PF00156.27 EWM20796.1 - 1.8e-13 50.3 0.0 3.4e-13 49.4 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EWM20796.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase ThrE PF06738.12 EWM20797.1 - 3.3e-45 154.4 22.3 2e-40 138.7 4.3 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EWM20797.1 - 3.7e-12 46.5 25.9 5e-10 39.6 10.2 2.5 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE Mso1_Sec1_bdg PF14475.6 EWM20799.1 - 6.5 6.4 9.3 1e+02 2.6 0.0 4.8 2 2 4 6 6 6 0 Sec1-binding region of Mso1 Prefoldin PF02996.17 EWM20801.1 - 6.3e-26 90.7 0.5 9.7e-26 90.0 0.2 1.5 1 1 0 1 1 1 1 Prefoldin subunit BORCS7 PF16088.5 EWM20801.1 - 0.0036 17.5 2.1 0.034 14.4 0.1 2.3 2 0 0 2 2 2 1 BLOC-1-related complex sub-unit 7 Prefoldin_2 PF01920.20 EWM20801.1 - 0.01 15.8 5.2 0.14 12.1 0.9 2.3 2 1 0 2 2 2 0 Prefoldin subunit Serine_rich PF08824.10 EWM20801.1 - 0.016 15.2 0.3 0.17 11.9 0.0 2.1 2 0 0 2 2 2 0 Serine rich protein interaction domain APG17 PF04108.12 EWM20801.1 - 0.017 14.2 0.2 0.025 13.7 0.2 1.2 1 1 0 1 1 1 0 Autophagy protein Apg17 ING PF12998.7 EWM20801.1 - 0.021 15.4 0.7 0.11 13.1 0.4 2.2 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Spc7 PF08317.11 EWM20801.1 - 0.031 13.2 4.5 0.86 8.4 0.2 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Spectrin PF00435.21 EWM20801.1 - 0.036 14.5 0.3 6.4 7.3 0.0 2.2 2 0 0 2 2 2 0 Spectrin repeat DASH_Dad2 PF08654.10 EWM20801.1 - 0.075 13.5 6.1 0.1 13.1 1.3 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad2 SYCE1 PF15233.6 EWM20801.1 - 0.11 12.6 3.6 0.74 9.9 0.2 2.1 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 Methyltransf_32 PF13679.6 EWM20801.1 - 0.19 11.7 1.5 0.71 9.8 0.3 1.9 1 1 1 2 2 2 0 Methyltransferase domain TPR_MLP1_2 PF07926.12 EWM20801.1 - 0.32 11.0 9.6 0.36 10.9 0.4 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein SlyX PF04102.12 EWM20801.1 - 2.8 8.6 6.0 2.1 9.0 0.2 2.5 2 1 0 2 2 2 0 SlyX Rubredoxin PF00301.20 EWM20802.1 - 0.00053 20.0 7.4 0.0081 16.2 7.4 2.1 1 1 0 1 1 1 1 Rubredoxin ADK_lid PF05191.14 EWM20802.1 - 0.024 14.6 1.7 0.043 13.8 1.7 1.4 1 0 0 1 1 1 0 Adenylate kinase, active site lid TF_Zn_Ribbon PF08271.12 EWM20802.1 - 0.039 13.5 2.3 0.94 9.0 0.2 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding HypA PF01155.19 EWM20802.1 - 0.088 12.8 0.3 0.13 12.3 0.3 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RanBP PF00641.18 EWM20802.1 - 0.2 11.0 3.0 2 7.8 0.1 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-RRN7 PF11781.8 EWM20802.1 - 0.27 11.0 5.4 0.69 9.6 0.1 2.6 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 UPF0547 PF10571.9 EWM20802.1 - 0.33 11.1 6.8 2.8 8.1 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 PHD_2 PF13831.6 EWM20802.1 - 3.2 7.4 5.8 3.9 7.1 0.3 2.2 2 0 0 2 2 2 0 PHD-finger DUF4047 PF13256.6 EWM20803.1 - 0.08 13.1 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) XRN_M PF17846.1 EWM20807.1 - 4.1e-38 131.5 2.0 4.6e-26 91.8 0.1 2.0 1 1 1 2 2 2 2 Xrn1 helical domain XRN_N PF03159.18 EWM20808.1 - 3.1e-19 69.4 0.0 4.1e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Isochorismatase PF00857.20 EWM20811.1 - 1.5e-06 28.5 0.2 2.7e-06 27.7 0.2 1.3 1 0 0 1 1 1 1 Isochorismatase family LSM PF01423.22 EWM20813.1 - 3.4e-13 49.1 0.7 4.1e-13 48.8 0.7 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EWM20813.1 - 0.0017 18.4 0.0 0.002 18.2 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Peptidase_C12 PF01088.21 EWM20814.1 - 6.3e-21 75.1 0.0 6.6e-21 75.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Pet100 PF09803.9 EWM20818.1 - 4.7e-11 43.1 0.0 6.1e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Pet100 Thr_dehydrat_C PF00585.18 EWM20818.1 - 0.11 12.3 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 C-terminal regulatory domain of Threonine dehydratase FMN_dh PF01070.18 EWM20821.1 - 4.5e-79 266.0 0.0 5.8e-79 265.6 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase TMP-TENI PF02581.17 EWM20821.1 - 0.0043 16.4 0.6 2.1 7.7 0.1 2.2 2 0 0 2 2 2 2 Thiamine monophosphate synthase DUF4653 PF15546.6 EWM20821.1 - 0.035 13.7 0.1 0.053 13.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) DHDPS PF00701.22 EWM20824.1 - 4.6e-36 124.0 0.0 7.9e-36 123.2 0.0 1.3 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family tRNA-synt_His PF13393.6 EWM20824.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Histidyl-tRNA synthetase zf-rbx1 PF12678.7 EWM20825.1 - 3.8e-20 71.9 5.6 5.5e-20 71.4 5.6 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EWM20825.1 - 1.5e-14 53.8 6.1 2.4e-14 53.2 6.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EWM20825.1 - 1.2e-08 35.1 10.1 1e-07 32.2 10.1 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EWM20825.1 - 4.6e-08 32.8 6.3 6.2e-07 29.1 3.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EWM20825.1 - 1.3e-06 28.2 3.8 2.6e-06 27.2 3.8 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EWM20825.1 - 3.9e-06 26.7 3.8 7e-06 25.9 3.8 1.4 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EWM20825.1 - 5.6e-06 26.3 1.5 8.5e-06 25.7 0.7 1.8 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EWM20825.1 - 0.00011 22.0 7.0 0.00022 21.0 2.2 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 EWM20825.1 - 0.00029 20.5 5.5 0.001 18.8 1.3 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 EWM20825.1 - 0.0016 18.2 6.5 0.0031 17.3 1.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EWM20825.1 - 0.0036 16.9 3.6 0.0036 16.9 3.6 2.2 2 1 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 EWM20825.1 - 0.021 14.6 1.0 0.042 13.7 1.0 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3H2C3 PF17122.5 EWM20825.1 - 0.047 13.7 6.2 0.094 12.8 3.2 2.4 2 1 0 2 2 2 0 Zinc-finger TerY_C PF15616.6 EWM20825.1 - 0.24 11.5 2.4 0.14 12.3 0.5 1.5 1 1 0 1 1 1 0 TerY-C metal binding domain zf-C3HC4_4 PF15227.6 EWM20825.1 - 0.46 10.7 7.8 1.8 8.8 4.1 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Baculo_RING PF05883.11 EWM20825.1 - 0.65 10.0 3.8 5.5 7.0 3.8 2.1 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain ABC_ATPase PF09818.9 EWM20827.1 - 2.3e-110 369.5 0.0 3.4e-110 368.9 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.6 EWM20827.1 - 0.014 15.9 0.0 0.021 15.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EWM20827.1 - 0.12 12.2 0.2 0.24 11.2 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_ATPase PF09818.9 EWM20828.1 - 5.2e-38 131.0 0.0 7.7e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 Predicted ATPase of the ABC class Zn_clus PF00172.18 EWM20829.1 - 2.1e-07 31.0 11.8 3.4e-07 30.3 11.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 EWM20830.1 - 2.1e-07 31.0 11.8 3.4e-07 30.3 11.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 EWM20831.1 - 1.9e-07 31.1 11.8 3e-07 30.4 11.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 EWM20832.1 - 2.7e-78 263.0 0.0 3.8e-78 262.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM20832.1 - 3.8e-33 114.9 0.0 5.3e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EWM20832.1 - 2.8e-07 30.1 0.2 4.3e-07 29.5 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EWM20832.1 - 0.00012 21.0 0.0 0.00024 20.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EWM20832.1 - 0.00037 19.9 0.0 0.0007 19.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EWM20832.1 - 0.001 19.1 0.1 0.71 9.7 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 EWM20832.1 - 0.0042 16.1 0.0 0.0064 15.5 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.20 EWM20832.1 - 0.056 13.0 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF3432 PF11914.8 EWM20833.1 - 0.4 10.9 5.9 0.95 9.8 5.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3432) Gly-zipper_Omp PF13488.6 EWM20835.1 - 5.5e-08 32.7 48.9 0.0007 19.5 30.6 2.5 1 1 1 2 2 2 2 Glycine zipper Gly-zipper_OmpA PF13436.6 EWM20835.1 - 4.2e-07 29.6 44.6 0.00026 20.7 21.8 2.6 1 1 1 2 2 2 2 Glycine-zipper domain Gly-zipper_YMGG PF13441.6 EWM20835.1 - 1.1e-06 28.3 41.8 0.0029 17.3 26.6 2.6 1 1 1 2 2 2 2 YMGG-like Gly-zipper DUF456 PF04306.13 EWM20835.1 - 0.03 14.6 32.0 6.4e+02 0.6 32.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF456) Romo1 PF10247.9 EWM20835.1 - 0.19 12.1 47.0 9 6.7 6.9 4.6 1 1 1 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Rick_17kDa_Anti PF05433.15 EWM20835.1 - 0.47 10.3 51.5 1.8e+04 -14.7 51.5 3.9 1 1 0 1 1 1 0 Glycine zipper 2TM domain MccV PF17508.2 EWM20835.1 - 0.82 10.3 26.7 2.8 8.6 12.1 2.6 1 1 1 2 2 2 0 Microcin V bacteriocin Bacteriocin_IIc PF10439.9 EWM20835.1 - 0.82 9.8 47.0 1.8e+04 -14.7 47.0 2.9 1 1 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF1269 PF06897.12 EWM20835.1 - 1.4 9.3 31.7 1.8e+04 -10.2 31.7 3.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1269) SBBP PF06739.11 EWM20836.1 - 8.9e-08 32.0 30.3 0.00059 19.8 1.0 4.2 5 0 0 5 5 5 3 Beta-propeller repeat DUF5122 PF17164.4 EWM20836.1 - 9.4e-08 32.2 0.6 0.25 11.6 0.0 4.3 4 0 0 4 4 4 3 Domain of unknown function (DUF5122) beta-propeller DUF4346 PF14251.6 EWM20836.1 - 0.0094 16.0 0.0 4.5 7.3 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4346) GCV_H PF01597.19 EWM20836.1 - 0.027 14.3 0.2 4 7.4 0.0 3.2 3 1 1 4 4 4 0 Glycine cleavage H-protein Aft1_OSA PF11785.8 EWM20836.1 - 0.039 14.4 3.5 20 5.7 0.0 4.6 6 0 0 6 6 6 0 Aft1 osmotic stress response (OSM) domain SspH PF08141.12 EWM20836.1 - 0.19 11.9 0.0 57 3.9 0.0 3.1 3 0 0 3 3 3 0 Small acid-soluble spore protein H family IL4Ra_N PF09238.10 EWM20836.1 - 0.27 11.6 0.0 1.2e+02 3.1 0.0 3.0 3 0 0 3 3 3 0 Interleukin-4 receptor alpha chain, N-terminal Glyco_hydro_49 PF03718.13 EWM20836.1 - 1.5 8.9 4.6 33 4.5 0.1 3.4 4 0 0 4 4 4 0 Glycosyl hydrolase family 49 DUF5122 PF17164.4 EWM20839.1 - 0.018 15.3 0.3 0.75 10.1 0.0 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF5122) beta-propeller Alpha_adaptinC2 PF02883.20 EWM20839.1 - 0.16 12.3 0.0 0.29 11.5 0.0 1.3 1 0 0 1 1 1 0 Adaptin C-terminal domain SBBP PF06739.11 EWM20839.1 - 0.21 11.6 13.1 0.22 11.6 1.1 3.2 3 0 0 3 3 3 0 Beta-propeller repeat PT PF04886.12 EWM20839.1 - 0.96 9.1 35.5 0.023 14.2 18.7 3.1 3 0 0 3 3 3 0 PT repeat RVT_2 PF07727.14 EWM20840.1 - 1.6e-67 227.7 0.0 2.8e-67 226.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 EWM20840.1 - 8.3e-19 67.9 0.0 2e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 EWM20840.1 - 2e-09 37.2 0.0 6.3e-09 35.6 0.0 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain DEDD_Tnp_IS110 PF01548.17 EWM20840.1 - 0.031 14.1 0.1 0.065 13.1 0.1 1.5 1 0 0 1 1 1 0 Transposase Hist_deacetyl PF00850.19 EWM20846.1 - 0.00034 20.2 0.0 0.00093 18.8 0.0 1.7 1 1 0 1 1 1 1 Histone deacetylase domain DUF4645 PF15488.6 EWM20846.1 - 1.4 8.3 4.8 1.9 7.8 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4645) MFS_1 PF07690.16 EWM20847.1 - 7.9e-09 34.9 10.1 6.5e-06 25.3 8.5 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EWM20847.1 - 1.4e-07 30.8 1.0 2e-07 30.2 0.4 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter FTR1 PF03239.14 EWM20847.1 - 0.077 12.2 0.0 0.23 10.6 0.0 1.4 1 1 0 1 1 1 0 Iron permease FTR1 family IQ PF00612.27 EWM20849.1 - 0.0098 15.6 0.6 0.019 14.7 0.6 1.5 1 0 0 1 1 1 1 IQ calmodulin-binding motif P63C PF10546.9 EWM20849.1 - 0.023 15.3 0.0 0.031 14.8 0.0 1.2 1 0 0 1 1 1 0 P63C domain DAHP_synth_1 PF00793.20 EWM20849.1 - 0.1 11.4 0.0 0.13 11.1 0.0 1.0 1 0 0 1 1 1 0 DAHP synthetase I family Cyclin PF08613.11 EWM20851.1 - 1.8e-19 70.7 0.0 3e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EWM20851.1 - 2.2e-06 27.5 0.0 3.1e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain PTH2 PF01981.16 EWM20852.1 - 1.4e-40 138.2 0.1 2.1e-40 137.7 0.1 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 PTH2 PF01981.16 EWM20853.1 - 2e-13 50.6 0.1 3.3e-13 49.9 0.1 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 AhpC-TSA PF00578.21 EWM20854.1 - 5.3e-25 87.7 0.0 1.5e-24 86.2 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 EWM20854.1 - 8e-10 38.4 0.0 1.5e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 EWM20854.1 - 2.5e-07 30.5 0.0 6.3e-07 29.2 0.0 1.7 1 1 0 1 1 1 1 Redoxin Glyco_transf_92 PF01697.27 EWM20857.1 - 1.6e-13 50.9 0.0 2.4e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 EWM20857.1 - 0.13 12.8 0.1 0.61 10.6 0.1 2.1 1 1 0 1 1 1 0 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 EWM20858.1 - 2.3e-13 50.4 0.0 3.7e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 EWM20858.1 - 0.18 12.4 0.2 0.93 10.1 0.0 2.3 2 1 0 2 2 2 0 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 EWM20859.1 - 2.3e-13 50.4 0.0 3.3e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 EWM20859.1 - 0.092 13.3 0.1 0.45 11.1 0.1 2.1 1 1 0 1 1 1 0 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 EWM20860.1 - 6e-14 52.3 0.0 9.4e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_transf_92 PF01697.27 EWM20863.1 - 4.6e-13 49.4 0.0 7.4e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_transf_92 PF01697.27 EWM20864.1 - 1.6e-14 54.2 0.0 2.6e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 EWM20864.1 - 0.043 14.3 0.0 0.19 12.3 0.0 2.0 1 1 0 1 1 1 0 Glycosyl transferase family 2 Suf PF05843.14 EWM20866.1 - 1.8e-05 24.9 0.0 2.4 8.0 0.0 3.9 4 0 0 4 4 4 3 Suppressor of forked protein (Suf) HAT PF02184.16 EWM20866.1 - 0.00012 21.9 0.3 0.037 14.0 0.2 3.3 3 0 0 3 3 3 1 HAT (Half-A-TPR) repeat TPR_16 PF13432.6 EWM20866.1 - 0.019 15.6 4.5 2.4 8.9 1.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat U3_assoc_6 PF08640.11 EWM20866.1 - 0.088 12.9 0.3 7.7 6.7 0.0 2.9 3 0 0 3 3 3 0 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 EWM20866.1 - 0.1 13.5 0.2 0.1 13.5 0.2 4.5 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 EWM20867.1 - 1.2e-30 104.0 8.1 2.1e-06 27.3 0.2 5.6 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 EWM20867.1 - 4.9e-28 95.0 12.9 5.3e-07 29.3 0.9 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 EWM20867.1 - 7e-26 89.6 17.7 1.6e-07 30.9 0.0 6.1 4 3 2 6 6 6 5 TPR repeat TPR_8 PF13181.6 EWM20867.1 - 1.3e-23 81.2 4.1 0.00012 22.1 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 EWM20867.1 - 9.2e-23 78.9 9.9 0.00042 20.5 0.0 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 EWM20867.1 - 2.4e-22 79.3 22.7 4.7e-09 36.7 1.8 4.6 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 EWM20867.1 - 7.6e-17 61.4 9.4 7.9e-06 26.1 0.0 4.3 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 EWM20867.1 - 2.8e-14 52.6 12.5 2e-05 25.0 0.2 5.8 3 3 3 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 EWM20867.1 - 9e-10 37.9 7.3 0.023 14.7 0.2 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 EWM20867.1 - 2.7e-09 37.1 9.6 0.0006 20.3 0.5 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 EWM20867.1 - 1.2e-08 35.0 9.2 8.2e-05 22.7 0.8 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EWM20867.1 - 2.5e-08 33.5 15.7 0.08 12.8 1.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 EWM20867.1 - 5.4e-05 23.6 10.8 0.58 10.7 0.3 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_15 PF13429.6 EWM20867.1 - 0.0026 17.0 0.3 0.82 8.8 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 EWM20867.1 - 0.0061 16.3 5.0 0.026 14.2 0.2 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat-like domain ANAPC3 PF12895.7 EWM20867.1 - 0.014 15.6 2.6 0.48 10.7 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 EWM20867.1 - 0.034 13.5 2.2 7.1 5.9 0.2 3.2 3 0 0 3 3 3 0 MalT-like TPR region RPN7 PF10602.9 EWM20867.1 - 0.23 11.2 1.5 2.6 7.7 0.1 2.7 3 0 0 3 3 3 0 26S proteasome subunit RPN7 TPR_4 PF07721.14 EWM20867.1 - 0.27 12.0 14.9 2.5 9.0 0.1 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 EWM20867.1 - 0.28 11.1 7.3 3.3 7.6 0.3 3.7 3 2 1 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal HAT PF02184.16 EWM20868.1 - 7.3e-11 41.8 8.7 6.8e-08 32.3 0.1 3.3 3 0 0 3 3 3 2 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 EWM20868.1 - 4.1e-05 24.1 1.2 0.012 16.4 0.1 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat U3_assoc_6 PF08640.11 EWM20868.1 - 0.019 15.0 4.2 0.054 13.6 1.1 2.2 1 1 1 2 2 2 0 U3 small nucleolar RNA-associated protein 6 TPR_2 PF07719.17 EWM20868.1 - 0.02 15.0 0.0 2.2 8.6 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF615 PF04751.14 EWM20868.1 - 0.057 13.4 1.5 0.097 12.7 1.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF615) MttA_Hcf106 PF02416.16 EWM20869.1 - 0.00074 18.8 0.0 0.0013 18.0 0.0 1.4 1 0 0 1 1 1 1 mttA/Hcf106 family zinc-ribbons_6 PF07191.12 EWM20870.1 - 0.084 12.9 2.4 2.4 8.2 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbons YdjO PF14169.6 EWM20870.1 - 2.6 7.8 7.2 3.9 7.3 0.5 2.6 3 0 0 3 3 3 0 Cold-inducible protein YdjO Lung_7-TM_R PF06814.13 EWM20871.1 - 1.4e-24 86.9 0.2 1.8e-24 86.5 0.2 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 EWM20871.1 - 0.00045 19.7 3.7 0.00074 19.0 3.7 1.3 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain PX PF00787.24 EWM20873.1 - 4.1e-06 26.7 0.2 7.7e-05 22.7 0.2 2.3 1 1 0 1 1 1 1 PX domain Adenylate_cycl PF01295.18 EWM20874.1 - 0.099 11.3 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase, class-I Pkinase PF00069.25 EWM20875.1 - 3.2e-07 30.0 0.0 4.2e-07 29.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM20875.1 - 0.0037 16.6 0.0 0.0044 16.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pur_ac_phosph_N PF16656.5 EWM20876.1 - 7.6e-17 61.7 2.3 8e-17 61.6 0.1 2.3 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 EWM20876.1 - 3.3e-16 60.4 0.6 9.6e-16 58.9 0.0 2.0 3 0 0 3 3 3 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 EWM20876.1 - 3.6e-07 31.0 0.6 1.2e-06 29.3 0.6 1.9 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C AMP-binding PF00501.28 EWM20877.1 - 3.1e-10 39.2 0.0 3.7e-10 39.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme CAP_N PF01213.19 EWM20877.1 - 0.8 9.1 8.5 7.5 5.9 8.2 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal MOZ_SAS PF01853.18 EWM20878.1 - 3.2e-76 255.0 0.0 4.6e-76 254.5 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EWM20878.1 - 9.4e-16 57.2 0.2 2.4e-15 55.9 0.2 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 EWM20878.1 - 7.8e-15 54.5 0.3 1.7e-14 53.4 0.3 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 EWM20878.1 - 0.0012 19.3 0.0 0.0024 18.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EWM20878.1 - 0.019 15.2 0.0 0.045 14.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Amidase_6 PF12671.7 EWM20878.1 - 0.064 13.3 0.2 0.12 12.4 0.2 1.4 1 0 0 1 1 1 0 Putative amidase domain AMP-binding PF00501.28 EWM20879.1 - 2.2e-30 105.6 0.0 2.1e-28 99.1 0.0 2.6 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EWM20879.1 - 1.3e-18 67.8 1.0 2.2e-18 67.0 1.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PQ-loop PF04193.14 EWM20880.1 - 8.8e-07 28.6 0.2 8.8e-07 28.6 0.2 1.9 1 1 0 2 2 2 1 PQ loop repeat DUF5527 PF17665.1 EWM20880.1 - 0.012 15.1 0.5 0.021 14.3 0.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5527) CPP1-like PF11833.8 EWM20880.1 - 0.19 11.4 1.3 0.26 10.9 1.3 1.3 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF4149 PF13664.6 EWM20880.1 - 0.28 11.5 4.6 0.4 11.0 2.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) ABC2_membrane_3 PF12698.7 EWM20880.1 - 1.8 7.6 7.1 2.3 7.3 7.1 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Brix PF04427.18 EWM20883.1 - 8.6e-41 140.2 0.0 1.2e-40 139.7 0.0 1.2 1 0 0 1 1 1 1 Brix domain Ost4 PF10215.9 EWM20884.1 - 0.098 12.5 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Oligosaccaryltransferase 2-Hacid_dh_C PF02826.19 EWM20885.1 - 1.3e-60 203.9 0.0 1.9e-60 203.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EWM20885.1 - 4.7e-05 23.1 0.0 8e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 EWM20885.1 - 0.00029 21.0 0.2 0.00076 19.6 0.0 1.6 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 EWM20885.1 - 0.028 14.6 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EWM20885.1 - 0.036 13.7 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 EWM20886.1 - 2.3e-40 137.8 0.0 3.4e-40 137.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain OTU PF02338.19 EWM20887.1 - 2.1e-05 25.0 0.0 3e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EWM20887.1 - 0.013 14.9 0.0 0.038 13.5 0.0 1.7 2 0 0 2 2 2 0 Peptidase C65 Otubain Pho88 PF10032.9 EWM20889.1 - 1.2e-27 96.3 0.1 1.9e-27 95.7 0.1 1.2 1 0 0 1 1 1 1 Phosphate transport (Pho88) eIF3_N PF09440.10 EWM20889.1 - 6.5e-05 23.4 2.3 0.0013 19.2 0.6 2.2 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain Ank_2 PF12796.7 EWM20889.1 - 0.0003 21.3 0.1 0.0014 19.2 0.0 2.1 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 EWM20889.1 - 0.02 15.3 0.0 0.082 13.4 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeat Ank_4 PF13637.6 EWM20889.1 - 0.029 15.0 0.0 0.072 13.7 0.0 1.8 1 1 0 1 1 1 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 EWM20889.1 - 0.068 13.5 0.1 1.9 8.9 0.1 2.6 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 EWM20889.1 - 0.1 13.2 0.0 0.59 10.9 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat Ribosomal_60s PF00428.19 EWM20889.1 - 0.44 11.2 5.3 0.77 10.4 0.1 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein Pro_isomerase PF00160.21 EWM20892.1 - 1.2e-44 152.4 0.0 1.4e-44 152.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 PF00515.28 EWM20893.1 - 3.5e-13 48.8 7.1 2.5e-06 27.0 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EWM20893.1 - 4.6e-13 48.2 7.4 3e-06 26.9 0.3 3.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 EWM20893.1 - 5.5e-06 26.0 2.0 0.075 12.7 0.1 2.7 2 1 1 3 3 3 2 TPR repeat TPR_14 PF13428.6 EWM20893.1 - 0.00014 22.4 2.6 0.0059 17.3 0.7 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 EWM20893.1 - 0.0018 17.5 0.1 0.0033 16.7 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 EWM20893.1 - 0.0028 17.7 1.2 0.047 13.9 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EWM20893.1 - 0.0056 16.6 3.6 6.9 6.9 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat OSCP PF00213.18 EWM20893.1 - 0.025 14.7 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit TPR_9 PF13371.6 EWM20893.1 - 0.059 13.5 5.4 0.2 11.8 0.3 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 EWM20893.1 - 0.08 13.6 2.8 0.59 10.8 0.7 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EWM20893.1 - 0.2 12.4 0.9 4.2 8.2 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat PC-Esterase PF13839.6 EWM20895.1 - 7.7e-11 42.3 0.2 6.1e-09 36.0 0.2 2.3 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Inositol_P PF00459.25 EWM20896.1 - 1.2e-19 70.8 0.0 1.7e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family AAA PF00004.29 EWM20899.1 - 1.3e-12 48.3 0.0 2.3e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EWM20899.1 - 3.3e-05 23.7 0.0 6.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EWM20899.1 - 3.3e-05 24.2 0.2 0.41 10.9 0.0 3.0 2 1 1 3 3 3 2 AAA domain AAA_5 PF07728.14 EWM20899.1 - 6.8e-05 22.9 0.0 0.00015 21.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EWM20899.1 - 9.6e-05 22.8 2.9 0.00075 19.9 0.0 3.2 2 2 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.6 EWM20899.1 - 0.00013 22.0 0.0 0.00023 21.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EWM20899.1 - 0.00028 21.4 0.0 0.00058 20.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EWM20899.1 - 0.0042 16.8 0.0 0.0073 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EWM20899.1 - 0.0062 16.3 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 EWM20899.1 - 0.011 15.6 0.0 0.029 14.3 0.0 1.7 1 0 0 1 1 1 0 NTPase AAA_33 PF13671.6 EWM20899.1 - 0.017 15.3 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EWM20899.1 - 0.023 14.0 0.0 0.045 13.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 EWM20899.1 - 0.028 14.3 0.0 0.067 13.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 EWM20899.1 - 0.034 14.4 0.0 0.12 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 EWM20899.1 - 0.044 13.0 0.0 0.068 12.4 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain DNA_pol3_delta PF06144.13 EWM20899.1 - 0.053 13.3 0.0 0.086 12.6 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit RNA_helicase PF00910.22 EWM20899.1 - 0.061 13.7 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 EWM20899.1 - 0.069 13.2 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 EWM20899.1 - 0.11 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain IstB_IS21 PF01695.17 EWM20899.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EWM20899.1 - 0.12 12.0 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EWM20899.1 - 0.12 12.7 0.1 0.38 11.1 0.1 1.7 1 1 1 2 2 2 0 AAA domain AAA_assoc_2 PF16193.5 EWM20899.1 - 0.16 12.3 0.0 0.52 10.7 0.0 1.9 2 0 0 2 2 1 0 AAA C-terminal domain Polyoma_lg_T_C PF06431.11 EWM20899.1 - 0.19 10.6 0.0 0.3 9.9 0.0 1.2 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus NB-ARC PF00931.22 EWM20899.1 - 0.2 10.8 0.0 0.35 10.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Aminotran_4 PF01063.19 EWM20900.1 - 6e-33 114.6 0.0 7.6e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV TRIC PF05197.13 EWM20901.1 - 9.2e-08 31.9 0.3 1.5e-07 31.2 0.3 1.3 1 0 0 1 1 1 1 TRIC channel UPF0126 PF03458.13 EWM20901.1 - 0.0033 17.3 0.4 0.0033 17.3 0.4 2.1 2 0 0 2 2 2 1 UPF0126 domain B_lectin PF01453.24 EWM20901.1 - 0.057 14.0 0.0 0.091 13.3 0.0 1.3 1 0 0 1 1 1 0 D-mannose binding lectin YqjK PF13997.6 EWM20902.1 - 0.04 14.2 0.0 0.061 13.6 0.0 1.3 1 0 0 1 1 1 0 YqjK-like protein Diphthami_syn_2 PF01902.17 EWM20903.1 - 1.3e-21 77.2 0.0 5.3e-21 75.1 0.0 1.8 1 1 0 1 1 1 1 Diphthamide synthase tRNA_Me_trans PF03054.16 EWM20903.1 - 0.00071 18.5 0.1 0.00095 18.1 0.1 1.1 1 0 0 1 1 1 1 tRNA methyl transferase Arginosuc_synth PF00764.19 EWM20903.1 - 0.0014 18.0 0.0 0.0019 17.6 0.0 1.1 1 0 0 1 1 1 1 Arginosuccinate synthase HA2 PF04408.23 EWM20904.1 - 5.3e-16 58.9 0.2 1.4e-15 57.5 0.2 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EWM20904.1 - 4.6e-13 49.5 0.0 9.5e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain R3H PF01424.22 EWM20904.1 - 1.7e-08 34.3 0.0 4.5e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 R3H domain DEAD PF00270.29 EWM20904.1 - 8.6e-08 32.1 0.1 1.7e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 EWM20904.1 - 3.7e-07 30.4 0.0 7.7e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 EWM20904.1 - 0.0047 17.2 1.5 0.025 14.8 0.5 2.7 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 EWM20904.1 - 0.017 14.2 0.4 0.064 12.3 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein Peptidase_M20 PF01546.28 EWM20905.1 - 3.2e-32 111.9 0.0 5.7e-32 111.1 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EWM20905.1 - 2e-07 30.9 0.0 4.8e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EWM20905.1 - 0.014 15.1 0.0 0.036 13.8 0.0 1.6 2 0 0 2 2 2 0 Peptidase family M28 Ribosomal_L7Ae PF01248.26 EWM20906.1 - 5.3e-20 70.9 1.8 5.9e-20 70.8 0.8 1.6 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Gelsolin PF00626.22 EWM20907.1 - 0.00021 21.1 0.1 0.29 11.1 0.0 2.5 2 0 0 2 2 2 2 Gelsolin repeat Patatin PF01734.22 EWM20908.1 - 2.2e-06 28.0 0.1 0.004 17.3 0.0 2.3 2 0 0 2 2 2 2 Patatin-like phospholipase Rhomboid PF01694.22 EWM20909.1 - 5.9e-18 65.3 17.1 3.9e-17 62.7 8.3 2.2 2 1 1 3 3 3 2 Rhomboid family DER1 PF04511.15 EWM20909.1 - 0.035 14.1 2.0 0.11 12.4 2.0 2.0 1 1 0 1 1 1 0 Der1-like family Na_H_Exchanger PF00999.21 EWM20910.1 - 2.7e-30 105.4 20.8 2.3e-24 85.9 14.1 2.4 2 1 0 2 2 2 2 Sodium/hydrogen exchanger family DUF5367 PF17329.2 EWM20910.1 - 0.0038 17.3 0.8 0.014 15.5 0.8 1.9 1 0 0 1 1 1 1 Family of unknown function (DUF5367) TIC20 PF16166.5 EWM20912.1 - 2.6e-17 63.2 1.0 3.6e-17 62.7 1.0 1.2 1 0 0 1 1 1 1 Chloroplast import apparatus Tic20-like DUF1499 PF07386.11 EWM20913.1 - 8.2e-17 61.8 0.1 1.4e-16 61.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1499) FA_desaturase PF00487.24 EWM20915.1 - 1.5e-35 123.2 18.1 1.5e-35 123.2 18.1 1.8 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 EWM20915.1 - 5.9e-17 61.6 0.1 1.4e-16 60.4 0.1 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RNB PF00773.19 EWM20916.1 - 3.9e-25 88.9 0.0 1.4e-22 80.5 0.0 2.2 2 0 0 2 2 2 2 RNB domain RNase_II_C_S1 PF18614.1 EWM20916.1 - 0.18 11.8 2.3 0.43 10.6 0.1 2.8 3 0 0 3 3 3 0 RNase II-type exonuclease C-terminal S1 domain AAA PF00004.29 EWM20917.1 - 3.9e-41 140.6 0.0 6.9e-41 139.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EWM20917.1 - 1.3e-11 44.1 0.1 2.6e-11 43.1 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EWM20917.1 - 2.8e-10 40.0 0.0 6.9e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 EWM20917.1 - 1.7e-08 35.0 0.1 2.1e-05 25.0 0.1 2.6 2 1 1 3 3 2 1 AAA ATPase domain AAA_22 PF13401.6 EWM20917.1 - 7.1e-06 26.3 0.5 0.0086 16.3 0.0 3.2 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.14 EWM20917.1 - 8.5e-06 25.8 0.1 6.9e-05 22.9 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EWM20917.1 - 3e-05 24.2 0.0 6.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EWM20917.1 - 0.0001 22.1 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EWM20917.1 - 0.00064 20.1 0.0 0.0014 19.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 EWM20917.1 - 0.00081 19.2 0.0 0.0018 18.0 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 EWM20917.1 - 0.0014 19.2 0.0 0.0054 17.3 0.0 2.0 2 1 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 EWM20917.1 - 0.0032 16.9 0.0 0.0059 16.0 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 EWM20917.1 - 0.0041 16.3 0.0 0.0068 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 EWM20917.1 - 0.0048 17.1 0.0 0.017 15.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EWM20917.1 - 0.0052 16.3 0.0 0.012 15.1 0.0 1.7 1 1 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 EWM20917.1 - 0.0059 15.8 0.1 0.014 14.7 0.1 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain Sigma54_activat PF00158.26 EWM20917.1 - 0.0059 16.3 0.0 0.04 13.6 0.0 2.3 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.6 EWM20917.1 - 0.011 16.0 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EWM20917.1 - 0.015 15.1 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 EWM20917.1 - 0.025 14.0 0.2 0.08 12.3 0.0 1.9 3 0 0 3 3 3 0 KaiC AAA_24 PF13479.6 EWM20917.1 - 0.027 14.2 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EWM20917.1 - 0.029 14.4 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 EWM20917.1 - 0.032 14.3 0.0 0.064 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EWM20917.1 - 0.037 13.9 0.0 0.077 12.9 0.0 1.7 1 1 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 EWM20917.1 - 0.038 13.6 0.0 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 EWM20917.1 - 0.041 13.0 0.0 0.071 12.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF4200 PF13863.6 EWM20917.1 - 0.043 14.2 1.4 0.091 13.2 1.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) IFT57 PF10498.9 EWM20917.1 - 0.053 12.5 0.6 0.08 11.9 0.6 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 AAA_11 PF13086.6 EWM20917.1 - 0.054 13.3 0.3 0.2 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EWM20917.1 - 0.057 13.1 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EWM20917.1 - 0.06 12.8 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein PIF1 PF05970.14 EWM20917.1 - 0.073 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase ABC_tran PF00005.27 EWM20917.1 - 0.085 13.4 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Torsin PF06309.11 EWM20917.1 - 0.14 12.2 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 Torsin DUF3450 PF11932.8 EWM20917.1 - 0.52 9.6 2.5 0.79 9.0 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) MFS_1 PF07690.16 EWM20918.1 - 1e-10 41.1 9.7 1e-10 41.1 9.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EWM20918.1 - 0.00082 18.3 4.2 0.0011 17.9 4.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter GTP_EFTU PF00009.27 EWM20919.1 - 1.9e-53 180.9 0.1 2.9e-53 180.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 EWM20919.1 - 1.6e-45 153.7 1.1 3.9e-45 152.4 1.1 1.7 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 EWM20919.1 - 6.8e-20 70.9 0.0 1.6e-19 69.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EWM20919.1 - 2.5e-10 40.6 0.6 4.9e-10 39.7 0.6 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EWM20919.1 - 1.4e-05 25.1 0.0 3.2e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RF3_C PF16658.5 EWM20919.1 - 0.0001 22.2 0.0 0.00022 21.1 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Ras PF00071.22 EWM20919.1 - 0.0029 17.2 0.0 0.007 16.0 0.0 1.6 1 0 0 1 1 1 1 Ras family EFG_II PF14492.6 EWM20919.1 - 0.0088 16.1 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.10 EWM20919.1 - 0.018 14.5 0.0 0.084 12.3 0.0 2.1 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 EWM20919.1 - 0.099 12.7 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain DUF2150 PF09920.9 EWM20920.1 - 0.071 13.1 3.7 1.3 9.0 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2150) Ribosom_S12_S23 PF00164.25 EWM20921.1 - 3.7e-50 168.3 0.5 4.6e-50 168.0 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Carboxyl_trans PF01039.22 EWM20922.1 - 2.5e-185 616.8 0.0 3e-185 616.6 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 EWM20922.1 - 0.0069 15.9 0.3 0.031 13.8 0.0 2.1 2 1 0 2 2 2 1 Malonate decarboxylase gamma subunit (MdcE) PH PF00169.29 EWM20923.1 - 3.2e-08 34.0 0.0 6.1e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EWM20923.1 - 4.5e-06 27.0 0.0 9.9e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain R3H PF01424.22 EWM20924.1 - 8.2e-14 51.3 0.1 1.5e-13 50.5 0.1 1.4 1 0 0 1 1 1 1 R3H domain Na_trans_assoc PF06512.13 EWM20924.1 - 0.0052 17.1 7.2 0.0079 16.5 7.2 1.2 1 0 0 1 1 1 1 Sodium ion transport-associated PPP4R2 PF09184.11 EWM20924.1 - 0.046 13.3 5.5 0.08 12.5 5.5 1.3 1 0 0 1 1 1 0 PPP4R2 RPN2_C PF18004.1 EWM20924.1 - 0.11 12.4 3.1 0.2 11.6 3.1 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain RPA43_OB PF17875.1 EWM20924.1 - 2.8 8.6 6.8 4.8 7.8 6.8 1.4 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I CDC45 PF02724.14 EWM20924.1 - 7.6 4.7 15.8 11 4.1 15.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Cellulase PF00150.18 EWM20925.1 - 6e-37 127.6 0.0 8.3e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Furin-like_2 PF15913.5 EWM20927.1 - 0.12 12.6 5.8 0.18 12.0 0.4 2.6 2 0 0 2 2 2 0 Furin-like repeat, cysteine-rich TLC PF03219.14 EWM20928.1 - 3.5e-134 448.2 9.7 4.5e-134 447.9 9.7 1.0 1 0 0 1 1 1 1 TLC ATP/ADP transporter Cpn60_TCP1 PF00118.24 EWM20929.1 - 2.5e-165 550.8 0.2 2.9e-165 550.6 0.2 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ysc84 PF04366.12 EWM20929.1 - 0.00068 19.4 0.3 0.0019 18.0 0.0 1.9 2 0 0 2 2 2 1 Las17-binding protein actin regulator MFS_1 PF07690.16 EWM20930.1 - 0.008 15.1 0.8 0.011 14.7 0.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EWM20930.1 - 0.031 13.1 0.0 0.04 12.8 0.0 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter MFS_1_like PF12832.7 EWM20930.1 - 0.068 12.0 0.1 0.1 11.5 0.1 1.3 1 1 0 1 1 1 0 MFS_1 like family ADH_zinc_N PF00107.26 EWM20931.1 - 1.1e-10 41.6 0.0 2.3e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EWM20931.1 - 0.00027 20.8 0.0 0.00099 19.0 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EWM20931.1 - 0.0012 19.9 0.0 0.022 15.8 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EWM20932.1 - 9.6e-11 41.8 0.0 1.6e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EWM20932.1 - 0.0067 17.5 0.0 0.017 16.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EWM20933.1 - 2.2e-12 48.2 0.0 5.1e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EWM20933.1 - 6.2e-11 42.4 0.0 1e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EWM20934.1 - 9.5e-11 41.8 0.0 1.6e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EWM20934.1 - 0.0047 18.0 0.0 0.017 16.2 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase CN_hydrolase PF00795.22 EWM20935.1 - 2e-33 115.8 0.0 2.8e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 EWM20935.1 - 2.2e-18 66.2 0.0 8.6e-08 31.6 0.0 3.4 2 2 0 2 2 2 2 NAD synthase DnaJ PF00226.31 EWM20936.1 - 3.8e-25 87.8 0.0 6e-25 87.1 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain FSA_C PF10479.9 EWM20936.1 - 0.87 7.6 6.6 1.2 7.2 6.6 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Catalase PF00199.19 EWM20937.1 - 9e-194 643.9 0.0 1.1e-193 643.6 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EWM20937.1 - 4.9e-20 71.5 0.6 1.4e-19 70.0 0.3 1.9 2 0 0 2 2 2 1 Catalase-related immune-responsive Cytochrom_B561 PF03188.16 EWM20938.1 - 3.9e-19 69.1 9.1 3.9e-19 69.1 9.1 2.0 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DUF420 PF04238.12 EWM20938.1 - 0.00084 19.6 0.4 0.00084 19.6 0.4 2.7 3 1 0 3 3 3 1 Protein of unknown function (DUF420) DUF4079 PF13301.6 EWM20938.1 - 0.013 15.7 6.1 0.013 15.7 6.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) YrhC PF14143.6 EWM20938.1 - 5.6 7.1 7.7 0.35 11.0 0.3 2.7 2 1 1 3 3 3 0 YrhC-like protein Cytochrom_B561 PF03188.16 EWM20939.1 - 4.5e-19 68.9 9.4 4.5e-19 68.9 9.4 2.2 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DUF420 PF04238.12 EWM20939.1 - 0.00075 19.8 0.3 0.00075 19.8 0.3 2.8 3 1 0 3 3 3 1 Protein of unknown function (DUF420) DUF4079 PF13301.6 EWM20939.1 - 0.016 15.4 6.3 0.016 15.4 6.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) YrhC PF14143.6 EWM20939.1 - 5 7.3 7.8 0.33 11.1 0.3 2.8 2 1 1 3 3 3 0 YrhC-like protein Myb_DNA-binding PF00249.31 EWM20940.1 - 3.1e-12 46.5 0.3 5e-12 45.8 0.3 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EWM20940.1 - 0.00011 22.3 0.1 0.00019 21.6 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EWM20940.1 - 0.032 14.1 0.1 0.053 13.4 0.1 1.3 1 0 0 1 1 1 0 Myb DNA-binding like Neur_chan_memb PF02932.16 EWM20941.1 - 0.061 13.4 1.5 0.16 12.0 0.2 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DSPn PF14671.6 EWM20942.1 - 6e-48 162.9 0.2 1.4e-47 161.7 0.1 1.7 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EWM20942.1 - 5.6e-14 52.1 0.0 2.1e-13 50.2 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EWM20942.1 - 1.5e-05 25.1 0.0 3.6e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 EWM20942.1 - 0.00016 21.3 0.0 0.00033 20.3 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EWM20942.1 - 0.0078 16.2 0.3 0.041 13.8 0.0 2.0 2 0 0 2 2 2 1 Tyrosine phosphatase family Mito_carr PF00153.27 EWM20943.1 - 4.9e-27 93.7 4.8 3.5e-14 52.5 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 EWM20944.1 - 2.5e-24 85.0 3.7 2e-14 53.2 0.1 3.0 3 0 0 3 3 3 2 Mitochondrial carrier protein Sigma70_r2 PF04542.14 EWM20947.1 - 5.7e-13 48.4 0.0 1.2e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r3 PF04539.16 EWM20947.1 - 0.031 14.4 1.6 0.064 13.4 0.2 2.1 2 0 0 2 2 2 0 Sigma-70 region 3 GCK PF07802.11 EWM20948.1 - 2.7e-07 30.9 0.1 3.7e-07 30.5 0.1 1.2 1 0 0 1 1 1 1 GCK domain CX9C PF16860.5 EWM20948.1 - 0.00058 19.8 0.0 0.0015 18.5 0.0 1.7 1 1 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Myb_DNA-binding PF00249.31 EWM20949.1 - 2.7e-40 136.3 7.5 1.9e-14 53.6 0.7 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EWM20949.1 - 1.2e-32 111.9 1.1 1.8e-13 50.5 0.0 3.6 2 1 2 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EWM20949.1 - 0.0014 18.5 0.1 0.0053 16.6 0.0 2.0 2 0 0 2 2 2 1 Myb DNA-binding like Rap1_C PF11626.8 EWM20949.1 - 0.003 17.6 0.8 1.1 9.3 0.1 3.2 1 1 2 3 3 3 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 EWM20949.1 - 0.17 12.3 1.1 2 8.9 0.2 2.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Dimer_Tnp_hAT PF05699.14 EWM20950.1 - 4.6e-10 39.2 0.9 2.2e-09 36.9 0.2 2.4 2 1 0 2 2 2 1 hAT family C-terminal dimerisation region DUF2390 PF09523.10 EWM20950.1 - 1.8 8.9 5.6 5.8 7.3 0.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2390) CIAPIN1 PF05093.13 EWM20951.1 - 3.2e-16 59.7 17.7 6.6e-14 52.2 17.7 2.4 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis TPR_1 PF00515.28 EWM20952.1 - 0.00027 20.6 0.0 0.0098 15.7 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EWM20952.1 - 0.00039 21.0 0.1 0.00099 19.7 0.0 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EWM20952.1 - 0.00081 19.3 0.3 0.015 15.4 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EWM20952.1 - 0.0085 16.1 0.1 0.32 11.1 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EWM20952.1 - 0.026 15.0 0.0 0.036 14.6 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 EWM20952.1 - 0.034 14.3 0.0 0.15 12.3 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EWM20952.1 - 0.074 13.3 0.0 0.16 12.3 0.0 1.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EWM20952.1 - 0.075 12.9 0.2 0.15 12.0 0.2 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat PPR PF01535.20 EWM20952.1 - 0.094 13.0 0.2 0.54 10.6 0.0 2.2 2 0 0 2 2 2 0 PPR repeat ketoacyl-synt PF00109.26 EWM20954.1 - 7.1e-05 22.5 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KH_1 PF00013.29 EWM20955.1 - 1.1e-15 57.2 1.4 3.9e-09 36.2 0.2 2.3 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 EWM20955.1 - 0.00085 19.2 0.2 0.26 11.2 0.0 2.5 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 EWM20955.1 - 0.0011 18.8 2.9 0.61 9.9 0.0 2.4 2 0 0 2 2 2 2 KH domain DUF1180 PF06679.12 EWM20957.1 - 0.017 15.5 0.5 0.029 14.8 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) OCD_Mu_crystall PF02423.15 EWM20961.1 - 0.005 15.8 0.0 0.0058 15.6 0.0 1.1 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family dCMP_cyt_deam_1 PF00383.23 EWM20962.1 - 1.6e-06 27.9 0.1 2.7e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EWM20962.1 - 3e-05 23.8 0.0 5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 EWM20962.1 - 0.022 14.8 0.3 0.073 13.1 0.0 1.9 2 0 0 2 2 2 0 Bd3614-like deaminase Glyco_transf_17 PF04724.13 EWM20967.1 - 1.1e-32 113.4 0.0 1.4e-32 113.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 17 TMEM61 PF15105.6 EWM20967.1 - 0.011 15.6 0.0 0.083 12.7 0.0 1.9 2 0 0 2 2 2 0 TMEM61 protein family ADH_N_assoc PF13823.6 EWM20967.1 - 0.44 10.5 1.9 1.3 9.0 1.9 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated CD36 PF01130.21 EWM20969.1 - 0.14 10.7 0.0 0.17 10.3 0.0 1.0 1 0 0 1 1 1 0 CD36 family CD36 PF01130.21 EWM20970.1 - 1.2e-10 40.6 0.0 7e-08 31.4 0.0 2.2 2 0 0 2 2 2 2 CD36 family Fasciclin PF02469.22 EWM20973.1 - 1.3e-18 67.4 0.0 1.8e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain DUF2064 PF09837.9 EWM20974.1 - 8.2e-28 96.7 0.5 1.6e-27 95.8 0.5 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2064) NTP_transf_3 PF12804.7 EWM20974.1 - 0.027 14.8 0.1 0.043 14.2 0.1 1.4 1 0 0 1 1 1 0 MobA-like NTP transferase domain RRM_1 PF00076.22 EWM20975.1 - 1.7e-07 30.9 0.0 3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) F-box-like PF12937.7 EWM20975.1 - 7.3e-07 29.0 0.1 7.3e-07 29.0 0.1 3.8 4 0 0 4 4 4 1 F-box-like LRR_4 PF12799.7 EWM20975.1 - 1.7e-05 25.1 13.2 1.3 9.6 1.3 5.7 3 1 4 8 8 8 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EWM20975.1 - 0.00086 19.2 15.4 2.3 8.5 0.1 7.5 8 1 0 8 8 8 2 Leucine Rich repeat F-box PF00646.33 EWM20975.1 - 0.098 12.6 0.0 0.098 12.6 0.0 3.8 5 0 0 5 5 5 0 F-box domain LRR_1 PF00560.33 EWM20975.1 - 0.7 10.7 17.8 0.41 11.4 0.3 6.3 7 0 0 7 7 7 0 Leucine Rich Repeat RPAP2_Rtr1 PF04181.13 EWM20977.1 - 7.7e-10 39.0 0.0 1.5e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Rtr1/RPAP2 family Radical_SAM PF04055.21 EWM20978.1 - 0.027 14.8 0.1 0.034 14.5 0.1 1.1 1 0 0 1 1 1 0 Radical SAM superfamily TPR_1 PF00515.28 EWM20982.1 - 1.9e-24 84.4 6.5 9e-10 38.0 0.2 5.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 EWM20982.1 - 9.6e-22 75.3 10.9 5.4e-10 38.6 0.8 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 EWM20982.1 - 2.8e-19 68.5 6.9 1e-05 25.1 0.1 4.4 2 1 2 4 4 4 4 TPR repeat TPR_8 PF13181.6 EWM20982.1 - 2.4e-16 58.5 1.4 2.3e-06 27.4 0.0 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EWM20982.1 - 3e-16 58.7 14.2 0.00014 22.4 0.1 5.4 4 1 2 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 EWM20982.1 - 4.3e-16 59.3 14.7 1.2e-09 38.7 3.8 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 EWM20982.1 - 1.6e-12 46.9 2.6 0.0071 16.7 0.1 5.1 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EWM20982.1 - 2.5e-11 42.8 11.8 8.9e-06 25.4 0.1 5.6 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EWM20982.1 - 2.5e-11 43.9 9.2 2.3e-06 28.0 0.4 3.8 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 EWM20982.1 - 4.9e-11 42.6 13.1 1.1e-07 31.9 1.6 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EWM20982.1 - 6.7e-11 42.3 5.1 5.6e-07 29.8 2.1 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EWM20982.1 - 3.6e-07 30.4 3.9 0.22 12.3 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 EWM20982.1 - 2.3e-06 27.3 11.3 0.0059 16.4 1.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.6 EWM20982.1 - 0.00016 21.9 2.0 0.11 12.8 0.1 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EWM20982.1 - 0.0031 17.7 1.8 0.94 9.8 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 EWM20982.1 - 0.0071 16.4 0.5 5.1 7.3 0.0 3.8 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_15 PF13429.6 EWM20982.1 - 0.032 13.5 4.9 23 4.1 0.0 2.9 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 EWM20982.1 - 0.042 14.5 0.3 0.042 14.5 0.3 4.0 5 0 0 5 5 3 0 Tetratricopeptide repeat ChAPs PF09295.10 EWM20982.1 - 0.047 12.7 0.2 9.2 5.2 0.1 2.8 2 1 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) BTAD PF03704.17 EWM20982.1 - 0.06 13.8 2.4 1 9.8 0.1 2.8 3 1 0 3 3 3 0 Bacterial transcriptional activator domain Wzy_C_2 PF11846.8 EWM20982.1 - 0.061 13.3 0.1 0.12 12.3 0.1 1.5 1 1 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal NYD-SP12_N PF15015.6 EWM20982.1 - 0.075 11.4 0.0 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal Fis1_TPR_C PF14853.6 EWM20982.1 - 0.084 13.0 0.4 0.35 11.0 0.2 2.1 2 0 0 2 2 1 0 Fis1 C-terminal tetratricopeptide repeat XPC-binding PF09280.11 EWM20982.1 - 0.086 12.6 0.0 7.8 6.3 0.0 3.1 3 0 0 3 3 3 0 XPC-binding domain Retinal PF15449.6 EWM20983.1 - 2.8 5.6 8.7 3.3 5.4 8.7 1.1 1 0 0 1 1 1 0 Retinal protein G_glu_transpept PF01019.21 EWM20984.1 - 1.2e-140 469.7 0.0 1.4e-140 469.5 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF2378 PF09536.10 EWM20984.1 - 0.11 12.4 0.6 2.3 8.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2378) TPR_16 PF13432.6 EWM20985.1 - 1.2 9.9 11.3 0.62 10.7 0.5 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 EWM20985.1 - 1.6 9.7 5.2 18 6.5 0.1 4.1 3 2 1 4 4 4 0 Tetratricopeptide repeat RRM_1 PF00076.22 EWM20986.1 - 2.1e-21 75.5 0.0 2.8e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EWM20986.1 - 3.8e-05 23.7 0.0 5.4e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.6 EWM20986.1 - 0.00027 20.9 0.0 0.00043 20.2 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EWM20986.1 - 0.0085 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 EWM20986.1 - 0.015 15.4 0.1 0.024 14.7 0.1 1.4 1 1 0 1 1 1 0 Limkain b1 SNARE_assoc PF09335.11 EWM20987.1 - 9.1e-13 48.7 5.4 9.1e-13 48.7 5.4 2.4 2 1 0 2 2 2 1 SNARE associated Golgi protein CCB2_CCB4 PF11152.8 EWM20989.1 - 1.2e-05 24.7 0.1 0.0002 20.7 0.1 2.2 1 1 0 1 1 1 1 Cofactor assembly of complex C subunit B, CCB2/CCB4 Thioesterase PF00975.20 EWM20990.1 - 1.1e-19 71.5 0.0 1.6e-19 71.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.20 EWM20990.1 - 0.00093 18.9 0.0 1.4 8.5 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EWM20990.1 - 0.0018 17.6 0.0 0.38 10.0 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EWM20990.1 - 0.0037 17.9 0.0 0.02 15.5 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family XRCC4 PF06632.12 EWM20991.1 - 1.7e-08 33.8 0.0 2.1e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 HIP1_clath_bdg PF16515.5 EWM20991.1 - 0.16 12.6 1.4 0.26 11.9 1.4 1.3 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Myb_DNA-binding PF00249.31 EWM20993.1 - 1.5e-36 124.3 9.2 3.7e-14 52.6 0.2 3.6 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EWM20993.1 - 1.9e-30 104.9 1.9 8.8e-14 51.5 0.9 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 EWM20993.1 - 0.0046 17.0 0.0 18 5.4 0.0 3.4 3 0 0 3 3 3 1 SLIDE Rap1_C PF11626.8 EWM20993.1 - 0.19 11.8 4.9 13 5.9 0.3 4.1 3 1 1 4 4 4 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain V-SNARE_C PF12352.8 EWM20996.1 - 7.5e-07 29.3 0.8 8.8e-07 29.1 0.8 1.1 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Gp_dh_C PF02800.20 EWM20997.1 - 1.3e-65 219.8 0.0 1.8e-65 219.3 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EWM20997.1 - 5.8e-38 129.3 0.1 1.8e-37 127.7 0.1 1.9 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 EWM20997.1 - 0.058 13.5 0.2 0.32 11.1 0.0 2.3 2 1 1 3 3 3 0 Dihydrodipicolinate reductase, N-terminus DUF2187 PF09953.9 EWM20997.1 - 0.17 11.9 2.6 48 4.1 0.1 3.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2187) Sec15 PF04091.12 EWM20998.1 - 6e-35 121.2 0.0 1.2e-34 120.2 0.0 1.4 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like DIL PF01843.19 EWM20998.1 - 0.059 13.7 0.0 0.23 11.7 0.0 2.1 1 0 0 1 1 1 0 DIL domain FlbT PF07378.11 EWM20998.1 - 0.15 12.1 0.4 0.97 9.5 0.2 2.2 2 0 0 2 2 2 0 Flagellar protein FlbT DUF1214 PF06742.11 EWM20999.1 - 1.2e-06 29.0 0.0 4.8e-05 23.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1214) GYF PF02213.16 EWM21000.1 - 3e-17 62.0 0.3 7.4e-17 60.8 0.3 1.7 1 0 0 1 1 1 1 GYF domain APH PF01636.23 EWM21001.1 - 2.6e-38 132.3 0.1 3.4e-37 128.7 0.1 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Hydrolase PF00702.26 EWM21001.1 - 2.9e-07 31.0 0.0 1.8e-06 28.4 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase RIO1 PF01163.22 EWM21001.1 - 4.1e-05 23.3 0.0 0.0009 18.9 0.0 2.3 2 0 0 2 2 2 1 RIO1 family EcKinase PF02958.20 EWM21001.1 - 6.7e-05 22.3 0.0 0.00014 21.3 0.0 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase HAD_2 PF13419.6 EWM21001.1 - 0.00015 21.9 0.0 0.00033 20.8 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 EWM21001.1 - 0.04 14.3 0.1 0.37 11.2 0.1 2.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Choline_kinase PF01633.20 EWM21001.1 - 0.16 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.11 EWM21001.1 - 0.24 10.2 0.0 0.55 9.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) V-SNARE_C PF12352.8 EWM21002.1 - 0.016 15.5 0.3 0.25 11.7 0.0 2.3 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus PhageP22-tail PF09251.10 EWM21003.1 - 0.037 12.4 0.0 0.049 12.0 0.0 1.1 1 0 0 1 1 1 0 Salmonella phage P22 tail-spike CDP-OH_P_transf PF01066.21 EWM21004.1 - 5e-17 62.4 1.0 5e-17 62.4 1.0 2.3 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase TMEM40 PF15817.5 EWM21004.1 - 0.084 12.6 1.2 5.8 6.7 0.1 2.3 2 0 0 2 2 2 0 Transmembrane protein 40 family Complex1_LYR PF05347.15 EWM21005.1 - 1.3e-08 34.7 0.7 3.9e-08 33.2 0.1 1.9 2 0 0 2 2 2 1 Complex 1 protein (LYR family) DUF1068 PF06364.12 EWM21005.1 - 0.0066 16.3 0.7 0.015 15.2 0.6 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1068) Complex1_LYR_2 PF13233.6 EWM21005.1 - 0.021 15.6 0.6 0.034 14.9 0.6 1.5 1 1 0 1 1 1 0 Complex1_LYR-like CagY_M PF07337.11 EWM21005.1 - 0.37 10.5 2.0 1.2 8.8 0.8 2.2 2 0 0 2 2 2 0 DC-EC Repeat DUF1997 PF09366.10 EWM21006.1 - 1.5e-15 57.7 0.1 1.4e-10 41.5 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1997) Gp_dh_C PF02800.20 EWM21007.1 - 2.2e-68 228.8 0.1 3.3e-68 228.3 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EWM21007.1 - 3e-34 117.4 0.0 7.6e-34 116.1 0.0 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EWM21007.1 - 0.0087 15.4 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.20 EWM21007.1 - 0.03 14.4 0.2 0.14 12.3 0.0 2.3 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Gp_dh_C PF02800.20 EWM21008.1 - 2.6e-68 228.6 0.1 3.9e-68 228.0 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EWM21008.1 - 3.6e-34 117.1 0.0 8.7e-34 115.9 0.0 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EWM21008.1 - 0.0097 15.3 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.20 EWM21008.1 - 0.035 14.2 0.2 0.16 12.1 0.0 2.2 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus C2 PF00168.30 EWM21009.1 - 4.9e-05 23.6 0.0 8.7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 C2 domain ABC1 PF03109.16 EWM21010.1 - 7.5e-23 81.0 0.0 1.2e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EWM21010.1 - 0.024 14.6 1.3 1.1 9.1 1.3 3.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family GCK PF07802.11 EWM21011.1 - 9e-13 48.5 0.2 1.8e-12 47.4 0.2 1.5 1 0 0 1 1 1 1 GCK domain AAA PF00004.29 EWM21012.1 - 6.5e-36 123.7 0.0 1.2e-28 100.2 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EWM21012.1 - 7.3e-11 42.7 5.5 0.0023 18.3 0.1 4.3 3 2 1 5 5 3 3 AAA ATPase domain AAA_lid_3 PF17862.1 EWM21012.1 - 4.7e-10 39.1 0.1 4.7e-10 39.1 0.1 3.5 4 0 0 4 4 3 1 AAA+ lid domain AAA_22 PF13401.6 EWM21012.1 - 1.4e-07 31.9 1.0 0.28 11.5 0.0 4.2 3 1 1 4 4 4 2 AAA domain IstB_IS21 PF01695.17 EWM21012.1 - 2.9e-06 27.1 0.0 0.0019 17.9 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_5 PF07728.14 EWM21012.1 - 1.6e-05 24.9 0.6 0.16 11.9 0.1 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EWM21012.1 - 3.1e-05 24.1 0.1 0.056 13.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 EWM21012.1 - 7.3e-05 22.1 0.2 0.037 13.2 0.0 2.1 2 0 0 2 2 2 2 TIP49 P-loop domain TsaE PF02367.17 EWM21012.1 - 0.00012 22.1 0.1 0.043 13.8 0.1 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 EWM21012.1 - 0.00012 21.8 0.1 0.21 11.3 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain PhoH PF02562.16 EWM21012.1 - 0.0002 20.9 0.2 0.17 11.3 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein DUF815 PF05673.13 EWM21012.1 - 0.00027 20.2 0.0 0.078 12.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_23 PF13476.6 EWM21012.1 - 0.0015 19.1 0.0 0.026 15.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EWM21012.1 - 0.0015 19.1 0.0 0.81 10.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EWM21012.1 - 0.002 17.6 1.4 0.086 12.2 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EWM21012.1 - 0.0024 17.5 8.6 0.47 10.0 0.3 4.4 2 2 2 4 4 4 1 AAA domain AAA_29 PF13555.6 EWM21012.1 - 0.0026 17.5 0.1 0.2 11.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EWM21012.1 - 0.0069 15.7 0.4 0.31 10.3 0.1 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_7 PF12775.7 EWM21012.1 - 0.0074 15.8 0.0 1.5 8.3 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region Vps4_C PF09336.10 EWM21012.1 - 0.011 15.8 0.0 0.029 14.3 0.0 1.7 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain AAA_24 PF13479.6 EWM21012.1 - 0.012 15.4 0.0 0.38 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EWM21012.1 - 0.014 15.7 1.4 9.5 6.6 0.1 3.3 3 0 0 3 3 3 0 AAA domain Sigma54_activat PF00158.26 EWM21012.1 - 0.018 14.8 0.0 4.4 7.0 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain NACHT PF05729.12 EWM21012.1 - 0.018 14.9 3.3 0.59 10.0 0.2 3.3 3 0 0 3 3 3 0 NACHT domain RNA_helicase PF00910.22 EWM21012.1 - 0.029 14.7 0.0 3.3 8.1 0.0 2.3 2 0 0 2 2 2 0 RNA helicase ATPase_2 PF01637.18 EWM21012.1 - 0.03 14.2 0.0 8 6.3 0.0 3.0 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_17 PF13207.6 EWM21012.1 - 0.035 14.5 0.0 0.42 11.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 EWM21012.1 - 0.054 13.2 0.6 0.63 9.7 0.1 2.3 2 0 0 2 2 2 0 Cytidylate kinase AAA_3 PF07726.11 EWM21012.1 - 0.086 12.7 0.0 2.2 8.1 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EWM21012.1 - 0.1 12.3 5.2 2.5 7.8 0.1 2.9 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.22 EWM21012.1 - 0.11 11.6 0.0 16 4.6 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain AAA_28 PF13521.6 EWM21012.1 - 0.13 12.5 0.1 17 5.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EWM21012.1 - 0.17 11.7 0.0 10 5.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EWM21012.1 - 0.17 12.4 0.2 21 5.6 0.0 3.0 3 0 0 3 3 3 0 ABC transporter T2SSE PF00437.20 EWM21012.1 - 0.23 10.5 0.0 3.1 6.8 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF2075 PF09848.9 EWM21012.1 - 0.93 8.7 1.6 5.8 6.1 0.1 2.5 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2075) DUF3605 PF12239.8 EWM21014.1 - 0.00018 21.9 1.7 0.00043 20.6 1.7 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) DUF3605 PF12239.8 EWM21015.1 - 0.00013 22.3 1.8 0.00033 21.0 1.8 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) Brix PF04427.18 EWM21016.1 - 3e-32 112.3 0.0 4.1e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 Brix domain PPP4R2 PF09184.11 EWM21016.1 - 9.3 5.7 12.1 15 5.1 12.1 1.3 1 0 0 1 1 1 0 PPP4R2 Glyco_transf_20 PF00982.21 EWM21018.1 - 2.7e-178 593.5 0.0 3.3e-178 593.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EWM21018.1 - 2.2e-63 213.5 0.0 3.5e-63 212.9 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 EWM21018.1 - 0.061 13.0 0.0 7 6.3 0.0 2.3 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase FlxA PF14282.6 EWM21018.1 - 0.12 12.4 3.3 0.29 11.1 3.3 1.6 1 0 0 1 1 1 0 FlxA-like protein WD40 PF00400.32 EWM21019.1 - 5.9e-10 39.6 3.4 0.0013 19.5 0.1 5.3 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM21019.1 - 1.1e-05 25.6 0.0 0.0045 17.2 0.0 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Gpi1 PF05024.15 EWM21020.1 - 1.6e-24 87.0 5.5 2.7e-21 76.5 0.2 2.3 3 0 0 3 3 3 2 N-acetylglucosaminyl transferase component (Gpi1) Bap31 PF05529.12 EWM21023.1 - 4.4e-07 29.8 0.2 8e-07 29.0 0.2 1.4 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region DUF1772 PF08592.11 EWM21023.1 - 0.0049 17.2 0.0 0.012 16.0 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) WD40_alt PF14077.6 EWM21023.1 - 0.078 12.9 3.0 0.15 11.9 3.0 1.4 1 0 0 1 1 1 0 Alternative WD40 repeat motif Conotoxin PF02950.17 EWM21023.1 - 0.11 13.6 0.0 11 7.1 0.0 2.3 2 0 0 2 2 2 0 Conotoxin Baculo_11_kDa PF06143.11 EWM21023.1 - 0.3 10.7 1.0 6.7 6.4 0.0 2.5 3 0 0 3 3 3 0 Baculovirus 11 kDa family Phlebovirus_NSM PF07246.11 EWM21023.1 - 3.3 7.0 5.5 5.1 6.4 5.5 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Aquarius_N PF16399.5 EWM21024.1 - 3.9e-136 455.2 0.0 6.3e-136 454.5 0.0 1.3 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_11 PF13086.6 EWM21024.1 - 4.4e-26 92.2 0.3 1.2e-24 87.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.6 EWM21024.1 - 3.3e-25 88.9 0.0 6e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EWM21024.1 - 5.3e-07 30.1 0.0 8.2e-06 26.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EWM21024.1 - 2.9e-06 27.1 0.0 0.081 12.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 EWM21024.1 - 0.00026 21.0 0.0 0.00058 19.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.6 EWM21024.1 - 0.0015 18.4 0.1 0.0035 17.1 0.1 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DEAD PF00270.29 EWM21024.1 - 0.0025 17.6 0.0 0.0049 16.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase UvrD-helicase PF00580.21 EWM21024.1 - 0.0037 16.8 0.2 0.0095 15.5 0.0 1.7 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain PhoH PF02562.16 EWM21024.1 - 0.037 13.5 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EWM21024.1 - 0.049 14.1 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 EWM21024.1 - 0.16 11.0 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_22 PF13401.6 EWM21024.1 - 0.17 12.1 0.1 0.69 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain Lipase_3 PF01764.25 EWM21025.1 - 1.1e-14 54.5 0.0 1.7e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Pkinase PF00069.25 EWM21026.1 - 6.3e-41 140.5 0.0 7.8e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM21026.1 - 2.3e-16 59.9 0.0 1.1e-15 57.6 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EWM21026.1 - 5.8e-06 26.4 0.1 1.4e-05 25.1 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EWM21026.1 - 0.0081 15.8 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EWM21026.1 - 0.023 14.0 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4242 PF14026.6 EWM21026.1 - 0.16 12.2 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4242) Pkinase_fungal PF17667.1 EWM21026.1 - 0.18 10.5 0.0 0.32 9.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Ion_trans PF00520.31 EWM21027.1 - 2.3e-25 89.2 5.2 2.8e-25 89.0 5.2 1.1 1 0 0 1 1 1 1 Ion transport protein PapA_C PF16911.5 EWM21027.1 - 0.086 12.9 0.2 0.18 11.9 0.2 1.5 1 1 0 1 1 1 0 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus Ion_trans PF00520.31 EWM21028.1 - 1.2e-47 162.3 7.5 1.4e-47 162.0 7.5 1.0 1 0 0 1 1 1 1 Ion transport protein APH PF01636.23 EWM21029.1 - 0.012 15.5 1.0 0.047 13.6 0.2 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ribosomal_S16 PF00886.19 EWM21030.1 - 3.6e-27 94.2 0.0 5.7e-27 93.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 DUF5480 PF17576.2 EWM21031.1 - 0.05 13.6 0.1 0.28 11.2 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5480) Ank_2 PF12796.7 EWM21034.1 - 3.8e-15 56.3 0.0 2.8e-07 31.0 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EWM21034.1 - 3.3e-13 49.6 0.2 0.00039 20.7 0.1 4.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EWM21034.1 - 4.2e-13 49.1 0.6 1.8e-05 25.0 0.1 4.7 4 1 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EWM21034.1 - 5.2e-12 46.0 0.0 5.4e-05 23.7 0.1 3.8 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EWM21034.1 - 3.6e-10 39.2 0.1 0.0019 18.5 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat ETRAMP PF09716.10 EWM21035.1 - 0.053 13.6 0.0 0.092 12.8 0.0 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) MFS_2 PF13347.6 EWM21035.1 - 0.078 11.5 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein GTP_EFTU PF00009.27 EWM21037.1 - 1.3e-32 112.9 1.6 8.8e-31 107.0 1.6 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EWM21037.1 - 3e-28 98.0 3.9 8.3e-28 96.6 3.9 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 EWM21037.1 - 1.3e-11 44.6 0.1 3.5e-11 43.2 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF2_N PF04760.15 EWM21037.1 - 5.8e-09 35.6 0.0 1.4e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region GTP_EFTU_D2 PF03144.25 EWM21037.1 - 3.4e-06 27.4 7.3 0.00025 21.4 0.3 3.4 3 0 0 3 3 3 2 Elongation factor Tu domain 2 FeoB_N PF02421.18 EWM21037.1 - 0.00014 21.5 0.5 0.001 18.6 0.1 2.4 2 1 0 2 2 2 1 Ferrous iron transport protein B SRPRB PF09439.10 EWM21037.1 - 0.00015 21.2 0.0 0.00063 19.2 0.0 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EWM21037.1 - 0.00035 20.5 1.4 0.057 13.3 0.1 2.6 1 1 1 2 2 2 2 RsgA GTPase Ras PF00071.22 EWM21037.1 - 0.0013 18.3 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 Ras family MMR_HSR1_Xtn PF16897.5 EWM21037.1 - 0.0014 18.7 0.0 0.0033 17.4 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Roc PF08477.13 EWM21037.1 - 0.022 15.0 0.0 0.041 14.1 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 EWM21037.1 - 0.092 12.5 0.0 0.26 11.0 0.0 1.8 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Pkinase PF00069.25 EWM21038.1 - 6.1e-12 45.5 0.0 9e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM21038.1 - 0.014 14.6 0.0 0.032 13.5 0.0 1.5 2 0 0 2 2 2 0 Protein tyrosine kinase DUF4431 PF14485.6 EWM21039.1 - 0.12 12.2 0.1 0.24 11.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) SET PF00856.28 EWM21040.1 - 2e-15 57.6 0.0 9.8e-15 55.3 0.0 2.0 1 1 0 1 1 1 1 SET domain AWS PF17907.1 EWM21040.1 - 9.7e-07 28.7 4.3 9.7e-07 28.7 4.3 2.1 2 0 0 2 2 2 1 AWS domain zf-RING_4 PF14570.6 EWM21040.1 - 0.091 12.6 2.1 0.42 10.5 0.1 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Epimerase PF01370.21 EWM21041.1 - 8.7e-12 45.0 0.0 1.7e-11 44.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EWM21041.1 - 1.7e-07 30.9 0.0 9.4e-05 21.9 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EWM21041.1 - 6.7e-07 29.4 0.0 0.0053 16.7 0.0 2.6 2 1 0 2 2 2 2 NAD(P)H-binding 3Beta_HSD PF01073.19 EWM21041.1 - 0.00028 20.0 0.0 0.11 11.5 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family SUZ PF12752.7 EWM21041.1 - 0.00055 20.7 1.1 0.28 12.0 0.0 2.6 2 0 0 2 2 2 2 SUZ domain RmlD_sub_bind PF04321.17 EWM21041.1 - 0.012 14.7 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_4 PF07993.12 EWM21041.1 - 0.033 13.3 0.0 0.9 8.7 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein NmrA PF05368.13 EWM21041.1 - 0.072 12.6 0.0 0.64 9.5 0.0 2.0 2 0 0 2 2 2 0 NmrA-like family ABC2_membrane PF01061.24 EWM21043.1 - 7.2e-13 48.4 12.3 7.7e-13 48.3 12.3 1.0 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 EWM21043.1 - 0.15 11.2 12.9 0.19 10.8 12.9 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein ABC_tran PF00005.27 EWM21044.1 - 9.3e-17 61.8 0.0 1.3e-16 61.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 EWM21044.1 - 9.7e-12 44.7 20.7 1.3e-11 44.3 20.7 1.2 1 0 0 1 1 1 1 ABC-2 type transporter AAA_29 PF13555.6 EWM21044.1 - 0.00023 20.9 0.3 0.00046 19.9 0.3 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 EWM21044.1 - 0.00073 19.2 0.3 0.0012 18.5 0.3 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EWM21044.1 - 0.0032 17.4 0.1 0.0082 16.1 0.2 1.5 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EWM21044.1 - 0.012 16.0 0.1 0.02 15.3 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain ABC2_membrane_3 PF12698.7 EWM21044.1 - 0.012 14.7 9.8 0.015 14.4 9.8 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_30 PF13604.6 EWM21044.1 - 0.014 15.1 0.1 0.021 14.5 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EWM21044.1 - 0.064 13.5 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EWM21044.1 - 0.079 13.1 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EWM21044.1 - 0.099 12.9 0.1 0.16 12.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 EWM21044.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 EWM21044.1 - 0.13 12.8 0.1 0.21 12.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 EWM21044.1 - 0.14 12.2 0.3 0.23 11.5 0.1 1.5 2 0 0 2 2 1 0 Dynamin family AAA_24 PF13479.6 EWM21044.1 - 0.18 11.5 0.1 0.27 10.9 0.1 1.2 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 EWM21044.1 - 0.29 10.5 0.1 0.56 9.6 0.1 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain NUDIX PF00293.28 EWM21045.1 - 0.003 17.6 0.2 0.0065 16.5 0.2 1.6 1 0 0 1 1 1 1 NUDIX domain Pkinase PF00069.25 EWM21046.1 - 1.2e-31 110.1 0.0 1.6e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM21046.1 - 3.5e-16 59.3 0.0 5.7e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EWM21046.1 - 0.00086 18.2 0.0 0.0013 17.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EWM21048.1 - 3.1e-23 82.5 0.0 1.4e-22 80.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM21048.1 - 5.6e-10 38.9 0.0 1.9e-07 30.7 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EWM21048.1 - 0.097 11.4 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Herpes_capsid PF06112.11 EWM21048.1 - 0.96 9.5 5.9 0.25 11.4 1.9 2.0 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein DDOST_48kD PF03345.14 EWM21049.1 - 0.16 10.8 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase 48 kDa subunit beta Spem1 PF15670.5 EWM21050.1 - 0.12 11.9 4.4 0.15 11.6 4.4 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 NIF PF03031.18 EWM21051.1 - 2.8e-39 134.4 0.0 5.2e-39 133.5 0.0 1.4 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 EWM21051.1 - 0.055 13.9 0.1 0.14 12.6 0.1 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 EWM21052.1 - 2.3e-29 102.6 0.0 2e-14 53.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EWM21052.1 - 5.7e-10 38.9 0.0 1.6e-06 27.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EWM21052.1 - 2.4e-07 29.9 0.0 3.9e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EWM21052.1 - 2.6e-06 27.0 0.0 4.3e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EWM21052.1 - 0.033 14.1 0.0 0.079 12.9 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family EcKinase PF02958.20 EWM21052.1 - 0.04 13.2 0.0 0.064 12.6 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase SET PF00856.28 EWM21053.1 - 5.3e-14 52.9 0.0 1.6e-13 51.4 0.0 1.9 2 1 0 2 2 2 1 SET domain Bac_GH3_C PF18034.1 EWM21054.1 - 0.053 13.3 0.0 0.071 12.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial Glycosyl hydrolase family 3 C-terminal domain NRIP1_repr_1 PF15687.5 EWM21056.1 - 0.029 14.1 0.5 0.038 13.7 0.5 1.1 1 0 0 1 1 1 0 Nuclear receptor-interacting protein 1 repression 1 DUF390 PF04094.14 EWM21056.1 - 0.029 12.7 0.1 0.037 12.3 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF390) GATase PF00117.28 EWM21057.1 - 0.00013 21.8 0.0 0.00016 21.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Pentapeptide PF00805.22 EWM21058.1 - 2.6e-17 62.1 2.7 3.7e-10 39.2 0.5 2.4 1 1 0 2 2 2 2 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 EWM21058.1 - 6.5e-14 51.8 4.7 3.5e-07 30.3 0.3 2.1 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.6 EWM21058.1 - 4.2e-10 39.7 0.4 1.1e-09 38.4 0.4 1.6 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) DUF5020 PF16412.5 EWM21058.1 - 0.13 12.1 0.0 0.15 11.9 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5020) Peptidase_S49_N PF08496.10 EWM21062.1 - 0.093 12.8 3.9 0.17 11.9 3.9 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3006 PF11213.8 EWM21062.1 - 0.12 12.6 2.1 6.6 7.0 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) DUF724 PF05266.14 EWM21062.1 - 0.12 12.2 5.4 0.19 11.6 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Phlebovirus_NSM PF07246.11 EWM21062.1 - 1 8.7 4.9 1.5 8.1 4.9 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M AP1AR PF15745.5 EWM21062.1 - 2.8 7.5 7.6 4.1 7.0 7.6 1.2 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein DUF1990 PF09348.10 EWM21063.1 - 2.5e-15 56.8 3.3 6.2e-15 55.6 3.3 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1990) FAD_binding_4 PF01565.23 EWM21066.1 - 1.1e-10 41.4 0.0 1.4e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SCAN PF02023.17 EWM21066.1 - 0.032 14.1 0.0 0.25 11.2 0.0 2.0 2 0 0 2 2 2 0 SCAN domain Rgp1 PF08737.10 EWM21068.1 - 3.7e-07 29.7 0.1 5.1e-07 29.2 0.1 1.2 1 0 0 1 1 1 1 Rgp1 DUF523 PF04463.12 EWM21068.1 - 0.037 14.1 0.0 0.11 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF523) Hydrolase_4 PF12146.8 EWM21069.1 - 2.3e-12 46.7 0.0 9e-12 44.8 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EWM21069.1 - 3.4e-12 47.4 2.1 3.4e-12 47.4 2.1 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EWM21069.1 - 1.3e-10 41.3 0.1 4.3e-10 39.7 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold CDC45 PF02724.14 EWM21070.1 - 1.6 6.9 3.8 1.6 6.9 3.8 1.0 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 EWM21070.1 - 3.6 7.2 8.7 1.7 8.3 6.7 1.5 2 0 0 2 2 2 0 FAM176 family DUF4637 PF15470.6 EWM21070.1 - 3.7 7.2 10.2 5.4 6.7 10.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) PRP38_assoc PF12871.7 EWM21070.1 - 5 7.8 17.3 11 6.7 17.4 1.6 1 1 1 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DNA_pol_phi PF04931.13 EWM21070.1 - 5.2 5.1 6.9 5.6 4.9 6.9 1.0 1 0 0 1 1 1 0 DNA polymerase phi TsaE PF02367.17 EWM21072.1 - 8.4e-23 80.7 0.0 1.3e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EWM21072.1 - 0.0047 16.8 0.1 0.0097 15.8 0.1 1.5 1 0 0 1 1 1 1 NACHT domain ATPase PF06745.13 EWM21072.1 - 0.0083 15.5 0.1 0.012 15.0 0.1 1.1 1 0 0 1 1 1 1 KaiC AAA_16 PF13191.6 EWM21072.1 - 0.019 15.3 0.0 0.03 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EWM21072.1 - 0.031 14.7 0.0 0.048 14.1 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EWM21072.1 - 0.08 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EWM21072.1 - 0.093 12.3 0.2 0.16 11.6 0.2 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EWM21072.1 - 0.13 11.9 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EWM21072.1 - 0.23 11.4 0.0 0.38 10.6 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Baculo_11_kDa PF06143.11 EWM21074.1 - 0.2 11.2 0.7 0.27 10.9 0.7 1.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family Alg6_Alg8 PF03155.15 EWM21075.1 - 2.3e-11 43.4 0.1 3.3e-11 42.9 0.1 1.2 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family NAD_binding_11 PF14833.6 EWM21078.1 - 7.6e-05 23.0 0.0 0.0001 22.5 0.0 1.2 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Transcrip_reg PF01709.20 EWM21079.1 - 1.9e-21 76.6 3.6 2.3e-21 76.3 3.6 1.1 1 0 0 1 1 1 1 Transcriptional regulator SIP1 PF04938.12 EWM21081.1 - 9.4e-09 35.3 0.0 2e-08 34.2 0.0 1.5 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) SIP1 PF04938.12 EWM21082.1 - 2.3e-22 79.8 0.0 2.7e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) FTHFS PF01268.19 EWM21084.1 - 1.1e-38 132.8 0.0 1.2e-38 132.7 0.0 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase Thioesterase PF00975.20 EWM21085.1 - 1e-23 84.7 0.0 2.9e-17 63.6 0.0 2.1 2 0 0 2 2 2 2 Thioesterase domain Abhydrolase_6 PF12697.7 EWM21085.1 - 4.8e-06 27.3 1.6 5.4e-06 27.2 0.2 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.13 EWM21085.1 - 0.0022 17.7 0.0 0.004 16.8 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 EWM21085.1 - 0.078 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EWM21085.1 - 0.085 12.7 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold AMP-binding PF00501.28 EWM21089.1 - 0.0039 15.9 0.0 0.0068 15.1 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme DUF2177 PF09945.9 EWM21091.1 - 3.8e-10 39.9 12.1 5.6e-09 36.1 12.1 2.0 1 1 0 1 1 1 1 Predicted membrane protein (DUF2177) YhfC PF10086.9 EWM21091.1 - 0.0057 16.0 1.2 0.13 11.6 0.6 2.1 2 0 0 2 2 2 2 YhfC intramembrane metalloprotease UQ_con PF00179.26 EWM21093.1 - 4e-43 146.4 0.0 4.9e-43 146.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EWM21093.1 - 0.0041 17.4 0.0 0.005 17.1 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 EWM21093.1 - 0.0068 16.1 0.0 0.0075 16.0 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EWM21093.1 - 0.044 13.6 0.1 0.064 13.1 0.1 1.3 1 0 0 1 1 1 0 UEV domain HIT PF01230.23 EWM21094.1 - 0.02 15.6 0.1 0.04 14.6 0.1 1.4 1 0 0 1 1 1 0 HIT domain Asp_protease PF09668.10 EWM21095.1 - 1.2e-59 199.5 0.2 1.9e-59 198.8 0.2 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EWM21095.1 - 1.1e-23 83.6 0.1 3.7e-23 81.9 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EWM21095.1 - 6.6e-10 39.5 0.1 2.2e-09 37.8 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease UBA PF00627.31 EWM21095.1 - 7.7e-07 28.9 0.7 1.9e-05 24.5 0.1 2.6 2 0 0 2 2 2 1 UBA/TS-N domain ubiquitin PF00240.23 EWM21095.1 - 1.8e-06 27.6 0.0 4.4e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family RVP_2 PF08284.11 EWM21095.1 - 0.00018 21.3 0.0 0.00032 20.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Rad60-SLD PF11976.8 EWM21095.1 - 0.00049 19.9 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RVP PF00077.20 EWM21095.1 - 0.0011 19.2 0.0 0.0032 17.7 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA_4 PF14555.6 EWM21095.1 - 0.05 13.4 0.1 0.59 10.0 0.0 2.3 2 0 0 2 2 2 0 UBA-like domain SchA_CurD PF04486.12 EWM21095.1 - 0.067 13.3 0.2 0.16 12.0 0.2 1.7 1 0 0 1 1 1 0 SchA/CurD like domain CDP-OH_P_transf PF01066.21 EWM21096.1 - 2.2e-13 50.8 0.0 1.1e-12 48.5 0.0 1.9 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase DUF4140 PF13600.6 EWM21097.1 - 0.097 13.1 2.7 0.17 12.3 2.7 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Atg14 PF10186.9 EWM21097.1 - 0.28 10.2 1.2 0.35 9.9 1.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GAS PF13851.6 EWM21097.1 - 0.29 10.5 6.3 0.4 10.0 6.3 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Vps5 PF09325.10 EWM21097.1 - 0.73 9.3 5.4 1 8.9 5.4 1.1 1 0 0 1 1 1 0 Vps5 C terminal like Methyltransf_25 PF13649.6 EWM21098.1 - 1.6e-06 28.7 0.0 3.8e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EWM21098.1 - 0.0001 22.2 0.0 0.00024 21.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM21098.1 - 0.0001 22.8 0.0 0.00023 21.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM21098.1 - 0.0057 16.5 0.0 0.0086 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EWM21098.1 - 0.0075 17.0 0.0 0.018 15.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EWM21098.1 - 0.017 14.7 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain TehB PF03848.14 EWM21098.1 - 0.017 14.5 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB GidB PF02527.15 EWM21098.1 - 0.086 12.1 0.0 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Rhodanese PF00581.20 EWM21098.1 - 0.1 13.1 0.0 0.29 11.7 0.0 1.7 1 1 0 1 1 1 0 Rhodanese-like domain Methyltransf_4 PF02390.17 EWM21098.1 - 0.17 11.3 0.0 0.44 10.0 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase SWIM PF04434.17 EWM21099.1 - 2.3e-05 24.0 0.8 2.3e-05 24.0 0.8 2.0 2 1 1 3 3 3 1 SWIM zinc finger AdoHcyase PF05221.17 EWM21100.1 - 1e-131 438.5 0.1 1.3e-131 438.2 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 EWM21100.1 - 1.6e-78 262.4 4.4 2.4e-78 261.8 4.4 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 EWM21100.1 - 5.4e-10 38.9 0.5 9.7e-10 38.1 0.5 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 EWM21100.1 - 0.00013 21.6 0.4 0.00026 20.6 0.4 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 EWM21100.1 - 0.00014 22.1 0.4 0.0059 16.9 0.2 2.8 2 1 0 2 2 2 1 TrkA-N domain Shikimate_DH PF01488.20 EWM21100.1 - 0.0034 17.5 0.4 0.0077 16.3 0.4 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.21 EWM21100.1 - 0.0084 15.9 0.2 0.016 15.0 0.2 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_7 PF13241.6 EWM21100.1 - 0.026 14.9 0.3 0.063 13.7 0.3 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.19 EWM21100.1 - 0.048 13.0 4.1 0.19 11.0 4.1 1.8 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Aminotran_1_2 PF00155.21 EWM21101.1 - 2.2e-39 135.7 0.0 3.1e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EWM21101.1 - 0.0027 16.7 0.0 0.0052 15.8 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 EWM21101.1 - 0.015 14.1 0.0 0.051 12.3 0.0 1.8 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain DegT_DnrJ_EryC1 PF01041.17 EWM21101.1 - 0.046 13.0 0.1 0.54 9.5 0.1 2.0 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family AP_endonuc_2 PF01261.24 EWM21104.1 - 7.2e-10 38.7 0.0 3.8e-06 26.5 0.0 2.3 1 1 1 2 2 2 2 Xylose isomerase-like TIM barrel CAF1 PF04857.20 EWM21105.1 - 3.8e-69 233.3 0.0 5.7e-69 232.7 0.0 1.3 1 0 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.20 EWM21105.1 - 0.00038 20.2 0.0 0.011 15.5 0.0 2.5 2 0 0 2 2 2 1 3'-5' exonuclease Inositol_P PF00459.25 EWM21106.1 - 1.9e-39 135.8 0.6 2.5e-39 135.4 0.6 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family Trp_ring PF18669.1 EWM21106.1 - 0.066 13.4 0.5 0.19 12.0 0.5 1.7 1 0 0 1 1 1 0 Trimeric autotransporter adhesin Trp ring domain Fcf1 PF04900.12 EWM21107.1 - 1e-12 48.3 0.1 3.1e-12 46.8 0.0 1.8 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 EWM21107.1 - 8.7e-08 32.5 0.1 2.4e-07 31.1 0.1 1.7 1 1 0 1 1 1 1 PIN like domain GFO_IDH_MocA PF01408.22 EWM21108.1 - 1.4e-21 77.5 0.0 2.4e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EWM21108.1 - 2.5e-07 30.7 0.0 4.7e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Mito_carr PF00153.27 EWM21109.1 - 1.4e-60 201.2 0.9 4.1e-21 74.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Sel1 PF08238.12 EWM21110.1 - 3.3e-05 24.4 0.8 0.32 11.7 0.0 3.6 3 0 0 3 3 3 3 Sel1 repeat adh_short PF00106.25 EWM21111.1 - 1.7e-29 102.7 0.1 1e-21 77.3 0.2 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EWM21111.1 - 1.3e-23 83.8 0.0 2.8e-22 79.4 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM21111.1 - 1.3e-09 38.2 0.5 1.9e-09 37.7 0.5 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EWM21111.1 - 0.0036 16.8 0.1 0.0052 16.3 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF2325 PF10087.9 EWM21111.1 - 0.063 13.4 0.1 0.1 12.8 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) GDP_Man_Dehyd PF16363.5 EWM21111.1 - 0.14 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Kelch_4 PF13418.6 EWM21112.1 - 1.8e-15 56.7 23.4 1.5e-06 28.1 0.2 6.3 4 2 2 6 6 6 4 Galactose oxidase, central domain zf-RING_2 PF13639.6 EWM21112.1 - 8.5e-14 51.6 3.8 1.4e-13 51.0 3.8 1.3 1 0 0 1 1 1 1 Ring finger domain Kelch_3 PF13415.6 EWM21112.1 - 4.7e-12 45.9 17.3 0.051 13.9 0.1 6.8 7 1 0 7 7 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 EWM21112.1 - 1.9e-10 40.6 9.4 0.028 14.7 0.0 6.3 5 1 1 6 6 6 4 Kelch motif zf-RING_11 PF17123.5 EWM21112.1 - 4e-09 36.0 1.6 7.8e-09 35.1 1.6 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 EWM21112.1 - 1.1e-08 34.8 1.7 1.8e-08 34.1 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Kelch_5 PF13854.6 EWM21112.1 - 3.6e-08 33.2 5.4 0.0076 16.2 0.0 6.0 6 0 0 6 6 6 1 Kelch motif Kelch_1 PF01344.25 EWM21112.1 - 6.4e-08 32.1 1.9 0.016 14.8 0.0 5.0 5 0 0 5 5 5 1 Kelch motif zf-C3HC4_2 PF13923.6 EWM21112.1 - 6.3e-07 29.1 4.1 1.2e-06 28.3 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Kelch_2 PF07646.15 EWM21112.1 - 9e-07 28.6 7.5 0.56 10.3 0.0 5.8 6 0 0 6 6 6 1 Kelch motif zf-rbx1 PF12678.7 EWM21112.1 - 4.9e-06 26.7 4.6 1.7e-05 25.0 4.6 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EWM21112.1 - 4.9e-06 26.5 1.1 8.7e-06 25.7 1.1 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EWM21112.1 - 0.00094 19.1 1.7 0.0015 18.5 1.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EWM21112.1 - 0.0014 18.4 2.3 0.0024 17.7 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EWM21112.1 - 0.002 18.0 2.4 0.0033 17.3 2.4 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EWM21112.1 - 0.0025 17.9 3.9 0.0044 17.2 3.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 EWM21112.1 - 0.0029 17.6 3.0 0.013 15.5 3.0 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EWM21112.1 - 0.0039 16.8 2.7 0.0067 16.0 2.7 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 EWM21112.1 - 0.015 15.6 2.3 0.025 14.9 2.3 1.4 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 EWM21112.1 - 0.082 13.0 2.9 0.18 11.9 2.9 1.6 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 EWM21112.1 - 0.1 12.8 3.6 0.48 10.6 3.6 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 EWM21112.1 - 0.27 11.1 2.7 0.46 10.4 2.7 1.4 1 0 0 1 1 1 0 PHD-finger COPIIcoated_ERV PF07970.12 EWM21113.1 - 3e-29 102.5 0.3 7.2e-29 101.2 0.1 1.7 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EWM21113.1 - 1.2e-27 96.1 0.7 9.1e-27 93.2 0.6 2.4 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Thioredoxin PF00085.20 EWM21113.1 - 3.9e-22 78.2 0.0 8.5e-22 77.1 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EWM21113.1 - 0.014 15.9 0.1 0.067 13.6 0.1 2.1 2 0 0 2 2 2 0 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EWM21113.1 - 0.064 13.6 0.0 0.19 12.1 0.0 1.9 1 0 0 1 1 1 0 Thioredoxin-like OST3_OST6 PF04756.13 EWM21113.1 - 0.087 12.2 0.7 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family TFIIS_C PF01096.18 EWM21114.1 - 1.5e-18 66.4 3.5 1.5e-18 66.4 3.5 2.4 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EWM21114.1 - 2.6e-07 30.4 3.4 2.6e-07 30.4 3.4 2.4 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 EWM21114.1 - 0.0051 16.7 8.7 0.019 14.9 0.4 2.4 2 0 0 2 2 2 2 Transposase zinc-ribbon domain Nudix_N_2 PF14803.6 EWM21114.1 - 0.0067 16.3 1.0 0.0067 16.3 1.0 2.5 3 0 0 3 3 3 1 Nudix N-terminal YacG PF03884.14 EWM21114.1 - 0.081 12.7 4.3 0.47 10.2 1.9 2.4 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG Lar_restr_allev PF14354.6 EWM21114.1 - 0.17 12.3 4.2 2.5 8.5 0.2 2.3 2 0 0 2 2 2 0 Restriction alleviation protein Lar zf-Di19 PF05605.12 EWM21114.1 - 0.39 11.0 9.8 3.5 8.0 1.7 3.6 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Elf1 PF05129.13 EWM21114.1 - 2.2 8.4 9.3 0.69 10.0 0.3 2.7 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like LPD24 PF18839.1 EWM21115.1 - 0.035 14.4 0.0 0.047 14.0 0.0 1.2 1 0 0 1 1 1 0 Large polyvalent protein associated domain 24 Bot1p PF12298.8 EWM21116.1 - 0.018 15.2 7.9 0.029 14.6 0.1 2.7 2 0 0 2 2 2 0 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.7 EWM21116.1 - 0.059 13.5 0.1 0.22 11.7 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal protein subunit L20 HEAT PF02985.22 EWM21118.1 - 4.3e-05 23.4 11.7 1.3 9.5 0.1 6.9 7 0 0 7 7 7 4 HEAT repeat UAA PF08449.11 EWM21119.1 - 4.7e-51 173.8 19.2 5.5e-51 173.6 19.2 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EWM21119.1 - 0.001 19.2 30.9 0.0018 18.4 17.0 2.7 2 1 0 2 2 2 2 EamA-like transporter family NAD_binding_10 PF13460.6 EWM21120.1 - 3.8e-33 114.9 0.0 6.5e-33 114.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EWM21120.1 - 3.3e-09 36.7 0.2 6e-09 35.8 0.2 1.4 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 EWM21120.1 - 3.1e-05 23.1 0.0 5.5e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EWM21120.1 - 5.6e-05 22.7 0.0 8.8e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EWM21120.1 - 0.049 13.0 0.0 0.094 12.1 0.0 1.5 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RRM_1 PF00076.22 EWM21121.1 - 8.8e-20 70.3 0.0 1.4e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.6 EWM21121.1 - 5.2e-09 36.4 0.1 2.4e-08 34.3 0.0 2.0 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_5 PF13893.6 EWM21121.1 - 7.7e-05 22.3 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EWM21121.1 - 0.024 14.5 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif Clat_adaptor_s PF01217.20 EWM21122.1 - 3e-44 150.4 1.4 3.5e-44 150.2 1.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain BCDHK_Adom3 PF10436.9 EWM21123.1 - 3.8e-42 143.9 0.0 5.3e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EWM21123.1 - 1.4e-12 48.1 0.0 2.6e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EWM21123.1 - 0.00023 21.0 0.0 0.00042 20.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cellulase PF00150.18 EWM21124.1 - 3.8e-30 105.3 0.9 5.1e-30 104.9 0.9 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PAC3 PF10178.9 EWM21125.1 - 2.7e-19 69.1 0.0 5.4e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 POC3_POC4 PF10448.9 EWM21125.1 - 0.069 13.2 0.0 0.17 11.9 0.0 1.6 1 1 0 1 1 1 0 20S proteasome chaperone assembly proteins 3 and 4 EF1G PF00647.19 EWM21126.1 - 3.6e-38 129.9 0.2 6.4e-38 129.1 0.2 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 EWM21126.1 - 1e-16 61.0 0.0 3.9e-16 59.1 0.0 2.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EWM21126.1 - 1.4e-14 54.0 0.0 1.4e-14 54.0 0.0 2.5 2 1 0 2 2 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EWM21126.1 - 1.9e-10 41.0 0.0 4.8e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EWM21126.1 - 8.3e-08 32.1 0.0 2.3e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EWM21126.1 - 2.1e-05 24.7 2.1 2.7e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EWM21126.1 - 0.00011 22.4 0.0 0.00061 20.0 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_5 PF18485.1 EWM21126.1 - 0.00018 21.8 0.0 0.00045 20.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 EWM21126.1 - 0.012 15.4 0.0 0.03 14.1 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 EWM21126.1 - 0.024 14.9 1.9 0.28 11.5 0.0 3.1 3 1 0 3 3 2 0 Outer mitochondrial membrane transport complex protein DUF3692 PF12469.8 EWM21126.1 - 0.19 12.0 0.7 2.4 8.4 0.7 2.5 1 1 0 1 1 1 0 CRISPR-associated protein Noc2 PF03715.13 EWM21127.1 - 3.9e-80 269.3 0.0 6.2e-80 268.6 0.0 1.3 1 0 0 1 1 1 1 Noc2p family RRM_1 PF00076.22 EWM21128.1 - 3.6e-39 132.4 0.0 3.9e-18 65.0 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EWM21128.1 - 3.6e-10 39.6 0.0 0.00014 21.7 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 EWM21128.1 - 2e-05 24.2 0.0 0.00024 20.7 0.0 2.2 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EWM21128.1 - 0.0011 19.0 0.0 0.0023 18.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif Limkain-b1 PF11608.8 EWM21128.1 - 0.0059 16.7 0.1 1.9 8.6 0.0 3.2 2 1 1 3 3 3 1 Limkain b1 DUF4154 PF13689.6 EWM21128.1 - 0.0069 16.6 0.0 18 5.5 0.0 3.0 3 0 0 3 3 3 2 YfiR/HmsC-like DbpA PF03880.15 EWM21128.1 - 0.018 15.0 0.3 9.2 6.3 0.0 3.4 4 0 0 4 4 4 0 DbpA RNA binding domain XS PF03468.14 EWM21128.1 - 0.039 14.3 0.0 0.24 11.7 0.0 2.0 2 0 0 2 2 2 0 XS domain tRNA-synt_1b PF00579.25 EWM21129.1 - 6.3e-08 32.3 0.0 1.9e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) GH43_C PF16369.5 EWM21130.1 - 0.029 15.0 0.0 0.057 14.1 0.0 1.4 1 0 0 1 1 1 0 C-terminal lipocalin-like domain DUF2059 PF09832.9 EWM21131.1 - 2.2e-07 30.8 0.9 6.7e-07 29.3 0.9 1.9 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2059) V_ATPase_I PF01496.19 EWM21131.1 - 0.02 12.9 0.6 0.031 12.2 0.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4834 PF16118.5 EWM21131.1 - 0.033 15.2 3.0 0.039 14.9 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) CRA PF06589.11 EWM21131.1 - 0.044 13.9 0.1 0.1 12.7 0.1 1.6 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) CSG2 PF16965.5 EWM21131.1 - 0.26 10.2 0.1 0.37 9.7 0.1 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator O-antigen_lig PF13425.6 EWM21131.1 - 0.36 9.6 0.3 0.36 9.6 0.3 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Phage_GP20 PF06810.11 EWM21132.1 - 0.0061 16.4 8.0 0.0061 16.4 8.0 3.8 3 1 1 4 4 4 1 Phage minor structural protein GP20 RACo_C_ter PF14574.6 EWM21132.1 - 0.14 11.1 0.2 0.28 10.2 0.2 1.4 1 0 0 1 1 1 0 C-terminal domain of RACo the ASKHA domain Hemagglutinin PF00509.18 EWM21132.1 - 0.22 9.9 2.1 0.37 9.2 2.1 1.2 1 0 0 1 1 1 0 Haemagglutinin Nbl1_Borealin_N PF10444.9 EWM21132.1 - 0.46 10.2 6.6 0.33 10.6 1.5 3.1 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal BLOC1_2 PF10046.9 EWM21132.1 - 1.1 9.6 18.7 1.3 9.4 0.4 4.6 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATG16 PF08614.11 EWM21132.1 - 1.9 8.7 51.3 1.1 9.4 16.4 4.5 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 EWM21132.1 - 2.1 8.4 52.2 1.9 8.6 2.7 6.0 3 3 3 6 6 6 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 EWM21132.1 - 4.9 7.2 21.4 0.93 9.5 1.2 4.1 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 EWM21132.1 - 6.5 6.9 20.8 7.5 6.7 0.6 3.9 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF948 PF06103.11 EWM21132.1 - 6.6 7.1 10.1 1.4 9.2 0.2 3.9 3 2 0 3 3 3 0 Bacterial protein of unknown function (DUF948) VDE PF07137.11 EWM21133.1 - 2.6e-93 311.9 3.1 3.7e-93 311.4 3.1 1.2 1 0 0 1 1 1 1 VDE lipocalin domain SWI-SNF_Ssr4 PF08549.10 EWM21133.1 - 0.33 9.5 1.7 0.43 9.2 1.7 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) INCENP_ARK-bind PF03941.15 EWM21134.1 - 8.3e-13 48.1 0.3 1.9e-12 46.9 0.3 1.7 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region ADH_zinc_N PF00107.26 EWM21135.1 - 8.5e-21 74.3 0.0 1.5e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EWM21135.1 - 4.2e-18 65.2 1.5 8.6e-18 64.2 1.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 EWM21135.1 - 0.018 14.3 0.7 0.03 13.6 0.7 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 EWM21135.1 - 0.15 12.3 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Met_10 PF02475.16 EWM21135.1 - 0.16 11.7 0.1 0.27 10.9 0.1 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Rubis-subs-bind PF09273.11 EWM21136.1 - 1.1e-05 26.1 0.0 2.5e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 EWM21136.1 - 1.7e-05 25.3 0.0 0.00011 22.6 0.0 2.3 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 EWM21137.1 - 1.1e-05 26.1 0.0 2.7e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 EWM21137.1 - 1.8e-05 25.2 0.0 0.00012 22.5 0.0 2.3 1 1 0 1 1 1 1 SET domain Aminotran_1_2 PF00155.21 EWM21138.1 - 7e-73 245.9 0.0 8.2e-73 245.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF1688 PF07958.11 EWM21139.1 - 1.8e-158 527.7 0.0 2e-158 527.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) IF4E PF01652.18 EWM21140.1 - 5.1e-38 130.4 0.0 6.3e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E IF4E PF01652.18 EWM21141.1 - 4.1e-38 130.7 0.0 4.9e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Myb_DNA-binding PF00249.31 EWM21142.1 - 8.8e-29 99.4 7.3 1.3e-15 57.3 1.3 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EWM21142.1 - 2.9e-20 72.3 4.7 3.3e-14 52.9 1.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EWM21142.1 - 0.0011 18.9 0.1 0.08 13.0 0.0 2.4 1 1 1 2 2 2 1 SLIDE Myb_DNA-bind_7 PF15963.5 EWM21142.1 - 0.014 15.3 0.1 0.04 13.8 0.1 1.7 1 0 0 1 1 1 0 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 EWM21142.1 - 0.12 12.8 4.2 0.21 12.0 0.2 2.5 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Ecm29 PF13001.7 EWM21143.1 - 1.1e-20 73.8 0.0 1.3e-20 73.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome stabiliser Sdh_cyt PF01127.22 EWM21144.1 - 1.5e-16 60.5 0.5 2.1e-16 60.1 0.5 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Sdh_cyt PF01127.22 EWM21145.1 - 1.1e-12 48.1 1.3 1.5e-12 47.6 1.3 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Pkinase PF00069.25 EWM21146.1 - 3.5e-55 187.2 0.0 4.2e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM21146.1 - 6.2e-30 104.3 0.0 7.7e-30 104.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EWM21146.1 - 7.3e-07 28.8 0.1 0.00059 19.2 0.0 2.5 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 EWM21146.1 - 4.5e-06 26.2 0.7 9.2e-06 25.1 0.7 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EWM21146.1 - 0.00015 20.7 0.0 0.00021 20.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EWM21146.1 - 0.014 15.1 0.2 1.3 8.6 0.0 2.9 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EWM21146.1 - 0.15 11.6 0.2 0.22 11.1 0.2 1.2 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EWM21146.1 - 0.28 11.1 2.8 2.6 7.9 2.8 2.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family F-box PF00646.33 EWM21147.1 - 0.0064 16.3 0.8 0.022 14.6 0.8 1.9 1 1 0 1 1 1 1 F-box domain PCI PF01399.27 EWM21148.1 - 3e-15 56.6 0.2 1.1e-14 54.7 0.0 2.2 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 EWM21148.1 - 2.6e-13 49.8 1.1 7.4e-13 48.4 1.1 1.9 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain preATP-grasp_3 PF18301.1 EWM21148.1 - 0.075 13.3 0.1 0.24 11.7 0.1 1.9 1 0 0 1 1 1 0 pre ATP-grasp 3 domain KH_1 PF00013.29 EWM21149.1 - 0.033 14.0 0.0 0.077 12.8 0.0 1.7 1 0 0 1 1 1 0 KH domain Macoilin PF09726.9 EWM21149.1 - 2.2 6.7 13.1 4.2 5.8 13.1 1.4 1 0 0 1 1 1 0 Macoilin family TIM21 PF08294.11 EWM21150.1 - 0.23 11.3 0.1 0.23 11.3 0.1 1.6 1 1 1 2 2 2 0 TIM21 DUF4736 PF15883.5 EWM21150.1 - 0.68 9.6 3.5 1.1 9.0 3.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4736) Erythro-docking PF09277.11 EWM21150.1 - 1.7 8.6 0.0 1.7 8.6 0.0 2.7 3 0 0 3 3 3 0 Erythronolide synthase, docking Herpes_UL36 PF03586.13 EWM21151.1 - 0.017 14.5 1.8 0.022 14.1 1.8 1.2 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein DUF5401 PF17380.2 EWM21151.1 - 0.037 12.1 6.8 0.038 12.1 6.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) TMEM247 PF15444.6 EWM21151.1 - 0.12 12.4 2.1 0.14 12.2 2.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 Abi_2 PF07751.11 EWM21151.1 - 0.15 12.3 1.3 0.18 12.1 1.3 1.1 1 0 0 1 1 1 0 Abi-like protein CAP_N PF01213.19 EWM21152.1 - 4.5 6.7 15.3 4.1 6.8 15.3 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 EWM21152.1 - 5.9 6.9 10.2 5.9 6.9 10.2 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Ribosomal_L7Ae PF01248.26 EWM21153.1 - 6.7e-23 80.2 0.4 9.6e-23 79.7 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family X8 PF07983.13 EWM21153.1 - 0.2 12.4 0.0 0.3 11.8 0.0 1.3 1 0 0 1 1 1 0 X8 domain Ribonuc_red_lgC PF02867.15 EWM21155.1 - 7.2e-186 618.8 0.0 1.1e-185 618.2 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EWM21155.1 - 7.8e-21 73.9 0.0 1.9e-20 72.6 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EWM21155.1 - 5e-17 62.2 0.0 9.8e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 ATP cone domain SKI PF01202.22 EWM21156.1 - 1.8e-36 125.7 0.0 2.5e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 EWM21156.1 - 6.8e-05 23.4 0.0 0.00036 21.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EWM21156.1 - 0.00029 21.0 0.1 0.00064 19.9 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EWM21156.1 - 0.0024 18.3 0.0 0.0048 17.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EWM21156.1 - 0.012 16.0 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 EWM21156.1 - 0.024 14.9 0.0 0.051 13.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 EWM21156.1 - 0.027 14.4 0.0 0.073 13.0 0.1 1.7 1 1 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_22 PF13401.6 EWM21156.1 - 0.028 14.7 0.0 0.094 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EWM21156.1 - 0.031 14.7 0.0 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EWM21156.1 - 0.036 13.3 0.3 0.082 12.1 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain ABC_tran PF00005.27 EWM21156.1 - 0.077 13.5 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter CPT PF07931.12 EWM21156.1 - 0.082 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Cytidylate_kin2 PF13189.6 EWM21156.1 - 0.087 13.0 0.1 0.23 11.6 0.0 1.7 2 0 0 2 2 2 0 Cytidylate kinase-like family TsaE PF02367.17 EWM21156.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 EWM21156.1 - 0.14 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_32 PF13654.6 EWM21156.1 - 0.26 10.0 0.4 0.44 9.3 0.1 1.4 2 0 0 2 2 2 0 AAA domain PTPS PF01242.19 EWM21157.1 - 4.5e-19 68.6 0.0 6.4e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase Alkyl_sulf_dimr PF14863.6 EWM21158.1 - 6.2e-29 101.2 0.0 9.6e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.27 EWM21158.1 - 1.2e-05 25.5 0.3 5.2e-05 23.3 0.1 2.1 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Alkyl_sulf_C PF14864.6 EWM21158.1 - 0.04 14.2 0.0 0.076 13.3 0.0 1.4 1 0 0 1 1 1 0 Alkyl sulfatase C-terminal Ank_4 PF13637.6 EWM21159.1 - 6.4e-28 96.8 7.5 6.5e-12 45.7 0.4 4.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EWM21159.1 - 3.9e-25 88.2 0.1 1.7e-11 44.6 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EWM21159.1 - 3.5e-20 70.0 0.6 0.00012 22.2 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EWM21159.1 - 6.8e-18 64.5 1.5 0.00021 21.5 0.1 4.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EWM21159.1 - 1.2e-17 63.5 1.1 0.00018 21.8 0.2 4.7 4 0 0 4 4 4 3 Ankyrin repeat Fer4 PF00037.27 EWM21160.1 - 4.2e-14 51.7 17.0 1.5e-08 34.1 4.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EWM21160.1 - 4.1e-13 49.7 10.4 6.3e-13 49.1 10.4 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EWM21160.1 - 9.4e-10 39.3 7.9 0.00021 22.1 0.2 2.3 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 EWM21160.1 - 1.2e-09 38.2 20.7 2.8e-07 30.6 11.8 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 EWM21160.1 - 3.6e-09 36.6 32.0 3.5e-06 27.0 12.1 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_9 PF13187.6 EWM21160.1 - 7.6e-09 35.6 10.7 1.2e-08 35.0 10.7 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 EWM21160.1 - 4.7e-07 29.6 17.4 0.00038 20.4 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 EWM21160.1 - 6.4e-07 29.7 19.3 2.3e-05 24.8 10.3 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 EWM21160.1 - 1.1e-05 25.6 11.0 0.00027 21.2 1.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 EWM21160.1 - 1.4e-05 24.9 11.9 0.011 15.8 2.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 EWM21160.1 - 0.00079 19.9 11.5 0.018 15.5 11.9 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 EWM21160.1 - 0.0091 16.2 5.3 0.93 9.8 0.4 2.2 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_13 PF13370.6 EWM21160.1 - 0.012 16.1 13.6 0.38 11.3 3.6 2.4 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 EWM21160.1 - 0.013 15.7 7.8 0.65 10.2 1.4 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 EWM21160.1 - 0.044 14.7 16.1 0.076 14.0 3.8 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain ETF_QO PF05187.13 EWM21160.1 - 0.15 12.3 5.9 0.42 10.8 0.7 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 EWM21160.1 - 0.56 11.1 11.8 1.8 9.5 1.7 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain UQ_con PF00179.26 EWM21161.1 - 1.1e-20 73.7 0.0 1.5e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme WRC PF08879.10 EWM21162.1 - 0.039 13.6 1.2 0.074 12.8 0.0 1.9 2 0 0 2 2 2 0 WRC dCMP_cyt_deam_1 PF00383.23 EWM21163.1 - 4.6e-19 68.2 0.0 6.7e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EWM21163.1 - 1.4e-17 63.7 0.0 1.8e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 EWM21163.1 - 2.9e-05 24.1 0.2 0.00024 21.2 0.0 2.0 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 EWM21163.1 - 0.0016 18.5 0.8 0.01 15.9 0.8 2.0 1 1 0 1 1 1 1 APOBEC2 NAD1 PF18778.1 EWM21163.1 - 0.0082 16.2 0.2 0.026 14.6 0.0 1.7 2 0 0 2 2 2 1 Novel AID APOBEC clade 1 APOBEC4_like PF18774.1 EWM21163.1 - 0.018 15.0 0.0 0.058 13.3 0.0 1.8 1 1 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase NAD2 PF18782.1 EWM21163.1 - 0.024 14.8 0.0 0.076 13.1 0.0 1.7 2 0 0 2 2 2 0 Novel AID APOBEC clade 2 LUD_dom PF02589.15 EWM21163.1 - 0.14 11.8 0.1 0.26 11.0 0.1 1.4 1 0 0 1 1 1 0 LUD domain APOBEC_N PF08210.11 EWM21163.1 - 0.17 11.8 1.6 0.33 10.8 1.6 1.6 1 1 0 1 1 1 0 APOBEC-like N-terminal domain Bd3614-deam PF14439.6 EWM21163.1 - 0.19 11.8 1.0 0.49 10.5 0.8 1.7 1 1 1 2 2 2 0 Bd3614-like deaminase EPL1 PF10513.9 EWM21164.1 - 0.00021 21.7 0.0 0.00031 21.1 0.0 1.3 1 0 0 1 1 1 1 Enhancer of polycomb-like HNF_C PF09354.10 EWM21165.1 - 0.63 11.1 4.6 0.91 10.6 1.0 2.7 2 0 0 2 2 2 0 HNF3 C-terminal domain LSM PF01423.22 EWM21166.1 - 8.7e-15 54.2 0.4 1.4e-14 53.5 0.4 1.2 1 0 0 1 1 1 1 LSM domain DEAD PF00270.29 EWM21167.1 - 1.5e-49 168.1 0.0 3.4e-49 167.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase GUCT PF08152.12 EWM21167.1 - 5.1e-26 90.8 0.0 1.2e-25 89.7 0.0 1.7 1 0 0 1 1 1 1 GUCT (NUC152) domain Helicase_C PF00271.31 EWM21167.1 - 4.8e-25 88.1 0.0 1.2e-23 83.5 0.0 2.9 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 EWM21167.1 - 1.5e-08 34.9 0.0 2e-07 31.1 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EWM21167.1 - 0.012 15.4 0.0 0.036 13.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.6 EWM21167.1 - 0.014 14.7 0.0 0.014 14.7 0.0 2.6 2 1 1 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit RR_TM4-6 PF06459.12 EWM21167.1 - 5.8 6.7 12.9 9.3 6.0 12.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 WW PF00397.26 EWM21168.1 - 5.1e-23 80.8 6.8 5.5e-12 45.6 0.1 2.7 2 0 0 2 2 2 2 WW domain FYVE PF01363.21 EWM21168.1 - 2e-14 53.5 9.9 3.5e-14 52.7 9.9 1.4 1 0 0 1 1 1 1 FYVE zinc finger Arm PF00514.23 EWM21168.1 - 2.1e-06 27.6 21.7 3.7 7.7 0.0 8.5 9 0 0 9 9 9 5 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 EWM21168.1 - 0.031 14.5 0.3 7 6.9 0.0 3.6 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 EWM21168.1 - 0.29 11.5 16.2 3.7 8.1 0.0 6.2 7 0 0 7 7 7 0 HEAT repeat FYVE_2 PF02318.16 EWM21168.1 - 0.8 9.9 12.1 2.4 8.4 11.5 2.0 1 1 1 2 2 2 0 FYVE-type zinc finger Ribosomal_S2 PF00318.20 EWM21169.1 - 1.4e-24 86.5 0.0 1.5e-12 47.2 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 EWM21169.1 - 0.00045 21.5 2.9 0.00093 20.5 2.9 1.6 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus CPSF_A PF03178.15 EWM21170.1 - 2.7e-53 181.4 0.0 3.2e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 CPSF A subunit region Kinesin PF00225.23 EWM21171.1 - 8.8e-86 287.8 0.0 3.4e-85 285.9 0.0 2.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EWM21171.1 - 7.2e-39 133.1 0.0 6.3e-38 130.0 0.0 2.6 1 1 0 1 1 1 1 Microtubule binding HMMR_N PF15905.5 EWM21171.1 - 7.3e-05 22.4 37.8 7.3e-05 22.4 37.8 10.3 6 2 4 10 10 10 1 Hyaluronan mediated motility receptor N-terminal UPF0242 PF06785.11 EWM21171.1 - 0.0024 18.0 4.6 0.0024 18.0 4.6 11.0 6 3 6 12 12 12 3 Uncharacterised protein family (UPF0242) N-terminus DUF4710 PF15828.5 EWM21171.1 - 5.1 7.3 9.1 0.34 11.0 1.4 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) Polysacc_synt PF01943.17 EWM21172.1 - 0.022 14.2 1.1 0.031 13.6 1.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF3458_C PF17432.2 EWM21173.1 - 6.6e-116 387.2 0.7 1.2e-115 386.3 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats Peptidase_M1 PF01433.20 EWM21173.1 - 2.1e-52 177.8 0.4 3e-52 177.3 0.4 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain DUF3458 PF11940.8 EWM21173.1 - 1.8e-31 108.4 0.0 3.7e-31 107.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold Peptidase_M1_N PF17900.1 EWM21173.1 - 1.8e-13 51.1 0.0 3.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 EWM21173.1 - 0.00046 20.6 0.3 0.0058 17.0 0.3 2.5 1 1 0 1 1 1 1 M61 glycyl aminopeptidase DUF2268 PF10026.9 EWM21173.1 - 0.11 12.1 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) PAP_fibrillin PF04755.12 EWM21174.1 - 9e-31 107.4 0.3 8.8e-16 58.4 0.1 2.3 2 0 0 2 2 2 2 PAP_fibrillin DUF2310 PF10071.9 EWM21174.1 - 0.2 10.9 0.0 0.26 10.5 0.0 1.1 1 0 0 1 1 1 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) Kinesin PF00225.23 EWM21175.1 - 3.2e-88 295.8 0.0 5.3e-88 295.1 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EWM21175.1 - 5e-23 81.7 0.0 1.6e-19 70.3 0.0 2.5 2 0 0 2 2 2 2 Microtubule binding Med4 PF10018.9 EWM21175.1 - 0.0046 16.7 0.9 0.0046 16.7 0.9 2.2 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF3584 PF12128.8 EWM21175.1 - 0.12 9.9 23.8 0.17 9.4 23.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Exonuc_VII_L PF02601.15 EWM21175.1 - 0.21 11.1 7.7 0.37 10.3 7.7 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit ERM PF00769.19 EWM21175.1 - 0.44 10.3 24.5 0.84 9.4 24.5 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family AAA_23 PF13476.6 EWM21175.1 - 0.59 10.6 13.7 0.11 12.9 4.5 3.2 3 0 0 3 3 3 0 AAA domain Macoilin PF09726.9 EWM21175.1 - 0.88 8.1 10.0 1.3 7.5 10.0 1.2 1 0 0 1 1 1 0 Macoilin family FPP PF05911.11 EWM21175.1 - 1.5 6.9 17.3 1.4 7.0 15.6 1.5 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil GIT_CC PF16559.5 EWM21175.1 - 3.2 7.7 4.7 18 5.3 1.4 2.9 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor FmiP_Thoc5 PF09766.9 EWM21175.1 - 4.2 6.6 18.5 0.15 11.3 9.3 2.1 1 1 1 2 2 2 0 Fms-interacting protein/Thoc5 HAUS-augmin3 PF14932.6 EWM21175.1 - 6.5 6.2 17.4 12 5.4 17.0 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 EzrA PF06160.12 EWM21175.1 - 8.5 4.4 15.7 0.19 9.9 7.2 1.9 1 1 0 2 2 2 0 Septation ring formation regulator, EzrA MFS_1_like PF12832.7 EWM21176.1 - 7.4e-75 252.2 4.5 1e-74 251.8 4.5 1.2 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 EWM21176.1 - 5.3e-29 101.2 48.5 1.4e-24 86.7 23.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 EWM21176.1 - 1.2e-11 44.2 7.6 8.6e-07 28.3 1.2 2.1 2 0 0 2 2 2 2 Nucleoside H+ symporter LacY_symp PF01306.19 EWM21176.1 - 9.5e-05 21.3 1.9 9.5e-05 21.3 1.9 2.0 2 0 0 2 2 2 1 LacY proton/sugar symporter MFS_2 PF13347.6 EWM21176.1 - 0.00049 18.8 9.6 0.061 11.9 2.1 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein DUF1056 PF06341.11 EWM21176.1 - 0.61 10.4 4.5 0.23 11.8 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1056) E1-E2_ATPase PF00122.20 EWM21177.1 - 2e-45 154.5 1.8 2e-45 154.5 1.8 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EWM21177.1 - 1.9e-17 64.3 0.2 2.3e-16 60.7 0.2 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EWM21177.1 - 9.1e-12 44.5 0.1 8.3e-11 41.4 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EWM21177.1 - 0.00015 21.6 0.6 0.00076 19.3 0.1 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Met_10 PF02475.16 EWM21178.1 - 6.1e-46 156.7 0.1 2.4e-28 99.2 0.0 2.1 1 1 1 2 2 2 2 Met-10+ like-protein PPR_3 PF13812.6 EWM21178.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Pentatricopeptide repeat domain MethyltransfD12 PF02086.15 EWM21178.1 - 0.29 10.8 0.0 0.47 10.1 0.0 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Sulfatase PF00884.23 EWM21179.1 - 2.6e-59 201.1 0.0 3.7e-59 200.6 0.0 1.2 1 0 0 1 1 1 1 Sulfatase DUF1501 PF07394.12 EWM21179.1 - 0.00076 18.6 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) Phosphodiest PF01663.22 EWM21179.1 - 0.0034 17.0 0.1 0.79 9.2 0.0 2.4 2 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EWM21180.1 - 1.7e-59 201.8 0.0 2.2e-59 201.4 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF1501 PF07394.12 EWM21180.1 - 0.00058 19.0 0.0 0.001 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) Phosphodiest PF01663.22 EWM21180.1 - 0.002 17.8 0.1 0.66 9.5 0.0 2.4 2 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Choline_transpo PF04515.12 EWM21181.1 - 1.5e-66 224.8 31.2 4.1e-66 223.4 25.4 2.1 2 0 0 2 2 2 2 Plasma-membrane choline transporter LRR_6 PF13516.6 EWM21182.1 - 0.0006 19.7 0.5 0.092 12.8 0.2 3.0 2 0 0 2 2 2 2 Leucine Rich repeat Meckelin PF09773.9 EWM21182.1 - 0.0087 14.2 0.1 0.0087 14.2 0.1 1.4 2 0 0 2 2 2 1 Meckelin (Transmembrane protein 67) HA2 PF04408.23 EWM21188.1 - 6.2e-12 45.7 0.0 1.4e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EWM21188.1 - 3.5e-08 33.8 0.0 6.2e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain BOP1NT PF08145.12 EWM21190.1 - 9.3e-39 133.9 0.0 1.3e-38 133.4 0.0 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain DUF2457 PF10446.9 EWM21190.1 - 5.9 5.9 13.6 7.1 5.7 13.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) WD40 PF00400.32 EWM21191.1 - 1.3e-22 79.7 3.1 1.2e-05 26.0 0.0 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM21191.1 - 9.3e-06 25.9 0.0 1.4 9.3 0.0 3.8 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_1 PF00515.28 EWM21192.1 - 1.1e-10 40.8 5.9 2.6e-05 23.9 0.3 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EWM21192.1 - 3.3e-08 33.0 8.3 0.00011 22.1 0.4 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EWM21192.1 - 1.3e-05 25.6 1.2 4e-05 24.0 1.2 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 EWM21192.1 - 6.6e-05 23.5 1.0 6.6e-05 23.5 1.0 2.6 3 0 0 3 3 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EWM21192.1 - 0.0001 22.5 3.8 0.0001 22.5 3.8 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EWM21192.1 - 0.00022 21.4 2.1 0.0053 17.1 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EWM21192.1 - 0.00055 19.9 4.3 0.02 15.1 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 EWM21192.1 - 0.0031 17.8 1.1 0.0074 16.6 1.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 EWM21192.1 - 0.038 14.8 0.3 0.038 14.8 0.3 3.8 2 1 2 4 4 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EWM21192.1 - 0.068 12.9 0.1 1.5 8.5 0.0 2.6 1 1 1 2 2 2 0 TPR repeat Fis1_TPR_C PF14853.6 EWM21192.1 - 0.073 13.2 1.3 12 6.0 0.2 2.7 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 EWM21192.1 - 0.075 13.1 0.2 0.26 11.4 0.2 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_4 PF07721.14 EWM21192.1 - 0.22 12.3 0.1 0.22 12.3 0.1 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EWM21192.1 - 0.85 9.9 11.8 0.11 12.9 1.0 3.2 2 1 1 3 3 2 0 Tetratricopeptide repeat BTAD PF03704.17 EWM21192.1 - 1.1 9.7 10.5 0.43 11.0 6.8 2.1 1 1 1 2 2 2 0 Bacterial transcriptional activator domain DnaJ PF00226.31 EWM21194.1 - 1.8e-20 72.8 0.4 4e-20 71.7 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain DUF4523 PF15023.6 EWM21194.1 - 2.6e-06 27.4 0.0 4.7e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4523) RRM_1 PF00076.22 EWM21194.1 - 4.2e-05 23.3 0.0 0.0003 20.6 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M16 PF00675.20 EWM21194.1 - 0.28 11.1 1.9 0.44 10.5 0.2 2.0 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) Smr PF01713.21 EWM21198.1 - 0.00019 21.8 0.2 0.00037 20.8 0.2 1.5 1 0 0 1 1 1 1 Smr domain PPR_1 PF12854.7 EWM21198.1 - 0.00035 20.2 0.1 0.0071 16.0 0.0 2.4 2 0 0 2 2 2 1 PPR repeat PPR PF01535.20 EWM21198.1 - 0.00065 19.8 0.2 0.012 15.8 0.0 2.6 2 0 0 2 2 2 1 PPR repeat Cupin_6 PF12852.7 EWM21198.1 - 0.06 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Cupin PPR_3 PF13812.6 EWM21198.1 - 0.066 13.3 0.0 0.97 9.6 0.0 2.3 2 0 0 2 2 2 0 Pentatricopeptide repeat domain HECT PF00632.25 EWM21199.1 - 1.1e-12 48.1 0.0 1.2e-12 47.9 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) PHD PF00628.29 EWM21200.1 - 2.1e-05 24.3 1.0 4.2e-05 23.3 1.0 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EWM21200.1 - 0.075 12.6 5.4 0.14 11.7 5.4 1.4 1 0 0 1 1 1 0 PHD-finger DARPP-32 PF05395.12 EWM21200.1 - 0.39 10.9 6.1 0.61 10.3 6.1 1.4 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 TFIIA PF03153.13 EWM21200.1 - 0.65 9.9 3.5 0.85 9.6 3.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 EWM21200.1 - 1.5 6.9 14.1 2 6.5 14.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EWM21200.1 - 8.1 4.6 6.7 10 4.2 6.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DAO PF01266.24 EWM21201.1 - 4.5e-05 23.2 0.2 6.5e-05 22.7 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EWM21201.1 - 0.00016 21.8 0.1 0.00042 20.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EWM21201.1 - 0.00025 20.2 1.0 0.0064 15.6 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 EWM21201.1 - 0.00055 19.2 0.0 0.00089 18.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EWM21201.1 - 0.0015 17.8 0.1 0.0048 16.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EWM21201.1 - 0.0057 15.8 0.3 0.007 15.5 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 EWM21201.1 - 0.011 15.0 1.6 0.74 9.0 0.2 2.1 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 EWM21201.1 - 0.06 12.2 0.0 0.069 12.0 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase FAD_oxidored PF12831.7 EWM21201.1 - 0.071 12.4 0.1 0.078 12.3 0.1 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EWM21201.1 - 0.072 13.1 0.4 0.32 11.0 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Mqo PF06039.15 EWM21201.1 - 0.084 11.4 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) 60KD_IMP PF02096.20 EWM21207.1 - 0.00073 19.5 0.0 0.0008 19.4 0.0 1.0 1 0 0 1 1 1 1 60Kd inner membrane protein Sporozoite_P67 PF05642.11 EWM21208.1 - 0.6 8.1 7.4 0.67 8.0 7.4 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Macoilin PF09726.9 EWM21208.1 - 1.2 7.7 6.4 1.4 7.4 6.4 1.0 1 0 0 1 1 1 0 Macoilin family PAP1 PF08601.10 EWM21208.1 - 2.7 7.6 12.9 3.2 7.4 12.9 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 zf-GRF PF06839.12 EWM21209.1 - 3.1e-08 33.6 7.1 5.1e-08 32.9 7.1 1.4 1 0 0 1 1 1 1 GRF zinc finger Zn_Tnp_IS1595 PF12760.7 EWM21209.1 - 0.088 12.8 2.1 0.21 11.6 2.1 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain NUDIX PF00293.28 EWM21211.1 - 1.3e-12 47.9 0.1 2e-12 47.3 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain MaoC_dehydrat_N PF13452.6 EWM21211.1 - 0.015 15.4 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 N-terminal half of MaoC dehydratase Peptidase_A22B PF04258.13 EWM21213.1 - 9.5e-15 54.9 0.0 6e-14 52.2 0.0 1.9 1 1 0 1 1 1 1 Signal peptide peptidase YjbE PF11106.8 EWM21213.1 - 5.3 7.3 11.4 14 5.9 11.4 1.7 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE Peptidase_A22B PF04258.13 EWM21214.1 - 9.5e-15 54.9 0.0 6e-14 52.2 0.0 1.9 1 1 0 1 1 1 1 Signal peptide peptidase YjbE PF11106.8 EWM21214.1 - 5.3 7.3 11.4 14 5.9 11.4 1.7 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE PseudoU_synth_2 PF00849.22 EWM21217.1 - 1.9e-05 24.8 0.4 2.9e-05 24.2 0.4 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase PT PF04886.12 EWM21220.1 - 0.00012 21.6 9.1 0.00012 21.6 9.1 1.8 2 0 0 2 2 2 1 PT repeat S4 PF01479.25 EWM21221.1 - 2.2e-09 36.9 0.2 4.1e-09 36.0 0.2 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 EWM21221.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 S4 domain PAP_fibrillin PF04755.12 EWM21222.1 - 7e-08 32.6 0.1 0.0023 17.9 0.2 2.7 2 1 0 2 2 2 2 PAP_fibrillin TFIIF_alpha PF05793.12 EWM21224.1 - 0.76 8.3 51.8 1.2 7.7 51.8 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Trigger_N PF05697.13 EWM21225.1 - 5e-06 26.9 0.0 8.7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial trigger factor protein (TF) Methyltransf_16 PF10294.9 EWM21226.1 - 0.14 11.9 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase PX PF00787.24 EWM21227.1 - 1.2e-08 34.9 0.0 1.8e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 PX domain V_ATPase_I PF01496.19 EWM21229.1 - 4.2 5.2 11.3 0.51 8.2 7.4 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Beta-lactamase PF00144.24 EWM21231.1 - 1.5e-48 165.7 0.0 2.1e-48 165.3 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase BT1 PF03092.16 EWM21233.1 - 2.1e-10 39.5 1.2 2.6e-10 39.2 1.2 1.1 1 0 0 1 1 1 1 BT1 family GMC_oxred_N PF00732.19 EWM21237.1 - 6e-17 61.9 0.1 6.5e-17 61.8 0.1 1.0 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 EWM21237.1 - 7.9e-07 28.6 0.1 7.9e-07 28.6 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EWM21237.1 - 4.6e-05 22.6 0.1 6e-05 22.3 0.1 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EWM21237.1 - 0.00013 21.3 0.0 0.00015 21.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EWM21237.1 - 0.00016 20.9 1.0 0.00023 20.4 1.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EWM21237.1 - 0.00029 21.0 0.3 0.00063 19.9 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EWM21237.1 - 0.00042 20.0 1.2 0.00072 19.2 0.9 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EWM21237.1 - 0.0015 17.8 0.1 0.0021 17.4 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 EWM21237.1 - 0.0039 16.8 0.1 0.0046 16.6 0.1 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 EWM21237.1 - 0.0045 17.2 0.0 0.0058 16.9 0.0 1.2 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox PF00070.27 EWM21237.1 - 0.0048 17.4 0.1 0.0067 17.0 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EWM21237.1 - 0.007 15.1 0.4 0.0088 14.8 0.4 1.1 1 0 0 1 1 1 1 HI0933-like protein Shikimate_DH PF01488.20 EWM21237.1 - 0.0075 16.3 0.0 0.01 15.9 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 EWM21237.1 - 0.019 14.9 0.3 0.034 14.1 0.2 1.5 1 1 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.17 EWM21237.1 - 0.02 14.2 0.1 0.027 13.7 0.1 1.1 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 EWM21237.1 - 0.035 13.2 0.2 0.042 12.9 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF4147 PF13660.6 EWM21237.1 - 0.049 13.2 0.5 0.056 13.0 0.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4147) KOW PF00467.29 EWM21237.1 - 0.15 12.0 2.2 0.33 11.0 2.2 1.5 1 0 0 1 1 1 0 KOW motif ThiF PF00899.21 EWM21237.1 - 0.32 10.3 0.9 0.59 9.4 0.6 1.5 1 1 1 2 2 2 0 ThiF family YL1 PF05764.13 EWM21241.1 - 1.9 8.5 6.8 2.5 8.1 6.8 1.1 1 0 0 1 1 1 0 YL1 nuclear protein DUF1325 PF07039.11 EWM21243.1 - 1.7e-20 73.5 0.1 2.8e-20 72.8 0.1 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain ING PF12998.7 EWM21243.1 - 1.4e-14 54.5 4.0 2e-14 54.0 4.0 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding Fib_alpha PF08702.10 EWM21243.1 - 0.99 9.6 3.2 2.2 8.5 3.1 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Aminotran_1_2 PF00155.21 EWM21247.1 - 0.11 11.6 0.0 0.13 11.4 0.0 1.0 1 0 0 1 1 1 0 Aminotransferase class I and II MutS_V PF00488.21 EWM21249.1 - 3.9e-76 255.3 0.0 5.7e-76 254.7 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_IV PF05190.18 EWM21249.1 - 1.3e-08 35.1 0.1 2.5e-08 34.1 0.1 1.4 1 0 0 1 1 1 1 MutS family domain IV MutS_III PF05192.18 EWM21249.1 - 2.1e-05 24.9 0.0 3.9e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 MutS domain III MnmE_helical PF12631.7 EWM21249.1 - 0.054 13.7 0.0 0.06 13.5 0.0 1.3 1 1 0 1 1 1 0 MnmE helical domain AAA_29 PF13555.6 EWM21249.1 - 0.16 11.8 0.0 0.48 10.2 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EWM21249.1 - 0.21 12.1 0.1 1 9.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain Fe_hyd_SSU PF02256.17 EWM21250.1 - 0.14 12.2 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 Iron hydrogenase small subunit Golgin_A5 PF09787.9 EWM21254.1 - 2.6e-06 27.1 35.3 0.0053 16.3 1.4 3.5 2 1 0 2 2 2 2 Golgin subfamily A member 5 HALZ PF02183.18 EWM21254.1 - 0.0027 17.9 0.3 0.011 15.9 0.1 2.2 1 1 1 2 2 2 1 Homeobox associated leucine zipper Fez1 PF06818.15 EWM21254.1 - 0.0056 17.1 19.4 0.0056 17.1 19.4 2.0 2 0 0 2 2 2 1 Fez1 Lectin_N PF03954.14 EWM21254.1 - 0.4 10.4 9.3 34 4.2 7.2 3.4 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain HMMR_N PF15905.5 EWM21254.1 - 1.9 7.9 20.4 0.98 8.8 14.8 2.1 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF5542 PF17696.1 EWM21254.1 - 2.9 8.1 6.1 9.5 6.4 4.4 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5542) ATG16 PF08614.11 EWM21254.1 - 3.6 7.8 35.3 11 6.2 17.9 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF641 PF04859.12 EWM21254.1 - 7.3 6.9 21.0 4.6 7.6 0.2 3.6 1 1 1 3 3 3 0 Plant protein of unknown function (DUF641) LCD1 PF09798.9 EWM21254.1 - 8.7 4.7 7.3 11 4.4 7.3 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein SBP_bac_3 PF00497.20 EWM21255.1 - 4e-09 36.2 0.0 5.3e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 SBP_bac_3 PF00497.20 EWM21256.1 - 2.5e-05 23.8 0.0 2.6e-05 23.8 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 ZapB PF06005.12 EWM21256.1 - 0.058 13.9 0.0 0.13 12.8 0.0 1.7 1 1 0 1 1 1 0 Cell division protein ZapB Sigma70_ner PF04546.13 EWM21257.1 - 0.0052 16.7 4.8 0.0062 16.4 4.8 1.1 1 0 0 1 1 1 1 Sigma-70, non-essential region Cwf_Cwc_15 PF04889.12 EWM21257.1 - 0.0061 16.3 2.7 0.0061 16.3 2.7 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.11 EWM21257.1 - 0.0074 16.3 0.4 0.011 15.8 0.4 1.4 1 0 0 1 1 1 1 RXT2-like, N-terminal SDA1 PF05285.12 EWM21257.1 - 0.013 15.0 9.1 0.017 14.6 9.1 1.2 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 EWM21257.1 - 0.026 14.1 8.9 0.029 14.0 8.9 1.1 1 0 0 1 1 1 0 PPP4R2 RNA_pol_3_Rpc31 PF11705.8 EWM21257.1 - 0.036 14.3 12.6 0.047 14.0 12.6 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Myc_N PF01056.18 EWM21257.1 - 0.043 13.7 7.6 0.063 13.2 7.6 1.2 1 0 0 1 1 1 0 Myc amino-terminal region TRAP_alpha PF03896.16 EWM21257.1 - 0.048 12.9 2.6 0.069 12.3 2.6 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.12 EWM21257.1 - 0.13 11.5 8.7 0.17 11.1 8.7 1.1 1 0 0 1 1 1 0 NOA36 protein DUF913 PF06025.12 EWM21257.1 - 0.14 11.1 0.8 0.14 11.1 0.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FAM176 PF14851.6 EWM21257.1 - 0.18 11.5 5.3 0.33 10.6 5.3 1.5 1 0 0 1 1 1 0 FAM176 family Pox_Ag35 PF03286.14 EWM21257.1 - 0.32 10.8 6.4 0.17 11.7 4.4 1.5 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF3306 PF11748.8 EWM21257.1 - 0.33 11.8 7.2 0.7 10.8 7.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Paf1 PF03985.13 EWM21257.1 - 0.43 9.5 11.7 0.53 9.2 11.7 1.1 1 0 0 1 1 1 0 Paf1 TFIIA PF03153.13 EWM21257.1 - 0.47 10.4 5.2 0.55 10.2 5.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Prothymosin PF03247.14 EWM21257.1 - 0.67 10.4 26.4 1.1 9.7 26.4 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family Radial_spoke PF04712.12 EWM21257.1 - 0.69 8.8 11.9 0.97 8.3 11.9 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein Nop14 PF04147.12 EWM21257.1 - 0.81 7.8 12.2 1 7.5 12.2 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4637 PF15470.6 EWM21257.1 - 0.99 9.1 11.7 1.6 8.4 11.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) RPN2_C PF18004.1 EWM21257.1 - 1.1 9.2 6.2 1.6 8.7 6.2 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CobT PF06213.12 EWM21257.1 - 1.2 8.5 12.2 1.7 7.9 12.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Fmp27 PF10344.9 EWM21257.1 - 1.3 7.0 2.1 1.7 6.7 2.1 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 CENP-B_dimeris PF09026.10 EWM21257.1 - 1.3 9.4 14.4 2.4 8.6 14.4 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4746 PF15928.5 EWM21257.1 - 1.6 8.1 11.8 2.1 7.7 11.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TMEM119 PF15724.5 EWM21257.1 - 3.1 7.8 14.5 0.1 12.6 6.5 2.0 2 0 0 2 2 2 0 TMEM119 family CDC45 PF02724.14 EWM21257.1 - 6.2 5.0 10.3 8.7 4.5 10.3 1.1 1 0 0 1 1 1 0 CDC45-like protein PWI PF01480.17 EWM21258.1 - 0.064 13.6 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 PWI domain Glyco_hydro_125 PF06824.11 EWM21262.1 - 8.6e-44 150.1 0.0 1.3e-43 149.4 0.0 1.2 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) LRR_6 PF13516.6 EWM21264.1 - 8e-19 66.0 10.8 0.0027 17.6 0.0 7.6 8 0 0 8 8 7 3 Leucine Rich repeat LRR_1 PF00560.33 EWM21264.1 - 4.5e-07 29.5 0.3 3.4 8.6 0.2 5.3 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_4 PF12799.7 EWM21264.1 - 6.7e-06 26.4 4.3 0.023 15.1 0.2 4.3 3 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EWM21264.1 - 0.0021 17.8 6.7 2.8 7.8 1.6 4.6 1 1 2 3 3 3 1 Leucine rich repeat BUD22 PF09073.10 EWM21264.1 - 0.014 14.7 11.7 0.02 14.3 11.7 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 EWM21264.1 - 0.019 14.4 17.5 0.026 14.0 17.5 1.2 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 EWM21264.1 - 0.049 13.4 9.6 0.069 12.9 9.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.8 EWM21264.1 - 0.052 13.8 19.7 0.11 12.8 19.7 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.12 EWM21264.1 - 0.12 10.6 22.1 0.15 10.3 22.1 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 EWM21264.1 - 0.16 10.1 30.3 0.24 9.5 30.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi FAM91_C PF14648.6 EWM21264.1 - 0.26 10.1 0.5 0.31 9.8 0.5 1.1 1 0 0 1 1 1 0 FAM91 C-terminus Paf1 PF03985.13 EWM21264.1 - 0.28 10.2 24.1 0.38 9.7 24.1 1.1 1 0 0 1 1 1 0 Paf1 Presenilin PF01080.17 EWM21264.1 - 0.32 9.7 4.1 0.39 9.4 4.1 1.1 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 EWM21264.1 - 0.44 10.5 8.3 0.53 10.2 8.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CobT PF06213.12 EWM21264.1 - 0.49 9.7 22.1 0.81 9.0 22.1 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Cytochrom_C552 PF02335.15 EWM21264.1 - 0.5 9.2 3.5 0.71 8.7 3.5 1.1 1 0 0 1 1 1 0 Cytochrome c552 RAB3GAP2_C PF14656.6 EWM21264.1 - 0.77 7.9 4.9 1 7.5 4.9 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus RR_TM4-6 PF06459.12 EWM21264.1 - 0.78 9.5 13.0 1.1 9.0 13.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFB6 PF17110.5 EWM21264.1 - 0.83 9.4 8.1 1.7 8.4 8.1 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Mpp10 PF04006.12 EWM21264.1 - 0.97 7.8 22.8 1.2 7.4 22.8 1.1 1 0 0 1 1 1 0 Mpp10 protein Tim54 PF11711.8 EWM21264.1 - 1.5 7.5 11.9 2.4 6.9 11.9 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Sigma70_ner PF04546.13 EWM21264.1 - 1.6 8.5 22.6 2.6 7.9 22.6 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.12 EWM21264.1 - 1.8 7.8 19.1 2.6 7.3 19.1 1.2 1 0 0 1 1 1 0 NOA36 protein EIIBC-GUT_N PF03612.14 EWM21264.1 - 2.2 8.0 5.7 2.4 7.9 4.7 1.6 2 0 0 2 2 1 0 Sorbitol phosphotransferase enzyme II N-terminus RPN2_C PF18004.1 EWM21264.1 - 2.7 7.9 14.1 4 7.3 14.1 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DARPP-32 PF05395.12 EWM21264.1 - 3 8.0 19.8 5.4 7.2 19.8 1.4 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 CDC45 PF02724.14 EWM21264.1 - 3.7 5.7 17.1 5 5.3 17.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 EWM21264.1 - 6 5.7 7.0 8.6 5.2 7.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CENP-T_N PF16171.5 EWM21264.1 - 6.1 5.7 8.8 8.7 5.1 8.8 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T N-terminus Connexin PF00029.19 EWM21264.1 - 6.5 6.4 6.6 9.3 5.9 6.6 1.1 1 0 0 1 1 1 0 Connexin Vfa1 PF08432.10 EWM21264.1 - 6.9 7.0 10.1 10 6.4 10.1 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 MRNIP PF15749.5 EWM21264.1 - 7.4 7.4 8.2 14 6.4 8.2 1.4 1 0 0 1 1 1 0 MRN-interacting protein RNA_pol_Rpc4 PF05132.14 EWM21264.1 - 8.2 6.9 8.2 18 5.7 8.2 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 MRP_L53 PF10780.9 EWM21265.1 - 5.1e-06 26.6 0.0 8.1e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 L51_S25_CI-B8 PF05047.16 EWM21265.1 - 0.00012 21.9 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Glyco_transf_10 PF00852.19 EWM21269.1 - 1.1e-26 93.7 0.0 1.6e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term SNF2_N PF00176.23 EWM21270.1 - 2.5e-30 105.4 0.0 2.9e-30 105.2 0.0 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 EWM21270.1 - 0.018 15.0 0.0 0.023 14.7 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 EWM21270.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 SWI2/SNF2 ATPase DEAD PF00270.29 EWM21270.1 - 0.13 12.0 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase TMEM189_B_dmain PF10520.9 EWM21272.1 - 1.8e-12 47.7 2.0 2.6e-12 47.2 2.0 1.3 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain Choline_kinase PF01633.20 EWM21273.1 - 7.5e-42 143.3 0.0 1.6e-41 142.3 0.0 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EWM21273.1 - 0.00059 19.8 0.0 0.28 11.1 0.0 2.4 2 1 0 2 2 2 2 Phosphotransferase enzyme family IATP PF04568.12 EWM21275.1 - 5.7e-05 23.5 2.7 8.7e-05 22.9 2.7 1.5 1 1 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP TRH PF05438.12 EWM21275.1 - 0.0025 17.6 0.3 0.003 17.3 0.3 1.1 1 0 0 1 1 1 1 Thyrotropin-releasing hormone (TRH) Esterase PF00756.20 EWM21276.1 - 4.3e-48 164.1 0.0 5.5e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Putative esterase EF-hand_7 PF13499.6 EWM21277.1 - 7.2e-26 90.4 7.6 5.6e-13 49.1 2.4 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EWM21277.1 - 1.7e-24 83.4 10.4 6.3e-08 31.6 1.1 4.5 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EWM21277.1 - 1.8e-19 67.9 9.5 1.2e-08 34.1 0.1 4.5 4 1 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 EWM21277.1 - 5.8e-19 67.7 10.9 5.5e-12 45.4 0.4 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 EWM21277.1 - 3.1e-09 37.0 0.3 0.00031 21.0 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EWM21277.1 - 1.1e-07 31.1 19.6 0.0003 20.1 0.2 4.6 4 1 0 4 4 3 3 EF hand Caleosin PF05042.13 EWM21277.1 - 2.5e-05 24.3 0.1 0.21 11.5 0.0 3.1 2 1 1 3 3 3 1 Caleosin related protein EF-hand_14 PF17959.1 EWM21277.1 - 0.00038 20.7 0.5 1.1 9.6 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain SurA_N_2 PF13623.6 EWM21277.1 - 0.0013 18.6 0.6 0.93 9.4 0.1 2.2 2 0 0 2 2 2 2 SurA N-terminal domain HTH_40 PF14493.6 EWM21277.1 - 0.0025 18.2 0.2 0.86 10.1 0.0 2.3 1 1 1 2 2 2 1 Helix-turn-helix domain SPARC_Ca_bdg PF10591.9 EWM21277.1 - 0.0048 17.2 0.3 2 8.8 0.1 2.3 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region SurA_N_3 PF13624.6 EWM21277.1 - 0.013 15.3 1.1 0.95 9.2 0.1 2.2 1 1 0 2 2 2 0 SurA N-terminal domain EF-hand_4 PF12763.7 EWM21277.1 - 0.028 14.3 0.7 0.028 14.3 0.7 2.7 2 1 2 4 4 3 0 Cytoskeletal-regulatory complex EF hand MerR-DNA-bind PF09278.11 EWM21277.1 - 0.029 14.9 0.2 8.2 7.0 0.0 3.3 1 1 2 3 3 3 0 MerR, DNA binding SUB1_ProdP9 PF18213.1 EWM21277.1 - 0.08 12.8 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 SUB1 protease Prodomain ProdP9 Arc_PepC PF06819.11 EWM21277.1 - 0.086 13.0 0.6 1.7 8.8 0.1 2.2 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminal Domain HTH_21 PF13276.6 EWM21277.1 - 0.087 13.0 0.1 2.9 8.1 0.0 2.5 3 0 0 3 3 3 0 HTH-like domain PMBR PF09373.10 EWM21277.1 - 0.14 12.4 0.0 3.1 8.1 0.0 3.0 3 0 0 3 3 3 0 Pseudomurein-binding repeat IF2_N PF04760.15 EWM21277.1 - 0.46 10.3 2.3 4.9 7.0 0.0 3.1 3 1 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region ELO PF01151.18 EWM21280.1 - 2.6e-45 154.9 8.2 3.4e-45 154.5 8.2 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family PP2C PF00481.21 EWM21282.1 - 5.7e-66 222.8 1.2 2.1e-53 181.6 0.5 3.1 2 1 0 2 2 2 2 Protein phosphatase 2C DUF2052 PF09747.9 EWM21282.1 - 0.0048 17.1 6.3 0.0048 17.1 6.3 3.4 2 1 1 3 3 3 1 Coiled-coil domain containing protein (DUF2052) HTH_24 PF13412.6 EWM21282.1 - 0.019 14.5 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HNF-1_N PF04814.13 EWM21282.1 - 1.3 9.6 4.2 3.6 8.2 4.2 1.7 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus PA26 PF04636.13 EWM21282.1 - 3.5 6.4 4.3 6.6 5.5 4.3 1.4 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) PI3K_1B_p101 PF10486.9 EWM21282.1 - 3.9 5.1 5.2 7.4 4.2 5.2 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Rhabdo_ncap PF00945.18 EWM21282.1 - 9.3 5.0 5.5 4.8 5.9 1.9 2.0 2 0 0 2 2 2 0 Rhabdovirus nucleocapsid protein PP2C PF00481.21 EWM21283.1 - 8.5e-66 222.2 1.4 2.5e-53 181.3 0.6 3.1 2 1 0 2 2 2 2 Protein phosphatase 2C DUF2052 PF09747.9 EWM21283.1 - 0.0038 17.4 5.8 0.0038 17.4 5.8 3.4 2 1 1 3 3 3 1 Coiled-coil domain containing protein (DUF2052) HTH_24 PF13412.6 EWM21283.1 - 0.021 14.4 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding PA26 PF04636.13 EWM21283.1 - 4 6.3 4.3 7.5 5.4 4.3 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) PI3K_1B_p101 PF10486.9 EWM21283.1 - 4.4 5.0 5.2 8 4.1 5.2 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Acetyltransf_1 PF00583.25 EWM21284.1 - 0.00015 21.9 0.0 0.15 12.3 0.0 2.7 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EWM21284.1 - 0.00041 20.7 0.0 0.002 18.5 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EWM21284.1 - 0.002 18.2 0.0 0.33 11.0 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 EWM21284.1 - 0.088 12.8 0.1 7.5 6.6 0.0 2.3 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_10 PF13673.7 EWM21284.1 - 0.17 11.8 0.0 4.4 7.2 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Glyoxalase PF00903.25 EWM21285.1 - 0.00013 22.2 0.4 0.00046 20.4 0.4 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 EWM21285.1 - 0.14 12.1 0.1 0.31 11.0 0.0 1.5 2 0 0 2 2 2 0 Glyoxalase-like domain MttA_Hcf106 PF02416.16 EWM21287.1 - 4.4e-08 32.3 0.7 6.7e-08 31.7 0.7 1.4 1 0 0 1 1 1 1 mttA/Hcf106 family FGF-BP1 PF06473.12 EWM21287.1 - 0.069 13.0 0.3 0.1 12.4 0.3 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) DUF4726 PF15855.5 EWM21291.1 - 1.4 9.1 4.2 0.64 10.3 0.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4726) AAA_2 PF07724.14 EWM21292.1 - 1.5e-11 44.7 0.0 1.8e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.9 EWM21294.1 - 1.5e-14 53.7 0.0 2.2e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein UPF1_Zn_bind PF09416.10 EWM21295.1 - 2.7e-72 241.7 1.0 2.7e-72 241.7 1.0 1.9 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_11 PF13086.6 EWM21295.1 - 2.9e-50 171.5 2.8 5.4e-30 105.0 0.3 2.4 1 1 1 2 2 2 2 AAA domain AAA_12 PF13087.6 EWM21295.1 - 1e-25 90.5 0.0 2e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF5599 PF18141.1 EWM21295.1 - 1.2e-24 86.3 0.0 2.8e-24 85.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 EWM21295.1 - 2.6e-15 56.6 2.6 6.7e-14 52.1 0.4 3.0 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EWM21295.1 - 3.2e-12 47.0 0.2 6.9e-12 45.9 0.2 1.6 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 EWM21295.1 - 1.5e-06 27.9 0.1 0.0011 18.6 0.0 2.7 3 0 0 3 3 3 2 UvrD/REP helicase N-terminal domain ResIII PF04851.15 EWM21295.1 - 1.3e-05 25.3 0.0 2.8e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 EWM21295.1 - 0.00069 19.5 0.1 0.0013 18.6 0.1 1.6 1 1 0 1 1 1 1 Helicase PIF1 PF05970.14 EWM21295.1 - 0.00079 18.7 0.1 0.66 9.1 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase DUF2075 PF09848.9 EWM21295.1 - 0.0014 17.9 0.1 0.0034 16.7 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Flavi_DEAD PF07652.14 EWM21295.1 - 0.0062 16.5 0.1 0.013 15.5 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain PhoH PF02562.16 EWM21295.1 - 0.011 15.2 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EWM21295.1 - 0.017 14.7 0.0 0.05 13.2 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.7 EWM21295.1 - 0.026 13.5 0.0 0.042 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain ATPase PF06745.13 EWM21295.1 - 0.033 13.5 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 KaiC DEAD PF00270.29 EWM21295.1 - 0.052 13.3 0.2 0.095 12.5 0.2 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase NACHT PF05729.12 EWM21295.1 - 0.067 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 EWM21295.1 - 0.12 12.7 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EWM21295.1 - 0.12 12.8 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EWM21295.1 - 0.13 12.7 1.0 0.24 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain FANCA_interact PF15751.5 EWM21297.1 - 0.0053 17.2 0.2 0.018 15.5 0.2 1.8 2 0 0 2 2 2 1 FAAP20 FANCA interaction domain Thaumatin PF00314.17 EWM21297.1 - 0.022 14.4 0.1 0.022 14.4 0.1 1.5 2 0 0 2 2 2 0 Thaumatin family CybS PF05328.12 EWM21298.1 - 5.5e-12 45.5 0.0 6.8e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit ARID PF01388.21 EWM21300.1 - 7.1e-10 39.4 0.0 1.1e-09 38.9 0.0 1.3 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjC PF02373.22 EWM21302.1 - 2e-20 73.3 0.0 3.7e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 EWM21302.1 - 0.0001 22.1 4.5 0.00022 21.0 4.5 1.6 1 1 0 1 1 1 1 PHD-finger C1_1 PF00130.22 EWM21302.1 - 0.096 12.6 0.2 0.23 11.4 0.2 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) dUTPase PF00692.19 EWM21304.1 - 1.4e-38 131.5 0.0 2e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 dUTPase PADR1 PF08063.12 EWM21305.1 - 0.024 14.4 0.1 0.038 13.8 0.1 1.2 1 0 0 1 1 1 0 PADR1 (NUC008) domain KASH PF10541.9 EWM21306.1 - 1.7 9.0 7.9 0.79 10.0 1.4 2.9 3 0 0 3 3 3 0 Nuclear envelope localisation domain UPF0020 PF01170.18 EWM21307.1 - 3.1e-12 46.6 0.0 2.8e-10 40.2 0.1 2.6 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 EWM21307.1 - 5e-06 26.4 0.0 5.1e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 DNA methylase N6_Mtase PF02384.16 EWM21307.1 - 0.0066 15.7 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_10 PF05971.12 EWM21307.1 - 0.084 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 RNA methyltransferase Cys_Met_Meta_PP PF01053.20 EWM21308.1 - 1e-76 258.0 0.0 1.3e-76 257.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Glyco_transf_7C PF02709.14 EWM21309.1 - 1.7e-20 72.4 0.3 3e-20 71.7 0.3 1.3 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 EWM21309.1 - 2.1e-11 43.6 0.0 5.7e-09 35.7 0.0 2.4 2 0 0 2 2 2 2 N-terminal region of glycosyl transferase group 7 Lon_C PF05362.13 EWM21310.1 - 1.9e-43 148.4 12.8 1.8e-35 122.3 2.8 3.9 3 1 0 3 3 3 3 Lon protease (S16) C-terminal proteolytic domain ChlI PF13541.6 EWM21310.1 - 2.8e-05 23.9 0.3 0.00014 21.7 0.1 2.1 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase Cofac_haem_bdg PF04187.13 EWM21311.1 - 3.7e-32 112.1 0.0 5.7e-32 111.4 0.0 1.3 1 0 0 1 1 1 1 Haem-binding uptake, Tiki superfamily, ChaN SAM_decarbox PF01536.16 EWM21312.1 - 5.3e-94 315.1 0.0 6.9e-94 314.8 0.0 1.1 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Myc_N PF01056.18 EWM21312.1 - 0.34 10.8 2.6 0.53 10.1 2.6 1.2 1 0 0 1 1 1 0 Myc amino-terminal region ABC1 PF03109.16 EWM21313.1 - 3.7e-29 101.3 0.0 6.5e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 ABC1 family DUF2009 PF09418.10 EWM21314.1 - 1.4e-152 509.0 0.0 3.9e-118 395.4 0.0 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF2009) zf-B_box PF00643.24 EWM21314.1 - 0.0012 19.0 2.9 0.002 18.2 2.9 1.4 1 0 0 1 1 1 1 B-box zinc finger CEBP_ZZ PF16366.5 EWM21314.1 - 0.01 16.0 4.0 0.022 15.0 4.0 1.4 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain DUF2236 PF09995.9 EWM21314.1 - 0.14 12.3 5.0 0.37 11.0 5.0 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2236) Aldedh PF00171.22 EWM21315.1 - 1.5e-147 491.8 0.0 2.3e-107 359.4 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Ribosomal_L34 PF00468.17 EWM21315.1 - 0.12 12.4 1.0 0.28 11.2 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein L34 Cullin PF00888.22 EWM21316.1 - 2.2e-09 36.5 0.0 3.4e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 EWM21316.1 - 7.2e-08 32.8 0.0 1.9e-07 31.5 0.0 1.7 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 DUF5457 PF17540.2 EWM21316.1 - 0.11 12.7 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5457) DUF1356 PF07092.12 EWM21317.1 - 1.9e-07 30.6 0.1 2.8e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) DUF4805 PF16063.5 EWM21317.1 - 0.014 14.8 1.9 0.035 13.4 1.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) Chol_subst-bind PF09129.11 EWM21317.1 - 0.06 12.3 0.0 0.089 11.7 0.0 1.2 1 0 0 1 1 1 0 Cholesterol oxidase, substrate-binding DUF2890 PF11081.8 EWM21317.1 - 0.1 12.7 1.9 0.21 11.7 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) LSM PF01423.22 EWM21320.1 - 5.4e-15 54.8 0.1 7.8e-15 54.3 0.1 1.3 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EWM21320.1 - 0.02 14.6 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Hfq protein PCI PF01399.27 EWM21321.1 - 5.3e-10 39.8 0.0 1.2e-09 38.6 0.0 1.6 1 0 0 1 1 1 1 PCI domain Kin17_mid PF10357.9 EWM21322.1 - 2.7e-44 150.1 1.6 2.7e-44 150.1 1.6 1.9 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 EWM21322.1 - 7.1e-23 80.5 0.4 5.1e-22 77.7 0.2 2.3 2 0 0 2 2 2 1 KN17 SH3-like C-terminal domain TFIID_NTD2 PF04494.15 EWM21322.1 - 0.0053 17.0 0.1 0.014 15.6 0.1 1.7 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain DUF3811 PF11656.8 EWM21322.1 - 0.16 12.4 5.6 3 8.3 1.1 2.5 2 0 0 2 2 2 0 YjbD family (DUF3811) zf-C2H2_jaz PF12171.8 EWM21322.1 - 0.51 10.7 6.9 0.23 11.8 4.1 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding KOW PF00467.29 EWM21322.1 - 1 9.4 4.3 0.93 9.5 0.1 2.7 2 1 0 2 2 2 0 KOW motif zf-met PF12874.7 EWM21322.1 - 1.3 9.5 14.3 0.054 13.9 5.7 2.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EWM21322.1 - 9.8 6.6 9.0 0.59 10.5 2.4 2.3 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) DEAD PF00270.29 EWM21323.1 - 1.6e-44 151.7 0.1 2.6e-44 151.1 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EWM21323.1 - 3.1e-33 114.4 0.1 4.5e-32 110.7 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EWM21323.1 - 8.3e-06 25.9 0.0 2.5e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EWM21323.1 - 0.0016 18.2 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EWM21323.1 - 0.0094 16.3 0.1 0.039 14.3 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EWM21323.1 - 0.035 14.4 0.2 0.14 12.4 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EWM21323.1 - 0.035 13.6 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region CMS1 PF14617.6 EWM21323.1 - 0.035 13.4 0.0 0.071 12.4 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF2075 PF09848.9 EWM21323.1 - 0.04 13.1 0.0 0.066 12.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 EWM21323.1 - 0.072 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Helicase TniB PF05621.11 EWM21323.1 - 0.11 12.0 0.0 0.34 10.3 0.0 1.8 1 0 0 1 1 1 0 Bacterial TniB protein Sulfotransfer_1 PF00685.27 EWM21324.1 - 8.7e-37 127.0 0.0 2.2e-27 96.2 0.0 2.4 2 1 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EWM21324.1 - 2.9e-12 47.4 0.0 4.8e-08 33.7 0.0 2.3 2 0 0 2 2 2 2 Sulfotransferase family RMP PF14996.6 EWM21324.1 - 0.058 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Retinal Maintenance DP PF08781.10 EWM21325.1 - 8.6e-28 97.0 4.7 2.2e-18 66.5 0.1 2.4 2 0 0 2 2 2 2 Transcription factor DP E2F_TDP PF02319.20 EWM21325.1 - 2.2e-24 85.3 0.1 5e-24 84.2 0.1 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain CENP-F_leu_zip PF10473.9 EWM21325.1 - 0.017 15.1 3.2 0.035 14.1 3.2 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GFO_IDH_MocA PF01408.22 EWM21326.1 - 2.5e-20 73.5 0.0 4.5e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EWM21326.1 - 0.00035 20.6 0.0 0.00067 19.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Shikimate_DH PF01488.20 EWM21326.1 - 0.0016 18.5 0.0 0.0027 17.8 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 EWM21326.1 - 0.051 13.7 0.0 0.088 12.9 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus CoA_binding PF02629.19 EWM21326.1 - 0.066 13.9 0.0 0.2 12.3 0.0 1.7 2 0 0 2 2 2 0 CoA binding domain Pkinase PF00069.25 EWM21327.1 - 5.5e-62 209.5 0.0 2.5e-61 207.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM21327.1 - 3e-34 118.5 0.0 5.1e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EWM21327.1 - 0.00014 21.2 0.0 1.5 8.0 0.0 3.1 3 0 0 3 3 3 2 Kinase-like zf-C2H2_3rep PF18868.1 EWM21327.1 - 0.00061 20.5 0.1 0.0015 19.2 0.1 1.6 1 0 0 1 1 1 1 Zinc finger C2H2-type, 3 repeats Kdo PF06293.14 EWM21327.1 - 0.0044 16.4 0.0 0.0071 15.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-B_box PF00643.24 EWM21327.1 - 0.012 15.8 6.0 0.022 14.9 6.0 1.4 1 0 0 1 1 1 0 B-box zinc finger Pkinase_fungal PF17667.1 EWM21327.1 - 0.06 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase CEBP_ZZ PF16366.5 EWM21327.1 - 0.54 10.5 5.3 1.1 9.6 5.3 1.5 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain AAA_5 PF07728.14 EWM21329.1 - 9.4e-26 90.5 0.0 1.5e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) WD40 PF00400.32 EWM21329.1 - 4.5e-05 24.1 0.0 0.0052 17.6 0.0 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM21329.1 - 0.015 15.6 0.0 1.6 9.1 0.0 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain AAA_5 PF07728.14 EWM21330.1 - 3.1e-23 82.3 0.1 5.2e-23 81.6 0.1 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EWM21330.1 - 3.3e-06 27.6 0.4 0.00037 20.9 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 EWM21330.1 - 0.00069 19.8 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EWM21330.1 - 0.00096 19.4 0.1 0.032 14.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EWM21330.1 - 0.004 16.6 0.1 0.022 14.1 0.0 2.0 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EWM21330.1 - 0.015 14.8 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 EWM21330.1 - 0.021 14.7 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 EWM21330.1 - 0.044 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 EWM21330.1 - 0.052 13.3 0.1 0.097 12.4 0.1 1.4 1 1 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 EWM21330.1 - 0.067 12.5 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.6 EWM21330.1 - 0.075 13.1 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 EWM21330.1 - 0.16 12.2 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_3 PF07726.11 EWM21330.1 - 0.19 11.6 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Glyco_hydro_1 PF00232.18 EWM21332.1 - 1.3e-174 580.9 0.9 1.7e-174 580.5 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 HEAT PF02985.22 EWM21335.1 - 1.6e-21 74.5 15.1 0.00024 21.1 0.1 7.7 7 0 0 7 7 7 5 HEAT repeat HEAT_2 PF13646.6 EWM21335.1 - 1.6e-12 47.6 14.1 1.1e-05 25.7 0.7 5.2 2 1 3 6 6 6 4 HEAT repeats HEAT_EZ PF13513.6 EWM21335.1 - 7.6e-09 35.9 10.5 0.0033 17.9 2.1 5.3 4 1 2 6 6 6 2 HEAT-like repeat CLASP_N PF12348.8 EWM21335.1 - 0.00072 19.2 0.0 1.1 8.8 0.0 3.1 1 1 0 2 2 2 2 CLASP N terminal Cnd1 PF12717.7 EWM21335.1 - 0.00082 19.5 0.5 1.2 9.2 0.0 2.7 1 1 2 3 3 3 3 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 EWM21335.1 - 0.01 15.8 1.1 8.6 6.6 0.1 3.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DNA_alkylation PF08713.11 EWM21335.1 - 0.016 14.9 0.1 1.8 8.3 0.0 3.3 2 2 2 4 4 4 0 DNA alkylation repair enzyme Vac14_Fab1_bd PF12755.7 EWM21335.1 - 0.016 15.7 0.0 3.6 8.3 0.0 3.2 1 1 2 3 3 3 0 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 EWM21335.1 - 0.14 10.7 0.4 0.45 9.0 0.2 1.7 1 1 0 1 1 1 0 Adaptin N terminal region JAB PF01398.21 EWM21337.1 - 0.018 15.0 0.0 0.04 13.9 0.0 1.6 1 1 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease HNH_5 PF14279.6 EWM21340.1 - 3.9e-14 52.2 0.3 8e-14 51.2 0.3 1.5 1 0 0 1 1 1 1 HNH endonuclease HNH PF01844.23 EWM21340.1 - 5.4e-11 42.5 0.5 1.3e-10 41.2 0.5 1.7 2 0 0 2 2 2 1 HNH endonuclease HNH_4 PF13395.6 EWM21340.1 - 4.1e-07 29.8 0.0 9.4e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease TT_ORF2 PF02957.15 EWM21340.1 - 0.066 14.1 6.2 4.1 8.3 0.1 3.2 3 0 0 3 3 3 0 TT viral ORF2 FbpA PF05833.11 EWM21341.1 - 1.9e-62 211.6 0.0 1.1e-51 176.1 0.0 2.2 2 0 0 2 2 2 2 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 EWM21341.1 - 1e-09 39.0 0.0 2e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-R_2 PF18297.1 EWM21341.1 - 5.5e-05 23.3 0.0 0.00016 21.8 0.0 1.7 1 0 0 1 1 1 1 NFACT protein RNA binding domain HAGH_C PF16123.5 EWM21343.1 - 1.2e-23 83.4 0.0 1.8e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 EWM21343.1 - 3e-09 37.2 3.5 3e-08 33.9 3.5 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EWM21343.1 - 0.0052 16.3 0.1 0.0095 15.5 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DoxX PF07681.12 EWM21343.1 - 0.011 16.3 0.2 0.061 13.9 0.1 2.1 2 0 0 2 2 2 0 DoxX FIST PF08495.10 EWM21343.1 - 0.14 12.2 0.2 0.44 10.5 0.0 1.6 1 1 0 1 1 1 0 FIST N domain Bromodomain PF00439.25 EWM21344.1 - 3.9e-10 39.6 0.0 7.9e-05 22.7 0.0 2.3 2 0 0 2 2 2 2 Bromodomain PHD PF00628.29 EWM21344.1 - 3.6e-06 26.8 0.7 3.6e-06 26.8 0.7 3.4 3 0 0 3 3 3 1 PHD-finger DUF4442 PF14539.6 EWM21345.1 - 6.2e-32 110.5 0.2 7.7e-32 110.2 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) adh_short_C2 PF13561.6 EWM21346.1 - 0.0092 15.6 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EWM21346.1 - 0.012 15.1 0.6 0.049 13.1 0.0 2.0 2 0 0 2 2 2 0 short chain dehydrogenase Kelch_2 PF07646.15 EWM21346.1 - 0.11 12.5 0.3 3.7 7.7 0.1 2.5 2 0 0 2 2 2 0 Kelch motif Ank_2 PF12796.7 EWM21347.1 - 4.6e-25 88.0 0.0 3.7e-10 40.3 0.0 3.8 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 EWM21347.1 - 3.6e-20 71.4 0.3 4.3e-06 26.9 0.1 6.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 EWM21347.1 - 7.3e-18 64.7 0.2 3.8e-07 30.5 0.0 5.0 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EWM21347.1 - 4.5e-17 60.4 1.5 0.00014 22.0 0.0 6.1 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 EWM21347.1 - 1.5e-12 47.5 1.3 0.0021 18.3 0.0 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) UAA PF08449.11 EWM21348.1 - 2.9e-65 220.5 13.2 3.4e-65 220.2 13.2 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EWM21348.1 - 4.6e-13 49.5 21.5 1.4e-08 35.0 8.6 2.4 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 EWM21348.1 - 5e-08 32.5 5.4 0.00058 19.1 1.8 2.5 2 1 1 3 3 3 2 Nucleotide-sugar transporter TPT PF03151.16 EWM21348.1 - 0.0033 16.8 8.3 0.1 11.9 0.6 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family SPC12 PF06645.13 EWM21348.1 - 0.038 14.1 1.3 18 5.5 0.0 3.3 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) SAP PF02037.27 EWM21349.1 - 4.1e-11 42.4 1.7 4.1e-11 42.4 1.7 1.9 2 0 0 2 2 2 1 SAP domain RSB_motif PF16294.5 EWM21349.1 - 1e-10 41.8 1.1 1e-10 41.8 1.1 2.1 2 0 0 2 2 2 1 RNSP1-SAP18 binding (RSB) motif RNase_PH PF01138.21 EWM21351.1 - 3.1e-19 69.8 0.0 9.8e-19 68.2 0.0 1.9 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EWM21351.1 - 9.8e-10 38.3 1.4 1.7e-09 37.6 0.0 2.0 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 CAF1-p150_C2 PF15539.6 EWM21351.1 - 0.14 11.6 2.9 0.23 10.9 2.9 1.3 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term Myc_N PF01056.18 EWM21351.1 - 0.35 10.7 4.2 0.27 11.1 2.7 1.5 1 1 0 1 1 1 0 Myc amino-terminal region Proteasome PF00227.26 EWM21352.1 - 2e-27 95.9 0.6 5.5e-27 94.5 0.6 1.7 1 1 0 1 1 1 1 Proteasome subunit P5CR_dimer PF14748.6 EWM21352.1 - 0.014 15.6 1.0 0.028 14.7 1.0 1.5 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation ABG_transport PF03806.13 EWM21352.1 - 0.19 9.9 0.0 0.29 9.3 0.0 1.2 1 0 0 1 1 1 0 AbgT putative transporter family HHV-5_US34A PF17087.5 EWM21352.1 - 0.2 11.8 2.3 0.8 9.9 0.9 2.4 2 0 0 2 2 2 0 Herpesvirus US34A protein family Cript PF10235.9 EWM21354.1 - 4.4e-21 75.3 2.6 4.4e-21 75.3 2.6 1.5 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT DUF2039 PF10217.9 EWM21354.1 - 0.018 15.4 5.4 0.018 15.4 5.4 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Rhodanese_C PF12368.8 EWM21354.1 - 0.39 11.1 9.0 0.54 10.7 2.4 2.1 2 0 0 2 2 2 0 Rhodanase C-terminal zf-piccolo PF05715.13 EWM21354.1 - 6.6 7.0 9.2 2 8.6 3.6 2.3 2 0 0 2 2 2 0 Piccolo Zn-finger ubiquitin PF00240.23 EWM21355.1 - 5.4e-06 26.1 0.0 9.5e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EWM21355.1 - 0.0066 16.3 0.0 0.021 14.7 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Pox_A6 PF04924.12 EWM21355.1 - 0.22 10.5 0.1 0.3 10.0 0.1 1.1 1 0 0 1 1 1 0 Poxvirus A6 protein LRR_1 PF00560.33 EWM21356.1 - 0.0023 18.2 18.4 7.3 7.6 0.0 8.0 9 0 0 9 9 9 2 Leucine Rich Repeat LRR_6 PF13516.6 EWM21356.1 - 0.012 15.6 15.7 3.8 7.8 0.2 6.8 7 0 0 7 7 7 0 Leucine Rich repeat LRR_4 PF12799.7 EWM21356.1 - 0.065 13.7 12.3 1.1 9.8 0.0 5.2 5 2 1 6 6 6 0 Leucine Rich repeats (2 copies) MutS_V PF00488.21 EWM21358.1 - 1e-68 231.1 0.1 2.2e-68 230.0 0.0 1.7 2 0 0 2 2 2 1 MutS domain V MutS_IV PF05190.18 EWM21358.1 - 1.5e-08 34.8 0.0 2.6e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 MutS family domain IV MutS_III PF05192.18 EWM21358.1 - 1.6e-08 35.0 0.4 2.1e-07 31.4 0.4 2.4 1 1 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EWM21358.1 - 0.0036 17.5 0.0 0.0084 16.3 0.0 1.6 1 0 0 1 1 1 1 MutS domain I M16C_assoc PF08367.11 EWM21358.1 - 0.32 10.1 1.3 0.56 9.3 1.3 1.3 1 0 0 1 1 1 0 Peptidase M16C associated Ank_2 PF12796.7 EWM21359.1 - 3.6e-34 117.2 0.0 3.8e-13 49.8 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EWM21359.1 - 9.2e-27 93.1 1.5 5.2e-11 42.9 0.1 4.4 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EWM21359.1 - 2.4e-26 88.9 0.2 5.6e-05 23.2 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EWM21359.1 - 5.8e-26 90.2 1.2 1.1e-08 35.2 0.0 5.3 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EWM21359.1 - 7.5e-23 79.9 1.3 0.00012 22.4 0.0 4.8 5 0 0 5 5 5 4 Ankyrin repeat Complex1_LYR PF05347.15 EWM21366.1 - 2.1e-15 56.5 1.1 2.1e-15 56.5 1.1 1.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EWM21366.1 - 0.00063 20.4 1.9 0.00092 19.9 1.9 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 EWM21366.1 - 0.0027 18.3 1.8 0.004 17.7 1.8 1.3 1 0 0 1 1 1 1 Complex1_LYR-like CNH PF00780.22 EWM21366.1 - 0.032 13.9 0.4 0.038 13.6 0.4 1.1 1 0 0 1 1 1 0 CNH domain PfkB PF00294.24 EWM21371.1 - 1.7e-08 34.1 0.0 5.2e-07 29.3 0.0 2.8 2 1 0 2 2 2 1 pfkB family carbohydrate kinase Glyco_transf_34 PF05637.12 EWM21373.1 - 0.037 13.8 0.0 3.4 7.3 0.0 2.1 2 0 0 2 2 2 0 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 EWM21373.1 - 0.057 13.0 0.0 0.13 11.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function, DUF273 DHQ_synthase PF01761.20 EWM21378.1 - 3.2e-105 351.0 0.0 3.9e-105 350.8 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 EWM21378.1 - 1e-11 45.0 0.1 3.3e-11 43.4 0.1 1.8 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 EWM21378.1 - 2.2e-06 26.7 0.7 4.1e-06 25.9 0.2 1.6 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase WD40 PF00400.32 EWM21379.1 - 2e-12 47.4 14.2 0.00059 20.6 0.1 6.6 6 1 0 6 6 6 3 WD domain, G-beta repeat ABC_tran PF00005.27 EWM21381.1 - 1.5e-34 119.5 0.0 1e-33 116.7 0.0 2.2 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 EWM21381.1 - 9.6e-31 107.4 1.4 1.2e-30 107.1 1.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EWM21381.1 - 1.9e-07 30.7 0.1 1.8e-05 24.3 0.1 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EWM21381.1 - 3.1e-05 24.4 0.2 0.00034 21.0 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 EWM21381.1 - 0.00096 19.0 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EWM21381.1 - 0.0021 18.3 0.1 0.009 16.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EWM21381.1 - 0.0063 16.4 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_24 PF13479.6 EWM21381.1 - 0.007 16.1 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EWM21381.1 - 0.015 15.0 0.0 0.097 12.4 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain NACHT PF05729.12 EWM21381.1 - 0.033 14.1 0.0 0.24 11.3 0.0 2.1 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 EWM21381.1 - 0.036 14.1 0.0 0.22 11.6 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF903 PF06004.12 EWM21381.1 - 0.039 13.8 0.1 0.079 12.9 0.1 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF903) Zeta_toxin PF06414.12 EWM21381.1 - 0.044 13.1 0.0 0.16 11.2 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.6 EWM21381.1 - 0.05 13.8 0.3 0.59 10.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 EWM21381.1 - 0.052 13.3 0.0 0.11 12.1 0.0 1.5 2 0 0 2 2 1 0 AAA ATPase domain AAA_33 PF13671.6 EWM21381.1 - 0.058 13.6 0.0 0.28 11.3 0.0 2.2 2 0 0 2 2 1 0 AAA domain DUF815 PF05673.13 EWM21381.1 - 0.071 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_ATPase PF09818.9 EWM21381.1 - 0.077 11.8 0.0 0.88 8.3 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_14 PF13173.6 EWM21381.1 - 0.077 13.0 0.0 0.3 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EWM21381.1 - 0.081 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain IstB_IS21 PF01695.17 EWM21381.1 - 0.1 12.4 0.1 6.4 6.5 0.0 2.6 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_18 PF13238.6 EWM21381.1 - 0.11 13.0 0.0 0.32 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EWM21381.1 - 0.2 12.1 0.0 1.3 9.4 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.6 EWM21381.1 - 0.24 11.9 0.8 1.1 9.8 0.0 2.3 2 1 1 3 3 2 0 AAA domain RAWUL PF16207.5 EWM21383.1 - 2.8e-06 27.9 0.0 2e-05 25.2 0.0 2.1 1 1 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like PfkB PF00294.24 EWM21385.1 - 7.3e-67 225.8 0.4 9.3e-67 225.5 0.4 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Flavi_NS2B PF01002.19 EWM21387.1 - 0.095 12.6 0.1 0.18 11.7 0.0 1.5 2 0 0 2 2 2 0 Flavivirus non-structural protein NS2B LEA_4 PF02987.16 EWM21387.1 - 0.096 12.8 2.4 0.35 11.0 2.4 1.8 1 1 0 1 1 1 0 Late embryogenesis abundant protein Flavi_NS2B PF01002.19 EWM21388.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2B LEA_4 PF02987.16 EWM21388.1 - 0.12 12.4 2.9 0.46 10.6 2.9 1.8 1 1 0 1 1 1 0 Late embryogenesis abundant protein Cyt-b5 PF00173.28 EWM21389.1 - 2.3e-13 50.1 0.0 4.5e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain F-box-like PF12937.7 EWM21389.1 - 1e-05 25.3 0.0 2.3e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EWM21389.1 - 0.00021 21.1 0.0 0.00044 20.0 0.0 1.6 1 0 0 1 1 1 1 F-box domain APH PF01636.23 EWM21389.1 - 2.1 8.2 10.3 3.7 7.4 1.2 2.5 2 1 0 2 2 2 0 Phosphotransferase enzyme family TAL_FSA PF00923.19 EWM21391.1 - 1.8e-14 53.8 0.0 2.3e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase DUF1681 PF07933.14 EWM21392.1 - 4.3e-31 107.6 0.0 5.8e-31 107.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) IKI3 PF04762.12 EWM21395.1 - 9.2e-39 133.2 0.0 1e-38 133.0 0.0 1.0 1 0 0 1 1 1 1 IKI3 family PPR_2 PF13041.6 EWM21396.1 - 4.9e-91 298.8 0.0 1.4e-10 41.1 0.1 15.5 6 4 11 17 17 17 15 PPR repeat family PPR PF01535.20 EWM21396.1 - 2.7e-71 231.0 16.4 4.4e-07 29.7 0.0 18.3 18 0 0 18 18 18 13 PPR repeat PPR_3 PF13812.6 EWM21396.1 - 1.6e-65 217.1 0.0 3.7e-11 42.9 0.0 11.6 7 3 7 15 15 15 11 Pentatricopeptide repeat domain PPR_1 PF12854.7 EWM21396.1 - 1.8e-46 155.5 0.6 2.2e-07 30.4 0.0 14.2 15 0 0 15 15 15 7 PPR repeat PPR_long PF17177.4 EWM21396.1 - 8e-30 103.8 0.0 2.5e-09 36.8 0.0 6.0 2 1 3 6 6 6 5 Pentacotripeptide-repeat region of PRORP Smr PF01713.21 EWM21396.1 - 1e-06 29.0 0.0 3.3e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 Smr domain TPR_14 PF13428.6 EWM21396.1 - 2.1e-05 24.9 13.9 1.5 9.8 0.1 8.1 6 1 2 8 8 7 1 Tetratricopeptide repeat ECSIT PF06239.11 EWM21396.1 - 0.0062 15.7 0.0 27 3.8 0.0 4.3 4 0 0 4 4 4 0 Evolutionarily conserved signalling intermediate in Toll pathway Clathrin PF00637.20 EWM21396.1 - 0.024 14.5 0.0 9.9 6.0 0.0 3.7 4 0 0 4 4 4 0 Region in Clathrin and VPS TPR_1 PF00515.28 EWM21396.1 - 0.028 14.3 0.7 20 5.2 0.3 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EWM21396.1 - 0.14 12.5 7.6 35 4.8 0.2 6.2 7 1 0 7 7 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 EWM21396.1 - 0.17 12.0 8.8 8.7 6.7 0.6 5.2 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EWM21396.1 - 3 8.7 8.2 26 5.7 0.0 6.0 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 EWM21396.1 - 4.6 8.0 12.6 1.3 9.7 0.7 5.6 6 1 0 6 6 6 0 Tetratricopeptide repeat APG6 PF04111.12 EWM21397.1 - 2.7e-06 27.5 0.0 5.5e-05 23.2 0.0 2.3 2 1 0 2 2 2 1 Apg6 BARA domain APG6_N PF17675.1 EWM21397.1 - 0.00011 22.7 6.7 0.00034 21.1 6.7 1.8 1 1 0 1 1 1 1 Apg6 coiled-coil region OB_NTP_bind PF07717.16 EWM21397.1 - 0.085 13.2 0.1 0.23 11.8 0.1 1.7 1 0 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold Troponin PF00992.20 EWM21397.1 - 1.3 9.3 6.9 2.3 8.5 6.9 1.3 1 0 0 1 1 1 0 Troponin APG6 PF04111.12 EWM21398.1 - 2.7e-06 27.4 0.0 5.6e-05 23.2 0.0 2.3 2 1 0 2 2 2 1 Apg6 BARA domain APG6_N PF17675.1 EWM21398.1 - 0.00011 22.8 6.6 0.00032 21.2 6.6 1.9 1 1 0 1 1 1 1 Apg6 coiled-coil region OB_NTP_bind PF07717.16 EWM21398.1 - 0.085 13.2 0.1 0.23 11.8 0.1 1.7 1 0 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold Troponin PF00992.20 EWM21398.1 - 1.3 9.3 6.9 2.3 8.5 6.9 1.3 1 0 0 1 1 1 0 Troponin ABC2_membrane PF01061.24 EWM21399.1 - 2.6e-34 118.5 17.7 4.1e-34 117.8 17.7 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EWM21399.1 - 0.0001 22.8 0.0 0.00015 22.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter PDR_assoc PF08370.11 EWM21399.1 - 0.44 10.3 0.0 0.44 10.3 0.0 2.7 2 1 1 3 3 3 0 Plant PDR ABC transporter associated ABC2_membrane_3 PF12698.7 EWM21399.1 - 0.47 9.5 28.0 0.081 12.0 15.2 2.1 1 1 1 2 2 2 0 ABC-2 family transporter protein DUF809 PF05663.11 EWM21399.1 - 2.8 8.1 7.8 5 7.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF809) Proteasome PF00227.26 EWM21400.1 - 4.8e-56 189.3 0.0 8.1e-56 188.5 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EWM21400.1 - 2.1e-13 49.6 0.0 4e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ADH_zinc_N PF00107.26 EWM21400.1 - 1.4e-05 25.1 0.0 3.2e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Cep57_MT_bd PF06657.13 EWM21401.1 - 0.04 14.4 1.7 0.04 14.4 1.7 2.4 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 APG6_N PF17675.1 EWM21401.1 - 6.8 7.2 9.6 0.62 10.6 4.8 1.7 2 0 0 2 2 2 0 Apg6 coiled-coil region ABC2_membrane PF01061.24 EWM21402.1 - 7e-35 120.4 17.9 1.2e-34 119.5 17.9 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EWM21402.1 - 1.6e-15 57.8 0.0 2.6e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EWM21402.1 - 7.2e-06 25.3 13.8 9.9e-06 24.9 13.8 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 EWM21402.1 - 9e-05 22.4 0.5 0.0078 16.1 0.2 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EWM21402.1 - 0.00034 20.3 1.1 0.0014 18.3 0.1 2.5 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_25 PF13481.6 EWM21402.1 - 0.0023 17.5 0.0 0.0055 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EWM21402.1 - 0.026 14.4 0.1 0.043 13.7 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 EWM21402.1 - 0.029 14.8 0.2 0.061 13.7 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EWM21402.1 - 0.04 14.2 0.0 0.16 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EWM21402.1 - 0.069 13.4 0.7 0.13 12.5 0.7 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EWM21402.1 - 0.097 12.6 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 EWM21402.1 - 0.18 12.0 1.0 0.29 11.3 0.1 1.9 2 0 0 2 2 2 0 AAA domain PDR_CDR PF06422.12 EWM21402.1 - 2.8 7.9 8.4 0.14 12.1 0.4 2.3 2 0 0 2 2 2 0 CDR ABC transporter FKBP_C PF00254.28 EWM21403.1 - 3.6e-22 78.5 0.0 6.5e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Sacchrp_dh_C PF16653.5 EWM21404.1 - 2.1e-67 228.1 0.0 2.7e-67 227.7 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 EWM21404.1 - 1.2e-14 54.6 0.0 2e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Saccharop_dh_N PF04455.12 EWM21404.1 - 2.4e-12 47.1 0.0 6.4e-12 45.8 0.0 1.7 2 0 0 2 2 2 1 LOR/SDH bifunctional enzyme conserved region TrkA_N PF02254.18 EWM21404.1 - 0.015 15.6 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain DAGAT PF03982.13 EWM21405.1 - 1.5e-37 129.1 0.0 2.5e-37 128.4 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase AlaDh_PNT_N PF05222.15 EWM21406.1 - 7.4e-23 81.4 0.0 1.4e-22 80.4 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain Pkinase_Tyr PF07714.17 EWM21408.1 - 0.0028 17.0 0.0 0.022 14.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EWM21408.1 - 0.0072 15.7 0.0 0.017 14.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 EWM21409.1 - 2e-27 96.2 0.0 5.7e-27 94.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM21409.1 - 2.5e-24 86.0 0.0 1.1e-23 83.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EWM21409.1 - 2.7e-06 26.9 0.0 1.2e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EWM21409.1 - 7.6e-05 22.7 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EWM21409.1 - 0.0015 17.9 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EWM21409.1 - 0.0067 15.3 0.2 0.067 11.9 0.2 2.0 1 1 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EWM21409.1 - 0.07 12.1 0.0 0.08 11.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain 3HCDH_N PF02737.18 EWM21411.1 - 2.3e-56 190.5 0.3 4.1e-56 189.7 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 EWM21411.1 - 2.2e-39 135.3 0.1 3.2e-39 134.7 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EWM21411.1 - 2.2e-25 89.9 0.9 3.1e-25 89.4 0.0 1.7 3 0 0 3 3 3 1 Enoyl-CoA hydratase/isomerase NAD_binding_2 PF03446.15 EWM21411.1 - 0.0027 17.9 0.6 0.14 12.3 0.1 2.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH PF00725.22 EWM21411.1 - 0.035 14.7 0.3 0.64 10.7 0.0 2.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.23 EWM21411.1 - 0.05 13.6 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DAO PF01266.24 EWM21411.1 - 0.062 12.9 0.1 0.093 12.3 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EWM21411.1 - 0.097 12.9 0.9 0.21 11.8 0.4 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 EWM21411.1 - 0.14 11.7 0.1 0.29 10.7 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Radical_SAM PF04055.21 EWM21412.1 - 2.4e-11 44.3 0.0 4.4e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily LIAS_N PF16881.5 EWM21412.1 - 3.7e-07 30.5 0.0 8.2e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family zf-C3HC4 PF00097.25 EWM21413.1 - 2e-07 30.7 11.7 3.3e-07 30.1 11.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EWM21413.1 - 6.2e-07 29.1 12.7 1.1e-06 28.3 12.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EWM21413.1 - 1e-06 28.5 12.9 1.5e-06 28.0 12.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EWM21413.1 - 1.8e-05 25.0 12.8 2.9e-05 24.3 12.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EWM21413.1 - 0.00028 20.8 11.5 0.00049 20.0 11.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EWM21413.1 - 0.00074 19.6 8.6 0.0017 18.5 8.7 1.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EWM21413.1 - 0.002 18.1 10.7 0.0028 17.6 6.5 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EWM21413.1 - 0.016 15.3 5.9 0.024 14.7 5.9 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EWM21413.1 - 0.3 11.4 10.3 0.74 10.2 10.3 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EWM21413.1 - 0.86 9.5 12.3 2.1 8.3 12.3 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Gtr1_RagA PF04670.12 EWM21414.1 - 5.6e-56 189.5 0.0 9e-38 129.9 0.1 2.1 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 EWM21414.1 - 0.00039 20.8 0.0 0.0043 17.4 0.0 2.3 2 1 1 3 3 3 1 AAA ATPase domain Roc PF08477.13 EWM21414.1 - 0.0014 18.8 0.0 0.0027 17.9 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EWM21414.1 - 0.0018 17.7 0.0 0.0036 16.8 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 EWM21414.1 - 0.0048 16.9 0.0 0.0098 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Arf PF00025.21 EWM21414.1 - 0.038 13.4 0.0 6.5 6.2 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA PF00004.29 EWM21414.1 - 0.14 12.6 0.0 1.2 9.6 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FYRC PF05965.14 EWM21414.1 - 0.14 12.3 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 F/Y rich C-terminus Gtr1_RagA PF04670.12 EWM21415.1 - 1.9e-56 191.0 0.0 4.3e-38 131.0 0.1 2.0 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 EWM21415.1 - 0.00017 22.0 0.0 0.0028 18.0 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 EWM21415.1 - 0.00089 19.5 0.0 0.0017 18.5 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EWM21415.1 - 0.0012 18.3 0.0 0.0023 17.4 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 EWM21415.1 - 0.0032 17.5 0.0 0.0066 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Arf PF00025.21 EWM21415.1 - 0.016 14.7 0.0 4.2 6.8 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA PF00004.29 EWM21415.1 - 0.069 13.6 0.0 0.77 10.2 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FYRC PF05965.14 EWM21415.1 - 0.09 13.0 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 F/Y rich C-terminus Gtr1_RagA PF04670.12 EWM21416.1 - 1.9e-56 191.1 0.0 4.2e-38 131.0 0.1 2.0 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 EWM21416.1 - 0.00024 21.5 0.0 0.0043 17.4 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 EWM21416.1 - 0.00088 19.5 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EWM21416.1 - 0.0012 18.4 0.0 0.0023 17.4 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 EWM21416.1 - 0.0032 17.5 0.0 0.0064 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Arf PF00025.21 EWM21416.1 - 0.021 14.3 0.0 5.9 6.3 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA PF00004.29 EWM21416.1 - 0.067 13.6 0.0 0.76 10.2 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FYRC PF05965.14 EWM21416.1 - 0.088 13.0 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 F/Y rich C-terminus REV PF00424.18 EWM21417.1 - 0.019 15.0 2.8 0.031 14.3 2.8 1.4 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) HLH PF00010.26 EWM21417.1 - 0.022 14.7 0.6 0.046 13.7 0.6 1.6 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain DHHC PF01529.20 EWM21418.1 - 2.3e-19 69.8 8.8 2.3e-19 69.8 8.8 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase NPL4 PF05021.15 EWM21419.1 - 5.2e-26 91.7 0.0 2.6e-12 46.7 0.0 3.3 2 2 0 2 2 2 2 NPL4 family UN_NPL4 PF11543.8 EWM21419.1 - 8e-08 32.7 0.0 1.5e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 ubiquitin PF00240.23 EWM21419.1 - 4e-05 23.3 0.0 7.7e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Kazal_1 PF00050.21 EWM21419.1 - 0.017 15.1 0.1 0.035 14.1 0.1 1.4 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain YukD PF08817.10 EWM21419.1 - 0.036 14.8 0.0 0.086 13.5 0.0 1.7 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Rad60-SLD PF11976.8 EWM21419.1 - 0.17 11.7 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Kazal_2 PF07648.15 EWM21419.1 - 0.22 11.7 0.1 0.41 10.8 0.1 1.4 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain Pyridoxal_deC PF00282.19 EWM21420.1 - 4.7e-17 61.8 0.0 6.6e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.17 EWM21420.1 - 3.1e-08 33.3 0.4 4.5e-08 32.8 0.4 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EWM21420.1 - 3.4e-08 32.9 0.1 1.6e-07 30.6 0.1 1.8 1 1 0 1 1 1 1 Aminotransferase class-V MoCF_biosynth PF00994.24 EWM21421.1 - 1.7e-30 105.6 0.1 3.2e-30 104.7 0.1 1.5 1 0 0 1 1 1 1 Probable molybdopterin binding domain PAPS_reduct PF01507.19 EWM21421.1 - 4.6e-24 85.4 0.0 1.1e-16 61.4 0.0 2.5 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family DUF1737 PF08410.10 EWM21421.1 - 0.14 12.0 0.0 0.36 10.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1737) Glyco_transf_20 PF00982.21 EWM21423.1 - 8.6e-129 430.3 0.0 1.3e-128 429.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EWM21423.1 - 1.5e-44 151.9 0.0 3.4e-44 150.7 0.0 1.6 1 0 0 1 1 1 1 Trehalose-phosphatase CBM_20 PF00686.19 EWM21423.1 - 1.8e-12 47.0 0.0 4.7e-11 42.4 0.0 2.6 2 0 0 2 2 2 1 Starch binding domain Glycos_transf_1 PF00534.20 EWM21423.1 - 0.0016 18.0 0.1 4.4 6.8 0.0 3.1 2 1 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EWM21423.1 - 0.038 14.4 0.0 0.12 12.7 0.0 2.0 1 0 0 1 1 1 0 Glycosyl transferases group 1 SspH PF08141.12 EWM21423.1 - 0.085 13.0 1.7 0.26 11.4 0.0 2.5 3 0 0 3 3 3 0 Small acid-soluble spore protein H family LytR_C PF13399.6 EWM21423.1 - 0.11 13.5 0.0 0.47 11.5 0.0 2.1 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator Hydrolase_3 PF08282.12 EWM21423.1 - 0.13 11.9 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Cuticle_2 PF08184.11 EWM21423.1 - 1.1 9.3 2.9 0.45 10.5 0.1 1.8 2 0 0 2 2 2 0 Cuticle protein 7 isoform family Hydrolase_4 PF12146.8 EWM21424.1 - 5.5e-49 166.6 0.0 6.9e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EWM21424.1 - 1.9e-08 35.2 0.1 2.9e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EWM21424.1 - 9.6e-07 28.7 0.0 8e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EWM21424.1 - 0.009 15.9 0.0 0.025 14.4 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EWM21424.1 - 0.025 14.2 0.0 0.48 10.0 0.0 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Say1_Mug180 PF10340.9 EWM21424.1 - 0.19 10.5 0.0 0.3 9.9 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 EWM21425.1 - 5.5e-49 166.6 0.0 6.9e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EWM21425.1 - 1.9e-08 35.2 0.1 2.9e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EWM21425.1 - 9.6e-07 28.7 0.0 8e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EWM21425.1 - 0.009 15.9 0.0 0.025 14.4 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EWM21425.1 - 0.025 14.2 0.0 0.48 10.0 0.0 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Say1_Mug180 PF10340.9 EWM21425.1 - 0.19 10.5 0.0 0.3 9.9 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase RNA_pol_L_2 PF13656.6 EWM21426.1 - 1.3e-24 85.8 0.1 1.5e-24 85.5 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EWM21426.1 - 3.8e-06 26.2 0.0 5.3e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Tup_N PF08581.10 EWM21426.1 - 0.0097 16.2 0.3 0.014 15.6 0.3 1.3 1 0 0 1 1 1 1 Tup N-terminal RNA_pol_L_2 PF13656.6 EWM21427.1 - 2.4e-20 72.1 0.0 2.6e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EWM21427.1 - 0.0037 16.6 0.0 0.0044 16.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Mannosyl_trans3 PF11051.8 EWM21427.1 - 0.13 11.6 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Mannosyltransferase putative Mating_C PF12737.7 EWM21428.1 - 0.0011 18.3 5.7 0.0018 17.6 5.7 1.4 1 0 0 1 1 1 1 C-terminal domain of homeodomain 1 Pyr_redox_2 PF07992.14 EWM21431.1 - 3.3e-40 138.1 0.1 4.4e-40 137.8 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EWM21431.1 - 3e-17 62.8 0.0 7e-13 48.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thioredoxin PF00085.20 EWM21431.1 - 5.6e-14 52.0 0.0 1.3e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Pyr_redox PF00070.27 EWM21431.1 - 2.5e-11 44.0 0.0 6.4e-09 36.2 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EWM21431.1 - 1.2e-06 28.2 0.3 2.6e-05 23.8 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EWM21431.1 - 2.8e-06 26.7 2.1 1.6e-05 24.2 0.2 2.6 2 1 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 EWM21431.1 - 3.1e-06 26.6 0.5 1.4e-05 24.5 0.2 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 EWM21431.1 - 6.7e-06 26.3 2.1 2.5e-05 24.4 0.0 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EWM21431.1 - 0.00013 21.2 1.8 0.016 14.3 0.1 3.4 3 0 0 3 3 3 1 Glucose inhibited division protein A TraF PF13728.6 EWM21431.1 - 0.00022 21.1 0.0 0.00041 20.3 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein HI0933_like PF03486.14 EWM21431.1 - 0.00024 20.0 0.6 0.0035 16.1 0.1 2.5 3 0 0 3 3 3 1 HI0933-like protein Thioredoxin_7 PF13899.6 EWM21431.1 - 0.00073 19.7 0.0 0.0019 18.3 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.24 EWM21431.1 - 0.0035 17.5 0.0 0.01 16.0 0.0 1.9 1 0 0 1 1 1 1 Glutaredoxin K_oxygenase PF13434.6 EWM21431.1 - 0.0053 15.9 0.0 0.096 11.8 0.0 2.4 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thioredoxin_2 PF13098.6 EWM21431.1 - 0.0058 17.1 0.0 0.057 13.9 0.0 2.4 2 1 0 2 2 2 1 Thioredoxin-like domain DAO PF01266.24 EWM21431.1 - 0.014 15.0 3.2 0.82 9.2 0.5 2.7 2 1 1 3 3 3 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EWM21431.1 - 0.031 13.1 0.2 0.094 11.5 0.1 1.8 3 0 0 3 3 3 0 Tryptophan halogenase NAD_binding_9 PF13454.6 EWM21431.1 - 0.074 13.0 0.9 5.1 7.1 0.0 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding Polyketide_cyc PF03364.20 EWM21432.1 - 4.7e-12 46.3 0.2 9.9e-12 45.2 0.2 1.5 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 EWM21432.1 - 7.3e-11 42.5 0.2 1e-10 42.1 0.2 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport BROMI PF14961.6 EWM21433.1 - 8.7e-11 40.1 0.0 1.8e-05 22.4 0.0 2.4 2 1 0 2 2 2 2 Broad-minded protein Creb_binding PF09030.10 EWM21433.1 - 0.15 12.8 1.6 0.76 10.5 0.6 2.3 2 0 0 2 2 2 0 Creb binding HVSL PF09749.9 EWM21434.1 - 1.3e-15 57.6 0.0 2.6e-15 56.5 0.0 1.5 1 1 0 1 1 1 1 Uncharacterised conserved protein WD40 PF00400.32 EWM21435.1 - 2.7e-31 107.1 7.6 9.2e-08 32.6 0.1 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 EWM21435.1 - 7e-26 90.3 0.4 2e-25 88.8 0.2 1.9 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Mitofilin PF09731.9 EWM21436.1 - 1.3e-41 143.2 29.8 5.5e-40 137.8 29.8 2.0 1 1 0 1 1 1 1 Mitochondrial inner membrane protein Trns_repr_metal PF02583.17 EWM21436.1 - 0.0048 17.2 0.6 1.2 9.5 0.0 3.5 3 0 0 3 3 3 1 Metal-sensitive transcriptional repressor DUF2887 PF11103.8 EWM21436.1 - 0.059 13.4 1.1 0.13 12.2 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2887) zf-C4pol PF14260.6 EWM21437.1 - 1.7 9.1 8.5 3.9 8.0 0.9 2.2 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta C1_1 PF00130.22 EWM21437.1 - 9.6 6.2 14.9 0.53 10.2 4.0 2.9 1 1 2 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TFIIA PF03153.13 EWM21438.1 - 0.0026 17.8 2.9 0.0026 17.8 2.9 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit PPP4R2 PF09184.11 EWM21438.1 - 0.0037 16.9 12.4 0.0037 16.9 12.4 2.7 3 0 0 3 3 3 1 PPP4R2 Na_trans_assoc PF06512.13 EWM21438.1 - 0.65 10.2 16.3 0.1 12.9 9.8 2.3 2 0 0 2 2 2 0 Sodium ion transport-associated DUF2052 PF09747.9 EWM21438.1 - 0.75 9.9 30.0 0.2 11.7 18.1 2.9 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) AIF_C PF14721.6 EWM21438.1 - 1.1 9.6 4.5 3.3 8.1 4.5 1.9 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term FemAB PF02388.16 EWM21438.1 - 2.4 6.9 5.0 3.5 6.4 5.0 1.1 1 0 0 1 1 1 0 FemAB family DUF2151 PF10221.9 EWM21438.1 - 3.8 6.0 9.6 5.3 5.5 9.6 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator TERB2 PF15101.6 EWM21438.1 - 4.3 7.3 6.3 8.2 6.4 6.3 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Peptidase_S64 PF08192.11 EWM21438.1 - 7.7 4.9 15.0 11 4.4 15.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 Macoilin PF09726.9 EWM21438.1 - 7.7 4.9 11.3 13 4.2 11.3 1.3 1 0 0 1 1 1 0 Macoilin family Autophagy_act_C PF03987.15 EWM21439.1 - 0.00061 20.3 0.0 0.00096 19.7 0.0 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain NUDIX PF00293.28 EWM21440.1 - 2.6e-14 53.4 0.0 3.7e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.28 EWM21441.1 - 2.6e-14 53.4 0.0 3.7e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Voltage_CLC PF00654.20 EWM21442.1 - 3.6e-88 296.2 21.2 3.6e-88 296.2 21.2 2.0 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EWM21442.1 - 2.3e-11 43.9 0.4 0.00036 20.9 0.2 2.6 2 0 0 2 2 2 2 CBS domain TAT_signal PF10518.9 EWM21442.1 - 0.0061 16.4 1.2 0.0061 16.4 1.2 3.1 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence DUF2530 PF10745.9 EWM21442.1 - 8.9 6.6 7.7 1.5 9.1 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Aminotran_1_2 PF00155.21 EWM21443.1 - 1.6e-50 172.3 0.0 2.2e-50 171.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EWM21443.1 - 0.0053 15.3 0.0 0.0086 14.6 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EWM21443.1 - 0.048 13.0 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EWM21443.1 - 0.054 12.4 0.0 0.081 11.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Aminotran_MocR PF12897.7 EWM21443.1 - 0.17 10.7 0.0 0.4 9.4 0.0 1.6 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase zf-SNAP50_C PF12251.8 EWM21445.1 - 1.1e-37 129.6 0.0 1.5e-37 129.2 0.0 1.2 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal C1_1 PF00130.22 EWM21445.1 - 0.4 10.6 3.0 1.1 9.2 3.0 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) WD40 PF00400.32 EWM21446.1 - 1.1e-08 35.6 2.3 0.015 16.1 0.0 4.6 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM21446.1 - 1.5e-05 25.2 0.0 0.068 13.5 0.0 2.9 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Erf4 PF10256.9 EWM21448.1 - 9.9e-06 25.7 0.0 1.3e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family WD40 PF00400.32 EWM21449.1 - 1.5e-21 76.3 5.2 1.4e-08 35.2 0.2 6.3 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM21449.1 - 4.4e-06 26.9 0.1 0.74 10.2 0.1 4.7 2 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EWM21449.1 - 0.0092 14.7 0.0 1.3 7.6 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 PQQ PF01011.21 EWM21449.1 - 0.014 15.3 0.0 0.19 11.7 0.0 2.6 2 0 0 2 2 2 0 PQQ enzyme repeat Acetyltransf_1 PF00583.25 EWM21450.1 - 5.2e-11 42.8 0.0 8.2e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EWM21450.1 - 8.2e-06 25.8 0.0 1.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EWM21450.1 - 9.1e-05 22.4 0.0 0.00027 20.8 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.7 EWM21450.1 - 0.00076 19.9 0.0 0.0013 19.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain YL1 PF05764.13 EWM21452.1 - 0.85 9.7 6.3 1.1 9.3 6.3 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Defensin_big PF14862.6 EWM21453.1 - 0.093 13.1 0.5 1.2 9.5 0.0 2.3 2 0 0 2 2 2 0 Big defensin DUF4231 PF14015.6 EWM21453.1 - 0.56 10.7 6.7 2.5 8.6 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) OppC_N PF12911.7 EWM21453.1 - 0.84 9.7 0.1 0.84 9.7 0.1 3.1 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C zf-LITAF-like PF10601.9 EWM21453.1 - 1.4 9.3 3.4 26 5.2 0.0 3.0 3 1 1 4 4 4 0 LITAF-like zinc ribbon domain MARVEL PF01284.23 EWM21453.1 - 1.6 8.7 17.4 0.52 10.3 3.1 2.5 1 1 1 2 2 2 0 Membrane-associating domain DUF21 PF01595.20 EWM21453.1 - 1.8 8.3 13.4 0.065 12.9 5.2 2.0 1 1 1 2 2 2 0 Cyclin M transmembrane N-terminal domain SLATT_5 PF18160.1 EWM21453.1 - 3.5 6.9 6.7 1.1 8.5 1.3 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Abhydrolase_9_N PF15420.6 EWM21453.1 - 4.1 7.3 7.1 2.9 7.8 2.0 2.1 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus Wzy_C_2 PF11846.8 EWM21453.1 - 6.8 6.6 8.0 15 5.5 1.3 2.2 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal DUF202 PF02656.15 EWM21453.1 - 6.9 7.2 14.0 4.6 7.8 2.7 3.0 1 1 0 3 3 3 0 Domain of unknown function (DUF202) Ras PF00071.22 EWM21454.1 - 1.1e-57 194.1 0.0 1.3e-57 193.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EWM21454.1 - 2.4e-32 111.7 0.0 3.3e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EWM21454.1 - 3.8e-12 46.0 0.0 5.2e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EWM21454.1 - 0.00069 19.7 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EWM21454.1 - 0.0027 17.1 0.0 0.0031 16.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EWM21454.1 - 0.018 14.6 0.0 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EWM21454.1 - 0.18 11.8 0.0 0.28 11.2 0.0 1.4 1 1 0 1 1 1 0 Dynamin family SOUL PF04832.12 EWM21456.1 - 8.5e-21 74.8 0.4 1.2e-20 74.4 0.4 1.2 1 0 0 1 1 1 1 SOUL heme-binding protein DUF2358 PF10184.9 EWM21456.1 - 2.1e-16 60.2 0.0 4.2e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.7 EWM21456.1 - 0.012 16.2 0.1 0.031 14.9 0.0 1.7 2 0 0 2 2 2 0 SnoaL-like domain FHA PF00498.26 EWM21457.1 - 2.2e-12 47.2 0.0 3.3e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EWM21457.1 - 8.2e-09 35.7 0.0 1.2e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain polyprenyl_synt PF00348.17 EWM21458.1 - 4.2e-88 294.7 0.0 5.1e-88 294.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase MCM PF00493.23 EWM21459.1 - 1.4e-94 315.4 0.0 2.5e-94 314.6 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EWM21459.1 - 3.7e-36 123.8 0.2 6.5e-36 123.0 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EWM21459.1 - 5.9e-27 93.9 0.6 1.7e-26 92.5 0.2 2.0 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 EWM21459.1 - 3.5e-14 53.2 0.5 4.3e-13 49.8 0.0 2.7 2 0 0 2 2 2 1 MCM N-terminal domain MCM2_N PF12619.8 EWM21459.1 - 1.6e-10 41.5 25.8 1.6e-10 41.5 25.8 2.8 2 1 1 3 3 3 1 Mini-chromosome maintenance protein 2 Mg_chelatase PF01078.21 EWM21459.1 - 4.9e-09 35.9 0.0 1.6e-06 27.6 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EWM21459.1 - 1.9e-06 27.9 0.0 5.6e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EWM21459.1 - 0.011 15.5 0.0 0.15 11.8 0.0 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.11 EWM21459.1 - 0.021 14.7 0.0 0.075 12.9 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 EWM21459.1 - 0.036 13.9 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA lid domain RTT107_BRCT_5 PF16770.5 EWM21460.1 - 0.0033 17.3 0.0 0.0072 16.2 0.0 1.5 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 EWM21460.1 - 0.13 12.6 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Ribosomal_S17_N PF16205.5 EWM21461.1 - 1.7e-29 102.0 0.5 2.9e-29 101.3 0.5 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 EWM21461.1 - 1.5e-26 92.3 0.1 3.1e-26 91.3 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S17 GDPD PF03009.17 EWM21462.1 - 3.9e-08 33.3 0.0 0.0033 17.2 0.0 2.1 1 1 1 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family Novirhabdo_Nv PF05554.11 EWM21462.1 - 0.044 13.5 0.0 0.26 11.0 0.0 1.8 1 1 1 2 2 2 0 Viral hemorrhagic septicemia virus non-virion protein DUF4708 PF15813.5 EWM21463.1 - 0.0028 16.8 0.0 0.0048 16.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4708) F-box-like PF12937.7 EWM21465.1 - 0.00073 19.4 0.8 0.002 18.0 0.8 1.7 1 0 0 1 1 1 1 F-box-like LSM PF01423.22 EWM21466.1 - 1.9e-11 43.5 0.0 2.2e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain Mito_carr PF00153.27 EWM21467.1 - 5e-65 215.5 1.5 3.3e-21 75.0 0.1 3.3 2 1 1 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 EWM21467.1 - 0.0099 16.1 0.0 4.7 7.5 0.0 3.2 3 0 0 3 3 3 2 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase YqgC PF17430.2 EWM21467.1 - 0.12 12.5 0.3 0.46 10.6 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized YqgC-like Hyr1 PF15789.5 EWM21467.1 - 3.2 7.4 4.2 29 4.3 0.1 2.7 2 1 0 2 2 2 0 Hyphally regulated cell wall GPI-anchored protein 1 E1_DerP2_DerF2 PF02221.15 EWM21469.1 - 2.5e-10 40.9 0.1 3.8e-10 40.3 0.1 1.2 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 EWM21469.1 - 0.029 14.7 0.1 0.061 13.7 0.1 1.6 1 1 0 1 1 1 0 ML-like domain UQ_con PF00179.26 EWM21470.1 - 2e-47 160.4 0.0 2.2e-47 160.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EWM21470.1 - 0.028 14.1 0.0 0.038 13.7 0.0 1.3 1 1 0 1 1 1 0 Prokaryotic E2 family B DHHC PF01529.20 EWM21471.1 - 7.9e-22 77.8 4.1 7.9e-22 77.8 4.1 2.2 2 1 0 2 2 2 1 DHHC palmitoyltransferase MRAP PF15183.6 EWM21471.1 - 0.085 12.8 0.4 0.085 12.8 0.4 1.7 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family IGFBP PF00219.18 EWM21471.1 - 0.17 12.5 5.9 0.53 11.0 5.9 1.8 1 0 0 1 1 1 0 Insulin-like growth factor binding protein GMC_oxred_N PF00732.19 EWM21472.1 - 5.9e-39 134.2 8.2 1.6e-38 132.8 6.0 2.4 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EWM21472.1 - 1e-18 68.2 0.1 2.1e-18 67.2 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EWM21472.1 - 1.4e-06 27.7 6.0 2.5e-06 26.9 4.4 2.0 2 1 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 EWM21472.1 - 0.00079 18.8 2.2 0.0012 18.2 1.7 1.5 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 EWM21472.1 - 0.0026 17.0 1.1 0.0026 17.0 1.1 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 EWM21472.1 - 0.0029 16.9 0.5 0.0046 16.2 0.5 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EWM21472.1 - 0.0035 17.6 3.6 0.013 15.7 2.6 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EWM21472.1 - 0.071 11.8 1.1 0.1 11.2 1.1 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 EWM21472.1 - 0.95 8.7 6.0 1.7 7.9 6.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Hydrolase_4 PF12146.8 EWM21473.1 - 7.3e-11 41.8 0.0 1.4e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EWM21473.1 - 1.9e-10 40.9 0.0 3.3e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cutinase PF01083.22 EWM21473.1 - 0.064 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Cutinase VirJ PF06057.11 EWM21473.1 - 0.075 12.9 0.0 0.83 9.5 0.0 2.2 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) FUSC PF04632.12 EWM21474.1 - 0.0019 16.8 14.3 0.0024 16.5 14.3 1.1 1 0 0 1 1 1 1 Fusaric acid resistance protein family Atg14 PF10186.9 EWM21474.1 - 0.05 12.7 10.4 0.074 12.1 10.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cnn_1N PF07989.11 EWM21474.1 - 0.086 13.0 3.6 0.33 11.1 0.0 2.8 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 SLD3 PF08639.10 EWM21474.1 - 0.19 10.4 7.2 0.37 9.5 7.2 1.5 1 1 0 1 1 1 0 DNA replication regulator SLD3 FlaC_arch PF05377.11 EWM21474.1 - 0.28 11.6 1.1 4.3 7.8 0.1 2.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) YabA PF06156.13 EWM21474.1 - 0.39 11.4 12.0 0.13 13.0 8.6 2.0 2 0 0 2 2 2 0 Initiation control protein YabA UPF0242 PF06785.11 EWM21474.1 - 1.1 9.3 12.8 2.4 8.2 12.8 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF724 PF05266.14 EWM21474.1 - 1.2 8.9 9.5 2.6 7.8 9.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ALMT PF11744.8 EWM21474.1 - 1.4 7.6 5.6 1.9 7.2 5.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter V_ATPase_I PF01496.19 EWM21474.1 - 1.8 6.4 6.6 3 5.7 6.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LCD1 PF09798.9 EWM21474.1 - 2 6.8 4.3 2.4 6.6 4.3 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Macoilin PF09726.9 EWM21474.1 - 3.7 6.0 11.9 6.8 5.1 10.4 1.7 1 1 1 2 2 2 0 Macoilin family ADIP PF11559.8 EWM21474.1 - 7.2 6.7 18.3 1.6 8.8 5.0 1.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF641 PF04859.12 EWM21474.1 - 8 6.8 12.8 0.32 11.3 4.0 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) BSP_II PF05432.11 EWM21476.1 - 0.0011 18.8 17.7 0.0011 18.8 17.7 1.7 2 0 0 2 2 2 1 Bone sialoprotein II (BSP-II) PRCC PF10253.9 EWM21476.1 - 0.041 14.7 37.0 0.012 16.4 27.8 3.4 1 1 1 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Rhomboid_SP PF12595.8 EWM21476.1 - 0.078 12.3 2.7 0.057 12.8 0.4 1.9 2 0 0 2 2 2 0 Rhomboid serine protease THOC2_N PF16134.5 EWM21476.1 - 2.7 6.5 16.5 0.43 9.1 8.9 2.1 2 0 0 2 2 2 0 THO complex subunit 2 N-terminus Myosin_head PF00063.21 EWM21477.1 - 4.7e-196 653.0 0.0 7.7e-196 652.3 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.6 EWM21477.1 - 0.0019 18.5 1.8 0.0079 16.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain ATPase PF06745.13 EWM21477.1 - 0.028 13.8 0.1 0.028 13.8 0.1 2.0 2 0 0 2 2 2 0 KaiC AAA_16 PF13191.6 EWM21477.1 - 0.1 13.0 0.0 0.1 13.0 0.0 3.4 2 1 0 2 2 2 0 AAA ATPase domain DUF1664 PF07889.12 EWM21477.1 - 1.9 8.5 16.4 0.8 9.8 3.2 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) DUF998 PF06197.13 EWM21479.1 - 0.0045 16.6 2.5 0.0064 16.1 0.9 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF998) DUF4079 PF13301.6 EWM21479.1 - 0.019 15.1 5.5 0.033 14.3 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) Cytochrom_B561 PF03188.16 EWM21479.1 - 0.068 13.3 11.9 0.038 14.1 7.7 2.5 2 1 0 2 2 2 0 Eukaryotic cytochrome b561 HGTP_anticodon PF03129.20 EWM21480.1 - 5.9e-18 64.8 0.0 1.6e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EWM21480.1 - 4.8e-08 33.2 0.0 1.6e-07 31.5 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS PF00458.20 EWM21480.1 - 8e-07 29.1 2.9 2.5e-06 27.5 2.9 1.9 1 0 0 1 1 1 1 WHEP-TRS domain Peptidase_S8 PF00082.22 EWM21481.1 - 2.8e-42 145.0 0.0 3.2e-35 121.8 0.0 2.2 2 0 0 2 2 2 2 Subtilase family CagY_M PF07337.11 EWM21481.1 - 0.47 10.1 3.8 0.13 11.9 0.2 2.0 2 0 0 2 2 2 0 DC-EC Repeat Notch PF00066.17 EWM21481.1 - 1.4 9.4 7.8 5 7.7 7.8 2.1 1 0 0 1 1 1 0 LNR domain Pkinase PF00069.25 EWM21482.1 - 2.8e-68 230.1 0.0 4.6e-68 229.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM21482.1 - 4.7e-31 108.0 0.0 6.8e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 EWM21482.1 - 2.8e-22 76.5 0.1 2.9e-09 35.8 0.1 4.5 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 EWM21482.1 - 8.5e-21 74.2 0.8 4.5e-13 49.5 0.2 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EWM21482.1 - 1.5e-16 58.9 0.0 2.4e-05 23.9 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 EWM21482.1 - 4.4e-16 58.5 0.1 1.6e-07 31.0 0.2 3.8 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EWM21482.1 - 5.5e-15 54.1 1.3 1.4e-06 27.5 0.1 4.3 4 0 0 4 4 4 3 EF hand Kdo PF06293.14 EWM21482.1 - 1.1e-07 31.4 2.2 2.5e-07 30.3 2.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SPARC_Ca_bdg PF10591.9 EWM21482.1 - 0.00058 20.1 0.1 0.016 15.6 0.0 2.6 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Haspin_kinase PF12330.8 EWM21482.1 - 0.0049 15.9 0.6 0.0049 15.9 0.6 1.6 2 0 0 2 2 2 1 Haspin like kinase domain EF-hand_9 PF14658.6 EWM21482.1 - 0.0062 16.8 0.0 0.66 10.3 0.0 3.1 3 0 0 3 3 2 1 EF-hand domain EF-hand_4 PF12763.7 EWM21482.1 - 0.0063 16.5 0.1 0.46 10.5 0.0 2.5 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand APH PF01636.23 EWM21482.1 - 0.011 15.7 0.4 1.6 8.6 0.0 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EWM21482.1 - 0.023 14.0 0.0 0.068 12.5 0.0 1.9 1 1 1 2 2 2 0 Kinase-like DED PF01335.21 EWM21482.1 - 0.026 14.8 1.0 0.53 10.6 0.1 3.1 3 0 0 3 3 3 0 Death effector domain EF-hand_11 PF08976.11 EWM21482.1 - 0.076 13.9 0.0 0.29 12.0 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain Pkinase PF00069.25 EWM21483.1 - 1.3e-64 218.2 0.0 1.9e-64 217.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM21483.1 - 3.9e-30 105.0 0.0 5.8e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 EWM21483.1 - 1.6e-22 77.3 0.1 2.5e-09 36.0 0.1 4.5 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 EWM21483.1 - 5.7e-21 74.7 0.9 3.8e-13 49.7 0.2 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EWM21483.1 - 8.7e-17 59.6 0.0 2e-05 24.1 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 EWM21483.1 - 2.8e-16 59.1 0.1 1.4e-07 31.2 0.2 3.8 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EWM21483.1 - 3.3e-15 54.8 1.3 1.2e-06 27.7 0.1 4.4 4 0 0 4 4 4 3 EF hand Kdo PF06293.14 EWM21483.1 - 2.1e-07 30.5 2.5 4.5e-07 29.4 2.5 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SPARC_Ca_bdg PF10591.9 EWM21483.1 - 0.00047 20.5 0.1 0.015 15.6 0.0 2.6 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 EWM21483.1 - 0.0046 17.2 0.0 0.56 10.6 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_4 PF12763.7 EWM21483.1 - 0.0048 16.8 0.1 0.4 10.7 0.0 2.4 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Haspin_kinase PF12330.8 EWM21483.1 - 0.0066 15.4 0.9 0.0066 15.4 0.9 1.6 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 EWM21483.1 - 0.0082 16.1 0.4 1.4 8.8 0.0 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EWM21483.1 - 0.025 13.9 0.0 0.07 12.4 0.0 1.7 1 1 0 1 1 1 0 Kinase-like DED PF01335.21 EWM21483.1 - 0.03 14.6 1.6 0.45 10.9 0.1 3.1 3 0 0 3 3 3 0 Death effector domain EF-hand_11 PF08976.11 EWM21483.1 - 0.064 14.1 0.0 0.24 12.3 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain GTP_EFTU PF00009.27 EWM21485.1 - 2e-54 184.1 0.0 2.9e-54 183.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EWM21485.1 - 3.2e-41 140.2 0.1 7.3e-41 139.0 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EWM21485.1 - 3.8e-15 56.0 0.9 8.6e-15 54.9 0.9 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EWM21485.1 - 5.7e-06 26.4 0.0 0.0013 18.8 0.0 2.5 2 1 0 2 2 2 2 50S ribosome-binding GTPase FlpD PF02662.16 EWM21485.1 - 0.0025 17.8 0.1 0.018 15.0 0.0 2.1 2 0 0 2 2 2 1 Methyl-viologen-reducing hydrogenase, delta subunit GTP_EFTU_D4 PF14578.6 EWM21485.1 - 0.011 15.6 0.4 0.035 14.0 0.4 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 4 Semialdhyde_dhC PF02774.18 EWM21485.1 - 0.032 14.3 0.5 0.068 13.2 0.1 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain Gtr1_RagA PF04670.12 EWM21485.1 - 0.093 12.1 0.0 0.29 10.5 0.0 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Abhydrolase_3 PF07859.13 EWM21486.1 - 1e-57 195.4 0.2 1.4e-57 195.0 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EWM21486.1 - 9.7e-08 31.3 0.8 2.9e-07 29.7 0.8 1.6 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 EWM21486.1 - 1.2e-06 27.7 0.0 1.7e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 EWM21486.1 - 8.3e-05 22.2 0.1 0.027 13.9 0.2 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 EWM21486.1 - 8.8e-05 21.5 0.0 0.00013 20.9 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme BAAT_C PF08840.11 EWM21486.1 - 0.069 13.1 0.0 1.1 9.2 0.0 2.3 3 0 0 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 EWM21486.1 - 0.15 11.3 0.0 8.1 5.6 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DLH PF01738.18 EWM21486.1 - 0.2 11.2 0.0 0.78 9.2 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF4795 PF16043.5 EWM21487.1 - 0.00021 21.0 5.0 0.0013 18.4 1.1 2.9 1 1 0 2 2 2 1 Domain of unknown function (DUF4795) PSD2 PF07624.11 EWM21487.1 - 0.13 12.0 0.3 0.46 10.3 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1585) P22_AR_C PF10548.9 EWM21487.1 - 0.16 12.1 0.4 0.87 9.8 0.0 2.3 2 0 0 2 2 2 0 P22AR C-terminal domain DUF4873 PF16170.5 EWM21487.1 - 0.17 12.1 1.0 0.57 10.4 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4873) CDO_I PF05995.12 EWM21487.1 - 0.34 10.2 3.3 3.7 6.8 0.1 2.9 3 0 0 3 3 3 0 Cysteine dioxygenase type I RRM_1 PF00076.22 EWM21490.1 - 0.0035 17.1 0.0 0.0096 15.7 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Histone PF00125.24 EWM21492.1 - 1.5e-18 67.4 0.0 1.8e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EWM21492.1 - 2.1e-12 46.5 0.6 3.7e-12 45.7 0.6 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EWM21492.1 - 0.00057 20.1 0.0 0.00078 19.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DHHC PF01529.20 EWM21494.1 - 3.8e-26 91.8 13.2 3.8e-26 91.8 13.2 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase FAM131 PF15010.6 EWM21494.1 - 0.0072 16.3 0.6 0.012 15.5 0.6 1.3 1 0 0 1 1 1 1 Putative cell signalling Suv3_C_1 PF18147.1 EWM21495.1 - 2.6e-17 62.4 0.1 5.5e-17 61.4 0.1 1.6 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 SUV3_C PF12513.8 EWM21495.1 - 9.9e-16 57.4 0.6 2.3e-15 56.2 0.2 1.9 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 EWM21495.1 - 3.6e-09 37.0 0.0 6.6e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Band_7 PF01145.25 EWM21496.1 - 9.9e-24 84.3 0.6 1.3e-23 83.9 0.6 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 EWM21496.1 - 0.013 15.2 0.2 0.021 14.5 0.2 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family RNase_P_Rpp14 PF01900.19 EWM21496.1 - 0.041 14.1 0.0 0.1 12.8 0.0 1.9 1 1 0 1 1 1 0 Rpp14/Pop5 family Nuc_sug_transp PF04142.15 EWM21497.1 - 5.2e-108 360.9 16.3 6.2e-108 360.7 16.3 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 EWM21497.1 - 3.3e-07 30.6 5.7 3.3e-07 30.6 5.7 2.5 2 1 0 2 2 2 1 EamA-like transporter family UAA PF08449.11 EWM21497.1 - 1.2e-05 24.7 11.1 0.00017 21.0 11.1 2.2 1 1 0 1 1 1 1 UAA transporter family CRT-like PF08627.10 EWM21497.1 - 0.0012 17.8 2.2 0.0012 17.8 2.2 2.2 3 0 0 3 3 3 1 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 EWM21497.1 - 0.0064 15.9 4.2 0.0064 15.9 4.2 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family SAPS PF04499.15 EWM21498.1 - 9.7e-13 47.7 0.6 5.5e-07 28.7 0.0 4.2 4 1 1 5 5 5 3 SIT4 phosphatase-associated protein RTC PF01137.21 EWM21499.1 - 7.9e-37 126.6 0.5 4.7e-22 78.3 1.0 3.2 3 0 0 3 3 3 3 RNA 3'-terminal phosphate cyclase 2_5_RNA_ligase2 PF13563.6 EWM21499.1 - 4.9e-29 101.2 0.1 8.4e-29 100.4 0.1 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily DNA_repr_REX1B PF14966.6 EWM21500.1 - 2.3e-24 85.9 0.8 5e-24 84.8 0.8 1.6 1 0 0 1 1 1 1 DNA repair REX1-B NRIP1_repr_3 PF15689.5 EWM21500.1 - 0.055 13.8 1.2 0.15 12.4 0.2 2.1 2 0 0 2 2 2 0 Nuclear receptor-interacting protein 1 repression 3 Arg_decarb_HB PF17810.1 EWM21500.1 - 0.1 12.9 1.8 0.21 11.9 0.2 2.3 3 0 0 3 3 3 0 Arginine decarboxylase helical bundle domain ABC_tran PF00005.27 EWM21501.1 - 7e-14 52.5 0.1 7.5e-13 49.2 0.1 2.4 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EWM21501.1 - 3.3e-12 46.8 2.3 4e-06 26.8 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EWM21501.1 - 0.00051 19.7 0.1 0.00099 18.8 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EWM21501.1 - 0.0083 15.6 0.1 4.5 6.6 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EWM21501.1 - 0.022 14.6 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 EWM21501.1 - 0.036 13.6 0.0 0.094 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EWM21501.1 - 0.051 14.0 0.4 0.1 12.9 0.4 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 EWM21501.1 - 0.066 13.7 0.5 0.12 12.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EWM21501.1 - 0.084 13.1 0.1 0.19 12.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EWM21501.1 - 0.088 12.7 0.4 1.8 8.5 0.1 2.3 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 EWM21501.1 - 0.11 12.8 1.0 0.23 11.8 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 EWM21501.1 - 0.11 12.2 0.2 0.19 11.4 0.2 1.3 1 0 0 1 1 1 0 AAA ATPase domain Arf PF00025.21 EWM21501.1 - 0.17 11.4 0.1 0.29 10.6 0.1 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family DUF3584 PF12128.8 EWM21501.1 - 0.19 9.2 0.0 0.29 8.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_24 PF13479.6 EWM21501.1 - 0.21 11.3 0.0 0.39 10.4 0.0 1.5 2 0 0 2 2 2 0 AAA domain tRNA_SAD PF07973.14 EWM21502.1 - 2.6e-08 33.8 0.9 5.9e-08 32.7 0.9 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 EWM21502.1 - 3.7e-06 25.7 0.0 4.7e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) FmiP_Thoc5 PF09766.9 EWM21504.1 - 0.002 17.5 1.7 0.002 17.5 1.7 1.5 1 1 0 1 1 1 1 Fms-interacting protein/Thoc5 DUF1664 PF07889.12 EWM21504.1 - 0.0028 17.7 4.7 0.81 9.7 1.7 2.9 1 1 0 2 2 2 1 Protein of unknown function (DUF1664) APG17 PF04108.12 EWM21504.1 - 0.0076 15.4 2.5 0.035 13.2 0.4 2.1 1 1 1 2 2 2 1 Autophagy protein Apg17 Snapin_Pallidin PF14712.6 EWM21504.1 - 0.011 16.2 4.4 0.014 15.8 0.5 2.7 3 1 0 3 3 3 0 Snapin/Pallidin Phage_GP20 PF06810.11 EWM21504.1 - 0.038 13.8 4.6 2 8.2 0.4 2.6 1 1 0 2 2 2 0 Phage minor structural protein GP20 Plant_vir_prot PF01307.17 EWM21504.1 - 0.05 13.8 0.0 0.081 13.2 0.0 1.3 1 0 0 1 1 1 0 Plant viral movement protein EzrA PF06160.12 EWM21504.1 - 0.052 11.7 3.1 0.065 11.4 0.4 1.9 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA TMPIT PF07851.13 EWM21504.1 - 0.058 12.6 4.8 0.045 13.0 1.3 2.0 1 1 1 2 2 2 0 TMPIT-like protein RmuC PF02646.16 EWM21504.1 - 0.061 12.4 3.5 0.24 10.5 0.4 2.4 1 1 1 2 2 2 0 RmuC family Sec20 PF03908.13 EWM21504.1 - 0.078 12.9 0.3 0.48 10.4 0.0 2.2 2 1 0 2 2 2 0 Sec20 Fib_alpha PF08702.10 EWM21504.1 - 0.097 12.9 4.3 4.2 7.6 0.2 2.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family COG5 PF10392.9 EWM21504.1 - 0.11 12.6 3.6 0.31 11.2 0.3 2.7 2 1 1 3 3 3 0 Golgi transport complex subunit 5 DUF745 PF05335.13 EWM21504.1 - 0.15 11.8 4.6 2.6 7.7 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Mt_ATP-synt_B PF05405.14 EWM21504.1 - 0.15 11.7 2.2 6 6.5 0.1 2.4 1 1 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) BST2 PF16716.5 EWM21504.1 - 0.21 12.2 7.2 0.43 11.2 0.3 3.0 1 1 1 3 3 3 0 Bone marrow stromal antigen 2 Flp1_like PF16982.5 EWM21504.1 - 0.24 10.8 1.3 0.54 9.7 1.3 1.5 1 0 0 1 1 1 0 Putative Flagellin, Flp1-like, domain HisKA_3 PF07730.13 EWM21504.1 - 0.28 11.7 10.9 2 9.0 0.3 4.6 1 1 3 4 4 4 0 Histidine kinase V-SNARE PF05008.15 EWM21504.1 - 0.33 11.4 8.3 0.18 12.2 2.0 3.0 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DHR10 PF18595.1 EWM21504.1 - 0.41 10.7 14.6 0.4 10.8 3.9 2.9 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain HemX PF04375.14 EWM21504.1 - 0.43 9.8 6.8 0.24 10.6 2.0 2.1 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase T3SSipB PF16535.5 EWM21504.1 - 0.45 11.0 3.1 14 6.1 3.1 2.3 1 1 0 1 1 1 0 Type III cell invasion protein SipB Spc7 PF08317.11 EWM21504.1 - 0.6 8.9 10.2 0.8 8.5 8.2 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein Swi5 PF07061.11 EWM21504.1 - 0.81 9.8 4.2 21 5.3 0.6 3.0 3 1 0 3 3 3 0 Swi5 KxDL PF10241.9 EWM21504.1 - 0.93 9.8 3.8 2.1 8.7 0.8 2.7 2 1 1 3 3 3 0 Uncharacterized conserved protein Syntaxin-6_N PF09177.11 EWM21504.1 - 1 10.0 6.6 14 6.3 2.8 3.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF2205 PF10224.9 EWM21504.1 - 1.1 9.3 8.0 9.9 6.2 0.2 3.5 3 1 1 4 4 4 0 Short coiled-coil protein ATG16 PF08614.11 EWM21504.1 - 1.8 8.8 13.6 3.9 7.6 10.5 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CorA PF01544.18 EWM21504.1 - 2.1 7.6 5.7 3.2 7.0 2.5 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF16 PF01519.16 EWM21504.1 - 2.9 8.5 5.7 1.1e+02 3.4 5.7 2.8 1 1 0 1 1 1 0 Protein of unknown function DUF16 DLP_helical PF18709.1 EWM21504.1 - 4.1 6.5 6.5 2.9 7.0 0.7 2.3 1 1 0 1 1 1 0 Dynamin-like helical domain TPR_MLP1_2 PF07926.12 EWM21504.1 - 8.3 6.5 10.2 19 5.3 2.6 2.8 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Hrs_helical PF12210.8 EWM21504.1 - 8.4 7.0 9.2 23 5.6 0.4 3.3 2 2 1 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Condensin2nSMC PF12422.8 EWM21506.1 - 1.3e-53 181.2 0.0 3.1e-53 180.0 0.0 1.7 1 0 0 1 1 1 1 Condensin II non structural maintenance of chromosomes subunit HEAT PF02985.22 EWM21506.1 - 1.7e-05 24.7 5.1 0.6 10.5 0.1 5.4 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 EWM21506.1 - 0.00095 19.5 8.8 0.016 15.6 0.2 4.2 4 0 0 4 4 4 2 HEAT repeats Cnd1 PF12717.7 EWM21506.1 - 0.0055 16.8 0.1 0.29 11.2 0.0 3.0 1 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EWM21506.1 - 0.038 14.5 0.6 0.038 14.5 0.6 4.1 3 0 0 3 3 3 0 HEAT-like repeat Adaptin_N PF01602.20 EWM21506.1 - 0.13 10.8 0.1 0.23 10.0 0.1 1.3 1 0 0 1 1 1 0 Adaptin N terminal region HSF_DNA-bind PF00447.17 EWM21507.1 - 1.5e-23 83.2 0.5 3e-23 82.3 0.2 1.7 2 0 0 2 2 2 1 HSF-type DNA-binding Pribosyltran PF00156.27 EWM21508.1 - 8.7e-11 41.6 0.0 1.6e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyltran_N PF13793.6 EWM21508.1 - 0.00043 20.2 0.0 0.0037 17.2 0.0 2.4 3 0 0 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EWM21508.1 - 0.021 14.9 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain OGFr_N PF04664.13 EWM21508.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Opioid growth factor receptor (OGFr) conserved region PknH_C PF14032.6 EWM21508.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 PknH-like extracellular domain FAD_binding_1 PF00667.20 EWM21508.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Peptidase_A22B PF04258.13 EWM21510.1 - 1.2e-87 294.1 2.0 1.7e-87 293.6 2.0 1.2 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 EWM21510.1 - 1.3e-06 28.1 0.9 1.3e-06 28.1 0.9 2.5 3 0 0 3 3 3 1 Signal-peptide peptidase, presenilin aspartyl protease Presenilin PF01080.17 EWM21510.1 - 0.063 12.0 1.6 0.1 11.4 0.9 1.7 2 0 0 2 2 2 0 Presenilin MAM33 PF02330.16 EWM21511.1 - 1.2e-22 80.9 8.6 1.6e-22 80.5 8.6 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein AAA PF00004.29 EWM21512.1 - 2e-52 177.1 0.0 3.2e-39 134.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EWM21512.1 - 1.9e-09 37.2 0.1 7.1e-09 35.3 0.1 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EWM21512.1 - 7.2e-09 36.2 0.4 0.01 16.2 0.0 4.0 3 1 0 4 4 4 2 AAA ATPase domain TIP49 PF06068.13 EWM21512.1 - 1.1e-06 28.1 0.0 0.0096 15.2 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 EWM21512.1 - 1.4e-06 28.6 0.7 0.03 14.6 0.2 3.9 2 2 1 3 3 3 1 AAA domain AAA_2 PF07724.14 EWM21512.1 - 3.2e-06 27.4 0.0 4.7e-05 23.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 EWM21512.1 - 5.2e-05 22.7 0.8 0.0036 16.7 0.1 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 EWM21512.1 - 8.1e-05 22.4 0.0 0.13 12.0 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 EWM21512.1 - 0.00012 21.9 0.0 0.12 12.2 0.0 2.8 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EWM21512.1 - 0.00025 21.1 0.2 0.014 15.4 0.1 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EWM21512.1 - 0.00028 20.7 0.2 0.7 9.6 0.0 2.8 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_28 PF13521.6 EWM21512.1 - 0.00031 21.0 0.1 0.61 10.3 0.0 2.8 3 0 0 3 3 3 2 AAA domain CDC48_2 PF02933.17 EWM21512.1 - 0.00042 20.0 0.3 0.004 16.9 0.0 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_33 PF13671.6 EWM21512.1 - 0.002 18.3 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EWM21512.1 - 0.0062 16.3 0.0 0.36 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 EWM21512.1 - 0.0075 15.7 0.0 13 5.1 0.0 3.7 4 0 0 4 4 4 0 Bacterial TniB protein Sigma54_activat PF00158.26 EWM21512.1 - 0.011 15.5 0.0 5.1 6.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain CPT PF07931.12 EWM21512.1 - 0.019 14.8 0.0 0.2 11.5 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein RNA_helicase PF00910.22 EWM21512.1 - 0.02 15.3 0.0 0.25 11.7 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 EWM21512.1 - 0.021 14.3 0.0 0.85 9.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 EWM21512.1 - 0.023 15.2 0.1 0.078 13.5 0.1 1.9 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 EWM21512.1 - 0.023 15.2 0.0 4.1 8.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EWM21512.1 - 0.031 14.3 0.0 3.4 7.7 0.0 3.0 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 EWM21512.1 - 0.035 14.0 0.0 0.14 12.1 0.0 2.0 3 0 0 3 3 1 0 Rad17 P-loop domain ATPase PF06745.13 EWM21512.1 - 0.048 13.0 0.2 0.62 9.4 0.1 2.4 2 0 0 2 2 2 0 KaiC ATPase_2 PF01637.18 EWM21512.1 - 0.056 13.4 0.5 8.5 6.2 0.0 3.0 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 EWM21512.1 - 0.074 12.1 0.0 4.7 6.2 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 EWM21512.1 - 0.081 12.5 4.7 17 4.9 0.0 3.8 5 0 0 5 5 3 0 AAA domain AAA_11 PF13086.6 EWM21512.1 - 0.16 11.7 0.0 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EWM21512.1 - 0.17 12.2 0.1 2.1 8.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 EWM21512.1 - 0.18 11.2 0.0 13 5.2 0.0 2.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 SBBP PF06739.11 EWM21515.1 - 2.9e-21 75.2 44.9 0.00043 20.2 0.3 7.5 7 0 0 7 7 7 7 Beta-propeller repeat DUF4346 PF14251.6 EWM21515.1 - 0.0075 16.3 0.0 12 6.0 0.0 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4346) Peptidase_M26_N PF05342.14 EWM21515.1 - 3.5 7.0 4.7 22 4.3 0.1 3.9 4 1 0 4 4 4 0 M26 IgA1-specific Metallo-endopeptidase N-terminal region KH_1 PF00013.29 EWM21516.1 - 1.2e-30 105.1 9.3 2.5e-16 59.3 1.9 2.4 2 0 0 2 2 2 2 KH domain MOEP19 PF16005.5 EWM21516.1 - 1.7e-07 31.1 0.0 0.0041 17.1 0.0 2.4 2 0 0 2 2 2 2 KH-like RNA-binding domain KH_4 PF13083.6 EWM21516.1 - 7.9e-07 28.9 6.1 0.001 18.9 0.1 3.3 3 0 0 3 3 3 2 KH domain KH_2 PF07650.17 EWM21516.1 - 3.5e-05 23.5 0.4 0.027 14.3 0.0 2.5 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 EWM21516.1 - 0.093 12.8 1.7 7.5 6.7 0.2 2.4 2 0 0 2 2 2 0 NusA-like KH domain LAP1C PF05609.12 EWM21516.1 - 9.2 5.2 12.0 13 4.7 12.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SGL PF08450.12 EWM21517.1 - 2.2e-37 129.0 0.0 3.8e-37 128.2 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 EWM21517.1 - 0.0091 16.1 0.0 3.9 7.7 0.0 3.2 3 0 0 3 3 3 1 Strictosidine synthase NHL PF01436.21 EWM21517.1 - 0.013 15.5 1.7 14 5.9 0.1 3.8 3 0 0 3 3 3 0 NHL repeat Arylesterase PF01731.20 EWM21517.1 - 0.13 12.4 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Arylesterase Bombesin PF02044.17 EWM21517.1 - 3 8.1 7.3 12 6.2 0.3 3.2 3 0 0 3 3 3 0 Bombesin-like peptide Esterase_phd PF10503.9 EWM21518.1 - 9.8e-06 25.2 0.0 2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 EWM21518.1 - 1.5e-05 24.9 0.0 9e-05 22.4 0.0 1.9 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 EWM21518.1 - 2.7e-05 24.0 0.1 0.00012 21.8 0.1 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EWM21518.1 - 6.2e-05 23.7 5.8 6.2e-05 23.7 5.8 2.2 1 1 1 2 2 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EWM21518.1 - 9e-05 22.4 0.0 0.00015 21.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EWM21518.1 - 0.00012 21.6 0.0 0.066 12.7 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 EWM21518.1 - 0.00099 18.8 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Putative esterase DUF2974 PF11187.8 EWM21518.1 - 0.0012 18.4 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) DLH PF01738.18 EWM21518.1 - 0.0014 18.2 0.0 0.0032 17.1 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 EWM21518.1 - 0.0017 17.6 0.0 0.049 12.9 0.0 2.2 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 EWM21518.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.7 EWM21518.1 - 0.24 11.2 0.0 0.37 10.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 EWM21518.1 - 0.25 10.2 0.0 0.38 9.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme TIG PF01833.24 EWM21519.1 - 4.6e-26 90.7 2.8 9.8e-09 35.2 0.1 3.8 3 0 0 3 3 3 3 IPT/TIG domain FG-GAP PF01839.23 EWM21519.1 - 4.6e-25 87.4 56.7 1.1e-07 31.8 3.4 6.8 6 0 0 6 6 6 6 FG-GAP repeat FG-GAP_2 PF14312.6 EWM21519.1 - 1.3e-11 44.5 33.8 0.00082 19.6 2.0 5.8 5 0 0 5 5 5 5 FG-GAP repeat TRP PF06011.12 EWM21519.1 - 1e-06 27.8 0.5 2.6e-06 26.5 0.5 1.6 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel VCBS PF13517.6 EWM21519.1 - 3.7e-06 27.4 26.9 0.023 15.3 3.8 5.0 2 2 3 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Ephrin_rec_like PF07699.13 EWM21519.1 - 0.00066 19.4 14.7 0.0018 18.0 8.0 2.6 2 0 0 2 2 2 1 Putative ephrin-receptor like SUIM_assoc PF16619.5 EWM21519.1 - 0.18 11.9 2.3 0.4 10.8 2.3 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 zf-C3HC4_3 PF13920.6 EWM21520.1 - 5.4e-06 26.2 8.1 8.4e-06 25.6 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EWM21520.1 - 9.5e-05 22.2 9.7 0.00017 21.3 9.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EWM21520.1 - 0.042 13.8 9.9 0.08 12.9 9.9 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 EWM21520.1 - 0.17 11.8 6.0 0.49 10.3 6.1 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EWM21520.1 - 3.4 7.8 6.7 8 6.6 6.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger SDA1 PF05285.12 EWM21520.1 - 8.5 5.7 19.7 0.36 10.2 2.6 2.1 2 0 0 2 2 2 0 SDA1 SRP54 PF00448.22 EWM21521.1 - 4.2e-77 258.2 0.1 6.2e-77 257.7 0.1 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EWM21521.1 - 1.3e-28 99.5 5.6 5.6e-28 97.5 0.1 2.8 2 0 0 2 2 2 1 Signal peptide binding domain SRP54_N PF02881.19 EWM21521.1 - 4e-17 62.2 1.5 4e-17 62.2 1.5 2.1 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.6 EWM21521.1 - 3.9e-07 30.3 0.0 9.1e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 EWM21521.1 - 9.5e-07 28.6 0.2 9.5e-06 25.3 0.2 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 EWM21521.1 - 2e-05 24.4 0.2 4.9e-05 23.1 0.2 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EWM21521.1 - 7.8e-05 22.0 0.1 0.00016 21.1 0.1 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 EWM21521.1 - 0.00029 21.3 0.0 0.00062 20.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain MeaB PF03308.16 EWM21521.1 - 0.0014 17.7 0.1 0.015 14.3 0.1 2.2 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 EWM21521.1 - 0.0019 18.3 0.4 0.017 15.2 0.2 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_17 PF13207.6 EWM21521.1 - 0.0035 17.8 0.1 0.013 16.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 EWM21521.1 - 0.0038 16.7 0.6 2.5 7.5 0.2 3.1 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit ResIII PF04851.15 EWM21521.1 - 0.0049 16.9 0.4 0.011 15.8 0.4 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CLP1_P PF16575.5 EWM21521.1 - 0.006 16.4 0.1 1.3 8.8 0.0 2.3 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_19 PF13245.6 EWM21521.1 - 0.0076 16.6 0.0 0.02 15.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EWM21521.1 - 0.013 15.8 0.2 0.062 13.6 0.1 2.2 2 1 0 2 2 2 0 AAA domain CbiA PF01656.23 EWM21521.1 - 0.018 15.1 0.0 0.063 13.3 0.0 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain APS_kinase PF01583.20 EWM21521.1 - 0.021 14.7 0.8 0.046 13.6 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase Fe-ADH PF00465.19 EWM21521.1 - 0.029 13.2 0.0 0.053 12.3 0.0 1.4 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase AAA_7 PF12775.7 EWM21521.1 - 0.033 13.7 0.1 0.064 12.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region MobB PF03205.14 EWM21521.1 - 0.043 13.7 0.0 0.094 12.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.6 EWM21521.1 - 0.044 14.0 0.0 0.093 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EWM21521.1 - 0.064 13.0 0.1 17 5.2 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF373 PF04123.13 EWM21521.1 - 0.099 12.1 0.4 0.15 11.5 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Arf PF00025.21 EWM21521.1 - 0.13 11.7 0.1 0.35 10.3 0.0 1.7 2 0 0 2 2 1 0 ADP-ribosylation factor family NB-ARC PF00931.22 EWM21521.1 - 0.19 10.9 0.8 2.8 7.1 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain FGGY_C PF02782.16 EWM21523.1 - 2e-09 37.5 0.0 3.4e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EWM21523.1 - 0.00022 20.9 0.0 0.072 12.6 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain PsbP PF01789.16 EWM21524.1 - 1e-13 51.7 0.0 1.3e-13 51.4 0.0 1.1 1 0 0 1 1 1 1 PsbP Acetyltransf_7 PF13508.7 EWM21526.1 - 6.2e-06 26.6 0.0 1e-05 25.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EWM21526.1 - 3.1e-05 24.2 0.0 5.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EWM21526.1 - 0.093 12.7 0.0 0.54 10.2 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain MNR PF15718.5 EWM21529.1 - 0.17 10.0 0.4 0.22 9.6 0.4 1.1 1 0 0 1 1 1 0 Protein moonraker DHQ_synthase PF01761.20 EWM21531.1 - 9.6e-05 21.7 0.0 0.0002 20.6 0.0 1.5 1 1 0 1 1 1 1 3-dehydroquinate synthase MPS2 PF17060.5 EWM21533.1 - 1.3e-06 27.9 6.7 1.3e-06 27.9 6.7 3.0 2 1 1 3 3 3 1 Monopolar spindle protein 2 GRIP PF01465.20 EWM21533.1 - 9.9e-05 22.2 0.0 0.00026 20.8 0.0 1.7 1 0 0 1 1 1 1 GRIP domain Exonuc_VII_L PF02601.15 EWM21533.1 - 0.0004 20.0 17.4 0.063 12.8 10.3 2.2 2 0 0 2 2 2 2 Exonuclease VII, large subunit ATG16 PF08614.11 EWM21533.1 - 0.0022 18.3 20.8 0.0022 18.3 20.8 3.2 3 0 0 3 3 3 2 Autophagy protein 16 (ATG16) HAP1_N PF04849.13 EWM21533.1 - 0.0033 16.7 7.8 0.0033 16.7 7.8 2.7 2 1 0 2 2 2 1 HAP1 N-terminal conserved region HBM PF16591.5 EWM21533.1 - 0.0092 15.4 15.3 0.0092 15.4 15.3 2.4 2 0 0 2 2 2 1 Helical bimodular sensor domain SpoIIID PF12116.8 EWM21533.1 - 0.036 14.2 0.9 0.08 13.0 0.8 1.7 1 1 0 1 1 1 0 Stage III sporulation protein D DUF1848 PF08902.11 EWM21533.1 - 0.22 11.2 1.8 0.24 11.1 0.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1848) Laminin_II PF06009.12 EWM21533.1 - 0.43 10.6 10.3 0.23 11.5 6.8 2.2 2 0 0 2 2 2 0 Laminin Domain II TMF_DNA_bd PF12329.8 EWM21533.1 - 0.52 10.3 41.6 1 9.4 0.4 4.7 3 2 1 4 4 4 0 TATA element modulatory factor 1 DNA binding THP2 PF09432.10 EWM21533.1 - 2.4 8.2 9.7 0.62 10.1 4.4 2.6 2 1 1 3 3 3 0 Tho complex subunit THP2 DUF4407 PF14362.6 EWM21533.1 - 4.6 6.5 32.1 0.54 9.6 12.7 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 EWM21533.1 - 4.9 7.7 14.3 1.5 9.3 1.6 3.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein MetOD2 PF18548.1 EWM21533.1 - 5.9 7.1 14.6 0.48 10.6 5.8 3.1 2 2 1 3 3 3 0 Metanogen output domain 2 Atg14 PF10186.9 EWM21533.1 - 8.8 5.3 25.4 1.8 7.5 2.5 2.4 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ALMT PF11744.8 EWM21533.1 - 9.1 5.0 11.6 17 4.1 0.0 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter TPR_4 PF07721.14 EWM21535.1 - 0.07 13.8 5.3 0.25 12.1 2.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 EWM21535.1 - 0.14 13.0 3.6 0.6 11.1 0.5 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat AMP-binding PF00501.28 EWM21536.1 - 1.4e-09 37.1 0.0 1.7e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme PPR PF01535.20 EWM21537.1 - 0.024 14.9 0.3 0.081 13.2 0.0 1.9 2 0 0 2 2 2 0 PPR repeat PPR_2 PF13041.6 EWM21538.1 - 9.1e-21 73.8 0.0 3.3e-08 33.6 0.0 4.1 1 1 3 4 4 4 4 PPR repeat family PPR PF01535.20 EWM21538.1 - 4.1e-18 64.3 0.0 5e-05 23.3 0.0 4.3 4 0 0 4 4 4 3 PPR repeat PPR_3 PF13812.6 EWM21538.1 - 4.1e-12 46.0 0.0 5.1e-08 32.9 0.0 2.8 1 1 1 3 3 3 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 EWM21538.1 - 1.4e-09 37.5 0.0 0.00011 21.8 0.0 3.8 4 0 0 4 4 4 2 PPR repeat PPR_long PF17177.4 EWM21538.1 - 3.2e-09 36.5 0.0 2.1e-05 24.0 0.0 2.1 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 EWM21538.1 - 0.0012 19.5 0.3 28 5.9 0.1 4.2 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 EWM21538.1 - 0.012 15.5 0.1 4.8 7.4 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EWM21538.1 - 0.087 13.1 0.1 20 5.6 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 EWM21538.1 - 0.12 13.0 1.0 26 5.6 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EWM21538.1 - 0.17 12.1 0.5 42 4.6 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat APOBEC_N PF08210.11 EWM21542.1 - 0.012 15.6 0.1 0.014 15.3 0.1 1.1 1 0 0 1 1 1 0 APOBEC-like N-terminal domain DUF4637 PF15470.6 EWM21543.1 - 0.27 10.9 5.4 0.38 10.5 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) SPT6_acidic PF14632.6 EWM21543.1 - 5.6 7.6 16.0 8.4 7.1 16.0 1.2 1 0 0 1 1 1 0 Acidic N-terminal SPT6 Mito_carr PF00153.27 EWM21544.1 - 3.7e-48 161.4 2.3 3.9e-17 62.0 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Sacchrp_dh_C PF16653.5 EWM21546.1 - 0.15 12.1 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase C-terminal domain Chalcone_2 PF16035.5 EWM21548.1 - 0.055 13.2 0.0 0.055 13.2 0.0 1.1 1 0 0 1 1 1 0 Chalcone isomerase like Gag_spuma PF03276.14 EWM21551.1 - 0.3 9.5 2.0 0.32 9.4 2.0 1.0 1 0 0 1 1 1 0 Spumavirus gag protein Ras PF00071.22 EWM21552.1 - 2.2e-38 131.4 0.8 2.9e-38 131.0 0.8 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EWM21552.1 - 3.3e-18 66.0 0.1 5.3e-18 65.4 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EWM21552.1 - 7.9e-09 35.2 0.1 1.2e-08 34.7 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EWM21552.1 - 1.5e-05 24.6 0.0 1.8e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EWM21552.1 - 5.1e-05 22.7 0.1 5.8e-05 22.6 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF3649 PF12365.8 EWM21553.1 - 0.029 14.1 0.8 0.072 12.8 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3649) U-box PF04564.15 EWM21554.1 - 2.7e-13 49.9 0.0 4.2e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 EWM21554.1 - 3.7e-07 30.2 0.0 5.7e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein DUF2052 PF09747.9 EWM21554.1 - 0.013 15.6 2.3 0.017 15.3 2.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Prothymosin PF03247.14 EWM21554.1 - 0.014 15.9 11.3 0.023 15.2 11.3 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family zf-Nse PF11789.8 EWM21554.1 - 0.023 14.5 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DNA_pol_phi PF04931.13 EWM21554.1 - 0.034 12.3 5.5 0.045 11.9 5.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 EWM21554.1 - 0.037 13.4 0.1 0.04 13.3 0.1 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 EWM21554.1 - 0.076 13.4 2.9 0.14 12.5 2.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.12 EWM21554.1 - 0.16 10.1 4.3 0.19 9.9 4.3 1.1 1 0 0 1 1 1 0 Nop14-like family Paf1 PF03985.13 EWM21554.1 - 0.23 10.4 5.5 0.3 10.0 5.5 1.1 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.14 EWM21554.1 - 1 7.6 4.0 1.2 7.4 4.0 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.12 EWM21554.1 - 2.1 7.6 10.3 3 7.2 10.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4746 PF15928.5 EWM21554.1 - 5.4 6.4 6.4 6.8 6.0 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) GlcNAc PF11397.8 EWM21556.1 - 2e-10 40.6 0.0 2.3e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) COPI_assoc PF08507.10 EWM21558.1 - 1.1e-08 35.2 2.3 1.5e-08 34.8 2.3 1.1 1 0 0 1 1 1 1 COPI associated protein PGG PF13962.6 EWM21558.1 - 0.012 15.4 0.6 0.17 11.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function CTP_transf_1 PF01148.20 EWM21558.1 - 0.013 15.3 4.7 0.016 15.0 4.7 1.0 1 0 0 1 1 1 0 Cytidylyltransferase family AA_permease PF00324.21 EWM21558.1 - 0.25 9.9 9.0 0.027 13.1 2.8 1.9 1 1 1 2 2 2 0 Amino acid permease MARVEL PF01284.23 EWM21558.1 - 0.36 10.8 12.0 2.6 8.1 4.4 2.1 1 1 1 2 2 2 0 Membrane-associating domain Wzy_C_2 PF11846.8 EWM21558.1 - 3.7 7.4 6.7 0.22 11.4 0.6 1.9 2 1 1 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal FbpA PF05833.11 EWM21560.1 - 2.1e-25 89.4 0.0 2.4e-25 89.2 0.0 1.0 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) NAD_binding_10 PF13460.6 EWM21561.1 - 1e-09 38.6 0.0 1e-08 35.3 0.0 2.5 2 1 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EWM21561.1 - 1.6e-06 27.9 0.0 0.00085 18.9 0.2 2.5 2 1 0 2 2 2 2 NmrA-like family Epimerase PF01370.21 EWM21561.1 - 0.00049 19.6 0.0 0.0012 18.3 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EWM21561.1 - 0.043 14.3 0.1 0.071 13.5 0.1 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 EWM21561.1 - 0.053 13.4 0.3 0.081 12.8 0.3 1.2 1 0 0 1 1 1 0 KR domain DapB_N PF01113.20 EWM21561.1 - 0.098 12.8 0.2 0.17 12.0 0.2 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 EWM21561.1 - 0.16 10.9 0.1 0.24 10.4 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Abhydrolase_6 PF12697.7 EWM21562.1 - 1.1e-06 29.4 2.9 1.4e-06 29.0 2.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EWM21562.1 - 1e-05 25.4 0.0 2.3e-05 24.2 0.0 1.4 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_1 PF00561.20 EWM21562.1 - 4.9e-05 23.1 0.0 0.00025 20.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EWM21562.1 - 0.0018 17.6 0.0 0.003 16.9 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 EWM21562.1 - 0.0025 17.7 0.0 0.0045 16.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.22 EWM21562.1 - 0.0036 17.3 0.0 0.0066 16.4 0.0 1.5 1 1 0 1 1 1 1 Cutinase DUF676 PF05057.14 EWM21562.1 - 0.0085 15.6 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF3726 PF12525.8 EWM21562.1 - 0.067 13.3 0.2 0.43 10.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3726) Palm_thioest PF02089.15 EWM21562.1 - 0.25 11.1 0.0 0.36 10.6 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase ABC2_membrane PF01061.24 EWM21564.1 - 2.3e-61 206.9 57.8 9.5e-33 113.4 20.2 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EWM21564.1 - 1e-18 68.2 0.0 1.6e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EWM21564.1 - 0.0018 17.5 45.4 0.028 13.6 20.7 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_29 PF13555.6 EWM21564.1 - 0.0044 16.7 0.1 0.011 15.4 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EWM21564.1 - 0.015 15.2 0.1 0.031 14.2 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_21 PF13304.6 EWM21564.1 - 0.021 14.7 0.0 5.7 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF1974 PF09317.11 EWM21564.1 - 0.13 11.9 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) AAA_25 PF13481.6 EWM21564.1 - 0.14 11.7 0.2 0.37 10.3 0.2 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EWM21564.1 - 0.19 11.9 0.3 0.35 11.1 0.3 1.4 1 0 0 1 1 1 0 AAA domain Evr1_Alr PF04777.13 EWM21565.1 - 2.7e-14 53.4 0.0 5.7e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Erv1 / Alr family Thioredoxin PF00085.20 EWM21565.1 - 4.2e-12 45.9 0.0 7e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin DUF2085 PF09858.9 EWM21565.1 - 0.026 15.0 0.3 0.34 11.4 0.0 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2085) FAD_SOX PF18371.1 EWM21565.1 - 0.069 13.5 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Zn_Tnp_IS1595 PF12760.7 EWM21565.1 - 4.3 7.4 8.2 2.3 8.2 1.7 3.2 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Ribosomal_L37 PF08561.10 EWM21566.1 - 5.4e-09 36.6 3.2 9.4e-07 29.4 0.2 2.2 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L37 DUF676 PF05057.14 EWM21568.1 - 1.9e-36 125.6 0.0 2.9e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EWM21568.1 - 0.27 11.1 0.0 0.34 10.7 0.0 1.1 1 0 0 1 1 1 0 Palmitoyl protein thioesterase TPR_17 PF13431.6 EWM21569.1 - 0.011 16.1 0.0 6.3 7.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EWM21569.1 - 0.02 15.4 2.1 0.079 13.5 0.3 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EWM21569.1 - 0.14 13.1 0.7 0.14 13.1 0.7 4.1 3 2 1 4 4 4 0 Tetratricopeptide repeat Cyt-b5 PF00173.28 EWM21570.1 - 7.5e-13 48.4 0.0 3.2e-12 46.4 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Histone_H2A_C PF16211.5 EWM21571.1 - 1.3e-20 72.8 2.6 2.4e-20 72.0 2.6 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EWM21571.1 - 2e-14 54.0 0.0 2.7e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EWM21571.1 - 0.00016 21.9 0.0 0.00021 21.5 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Chloroa_b-bind PF00504.21 EWM21572.1 - 3.8e-31 108.8 0.4 5e-31 108.4 0.4 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Atu4866 PF11512.8 EWM21572.1 - 0.022 15.1 0.0 0.038 14.4 0.0 1.4 1 0 0 1 1 1 0 Agrobacterium tumefaciens protein Atu4866 Hus1 PF04005.12 EWM21573.1 - 4.8e-30 104.7 0.0 5.4e-30 104.5 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein GerPB PF10803.8 EWM21573.1 - 0.2 11.8 0.1 0.34 11.0 0.1 1.3 1 0 0 1 1 1 0 Spore germination GerPB Pyr_redox_2 PF07992.14 EWM21574.1 - 5.7e-15 55.3 0.0 5.7e-12 45.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EWM21574.1 - 7.9e-11 42.4 0.0 8.5e-08 32.6 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EWM21574.1 - 0.0016 18.4 0.1 0.11 12.5 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding AIF_C PF14721.6 EWM21574.1 - 0.011 16.1 0.0 0.049 14.0 0.0 2.0 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term K_oxygenase PF13434.6 EWM21574.1 - 0.12 11.5 0.0 4.5 6.3 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) ABC_tran PF00005.27 EWM21575.1 - 2.2e-47 161.0 0.4 8.6e-23 81.4 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EWM21575.1 - 1.3e-24 86.1 7.4 6.4e-23 80.6 1.7 3.6 4 0 0 4 4 2 2 ABC transporter AAA_21 PF13304.6 EWM21575.1 - 6e-13 49.3 1.1 0.013 15.3 0.2 4.3 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EWM21575.1 - 1.6e-06 27.8 5.5 0.0086 15.5 0.4 4.4 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EWM21575.1 - 3.2e-06 26.8 0.2 0.0014 18.3 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EWM21575.1 - 6.6e-05 22.9 0.8 0.24 11.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Mg_chelatase PF01078.21 EWM21575.1 - 0.00012 21.6 0.0 0.69 9.2 0.0 3.3 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 EWM21575.1 - 0.00019 21.9 4.5 0.057 13.8 0.0 3.1 3 0 0 3 3 2 2 AAA ATPase domain AAA PF00004.29 EWM21575.1 - 0.00019 21.9 0.0 0.64 10.4 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EWM21575.1 - 0.00037 20.8 1.3 0.22 11.8 0.0 3.6 4 0 0 4 4 3 1 AAA domain Rad17 PF03215.15 EWM21575.1 - 0.0013 18.7 0.0 0.81 9.6 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain MMR_HSR1 PF01926.23 EWM21575.1 - 0.002 18.2 0.1 0.093 12.8 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 EWM21575.1 - 0.0021 18.6 0.3 1.6 9.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 EWM21575.1 - 0.0034 16.9 0.3 0.63 9.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_28 PF13521.6 EWM21575.1 - 0.0043 17.3 0.1 3.7 7.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EWM21575.1 - 0.0081 16.3 0.0 7.2 6.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EWM21575.1 - 0.012 15.5 0.5 3.5 7.5 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_15 PF13175.6 EWM21575.1 - 0.019 14.7 2.9 0.25 11.0 0.0 3.1 4 0 0 4 4 4 0 AAA ATPase domain AAA_14 PF13173.6 EWM21575.1 - 0.022 14.8 0.0 2.7 8.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EWM21575.1 - 0.047 14.1 0.0 6 7.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase ATP-synt_ab PF00006.25 EWM21575.1 - 0.054 13.1 0.0 0.61 9.7 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.6 EWM21575.1 - 0.059 13.9 0.0 0.059 13.9 0.0 4.2 3 1 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 EWM21575.1 - 0.07 12.9 0.1 7.7 6.2 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_5 PF07728.14 EWM21575.1 - 0.11 12.4 0.4 17 5.4 0.1 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.23 EWM21575.1 - 0.16 12.0 0.8 1.9 8.5 0.0 2.7 3 0 0 3 3 3 0 Dynamin family AAA_24 PF13479.6 EWM21575.1 - 0.21 11.3 6.1 1.6 8.4 0.1 3.2 4 0 0 4 4 3 0 AAA domain zf-UBP PF02148.19 EWM21576.1 - 3.7e-16 59.2 8.3 9e-16 58.0 8.3 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Methyltr_RsmB-F PF01189.17 EWM21577.1 - 1.6e-68 230.3 0.0 2.4e-68 229.7 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 EWM21577.1 - 7e-08 32.9 0.0 1.7e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 EWM21577.1 - 0.0013 18.8 0.1 0.0061 16.7 0.0 1.9 1 1 1 2 2 2 1 FtsJ-like methyltransferase Ribosomal_S17e PF00833.18 EWM21578.1 - 3.9e-54 181.8 1.8 4.8e-54 181.5 1.8 1.2 1 0 0 1 1 1 1 Ribosomal S17 WRNPLPNID PF15017.6 EWM21578.1 - 1.2 10.0 5.1 0.54 11.2 2.7 1.6 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box Amidohydro_2 PF04909.14 EWM21579.1 - 6.5e-22 78.7 0.2 1.3e-20 74.4 0.2 2.2 1 1 0 1 1 1 1 Amidohydrolase SMC_N PF02463.19 EWM21580.1 - 5.1e-67 225.5 0.0 8e-67 224.9 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EWM21580.1 - 6.3e-22 78.1 0.0 2.4e-21 76.2 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EWM21580.1 - 3.6e-11 43.4 3.1 1.9e-05 24.6 0.0 3.1 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EWM21580.1 - 3.5e-10 40.1 0.7 3.5e-10 40.1 0.7 3.6 3 1 1 4 4 4 1 AAA ATPase domain AAA_29 PF13555.6 EWM21580.1 - 0.00017 21.3 0.0 0.00036 20.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain BRE1 PF08647.11 EWM21580.1 - 0.039 14.0 0.4 0.039 14.0 0.4 7.8 6 2 0 6 6 6 0 BRE1 E3 ubiquitin ligase DUF87 PF01935.17 EWM21580.1 - 0.3 11.1 0.0 0.3 11.1 0.0 6.0 3 2 0 4 4 4 0 Helicase HerA, central domain ABC_tran PF00005.27 EWM21580.1 - 0.46 11.0 19.1 0.82 10.2 0.1 5.5 3 2 0 4 4 4 0 ABC transporter AAA_23 PF13476.6 EWM21580.1 - 0.58 10.6 93.7 15 6.0 55.0 7.2 2 2 1 4 4 4 0 AAA domain Peptidase_M28 PF04389.17 EWM21582.1 - 1.9e-25 89.7 0.0 3.3e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EWM21582.1 - 1.3e-06 28.3 0.1 2.4e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 PA PF02225.22 EWM21582.1 - 1.8e-05 24.7 0.4 6e-05 23.0 0.2 2.0 2 0 0 2 2 2 1 PA domain DUF572 PF04502.13 EWM21584.1 - 0.29 10.7 18.2 0.41 10.2 18.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) WD40 PF00400.32 EWM21585.1 - 2.8e-21 75.4 1.4 7.5e-06 26.6 0.3 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM21585.1 - 1.5e-09 38.0 0.1 0.065 13.5 0.0 5.1 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EWM21585.1 - 0.0029 17.2 1.1 0.18 11.4 1.2 2.8 2 1 0 2 2 2 1 PQQ-like domain Ge1_WD40 PF16529.5 EWM21585.1 - 0.047 12.6 0.1 3.9 6.4 0.0 2.5 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein LEA_2 PF03168.13 EWM21586.1 - 3.3e-07 30.8 0.0 5.8e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Late embryogenesis abundant protein OppC_N PF12911.7 EWM21586.1 - 0.063 13.3 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Ank_2 PF12796.7 EWM21587.1 - 2.8e-103 338.7 24.7 4.7e-17 62.3 0.2 10.0 5 2 5 10 10 10 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EWM21587.1 - 4.8e-82 269.4 2.4 1.4e-10 41.5 0.2 14.2 7 3 6 14 14 14 12 Ankyrin repeats (many copies) Ank PF00023.30 EWM21587.1 - 1.6e-76 249.7 32.3 8.8e-06 25.9 0.5 18.8 18 1 0 18 18 18 16 Ankyrin repeat Ank_5 PF13857.6 EWM21587.1 - 3.4e-75 247.1 20.5 1.1e-08 35.2 0.3 14.3 6 3 8 15 15 15 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 EWM21587.1 - 3.3e-64 205.2 9.6 0.00084 19.6 0.0 18.2 19 0 0 19 19 19 13 Ankyrin repeat Ricin_B_lectin PF00652.22 EWM21587.1 - 0.0017 18.6 0.5 0.0038 17.5 0.5 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain MatE PF01554.18 EWM21589.1 - 6.3e-23 81.2 26.6 2.1e-14 53.5 8.3 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 EWM21589.1 - 1.7e-09 37.9 8.4 1.7e-09 37.9 8.4 3.8 3 1 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Rad51 PF08423.11 EWM21591.1 - 3.8e-28 98.4 0.0 1.8e-27 96.2 0.0 1.9 2 1 0 2 2 2 1 Rad51 AAA_25 PF13481.6 EWM21591.1 - 3.8e-08 33.2 0.1 5.5e-08 32.6 0.1 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EWM21591.1 - 2.2e-06 27.2 0.1 1.5e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 KaiC AAA_22 PF13401.6 EWM21591.1 - 0.0026 18.0 0.0 0.0049 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 EWM21591.1 - 0.0055 16.2 0.0 0.033 13.7 0.0 1.9 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_16 PF13191.6 EWM21591.1 - 0.051 14.0 0.0 0.077 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain DUF2075 PF09848.9 EWM21591.1 - 0.065 12.5 0.0 0.088 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.19 EWM21591.1 - 0.13 11.8 0.1 0.43 10.2 0.0 1.8 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 EWM21591.1 - 0.14 11.4 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain DUF819 PF05684.12 EWM21592.1 - 2e-26 92.9 22.0 3.5e-23 82.3 15.2 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF819) AMP-binding PF00501.28 EWM21593.1 - 4.1e-91 305.7 0.0 4.9e-91 305.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Iron_traffic PF04362.14 EWM21593.1 - 0.15 11.7 0.0 0.6 9.8 0.0 1.9 2 0 0 2 2 2 0 Bacterial Fe(2+) trafficking DUF4185 PF13810.6 EWM21594.1 - 0.0058 15.9 0.1 0.049 12.9 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4185) ABC2_membrane PF01061.24 EWM21595.1 - 4.5e-81 271.3 45.8 2.3e-41 141.6 11.0 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EWM21595.1 - 5e-52 176.1 0.4 1.3e-24 87.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 EWM21595.1 - 2.5e-19 69.6 44.1 2e-09 37.0 12.4 3.5 2 1 1 3 3 3 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 EWM21595.1 - 1.5e-09 38.0 2.1 0.00017 21.6 0.1 3.0 4 0 0 4 4 3 2 RsgA GTPase AAA_21 PF13304.6 EWM21595.1 - 7.8e-09 35.8 1.0 0.16 11.8 0.0 4.4 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EWM21595.1 - 1e-08 35.0 5.0 0.0042 16.7 0.4 3.4 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EWM21595.1 - 1.3e-06 29.0 1.5 0.01 16.2 0.2 2.6 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 EWM21595.1 - 3.3e-06 26.7 3.3 0.028 13.9 0.2 3.8 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EWM21595.1 - 8.5e-05 22.6 1.6 0.27 11.3 0.2 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 EWM21595.1 - 0.0001 22.9 0.3 0.12 12.9 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EWM21595.1 - 0.00017 21.2 1.7 0.053 13.3 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain Nsp2a_N PF17896.1 EWM21595.1 - 0.0025 17.1 0.3 0.0077 15.5 0.3 1.8 1 0 0 1 1 1 1 Replicase polyprotein 1a N-terminal domain AAA_22 PF13401.6 EWM21595.1 - 0.0026 18.0 1.3 2.5 8.4 0.3 2.7 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EWM21595.1 - 0.0029 17.9 3.6 0.43 10.8 0.0 3.4 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 EWM21595.1 - 0.0031 17.9 0.2 3.7 8.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Rad17 PF03215.15 EWM21595.1 - 0.0034 17.3 0.1 0.22 11.4 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain NACHT PF05729.12 EWM21595.1 - 0.0051 16.8 2.7 1.4 8.8 0.2 2.5 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.6 EWM21595.1 - 0.019 15.5 1.1 3.7 8.1 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EWM21595.1 - 0.043 14.2 3.2 3.7 8.0 0.0 3.7 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 EWM21595.1 - 0.043 13.2 1.2 2.9 7.2 0.1 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATPase_2 PF01637.18 EWM21595.1 - 0.047 13.6 0.1 6.8 6.5 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea SbcCD_C PF13558.6 EWM21595.1 - 0.086 13.1 0.2 5 7.4 0.0 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.23 EWM21595.1 - 0.094 12.8 2.7 9.4 6.3 0.0 2.8 3 0 0 3 3 2 0 Dynamin family Rad51 PF08423.11 EWM21595.1 - 0.11 11.8 0.3 11 5.2 0.0 2.3 2 0 0 2 2 2 0 Rad51 DUF87 PF01935.17 EWM21595.1 - 0.22 11.6 6.6 0.62 10.1 1.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain PduV-EutP PF10662.9 EWM21595.1 - 0.23 11.2 0.8 2.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 EWM21595.1 - 0.42 10.2 2.0 8.3 6.0 0.3 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PhoH PF02562.16 EWM21595.1 - 0.46 9.9 2.3 11 5.4 0.4 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.6 EWM21595.1 - 0.75 9.5 8.3 7 6.3 3.2 2.7 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EWM21595.1 - 1 9.4 3.8 8.8 6.3 0.4 2.7 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) T2SSE PF00437.20 EWM21595.1 - 1 8.3 4.8 1.2 8.1 0.0 2.5 3 0 0 3 3 3 0 Type II/IV secretion system protein Ank_2 PF12796.7 EWM21597.1 - 1.5e-41 140.9 9.6 2.3e-14 53.7 0.3 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EWM21597.1 - 9.1e-31 105.5 12.6 3.1e-09 36.9 0.0 6.5 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 EWM21597.1 - 5.1e-28 97.1 14.3 8.9e-09 35.7 0.1 6.3 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 EWM21597.1 - 7.5e-25 86.2 8.2 0.0006 20.2 0.1 7.3 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 EWM21597.1 - 1.6e-21 74.1 4.4 0.025 15.1 0.1 7.4 8 0 0 8 8 8 6 Ankyrin repeat LSM PF01423.22 EWM21598.1 - 1.8e-20 72.4 0.1 2.4e-20 72.0 0.1 1.2 1 0 0 1 1 1 1 LSM domain TRAM_LAG1_CLN8 PF03798.16 EWM21599.1 - 2.9e-37 128.3 24.0 2.9e-37 128.3 24.0 1.7 2 0 0 2 2 2 1 TLC domain Sedlin_N PF04628.13 EWM21600.1 - 4.6e-22 78.6 0.0 6e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 EWM21600.1 - 0.009 15.9 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Antimicrobial19 PF08225.11 EWM21600.1 - 0.036 13.7 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 Pseudin antimicrobial peptide zf-RING_4 PF14570.6 EWM21601.1 - 4.9e-19 67.9 19.1 9e-19 67.0 19.1 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 EWM21601.1 - 9.9e-06 25.3 0.0 1.7e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 EWM21601.1 - 6e-05 22.8 15.5 0.00011 22.0 15.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Atrophin-1 PF03154.15 EWM21601.1 - 0.00042 18.8 3.5 0.00042 18.8 3.5 2.5 2 0 0 2 2 2 1 Atrophin-1 family SSFA2_C PF14723.6 EWM21601.1 - 0.027 14.4 0.8 0.027 14.4 0.8 2.2 2 0 0 2 2 2 0 Sperm-specific antigen 2 C-terminus zf-UDP PF14569.6 EWM21601.1 - 0.19 11.9 6.8 0.43 10.7 6.8 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger NCA2 PF08637.10 EWM21603.1 - 1.9e-40 138.8 0.1 2.7e-40 138.4 0.1 1.2 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 TRAM_LAG1_CLN8 PF03798.16 EWM21604.1 - 0.00018 21.3 24.2 0.00019 21.2 22.8 1.8 2 0 0 2 2 2 1 TLC domain Peptidase_M49 PF03571.15 EWM21607.1 - 2.3e-215 716.2 0.0 2.7e-215 715.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 Aminotran_5 PF00266.19 EWM21608.1 - 1.4e-28 99.9 0.0 2.1e-19 69.8 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Aminotran_1_2 PF00155.21 EWM21608.1 - 0.036 13.2 0.0 6 5.9 0.0 2.3 2 0 0 2 2 2 0 Aminotransferase class I and II TPR_9 PF13371.6 EWM21609.1 - 0.0057 16.8 4.6 0.0068 16.5 3.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.18 EWM21609.1 - 0.014 15.4 0.1 0.049 13.7 0.1 1.8 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 EWM21609.1 - 0.12 12.6 1.0 25 5.3 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Ofd1_CTDD PF10637.9 EWM21609.1 - 0.14 11.5 0.6 0.42 9.9 0.2 1.7 1 1 1 2 2 2 0 Oxoglutarate and iron-dependent oxygenase degradation C-term CutC PF03932.14 EWM21610.1 - 2.2e-54 184.0 0.0 2.7e-54 183.7 0.0 1.1 1 0 0 1 1 1 1 CutC family BRO1 PF03097.18 EWM21611.1 - 1.4e-31 109.7 0.0 1.8e-31 109.4 0.0 1.0 1 0 0 1 1 1 1 BRO1-like domain DUF5355 PF17306.2 EWM21611.1 - 0.00035 19.7 0.0 0.00055 19.1 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5355) TrbI_Ftype PF09677.10 EWM21611.1 - 0.21 11.9 2.7 0.38 11.1 0.1 2.6 2 1 1 3 3 3 0 Type-F conjugative transfer system protein (TrbI_Ftype) Glyco_transf_24 PF18404.1 EWM21612.1 - 3.2e-139 462.9 2.3 4.8e-139 462.3 2.3 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 EWM21612.1 - 4e-33 115.4 0.0 1.3e-32 113.8 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 EWM21612.1 - 1.3e-25 90.4 0.0 2.9e-25 89.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 EWM21612.1 - 6.2e-20 71.5 0.4 2.5e-18 66.3 0.0 3.5 5 0 0 5 5 5 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 EWM21612.1 - 1.1e-18 67.3 0.0 2.3e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 EWM21612.1 - 2.6e-05 23.9 0.2 4.3e-05 23.2 0.2 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Thioredoxin_15 PF18403.1 EWM21612.1 - 0.00083 19.3 0.0 1 9.3 0.0 2.8 3 1 0 3 3 3 2 Thioredoxin-like domain DUF982 PF06169.12 EWM21612.1 - 0.33 11.0 2.7 18 5.4 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF982) Lipase_3 PF01764.25 EWM21613.1 - 2.1e-08 34.2 0.0 3.4e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EWM21613.1 - 0.0016 19.1 0.4 0.0081 16.8 0.1 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.20 EWM21613.1 - 0.003 17.2 0.0 0.0071 16.0 0.0 1.6 1 1 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 EWM21613.1 - 0.0052 16.5 0.0 0.0099 15.6 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 EWM21613.1 - 0.042 13.1 0.0 0.069 12.4 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF676 PF05057.14 EWM21613.1 - 0.089 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LIDHydrolase PF10230.9 EWM21613.1 - 0.21 11.1 0.0 0.34 10.4 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase RmlD_sub_bind PF04321.17 EWM21616.1 - 3.6e-10 39.4 0.0 1.5e-08 34.1 0.0 2.4 3 0 0 3 3 3 2 RmlD substrate binding domain Epimerase PF01370.21 EWM21616.1 - 1.9e-05 24.3 0.0 0.014 14.9 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EWM21617.1 - 4.3e-21 75.3 0.0 1.1e-19 70.7 0.0 2.4 3 0 0 3 3 3 1 RmlD substrate binding domain Epimerase PF01370.21 EWM21617.1 - 5.9e-20 71.8 0.0 2.9e-17 62.9 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EWM21617.1 - 1.5e-17 64.0 0.0 2.1e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EWM21617.1 - 2.6e-08 33.2 0.0 3.6e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EWM21617.1 - 4.4e-08 32.6 0.0 7.5e-06 25.3 0.0 2.1 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EWM21617.1 - 0.0041 16.3 0.0 0.99 8.5 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein YAcAr PF10686.9 EWM21617.1 - 0.026 14.4 0.0 0.057 13.4 0.0 1.6 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family KR PF08659.10 EWM21617.1 - 0.048 13.6 0.0 0.077 12.9 0.0 1.2 1 0 0 1 1 1 0 KR domain LSM PF01423.22 EWM21619.1 - 2.1e-18 65.7 1.8 2.7e-18 65.4 1.8 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EWM21619.1 - 0.0021 18.1 0.2 0.003 17.6 0.2 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Hfq PF17209.3 EWM21619.1 - 0.05 13.3 0.1 0.067 12.9 0.1 1.3 1 0 0 1 1 1 0 Hfq protein LSM PF01423.22 EWM21620.1 - 7.6e-20 70.4 1.6 9.5e-20 70.1 1.6 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EWM21620.1 - 0.00097 19.2 0.2 0.0012 18.9 0.2 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Gemin7 PF11095.8 EWM21620.1 - 0.01 15.7 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) Hfq PF17209.3 EWM21620.1 - 0.037 13.7 0.1 0.052 13.2 0.1 1.3 1 0 0 1 1 1 0 Hfq protein Tail_tube PF10618.9 EWM21620.1 - 0.12 12.2 0.3 0.22 11.4 0.3 1.5 1 1 0 1 1 1 0 Phage tail tube protein TFIIS_C PF01096.18 EWM21621.1 - 2.8e-16 59.1 3.9 5.1e-16 58.2 3.9 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) TFIIS_M PF07500.14 EWM21621.1 - 7.8e-14 52.1 0.2 1.6e-13 51.1 0.1 1.6 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain Med26 PF08711.11 EWM21621.1 - 1.6e-05 24.8 0.0 4e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF3385 PF11865.8 EWM21622.1 - 8.8e-05 22.5 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3385) Telomere_reg-2 PF10193.9 EWM21622.1 - 0.018 15.5 0.0 0.033 14.6 0.0 1.4 1 0 0 1 1 1 0 Telomere length regulation protein CH PF00307.31 EWM21623.1 - 1.8e-41 140.7 0.1 1.4e-19 70.3 0.0 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EWM21623.1 - 5.5e-06 26.1 0.0 0.00048 19.9 0.0 2.5 2 0 0 2 2 2 1 CAMSAP CH domain Spectrin PF00435.21 EWM21623.1 - 0.0014 19.1 10.4 0.023 15.2 0.1 5.0 4 1 2 6 6 6 2 Spectrin repeat AXIN1_TNKS_BD PF16646.5 EWM21623.1 - 0.74 10.8 0.0 0.74 10.8 0.0 2.8 3 0 0 3 3 3 0 Axin-1 tankyrase binding domain Ufm1 PF03671.14 EWM21624.1 - 1.7e-39 133.7 0.1 2.1e-39 133.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein AP2 PF00847.20 EWM21624.1 - 0.1 12.9 0.4 0.19 12.0 0.4 1.5 1 0 0 1 1 1 0 AP2 domain PARP_regulatory PF01358.18 EWM21625.1 - 1.1e-10 41.0 0.0 1.7e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Poly A polymerase regulatory subunit PI3_PI4_kinase PF00454.27 EWM21626.1 - 2.4e-45 155.3 0.0 3.9e-45 154.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 EWM21626.1 - 3.2e-15 56.2 0.0 5.5e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 FAT domain FATC PF02260.20 EWM21626.1 - 5.8e-15 54.8 0.3 1.3e-14 53.7 0.3 1.6 1 0 0 1 1 1 1 FATC domain Eaf7 PF07904.13 EWM21626.1 - 0.029 14.8 0.0 0.065 13.6 0.0 1.5 1 0 0 1 1 1 0 Chromatin modification-related protein EAF7 DUF4135 PF13575.6 EWM21626.1 - 0.061 12.6 0.0 0.34 10.2 0.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4135) Snf7 PF03357.21 EWM21627.1 - 2.6e-36 124.8 13.5 3.4e-36 124.4 13.5 1.1 1 0 0 1 1 1 1 Snf7 PspA_IM30 PF04012.12 EWM21627.1 - 0.17 11.4 13.8 2.2 7.8 6.3 2.2 1 1 1 2 2 2 0 PspA/IM30 family EcoR124_C PF12008.8 EWM21627.1 - 0.85 9.2 7.1 0.47 10.1 4.6 1.7 1 1 1 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal D5_N PF08706.11 EWM21627.1 - 1.9 8.7 6.5 0.72 10.1 3.4 1.7 2 0 0 2 2 2 0 D5 N terminal like Snf7 PF03357.21 EWM21628.1 - 2.4e-36 125.0 13.5 3.1e-36 124.6 13.5 1.1 1 0 0 1 1 1 1 Snf7 PspA_IM30 PF04012.12 EWM21628.1 - 0.15 11.6 13.8 1.9 8.0 6.3 2.2 1 1 1 2 2 2 0 PspA/IM30 family EcoR124_C PF12008.8 EWM21628.1 - 0.62 9.7 6.8 0.49 10.0 4.5 1.7 1 1 0 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal D5_N PF08706.11 EWM21628.1 - 2.7 8.3 6.5 0.95 9.7 3.4 1.8 2 0 0 2 2 2 0 D5 N terminal like Patatin PF01734.22 EWM21629.1 - 4.6e-09 36.8 1.0 1.6e-06 28.4 1.0 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase Ctf8 PF09696.10 EWM21630.1 - 4.4e-15 56.3 0.0 1.3e-14 54.7 0.0 1.8 1 1 0 1 1 1 1 Ctf8 Glucosamine_iso PF01182.20 EWM21631.1 - 1.8e-61 207.9 0.0 2.2e-61 207.6 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Thioredoxin PF00085.20 EWM21632.1 - 0.22 11.5 0.0 0.38 10.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin DNA_pol_B_thumb PF14791.6 EWM21633.1 - 1.6e-15 57.0 0.0 3.6e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 EWM21633.1 - 2.5e-08 33.6 0.0 6.4e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 EWM21633.1 - 3.6e-07 30.5 0.0 4.1e-06 27.1 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_B_palm PF14792.6 EWM21633.1 - 6.2e-05 23.2 0.0 0.00012 22.3 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm BRCT_2 PF16589.5 EWM21633.1 - 0.00038 20.8 0.0 0.0014 19.0 0.0 2.0 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain HHH_5 PF14520.6 EWM21633.1 - 0.059 14.0 0.0 0.16 12.6 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain DNA_pol_B_thumb PF14791.6 EWM21634.1 - 1.4e-15 57.2 0.0 3.6e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 EWM21634.1 - 2.5e-08 33.6 0.0 6.4e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 EWM21634.1 - 3.6e-07 30.5 0.0 4.1e-06 27.1 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_B_palm PF14792.6 EWM21634.1 - 6.2e-05 23.2 0.0 0.00012 22.3 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm BRCT_2 PF16589.5 EWM21634.1 - 0.00036 20.9 0.0 0.0014 19.0 0.0 2.0 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain HHH_5 PF14520.6 EWM21634.1 - 0.059 14.0 0.0 0.16 12.6 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain FIBP PF05427.11 EWM21636.1 - 3e-41 141.9 0.0 1e-27 97.4 0.0 3.7 2 2 1 3 3 3 3 Acidic fibroblast growth factor binding (FIBP) Antistasin PF02822.14 EWM21636.1 - 0.27 11.9 2.0 0.97 10.1 0.1 2.4 2 0 0 2 2 2 0 Antistasin family 5TM-5TMR_LYT PF07694.12 EWM21637.1 - 0.011 15.3 2.4 0.011 15.3 2.4 1.9 2 0 0 2 2 2 0 5TMR of 5TMR-LYT MscS_porin PF12795.7 EWM21637.1 - 0.077 12.5 2.5 0.14 11.6 2.5 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Sulfotransfer_1 PF00685.27 EWM21638.1 - 1.6e-05 24.5 0.0 3.9e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EWM21638.1 - 0.0011 19.4 0.4 0.12 12.8 0.0 3.0 1 1 1 3 3 3 1 Sulfotransferase family Glycos_transf_4 PF00953.21 EWM21639.1 - 7.7e-35 120.2 8.7 7.7e-35 120.2 8.7 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 4 DUF2644 PF10841.8 EWM21639.1 - 0.042 14.1 0.2 0.2 11.9 0.2 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2644) S1FA PF04689.13 EWM21639.1 - 1.4 9.2 0.0 1.4 9.2 0.0 2.8 3 0 0 3 3 3 0 DNA binding protein S1FA DUF4714 PF15833.5 EWM21639.1 - 2.5 8.1 6.3 0.66 9.9 1.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4714) Pex24p PF06398.11 EWM21641.1 - 1.7e-11 43.8 2.5 3.4e-11 42.7 2.5 1.6 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin cwf21 PF08312.12 EWM21643.1 - 6.4e-11 42.2 4.7 6.4e-11 42.2 4.7 2.4 2 0 0 2 2 2 1 cwf21 domain Phage_B PF02304.15 EWM21643.1 - 0.39 11.1 5.6 2.8 8.3 1.6 2.6 2 0 0 2 2 2 0 Scaffold protein B DUF5333 PF17267.2 EWM21643.1 - 0.63 10.3 5.9 0.1 12.8 1.2 2.2 2 1 0 2 2 2 0 Family of unknown function (DUF5333) Ribosomal_L6e PF01159.19 EWM21645.1 - 1.4e-33 115.7 0.2 2.2e-33 115.1 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e DUF4920 PF16267.5 EWM21645.1 - 0.077 13.0 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4920) FSIP1 PF15554.6 EWM21645.1 - 0.078 12.1 0.1 0.094 11.8 0.1 1.1 1 0 0 1 1 1 0 FSIP1 family RRM_1 PF00076.22 EWM21646.1 - 5.8e-23 80.5 0.5 2e-09 37.2 0.0 4.8 3 2 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EWM21646.1 - 0.0065 16.3 0.0 15 5.5 0.0 3.2 3 0 0 3 3 3 2 Occluded RNA-recognition motif Apt1 PF10351.9 EWM21646.1 - 0.01 14.7 2.7 0.016 14.1 2.7 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Keratin_2_head PF16208.5 EWM21646.1 - 7.8 6.6 14.4 0.13 12.4 6.6 2.0 2 0 0 2 2 2 0 Keratin type II head HAD_2 PF13419.6 EWM21647.1 - 3e-18 66.5 0.0 7.8e-18 65.2 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EWM21647.1 - 1.1e-09 38.9 0.0 1.8e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EWM21647.1 - 5.8e-05 23.1 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like NFACT-R_1 PF05670.13 EWM21648.1 - 7.2e-30 103.8 0.0 1.5e-29 102.8 0.0 1.6 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-C PF11923.8 EWM21648.1 - 5.2e-27 93.8 0.0 1.2e-26 92.7 0.0 1.6 1 0 0 1 1 1 1 NFACT protein C-terminal domain FAD_binding_4 PF01565.23 EWM21649.1 - 3.6e-10 39.7 0.0 5.8e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Glyoxalase PF00903.25 EWM21649.1 - 0.055 13.7 0.0 5.1 7.3 0.0 2.5 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Pyr_redox_2 PF07992.14 EWM21650.1 - 7.4e-42 143.6 0.1 9e-42 143.3 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EWM21650.1 - 5.2e-16 59.0 0.3 1.9e-12 47.5 0.8 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EWM21650.1 - 2.3e-07 30.7 8.2 0.0084 15.7 1.4 4.4 4 1 1 5 5 5 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EWM21650.1 - 3.6e-07 30.3 0.6 0.038 14.0 0.1 3.5 3 1 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EWM21650.1 - 3e-06 27.4 0.3 0.098 12.9 0.2 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EWM21650.1 - 0.0018 17.5 0.0 0.0084 15.3 0.0 2.0 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EWM21650.1 - 0.027 13.7 0.0 0.09 12.0 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF2124 PF09897.9 EWM21650.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2124) Trp_halogenase PF04820.14 EWM21650.1 - 0.13 11.1 0.1 1.6 7.5 0.2 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Histone PF00125.24 EWM21651.1 - 1e-18 67.9 0.0 1.3e-18 67.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 EWM21651.1 - 0.00098 19.6 0.0 0.0016 18.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 EWM21651.1 - 0.023 15.0 0.0 0.048 14.0 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RNase_II_C_S1 PF18614.1 EWM21652.1 - 0.1 12.6 1.0 0.42 10.6 1.0 2.1 1 0 0 1 1 1 0 RNase II-type exonuclease C-terminal S1 domain TPR_7 PF13176.6 EWM21652.1 - 0.12 12.5 0.4 1.6 8.9 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EWM21652.1 - 0.42 11.6 4.7 1.2 10.2 1.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat HEAT PF02985.22 EWM21653.1 - 2e-09 36.9 17.8 0.0053 16.9 0.0 8.5 9 0 0 9 9 9 2 HEAT repeat HEAT_2 PF13646.6 EWM21653.1 - 1.8e-07 31.5 5.3 0.0081 16.5 0.1 5.3 5 1 0 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 EWM21653.1 - 1.8e-06 28.3 9.8 0.43 11.2 0.0 6.2 6 1 1 7 7 7 4 HEAT-like repeat Cnd1 PF12717.7 EWM21653.1 - 1.7e-05 24.9 5.9 0.12 12.4 0.0 5.7 6 1 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EWM21653.1 - 0.00071 20.1 0.0 3.8 8.2 0.0 4.6 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region UME PF08064.13 EWM21653.1 - 0.0038 17.1 0.2 2.2 8.3 0.1 3.8 3 1 0 3 3 3 1 UME (NUC010) domain CLASP_N PF12348.8 EWM21653.1 - 0.0092 15.6 1.6 1.7 8.1 0.1 4.2 4 1 0 4 4 4 1 CLASP N terminal TAF6_C PF07571.13 EWM21653.1 - 0.064 13.6 1.0 4.8 7.6 0.0 3.6 4 0 0 4 4 4 0 TAF6 C-terminal HEAT repeat domain DUF3437 PF11919.8 EWM21653.1 - 0.1 12.5 0.1 1.3 9.0 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) DUF4042 PF13251.6 EWM21653.1 - 0.36 10.5 2.9 6.6 6.4 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4042) tRNA-synt_2 PF00152.20 EWM21654.1 - 1.3e-08 34.3 0.0 1.5e-08 34.2 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Glycos_transf_2 PF00535.26 EWM21655.1 - 3.5e-15 56.2 0.0 5.9e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 EWM21655.1 - 8.4e-07 28.7 0.0 6.5e-05 22.5 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 EWM21655.1 - 0.0002 21.3 0.0 0.00033 20.6 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 DUF4543 PF15076.6 EWM21655.1 - 0.16 12.2 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4543) tRNA-synt_2 PF00152.20 EWM21656.1 - 1.3e-12 47.4 0.0 1.6e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) GST_C_6 PF17171.4 EWM21656.1 - 0.00019 21.2 0.0 0.00047 19.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EWM21656.1 - 0.077 13.0 0.0 0.19 11.8 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain tRNA-synt_2d PF01409.20 EWM21656.1 - 0.27 10.7 0.0 0.38 10.2 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) LRR_6 PF13516.6 EWM21657.1 - 0.068 13.3 1.9 0.87 9.8 0.2 3.0 3 0 0 3 3 3 0 Leucine Rich repeat CDC45 PF02724.14 EWM21657.1 - 0.3 9.3 13.7 0.44 8.8 13.7 1.3 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 EWM21657.1 - 1.9 7.7 20.2 2.3 7.4 20.2 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 EWM21657.1 - 2.7 7.4 25.2 3.7 6.9 25.2 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EWM21657.1 - 8.3 4.5 25.4 12 4.0 25.4 1.2 1 0 0 1 1 1 0 Nop14-like family fn3 PF00041.21 EWM21658.1 - 2e-08 34.4 0.0 5.6e-08 33.0 0.0 1.7 1 1 0 1 1 1 1 Fibronectin type III domain Nop14 PF04147.12 EWM21658.1 - 5.5 5.1 8.9 6.4 4.9 8.9 1.0 1 0 0 1 1 1 0 Nop14-like family Trypsin_2 PF13365.6 EWM21659.1 - 2.6e-35 122.5 0.6 5.2e-35 121.6 0.6 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 EWM21659.1 - 4.6e-17 62.6 0.0 6.7e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Trypsin Peptidase_S32 PF05579.13 EWM21659.1 - 0.0035 16.6 0.5 0.31 10.2 0.0 2.2 2 0 0 2 2 2 2 Equine arteritis virus serine endopeptidase S32 SPX PF03105.19 EWM21659.1 - 0.0049 16.8 1.1 0.0051 16.8 1.1 1.1 1 0 0 1 1 1 1 SPX domain Peptidase_S29 PF02907.15 EWM21659.1 - 0.0083 15.9 0.1 0.019 14.7 0.1 1.6 1 0 0 1 1 1 1 Hepatitis C virus NS3 protease Peptidase_S46 PF10459.9 EWM21659.1 - 0.073 11.7 0.5 0.39 9.3 0.3 1.8 2 0 0 2 2 2 0 Peptidase S46 Ank_2 PF12796.7 EWM21661.1 - 3.3e-49 165.4 0.0 3.1e-13 50.1 0.0 4.6 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EWM21661.1 - 1.8e-34 117.7 1.2 7.8e-09 35.9 0.2 6.4 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 EWM21661.1 - 5.8e-32 108.7 5.3 0.00074 19.9 0.0 8.4 8 0 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.6 EWM21661.1 - 1.3e-30 105.0 2.4 6.2e-07 29.6 0.0 6.0 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EWM21661.1 - 6.2e-27 90.7 3.8 0.007 16.8 0.1 8.9 8 1 0 8 8 8 6 Ankyrin repeat fn3 PF00041.21 EWM21661.1 - 0.023 15.0 0.0 0.047 14.0 0.0 1.5 1 0 0 1 1 1 0 Fibronectin type III domain FHA PF00498.26 EWM21662.1 - 4.8e-17 62.1 0.0 7.9e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EWM21662.1 - 1.2e-06 28.8 0.0 2.3e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Beta-lactamase PF00144.24 EWM21663.1 - 4.2e-22 78.8 0.0 5.7e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Clat_adaptor_s PF01217.20 EWM21665.1 - 1.9e-56 189.9 2.1 2.4e-56 189.6 2.1 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1878 PF08963.10 EWM21665.1 - 0.048 14.2 0.1 0.074 13.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1878) GPI-anchored PF10342.9 EWM21666.1 - 0.069 13.9 0.0 0.14 12.9 0.0 1.5 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Ribosomal_60s PF00428.19 EWM21668.1 - 3.4e-13 50.0 9.5 4.5e-13 49.6 9.5 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein HscB_4_cys PF18256.1 EWM21669.1 - 9.7 6.1 11.5 5.3 7.0 2.9 3.0 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif Tim17 PF02466.19 EWM21671.1 - 9.3e-07 29.2 11.0 1.1e-06 29.0 11.0 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_YMGG PF13441.6 EWM21671.1 - 2e-06 27.4 10.1 0.00033 20.3 0.3 2.6 2 1 0 2 2 2 2 YMGG-like Gly-zipper Romo1 PF10247.9 EWM21671.1 - 0.0029 18.0 0.6 0.0029 18.0 0.6 2.4 2 1 0 2 2 2 1 Reactive mitochondrial oxygen species modulator 1 Gly-zipper_OmpA PF13436.6 EWM21671.1 - 0.015 15.1 0.7 0.015 15.1 0.7 3.4 3 1 0 3 3 3 0 Glycine-zipper domain DUF1269 PF06897.12 EWM21671.1 - 1.4 9.3 9.2 0.5 10.7 0.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1269) Bacteriocin_IIc PF10439.9 EWM21671.1 - 3.1 8.0 20.5 0.81 9.8 6.5 2.6 1 1 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_Omp PF13488.6 EWM21671.1 - 6.1 6.9 20.5 0.21 11.6 2.0 2.9 2 1 0 2 2 2 0 Glycine zipper Tim17 PF02466.19 EWM21672.1 - 6.2e-06 26.6 10.0 7.3e-06 26.3 10.0 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_YMGG PF13441.6 EWM21672.1 - 0.0023 17.6 12.8 0.15 11.9 1.2 2.7 2 1 0 2 2 2 2 YMGG-like Gly-zipper Romo1 PF10247.9 EWM21672.1 - 0.12 12.7 6.5 0.17 12.3 0.2 2.4 2 1 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 DUF1269 PF06897.12 EWM21672.1 - 0.85 9.9 7.9 0.79 10.0 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1269) Bacteriocin_IIc PF10439.9 EWM21672.1 - 3.3 7.9 17.7 0.74 10.0 6.8 2.5 1 1 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide FYVE PF01363.21 EWM21674.1 - 5.7e-14 52.0 6.4 5.7e-14 52.0 6.4 2.2 2 0 0 2 2 2 1 FYVE zinc finger Ribosomal_L3 PF00297.22 EWM21675.1 - 1.2e-78 264.7 2.9 1.4e-78 264.4 2.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Cytochrom_B562 PF07361.11 EWM21675.1 - 0.062 14.0 0.2 0.38 11.4 0.0 2.0 2 0 0 2 2 2 0 Cytochrome b562 RNase_T PF00929.24 EWM21677.1 - 0.0021 18.6 0.0 0.0033 18.0 0.0 1.3 1 0 0 1 1 1 1 Exonuclease MFS_1 PF07690.16 EWM21678.1 - 1.9e-22 79.7 16.8 2.5e-22 79.3 16.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EWM21678.1 - 7.1e-05 21.8 10.2 0.00068 18.6 10.2 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter LacY_symp PF01306.19 EWM21678.1 - 0.87 8.3 13.1 3.3 6.4 12.8 1.8 1 1 0 1 1 1 0 LacY proton/sugar symporter AAA_lid_2 PF17863.1 EWM21679.1 - 0.051 13.4 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 AAA lid domain Myb_DNA-binding PF00249.31 EWM21680.1 - 9.7e-28 96.1 7.9 1.6e-14 53.8 0.8 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EWM21680.1 - 9.1e-23 80.3 3.2 1.5e-14 53.9 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EWM21680.1 - 0.088 12.7 0.3 0.3 11.0 0.1 1.8 1 1 1 2 2 2 0 Myb DNA-binding like SLIDE PF09111.10 EWM21680.1 - 0.1 12.7 0.1 3.8 7.6 0.0 2.2 2 0 0 2 2 2 0 SLIDE Sec23_helical PF04815.15 EWM21682.1 - 6.6e-23 80.5 0.1 1.9e-22 79.0 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EWM21682.1 - 2e-11 44.5 0.0 3.6e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 EWM21682.1 - 0.0053 16.6 0.0 0.0097 15.8 0.0 1.4 1 0 0 1 1 1 1 Gelsolin repeat GCS PF03074.16 EWM21683.1 - 1.2e-37 130.2 0.0 1.4e-37 130.0 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase DUF1479 PF07350.12 EWM21683.1 - 0.07 11.9 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) S1 PF00575.23 EWM21684.1 - 0.12 12.8 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 S1 RNA binding domain Umbravirus_LDM PF04817.12 EWM21684.1 - 0.12 11.7 0.1 0.17 11.2 0.1 1.2 1 0 0 1 1 1 0 Umbravirus long distance movement (LDM) family TPR_10 PF13374.6 EWM21687.1 - 0.097 12.6 0.4 0.097 12.6 0.4 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC5 PF12862.7 EWM21687.1 - 0.15 12.2 0.3 1.2 9.3 0.3 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 5 TPR_2 PF07719.17 EWM21687.1 - 0.18 12.0 2.7 0.21 11.8 0.5 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 EWM21687.1 - 0.43 11.3 5.6 0.73 10.5 0.4 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EWM21687.1 - 1.2 9.9 5.0 0.89 10.3 0.7 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DEK_C PF08766.11 EWM21689.1 - 0.064 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 DEK C terminal domain DUF4633 PF15464.6 EWM21689.1 - 0.15 12.2 0.4 10 6.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4633) CRCB PF02537.15 EWM21691.1 - 2e-08 34.4 0.6 3e-08 33.9 0.6 1.2 1 0 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) DUF4614 PF15391.6 EWM21692.1 - 0.014 15.4 5.3 0.022 14.7 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Asp PF00026.23 EWM21692.1 - 0.024 14.1 0.0 0.024 14.1 0.0 2.8 3 0 0 3 3 3 0 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 EWM21692.1 - 0.024 15.3 0.1 1.4 9.6 0.0 2.6 2 0 0 2 2 2 0 Aspartyl protease Apt1 PF10351.9 EWM21692.1 - 0.049 12.5 2.0 0.058 12.2 2.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SR-25 PF10500.9 EWM21692.1 - 0.18 11.4 25.9 0.094 12.3 23.2 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CCDC106 PF15794.5 EWM21692.1 - 1.6 8.4 6.4 2.5 7.7 6.4 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Chorion_2 PF03964.15 EWM21692.1 - 2.1 9.2 13.0 5.4 7.9 13.0 1.6 1 0 0 1 1 1 0 Chorion family 2 CDK2AP PF09806.9 EWM21692.1 - 3.9 7.5 7.6 6.3 6.8 7.6 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF1635 PF07795.11 EWM21692.1 - 9.7 6.0 7.1 15 5.3 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Mito_carr PF00153.27 EWM21694.1 - 5.9e-43 144.7 0.7 6e-20 71.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PT-VENN PF04829.13 EWM21694.1 - 0.2 11.8 0.9 11 6.3 0.1 2.6 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif PhyH PF05721.13 EWM21695.1 - 8.8e-21 75.1 0.1 2e-20 74.0 0.1 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.6 EWM21695.1 - 0.016 16.1 0.0 0.027 15.4 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF2237 PF09996.9 EWM21702.1 - 3.2e-51 172.1 0.0 4.9e-51 171.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) SBF_like PF13593.6 EWM21704.1 - 1.6e-34 119.7 12.3 2.5e-34 119.0 12.3 1.2 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 EWM21704.1 - 1.1e-06 28.4 8.0 1.9e-06 27.7 8.0 1.3 1 0 0 1 1 1 1 Sodium Bile acid symporter family zf_Rg PF17915.1 EWM21704.1 - 0.01 15.2 0.0 0.13 11.7 0.0 2.2 2 0 0 2 2 2 0 Reverse gyrase zinc finger K_channel_TID PF07941.11 EWM21708.1 - 3.8 8.0 19.8 0.12 12.9 6.7 3.9 4 0 0 4 4 4 0 Potassium channel Kv1.4 tandem inactivation domain LRR_6 PF13516.6 EWM21709.1 - 0.15 12.2 0.4 16 5.9 0.0 3.2 3 0 0 3 3 3 0 Leucine Rich repeat PI3_PI4_kinase PF00454.27 EWM21711.1 - 1.3e-32 113.6 0.0 2e-24 86.8 0.0 2.6 3 0 0 3 3 3 2 Phosphatidylinositol 3- and 4-kinase SMG1 PF15785.5 EWM21711.1 - 1.6e-21 76.4 0.4 1.6e-07 30.2 0.0 3.2 3 0 0 3 3 3 3 Serine/threonine-protein kinase smg-1 FATC PF02260.20 EWM21711.1 - 2.9e-10 39.8 0.0 7.2e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 FATC domain RasGEF_N_2 PF14663.6 EWM21711.1 - 0.11 12.9 0.0 0.75 10.2 0.0 2.5 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain GDP_Man_Dehyd PF16363.5 EWM21711.1 - 0.56 9.5 3.3 0.98 8.7 3.3 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Na_H_Exchanger PF00999.21 EWM21712.1 - 7.2e-16 57.9 10.7 1.1e-15 57.4 10.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Asp-Al_Ex PF06826.12 EWM21712.1 - 0.0086 15.9 1.6 0.0086 15.9 1.6 2.0 1 1 1 2 2 2 1 Predicted Permease Membrane Region Lipase_GDSL_2 PF13472.6 EWM21715.1 - 2.7e-24 86.5 0.1 4e-24 86.0 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EWM21715.1 - 7.3e-16 58.7 0.0 1.2e-15 58.1 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Chalcone_3 PF16036.5 EWM21716.1 - 2.5e-11 44.0 3.0 3.5e-10 40.2 0.2 2.8 2 1 0 2 2 2 1 Chalcone isomerase-like Chalcone_2 PF16035.5 EWM21716.1 - 1.4e-08 34.8 2.4 0.0025 17.6 0.1 3.1 3 0 0 3 3 3 2 Chalcone isomerase like Chalcone PF02431.15 EWM21716.1 - 0.00018 21.0 0.0 0.034 13.5 0.0 2.2 2 0 0 2 2 2 2 Chalcone-flavanone isomerase TFIIA PF03153.13 EWM21716.1 - 0.022 14.7 11.3 0.03 14.3 11.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCSAP PF15748.5 EWM21718.1 - 0.096 12.9 11.2 0.13 12.4 11.2 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Hexapep PF00132.24 EWM21719.1 - 3.6e-08 32.8 7.8 0.033 13.9 0.0 3.9 1 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 EWM21719.1 - 2e-07 30.9 0.0 3.4e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EWM21719.1 - 0.0015 19.0 0.1 0.0039 17.6 0.1 1.7 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 EWM21719.1 - 0.013 14.4 0.1 0.09 11.7 0.1 2.0 1 1 0 1 1 1 0 L-fucokinase W2 PF02020.18 EWM21719.1 - 0.033 14.3 0.3 0.033 14.3 0.3 2.3 2 0 0 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon CTP_transf_3 PF02348.19 EWM21719.1 - 0.075 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase Sortilin-Vps10 PF15902.5 EWM21720.1 - 1.1e-05 24.4 0.9 1.3e-05 24.2 0.9 1.1 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, BNR_3 PF13859.6 EWM21720.1 - 0.002 17.5 6.8 0.17 11.1 0.8 2.0 1 1 1 2 2 2 2 BNR repeat-like domain BNR_6 PF15899.5 EWM21720.1 - 0.008 16.1 0.0 7.3 7.0 0.0 3.0 2 0 0 2 2 2 2 BNR-Asp box repeat BNR PF02012.20 EWM21720.1 - 0.012 15.4 12.0 0.18 12.0 0.3 3.2 3 0 0 3 3 3 0 BNR/Asp-box repeat PSII_BNR PF14870.6 EWM21720.1 - 0.082 12.2 6.5 0.21 10.8 6.5 1.6 1 1 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 zf-UBP PF02148.19 EWM21721.1 - 2.3e-07 31.0 1.2 4.7e-07 30.0 1.2 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH PF00443.29 EWM21721.1 - 3.1e-07 30.2 0.0 3.6e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-RING_4 PF14570.6 EWM21721.1 - 0.33 10.8 5.6 0.38 10.6 0.5 2.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Trypsin PF00089.26 EWM21724.1 - 6.4e-52 176.6 0.1 1.7e-51 175.1 0.1 1.7 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 EWM21724.1 - 6.3e-06 27.2 0.2 1.8e-05 25.7 0.2 1.8 1 0 0 1 1 1 1 Trypsin-like peptidase domain FemAB_like PF04339.12 EWM21724.1 - 0.052 12.7 0.0 0.083 12.0 0.0 1.2 1 0 0 1 1 1 0 Peptidogalycan biosysnthesis/recognition DUF316 PF03761.15 EWM21724.1 - 0.11 12.1 0.0 4.5 6.7 0.0 2.2 2 0 0 2 2 2 0 Chymotrypsin family Peptidase-S1 Rab3-GTPase_cat PF13890.6 EWM21725.1 - 1.7e-21 76.6 0.1 5.6e-21 74.9 0.0 1.9 2 0 0 2 2 2 1 Rab3 GTPase-activating protein catalytic subunit DUF1027 PF06265.11 EWM21726.1 - 0.18 11.8 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) DEAD PF00270.29 EWM21727.1 - 3.1e-12 46.6 0.0 3.5e-12 46.4 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EWM21727.1 - 0.00028 20.9 0.0 0.0003 20.8 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Sm_multidrug_ex PF06695.11 EWM21730.1 - 1.1e-12 48.6 0.3 5.5e-07 30.3 0.1 2.6 2 0 0 2 2 2 2 Putative small multi-drug export protein NCD2 PF04905.13 EWM21730.1 - 0.15 12.0 0.3 0.36 10.8 0.3 1.6 1 0 0 1 1 1 0 NAB conserved region 2 (NCD2) Tim17 PF02466.19 EWM21731.1 - 4.2e-06 27.1 8.2 4.2e-06 27.1 8.2 1.6 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Transketolase_C PF02780.20 EWM21732.1 - 3.1e-34 117.5 0.0 4.5e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 EWM21732.1 - 8.9e-17 61.3 0.0 1.4e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain PFOR_II PF17147.4 EWM21732.1 - 0.039 14.3 0.0 0.058 13.7 0.0 1.3 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II Hist_deacetyl PF00850.19 EWM21734.1 - 1.2e-79 268.0 0.1 2.1e-79 267.2 0.0 1.4 2 0 0 2 2 2 1 Histone deacetylase domain ThiF PF00899.21 EWM21735.1 - 3.3e-48 164.2 0.0 4.9e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family Herpes_TAF50 PF03326.13 EWM21735.1 - 0.0016 17.2 0.4 0.0023 16.7 0.4 1.1 1 0 0 1 1 1 1 Herpesvirus transcription activation factor (transactivator) NAD_binding_7 PF13241.6 EWM21735.1 - 0.034 14.6 0.0 0.089 13.2 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 EWM21735.1 - 0.047 12.9 0.9 0.07 12.4 0.9 1.2 1 0 0 1 1 1 0 FAD binding domain Sacchrp_dh_NADP PF03435.18 EWM21735.1 - 0.055 13.7 0.1 1.9 8.7 0.0 2.6 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 EWM21735.1 - 0.17 11.2 0.0 0.44 9.9 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EWM21735.1 - 0.18 11.4 0.0 0.43 10.1 0.0 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Peptidase_C1 PF00112.23 EWM21736.1 - 2.1e-60 204.6 1.6 2.8e-60 204.1 1.6 1.2 1 0 0 1 1 1 1 Papain family cysteine protease E1_DerP2_DerF2 PF02221.15 EWM21736.1 - 1.3e-11 45.1 0.0 3.2e-11 43.8 0.0 1.7 2 0 0 2 2 2 1 ML domain Inhibitor_I29 PF08246.12 EWM21736.1 - 1.5e-11 44.5 0.0 2.4e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EWM21736.1 - 0.0014 17.5 0.7 0.01 14.7 0.4 2.1 2 0 0 2 2 2 1 Peptidase C1-like family GTP1_OBG PF01018.22 EWM21738.1 - 1.3e-34 119.0 11.2 7.9e-33 113.2 8.9 2.3 2 0 0 2 2 2 2 GTP1/OBG BUD22 PF09073.10 EWM21738.1 - 3 7.1 6.5 4.1 6.7 6.5 1.1 1 0 0 1 1 1 0 BUD22 Thioredoxin PF00085.20 EWM21739.1 - 1.4e-18 66.8 0.0 1.9e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EWM21739.1 - 0.0012 19.2 0.0 0.014 15.7 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EWM21739.1 - 0.0032 17.9 0.1 0.099 13.1 0.1 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_6 PF13848.6 EWM21739.1 - 0.0052 16.7 0.0 0.0079 16.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain TPR_19 PF14559.6 EWM21739.1 - 0.016 15.7 1.2 0.03 14.9 0.8 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat Thioredoxin_7 PF13899.6 EWM21739.1 - 0.078 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like OST3_OST6 PF04756.13 EWM21739.1 - 0.18 11.1 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family TPR_12 PF13424.6 EWM21739.1 - 0.54 10.6 2.9 0.64 10.3 1.4 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Thioredoxin PF00085.20 EWM21740.1 - 1.4e-18 66.8 0.0 1.9e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EWM21740.1 - 0.0012 19.2 0.0 0.014 15.7 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EWM21740.1 - 0.0032 17.9 0.1 0.099 13.1 0.1 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_6 PF13848.6 EWM21740.1 - 0.0052 16.7 0.0 0.0079 16.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain TPR_19 PF14559.6 EWM21740.1 - 0.016 15.7 1.2 0.03 14.9 0.8 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat Thioredoxin_7 PF13899.6 EWM21740.1 - 0.078 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like OST3_OST6 PF04756.13 EWM21740.1 - 0.18 11.1 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family TPR_12 PF13424.6 EWM21740.1 - 0.54 10.6 2.9 0.64 10.3 1.4 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat GerE PF00196.19 EWM21742.1 - 3.4e-09 36.1 0.0 5.2e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family KORA PF16509.5 EWM21742.1 - 0.17 12.2 0.0 0.57 10.5 0.0 1.8 2 0 0 2 2 2 0 TrfB plasmid transcriptional repressor YlmH_RBD PF17774.1 EWM21747.1 - 2.2e-11 43.9 0.0 3.7e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Putative RNA-binding domain in YlmH YlmH_RBD PF17774.1 EWM21748.1 - 0.024 14.9 0.0 0.045 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative RNA-binding domain in YlmH Ribosomal_L26 PF16906.5 EWM21749.1 - 4e-24 84.9 1.2 9.4e-24 83.7 1.0 1.7 2 0 0 2 2 2 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 EWM21749.1 - 0.0077 16.2 6.4 0.018 15.0 6.4 1.6 1 0 0 1 1 1 1 KOW motif ARD PF03079.14 EWM21750.1 - 8.2e-56 188.5 0.4 9.7e-56 188.3 0.4 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 EWM21750.1 - 2.5e-08 33.5 0.0 6e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EWM21750.1 - 3.7e-06 26.9 0.0 5.2e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 EWM21750.1 - 0.0033 17.1 0.0 0.016 14.8 0.0 1.9 2 0 0 2 2 2 1 Cupin Ni_hydr_CYTB PF01292.20 EWM21751.1 - 1.9e-11 43.9 3.8 2.6e-11 43.4 3.8 1.2 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 FMO-like PF00743.19 EWM21751.1 - 0.033 12.6 0.0 0.044 12.2 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like ARL6IP6 PF15062.6 EWM21751.1 - 0.14 12.3 0.3 3.4 7.8 0.1 2.3 1 1 1 2 2 2 0 Haemopoietic lineage transmembrane helix ACPS PF01648.20 EWM21752.1 - 1.8e-12 47.4 0.0 3.9e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily PEX-1N PF09262.11 EWM21754.1 - 5.3e-23 81.2 0.3 9.9e-23 80.4 0.3 1.5 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal PNK3P PF08645.11 EWM21756.1 - 3.4e-44 150.4 0.0 4.5e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase ADH_zinc_N PF00107.26 EWM21757.1 - 1.3e-20 73.7 0.1 2.7e-20 72.7 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EWM21757.1 - 9.7e-18 64.1 0.0 3.5e-10 39.8 0.0 2.5 2 0 0 2 2 2 2 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EWM21757.1 - 2.9e-09 38.1 0.0 6.3e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CS PF04969.16 EWM21757.1 - 6.5e-09 36.7 0.0 1.1e-08 35.9 0.0 1.4 1 0 0 1 1 1 1 CS domain Nas2_N PF18265.1 EWM21758.1 - 1.8e-21 75.8 0.0 3.2e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 EWM21758.1 - 2.2e-08 33.8 0.4 4.7e-08 32.8 0.4 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EWM21758.1 - 8e-06 26.1 0.1 1.4e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EWM21758.1 - 4.6e-05 23.7 0.0 9.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain kleA_kleC PF17383.2 EWM21758.1 - 0.068 13.5 0.4 0.25 11.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A AAA PF00004.29 EWM21759.1 - 3.7e-41 140.6 0.0 7.9e-41 139.6 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EWM21759.1 - 1.4e-05 25.6 1.6 0.00013 22.4 0.2 2.7 2 2 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EWM21759.1 - 0.0003 20.6 0.0 0.0007 19.4 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EWM21759.1 - 0.0019 18.5 0.0 0.26 11.5 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA_lid_3 PF17862.1 EWM21759.1 - 0.002 17.9 4.6 0.24 11.2 0.4 3.1 3 0 0 3 3 2 2 AAA+ lid domain AAA_25 PF13481.6 EWM21759.1 - 0.0055 16.3 0.2 2.8 7.5 0.1 2.5 1 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EWM21759.1 - 0.0059 16.8 0.0 0.01 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 EWM21759.1 - 0.0065 15.7 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 EWM21759.1 - 0.036 14.1 0.1 0.083 12.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 EWM21759.1 - 0.045 13.7 0.0 0.071 13.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_2 PF07724.14 EWM21759.1 - 0.055 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 EWM21759.1 - 0.077 12.4 0.1 0.18 11.2 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 EWM21759.1 - 0.14 12.1 0.2 0.8 9.6 0.1 2.2 3 0 0 3 3 3 0 NACHT domain AAA_18 PF13238.6 EWM21759.1 - 0.19 12.2 0.0 0.35 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EWM21759.1 - 0.2 11.4 0.1 0.38 10.5 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 EWM21759.1 - 0.2 11.6 0.0 0.35 10.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EWM21759.1 - 0.22 12.0 0.0 0.4 11.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase TB2_DP1_HVA22 PF03134.19 EWM21760.1 - 4.9e-12 45.6 0.4 7.8e-12 45.0 0.4 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family C2 PF00168.30 EWM21760.1 - 0.0085 16.4 0.0 0.014 15.6 0.0 1.3 1 0 0 1 1 1 1 C2 domain Pkinase PF00069.25 EWM21761.1 - 1.4e-75 254.1 0.0 1.4e-75 254.1 0.0 3.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM21761.1 - 1.3e-39 136.1 0.0 1.3e-39 136.1 0.0 3.3 3 1 0 3 3 3 1 Protein tyrosine kinase KA1 PF02149.19 EWM21761.1 - 2.4e-06 27.2 0.2 8.4e-06 25.5 0.0 1.9 2 0 0 2 2 2 1 Kinase associated domain 1 AdenylateSensor PF16579.5 EWM21761.1 - 2.7e-05 24.6 0.1 2.7e-05 24.6 0.1 4.9 4 1 1 5 5 5 2 Adenylate sensor of SNF1-like protein kinase CDC45 PF02724.14 EWM21761.1 - 3.9 5.6 46.1 5.7 5.1 46.1 1.2 1 0 0 1 1 1 0 CDC45-like protein MFS_1 PF07690.16 EWM21762.1 - 0.052 12.5 0.6 0.06 12.3 0.6 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily Ac76 PF05814.11 EWM21762.1 - 0.18 11.8 0.3 7.3 6.7 0.7 2.1 2 0 0 2 2 2 0 Orf76 (Ac76) FixQ PF05545.11 EWM21762.1 - 0.97 9.5 0.0 0.97 9.5 0.0 2.0 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ MFS_1 PF07690.16 EWM21763.1 - 0.045 12.7 0.6 0.051 12.5 0.6 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily Ac76 PF05814.11 EWM21763.1 - 0.16 12.0 0.3 6.7 6.8 0.7 2.1 2 0 0 2 2 2 0 Orf76 (Ac76) FixQ PF05545.11 EWM21763.1 - 0.88 9.6 0.0 0.88 9.6 0.0 2.0 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ MFS_1 PF07690.16 EWM21764.1 - 0.045 12.7 0.6 0.051 12.5 0.6 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily Ac76 PF05814.11 EWM21764.1 - 0.16 12.0 0.3 6.7 6.8 0.7 2.1 2 0 0 2 2 2 0 Orf76 (Ac76) FixQ PF05545.11 EWM21764.1 - 0.88 9.6 0.0 0.88 9.6 0.0 2.0 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF1295 PF06966.12 EWM21765.1 - 1.7e-36 125.9 18.1 2.9e-35 121.9 18.1 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Cpn60_TCP1 PF00118.24 EWM21766.1 - 1.2e-151 505.8 11.2 1.4e-151 505.5 11.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.24 EWM21767.1 - 2.9e-98 329.6 3.7 3.4e-98 329.4 3.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TRAM_LAG1_CLN8 PF03798.16 EWM21768.1 - 1.2e-05 25.1 16.8 1.2e-05 25.1 16.8 2.3 1 1 1 2 2 2 1 TLC domain UPF0093 PF03653.13 EWM21768.1 - 0.51 10.6 7.0 5.9 7.1 0.7 2.9 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0093) GCP_C_terminal PF04130.13 EWM21770.1 - 4.8e-06 26.3 0.0 6.6e-06 25.8 0.0 1.3 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal PRIMA1 PF16101.5 EWM21770.1 - 0.86 9.6 3.3 1.6 8.8 3.3 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF2203 PF09969.9 EWM21771.1 - 0.085 13.6 0.0 0.13 12.9 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DDHD PF02862.17 EWM21771.1 - 0.1 12.7 9.7 0.13 12.4 9.7 1.2 1 0 0 1 1 1 0 DDHD domain Apt1 PF10351.9 EWM21771.1 - 5.1 5.8 16.3 7.3 5.3 16.3 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 EWM21771.1 - 9.4 4.7 18.0 10 4.5 18.0 1.0 1 0 0 1 1 1 0 Macoilin family MatE PF01554.18 EWM21773.1 - 1.8e-15 57.0 23.1 9.6e-15 54.6 3.2 4.6 3 2 0 3 3 3 3 MatE Polysacc_synt_C PF14667.6 EWM21773.1 - 2.3e-09 37.5 6.8 2.3e-09 37.5 6.8 3.4 3 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain MurJ PF03023.14 EWM21773.1 - 0.0012 17.6 3.3 0.0012 17.6 3.3 2.1 2 1 0 2 2 2 1 Lipid II flippase MurJ TisB_toxin PF13939.6 EWM21774.1 - 0.064 13.1 1.9 0.11 12.3 1.9 1.3 1 0 0 1 1 1 0 Toxin TisB, type I toxin-antitoxin system Menin PF05053.13 EWM21775.1 - 0.022 13.2 0.2 0.033 12.6 0.2 1.2 1 0 0 1 1 1 0 Menin Ion_trans PF00520.31 EWM21776.1 - 2.3e-38 131.8 22.7 3.7e-22 78.7 3.6 2.2 2 0 0 2 2 2 2 Ion transport protein HemY_N PF07219.13 EWM21776.1 - 0.046 13.9 2.0 0.37 11.0 0.1 3.4 3 0 0 3 3 3 0 HemY protein N-terminus DUF1774 PF08611.10 EWM21776.1 - 0.11 12.9 0.1 0.11 12.9 0.1 3.2 3 0 0 3 3 3 0 Fungal protein of unknown function (DUF1774) DUF179 PF02622.15 EWM21777.1 - 1.2e-13 51.4 0.0 1.8e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 DIX PF00778.17 EWM21779.1 - 5e-11 42.3 0.0 6.7e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 DIX domain WAP PF00095.21 EWM21780.1 - 0.048 14.1 9.6 0.14 12.6 9.6 1.8 1 1 0 1 1 1 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' CDO_I PF05995.12 EWM21781.1 - 2.6e-25 88.7 0.0 4.9e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 EWM21781.1 - 0.028 13.9 0.0 0.077 12.4 0.0 1.7 1 0 0 1 1 1 0 PCO_ADO Phosducin PF02114.16 EWM21782.1 - 9.8e-20 70.6 0.0 4.1e-19 68.5 0.0 1.8 1 1 0 1 1 1 1 Phosducin Lipase_GDSL_2 PF13472.6 EWM21783.1 - 0.018 15.4 0.0 0.16 12.4 0.0 2.5 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Piezo_RRas_bdg PF12166.8 EWM21785.1 - 1.3e-81 275.1 0.0 2.7e-81 274.0 0.0 1.5 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain PIEZO PF15917.5 EWM21785.1 - 0.18 11.3 0.1 0.36 10.3 0.1 1.4 1 0 0 1 1 1 0 Piezo F-box PF00646.33 EWM21786.1 - 4.2e-07 29.7 0.2 9.8e-07 28.5 0.2 1.6 1 0 0 1 1 1 1 F-box domain ZZ PF00569.17 EWM21786.1 - 2.7e-06 27.1 11.5 6.5e-06 25.9 11.5 1.6 1 0 0 1 1 1 1 Zinc finger, ZZ type F-box-like PF12937.7 EWM21786.1 - 2.2e-05 24.2 1.3 5.1e-05 23.1 1.3 1.6 1 0 0 1 1 1 1 F-box-like MATH PF00917.26 EWM21786.1 - 0.11 12.7 0.0 1.1 9.4 0.0 2.1 2 0 0 2 2 2 0 MATH domain Aminotran_1_2 PF00155.21 EWM21787.1 - 2.5e-47 161.8 0.0 3.3e-47 161.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EWM21787.1 - 2.9e-07 30.1 0.1 4.3e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EWM21787.1 - 0.0018 17.7 0.0 0.003 16.9 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family OKR_DC_1 PF01276.20 EWM21787.1 - 0.0067 15.2 0.0 0.016 14.0 0.0 1.5 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.20 EWM21787.1 - 0.014 13.9 0.0 0.024 13.2 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Dynactin_p62 PF05502.13 EWM21790.1 - 3.4e-15 55.8 7.9 2.3e-14 53.0 2.7 3.0 3 0 0 3 3 3 1 Dynactin p62 family KdpD PF02702.17 EWM21790.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain Elf1 PF05129.13 EWM21790.1 - 0.14 12.3 3.1 0.079 13.0 0.9 1.7 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-MYST PF17772.1 EWM21790.1 - 0.18 11.4 1.6 0.74 9.5 1.4 2.1 2 0 0 2 2 2 0 MYST family zinc finger domain Fer4_4 PF12800.7 EWM21790.1 - 6.7 7.5 8.7 2.4 8.9 3.9 2.8 2 0 0 2 2 2 0 4Fe-4S binding domain HSP70 PF00012.20 EWM21791.1 - 2.1e-102 343.3 0.0 3.4e-84 283.1 0.0 2.3 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EWM21791.1 - 4e-15 55.5 0.9 9.9e-11 41.0 0.0 3.1 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.16 EWM21791.1 - 6.4e-05 22.8 0.0 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain UDPGP PF01704.18 EWM21792.1 - 6.3e-120 400.6 0.0 7.8e-120 400.3 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PGM_PMM_I PF02878.16 EWM21792.1 - 4e-28 97.8 0.0 7.5e-28 97.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EWM21792.1 - 2.3e-24 85.8 0.0 4.9e-24 84.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EWM21792.1 - 3.3e-08 34.1 0.3 1.2e-07 32.2 0.3 2.0 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EWM21792.1 - 0.00028 21.0 0.0 0.00091 19.4 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain LSM PF01423.22 EWM21793.1 - 8.4e-18 63.8 0.0 1.1e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EWM21793.1 - 0.0031 17.6 0.0 0.0047 17.0 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Rdx PF10262.9 EWM21794.1 - 5.5e-31 106.6 0.1 8.5e-31 106.0 0.1 1.3 1 0 0 1 1 1 1 Rdx family Thymidylat_synt PF00303.19 EWM21795.1 - 3.3e-116 387.1 0.0 8.1e-116 385.8 0.0 1.6 2 0 0 2 2 2 1 Thymidylate synthase DHFR_1 PF00186.19 EWM21795.1 - 1.7e-33 115.6 0.0 2.8e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 Dihydrofolate reductase Thymidylate_kin PF02223.17 EWM21796.1 - 1.4e-44 152.0 0.0 1.8e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_22 PF13401.6 EWM21796.1 - 0.12 12.7 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EWM21796.1 - 0.19 11.8 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Diedel PF13164.6 EWM21797.1 - 0.032 14.7 2.1 0.032 14.7 2.1 3.4 3 1 0 4 4 4 0 Diedel DUF3119 PF11317.8 EWM21798.1 - 3.7e-37 127.4 0.0 5.5e-37 126.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3119) NAD_binding_10 PF13460.6 EWM21799.1 - 9.4e-07 28.9 0.0 1.6e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding SfsA PF03749.13 EWM21800.1 - 2.2e-20 72.9 0.0 1.2e-18 67.4 0.0 2.5 1 1 0 1 1 1 1 Sugar fermentation stimulation protein RE domain SfsA_N PF17746.1 EWM21800.1 - 0.019 15.1 0.1 0.058 13.6 0.0 1.9 2 0 0 2 2 2 0 SfsA N-terminal OB domain KIAA1328 PF15369.6 EWM21800.1 - 2.3 8.0 5.5 3.4 7.4 5.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 2-oxoacid_dh PF00198.23 EWM21801.1 - 6.4e-71 238.5 0.0 8.4e-71 238.1 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EWM21801.1 - 3e-13 49.4 0.7 7e-13 48.2 0.3 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 EWM21801.1 - 7e-10 39.1 1.2 1.8e-08 34.6 0.0 3.0 3 0 0 3 3 3 1 e3 binding domain HlyD_3 PF13437.6 EWM21801.1 - 0.015 16.0 0.0 0.91 10.3 0.0 2.7 1 1 1 2 2 2 0 HlyD family secretion protein Abhydrolase_2 PF02230.16 EWM21802.1 - 1.2e-44 152.7 0.0 1.6e-44 152.3 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EWM21802.1 - 7.3e-06 26.7 0.7 1e-05 26.2 0.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EWM21802.1 - 0.0005 19.8 0.0 0.0026 17.5 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Cutinase PF01083.22 EWM21802.1 - 0.0062 16.5 0.0 0.0096 15.9 0.0 1.3 1 0 0 1 1 1 1 Cutinase Abhydrolase_3 PF07859.13 EWM21802.1 - 0.0087 15.9 0.1 0.013 15.4 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EWM21802.1 - 0.011 15.1 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF5323 PF17257.2 EWM21803.1 - 0.023 14.6 2.1 0.034 14.0 1.5 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5323) H_PPase PF03030.16 EWM21806.1 - 3.2e-239 795.9 32.6 3.7e-239 795.7 32.6 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase DUF5542 PF17696.1 EWM21806.1 - 0.11 12.6 0.0 0.36 11.0 0.0 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5542) DUF2275 PF10039.9 EWM21806.1 - 0.42 10.7 1.1 1.1 9.4 0.1 2.1 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2275) WD40 PF00400.32 EWM21807.1 - 8.9e-15 54.8 1.8 0.0009 20.0 0.1 7.0 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM21807.1 - 5.2e-07 29.9 0.0 11 6.4 0.0 5.7 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_M17 PF00883.21 EWM21808.1 - 2e-119 398.5 0.5 2.6e-119 398.1 0.5 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 EWM21808.1 - 1.2e-16 60.8 0.4 1.2e-16 60.8 0.4 3.5 4 0 0 4 4 4 1 Cytosol aminopeptidase family, N-terminal domain LCAT PF02450.15 EWM21809.1 - 2e-80 270.9 0.0 2.5e-79 267.3 0.0 2.0 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.14 EWM21809.1 - 0.01 15.4 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) ELO PF01151.18 EWM21810.1 - 2.6e-59 200.8 10.2 3.2e-59 200.5 10.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family SelK_SelG PF10961.8 EWM21810.1 - 7.9 7.2 12.0 0.15 12.7 4.6 2.0 2 0 0 2 2 2 0 Selenoprotein SelK_SelG 2OG-FeII_Oxy_2 PF13532.6 EWM21811.1 - 0.00027 21.2 0.0 0.00051 20.3 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TAXi_N PF14543.6 EWM21812.1 - 3e-23 83.0 0.1 4.1e-23 82.5 0.1 1.2 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.23 EWM21812.1 - 3.2e-08 33.4 0.0 1.7e-07 31.0 0.0 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Nup188_C PF18378.1 EWM21814.1 - 0.0058 15.5 0.2 0.0074 15.2 0.2 1.1 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain PRIMA1 PF16101.5 EWM21814.1 - 0.35 10.9 2.4 0.54 10.3 2.4 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Pkinase PF00069.25 EWM21815.1 - 5e-14 52.3 0.0 4.9e-13 49.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM21815.1 - 0.028 13.7 0.0 0.038 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase adh_short PF00106.25 EWM21817.1 - 1.1e-42 145.7 0.2 1.5e-42 145.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EWM21817.1 - 3.4e-28 98.8 0.1 4.8e-28 98.3 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM21817.1 - 1.5e-10 41.2 0.2 3.1e-10 40.2 0.2 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EWM21817.1 - 0.001 19.0 0.1 0.0018 18.2 0.1 1.5 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EWM21817.1 - 0.023 14.3 0.4 0.037 13.6 0.4 1.3 1 0 0 1 1 1 0 NmrA-like family tRNA-synt_2 PF00152.20 EWM21818.1 - 3.8e-72 243.0 0.0 5.1e-72 242.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EWM21818.1 - 3.2e-05 23.8 0.0 6.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EWM21818.1 - 0.0023 17.5 0.1 0.39 10.2 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti_2 PF13742.6 EWM21818.1 - 0.17 12.1 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain 5_nucleotid PF05761.14 EWM21819.1 - 2.8e-133 445.2 0.0 3.2e-133 445.0 0.0 1.0 1 0 0 1 1 1 1 5' nucleotidase family Hydrolase_like PF13242.6 EWM21819.1 - 0.038 14.0 0.0 0.095 12.8 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like Fe-S_biosyn PF01521.20 EWM21820.1 - 7.2e-16 58.4 0.0 1e-15 57.9 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Pkinase PF00069.25 EWM21821.1 - 4.8e-33 114.7 0.0 8.6e-33 113.8 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM21821.1 - 4.7e-19 68.7 0.0 6.7e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EWM21821.1 - 0.034 14.0 0.1 0.086 12.7 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EWM21821.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RRM_1 PF00076.22 EWM21822.1 - 3.9e-35 119.5 0.0 9.4e-17 60.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EWM21822.1 - 4.1e-12 46.1 0.2 1.3e-05 25.3 0.1 2.7 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EWM21822.1 - 5.3e-05 23.1 0.1 0.021 14.8 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif MtrH PF02007.18 EWM21822.1 - 0.04 13.0 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase MtrH subunit PHM7_cyt PF14703.6 EWM21822.1 - 0.049 13.9 0.0 1.7 8.9 0.0 2.5 2 2 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Pkinase PF00069.25 EWM21823.1 - 1.1e-64 218.3 0.0 1.5e-64 217.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM21823.1 - 9.9e-30 103.7 0.0 1.4e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 EWM21823.1 - 5.6e-16 56.8 4.0 0.00097 18.5 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EWM21823.1 - 9.5e-14 50.1 0.5 0.0019 18.0 0.0 4.0 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 EWM21823.1 - 4.2e-12 46.3 3.2 2.7e-08 34.1 0.8 3.5 2 2 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EWM21823.1 - 7.1e-10 38.6 1.9 0.045 13.6 0.0 3.6 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EWM21823.1 - 1.4e-08 33.8 7.4 0.0013 18.1 0.1 4.3 4 0 0 4 4 4 2 EF hand Kinase-like PF14531.6 EWM21823.1 - 3.3e-05 23.3 0.0 0.0072 15.7 0.0 2.4 1 1 1 2 2 2 2 Kinase-like SPARC_Ca_bdg PF10591.9 EWM21823.1 - 0.0087 16.4 0.1 1.4 9.3 0.0 2.6 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region APH PF01636.23 EWM21823.1 - 0.012 15.5 0.0 0.63 9.9 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family EF-hand_4 PF12763.7 EWM21823.1 - 0.071 13.1 0.1 2.7 8.0 0.0 2.6 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand PACT_coil_coil PF10495.9 EWM21823.1 - 0.1 13.2 0.3 0.66 10.6 0.1 2.4 2 0 0 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein ABC1 PF03109.16 EWM21823.1 - 0.1 12.8 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 ABC1 family Sod_Fe_C PF02777.18 EWM21824.1 - 2.5e-35 120.7 1.3 8.5e-35 119.0 0.0 2.1 2 1 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EWM21824.1 - 2.6e-28 98.3 0.5 4.3e-28 97.6 0.5 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Beta_elim_lyase PF01212.21 EWM21824.1 - 0.025 13.8 0.0 0.03 13.6 0.0 1.1 1 0 0 1 1 1 0 Beta-eliminating lyase Ras PF00071.22 EWM21825.1 - 6.8e-56 188.3 0.0 8e-56 188.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EWM21825.1 - 5.4e-33 113.8 0.0 8e-33 113.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EWM21825.1 - 6.7e-12 45.2 0.0 7.7e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EWM21825.1 - 4.4e-06 26.7 0.0 6.2e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EWM21825.1 - 0.00097 18.6 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EWM21825.1 - 0.0031 17.0 0.0 0.0039 16.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EWM21825.1 - 0.005 16.4 0.0 0.053 13.1 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EWM21825.1 - 0.0059 16.5 0.0 0.025 14.5 0.0 2.0 2 1 1 3 3 3 1 RsgA GTPase AAA_7 PF12775.7 EWM21825.1 - 0.031 13.8 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 EWM21825.1 - 0.045 13.0 0.0 0.08 12.2 0.0 1.4 2 0 0 2 2 2 0 Septin AAA_22 PF13401.6 EWM21825.1 - 0.051 13.8 0.0 0.084 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EWM21825.1 - 0.063 13.2 0.0 0.098 12.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DAP3 PF10236.9 EWM21825.1 - 0.082 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 cobW PF02492.19 EWM21825.1 - 0.1 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Glyco_hydro_75 PF07335.11 EWM21825.1 - 0.12 12.7 0.0 0.52 10.6 0.0 1.8 1 1 1 2 2 2 0 Fungal chitosanase of glycosyl hydrolase group 75 AAA_16 PF13191.6 EWM21825.1 - 0.12 12.7 0.0 0.2 12.0 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Peptidase_M76 PF09768.9 EWM21826.1 - 2e-50 170.9 6.5 2.3e-50 170.7 6.5 1.0 1 0 0 1 1 1 1 Peptidase M76 family Peptidase_M91 PF14891.6 EWM21826.1 - 0.1 12.9 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Effector protein RIC1 PF07064.13 EWM21827.1 - 1.4e-09 37.7 0.1 3.4e-09 36.5 0.0 1.6 2 0 0 2 2 2 1 RIC1 ANAPC4_WD40 PF12894.7 EWM21827.1 - 9.8e-06 25.8 0.1 0.096 13.0 0.0 5.2 4 2 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EWM21827.1 - 0.0028 18.5 0.2 3 8.9 0.0 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat GATase_6 PF13522.6 EWM21828.1 - 4e-14 53.0 0.0 7.3e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EWM21828.1 - 3.2e-13 49.7 0.0 5.1e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 EWM21828.1 - 1.2e-05 24.9 0.0 2.5e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 EWM21828.1 - 5e-05 22.3 0.0 0.0001 21.3 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferases class-II Methyltransf_16 PF10294.9 EWM21829.1 - 1.5e-16 60.7 0.1 1.2e-14 54.4 0.1 2.5 1 1 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 EWM21829.1 - 3.5e-06 26.7 0.1 6.1e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EWM21829.1 - 0.0033 16.8 0.1 0.0056 16.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DUF1610 PF07754.11 EWM21829.1 - 0.065 13.2 4.5 3.1 7.9 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) Cons_hypoth95 PF03602.15 EWM21829.1 - 0.09 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 EWM21829.1 - 0.1 13.3 0.1 0.27 12.0 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 EWM21829.1 - 0.18 11.1 0.0 0.34 10.2 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Cyclin_N PF00134.23 EWM21830.1 - 5.4e-35 119.9 0.4 1.1e-34 118.9 0.4 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EWM21830.1 - 2.5e-21 76.0 0.3 6.3e-21 74.7 0.0 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain Baculo_p48 PF04878.13 EWM21830.1 - 0.0069 15.4 0.9 0.01 14.8 0.9 1.2 1 0 0 1 1 1 1 Baculovirus P48 protein YejG PF13989.6 EWM21830.1 - 0.05 14.1 0.2 0.087 13.3 0.2 1.4 1 0 0 1 1 1 0 YejG-like protein ABC2_membrane PF01061.24 EWM21831.1 - 4.3e-39 134.1 20.2 4.3e-39 134.1 20.2 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 EWM21831.1 - 9.9e-22 77.9 0.0 2e-21 77.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EWM21831.1 - 6.1e-11 42.0 19.7 9.4e-11 41.4 19.7 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_29 PF13555.6 EWM21831.1 - 0.0009 18.9 0.3 0.0022 17.7 0.3 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EWM21831.1 - 0.0051 16.7 0.3 0.0099 15.8 0.3 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 EWM21831.1 - 0.024 14.5 0.0 5.2 6.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EWM21831.1 - 0.04 14.2 0.1 0.44 10.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EWM21831.1 - 0.11 12.8 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Zip PF02535.22 EWM21832.1 - 7.1e-34 117.5 16.8 3.8e-33 115.1 16.8 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter DUF4199 PF13858.6 EWM21832.1 - 1.4 9.3 9.4 0.27 11.6 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Peptidase_U4 PF03419.13 EWM21832.1 - 3.2 7.0 8.2 0.46 9.7 0.9 2.1 2 0 0 2 2 2 0 Sporulation factor SpoIIGA RHD3 PF05879.12 EWM21833.1 - 6.3e-38 130.4 0.0 1.1e-37 129.6 0.0 1.3 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 EWM21833.1 - 0.012 15.6 0.3 0.45 10.6 0.1 2.9 2 1 1 3 3 3 0 50S ribosome-binding GTPase AAA_16 PF13191.6 EWM21833.1 - 0.054 13.9 3.3 1.2 9.5 0.7 3.5 2 1 1 3 3 3 0 AAA ATPase domain NB-ARC PF00931.22 EWM21833.1 - 0.07 12.3 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain PrmA PF06325.13 EWM21834.1 - 6.5e-52 176.8 0.0 3.3e-51 174.4 0.0 1.8 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EWM21834.1 - 2.1e-05 24.4 0.1 4.3e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EWM21834.1 - 0.0016 18.0 0.1 0.0028 17.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EWM21834.1 - 0.022 15.5 0.1 0.047 14.4 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain Rib PF08428.10 EWM21834.1 - 0.067 13.2 0.2 0.17 11.9 0.0 1.7 2 0 0 2 2 2 0 Rib/alpha-like repeat Methyltransf_23 PF13489.6 EWM21834.1 - 0.077 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain SIS PF01380.22 EWM21835.1 - 2.4e-22 79.2 0.7 6.9e-22 77.7 0.4 1.9 2 0 0 2 2 2 1 SIS domain PfkB PF00294.24 EWM21835.1 - 7.7e-21 74.7 1.0 7.7e-21 74.7 1.0 1.8 2 0 0 2 2 2 1 pfkB family carbohydrate kinase SIS_2 PF13580.6 EWM21835.1 - 1.7e-07 31.3 4.2 4.2e-05 23.6 0.0 3.3 2 1 1 3 3 3 2 SIS domain DUF2529 PF10740.9 EWM21835.1 - 0.0034 17.0 0.1 0.018 14.7 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF2529) Ham1p_like PF01725.16 EWM21836.1 - 1.1e-52 178.7 0.0 1.3e-52 178.5 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Methyltransf_21 PF05050.12 EWM21837.1 - 9.1e-15 55.1 0.0 1.6e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain Met_10 PF02475.16 EWM21837.1 - 0.1 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_21 PF05050.12 EWM21838.1 - 1.3e-14 54.6 0.0 2.7e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase FkbM domain Glyco_transf_28 PF03033.20 EWM21838.1 - 0.0042 17.1 0.0 0.009 16.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Met_10 PF02475.16 EWM21838.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Bromodomain PF00439.25 EWM21839.1 - 8.2e-22 77.1 0.0 3.4e-10 39.9 0.0 2.3 2 0 0 2 2 2 2 Bromodomain GDP_Man_Dehyd PF16363.5 EWM21840.1 - 3.9e-59 200.7 0.0 4.5e-59 200.5 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EWM21840.1 - 1.5e-50 172.0 0.0 2e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EWM21840.1 - 2.1e-15 56.6 0.0 6.1e-14 51.8 0.0 2.6 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EWM21840.1 - 5e-12 45.4 0.0 1.2e-11 44.2 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EWM21840.1 - 2.8e-10 39.8 0.0 4.4e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EWM21840.1 - 1.6e-06 27.5 0.0 0.00022 20.5 0.0 2.2 1 1 0 2 2 2 2 Male sterility protein KR PF08659.10 EWM21840.1 - 5.7e-06 26.3 0.0 1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 EWM21840.1 - 7.4e-05 22.3 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 EWM21840.1 - 0.0014 18.6 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Pyr_redox_2 PF07992.14 EWM21840.1 - 0.16 11.2 0.1 0.25 10.5 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 EWM21840.1 - 0.17 11.4 0.1 0.28 10.8 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trns_repr_metal PF02583.17 EWM21840.1 - 0.17 12.2 0.0 0.43 11.0 0.0 1.6 1 0 0 1 1 1 0 Metal-sensitive transcriptional repressor Abhydrolase_1 PF00561.20 EWM21842.1 - 0.00034 20.4 0.0 0.0057 16.3 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EWM21842.1 - 0.0065 15.8 0.0 0.029 13.6 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EWM21842.1 - 0.031 14.9 0.1 0.18 12.4 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family BAAT_C PF08840.11 EWM21842.1 - 0.036 14.0 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_8 PF06259.12 EWM21842.1 - 0.17 11.5 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase COPIIcoated_ERV PF07970.12 EWM21843.1 - 6.9e-28 98.0 0.3 2.4e-27 96.2 0.0 1.9 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EWM21843.1 - 3.5e-22 78.5 0.1 6.4e-22 77.7 0.1 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Thioredoxin PF00085.20 EWM21843.1 - 1.1e-20 73.5 0.1 1.9e-20 72.7 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EWM21843.1 - 0.18 12.2 0.2 0.42 11.1 0.2 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain Tctex-1 PF03645.13 EWM21844.1 - 3.4e-19 69.0 0.7 3.4e-19 69.0 0.7 1.7 2 0 0 2 2 2 1 Tctex-1 family B2 PF11473.8 EWM21844.1 - 0.066 13.0 0.1 0.12 12.2 0.0 1.5 2 0 0 2 2 2 0 RNA binding protein B2 Rhomboid PF01694.22 EWM21845.1 - 0.59 10.1 2.0 3.2 7.8 0.5 2.4 2 0 0 2 2 2 0 Rhomboid family Snf7 PF03357.21 EWM21846.1 - 2.8e-28 98.7 12.7 5.1e-28 97.8 12.7 1.5 1 1 0 1 1 1 1 Snf7 FUSC PF04632.12 EWM21846.1 - 2.3 6.7 6.0 2.7 6.4 6.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family FOXP-CC PF16159.5 EWM21846.1 - 5.6 7.7 6.3 30 5.3 0.6 2.6 2 0 0 2 2 2 0 FOXP coiled-coil domain Metallophos PF00149.28 EWM21847.1 - 3.2e-29 102.9 0.0 6e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase His_Phos_1 PF00300.22 EWM21847.1 - 2e-17 63.6 1.3 3.6e-16 59.4 1.3 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) EF-hand_6 PF13405.6 EWM21847.1 - 0.037 13.9 0.4 0.17 11.9 0.4 2.1 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 EWM21847.1 - 0.054 13.1 1.8 0.11 12.0 0.9 2.1 2 0 0 2 2 2 0 EF hand Cytochrom_C1 PF02167.15 EWM21849.1 - 1.3e-91 306.2 0.0 1.6e-91 305.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 EWM21849.1 - 0.0005 20.3 0.0 0.0011 19.2 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III DUF2613 PF11021.8 EWM21849.1 - 0.053 13.6 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) Bromodomain PF00439.25 EWM21850.1 - 2e-08 34.2 0.0 0.0025 17.9 0.0 2.2 2 0 0 2 2 2 2 Bromodomain Acetyltransf_1 PF00583.25 EWM21851.1 - 4.6e-13 49.4 0.1 7.8e-13 48.7 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EWM21851.1 - 8.2e-10 39.0 0.1 1.9e-09 37.8 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EWM21851.1 - 8.1e-09 35.5 0.0 1e-07 31.9 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EWM21851.1 - 2e-05 24.5 0.0 4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein FGGY_N PF00370.21 EWM21852.1 - 7.5e-23 81.4 0.0 2.2e-18 66.7 0.0 2.7 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EWM21852.1 - 1.2e-18 67.6 0.4 4.6e-18 65.7 0.4 2.0 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain MreB_Mbl PF06723.13 EWM21852.1 - 0.1 11.4 0.4 0.26 10.1 0.0 1.8 2 0 0 2 2 2 0 MreB/Mbl protein UPF0172 PF03665.13 EWM21853.1 - 4.3e-32 111.7 0.0 7.1e-32 111.0 0.0 1.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.21 EWM21853.1 - 0.12 12.3 0.0 0.28 11.2 0.0 1.7 1 1 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MutS_V PF00488.21 EWM21854.1 - 2.1e-40 138.8 0.0 1.2e-39 136.4 0.0 2.1 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EWM21854.1 - 2.5e-27 96.3 1.2 4.6e-27 95.5 1.2 1.5 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 EWM21854.1 - 5.1e-05 23.5 0.0 9.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV IncE PF17627.2 EWM21854.1 - 2.8 8.0 4.6 31 4.6 0.5 3.0 3 0 0 3 3 3 0 Inclusion membrane protein E PhyH PF05721.13 EWM21858.1 - 0.022 15.0 0.0 0.096 12.9 0.0 2.0 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.6 EWM21858.1 - 0.026 15.4 0.1 0.054 14.4 0.1 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Cupin_2 PF07883.11 EWM21858.1 - 0.16 11.7 0.2 0.71 9.6 0.0 2.1 2 0 0 2 2 2 0 Cupin domain TPR_14 PF13428.6 EWM21859.1 - 1.8e-10 40.7 2.4 0.0014 19.3 0.0 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EWM21859.1 - 1.2e-09 37.6 0.7 0.0034 17.4 0.3 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 EWM21859.1 - 2.2e-09 37.7 0.2 6.5e-05 23.4 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EWM21859.1 - 5e-08 33.5 4.4 0.00014 22.4 1.3 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EWM21859.1 - 5.3e-08 32.5 0.1 0.0061 16.7 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EWM21859.1 - 5e-06 26.6 0.0 8.5e-05 22.7 0.1 1.9 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EWM21859.1 - 3.6e-05 23.8 0.8 0.14 12.3 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EWM21859.1 - 3.8e-05 23.3 0.0 0.066 13.1 0.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EWM21859.1 - 0.0011 18.8 0.1 2.6 8.3 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EWM21859.1 - 0.0044 17.3 2.9 0.025 14.9 2.2 2.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EWM21859.1 - 0.011 15.6 1.5 0.77 9.7 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EWM21859.1 - 0.023 15.3 0.2 53 4.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EWM21859.1 - 0.031 14.7 0.8 1.1 9.7 0.1 2.2 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation TPR_20 PF14561.6 EWM21859.1 - 0.16 12.3 1.8 0.71 10.2 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_assoc_2 PF16193.5 EWM21859.1 - 0.19 12.1 1.3 0.52 10.7 0.2 2.2 2 0 0 2 2 2 0 AAA C-terminal domain 5_nucleotid PF05761.14 EWM21860.1 - 2.5e-150 501.4 0.0 2.8e-150 501.2 0.0 1.0 1 0 0 1 1 1 1 5' nucleotidase family Tropomyosin_1 PF12718.7 EWM21860.1 - 0.014 15.6 0.7 0.021 15.0 0.7 1.2 1 0 0 1 1 1 0 Tropomyosin like Hydrolase_like PF13242.6 EWM21860.1 - 0.017 15.1 0.0 0.05 13.7 0.0 1.7 1 0 0 1 1 1 0 HAD-hyrolase-like HAD PF12710.7 EWM21860.1 - 0.029 14.8 0.1 1.5 9.2 0.0 2.8 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 EWM21861.1 - 2.6e-47 161.4 0.0 4.1e-47 160.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM21861.1 - 6.9e-23 81.2 0.0 1.1e-22 80.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_I PF08311.12 EWM21861.1 - 1.1e-11 44.8 0.0 2.1e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 APH PF01636.23 EWM21861.1 - 3.9e-06 27.0 4.8 0.0016 18.4 0.1 3.3 2 1 1 3 3 3 2 Phosphotransferase enzyme family Mad3_BUB1_I_2 PF17014.5 EWM21861.1 - 0.011 15.8 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein FTA2 PF13095.6 EWM21861.1 - 0.012 15.2 0.0 3.3 7.3 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EWM21861.1 - 0.024 14.3 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 EWM21861.1 - 0.096 12.0 0.0 0.3 10.4 0.0 1.7 2 0 0 2 2 2 0 Kinase-like TPR_14 PF13428.6 EWM21861.1 - 1.2 10.1 4.3 2.9 8.9 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat AIRS_C PF02769.22 EWM21862.1 - 6.9e-06 26.3 1.4 0.00025 21.2 1.4 2.7 1 1 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 EWM21862.1 - 0.00084 20.0 0.6 0.0035 17.9 0.3 2.1 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain GTP1_OBG PF01018.22 EWM21863.1 - 5.6e-32 110.5 12.0 5.6e-32 110.5 12.0 2.7 3 0 0 3 3 3 1 GTP1/OBG MMR_HSR1 PF01926.23 EWM21863.1 - 9.3e-22 77.3 0.0 4.4e-21 75.1 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EWM21863.1 - 1e-07 31.6 0.0 6.7e-07 29.0 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 EWM21863.1 - 0.0055 15.7 1.1 1 8.3 0.0 2.8 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 EWM21863.1 - 0.047 13.1 0.0 0.24 10.8 0.0 2.1 1 1 0 1 1 1 0 ADP-ribosylation factor family Glyco_transf_36 PF06165.11 EWM21865.1 - 0.043 13.2 0.0 0.047 13.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 36 KAR9 PF08580.10 EWM21867.1 - 0.063 11.8 0.8 0.084 11.4 0.8 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Pyr_redox_2 PF07992.14 EWM21868.1 - 2.5e-11 43.4 0.1 1.1e-08 34.7 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EWM21868.1 - 0.00027 21.1 0.0 0.001 19.3 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EWM21868.1 - 0.00029 20.1 0.5 0.62 9.3 0.1 2.3 2 0 0 2 2 2 2 Thi4 family NAD_binding_9 PF13454.6 EWM21868.1 - 0.0038 17.2 0.0 0.012 15.6 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 EWM21868.1 - 0.011 16.3 0.0 4.9 7.8 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EWM21868.1 - 0.15 11.4 0.6 0.5 9.6 0.2 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Kelch_1 PF01344.25 EWM21870.1 - 2.1e-25 88.0 11.7 1.8e-07 30.6 0.1 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 EWM21870.1 - 4.5e-19 68.0 4.4 0.0052 17.0 0.0 6.7 6 1 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 EWM21870.1 - 2e-11 43.4 3.9 0.0004 20.2 0.0 5.6 6 0 0 6 6 6 3 Kelch motif Kelch_4 PF13418.6 EWM21870.1 - 0.0025 17.8 14.9 0.073 13.1 0.1 6.0 7 1 1 8 8 8 2 Galactose oxidase, central domain Kelch_3 PF13415.6 EWM21870.1 - 0.096 13.0 11.8 11 6.5 0.4 5.1 4 2 1 5 5 5 0 Galactose oxidase, central domain ubiquitin PF00240.23 EWM21871.1 - 2e-08 33.9 0.0 3e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EWM21871.1 - 0.063 13.1 0.0 0.085 12.7 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like TPR_12 PF13424.6 EWM21872.1 - 7.2e-26 90.3 34.8 3e-10 40.2 0.3 7.0 5 2 3 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 EWM21872.1 - 4.1e-09 35.9 21.0 0.042 13.7 0.2 7.0 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 EWM21872.1 - 9.8e-08 31.5 18.8 0.35 11.0 0.1 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EWM21872.1 - 1.2e-05 24.9 3.2 1.2e-05 24.9 3.2 3.8 3 2 1 4 4 4 1 MalT-like TPR region TPR_8 PF13181.6 EWM21872.1 - 2.2e-05 24.3 15.5 0.11 12.8 0.0 6.7 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 EWM21872.1 - 2.6e-05 24.0 33.3 0.094 12.9 0.7 8.3 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_10 PF13374.6 EWM21872.1 - 0.0011 18.8 43.4 0.0043 16.9 0.4 9.0 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.6 EWM21872.1 - 0.0039 17.7 19.6 0.47 11.2 0.1 7.0 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_5 PF12688.7 EWM21872.1 - 0.011 15.9 1.2 0.011 15.9 1.2 3.5 4 0 0 4 4 4 0 Tetratrico peptide repeat TPR_19 PF14559.6 EWM21872.1 - 0.012 16.1 25.1 0.026 15.0 0.1 6.3 5 1 2 7 7 6 0 Tetratricopeptide repeat Vps39_1 PF10366.9 EWM21872.1 - 0.088 13.1 0.1 1.2 9.5 0.0 2.8 2 2 1 3 3 3 0 Vacuolar sorting protein 39 domain 1 TPR_17 PF13431.6 EWM21872.1 - 0.09 13.2 3.8 1e+02 3.7 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat tRNA_synthFbeta PF17759.1 EWM21872.1 - 0.13 11.7 0.1 0.52 9.7 0.0 2.0 2 0 0 2 2 2 0 Phenylalanyl tRNA synthetase beta chain CLM domain DUF3856 PF12968.7 EWM21872.1 - 0.27 11.3 4.4 0.54 10.3 0.1 3.2 3 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) DUF627 PF04781.12 EWM21872.1 - 0.31 11.1 3.8 6.9 6.7 0.0 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF627) TPR_14 PF13428.6 EWM21872.1 - 0.75 10.8 44.3 12 7.0 0.5 9.2 7 2 2 9 9 9 0 Tetratricopeptide repeat Methyltransf_18 PF12847.7 EWM21873.1 - 2.4e-23 82.7 0.0 6.9e-23 81.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain TrmK PF04816.12 EWM21873.1 - 7.6e-15 55.0 0.0 2.3e-14 53.4 0.0 1.7 1 1 0 1 1 1 1 tRNA (adenine(22)-N(1))-methyltransferase Methyltransf_31 PF13847.6 EWM21873.1 - 0.00058 19.7 0.0 0.0017 18.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM21873.1 - 0.011 16.4 0.1 0.096 13.4 0.0 2.4 1 1 2 3 3 3 0 Methyltransferase domain MTS PF05175.14 EWM21873.1 - 0.018 14.6 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Adaptin_N PF01602.20 EWM21875.1 - 3.3e-110 369.1 0.5 4.1e-110 368.8 0.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EWM21875.1 - 5.2e-24 85.1 1.5 1.5e-21 77.1 0.3 3.3 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 AP3B1_C PF14796.6 EWM21875.1 - 1.2e-08 35.3 0.0 2.5e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Clathrin-adaptor complex-3 beta-1 subunit C-terminal HEAT_2 PF13646.6 EWM21875.1 - 1.4e-06 28.6 13.0 0.00015 22.1 1.7 5.0 3 1 0 4 4 4 2 HEAT repeats SPO22 PF08631.10 EWM21875.1 - 0.002 17.7 0.0 0.0047 16.5 0.0 1.6 1 0 0 1 1 1 1 Meiosis protein SPO22/ZIP4 like HEAT PF02985.22 EWM21875.1 - 0.0074 16.5 6.7 1.2 9.6 0.0 5.0 5 1 1 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 EWM21875.1 - 0.57 10.7 13.7 0.19 12.3 0.9 5.5 5 1 1 6 6 6 0 HEAT-like repeat Adaptin_N PF01602.20 EWM21876.1 - 2e-103 346.8 0.5 2.4e-103 346.5 0.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EWM21876.1 - 4.9e-24 85.2 1.5 1.4e-21 77.2 0.3 3.2 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 AP3B1_C PF14796.6 EWM21876.1 - 1.2e-08 35.4 0.0 2.4e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Clathrin-adaptor complex-3 beta-1 subunit C-terminal HEAT_2 PF13646.6 EWM21876.1 - 1.2e-06 28.8 13.1 0.00014 22.1 1.7 5.1 3 1 0 4 4 4 2 HEAT repeats SPO22 PF08631.10 EWM21876.1 - 0.0019 17.8 0.0 0.0044 16.5 0.0 1.6 1 0 0 1 1 1 1 Meiosis protein SPO22/ZIP4 like HEAT PF02985.22 EWM21876.1 - 0.0065 16.6 6.8 1.1 9.6 0.0 5.0 5 1 1 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 EWM21876.1 - 0.45 11.1 13.6 0.18 12.4 0.8 5.5 5 1 1 6 6 6 0 HEAT-like repeat TPR_10 PF13374.6 EWM21877.1 - 0.3 11.0 1.1 0.69 9.9 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Rho_N PF07498.12 EWM21877.1 - 0.39 10.7 4.4 4.5 7.3 0.4 2.9 3 0 0 3 3 3 0 Rho termination factor, N-terminal domain Ribosomal_S6e PF01092.19 EWM21878.1 - 5.1e-56 188.0 0.5 9.5e-56 187.2 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e AAA_12 PF13087.6 EWM21879.1 - 1.6e-55 187.9 0.0 6e-55 186.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EWM21879.1 - 9.2e-44 150.2 3.7 1.2e-24 87.6 0.1 3.2 2 1 1 3 3 3 2 AAA domain AAA_19 PF13245.6 EWM21879.1 - 2.2e-14 54.0 0.0 3.1e-13 50.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EWM21879.1 - 7.6e-12 45.3 4.6 2.4e-11 43.7 0.2 3.0 2 1 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 EWM21879.1 - 0.00015 21.4 0.1 0.00078 19.1 0.1 1.9 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain PhoH PF02562.16 EWM21879.1 - 0.0036 16.8 0.0 0.082 12.3 0.0 2.8 3 0 0 3 3 3 1 PhoH-like protein Viral_helicase1 PF01443.18 EWM21879.1 - 0.01 15.6 0.0 0.48 10.1 0.0 2.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 EWM21879.1 - 0.025 14.6 0.0 0.063 13.3 0.0 1.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PIF1 PF05970.14 EWM21879.1 - 0.033 13.3 0.0 1.6 7.8 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase AAA_25 PF13481.6 EWM21879.1 - 0.048 13.2 0.1 0.12 11.9 0.1 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EWM21879.1 - 0.083 12.3 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 EWM21879.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.9 EWM21879.1 - 0.1 11.8 0.4 0.6 9.3 0.0 2.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) ANAPC4_WD40 PF12894.7 EWM21880.1 - 5.2e-07 29.9 0.0 3.4 8.0 0.0 5.0 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EWM21880.1 - 1.4e-06 28.9 0.0 7.1 7.7 0.0 5.4 6 0 0 6 6 6 2 WD domain, G-beta repeat PD40 PF07676.12 EWM21880.1 - 0.0071 16.3 0.0 0.24 11.4 0.0 2.7 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 EWM21880.1 - 0.088 11.3 0.0 0.19 10.2 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain GTP_EFTU PF00009.27 EWM21881.1 - 2e-47 161.2 0.0 3.1e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RF3_C PF16658.5 EWM21881.1 - 4e-39 133.4 0.0 8.2e-39 132.4 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_II PF14492.6 EWM21881.1 - 3.5e-05 23.8 0.0 8.6e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EWM21881.1 - 4.7e-05 23.4 0.0 9.1e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 EWM21881.1 - 0.00039 20.7 0.0 0.00076 19.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SRPRB PF09439.10 EWM21881.1 - 0.056 12.9 0.0 0.2 11.0 0.0 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit adh_short PF00106.25 EWM21882.1 - 1.2e-45 155.4 0.8 1.5e-45 155.1 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EWM21882.1 - 5.9e-30 104.6 0.4 8.4e-30 104.1 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM21882.1 - 1.8e-13 50.8 0.2 2.6e-13 50.3 0.2 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EWM21882.1 - 0.00089 18.5 0.1 0.0013 17.9 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein UPF0139 PF03669.13 EWM21883.1 - 3.4e-13 49.3 0.0 4.3e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) potato_inhibit PF00280.18 EWM21884.1 - 3.9e-22 78.7 0.2 6e-22 78.1 0.2 1.3 1 0 0 1 1 1 1 Potato inhibitor I family DUF2000 PF09391.10 EWM21884.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2000) potato_inhibit PF00280.18 EWM21885.1 - 2.9e-22 79.1 0.1 4.5e-22 78.5 0.1 1.3 1 0 0 1 1 1 1 Potato inhibitor I family Inhibitor_I78 PF11720.8 EWM21885.1 - 0.038 14.0 0.0 0.065 13.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase inhibitor I78 family Spc7 PF08317.11 EWM21886.1 - 0.0015 17.5 11.5 0.0015 17.5 11.5 3.0 2 1 1 3 3 3 1 Spc7 kinetochore protein DUF4349 PF14257.6 EWM21886.1 - 0.0042 16.6 7.8 0.0042 16.6 7.8 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4349) Bacillus_HBL PF05791.11 EWM21886.1 - 0.012 15.4 0.2 0.012 15.4 0.2 2.8 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) SHIPPO-rpt PF07004.12 EWM21887.1 - 1.2e-08 35.5 19.2 0.011 16.6 0.1 5.4 5 0 0 5 5 5 5 Sperm-tail PG-rich repeat HrcA_DNA-bdg PF03444.15 EWM21888.1 - 0.038 13.6 0.1 0.08 12.6 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding PUB_1 PF18486.1 EWM21888.1 - 0.05 13.5 0.0 0.24 11.3 0.0 2.2 1 0 0 1 1 1 0 PNGase/UBA- or UBX-containing domain Toxin_22 PF08092.11 EWM21888.1 - 0.099 12.7 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 Magi peptide toxin family TPR_10 PF13374.6 EWM21888.1 - 0.49 10.3 5.6 3 7.8 1.7 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DEAD PF00270.29 EWM21889.1 - 3.3e-28 98.6 0.0 1.6e-17 63.8 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EWM21889.1 - 6.3e-16 58.7 0.0 1.5e-15 57.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EWM21889.1 - 0.00037 20.5 0.0 0.00057 19.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DNA_pol_A_exo1 PF01612.20 EWM21890.1 - 1e-10 41.6 0.0 1.5e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease Sel1 PF08238.12 EWM21891.1 - 4.4e-13 49.4 0.0 0.0016 19.0 0.0 4.9 5 0 0 5 5 5 4 Sel1 repeat Destabilase PF05497.12 EWM21891.1 - 0.063 13.6 0.8 1.2 9.5 0.0 2.5 2 0 0 2 2 2 0 Destabilase DUF1955 PF09205.10 EWM21891.1 - 0.14 11.9 0.0 0.14 11.9 0.0 2.6 3 1 1 4 4 4 0 Domain of unknown function (DUF1955) Beta-lactamase PF00144.24 EWM21892.1 - 8.3e-37 127.2 0.1 2.2e-32 112.6 0.0 2.3 2 0 0 2 2 2 2 Beta-lactamase ABC1 PF03109.16 EWM21892.1 - 3.9e-28 98.0 0.0 7e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 ABC1 family FYVE PF01363.21 EWM21892.1 - 2.9e-09 37.0 13.8 6.1e-09 35.9 13.8 1.5 1 0 0 1 1 1 1 FYVE zinc finger SCP2 PF02036.17 EWM21892.1 - 0.00023 21.6 0.0 0.00052 20.5 0.0 1.6 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 EWM21892.1 - 0.0094 16.2 0.0 0.041 14.1 0.0 1.9 2 0 0 2 2 2 1 Alkyl sulfatase C-terminal zf-ribbon_3 PF13248.6 EWM21892.1 - 0.015 14.7 0.7 0.042 13.3 0.7 1.7 1 0 0 1 1 1 0 zinc-ribbon domain FYVE_2 PF02318.16 EWM21892.1 - 2 8.6 7.0 5 7.4 7.0 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger NUDIX PF00293.28 EWM21893.1 - 2.7e-18 66.3 0.0 4e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain AAA PF00004.29 EWM21895.1 - 1.6e-32 112.7 0.0 3.6e-32 111.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EWM21895.1 - 2.6e-11 43.1 0.0 6.6e-11 41.8 0.0 1.7 1 1 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EWM21895.1 - 4.9e-05 23.8 0.0 0.0023 18.4 0.0 2.6 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EWM21895.1 - 5.4e-05 23.0 0.0 9.8e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EWM21895.1 - 0.00058 20.0 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EWM21895.1 - 0.0012 18.9 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EWM21895.1 - 0.0012 19.0 0.0 0.0029 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EWM21895.1 - 0.0016 18.7 0.3 0.083 13.2 0.0 2.8 2 2 1 3 3 3 1 AAA domain DUF815 PF05673.13 EWM21895.1 - 0.0027 16.9 0.0 0.0047 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 EWM21895.1 - 0.004 17.2 0.1 0.1 12.6 0.1 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EWM21895.1 - 0.0054 16.0 0.3 0.013 14.8 0.2 1.6 1 1 1 2 2 2 1 TIP49 P-loop domain Mg_chelatase PF01078.21 EWM21895.1 - 0.0072 15.7 0.2 0.016 14.6 0.2 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EWM21895.1 - 0.008 15.9 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EWM21895.1 - 0.0091 15.7 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Parvo_NS1 PF01057.17 EWM21895.1 - 0.011 14.9 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_18 PF13238.6 EWM21895.1 - 0.012 16.1 0.0 0.025 15.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EWM21895.1 - 0.013 15.7 0.6 0.026 14.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 EWM21895.1 - 0.025 14.4 0.0 0.062 13.1 0.0 1.6 2 0 0 2 2 2 0 Bacterial dnaA protein RNA_helicase PF00910.22 EWM21895.1 - 0.028 14.8 0.0 0.083 13.3 0.0 1.8 2 0 0 2 2 1 0 RNA helicase TsaE PF02367.17 EWM21895.1 - 0.028 14.4 0.1 0.064 13.3 0.0 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 EWM21895.1 - 0.042 13.5 0.0 0.087 12.5 0.0 1.5 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 EWM21895.1 - 0.06 13.3 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 EWM21895.1 - 0.078 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 EWM21895.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin TniB PF05621.11 EWM21895.1 - 0.13 11.7 0.0 13 5.2 0.0 2.4 1 1 1 2 2 2 0 Bacterial TniB protein AAA_21 PF13304.6 EWM21895.1 - 0.27 11.0 0.9 4.1 7.1 0.2 2.3 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 EWM21896.1 - 6.4e-38 130.2 0.0 1.2e-37 129.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EWM21896.1 - 5e-08 32.8 0.0 1.1e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.14 EWM21896.1 - 1.6e-06 28.2 0.1 2.2e-05 24.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EWM21896.1 - 1.4e-05 24.9 0.0 2.9e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 EWM21896.1 - 4.3e-05 23.2 0.0 0.00012 21.8 0.0 1.8 1 1 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 EWM21896.1 - 0.00054 20.2 0.7 0.017 15.4 0.0 2.8 2 1 1 3 3 3 1 AAA domain TIP49 PF06068.13 EWM21896.1 - 0.00055 19.3 0.0 0.00099 18.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 EWM21896.1 - 0.00064 20.1 3.3 0.0048 17.3 0.7 3.2 2 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 EWM21896.1 - 0.0045 16.7 0.0 0.0097 15.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EWM21896.1 - 0.015 14.7 0.1 0.039 13.3 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EWM21896.1 - 0.029 14.4 0.0 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 EWM21896.1 - 0.04 14.0 0.0 0.091 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Parvo_NS1 PF01057.17 EWM21896.1 - 0.048 12.7 0.0 0.081 12.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 EWM21896.1 - 0.055 13.2 0.0 0.62 9.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 EWM21896.1 - 0.057 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.6 EWM21896.1 - 0.069 13.4 0.0 0.21 11.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EWM21896.1 - 0.069 12.7 0.4 1.5 8.3 0.1 2.5 1 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EWM21896.1 - 0.09 13.3 0.0 0.26 11.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 EWM21896.1 - 0.12 12.8 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 EWM21896.1 - 0.12 12.5 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain CHD5 PF04420.14 EWM21897.1 - 0.00016 21.6 0.1 0.00019 21.3 0.1 1.2 1 0 0 1 1 1 1 CHD5-like protein JmjC PF02373.22 EWM21898.1 - 1.8e-41 141.2 0.1 4.3e-41 139.9 0.1 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 EWM21898.1 - 1.5e-13 50.5 1.4 5.1e-13 48.7 0.0 2.5 2 0 0 2 2 2 1 jmjN domain zinc-ribbons_6 PF07191.12 EWM21898.1 - 0.0084 16.1 0.6 0.026 14.5 0.6 1.8 1 0 0 1 1 1 1 zinc-ribbons PHD PF00628.29 EWM21898.1 - 0.037 13.9 4.2 0.085 12.8 4.2 1.7 1 0 0 1 1 1 0 PHD-finger Cullin PF00888.22 EWM21899.1 - 3.2e-12 45.9 0.0 3.8e-12 45.6 0.0 1.0 1 0 0 1 1 1 1 Cullin family AIM24 PF01987.17 EWM21900.1 - 9.1e-58 195.4 3.0 1.2e-57 195.0 3.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DnaJ PF00226.31 EWM21901.1 - 5.1e-15 55.3 0.0 1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 EWM21901.1 - 0.065 13.2 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 A repeated domain in UCH-protein Methyltransf_11 PF08241.12 EWM21902.1 - 6.3e-06 26.8 0.0 1.4e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EWM21902.1 - 0.00072 19.4 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM21902.1 - 0.046 14.4 0.0 0.089 13.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EWM21902.1 - 0.16 11.8 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 EWM21902.1 - 0.21 10.5 0.0 0.32 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) tRNA-synt_1c PF00749.21 EWM21903.1 - 2.4e-98 328.9 0.2 3.6e-98 328.3 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EWM21903.1 - 2.2e-34 118.9 0.0 5.7e-34 117.5 0.0 1.8 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain UPF0016 PF01169.19 EWM21904.1 - 7.2e-34 116.0 32.7 2.6e-18 66.1 7.3 3.3 3 0 0 3 3 3 2 Uncharacterized protein family UPF0016 Rx_N PF18052.1 EWM21905.1 - 0.32 11.3 3.3 22 5.4 0.0 3.1 3 1 0 3 3 3 0 Rx N-terminal domain YGGT PF02325.17 EWM21906.1 - 1e-12 48.3 7.5 1.5e-12 47.8 6.9 1.7 1 1 0 1 1 1 1 YGGT family NUDIX PF00293.28 EWM21907.1 - 1.3e-11 44.7 0.0 2.2e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.11 EWM21907.1 - 5.2e-05 22.8 6.3 9.7e-05 21.9 6.3 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain NUDIX-like PF09296.11 EWM21907.1 - 7.7e-05 23.3 0.0 0.00015 22.3 0.0 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain Zn_ribbon_recom PF13408.6 EWM21907.1 - 0.1 13.1 0.3 0.29 11.7 0.3 1.8 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Ribosomal_S15 PF00312.22 EWM21908.1 - 9.4e-21 73.8 0.5 1.5e-20 73.1 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 Ribosomal_S15 PF00312.22 EWM21909.1 - 9.4e-21 73.8 0.5 1.5e-20 73.1 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 zf-RING_2 PF13639.6 EWM21910.1 - 8.6e-11 42.0 15.4 3.3e-10 40.1 9.8 2.5 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EWM21910.1 - 1.1e-07 31.6 12.6 6.3e-07 29.1 9.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EWM21910.1 - 2.4e-06 27.2 6.5 2.4e-06 27.2 6.5 2.8 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4 PF00097.25 EWM21910.1 - 8e-05 22.4 9.3 0.0029 17.4 8.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EWM21910.1 - 0.00051 19.9 11.1 0.001 19.0 7.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EWM21910.1 - 0.00072 19.4 7.6 0.00072 19.4 7.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EWM21910.1 - 0.0018 18.5 17.4 0.021 15.1 11.2 3.2 2 2 1 3 3 3 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EWM21910.1 - 0.055 13.5 12.6 0.96 9.5 9.5 2.5 2 0 0 2 2 2 0 RING-type zinc-finger Actin PF00022.19 EWM21911.1 - 1.8e-95 319.9 0.0 2.2e-95 319.7 0.0 1.1 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EWM21911.1 - 4.3e-05 22.5 0.0 0.12 11.2 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein CDC45 PF02724.14 EWM21913.1 - 2e-164 548.4 9.7 3.5e-123 412.2 3.1 2.0 1 1 1 2 2 2 2 CDC45-like protein TetR_C_22 PF17928.1 EWM21913.1 - 0.09 13.1 0.3 0.2 12.0 0.3 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain LON_substr_bdg PF02190.16 EWM21914.1 - 3.9e-11 43.2 0.0 6.2e-10 39.3 0.0 2.1 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Yippee-Mis18 PF03226.14 EWM21914.1 - 1.8e-05 24.9 0.1 3.2e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Phage_glycop_gL PF11108.8 EWM21914.1 - 0.016 15.2 0.0 0.075 13.1 0.0 2.1 2 0 0 2 2 2 0 Viral glycoprotein L Tat PF00539.18 EWM21914.1 - 0.21 11.8 3.8 7.8 6.7 0.2 2.6 2 0 0 2 2 2 0 Transactivating regulatory protein (Tat) GSH_synth_ATP PF03917.17 EWM21915.1 - 7.7e-123 410.0 0.0 9e-123 409.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 EWM21915.1 - 4.3e-28 97.8 0.0 7.9e-28 96.9 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Fasciclin PF02469.22 EWM21916.1 - 2.8e-67 224.8 0.0 4.2e-16 59.3 0.0 6.4 6 0 0 6 6 6 6 Fasciclin domain Methyltransf_16 PF10294.9 EWM21917.1 - 1.2e-29 103.3 0.0 1.8e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EWM21917.1 - 0.0063 16.4 0.0 0.0088 15.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain LRR_4 PF12799.7 EWM21918.1 - 1.8e-15 56.8 35.5 0.11 13.0 0.0 11.1 6 2 9 16 16 16 10 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EWM21918.1 - 1.1e-14 53.1 41.1 0.38 10.9 0.3 16.2 18 1 1 19 19 19 7 Leucine Rich repeat LRR_8 PF13855.6 EWM21918.1 - 5.7e-13 48.4 27.2 1.3e-05 24.9 0.4 7.6 5 2 2 7 7 7 5 Leucine rich repeat LRR_9 PF14580.6 EWM21918.1 - 0.0061 16.1 8.1 3.7 7.0 0.1 5.6 3 2 4 7 7 7 2 Leucine-rich repeat DUF3638 PF12340.8 EWM21919.1 - 4.6e-21 75.2 0.0 1.2e-18 67.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3638) DUF3645 PF12359.8 EWM21919.1 - 3.9e-17 61.3 0.1 9.1e-17 60.2 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) EF-hand_1 PF00036.32 EWM21919.1 - 2.3e-10 39.3 1.3 8.2e-05 21.9 0.2 4.2 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 EWM21919.1 - 6e-10 39.4 5.2 2.4e-05 24.7 0.1 3.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EWM21919.1 - 1.1e-09 37.4 4.3 0.0066 16.3 0.1 4.1 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 EWM21919.1 - 3.9e-05 23.4 5.1 4.1e-05 23.3 0.2 3.4 3 1 0 3 3 3 1 EF-hand domain pair Vps62 PF06101.11 EWM21919.1 - 0.00012 20.6 0.0 0.00022 19.7 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 EF-hand_5 PF13202.6 EWM21919.1 - 0.00039 19.8 0.2 0.0017 17.8 0.2 2.1 1 0 0 1 1 1 1 EF hand RR_TM4-6 PF06459.12 EWM21919.1 - 0.029 14.2 5.6 0.088 12.6 5.6 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 ResIII PF04851.15 EWM21919.1 - 0.035 14.1 0.0 0.088 12.8 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_23 PF13476.6 EWM21919.1 - 0.79 10.2 6.3 2.1 8.8 6.3 1.6 1 0 0 1 1 1 0 AAA domain DUF3824 PF12868.7 EWM21919.1 - 3.1 8.5 6.6 5.9 7.6 6.6 1.4 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Peptidase_M1 PF01433.20 EWM21920.1 - 4.9e-85 284.5 2.5 9.1e-85 283.6 2.4 1.5 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 EWM21920.1 - 7.4e-71 239.3 0.0 1.3e-70 238.5 0.0 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 EWM21920.1 - 8.9e-47 159.7 0.0 1.3e-46 159.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain SprT-like PF10263.9 EWM21920.1 - 0.049 13.5 0.0 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 SprT-like family Peptidase_M78 PF06114.13 EWM21920.1 - 0.15 12.0 0.0 0.82 9.6 0.0 2.1 2 0 0 2 2 2 0 IrrE N-terminal-like domain UAA PF08449.11 EWM21922.1 - 7.8e-44 150.1 14.0 2.7e-43 148.3 14.0 1.7 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 EWM21922.1 - 6e-06 26.5 9.1 6e-06 26.5 9.1 2.8 2 1 0 2 2 2 1 EamA-like transporter family TPT PF03151.16 EWM21922.1 - 0.0012 18.3 3.8 0.0012 18.3 3.8 2.1 2 0 0 2 2 2 1 Triose-phosphate Transporter family Phage_holin_2_4 PF16082.5 EWM21922.1 - 0.16 11.8 1.2 0.65 9.8 0.0 2.5 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like TMEM234 PF10639.9 EWM21922.1 - 4.4 7.4 7.7 8.6 6.4 1.6 2.5 2 0 0 2 2 2 0 Putative transmembrane family 234 UPRTase PF14681.6 EWM21924.1 - 1.7e-61 207.3 0.0 2.1e-61 207.0 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EWM21924.1 - 0.0032 17.0 0.2 0.0082 15.7 0.2 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain FHA PF00498.26 EWM21926.1 - 6.7e-10 39.2 0.0 1.1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.6 EWM21926.1 - 3.8e-05 23.9 13.6 7.5e-05 23.0 8.9 2.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 EWM21926.1 - 6.5e-05 22.7 12.7 8.7e-05 22.3 9.7 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EWM21926.1 - 9e-05 22.4 3.1 9e-05 22.4 3.1 3.2 5 0 0 5 5 5 1 RING-type zinc-finger zf-RING_5 PF14634.6 EWM21926.1 - 9.4e-05 22.3 9.3 9.4e-05 22.3 9.3 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EWM21926.1 - 0.0034 17.5 9.0 0.0034 17.5 9.0 2.9 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EWM21926.1 - 0.0053 16.6 7.5 0.0053 16.6 7.5 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EWM21926.1 - 0.01 15.7 8.3 0.01 15.7 8.3 2.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Yop-YscD_cpl PF16697.5 EWM21926.1 - 0.039 14.3 0.1 0.11 12.8 0.0 1.8 2 0 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain Agenet PF05641.12 EWM21927.1 - 1.4e-07 31.9 10.9 0.0025 18.2 0.9 2.7 2 1 0 2 2 2 2 Agenet domain Tudor-knot PF11717.8 EWM21927.1 - 3.4e-05 23.6 2.9 3.4e-05 23.6 2.9 1.9 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain F-box-like PF12937.7 EWM21927.1 - 0.0025 17.6 0.0 0.0049 16.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EWM21927.1 - 0.0063 16.4 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 F-box domain Cullin PF00888.22 EWM21928.1 - 4.7e-84 283.1 0.0 2.6e-52 178.3 0.3 2.1 2 0 0 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.9 EWM21928.1 - 1.6e-07 31.2 0.1 2.9e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 Cullin protein neddylation domain HSA PF07529.13 EWM21929.1 - 2.2e-15 56.7 7.7 2.2e-15 56.7 7.7 2.6 2 1 1 3 3 3 1 HSA DBINO PF13892.6 EWM21929.1 - 0.00048 20.5 11.1 0.008 16.5 11.1 2.3 1 1 0 1 1 1 1 DNA-binding domain DUF3611 PF12263.8 EWM21930.1 - 3.6e-40 137.7 10.3 5.4e-40 137.1 10.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3611) NifU PF01106.17 EWM21931.1 - 1.2e-30 105.4 0.4 3.5e-25 87.9 0.2 2.2 2 0 0 2 2 2 2 NifU-like domain Sds3 PF08598.11 EWM21932.1 - 0.0061 16.6 1.6 0.011 15.7 1.6 1.4 1 0 0 1 1 1 1 Sds3-like IKBKB_SDD PF18397.1 EWM21936.1 - 0.0039 16.5 0.5 0.0041 16.5 0.5 1.0 1 0 0 1 1 1 1 IQBAL scaffold dimerization domain ECH_1 PF00378.20 EWM21937.1 - 3.8e-27 95.2 0.0 5.1e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EWM21937.1 - 7.6e-13 48.6 0.1 1.1e-12 48.1 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase MitMem_reg PF13012.6 EWM21938.1 - 6.4e-16 58.8 0.0 1e-15 58.1 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EWM21938.1 - 1.4e-13 50.8 0.0 2.2e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease JAB PF01398.21 EWM21939.1 - 1e-21 77.1 0.2 1.4e-21 76.6 0.2 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease BRCC36_C PF18110.1 EWM21939.1 - 6.4e-12 45.5 0.0 1.2e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 BRCC36 C-terminal helical domain Prok-JAB PF14464.6 EWM21939.1 - 6.3e-07 29.2 0.3 1.2e-06 28.3 0.3 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain SNF2_N PF00176.23 EWM21940.1 - 2.4e-21 75.8 0.1 3.2e-21 75.5 0.1 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EWM21940.1 - 1.8e-20 73.4 0.0 2.7e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 EWM21940.1 - 0.024 13.8 0.0 0.29 10.3 0.0 2.0 2 0 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 EWM21940.1 - 0.21 10.8 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Activator_LAG-3 PF11498.8 EWM21941.1 - 0.086 11.8 58.6 0.11 11.5 58.6 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 EPL1 PF10513.9 EWM21941.1 - 0.41 11.0 9.5 0.52 10.7 9.5 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like PAT1 PF09770.9 EWM21941.1 - 3.2 5.9 29.9 3.7 5.7 29.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hydin_ADK PF17213.3 EWM21941.1 - 3.6 7.8 7.5 5.1 7.3 7.5 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DIM1 PF02966.16 EWM21942.1 - 1.6e-65 218.9 0.7 2e-65 218.6 0.7 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 EWM21942.1 - 0.065 13.2 0.1 0.09 12.8 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin DUF179 PF02622.15 EWM21943.1 - 1.7e-18 67.1 0.0 7.8e-18 64.9 0.0 1.9 1 1 0 1 1 1 1 Uncharacterized ACR, COG1678 RINGv PF12906.7 EWM21943.1 - 3.1e-11 43.2 5.4 5.9e-11 42.3 5.4 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 EWM21943.1 - 2.8 8.3 6.3 10 6.5 6.7 1.7 1 1 1 2 2 2 0 Ring finger domain ABC2_membrane PF01061.24 EWM21944.1 - 9.6e-41 139.5 12.9 9.6e-41 139.5 12.9 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 EWM21944.1 - 6.9e-24 84.9 0.0 1.1e-23 84.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EWM21944.1 - 2.8e-07 30.6 0.0 0.011 15.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 EWM21944.1 - 0.00027 20.2 18.3 0.00045 19.4 18.3 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_29 PF13555.6 EWM21944.1 - 0.00046 19.9 0.4 0.001 18.8 0.4 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EWM21944.1 - 0.00056 19.4 0.1 0.8 9.1 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EWM21944.1 - 0.0014 19.1 0.0 0.0029 18.0 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain ABC2_membrane_2 PF12679.7 EWM21944.1 - 0.0027 17.1 10.6 0.0034 16.7 10.2 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 EWM21944.1 - 0.0031 17.4 0.2 0.0071 16.3 0.2 1.5 1 0 0 1 1 1 1 RsgA GTPase MCM PF00493.23 EWM21944.1 - 0.043 12.9 0.0 0.099 11.7 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain AAA_23 PF13476.6 EWM21944.1 - 0.1 13.1 0.2 0.17 12.4 0.2 1.3 1 0 0 1 1 1 0 AAA domain HALZ PF02183.18 EWM21945.1 - 0.00019 21.6 13.8 0.0026 17.9 1.1 4.1 3 0 0 3 3 3 2 Homeobox associated leucine zipper DUF4407 PF14362.6 EWM21945.1 - 0.034 13.5 31.6 0.03 13.7 12.8 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) YabA PF06156.13 EWM21945.1 - 0.17 12.6 26.9 4.8 7.9 5.6 4.5 2 1 2 4 4 4 0 Initiation control protein YabA UPF0184 PF03670.13 EWM21945.1 - 0.18 12.2 1.5 0.72 10.3 0.9 2.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) DUF1664 PF07889.12 EWM21945.1 - 2.6 8.1 18.3 0.1 12.6 2.1 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) RasGAP_C PF03836.15 EWM21945.1 - 4.3 7.5 15.7 5.1 7.3 4.1 3.7 2 1 1 3 3 3 0 RasGAP C-terminus Spc7 PF08317.11 EWM21945.1 - 5 5.9 44.4 0.37 9.6 10.6 3.5 2 1 1 3 3 3 0 Spc7 kinetochore protein HAUS5 PF14817.6 EWM21945.1 - 9.3 4.9 30.9 0.041 12.7 15.2 2.5 1 1 0 2 2 2 0 HAUS augmin-like complex subunit 5 Metallophos PF00149.28 EWM21946.1 - 1.1e-06 29.2 0.9 2e-06 28.5 0.9 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF745 PF05335.13 EWM21947.1 - 0.0046 16.7 23.2 0.022 14.5 16.3 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF745) Pox_A_type_inc PF04508.12 EWM21947.1 - 0.019 14.8 3.9 0.28 11.1 0.3 3.3 1 1 1 2 2 2 0 Viral A-type inclusion protein repeat RTP PF02334.16 EWM21947.1 - 0.18 12.4 1.7 0.49 11.0 1.5 1.7 1 1 0 1 1 1 0 Replication terminator protein LPP PF04728.13 EWM21947.1 - 2.4 8.6 9.3 4.3 7.8 0.8 3.7 3 1 1 4 4 4 0 Lipoprotein leucine-zipper FliJ PF02050.16 EWM21947.1 - 2.8 8.2 22.4 4 7.7 11.7 2.7 1 1 1 2 2 2 0 Flagellar FliJ protein DUF724 PF05266.14 EWM21947.1 - 3.8 7.3 24.3 1.7 8.4 2.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF4446 PF14584.6 EWM21947.1 - 4.2 7.4 10.9 4.6 7.2 0.0 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) Rootletin PF15035.6 EWM21947.1 - 5.5 7.0 22.0 0.69 9.9 0.3 2.8 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Atg14 PF10186.9 EWM21947.1 - 7.4 5.6 20.9 1.2 8.2 7.2 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Chloroa_b-bind PF00504.21 EWM21948.1 - 2.1e-37 129.1 0.0 3.1e-37 128.6 0.0 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DUF2059 PF09832.9 EWM21949.1 - 1.7e-07 31.2 0.0 3.1e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2059) Spc7 PF08317.11 EWM21950.1 - 0.016 14.1 12.7 0.043 12.7 11.8 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein TMCO5 PF14992.6 EWM21950.1 - 0.063 12.8 5.9 0.11 12.0 5.9 1.3 1 0 0 1 1 1 0 TMCO5 family DUF1664 PF07889.12 EWM21950.1 - 0.47 10.5 4.4 1.2 9.2 4.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Macoilin PF09726.9 EWM21950.1 - 0.48 8.9 7.8 0.59 8.6 7.8 1.2 1 0 0 1 1 1 0 Macoilin family UPF0242 PF06785.11 EWM21950.1 - 1.8 8.7 13.4 1.1 9.4 11.3 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TMPIT PF07851.13 EWM21950.1 - 2.7 7.2 7.0 4 6.6 7.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF3450 PF11932.8 EWM21950.1 - 4 6.7 11.4 7 5.9 11.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Ax_dynein_light PF10211.9 EWM21950.1 - 4.6 7.1 14.1 11 5.9 14.1 1.7 1 0 0 1 1 1 0 Axonemal dynein light chain T2SSF PF00482.23 EWM21950.1 - 5.6 6.9 6.9 15 5.6 6.6 1.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Muted PF14942.6 EWM21950.1 - 6.2 7.2 12.6 13 6.1 12.6 1.5 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein ABC_tran PF00005.27 EWM21951.1 - 1.6e-44 151.8 0.0 1e-20 74.7 0.0 3.2 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 EWM21951.1 - 3.7e-19 69.7 0.9 4.4e-05 23.4 0.1 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EWM21951.1 - 5.5e-10 39.1 0.0 0.038 13.4 0.0 3.8 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EWM21951.1 - 5.7e-09 35.6 0.2 0.00043 20.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_tran_Xtn PF12848.7 EWM21951.1 - 4.7e-07 29.7 8.3 4.7e-07 29.7 8.3 2.9 3 0 0 3 3 2 1 ABC transporter AAA_13 PF13166.6 EWM21951.1 - 9.9e-07 27.8 3.8 0.0062 15.2 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 EWM21951.1 - 2.2e-06 28.3 0.0 0.00013 22.6 0.0 3.8 5 0 0 5 5 3 2 AAA domain AAA PF00004.29 EWM21951.1 - 4.5e-06 27.1 0.1 0.3 11.5 0.0 3.5 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EWM21951.1 - 5.2e-06 27.0 2.1 0.044 14.1 0.0 3.5 3 1 1 4 4 4 2 AAA ATPase domain RsgA_GTPase PF03193.16 EWM21951.1 - 6.3e-06 26.2 0.0 0.072 13.0 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 EWM21951.1 - 7.8e-06 25.8 7.3 0.011 15.5 0.2 3.8 3 1 0 3 3 3 2 AAA ATPase domain NACHT PF05729.12 EWM21951.1 - 1.1e-05 25.5 0.0 0.12 12.2 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 EWM21951.1 - 1.8e-05 25.0 0.0 0.1 12.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EWM21951.1 - 0.00016 21.9 0.1 0.23 11.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 EWM21951.1 - 0.00022 21.6 0.0 0.59 10.6 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_30 PF13604.6 EWM21951.1 - 0.00029 20.6 0.2 0.26 11.0 0.0 3.5 4 0 0 4 4 3 1 AAA domain AAA_24 PF13479.6 EWM21951.1 - 0.00031 20.5 0.1 0.29 10.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 EWM21951.1 - 0.00075 20.1 0.5 0.44 11.1 0.0 3.8 4 0 0 4 4 3 1 AAA domain AAA_28 PF13521.6 EWM21951.1 - 0.00078 19.7 7.6 0.13 12.5 0.0 3.4 4 0 0 4 4 2 2 AAA domain cobW PF02492.19 EWM21951.1 - 0.0011 18.5 0.0 2.2 7.8 0.0 2.6 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 EWM21951.1 - 0.0016 18.4 0.0 2.8 8.0 0.0 3.1 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EWM21951.1 - 0.0031 17.6 0.9 0.3 11.2 0.1 2.9 3 0 0 3 3 2 1 50S ribosome-binding GTPase NB-ARC PF00931.22 EWM21951.1 - 0.0036 16.5 0.0 2.1 7.5 0.0 2.8 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.15 EWM21951.1 - 0.0037 17.2 0.4 0.88 9.5 0.1 2.6 2 0 0 2 2 2 1 NTPase AAA_5 PF07728.14 EWM21951.1 - 0.0051 16.8 0.8 0.48 10.4 0.1 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 EWM21951.1 - 0.0059 16.5 1.4 4.2 7.2 0.0 3.0 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 EWM21951.1 - 0.0065 16.0 0.0 4 6.9 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_25 PF13481.6 EWM21951.1 - 0.011 15.3 0.1 3 7.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 EWM21951.1 - 0.014 14.7 0.1 7.8 5.8 0.0 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Roc PF08477.13 EWM21951.1 - 0.016 15.4 0.0 6.9 6.9 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Spt20 PF12090.8 EWM21951.1 - 0.035 13.7 1.1 0.063 12.9 1.1 1.3 1 0 0 1 1 1 0 Spt20 family AAA_27 PF13514.6 EWM21951.1 - 0.04 13.5 2.4 2.3 7.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 EWM21951.1 - 0.044 12.8 0.0 2.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein SRP54 PF00448.22 EWM21951.1 - 0.055 13.1 0.2 6.6 6.3 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.9 EWM21951.1 - 0.058 13.1 0.1 13 5.5 0.0 2.7 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation SbcCD_C PF13558.6 EWM21951.1 - 0.064 13.5 0.0 4.4 7.6 0.1 3.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit dNK PF01712.19 EWM21951.1 - 0.078 12.8 0.0 2 8.2 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase TsaE PF02367.17 EWM21951.1 - 0.1 12.6 0.0 21 5.1 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MobB PF03205.14 EWM21951.1 - 0.13 12.1 4.6 11 5.9 0.0 3.7 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.23 EWM21951.1 - 0.14 12.2 0.7 11 6.0 0.0 3.1 3 0 0 3 3 3 0 Dynamin family DUF3987 PF13148.6 EWM21951.1 - 0.16 10.9 0.0 0.16 10.9 0.0 4.2 5 0 0 5 5 5 0 Protein of unknown function (DUF3987) ATP_bind_1 PF03029.17 EWM21951.1 - 0.6 9.8 2.4 4.4 7.0 0.0 2.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein SUZ PF12752.7 EWM21951.1 - 5.8 7.8 9.2 16 6.3 0.8 2.7 2 1 0 2 2 2 0 SUZ domain SpoU_methylase PF00588.19 EWM21952.1 - 1.4e-28 99.8 0.1 2.6e-28 99.0 0.0 1.5 2 0 0 2 2 2 1 SpoU rRNA Methylase family Mito_carr PF00153.27 EWM21953.1 - 3.2e-49 164.8 3.3 9.8e-23 79.9 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EWM21953.1 - 0.03 13.5 0.5 8.6 5.4 0.0 3.2 3 1 0 3 3 3 0 Gammaproteobacterial serine protease PRK PF00485.18 EWM21954.1 - 5.1e-64 215.7 0.0 7.8e-64 215.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 EWM21954.1 - 0.033 14.6 0.0 0.16 12.3 0.0 2.3 1 1 0 1 1 1 0 AAA ATPase domain Colicin_E5 PF12106.8 EWM21954.1 - 0.065 13.5 0.2 0.15 12.4 0.2 1.6 1 0 0 1 1 1 0 Colicin E5 ribonuclease domain TLD PF07534.16 EWM21955.1 - 2e-06 28.1 0.0 2.6e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 TLD PH PF00169.29 EWM21958.1 - 0.0011 19.5 0.0 0.0022 18.5 0.0 1.5 1 0 0 1 1 1 1 PH domain Mito_carr PF00153.27 EWM21959.1 - 0.00021 21.2 0.5 0.00032 20.6 0.5 1.3 1 1 0 1 1 1 1 Mitochondrial carrier protein COX6B PF02297.17 EWM21962.1 - 0.0027 17.9 0.2 0.0043 17.3 0.2 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 EWM21962.1 - 0.0057 16.6 1.4 0.026 14.6 0.3 2.0 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 EWM21962.1 - 0.036 14.2 2.6 0.57 10.4 0.4 2.2 2 0 0 2 2 2 0 CHCH domain UPF0203 PF05254.12 EWM21962.1 - 0.25 11.6 1.9 0.52 10.6 1.9 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) TetR_C_15 PF17918.1 EWM21964.1 - 0.038 14.7 0.1 0.061 14.1 0.1 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain UAF_Rrn10 PF05234.11 EWM21964.1 - 0.068 13.4 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 UAF complex subunit Rrn10 QWRF PF04484.12 EWM21964.1 - 2.4 7.8 7.1 5.9 6.6 5.0 2.0 2 0 0 2 2 2 0 QWRF family Hamartin PF04388.12 EWM21964.1 - 4.3 5.9 9.9 5.4 5.6 9.9 1.1 1 0 0 1 1 1 0 Hamartin protein Na_H_Exchanger PF00999.21 EWM21966.1 - 6.1e-60 203.0 42.0 7.6e-60 202.7 42.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Glycos_transf_1 PF00534.20 EWM21967.1 - 1.4e-18 67.1 0.0 2.3e-16 59.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EWM21967.1 - 2.6e-11 44.1 0.0 7.8e-11 42.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EWM21967.1 - 6.4e-08 32.9 0.0 2.2e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 SMG1_N PF17229.2 EWM21967.1 - 0.32 11.7 1.3 29 5.5 0.1 2.4 2 0 0 2 2 2 0 Serine/threonine-protein kinase SMG1 N-terminal GTP_EFTU PF00009.27 EWM21968.1 - 1.1e-39 135.9 0.0 1.8e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EWM21968.1 - 4.9e-15 55.8 0.0 9.2e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EWM21968.1 - 0.00013 22.2 0.8 0.0004 20.7 0.8 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EWM21968.1 - 0.0038 17.3 0.0 0.1 12.7 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase HBS1_N PF08938.10 EWM21968.1 - 0.041 14.2 1.0 9.6 6.6 0.0 2.3 2 0 0 2 2 2 0 HBS1 N-terminus PBP1_TM PF14812.6 EWM21968.1 - 0.051 13.9 4.7 0.14 12.5 4.7 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HIT PF01230.23 EWM21969.1 - 1.4e-25 89.8 0.1 2.4e-25 89.1 0.1 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EWM21969.1 - 2.7e-20 73.0 0.0 4.4e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GST_N_3 PF13417.6 EWM21969.1 - 3.5e-11 43.3 0.0 6.1e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EWM21969.1 - 6.8e-08 32.7 0.0 1.4e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EWM21969.1 - 1.9e-05 24.8 0.0 4.1e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EWM21969.1 - 3.4e-05 23.8 0.1 9.5e-05 22.4 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EWM21969.1 - 0.0006 20.0 0.2 0.0033 17.6 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EWM21969.1 - 0.0096 16.1 0.1 0.023 14.9 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EWM21969.1 - 0.079 13.5 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Na_H_Exchanger PF00999.21 EWM21970.1 - 3e-60 204.0 42.7 3.6e-60 203.8 42.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Aspzincin_M35 PF14521.6 EWM21973.1 - 0.025 15.1 1.6 0.11 13.1 0.1 2.6 2 0 0 2 2 2 0 Lysine-specific metallo-endopeptidase Mce4_CUP1 PF11887.8 EWM21973.1 - 0.048 13.1 0.1 0.092 12.2 0.1 1.4 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative Syntaxin_2 PF14523.6 EWM21973.1 - 0.13 12.6 3.2 8.2 6.9 0.4 2.5 2 0 0 2 2 2 0 Syntaxin-like protein E1_DerP2_DerF2 PF02221.15 EWM21974.1 - 7.4e-10 39.4 0.0 1.1e-09 38.8 0.0 1.2 1 0 0 1 1 1 1 ML domain DUF4150 PF13665.6 EWM21975.1 - 0.3 11.3 0.9 0.78 9.9 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4150) OpgC_C PF10129.9 EWM21977.1 - 0.071 12.0 0.0 0.077 11.9 0.0 1.0 1 0 0 1 1 1 0 OpgC protein Sigma54_AID PF00309.20 EWM21977.1 - 0.19 11.6 1.0 0.38 10.7 1.0 1.5 1 0 0 1 1 1 0 Sigma-54 factor, Activator interacting domain (AID) Ammonium_transp PF00909.21 EWM21983.1 - 2.5e-16 59.4 0.6 2.7e-16 59.3 0.6 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family PT PF04886.12 EWM21985.1 - 9.1e-08 31.5 146.2 0.0031 17.0 23.7 5.6 1 1 4 5 5 5 4 PT repeat SPX PF03105.19 EWM21990.1 - 0.74 9.7 10.6 0.87 9.4 10.6 1.2 1 0 0 1 1 1 0 SPX domain ABC_membrane PF00664.23 EWM21991.1 - 1.8e-29 103.2 0.5 2.7e-29 102.7 0.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_membrane PF00664.23 EWM21992.1 - 5.1e-13 49.3 0.4 7.2e-13 48.8 0.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region NUDIX PF00293.28 EWM21993.1 - 3.8e-14 52.8 0.5 5.8e-14 52.3 0.1 1.5 2 0 0 2 2 2 1 NUDIX domain NUDIX PF00293.28 EWM21994.1 - 2.8e-14 53.3 0.1 3.5e-14 53.0 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain CS PF04969.16 EWM21996.1 - 1.4e-05 26.0 0.0 2.4e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 CS domain CDC37_N PF03234.14 EWM21996.1 - 3.2e-05 24.8 0.6 5.3e-05 24.1 0.6 1.3 1 0 0 1 1 1 1 Cdc37 N terminal kinase binding Rotamase_3 PF13616.6 EWM21998.1 - 6.6e-09 36.3 0.0 1e-08 35.7 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 EWM21998.1 - 1e-06 29.6 0.0 1.6e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain MNHE PF01899.16 EWM21998.1 - 0.0079 16.0 0.3 0.012 15.3 0.2 1.3 1 1 0 1 1 1 1 Na+/H+ ion antiporter subunit Rhodanese PF00581.20 EWM21999.1 - 3.5e-12 46.8 0.0 5.1e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain NinE PF05322.11 EWM22001.1 - 0.18 11.7 0.4 0.96 9.4 0.1 2.0 1 1 1 2 2 2 0 NINE Protein ALMS_repeat PF18727.1 EWM22002.1 - 0.12 12.3 0.4 0.23 11.4 0.4 1.4 1 0 0 1 1 1 0 Alstrom syndrome repeat Pou PF00157.17 EWM22002.1 - 0.13 12.2 0.2 0.23 11.5 0.2 1.3 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain Invasin_D3 PF09134.10 EWM22002.1 - 2.6 8.4 5.6 3e+02 1.8 5.6 2.4 1 1 0 1 1 1 0 Invasin, domain 3 DUF4357 PF14267.6 EWM22003.1 - 0.31 11.0 0.1 0.31 11.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4357) ALMS_repeat PF18727.1 EWM22004.1 - 0.083 12.8 0.4 0.16 11.9 0.4 1.4 1 0 0 1 1 1 0 Alstrom syndrome repeat Pou PF00157.17 EWM22004.1 - 0.1 12.6 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain Invasin_D3 PF09134.10 EWM22004.1 - 1.5 9.2 6.0 2.4e+02 2.1 6.0 2.4 1 1 0 1 1 1 0 Invasin, domain 3 Ste5 PF11610.8 EWM22005.1 - 0.11 12.4 0.2 0.24 11.3 0.2 1.6 1 0 0 1 1 1 0 Scaffold protein Ste5, Fus3-binding region V_ATPase_I PF01496.19 EWM22007.1 - 7.6e-58 196.1 0.0 1.7e-34 118.9 0.0 2.0 2 0 0 2 2 2 2 V-type ATPase 116kDa subunit family V_ATPase_I PF01496.19 EWM22008.1 - 5e-15 54.5 0.1 5.1e-15 54.5 0.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family BBP1_C PF15272.6 EWM22008.1 - 0.095 12.5 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Chloroa_b-bind PF00504.21 EWM22009.1 - 1.5e-24 87.4 0.0 2.3e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Fasciclin PF02469.22 EWM22009.1 - 8.8e-19 68.0 0.0 1.4e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain DUF4381 PF14316.6 EWM22009.1 - 0.07 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF4448 PF14610.6 EWM22010.1 - 0.082 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Ank_2 PF12796.7 EWM22011.1 - 8.8e-21 74.3 0.4 3.2e-10 40.5 0.0 3.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EWM22011.1 - 4.7e-17 61.6 9.8 0.00024 21.4 0.0 5.7 5 1 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 EWM22011.1 - 1.9e-15 55.4 2.3 0.0078 16.6 0.0 5.8 4 2 1 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 EWM22011.1 - 2.6e-13 50.2 9.8 9.3e-07 29.3 0.3 4.6 4 1 0 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EWM22011.1 - 2.6e-12 46.7 7.6 0.0032 17.7 0.0 4.8 3 1 2 5 5 5 4 Ankyrin repeats (many copies) UPF0061 PF02696.14 EWM22014.1 - 3.3e-13 49.2 0.0 3.4e-13 49.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Exo_endo_phos PF03372.23 EWM22015.1 - 1.3e-05 24.8 0.0 2.2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PGAP1 PF07819.13 EWM22016.1 - 3.5e-07 30.2 0.0 5.3e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 EWM22016.1 - 0.0046 16.8 0.0 0.0065 16.3 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_3 PF01764.25 EWM22016.1 - 0.0067 16.3 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 EWM22016.1 - 0.015 14.6 0.0 3.5 6.8 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EWM22016.1 - 0.031 14.9 10.1 0.075 13.6 10.1 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.14 EWM22016.1 - 0.16 11.4 0.0 0.25 10.8 0.0 1.1 1 0 0 1 1 1 0 Putative serine esterase (DUF676) UPF0061 PF02696.14 EWM22018.1 - 7.1e-21 74.5 0.0 9.1e-21 74.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family RRM_1 PF00076.22 EWM22019.1 - 9.4e-10 38.2 0.0 1.5e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 4HBT_3 PF13622.6 EWM22020.1 - 1.4e-22 81.2 0.1 2.4e-22 80.4 0.1 1.4 1 1 0 1 1 1 1 Thioesterase-like superfamily EF-hand_7 PF13499.6 EWM22021.1 - 1.6e-08 34.8 2.6 2.3e-08 34.3 2.1 1.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EWM22021.1 - 7.3e-08 32.1 0.5 1.1e-07 31.6 0.5 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EWM22021.1 - 2.1e-06 26.9 4.8 0.0069 15.9 1.5 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EWM22021.1 - 1.3e-05 24.8 4.1 0.008 16.0 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain HSP20 PF00011.21 EWM22022.1 - 1.1e-22 80.1 0.4 1.3e-22 79.9 0.4 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EWM22022.1 - 4.3e-07 29.4 0.0 7.3e-07 28.6 0.0 1.4 1 1 0 1 1 1 1 HSP20-like domain found in ArsA AAA_lid_9 PF17871.1 EWM22023.1 - 2.6e-36 123.7 1.2 2.6e-36 123.7 1.2 2.0 1 1 1 2 2 2 1 AAA lid domain EzrA PF06160.12 EWM22023.1 - 0.00059 18.1 4.4 0.00077 17.8 4.4 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA V-SNARE PF05008.15 EWM22023.1 - 0.013 15.9 3.1 0.013 15.9 3.1 2.5 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Cyclin_N PF00134.23 EWM22023.1 - 0.15 11.8 0.1 0.15 11.8 0.1 1.7 2 0 0 2 2 2 0 Cyclin, N-terminal domain FlaC_arch PF05377.11 EWM22023.1 - 1.3 9.5 5.4 18 5.8 0.2 2.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF16 PF01519.16 EWM22023.1 - 2.2 8.8 7.0 0.37 11.3 1.8 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 AAA_2 PF07724.14 EWM22024.1 - 4.8e-52 176.5 0.0 9.3e-52 175.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.9 EWM22024.1 - 2.6e-20 72.3 0.4 7.4e-20 70.8 0.4 1.8 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 EWM22024.1 - 3.1e-12 46.7 0.0 1.2e-11 44.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EWM22024.1 - 4.7e-11 43.2 0.0 1e-10 42.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EWM22024.1 - 4e-07 29.9 0.2 8.8e-07 28.8 0.0 1.7 2 0 0 2 2 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 EWM22024.1 - 5.8e-06 26.8 0.4 3e-05 24.5 0.4 2.3 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 EWM22024.1 - 0.00034 20.4 0.0 0.00082 19.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 EWM22024.1 - 0.00055 20.2 0.1 0.0037 17.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain DNA_pol3_delta2 PF13177.6 EWM22024.1 - 0.00078 19.3 0.0 0.004 17.0 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit DUF87 PF01935.17 EWM22024.1 - 0.0015 18.7 0.0 0.0034 17.5 0.0 1.6 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_7 PF12775.7 EWM22024.1 - 0.0023 17.5 0.0 0.0044 16.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 EWM22024.1 - 0.0026 17.8 0.0 0.009 16.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EWM22024.1 - 0.0033 16.7 0.0 0.0061 15.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin RNA_helicase PF00910.22 EWM22024.1 - 0.0086 16.5 0.1 0.03 14.7 0.0 1.9 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 EWM22024.1 - 0.0086 16.6 0.0 0.021 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EWM22024.1 - 0.0087 16.6 0.0 0.017 15.6 0.0 1.7 1 1 0 1 1 1 1 ABC transporter DUF815 PF05673.13 EWM22024.1 - 0.013 14.6 0.0 0.023 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) T2SSE PF00437.20 EWM22024.1 - 0.015 14.4 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Mg_chelatase PF01078.21 EWM22024.1 - 0.018 14.4 0.2 0.38 10.1 0.0 2.4 1 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 EWM22024.1 - 0.019 14.9 0.0 0.14 12.0 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase RuvB_N PF05496.12 EWM22024.1 - 0.021 14.5 0.0 0.083 12.6 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EWM22024.1 - 0.028 14.6 0.1 0.08 13.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain DUF5397 PF17375.2 EWM22024.1 - 0.058 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5397) AAA_23 PF13476.6 EWM22024.1 - 0.058 13.9 0.0 0.13 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain Torsin PF06309.11 EWM22024.1 - 0.07 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Torsin Roc PF08477.13 EWM22024.1 - 0.075 13.2 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 EWM22024.1 - 0.082 12.8 0.0 1.2 8.9 0.0 2.1 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea TIP49 PF06068.13 EWM22024.1 - 0.11 11.6 0.0 0.25 10.5 0.0 1.6 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_PrkA PF08298.11 EWM22024.1 - 0.14 11.0 0.0 2.3 7.0 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain ResIII PF04851.15 EWM22024.1 - 0.19 11.7 0.0 0.51 10.3 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Ser_hydrolase PF06821.13 EWM22025.1 - 1.4e-10 41.3 0.0 1.9e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_6 PF12697.7 EWM22025.1 - 7.1e-06 26.8 0.9 9.7e-06 26.3 0.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EWM22025.1 - 0.00029 20.6 0.7 0.037 13.7 0.5 2.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF1057 PF06342.12 EWM22025.1 - 0.0037 16.3 0.0 0.0054 15.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Hydrolase_4 PF12146.8 EWM22025.1 - 0.031 13.5 0.1 0.066 12.5 0.1 1.4 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Ndr PF03096.14 EWM22025.1 - 0.098 11.3 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Ndr family Abhydrolase_4 PF08386.10 EWM22025.1 - 0.12 12.5 0.0 0.42 10.7 0.0 1.9 2 0 0 2 2 2 0 TAP-like protein Polysacc_deac_1 PF01522.21 EWM22028.1 - 3.9e-09 36.5 0.0 6.2e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase PT PF04886.12 EWM22030.1 - 0.026 14.1 32.5 1.3 8.6 5.3 4.6 3 0 0 3 3 3 0 PT repeat SOG2 PF10428.9 EWM22030.1 - 9.3 5.3 12.8 17 4.4 12.8 1.5 1 0 0 1 1 1 0 RAM signalling pathway protein PT PF04886.12 EWM22031.1 - 0.023 14.2 32.5 1.3 8.6 5.3 4.6 3 0 0 3 3 3 0 PT repeat SOG2 PF10428.9 EWM22031.1 - 7.1 5.7 12.4 13 4.8 12.4 1.5 1 0 0 1 1 1 0 RAM signalling pathway protein Thioredoxin PF00085.20 EWM22032.1 - 3.3e-57 190.8 0.0 2e-30 104.8 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 EWM22032.1 - 1.7e-23 83.4 0.0 1.5e-16 60.8 0.0 3.6 3 1 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EWM22032.1 - 2.4e-12 46.9 0.0 1.1e-06 28.7 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EWM22032.1 - 3.1e-12 46.9 1.1 1.9e-06 28.3 0.0 4.0 3 2 0 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 EWM22032.1 - 2.8e-05 23.6 0.0 0.16 11.3 0.0 2.2 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EWM22032.1 - 5.7e-05 23.0 0.1 0.02 14.8 0.0 3.1 2 1 1 3 3 3 1 AhpC/TSA family Thioredoxin_8 PF13905.6 EWM22032.1 - 0.0014 18.9 0.0 1.4 9.3 0.0 3.1 3 1 0 3 3 3 2 Thioredoxin-like Thioredoxin PF00085.20 EWM22033.1 - 2.2e-24 85.4 0.0 4e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.6 EWM22033.1 - 2e-18 67.0 0.1 8.1e-17 61.7 0.0 2.7 2 1 1 3 3 3 1 Thioredoxin-like domain Thioredoxin_2 PF13098.6 EWM22033.1 - 0.0022 18.4 0.5 0.075 13.5 0.3 2.9 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EWM22033.1 - 0.0039 17.3 0.0 0.012 15.8 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin-like TauE PF01925.19 EWM22034.1 - 5.2e-16 59.0 18.6 5.2e-16 59.0 18.6 2.0 1 1 1 2 2 2 2 Sulfite exporter TauE/SafE Ribosomal_L32e PF01655.18 EWM22035.1 - 3.4e-47 159.3 0.3 4e-47 159.1 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Exo_endo_phos PF03372.23 EWM22036.1 - 3.1e-09 36.7 0.0 2.6e-08 33.7 0.0 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family YoaP PF14268.6 EWM22036.1 - 0.15 11.6 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 YoaP-like DUF1843 PF08898.10 EWM22036.1 - 0.16 12.5 0.2 1 9.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) SQS_PSY PF00494.19 EWM22037.1 - 5.6e-66 222.7 0.6 8.5e-66 222.1 0.6 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase SOG2 PF10428.9 EWM22037.1 - 0.028 13.6 3.5 0.038 13.2 3.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein RNA_pol_Rpb2_6 PF00562.28 EWM22038.1 - 5.7e-114 381.2 0.0 1.7e-113 379.6 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EWM22038.1 - 9.2e-28 97.1 0.0 1.5e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 EWM22038.1 - 1.6e-26 92.3 0.0 3.2e-26 91.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 EWM22038.1 - 2.8e-19 69.3 0.1 1.1e-18 67.4 0.1 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 EWM22038.1 - 7.1e-19 68.2 0.0 1.1e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 EWM22038.1 - 1.2e-11 44.4 0.0 2.8e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain DUF1086 PF06461.11 EWM22039.1 - 0.038 13.8 0.0 6.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1086) DIL PF01843.19 EWM22039.1 - 0.15 12.3 0.7 35 4.7 0.1 3.2 3 0 0 3 3 3 0 DIL domain Peptidase_S24 PF00717.23 EWM22040.1 - 0.00045 20.1 0.8 0.007 16.3 0.5 2.5 2 1 0 2 2 2 1 Peptidase S24-like MTS PF05175.14 EWM22042.1 - 2.1e-10 40.4 0.0 4e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EWM22042.1 - 4.5e-10 39.5 0.0 7.5e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM22042.1 - 8.2e-08 32.9 0.0 1.8e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EWM22042.1 - 1.2e-05 25.1 0.0 1.7e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PrmA PF06325.13 EWM22042.1 - 1.2e-05 24.8 0.3 1.8e-05 24.3 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) N6_Mtase PF02384.16 EWM22042.1 - 0.0003 20.2 0.0 0.00039 19.8 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_12 PF08242.12 EWM22042.1 - 0.0004 21.1 0.0 0.0015 19.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 EWM22042.1 - 0.0012 18.6 0.0 0.0017 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 EWM22042.1 - 0.0013 19.3 0.0 0.0033 18.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 EWM22042.1 - 0.002 17.8 0.3 0.013 15.2 0.3 2.0 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 AviRa PF11599.8 EWM22042.1 - 0.0046 16.4 0.8 0.0078 15.7 0.7 1.4 1 1 0 1 1 1 1 RRNA methyltransferase AviRa Methyltransf_32 PF13679.6 EWM22042.1 - 0.14 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CDV3 PF15359.6 EWM22043.1 - 0.13 12.8 0.3 0.13 12.8 0.3 1.5 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 CDC27 PF09507.10 EWM22044.1 - 3.4e-08 33.3 35.3 0.00015 21.3 0.1 2.9 2 1 0 2 2 2 2 DNA polymerase subunit Cdc27 RCDG1 PF15725.5 EWM22044.1 - 1.1 9.7 4.2 0.3 11.5 0.4 2.0 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein Methyltransf_25 PF13649.6 EWM22045.1 - 1.3e-10 41.8 0.1 2.2e-05 25.1 0.1 2.6 2 0 0 2 2 2 2 Methyltransferase domain PrmA PF06325.13 EWM22045.1 - 1e-07 31.7 0.5 2.1e-07 30.6 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EWM22045.1 - 5.8e-07 30.1 0.0 0.026 15.2 0.1 2.5 2 0 0 2 2 2 2 Methyltransferase domain Ank_5 PF13857.6 EWM22045.1 - 2.3e-06 27.8 0.1 1e-05 25.7 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Methyltransf_31 PF13847.6 EWM22045.1 - 3.8e-06 26.8 0.0 0.0085 15.9 0.0 2.6 3 0 0 3 3 3 2 Methyltransferase domain Ank_2 PF12796.7 EWM22045.1 - 1.1e-05 25.9 0.2 3.1e-05 24.5 0.2 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Methyltransf_24 PF13578.6 EWM22045.1 - 2.3e-05 25.3 0.0 0.47 11.5 0.0 3.0 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EWM22045.1 - 0.0016 19.1 0.0 0.09 13.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EWM22045.1 - 0.0023 17.8 0.0 0.055 13.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EWM22045.1 - 0.0079 15.8 0.3 0.026 14.1 0.2 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.7 EWM22045.1 - 0.01 15.8 0.1 0.022 14.7 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 EWM22045.1 - 0.017 14.3 0.0 3.4 6.8 0.0 2.4 2 0 0 2 2 2 0 O-methyltransferase Ank PF00023.30 EWM22045.1 - 0.024 15.1 0.2 0.17 12.4 0.1 2.7 2 0 0 2 2 1 0 Ankyrin repeat Cons_hypoth95 PF03602.15 EWM22045.1 - 0.024 14.3 0.1 0.25 11.0 0.1 2.2 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Ank_4 PF13637.6 EWM22045.1 - 0.054 14.1 0.0 0.17 12.5 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeats (many copies) RrnaAD PF00398.20 EWM22045.1 - 0.081 12.0 0.0 0.83 8.7 0.0 2.0 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Ank_3 PF13606.6 EWM22045.1 - 0.14 12.8 0.6 1.6 9.5 0.1 3.0 3 0 0 3 3 2 0 Ankyrin repeat SWIB PF02201.18 EWM22046.1 - 1.8e-30 104.6 0.1 2.5e-30 104.1 0.1 1.2 1 0 0 1 1 1 1 SWIB/MDM2 domain Methyltransf_16 PF10294.9 EWM22047.1 - 6.8e-10 38.9 0.0 1e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 EWM22047.1 - 1.2e-08 35.5 0.0 2.4e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EWM22047.1 - 0.00011 22.0 0.0 0.00017 21.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM22047.1 - 0.0003 20.6 0.0 0.0005 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM22047.1 - 0.0014 19.2 0.0 0.0034 18.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EWM22047.1 - 0.0046 16.4 0.0 0.0064 15.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 EWM22047.1 - 0.01 16.5 0.0 0.023 15.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EWM22047.1 - 0.028 14.0 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Cons_hypoth95 PF03602.15 EWM22047.1 - 0.11 12.1 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 GidB PF02527.15 EWM22047.1 - 0.16 11.2 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_18 PF12847.7 EWM22047.1 - 0.17 11.8 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain APC1_C PF18122.1 EWM22048.1 - 1.5e-42 145.4 0.0 2.2e-42 144.9 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex sub unit 1 C-terminal domain CxxCxxCC PF03692.15 EWM22049.1 - 2.5e-07 31.3 7.2 9.8e-06 26.2 8.7 2.2 1 1 1 2 2 2 1 Putative zinc- or iron-chelating domain DUF4775 PF16001.5 EWM22049.1 - 0.16 11.4 2.9 5.2 6.4 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4775) Patatin PF01734.22 EWM22050.1 - 1.2e-12 48.4 0.1 2.7e-05 24.4 0.0 2.4 2 0 0 2 2 2 2 Patatin-like phospholipase DER1 PF04511.15 EWM22051.1 - 2.6e-26 92.8 0.6 3.5e-26 92.3 0.6 1.2 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.22 EWM22051.1 - 0.067 13.2 0.9 0.11 12.4 0.9 1.5 1 1 0 1 1 1 0 Rhomboid family MIP PF00230.20 EWM22052.1 - 9.1e-46 156.4 13.3 1.1e-45 156.1 13.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein H2TH PF06831.14 EWM22053.1 - 6.2e-23 80.6 0.0 9.8e-23 80.0 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.24 EWM22053.1 - 0.0013 19.4 0.0 0.0024 18.5 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain FbpA PF05833.11 EWM22053.1 - 0.29 9.9 0.0 0.39 9.4 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) ArfGap PF01412.18 EWM22055.1 - 4.1e-36 123.6 0.0 6.7e-36 122.9 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ank_2 PF12796.7 EWM22055.1 - 0.00023 21.7 0.0 0.00055 20.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EWM22055.1 - 0.001 19.6 0.1 0.0089 16.6 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EWM22055.1 - 0.025 14.9 0.1 0.062 13.7 0.1 1.7 1 1 0 1 1 1 0 Ankyrin repeats (many copies) PH PF00169.29 EWM22055.1 - 0.13 12.7 0.3 0.23 12.0 0.3 1.4 1 0 0 1 1 1 0 PH domain HD PF01966.22 EWM22056.1 - 8.5e-05 22.8 0.0 0.00033 20.9 0.0 2.0 1 1 0 1 1 1 1 HD domain RIO1 PF01163.22 EWM22057.1 - 5.7e-47 159.8 0.2 8.4e-47 159.2 0.2 1.3 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 EWM22057.1 - 4.1e-34 116.7 0.3 7.3e-34 115.8 0.3 1.4 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 EWM22057.1 - 2.3e-09 37.5 0.8 0.00028 20.9 0.1 2.9 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EWM22057.1 - 1.3e-06 28.0 0.2 3.2e-05 23.4 0.2 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EWM22057.1 - 0.035 13.0 0.0 0.045 12.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 EWM22057.1 - 0.12 11.8 0.2 0.31 10.4 0.2 1.8 1 1 0 1 1 1 0 Protein kinase domain Pkinase PF00069.25 EWM22058.1 - 2.9e-30 105.5 0.0 1.5e-26 93.3 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EWM22058.1 - 1.6e-07 30.9 0.0 3e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 EWM22058.1 - 0.17 11.4 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Nop14 PF04147.12 EWM22059.1 - 3.8e-172 574.7 0.1 4.6e-172 574.4 0.1 1.0 1 0 0 1 1 1 1 Nop14-like family DIRP PF06584.13 EWM22059.1 - 0.79 9.9 4.0 2.3 8.4 4.0 1.8 1 0 0 1 1 1 0 DIRP GATase_5 PF13507.6 EWM22060.1 - 4.7e-85 284.8 0.0 6.6e-85 284.3 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 EWM22060.1 - 7.9e-30 104.1 1.5 4.6e-14 52.8 1.1 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain DUF1604 PF07713.13 EWM22060.1 - 0.13 12.1 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1604) DnaJ PF00226.31 EWM22061.1 - 1.4e-16 60.3 0.0 2.9e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain PseudoU_synth_2 PF00849.22 EWM22063.1 - 2.4e-14 53.7 0.0 1.3e-13 51.4 0.0 2.0 1 1 0 1 1 1 1 RNA pseudouridylate synthase PHD PF00628.29 EWM22064.1 - 9.7e-08 31.8 10.5 9.7e-08 31.8 10.5 1.7 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 EWM22064.1 - 3.3e-07 29.7 1.6 3.3e-07 29.7 1.6 2.0 2 0 0 2 2 2 1 PHD-finger Myb_DNA-binding PF00249.31 EWM22064.1 - 7.7e-07 29.2 0.0 1.9e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EWM22064.1 - 0.0043 16.9 0.2 0.0088 15.9 0.2 1.5 1 0 0 1 1 1 1 Myb DNA-binding like zf-PHD-like PF15446.6 EWM22064.1 - 0.014 15.0 1.7 0.014 15.0 1.7 2.2 1 1 1 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-HC5HC2H PF13771.6 EWM22064.1 - 0.21 11.9 7.3 0.055 13.7 3.6 1.9 2 1 0 2 2 2 0 PHD-like zinc-binding domain Myb_DNA-bind_6 PF13921.6 EWM22064.1 - 0.21 11.9 0.6 0.44 10.8 0.6 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain C1_2 PF03107.16 EWM22064.1 - 0.3 11.4 13.7 0.031 14.6 4.8 2.8 3 0 0 3 3 3 0 C1 domain Ribosom_S30AE_C PF16321.5 EWM22065.1 - 1.4e-20 72.7 0.4 3.4e-20 71.5 0.2 1.8 2 0 0 2 2 2 1 Sigma 54 modulation/S30EA ribosomal protein C terminus Ribosomal_S30AE PF02482.19 EWM22065.1 - 2.2e-20 73.2 0.7 3.5e-20 72.6 0.7 1.3 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein PDGLE PF13190.6 EWM22066.1 - 0.009 15.9 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 PDGLE domain DEAD PF00270.29 EWM22067.1 - 1e-45 155.7 0.0 2.4e-45 154.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EWM22067.1 - 6.1e-33 113.5 0.0 1.8e-32 112.0 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EWM22067.1 - 0.0043 17.1 0.0 0.015 15.3 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EWM22067.1 - 0.029 13.7 0.0 0.029 13.7 0.0 2.5 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit UCH PF00443.29 EWM22068.1 - 5e-48 163.8 0.0 6.4e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EWM22068.1 - 3.5e-15 56.4 0.0 2.3e-10 40.6 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-Sec23_Sec24 PF04810.15 EWM22068.1 - 0.022 14.8 0.7 0.07 13.2 0.0 2.2 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger BUD22 PF09073.10 EWM22068.1 - 0.18 11.1 0.1 0.3 10.4 0.1 1.2 1 0 0 1 1 1 0 BUD22 FYVE PF01363.21 EWM22069.1 - 7.1e-15 54.9 10.5 2.7e-14 53.0 10.5 2.1 1 1 0 1 1 1 1 FYVE zinc finger DUF4710 PF15828.5 EWM22069.1 - 0.012 15.7 0.2 0.86 9.8 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) FYVE_2 PF02318.16 EWM22069.1 - 0.058 13.6 8.9 0.13 12.5 8.0 1.9 1 1 0 1 1 1 0 FYVE-type zinc finger zinc-ribbons_6 PF07191.12 EWM22069.1 - 6.4 6.8 10.1 36 4.4 10.1 2.1 1 1 0 1 1 1 0 zinc-ribbons Pyr_redox_2 PF07992.14 EWM22070.1 - 1.4e-24 86.9 0.1 2e-24 86.4 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EWM22070.1 - 1.2e-12 48.1 0.0 5.9e-12 45.8 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EWM22070.1 - 1.2e-10 41.7 0.0 2.5e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EWM22070.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2808 PF10989.8 EWM22071.1 - 0.067 13.2 0.0 0.66 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2808) Ion_trans_2 PF07885.16 EWM22073.1 - 4.9e-13 48.9 5.7 1.5e-12 47.3 5.7 1.9 1 0 0 1 1 1 1 Ion channel BK_channel_a PF03493.18 EWM22073.1 - 2e-06 27.9 0.0 5.1e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.31 EWM22073.1 - 5.7e-06 25.7 18.5 6.2e-05 22.4 6.6 2.1 2 0 0 2 2 2 2 Ion transport protein Lig_chan PF00060.26 EWM22073.1 - 0.00097 19.0 0.8 0.0032 17.3 0.8 1.9 1 0 0 1 1 1 1 Ligand-gated ion channel CLP_protease PF00574.23 EWM22074.1 - 6.3e-79 264.1 0.1 7.8e-79 263.8 0.1 1.1 1 0 0 1 1 1 1 Clp protease ARGLU PF15346.6 EWM22075.1 - 1.7e-10 41.0 37.1 1.7e-10 41.0 37.1 2.1 2 0 0 2 2 2 1 Arginine and glutamate-rich 1 DUF763 PF05559.11 EWM22075.1 - 2.2 7.4 6.1 3.2 6.9 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Peptidase_C1 PF00112.23 EWM22076.1 - 5e-52 177.1 0.0 6.9e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EWM22076.1 - 1.6e-05 23.9 0.1 9e-05 21.4 0.1 1.9 2 0 0 2 2 2 1 Peptidase C1-like family DUF1206 PF06724.11 EWM22076.1 - 0.13 12.3 4.1 0.19 11.8 0.0 3.0 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1206) bZIP_1 PF00170.21 EWM22077.1 - 1.8e-08 34.4 13.6 1.8e-08 34.4 13.6 2.2 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 EWM22077.1 - 4.7e-07 29.8 25.1 1.7e-06 28.0 15.3 2.4 2 0 0 2 2 2 2 Basic region leucine zipper DUF2167 PF09935.9 EWM22077.1 - 0.035 13.3 0.4 0.061 12.5 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2167) BBS1 PF14779.6 EWM22077.1 - 0.11 11.9 3.2 0.15 11.5 3.2 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 DUF572 PF04502.13 EWM22077.1 - 0.42 10.2 24.6 0.56 9.8 24.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) TMEM214 PF10151.9 EWM22077.1 - 0.56 8.6 8.1 0.73 8.2 8.1 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator VPS38 PF17649.1 EWM22077.1 - 4.5 6.1 8.5 5.7 5.7 8.5 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting 38 bZIP_Maf PF03131.17 EWM22077.1 - 4.7 7.8 25.3 0.49 11.0 17.2 2.5 1 1 1 2 2 2 0 bZIP Maf transcription factor Myc_N PF01056.18 EWM22077.1 - 6 6.7 16.7 0.55 10.1 6.9 2.1 1 1 1 2 2 2 0 Myc amino-terminal region PGA2 PF07543.12 EWM22077.1 - 7.6 6.5 21.1 0.08 12.9 9.5 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 LAP1C PF05609.12 EWM22077.1 - 9.3 5.2 18.7 11 5.0 18.7 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Lipase_3 PF01764.25 EWM22078.1 - 5.8e-30 104.0 0.0 8.5e-30 103.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 EWM22078.1 - 0.00022 20.9 0.0 0.00096 18.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Thioesterase PF00975.20 EWM22078.1 - 0.00048 20.3 0.1 0.0015 18.7 0.1 1.8 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.7 EWM22078.1 - 0.004 17.8 0.2 0.0059 17.2 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EWM22078.1 - 0.12 11.7 0.1 0.2 10.9 0.1 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Esterase PF00756.20 EWM22078.1 - 0.12 12.0 0.2 0.29 10.7 0.1 1.6 2 0 0 2 2 2 0 Putative esterase PGAP1 PF07819.13 EWM22078.1 - 0.15 11.7 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein CLU_N PF15044.6 EWM22079.1 - 8e-07 29.3 0.1 1.6e-06 28.4 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term zf-ANAPC11 PF12861.7 EWM22080.1 - 3.4e-36 123.2 15.0 3.7e-36 123.1 15.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EWM22080.1 - 4.9e-20 71.6 17.6 7.1e-20 71.0 17.6 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EWM22080.1 - 4.3e-07 30.2 20.3 1.3e-05 25.4 20.3 2.2 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EWM22080.1 - 0.0053 16.7 13.6 0.0095 15.9 13.6 1.4 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.8 EWM22080.1 - 0.012 15.8 16.1 0.044 14.0 16.1 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4 PF00097.25 EWM22080.1 - 0.02 14.8 19.9 0.19 11.6 19.9 2.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EWM22080.1 - 0.026 14.5 16.7 0.17 11.9 16.7 2.1 1 1 0 1 1 1 0 zinc-RING finger domain Eaf7 PF07904.13 EWM22080.1 - 0.031 14.6 0.0 0.043 14.2 0.0 1.2 1 0 0 1 1 1 0 Chromatin modification-related protein EAF7 zf-RING_4 PF14570.6 EWM22080.1 - 0.036 13.9 3.1 0.036 13.9 3.1 2.4 1 1 0 2 2 2 0 RING/Ubox like zinc-binding domain GAGA PF09237.11 EWM22080.1 - 0.23 11.3 0.3 0.23 11.3 0.3 2.4 2 1 1 3 3 3 0 GAGA factor zf-Nse PF11789.8 EWM22080.1 - 0.35 10.7 7.3 0.66 9.8 7.3 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 EWM22080.1 - 0.85 9.4 15.1 8.7 6.2 15.1 2.4 1 1 0 1 1 1 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 EWM22080.1 - 1.1 9.2 22.6 1.4 8.9 16.1 3.0 1 1 1 2 2 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EWM22080.1 - 1.9 8.4 17.7 57 3.7 17.8 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 EWM22080.1 - 2.6 8.3 17.5 0.1 12.7 8.7 2.3 2 1 0 2 2 2 0 RING-variant domain GrpE PF01025.19 EWM22081.1 - 2.4e-43 147.7 1.2 2.9e-43 147.4 1.2 1.0 1 0 0 1 1 1 1 GrpE PorA PF11271.8 EWM22083.1 - 0.024 14.0 0.1 0.035 13.4 0.1 1.4 1 0 0 1 1 1 0 Porin PorA Gal_Lectin PF02140.18 EWM22083.1 - 2.5 8.6 4.8 0.71 10.3 0.2 2.6 3 1 1 4 4 4 0 Galactose binding lectin domain rRNA_processing PF08524.11 EWM22084.1 - 3.4e-17 62.8 8.6 1.2e-11 44.9 1.7 2.1 2 0 0 2 2 2 2 rRNA processing Myb_DNA-binding PF00249.31 EWM22086.1 - 1.3e-29 102.1 7.3 1.7e-16 60.1 0.3 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EWM22086.1 - 4.7e-22 78.0 1.8 2.8e-12 46.7 0.3 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain TFIIA PF03153.13 EWM22086.1 - 1.9e-07 31.4 17.2 1.9e-07 31.4 17.2 2.4 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit SANT_DAMP1_like PF16282.5 EWM22086.1 - 0.0002 21.5 0.2 0.094 12.9 0.1 2.4 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 EWM22086.1 - 0.00035 20.4 0.1 0.00035 20.4 0.1 3.2 2 1 1 3 3 2 1 Myb DNA-binding like Neur_chan_memb PF02932.16 EWM22086.1 - 0.23 11.5 4.4 0.47 10.5 4.4 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region UPF0560 PF10577.9 EWM22086.1 - 0.32 9.4 16.0 0.67 8.4 16.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 EPL1 PF10513.9 EWM22086.1 - 0.36 11.2 10.4 0.78 10.1 10.4 1.5 1 0 0 1 1 1 0 Enhancer of polycomb-like FHIPEP PF00771.20 EWM22086.1 - 0.37 9.2 1.8 0.56 8.6 1.8 1.2 1 0 0 1 1 1 0 FHIPEP family PAT1 PF09770.9 EWM22086.1 - 0.74 8.0 21.6 1 7.5 21.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Spt20 PF12090.8 EWM22086.1 - 1.6 8.3 35.1 2.7 7.5 35.1 1.3 1 0 0 1 1 1 0 Spt20 family SRRM_C PF15230.6 EWM22086.1 - 4.2 8.0 10.1 3.8 8.2 7.5 2.4 1 1 0 1 1 1 0 Serine/arginine repetitive matrix protein C-terminus SpoIIP PF07454.11 EWM22086.1 - 5.5 6.4 8.7 10 5.5 8.7 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) PRT_C PF08372.10 EWM22087.1 - 0.00021 21.1 0.2 0.00042 20.1 0.2 1.4 1 0 0 1 1 1 1 Plant phosphoribosyltransferase C-terminal Tombus_P19 PF03220.13 EWM22087.1 - 0.17 11.6 0.0 0.41 10.3 0.0 1.6 1 0 0 1 1 1 0 Tombusvirus P19 core protein Pex24p PF06398.11 EWM22087.1 - 0.23 10.4 1.5 0.56 9.1 0.6 1.4 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin SSF PF00474.17 EWM22089.1 - 6.3e-09 35.2 13.0 1.7e-08 33.7 11.8 2.2 1 1 0 1 1 1 1 Sodium:solute symporter family BSD PF03909.17 EWM22090.1 - 4.4e-07 29.8 4.5 1.1e-05 25.3 4.5 2.8 1 1 0 1 1 1 1 BSD domain ADIP PF11559.8 EWM22090.1 - 0.013 15.6 6.2 0.013 15.6 6.2 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.11 EWM22090.1 - 0.017 15.5 0.2 0.34 11.3 0.0 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) bZIP_1 PF00170.21 EWM22090.1 - 0.018 15.1 0.9 0.94 9.6 0.1 2.8 2 0 0 2 2 2 0 bZIP transcription factor Prefoldin PF02996.17 EWM22090.1 - 0.13 12.2 13.0 1.2 9.1 1.0 3.5 4 0 0 4 4 4 0 Prefoldin subunit Cnn_1N PF07989.11 EWM22090.1 - 0.2 11.8 5.9 0.32 11.2 0.6 2.7 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF4407 PF14362.6 EWM22090.1 - 1.8 7.8 13.4 0.28 10.5 7.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4201 PF13870.6 EWM22090.1 - 5.6 6.7 15.5 0.5 10.1 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) Peptidase_C26 PF07722.13 EWM22091.1 - 7.1e-17 61.9 0.0 1.2e-15 57.8 0.0 2.3 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 EWM22091.1 - 1e-10 41.7 0.0 1.5e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Formyl_trans_N PF00551.19 EWM22092.1 - 1.2e-35 122.8 0.0 2.6e-35 121.8 0.0 1.5 2 0 0 2 2 2 1 Formyl transferase Formyl_trans_C PF02911.18 EWM22092.1 - 1.4e-20 73.4 0.0 2.2e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain KH_1 PF00013.29 EWM22093.1 - 4.7e-65 215.3 10.1 8e-10 38.4 0.1 12.9 12 1 0 12 12 12 9 KH domain SLS PF14611.6 EWM22093.1 - 1.7e-16 60.7 0.9 0.052 13.4 0.1 7.8 4 2 3 7 7 7 5 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 EWM22093.1 - 3.4e-14 52.4 13.2 0.099 12.5 0.0 7.9 7 0 0 7 7 7 5 KH domain KH_4 PF13083.6 EWM22093.1 - 0.0003 20.6 11.3 0.048 13.5 0.1 6.2 7 0 0 7 7 7 3 KH domain GxGYxYP_N PF16216.5 EWM22094.1 - 1.1e-08 35.6 0.0 2.7e-08 34.2 0.0 1.7 1 1 0 1 1 1 1 GxGYxY sequence motif in domain of unknown function N-terminal Pyr_redox_2 PF07992.14 EWM22095.1 - 3.9e-06 26.3 0.0 4.6e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EWM22095.1 - 4.4e-06 26.3 0.1 5e-06 26.1 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EWM22095.1 - 2.3e-05 23.7 0.1 2.6e-05 23.5 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EWM22095.1 - 2.9e-05 23.4 0.0 4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 EWM22095.1 - 0.0011 17.7 0.4 0.0016 17.2 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 EWM22095.1 - 0.0037 16.4 0.1 0.0045 16.1 0.1 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EWM22095.1 - 0.017 15.3 0.1 0.029 14.6 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 EWM22095.1 - 0.069 12.4 0.2 0.099 11.9 0.2 1.4 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 EWM22095.1 - 1 8.5 2.4 1.5 8.0 2.4 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 EWM22096.1 - 6.7e-36 123.8 0.8 1.2e-35 123.1 0.8 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EWM22096.1 - 4e-25 88.4 0.2 9.7e-25 87.2 0.1 1.7 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 EWM22096.1 - 8.5e-07 29.1 0.0 2.1e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 EWM22096.1 - 3.2e-06 27.6 0.0 1e-05 26.0 0.0 1.9 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 EWM22096.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TPR_1 PF00515.28 EWM22097.1 - 2e-23 81.2 10.1 0.00016 21.3 0.0 6.0 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 EWM22097.1 - 3.1e-17 61.2 19.4 0.0035 17.3 0.1 6.0 6 0 0 6 6 5 5 Tetratricopeptide repeat RPAP3_C PF13877.6 EWM22097.1 - 4.1e-11 43.3 0.0 8.1e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_19 PF14559.6 EWM22097.1 - 8.9e-09 35.7 10.6 2e-05 25.0 0.6 4.7 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EWM22097.1 - 1.1e-08 35.6 22.0 0.017 15.8 1.1 5.7 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 EWM22097.1 - 1.4e-08 34.3 7.7 0.00017 21.2 0.1 4.8 3 2 2 5 5 5 3 TPR repeat TPR_7 PF13176.6 EWM22097.1 - 1.4e-07 31.0 2.7 0.41 10.8 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EWM22097.1 - 3.2e-07 30.5 12.0 0.18 12.1 0.1 5.0 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 EWM22097.1 - 1.6e-06 28.2 13.6 0.0041 17.2 1.1 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 EWM22097.1 - 1e-05 25.9 18.6 0.68 10.9 0.3 6.7 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 EWM22097.1 - 1.7e-05 24.9 5.7 0.069 13.6 0.0 5.3 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 EWM22097.1 - 3.6e-05 23.6 6.1 0.8 10.1 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 EWM22097.1 - 0.0056 17.2 10.4 19 6.1 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF3416 PF11896.8 EWM22097.1 - 0.024 15.0 6.5 0.11 12.7 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3416) TPR_10 PF13374.6 EWM22097.1 - 0.038 13.9 11.4 0.68 9.9 0.2 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF357 PF04010.13 EWM22097.1 - 0.093 12.8 0.3 1 9.5 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF357) Fis1_TPR_C PF14853.6 EWM22097.1 - 0.17 12.0 0.1 0.17 12.0 0.1 2.5 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat FAD_binding_4 PF01565.23 EWM22098.1 - 3e-23 82.1 0.0 5e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 EWM22098.1 - 3e-05 24.0 0.0 4.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase DUF3330 PF11809.8 EWM22098.1 - 0.18 11.9 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3330) SHMT PF00464.19 EWM22099.1 - 6.5e-204 677.0 0.0 7.8e-204 676.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 EWM22099.1 - 1.3e-08 34.4 0.0 3e-08 33.2 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EWM22099.1 - 0.06 12.7 0.0 0.16 11.2 0.0 1.7 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family mCpol PF18182.1 EWM22099.1 - 0.14 12.5 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 minimal CRISPR polymerase domain PRMT5 PF05185.16 EWM22102.1 - 1.6e-66 223.4 0.0 2.3e-66 222.9 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_TIM PF17285.2 EWM22102.1 - 1.9e-66 223.9 0.0 3.3e-66 223.1 0.0 1.4 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5_C PF17286.2 EWM22102.1 - 7.7e-57 192.0 2.8 1.1e-56 191.5 2.8 1.2 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_25 PF13649.6 EWM22102.1 - 0.00059 20.5 0.0 0.0016 19.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 EWM22102.1 - 0.001 18.8 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.6 EWM22102.1 - 0.029 14.2 0.0 0.065 13.0 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain DUF3447 PF11929.8 EWM22105.1 - 0.0076 16.2 0.3 0.013 15.5 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3447) ODV-E18 PF10717.9 EWM22105.1 - 0.026 14.4 1.1 0.048 13.5 1.1 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 CLU PF13236.6 EWM22106.1 - 9.6e-08 32.1 0.0 1.5e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Clustered mitochondria DUF4746 PF15928.5 EWM22106.1 - 0.26 10.7 3.1 0.29 10.5 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Nucleo_P87 PF07267.11 EWM22106.1 - 0.41 9.5 2.9 0.46 9.3 2.9 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SIR2 PF02146.17 EWM22107.1 - 2.4e-10 40.6 0.0 3.3e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 EWM22107.1 - 0.00069 19.4 0.0 0.001 18.8 0.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPR_12 PF13424.6 EWM22108.1 - 4.6e-13 49.3 14.4 1.8e-05 25.0 0.4 4.1 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 EWM22108.1 - 2.6e-08 33.5 2.3 0.029 14.2 0.5 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat eIF3_p135 PF12807.7 EWM22108.1 - 4.7e-06 26.7 0.0 6.5e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_14 PF13428.6 EWM22108.1 - 0.00067 20.3 12.8 0.33 11.9 0.2 5.7 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 EWM22108.1 - 0.0017 18.5 2.4 0.14 12.4 0.3 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EWM22108.1 - 0.025 14.7 11.3 0.69 10.2 0.5 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 EWM22108.1 - 0.076 13.7 1.1 79 4.3 0.0 4.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EWM22108.1 - 0.49 10.3 12.5 0.12 12.2 0.4 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EWM22108.1 - 5.3 7.5 7.7 4.9 7.6 0.6 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat ABC2_membrane PF01061.24 EWM22109.1 - 1.9e-28 99.3 14.7 3.7e-28 98.4 14.7 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EWM22109.1 - 2.5e-22 79.8 0.0 4e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EWM22109.1 - 8.9e-07 28.3 14.6 1.7e-06 27.4 14.6 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein SMC_N PF02463.19 EWM22109.1 - 0.00012 21.6 0.0 0.00036 20.1 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 EWM22109.1 - 0.0038 17.2 0.0 0.0063 16.5 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 EWM22109.1 - 0.0038 17.6 0.1 0.0091 16.4 0.0 1.7 2 0 0 2 2 1 1 AAA ATPase domain AAA_25 PF13481.6 EWM22109.1 - 0.0074 15.9 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF3533 PF12051.8 EWM22109.1 - 0.038 12.9 3.5 0.064 12.2 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) AAA_22 PF13401.6 EWM22109.1 - 0.048 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EWM22109.1 - 0.058 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase TMEM95 PF15203.6 EWM22109.1 - 0.13 11.9 0.5 14 5.3 0.0 2.5 3 0 0 3 3 3 0 TMEM95 family AAA_29 PF13555.6 EWM22109.1 - 0.18 11.6 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PrgI PF12666.7 EWM22109.1 - 6.4 7.6 9.9 0.78 10.5 4.5 2.3 1 1 1 2 2 2 0 PrgI family protein RNR_Alpha PF17975.1 EWM22110.1 - 5.4e-41 139.2 0.1 2.6e-40 137.0 0.1 2.2 2 0 0 2 2 2 1 Ribonucleotide reductase alpha domain Ribonuc_red_lgC PF02867.15 EWM22110.1 - 0.00069 18.3 0.0 0.29 9.6 0.0 3.0 3 0 0 3 3 3 3 Ribonucleotide reductase, barrel domain HORMA PF02301.18 EWM22111.1 - 4.7e-44 150.5 0.0 1.6e-43 148.8 0.0 1.9 1 1 0 1 1 1 1 HORMA domain GntR PF00392.21 EWM22111.1 - 0.022 14.4 0.1 0.096 12.3 0.1 2.1 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family UFD1 PF03152.14 EWM22112.1 - 4.2e-28 98.0 0.0 3.2e-21 75.6 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 UBX PF00789.20 EWM22112.1 - 1.8e-09 37.7 0.0 3.4e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 UBX domain CDC48_2 PF02933.17 EWM22112.1 - 0.0011 18.7 0.0 0.023 14.5 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 DUF905 PF06006.12 EWM22112.1 - 0.015 15.3 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF905) Xpo1 PF08389.12 EWM22115.1 - 8.2e-11 42.2 0.0 2.5e-10 40.6 0.0 1.9 1 0 0 1 1 1 1 Exportin 1-like protein IBN_N PF03810.19 EWM22115.1 - 1.5e-05 24.9 0.2 0.00024 20.9 0.0 2.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain THOC7 PF05615.13 EWM22117.1 - 8.6e-16 58.4 1.9 8.6e-16 58.4 1.9 2.2 1 1 1 2 2 2 1 Tho complex subunit 7 BMFP PF04380.13 EWM22117.1 - 0.19 12.2 7.6 3.4 8.2 1.4 2.9 2 0 0 2 2 2 0 Membrane fusogenic activity DUF1843 PF08898.10 EWM22117.1 - 0.34 11.4 0.3 0.34 11.4 0.3 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF1843) APG6_N PF17675.1 EWM22117.1 - 7.8 7.0 15.0 0.34 11.4 6.9 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region Cse1 PF08506.10 EWM22119.1 - 7.5e-128 426.4 0.1 2.4e-127 424.8 0.0 1.8 2 0 0 2 2 2 1 Cse1 CAS_CSE1 PF03378.15 EWM22119.1 - 7.4e-98 327.9 0.0 1.4e-97 327.0 0.0 1.4 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 EWM22119.1 - 3.4e-09 36.5 0.0 1e-08 34.9 0.0 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EWM22119.1 - 0.00031 20.8 0.2 0.0065 16.5 0.0 3.2 3 0 0 3 3 3 1 Exportin 1-like protein HEAT_EZ PF13513.6 EWM22119.1 - 0.0099 16.4 0.8 0.42 11.2 0.1 4.1 4 0 0 4 4 4 1 HEAT-like repeat HEAT PF02985.22 EWM22119.1 - 0.052 13.8 3.5 0.66 10.4 0.1 3.8 4 0 0 4 4 4 0 HEAT repeat Arf PF00025.21 EWM22120.1 - 1.1e-68 230.1 0.0 1.3e-68 229.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EWM22120.1 - 1.9e-12 47.5 0.0 2.6e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EWM22120.1 - 5.2e-12 45.7 0.0 6.2e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EWM22120.1 - 4e-11 42.7 0.9 3.7e-05 23.1 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EWM22120.1 - 1.8e-08 34.0 0.0 2.3e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EWM22120.1 - 3e-07 30.1 0.0 3.9e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EWM22120.1 - 6.4e-06 26.2 0.0 9e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EWM22120.1 - 0.00055 19.5 0.0 0.004 16.7 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain TniB PF05621.11 EWM22120.1 - 0.0069 15.8 0.1 0.01 15.3 0.1 1.2 1 0 0 1 1 1 1 Bacterial TniB protein eIF-1a PF01176.19 EWM22121.1 - 2.8e-10 39.8 0.0 4.8e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Methyltransf_25 PF13649.6 EWM22122.1 - 1.1e-08 35.6 0.0 2.8e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EWM22122.1 - 2e-08 34.0 0.0 2.9e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EWM22122.1 - 3.4e-06 27.6 0.0 9.6e-06 26.2 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 EWM22122.1 - 7.3e-06 25.6 0.0 1.7e-05 24.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_9 PF08003.11 EWM22122.1 - 4.9e-05 22.4 0.0 7e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 EWM22122.1 - 0.00014 21.2 0.1 0.0002 20.8 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 EWM22122.1 - 0.00078 19.3 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EWM22122.1 - 0.00092 19.1 0.0 0.0017 18.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EWM22122.1 - 0.003 17.5 0.0 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 EWM22122.1 - 0.0036 17.2 0.0 0.0056 16.5 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Cons_hypoth95 PF03602.15 EWM22122.1 - 0.019 14.6 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 GidB PF02527.15 EWM22122.1 - 0.024 14.0 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G RrnaAD PF00398.20 EWM22122.1 - 0.025 13.6 0.0 0.036 13.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PRMT5_C PF17286.2 EWM22122.1 - 0.077 12.9 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 PRMT5 oligomerisation domain Methyltransf_24 PF13578.6 EWM22122.1 - 0.079 14.0 0.0 0.19 12.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 EWM22122.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Cystatin PF00031.21 EWM22123.1 - 2.8e-08 33.9 0.0 3.7e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Cystatin domain SQAPI PF16845.5 EWM22123.1 - 0.07 13.5 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Aspartic acid proteinase inhibitor Aldedh PF00171.22 EWM22125.1 - 2.1e-133 445.2 0.0 2.6e-133 444.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FlgN PF05130.12 EWM22125.1 - 0.22 12.0 0.1 0.37 11.3 0.1 1.2 1 0 0 1 1 1 0 FlgN protein Fer4_13 PF13370.6 EWM22126.1 - 3e-08 34.1 0.5 6.9e-08 32.9 0.5 1.6 1 1 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Lactamase_B PF00753.27 EWM22126.1 - 1.2e-07 31.9 0.4 2.3e-07 31.0 0.4 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Fer4_15 PF13459.6 EWM22126.1 - 2.9e-05 24.7 0.5 7.5e-05 23.4 0.5 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Lactamase_B_5 PF14597.6 EWM22126.1 - 0.057 12.9 0.0 0.77 9.2 0.0 2.2 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Metallophos_2 PF12850.7 EWM22127.1 - 2.4e-05 24.6 0.0 0.11 12.7 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EWM22127.1 - 6.7e-05 23.5 0.0 0.0058 17.1 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase EMP70 PF02990.16 EWM22128.1 - 9.8e-154 512.8 16.8 9.8e-154 512.8 16.8 1.3 2 0 0 2 2 2 1 Endomembrane protein 70 CorA PF01544.18 EWM22128.1 - 0.029 13.7 0.4 0.029 13.7 0.4 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein NapE PF06796.11 EWM22128.1 - 0.14 11.7 0.2 0.14 11.7 0.2 2.2 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE DUF1129 PF06570.11 EWM22128.1 - 9.6 5.6 17.2 0.042 13.3 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Pkinase PF00069.25 EWM22129.1 - 8.6e-13 48.3 0.0 5.7e-12 45.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EWM22129.1 - 7.4e-05 21.7 0.0 0.0001 21.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Yop-YscD_cpl PF16697.5 EWM22129.1 - 0.00015 22.0 0.1 0.00036 20.8 0.1 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain PIP49_C PF12260.8 EWM22129.1 - 0.021 14.5 0.0 1.8 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 zf-Tim10_DDP PF02953.15 EWM22130.1 - 1.8e-18 65.9 2.8 1.8e-18 65.9 2.8 1.8 1 1 1 2 2 2 1 Tim10/DDP family zinc finger MHB PF16525.5 EWM22130.1 - 0.0071 16.6 0.1 0.034 14.4 0.0 1.8 2 0 0 2 2 2 1 Haemophore, haem-binding Glycos_transf_2 PF00535.26 EWM22131.1 - 1.3e-26 93.4 0.0 1.8e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EWM22131.1 - 4.5e-12 46.3 0.1 6.7e-12 45.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 EWM22131.1 - 0.013 16.0 0.0 0.034 14.6 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 EWM22131.1 - 0.041 13.4 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 GCP_C_terminal PF04130.13 EWM22132.1 - 2.4e-73 247.3 0.0 3.2e-73 246.9 0.0 1.1 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EWM22132.1 - 5.7e-42 144.4 0.0 8.7e-42 143.8 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal ETC_C1_NDUFA4 PF04800.12 EWM22133.1 - 5.7e-26 90.6 1.7 8.4e-26 90.1 1.7 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region VIR_N PF15912.5 EWM22133.1 - 0.16 11.5 3.3 0.23 11.0 3.3 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal DEAD PF00270.29 EWM22134.1 - 4.1e-45 153.7 0.0 5.9e-45 153.2 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EWM22134.1 - 2.3e-22 79.5 0.0 1.7e-21 76.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EWM22134.1 - 1.9e-15 56.8 0.1 3.8e-15 55.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EWM22134.1 - 7.8e-06 26.0 0.0 1.2e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EWM22134.1 - 0.14 11.3 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase RNA_POL_M_15KD PF02150.16 EWM22135.1 - 4.6e-06 26.4 5.7 1.3e-05 24.9 2.6 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 EWM22135.1 - 7.2e-05 22.6 0.7 7.2e-05 22.6 0.7 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) zf-ribbon_3 PF13248.6 EWM22135.1 - 1.2 8.7 8.5 2.2 7.8 0.2 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Ogr_Delta PF04606.12 EWM22135.1 - 1.5 8.9 13.0 0.1 12.6 2.2 3.1 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger Snf7 PF03357.21 EWM22136.1 - 2.4e-28 98.9 13.2 2.4e-28 98.9 13.2 1.5 1 1 0 1 1 1 1 Snf7 Sporozoite_P67 PF05642.11 EWM22136.1 - 0.017 13.3 1.7 0.023 12.8 1.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen THF_DHG_CYH PF00763.23 EWM22137.1 - 4.8e-22 78.4 0.0 7.8e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 EWM22137.1 - 4.4e-14 52.1 0.1 1.5e-12 47.2 0.2 2.9 2 1 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.19 EWM22137.1 - 0.0027 17.1 0.0 0.0098 15.3 0.0 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.15 EWM22137.1 - 0.1 11.5 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family DUF3796 PF12676.7 EWM22137.1 - 0.17 12.3 0.1 0.27 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) LRR_6 PF13516.6 EWM22138.1 - 1.3e-37 124.6 14.5 0.00011 22.0 0.0 11.2 11 0 0 11 11 11 9 Leucine Rich repeat LRR_4 PF12799.7 EWM22138.1 - 1.7e-11 44.2 4.7 0.61 10.6 0.0 7.2 5 3 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EWM22138.1 - 1.7e-08 33.8 2.8 37 5.4 0.1 8.9 8 1 0 8 8 8 0 Leucine Rich Repeat LRR_8 PF13855.6 EWM22138.1 - 0.00037 20.2 15.7 17 5.3 0.1 8.6 9 2 0 9 9 9 3 Leucine rich repeat zf_C2H2_ZHX PF18387.1 EWM22138.1 - 0.043 13.5 0.1 0.085 12.5 0.1 1.4 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain PT PF04886.12 EWM22139.1 - 8.9e-13 47.5 83.8 8.4e-06 25.2 17.1 5.6 3 1 0 3 3 3 3 PT repeat Cyt-b5 PF00173.28 EWM22140.1 - 0.031 14.4 0.0 0.062 13.5 0.0 1.5 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain Na_Ca_ex PF01699.24 EWM22142.1 - 5.8e-41 139.9 36.2 6.7e-21 74.8 15.3 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Exo_endo_phos PF03372.23 EWM22143.1 - 1.8e-05 24.4 0.0 3.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Rnf-Nqr PF02508.14 EWM22143.1 - 0.065 13.2 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Rnf-Nqr subunit, membrane protein DXP_synthase_N PF13292.6 EWM22144.1 - 1.2e-106 355.9 0.0 2.7e-106 354.8 0.0 1.6 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.24 EWM22144.1 - 3.5e-40 137.6 0.0 6.4e-40 136.7 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EWM22144.1 - 5.2e-23 81.3 0.0 1.2e-22 80.1 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.21 EWM22144.1 - 1.4e-05 24.9 0.1 4.1e-05 23.4 0.1 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.21 EWM22144.1 - 0.00014 20.9 0.1 0.25 10.2 0.3 2.9 2 1 0 2 2 2 2 Transketolase, thiamine diphosphate binding domain E1_dh PF00676.20 EWM22144.1 - 0.082 11.8 0.1 0.14 11.1 0.1 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component ER_lumen_recept PF00810.18 EWM22145.1 - 9.3e-52 175.8 7.6 9.3e-52 175.8 7.6 1.5 2 0 0 2 2 2 1 ER lumen protein retaining receptor Cyd_oper_YbgE PF09600.10 EWM22145.1 - 0.091 13.1 4.2 0.096 13.1 1.6 2.4 2 1 0 2 2 2 0 Cyd operon protein YbgE (Cyd_oper_YbgE) IPK PF03770.16 EWM22146.1 - 1.1e-30 107.0 0.0 1.5e-17 64.1 0.0 2.1 2 0 0 2 2 2 2 Inositol polyphosphate kinase WD40 PF00400.32 EWM22147.1 - 7.6e-12 45.6 5.4 0.013 16.3 0.0 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat RWP-RK PF02042.15 EWM22148.1 - 1.7e-20 72.7 0.2 3.6e-20 71.7 0.2 1.6 1 0 0 1 1 1 1 RWP-RK domain PspA_IM30 PF04012.12 EWM22149.1 - 9.3e-54 182.3 23.1 1.2e-53 181.9 23.1 1.2 1 0 0 1 1 1 1 PspA/IM30 family LAGLIDADG_WhiA PF14527.6 EWM22149.1 - 0.023 14.8 0.6 0.06 13.4 0.6 1.8 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain Spc7 PF08317.11 EWM22149.1 - 0.074 11.9 22.5 0.045 12.6 12.2 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Prefoldin_2 PF01920.20 EWM22149.1 - 0.42 10.6 16.6 0.63 10.0 1.7 3.6 1 1 0 2 2 2 0 Prefoldin subunit LMBR1 PF04791.16 EWM22149.1 - 0.99 8.2 2.4 1.2 7.9 2.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Occludin_ELL PF07303.13 EWM22149.1 - 1 10.1 7.6 6.9 7.5 0.5 2.5 2 0 0 2 2 2 0 Occludin homology domain DUF4665 PF15679.5 EWM22149.1 - 1.1 9.9 7.9 0.26 11.9 0.7 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4665) DUF4315 PF14193.6 EWM22149.1 - 1.3 9.0 11.0 0.1 12.6 2.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4315) Fib_alpha PF08702.10 EWM22149.1 - 1.6 8.9 13.7 2.2 8.5 2.4 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF2937 PF11157.8 EWM22149.1 - 1.6 8.4 8.2 0.58 9.9 1.9 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF2937) DUF484 PF04340.12 EWM22149.1 - 3.1 7.4 11.4 0.31 10.7 5.2 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF484 NPV_P10 PF05531.12 EWM22149.1 - 5.4 7.5 7.1 9.8 6.7 1.0 3.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 EWM22149.1 - 7.7 7.2 14.5 0.36 11.5 0.7 3.5 2 2 1 3 3 3 0 SlyX Aminotran_5 PF00266.19 EWM22150.1 - 3.5e-27 95.3 0.0 6.1e-13 48.5 0.0 3.1 3 0 0 3 3 3 2 Aminotransferase class-V Globin PF00042.22 EWM22150.1 - 8.1e-10 39.2 0.0 1.5e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 Globin Aminotran_1_2 PF00155.21 EWM22150.1 - 0.008 15.4 0.0 0.019 14.2 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II Ctr PF04145.15 EWM22150.1 - 2.8 8.5 3.9 39 4.8 0.2 2.8 2 0 0 2 2 2 0 Ctr copper transporter family ApbA PF02558.16 EWM22153.1 - 5e-25 87.9 0.0 5.3e-13 48.9 0.0 2.2 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 EWM22153.1 - 3.7e-18 65.9 0.0 7.2e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Cyclin_N PF00134.23 EWM22155.1 - 0.42 10.4 0.0 0.42 10.4 0.0 2.8 3 0 0 3 3 3 0 Cyclin, N-terminal domain Cyclin_C PF02984.19 EWM22155.1 - 1.6 8.9 0.0 1.6 8.9 0.0 3.0 3 0 0 3 3 3 0 Cyclin, C-terminal domain ATP_bind_1 PF03029.17 EWM22156.1 - 4.3e-75 252.6 0.0 2.1e-68 230.7 0.0 2.0 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein CbiA PF01656.23 EWM22156.1 - 0.00017 21.6 0.0 0.00029 20.9 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 EWM22156.1 - 0.00042 19.4 0.0 0.00071 18.6 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EWM22156.1 - 0.00086 19.1 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EWM22156.1 - 0.0059 17.0 0.0 0.01 16.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) GRP PF07172.11 EWM22156.1 - 0.011 16.5 0.3 0.018 15.7 0.3 1.4 1 0 0 1 1 1 0 Glycine rich protein family AAA_33 PF13671.6 EWM22156.1 - 0.015 15.5 0.0 0.037 14.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EWM22156.1 - 0.024 15.2 0.0 0.12 13.0 0.0 2.2 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EWM22156.1 - 0.036 14.0 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 NTPase CLP1_P PF16575.5 EWM22156.1 - 0.037 13.8 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_31 PF13614.6 EWM22156.1 - 0.04 13.8 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 EWM22156.1 - 0.041 13.5 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 EWM22156.1 - 0.051 13.1 0.0 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EWM22156.1 - 0.055 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EWM22156.1 - 0.094 13.1 0.1 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.15 EWM22156.1 - 0.13 11.4 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase MMR_HSR1 PF01926.23 EWM22156.1 - 0.14 12.3 0.0 1.3 9.1 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 EWM22157.1 - 1.4e-47 162.5 0.0 9.3e-41 140.2 0.0 2.1 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein GRP PF07172.11 EWM22157.1 - 0.0074 17.0 0.3 0.012 16.3 0.3 1.4 1 0 0 1 1 1 1 Glycine rich protein family Tom22 PF04281.13 EWM22158.1 - 2.5e-06 27.3 0.3 3.3e-06 26.9 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DUF4870 PF09685.10 EWM22158.1 - 0.12 12.5 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4870) HATPase_c PF02518.26 EWM22159.1 - 1.9e-11 44.5 0.0 3.3e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BCDHK_Adom3 PF10436.9 EWM22159.1 - 3.4e-07 30.2 0.0 9.4e-07 28.8 0.0 1.7 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c_3 PF13589.6 EWM22159.1 - 0.0015 18.4 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4505 PF14956.6 EWM22160.1 - 1.3e-29 103.2 0.0 1.9e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4505) PGK PF00162.19 EWM22161.1 - 1.2e-132 442.5 0.3 1.4e-132 442.2 0.3 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase IF2_N PF04760.15 EWM22161.1 - 0.037 13.9 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Nucleoplasmin PF03066.15 EWM22162.1 - 0.032 14.7 0.3 0.072 13.6 0.3 1.5 1 0 0 1 1 1 0 Nucleoplasmin/nucleophosmin domain Rsd_AlgQ PF04353.13 EWM22162.1 - 0.32 10.9 0.0 0.32 10.9 0.0 2.6 3 0 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ TMF_DNA_bd PF12329.8 EWM22162.1 - 4.5 7.4 18.8 0.74 9.8 1.5 4.0 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Tropomyosin PF00261.20 EWM22162.1 - 5.5 6.3 27.5 0.15 11.4 2.3 3.8 4 0 0 4 4 4 0 Tropomyosin CCDC-167 PF15188.6 EWM22162.1 - 7.1 7.0 9.1 8.1 6.9 0.3 3.2 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 GAS PF13851.6 EWM22162.1 - 8.1 5.7 26.8 0.39 10.1 1.2 3.5 4 0 0 4 4 4 0 Growth-arrest specific micro-tubule binding Abhydrolase_1 PF00561.20 EWM22164.1 - 2.7e-15 56.7 0.0 4e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 EWM22164.1 - 1.8e-09 37.0 0.1 1.3e-08 34.3 0.0 2.4 2 1 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Peripla_BP_6 PF13458.6 EWM22164.1 - 0.0073 16.0 1.8 0.036 13.7 0.0 2.1 2 0 0 2 2 2 1 Periplasmic binding protein Hydrolase_4 PF12146.8 EWM22164.1 - 0.027 13.8 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Papilloma_E5A PF05776.12 EWM22164.1 - 0.075 13.4 3.3 0.14 12.5 3.3 1.4 1 0 0 1 1 1 0 Papillomavirus E5A protein BP28CT PF08146.12 EWM22165.1 - 3.3e-31 108.3 0.0 6.3e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 BP28CT (NUC211) domain HEAT_2 PF13646.6 EWM22165.1 - 0.1 13.0 0.1 0.24 11.8 0.1 1.6 1 0 0 1 1 1 0 HEAT repeats PRP3 PF08572.10 EWM22165.1 - 1.7 8.3 4.3 2.7 7.7 4.3 1.2 1 0 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) Acyl_transf_3 PF01757.22 EWM22166.1 - 1.6e-10 40.6 33.5 1.6e-10 40.6 33.5 2.5 3 0 0 3 3 3 1 Acyltransferase family Chloroa_b-bind PF00504.21 EWM22167.1 - 3.6e-38 131.6 0.1 4.9e-38 131.2 0.1 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DUF2905 PF11146.8 EWM22167.1 - 0.0017 18.5 0.4 12 6.2 0.0 3.6 3 0 0 3 3 3 3 Protein of unknown function (DUF2905) PPR PF01535.20 EWM22169.1 - 1e-09 37.9 0.4 0.0041 17.3 0.1 5.1 6 0 0 6 6 6 2 PPR repeat PPR_2 PF13041.6 EWM22169.1 - 5.4e-06 26.5 0.0 0.00027 21.1 0.0 3.3 4 0 0 4 4 4 1 PPR repeat family PPR_1 PF12854.7 EWM22169.1 - 0.049 13.3 0.0 1.7 8.5 0.1 2.6 3 0 0 3 3 3 0 PPR repeat PPR_long PF17177.4 EWM22169.1 - 0.082 12.3 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP TPR_2 PF07719.17 EWM22169.1 - 0.13 12.5 2.0 29 5.1 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_3 PF13812.6 EWM22169.1 - 0.13 12.3 0.0 4.9 7.3 0.0 2.6 3 0 0 3 3 3 0 Pentatricopeptide repeat domain CDH PF02611.15 EWM22170.1 - 5.7e-06 26.1 0.1 2.3e-05 24.1 0.1 1.8 1 1 0 1 1 1 1 CDP-diacylglycerol pyrophosphatase ABC2_membrane PF01061.24 EWM22171.1 - 1.3e-76 256.7 54.3 7.2e-43 146.5 22.8 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EWM22171.1 - 6.2e-39 133.6 0.0 3.7e-21 76.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EWM22171.1 - 6.6e-08 32.7 0.1 0.28 11.0 0.0 3.3 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EWM22171.1 - 1.3e-07 31.4 0.3 0.0094 15.5 0.1 2.4 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EWM22171.1 - 1.8e-07 31.2 0.3 0.0099 15.8 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EWM22171.1 - 2.6e-07 31.2 0.5 0.0024 18.3 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EWM22171.1 - 1.7e-06 27.7 2.6 0.029 14.1 0.6 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_33 PF13671.6 EWM22171.1 - 5.5e-05 23.4 0.1 0.19 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EWM22171.1 - 0.00015 22.1 0.1 0.52 10.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 EWM22171.1 - 0.00018 22.1 0.1 0.89 10.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EWM22171.1 - 0.00041 20.9 0.1 0.31 11.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EWM22171.1 - 0.0005 20.4 0.4 0.84 9.9 0.1 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 EWM22171.1 - 0.00077 19.4 0.4 0.57 10.1 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA PF00004.29 EWM22171.1 - 0.00091 19.7 0.8 0.051 14.0 0.0 2.7 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EWM22171.1 - 0.001 18.8 0.5 0.56 9.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain cobW PF02492.19 EWM22171.1 - 0.0011 18.6 0.4 0.98 9.0 0.1 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 EWM22171.1 - 0.0015 18.6 1.3 0.46 10.6 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase SMC_N PF02463.19 EWM22171.1 - 0.0023 17.4 0.0 0.19 11.1 0.0 3.0 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain RNA_helicase PF00910.22 EWM22171.1 - 0.02 15.3 0.0 1.5 9.3 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.14 EWM22171.1 - 0.023 14.7 1.4 0.2 11.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 EWM22171.1 - 0.028 13.7 0.3 5.5 6.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Ribosomal_L30 PF00327.20 EWM22171.1 - 0.042 13.7 0.2 0.5 10.3 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein L30p/L7e AAA_19 PF13245.6 EWM22171.1 - 0.069 13.5 0.5 2.8 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EWM22171.1 - 0.084 12.6 1.6 5.7 6.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EWM22171.1 - 0.1 12.7 0.6 5.6 7.0 0.1 2.3 2 0 0 2 2 2 0 Dynamin family PDR_CDR PF06422.12 EWM22171.1 - 0.17 11.8 12.7 0.23 11.4 0.0 3.5 4 0 0 4 4 3 0 CDR ABC transporter Rad17 PF03215.15 EWM22171.1 - 0.17 11.8 0.0 5.5 6.9 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_15 PF13175.6 EWM22171.1 - 0.25 11.0 0.1 3.3 7.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain TsaE PF02367.17 EWM22171.1 - 0.3 11.1 2.7 20 5.2 0.3 3.0 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Carb_anhydrase PF00194.21 EWM22174.1 - 2.6e-29 102.5 0.1 3.9e-29 101.9 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Tmemb_14 PF03647.13 EWM22176.1 - 9.2e-06 26.3 8.1 1.2e-05 25.9 8.1 1.2 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF3278 PF11683.8 EWM22176.1 - 0.44 10.6 2.4 0.59 10.2 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) EI24 PF07264.11 EWM22176.1 - 2.6 8.3 12.4 5 7.3 12.4 1.5 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) SBBP PF06739.11 EWM22178.1 - 7.3e-09 35.5 11.6 0.023 14.7 0.0 5.4 5 0 0 5 5 5 4 Beta-propeller repeat WBS_methylT PF12589.8 EWM22178.1 - 0.043 14.6 1.5 0.11 13.3 1.5 1.6 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome DUF1491 PF07372.12 EWM22178.1 - 0.066 13.6 0.0 0.53 10.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1491) Smr PF01713.21 EWM22179.1 - 0.053 13.9 0.0 0.17 12.3 0.0 1.7 2 0 0 2 2 2 0 Smr domain Prefoldin PF02996.17 EWM22180.1 - 1.5e-25 89.5 1.5 2e-25 89.0 1.5 1.2 1 0 0 1 1 1 1 Prefoldin subunit Poxvirus_B22R_C PF13168.6 EWM22180.1 - 0.0084 15.6 0.0 0.0099 15.4 0.0 1.2 1 0 0 1 1 1 1 Poxvirus B22R protein C-terminal F_actin_cap_B PF01115.17 EWM22180.1 - 0.018 14.7 0.2 0.027 14.1 0.2 1.2 1 0 0 1 1 1 0 F-actin capping protein, beta subunit Prefoldin_2 PF01920.20 EWM22180.1 - 0.024 14.6 0.2 0.12 12.3 0.1 2.0 2 0 0 2 2 2 0 Prefoldin subunit Vac_Fusion PF02346.16 EWM22180.1 - 0.053 13.1 0.6 3.6 7.3 0.6 2.3 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 FlaC_arch PF05377.11 EWM22180.1 - 0.32 11.4 2.9 2.1 8.8 0.3 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) PT PF04886.12 EWM22181.1 - 0.0009 18.7 13.1 0.0009 18.7 13.1 3.9 2 1 1 3 3 3 1 PT repeat SBBP PF06739.11 EWM22181.1 - 0.0036 17.3 14.0 0.0069 16.4 0.3 4.2 4 0 0 4 4 4 2 Beta-propeller repeat PQQ PF01011.21 EWM22181.1 - 0.0038 17.1 0.0 3.1 7.9 0.0 3.1 2 0 0 2 2 2 2 PQQ enzyme repeat PQQ_3 PF13570.6 EWM22181.1 - 0.046 14.2 0.1 0.046 14.2 0.1 4.0 3 0 0 3 3 3 0 PQQ-like domain Complex1_51K PF01512.17 EWM22182.1 - 1.3e-06 28.4 0.4 1.7e-06 27.9 0.4 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit PPR_2 PF13041.6 EWM22183.1 - 5.7e-62 205.7 0.9 1.4e-09 37.9 0.0 11.1 4 2 7 11 11 11 10 PPR repeat family PPR PF01535.20 EWM22183.1 - 5.8e-55 179.8 4.7 3.4e-05 23.8 0.0 13.4 13 0 0 13 13 13 11 PPR repeat PPR_3 PF13812.6 EWM22183.1 - 1.7e-47 159.3 0.0 2.3e-09 37.2 0.0 6.4 6 0 0 6 6 6 6 Pentatricopeptide repeat domain PPR_long PF17177.4 EWM22183.1 - 9.5e-29 100.3 0.1 1.8e-12 47.1 0.0 4.7 2 1 1 4 4 4 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EWM22183.1 - 6.7e-25 86.5 2.8 0.00013 21.6 0.0 11.6 12 1 0 12 12 12 5 PPR repeat MRP-S27 PF10037.9 EWM22183.1 - 0.052 12.4 0.0 1.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 PPR_2 PF13041.6 EWM22184.1 - 2.7e-34 117.1 0.0 5.4e-06 26.5 0.0 10.9 6 3 6 12 12 12 8 PPR repeat family PPR PF01535.20 EWM22184.1 - 2e-30 102.9 5.2 0.033 14.4 0.0 13.6 14 0 0 14 14 14 6 PPR repeat PPR_3 PF13812.6 EWM22184.1 - 1.1e-23 83.1 0.0 2e-05 24.6 0.0 7.0 4 2 2 7 7 7 5 Pentatricopeptide repeat domain PPR_long PF17177.4 EWM22184.1 - 9.9e-19 67.5 0.0 2.6e-05 23.7 0.0 5.3 4 2 1 5 5 5 4 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EWM22184.1 - 1.1e-08 34.6 1.3 0.04 13.6 0.0 6.0 7 0 0 7 7 7 2 PPR repeat COX5A PF02284.16 EWM22184.1 - 0.0059 16.6 0.1 4.1 7.5 0.0 4.3 4 1 1 5 5 5 1 Cytochrome c oxidase subunit Va Exog_C PF18026.1 EWM22184.1 - 0.015 15.3 0.0 13 5.9 0.0 3.3 3 0 0 3 3 3 0 Endo/exonuclease (EXOG) C-terminal domain TPR_15 PF13429.6 EWM22184.1 - 0.019 14.2 0.1 34 3.5 0.0 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EWM22184.1 - 0.073 12.7 3.7 7.4 6.2 0.1 3.6 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) Pex19 PF04614.12 EWM22184.1 - 0.19 11.4 0.1 3.1 7.5 0.1 2.9 3 1 0 3 3 3 0 Pex19 protein family MRP-S27 PF10037.9 EWM22184.1 - 0.26 10.1 0.0 30 3.3 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial 28S ribosomal protein S27 TPR_14 PF13428.6 EWM22184.1 - 0.44 11.5 21.1 12 7.1 0.1 8.9 8 2 3 11 11 11 0 Tetratricopeptide repeat MTCP1 PF08991.10 EWM22187.1 - 0.19 12.0 0.1 0.29 11.4 0.1 1.2 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type Ribosomal_L13e PF01294.18 EWM22191.1 - 2e-75 252.6 4.6 2.3e-75 252.4 4.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L13e GTPase_binding PF09027.10 EWM22192.1 - 0.11 12.5 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 GTPase binding Mito_carr PF00153.27 EWM22193.1 - 3.6e-16 58.9 3.9 4.2e-05 23.4 0.2 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein SAICAR_synt PF01259.18 EWM22195.1 - 3.5e-26 92.4 0.0 4.5e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase Beta_propel PF09826.9 EWM22195.1 - 0.16 10.8 0.0 0.18 10.6 0.0 1.0 1 0 0 1 1 1 0 Beta propeller domain Transferase PF02458.15 EWM22196.1 - 2.2e-06 26.6 0.0 2.4e-06 26.5 0.0 1.0 1 0 0 1 1 1 1 Transferase family Exo_endo_phos PF03372.23 EWM22199.1 - 0.0027 17.3 0.0 0.0043 16.6 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Methyltranf_PUA PF13636.6 EWM22199.1 - 0.29 11.2 0.8 2.6 8.1 0.8 2.2 1 1 0 1 1 1 0 RNA-binding PUA-like domain of methyltransferase RsmF Exo_endo_phos PF03372.23 EWM22200.1 - 0.0023 17.5 0.0 0.0032 17.0 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Methyltranf_PUA PF13636.6 EWM22200.1 - 0.22 11.5 0.8 2.2 8.3 0.8 2.2 1 1 0 1 1 1 0 RNA-binding PUA-like domain of methyltransferase RsmF MA3 PF02847.17 EWM22202.1 - 2.3e-13 50.1 0.0 2.7e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 MA3 domain NAD_Gly3P_dh_C PF07479.14 EWM22203.1 - 1.6e-26 93.3 0.0 1.8e-26 93.1 0.0 1.0 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus DUF3316 PF11777.8 EWM22205.1 - 0.038 14.1 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3316) NOA36 PF06524.12 EWM22206.1 - 1.9 7.8 4.7 2.9 7.1 4.7 1.2 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 EWM22206.1 - 2.7 8.4 7.5 4.4 7.8 7.5 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GP67 PF17634.2 EWM22206.1 - 5.2 7.6 12.0 0.83 10.1 8.1 1.6 2 0 0 2 2 2 0 Gene product 67 ABC_tran PF00005.27 EWM22207.1 - 1.6e-24 87.0 0.0 2.5e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EWM22207.1 - 1.9e-06 27.9 0.0 0.023 14.5 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EWM22207.1 - 8.2e-05 23.0 0.0 0.00012 22.5 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 EWM22207.1 - 0.00012 21.6 0.1 0.0049 16.3 0.1 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EWM22207.1 - 0.00012 22.1 0.9 0.00017 21.6 0.3 1.5 2 0 0 2 2 1 1 RsgA GTPase AAA_29 PF13555.6 EWM22207.1 - 0.00015 21.4 0.1 0.00035 20.2 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 EWM22207.1 - 0.0002 21.0 0.2 0.00046 19.8 0.2 1.6 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EWM22207.1 - 0.00056 20.5 0.1 0.001 19.6 0.1 1.3 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EWM22207.1 - 0.00066 19.7 0.1 0.0016 18.5 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EWM22207.1 - 0.0042 17.1 0.1 0.0073 16.4 0.1 1.3 1 0 0 1 1 1 1 Dynamin family AAA_22 PF13401.6 EWM22207.1 - 0.035 14.4 0.1 0.06 13.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 EWM22207.1 - 0.081 12.5 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 EWM22207.1 - 0.1 13.1 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EWM22207.1 - 0.1 11.6 1.6 0.092 11.8 0.3 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_ATPase PF09818.9 EWM22207.1 - 0.13 11.1 0.2 0.27 10.0 0.2 1.4 1 0 0 1 1 1 0 Predicted ATPase of the ABC class DLIC PF05783.11 EWM22207.1 - 0.14 11.0 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Cytidylate_kin PF02224.18 EWM22207.1 - 0.18 11.5 0.2 0.34 10.6 0.2 1.4 1 0 0 1 1 1 0 Cytidylate kinase NACHT PF05729.12 EWM22207.1 - 0.19 11.7 0.1 0.79 9.6 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 EWM22207.1 - 0.21 11.8 0.2 0.35 11.1 0.2 1.3 1 0 0 1 1 1 0 AAA domain Adeno_IVa2 PF02456.15 EWM22207.1 - 0.23 10.2 0.1 0.35 9.6 0.1 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_10 PF12846.7 EWM22207.1 - 0.24 10.3 0.1 0.89 8.4 0.1 1.7 2 0 0 2 2 2 0 AAA-like domain Glyoxalase PF00903.25 EWM22209.1 - 8.5e-06 26.0 0.0 0.055 13.7 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EWM22209.1 - 2.5e-05 24.5 0.0 0.042 14.1 0.0 2.5 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 EWM22209.1 - 9.7e-05 22.6 0.1 0.00055 20.1 0.1 2.3 3 0 0 3 3 3 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 EWM22209.1 - 0.15 12.1 0.2 8.7 6.4 0.2 3.1 3 1 0 3 3 3 0 Glyoxalase-like domain Glyoxalase PF00903.25 EWM22210.1 - 7.4e-06 26.2 0.0 0.051 13.8 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EWM22210.1 - 2.2e-05 24.7 0.0 0.039 14.2 0.0 2.5 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 EWM22210.1 - 8.8e-05 22.7 0.1 0.00052 20.2 0.1 2.3 3 0 0 3 3 3 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 EWM22210.1 - 0.13 12.3 0.2 8.1 6.5 0.2 3.1 3 1 0 3 3 3 0 Glyoxalase-like domain PAE PF03283.13 EWM22212.1 - 1.8e-50 172.1 0.0 2.3e-50 171.7 0.0 1.0 1 0 0 1 1 1 1 Pectinacetylesterase PAP1 PF08601.10 EWM22213.1 - 2.5 7.7 19.5 4 7.1 19.5 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 GREB1 PF15782.5 EWM22213.1 - 5.5 4.0 17.3 6.6 3.7 17.3 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PAP1 PF08601.10 EWM22214.1 - 0.54 9.9 17.4 0.85 9.3 17.4 1.4 1 0 0 1 1 1 0 Transcription factor PAP1 GREB1 PF15782.5 EWM22214.1 - 6.5 3.7 17.5 7.8 3.5 17.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Nt_Gln_amidase PF09764.9 EWM22215.1 - 7.3e-41 139.8 0.0 3.9e-28 98.3 0.0 2.1 2 0 0 2 2 2 2 N-terminal glutamine amidase C1_2 PF03107.16 EWM22216.1 - 0.0086 16.4 3.8 0.016 15.5 3.8 1.5 1 0 0 1 1 1 1 C1 domain ZZ PF00569.17 EWM22216.1 - 0.29 11.0 7.6 0.5 10.2 7.6 1.3 1 0 0 1 1 1 0 Zinc finger, ZZ type BACK PF07707.15 EWM22218.1 - 0.019 15.1 0.0 0.14 12.3 0.0 2.1 1 1 0 1 1 1 0 BTB And C-terminal Kelch Ustilago_mating PF05722.12 EWM22220.1 - 0.0047 16.5 0.0 0.0067 16.0 0.0 1.2 1 0 0 1 1 1 1 Ustilago B locus mating-type protein PAE PF03283.13 EWM22220.1 - 0.13 11.4 0.5 0.99 8.5 0.1 1.9 2 0 0 2 2 2 0 Pectinacetylesterase NT-C2 PF10358.9 EWM22222.1 - 6.4e-05 22.7 0.0 9.6e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins SBF PF01758.16 EWM22224.1 - 9.2e-51 172.3 13.7 1.6e-50 171.5 13.7 1.4 1 0 0 1 1 1 1 Sodium Bile acid symporter family CDC45 PF02724.14 EWM22225.1 - 0.00035 19.0 6.0 0.00041 18.8 6.0 1.0 1 0 0 1 1 1 1 CDC45-like protein BTB PF00651.31 EWM22225.1 - 0.014 15.6 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain PTPRCAP PF15713.5 EWM22225.1 - 0.023 15.0 11.1 0.032 14.5 11.1 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated RPA43_OB PF17875.1 EWM22225.1 - 0.04 14.5 2.5 0.052 14.2 2.5 1.2 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Usp PF00582.26 EWM22225.1 - 0.062 13.8 1.7 0.11 13.0 1.7 1.3 1 0 0 1 1 1 0 Universal stress protein family Paf1 PF03985.13 EWM22225.1 - 0.092 11.7 8.2 0.11 11.5 8.2 1.1 1 0 0 1 1 1 0 Paf1 NOA36 PF06524.12 EWM22225.1 - 5.2 6.3 7.6 7 5.9 7.6 1.2 1 0 0 1 1 1 0 NOA36 protein DUF4637 PF15470.6 EWM22225.1 - 5.3 6.7 13.2 7.8 6.2 13.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DNA_pol_phi PF04931.13 EWM22225.1 - 6.8 4.7 9.9 8.4 4.3 9.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi DTW PF03942.15 EWM22226.1 - 4.9e-10 39.4 0.0 6.3e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 DTW domain DUF202 PF02656.15 EWM22227.1 - 0.52 10.8 4.2 1.2 9.6 4.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF202) LMWPc PF01451.21 EWM22228.1 - 2.3e-19 70.2 0.0 3.5e-19 69.6 0.0 1.3 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Ank_2 PF12796.7 EWM22229.1 - 7.4e-22 77.7 0.1 6.2e-10 39.5 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EWM22229.1 - 1.8e-19 69.8 0.5 1.5e-11 44.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EWM22229.1 - 1.4e-17 63.2 0.3 5.5e-05 23.4 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 EWM22229.1 - 2.7e-16 58.0 0.6 0.0022 18.4 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EWM22229.1 - 3.2e-11 43.3 1.4 2.3e-06 27.8 0.2 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EWM22232.1 - 3.3e-21 75.1 0.1 6.9e-09 35.8 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EWM22232.1 - 4.1e-17 62.5 0.0 2e-08 34.7 0.1 3.2 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EWM22232.1 - 3.2e-16 57.8 0.3 0.00014 22.0 0.0 5.9 7 0 0 7 7 7 3 Ankyrin repeat Ank_4 PF13637.6 EWM22232.1 - 6.7e-15 55.3 0.1 2e-06 28.3 0.0 4.0 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EWM22232.1 - 2.6e-13 49.7 0.1 0.00023 21.5 0.1 4.8 4 0 0 4 4 4 2 Ankyrin repeat TB2_DP1_HVA22 PF03134.19 EWM22232.1 - 2.5e-05 24.1 0.1 6.9e-05 22.7 0.0 1.8 1 1 1 2 2 2 1 TB2/DP1, HVA22 family ADK PF00406.22 EWM22233.1 - 2.1e-11 44.1 0.0 3e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EWM22233.1 - 1.1e-10 42.0 0.0 1.6e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EWM22233.1 - 0.0015 19.1 0.0 0.0021 18.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 EWM22233.1 - 0.018 15.3 0.0 0.028 14.7 0.0 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Cytidylate_kin PF02224.18 EWM22233.1 - 0.027 14.2 0.1 0.035 13.8 0.1 1.1 1 0 0 1 1 1 0 Cytidylate kinase Zeta_toxin PF06414.12 EWM22233.1 - 0.054 12.8 0.0 0.073 12.3 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin Phytochelatin PF05023.14 EWM22234.1 - 1.6e-77 259.5 0.0 4.8e-77 258.0 0.0 1.7 1 1 0 1 1 1 1 Phytochelatin synthase LrgB PF04172.16 EWM22236.1 - 2.2e-42 145.0 14.5 2.2e-42 145.0 14.5 1.5 2 0 0 2 2 2 1 LrgB-like family TLD PF07534.16 EWM22237.1 - 4.2e-23 82.1 0.0 9.3e-23 81.0 0.0 1.6 1 1 0 1 1 1 1 TLD RhoGAP PF00620.27 EWM22237.1 - 2.7e-06 27.3 0.0 4.9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain ELMO_CED12 PF04727.13 EWM22237.1 - 0.00026 21.2 0.1 0.00072 19.7 0.0 1.7 2 0 0 2 2 2 1 ELMO/CED-12 family RUN PF02759.19 EWM22238.1 - 2e-09 37.5 0.0 2.7e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 RUN domain Glyoxalase PF00903.25 EWM22242.1 - 1.5e-36 125.4 0.0 2.7e-18 66.4 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EWM22242.1 - 1.8e-12 47.5 0.0 2.6e-05 24.5 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EWM22242.1 - 1.1e-08 35.8 0.0 0.00082 20.1 0.0 3.1 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 EWM22242.1 - 0.018 15.2 0.0 0.25 11.4 0.0 2.4 2 0 0 2 2 2 0 Glyoxalase-like domain Glyoxalase_2 PF12681.7 EWM22242.1 - 0.07 13.1 0.0 17 5.3 0.0 3.3 3 0 0 3 3 3 0 Glyoxalase-like domain DUF3081 PF11280.8 EWM22242.1 - 0.13 12.1 0.0 22 4.9 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3081) CppA_N PF14506.6 EWM22242.1 - 0.17 12.0 0.0 10 6.2 0.0 2.3 2 0 0 2 2 2 0 CppA N-terminal CAT_RBD PF03123.15 EWM22242.1 - 0.23 11.4 0.1 18 5.4 0.0 2.9 4 0 0 4 4 4 0 CAT RNA binding domain LAP1C PF05609.12 EWM22243.1 - 0.044 12.9 5.6 0.052 12.6 5.6 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) MTA_R1 PF17226.2 EWM22243.1 - 0.066 13.4 1.0 0.13 12.5 1.0 1.5 1 0 0 1 1 1 0 MTA R1 domain CDC45 PF02724.14 EWM22243.1 - 0.55 8.5 10.3 0.63 8.3 10.3 1.0 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.11 EWM22243.1 - 0.6 10.1 7.0 0.66 10.0 6.3 1.3 1 1 0 1 1 1 0 RXT2-like, N-terminal Myc_N PF01056.18 EWM22243.1 - 0.78 9.6 5.4 1.1 9.1 5.4 1.2 1 0 0 1 1 1 0 Myc amino-terminal region TMEM119 PF15724.5 EWM22243.1 - 1.8 8.6 5.7 2.5 8.1 5.7 1.2 1 0 0 1 1 1 0 TMEM119 family NAD_binding_10 PF13460.6 EWM22245.1 - 4.2e-31 108.3 0.1 9.7e-30 103.8 0.1 2.3 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EWM22245.1 - 2.7e-10 40.2 0.4 1.2e-08 34.8 0.1 2.8 2 2 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 EWM22245.1 - 3.2e-09 36.6 0.0 2.2e-05 24.0 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EWM22245.1 - 1.8e-08 34.2 0.1 2.6e-05 23.8 0.0 2.3 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EWM22245.1 - 1.9e-07 30.4 0.0 0.0041 16.2 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EWM22245.1 - 1.8e-05 24.0 0.1 0.34 10.0 0.0 2.9 2 1 1 3 3 3 2 Male sterility protein KR PF08659.10 EWM22245.1 - 0.001 19.0 0.1 0.0017 18.3 0.1 1.3 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 EWM22245.1 - 0.0056 15.8 0.0 0.41 9.7 0.0 2.6 3 0 0 3 3 3 1 RmlD substrate binding domain adh_short PF00106.25 EWM22245.1 - 0.032 13.7 0.1 0.076 12.5 0.0 1.6 2 0 0 2 2 2 0 short chain dehydrogenase Shikimate_DH PF01488.20 EWM22245.1 - 0.042 13.9 0.0 0.085 12.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 EWM22245.1 - 0.046 13.9 0.3 0.098 12.8 0.1 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.18 EWM22245.1 - 0.17 12.1 0.1 0.56 10.5 0.1 1.9 1 1 0 1 1 1 0 TrkA-N domain Polysacc_synt_2 PF02719.15 EWM22245.1 - 0.24 10.5 0.0 10 5.2 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Sel1 PF08238.12 EWM22248.1 - 0.0017 19.0 15.3 0.21 12.3 2.0 5.6 6 0 0 6 6 6 2 Sel1 repeat DUF2561 PF10812.8 EWM22248.1 - 0.064 13.3 0.5 0.35 10.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) PAP_fibrillin PF04755.12 EWM22249.1 - 1.8e-18 67.2 0.1 7.8e-17 61.9 0.1 2.1 1 1 0 1 1 1 1 PAP_fibrillin Asp PF00026.23 EWM22250.1 - 1.3e-98 330.3 0.0 1.6e-98 330.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EWM22250.1 - 2.4e-10 40.9 1.3 2.3e-05 24.7 0.0 2.2 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EWM22250.1 - 7.4e-05 23.3 0.0 0.035 14.7 0.0 3.0 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 EWM22250.1 - 0.022 15.3 0.0 3.9 8.1 0.0 2.9 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease TRAM_LAG1_CLN8 PF03798.16 EWM22253.1 - 3.8e-08 33.3 11.9 8e-08 32.3 11.9 1.5 1 1 0 1 1 1 1 TLC domain ELO PF01151.18 EWM22253.1 - 0.00089 18.9 3.4 0.00089 18.9 3.4 1.5 2 0 0 2 2 2 1 GNS1/SUR4 family Trehalase PF01204.18 EWM22255.1 - 0.52 9.1 2.4 0.72 8.6 2.4 1.1 1 0 0 1 1 1 0 Trehalase Gal-3-0_sulfotr PF06990.11 EWM22256.1 - 1.2e-08 34.2 0.8 0.0012 17.8 0.1 2.2 2 0 0 2 2 2 2 Galactose-3-O-sulfotransferase DUF3209 PF11483.8 EWM22256.1 - 0.054 14.0 0.3 7.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3209) KfrA_N PF11740.8 EWM22257.1 - 0.042 14.5 13.1 0.42 11.3 3.2 2.3 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term MAGE_N PF12440.8 EWM22257.1 - 0.67 10.7 10.7 0.31 11.8 5.3 2.7 1 1 2 3 3 3 0 Melanoma associated antigen family N terminal GST_N_2 PF13409.6 EWM22258.1 - 2.9e-09 37.1 0.5 6.3e-09 36.0 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EWM22258.1 - 8.8e-09 35.7 0.0 3.1e-08 33.9 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EWM22258.1 - 1.3e-08 35.0 0.1 2.2e-06 27.9 0.0 2.7 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EWM22258.1 - 0.00015 21.7 0.1 0.00029 20.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EWM22258.1 - 0.0005 20.6 0.0 0.001 19.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Beta-lactamase PF00144.24 EWM22259.1 - 4.2e-51 174.2 0.4 1.2e-50 172.7 0.4 1.6 1 1 0 1 1 1 1 Beta-lactamase PPL5 PF18168.1 EWM22260.1 - 0.68 9.2 3.1 1.1 8.5 3.1 1.3 1 0 0 1 1 1 0 Prim-pol family 5 PTPS PF01242.19 EWM22261.1 - 1.1e-19 70.6 0.0 1.3e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase ATP_transf PF09830.9 EWM22262.1 - 3.1e-13 49.7 0.0 6.4e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4922 PF16269.5 EWM22262.1 - 0.1 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4922) Cupin_4 PF08007.12 EWM22263.1 - 3.1e-43 148.5 0.0 4.3e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 EWM22263.1 - 2.7e-06 27.3 0.0 0.0009 19.0 0.0 2.4 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 EWM22263.1 - 0.0007 19.3 0.1 0.0069 16.1 0.0 2.5 3 0 0 3 3 3 1 Cupin domain Cupin_1 PF00190.22 EWM22263.1 - 0.027 14.1 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 Cupin SRP54 PF00448.22 EWM22264.1 - 8.1e-07 28.9 0.2 1.1e-06 28.5 0.2 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 EWM22264.1 - 3.9e-05 23.0 0.2 4.9e-05 22.7 0.2 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.6 EWM22264.1 - 0.0064 16.1 0.1 0.0069 16.0 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EWM22264.1 - 0.0086 16.2 0.1 0.012 15.8 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EWM22264.1 - 0.017 15.7 0.1 0.024 15.2 0.1 1.2 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EWM22264.1 - 0.025 14.6 0.0 0.025 14.6 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE APS_kinase PF01583.20 EWM22264.1 - 0.04 13.8 0.0 0.056 13.3 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_30 PF13604.6 EWM22264.1 - 0.042 13.6 0.5 0.049 13.3 0.5 1.1 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.18 EWM22264.1 - 0.064 12.6 0.0 0.073 12.4 0.0 1.1 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_16 PF13191.6 EWM22264.1 - 0.064 13.6 0.0 0.07 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EWM22264.1 - 0.093 13.0 0.1 0.13 12.5 0.1 1.3 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EWM22264.1 - 0.1 12.5 0.3 0.18 11.7 0.3 1.3 1 0 0 1 1 1 0 NACHT domain Sigma54_activ_2 PF14532.6 EWM22264.1 - 0.11 12.6 0.1 0.13 12.3 0.1 1.1 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.29 EWM22264.1 - 0.15 12.5 0.3 0.35 11.3 0.2 1.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Arf PF00025.21 EWM22264.1 - 0.15 11.5 0.1 0.19 11.2 0.1 1.3 1 1 0 1 1 1 0 ADP-ribosylation factor family AAA_24 PF13479.6 EWM22264.1 - 0.17 11.6 0.1 0.26 11.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 EWM22264.1 - 0.18 11.5 0.1 0.29 10.8 0.1 1.4 1 1 0 1 1 1 0 Thymidylate kinase SRAP PF02586.14 EWM22265.1 - 2.2e-56 190.9 0.0 2.9e-56 190.5 0.0 1.2 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) C2 PF00168.30 EWM22266.1 - 0.011 16.0 0.0 0.025 14.8 0.0 1.6 1 0 0 1 1 1 0 C2 domain FAM176 PF14851.6 EWM22266.1 - 0.14 11.8 1.4 0.22 11.1 1.4 1.2 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 EWM22266.1 - 0.25 10.6 1.6 0.38 10.0 1.6 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 EWM22266.1 - 2.2 6.3 7.4 2.9 5.9 7.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi RecC_C PF17946.1 EWM22267.1 - 0.045 13.5 0.0 0.048 13.4 0.0 1.0 1 0 0 1 1 1 0 RecC C-terminal domain SRP_SPB PF02978.19 EWM22268.1 - 1.1e-18 67.6 2.7 1.1e-18 67.6 2.7 1.7 2 0 0 2 2 2 1 Signal peptide binding domain Mis14 PF08641.12 EWM22268.1 - 0.22 11.8 0.1 0.22 11.8 0.1 1.8 2 0 0 2 2 2 0 Kinetochore protein Mis14 like Ribosomal_L17 PF01196.19 EWM22269.1 - 2.7e-31 108.3 0.1 4.8e-31 107.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L17 MOZART1 PF12554.8 EWM22270.1 - 0.21 11.4 0.1 0.31 10.8 0.1 1.2 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated PDZ PF00595.24 EWM22271.1 - 4.2e-05 23.8 0.0 8.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain SUIM_assoc PF16619.5 EWM22271.1 - 0.00049 20.1 0.2 0.0005 20.1 0.2 1.3 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 PDZ_6 PF17820.1 EWM22271.1 - 0.006 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Med15 PF09606.10 EWM22271.1 - 0.018 13.8 6.3 0.02 13.6 6.3 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RAB3GAP2_N PF14655.6 EWM22271.1 - 0.076 12.3 0.2 0.11 11.8 0.2 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Rav1p_C PF12234.8 EWM22272.1 - 5.1e-18 64.8 0.2 5.9e-18 64.6 0.2 1.0 1 0 0 1 1 1 1 RAVE protein 1 C terminal MOR2-PAG1_mid PF14228.6 EWM22272.1 - 0.041 11.5 0.0 0.049 11.3 0.0 1.0 1 0 0 1 1 1 0 Cell morphogenesis central region B12D PF06522.11 EWM22277.1 - 0.002 17.9 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit adh_short PF00106.25 EWM22278.1 - 3.7e-18 65.7 0.0 4.4e-18 65.4 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EWM22278.1 - 2.9e-13 49.9 0.1 3.4e-13 49.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM22278.1 - 0.00012 22.0 0.0 0.00014 21.8 0.0 1.1 1 0 0 1 1 1 1 KR domain CNDH2_C PF16858.5 EWM22279.1 - 0.39 10.6 7.6 0.52 10.1 7.6 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Pkinase PF00069.25 EWM22280.1 - 3.9e-68 229.7 0.0 5.3e-68 229.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM22280.1 - 3e-33 115.2 0.0 4.1e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EWM22280.1 - 2.5e-05 24.9 0.6 4.6e-05 24.0 0.6 1.4 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 EWM22280.1 - 4.8e-05 22.8 0.0 7.6e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EWM22280.1 - 0.0011 18.6 0.3 0.84 9.2 0.0 2.7 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 EWM22280.1 - 0.014 14.3 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EWM22280.1 - 0.058 12.7 0.0 0.19 11.0 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family ORC6 PF05460.13 EWM22281.1 - 0.089 12.0 0.4 0.087 12.1 0.4 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SCP2 PF02036.17 EWM22282.1 - 3.6e-25 88.4 0.4 4e-25 88.2 0.4 1.0 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 EWM22282.1 - 1.3e-05 25.4 0.1 1.6e-05 25.2 0.1 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Helicase_C PF00271.31 EWM22283.1 - 1.2e-05 25.6 0.0 3.1e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ORC3_N PF07034.11 EWM22283.1 - 0.0082 15.3 0.0 0.24 10.5 0.0 2.1 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus DEAD PF00270.29 EWM22284.1 - 0.021 14.6 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase HATPase_c_3 PF13589.6 EWM22287.1 - 1.1e-13 51.2 0.3 2.7e-13 49.9 0.1 1.8 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EWM22287.1 - 7.1e-07 29.7 0.0 1.2e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PetG PF02529.15 EWM22288.1 - 0.037 13.9 0.5 0.078 12.8 0.5 1.5 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 Podoplanin PF05808.11 EWM22288.1 - 0.14 12.3 0.0 0.37 10.9 0.0 1.7 1 0 0 1 1 1 0 Podoplanin Herpes_PAP PF03325.13 EWM22288.1 - 0.17 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus polymerase accessory protein PQQ_3 PF13570.6 EWM22288.1 - 0.31 11.6 7.2 9.4 6.9 0.1 4.5 5 0 0 5 5 5 0 PQQ-like domain MutL_C PF08676.11 EWM22290.1 - 6e-24 84.5 0.0 1.2e-23 83.6 0.0 1.4 1 1 0 1 1 1 1 MutL C terminal dimerisation domain GDI PF00996.18 EWM22291.1 - 2e-82 277.0 0.3 2.2e-82 276.9 0.3 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor TypeIII_RM_meth PF12564.8 EWM22291.1 - 0.044 13.9 0.0 0.36 11.0 0.0 2.2 2 0 0 2 2 2 0 Type III restriction/modification enzyme methylation subunit Methyltransf_16 PF10294.9 EWM22292.1 - 3.4e-05 23.6 0.0 0.0022 17.8 0.0 2.4 2 0 0 2 2 2 2 Lysine methyltransferase Toxin_22 PF08092.11 EWM22294.1 - 0.017 15.2 0.3 0.094 12.8 0.0 2.2 2 0 0 2 2 2 0 Magi peptide toxin family DUF1279 PF06916.13 EWM22297.1 - 0.00019 21.9 0.0 0.00031 21.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Beach PF02138.18 EWM22298.1 - 2.4e-33 115.7 0.2 2.8e-33 115.5 0.2 1.0 1 0 0 1 1 1 1 Beige/BEACH domain Beach PF02138.18 EWM22300.1 - 4.2e-35 121.5 0.0 5.8e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Beige/BEACH domain TSKS PF15358.6 EWM22301.1 - 0.29 9.5 0.5 0.35 9.2 0.5 1.1 1 0 0 1 1 1 0 Testis-specific serine kinase substrate Adaptin_N PF01602.20 EWM22302.1 - 6.8e-24 84.3 0.5 8.7e-24 84.0 0.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region AbiJ_NTD5 PF18865.1 EWM22302.1 - 0.086 12.7 0.0 0.26 11.1 0.0 1.8 2 0 0 2 2 2 0 AbiJ N-terminal domain 5 PEPCK_N PF17297.2 EWM22302.1 - 0.12 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase N-terminal domain DUF5346 PF17281.2 EWM22303.1 - 2 8.5 6.0 5.9 7.0 6.0 1.9 1 1 0 1 1 1 0 Family of unknown function (DUF5346) PhzC-PhzF PF02567.16 EWM22304.1 - 6.8e-57 193.1 0.0 2.2e-34 119.2 0.0 2.9 3 1 0 3 3 3 2 Phenazine biosynthesis-like protein Acetyltransf_1 PF00583.25 EWM22304.1 - 3.3e-07 30.5 0.1 8.2e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EWM22304.1 - 0.00011 22.6 0.0 0.00043 20.7 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EWM22304.1 - 0.00013 21.9 0.0 0.00024 21.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EWM22304.1 - 0.014 15.1 0.3 0.047 13.4 0.0 1.9 2 1 1 3 3 3 0 Acetyltransferase (GNAT) domain Pro_racemase PF05544.11 EWM22304.1 - 0.074 12.1 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Proline racemase Acetyltransf_CG PF14542.6 EWM22304.1 - 0.15 12.2 0.1 0.95 9.6 0.0 2.4 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Adaptin_N PF01602.20 EWM22305.1 - 1.1e-06 27.5 0.0 1.2e-06 27.4 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Inj_translocase PF16928.5 EWM22305.1 - 0.12 11.8 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome Coatomer_g_Cpla PF16381.5 EWM22306.1 - 6.4e-30 103.7 0.0 8.1e-30 103.3 0.0 1.1 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform COP-gamma_platf PF08752.10 EWM22306.1 - 4.4e-12 46.4 0.0 7.4e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Alpha_adaptin_C PF02296.16 EWM22306.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.5 1 1 0 1 1 1 0 Alpha adaptin AP2, C-terminal domain CH PF00307.31 EWM22307.1 - 0.00042 20.5 0.0 0.36 11.0 0.0 2.7 3 0 0 3 3 3 2 Calponin homology (CH) domain DUF1990 PF09348.10 EWM22308.1 - 1e-21 77.6 0.2 1.9e-21 76.7 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1990) VWA_2 PF13519.6 EWM22309.1 - 0.00076 20.1 0.0 0.0018 18.9 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain Vint PF14623.6 EWM22310.1 - 1.6e-12 47.6 0.0 2.4e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Hint-domain PT PF04886.12 EWM22310.1 - 1.5e-07 30.9 126.8 79 2.9 47.4 4.7 1 1 1 2 2 2 0 PT repeat Hint PF01079.20 EWM22310.1 - 0.0004 20.0 0.0 0.00064 19.3 0.0 1.2 1 0 0 1 1 1 1 Hint module Hom_end_hint PF05203.16 EWM22310.1 - 0.035 14.1 0.0 0.043 13.8 0.0 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint Hint_2 PF13403.6 EWM22310.1 - 0.072 13.4 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 Hint domain IL32 PF15225.6 EWM22311.1 - 0.094 13.1 1.8 0.23 11.8 1.8 1.6 1 0 0 1 1 1 0 Interleukin 32 PGA2 PF07543.12 EWM22312.1 - 0.28 11.1 7.6 0.25 11.3 5.9 1.8 2 0 0 2 2 2 0 Protein trafficking PGA2 RNase_PH PF01138.21 EWM22313.1 - 6.6e-39 133.4 0.0 1.5e-21 77.3 0.0 2.4 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EWM22313.1 - 1.7e-18 66.4 0.4 3.5e-15 55.8 0.0 2.5 2 0 0 2 2 2 2 3' exoribonuclease family, domain 2 Trp_ring PF18669.1 EWM22314.1 - 0.046 13.9 0.1 0.066 13.4 0.1 1.3 1 0 0 1 1 1 0 Trimeric autotransporter adhesin Trp ring domain tRNA-synt_2c PF01411.19 EWM22315.1 - 9.7e-186 618.5 0.0 1.2e-185 618.2 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (A) bZIP_1 PF00170.21 EWM22316.1 - 0.00013 22.0 3.2 0.00026 21.0 3.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EWM22316.1 - 0.4 10.8 7.8 0.06 13.4 3.1 2.0 2 0 0 2 2 2 0 Basic region leucine zipper AhpC-TSA PF00578.21 EWM22317.1 - 9.9e-28 96.5 0.0 1.5e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EWM22317.1 - 1.3e-19 70.4 0.0 2e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 Redoxin Trehalose_PPase PF02358.16 EWM22318.1 - 3.2e-56 190.1 0.0 4.2e-56 189.7 0.0 1.1 1 0 0 1 1 1 1 Trehalose-phosphatase MTD PF01993.18 EWM22318.1 - 0.095 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase Kdo PF06293.14 EWM22319.1 - 7.7e-08 31.9 0.0 1.1e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EWM22319.1 - 3.2e-06 26.7 0.0 4.2e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EWM22319.1 - 4.9e-06 26.6 0.3 0.016 15.2 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 EWM22319.1 - 3.8e-05 23.4 0.1 6.5e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 EWM22319.1 - 0.00056 19.3 0.0 0.00089 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EcKinase PF02958.20 EWM22319.1 - 0.06 12.7 0.0 0.13 11.6 0.0 1.6 1 1 0 1 1 1 0 Ecdysteroid kinase YrbL-PhoP_reg PF10707.9 EWM22319.1 - 0.091 12.3 0.4 1.3 8.5 0.0 2.5 2 1 1 3 3 3 0 PhoP regulatory network protein YrbL NOB1_Zn_bind PF08772.11 EWM22320.1 - 5.2e-21 74.6 0.4 1e-20 73.6 0.4 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_15 PF17032.5 EWM22320.1 - 0.0033 18.2 0.3 0.005 17.6 0.3 1.3 1 0 0 1 1 1 1 zinc-ribbon family DZR PF12773.7 EWM22320.1 - 0.0042 17.1 0.2 0.0086 16.1 0.2 1.5 1 0 0 1 1 1 1 Double zinc ribbon zf-NADH-PPase PF09297.11 EWM22320.1 - 0.0045 16.6 4.4 0.49 10.1 0.3 2.5 2 0 0 2 2 2 2 NADH pyrophosphatase zinc ribbon domain Prok-RING_1 PF14446.6 EWM22320.1 - 0.034 14.1 0.2 0.06 13.3 0.2 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 HypA PF01155.19 EWM22320.1 - 0.049 13.7 0.3 0.076 13.0 0.3 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 EWM22320.1 - 0.058 12.8 1.4 0.13 11.7 1.4 1.6 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 EWM22320.1 - 0.06 13.1 1.1 0.06 13.1 1.1 1.7 2 0 0 2 2 2 0 zinc-ribbon domain Cript PF10235.9 EWM22320.1 - 0.073 13.6 0.1 0.14 12.8 0.1 1.4 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT A2L_zn_ribbon PF08792.10 EWM22320.1 - 0.11 12.2 0.6 0.23 11.2 0.6 1.5 1 0 0 1 1 1 0 A2L zinc ribbon domain DUF35_N PF12172.8 EWM22320.1 - 0.18 11.7 2.7 0.54 10.2 2.7 1.8 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Ribosomal_L22e PF01776.17 EWM22321.1 - 6.3e-46 155.3 2.1 7.8e-46 155.0 2.1 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF5374 PF17344.2 EWM22321.1 - 0.17 11.9 0.0 0.44 10.5 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5374) Pyridox_oxase_2 PF12766.7 EWM22322.1 - 4.2e-22 78.6 2.1 7.1e-22 77.9 0.6 2.1 2 1 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 EWM22322.1 - 0.00049 20.2 0.0 0.0011 19.1 0.0 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Sugar_tr PF00083.24 EWM22323.1 - 6.5e-22 78.0 20.2 6.6e-12 45.0 7.1 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EWM22323.1 - 2.5e-10 39.8 38.0 2.2e-09 36.7 9.5 3.7 2 1 1 3 3 3 3 Major Facilitator Superfamily SelK_SelG PF10961.8 EWM22323.1 - 0.26 11.9 0.1 0.26 11.9 0.1 2.2 2 0 0 2 2 2 0 Selenoprotein SelK_SelG MFS_1_like PF12832.7 EWM22323.1 - 1.5 7.6 9.4 0.14 11.0 2.8 2.1 2 0 0 2 2 2 0 MFS_1 like family Stomagen PF16851.5 EWM22324.1 - 0.024 14.6 0.2 0.035 14.1 0.2 1.4 1 0 0 1 1 1 0 Stomagen Antistasin PF02822.14 EWM22324.1 - 0.027 15.1 0.1 0.063 13.9 0.1 1.6 1 0 0 1 1 1 0 Antistasin family zf-RING_UBOX PF13445.6 EWM22325.1 - 2.8e-08 33.6 7.1 6.3e-08 32.5 7.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EWM22325.1 - 2.8e-07 30.3 9.1 5.1e-07 29.4 9.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EWM22325.1 - 3.6e-07 30.4 9.7 8.3e-07 29.2 9.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EWM22325.1 - 5e-07 29.5 10.3 9.4e-07 28.6 10.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EWM22325.1 - 9.1e-07 28.9 8.2 1.9e-06 27.9 8.2 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EWM22325.1 - 5.4e-06 26.1 9.1 1e-05 25.3 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EWM22325.1 - 1.7e-05 24.6 9.2 3.8e-05 23.5 9.0 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EWM22325.1 - 6.2e-05 22.9 10.9 0.00012 22.0 10.1 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.6 EWM22325.1 - 0.022 14.6 7.2 0.042 13.7 6.5 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 EWM22325.1 - 0.13 12.4 6.4 0.27 11.4 6.4 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 EWM22325.1 - 0.14 12.5 5.3 0.34 11.2 5.3 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EWM22325.1 - 0.17 11.7 5.0 0.47 10.2 5.0 1.9 1 0 0 1 1 1 0 RING-like zinc finger PP28 PF10252.9 EWM22326.1 - 2.3e-15 56.8 15.3 2.3e-15 56.8 15.3 2.3 2 0 0 2 2 2 1 Casein kinase substrate phosphoprotein PP28 SAP PF02037.27 EWM22326.1 - 4.6e-08 32.6 3.0 8.7e-08 31.7 3.0 1.5 1 0 0 1 1 1 1 SAP domain DUF4407 PF14362.6 EWM22326.1 - 6.9 5.9 8.3 11 5.2 8.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3228 PF11539.8 EWM22327.1 - 3.9e-56 189.7 0.0 5e-56 189.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) zf-C2H2_3rep PF18868.1 EWM22328.1 - 0.0043 17.7 1.8 0.0052 17.5 0.9 1.6 1 1 1 2 2 2 1 Zinc finger C2H2-type, 3 repeats Eapp_C PF10238.9 EWM22328.1 - 0.0096 16.0 4.3 0.018 15.2 4.3 1.5 1 1 0 1 1 1 1 E2F-associated phosphoprotein Actin_micro PF17003.5 EWM22328.1 - 0.069 12.3 0.0 0.08 12.1 0.0 1.1 1 0 0 1 1 1 0 Putative actin-like family C1_4 PF07975.12 EWM22328.1 - 0.069 13.4 0.7 0.15 12.3 0.7 1.9 1 1 0 1 1 1 0 TFIIH C1-like domain Apt1 PF10351.9 EWM22328.1 - 0.12 11.2 25.8 0.12 11.2 25.8 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.14 EWM22328.1 - 0.16 10.3 14.0 0.17 10.2 14.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EWM22328.1 - 0.28 9.3 9.9 0.26 9.4 9.9 1.0 1 0 0 1 1 1 0 Nop14-like family Macoilin PF09726.9 EWM22328.1 - 0.44 9.0 24.1 0.43 9.1 24.1 1.0 1 0 0 1 1 1 0 Macoilin family Menin PF05053.13 EWM22328.1 - 1.4 7.2 9.4 1.5 7.1 9.4 1.0 1 0 0 1 1 1 0 Menin HSD3 PF15244.6 EWM22328.1 - 2.1 7.8 20.2 2.4 7.6 20.2 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 SPX PF03105.19 EWM22328.1 - 2.5 7.9 24.5 2.6 7.9 24.5 1.1 1 0 0 1 1 1 0 SPX domain NPR3 PF03666.13 EWM22328.1 - 2.9 6.6 14.9 3.1 6.5 14.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 EWM22328.1 - 3.6 6.2 15.6 3.9 6.2 15.6 1.0 1 0 0 1 1 1 0 Presenilin CAML PF14963.6 EWM22328.1 - 5.7 7.0 11.5 5.7 7.0 11.5 1.1 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand SOBP PF15279.6 EWM22328.1 - 7.3 7.1 13.8 7.7 7.0 13.8 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Zip PF02535.22 EWM22328.1 - 9.2 5.4 7.3 9.5 5.3 7.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter eIF-3_zeta PF05091.12 EWM22330.1 - 1.1e-135 453.6 0.0 9.6e-82 275.6 0.0 2.0 2 0 0 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CDC45 PF02724.14 EWM22330.1 - 2.6 6.2 5.8 4.2 5.5 5.8 1.2 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 EWM22330.1 - 4.7 6.7 8.7 8.2 5.9 8.7 1.3 1 0 0 1 1 1 0 PPP4R2 Aa_trans PF01490.18 EWM22331.1 - 8.6e-15 54.4 12.0 8.6e-15 54.4 12.0 1.5 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein Cu_amine_oxid PF01179.20 EWM22333.1 - 7.1e-152 506.0 0.0 8.4e-152 505.8 0.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 EWM22333.1 - 3.3e-11 43.5 0.1 9.4e-11 42.0 0.0 1.8 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 EWM22333.1 - 8.4e-09 35.6 0.1 2.5e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Abhydrolase_6 PF12697.7 EWM22334.1 - 3.3e-09 37.7 2.0 5.7e-09 36.9 2.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EWM22334.1 - 1.5e-06 28.0 0.0 0.0025 17.5 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Thioesterase PF00975.20 EWM22334.1 - 0.0088 16.2 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 EWM22334.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_M76 PF09768.9 EWM22335.1 - 3.7e-22 78.9 1.2 4.6e-22 78.6 0.3 1.6 2 0 0 2 2 2 1 Peptidase M76 family Peptidase_M91 PF14891.6 EWM22335.1 - 0.0013 19.1 0.0 0.0021 18.4 0.0 1.2 1 0 0 1 1 1 1 Effector protein BSP PF04450.12 EWM22335.1 - 0.15 11.8 0.1 0.24 11.2 0.1 1.2 1 0 0 1 1 1 0 Peptidase of plants and bacteria MHB PF16525.5 EWM22336.1 - 0.056 13.7 0.1 0.97 9.7 0.1 2.6 2 0 0 2 2 2 0 Haemophore, haem-binding GST_C_3 PF14497.6 EWM22337.1 - 1.2e-18 67.1 0.1 1.9e-18 66.5 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EWM22337.1 - 4.7e-11 42.8 0.0 9.6e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EWM22337.1 - 1.5e-07 31.7 0.0 3.2e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EWM22337.1 - 1.2e-05 25.3 0.0 2.6e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EWM22337.1 - 0.00054 20.3 0.0 0.0011 19.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EWM22337.1 - 0.047 14.0 0.0 0.14 12.5 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Peptidase_M16_M PF16187.5 EWM22338.1 - 5.2e-42 144.1 0.0 1.1e-31 110.2 0.0 2.2 1 1 1 2 2 2 2 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 EWM22338.1 - 5.5e-33 114.0 0.0 1.7e-32 112.5 0.0 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EWM22338.1 - 6.7e-28 97.9 0.0 1e-15 58.2 0.0 2.5 2 0 0 2 2 2 2 Peptidase M16 inactive domain ACT_7 PF13840.6 EWM22339.1 - 6.8e-07 29.0 0.0 1.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 ACT domain ACT PF01842.25 EWM22339.1 - 0.059 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 ACT domain Tubulin PF00091.25 EWM22340.1 - 1.9e-40 139.2 0.0 2.9e-40 138.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 EWM22340.1 - 0.023 13.9 0.1 0.04 13.1 0.1 1.4 1 0 0 1 1 1 0 Tubulin like Vps52 PF04129.12 EWM22341.1 - 2.1e-127 426.0 0.2 9.7e-126 420.5 0.1 2.7 2 1 0 2 2 2 1 Vps52 / Sac2 family Sec3_C PF09763.9 EWM22341.1 - 8.7e-11 40.9 10.6 7.1e-10 37.9 5.9 2.7 2 1 0 2 2 2 2 Exocyst complex component Sec3 COG2 PF06148.11 EWM22341.1 - 0.017 15.2 0.7 0.062 13.4 0.7 1.9 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 COG6 PF06419.11 EWM22341.1 - 0.017 13.3 0.3 0.72 8.0 0.5 2.3 2 0 0 2 2 2 0 Conserved oligomeric complex COG6 UPF0449 PF15136.6 EWM22341.1 - 0.15 12.5 0.5 0.62 10.6 0.5 2.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Spc7 PF08317.11 EWM22341.1 - 0.29 10.0 3.4 0.66 8.8 3.4 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.12 EWM22341.1 - 0.48 10.5 2.4 0.94 9.5 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Cep57_MT_bd PF06657.13 EWM22341.1 - 1.5 9.3 5.2 1.2 9.7 1.1 2.6 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Piwi PF02171.17 EWM22342.1 - 4.7e-87 292.0 0.5 7e-87 291.5 0.5 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 EWM22342.1 - 1.6e-18 66.8 0.0 3.2e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 EWM22342.1 - 7.4e-18 65.5 0.0 1.6e-17 64.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 EWM22342.1 - 1.9e-12 46.7 0.1 5e-12 45.3 0.1 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoMid PF16487.5 EWM22342.1 - 2e-06 28.0 0.0 5.1e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 EWM22342.1 - 0.00072 19.8 0.0 0.0018 18.6 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain HU-DNA_bdg PF14848.6 EWM22342.1 - 0.2 11.7 1.4 0.26 11.3 0.2 1.8 2 0 0 2 2 2 0 DNA-binding domain NDUFA12 PF05071.16 EWM22343.1 - 8.5e-19 68.2 3.3 3.1e-18 66.4 3.3 1.9 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Abhydrolase_1 PF00561.20 EWM22344.1 - 5.9e-15 55.6 0.0 1.3e-13 51.2 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EWM22344.1 - 6.8e-13 49.7 6.9 6.8e-13 49.7 6.9 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EWM22344.1 - 4e-09 36.1 0.0 6e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 EWM22344.1 - 0.00099 19.1 0.0 0.008 16.1 0.0 2.0 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 EWM22344.1 - 0.0031 17.1 0.0 0.52 9.8 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family TDH PF03347.13 EWM22346.1 - 0.051 13.1 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 Vibrio thermostable direct hemolysin DUF3324 PF11797.8 EWM22346.1 - 0.16 11.9 0.0 0.17 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function C-terminal (DUF3324) DUF2040 PF09745.9 EWM22348.1 - 1.3e-30 105.9 23.3 1.3e-30 105.9 23.3 2.2 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) DUF4266 PF14086.6 EWM22348.1 - 0.85 10.6 6.2 0.86 10.6 0.7 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4266) UDPG_MGDP_dh_C PF03720.15 EWM22348.1 - 1.1 9.7 4.6 5.8 7.4 4.6 2.2 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain DUF773 PF05600.12 EWM22349.1 - 1.3e-85 288.1 0.5 4.1e-84 283.2 0.5 2.0 1 1 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 ARA70 PF12489.8 EWM22349.1 - 0.014 15.6 0.9 0.032 14.4 0.1 1.9 2 0 0 2 2 2 0 Nuclear coactivator Tropomyosin_1 PF12718.7 EWM22349.1 - 0.16 12.1 4.3 1.6 8.9 0.0 2.9 3 0 0 3 3 3 0 Tropomyosin like Adaptin_binding PF10199.9 EWM22349.1 - 0.29 11.7 4.2 3.8 8.1 0.1 2.7 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Prefoldin_2 PF01920.20 EWM22349.1 - 0.71 9.9 4.1 7.8 6.5 0.0 3.4 3 1 1 4 4 4 0 Prefoldin subunit Abhydrolase_5 PF12695.7 EWM22350.1 - 3.6e-08 33.4 0.0 7.8e-08 32.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EWM22350.1 - 5e-07 29.2 0.0 5.3e-06 25.9 0.0 2.3 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EWM22350.1 - 0.005 17.5 11.0 0.022 15.4 6.7 3.3 1 1 1 2 2 2 1 Alpha/beta hydrolase family IlvC PF01450.19 EWM22351.1 - 2e-42 144.9 0.4 3.4e-33 115.0 0.2 2.2 2 0 0 2 2 2 2 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.12 EWM22351.1 - 3.3e-32 111.3 0.0 5.8e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain DUF998 PF06197.13 EWM22351.1 - 0.081 12.5 0.4 0.16 11.5 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF998) T2SSF PF00482.23 EWM22351.1 - 0.14 12.1 0.0 4.6 7.2 0.0 2.7 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F VHS PF00790.19 EWM22352.1 - 2.8e-26 92.0 0.3 5.3e-26 91.1 0.1 1.5 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 EWM22352.1 - 1e-06 28.9 1.8 1.5e-05 25.2 0.1 2.4 2 0 0 2 2 2 1 GAT domain ENTH PF01417.20 EWM22352.1 - 0.00027 21.0 0.1 0.00052 20.1 0.1 1.4 1 0 0 1 1 1 1 ENTH domain TFIIA PF03153.13 EWM22352.1 - 7.1 6.5 18.7 14 5.6 18.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ald_Xan_dh_C2 PF02738.18 EWM22353.1 - 3.8e-190 633.0 1.2 5.3e-190 632.5 1.2 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 EWM22353.1 - 9.4e-46 155.7 0.7 1.8e-45 154.7 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 EWM22353.1 - 1.7e-30 105.6 0.3 4.3e-30 104.3 0.3 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 EWM22353.1 - 1.1e-27 96.2 0.0 2.8e-27 94.9 0.0 1.7 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.20 EWM22353.1 - 1.1e-26 92.6 0.1 2.7e-26 91.4 0.1 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 EWM22353.1 - 2.3e-08 33.9 0.5 2.3e-08 33.9 0.5 2.5 2 1 1 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain Glyco_transf_4 PF13439.6 EWM22354.1 - 5.7e-17 62.2 2.4 1.4e-16 61.0 2.4 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 EWM22354.1 - 1.2e-16 60.7 0.0 4.1e-16 59.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EWM22354.1 - 3.3e-16 59.9 0.0 8.3e-16 58.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EWM22354.1 - 0.021 15.3 6.3 0.23 11.9 6.3 2.3 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain adh_short PF00106.25 EWM22355.1 - 2.2e-28 99.1 0.0 1.6e-24 86.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EWM22355.1 - 1.1e-19 71.0 0.0 3e-16 59.7 0.0 2.4 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM22355.1 - 1.2e-06 28.5 0.0 1.9e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Ribosomal_L2 PF00181.23 EWM22355.1 - 0.017 15.1 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 Ribosomal Proteins L2, RNA binding domain Fructosamin_kin PF03881.14 EWM22357.1 - 6.1e-91 304.6 0.0 7.5e-91 304.3 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 EWM22357.1 - 4.7e-12 46.3 0.1 8.2e-12 45.6 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EspF PF04806.12 EWM22357.1 - 0.13 12.7 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 EspF protein repeat ECH_2 PF16113.5 EWM22359.1 - 2.1e-71 241.1 0.0 9.9e-61 206.1 0.0 2.2 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase DUF393 PF04134.12 EWM22359.1 - 3.4e-22 79.9 0.0 6.4e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF393 ECH_1 PF00378.20 EWM22359.1 - 1.8e-20 73.3 0.3 5.4e-20 71.8 0.1 1.9 2 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Flot PF15975.5 EWM22359.1 - 0.075 13.2 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Flotillin G-patch PF01585.23 EWM22360.1 - 0.0003 20.6 8.0 0.00067 19.5 7.3 1.9 1 1 1 2 2 2 1 G-patch domain zf-C2H2_jaz PF12171.8 EWM22360.1 - 0.0028 17.9 0.2 0.0053 17.0 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EWM22360.1 - 0.014 15.7 0.0 0.036 14.5 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type DUF3449 PF11931.8 EWM22360.1 - 0.026 14.3 1.3 0.045 13.6 1.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3449) G-patch_2 PF12656.7 EWM22360.1 - 3.7 7.7 5.1 1.3 9.1 1.9 1.9 2 0 0 2 2 2 0 G-patch domain PDCD2_C PF04194.13 EWM22361.1 - 3e-43 147.9 0.0 2.9e-40 138.2 0.0 2.3 2 0 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain zf-MYND PF01753.18 EWM22361.1 - 9e-09 35.3 8.5 9e-09 35.3 8.5 2.9 5 0 0 5 5 5 1 MYND finger AOX PF01786.17 EWM22362.1 - 2.7e-29 102.3 3.7 3.6e-29 101.9 3.7 1.1 1 0 0 1 1 1 1 Alternative oxidase Peptidase_M16_C PF05193.21 EWM22363.1 - 8.4e-32 110.7 0.0 1.1e-31 110.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EWM22363.1 - 0.0032 17.5 0.0 0.0057 16.6 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) FMO-like PF00743.19 EWM22364.1 - 1.2e-48 165.9 0.0 7.1e-20 70.9 0.0 3.7 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EWM22364.1 - 3.5e-13 49.5 0.0 3.8e-07 29.7 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EWM22364.1 - 5e-08 32.5 0.1 0.0022 17.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EWM22364.1 - 7.1e-07 29.4 0.0 2e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EWM22364.1 - 0.00084 18.7 0.2 0.0016 17.8 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 EWM22364.1 - 0.0028 17.6 0.0 0.05 13.6 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 EWM22364.1 - 0.003 16.3 0.3 0.0045 15.8 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 EWM22364.1 - 0.0033 16.7 0.0 0.011 15.0 0.0 1.7 2 0 0 2 2 2 1 Thi4 family 2-Hacid_dh_C PF02826.19 EWM22364.1 - 0.011 15.0 0.0 4.4 6.6 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 EWM22364.1 - 0.018 14.2 0.3 0.026 13.6 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 EWM22364.1 - 0.019 15.5 0.6 8.2 7.1 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 EWM22364.1 - 0.094 12.2 0.1 0.44 10.0 0.1 2.0 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus K_oxygenase PF13434.6 EWM22364.1 - 0.13 11.3 0.3 0.9 8.6 0.0 2.3 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 EWM22364.1 - 0.15 11.4 0.3 0.34 10.2 0.0 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EWM22364.1 - 0.16 11.9 2.1 1.3 8.9 0.4 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain LEA_2 PF03168.13 EWM22365.1 - 0.012 16.1 0.0 0.019 15.5 0.0 1.2 1 0 0 1 1 1 0 Late embryogenesis abundant protein PSI PF01437.25 EWM22365.1 - 0.052 14.1 14.7 0.13 12.8 14.7 1.7 1 1 0 1 1 1 0 Plexin repeat SPT_ssu-like PF11779.8 EWM22365.1 - 0.49 10.0 3.9 7.2 6.3 0.3 2.5 2 0 0 2 2 2 0 Small subunit of serine palmitoyltransferase-like KASH PF10541.9 EWM22365.1 - 6.2 7.2 6.7 5.1 7.4 0.5 2.6 2 0 0 2 2 2 0 Nuclear envelope localisation domain DAO PF01266.24 EWM22366.1 - 5.4e-07 29.5 0.0 0.0064 16.1 0.0 3.3 4 0 0 4 4 4 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EWM22366.1 - 3.5e-05 22.8 0.1 0.0012 17.8 0.0 2.4 2 1 0 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.12 EWM22366.1 - 0.00013 21.2 0.1 0.00024 20.3 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 EWM22366.1 - 0.0014 17.9 0.0 0.0045 16.3 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EWM22366.1 - 0.0086 15.4 0.0 0.026 13.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EWM22366.1 - 0.2 10.9 0.6 0.61 9.4 0.6 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 EWM22366.1 - 0.2 11.5 0.0 0.34 10.8 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 EWM22366.1 - 0.22 12.1 0.2 0.67 10.6 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GST_N_2 PF13409.6 EWM22367.1 - 3.7e-12 46.4 0.0 8.3e-12 45.2 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EWM22367.1 - 1.5e-10 41.4 0.0 2.7e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EWM22367.1 - 6.4e-08 32.5 0.1 1.3e-07 31.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EWM22367.1 - 1.8e-06 28.2 0.0 3.3e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EWM22367.1 - 0.0071 16.5 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EWM22367.1 - 0.051 14.2 0.0 0.086 13.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EWM22367.1 - 0.093 12.9 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain IPP-2 PF04979.14 EWM22368.1 - 3.7e-13 50.3 21.2 8.3e-12 46.0 20.2 2.4 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) Pro_isomerase PF00160.21 EWM22369.1 - 8.2e-47 159.4 1.3 9.7e-47 159.2 0.0 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SYF2 PF08231.12 EWM22369.1 - 4.4e-25 88.9 3.4 4.4e-25 88.9 3.4 2.3 2 0 0 2 2 2 1 SYF2 splicing factor SRP_SPB PF02978.19 EWM22370.1 - 1.7e-08 35.0 0.3 2.9e-07 31.0 0.0 2.3 1 1 1 2 2 2 1 Signal peptide binding domain zf-CDGSH PF09360.10 EWM22371.1 - 6e-12 45.6 0.1 1.3e-11 44.5 0.1 1.6 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type Pro_isomerase PF00160.21 EWM22373.1 - 2.6e-53 180.5 0.1 5.7e-53 179.4 0.1 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 EWM22373.1 - 3.5e-20 72.0 0.0 0.00048 20.9 0.0 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EWM22373.1 - 5.6e-06 25.5 0.1 0.29 10.0 0.0 3.6 3 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 EWM22373.1 - 8e-05 22.9 0.0 2.4 8.5 0.0 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain OSCP PF00213.18 EWM22374.1 - 1.1e-24 87.5 0.2 1.4e-24 87.2 0.2 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Uteroglobin PF01099.17 EWM22374.1 - 0.071 13.5 0.2 0.2 12.0 0.2 1.7 2 0 0 2 2 2 0 Uteroglobin family DUF2470 PF10615.9 EWM22375.1 - 5.5e-15 55.7 0.0 1.1e-14 54.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Suc_Fer-like PF06999.12 EWM22375.1 - 1.7e-09 37.9 1.6 2e-09 37.6 0.0 1.8 2 0 0 2 2 2 1 Sucrase/ferredoxin-like F-box PF00646.33 EWM22376.1 - 0.00036 20.3 0.1 0.0012 18.7 0.1 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EWM22376.1 - 0.00041 20.2 0.0 0.0009 19.1 0.0 1.5 1 0 0 1 1 1 1 F-box-like Mito_carr PF00153.27 EWM22377.1 - 6e-50 167.1 0.0 1.7e-19 69.5 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.25 EWM22378.1 - 6.3e-78 261.8 0.0 7.8e-78 261.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM22378.1 - 8.4e-35 120.3 0.0 1.1e-34 119.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EWM22378.1 - 5.1e-06 26.6 0.1 0.022 14.7 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EWM22378.1 - 0.0013 18.1 0.0 0.0038 16.6 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EWM22378.1 - 0.0068 15.2 0.0 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 EWM22378.1 - 0.095 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.11 EWM22378.1 - 0.12 11.3 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TCR PF03638.15 EWM22379.1 - 1e-23 83.4 48.7 7.2e-12 45.4 18.8 2.2 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain KAsynt_C_assoc PF16197.5 EWM22379.1 - 9.8 6.7 6.3 56 4.2 5.0 2.6 2 0 0 2 2 2 0 Ketoacyl-synthetase C-terminal extension CCT PF06203.14 EWM22380.1 - 2e-17 62.9 12.4 3.6e-17 62.1 12.4 1.4 1 0 0 1 1 1 1 CCT motif NmrA PF05368.13 EWM22381.1 - 3.4e-26 92.2 0.0 4.9e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EWM22381.1 - 9.7e-08 32.1 0.0 2.1e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EWM22381.1 - 0.014 14.9 0.0 0.052 13.0 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EWM22381.1 - 0.11 11.4 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF692 PF05114.13 EWM22381.1 - 0.18 11.0 0.1 13 4.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF692) AI-2E_transport PF01594.16 EWM22382.1 - 1.4e-26 93.5 15.1 1.4e-26 93.5 15.1 2.1 2 1 0 2 2 2 1 AI-2E family transporter Sec63 PF02889.16 EWM22383.1 - 6.4e-159 526.9 0.0 8e-84 280.8 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EWM22383.1 - 9e-38 129.8 0.0 2.1e-25 89.5 0.1 3.5 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 EWM22383.1 - 1.5e-27 96.0 1.5 3.1e-26 91.7 0.3 3.1 3 0 0 3 3 3 1 N-terminal helicase PWI domain ResIII PF04851.15 EWM22383.1 - 4.1e-15 56.2 0.0 4.8e-11 43.0 0.0 3.3 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EWM22383.1 - 2.1e-09 37.7 0.1 2.4e-08 34.3 0.0 2.8 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EWM22383.1 - 0.0037 17.5 0.2 2.2 8.5 0.2 3.5 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EWM22383.1 - 0.031 14.0 0.0 4.5 7.0 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_11 PF13086.6 EWM22383.1 - 0.047 13.5 0.0 9 6.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain RhoGAP PF00620.27 EWM22384.1 - 2.6e-30 105.3 0.0 4.3e-30 104.5 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.17 EWM22384.1 - 6.8e-10 39.4 0.1 2.8e-09 37.4 0.0 2.1 2 0 0 2 2 2 1 MyTH4 domain PH PF00169.29 EWM22384.1 - 0.0046 17.4 0.0 0.013 16.0 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_12 PF16457.5 EWM22384.1 - 0.16 12.5 0.0 0.44 11.1 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain Myb_DNA-binding PF00249.31 EWM22385.1 - 1.8e-31 108.0 5.6 3e-12 46.5 0.0 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EWM22385.1 - 5.1e-26 90.7 3.4 3.4e-12 46.4 0.0 3.3 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EWM22385.1 - 0.0068 16.3 0.0 0.18 11.7 0.0 2.7 2 1 1 3 3 3 1 Myb DNA-binding like Rap1_C PF11626.8 EWM22385.1 - 0.023 14.8 0.2 0.67 10.1 0.2 2.8 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Pkinase PF00069.25 EWM22386.1 - 1.6e-63 214.5 0.0 2.4e-63 214.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM22386.1 - 3.2e-31 108.6 0.0 5e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EWM22386.1 - 5.8e-07 30.1 0.7 1.4e-06 28.8 0.7 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.23 EWM22386.1 - 5.7e-05 23.2 0.1 0.00095 19.1 0.2 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EWM22386.1 - 0.00031 20.2 0.0 0.00059 19.2 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EWM22386.1 - 0.0035 16.2 0.0 0.0058 15.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EWM22386.1 - 0.03 13.7 0.1 0.068 12.5 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EWM22386.1 - 0.035 13.7 0.0 0.33 10.6 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EWM22386.1 - 0.046 13.3 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family RRP7 PF12923.7 EWM22386.1 - 0.21 11.8 0.0 0.48 10.6 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain DENN PF02141.21 EWM22387.1 - 1.1e-44 152.6 2.7 2e-44 151.8 2.7 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 EWM22387.1 - 3.8e-14 53.2 1.3 3.8e-14 53.2 1.3 2.0 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.19 EWM22387.1 - 0.00028 20.8 0.0 0.00055 19.9 0.0 1.5 1 0 0 1 1 1 1 dDENN domain DUF2464 PF10240.9 EWM22387.1 - 0.0019 17.8 0.0 0.0054 16.3 0.0 1.9 1 0 0 1 1 1 1 Multivesicular body subunit 12 Pep1_7 PF17232.2 EWM22387.1 - 1.7 9.2 4.0 5 7.6 4.0 1.9 1 0 0 1 1 1 0 Elicitor peptide 1-7 TraC PF07820.12 EWM22388.1 - 1.5 9.2 0.0 1.5 9.2 0.0 2.8 3 0 0 3 3 3 0 TraC-like protein PIF1 PF05970.14 EWM22390.1 - 1.3e-37 129.8 0.2 7e-28 97.8 0.0 3.3 3 1 0 3 3 3 2 PIF1-like helicase AAA_30 PF13604.6 EWM22390.1 - 6.5e-19 68.4 0.0 1.1e-14 54.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EWM22390.1 - 1.6e-09 38.3 0.0 3.3e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EWM22390.1 - 0.0013 18.7 0.2 0.012 15.6 0.1 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EWM22390.1 - 0.0026 18.2 0.1 0.0077 16.6 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EWM22390.1 - 0.0038 17.5 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EWM22390.1 - 0.011 15.5 0.1 0.33 10.6 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain T2SSE PF00437.20 EWM22390.1 - 0.08 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF1772 PF08592.11 EWM22391.1 - 0.05 13.9 0.6 1.6 9.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) NOA36 PF06524.12 EWM22393.1 - 0.017 14.5 3.9 0.018 14.4 3.9 1.0 1 0 0 1 1 1 0 NOA36 protein Pro_isomerase PF00160.21 EWM22394.1 - 3.4e-46 157.4 0.1 3.9e-46 157.2 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Amidohydro_1 PF01979.20 EWM22395.1 - 1.2e-20 74.1 0.0 1.7e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 EWM22395.1 - 0.00036 20.4 0.1 0.00053 19.9 0.1 1.3 1 0 0 1 1 1 1 Amidohydrolase SNF2_N PF00176.23 EWM22396.1 - 7.5e-49 166.3 0.0 1.2e-48 165.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EWM22396.1 - 1.5e-13 51.1 0.0 3.1e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EWM22396.1 - 1.4e-08 34.9 0.0 9.5e-08 32.2 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-RanBP PF00641.18 EWM22396.1 - 2.5e-06 26.7 4.7 6.1e-06 25.4 4.7 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others HDA2-3 PF11496.8 EWM22396.1 - 0.00081 18.6 0.9 0.0018 17.5 0.0 2.0 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Ephrin_rec_like PF07699.13 EWM22396.1 - 4.3 7.2 6.7 8.5 6.2 2.6 2.5 2 0 0 2 2 2 0 Putative ephrin-receptor like Rad1 PF02144.16 EWM22397.1 - 0.00019 20.6 0.0 0.00025 20.2 0.0 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Peptidase_M15_2 PF05951.13 EWM22397.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) IspD PF01128.19 EWM22399.1 - 8.1e-57 192.5 0.0 9.6e-57 192.3 0.0 1.0 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transf_3 PF12804.7 EWM22399.1 - 6e-10 39.7 0.0 7.5e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 EWM22399.1 - 0.021 14.4 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyl transferase PRP3 PF08572.10 EWM22400.1 - 0.012 15.4 0.3 0.013 15.2 0.3 1.1 1 0 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) DUF3381 PF11861.8 EWM22400.1 - 0.049 13.4 1.1 0.063 13.1 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Methyltransf_16 PF10294.9 EWM22401.1 - 1.6e-24 86.6 0.0 2.2e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 EWM22401.1 - 2.3e-06 27.3 0.0 3.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EWM22401.1 - 0.00015 21.3 0.0 0.00021 20.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 EWM22401.1 - 0.00026 21.7 0.0 0.00045 20.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM22401.1 - 0.0011 18.8 0.1 0.0019 18.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM22401.1 - 0.0011 19.6 0.1 0.0027 18.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EWM22401.1 - 0.0046 16.8 0.0 0.0068 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Rep_fac-A_C PF08646.10 EWM22402.1 - 5.7e-43 146.1 2.4 7.8e-43 145.7 0.6 2.0 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 EWM22402.1 - 1.9e-32 111.1 0.0 2.1e-31 107.7 0.0 2.2 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 EWM22402.1 - 7.2e-27 93.4 0.0 1.4e-26 92.5 0.0 1.5 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 EWM22402.1 - 1.8e-12 47.0 0.1 1.6e-07 31.2 0.0 3.2 3 1 0 3 3 3 2 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 EWM22402.1 - 0.041 13.6 0.0 1.1 8.9 0.1 2.6 3 0 0 3 3 3 0 Cell division control protein 24, OB domain 3 Flg_bbr_C PF06429.13 EWM22402.1 - 0.073 13.2 0.6 0.16 12.2 0.1 1.9 2 0 0 2 2 2 0 Flagellar basal body rod FlgEFG protein C-terminal WD40 PF00400.32 EWM22403.1 - 3.7e-06 27.6 5.3 0.13 13.2 0.8 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat Tub PF01167.18 EWM22404.1 - 6.6e-14 52.2 0.0 7.3e-12 45.6 0.0 2.2 2 0 0 2 2 2 2 Tub family DUF3527 PF12043.8 EWM22404.1 - 0.045 13.3 0.0 0.073 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) FF PF01846.19 EWM22405.1 - 3.6e-29 100.7 12.2 3.9e-10 39.7 0.8 5.6 6 0 0 6 6 6 4 FF domain WW PF00397.26 EWM22405.1 - 1.4e-07 31.5 13.2 2.1e-05 24.5 1.5 2.8 2 1 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 EWM22405.1 - 3.2e-06 27.7 13.9 0.0016 19.1 0.0 4.6 3 1 1 4 4 4 3 p190-A and -B Rho GAPs FF domain FF PF01846.19 EWM22406.1 - 3.9e-29 100.6 12.2 4.1e-10 39.7 0.8 5.6 6 0 0 6 6 6 4 FF domain WW PF00397.26 EWM22406.1 - 1.5e-07 31.4 13.2 2.2e-05 24.5 1.5 2.8 2 1 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 EWM22406.1 - 3.5e-06 27.6 13.9 0.0016 19.1 0.0 4.6 3 1 1 4 4 4 3 p190-A and -B Rho GAPs FF domain TLC PF03219.14 EWM22407.1 - 3.7e-140 467.9 14.5 4.8e-140 467.6 14.5 1.1 1 0 0 1 1 1 1 TLC ATP/ADP transporter Ldr_toxin PF13940.6 EWM22407.1 - 0.12 12.5 4.3 0.63 10.1 0.2 3.2 3 0 0 3 3 3 0 Toxin Ldr, type I toxin-antitoxin system DUF805 PF05656.14 EWM22407.1 - 0.51 10.8 0.1 0.51 10.8 0.1 4.1 4 1 0 4 4 4 0 Protein of unknown function (DUF805) Proteasome PF00227.26 EWM22408.1 - 4e-55 186.2 0.7 5.1e-55 185.9 0.7 1.1 1 0 0 1 1 1 1 Proteasome subunit TMEM234 PF10639.9 EWM22408.1 - 1.7e-20 73.2 0.2 3.2e-20 72.3 0.2 1.4 1 0 0 1 1 1 1 Putative transmembrane family 234 Proteasome_A_N PF10584.9 EWM22408.1 - 3.8e-13 48.8 0.0 7.9e-13 47.8 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature EamA PF00892.20 EWM22408.1 - 0.0016 18.6 0.8 0.0024 18.0 0.8 1.2 1 0 0 1 1 1 1 EamA-like transporter family Asp_Arg_Hydrox PF05118.15 EWM22409.1 - 1.3e-27 96.6 0.0 1.9e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase ANAPC4_WD40 PF12894.7 EWM22410.1 - 1.3e-16 60.7 0.0 0.0084 16.4 0.0 7.5 5 2 2 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EWM22410.1 - 3.5e-11 43.5 8.8 0.011 16.5 0.0 9.7 10 0 0 10 10 10 2 WD domain, G-beta repeat Nbas_N PF15492.6 EWM22410.1 - 0.00032 20.1 0.1 0.013 14.9 0.0 3.6 5 0 0 5 5 5 1 Neuroblastoma-amplified sequence, N terminal PQQ PF01011.21 EWM22410.1 - 0.0015 18.4 0.0 1.6 8.8 0.0 4.9 6 0 0 6 6 6 1 PQQ enzyme repeat Ge1_WD40 PF16529.5 EWM22410.1 - 0.003 16.6 0.0 1.4 7.8 0.0 3.2 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 EWM22410.1 - 0.0048 17.4 9.4 35 5.1 0.1 7.8 9 0 0 9 9 9 0 PQQ-like domain PQQ_2 PF13360.6 EWM22410.1 - 0.0076 15.9 2.2 0.089 12.4 0.1 3.5 3 2 1 4 4 4 1 PQQ-like domain Frtz PF11768.8 EWM22410.1 - 0.019 13.3 0.0 2.9 6.1 0.0 2.7 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF4033 PF13225.6 EWM22410.1 - 0.086 12.9 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4033) PD40 PF07676.12 EWM22410.1 - 0.18 11.8 0.2 1.6 8.8 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat ACPS PF01648.20 EWM22411.1 - 1.1e-12 48.1 0.0 3.8e-12 46.3 0.0 1.9 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 EWM22411.1 - 5.4e-09 36.1 0.0 1.3e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase N-terminal domain tRNA-synt_2b PF00587.25 EWM22412.1 - 8.4e-34 117.1 0.0 1.3e-33 116.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS PF00458.20 EWM22412.1 - 7e-31 106.2 17.4 3.8e-16 59.0 2.2 3.5 4 0 0 4 4 4 2 WHEP-TRS domain Seryl_tRNA_N PF02403.22 EWM22412.1 - 0.053 13.7 0.7 0.053 13.7 0.7 3.2 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain STI1 PF17830.1 EWM22413.1 - 4.3e-09 36.2 1.9 9.5e-09 35.1 1.9 1.6 1 0 0 1 1 1 1 STI1 domain SR-25 PF10500.9 EWM22413.1 - 3e-05 23.8 15.2 4.7e-05 23.1 15.2 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 EWM22413.1 - 0.0065 15.1 6.9 0.0085 14.7 6.9 1.2 1 0 0 1 1 1 1 Macoilin family SAP PF02037.27 EWM22413.1 - 0.031 14.1 0.6 3.4 7.5 0.0 2.4 2 0 0 2 2 2 0 SAP domain AF-4 PF05110.13 EWM22413.1 - 0.042 12.0 14.8 0.05 11.7 14.8 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Bul1_N PF04425.12 EWM22413.1 - 0.048 12.4 1.6 0.07 11.9 1.6 1.1 1 0 0 1 1 1 0 Bul1 N terminus DUF908 PF06012.12 EWM22413.1 - 0.061 12.7 3.6 0.083 12.3 3.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Herpes_pp85 PF04637.12 EWM22413.1 - 0.1 11.0 5.0 0.15 10.4 5.0 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Tmemb_cc2 PF10267.9 EWM22413.1 - 0.11 11.7 4.6 0.16 11.1 4.6 1.4 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Polyoma_lg_T_C PF06431.11 EWM22413.1 - 0.13 11.2 0.7 0.18 10.7 0.7 1.1 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus CCDC106 PF15794.5 EWM22413.1 - 0.14 11.9 6.7 0.21 11.3 6.7 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 RAP1 PF07218.11 EWM22413.1 - 0.15 10.3 8.1 0.19 10.0 8.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Apt1 PF10351.9 EWM22413.1 - 0.46 9.3 8.2 0.61 8.9 8.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PI3K_1B_p101 PF10486.9 EWM22413.1 - 0.61 7.8 7.0 0.72 7.6 7.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CAML PF14963.6 EWM22413.1 - 0.65 10.1 4.1 0.95 9.5 4.1 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand EBP50_C PF09007.11 EWM22413.1 - 1.1 10.2 9.6 2.3 9.2 9.6 1.5 1 0 0 1 1 1 0 EBP50, C-terminal DUF508 PF04370.12 EWM22413.1 - 1.5 8.6 10.9 2.6 7.8 10.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF508) GEMIN8 PF15348.6 EWM22413.1 - 2.2 8.5 5.0 3.6 7.8 5.0 1.3 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 SSP160 PF06933.11 EWM22413.1 - 7 4.7 13.5 9.3 4.3 13.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 JAKMIP_CC3 PF16034.5 EWM22413.1 - 8 6.4 10.0 1.4 8.9 0.2 2.3 1 1 0 2 2 2 0 JAKMIP CC3 domain DUF755 PF05501.11 EWM22413.1 - 8.2 6.7 22.0 18 5.6 22.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF755) RNA_polI_A34 PF08208.11 EWM22414.1 - 1.9e-16 60.8 0.7 3.7e-16 59.8 0.7 1.4 1 1 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 Meth_synt_1 PF08267.12 EWM22415.1 - 5e-79 266.1 0.0 7e-79 265.6 0.0 1.2 1 0 0 1 1 1 1 Cobalamin-independent synthase, N-terminal domain Meth_synt_2 PF01717.18 EWM22415.1 - 3.4e-66 223.7 0.1 2e-61 208.0 0.0 3.1 3 1 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_2 PF01717.18 EWM22416.1 - 2.2e-141 470.9 0.0 8.8e-137 455.7 0.0 3.0 3 1 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EWM22416.1 - 1.5e-83 280.9 0.0 9.3e-79 265.2 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain PPR_2 PF13041.6 EWM22417.1 - 8.4e-20 70.7 0.0 6.7e-06 26.2 0.0 5.1 3 2 3 6 6 6 5 PPR repeat family PPR_3 PF13812.6 EWM22417.1 - 3.2e-17 62.4 0.0 0.00041 20.4 0.0 5.0 4 1 1 5 5 5 3 Pentatricopeptide repeat domain PPR PF01535.20 EWM22417.1 - 6.9e-16 57.3 11.8 0.0042 17.2 0.1 6.3 6 0 0 6 6 6 4 PPR repeat PPR_long PF17177.4 EWM22417.1 - 3.3e-09 36.4 0.0 3.5e-05 23.3 0.0 2.2 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EWM22417.1 - 6.3e-08 32.2 0.0 0.43 10.3 0.0 5.2 5 0 0 5 5 5 3 PPR repeat HRM PF02793.22 EWM22417.1 - 0.12 12.7 3.8 21 5.5 0.1 3.6 2 1 1 3 3 3 0 Hormone receptor domain Radical_SAM PF04055.21 EWM22418.1 - 5.2e-30 105.0 0.1 1.6e-29 103.4 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily UPF0004 PF00919.20 EWM22418.1 - 1.4e-27 95.5 0.2 4.2e-27 94.1 0.2 1.9 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Rotamase_3 PF13616.6 EWM22418.1 - 6.8e-10 39.5 0.0 1.6e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 PPIC-type PPIASE domain TRAM PF01938.20 EWM22418.1 - 1.3e-07 31.5 0.2 2.7e-07 30.5 0.2 1.6 1 0 0 1 1 1 1 TRAM domain Rotamase PF00639.21 EWM22418.1 - 3.3e-06 28.0 0.0 1.5e-05 25.9 0.0 2.2 2 0 0 2 2 2 1 PPIC-type PPIASE domain Fer4_12 PF13353.6 EWM22418.1 - 0.13 12.6 0.0 0.41 10.9 0.0 1.8 1 0 0 1 1 1 0 4Fe-4S single cluster domain PX PF00787.24 EWM22419.1 - 1.8e-10 40.8 0.0 3.2e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 PX domain FAIM1 PF06905.13 EWM22419.1 - 0.0006 19.6 0.0 0.00099 18.9 0.0 1.2 1 0 0 1 1 1 1 Fas apoptotic inhibitory molecule (FAIM1) PDZ PF00595.24 EWM22419.1 - 0.01 16.2 0.1 0.023 15.0 0.1 1.5 1 0 0 1 1 1 0 PDZ domain PDZ_6 PF17820.1 EWM22419.1 - 0.082 12.8 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 PDZ domain Methyltransf_11 PF08241.12 EWM22420.1 - 1.2e-24 86.8 0.0 2.2e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM22420.1 - 1.6e-23 83.2 0.0 3.7e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM22420.1 - 6.6e-23 81.2 0.0 1.1e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EWM22420.1 - 1.6e-17 63.8 0.0 2.6e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EWM22420.1 - 2.5e-15 57.0 0.0 5.3e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EWM22420.1 - 2.9e-14 53.0 0.0 4.9e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EWM22420.1 - 1.4e-12 47.5 0.0 2e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_29 PF03141.16 EWM22420.1 - 1.8e-07 30.1 0.0 2.5e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.19 EWM22420.1 - 1.9e-07 31.1 0.0 2.8e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_PK PF05891.12 EWM22420.1 - 3.4e-05 23.5 0.0 5.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase ADH_zinc_N PF00107.26 EWM22420.1 - 8e-05 22.6 0.0 0.00017 21.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MTS PF05175.14 EWM22420.1 - 0.00018 21.1 0.0 0.00035 20.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 EWM22420.1 - 0.00018 21.2 0.0 0.0003 20.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) TehB PF03848.14 EWM22420.1 - 0.00031 20.2 0.0 0.007 15.8 0.0 2.3 1 1 0 2 2 2 1 Tellurite resistance protein TehB MetW PF07021.12 EWM22420.1 - 0.00035 20.2 0.0 0.00065 19.4 0.0 1.4 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW FtsJ PF01728.19 EWM22420.1 - 0.00038 20.6 0.0 0.002 18.3 0.0 1.9 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 EWM22420.1 - 0.0007 19.1 0.0 0.016 14.7 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase PrmA PF06325.13 EWM22420.1 - 0.0037 16.7 0.0 0.011 15.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 EWM22420.1 - 0.0039 17.2 0.0 0.006 16.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EWM22420.1 - 0.013 15.4 0.0 0.033 14.0 0.0 1.6 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltr_RsmB-F PF01189.17 EWM22420.1 - 0.034 13.8 0.0 0.21 11.2 0.0 1.9 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F Rsm22 PF09243.10 EWM22420.1 - 0.048 12.9 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 NAS PF03059.16 EWM22420.1 - 0.049 13.0 0.0 0.064 12.6 0.0 1.1 1 0 0 1 1 1 0 Nicotianamine synthase protein Shikimate_DH PF01488.20 EWM22420.1 - 0.077 13.1 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Methyltransf_24 PF13578.6 EWM22420.1 - 0.077 14.0 0.0 0.15 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 EWM22420.1 - 0.086 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Hemerythrin PF01814.23 EWM22421.1 - 1.5e-07 32.1 0.1 0.0016 19.0 0.0 2.9 3 0 0 3 3 3 2 Hemerythrin HHE cation binding domain Sigma70_r4 PF04545.16 EWM22422.1 - 6.6e-07 28.8 0.7 2e-06 27.2 0.2 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r2 PF04542.14 EWM22422.1 - 7.3e-06 25.7 0.1 2.3e-05 24.1 0.1 1.9 1 0 0 1 1 1 1 Sigma-70 region 2 DprA_WH PF17782.1 EWM22422.1 - 0.0043 17.1 0.8 0.021 14.9 0.1 2.4 2 0 0 2 2 2 1 DprA winged helix domain HTH_24 PF13412.6 EWM22422.1 - 0.023 14.3 0.1 1.6 8.3 0.0 2.6 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding GerE PF00196.19 EWM22422.1 - 0.1 12.2 0.0 0.56 9.8 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.12 EWM22422.1 - 0.42 10.3 3.6 1 9.1 1.7 2.6 2 1 0 2 2 2 0 Sigma-70, region 4 Cupin_8 PF13621.6 EWM22423.1 - 1.6e-09 37.9 0.0 2.3e-09 37.3 0.0 1.4 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EWM22423.1 - 1.5e-07 31.2 0.1 0.0001 21.9 0.0 2.7 2 1 0 2 2 2 2 Cupin superfamily protein Cupin_2 PF07883.11 EWM22423.1 - 0.035 13.8 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 Cupin domain Pkinase PF00069.25 EWM22424.1 - 8.5e-68 228.6 0.0 1.2e-67 228.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM22424.1 - 2.3e-47 161.4 0.0 3.3e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.8 EWM22424.1 - 4.3e-15 55.8 0.2 8e-15 54.9 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase_fungal PF17667.1 EWM22424.1 - 0.00017 20.5 0.0 0.00035 19.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EWM22424.1 - 0.0046 16.9 0.3 0.0046 16.9 0.3 4.3 3 1 1 4 4 4 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EWM22424.1 - 0.04 13.2 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.11 EWM22424.1 - 0.055 12.4 0.1 2.2 7.1 0.2 2.3 2 1 0 2 2 2 0 Poxvirus serine/threonine protein kinase PHF5 PF03660.14 EWM22425.1 - 1.5e-50 169.8 11.9 1.6e-50 169.6 11.9 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 EWM22425.1 - 0.044 11.6 7.5 0.044 11.7 7.5 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 EWM22425.1 - 2.1 8.4 14.5 2.5 8.2 2.0 2.8 1 1 1 2 2 2 0 Double zinc ribbon fn3 PF00041.21 EWM22427.1 - 4.2e-08 33.4 0.0 5.2e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Fibronectin type III domain Interfer-bind PF09294.10 EWM22427.1 - 0.04 14.2 0.0 0.052 13.9 0.0 1.2 1 0 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III DAO PF01266.24 EWM22428.1 - 5.3e-56 190.7 0.8 6.1e-56 190.5 0.8 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EWM22428.1 - 1.3e-05 25.4 0.2 2.6e-05 24.4 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EWM22428.1 - 0.00053 20.5 0.2 0.0018 18.8 0.3 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EWM22428.1 - 0.011 15.0 0.4 0.011 15.0 0.4 1.5 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 EWM22428.1 - 0.011 14.8 0.7 0.031 13.3 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EWM22428.1 - 0.012 14.8 0.6 0.059 12.6 0.3 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EWM22428.1 - 0.02 15.1 0.0 0.044 14.1 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.17 EWM22428.1 - 0.021 14.1 0.2 0.05 12.8 0.2 1.6 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 EWM22428.1 - 0.071 11.8 0.4 0.11 11.2 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 EWM22428.1 - 0.078 12.0 0.2 0.14 11.2 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 EWM22428.1 - 0.11 11.9 2.8 2.8 7.2 2.8 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase MDM10 PF12519.8 EWM22428.1 - 0.17 10.8 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Beta-lactamase PF00144.24 EWM22429.1 - 1.1e-55 189.2 0.1 1.8e-55 188.5 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase IF-2B PF01008.17 EWM22430.1 - 2.6e-73 246.7 0.0 3.2e-73 246.4 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Keratin_2_tail PF16210.5 EWM22430.1 - 8.2 6.7 24.6 14 6.0 24.6 1.3 1 0 0 1 1 1 0 Keratin type II cytoskeletal 1 tail His_Phos_1 PF00300.22 EWM22431.1 - 5.2e-36 124.2 0.0 6.4e-33 114.1 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) F-box-like PF12937.7 EWM22432.1 - 0.00064 19.6 0.0 0.0017 18.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like PQQ_3 PF13570.6 EWM22432.1 - 0.14 12.6 5.7 1.1 9.9 0.6 3.5 4 1 0 4 4 4 0 PQQ-like domain F-box PF00646.33 EWM22432.1 - 0.88 9.5 0.0 0.88 9.5 0.0 2.8 3 1 0 3 3 3 0 F-box domain Lipase_3 PF01764.25 EWM22433.1 - 1.4e-13 50.9 0.0 2.4e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EWM22433.1 - 0.0088 16.7 0.4 0.021 15.4 0.4 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EWM22433.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Asp PF00026.23 EWM22434.1 - 2.9e-82 276.6 0.0 3.5e-82 276.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EWM22434.1 - 1.2e-11 45.2 0.6 4.2e-07 30.4 0.0 2.2 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EWM22434.1 - 0.001 18.9 0.0 0.0047 16.7 0.0 1.9 1 1 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 EWM22434.1 - 0.12 13.0 0.0 1.8 9.3 0.0 2.5 2 0 0 2 2 2 0 Aspartyl protease UCH PF00443.29 EWM22435.1 - 9e-41 140.1 0.0 1.5e-40 139.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EWM22435.1 - 6.4e-18 65.4 0.0 2.8e-17 63.3 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L26 PF16906.5 EWM22436.1 - 2.8e-38 130.2 5.9 3.7e-38 129.9 5.9 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 EWM22436.1 - 2.8e-05 23.9 3.3 8.4e-05 22.4 3.3 1.8 1 0 0 1 1 1 1 KOW motif DUF3485 PF11984.8 EWM22436.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3485) VEG PF06257.11 EWM22436.1 - 0.2 11.7 2.6 0.51 10.4 0.2 2.3 1 1 1 2 2 2 0 Biofilm formation stimulator VEG RRM_1 PF00076.22 EWM22437.1 - 1.8e-54 181.5 0.7 2.6e-15 56.0 0.0 6.0 6 0 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EWM22437.1 - 3e-05 24.0 0.6 0.0025 17.8 0.0 3.8 3 1 0 3 3 3 1 Limkain b1 RRM_Rrp7 PF17799.1 EWM22437.1 - 0.0021 17.9 0.1 0.46 10.3 0.0 3.4 4 0 0 4 4 4 1 Rrp7 RRM-like N-terminal domain RRM_occluded PF16842.5 EWM22437.1 - 0.013 15.4 0.6 0.28 11.1 0.1 2.9 3 0 0 3 3 3 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EWM22437.1 - 0.035 14.1 0.0 0.72 9.9 0.0 2.8 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif PPTA PF01239.22 EWM22438.1 - 7.2e-39 130.4 14.8 7e-12 44.7 0.2 5.6 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DNApol3-delta_C PF09115.10 EWM22438.1 - 0.055 14.0 1.9 0.15 12.6 0.3 2.3 2 0 0 2 2 2 0 DNA polymerase III, delta subunit, C terminal Peptidase_M16_C PF05193.21 EWM22439.1 - 1.7e-31 109.7 0.0 2.5e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EWM22439.1 - 3.5e-23 82.2 0.0 6.5e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Str_synth PF03088.16 EWM22440.1 - 6.2e-08 32.6 0.0 1.9e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 Strictosidine synthase AAA PF00004.29 EWM22441.1 - 1.2e-39 135.7 0.0 2.8e-39 134.6 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.18 EWM22441.1 - 3.6e-14 52.6 3.5 9.3e-14 51.3 3.5 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 EWM22441.1 - 3.2e-06 26.8 0.0 1.5e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 AAA+ lid domain RuvB_N PF05496.12 EWM22441.1 - 6.3e-06 26.0 0.0 1.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EWM22441.1 - 4.3e-05 23.8 0.7 0.008 16.5 0.7 2.6 1 1 0 1 1 1 1 AAA domain Vps4_C PF09336.10 EWM22441.1 - 7.1e-05 22.7 0.0 0.00017 21.5 0.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain TIP49 PF06068.13 EWM22441.1 - 0.0001 21.6 0.0 0.00017 20.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_25 PF13481.6 EWM22441.1 - 0.00013 21.6 0.1 0.1 12.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EWM22441.1 - 0.00062 19.8 0.1 0.0025 17.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EWM22441.1 - 0.00088 19.8 0.0 0.0017 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EWM22441.1 - 0.0011 19.1 0.0 0.0023 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 EWM22441.1 - 0.0012 18.6 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 EWM22441.1 - 0.0016 18.8 6.9 0.0079 16.6 0.1 3.0 3 1 0 4 4 3 1 AAA ATPase domain AAA_7 PF12775.7 EWM22441.1 - 0.0019 17.8 0.0 0.26 10.8 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 EWM22441.1 - 0.0027 17.9 0.0 0.0067 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 EWM22441.1 - 0.011 15.1 0.0 1.1 8.6 0.1 2.4 2 0 0 2 2 2 0 Bacterial TniB protein DUF815 PF05673.13 EWM22441.1 - 0.012 14.8 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 EWM22441.1 - 0.013 15.2 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EWM22441.1 - 0.015 14.7 0.1 0.029 13.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EWM22441.1 - 0.015 15.3 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EWM22441.1 - 0.023 15.0 0.0 0.043 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EWM22441.1 - 0.025 15.0 0.1 0.065 13.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain TPR_5 PF12688.7 EWM22441.1 - 0.03 14.5 0.7 0.07 13.4 0.7 1.6 1 0 0 1 1 1 0 Tetratrico peptide repeat NTPase_1 PF03266.15 EWM22441.1 - 0.037 13.9 0.1 29 4.5 0.1 3.2 2 1 0 3 3 3 0 NTPase ATPase PF06745.13 EWM22441.1 - 0.067 12.5 0.4 1.4 8.2 0.1 2.1 1 1 0 2 2 2 0 KaiC PhoH PF02562.16 EWM22441.1 - 0.11 11.9 0.1 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.22 EWM22441.1 - 0.12 12.8 0.0 0.27 11.6 0.0 1.7 1 1 0 1 1 1 0 RNA helicase RNase_P_p30 PF01876.16 EWM22442.1 - 6.1e-37 127.2 0.0 9.4e-37 126.6 0.0 1.3 1 1 0 1 1 1 1 RNase P subunit p30 Tic22 PF04278.12 EWM22443.1 - 5.6e-10 39.0 0.0 2.5e-09 36.9 0.0 1.8 1 1 0 1 1 1 1 Tic22-like family CHASE8 PF17152.4 EWM22443.1 - 0.039 14.2 0.0 0.083 13.1 0.0 1.4 1 0 0 1 1 1 0 Periplasmic sensor domain FBPase PF00316.20 EWM22444.1 - 6.4e-70 234.5 0.2 1.3e-69 233.5 0.2 1.5 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Helicase_C PF00271.31 EWM22445.1 - 5.6e-18 65.3 0.1 1.8e-17 63.6 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 EWM22445.1 - 6.5e-14 52.1 0.7 1.7e-13 50.8 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EWM22445.1 - 1.8e-12 47.4 0.0 4.1e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EWM22445.1 - 6e-08 32.7 0.5 1.8e-07 31.1 0.0 2.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase T2SSE PF00437.20 EWM22445.1 - 0.0016 17.5 0.0 0.003 16.7 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 EWM22445.1 - 0.0032 17.2 0.0 0.0083 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EWM22445.1 - 0.0053 17.1 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EWM22445.1 - 0.006 16.5 0.2 0.03 14.3 0.0 2.3 2 0 0 2 2 2 1 NACHT domain PhoH PF02562.16 EWM22445.1 - 0.07 12.6 0.0 0.68 9.4 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_11 PF13086.6 EWM22445.1 - 0.34 10.7 0.0 0.34 10.7 0.0 3.2 2 1 0 2 2 1 0 AAA domain AAA_23 PF13476.6 EWM22445.1 - 4.3 7.8 6.7 23 5.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain Glyco_hydro_47 PF01532.20 EWM22446.1 - 2.3e-127 425.7 0.1 2.2e-126 422.5 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 SepRS_C PF18006.1 EWM22446.1 - 0.085 13.0 0.1 0.26 11.4 0.1 1.8 1 0 0 1 1 1 0 O-phosphoseryl-tRNA synthetase C-terminal domain Cpn60_TCP1 PF00118.24 EWM22447.1 - 2.1e-149 498.3 7.3 2.4e-149 498.1 7.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family EAP30 PF04157.16 EWM22448.1 - 1.5e-38 132.5 0.3 1.8e-38 132.1 0.3 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 EWM22448.1 - 2.8e-10 40.2 0.0 4.6e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 SMC_ScpB PF04079.16 EWM22451.1 - 0.11 12.2 0.0 0.33 10.6 0.0 1.8 2 0 0 2 2 2 0 Segregation and condensation complex subunit ScpB SASRP1 PF15160.6 EWM22452.1 - 0.032 13.9 0.1 0.06 13.0 0.1 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated serine-rich protein 1 CBM9_1 PF06452.11 EWM22453.1 - 1.8e-06 28.0 1.3 2.7e-06 27.4 1.3 1.2 1 0 0 1 1 1 1 Carbohydrate family 9 binding domain-like CBM9_2 PF16011.5 EWM22453.1 - 0.00028 20.6 0.0 0.00065 19.5 0.1 1.5 2 0 0 2 2 2 1 Carbohydrate-binding family 9 S1 PF00575.23 EWM22454.1 - 1.7e-19 70.0 0.2 1.6e-08 34.8 0.0 3.2 2 1 1 3 3 3 3 S1 RNA binding domain DUF1104 PF06518.11 EWM22454.1 - 0.53 10.7 5.5 1.1 9.7 5.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) AAA PF00004.29 EWM22455.1 - 1.5e-42 145.1 0.2 5.5e-42 143.3 0.0 2.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EWM22455.1 - 1e-12 47.6 0.1 3.1e-12 46.1 0.0 1.9 2 0 0 2 2 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EWM22455.1 - 7.7e-07 29.0 0.6 1.9e-06 27.7 0.6 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 EWM22455.1 - 1.1e-06 28.9 0.0 2.9e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EWM22455.1 - 2.4e-06 27.6 0.0 1e-05 25.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EWM22455.1 - 1.1e-05 25.9 0.1 0.00021 21.7 0.1 2.6 2 1 0 3 3 2 1 AAA ATPase domain RuvB_N PF05496.12 EWM22455.1 - 0.00011 22.0 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EWM22455.1 - 0.00013 22.3 0.9 0.012 15.8 0.0 3.2 3 1 1 4 4 4 1 AAA domain AAA_33 PF13671.6 EWM22455.1 - 0.00084 19.5 0.0 0.0058 16.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EWM22455.1 - 0.0038 17.0 0.0 0.007 16.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 EWM22455.1 - 0.0051 16.1 0.0 0.0096 15.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 EWM22455.1 - 0.0066 17.0 0.1 0.028 15.0 0.0 2.2 3 0 0 3 3 1 1 AAA domain AAA_3 PF07726.11 EWM22455.1 - 0.0068 16.3 0.0 0.019 14.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EWM22455.1 - 0.0075 15.7 0.0 0.17 11.3 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 EWM22455.1 - 0.0078 15.6 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EWM22455.1 - 0.0085 16.3 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EWM22455.1 - 0.01 15.6 0.0 0.07 12.8 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain TsaE PF02367.17 EWM22455.1 - 0.019 15.0 0.0 0.039 14.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EWM22455.1 - 0.027 14.8 0.0 0.055 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 EWM22455.1 - 0.036 13.8 0.3 0.083 12.6 0.0 1.9 2 1 0 2 2 1 0 AAA domain Zeta_toxin PF06414.12 EWM22455.1 - 0.039 13.2 0.1 0.3 10.3 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 EWM22455.1 - 0.041 13.4 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 EWM22455.1 - 0.041 13.0 0.0 0.088 11.9 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF815 PF05673.13 EWM22455.1 - 0.045 12.9 0.0 0.079 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 EWM22455.1 - 0.065 12.8 0.1 0.19 11.3 0.1 1.7 2 0 0 2 2 1 0 AAA domain DUF4482 PF14818.6 EWM22455.1 - 0.066 14.1 0.1 0.18 12.7 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) AAA_19 PF13245.6 EWM22455.1 - 0.07 13.5 0.5 0.48 10.8 0.1 2.5 3 0 0 3 3 3 0 AAA domain ATPase PF06745.13 EWM22455.1 - 0.082 12.2 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.6 EWM22455.1 - 0.086 12.9 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EWM22455.1 - 0.1 12.5 0.0 0.64 9.9 0.0 2.3 3 0 0 3 3 2 0 RsgA GTPase AAA_11 PF13086.6 EWM22455.1 - 0.14 11.9 0.1 0.44 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF2072 PF09845.9 EWM22455.1 - 0.18 12.1 0.1 0.34 11.2 0.1 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein Tropomyosin PF00261.20 EWM22455.1 - 0.21 10.9 2.9 0.54 9.6 0.9 2.0 2 0 0 2 2 2 0 Tropomyosin DUF1090 PF06476.12 EWM22455.1 - 0.28 11.3 1.8 3.3 7.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) Cyclin_N PF00134.23 EWM22456.1 - 8.3e-13 48.2 0.0 7.3e-12 45.1 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain E7R PF17467.2 EWM22456.1 - 0.025 14.7 0.7 0.04 14.1 0.7 1.3 1 0 0 1 1 1 0 Viral Protein E7 ApoA-II PF04711.13 EWM22456.1 - 0.11 12.7 0.0 1 9.6 0.0 2.1 2 0 0 2 2 2 0 Apolipoprotein A-II (ApoA-II) betaPIX_CC PF16523.5 EWM22456.1 - 0.15 11.9 0.3 4 7.3 0.0 2.2 2 0 0 2 2 2 0 betaPIX coiled coil HSP70 PF00012.20 EWM22457.1 - 7.1e-258 856.7 12.8 8.1e-258 856.5 12.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EWM22457.1 - 3.5e-17 62.2 1.1 5.2e-16 58.4 0.4 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Radial_spoke_3 PF06098.11 EWM22457.1 - 0.0039 16.5 6.1 0.0039 16.5 6.1 1.5 2 0 0 2 2 2 1 Radial spoke protein 3 FGGY_C PF02782.16 EWM22457.1 - 0.0064 16.2 0.0 0.023 14.4 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 EWM22457.1 - 0.014 14.4 1.2 0.18 10.8 1.0 2.5 1 1 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 EWM22457.1 - 0.036 13.3 1.0 0.23 10.7 0.1 2.3 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase FtsA PF14450.6 EWM22457.1 - 0.18 12.2 3.7 1.3 9.4 0.6 3.3 2 1 0 2 2 2 0 Cell division protein FtsA Pex19 PF04614.12 EWM22457.1 - 0.86 9.3 8.0 0.3 10.8 5.0 1.7 2 0 0 2 2 2 0 Pex19 protein family SPOUT_MTase PF02590.17 EWM22458.1 - 4.2e-32 111.3 0.0 7.8e-32 110.4 0.0 1.5 1 1 0 1 1 1 1 Predicted SPOUT methyltransferase Mo25 PF08569.11 EWM22460.1 - 5e-115 384.3 0.4 7.7e-115 383.7 0.4 1.2 1 0 0 1 1 1 1 Mo25-like Fanconi_A_N PF15865.5 EWM22460.1 - 0.016 14.6 0.1 0.029 13.8 0.1 1.4 1 0 0 1 1 1 0 Fanconi anaemia group A protein N terminus ZYG-11_interact PF05884.12 EWM22460.1 - 0.19 11.1 0.0 0.74 9.2 0.1 1.8 2 0 0 2 2 2 0 Interactor of ZYG-11 Mo25 PF08569.11 EWM22461.1 - 6.8e-115 383.9 0.6 1e-114 383.3 0.6 1.2 1 0 0 1 1 1 1 Mo25-like Fanconi_A_N PF15865.5 EWM22461.1 - 0.018 14.4 0.1 0.032 13.6 0.1 1.4 1 0 0 1 1 1 0 Fanconi anaemia group A protein N terminus GFO_IDH_MocA PF01408.22 EWM22462.1 - 1.8e-23 83.6 0.0 2.7e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EWM22462.1 - 2.6e-11 43.5 0.0 6.2e-11 42.3 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Peripla_BP_1 PF00532.21 EWM22462.1 - 0.0032 16.9 0.0 0.0052 16.2 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family NAD_binding_3 PF03447.16 EWM22462.1 - 0.078 13.6 0.0 0.14 12.8 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EWM22462.1 - 0.14 12.4 0.1 0.5 10.6 0.1 1.9 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TPR_12 PF13424.6 EWM22463.1 - 4.8e-10 39.6 25.7 6.3e-05 23.2 2.2 7.7 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 EWM22463.1 - 1.3e-09 38.5 12.5 1.3 9.6 0.1 7.9 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 EWM22463.1 - 9.4e-09 34.7 27.9 0.43 10.8 0.2 9.4 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_14 PF13428.6 EWM22463.1 - 6.5e-07 29.6 10.5 0.21 12.5 0.0 8.0 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 EWM22463.1 - 2.8e-05 23.8 6.5 1.7 8.8 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 EWM22463.1 - 4.6e-05 23.1 30.6 0.28 11.1 0.4 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 EWM22463.1 - 0.00022 21.3 2.2 0.39 10.9 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 EWM22463.1 - 0.00046 19.5 1.8 4 6.6 0.1 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 EWM22463.1 - 0.0065 16.3 11.9 0.24 11.3 0.1 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 EWM22463.1 - 0.0073 16.9 14.7 4.1 8.1 0.0 6.5 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.14 EWM22463.1 - 0.022 15.4 13.1 3.2 8.7 0.1 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EWM22463.1 - 0.048 13.7 0.7 11 6.1 0.1 3.6 4 0 0 4 4 4 0 Putative TPR-like repeat ANAPC3 PF12895.7 EWM22463.1 - 0.12 12.6 17.7 0.74 10.1 0.9 6.0 6 0 0 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EWM22463.1 - 0.55 10.6 14.2 1.9 8.9 0.0 5.5 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EWM22463.1 - 0.99 10.2 11.9 15 6.4 0.2 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 EWM22463.1 - 1.2 8.9 6.3 3.8 7.3 0.1 4.3 4 0 0 4 4 4 0 TPR repeat DUF1325 PF07039.11 EWM22464.1 - 1.5e-24 86.6 0.0 2.1e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain SAP30_Sin3_bdg PF13867.6 EWM22464.1 - 1.1e-10 41.7 0.0 1.9e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Forkhead PF00250.18 EWM22464.1 - 0.0046 17.2 0.0 0.0092 16.2 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain DUF4537 PF15057.6 EWM22464.1 - 0.058 13.4 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) Ish1 PF10281.9 EWM22464.1 - 0.18 12.1 0.1 0.32 11.3 0.1 1.4 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein IBR PF01485.21 EWM22465.1 - 5.3e-17 61.8 27.6 9.4e-10 38.6 14.1 4.3 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 EWM22465.1 - 6e-07 29.7 3.1 6e-07 29.7 3.1 4.2 2 1 1 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 EWM22465.1 - 4.5e-05 23.4 2.5 4.5e-05 23.4 2.5 4.1 3 1 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 EWM22465.1 - 7.1e-05 22.7 5.9 7.1e-05 22.7 5.9 3.8 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EWM22465.1 - 9.5e-05 22.2 0.4 9.5e-05 22.2 0.4 4.5 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EWM22465.1 - 0.0011 18.8 1.4 0.0011 18.8 1.4 4.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EWM22465.1 - 0.0094 15.8 3.7 0.0094 15.8 3.7 4.3 2 1 2 4 4 4 1 Prokaryotic RING finger family 4 MFS_1 PF07690.16 EWM22466.1 - 1.6e-38 132.6 26.9 3.5e-30 105.1 7.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EWM22466.1 - 2e-06 27.0 12.5 6.3e-06 25.3 12.5 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 EWM22466.1 - 0.00028 19.4 6.6 0.00061 18.3 1.8 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector RRM_1 PF00076.22 EWM22467.1 - 1.1e-45 153.3 0.0 1.1e-16 60.3 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EWM22467.1 - 1.4e-05 25.1 0.0 0.0068 16.5 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif Limkain-b1 PF11608.8 EWM22467.1 - 0.00011 22.2 0.1 0.12 12.5 0.1 2.7 2 1 0 2 2 2 2 Limkain b1 RRM_3 PF08777.11 EWM22467.1 - 0.0088 16.1 0.0 0.77 9.8 0.0 2.9 2 1 1 3 3 3 1 RNA binding motif DUF2471 PF10616.9 EWM22467.1 - 0.11 13.1 0.2 11 6.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2471) Rtf2 PF04641.12 EWM22468.1 - 1.6e-52 178.5 0.2 4.6e-52 177.0 0.2 1.6 1 1 0 1 1 1 1 Rtf2 RING-finger zf-NOSIP PF15906.5 EWM22468.1 - 0.0096 16.0 0.0 0.021 15.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein PIGA PF08288.12 EWM22469.1 - 4.5e-41 139.4 1.2 2.1e-40 137.2 0.8 2.3 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 EWM22469.1 - 6.8e-31 107.5 0.3 1.2e-30 106.7 0.3 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 EWM22469.1 - 4.9e-23 81.5 0.0 7.9e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EWM22469.1 - 1.6e-21 77.1 0.3 3.1e-21 76.2 0.1 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EWM22469.1 - 3.7e-14 53.5 0.2 1.3e-13 51.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 EWM22469.1 - 0.0015 18.6 0.1 0.0031 17.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 EWM22469.1 - 0.0023 18.3 0.0 0.0061 16.9 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Ub-Mut7C PF14451.6 EWM22469.1 - 0.048 13.5 0.4 0.4 10.6 0.0 2.4 2 0 0 2 2 2 0 Mut7-C ubiquitin Glyco_transf_5 PF08323.11 EWM22469.1 - 0.056 13.1 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Starch synthase catalytic domain DENN PF02141.21 EWM22471.1 - 1.2e-24 87.3 3.7 3.4e-21 76.0 1.0 2.4 2 0 0 2 2 2 2 DENN (AEX-3) domain uDENN PF03456.18 EWM22471.1 - 9.2e-06 26.3 0.0 2.8e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 EWM22471.1 - 0.008 16.2 0.4 0.02 14.9 0.4 1.7 1 0 0 1 1 1 1 dDENN domain Herpes_BLRF2 PF05812.12 EWM22471.1 - 0.05 13.7 0.2 0.14 12.3 0.2 1.8 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein GIT_CC PF16559.5 EWM22471.1 - 0.49 10.3 1.5 0.96 9.4 1.5 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF3007 PF11460.8 EWM22472.1 - 4.3e-30 103.8 1.1 4.3e-30 103.8 1.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3007) DUF1772 PF08592.11 EWM22472.1 - 0.0064 16.8 1.9 0.024 14.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1772) Thioesterase PF00975.20 EWM22473.1 - 1.4e-19 71.1 0.0 2.8e-19 70.1 0.0 1.4 2 0 0 2 2 2 1 Thioesterase domain DUF900 PF05990.12 EWM22473.1 - 0.005 16.4 0.0 0.0098 15.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) LIDHydrolase PF10230.9 EWM22473.1 - 0.014 15.0 0.0 0.031 13.8 0.0 1.6 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase AAA PF00004.29 EWM22474.1 - 2.5e-43 147.7 0.0 2e-35 122.1 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EWM22474.1 - 1.2e-07 32.2 10.4 0.0025 18.2 0.1 4.8 3 2 2 5 5 5 2 AAA ATPase domain AAA_5 PF07728.14 EWM22474.1 - 2.6e-07 30.7 0.0 0.00084 19.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 EWM22474.1 - 7.7e-07 28.8 1.2 0.0099 15.7 0.1 2.7 3 0 0 3 3 3 2 AAA+ lid domain AAA_22 PF13401.6 EWM22474.1 - 4.8e-06 26.9 0.5 0.13 12.5 0.1 3.5 2 2 1 3 3 3 2 AAA domain TIP49 PF06068.13 EWM22474.1 - 2.4e-05 23.7 0.0 0.00085 18.6 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain RuvB_N PF05496.12 EWM22474.1 - 9.5e-05 22.2 0.0 0.025 14.3 0.0 3.0 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EWM22474.1 - 0.0001 22.6 0.0 0.011 16.1 0.0 2.3 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.21 EWM22474.1 - 0.00016 21.1 0.3 0.69 9.3 0.0 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.12 EWM22474.1 - 0.00026 21.0 0.0 0.58 10.1 0.0 3.4 3 0 0 3 3 3 1 NACHT domain AAA_2 PF07724.14 EWM22474.1 - 0.00027 21.1 0.0 0.54 10.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) TsaE PF02367.17 EWM22474.1 - 0.0017 18.3 0.0 0.58 10.2 0.0 2.7 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 EWM22474.1 - 0.0043 17.0 0.0 0.17 11.8 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_33 PF13671.6 EWM22474.1 - 0.0048 17.1 0.0 0.054 13.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EWM22474.1 - 0.0075 16.0 0.1 0.98 9.1 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain ABC_tran PF00005.27 EWM22474.1 - 0.055 14.0 2.3 0.13 12.7 0.2 2.5 3 0 0 3 3 3 0 ABC transporter Cytidylate_kin PF02224.18 EWM22474.1 - 0.061 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase AAA_18 PF13238.6 EWM22474.1 - 0.079 13.5 0.0 2.3 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 EWM22474.1 - 0.17 12.0 0.0 27 4.9 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 EWM22474.1 - 0.2 11.4 0.6 2.7 7.7 0.2 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein DnaB_C PF03796.15 EWM22474.1 - 0.2 10.9 0.0 0.63 9.3 0.0 1.8 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain DUF1499 PF07386.11 EWM22476.1 - 1.1e-09 38.8 0.0 1.7e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1499) PRA1 PF03208.19 EWM22476.1 - 0.067 12.8 5.3 0.12 12.0 5.3 1.3 1 0 0 1 1 1 0 PRA1 family protein TOM13 PF08219.11 EWM22476.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Outer membrane protein TOM13 SelK_SelG PF10961.8 EWM22477.1 - 0.0049 17.4 0.4 0.0049 17.4 0.4 1.6 2 0 0 2 2 2 1 Selenoprotein SelK_SelG CBFD_NFYB_HMF PF00808.23 EWM22478.1 - 0.011 16.1 0.1 0.042 14.1 0.0 1.9 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DsbD PF02683.15 EWM22479.1 - 4.5e-36 124.8 9.4 7.5e-36 124.0 9.4 1.3 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DsbD_2 PF13386.6 EWM22479.1 - 1.3e-09 38.3 17.2 1.2e-08 35.2 16.6 2.5 2 1 1 3 3 3 2 Cytochrome C biogenesis protein transmembrane region Trp_oprn_chp PF09534.10 EWM22479.1 - 0.18 11.5 0.0 0.18 11.5 0.0 3.0 2 1 1 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4477 PF14780.6 EWM22481.1 - 2.3e-06 27.4 2.8 4.2e-06 26.5 2.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) DC_STAMP PF07782.13 EWM22481.1 - 0.94 9.3 3.7 0.44 10.3 0.3 1.9 1 1 1 2 2 2 0 DC-STAMP-like protein Pro_isomerase PF00160.21 EWM22482.1 - 2.6e-50 170.7 0.0 6.5e-50 169.5 0.0 1.7 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 EWM22482.1 - 4.2e-09 36.1 1.9 4.2e-09 36.1 1.9 2.3 2 1 0 2 2 2 1 Rtf2 RING-finger zf-NOSIP PF15906.5 EWM22482.1 - 0.00097 19.2 0.0 0.0026 17.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein UDG PF03167.19 EWM22483.1 - 2.5e-37 128.3 0.0 3.5e-37 127.8 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Aldo_ket_red PF00248.21 EWM22484.1 - 3.8e-42 144.5 0.0 1.1e-41 143.0 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family PX PF00787.24 EWM22485.1 - 0.038 14.0 0.0 0.079 13.0 0.0 1.5 1 0 0 1 1 1 0 PX domain DUF5101 PF17031.5 EWM22485.1 - 0.93 9.6 5.4 0.95 9.6 0.5 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5101) DUF3450 PF11932.8 EWM22485.1 - 5.3 6.3 32.5 0.58 9.4 10.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) Cep57_MT_bd PF06657.13 EWM22485.1 - 6.1 7.4 12.3 0.24 11.9 1.9 3.1 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 zf-RING_2 PF13639.6 EWM22486.1 - 5.4e-11 42.7 6.9 1.1e-10 41.7 6.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EWM22486.1 - 9.7e-08 32.2 9.5 3.4e-07 30.5 9.5 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EWM22486.1 - 5.1e-07 29.4 6.6 9.1e-07 28.6 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EWM22486.1 - 8.6e-07 28.9 3.2 2.1e-06 27.6 3.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 EWM22486.1 - 4.2e-06 26.4 1.7 9.1e-06 25.3 1.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 EWM22486.1 - 9e-06 25.5 4.6 2e-05 24.4 4.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EWM22486.1 - 0.00026 20.9 3.6 0.00026 20.9 3.6 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EWM22486.1 - 0.0006 19.8 1.7 0.0013 18.7 1.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EWM22486.1 - 0.0013 18.6 7.0 0.0026 17.6 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EWM22486.1 - 0.0054 16.3 5.4 0.012 15.2 5.4 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 EWM22486.1 - 0.0095 16.2 2.8 0.016 15.5 2.8 1.3 1 0 0 1 1 1 1 RING-like domain Prok-RING_4 PF14447.6 EWM22486.1 - 0.045 13.6 9.9 0.04 13.8 7.3 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-P11 PF03854.14 EWM22486.1 - 0.16 11.7 2.2 0.45 10.2 2.2 1.7 1 0 0 1 1 1 0 P-11 zinc finger zf-HC5HC2H PF13771.6 EWM22486.1 - 0.83 9.9 2.9 0.98 9.7 1.7 1.6 2 0 0 2 2 1 0 PHD-like zinc-binding domain zf-C3HC4_4 PF15227.6 EWM22486.1 - 1 9.5 4.6 2.1 8.5 4.6 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3H2C3 PF17122.5 EWM22486.1 - 2.2 8.4 4.4 1 9.4 1.7 1.9 2 0 0 2 2 1 0 Zinc-finger RINGv PF12906.7 EWM22486.1 - 6.7 6.9 8.0 1.9 8.7 4.9 1.7 2 0 0 2 2 1 0 RING-variant domain zf-RING_4 PF14570.6 EWM22486.1 - 7.4 6.5 6.1 13 5.7 5.1 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Methyltransf_16 PF10294.9 EWM22487.1 - 8.3e-18 64.7 0.2 2.6e-16 59.8 0.2 2.1 1 1 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 EWM22487.1 - 2.6e-05 23.8 0.0 4.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EWM22487.1 - 0.022 15.4 0.0 0.051 14.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 EWM22487.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein ATP-synt_D PF01813.17 EWM22488.1 - 2.8e-62 210.0 1.9 2.8e-62 210.0 1.9 1.3 2 0 0 2 2 2 1 ATP synthase subunit D Borrelia_lipo_1 PF05714.11 EWM22488.1 - 0.047 13.4 0.8 0.075 12.8 0.2 1.6 2 0 0 2 2 2 0 Borrelia burgdorferi virulent strain associated lipoprotein DUF1451 PF07295.11 EWM22488.1 - 0.13 12.3 0.6 0.48 10.4 0.5 1.9 1 1 0 1 1 1 0 Zinc-ribbon containing domain DUF5446 PF17522.2 EWM22488.1 - 0.21 11.8 0.5 0.51 10.5 0.5 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5446) MnmE_helical PF12631.7 EWM22489.1 - 3.7e-50 171.0 0.0 4.4e-50 170.7 0.0 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 EWM22489.1 - 1.8e-26 92.7 0.0 1.1e-25 90.2 0.0 2.2 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 EWM22489.1 - 1.3e-19 70.4 0.0 3.1e-19 69.1 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EWM22489.1 - 3.8e-06 26.5 0.0 6.1e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EWM22489.1 - 2.5e-05 24.4 0.0 4.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Dynamin family ABC_tran PF00005.27 EWM22489.1 - 0.0024 18.4 0.0 0.0048 17.4 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_28 PF13521.6 EWM22489.1 - 0.0035 17.6 0.0 0.0099 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EWM22489.1 - 0.0057 16.4 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EWM22489.1 - 0.0081 16.4 0.0 0.023 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain Arf PF00025.21 EWM22489.1 - 0.026 14.0 0.0 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_25 PF13481.6 EWM22489.1 - 0.043 13.4 1.9 0.089 12.4 0.3 2.5 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EWM22489.1 - 0.1 13.1 0.0 0.49 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EWM22489.1 - 0.12 12.7 1.9 1.2 9.5 0.3 2.7 1 1 1 2 2 2 0 AAA ATPase domain AIG1 PF04548.16 EWM22489.1 - 0.19 11.0 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 AIG1 family CHAD PF05235.14 EWM22489.1 - 0.49 10.3 5.4 0.23 11.4 0.5 2.2 2 1 0 2 2 2 0 CHAD domain TIM PF00121.18 EWM22490.1 - 3.5e-10 39.7 0.0 4.2e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase Acetyltransf_1 PF00583.25 EWM22493.1 - 1.5e-10 41.4 0.1 1.8e-10 41.0 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EWM22493.1 - 4.1e-07 30.3 0.4 6.7e-07 29.6 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EWM22493.1 - 3.5e-06 26.9 0.0 5.7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 EWM22493.1 - 3.6e-06 26.9 0.1 4.6e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EWM22493.1 - 0.00033 20.7 0.1 0.00084 19.4 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EWM22493.1 - 0.047 13.8 0.0 0.061 13.5 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PRP21_like_P PF12230.8 EWM22494.1 - 6.9e-35 120.9 0.0 1.3e-34 120.0 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 EWM22494.1 - 1.8e-34 117.5 1.1 2.4e-16 59.4 0.1 2.4 2 0 0 2 2 2 2 Surp module PAN_4 PF14295.6 EWM22495.1 - 0.00068 19.5 0.7 0.0018 18.2 0.7 1.7 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 EWM22495.1 - 0.16 12.0 1.2 0.31 11.0 1.2 1.5 1 0 0 1 1 1 0 PAN domain tRNA-synt_1b PF00579.25 EWM22497.1 - 3.6e-74 249.7 0.0 4.6e-74 249.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 EWM22497.1 - 8e-05 22.3 0.0 0.00025 20.7 0.0 1.8 1 0 0 1 1 1 1 S4 domain Med21 PF11221.8 EWM22498.1 - 0.00082 19.6 3.0 0.15 12.3 1.3 2.2 1 1 0 2 2 2 2 Subunit 21 of Mediator complex Bestrophin PF01062.21 EWM22501.1 - 4.2e-18 65.8 0.1 5.5e-18 65.4 0.1 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Glycos_transf_1 PF00534.20 EWM22501.1 - 0.00065 19.3 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 BATS PF06968.13 EWM22502.1 - 0.023 14.8 0.0 0.026 14.7 0.0 1.1 1 0 0 1 1 1 0 Biotin and Thiamin Synthesis associated domain TMF_DNA_bd PF12329.8 EWM22503.1 - 2e-05 24.5 12.6 2e-05 24.5 12.6 5.1 5 2 2 7 7 7 1 TATA element modulatory factor 1 DNA binding T2SSF PF00482.23 EWM22503.1 - 0.36 10.8 8.5 1.7 8.6 1.0 3.0 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein F DUF812 PF05667.11 EWM22503.1 - 0.54 9.1 38.5 8.8 5.1 38.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF4407 PF14362.6 EWM22503.1 - 1.1 8.5 35.3 3 7.1 15.4 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF4359 PF14271.6 EWM22503.1 - 1.8 9.3 0.0 1.8 9.3 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4359) FliJ PF02050.16 EWM22503.1 - 5.7 7.2 47.9 0.021 15.0 16.0 4.3 4 1 1 5 5 5 0 Flagellar FliJ protein Pkinase PF00069.25 EWM22504.1 - 3.7e-53 180.6 0.0 5.2e-53 180.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM22504.1 - 5e-25 88.3 0.0 7.4e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EWM22504.1 - 0.00068 18.7 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EWM22504.1 - 0.0043 16.4 0.1 0.024 14.0 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EWM22504.1 - 0.0056 16.0 0.0 0.0097 15.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pinin_SDK_N PF04697.13 EWM22504.1 - 0.088 13.5 0.1 0.088 13.5 0.1 2.2 2 0 0 2 2 2 0 pinin/SDK conserved region HA2 PF04408.23 EWM22506.1 - 1.7e-25 89.4 2.5 3.4e-25 88.4 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EWM22506.1 - 2.7e-13 50.3 0.0 5.4e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EWM22506.1 - 2.1e-11 44.0 0.2 8.2e-11 42.1 0.0 2.1 3 0 0 3 3 3 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EWM22506.1 - 1.4e-05 24.9 0.1 0.00014 21.7 0.1 2.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EWM22506.1 - 0.045 14.0 0.2 0.31 11.3 0.1 2.4 2 1 0 2 2 2 0 AAA domain HA2 PF04408.23 EWM22507.1 - 9.3e-26 90.2 0.0 2.1e-25 89.1 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EWM22507.1 - 1.6e-13 50.9 0.0 3.2e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EWM22507.1 - 1e-11 45.0 0.2 5.2e-11 42.8 0.0 2.2 3 0 0 3 3 3 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Pkinase PF00069.25 EWM22508.1 - 1.5e-34 119.6 0.0 5.3e-34 117.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM22508.1 - 1.7e-19 70.1 0.0 2.5e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase NUDIX PF00293.28 EWM22509.1 - 1.3e-13 51.1 0.3 3.3e-13 49.8 0.3 1.6 1 0 0 1 1 1 1 NUDIX domain Herpes_UL56 PF04534.12 EWM22509.1 - 7.4 6.0 9.2 0.4 10.1 3.0 2.0 2 0 0 2 2 2 0 Herpesvirus UL56 protein TIM PF00121.18 EWM22510.1 - 3.5e-27 95.4 0.2 3.9e-27 95.2 0.2 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase DUF3046 PF11248.8 EWM22510.1 - 0.17 12.3 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3046) RPN7 PF10602.9 EWM22511.1 - 0.16 11.6 2.7 0.14 11.8 0.4 2.0 2 1 1 3 3 3 0 26S proteasome subunit RPN7 PCI PF01399.27 EWM22513.1 - 2.7e-16 60.0 0.0 3.5e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 PCI domain CSN4_RPN5_eIF3a PF18420.1 EWM22513.1 - 0.15 12.3 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 CSN4/RPN5/eIF3a helix turn helix domain mTERF PF02536.14 EWM22514.1 - 0.0033 16.4 0.1 0.3 10.0 0.0 3.4 2 1 0 2 2 2 1 mTERF mTERF PF02536.14 EWM22515.1 - 0.0053 15.7 0.0 0.37 9.7 0.0 3.3 2 1 0 2 2 2 1 mTERF Sod_Fe_C PF02777.18 EWM22517.1 - 8.2e-40 135.1 2.7 1.1e-39 134.8 0.1 2.1 3 0 0 3 3 3 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EWM22517.1 - 3.2e-29 101.2 0.4 6.4e-29 100.3 0.4 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Abhydrolase_1 PF00561.20 EWM22518.1 - 0.002 17.8 0.0 0.0028 17.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold TPR_2 PF07719.17 EWM22520.1 - 4.2e-20 70.2 6.6 1.1e-06 28.2 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EWM22520.1 - 3.9e-17 61.3 0.2 2.2e-07 30.4 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EWM22520.1 - 2.5e-16 58.5 0.7 0.00011 22.1 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 EWM22520.1 - 7.6e-16 58.5 34.7 9.9e-10 38.9 1.1 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 EWM22520.1 - 1e-15 57.0 12.7 0.00013 22.4 0.8 4.2 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.6 EWM22520.1 - 2.9e-12 46.0 1.2 0.00049 20.3 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EWM22520.1 - 3.1e-12 46.8 5.7 3e-05 24.4 0.9 3.3 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 EWM22520.1 - 1.6e-11 43.3 5.2 0.0071 16.3 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 EWM22520.1 - 7e-11 42.3 12.5 0.0046 17.2 4.2 3.5 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EWM22520.1 - 8e-11 41.5 3.6 0.00027 20.6 0.0 4.1 2 2 2 4 4 4 3 TPR repeat TPR_10 PF13374.6 EWM22520.1 - 3.5e-07 29.9 11.0 0.076 12.9 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 EWM22520.1 - 4.4e-07 29.9 4.2 0.002 18.3 0.5 2.4 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 EWM22520.1 - 1e-06 28.9 7.2 0.078 13.7 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EWM22520.1 - 0.0028 17.9 2.5 0.93 9.8 0.2 2.2 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 EWM22520.1 - 0.0031 18.0 0.3 0.25 12.1 0.0 4.2 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EWM22520.1 - 0.0051 16.2 8.3 0.35 10.2 5.2 2.8 1 1 1 2 2 2 1 MalT-like TPR region TPR_20 PF14561.6 EWM22520.1 - 0.015 15.7 2.2 0.73 10.2 0.9 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat 4HB_MCP_1 PF12729.7 EWM22520.1 - 0.095 12.2 0.2 0.28 10.7 0.0 1.9 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction BTAD PF03704.17 EWM22520.1 - 0.1 13.0 8.6 0.32 11.4 0.1 2.8 1 1 1 3 3 3 0 Bacterial transcriptional activator domain GatB_N PF02934.15 EWM22521.1 - 3.8e-86 288.9 0.0 4.7e-86 288.6 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 EWM22521.1 - 2.7e-23 82.5 0.0 1.4e-22 80.2 0.0 2.2 2 1 0 2 2 2 1 GatB domain AAA_12 PF13087.6 EWM22523.1 - 7.6e-56 188.9 0.0 9.9e-56 188.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EWM22523.1 - 4.1e-31 108.7 0.3 3.2e-30 105.8 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EWM22523.1 - 0.0012 18.6 0.0 0.0031 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EWM22523.1 - 0.0076 16.0 0.0 0.87 9.3 0.0 2.2 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase BAAT_C PF08840.11 EWM22525.1 - 0.068 13.1 0.0 0.087 12.7 0.0 1.1 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal BAAT_C PF08840.11 EWM22526.1 - 0.068 13.1 0.0 0.087 12.7 0.0 1.1 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal CDC45 PF02724.14 EWM22527.1 - 0.00056 18.4 30.5 0.00072 18.0 30.5 1.0 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 EWM22527.1 - 0.00096 17.5 22.1 0.0012 17.2 22.1 1.1 1 0 0 1 1 1 1 Nop14-like family YL1 PF05764.13 EWM22527.1 - 0.0012 19.0 30.3 0.0018 18.5 30.3 1.2 1 0 0 1 1 1 1 YL1 nuclear protein Nop53 PF07767.11 EWM22527.1 - 0.002 17.6 35.1 0.0028 17.1 35.1 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) TFIIA PF03153.13 EWM22527.1 - 0.0085 16.1 7.8 0.011 15.8 7.8 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PPP4R2 PF09184.11 EWM22527.1 - 0.084 12.5 19.9 0.11 12.1 19.9 1.1 1 0 0 1 1 1 0 PPP4R2 Merozoite_SPAM PF07133.11 EWM22527.1 - 0.15 12.0 33.3 0.22 11.5 33.3 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) SDA1 PF05285.12 EWM22527.1 - 0.39 10.1 28.4 0.6 9.5 28.4 1.2 1 0 0 1 1 1 0 SDA1 DUF2722 PF10846.8 EWM22527.1 - 0.69 8.8 6.0 0.85 8.5 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DNA_pol_phi PF04931.13 EWM22527.1 - 1.5 6.8 36.0 2 6.4 36.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi IFT57 PF10498.9 EWM22527.1 - 1.7 7.5 12.5 2.3 7.1 12.5 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 CDC27 PF09507.10 EWM22527.1 - 2.2 7.6 22.9 3.9 6.8 22.9 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Rhabdo_ncap PF00945.18 EWM22527.1 - 2.8 6.7 5.5 3.9 6.3 5.5 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein RR_TM4-6 PF06459.12 EWM22527.1 - 3.6 7.3 13.1 5.1 6.8 13.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 EWM22527.1 - 4.2 6.3 5.0 5.5 5.9 5.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Pes-10 PF07149.11 EWM22527.1 - 4.3 6.3 27.7 5.9 5.9 27.7 1.1 1 0 0 1 1 1 0 Pes-10 TFB6 PF17110.5 EWM22527.1 - 7.6 6.2 13.3 12 5.6 13.3 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH N6-adenineMlase PF10237.9 EWM22528.1 - 0.083 12.7 0.0 0.091 12.6 0.0 1.1 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase DUF563 PF04577.14 EWM22530.1 - 3.7e-22 79.5 0.0 3.1e-16 60.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF563) PAP2_C PF14360.6 EWM22532.1 - 1e-11 45.2 8.0 1e-11 45.2 8.0 2.1 2 0 0 2 2 2 1 PAP2 superfamily C-terminal PAP2 PF01569.21 EWM22532.1 - 0.0052 16.5 2.5 0.0052 16.5 2.5 2.2 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 EWM22532.1 - 0.013 15.2 13.5 0.034 13.8 13.5 1.7 1 0 0 1 1 1 0 PAP2 superfamily CPP1-like PF11833.8 EWM22532.1 - 1.7 8.2 4.4 0.43 10.2 1.1 1.6 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Metallophos PF00149.28 EWM22533.1 - 1.1e-14 55.4 0.1 1.4e-14 55.1 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Thioredoxin_8 PF13905.6 EWM22534.1 - 5.7e-14 52.2 0.0 9.1e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EWM22534.1 - 2.1e-06 27.6 0.0 4.7e-06 26.5 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 EWM22534.1 - 0.00017 21.3 0.0 0.00026 20.7 0.0 1.2 1 0 0 1 1 1 1 Redoxin BSD PF03909.17 EWM22539.1 - 6.4e-11 42.1 1.3 2.5e-07 30.6 0.5 2.2 2 0 0 2 2 2 2 BSD domain SHOCT PF09851.9 EWM22539.1 - 0.029 14.1 0.1 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 Short C-terminal domain UFD1 PF03152.14 EWM22540.1 - 2.8e-05 23.7 0.1 3.9e-05 23.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Peptidase_M32 PF02074.15 EWM22541.1 - 8.1e-154 513.0 0.0 1.3e-153 512.3 0.0 1.3 1 1 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase UFD1 PF03152.14 EWM22542.1 - 2.2e-32 111.9 0.0 2.5e-32 111.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Utp11 PF03998.13 EWM22544.1 - 5.1e-50 170.7 7.0 6.3e-50 170.4 7.0 1.0 1 0 0 1 1 1 1 Utp11 protein Metallophos_3 PF14582.6 EWM22545.1 - 0.0023 17.3 0.0 0.0042 16.4 0.0 1.3 1 0 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily Exo_endo_phos PF03372.23 EWM22546.1 - 0.069 12.6 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family TPR_2 PF07719.17 EWM22548.1 - 8.2e-07 28.7 0.0 0.22 11.7 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EWM22548.1 - 0.00056 20.2 0.4 2.8 8.3 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EWM22548.1 - 0.0019 18.7 0.0 20 6.1 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 EWM22548.1 - 0.0019 18.3 0.2 0.17 12.0 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat HemY_N PF07219.13 EWM22548.1 - 0.0028 17.8 0.6 0.0059 16.8 0.2 1.7 2 0 0 2 2 2 1 HemY protein N-terminus TPR_16 PF13432.6 EWM22548.1 - 0.0042 17.7 0.1 2.1 9.1 0.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EWM22548.1 - 0.011 15.4 0.4 0.52 10.0 0.1 2.4 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_7 PF13176.6 EWM22548.1 - 0.023 14.7 0.0 58 4.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EWM22548.1 - 0.033 14.1 1.5 32 4.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 EWM22548.1 - 0.053 14.2 0.9 93 4.1 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EWM22548.1 - 0.15 11.9 0.0 40 4.3 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EWM22548.1 - 0.19 12.0 0.0 88 3.7 0.0 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat WD40 PF00400.32 EWM22550.1 - 1.4e-30 104.8 6.5 2.1e-06 28.4 0.1 9.2 9 1 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM22550.1 - 1.2e-17 64.0 0.0 0.00017 21.8 0.0 6.0 2 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EWM22550.1 - 2.7e-05 24.0 0.0 3.6 7.6 0.0 4.3 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 EWM22550.1 - 0.00047 20.1 0.0 0.11 12.4 0.0 3.6 4 1 1 5 5 5 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EWM22550.1 - 0.0038 16.2 0.1 0.2 10.6 0.0 3.1 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EWM22550.1 - 0.0062 15.9 0.0 0.046 13.1 0.0 2.3 3 0 0 3 3 3 1 WD40-like domain Kelch_6 PF13964.6 EWM22550.1 - 0.057 13.7 0.2 70 3.9 0.1 4.0 3 0 0 3 3 3 0 Kelch motif Proteasome_A_N PF10584.9 EWM22550.1 - 0.065 12.9 1.7 43 3.9 0.0 4.0 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature DUF1513 PF07433.11 EWM22550.1 - 0.068 12.2 0.2 0.75 8.8 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1513) MMS19_C PF12460.8 EWM22552.1 - 0.48 9.5 1.1 0.75 8.8 1.1 1.2 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal Utp12 PF04003.12 EWM22553.1 - 5.1e-11 42.8 0.9 7.3e-11 42.3 0.9 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 EWM22553.1 - 1.3e-05 25.4 0.0 0.11 12.8 0.0 2.7 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EWM22553.1 - 0.054 14.4 0.1 74 4.5 0.0 3.5 3 0 0 3 3 3 0 WD domain, G-beta repeat DUF640 PF04852.12 EWM22554.1 - 0.11 12.7 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF640) Pkinase PF00069.25 EWM22555.1 - 1.3e-68 231.2 0.0 1.5e-68 231.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM22555.1 - 1.1e-39 136.4 0.0 1.3e-39 136.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EWM22555.1 - 5.9e-12 45.5 0.0 5.7e-09 35.7 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.23 EWM22555.1 - 0.0027 17.6 1.6 0.0046 16.9 1.2 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Abp2 PF09441.10 EWM22555.1 - 0.03 14.4 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 ARS binding protein 2 PAZ PF02170.22 EWM22555.1 - 0.069 13.0 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 PAZ domain DUF599 PF04654.12 EWM22556.1 - 1.6e-18 66.9 3.7 2.3e-18 66.4 3.7 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF599 Trypsin_2 PF13365.6 EWM22557.1 - 2.4e-06 28.5 0.0 4.5e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 EWM22557.1 - 1.7e-05 24.7 0.0 2.7e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 Trypsin SmaI PF17411.2 EWM22557.1 - 0.22 10.6 0.0 0.37 9.9 0.0 1.3 1 0 0 1 1 1 0 Type II site-specific deoxyribonuclease DNA_pol_phi PF04931.13 EWM22558.1 - 3.9e-05 22.0 9.1 4.5e-05 21.8 9.1 1.1 1 0 0 1 1 1 1 DNA polymerase phi PPP4R2 PF09184.11 EWM22558.1 - 0.00029 20.5 5.1 0.00033 20.3 5.1 1.2 1 0 0 1 1 1 1 PPP4R2 DUF2052 PF09747.9 EWM22558.1 - 0.00045 20.4 7.6 0.00063 19.9 7.6 1.3 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) MecA PF05389.12 EWM22558.1 - 0.0016 18.1 1.5 0.0021 17.7 1.5 1.1 1 0 0 1 1 1 1 Negative regulator of genetic competence (MecA) DUF719 PF05334.13 EWM22558.1 - 0.0027 17.9 0.1 0.0038 17.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF719) BUD22 PF09073.10 EWM22558.1 - 0.0032 16.9 2.7 0.0043 16.5 2.7 1.3 1 0 0 1 1 1 1 BUD22 Paf1 PF03985.13 EWM22558.1 - 0.0042 16.2 15.0 0.0056 15.7 15.0 1.1 1 0 0 1 1 1 1 Paf1 CobT PF06213.12 EWM22558.1 - 0.0052 16.2 8.7 0.0075 15.7 8.7 1.3 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT Sigma70_ner PF04546.13 EWM22558.1 - 0.0055 16.6 9.1 0.0088 15.9 9.1 1.3 1 0 0 1 1 1 1 Sigma-70, non-essential region Radial_spoke PF04712.12 EWM22558.1 - 0.0067 15.4 11.4 0.009 15.0 11.4 1.1 1 0 0 1 1 1 1 Radial spokehead-like protein FancD2 PF14631.6 EWM22558.1 - 0.011 13.2 5.4 0.015 12.8 5.4 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease PI3K_1B_p101 PF10486.9 EWM22558.1 - 0.013 13.3 2.6 0.015 13.1 2.6 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Connexin PF00029.19 EWM22558.1 - 0.015 15.1 0.6 0.02 14.7 0.6 1.2 1 0 0 1 1 1 0 Connexin Mpp10 PF04006.12 EWM22558.1 - 0.015 13.7 13.0 0.021 13.3 13.0 1.1 1 0 0 1 1 1 0 Mpp10 protein FAM176 PF14851.6 EWM22558.1 - 0.019 14.6 5.5 0.035 13.7 5.5 1.4 1 0 0 1 1 1 0 FAM176 family RXT2_N PF08595.11 EWM22558.1 - 0.024 14.6 4.5 0.037 14.1 4.5 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal CPSF100_C PF13299.6 EWM22558.1 - 0.027 14.6 0.3 0.046 13.9 0.3 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Hus1 PF04005.12 EWM22558.1 - 0.031 13.4 0.2 0.055 12.6 0.2 1.3 1 0 0 1 1 1 0 Hus1-like protein RPN2_C PF18004.1 EWM22558.1 - 0.034 14.1 5.2 0.064 13.2 5.2 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Cytomega_UL84 PF06284.11 EWM22558.1 - 0.046 12.2 1.4 0.059 11.8 1.4 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein POX PF07526.11 EWM22558.1 - 0.062 13.9 0.2 0.5 10.9 0.8 1.9 2 0 0 2 2 2 0 Associated with HOX DUF4770 PF15994.5 EWM22558.1 - 0.079 13.2 0.3 0.14 12.4 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DUF4611 PF15387.6 EWM22558.1 - 0.13 12.5 13.0 0.26 11.5 13.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Tim54 PF11711.8 EWM22558.1 - 0.17 10.6 3.6 0.25 10.1 3.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Presenilin PF01080.17 EWM22558.1 - 0.18 10.5 1.0 0.23 10.2 1.0 1.1 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 EWM22558.1 - 0.19 9.6 2.4 0.23 9.4 2.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RRN3 PF05327.11 EWM22558.1 - 0.19 10.2 5.4 0.27 9.7 5.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CENP-B_dimeris PF09026.10 EWM22558.1 - 0.26 11.7 14.4 0.67 10.4 14.4 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Fmp27 PF10344.9 EWM22558.1 - 0.67 8.0 3.0 0.85 7.6 3.0 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 TFB6 PF17110.5 EWM22558.1 - 0.7 9.6 6.0 1 9.1 6.0 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF1682 PF07946.14 EWM22558.1 - 0.92 8.7 9.8 1.4 8.1 9.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF1840 PF08895.11 EWM22558.1 - 1.2 9.5 7.0 2.5 8.5 7.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) PTPRCAP PF15713.5 EWM22558.1 - 1.4 9.2 15.8 2.5 8.4 15.8 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Nop53 PF07767.11 EWM22558.1 - 2.5 7.4 17.5 4.3 6.6 17.5 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF4746 PF15928.5 EWM22558.1 - 2.5 7.5 17.7 3.7 6.9 17.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) GNAT_acetyltr_2 PF13718.6 EWM22558.1 - 2.6 7.4 4.6 4 6.8 4.6 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 RED_N PF07808.13 EWM22558.1 - 2.6 7.6 9.8 4 7.0 9.8 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region SDA1 PF05285.12 EWM22558.1 - 2.6 7.4 17.7 3.9 6.8 17.7 1.1 1 0 0 1 1 1 0 SDA1 AAA_23 PF13476.6 EWM22558.1 - 3.2 8.2 10.5 4.6 7.7 10.5 1.1 1 0 0 1 1 1 0 AAA domain GCIP PF13324.6 EWM22558.1 - 3.4 7.2 6.9 4.9 6.7 6.9 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Nop14 PF04147.12 EWM22558.1 - 4.7 5.3 19.8 6.8 4.8 19.8 1.1 1 0 0 1 1 1 0 Nop14-like family BSP_II PF05432.11 EWM22558.1 - 8.7 5.9 23.6 13 5.3 23.6 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Lipase_3 PF01764.25 EWM22561.1 - 8.4e-24 84.1 0.0 1.5e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) C2 PF00168.30 EWM22561.1 - 3.8e-07 30.3 0.0 6.2e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 C2 domain DUF2974 PF11187.8 EWM22561.1 - 0.0082 15.7 0.0 4.5 6.8 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 EWM22561.1 - 0.064 13.8 0.0 0.064 13.8 0.0 2.2 2 1 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EWM22561.1 - 0.087 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EWM22561.1 - 0.14 11.4 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 EWM22562.1 - 1e-14 54.6 0.0 1.7e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) C2 PF00168.30 EWM22562.1 - 3.7e-07 30.4 0.0 5.8e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 C2 domain DUF2974 PF11187.8 EWM22562.1 - 0.0079 15.8 0.0 4.5 6.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 EWM22562.1 - 0.11 13.1 0.0 0.11 13.1 0.0 2.3 2 1 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EWM22562.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EWM22562.1 - 0.13 11.5 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 MFS_1 PF07690.16 EWM22563.1 - 1.2e-38 132.9 24.9 1.2e-38 132.9 24.9 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EWM22563.1 - 4.4e-08 32.4 11.7 1.1e-07 31.1 1.0 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.20 EWM22563.1 - 0.17 10.2 3.4 0.14 10.4 0.2 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 EWM22563.1 - 6 5.6 11.3 0.97 8.2 0.8 3.0 1 1 2 3 3 3 0 MFS_1 like family Mito_fiss_reg PF05308.11 EWM22564.1 - 0.0009 19.4 2.2 0.0012 18.9 2.2 1.1 1 0 0 1 1 1 1 Mitochondrial fission regulator PepSY_TM PF03929.16 EWM22564.1 - 0.19 11.4 0.4 0.85 9.2 0.3 1.8 2 0 0 2 2 2 0 PepSY-associated TM region EMC3_TMCO1 PF01956.16 EWM22564.1 - 0.26 11.0 2.5 0.37 10.5 2.5 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like ROK PF00480.20 EWM22566.1 - 5.7e-15 55.6 0.0 6.6e-15 55.4 0.0 1.0 1 0 0 1 1 1 1 ROK family UVR PF02151.19 EWM22575.1 - 0.013 15.2 1.6 0.028 14.2 1.6 1.6 1 0 0 1 1 1 0 UvrB/uvrC motif Vpu PF00558.19 EWM22575.1 - 0.37 10.6 0.1 0.37 10.6 0.1 2.7 4 0 0 4 4 4 0 Vpu protein Tic110 PF16940.5 EWM22576.1 - 2e-15 56.3 0.6 4.6e-05 22.1 0.0 3.1 1 1 2 3 3 3 3 Chloroplast envelope transporter EF-hand_6 PF13405.6 EWM22577.1 - 0.0043 16.9 0.2 0.011 15.6 0.0 1.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 EWM22577.1 - 0.0073 16.7 0.0 0.02 15.3 0.0 1.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EWM22577.1 - 0.018 14.6 0.7 0.051 13.1 0.0 1.9 2 0 0 2 2 2 0 EF hand DUF572 PF04502.13 EWM22578.1 - 6.4e-60 203.5 10.6 7.5e-60 203.3 10.6 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF866 PF05907.13 EWM22578.1 - 0.0019 18.2 1.5 0.0024 17.8 1.5 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) DUF2989 PF11207.8 EWM22578.1 - 0.041 13.6 0.5 0.08 12.7 0.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2989) DUF5352 PF17303.2 EWM22578.1 - 0.061 13.2 0.2 0.078 12.8 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5352) Aldolase_II PF00596.21 EWM22579.1 - 4.2e-42 144.2 0.0 8.6e-42 143.2 0.0 1.5 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain ARD PF03079.14 EWM22579.1 - 0.00091 19.4 0.0 0.0015 18.7 0.0 1.3 1 0 0 1 1 1 1 ARD/ARD' family Ribosomal_S28e PF01200.18 EWM22580.1 - 1.1e-05 25.3 0.4 1.8e-05 24.6 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S28e Trp_syntA PF00290.20 EWM22581.1 - 5.7e-82 274.5 0.0 7.7e-82 274.0 0.0 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 EWM22581.1 - 5.9e-46 157.2 2.5 1e-45 156.4 2.5 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PcrB PF01884.17 EWM22581.1 - 0.017 14.6 0.1 0.045 13.2 0.1 1.6 1 0 0 1 1 1 0 PcrB family His_biosynth PF00977.21 EWM22581.1 - 0.038 13.5 0.0 0.081 12.4 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein Ion_trans_2 PF07885.16 EWM22582.1 - 8.4e-08 32.1 8.1 1.8e-07 31.0 8.1 1.5 1 0 0 1 1 1 1 Ion channel Meckelin PF09773.9 EWM22582.1 - 0.64 8.0 2.2 1 7.4 2.2 1.2 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) Alph_Pro_TM PF09608.10 EWM22583.1 - 0.024 14.5 0.1 0.03 14.2 0.1 1.2 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) TFIID-18kDa PF02269.16 EWM22584.1 - 8.4e-26 89.8 0.7 1e-25 89.5 0.7 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 EWM22584.1 - 0.021 14.8 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Band_3_cyto PF07565.13 EWM22587.1 - 2.2 8.0 9.7 0.34 10.7 3.5 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain PI3_PI4_kinase PF00454.27 EWM22588.1 - 2.1e-15 57.3 0.0 5.7e-12 46.0 0.0 2.9 2 1 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase GIDA PF01134.22 EWM22590.1 - 4.5e-141 470.5 0.0 5.6e-141 470.2 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 EWM22590.1 - 5.5e-62 209.7 0.0 8.1e-62 209.1 0.0 1.3 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 EWM22590.1 - 2.2e-06 27.3 3.8 3.4e-06 26.7 3.8 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EWM22590.1 - 3.5e-05 23.2 2.7 6.2e-05 22.4 2.0 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EWM22590.1 - 3.6e-05 23.0 2.5 3.6e-05 23.0 2.5 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 EWM22590.1 - 0.0026 17.1 0.2 0.029 13.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EWM22590.1 - 0.0039 17.7 0.3 0.012 16.2 0.3 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EWM22590.1 - 0.0066 15.2 3.5 0.058 12.1 0.6 2.6 3 0 0 3 3 3 1 HI0933-like protein AlaDh_PNT_C PF01262.21 EWM22590.1 - 0.0072 15.6 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 EWM22590.1 - 0.014 14.4 2.1 0.049 12.7 2.1 1.9 1 1 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 EWM22590.1 - 0.015 15.5 0.7 0.12 12.6 1.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EWM22590.1 - 0.021 14.1 1.5 0.13 11.5 1.6 2.0 1 1 0 1 1 1 0 Thi4 family DAO PF01266.24 EWM22590.1 - 0.028 14.0 3.3 0.94 9.0 0.3 2.6 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EWM22590.1 - 0.041 13.1 0.4 0.077 12.2 0.4 1.4 1 0 0 1 1 1 0 FAD binding domain Bactofilin PF04519.13 EWM22591.1 - 2.1e-06 27.9 14.1 0.027 14.8 5.4 4.6 4 1 1 5 5 5 3 Polymer-forming cytoskeletal DUF3713 PF12506.8 EWM22592.1 - 0.19 12.0 0.5 0.55 10.6 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3713) DUF4097 PF13349.6 EWM22592.1 - 0.89 8.8 10.5 8.1 5.7 10.5 2.1 1 1 0 1 1 1 0 Putative adhesin GST_N_2 PF13409.6 EWM22594.1 - 1.7e-16 60.3 0.1 6.3e-16 58.4 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EWM22594.1 - 1.7e-12 47.2 0.0 4.4e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EWM22594.1 - 3.4e-06 27.4 0.0 0.031 14.7 0.1 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EWM22594.1 - 2.8e-05 24.2 0.0 5.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EWM22594.1 - 4e-05 23.7 0.0 6.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EWM22594.1 - 7.1e-05 22.5 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Acetyltransf_1 PF00583.25 EWM22595.1 - 1.2e-13 51.3 0.0 3.5e-13 49.8 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EWM22595.1 - 3e-10 40.4 0.0 7.5e-10 39.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EWM22595.1 - 1.3e-07 31.6 0.0 2.6e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EWM22595.1 - 7.6e-07 29.0 0.0 1.8e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 EWM22595.1 - 0.00082 19.1 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EWM22595.1 - 0.0052 16.9 0.0 0.0079 16.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EWM22595.1 - 0.0056 16.8 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 EWM22595.1 - 0.0094 15.4 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_9 PF13527.7 EWM22595.1 - 0.013 15.6 0.2 0.045 13.8 0.2 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EWM22595.1 - 0.023 15.4 0.0 0.031 14.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 EWM22595.1 - 0.084 12.6 0.0 0.18 11.6 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain, PanZ zf-RING_2 PF13639.6 EWM22596.1 - 9.7e-09 35.4 7.4 1.6e-08 34.7 7.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EWM22596.1 - 5.1e-06 26.2 7.1 9e-06 25.4 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EWM22596.1 - 3.3e-05 23.5 3.5 6.1e-05 22.7 3.5 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EWM22596.1 - 0.00011 22.1 4.0 0.00012 22.1 2.6 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EWM22596.1 - 0.00033 20.6 5.9 0.00058 19.8 5.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EWM22596.1 - 0.00096 19.0 7.5 0.0015 18.3 7.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Dynactin_p62 PF05502.13 EWM22596.1 - 0.0012 17.7 0.1 0.0016 17.3 0.1 1.1 1 0 0 1 1 1 1 Dynactin p62 family zf-C3HC4_3 PF13920.6 EWM22596.1 - 0.0013 18.5 5.0 0.0021 17.8 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EWM22596.1 - 0.022 15.0 7.6 0.049 13.9 7.6 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EWM22596.1 - 0.047 13.7 4.7 0.084 12.9 4.7 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 EWM22596.1 - 0.051 13.4 3.6 0.1 12.4 3.6 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 EWM22596.1 - 0.25 11.0 6.1 0.4 10.3 5.5 1.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 EWM22596.1 - 0.85 9.8 9.2 14 5.9 9.2 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 EWM22596.1 - 1.1 9.1 3.7 2.5 7.9 3.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Aa_trans PF01490.18 EWM22597.1 - 1.1e-43 149.4 21.3 1.4e-43 149.1 21.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EWM22597.1 - 1.3e-05 24.5 8.8 1.3e-05 24.5 8.8 2.3 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family VioE PF18234.1 EWM22600.1 - 0.041 14.0 0.0 0.064 13.4 0.0 1.3 1 0 0 1 1 1 0 Violacein biosynthetic enzyme VioE Ribosomal_L27e PF01777.18 EWM22601.1 - 5.5e-23 81.1 5.3 8.6e-23 80.5 5.3 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 EWM22601.1 - 3.3e-06 26.9 1.5 3.3e-06 26.9 1.5 2.1 2 0 0 2 2 2 1 KOW motif Myb_DNA-binding PF00249.31 EWM22603.1 - 2.1e-13 50.2 0.2 2.7e-13 49.9 0.2 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EWM22603.1 - 1.5e-05 24.8 0.0 1.9e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 EWM22603.1 - 9.8e-05 22.5 0.1 0.00012 22.3 0.1 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain adh_short_C2 PF13561.6 EWM22604.1 - 6.1e-56 189.6 6.4 8e-56 189.2 6.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EWM22604.1 - 6.8e-47 159.4 3.0 6.8e-47 159.4 3.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EWM22604.1 - 2e-10 40.9 4.4 1.2e-09 38.4 4.4 1.9 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EWM22604.1 - 6.9e-06 25.4 0.3 1.1e-05 24.8 0.3 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 EWM22604.1 - 0.0022 17.9 0.6 0.0042 17.0 0.6 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 EWM22604.1 - 0.0024 17.4 0.2 0.0035 16.8 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 EWM22604.1 - 0.028 13.8 0.2 0.057 12.8 0.2 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EWM22604.1 - 0.036 14.3 0.4 0.083 13.1 0.4 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 EWM22604.1 - 0.083 13.3 1.4 0.16 12.4 1.4 1.5 1 1 0 1 1 1 0 Putative NAD(P)-binding AdoHcyase_NAD PF00670.21 EWM22604.1 - 0.63 10.1 4.3 2.3 8.3 1.6 2.5 2 1 1 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Mito_carr PF00153.27 EWM22605.1 - 1.6e-54 181.8 0.0 1.6e-19 69.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Prenyltrans PF00432.21 EWM22605.1 - 0.77 9.6 4.6 0.39 10.5 0.1 2.6 3 0 0 3 3 3 0 Prenyltransferase and squalene oxidase repeat GTP_EFTU PF00009.27 EWM22606.1 - 1.5e-06 27.9 0.0 0.024 14.2 0.1 3.1 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EWM22606.1 - 0.0034 17.7 0.2 0.016 15.5 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain RsgA_GTPase PF03193.16 EWM22606.1 - 0.21 11.5 0.5 19 5.1 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase START PF01852.19 EWM22607.1 - 5.5e-07 29.2 0.1 8.2e-07 28.6 0.1 1.2 1 0 0 1 1 1 1 START domain Aminotran_1_2 PF00155.21 EWM22608.1 - 1.8e-33 116.2 0.0 2.1e-33 116.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EWM22608.1 - 0.053 12.5 0.0 0.076 12.0 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EWM22608.1 - 0.059 12.7 0.0 0.088 12.1 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family FAD_binding_4 PF01565.23 EWM22609.1 - 5e-29 100.8 0.5 9.9e-29 99.9 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 EWM22609.1 - 4.1e-26 92.3 0.0 3.1e-20 73.1 0.1 2.2 2 0 0 2 2 2 2 D-arabinono-1,4-lactone oxidase Surp PF01805.20 EWM22609.1 - 0.073 13.1 0.2 0.16 12.0 0.2 1.6 1 0 0 1 1 1 0 Surp module Bax1-I PF01027.20 EWM22610.1 - 1.4e-40 139.3 19.7 2.2e-40 138.7 19.7 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2721 PF11026.8 EWM22610.1 - 1.6 8.7 8.1 3.8 7.4 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) PMSR PF01625.21 EWM22611.1 - 2.9e-55 186.6 0.9 4.5e-55 186.0 0.9 1.2 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase DUF5633 PF18656.1 EWM22611.1 - 0.0092 15.9 0.4 0.043 13.7 0.0 2.1 2 0 0 2 2 2 1 Family of unknown function (DUF5633) Aa_trans PF01490.18 EWM22612.1 - 7.7e-41 140.1 32.7 1.4e-40 139.3 31.5 1.8 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3713 PF12506.8 EWM22613.1 - 0.022 15.1 2.9 2.1 8.6 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3713) Methyltransf_31 PF13847.6 EWM22616.1 - 1.4e-06 28.2 0.1 2.7e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM22616.1 - 1.4e-06 28.9 0.1 4.1e-06 27.4 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 EWM22616.1 - 1.8e-05 24.3 0.0 2.9e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_11 PF08241.12 EWM22616.1 - 0.00013 22.5 0.2 0.0003 21.4 0.2 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EWM22616.1 - 0.00062 19.6 0.0 0.00072 19.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EWM22616.1 - 0.00085 18.8 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 EWM22616.1 - 0.00094 19.9 0.0 0.0016 19.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EWM22616.1 - 0.0012 18.2 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 EWM22616.1 - 0.0061 16.2 0.1 0.0089 15.6 0.1 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 EWM22616.1 - 0.01 15.4 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 EWM22616.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase CtaG_Cox11 PF04442.14 EWM22617.1 - 5.2e-61 205.1 0.3 6.8e-61 204.7 0.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 EAP30 PF04157.16 EWM22618.1 - 2.4e-67 226.7 0.6 2.8e-67 226.4 0.6 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family IZUMO PF15005.6 EWM22618.1 - 0.057 13.9 1.4 0.77 10.3 0.1 2.1 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated DUF4423 PF14394.6 EWM22618.1 - 0.067 12.9 0.5 1.9 8.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) Methyltransf_16 PF10294.9 EWM22619.1 - 1.9e-18 66.8 0.0 2.8e-09 37.0 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 EWM22619.1 - 0.00088 19.1 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EWM22619.1 - 0.0033 17.0 0.0 0.016 14.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 EWM22619.1 - 0.048 13.1 0.1 0.085 12.2 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 EWM22619.1 - 0.24 11.1 0.2 1.2 8.8 0.1 1.9 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) His_Phos_2 PF00328.22 EWM22620.1 - 2.5e-10 40.2 0.3 1.4e-09 37.8 0.3 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) CRAL_TRIO PF00650.20 EWM22622.1 - 1.7e-24 86.4 0.0 2.1e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain PhoLip_ATPase_C PF16212.5 EWM22623.1 - 1.6e-62 211.5 30.7 1.6e-62 211.5 30.7 2.4 2 1 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EWM22623.1 - 4.6e-21 74.3 0.1 4.6e-21 74.3 0.1 2.2 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EWM22623.1 - 2.6e-10 40.2 0.0 2.2e-09 37.3 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EWM22623.1 - 1.2e-07 32.3 1.8 0.0047 17.2 0.8 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EWM22623.1 - 2.2e-06 27.3 0.0 2.2e-06 27.3 0.0 3.3 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EWM22623.1 - 0.016 15.0 0.1 0.037 13.8 0.1 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase tRNA-synt_1c PF00749.21 EWM22624.1 - 0.015 14.2 1.4 0.02 13.8 1.4 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain Beta_elim_lyase PF01212.21 EWM22625.1 - 2.3e-86 289.7 0.0 4.4e-86 288.8 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EWM22625.1 - 3.1e-06 26.8 0.0 0.00034 20.0 0.0 2.3 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family ERG4_ERG24 PF01222.17 EWM22626.1 - 1.8e-65 221.4 11.7 2.1e-65 221.2 11.7 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family TPR_2 PF07719.17 EWM22628.1 - 8.8e-17 59.8 7.5 0.0011 18.9 0.0 8.6 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_1 PF00515.28 EWM22628.1 - 7.5e-14 50.9 1.9 0.00087 19.0 0.0 7.5 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 EWM22628.1 - 4.9e-13 48.2 0.2 0.015 15.5 0.0 6.5 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 EWM22628.1 - 1.4e-12 47.3 15.4 0.014 16.2 0.1 7.1 5 1 4 9 9 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 EWM22628.1 - 1.2e-11 44.9 8.2 0.0011 19.4 0.2 6.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 EWM22628.1 - 5e-10 39.9 21.4 0.00095 19.8 0.6 7.9 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 EWM22628.1 - 1.1e-07 31.9 1.9 0.35 11.0 0.0 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EWM22628.1 - 7.8e-07 28.7 0.1 0.066 12.9 0.0 4.0 4 0 0 4 4 4 2 TPR repeat TPR_17 PF13431.6 EWM22628.1 - 1.2e-06 28.4 1.1 2 9.0 0.0 5.4 5 0 0 5 5 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EWM22628.1 - 1.1e-05 25.6 9.1 0.013 15.7 0.2 5.4 5 2 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EWM22628.1 - 1.7e-05 25.0 19.3 0.13 12.5 0.3 7.0 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_21 PF09976.9 EWM22628.1 - 5.8e-05 22.9 2.1 0.76 9.5 0.1 4.2 3 1 0 4 4 4 2 Tetratricopeptide repeat-like domain TPR_7 PF13176.6 EWM22628.1 - 0.0014 18.5 3.3 14 5.9 0.0 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 EWM22628.1 - 0.0015 19.0 10.5 83 4.1 0.0 7.6 9 0 0 9 9 8 0 Tetratricopeptide repeat VHP PF02209.19 EWM22628.1 - 0.016 15.2 0.0 0.049 13.7 0.0 1.8 2 0 0 2 2 2 0 Villin headpiece domain TPR_20 PF14561.6 EWM22628.1 - 0.17 12.3 3.1 0.39 11.1 0.1 3.1 3 1 1 4 4 4 0 Tetratricopeptide repeat ADH_zinc_N PF00107.26 EWM22629.1 - 3.1e-07 30.4 0.3 2.5e-06 27.5 0.1 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EWM22629.1 - 0.0067 17.5 0.0 0.037 15.1 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase XdhC_C PF13478.6 EWM22629.1 - 0.01 16.3 0.1 0.02 15.4 0.1 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain Glyco_transf_20 PF00982.21 EWM22631.1 - 7.8e-103 344.7 0.0 7e-102 341.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EWM22631.1 - 6.6e-32 110.5 0.0 2.3e-31 108.7 0.0 1.9 2 0 0 2 2 2 1 Trehalose-phosphatase S6PP PF05116.13 EWM22631.1 - 0.00084 18.9 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.12 EWM22631.1 - 0.0071 16.1 0.0 0.023 14.4 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase His_Phos_2 PF00328.22 EWM22632.1 - 1.2e-21 77.5 0.0 1.4e-12 47.7 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Trehalase PF01204.18 EWM22633.1 - 5e-131 438.0 0.0 6.2e-131 437.7 0.0 1.1 1 0 0 1 1 1 1 Trehalase Phos_pyr_kin PF08543.12 EWM22634.1 - 3.9e-17 62.4 0.0 6.1e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EWM22634.1 - 2.1e-10 40.4 0.1 1e-09 38.1 0.0 2.0 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Hydrolase PF00702.26 EWM22634.1 - 4.5e-08 33.6 0.3 0.00033 21.0 0.0 2.9 2 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EWM22634.1 - 0.0096 16.3 0.1 0.3 11.5 0.1 2.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EWM22634.1 - 0.0098 16.0 0.0 4.8 7.2 0.0 3.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Carb_kinase PF01256.17 EWM22634.1 - 0.052 13.0 0.0 0.22 10.9 0.0 1.9 2 0 0 2 2 2 0 Carbohydrate kinase Ribosomal_S19 PF00203.21 EWM22635.1 - 1.1e-27 95.6 0.2 1.8e-27 95.0 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 zf-UBR PF02207.20 EWM22636.1 - 2.4e-15 56.4 18.0 4.8e-15 55.5 18.0 1.5 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 EWM22636.1 - 2.1e-05 24.2 0.0 4.8e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-CXXC PF02008.20 EWM22636.1 - 0.11 12.6 5.5 0.29 11.2 5.5 1.7 1 0 0 1 1 1 0 CXXC zinc finger domain CRAL_TRIO PF00650.20 EWM22637.1 - 2.9e-21 75.8 0.0 4.6e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CPL PF08144.11 EWM22638.1 - 6.1e-08 33.1 0.3 0.00025 21.4 0.0 3.2 3 0 0 3 3 3 2 CPL (NUC119) domain AMP-binding_C PF13193.6 EWM22638.1 - 0.013 16.4 0.1 0.49 11.4 0.0 2.7 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain PUF PF00806.19 EWM22638.1 - 0.056 13.2 0.0 4.8 7.1 0.0 3.0 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat RF-1 PF00472.20 EWM22640.1 - 7.5e-22 77.5 1.4 1.1e-21 76.9 1.4 1.1 1 0 0 1 1 1 1 RF-1 domain CorA PF01544.18 EWM22642.1 - 0.0012 18.3 1.5 0.0012 18.3 1.5 2.1 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein V_ATPase_I PF01496.19 EWM22642.1 - 0.0066 14.4 6.8 0.0078 14.2 6.8 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DDHD PF02862.17 EWM22642.1 - 0.0084 16.3 2.4 0.0099 16.1 2.4 1.1 1 0 0 1 1 1 1 DDHD domain DUF2207 PF09972.9 EWM22642.1 - 0.012 14.4 2.9 0.014 14.2 2.0 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF702 PF05142.12 EWM22642.1 - 0.62 10.5 5.8 0.96 9.9 5.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF702) DUF4407 PF14362.6 EWM22642.1 - 1.4 8.2 6.2 2.9 7.1 6.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YabA PF06156.13 EWM22642.1 - 1.7 9.3 17.3 0.078 13.6 11.1 1.9 3 0 0 3 3 3 0 Initiation control protein YabA Spt20 PF12090.8 EWM22642.1 - 1.9 8.1 15.9 2.7 7.5 15.9 1.3 1 0 0 1 1 1 0 Spt20 family zf-CW PF07496.15 EWM22643.1 - 1.6e-05 24.8 0.6 3.2e-05 23.8 0.6 1.5 1 0 0 1 1 1 1 CW-type Zinc Finger DUF35_N PF12172.8 EWM22643.1 - 0.1 12.5 0.1 0.1 12.5 0.1 1.9 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) PRIMA1 PF16101.5 EWM22643.1 - 3.7 7.6 8.5 6.7 6.8 8.5 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 NAD_binding_8 PF13450.6 EWM22644.1 - 4.6e-11 42.8 0.5 9.9e-11 41.7 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EWM22644.1 - 3.3e-07 29.8 0.8 2e-06 27.2 0.1 2.0 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.24 EWM22644.1 - 3.8e-07 29.8 1.0 1.7e-06 27.6 1.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 EWM22644.1 - 1.1e-06 28.3 0.2 1.8e-06 27.6 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 EWM22644.1 - 6e-06 26.1 9.2 8.2e-05 22.3 9.2 2.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EWM22644.1 - 2e-05 24.0 0.3 4.4e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EWM22644.1 - 3.7e-05 23.1 0.2 6.2e-05 22.4 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 EWM22644.1 - 6.1e-05 22.3 2.6 6.1e-05 22.3 2.6 2.2 2 1 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 EWM22644.1 - 0.00028 21.4 2.1 0.013 16.0 0.8 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EWM22644.1 - 0.00075 18.3 0.3 0.0012 17.7 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 EWM22644.1 - 0.0016 17.6 1.5 0.0027 16.8 1.5 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A GMC_oxred_N PF00732.19 EWM22644.1 - 0.0025 17.2 0.6 0.021 14.2 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase Trp_halogenase PF04820.14 EWM22644.1 - 0.012 14.5 0.5 0.012 14.5 0.5 1.7 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 EWM22644.1 - 0.012 14.8 0.7 0.018 14.3 0.7 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 EWM22644.1 - 0.031 13.6 0.2 1.2 8.4 0.1 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MCRA PF06100.11 EWM22644.1 - 0.052 12.3 0.2 0.075 11.8 0.2 1.2 1 0 0 1 1 1 0 MCRA family YjeF_N PF03853.15 EWM22644.1 - 0.062 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 YjeF-related protein N-terminus Lycopene_cycl PF05834.12 EWM22644.1 - 0.13 11.3 1.1 0.62 9.0 0.8 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Proteasome PF00227.26 EWM22645.1 - 7.9e-27 94.0 0.0 1e-26 93.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Aldose_epim PF01263.20 EWM22646.1 - 2.1e-37 129.1 0.1 3.4e-37 128.4 0.1 1.3 1 1 0 1 1 1 1 Aldose 1-epimerase Hamartin PF04388.12 EWM22647.1 - 4.1 6.0 13.0 5.4 5.5 13.0 1.2 1 0 0 1 1 1 0 Hamartin protein Proteasome PF00227.26 EWM22648.1 - 1.1e-49 168.6 0.3 1.3e-49 168.3 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit PH_3 PF14593.6 EWM22648.1 - 0.21 11.7 0.0 0.39 10.8 0.0 1.3 1 0 0 1 1 1 0 PH domain RRM_1 PF00076.22 EWM22649.1 - 4.4e-20 71.3 0.0 9.1e-20 70.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 EWM22649.1 - 7.8e-13 48.9 2.6 9.9e-13 48.5 1.3 1.8 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal MetallophosC PF16370.5 EWM22649.1 - 0.041 14.1 0.1 0.1 12.8 0.0 1.6 1 1 0 1 1 1 0 C terminal of Calcineurin-like phosphoesterase RRM_8 PF11835.8 EWM22649.1 - 0.26 11.5 0.0 0.49 10.6 0.0 1.5 1 0 0 1 1 1 0 RRM-like domain COG6 PF06419.11 EWM22650.1 - 2.2e-111 373.1 0.0 2.5e-111 372.9 0.0 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 GAS PF13851.6 EWM22650.1 - 0.024 14.0 0.1 0.071 12.5 0.1 1.8 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TPR_14 PF13428.6 EWM22650.1 - 0.12 13.3 5.8 3 8.9 0.5 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Hist_deacetyl PF00850.19 EWM22653.1 - 5.4e-45 154.2 0.1 1.2e-44 153.1 0.1 1.5 1 1 0 1 1 1 1 Histone deacetylase domain Trehalase PF01204.18 EWM22654.1 - 6.9e-138 460.6 0.0 8.2e-138 460.4 0.0 1.0 1 0 0 1 1 1 1 Trehalase OTU PF02338.19 EWM22655.1 - 3.3e-08 34.1 0.0 2.5e-07 31.2 0.0 2.2 1 1 0 1 1 1 1 OTU-like cysteine protease MAPEG PF01124.18 EWM22656.1 - 0.0031 17.4 0.1 0.004 17.0 0.1 1.2 1 0 0 1 1 1 1 MAPEG family CWC25 PF12542.8 EWM22657.1 - 6.7e-17 62.3 1.8 6.7e-17 62.3 1.8 4.5 3 1 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 EWM22657.1 - 2.8e-13 49.8 9.5 2.8e-13 49.8 9.5 6.5 5 2 1 6 6 6 1 N-terminal domain of CBF1 interacting co-repressor CIR WD40 PF00400.32 EWM22658.1 - 1.9e-27 94.9 6.5 4.7e-05 24.1 0.1 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM22658.1 - 1e-15 57.8 1.4 3.7e-05 23.9 0.1 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EWM22658.1 - 1.5e-06 28.2 0.1 0.0054 16.6 0.1 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A IPPT PF01715.17 EWM22660.1 - 1.9e-62 211.0 0.0 5.3e-62 209.6 0.0 1.6 2 0 0 2 2 2 1 IPP transferase IPT PF01745.16 EWM22660.1 - 1.4e-05 24.6 0.1 0.00021 20.8 0.0 2.2 2 0 0 2 2 2 1 Isopentenyl transferase AAA_33 PF13671.6 EWM22660.1 - 0.011 15.9 0.4 0.047 13.8 0.0 2.3 2 2 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EWM22660.1 - 0.027 14.9 2.0 0.13 12.7 1.9 2.4 1 1 0 1 1 1 0 AAA ATPase domain DUF2840 PF11000.8 EWM22660.1 - 0.036 13.8 0.3 0.15 11.8 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2840) Mg_chelatase PF01078.21 EWM22660.1 - 0.11 11.8 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zn_clus PF00172.18 EWM22661.1 - 3.3e-08 33.5 11.2 7e-08 32.5 11.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med9 PF07544.13 EWM22661.1 - 0.026 14.6 0.2 0.064 13.4 0.2 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 TB2_DP1_HVA22 PF03134.19 EWM22663.1 - 1.8e-29 101.5 7.8 1.8e-29 101.5 7.8 1.8 2 1 0 2 2 2 1 TB2/DP1, HVA22 family ECF_trnsprt PF12822.7 EWM22663.1 - 0.0036 17.4 0.6 0.0053 16.9 0.6 1.3 1 0 0 1 1 1 1 ECF transporter, substrate-specific component BH3 PF15285.6 EWM22664.1 - 0.093 12.5 1.7 0.55 10.1 0.6 2.5 2 0 0 2 2 2 0 Beclin-1 BH3 domain, Bcl-2-interacting NACHT PF05729.12 EWM22665.1 - 7.6e-06 25.9 0.1 6.4e-05 22.9 0.1 2.2 1 1 0 1 1 1 1 NACHT domain LRR_6 PF13516.6 EWM22665.1 - 3.1e-05 23.7 9.0 0.027 14.5 0.1 6.0 6 0 0 6 6 6 1 Leucine Rich repeat AAA_16 PF13191.6 EWM22665.1 - 3.5e-05 24.3 0.4 0.00011 22.7 0.1 2.0 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 EWM22665.1 - 0.0018 17.5 0.0 0.0067 15.6 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain PBP1_TM PF14812.6 EWM22665.1 - 8.9 6.8 7.2 1.5 9.2 3.0 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LRR_4 PF12799.7 EWM22665.1 - 9 6.9 8.3 72 4.0 0.0 3.7 2 2 3 5 5 5 0 Leucine Rich repeats (2 copies) TCR PF03638.15 EWM22666.1 - 1.3e-24 86.2 50.3 2.8e-12 46.7 21.2 2.6 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain TrmO PF01980.16 EWM22667.1 - 2.4e-39 134.2 0.0 4.8e-39 133.3 0.0 1.5 1 0 0 1 1 1 1 tRNA-methyltransferase O ERM PF00769.19 EWM22668.1 - 0.0003 20.7 11.5 0.0003 20.7 11.5 2.8 2 1 0 2 2 2 1 Ezrin/radixin/moesin family DUF4677 PF15726.5 EWM22668.1 - 0.064 13.4 0.7 0.43 10.7 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4677) SMN PF06003.12 EWM22668.1 - 0.49 9.6 3.0 1.5 8.0 3.0 1.8 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Exonuc_VII_L PF02601.15 EWM22668.1 - 1.9 7.9 23.4 0.91 9.0 8.0 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit DEAD PF00270.29 EWM22669.1 - 3.6e-17 62.7 0.0 7.3e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EWM22669.1 - 1.9e-09 37.8 0.0 1.2e-08 35.2 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EWM22669.1 - 1.3e-05 25.3 0.0 2.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RET_CLD4 PF17813.1 EWM22670.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 RET Cadherin like domain 4 DOT1 PF08123.13 EWM22671.1 - 1.9e-08 34.1 0.0 9.4e-08 31.8 0.0 1.9 2 0 0 2 2 2 1 Histone methylation protein DOT1 GHMP_kinases_C PF08544.13 EWM22671.1 - 0.12 12.8 0.1 0.82 10.1 0.0 2.2 2 0 0 2 2 2 0 GHMP kinases C terminal DOT1 PF08123.13 EWM22672.1 - 2e-08 34.0 0.0 9.4e-08 31.8 0.0 1.9 2 0 0 2 2 2 1 Histone methylation protein DOT1 GHMP_kinases_C PF08544.13 EWM22672.1 - 0.12 12.8 0.1 0.82 10.1 0.0 2.2 2 0 0 2 2 2 0 GHMP kinases C terminal DOT1 PF08123.13 EWM22673.1 - 1.5e-08 34.4 0.0 8e-08 32.1 0.0 1.9 2 0 0 2 2 2 1 Histone methylation protein DOT1 GHMP_kinases_C PF08544.13 EWM22673.1 - 0.092 13.1 0.1 0.71 10.3 0.0 2.2 2 0 0 2 2 2 0 GHMP kinases C terminal Arf PF00025.21 EWM22674.1 - 5.2e-48 162.8 0.0 6.6e-48 162.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EWM22674.1 - 1e-11 44.7 0.0 1.3e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EWM22674.1 - 9.4e-10 38.8 0.0 1.7e-09 38.0 0.0 1.4 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EWM22674.1 - 1e-09 38.0 0.1 2.8e-05 23.5 0.0 2.5 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EWM22674.1 - 4.1e-06 26.3 0.0 5.5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EWM22674.1 - 9.9e-05 21.8 0.0 0.00011 21.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EWM22674.1 - 0.00091 19.3 0.0 0.0022 18.0 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EWM22674.1 - 0.013 15.1 0.0 0.8 9.2 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EWM22674.1 - 0.066 13.6 0.6 5.9 7.2 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain Cpn60_TCP1 PF00118.24 EWM22676.1 - 1.4e-146 489.0 7.1 1.6e-146 488.8 7.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nitro_FeMo-Co PF02579.17 EWM22676.1 - 0.023 15.0 0.5 8.7 6.7 0.0 3.4 3 0 0 3 3 3 0 Dinitrogenase iron-molybdenum cofactor SNAP PF14938.6 EWM22676.1 - 0.18 11.2 0.5 1 8.7 0.0 2.0 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP G-patch PF01585.23 EWM22678.1 - 4.3e-08 32.9 2.2 1e-07 31.7 2.2 1.6 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 EWM22678.1 - 1.1e-05 25.1 0.1 1.9e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_3 PF01494.19 EWM22679.1 - 1.3e-72 245.0 0.0 2e-72 244.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EWM22679.1 - 0.0061 16.8 0.0 0.017 15.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EWM22679.1 - 0.13 11.5 0.0 0.73 9.0 0.0 2.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase CooC_C PF15976.5 EWM22679.1 - 0.13 12.3 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 CS1-pili formation C-terminal Thi4 PF01946.17 EWM22679.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 EWM22679.1 - 0.16 11.2 0.0 0.32 10.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_C97 PF05903.14 EWM22680.1 - 1.8e-34 118.7 0.0 2.5e-34 118.3 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain HEAT PF02985.22 EWM22680.1 - 0.085 13.2 0.1 0.26 11.7 0.1 1.8 1 0 0 1 1 1 0 HEAT repeat CoA_binding_2 PF13380.6 EWM22681.1 - 3.7e-29 101.6 0.0 4.1e-29 101.4 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 EWM22681.1 - 0.0013 19.4 0.0 0.0018 18.9 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain PPR PF01535.20 EWM22683.1 - 5.7e-27 92.0 10.9 0.00033 20.7 0.0 9.1 10 0 0 10 10 10 6 PPR repeat PPR_2 PF13041.6 EWM22683.1 - 6.2e-26 90.4 0.0 4.6e-08 33.1 0.0 7.2 3 2 4 7 7 7 6 PPR repeat family PPR_1 PF12854.7 EWM22683.1 - 4.8e-21 74.2 0.0 0.002 17.8 0.0 6.0 6 0 0 6 6 6 5 PPR repeat PPR_3 PF13812.6 EWM22683.1 - 1.6e-15 56.9 0.0 0.00014 21.8 0.0 5.2 4 1 2 6 6 6 4 Pentatricopeptide repeat domain PPR_long PF17177.4 EWM22683.1 - 1.2e-08 34.6 5.3 0.0023 17.3 0.5 4.4 2 1 2 4 4 4 3 Pentacotripeptide-repeat region of PRORP Leptin PF02024.15 EWM22684.1 - 0.15 11.8 1.7 0.48 10.2 0.1 2.2 2 1 0 2 2 2 0 Leptin RRM_1 PF00076.22 EWM22685.1 - 3e-15 55.8 0.0 1.7e-14 53.4 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ThiF PF00899.21 EWM22686.1 - 4.6e-90 301.2 0.0 6.2e-64 215.7 0.0 2.6 1 1 1 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EWM22686.1 - 1.8e-67 228.0 0.0 2.9e-67 227.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_4HB PF16191.5 EWM22686.1 - 3.1e-15 56.1 0.0 8.4e-15 54.7 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_FCCH PF16190.5 EWM22686.1 - 2.2e-05 24.5 0.3 0.00037 20.6 0.3 2.5 1 1 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 EWM22686.1 - 0.0002 22.0 0.0 0.0011 19.6 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin fold domain PAP_fibrillin PF04755.12 EWM22687.1 - 1.8e-27 96.6 0.0 3.2e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 PAP_fibrillin adh_short PF00106.25 EWM22688.1 - 1.3e-42 145.5 0.0 1.6e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EWM22688.1 - 2.4e-26 92.7 0.0 3.1e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM22688.1 - 8.8e-09 35.5 0.1 1.3e-08 35.0 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EWM22688.1 - 4.9e-07 29.8 0.1 7.9e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EWM22688.1 - 0.00051 19.6 0.0 0.0022 17.5 0.0 1.9 2 1 0 3 3 3 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EWM22688.1 - 0.0024 17.3 0.0 0.034 13.5 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Lum_binding PF00677.17 EWM22689.1 - 3.7e-45 151.8 0.3 6.1e-22 77.4 0.0 2.2 2 0 0 2 2 2 2 Lumazine binding domain Imm65 PF15582.6 EWM22689.1 - 0.034 13.0 0.0 0.056 12.3 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 65 DUF4314 PF14192.6 EWM22689.1 - 0.15 12.0 0.3 0.46 10.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4314) Ins_P5_2-kin PF06090.12 EWM22690.1 - 2.4e-53 181.7 0.0 2.8e-53 181.5 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Ribosomal_L7Ae PF01248.26 EWM22691.1 - 2.3e-12 46.5 0.1 5.6e-12 45.2 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 EWM22691.1 - 0.00016 21.8 0.0 0.00034 20.7 0.0 1.5 2 0 0 2 2 2 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 EWM22691.1 - 0.15 11.9 0.1 0.31 10.9 0.1 1.4 1 0 0 1 1 1 0 PELOTA RNA binding domain RsgA_GTPase PF03193.16 EWM22693.1 - 1.1e-05 25.4 0.0 0.015 15.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EWM22693.1 - 0.00017 22.0 0.2 0.00053 20.4 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 EWM22693.1 - 0.00048 20.7 0.0 0.0018 18.8 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 EWM22693.1 - 0.00054 20.2 0.1 0.0019 18.5 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 EWM22693.1 - 0.0025 17.5 0.1 0.0055 16.4 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EWM22693.1 - 0.0035 17.1 0.0 0.0071 16.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.6 EWM22693.1 - 0.013 15.8 0.0 0.023 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EWM22693.1 - 0.013 15.4 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 EWM22693.1 - 0.014 15.5 0.0 0.027 14.5 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.19 EWM22693.1 - 0.016 14.8 0.1 0.028 14.0 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 EWM22693.1 - 0.017 15.3 0.0 0.032 14.4 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 EWM22693.1 - 0.029 14.5 0.2 0.2 11.8 0.2 2.3 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 EWM22693.1 - 0.031 13.3 0.0 0.19 10.8 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein NTPase_1 PF03266.15 EWM22693.1 - 0.039 13.9 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 NTPase Mg_chelatase PF01078.21 EWM22693.1 - 0.04 13.3 0.0 0.075 12.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EWM22693.1 - 0.065 13.2 0.5 0.22 11.5 0.1 2.2 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 EWM22693.1 - 0.23 11.2 0.0 0.41 10.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 EWM22693.1 - 0.24 10.9 0.0 1.3 8.6 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Guanylate_kin PF00625.21 EWM22693.1 - 0.25 11.0 0.0 0.42 10.3 0.0 1.3 1 0 0 1 1 1 0 Guanylate kinase DnaJ_C PF01556.18 EWM22695.1 - 1.4e-22 80.4 0.0 2e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EWM22695.1 - 2e-20 72.7 0.0 2.9e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Tex_N PF09371.10 EWM22699.1 - 0.00017 21.3 0.1 0.00042 20.0 0.1 1.6 1 1 1 2 2 2 1 Tex-like protein N-terminal domain Complex1_LYR_1 PF13232.6 EWM22699.1 - 0.016 15.8 0.7 0.041 14.5 0.4 1.8 1 1 1 2 2 2 0 Complex1_LYR-like Complex1_LYR PF05347.15 EWM22699.1 - 0.13 12.3 0.5 0.13 12.3 0.5 1.7 2 0 0 2 2 2 0 Complex 1 protein (LYR family) SMC_N PF02463.19 EWM22700.1 - 0.0039 16.7 0.0 0.0046 16.4 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain Guanylate_kin PF00625.21 EWM22701.1 - 5.4e-05 22.9 0.0 8.4e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Guanylate kinase Guanylate_kin PF00625.21 EWM22702.1 - 5.4e-05 23.0 0.0 8.4e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Guanylate kinase ABC_membrane PF00664.23 EWM22704.1 - 7.2e-34 117.7 6.4 9.9e-34 117.2 6.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EWM22704.1 - 1.5e-08 35.2 0.1 2.8e-08 34.4 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_28 PF13521.6 EWM22704.1 - 0.0054 17.0 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EWM22704.1 - 0.012 16.0 0.5 0.056 13.8 0.2 2.2 2 0 0 2 2 2 0 AAA ATPase domain ATP-synt_ab PF00006.25 EWM22704.1 - 0.03 14.0 0.0 0.37 10.4 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain RsgA_GTPase PF03193.16 EWM22704.1 - 0.039 13.9 0.1 0.075 12.9 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 EWM22704.1 - 0.07 13.4 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EWM22704.1 - 0.13 12.8 0.1 0.23 12.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain ABC_membrane_3 PF13748.6 EWM22704.1 - 0.14 11.4 1.0 0.29 10.3 1.0 1.6 1 1 0 1 1 1 0 ABC transporter transmembrane region Phage_holin_7_1 PF16081.5 EWM22704.1 - 0.14 12.4 0.2 0.8 9.9 0.0 2.3 3 0 0 3 3 3 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family MMR_HSR1 PF01926.23 EWM22704.1 - 0.14 12.2 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF87 PF01935.17 EWM22704.1 - 0.15 12.2 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 EWM22704.1 - 0.15 11.8 0.1 0.4 10.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 EWM22704.1 - 0.17 11.7 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Semialdhyde_dh PF01118.24 EWM22704.1 - 0.17 12.3 0.3 0.43 11.0 0.3 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Creatinase_N PF01321.18 EWM22705.1 - 1.3e-16 61.4 0.0 1.6e-16 61.2 0.0 1.0 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain ABC_membrane_2 PF06472.15 EWM22706.1 - 3.7e-05 23.3 0.1 0.00095 18.6 0.0 2.0 2 0 0 2 2 2 2 ABC transporter transmembrane region 2 Ank_5 PF13857.6 EWM22708.1 - 0.0093 16.3 0.1 0.04 14.2 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EWM22708.1 - 0.029 15.0 0.0 0.12 13.0 0.0 1.8 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EWM22708.1 - 0.053 14.1 0.1 0.13 12.8 0.1 1.7 1 1 0 1 1 1 0 Ankyrin repeats (many copies) NAD_binding_8 PF13450.6 EWM22709.1 - 5e-10 39.5 0.1 1e-09 38.5 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EWM22709.1 - 2.7e-05 24.0 0.0 4.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EWM22709.1 - 3.4e-05 22.7 0.0 4.4e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 EWM22709.1 - 9.3e-05 21.8 0.0 0.00013 21.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EWM22709.1 - 0.0002 20.7 0.0 0.00034 19.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 EWM22709.1 - 0.0007 19.6 0.0 0.0022 18.0 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 EWM22709.1 - 0.0098 15.2 0.2 1.7 7.8 0.0 2.1 1 1 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 EWM22709.1 - 0.04 13.0 0.2 0.058 12.5 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 EWM22709.1 - 0.044 13.1 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 EWM22709.1 - 0.055 12.5 0.1 0.098 11.7 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Semialdhyde_dh PF01118.24 EWM22709.1 - 0.086 13.3 0.0 1.1 9.7 0.0 2.2 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain MFS_1 PF07690.16 EWM22710.1 - 1.3e-24 86.8 17.3 1.3e-24 86.8 17.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EWM22710.1 - 8.7e-09 34.7 1.0 8.7e-09 34.7 1.0 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 EWM22710.1 - 1.7e-07 30.0 2.7 1.7e-06 26.6 2.7 2.3 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family SK_channel PF03530.14 EWM22710.1 - 0.0082 16.1 2.6 0.44 10.5 1.1 2.8 2 0 0 2 2 2 1 Calcium-activated SK potassium channel Tudor-knot PF11717.8 EWM22711.1 - 0.00051 19.9 0.2 0.00081 19.2 0.2 1.3 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Tudor_4 PF18358.1 EWM22711.1 - 0.0051 16.4 0.7 0.009 15.6 0.7 1.4 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain MBT PF02820.18 EWM22711.1 - 0.16 12.3 0.1 0.25 11.7 0.1 1.2 1 0 0 1 1 1 0 mbt repeat MIT PF04212.18 EWM22712.1 - 5.7e-15 55.1 0.8 8.9e-15 54.5 0.8 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Cyclase_polyket PF04673.12 EWM22712.1 - 0.084 13.1 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Polyketide synthesis cyclase UCH PF00443.29 EWM22713.1 - 7.4e-24 84.6 0.0 3.5e-16 59.5 0.0 2.1 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EWM22713.1 - 5.3e-08 32.8 0.0 0.00032 20.4 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase adh_short PF00106.25 EWM22715.1 - 4.9e-24 84.9 0.0 5e-20 71.8 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EWM22715.1 - 2.4e-15 56.8 0.0 3.6e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM22715.1 - 0.0017 18.3 0.0 0.0041 17.0 0.0 1.6 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 EWM22715.1 - 0.067 13.0 0.2 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Chloroa_b-bind PF00504.21 EWM22717.1 - 1e-40 139.9 0.1 1.4e-40 139.4 0.1 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DRMBL PF07522.14 EWM22722.1 - 2.5e-18 66.3 0.0 4.1e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase RMMBL PF07521.12 EWM22722.1 - 0.03 14.3 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain Sod_Cu PF00080.20 EWM22723.1 - 4.3e-26 91.8 0.3 5.3e-26 91.5 0.3 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Syntaxin-6_N PF09177.11 EWM22724.1 - 1.3e-05 25.7 0.2 4.5e-05 23.9 0.0 2.0 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 EWM22724.1 - 0.00087 19.2 1.9 0.00087 19.2 1.9 2.1 3 0 0 3 3 3 1 SNARE domain Prominin PF05478.11 EWM22724.1 - 0.036 12.0 0.1 0.11 10.4 0.0 1.7 2 0 0 2 2 2 0 Prominin KELK PF15796.5 EWM22724.1 - 0.048 14.1 0.8 0.12 12.9 0.6 1.8 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T2SSF PF00482.23 EWM22724.1 - 0.08 12.9 1.1 0.83 9.6 0.2 2.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Ibs_toxin PF13956.6 EWM22724.1 - 0.77 9.8 6.7 1.6 8.9 6.7 1.5 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system Carboxyl_trans PF01039.22 EWM22725.1 - 4.1e-34 118.1 0.3 6.3e-34 117.5 0.1 1.4 2 0 0 2 2 2 1 Carboxyl transferase domain N_BRCA1_IG PF16158.5 EWM22726.1 - 2.3e-16 60.4 0.0 3.8e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene N_BRCA1_IG PF16158.5 EWM22727.1 - 1.8e-13 51.1 0.0 3.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene PB1 PF00564.24 EWM22728.1 - 0.00056 19.8 0.0 0.00088 19.2 0.0 1.3 1 0 0 1 1 1 1 PB1 domain Methyltransf_25 PF13649.6 EWM22731.1 - 5.7e-05 23.7 0.1 0.00019 22.1 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM22731.1 - 8.8e-05 22.3 0.2 0.00017 21.4 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM22731.1 - 0.0039 17.8 0.0 0.0098 16.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EWM22731.1 - 0.017 14.7 0.1 0.031 13.9 0.1 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DOT1 PF08123.13 EWM22731.1 - 0.019 14.5 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_32 PF13679.6 EWM22731.1 - 0.022 14.7 0.1 0.042 13.8 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EWM22731.1 - 0.083 13.6 0.2 0.22 12.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain CMAS PF02353.20 EWM22731.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 EWM22731.1 - 0.18 11.3 1.8 0.24 10.9 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase DUF4281 PF14108.6 EWM22731.1 - 0.21 12.0 0.0 0.34 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4281) Methyltransf_25 PF13649.6 EWM22732.1 - 5.7e-05 23.8 0.1 0.00018 22.1 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM22732.1 - 8.8e-05 22.3 0.2 0.00017 21.4 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM22732.1 - 0.0039 17.8 0.0 0.0098 16.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EWM22732.1 - 0.017 14.7 0.1 0.031 13.9 0.1 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DOT1 PF08123.13 EWM22732.1 - 0.019 14.5 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_32 PF13679.6 EWM22732.1 - 0.022 14.7 0.1 0.042 13.9 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EWM22732.1 - 0.083 13.6 0.2 0.21 12.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain CMAS PF02353.20 EWM22732.1 - 0.14 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 EWM22732.1 - 0.18 11.3 1.8 0.24 10.9 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase DUF4281 PF14108.6 EWM22732.1 - 0.21 12.0 0.0 0.34 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4281) Tetraspanin PF00335.20 EWM22734.1 - 0.6 9.8 23.4 22 4.7 7.5 3.1 1 1 1 2 2 2 0 Tetraspanin family AA_permease_2 PF13520.6 EWM22735.1 - 5.4e-11 42.0 11.1 6.6e-11 41.7 11.1 1.1 1 0 0 1 1 1 1 Amino acid permease Methyltransf_21 PF05050.12 EWM22736.1 - 3.9e-09 36.8 0.0 5e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain NUC153 PF08159.12 EWM22736.1 - 0.11 12.3 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 NUC153 domain TRAM_LAG1_CLN8 PF03798.16 EWM22737.1 - 6.5e-13 48.9 2.8 2.2e-12 47.1 2.8 1.8 1 1 0 1 1 1 1 TLC domain Glutaredoxin PF00462.24 EWM22738.1 - 9.5e-19 67.4 0.0 1.5e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 EWM22738.1 - 0.00018 21.8 0.0 0.00031 21.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain SH3BGR PF04908.15 EWM22738.1 - 0.069 13.3 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein MAPKK1_Int PF08923.10 EWM22740.1 - 1.5e-14 53.8 0.0 3.5e-13 49.4 0.0 2.4 2 1 0 2 2 2 1 Mitogen-activated protein kinase kinase 1 interacting Robl_LC7 PF03259.17 EWM22740.1 - 0.046 13.5 0.0 0.1 12.4 0.0 1.7 1 1 0 1 1 1 0 Roadblock/LC7 domain TPR_10 PF13374.6 EWM22740.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4107 PF13389.6 EWM22741.1 - 0.33 11.1 0.8 0.69 10.1 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4107) GAPT PF11770.8 EWM22743.1 - 1.1 9.1 4.6 0.45 10.4 0.7 2.0 1 1 1 2 2 2 0 GRB2-binding adapter (GAPT) Chromate_transp PF02417.15 EWM22744.1 - 7.6e-61 204.8 40.2 5.3e-33 114.4 21.0 2.5 3 0 0 3 3 3 2 Chromate transporter DUF455 PF04305.14 EWM22745.1 - 4.5e-63 213.1 0.0 5.1e-63 212.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF455) zf-Tim10_DDP PF02953.15 EWM22746.1 - 1.1e-21 76.2 6.5 1.4e-21 75.9 6.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Herpes_BLRF2 PF05812.12 EWM22746.1 - 0.019 15.1 0.1 0.022 14.9 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein DUF842 PF05811.13 EWM22746.1 - 0.033 13.9 6.2 0.081 12.6 6.2 1.6 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DUF3500 PF12006.8 EWM22746.1 - 0.059 12.8 0.2 0.066 12.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3500) zf-Tim10_DDP PF02953.15 EWM22747.1 - 3.7e-21 74.6 6.5 3.7e-21 74.6 6.5 1.5 2 0 0 2 2 2 1 Tim10/DDP family zinc finger Herpes_BLRF2 PF05812.12 EWM22747.1 - 0.0084 16.2 0.2 0.012 15.7 0.2 1.2 1 0 0 1 1 1 1 Herpesvirus BLRF2 protein DUF3500 PF12006.8 EWM22747.1 - 0.011 15.3 0.1 0.012 15.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3500) SF1-HH PF16275.5 EWM22747.1 - 0.1 12.9 0.2 0.16 12.3 0.2 1.4 1 1 0 1 1 1 0 Splicing factor 1 helix-hairpin domain DUF4140 PF13600.6 EWM22748.1 - 1.2 9.6 10.1 14 6.2 0.4 3.9 4 0 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) Med9 PF07544.13 EWM22748.1 - 6.7 6.9 6.1 13 5.9 0.1 3.0 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 VATC PF18716.1 EWM22749.1 - 6.9e-10 38.6 1.5 6.9e-10 38.6 1.5 1.7 2 0 0 2 2 2 1 Vms1-associating treble clef domain Ank_5 PF13857.6 EWM22749.1 - 1.7e-05 25.0 0.0 4.3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EWM22749.1 - 0.00018 21.8 0.0 0.00033 21.0 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 EWM22749.1 - 0.0017 18.7 0.0 0.0037 17.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 EWM22749.1 - 0.0067 17.0 0.0 0.012 16.2 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EWM22749.1 - 0.0067 17.0 0.0 0.31 11.7 0.0 1.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Pkinase_fungal PF17667.1 EWM22749.1 - 0.0077 15.1 0.1 0.0088 14.9 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase CMS1 PF14617.6 EWM22749.1 - 0.019 14.3 3.0 0.026 13.9 3.0 1.1 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Ima1_N PF09779.9 EWM22749.1 - 0.056 14.3 0.5 0.086 13.7 0.5 1.3 1 0 0 1 1 1 0 Ima1 N-terminal domain Eapp_C PF10238.9 EWM22749.1 - 0.11 12.6 4.2 0.17 11.9 4.2 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein RR_TM4-6 PF06459.12 EWM22749.1 - 0.31 10.8 4.7 0.4 10.5 4.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 C1_2 PF03107.16 EWM22749.1 - 0.35 11.2 2.9 0.3 11.5 1.1 1.8 2 0 0 2 2 2 0 C1 domain DUF4746 PF15928.5 EWM22749.1 - 7.9 5.8 7.0 12 5.2 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) ABC_membrane PF00664.23 EWM22750.1 - 2.8e-56 191.2 0.5 4.7e-56 190.5 0.5 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EWM22750.1 - 2.2e-27 96.2 0.0 4.1e-27 95.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EWM22750.1 - 5e-07 29.4 0.0 0.00044 19.8 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EWM22750.1 - 0.0016 18.8 0.5 0.1 13.0 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EWM22750.1 - 0.0018 18.3 0.1 0.58 10.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 EWM22750.1 - 0.0053 16.5 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 EWM22750.1 - 0.038 14.4 0.2 6.9 7.1 0.0 2.7 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EWM22750.1 - 0.09 13.1 0.1 1.5 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EWM22750.1 - 0.11 12.2 0.0 0.91 9.2 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 EWM22750.1 - 0.11 12.4 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_21 PF13304.6 EWM22750.1 - 0.16 11.7 1.4 6.5 6.5 0.2 2.3 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF2680 PF10925.8 EWM22750.1 - 0.21 11.6 0.1 0.57 10.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) PLAC8 PF04749.17 EWM22752.1 - 2.1e-16 60.7 2.6 2.4e-16 60.5 0.8 2.1 2 0 0 2 2 2 1 PLAC8 family PrsW-protease PF13367.6 EWM22752.1 - 3.5e-11 42.9 6.7 3.5e-11 42.9 6.7 2.8 3 0 0 3 3 3 1 PrsW family intramembrane metalloprotease YjcB PF15940.5 EWM22753.1 - 0.024 14.8 0.1 0.039 14.1 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function DUF1769 PF08588.10 EWM22754.1 - 1.4e-05 25.2 0.0 3.1e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) KH_1 PF00013.29 EWM22755.1 - 1.2e-22 79.5 0.2 5.7e-10 38.9 0.1 2.3 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 EWM22755.1 - 6.1e-07 29.2 1.2 0.022 14.6 0.1 2.3 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 EWM22755.1 - 0.3 11.2 0.9 21 5.3 0.1 2.4 2 0 0 2 2 2 0 NusA-like KH domain Clat_adaptor_s PF01217.20 EWM22756.1 - 1.5e-23 83.3 0.1 1.9e-23 83.0 0.1 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Peptidase_C39 PF03412.15 EWM22756.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase C39 family Transp_cyt_pur PF02133.15 EWM22759.1 - 1.4e-17 63.6 18.0 1.8e-17 63.3 18.0 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Methyltrans_RNA PF04452.14 EWM22762.1 - 4.7e-26 91.5 0.0 4.1e-25 88.5 0.0 1.9 1 1 0 1 1 1 1 RNA methyltransferase ABC2_membrane_2 PF12679.7 EWM22763.1 - 0.22 10.7 2.8 0.34 10.2 2.8 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Bax1-I PF01027.20 EWM22763.1 - 0.39 10.5 8.4 3.6 7.4 1.1 2.1 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 KTI12 PF08433.10 EWM22764.1 - 2.2e-23 83.1 0.0 2.5e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Mito_carr PF00153.27 EWM22765.1 - 5.4e-53 176.9 1.7 2.5e-17 62.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Cbl_N3 PF02762.14 EWM22765.1 - 0.064 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain DUF1350 PF07082.11 EWM22766.1 - 7.1e-31 107.4 0.0 3.5e-23 82.2 0.0 2.8 2 2 0 2 2 2 2 Protein of unknown function (DUF1350) CARMIL_C PF16000.5 EWM22766.1 - 0.033 13.8 0.7 0.18 11.4 0.0 2.1 2 0 0 2 2 2 0 CARMIL C-terminus Rad10 PF03834.14 EWM22768.1 - 4.6e-06 26.6 0.0 6.3e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Rad10 PF03834.14 EWM22769.1 - 4.6e-19 68.5 0.0 5.7e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Got1 PF04178.12 EWM22772.1 - 2.1e-26 92.6 11.7 3e-26 92.1 11.7 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Deltameth_res PF16020.5 EWM22772.1 - 0.96 9.4 4.0 4.9 7.1 0.4 2.7 2 0 0 2 2 2 0 Deltamethrin resistance PI3_PI4_kinase PF00454.27 EWM22773.1 - 5.3e-44 150.9 0.0 1.6e-43 149.3 0.0 1.9 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EWM22773.1 - 1.5e-05 24.7 0.0 3.5e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 FATC domain TPR_7 PF13176.6 EWM22773.1 - 0.018 15.0 2.0 0.06 13.4 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EWM22773.1 - 0.085 13.0 0.0 0.085 13.0 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EWM22773.1 - 1.8 8.9 6.0 4.1 7.8 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Cation_ATPase_C PF00689.21 EWM22774.1 - 2.7e-41 141.3 3.1 4.5e-41 140.5 3.1 1.4 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EWM22774.1 - 3.8e-18 65.3 0.0 6.8e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EWM22774.1 - 6e-14 52.8 2.7 9.3e-09 35.9 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EWM22774.1 - 0.0012 18.7 1.1 0.093 12.5 0.7 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EWM22774.1 - 0.19 12.1 0.0 1.5 9.2 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase NUC194 PF08163.12 EWM22775.1 - 3.1e-09 36.3 0.0 0.009 15.0 0.2 3.1 2 1 0 2 2 2 2 NUC194 domain RNase_Zc3h12a PF11977.8 EWM22776.1 - 5e-12 45.9 0.0 1.6e-11 44.2 0.0 1.7 1 1 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain PRORP PF16953.5 EWM22776.1 - 0.059 12.9 0.0 0.076 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein-only RNase P NMT1 PF09084.11 EWM22780.1 - 3.9e-10 40.0 0.0 4.9e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like THF_DHG_CYH PF00763.23 EWM22781.1 - 5.6e-06 26.6 0.0 7.9e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain DUF2798 PF11391.8 EWM22784.1 - 0.0083 16.1 0.1 0.015 15.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2798) Mitofilin PF09731.9 EWM22784.1 - 1.7 7.4 30.0 2.5 6.8 30.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Di19_C PF14571.6 EWM22784.1 - 8.1 7.0 7.9 3 8.4 0.6 2.7 3 0 0 3 3 3 0 Stress-induced protein Di19, C-terminal Pkinase PF00069.25 EWM22786.1 - 2.1e-63 214.2 0.0 2.9e-63 213.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM22786.1 - 4e-28 98.4 0.0 5.7e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EWM22786.1 - 3.1e-05 23.4 0.1 0.00025 20.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EWM22786.1 - 0.078 11.7 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Nkap_C PF06047.11 EWM22787.1 - 2.6e-32 111.0 1.9 3.6e-32 110.5 1.9 1.2 1 0 0 1 1 1 1 NF-kappa-B-activating protein C-terminal domain DTW PF03942.15 EWM22787.1 - 0.12 12.1 0.3 0.13 11.9 0.3 1.0 1 0 0 1 1 1 0 DTW domain RNase_PH PF01138.21 EWM22788.1 - 1.1e-26 93.9 0.0 3.5e-26 92.3 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Lactate_perm PF02652.14 EWM22788.1 - 0.37 9.5 1.0 0.5 9.1 1.0 1.1 1 0 0 1 1 1 0 L-lactate permease RNase_PH PF01138.21 EWM22789.1 - 8.6e-30 103.9 0.0 2.7e-29 102.3 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Lactate_perm PF02652.14 EWM22789.1 - 0.37 9.5 1.0 0.5 9.0 1.0 1.1 1 0 0 1 1 1 0 L-lactate permease ThiF PF00899.21 EWM22791.1 - 0.096 12.0 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 ThiF family DUF4551 PF15087.6 EWM22791.1 - 0.19 10.5 1.7 0.22 10.3 1.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Rhodanese PF00581.20 EWM22794.1 - 2.3e-12 47.4 0.0 3.5e-12 46.8 0.0 1.3 1 1 0 1 1 1 1 Rhodanese-like domain Septin PF00735.18 EWM22796.1 - 1.4e-13 50.8 0.0 1.8e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Septin Septin PF00735.18 EWM22797.1 - 0.00067 19.0 0.0 0.00076 18.8 0.0 1.0 1 0 0 1 1 1 1 Septin Methyltransf_21 PF05050.12 EWM22800.1 - 0.00017 21.7 0.0 0.00022 21.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain TylF PF05711.11 EWM22801.1 - 1.2e-69 234.4 0.0 1.5e-69 234.1 0.0 1.1 1 0 0 1 1 1 1 Macrocin-O-methyltransferase (TylF) Methyltransf_24 PF13578.6 EWM22801.1 - 2.7e-06 28.3 0.0 5e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.12 EWM22801.1 - 0.062 13.0 0.0 0.48 10.1 0.0 2.0 2 0 0 2 2 2 0 Cephalosporin hydroxylase DUF3420 PF11900.8 EWM22803.1 - 0.1 12.8 1.0 1.1 9.5 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3420) MID_MedPIWI PF18296.1 EWM22803.1 - 0.36 10.6 4.4 0.14 11.9 1.2 2.1 2 0 0 2 2 2 0 MID domain of medPIWI DUF2052 PF09747.9 EWM22803.1 - 0.37 10.9 4.9 0.89 9.7 4.9 1.6 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) CCDC24 PF15669.5 EWM22803.1 - 3.2 7.6 8.5 1.4 8.7 4.6 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family DUF3420 PF11900.8 EWM22804.1 - 0.095 12.9 1.0 1 9.5 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3420) MID_MedPIWI PF18296.1 EWM22804.1 - 0.26 11.0 4.0 0.13 12.0 1.2 2.1 2 0 0 2 2 2 0 MID domain of medPIWI DUF2052 PF09747.9 EWM22804.1 - 0.35 11.0 5.0 0.84 9.7 5.0 1.7 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) CCDC24 PF15669.5 EWM22804.1 - 3.8 7.3 8.6 1.3 8.8 4.6 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family TrfA PF07042.11 EWM22808.1 - 0.034 13.2 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 TrfA protein Paf1 PF03985.13 EWM22809.1 - 0.023 13.7 0.9 0.041 12.9 0.9 1.3 1 0 0 1 1 1 0 Paf1 GTP_CH_N PF12471.8 EWM22810.1 - 2.3e-81 272.2 0.0 3.8e-81 271.5 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 EWM22810.1 - 1.1e-14 54.3 0.0 1.7e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II Pribosyltran_N PF13793.6 EWM22811.1 - 3.2e-41 139.9 0.0 8.5e-40 135.3 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EWM22811.1 - 9.2e-19 68.2 0.1 3e-18 66.5 0.0 1.8 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EWM22811.1 - 1.9e-10 40.5 0.9 4.9e-10 39.2 0.1 2.0 2 0 0 2 2 2 1 Phosphoribosyl transferase domain TBCC PF07986.12 EWM22811.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Tubulin binding cofactor C UPRTase PF14681.6 EWM22811.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 EWM22811.1 - 0.2 11.2 0.2 0.85 9.1 0.0 1.9 1 1 1 2 2 2 0 Phosphoribosyl transferase Ceramidase PF05875.12 EWM22813.1 - 2.2e-18 66.7 0.7 6.8e-18 65.0 0.7 1.7 1 1 0 1 1 1 1 Ceramidase CitMHS PF03600.16 EWM22813.1 - 5.8 6.0 8.5 1.3 8.1 5.1 1.6 2 0 0 2 2 2 0 Citrate transporter Ank_4 PF13637.6 EWM22814.1 - 2.6e-30 104.4 0.2 5.4e-14 52.4 0.1 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EWM22814.1 - 2.4e-27 95.4 0.0 1.8e-14 54.1 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EWM22814.1 - 4e-27 93.4 0.0 1.6e-07 31.5 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 EWM22814.1 - 1.4e-25 89.0 2.0 4.6e-11 42.7 0.2 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EWM22814.1 - 3.8e-21 72.9 0.0 1.9e-05 24.6 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat PPR PF01535.20 EWM22814.1 - 0.11 12.7 0.1 0.3 11.4 0.1 1.7 1 0 0 1 1 1 0 PPR repeat Calici_MSP PF05752.11 EWM22815.1 - 0.062 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Calicivirus minor structural protein SDA1 PF05285.12 EWM22817.1 - 1.4e-24 87.2 32.2 2.2e-24 86.6 32.2 1.2 1 0 0 1 1 1 1 SDA1 Polyketide_cyc PF03364.20 EWM22819.1 - 4.2e-08 33.5 0.1 8.1e-08 32.5 0.1 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 EWM22819.1 - 0.0056 17.0 0.1 1.1 9.6 0.0 2.3 2 0 0 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport FA_desaturase PF00487.24 EWM22821.1 - 2 8.2 10.9 3.4 7.4 10.9 1.4 1 0 0 1 1 1 0 Fatty acid desaturase Amino_oxidase PF01593.24 EWM22822.1 - 3.2e-41 142.1 4.7 2.2e-26 93.2 0.1 2.3 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EWM22822.1 - 9e-11 41.9 0.4 2e-10 40.8 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EWM22822.1 - 1.1e-05 24.7 0.3 1.6e-05 24.2 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EWM22822.1 - 2e-05 24.0 0.2 2.5e-05 23.7 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EWM22822.1 - 0.0001 22.0 2.0 0.00014 21.6 2.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EWM22822.1 - 0.0015 17.8 0.3 0.0031 16.8 0.3 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 EWM22822.1 - 0.0056 15.4 0.3 0.0082 14.9 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 EWM22822.1 - 0.012 15.0 0.8 0.019 14.3 0.8 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 EWM22822.1 - 0.015 14.6 0.3 0.022 14.0 0.3 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EWM22822.1 - 0.018 14.4 1.3 0.025 14.0 1.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EWM22822.1 - 0.054 12.5 0.1 0.081 12.0 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 EWM22822.1 - 0.073 12.1 0.7 0.11 11.5 0.7 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A TrkA_N PF02254.18 EWM22822.1 - 0.13 12.5 0.1 0.25 11.6 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain HAD_2 PF13419.6 EWM22825.1 - 2.1e-23 83.3 0.0 2.6e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EWM22825.1 - 7.1e-15 55.9 0.3 1.1e-13 52.0 0.3 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EWM22825.1 - 5.8e-07 29.5 0.1 1.5e-06 28.2 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 EWM22825.1 - 2.2e-05 24.9 0.1 5.9e-05 23.6 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EWM22825.1 - 0.047 13.8 0.0 6.8 6.9 0.0 2.5 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase FANCL_C PF11793.8 EWM22827.1 - 2.1e-19 69.5 1.8 4.2e-19 68.5 1.8 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain WD-3 PF09765.9 EWM22827.1 - 5.6e-14 52.1 0.0 6.9e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 WD-repeat region zf-RING_2 PF13639.6 EWM22827.1 - 0.0041 17.4 9.3 0.024 15.0 9.3 2.2 1 1 1 2 2 2 1 Ring finger domain zf-HC5HC2H PF13771.6 EWM22827.1 - 0.012 15.9 2.0 0.018 15.3 2.0 1.3 1 0 0 1 1 1 0 PHD-like zinc-binding domain Cys_rich_CPXG PF14255.6 EWM22827.1 - 0.023 14.6 5.0 0.14 12.1 0.1 2.3 2 0 0 2 2 2 0 Cysteine-rich CPXCG zf-HC5HC2H_2 PF13832.6 EWM22827.1 - 0.032 14.4 0.4 0.06 13.5 0.4 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-ANAPC11 PF12861.7 EWM22827.1 - 0.09 12.8 3.8 0.42 10.7 3.5 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EWM22827.1 - 0.49 10.7 6.5 1.4 9.2 6.5 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain SUIM_assoc PF16619.5 EWM22828.1 - 1.2e-06 28.5 4.4 0.0011 19.0 0.0 3.4 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 ArfGap PF01412.18 EWM22828.1 - 0.00019 21.5 0.1 0.00019 21.5 0.1 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PAT1 PF09770.9 EWM22828.1 - 1.4 7.1 23.5 1.8 6.8 23.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.16 EWM22828.1 - 2.5 8.1 4.9 3.2 7.7 4.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 EWM22828.1 - 3.3 6.4 6.2 3.9 6.1 6.2 1.1 1 0 0 1 1 1 0 Presenilin KH_1 PF00013.29 EWM22829.1 - 0.041 13.7 0.0 0.068 13.0 0.0 1.4 1 0 0 1 1 1 0 KH domain SAP PF02037.27 EWM22830.1 - 1e-08 34.7 0.1 2.6e-08 33.4 0.1 1.7 1 0 0 1 1 1 1 SAP domain RAP PF08373.10 EWM22830.1 - 1.3e-05 25.1 0.1 6e-05 23.1 0.1 2.0 1 1 0 1 1 1 1 RAP domain HTH_31 PF13560.6 EWM22830.1 - 0.0055 17.0 1.0 0.051 13.9 0.3 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HeH PF12949.7 EWM22830.1 - 0.083 12.6 0.2 0.24 11.1 0.1 1.9 1 1 0 1 1 1 0 HeH/LEM domain KH_1 PF00013.29 EWM22832.1 - 6e-33 112.5 0.1 2.3e-11 43.3 0.0 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EWM22832.1 - 1.4e-06 28.0 0.1 0.33 10.8 0.0 3.6 3 0 0 3 3 3 2 KH domain KH_4 PF13083.6 EWM22832.1 - 0.017 15.0 6.4 0.11 12.4 0.0 3.2 3 0 0 3 3 3 0 KH domain KH_5 PF13184.6 EWM22832.1 - 0.026 14.6 0.4 45 4.2 0.0 3.2 3 0 0 3 3 3 0 NusA-like KH domain CDC45 PF02724.14 EWM22832.1 - 0.11 10.7 11.8 0.14 10.4 11.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.22 EWM22832.1 - 0.19 10.9 0.4 0.17 11.1 0.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter PRP38_assoc PF12871.7 EWM22832.1 - 4.9 7.8 28.7 0.17 12.5 22.4 1.8 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Presenilin PF01080.17 EWM22832.1 - 5.2 5.7 8.8 6.5 5.4 8.8 1.1 1 0 0 1 1 1 0 Presenilin Merozoite_SPAM PF07133.11 EWM22832.1 - 6.9 6.6 22.3 12 5.9 22.3 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Apt1 PF10351.9 EWM22832.1 - 9.4 5.0 8.9 12 4.6 8.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DIOX_N PF14226.6 EWM22833.1 - 1.7e-13 51.4 0.1 9.5e-08 32.8 0.1 3.6 2 1 1 3 3 3 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EWM22833.1 - 3.6e-07 30.6 0.0 2.8e-06 27.7 0.0 2.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Zn_clus PF00172.18 EWM22836.1 - 8.1e-05 22.7 9.8 0.00014 21.9 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank PF00023.30 EWM22837.1 - 1.5e-19 69.5 2.8 1.8e-07 31.3 0.1 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 EWM22837.1 - 2.7e-18 66.3 0.0 1.6e-09 38.2 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EWM22837.1 - 1.5e-16 58.8 0.3 6.4e-06 26.1 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 EWM22837.1 - 1.6e-15 57.2 0.0 4e-05 24.1 0.0 4.1 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EWM22837.1 - 5.6e-15 55.2 1.0 3.5e-08 33.6 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Claudin_2 PF13903.6 EWM22840.1 - 0.053 13.3 1.9 0.091 12.5 1.9 1.4 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DuoxA PF10204.9 EWM22840.1 - 0.15 11.1 1.4 0.23 10.4 1.4 1.3 1 0 0 1 1 1 0 Dual oxidase maturation factor NUDIX PF00293.28 EWM22841.1 - 1.1e-16 61.1 0.0 1.8e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Imm74 PF15603.6 EWM22841.1 - 0.15 12.2 0.0 2.7 8.3 0.0 2.2 2 0 0 2 2 2 0 Immunity protein 74 TPR_19 PF14559.6 EWM22842.1 - 5.7e-05 23.6 7.4 0.00038 20.9 1.7 3.0 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EWM22842.1 - 0.00015 21.7 10.5 0.22 11.8 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EWM22842.1 - 0.00016 21.3 0.9 0.2 11.4 0.3 3.6 3 1 1 4 4 4 1 TPR repeat TPR_2 PF07719.17 EWM22842.1 - 0.00088 19.2 18.9 0.028 14.5 0.6 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EWM22842.1 - 0.0077 17.0 14.2 0.26 12.2 0.6 5.0 2 1 3 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 EWM22842.1 - 0.017 15.0 12.3 0.096 12.6 0.3 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat Macoilin PF09726.9 EWM22842.1 - 0.13 10.8 0.7 0.15 10.6 0.7 1.1 1 0 0 1 1 1 0 Macoilin family TPR_17 PF13431.6 EWM22842.1 - 0.21 12.0 1.5 39 4.9 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Exo70 PF03081.15 EWM22842.1 - 0.28 10.2 1.2 0.61 9.1 1.2 1.5 2 0 0 2 2 2 0 Exo70 exocyst complex subunit TPR_20 PF14561.6 EWM22842.1 - 0.31 11.4 2.2 3.7 7.9 1.3 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EWM22842.1 - 0.36 10.7 13.1 2.9 7.9 0.3 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 EWM22842.1 - 0.41 11.0 13.7 0.98 9.8 4.7 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 EWM22842.1 - 0.57 11.0 5.9 4 8.3 0.3 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 EWM22842.1 - 0.95 10.2 13.4 0.13 12.9 2.9 3.8 4 1 1 5 5 5 0 Tetratricopeptide repeat ATG16 PF08614.11 EWM22842.1 - 2.2 8.5 6.9 6.4 7.0 2.9 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF508 PF04370.12 EWM22842.1 - 2.6 7.8 13.7 5.5 6.7 13.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF508) IQCJ-SCHIP1 PF15157.6 EWM22842.1 - 8.3 6.2 6.4 16 5.3 6.4 1.4 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif CwfJ_C_2 PF04676.14 EWM22844.1 - 2e-06 28.6 0.0 2.9e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Hpt PF01627.23 EWM22846.1 - 0.064 13.5 0.0 0.16 12.3 0.0 1.6 2 0 0 2 2 2 0 Hpt domain RRM_1 PF00076.22 EWM22847.1 - 2.8e-27 94.3 0.0 1.4e-15 56.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EWM22847.1 - 0.00048 20.2 0.0 0.0009 19.3 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif RRM_3 PF08777.11 EWM22847.1 - 0.18 11.8 0.0 1.9 8.6 0.0 2.0 2 0 0 2 2 2 0 RNA binding motif RRM_1 PF00076.22 EWM22848.1 - 2.5e-09 36.8 0.0 3.7e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M17 PF00883.21 EWM22849.1 - 3.4e-58 197.4 0.0 3.8e-58 197.2 0.0 1.0 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain ANAPC3 PF12895.7 EWM22850.1 - 1.1e-14 54.4 0.5 1.8e-14 53.7 0.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 EWM22850.1 - 0.001 19.5 6.0 0.11 13.2 0.9 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EWM22850.1 - 0.018 15.6 2.2 0.039 14.4 1.3 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EWM22850.1 - 0.19 12.6 4.1 1.7 9.7 1.2 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EWM22850.1 - 0.48 11.1 4.0 0.96 10.2 1.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Vps53_N PF04100.12 EWM22853.1 - 5.1e-93 312.0 0.5 8.4e-82 275.1 0.6 2.2 2 0 0 2 2 2 2 Vps53-like, N-terminal Sec6 PF06046.13 EWM22853.1 - 7.7e-09 34.5 0.2 1.7e-06 26.7 0.0 2.7 3 0 0 3 3 3 2 Exocyst complex component Sec6 Vps54_N PF10475.9 EWM22853.1 - 1e-08 34.9 4.2 2.2e-08 33.7 4.2 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex COG7 PF10191.9 EWM22853.1 - 0.0062 14.8 2.8 0.071 11.3 0.0 2.9 3 0 0 3 3 3 1 Golgi complex component 7 (COG7) DUF2451 PF10474.9 EWM22853.1 - 0.011 15.5 0.7 0.2 11.4 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function C-terminus (DUF2451) RINT1_TIP1 PF04437.13 EWM22853.1 - 0.025 13.5 0.3 0.14 11.0 0.0 2.4 2 2 0 2 2 2 0 RINT-1 / TIP-1 family COG4 PF08318.12 EWM22853.1 - 0.035 13.2 0.0 0.064 12.3 0.0 1.4 1 0 0 1 1 1 0 COG4 transport protein DUF1202 PF06717.11 EWM22853.1 - 0.036 13.5 0.1 0.063 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) DUF3446 PF11928.8 EWM22853.1 - 0.048 14.0 7.9 0.1 12.9 1.2 3.2 2 0 0 2 2 2 0 Early growth response N-terminal domain zf-C4H2 PF10146.9 EWM22853.1 - 0.13 12.6 0.5 0.28 11.5 0.5 1.6 1 0 0 1 1 1 0 Zinc finger-containing protein COG5 PF10392.9 EWM22853.1 - 0.16 12.1 1.8 1.3 9.2 0.2 2.5 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Laminin_II PF06009.12 EWM22853.1 - 0.21 11.6 2.0 1.6 8.8 0.4 2.4 2 0 0 2 2 2 0 Laminin Domain II Alpha-2-MRAP_C PF06401.11 EWM22853.1 - 0.23 11.4 2.2 0.36 10.7 2.2 1.2 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain GAS PF13851.6 EWM22853.1 - 0.49 9.7 5.5 1.3 8.4 5.5 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 EWM22853.1 - 0.58 9.0 5.9 0.16 10.8 1.7 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein Phage_Mu_Gam PF07352.12 EWM22853.1 - 0.68 9.8 4.6 0.28 11.1 0.1 2.3 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein Baculo_PEP_C PF04513.12 EWM22853.1 - 0.93 9.5 6.4 2.7 8.0 1.5 2.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 EWM22853.1 - 1.1 9.3 5.1 9.1 6.4 1.2 2.5 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) COG2 PF06148.11 EWM22853.1 - 2.9 8.0 4.5 6 7.0 1.4 2.9 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DHR10 PF18595.1 EWM22853.1 - 3.9 7.6 8.5 0.87 9.7 3.2 2.5 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain Pkinase PF00069.25 EWM22854.1 - 1.8e-66 224.2 0.0 2.9e-66 223.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM22854.1 - 5.1e-29 101.3 0.0 1.9e-27 96.2 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 EWM22854.1 - 0.00027 21.4 0.1 0.00073 20.0 0.0 1.8 2 0 0 2 2 2 1 PH domain Kdo PF06293.14 EWM22854.1 - 0.016 14.6 0.0 0.036 13.4 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PH_3 PF14593.6 EWM22854.1 - 0.036 14.2 0.0 0.074 13.2 0.0 1.5 1 0 0 1 1 1 0 PH domain Haspin_kinase PF12330.8 EWM22854.1 - 0.075 12.0 0.0 0.075 12.0 0.0 2.3 2 1 1 3 3 3 0 Haspin like kinase domain TPR_1 PF00515.28 EWM22855.1 - 6.9e-37 123.8 7.6 3.1e-08 33.1 0.6 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 EWM22855.1 - 1.4e-35 118.5 10.5 6.4e-06 25.9 0.6 7.4 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 EWM22855.1 - 1e-27 96.5 8.6 3.1e-09 37.3 0.2 5.3 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 EWM22855.1 - 2.7e-25 87.7 0.3 2.1e-07 30.5 0.5 6.9 3 1 5 8 8 8 6 TPR repeat TPR_8 PF13181.6 EWM22855.1 - 7.7e-24 81.9 1.1 0.0021 18.2 0.0 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 EWM22855.1 - 8.4e-21 74.1 10.4 1.9e-06 28.0 0.2 6.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 EWM22855.1 - 4.7e-20 70.5 4.7 0.0032 17.7 0.1 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 EWM22855.1 - 1.4e-19 69.1 14.2 0.00017 22.1 0.4 7.9 1 1 7 8 8 8 6 Tetratricopeptide repeat TPR_19 PF14559.6 EWM22855.1 - 7e-19 68.1 10.2 1.9e-10 41.1 1.3 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EWM22855.1 - 1.9e-14 53.6 10.6 5.8e-06 26.4 0.1 4.2 2 1 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EWM22855.1 - 3.7e-13 48.5 6.0 0.01 15.8 0.0 6.7 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 EWM22855.1 - 2.5e-11 43.6 12.3 1.1e-06 28.7 1.7 4.7 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 EWM22855.1 - 6.8e-11 42.1 6.3 0.51 11.1 0.3 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat NARP1 PF12569.8 EWM22855.1 - 9.9e-07 28.0 0.2 0.021 13.8 0.1 2.6 2 1 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 EWM22855.1 - 1.9e-06 27.3 5.2 0.00018 20.8 0.6 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 EWM22855.1 - 3.7e-05 23.9 0.1 1 10.2 0.1 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 EWM22855.1 - 0.00018 21.8 2.4 0.011 16.0 0.9 3.3 2 2 3 5 5 5 1 Tetratricopeptide repeat ChAPs PF09295.10 EWM22855.1 - 0.0013 17.8 0.1 0.1 11.6 0.0 2.5 1 1 2 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) HrpB1_HrpK PF09613.10 EWM22855.1 - 0.0021 17.7 1.4 0.0046 16.6 0.1 2.1 2 1 0 2 2 2 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_MalT PF17874.1 EWM22855.1 - 0.0023 17.4 4.4 0.011 15.1 1.0 2.7 2 1 1 3 3 3 1 MalT-like TPR region TPR_21 PF09976.9 EWM22855.1 - 0.0032 17.2 4.4 0.035 13.8 0.5 3.4 2 1 2 4 4 4 1 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 EWM22855.1 - 0.006 16.4 12.4 7.5 6.6 0.5 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EWM22855.1 - 0.014 15.4 0.6 0.063 13.3 0.0 2.4 3 1 0 3 3 2 0 Putative TPR-like repeat FAT PF02259.23 EWM22855.1 - 0.02 14.1 1.7 0.4 9.8 0.2 2.6 2 1 1 3 3 3 0 FAT domain DUF410 PF04190.13 EWM22855.1 - 0.034 14.0 0.8 6.7 6.4 0.1 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF410) BTAD PF03704.17 EWM22855.1 - 0.2 12.1 7.7 0.053 14.0 1.3 2.5 3 0 0 3 3 3 0 Bacterial transcriptional activator domain CLN3 PF02487.17 EWM22856.1 - 1.5e-86 291.0 0.0 3.1e-86 289.9 0.0 1.4 1 1 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 EWM22856.1 - 0.00017 20.6 6.6 0.00017 20.6 6.6 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily CLN3 PF02487.17 EWM22857.1 - 1.6e-86 290.9 0.0 3.4e-86 289.8 0.0 1.4 1 1 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 EWM22857.1 - 9.4e-05 21.5 5.8 9.4e-05 21.5 5.8 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily CLN3 PF02487.17 EWM22858.1 - 4.3e-66 223.6 0.0 9.9e-66 222.4 0.0 1.5 1 1 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 EWM22858.1 - 3.6e-06 26.1 17.8 9.9e-05 21.4 6.1 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily RRM_1 PF00076.22 EWM22861.1 - 7e-32 109.1 0.0 1e-15 57.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EWM22861.1 - 4.7e-09 36.2 0.1 0.00011 22.3 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EWM22861.1 - 0.004 17.1 0.0 0.069 13.2 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Abhydrolase_1 PF00561.20 EWM22862.1 - 2e-08 34.2 0.1 3e-08 33.6 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold CcmB PF03379.13 EWM22863.1 - 0.025 14.1 0.1 0.026 14.0 0.1 1.0 1 0 0 1 1 1 0 CcmB protein MORN PF02493.20 EWM22865.1 - 4.7e-28 95.4 30.2 2.2e-07 30.4 0.1 6.2 6 0 0 6 6 6 5 MORN repeat SAM_2 PF07647.17 EWM22865.1 - 0.0034 17.5 2.6 0.094 12.8 0.0 2.4 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) Pkinase PF00069.25 EWM22866.1 - 3.8e-50 170.7 0.0 4.8e-50 170.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM22866.1 - 2.2e-17 63.2 0.0 3.9e-17 62.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EWM22866.1 - 0.041 13.2 0.2 0.065 12.6 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EWM22866.1 - 0.11 11.4 0.0 0.23 10.4 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 EWM22866.1 - 0.13 11.0 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Clathrin PF00637.20 EWM22867.1 - 2e-08 34.2 3.3 0.015 15.1 0.1 4.2 4 0 0 4 4 4 3 Region in Clathrin and VPS TPR_2 PF07719.17 EWM22867.1 - 0.0013 18.6 28.3 0.23 11.6 0.3 7.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 EWM22867.1 - 0.0028 17.4 8.0 2.4 8.1 0.0 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat Chromosome_seg PF13889.6 EWM22867.1 - 0.02 15.1 0.0 0.046 13.9 0.0 1.5 1 0 0 1 1 1 0 Chromosome segregation during meiosis TPR_7 PF13176.6 EWM22867.1 - 0.094 12.8 10.0 8.2 6.7 0.1 5.3 3 1 1 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 EWM22867.1 - 2.8 8.4 14.1 3.4 8.1 0.4 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 EWM22867.1 - 6.6 7.1 28.3 0.054 13.8 1.4 5.6 3 2 3 6 6 6 0 Tetratricopeptide repeat MFS_1 PF07690.16 EWM22869.1 - 0.00094 18.2 9.2 0.0011 17.9 9.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CLPTM1 PF05602.12 EWM22870.1 - 0.21 10.6 0.0 0.25 10.3 0.0 1.0 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) SUIM_assoc PF16619.5 EWM22871.1 - 0.25 11.4 5.8 0.68 10.0 5.8 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 BACK PF07707.15 EWM22873.1 - 3e-07 30.5 0.4 2.6e-05 24.3 0.1 2.1 2 0 0 2 2 2 2 BTB And C-terminal Kelch BTB PF00651.31 EWM22873.1 - 0.00033 20.9 0.1 0.51 10.6 0.0 2.3 1 1 1 2 2 2 2 BTB/POZ domain WW PF00397.26 EWM22876.1 - 4.8e-05 23.4 6.3 0.00014 21.9 6.3 1.9 1 0 0 1 1 1 1 WW domain Clr2 PF10383.9 EWM22876.1 - 0.096 13.5 3.3 0.5 11.1 1.5 2.3 1 1 1 2 2 2 0 Transcription-silencing protein Clr2 TFIIA PF03153.13 EWM22876.1 - 7.7 6.4 22.7 9.5 6.1 22.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WW PF00397.26 EWM22877.1 - 3.3e-05 23.9 6.3 0.00011 22.2 6.3 2.0 1 0 0 1 1 1 1 WW domain Clr2 PF10383.9 EWM22877.1 - 0.058 14.2 3.6 0.35 11.7 1.5 2.3 1 1 1 2 2 2 0 Transcription-silencing protein Clr2 TFIIA PF03153.13 EWM22877.1 - 8.3 6.3 23.6 9.8 6.1 23.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_C65 PF10275.9 EWM22878.1 - 5.6e-56 189.7 0.0 2.1e-55 187.9 0.0 1.7 1 1 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 EWM22878.1 - 0.035 14.6 0.0 0.99 9.9 0.0 2.4 2 0 0 2 2 2 0 OTU-like cysteine protease Peptidase_C65 PF10275.9 EWM22879.1 - 5.6e-56 189.7 0.0 2.1e-55 187.9 0.0 1.7 1 1 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 EWM22879.1 - 0.035 14.6 0.0 0.99 9.9 0.0 2.4 2 0 0 2 2 2 0 OTU-like cysteine protease AAA_lid_3 PF17862.1 EWM22880.1 - 6.1e-10 38.8 0.1 9.9e-10 38.1 0.1 1.3 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 EWM22880.1 - 1.1e-08 35.6 0.1 4.9e-08 33.5 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 EWM22881.1 - 8.2e-34 116.9 0.0 2.2e-33 115.5 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EWM22881.1 - 3.1e-15 56.5 0.0 7e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EWM22881.1 - 5.7e-06 26.4 0.0 1e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EWM22881.1 - 0.008 16.5 0.1 0.052 13.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain NOA36 PF06524.12 EWM22881.1 - 4 6.7 6.3 6.3 6.0 6.3 1.3 1 0 0 1 1 1 0 NOA36 protein ERCC3_RAD25_C PF16203.5 EWM22883.1 - 2.5e-10 40.0 0.3 2.9e-10 39.8 0.3 1.1 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase UCH PF00443.29 EWM22884.1 - 1.9e-21 76.7 0.0 1.9e-21 76.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EWM22884.1 - 9.3e-07 28.7 0.0 1.3e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L23eN PF03939.13 EWM22885.1 - 0.093 13.0 0.5 0.19 12.0 0.5 1.5 1 0 0 1 1 1 0 Ribosomal protein L23, N-terminal domain Vps51 PF08700.11 EWM22886.1 - 3.4e-08 33.4 0.1 1.2e-07 31.7 0.1 1.9 1 0 0 1 1 1 1 Vps51/Vps67 DNA_RNApol_7kD PF03604.13 EWM22887.1 - 3.8e-15 55.2 5.6 7.8e-15 54.3 5.6 1.6 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit MCM_OB PF17207.3 EWM22887.1 - 0.054 13.3 1.1 0.054 13.3 1.1 1.8 2 0 0 2 2 2 0 MCM OB domain DZR PF12773.7 EWM22887.1 - 0.13 12.3 3.7 0.24 11.5 3.7 1.5 1 0 0 1 1 1 0 Double zinc ribbon bZIP_1 PF00170.21 EWM22888.1 - 0.00051 20.1 9.0 0.001 19.2 9.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EWM22888.1 - 0.046 13.8 9.7 0.11 12.6 9.7 1.6 1 0 0 1 1 1 0 Basic region leucine zipper ERCC3_RAD25_C PF16203.5 EWM22889.1 - 7e-79 264.5 0.0 1e-78 264.0 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 EWM22889.1 - 2e-30 105.5 0.0 4.2e-30 104.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EWM22889.1 - 4.1e-16 59.4 0.0 1.3e-15 57.8 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EWM22889.1 - 5.2e-12 46.1 0.4 1.8e-11 44.4 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EWM22889.1 - 1.4e-06 27.3 0.0 1.8e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 EWM22889.1 - 0.0011 18.8 0.1 0.0019 18.0 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EWM22889.1 - 0.0085 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase L6_membrane PF05805.12 EWM22889.1 - 0.017 14.7 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 L6 membrane protein Terpene_synth PF01397.21 EWM22889.1 - 0.11 12.2 0.1 0.28 10.8 0.1 1.6 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain PPR_2 PF13041.6 EWM22890.1 - 1.1e-89 294.5 3.0 2.1e-11 43.8 0.0 18.0 10 5 8 19 19 19 13 PPR repeat family PPR_3 PF13812.6 EWM22890.1 - 1.4e-63 210.8 0.0 1.8e-07 31.1 0.0 13.1 4 4 4 13 13 13 11 Pentatricopeptide repeat domain PPR PF01535.20 EWM22890.1 - 9.6e-58 188.5 34.7 9.2e-06 25.6 0.0 21.5 23 0 0 23 23 23 10 PPR repeat PPR_1 PF12854.7 EWM22890.1 - 3.6e-36 122.6 9.4 3.6e-05 23.4 0.0 13.9 15 0 0 15 15 15 7 PPR repeat PPR_long PF17177.4 EWM22890.1 - 8.4e-35 120.1 3.1 4.6e-09 35.9 0.0 7.9 6 2 1 8 8 8 4 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 EWM22890.1 - 0.00098 19.6 4.6 7.3 7.2 0.0 6.0 5 0 0 5 5 5 1 Tetratricopeptide repeat COX5A PF02284.16 EWM22890.1 - 0.012 15.6 0.1 55 3.8 0.0 4.0 3 1 1 4 4 4 0 Cytochrome c oxidase subunit Va BKACE PF05853.12 EWM22890.1 - 0.013 14.8 0.2 2.2 7.5 0.0 3.8 4 0 0 4 4 4 0 beta-keto acid cleavage enzyme HrpB1_HrpK PF09613.10 EWM22890.1 - 0.017 14.7 11.0 0.6 9.8 0.0 5.8 6 1 1 7 7 7 0 Bacterial type III secretion protein (HrpB1_HrpK) MRP-S27 PF10037.9 EWM22890.1 - 0.024 13.5 0.0 0.42 9.4 0.0 2.5 1 1 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 TPR_14 PF13428.6 EWM22890.1 - 1.6 9.8 22.4 6.3 7.9 0.1 8.2 10 1 1 11 11 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 EWM22890.1 - 8.4 6.8 12.1 3.4 8.0 0.4 5.0 7 0 0 7 7 6 0 Tetratricopeptide repeat UPF0004 PF00919.20 EWM22891.1 - 7.7e-17 61.2 0.0 1.5e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 EWM22891.1 - 1.2e-16 61.5 0.0 1.9e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Sugar_tr PF00083.24 EWM22892.1 - 9e-126 420.3 21.7 1.1e-125 420.1 21.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EWM22892.1 - 2.2e-32 112.4 27.7 2.2e-32 112.4 27.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EWM22892.1 - 0.0026 16.3 1.3 0.0044 15.5 1.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TruB_C PF09142.11 EWM22893.1 - 0.05 13.4 0.0 0.079 12.8 0.0 1.2 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal Lysis_col PF02402.16 EWM22893.1 - 0.26 11.0 0.4 0.26 11.0 0.4 1.9 2 0 0 2 2 2 0 Lysis protein Nudix_hydro PF18290.1 EWM22895.1 - 2.5e-29 101.1 0.0 3.9e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Nudix hydrolase domain NUDIX PF00293.28 EWM22895.1 - 3.3e-18 66.0 0.0 5.6e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Sugar_tr PF00083.24 EWM22896.1 - 5.2e-18 65.1 2.3 8.6e-18 64.4 2.3 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EWM22896.1 - 5.3e-07 28.9 16.7 1.6e-06 27.3 16.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Ubiq_cyt_C_chap PF03981.12 EWM22898.1 - 0.00024 21.2 0.1 0.00036 20.6 0.1 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone WW PF00397.26 EWM22899.1 - 1.3e-08 34.8 1.4 1.3e-08 34.8 1.4 1.7 2 0 0 2 2 2 1 WW domain Ig_5 PF16681.5 EWM22904.1 - 0.035 14.5 0.1 0.066 13.6 0.1 1.4 1 0 0 1 1 1 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain DLEU7 PF15760.5 EWM22906.1 - 4.6 6.7 6.1 7.5 6.0 6.1 1.3 1 0 0 1 1 1 0 Leukemia-associated protein 7 HGTP_anticodon PF03129.20 EWM22912.1 - 0.087 13.0 0.3 0.14 12.3 0.3 1.3 1 0 0 1 1 1 0 Anticodon binding domain SRP-alpha_N PF04086.13 EWM22912.1 - 0.65 9.9 9.6 0.82 9.5 9.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Importin_rep PF18773.1 EWM22913.1 - 0.21 11.3 0.1 0.35 10.6 0.1 1.3 1 0 0 1 1 1 0 Importin 13 repeat Kinesin PF00225.23 EWM22915.1 - 2.6e-96 322.5 0.0 3.2e-96 322.1 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EWM22915.1 - 1.3e-19 70.6 0.0 2.2e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding Dus PF01207.17 EWM22921.1 - 5e-17 61.9 0.0 6.3e-17 61.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Mito_fiss_reg PF05308.11 EWM22923.1 - 1.4 8.9 4.4 1.4 8.9 4.4 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EWM22923.1 - 1.6 8.2 6.7 1.5 8.2 6.7 1.0 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SOUL PF04832.12 EWM22925.1 - 5.7e-12 46.1 0.0 6.3e-12 46.0 0.0 1.0 1 0 0 1 1 1 1 SOUL heme-binding protein PP-binding PF00550.25 EWM22928.1 - 0.0079 16.5 0.0 0.013 15.8 0.0 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site Phage_int_SAM_1 PF02899.17 EWM22929.1 - 0.0043 17.3 0.1 0.0063 16.8 0.1 1.2 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain DUF3486 PF11985.8 EWM22929.1 - 0.0058 17.1 0.0 0.0073 16.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3486) XH PF03469.14 EWM22930.1 - 2.6e-08 33.8 0.0 5.6e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 XH domain FA_hydroxylase PF04116.13 EWM22932.1 - 4.8e-18 65.8 16.1 4.8e-18 65.8 16.1 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF4168 PF13767.6 EWM22934.1 - 9.2e-21 74.8 0.0 2.8e-10 41.2 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4168) CCDC24 PF15669.5 EWM22937.1 - 0.25 11.2 0.0 0.34 10.7 0.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Iso_dh PF00180.20 EWM22938.1 - 4.6e-124 414.1 0.0 5.3e-124 413.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PPR_long PF17177.4 EWM22939.1 - 8.9e-09 35.0 0.6 1.2e-08 34.5 0.6 1.2 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 EWM22939.1 - 1.3e-08 34.5 0.0 0.016 15.4 0.0 4.0 4 0 0 4 4 4 2 PPR repeat PPR_2 PF13041.6 EWM22939.1 - 3.8e-08 33.4 0.0 0.043 14.0 0.0 3.9 3 1 1 4 4 4 3 PPR repeat family PPR_3 PF13812.6 EWM22939.1 - 1.5e-07 31.4 0.0 0.054 13.6 0.0 3.9 2 1 2 4 4 4 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 EWM22939.1 - 0.0018 18.0 0.5 0.87 9.3 0.0 3.1 3 0 0 3 3 3 1 PPR repeat TPR_14 PF13428.6 EWM22939.1 - 0.0024 18.6 6.3 0.43 11.5 0.1 3.8 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 EWM22939.1 - 0.0059 17.1 0.1 3.3 8.6 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EWM22939.1 - 0.007 16.6 1.7 0.083 13.2 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EWM22939.1 - 0.02 15.0 3.5 0.17 12.1 0.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.17 EWM22939.1 - 0.032 14.7 0.5 0.19 12.1 0.0 2.4 2 1 0 3 3 3 0 Bacterial transcriptional activator domain TPR_7 PF13176.6 EWM22939.1 - 0.062 13.4 0.9 0.58 10.3 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EWM22939.1 - 0.17 12.4 4.2 3.2 8.3 0.7 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EWM22939.1 - 0.17 11.7 3.5 0.54 10.2 0.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EWM22939.1 - 0.23 11.4 0.9 0.81 9.6 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 EWM22939.1 - 0.41 11.3 5.8 1.8 9.3 0.8 3.2 3 1 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EWM22939.1 - 2.4 9.0 4.5 21 6.0 0.1 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat Metallophos PF00149.28 EWM22940.1 - 1.7e-19 71.1 0.0 3.4e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_7 PF13499.6 EWM22941.1 - 9.2e-13 48.4 3.6 3.9e-08 33.6 0.7 2.6 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EWM22941.1 - 7.4e-12 43.9 2.3 8.1e-07 28.2 0.1 2.7 2 1 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EWM22941.1 - 4.8e-09 35.4 1.6 4e-05 23.2 0.1 3.1 2 1 1 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 EWM22941.1 - 1.2e-07 31.5 2.9 0.00023 20.9 0.1 2.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EWM22941.1 - 4.8e-07 29.0 3.4 1.1e-06 27.9 0.1 2.8 2 1 1 3 3 3 1 EF hand EF-hand_4 PF12763.7 EWM22941.1 - 0.0034 17.3 0.1 0.076 13.0 0.0 2.1 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 EWM22941.1 - 0.17 11.8 0.0 0.75 9.7 0.0 1.8 2 0 0 2 2 2 0 Caleosin related protein Utp12 PF04003.12 EWM22942.1 - 7.5e-12 45.5 2.1 1.3e-11 44.8 2.1 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.32 EWM22942.1 - 3.9e-06 27.5 0.0 0.00048 20.9 0.0 2.4 2 0 0 2 2 2 1 WD domain, G-beta repeat WSD PF15613.6 EWM22942.1 - 0.026 15.0 0.4 0.04 14.4 0.4 1.3 1 0 0 1 1 1 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif HECT PF00632.25 EWM22943.1 - 7.6e-48 163.6 0.0 1.1e-47 163.1 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) MIB_HERC2 PF06701.13 EWM22943.1 - 7.3e-08 32.5 2.0 7.7e-06 26.1 0.0 3.0 2 0 0 2 2 2 1 Mib_herc2 SPRY PF00622.28 EWM22943.1 - 1.3e-05 25.3 0.0 4.2e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 SPRY domain Presenilin PF01080.17 EWM22943.1 - 0.017 13.9 14.3 0.023 13.5 14.3 1.1 1 0 0 1 1 1 0 Presenilin DDHD PF02862.17 EWM22943.1 - 0.98 9.5 2.8 2.3 8.3 2.8 1.6 1 0 0 1 1 1 0 DDHD domain AAA_11 PF13086.6 EWM22944.1 - 1.3e-60 205.4 0.0 3.9e-60 203.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_12 PF13087.6 EWM22944.1 - 3.5e-49 167.2 0.0 5.7e-49 166.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EWM22944.1 - 3.1e-15 56.4 7.2 6.9e-11 42.2 0.0 3.8 3 1 1 4 4 3 2 AAA domain AAA_19 PF13245.6 EWM22944.1 - 3.2e-10 40.5 0.6 3.1e-08 34.1 0.3 3.4 2 1 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 EWM22944.1 - 2.8e-06 27.3 0.0 0.00044 20.1 0.0 2.8 3 0 0 3 3 3 1 Helicase AAA_22 PF13401.6 EWM22944.1 - 3.3e-06 27.4 0.0 0.00035 20.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EWM22944.1 - 1.1e-05 25.3 0.0 0.19 11.5 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 EWM22944.1 - 4.6e-05 23.3 0.1 0.00023 21.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_25 PF13481.6 EWM22944.1 - 0.00046 19.8 0.2 0.029 14.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 EWM22944.1 - 0.00071 19.1 0.0 0.016 14.7 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein UvrD-helicase PF00580.21 EWM22944.1 - 0.00089 18.9 0.0 0.002 17.7 0.0 1.6 2 0 0 2 2 1 1 UvrD/REP helicase N-terminal domain PIF1 PF05970.14 EWM22944.1 - 0.0017 17.6 0.0 0.68 9.0 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase UvrD_C_2 PF13538.6 EWM22944.1 - 0.0019 18.0 0.0 0.0046 16.8 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF2075 PF09848.9 EWM22944.1 - 0.0024 17.2 0.0 0.11 11.7 0.0 2.4 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 EWM22944.1 - 0.0024 18.3 2.9 0.0026 18.1 0.4 2.4 2 1 0 2 2 2 1 AAA ATPase domain Flavi_DEAD PF07652.14 EWM22944.1 - 0.003 17.5 0.2 0.0077 16.2 0.1 1.7 2 0 0 2 2 1 1 Flavivirus DEAD domain ResIII PF04851.15 EWM22944.1 - 0.0062 16.6 0.0 0.051 13.6 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 EWM22944.1 - 0.0065 15.4 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.29 EWM22944.1 - 0.013 16.0 0.0 0.029 14.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 EWM22944.1 - 0.022 14.1 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.6 EWM22944.1 - 0.065 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zot PF05707.12 EWM22944.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) NACHT PF05729.12 EWM22944.1 - 0.12 12.3 0.0 0.38 10.6 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Herpes_ori_bp PF02399.15 EWM22944.1 - 0.13 10.2 0.0 0.19 9.7 0.0 1.1 1 0 0 1 1 1 0 Origin of replication binding protein AAA_5 PF07728.14 EWM22944.1 - 0.14 12.1 0.0 0.44 10.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 EWM22944.1 - 0.17 11.8 0.3 1.9 8.4 0.0 2.2 2 0 0 2 2 2 0 NTPase Rad17 PF03215.15 EWM22944.1 - 0.27 11.1 0.0 0.47 10.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain IDO PF01231.18 EWM22945.1 - 7e-70 236.0 0.0 4.3e-67 226.8 0.0 2.7 1 1 1 2 2 2 2 Indoleamine 2,3-dioxygenase RIO1 PF01163.22 EWM22947.1 - 8e-73 244.1 0.0 1.9e-72 242.8 0.0 1.7 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EWM22947.1 - 7.1e-06 26.1 4.4 0.011 15.7 0.1 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 EWM22947.1 - 4.9e-05 22.8 0.5 0.29 10.4 0.2 2.7 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EWM22947.1 - 0.043 12.6 0.0 0.043 12.6 0.0 2.7 2 1 0 2 2 2 0 Fungal protein kinase Rhabdo_ncap PF00945.18 EWM22947.1 - 7.1 5.4 8.6 16 4.3 8.6 1.5 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Glycos_transf_2 PF00535.26 EWM22948.1 - 0.079 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 MEDS PF14417.6 EWM22948.1 - 0.087 12.7 0.0 0.28 11.0 0.0 1.8 2 0 0 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain SPA PF08616.10 EWM22950.1 - 3.1e-20 72.2 0.0 6.3e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 EWM22950.1 - 6.8e-12 46.0 0.0 1.1e-11 45.3 0.0 1.3 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2347 PF09804.9 EWM22950.1 - 1.3e-07 31.5 0.0 0.00012 21.8 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.9 EWM22950.1 - 0.00017 20.4 0.0 2.5 6.7 0.0 3.1 2 1 1 3 3 3 3 Transport protein Avl9 Myb_DNA-binding PF00249.31 EWM22951.1 - 1.1e-36 124.8 16.1 3.6e-14 52.7 0.4 4.1 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EWM22951.1 - 9.3e-31 105.9 7.2 4.8e-12 45.9 0.1 3.7 3 1 1 4 4 4 3 Myb-like DNA-binding domain Rap1_C PF11626.8 EWM22951.1 - 0.011 15.7 5.6 15 5.8 0.7 4.0 2 1 1 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 EWM22951.1 - 0.044 13.7 0.1 0.98 9.4 0.0 2.4 2 0 0 2 2 2 0 Myb DNA-binding like DUF1151 PF06625.11 EWM22951.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) Myb_DNA-binding PF00249.31 EWM22952.1 - 3.9e-37 126.2 16.1 2.7e-14 53.1 0.4 4.1 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EWM22952.1 - 5.1e-31 106.7 7.5 3.6e-12 46.3 0.1 3.7 3 1 1 4 4 4 3 Myb-like DNA-binding domain Rap1_C PF11626.8 EWM22952.1 - 0.016 15.3 7.0 11 6.2 0.1 4.0 2 1 2 4 4 4 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 EWM22952.1 - 0.028 14.3 0.2 0.71 9.8 0.1 2.4 2 0 0 2 2 2 0 Myb DNA-binding like DUF1151 PF06625.11 EWM22952.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) DUF2358 PF10184.9 EWM22953.1 - 3e-11 43.6 0.0 4.1e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) DEAD PF00270.29 EWM22954.1 - 2.2e-44 151.3 0.1 4.2e-44 150.4 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EWM22954.1 - 1e-31 109.6 0.2 5.4e-31 107.2 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EWM22954.1 - 2.4e-05 24.4 0.0 4.4e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EWM22954.1 - 0.00014 22.2 0.1 0.0012 19.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EWM22954.1 - 0.00022 21.0 0.1 0.00037 20.3 0.1 1.3 1 0 0 1 1 1 1 AAA domain CMS1 PF14617.6 EWM22954.1 - 0.013 14.8 0.1 0.034 13.5 0.0 1.6 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Fanconi_A PF03511.14 EWM22954.1 - 0.015 15.2 0.0 0.37 10.7 0.0 2.4 2 0 0 2 2 2 0 Fanconi anaemia group A protein UvrD-helicase PF00580.21 EWM22954.1 - 0.087 12.3 0.2 0.22 11.0 0.2 1.3 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 EWM22954.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.6 EWM22954.1 - 0.16 12.2 0.3 1.2 9.4 0.3 2.3 1 1 0 1 1 1 0 AAA domain PhyH PF05721.13 EWM22955.1 - 0.00038 20.8 0.1 1.3 9.2 0.1 2.9 2 1 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 EWM22955.1 - 0.012 14.5 0.0 0.11 11.2 0.0 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1479) WD40 PF00400.32 EWM22956.1 - 5.5e-21 74.5 17.9 4.9e-06 27.2 0.8 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.12 EWM22956.1 - 5.3e-15 55.7 0.0 8.1e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain ANAPC4_WD40 PF12894.7 EWM22956.1 - 3.9e-08 33.5 1.1 0.026 14.8 0.0 3.6 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EWM22956.1 - 9.2e-06 24.6 2.2 0.087 11.5 0.0 3.3 2 1 2 4 4 4 2 Nucleoporin Nup120/160 ELYS-bb PF16687.5 EWM22956.1 - 0.073 11.7 0.0 4.5 5.8 0.0 2.1 1 1 1 2 2 2 0 beta-propeller of ELYS nucleoporin Glutaredoxin PF00462.24 EWM22957.1 - 1.4e-20 73.2 0.0 2.1e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF656 PF04920.12 EWM22957.1 - 0.14 12.0 0.1 0.21 11.5 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF656) Malate_synthase PF01274.22 EWM22958.1 - 4.2e-183 609.4 0.0 5.1e-183 609.1 0.0 1.0 1 0 0 1 1 1 1 Malate synthase DUF5522 PF17653.1 EWM22960.1 - 1.4e-23 82.5 3.2 2.3e-23 81.9 3.2 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5522) SOG2 PF10428.9 EWM22961.1 - 1.8 7.6 10.1 2.2 7.4 10.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4460 PF14687.6 EWM22962.1 - 3.5e-18 65.6 0.0 4.8e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4460) Pkinase PF00069.25 EWM22963.1 - 2.1e-53 181.4 0.0 3.4e-53 180.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM22963.1 - 7.2e-37 127.1 0.0 1.1e-36 126.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 EWM22963.1 - 1.9e-07 31.2 0.6 5.2e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 Oxidative-stress-responsive kinase 1 C-terminal domain Rep_3 PF01051.21 EWM22963.1 - 1.2 8.9 4.3 1.8 8.3 4.3 1.2 1 0 0 1 1 1 0 Initiator Replication protein HSP70 PF00012.20 EWM22964.1 - 6.8e-256 850.2 9.7 1.3e-155 519.0 4.4 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EWM22964.1 - 7.7e-11 41.4 0.7 2.1e-05 23.5 0.1 3.0 3 0 0 3 3 3 2 MreB/Mbl protein PKK PF12474.8 EWM22964.1 - 2.1 8.5 12.2 0.19 11.8 5.7 2.0 2 0 0 2 2 2 0 Polo kinase kinase FAD_binding_4 PF01565.23 EWM22966.1 - 2.5e-10 40.2 0.0 4.5e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 EWM22966.1 - 0.0066 16.3 0.1 0.011 15.6 0.1 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase Exonuc_VII_S PF02609.16 EWM22967.1 - 0.027 14.5 0.2 0.093 12.8 0.0 2.0 2 0 0 2 2 2 0 Exonuclease VII small subunit PKcGMP_CC PF16808.5 EWM22967.1 - 0.12 12.3 3.0 0.23 11.4 0.3 2.7 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase HAP1_N PF04849.13 EWM22967.1 - 0.35 10.0 10.1 0.24 10.5 0.7 2.9 3 0 0 3 3 3 0 HAP1 N-terminal conserved region DUF641 PF04859.12 EWM22967.1 - 0.85 10.0 9.9 2.2 8.6 0.2 3.3 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) ABC_tran_CTD PF16326.5 EWM22967.1 - 1.4 9.3 13.2 13 6.1 2.5 3.6 3 0 0 3 3 3 0 ABC transporter C-terminal domain Cortex-I_coil PF09304.10 EWM22967.1 - 2.8 8.2 16.6 0.096 12.9 3.0 3.2 3 1 0 3 3 3 0 Cortexillin I, coiled coil GAS PF13851.6 EWM22967.1 - 3.9 6.8 13.3 4.9 6.4 1.9 3.1 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Exonuc_VII_L PF02601.15 EWM22967.1 - 6.9 6.1 9.4 1.8e+02 1.5 9.2 2.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF4140 PF13600.6 EWM22967.1 - 8.6 6.9 12.5 42 4.7 0.5 3.8 3 1 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) Rab5-bind PF09311.11 EWM22967.1 - 9.4 5.5 10.9 3.6 6.9 0.1 3.1 3 0 0 3 3 3 0 Rabaptin-like protein APG17 PF04108.12 EWM22969.1 - 3.7e-27 95.5 2.0 2.1e-24 86.4 2.0 2.5 1 1 0 1 1 1 1 Autophagy protein Apg17 WXG100 PF06013.12 EWM22969.1 - 0.14 12.4 3.9 17 5.7 0.1 3.8 3 1 0 3 3 3 0 Proteins of 100 residues with WXG EzrA PF06160.12 EWM22969.1 - 0.16 10.1 0.3 0.27 9.4 0.3 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA GAS PF13851.6 EWM22969.1 - 0.65 9.3 4.9 0.27 10.6 1.9 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Pkinase PF00069.25 EWM22970.1 - 4.7e-32 111.4 0.0 4.9e-31 108.1 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM22970.1 - 1.7e-19 70.1 0.0 7.8e-19 68.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EWM22970.1 - 0.00022 20.6 0.0 0.00043 19.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EWM22970.1 - 0.011 14.5 0.0 0.026 13.3 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EWM22970.1 - 0.029 13.7 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-PARP PF00645.18 EWM22971.1 - 0.0025 18.7 0.0 0.0087 16.9 0.0 2.0 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region PALP PF00291.25 EWM22973.1 - 0.017 14.6 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme RCDG1 PF15725.5 EWM22974.1 - 0.078 13.4 0.6 0.078 13.4 0.6 3.6 3 0 0 3 3 3 0 Renal cancer differentiation gene 1 protein PALP PF00291.25 EWM22975.1 - 2.8e-40 138.6 0.2 3.2e-40 138.4 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme adh_short_C2 PF13561.6 EWM22978.1 - 0.053 13.1 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase TAFII28 PF04719.14 EWM22979.1 - 9.9e-07 28.8 0.6 1.4e-06 28.3 0.6 1.2 1 0 0 1 1 1 1 hTAFII28-like protein conserved region Pro_isomerase PF00160.21 EWM22980.1 - 1.4e-37 129.4 0.1 1.4e-37 129.4 0.1 2.1 2 1 1 3 3 3 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF913 PF06025.12 EWM22980.1 - 8.1 5.3 6.3 14 4.5 6.3 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) adh_short_C2 PF13561.6 EWM22981.1 - 8.4e-31 107.3 0.1 1e-30 107.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ATP-synt PF00231.19 EWM22982.1 - 6.9e-17 62.1 0.1 7.9e-17 61.9 0.1 1.1 1 0 0 1 1 1 1 ATP synthase WD40 PF00400.32 EWM22983.1 - 0.00035 21.3 0.1 0.014 16.3 0.0 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM22983.1 - 0.0047 17.2 0.2 0.0082 16.4 0.2 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain DUF547 PF04784.14 EWM22984.1 - 2.2e-25 89.0 0.0 3.2e-24 85.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF547 WD40 PF00400.32 EWM22985.1 - 7.1e-09 36.2 3.8 0.00064 20.5 0.5 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat PheRS_DBD3 PF18553.1 EWM22987.1 - 1.3e-14 54.2 0.5 1.1e-13 51.2 0.1 2.2 1 1 1 2 2 2 1 PheRS DNA binding domain 3 PheRS_DBD1 PF18552.1 EWM22987.1 - 5.8e-07 29.2 0.1 1.6e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 PheRS DNA binding domain 1 RQC PF09382.10 EWM22987.1 - 0.034 13.9 0.0 0.089 12.6 0.0 1.7 2 0 0 2 2 2 0 RQC domain HTH_27 PF13463.6 EWM22987.1 - 0.12 12.9 0.1 2.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Winged helix DNA-binding domain GAD PF02938.14 EWM22987.1 - 0.14 12.4 0.7 1.9 8.8 0.1 2.3 2 0 0 2 2 2 0 GAD domain CRT-like PF08627.10 EWM22988.1 - 2.5e-16 59.5 5.0 4.9e-16 58.6 5.0 1.5 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EFG_C PF00679.24 EWM22989.1 - 8.6e-26 89.8 0.0 1.2e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 EWM22989.1 - 8.9e-11 41.6 0.2 1.6e-10 40.8 0.2 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV tRNA-synt_2d PF01409.20 EWM22990.1 - 2.4e-56 191.0 0.0 2.9e-56 190.7 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA_synthFbeta PF17759.1 EWM22990.1 - 0.00011 21.7 0.0 0.00014 21.4 0.0 1.1 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 EWM22990.1 - 0.00017 20.8 0.0 0.00029 20.0 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 EWM22990.1 - 0.031 14.2 0.0 0.04 13.9 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) EFG_II PF14492.6 EWM22991.1 - 1e-31 108.8 0.0 1.5e-31 108.3 0.0 1.3 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 EWM22991.1 - 8.1e-10 39.0 0.0 1.5e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EWM22991.1 - 4.4e-09 36.3 0.0 6.3e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_IV PF03764.18 EWM22991.1 - 8.3e-05 22.4 0.1 0.00024 20.9 0.0 1.7 2 0 0 2 2 2 1 Elongation factor G, domain IV GTP_EFTU PF00009.27 EWM22993.1 - 4.2e-10 39.5 0.1 6.2e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Pribosyltran PF00156.27 EWM22995.1 - 8.7e-08 31.8 0.0 1.2e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain FUSC_2 PF13515.6 EWM22996.1 - 2.5e-11 43.8 12.6 4.1e-11 43.1 12.6 1.4 1 0 0 1 1 1 1 Fusaric acid resistance protein-like FUSC PF04632.12 EWM22996.1 - 2.3e-10 39.7 6.8 3.1e-10 39.3 6.8 1.1 1 0 0 1 1 1 1 Fusaric acid resistance protein family ALMT PF11744.8 EWM22996.1 - 7.9e-06 25.0 3.2 3e-05 23.1 3.2 1.7 1 1 0 1 1 1 1 Aluminium activated malate transporter IMPDH PF00478.25 EWM22998.1 - 0.00027 20.1 0.0 0.00033 19.8 0.0 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EWM23000.1 - 0.048 13.0 0.0 0.053 12.9 0.0 1.0 1 0 0 1 1 1 0 Nitronate monooxygenase AF-4 PF05110.13 EWM23003.1 - 0.23 9.5 7.2 0.26 9.3 7.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SR-25 PF10500.9 EWM23003.1 - 6.8 6.2 17.0 0.28 10.8 11.0 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein COA2 PF17051.5 EWM23005.1 - 0.02 15.0 0.1 0.18 11.9 0.0 2.0 2 0 0 2 2 2 0 Cytochrome C oxidase assembly factor 2 7TM_GPCR_Sri PF10327.9 EWM23010.1 - 0.088 12.0 0.1 0.13 11.4 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri DUF962 PF06127.11 EWM23011.1 - 3e-19 68.9 9.2 3.2e-19 68.8 5.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF962) FoP_duplication PF13865.6 EWM23013.1 - 1.1 9.9 10.0 1.3 9.6 10.0 1.1 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 DUF1168 PF06658.12 EWM23014.1 - 0.11 12.3 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Glyco_hydro_6 PF01341.17 EWM23015.1 - 0.06 13.1 0.0 0.06 13.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 6 zf-C2H2 PF00096.26 EWM23016.1 - 0.0065 16.9 0.0 0.02 15.3 0.0 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EWM23016.1 - 0.049 14.5 0.0 0.17 12.8 0.0 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger Cyt-b5 PF00173.28 EWM23019.1 - 2.5e-12 46.7 0.0 3.7e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SR-25 PF10500.9 EWM23020.1 - 0.17 11.5 5.1 0.21 11.2 5.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PLA2_B PF01735.18 EWM23023.1 - 3.6e-25 88.3 8.8 7.4e-11 41.1 0.0 3.7 3 1 0 3 3 3 3 Lysophospholipase catalytic domain Patatin PF01734.22 EWM23023.1 - 0.0032 17.7 5.6 0.017 15.3 3.4 3.0 2 1 0 2 2 2 1 Patatin-like phospholipase Phage_Mu_Gam PF07352.12 EWM23030.1 - 0.0062 16.5 12.7 0.041 13.8 5.4 2.2 1 1 1 2 2 2 2 Bacteriophage Mu Gam like protein HIP1_clath_bdg PF16515.5 EWM23030.1 - 0.051 14.2 10.3 0.68 10.6 4.0 2.1 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1640 PF07798.11 EWM23030.1 - 0.15 12.1 9.2 0.75 9.8 8.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF1451 PF07295.11 EWM23030.1 - 0.25 11.4 5.0 0.37 10.8 4.6 1.4 1 1 0 1 1 1 0 Zinc-ribbon containing domain Prominin PF05478.11 EWM23030.1 - 0.26 9.2 1.1 0.29 9.0 1.1 1.1 1 0 0 1 1 1 0 Prominin DUF1690 PF07956.11 EWM23030.1 - 0.49 10.8 9.0 0.8 10.1 9.0 1.4 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) ATP-synt_B PF00430.18 EWM23030.1 - 1.5 8.9 17.6 4.7 7.3 3.8 2.4 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Phage_Mu_Gam PF07352.12 EWM23032.1 - 0.011 15.6 10.4 0.038 13.9 2.1 2.4 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein DUF1690 PF07956.11 EWM23032.1 - 0.057 13.8 14.6 0.1 13.0 7.9 2.0 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) CAF-1_p150 PF11600.8 EWM23032.1 - 0.083 12.6 12.6 0.11 12.2 12.6 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3010 PF11215.8 EWM23032.1 - 0.11 12.9 4.1 0.5 10.7 0.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3010) Prominin PF05478.11 EWM23032.1 - 0.27 9.1 2.1 0.31 9.0 2.1 1.1 1 0 0 1 1 1 0 Prominin His_Me_b4a2 PF18275.1 EWM23032.1 - 0.34 11.0 1.8 8.2 6.6 0.0 3.0 3 0 0 3 3 3 0 His-Me finger endonuclease beta4-alpha2 domain DAP_B PF07930.12 EWM23032.1 - 0.4 10.6 6.5 1.9 8.5 0.8 2.2 1 1 1 2 2 2 0 D-aminopeptidase, domain B HIP1_clath_bdg PF16515.5 EWM23032.1 - 3.1 8.5 12.1 21 5.8 4.2 2.4 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Phage_Mu_Gam PF07352.12 EWM23033.1 - 0.031 14.2 11.2 0.23 11.3 4.6 2.4 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein CAF-1_p150 PF11600.8 EWM23033.1 - 0.036 13.8 14.5 0.046 13.4 14.5 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DAP_B PF07930.12 EWM23033.1 - 0.4 10.6 5.6 1.3 9.0 3.8 2.2 1 1 1 2 2 2 0 D-aminopeptidase, domain B HIP1_clath_bdg PF16515.5 EWM23033.1 - 0.5 11.0 12.6 2 9.1 3.1 2.2 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1690 PF07956.11 EWM23033.1 - 1.6 9.1 10.3 1.8 9.0 9.4 1.4 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) Glyoxalase PF00903.25 EWM23035.1 - 4.1e-09 36.7 0.0 6e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF3081 PF11280.8 EWM23035.1 - 0.038 13.8 0.0 0.088 12.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3081) Glyoxalase_6 PF18029.1 EWM23035.1 - 0.05 14.4 0.0 0.09 13.6 0.0 1.5 1 1 0 1 1 1 0 Glyoxalase-like domain Nuc_sug_transp PF04142.15 EWM23038.1 - 6.1e-22 78.2 3.6 8e-22 77.8 3.6 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter PUNUT PF16913.5 EWM23038.1 - 0.00019 20.8 6.7 0.00028 20.2 6.7 1.2 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport Glyoxalase PF00903.25 EWM23040.1 - 0.044 14.0 0.0 0.09 13.0 0.0 1.5 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Tropomodulin PF03250.14 EWM23040.1 - 0.11 12.5 0.1 0.25 11.4 0.1 1.6 1 1 1 2 2 2 0 Tropomodulin DRMBL PF07522.14 EWM23043.1 - 9.9e-14 51.5 0.0 1.7e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase RMMBL PF07521.12 EWM23043.1 - 9.9e-06 25.4 0.0 7.5e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 EWM23043.1 - 2.4e-05 23.9 0.0 4.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EWM23043.1 - 0.012 15.6 0.1 0.04 13.9 0.0 1.8 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily CAP_N PF01213.19 EWM23044.1 - 0.6 9.5 5.5 1.6 8.1 0.3 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF4404 PF14357.6 EWM23045.1 - 0.78 10.4 4.6 0.98 10.1 0.7 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) NEMO PF11577.8 EWM23045.1 - 2 8.5 6.4 1.8 8.6 3.9 2.1 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO RRM_1 PF00076.22 EWM23046.1 - 1e-18 66.9 0.1 7.4e-16 57.7 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EWM23046.1 - 0.0028 17.7 0.0 0.53 10.4 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif AMP-binding PF00501.28 EWM23049.1 - 2.6e-44 151.5 0.5 1.5e-37 129.2 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme RRM_1 PF00076.22 EWM23050.1 - 0.0014 18.4 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RhlB PF12300.8 EWM23050.1 - 0.12 12.5 8.8 0.14 12.3 8.8 1.2 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB RRM_7 PF16367.5 EWM23050.1 - 0.2 11.8 0.0 0.31 11.2 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif BCDHK_Adom3 PF10436.9 EWM23051.1 - 4.6e-31 107.9 0.0 7.4e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EWM23051.1 - 5.7e-06 26.8 0.0 2.4e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cupin_8 PF13621.6 EWM23052.1 - 1.9e-30 106.5 0.0 2.2e-18 66.9 0.0 2.1 2 0 0 2 2 2 2 Cupin-like domain Transket_pyr PF02779.24 EWM23053.1 - 0.071 12.8 0.1 0.098 12.3 0.1 1.2 1 0 0 1 1 1 0 Transketolase, pyrimidine binding domain SpoIIM PF01944.17 EWM23055.1 - 0.0031 17.6 0.7 0.0036 17.4 0.7 1.3 1 0 0 1 1 1 1 Stage II sporulation protein M WD40 PF00400.32 EWM23056.1 - 3.1e-06 27.8 0.1 0.21 12.5 0.1 2.7 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM23056.1 - 0.008 16.4 0.0 2 8.8 0.0 2.2 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain TFIIA PF03153.13 EWM23056.1 - 0.37 10.7 17.6 0.4 10.6 17.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cob_adeno_trans PF01923.18 EWM23057.1 - 6.4e-25 88.2 0.0 7e-25 88.1 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase Chon_Sulph_att PF06566.11 EWM23059.1 - 0.23 11.3 7.0 0.28 11.0 7.0 1.2 1 0 0 1 1 1 0 Chondroitin sulphate attachment domain Toxin_ToxA PF11584.8 EWM23060.1 - 0.07 13.1 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Proteinaceous host-selective toxin ToxA tRNA_anti-codon PF01336.25 EWM23061.1 - 0.024 14.6 0.2 0.043 13.8 0.2 1.5 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain Cdd1 PF11731.8 EWM23061.1 - 0.13 12.6 0.1 0.51 10.6 0.1 1.9 2 0 0 2 2 2 0 Pathogenicity locus CDC45 PF02724.14 EWM23064.1 - 0.038 12.3 2.7 0.046 12.0 2.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Voldacs PF03517.13 EWM23064.1 - 0.062 13.4 0.4 0.1 12.7 0.4 1.4 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling CDC27 PF09507.10 EWM23064.1 - 0.91 8.8 9.3 1.3 8.3 9.3 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Cnd2 PF05786.14 EWM23064.1 - 5.3 5.6 6.3 7 5.2 6.3 1.2 1 0 0 1 1 1 0 Condensin complex subunit 2 DUF5549 PF17703.1 EWM23065.1 - 0.092 12.4 2.5 2.4 7.8 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5549) zf-DNL PF05180.12 EWM23067.1 - 1.8e-26 91.8 0.1 3.4e-26 91.0 0.1 1.4 1 0 0 1 1 1 1 DNL zinc finger Atg8 PF02991.16 EWM23068.1 - 9.7e-33 112.5 0.1 1.5e-32 111.9 0.1 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 EWM23068.1 - 0.0028 18.0 0.0 0.0051 17.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Abhydrolase_1 PF00561.20 EWM23072.1 - 5.7e-08 32.7 0.0 8.7e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EWM23072.1 - 5.2e-07 30.5 2.2 6.8e-07 30.1 0.3 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydro_lipase PF04083.16 EWM23072.1 - 0.025 14.2 0.1 0.037 13.6 0.1 1.3 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region EHN PF06441.12 EWM23072.1 - 0.05 14.0 0.1 0.074 13.4 0.1 1.3 1 0 0 1 1 1 0 Epoxide hydrolase N terminus Hydrolase_4 PF12146.8 EWM23072.1 - 0.1 11.8 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 ribosomal_L24 PF17136.4 EWM23073.1 - 2.4e-17 63.1 0.1 7.4e-17 61.5 0.0 1.9 2 0 0 2 2 2 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 EWM23073.1 - 8.4e-08 31.9 1.0 1.9e-07 30.8 1.0 1.7 1 0 0 1 1 1 1 KOW motif DAO PF01266.24 EWM23074.1 - 8.9e-05 22.2 0.1 0.00015 21.5 0.0 1.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EWM23074.1 - 0.001 19.3 0.0 0.0018 18.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EWM23074.1 - 0.087 12.0 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HMA PF00403.26 EWM23077.1 - 9.9e-05 22.7 0.1 9.9e-05 22.7 0.1 1.7 2 0 0 2 2 2 1 Heavy-metal-associated domain Pyr_redox_2 PF07992.14 EWM23080.1 - 1.2e-12 47.7 0.0 1.2e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EWM23080.1 - 1e-07 31.4 2.9 1.4e-07 30.9 2.9 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EWM23080.1 - 3.2e-07 29.8 0.8 3.9e-07 29.5 0.8 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EWM23080.1 - 5.2e-06 26.1 1.2 6.3e-06 25.8 1.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EWM23080.1 - 8.6e-06 24.7 0.3 1e-05 24.5 0.3 1.1 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 EWM23080.1 - 5.1e-05 23.4 0.5 9.9e-05 22.5 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EWM23080.1 - 8.1e-05 22.0 0.2 0.00012 21.5 0.2 1.2 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 EWM23080.1 - 0.00033 20.0 0.0 0.00042 19.7 0.0 1.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 EWM23080.1 - 0.0011 18.6 0.9 0.0014 18.3 0.9 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EWM23080.1 - 0.038 13.2 0.0 0.049 12.9 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EWM23080.1 - 0.044 12.8 0.1 0.057 12.5 0.1 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 EWM23080.1 - 0.054 12.7 0.7 0.087 12.0 0.2 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 EWM23080.1 - 0.073 13.6 0.2 0.11 13.0 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 EWM23080.1 - 0.14 11.5 0.4 0.19 11.1 0.4 1.2 1 0 0 1 1 1 0 short chain dehydrogenase CAP_N PF01213.19 EWM23081.1 - 6.7 6.1 7.3 10 5.5 7.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Malic_M PF03949.15 EWM23084.1 - 1.5e-25 90.0 0.0 1.7e-25 89.8 0.0 1.0 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EWM23085.1 - 3e-38 131.4 0.0 5e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain MatE PF01554.18 EWM23087.1 - 3.4e-05 23.6 2.3 5e-05 23.0 2.3 1.3 1 0 0 1 1 1 1 MatE Ras PF00071.22 EWM23088.1 - 3.2e-45 153.6 0.0 4e-45 153.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EWM23088.1 - 1.9e-22 79.7 0.0 2.7e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EWM23088.1 - 1e-06 28.3 0.0 1.4e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MatE PF01554.18 EWM23089.1 - 6.2e-20 71.5 4.4 9.6e-20 70.8 4.4 1.3 1 0 0 1 1 1 1 MatE Polysacc_synt_C PF14667.6 EWM23089.1 - 8.3e-05 22.7 1.5 8.3e-05 22.7 1.5 2.3 2 0 0 2 2 2 1 Polysaccharide biosynthesis C-terminal domain MurJ PF03023.14 EWM23089.1 - 0.0037 15.9 0.7 0.0049 15.5 0.7 1.2 1 0 0 1 1 1 1 Lipid II flippase MurJ TPR_6 PF13174.6 EWM23090.1 - 0.25 12.0 3.6 0.85 10.4 0.3 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EWM23090.1 - 2 8.8 4.7 0.63 10.3 1.5 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat IATP PF04568.12 EWM23090.1 - 7.9 7.0 6.0 0.87 10.1 0.6 2.0 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP WD40 PF00400.32 EWM23091.1 - 3.2e-12 46.8 0.2 0.0057 17.5 0.0 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM23091.1 - 4.3e-05 23.7 0.0 0.25 11.7 0.0 4.0 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 EWM23091.1 - 0.015 14.5 0.0 0.038 13.3 0.0 1.7 1 1 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Ge1_WD40 PF16529.5 EWM23091.1 - 0.086 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TMEM208_SND2 PF05620.11 EWM23092.1 - 2e-13 50.5 1.4 8.3e-13 48.5 1.4 1.8 1 1 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 ALG11_N PF15924.5 EWM23092.1 - 0.023 14.7 2.2 0.024 14.7 1.4 1.4 1 1 1 2 2 2 0 ALG11 mannosyltransferase N-terminus ABC_tran PF00005.27 EWM23093.1 - 6.8e-45 153.0 0.0 4.4e-31 108.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EWM23093.1 - 9.8e-42 143.5 9.0 1.3e-41 143.0 9.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EWM23093.1 - 4.5e-15 55.7 0.1 1.2e-06 28.2 0.0 2.9 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EWM23093.1 - 0.0029 17.9 2.0 0.29 11.4 0.7 3.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EWM23093.1 - 0.0043 17.5 2.9 0.025 15.0 0.8 2.9 3 1 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 EWM23093.1 - 0.0069 16.1 0.0 0.023 14.4 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.29 EWM23093.1 - 0.015 15.7 4.8 10 6.5 0.1 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 EWM23093.1 - 0.018 15.3 7.5 3.6 7.9 0.9 4.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 EWM23093.1 - 0.037 13.7 1.9 0.4 10.4 0.6 2.8 2 1 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 EWM23093.1 - 0.044 12.6 1.3 1.2 7.8 0.1 2.8 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_25 PF13481.6 EWM23093.1 - 0.044 13.3 1.4 3.3 7.2 0.1 3.2 3 0 0 3 3 3 0 AAA domain RICH PF05062.12 EWM23093.1 - 0.066 13.6 1.2 0.49 10.8 0.2 2.2 2 0 0 2 2 2 0 RICH domain ABC_tran PF00005.27 EWM23094.1 - 9.7e-16 58.5 0.0 1.1e-15 58.4 0.0 1.0 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 EWM23094.1 - 0.00062 19.4 0.0 0.00096 18.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EWM23094.1 - 0.0014 18.9 0.0 0.0017 18.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EWM23094.1 - 0.0028 18.0 0.0 0.0032 17.8 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 EWM23094.1 - 0.0034 16.7 0.0 0.0066 15.7 0.0 1.4 2 0 0 2 2 2 1 Zeta toxin RsgA_GTPase PF03193.16 EWM23094.1 - 0.006 16.5 0.0 0.0065 16.4 0.0 1.1 1 0 0 1 1 1 1 RsgA GTPase AAA_7 PF12775.7 EWM23094.1 - 0.011 15.3 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 EWM23094.1 - 0.012 15.8 0.0 0.015 15.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EWM23094.1 - 0.013 15.2 0.0 0.014 15.1 0.0 1.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 EWM23094.1 - 0.017 15.0 0.0 0.019 14.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EWM23094.1 - 0.031 13.9 0.0 0.039 13.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EWM23094.1 - 0.034 14.7 0.0 0.039 14.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EWM23094.1 - 0.037 14.0 0.0 0.041 13.8 0.0 1.1 1 0 0 1 1 1 0 Rad17 P-loop domain APS_kinase PF01583.20 EWM23094.1 - 0.088 12.7 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Adenylylsulphate kinase T2SSE PF00437.20 EWM23094.1 - 0.091 11.8 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 EWM23094.1 - 0.094 12.4 0.0 0.096 12.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EWM23094.1 - 0.21 11.3 0.0 0.27 10.9 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 EWM23094.1 - 0.21 12.0 0.0 0.3 11.5 0.0 1.3 1 0 0 1 1 1 0 RNA helicase LRR_6 PF13516.6 EWM23095.1 - 8.2e-13 47.3 14.0 0.0046 16.9 0.0 9.5 11 0 0 11 11 11 3 Leucine Rich repeat LRR_4 PF12799.7 EWM23095.1 - 3.8e-10 39.9 1.3 0.44 11.0 0.0 7.3 8 1 1 9 9 9 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EWM23095.1 - 1.1e-08 34.5 5.9 1.8 9.4 0.0 8.1 9 0 0 9 9 9 2 Leucine Rich Repeat LRR_8 PF13855.6 EWM23095.1 - 0.0002 21.1 6.0 26 4.7 0.1 7.8 8 1 0 8 8 8 1 Leucine rich repeat Trypsin_2 PF13365.6 EWM23097.1 - 2.1e-22 80.6 0.1 4.5e-22 79.6 0.1 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_3 PF17815.1 EWM23097.1 - 8.9e-22 77.5 0.0 1.5e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 PDZ domain Trypsin PF00089.26 EWM23097.1 - 3e-11 43.6 0.0 5.6e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 EWM23097.1 - 3.3e-06 27.3 0.0 3e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EWM23097.1 - 0.002 17.9 0.0 0.054 13.3 0.0 2.5 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EWM23097.1 - 0.002 18.4 0.0 0.0095 16.3 0.0 1.9 2 0 0 2 2 2 1 PDZ domain Peptidase_S46 PF10459.9 EWM23097.1 - 0.0056 15.4 0.2 0.048 12.3 0.0 2.2 3 0 0 3 3 3 1 Peptidase S46 Peptidase_S29 PF02907.15 EWM23097.1 - 0.082 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease ABC_membrane PF00664.23 EWM23098.1 - 4.8e-52 177.3 1.2 6e-52 177.0 1.2 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF2079 PF09852.9 EWM23098.1 - 0.29 9.9 4.1 0.54 9.1 4.1 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2079) adh_short PF00106.25 EWM23099.1 - 3.4e-38 131.1 0.0 6.2e-38 130.2 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EWM23099.1 - 1.2e-22 80.6 0.0 1.8e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM23099.1 - 7.3e-05 22.8 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EWM23099.1 - 0.0046 16.4 0.0 0.009 15.4 0.0 1.6 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) MFS_MOT1 PF16983.5 EWM23099.1 - 0.11 12.9 2.9 0.41 11.1 2.7 2.0 1 1 1 2 2 2 0 Molybdate transporter of MFS superfamily RabGAP-TBC PF00566.18 EWM23100.1 - 5.3e-25 88.3 0.0 1.9e-24 86.5 0.0 1.9 2 1 0 2 2 2 1 Rab-GTPase-TBC domain NYAP_N PF15439.6 EWM23100.1 - 0.6 9.3 6.9 1.7 7.8 0.0 2.2 2 0 0 2 2 2 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter GFO_IDH_MocA PF01408.22 EWM23104.1 - 2.1e-24 86.7 0.1 2.6e-24 86.4 0.1 1.1 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 EWM23104.1 - 0.0059 16.9 0.3 0.025 14.8 0.3 1.9 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 EWM23104.1 - 0.01 15.2 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 EWM23104.1 - 0.016 15.8 0.1 0.024 15.3 0.1 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 EWM23104.1 - 0.024 15.1 0.0 0.042 14.3 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_N PF00044.24 EWM23104.1 - 0.09 13.1 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain CoA_binding PF02629.19 EWM23104.1 - 0.12 13.1 1.7 0.14 12.9 0.3 1.8 2 1 0 2 2 2 0 CoA binding domain ThiF PF00899.21 EWM23104.1 - 0.14 11.4 0.1 0.22 10.9 0.1 1.2 1 0 0 1 1 1 0 ThiF family AAA_33 PF13671.6 EWM23105.1 - 0.0052 17.0 0.0 0.0068 16.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EWM23105.1 - 0.091 13.1 0.1 0.21 12.0 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 EWM23105.1 - 0.1 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.23 EWM23105.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 EWM23105.1 - 0.18 12.1 0.0 0.52 10.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain Sec16_C PF12931.7 EWM23106.1 - 2.7e-09 37.1 0.0 0.098 12.3 0.0 3.2 3 0 0 3 3 3 3 Sec23-binding domain of Sec16 SUIM_assoc PF16619.5 EWM23106.1 - 8.3e-07 29.0 10.8 0.0024 17.9 0.0 3.8 3 0 0 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 DUF3791 PF12668.7 EWM23106.1 - 0.29 11.2 0.0 0.48 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) NAD_binding_2 PF03446.15 EWM23107.1 - 2.1e-35 122.2 0.6 4.9e-35 121.0 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EWM23107.1 - 6.9e-25 87.7 2.0 9.8e-25 87.2 1.3 1.6 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 EWM23107.1 - 3.6e-06 27.5 0.0 1.2e-05 25.8 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EWM23107.1 - 1.2e-05 25.3 0.0 2.9e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 EWM23107.1 - 0.00017 21.0 0.0 0.00026 20.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 EWM23107.1 - 0.0042 17.3 0.0 0.009 16.3 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 EWM23107.1 - 0.013 15.7 0.0 0.041 14.1 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh PF00984.19 EWM23107.1 - 0.024 14.8 0.0 0.048 13.9 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain 3HCDH_N PF02737.18 EWM23107.1 - 0.096 12.6 0.0 0.33 10.8 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IF2_N PF04760.15 EWM23107.1 - 0.099 12.5 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region FAD_oxidored PF12831.7 EWM23108.1 - 1.3e-05 24.8 0.1 1.4e-05 24.6 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EWM23108.1 - 3.3e-05 22.8 0.2 4.3e-05 22.4 0.2 1.1 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 EWM23108.1 - 8e-05 21.9 0.2 0.00011 21.5 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EWM23108.1 - 0.00015 21.1 0.1 0.00019 20.7 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EWM23108.1 - 0.0015 18.7 0.0 0.0027 17.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EWM23108.1 - 0.071 12.2 0.1 0.091 11.8 0.1 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EWM23108.1 - 0.088 12.1 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EWM23109.1 - 1.9e-10 41.1 0.0 2.4e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EWM23109.1 - 1.1e-08 34.7 0.0 1.2e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EWM23109.1 - 0.005 16.2 0.0 0.0055 16.0 0.0 1.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 EWM23109.1 - 0.06 13.6 0.0 0.076 13.3 0.0 1.2 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 EWM23109.1 - 0.065 13.5 0.0 0.08 13.2 0.0 1.1 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 EWM23109.1 - 0.078 12.9 0.0 0.089 12.7 0.0 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Bac_transf PF02397.16 EWM23109.1 - 0.18 11.4 0.0 0.24 11.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial sugar transferase Pyr_redox_dim PF02852.22 EWM23110.1 - 2.2e-27 95.5 0.3 3.3e-27 94.9 0.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Lactamase_B PF00753.27 EWM23111.1 - 1.5e-10 41.4 0.1 1.9e-10 41.1 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 EWM23111.1 - 1.8e-08 34.1 0.0 2.4e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 EWM23111.1 - 3.2e-05 23.5 0.0 3.9e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EWM23111.1 - 0.00011 22.1 0.0 0.00016 21.6 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain AOX PF01786.17 EWM23112.1 - 0.12 12.0 0.0 4.1 6.9 0.0 2.3 1 1 0 1 1 1 0 Alternative oxidase Methyltr_RsmB-F PF01189.17 EWM23117.1 - 5.4e-20 71.9 0.0 8.1e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 EWM23117.1 - 0.00084 19.8 0.0 0.0017 18.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF CPSF73-100_C PF11718.8 EWM23119.1 - 6e-11 42.3 0.0 1e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term RMMBL PF07521.12 EWM23119.1 - 0.00052 19.9 0.0 0.00076 19.4 0.0 1.3 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain GOLD_2 PF13897.6 EWM23121.1 - 3.1e-08 34.2 5.1 0.0038 17.7 0.1 3.0 2 1 1 3 3 3 2 Golgi-dynamics membrane-trafficking DSPc PF00782.20 EWM23121.1 - 0.00013 21.8 0.0 0.00021 21.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain F-box PF00646.33 EWM23124.1 - 0.0011 18.8 0.7 0.0025 17.7 0.1 1.9 2 0 0 2 2 2 1 F-box domain Ribosomal_L24e PF01246.20 EWM23125.1 - 2.8e-31 107.5 5.1 7.1e-31 106.2 5.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e Helicase_PWI PF18149.1 EWM23125.1 - 0.024 14.8 0.4 0.047 13.9 0.4 1.4 1 0 0 1 1 1 0 N-terminal helicase PWI domain DUF2175 PF09943.9 EWM23125.1 - 5.6 7.3 6.1 0.8 10.0 0.7 2.2 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) adh_short PF00106.25 EWM23126.1 - 1.6e-38 132.2 0.0 1.9e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EWM23126.1 - 1.3e-22 80.5 0.0 1.6e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM23126.1 - 2.6e-11 43.8 0.1 3.5e-11 43.3 0.1 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EWM23126.1 - 0.00079 18.9 0.0 0.0013 18.1 0.0 1.5 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EWM23126.1 - 0.02 14.4 0.2 0.09 12.2 0.2 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DNA_pol_B PF00136.21 EWM23127.1 - 3.2e-144 481.1 0.0 4.3e-144 480.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EWM23127.1 - 3.4e-69 233.5 0.0 5.6e-69 232.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EWM23127.1 - 7.5e-17 61.6 4.6 1.4e-16 60.7 4.6 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 EWM23127.1 - 0.00061 18.8 0.0 0.0017 17.3 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.6 EWM23127.1 - 0.015 15.3 0.0 0.16 12.0 0.0 2.3 1 1 0 1 1 1 0 RNase_H superfamily C1_1 PF00130.22 EWM23127.1 - 0.32 10.9 4.6 1.1 9.2 4.6 1.9 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DNA_pol_B PF00136.21 EWM23128.1 - 3.7e-124 414.9 0.0 4.9e-124 414.5 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EWM23128.1 - 2.1e-69 234.3 0.0 3.4e-69 233.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_2 PF03175.13 EWM23128.1 - 0.00037 19.5 0.0 0.0012 17.8 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.6 EWM23128.1 - 0.0083 16.1 0.0 0.11 12.5 0.0 2.3 1 1 0 1 1 1 1 RNase_H superfamily TPM_phosphatase PF04536.14 EWM23129.1 - 2.5e-08 34.1 0.0 5.8e-08 32.9 0.0 1.6 2 0 0 2 2 2 1 TPM domain YrhK PF14145.6 EWM23129.1 - 0.17 11.8 0.3 2.3 8.2 0.0 2.5 2 1 0 2 2 2 0 YrhK-like protein Flagellin_IN PF07196.13 EWM23130.1 - 0.24 11.6 0.0 0.34 11.1 0.0 1.2 1 0 0 1 1 1 0 Flagellin hook IN motif S4 PF01479.25 EWM23131.1 - 1e-09 38.0 0.9 1e-09 38.0 0.9 2.4 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 EWM23131.1 - 3.3e-06 27.9 0.2 1.2e-05 26.1 0.0 2.0 1 1 1 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain PP2C PF00481.21 EWM23132.1 - 8.5e-11 42.0 0.0 0.00028 20.6 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C ATE_N PF04376.13 EWM23133.1 - 1.9e-29 101.9 3.9 3.8e-29 100.9 3.9 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus CCDC106 PF15794.5 EWM23133.1 - 0.028 14.1 3.5 0.04 13.6 3.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Pirin_C PF05726.13 EWM23134.1 - 1.9e-11 44.3 0.0 5e-11 42.9 0.0 1.7 1 1 0 1 1 1 1 Pirin C-terminal cupin domain Pirin PF02678.16 EWM23134.1 - 1.2e-05 25.2 0.0 2.6e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Pirin PEP-utilizers_C PF02896.18 EWM23135.1 - 1.8e-75 253.8 0.0 3e-75 253.0 0.0 1.3 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.19 EWM23135.1 - 7.4e-54 183.2 0.0 4e-39 134.8 0.0 3.3 1 1 1 2 2 2 2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 EWM23135.1 - 2.6e-25 87.9 3.2 2.6e-25 87.9 3.2 2.7 2 0 0 2 2 2 1 PEP-utilising enzyme, mobile domain Glyco_hydro_16 PF00722.21 EWM23136.1 - 3.6e-15 55.9 0.3 1.7e-14 53.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Sel1 PF08238.12 EWM23137.1 - 1.4e-21 76.4 46.4 2.8e-07 31.0 0.8 10.5 12 1 0 12 12 12 7 Sel1 repeat TPR_7 PF13176.6 EWM23137.1 - 0.038 14.0 13.9 2.1 8.6 0.2 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat SBP_bac_8 PF13416.6 EWM23137.1 - 0.11 12.3 2.2 0.35 10.6 2.2 1.9 1 1 0 1 1 1 0 Bacterial extracellular solute-binding protein TPR_1 PF00515.28 EWM23137.1 - 0.29 11.0 8.9 2.9 7.9 0.1 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.25 EWM23138.1 - 8.9e-61 205.6 0.0 1.1e-60 205.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM23138.1 - 4.1e-37 127.9 0.0 5.8e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EWM23138.1 - 2.5e-06 27.0 0.0 3.8e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EWM23138.1 - 0.0036 16.2 0.0 0.0054 15.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EWM23138.1 - 0.025 14.2 0.0 3.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Cellulase PF00150.18 EWM23139.1 - 8.9e-32 110.6 0.0 1.2e-31 110.2 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Sigma70_r2 PF04542.14 EWM23140.1 - 1.9e-19 69.2 0.2 3.7e-19 68.3 0.2 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 EWM23140.1 - 3.6e-19 68.0 1.0 1e-17 63.4 0.8 3.2 3 0 0 3 3 3 1 Sigma-70, region 4 Sigma70_r3 PF04539.16 EWM23140.1 - 1.3e-15 57.3 0.9 2.5e-11 43.5 0.0 3.2 3 0 0 3 3 3 2 Sigma-70 region 3 Sigma70_r4_2 PF08281.12 EWM23140.1 - 0.027 14.2 1.0 0.6 9.8 0.1 3.2 3 0 0 3 3 3 0 Sigma-70, region 4 AFG1_ATPase PF03969.16 EWM23141.1 - 1.3e-93 313.8 0.5 1.8e-64 217.9 0.1 2.1 1 1 1 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 EWM23141.1 - 0.011 16.1 0.1 0.22 11.9 0.0 2.4 1 1 1 2 2 2 0 AAA ATPase domain Bac_DnaA PF00308.18 EWM23141.1 - 0.027 14.3 0.1 0.21 11.4 0.0 2.3 2 1 0 2 2 2 0 Bacterial dnaA protein DUF2396 PF09654.10 EWM23141.1 - 0.13 12.4 0.5 0.5 10.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2396) Nup160 PF11715.8 EWM23142.1 - 0.0014 17.4 0.0 0.48 9.0 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Proteasome PF00227.26 EWM23143.1 - 1.1e-38 132.6 0.0 1.5e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit RAG2_PHD PF13341.6 EWM23143.1 - 0.16 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 RAG2 PHD domain Rad17 PF03215.15 EWM23144.1 - 6.5e-12 45.8 0.0 5e-11 42.9 0.0 2.1 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 EWM23144.1 - 0.00016 22.1 1.2 0.00078 19.9 1.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EWM23144.1 - 0.014 15.6 0.0 0.48 10.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EWM23144.1 - 0.023 14.4 0.1 0.046 13.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EWM23144.1 - 0.083 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 EWM23144.1 - 0.14 12.6 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 EWM23144.1 - 0.14 12.0 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase Mito_carr PF00153.27 EWM23145.1 - 4.2e-45 151.6 0.3 2.7e-18 65.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 EWM23145.1 - 0.067 13.6 0.3 0.71 10.3 0.0 2.5 3 0 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family Mito_carr PF00153.27 EWM23146.1 - 4.5e-45 151.5 0.4 2.6e-18 65.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 EWM23146.1 - 0.065 13.6 0.3 0.7 10.3 0.0 2.5 3 0 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family La PF05383.17 EWM23147.1 - 1e-13 51.1 0.0 2.1e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 La domain Lipase_3 PF01764.25 EWM23148.1 - 2.5e-06 27.4 0.0 6.6e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EWM23148.1 - 0.044 14.4 1.9 0.11 13.1 0.0 2.5 1 1 0 2 2 2 0 Alpha/beta hydrolase family UPF0227 PF05728.12 EWM23148.1 - 0.098 12.6 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF2838 PF10998.8 EWM23149.1 - 6.5e-37 126.2 7.9 6.5e-37 126.2 7.9 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Utp11 PF03998.13 EWM23150.1 - 0.0049 16.8 3.3 0.0069 16.3 3.3 1.2 1 0 0 1 1 1 1 Utp11 protein HMMR_N PF15905.5 EWM23150.1 - 0.03 13.8 6.5 0.048 13.1 6.5 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Surfac_D-trimer PF09006.11 EWM23150.1 - 0.094 12.6 0.2 0.6 10.0 0.1 2.2 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Spc29 PF17082.5 EWM23150.1 - 0.097 12.5 0.6 0.17 11.7 0.6 1.4 1 0 0 1 1 1 0 Spindle Pole Component 29 Trefoil PF00088.18 EWM23150.1 - 0.18 11.7 1.9 0.45 10.5 1.9 1.6 1 0 0 1 1 1 0 Trefoil (P-type) domain SlyX PF04102.12 EWM23150.1 - 2.3 8.9 7.1 0.94 10.1 1.2 3.2 1 1 2 3 3 3 0 SlyX Fez1 PF06818.15 EWM23150.1 - 2.8 8.4 9.7 5.5 7.4 9.0 1.8 1 1 0 1 1 1 0 Fez1 PRKG1_interact PF15898.5 EWM23150.1 - 9.9 7.1 10.6 3.4 8.6 5.7 2.3 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain SOR_SNZ PF01680.17 EWM23151.1 - 3.2e-110 366.8 9.8 3.2e-110 366.8 9.8 1.4 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.14 EWM23151.1 - 1.6e-07 30.9 6.8 2e-06 27.3 0.1 2.6 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG TetR_C_27 PF17935.1 EWM23151.1 - 0.00019 21.5 0.0 0.00068 19.7 0.0 1.9 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain His_biosynth PF00977.21 EWM23151.1 - 0.00074 19.0 0.6 0.054 13.0 0.0 2.4 2 1 0 2 2 2 1 Histidine biosynthesis protein Dus PF01207.17 EWM23151.1 - 0.0016 17.6 0.3 1.5 7.8 0.0 2.5 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) IGPS PF00218.21 EWM23151.1 - 0.014 14.6 0.1 0.22 10.7 0.0 2.3 2 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase Fapy_DNA_glyco PF01149.24 EWM23151.1 - 0.029 15.0 0.1 0.16 12.6 0.0 2.0 2 0 0 2 2 2 0 Formamidopyrimidine-DNA glycosylase N-terminal domain NanE PF04131.14 EWM23151.1 - 0.039 13.1 2.0 0.15 11.3 0.0 2.5 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase SOR_SNZ PF01680.17 EWM23152.1 - 2.8e-90 301.7 3.9 2.8e-90 301.7 3.9 1.5 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.14 EWM23152.1 - 2.3e-07 30.4 3.0 1.4e-06 27.8 0.1 2.6 2 1 0 3 3 3 1 Thiazole biosynthesis protein ThiG TetR_C_27 PF17935.1 EWM23152.1 - 0.00013 22.0 0.0 0.00051 20.1 0.0 2.0 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain His_biosynth PF00977.21 EWM23152.1 - 0.0009 18.8 0.1 0.038 13.4 0.0 2.4 2 1 0 2 2 2 1 Histidine biosynthesis protein Dus PF01207.17 EWM23152.1 - 0.0015 17.7 0.2 1.3 8.0 0.0 2.4 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.14 EWM23152.1 - 0.0099 15.1 0.3 0.11 11.7 0.0 2.4 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.15 EWM23152.1 - 0.029 13.8 1.8 0.09 12.1 0.2 2.1 2 0 0 2 2 2 0 Nitronate monooxygenase IMPDH PF00478.25 EWM23152.1 - 0.051 12.6 0.4 0.071 12.1 0.4 1.3 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain IGPS PF00218.21 EWM23152.1 - 0.066 12.4 0.0 0.16 11.1 0.0 1.6 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase TMP-TENI PF02581.17 EWM23152.1 - 0.071 12.4 1.1 1.1 8.5 0.1 2.9 3 0 0 3 3 3 0 Thiamine monophosphate synthase COesterase PF00135.28 EWM23154.1 - 2.3e-98 330.3 0.0 2.9e-98 330.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EWM23154.1 - 4.8e-09 36.4 0.3 1.3e-08 35.0 0.3 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EWM23154.1 - 0.00033 20.2 0.3 0.00073 19.1 0.3 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EWM23154.1 - 0.0078 16.8 0.2 0.018 15.7 0.1 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family GCV_T PF01571.21 EWM23155.1 - 1.4e-11 44.2 0.0 1.1e-10 41.3 0.0 2.0 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain DUF1631 PF07793.11 EWM23156.1 - 0.51 8.7 1.6 0.58 8.5 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) DUF1631 PF07793.11 EWM23157.1 - 0.54 8.6 1.6 0.62 8.4 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) DUF1664 PF07889.12 EWM23158.1 - 0.0016 18.5 12.3 3.5 7.7 3.8 4.0 3 1 2 5 5 5 3 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 EWM23158.1 - 0.004 17.6 1.7 3.8 8.1 0.3 3.1 2 1 1 3 3 3 2 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 EWM23158.1 - 0.02 15.0 2.0 0.93 9.5 0.7 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus BshC PF10079.9 EWM23158.1 - 0.064 12.0 14.2 0.067 11.9 5.2 3.0 2 1 0 3 3 3 0 Bacillithiol biosynthesis BshC SKA2 PF16740.5 EWM23158.1 - 0.082 12.7 0.2 0.082 12.7 0.2 4.3 2 2 2 4 4 4 0 Spindle and kinetochore-associated protein 2 Mer2 PF09074.10 EWM23158.1 - 0.12 12.2 8.8 0.035 13.9 4.8 2.0 2 1 0 2 2 2 0 Mer2 Nup54 PF13874.6 EWM23158.1 - 0.72 10.0 32.5 0.4 10.8 9.8 4.1 3 2 1 4 4 4 0 Nucleoporin complex subunit 54 CCDC154 PF15450.6 EWM23158.1 - 3.4 6.1 30.0 0.051 12.1 18.2 2.6 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 154 MRP-S31 PF15433.6 EWM23158.1 - 3.4 7.2 9.2 25 4.4 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 SesA PF17107.5 EWM23158.1 - 5 7.3 8.7 13 5.9 0.5 3.3 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases FlaC_arch PF05377.11 EWM23158.1 - 6.2 7.3 14.3 23 5.5 0.2 5.0 5 1 0 5 5 5 0 Flagella accessory protein C (FlaC) Aldo_ket_red PF00248.21 EWM23159.1 - 4.3e-34 118.1 0.0 5.3e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF4995 PF16386.5 EWM23159.1 - 0.089 12.8 0.0 7 6.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function RRM_1 PF00076.22 EWM23160.1 - 2.6e-11 43.2 0.0 6.9e-09 35.4 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) p450 PF00067.22 EWM23162.1 - 1.5e-56 192.1 0.0 2.2e-56 191.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_16 PF10294.9 EWM23163.1 - 4.5e-23 81.9 0.0 6.6e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Ank_4 PF13637.6 EWM23163.1 - 4.5e-17 62.2 1.7 3.9e-13 49.6 0.3 3.0 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EWM23163.1 - 1.4e-15 57.6 0.1 1e-14 54.8 0.1 2.3 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EWM23163.1 - 3.1e-13 48.6 0.0 0.00015 21.9 0.0 4.0 4 0 0 4 4 3 2 Ankyrin repeat Ank PF00023.30 EWM23163.1 - 1.2e-12 47.7 0.4 0.00011 22.4 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EWM23163.1 - 6.4e-12 45.5 1.9 3.6e-05 23.9 0.1 3.5 3 1 1 4 4 3 2 Ankyrin repeats (many copies) MTS PF05175.14 EWM23163.1 - 0.0003 20.4 0.2 0.0016 18.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EWM23163.1 - 0.0039 17.9 0.0 0.0096 16.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM23163.1 - 0.018 14.9 0.0 0.044 13.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EWM23163.1 - 0.022 15.5 0.0 0.045 14.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EWM23163.1 - 0.067 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Rtt106 PF08512.12 EWM23164.1 - 1.3e-22 80.0 0.0 5.2e-21 74.9 0.0 2.8 3 0 0 3 3 3 1 Histone chaperone Rttp106-like HMG_box PF00505.19 EWM23164.1 - 7.1e-22 77.6 0.6 7.1e-22 77.6 0.6 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box SSrecog PF03531.14 EWM23164.1 - 7.1e-22 77.1 0.2 3.5e-21 74.9 0.0 2.2 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) HMG_box_2 PF09011.10 EWM23164.1 - 6.7e-15 55.4 1.2 6.7e-15 55.4 1.2 2.0 2 0 0 2 2 2 1 HMG-box domain POB3_N PF17292.2 EWM23164.1 - 1.1e-14 54.7 0.1 7.5e-13 48.7 0.1 2.6 2 0 0 2 2 2 1 POB3-like N-terminal PH domain CHDNT PF08073.12 EWM23164.1 - 0.011 15.7 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 CHDNT (NUC034) domain SDA1 PF05285.12 EWM23164.1 - 0.075 12.4 34.6 0.12 11.7 34.6 1.3 1 0 0 1 1 1 0 SDA1 Apt1 PF10351.9 EWM23164.1 - 1.8 7.4 12.5 2.9 6.7 12.5 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain YbaB_DNA_bd PF02575.16 EWM23166.1 - 6.1e-07 29.6 0.1 1.5e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family Gemini_AC4_5 PF04807.12 EWM23166.1 - 0.24 11.1 0.2 0.45 10.2 0.2 1.5 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region Complex1_LYR PF05347.15 EWM23167.1 - 8.2e-07 29.0 0.3 1.6e-06 28.1 0.1 1.5 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EWM23167.1 - 0.12 13.2 0.0 0.15 12.8 0.0 1.2 1 0 0 1 1 1 0 Complex1_LYR-like CD36 PF01130.21 EWM23168.1 - 4.2e-51 173.9 0.0 1.9e-30 105.9 0.0 2.1 2 0 0 2 2 2 2 CD36 family Aldo_ket_red PF00248.21 EWM23169.1 - 1.5e-35 122.8 0.0 2.2e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DnaJ PF00226.31 EWM23169.1 - 0.085 13.0 0.1 0.37 11.0 0.1 1.9 2 0 0 2 2 2 0 DnaJ domain CRAL_TRIO PF00650.20 EWM23172.1 - 2.6e-22 79.3 0.0 3.5e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EWM23172.1 - 5.1e-07 29.9 0.0 7.4e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain ATG16 PF08614.11 EWM23173.1 - 0.00081 19.7 26.1 0.00081 19.7 26.1 1.6 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 EWM23173.1 - 0.56 9.5 17.4 0.69 9.2 17.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 EWM23173.1 - 1.4 8.4 16.7 2 7.9 16.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Lzipper-MIP1 PF14389.6 EWM23173.1 - 4.6 7.6 22.4 0.98 9.8 2.4 3.6 3 1 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Fmp27_WPPW PF10359.9 EWM23173.1 - 5.1 5.8 19.2 0.83 8.4 4.8 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF2052 PF09747.9 EWM23173.1 - 5.3 7.1 13.4 8.6 6.4 13.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Halogen_Hydrol PF10112.9 EWM23173.1 - 8.2 6.4 12.5 4.4 7.3 0.2 2.6 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein YbaB_DNA_bd PF02575.16 EWM23174.1 - 1.1e-10 41.6 2.1 1.7e-10 40.9 2.1 1.3 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family PP2C PF00481.21 EWM23175.1 - 1.2e-56 192.3 0.0 1.8e-56 191.7 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Exo_endo_phos PF03372.23 EWM23176.1 - 6.6e-17 61.8 0.1 1.1e-16 61.1 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SRP-alpha_N PF04086.13 EWM23176.1 - 6.4 6.6 10.1 10 5.9 10.1 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Lactonase PF10282.9 EWM23177.1 - 2.1e-13 50.3 0.0 5.6e-06 25.8 0.0 4.1 1 1 3 4 4 4 4 Lactonase, 7-bladed beta-propeller WD40 PF00400.32 EWM23177.1 - 0.031 15.2 0.1 0.59 11.1 0.0 3.1 4 0 0 4 4 4 0 WD domain, G-beta repeat SGL PF08450.12 EWM23177.1 - 0.089 12.4 0.0 48 3.4 0.0 3.6 2 1 1 4 4 4 0 SMP-30/Gluconolactonase/LRE-like region YgbB PF02542.16 EWM23179.1 - 2e-60 203.5 0.0 2.6e-60 203.2 0.0 1.1 1 0 0 1 1 1 1 YgbB family F1F0-ATPsyn_F PF10791.9 EWM23180.1 - 0.0048 17.3 0.3 0.0061 17.0 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi PAP_central PF04928.17 EWM23181.1 - 7.9e-65 218.3 0.0 1.1e-64 217.8 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain NTP_transf_2 PF01909.23 EWM23181.1 - 0.0002 21.6 0.0 0.00037 20.7 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Metallophos_2 PF12850.7 EWM23182.1 - 5.7e-18 65.6 0.1 7.2e-18 65.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EWM23182.1 - 4.1e-05 24.2 0.1 0.019 15.5 0.1 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PPR_2 PF13041.6 EWM23184.1 - 1.4e-48 162.8 0.0 6.2e-14 51.9 0.0 8.5 7 2 2 9 9 9 6 PPR repeat family PPR PF01535.20 EWM23184.1 - 1.1e-34 116.2 15.9 2.2e-05 24.4 0.0 11.9 13 1 0 13 13 12 8 PPR repeat PPR_3 PF13812.6 EWM23184.1 - 1.4e-33 114.8 0.0 4.8e-10 39.4 0.0 7.4 3 2 5 8 8 8 7 Pentatricopeptide repeat domain PPR_1 PF12854.7 EWM23184.1 - 1.4e-30 104.7 0.5 0.00011 21.8 0.0 10.0 10 1 0 10 10 10 5 PPR repeat PPR_long PF17177.4 EWM23184.1 - 6.6e-17 61.6 0.0 2.4e-05 23.8 0.0 5.3 2 1 3 5 5 5 3 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 EWM23184.1 - 0.0003 21.4 23.5 0.92 10.5 0.0 7.8 8 1 1 9 9 7 2 Tetratricopeptide repeat BTAD PF03704.17 EWM23184.1 - 0.00058 20.3 1.5 4.7 7.6 0.1 3.9 3 0 0 3 3 3 1 Bacterial transcriptional activator domain HrpB1_HrpK PF09613.10 EWM23184.1 - 0.0041 16.8 1.4 2.1 8.0 0.1 3.5 2 1 1 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_19 PF14559.6 EWM23184.1 - 0.0055 17.2 6.1 0.84 10.2 0.2 4.6 5 1 1 6 6 4 2 Tetratricopeptide repeat COX5A PF02284.16 EWM23184.1 - 0.035 14.1 0.0 8.6 6.4 0.0 3.2 2 1 1 3 3 3 0 Cytochrome c oxidase subunit Va Lambda_tail_I PF06805.12 EWM23184.1 - 0.098 13.0 0.2 15 6.1 0.0 4.0 3 1 1 4 4 4 0 Bacteriophage lambda tail assembly protein I Clathrin PF00637.20 EWM23184.1 - 0.11 12.4 0.0 2.2 8.1 0.0 2.9 3 0 0 3 3 3 0 Region in Clathrin and VPS TPR_6 PF13174.6 EWM23184.1 - 0.39 11.4 2.2 32 5.4 0.2 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat Lipase_GDSL PF00657.22 EWM23185.1 - 5.2e-10 39.6 0.0 7.1e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 EWM23185.1 - 0.00011 22.7 0.1 0.00018 21.9 0.1 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Patatin PF01734.22 EWM23186.1 - 9.7e-11 42.2 4.3 5.6e-10 39.7 3.3 2.1 2 0 0 2 2 2 1 Patatin-like phospholipase DAGAT PF03982.13 EWM23187.1 - 5.6e-44 150.2 0.0 7.3e-44 149.9 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase TAFH PF07531.14 EWM23188.1 - 0.17 12.0 1.5 0.38 10.9 0.2 2.0 1 1 1 2 2 2 0 NHR1 homology to TAF TAFH PF07531.14 EWM23189.1 - 0.36 11.0 0.1 0.36 11.0 0.1 2.6 2 1 1 3 3 3 0 NHR1 homology to TAF PPIP5K2_N PF18086.1 EWM23190.1 - 5.8e-37 125.7 0.0 8e-37 125.3 0.0 1.2 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain Synaptobrevin PF00957.21 EWM23191.1 - 5.1e-13 48.6 0.1 9.4e-13 47.8 0.1 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EWM23191.1 - 6.8e-11 42.1 0.0 1.4e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain KH_1 PF00013.29 EWM23192.1 - 0.00026 20.8 0.2 0.00053 19.7 0.2 1.5 1 0 0 1 1 1 1 KH domain KH_8 PF17903.1 EWM23192.1 - 0.063 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Krr1 KH1 domain Steroid_dh PF02544.16 EWM23193.1 - 6.7e-22 78.1 0.1 1.1e-21 77.5 0.1 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 EWM23193.1 - 0.0026 17.3 0.1 0.0041 16.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 EWM23193.1 - 0.0063 16.9 0.2 0.013 15.9 0.2 1.5 1 0 0 1 1 1 1 Phospholipid methyltransferase FGGY_N PF00370.21 EWM23194.1 - 1.7e-06 27.8 0.0 0.0012 18.5 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Acyl_transf_1 PF00698.21 EWM23195.1 - 0.08 12.4 0.3 0.11 12.0 0.3 1.1 1 0 0 1 1 1 0 Acyl transferase domain UBM PF14377.6 EWM23197.1 - 0.68 9.5 2.5 1.4 8.4 2.5 1.5 1 0 0 1 1 1 0 Ubiquitin binding region Ras PF00071.22 EWM23199.1 - 2.4e-38 131.3 0.0 3.1e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EWM23199.1 - 3.4e-28 98.3 0.0 4.4e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EWM23199.1 - 1e-08 34.9 0.0 1.3e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EWM23199.1 - 0.00036 20.6 0.0 0.00047 20.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EWM23199.1 - 0.016 14.6 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EWM23199.1 - 0.02 14.8 0.0 0.047 13.6 0.0 1.6 1 1 1 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 EWM23199.1 - 0.14 12.5 0.0 0.21 11.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 EWM23199.1 - 0.2 11.2 0.0 0.61 9.6 0.0 1.7 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain NAD_binding_1 PF00175.21 EWM23202.1 - 1.4e-14 54.6 0.0 2.1e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EWM23202.1 - 6e-14 52.2 0.0 9.2e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EWM23202.1 - 0.00016 21.8 0.0 0.00026 21.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Zn_clus PF00172.18 EWM23204.1 - 3.6e-09 36.6 7.1 6.4e-09 35.8 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 EWM23205.1 - 3.4e-06 27.1 14.3 7.9e-06 25.9 14.3 1.7 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Viral_Beta_CD PF04530.12 EWM23206.1 - 0.092 13.0 0.1 0.14 12.5 0.1 1.3 1 0 0 1 1 1 0 Viral Beta C/D like family LEA_5 PF00477.17 EWM23207.1 - 0.25 11.8 13.7 0.3 11.6 13.7 1.1 1 0 0 1 1 1 0 Small hydrophilic plant seed protein Chloroa_b-bind PF00504.21 EWM23208.1 - 6.4e-16 59.3 0.0 7.8e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein EXS PF03124.14 EWM23211.1 - 1.6e-08 34.3 0.6 1.6e-08 34.2 0.6 1.0 1 0 0 1 1 1 1 EXS family FA_desaturase PF00487.24 EWM23212.1 - 1e-08 35.3 0.1 1.4e-08 34.9 0.1 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Diphthami_syn_2 PF01902.17 EWM23218.1 - 9e-10 38.4 0.2 6.3e-05 22.6 0.1 2.1 2 0 0 2 2 2 2 Diphthamide synthase ABC1 PF03109.16 EWM23221.1 - 3.1e-06 27.4 0.1 3.4e-06 27.2 0.1 1.1 1 0 0 1 1 1 1 ABC1 family Beta-lactamase PF00144.24 EWM23222.1 - 6.2e-13 48.7 0.1 7.2e-13 48.5 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF1611 PF07755.11 EWM23223.1 - 0.081 12.2 0.0 0.12 11.7 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1611_C) P-loop domain PRP38_assoc PF12871.7 EWM23225.1 - 0.02 15.5 1.0 0.024 15.2 1.0 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term XG_FTase PF03254.13 EWM23227.1 - 0.031 12.9 0.0 0.17 10.5 0.0 2.1 3 0 0 3 3 3 0 Xyloglucan fucosyltransferase Glyco_transf_11 PF01531.16 EWM23227.1 - 0.074 12.3 0.1 3.4 6.8 0.0 2.2 1 1 1 2 2 2 0 Glycosyl transferase family 11 Peptidase_S8 PF00082.22 EWM23228.1 - 3.5e-27 95.4 4.0 5.5e-27 94.8 4.0 1.3 1 0 0 1 1 1 1 Subtilase family HAP2-GCS1 PF10699.9 EWM23229.1 - 0.06 13.3 1.8 12 6.0 0.0 3.3 2 1 1 3 3 3 0 Male gamete fusion factor HEAT PF02985.22 EWM23231.1 - 8.5e-07 28.7 4.7 1.5 9.2 0.1 5.4 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 EWM23231.1 - 7.3e-06 26.3 3.6 0.056 13.8 0.0 4.8 4 1 0 4 4 4 2 HEAT repeats DUF2532 PF10811.8 EWM23231.1 - 0.11 12.5 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2532) Cnd1 PF12717.7 EWM23231.1 - 0.15 12.1 0.0 9.8 6.2 0.0 2.6 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 AC_N PF16214.5 EWM23231.1 - 0.32 10.1 1.2 0.53 9.4 1.2 1.4 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region HEAT_EZ PF13513.6 EWM23231.1 - 0.5 10.9 13.1 1.9 9.1 0.1 5.2 6 0 0 6 6 6 0 HEAT-like repeat Chloroa_b-bind PF00504.21 EWM23233.1 - 1.3e-18 68.1 0.0 1.9e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Fasciclin PF02469.22 EWM23234.1 - 1.8e-37 128.4 0.2 2.3e-37 128.1 0.2 1.1 1 0 0 1 1 1 1 Fasciclin domain SHMT PF00464.19 EWM23234.1 - 0.051 12.2 0.3 0.07 11.7 0.3 1.1 1 0 0 1 1 1 0 Serine hydroxymethyltransferase HrcA_DNA-bdg PF03444.15 EWM23234.1 - 0.058 13.0 0.0 0.16 11.6 0.0 1.7 2 0 0 2 2 2 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding NUC202 PF08166.12 EWM23234.1 - 0.088 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 NUC202 domain Sec66 PF09802.9 EWM23235.1 - 0.23 11.1 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 Glyco_transf_92 PF01697.27 EWM23238.1 - 6e-13 49.1 0.0 8.6e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 EWM23238.1 - 0.019 15.4 0.0 0.073 13.6 0.0 2.0 1 1 0 1 1 1 0 Glycosyl transferase family 2 Pyrophosphatase PF00719.19 EWM23239.1 - 5e-31 107.7 0.0 6.5e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase adh_short_C2 PF13561.6 EWM23240.1 - 0.031 13.8 0.0 0.058 12.9 0.0 1.4 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase SR-25 PF10500.9 EWM23240.1 - 0.47 10.0 2.9 0.55 9.8 2.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein adh_short PF00106.25 EWM23241.1 - 3.6e-12 46.2 0.7 8.9e-09 35.1 0.7 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EWM23241.1 - 1.3e-07 31.5 0.6 0.0096 15.5 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.19 EWM23241.1 - 0.021 14.1 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF5562 PF17717.1 EWM23241.1 - 0.091 12.7 0.2 0.17 11.8 0.2 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5562) Methyltransf_22 PF13383.6 EWM23245.1 - 3.2e-69 233.3 0.1 4.2e-69 232.9 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 EWM23245.1 - 6.5e-06 26.3 0.0 1.1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_22 PF13383.6 EWM23246.1 - 3.7e-69 233.1 0.2 4.8e-69 232.7 0.2 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 EWM23246.1 - 5.9e-06 26.4 0.0 9.3e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain HhH-GPD PF00730.25 EWM23247.1 - 6.6e-13 49.1 0.0 9.7e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Vac14_Fab1_bd PF12755.7 EWM23248.1 - 0.025 15.2 0.5 0.044 14.4 0.1 1.6 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region bZIP_2 PF07716.15 EWM23248.1 - 0.042 13.9 0.7 0.063 13.4 0.7 1.3 1 0 0 1 1 1 0 Basic region leucine zipper DUF3995 PF13160.6 EWM23254.1 - 0.047 14.0 0.2 0.067 13.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3995) CCDC53 PF10152.9 EWM23257.1 - 3.5 8.0 5.9 27 5.1 5.9 2.0 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex FAM176 PF14851.6 EWM23259.1 - 0.054 13.2 5.2 0.06 13.0 5.2 1.1 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 EWM23259.1 - 0.19 11.1 5.6 0.2 10.9 5.6 1.1 1 0 0 1 1 1 0 NOA36 protein Pox_Ag35 PF03286.14 EWM23259.1 - 1 9.1 6.4 1 9.1 6.4 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Adeno_terminal PF02459.15 EWM23259.1 - 1.8 6.8 7.6 1.9 6.8 7.6 1.0 1 0 0 1 1 1 0 Adenoviral DNA terminal protein DUF4746 PF15928.5 EWM23259.1 - 2 7.8 8.8 1.9 7.8 8.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Nop14 PF04147.12 EWM23259.1 - 2.3 6.3 10.7 2.3 6.3 10.7 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EWM23259.1 - 2.7 6.2 8.1 2.7 6.2 8.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Smr PF01713.21 EWM23260.1 - 0.044 14.1 0.1 0.26 11.7 0.0 2.3 2 1 0 2 2 2 0 Smr domain ABC_tran PF00005.27 EWM23265.1 - 2e-08 34.8 0.1 3.1e-08 34.2 0.1 1.2 1 0 0 1 1 1 1 ABC transporter Rad17 PF03215.15 EWM23265.1 - 0.00091 19.2 0.2 0.0014 18.6 0.2 1.3 1 1 0 1 1 1 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 EWM23265.1 - 0.0065 16.4 0.0 0.0096 15.8 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EWM23265.1 - 0.0085 16.5 0.1 0.015 15.7 0.1 1.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EWM23265.1 - 0.018 15.3 0.0 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EWM23265.1 - 0.018 15.5 0.0 0.03 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EWM23265.1 - 0.026 14.8 0.1 0.037 14.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_35 PF14516.6 EWM23265.1 - 0.039 12.8 0.0 0.047 12.5 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain AAA_25 PF13481.6 EWM23265.1 - 0.086 12.4 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 EWM23265.1 - 0.094 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 EWM23265.1 - 0.12 13.0 0.3 0.24 12.0 0.3 1.5 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 EWM23265.1 - 0.14 11.8 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain PRK PF00485.18 EWM23265.1 - 0.15 11.8 0.2 0.42 10.3 0.1 1.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.6 EWM23265.1 - 0.16 11.7 0.1 0.3 10.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 EWM23265.1 - 0.16 12.4 0.0 0.33 11.4 0.0 1.5 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EWM23265.1 - 0.21 11.3 0.0 0.32 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EWM23265.1 - 0.24 11.1 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase_2 PF01637.18 EWM23265.1 - 0.25 11.2 0.0 0.31 10.9 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Isy1 PF06246.12 EWM23267.1 - 1.7e-90 303.0 9.1 2.2e-90 302.7 9.1 1.1 1 0 0 1 1 1 1 Isy1-like splicing family DivIVA PF05103.13 EWM23267.1 - 0.079 13.0 6.8 1.3 9.1 2.7 2.4 2 0 0 2 2 2 0 DivIVA protein DUF737 PF05300.11 EWM23267.1 - 5.4 7.3 11.6 1.2 9.5 4.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF737) PUF PF00806.19 EWM23275.1 - 3.4e-35 117.7 1.8 3.4e-09 35.9 0.0 4.3 4 0 0 4 4 4 4 Pumilio-family RNA binding repeat CPL PF08144.11 EWM23275.1 - 0.00038 20.8 0.0 0.84 10.0 0.0 3.5 1 1 2 3 3 3 2 CPL (NUC119) domain PriX PF18689.1 EWM23275.1 - 0.077 13.4 0.5 0.25 11.7 0.2 1.9 1 1 1 2 2 2 0 Primase X sCache_2 PF17200.4 EWM23275.1 - 0.088 12.7 0.0 10 5.9 0.0 2.2 2 0 0 2 2 2 0 Single Cache domain 2 DUF2052 PF09747.9 EWM23277.1 - 0.0015 18.7 7.3 0.0023 18.1 7.3 1.3 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) HAD PF12710.7 EWM23277.1 - 0.0031 17.9 1.3 1.1 9.6 0.0 3.1 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase TMEM51 PF15345.6 EWM23277.1 - 0.18 11.6 1.2 0.28 11.0 1.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 CENP-B_dimeris PF09026.10 EWM23277.1 - 0.22 11.9 7.6 0.48 10.8 7.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Radial_spoke PF04712.12 EWM23277.1 - 0.29 10.0 10.7 0.38 9.6 10.7 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein RPN2_C PF18004.1 EWM23277.1 - 0.3 11.0 9.0 0.5 10.3 9.0 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4746 PF15928.5 EWM23277.1 - 0.49 9.8 12.4 0.7 9.3 12.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4820 PF16091.5 EWM23277.1 - 0.73 9.1 2.9 1.1 8.5 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Eapp_C PF10238.9 EWM23277.1 - 0.82 9.7 4.3 1.5 8.9 4.3 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein FAM176 PF14851.6 EWM23277.1 - 1 9.0 10.3 2.5 7.8 10.3 1.6 1 0 0 1 1 1 0 FAM176 family RXT2_N PF08595.11 EWM23277.1 - 1.1 9.3 8.4 1.8 8.5 8.4 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal RNA_pol_Rpc4 PF05132.14 EWM23277.1 - 1.1 9.7 4.1 2.3 8.7 4.1 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Nop14 PF04147.12 EWM23277.1 - 1.1 7.4 12.6 1.4 7.0 12.6 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2201_N PF13203.6 EWM23277.1 - 1.2 8.6 4.5 2.1 7.9 4.5 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Pox_Ag35 PF03286.14 EWM23277.1 - 1.3 8.7 9.9 2.1 8.1 9.9 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein EIIBC-GUT_N PF03612.14 EWM23277.1 - 1.5 8.5 3.1 2.4 7.9 3.1 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Nucleo_P87 PF07267.11 EWM23277.1 - 1.6 7.5 6.4 2.2 7.1 6.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Ribosomal_60s PF00428.19 EWM23277.1 - 1.7 9.3 14.8 5.3 7.7 14.8 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein DASH_Spc19 PF08287.11 EWM23277.1 - 2.3 8.1 9.5 4 7.3 9.5 1.3 1 0 0 1 1 1 0 Spc19 CENP-N PF05238.13 EWM23277.1 - 2.7 7.2 5.3 5.2 6.3 5.3 1.4 1 0 0 1 1 1 0 Kinetochore protein CHL4 like ORC_WH_C PF18137.1 EWM23277.1 - 2.9 8.0 9.2 5.8 7.0 9.2 1.4 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Vfa1 PF08432.10 EWM23277.1 - 3.5 7.9 11.5 5.7 7.2 11.5 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Myc_N PF01056.18 EWM23277.1 - 4.2 7.2 10.1 6.9 6.5 10.1 1.3 1 0 0 1 1 1 0 Myc amino-terminal region FGF-BP1 PF06473.12 EWM23277.1 - 4.3 7.1 8.6 8.5 6.1 8.6 1.4 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) NOA36 PF06524.12 EWM23277.1 - 4.9 6.4 11.4 7.5 5.8 11.4 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 EWM23277.1 - 7.6 4.5 12.8 11 4.0 12.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Afi1 PF07792.12 EWM23277.1 - 9.6 6.7 8.9 17 5.9 8.9 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Ank_5 PF13857.6 EWM23278.1 - 8.9e-10 38.6 0.2 0.0076 16.5 0.1 3.7 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EWM23278.1 - 7.8e-06 25.9 0.0 5.1 8.0 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 EWM23278.1 - 1.1e-05 25.9 0.0 0.013 16.1 0.0 2.4 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EWM23278.1 - 0.001 19.4 0.2 25 5.5 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 EWM23278.1 - 0.014 16.0 0.0 0.35 11.5 0.0 2.7 1 1 2 3 3 3 0 Ankyrin repeats (many copies) Beach PF02138.18 EWM23279.1 - 6.7e-116 386.5 0.0 9.5e-116 386.0 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 EWM23279.1 - 3.6e-11 43.0 0.0 6.7e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH FUN14 PF04930.15 EWM23280.1 - 1.2e-19 70.5 1.1 1.7e-19 70.0 1.1 1.2 1 0 0 1 1 1 1 FUN14 family SLX9 PF15341.6 EWM23281.1 - 1.8e-06 28.4 4.0 4.5e-06 27.1 4.0 1.7 1 1 0 1 1 1 1 Ribosome biogenesis protein SLX9 RPA_C PF08784.11 EWM23281.1 - 0.12 13.0 1.0 0.19 12.4 1.0 1.4 1 0 0 1 1 1 0 Replication protein A C terminal Aminotran_4 PF01063.19 EWM23282.1 - 1e-31 110.5 0.0 1.5e-31 110.0 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Thioredoxin_8 PF13905.6 EWM23283.1 - 3.6e-24 84.9 0.0 6e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like fn3 PF00041.21 EWM23283.1 - 5.3e-08 33.1 0.0 0.00031 21.0 0.0 2.9 2 1 0 2 2 2 2 Fibronectin type III domain Thioredoxin PF00085.20 EWM23283.1 - 2.1e-05 24.4 0.0 0.00035 20.5 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 EWM23283.1 - 0.0011 19.4 0.0 0.0029 18.0 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin-like domain Pur_ac_phosph_N PF16656.5 EWM23283.1 - 0.0039 17.7 0.0 1.2 9.7 0.0 2.4 2 0 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain AhpC-TSA PF00578.21 EWM23283.1 - 0.0088 16.0 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Dymeclin PF09742.9 EWM23284.1 - 3.8e-45 154.4 0.0 5.1e-45 154.1 0.0 1.1 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Ribosomal_S7e PF01251.18 EWM23287.1 - 1.2e-81 272.9 2.3 1.4e-81 272.7 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e DHBP_synthase PF00926.19 EWM23288.1 - 1.6e-84 282.3 0.2 2.6e-84 281.5 0.2 1.4 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase GTP_cyclohydro2 PF00925.20 EWM23288.1 - 2.5e-51 173.5 0.0 4.7e-51 172.6 0.0 1.4 1 0 0 1 1 1 1 GTP cyclohydrolase II LRR_6 PF13516.6 EWM23289.1 - 4e-19 67.0 21.1 0.19 11.9 0.0 13.4 15 0 0 15 15 15 7 Leucine Rich repeat LRR_4 PF12799.7 EWM23289.1 - 5.6e-10 39.3 15.0 4.5 7.8 0.0 11.1 9 4 3 12 12 12 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EWM23289.1 - 7.8e-08 32.0 16.5 0.15 11.8 0.3 10.5 9 2 1 10 10 10 2 Leucine rich repeat LRR_1 PF00560.33 EWM23289.1 - 7.7e-06 25.8 17.2 28 5.8 0.0 11.1 13 1 1 14 14 14 1 Leucine Rich Repeat Pet191_N PF10203.9 EWM23290.1 - 6.5e-18 64.8 5.0 7.3e-18 64.6 5.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CLP_protease PF00574.23 EWM23292.1 - 3.6e-28 98.7 0.0 5.3e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Clp protease AMP-binding PF00501.28 EWM23293.1 - 3.4e-20 72.0 0.1 4.3e-20 71.7 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme BTB PF00651.31 EWM23294.1 - 2.9e-09 37.1 0.0 6e-09 36.1 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain F-box-like PF12937.7 EWM23296.1 - 0.00076 19.3 0.1 0.0019 18.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like Cmc1 PF08583.10 EWM23297.1 - 5.7e-16 58.3 2.7 7.4e-16 57.9 2.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CcdA PF07362.12 EWM23297.1 - 0.008 16.6 0.2 0.3 11.5 0.0 2.1 2 0 0 2 2 2 1 Post-segregation antitoxin CcdA NDUF_B7 PF05676.13 EWM23297.1 - 0.025 14.3 1.0 0.037 13.8 1.0 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CHCH PF06747.13 EWM23297.1 - 0.045 13.9 3.4 0.17 12.1 2.4 2.2 1 1 1 2 2 2 0 CHCH domain CX9C PF16860.5 EWM23297.1 - 0.078 13.0 2.0 0.13 12.3 2.0 1.4 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX17 PF05051.13 EWM23297.1 - 0.12 12.8 1.6 0.76 10.2 0.1 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) DUF3054 PF11255.8 EWM23298.1 - 2.6e-23 82.6 6.9 2.6e-23 82.6 6.9 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3054) FlxA PF14282.6 EWM23298.1 - 0.14 12.2 0.2 0.21 11.6 0.2 1.2 1 0 0 1 1 1 0 FlxA-like protein AMP-binding PF00501.28 EWM23300.1 - 9.8e-65 218.8 0.0 1.3e-64 218.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme EamA PF00892.20 EWM23301.1 - 3.5e-23 82.3 27.7 2.2e-13 50.5 7.5 2.2 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 EWM23301.1 - 0.059 12.7 7.9 0.015 14.6 2.2 2.1 1 1 0 2 2 2 0 Triose-phosphate Transporter family Peptidase_M50 PF02163.22 EWM23303.1 - 2.2e-05 23.8 8.2 0.0012 18.2 1.6 2.9 1 1 1 2 2 2 2 Peptidase family M50 Peptidase_M50B PF13398.6 EWM23303.1 - 0.00049 19.8 5.3 0.00049 19.8 5.3 2.6 1 1 1 2 2 2 1 Peptidase M50B-like ISET-FN3_linker PF16625.5 EWM23304.1 - 3.3 8.3 12.0 11 6.6 12.0 2.0 1 0 0 1 1 1 0 Unstructured linking region I-set and fnIII on Brother of CDO SNARE_assoc PF09335.11 EWM23305.1 - 1.9e-08 34.8 3.2 1.9e-08 34.8 3.2 2.5 2 1 1 3 3 3 1 SNARE associated Golgi protein Gemini_mov PF01708.16 EWM23305.1 - 0.49 10.2 2.7 5.8 6.8 0.4 3.0 3 0 0 3 3 3 0 Geminivirus putative movement protein MatE PF01554.18 EWM23306.1 - 1.8e-54 183.7 24.5 9.2e-30 103.4 5.7 2.9 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 EWM23306.1 - 3.5e-09 36.9 24.9 1.6e-06 28.3 3.3 3.7 4 0 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Cupin_8 PF13621.6 EWM23307.1 - 1.5e-47 162.4 0.0 2.6e-47 161.7 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EWM23307.1 - 1.7e-09 37.6 0.0 3.2e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 EWM23307.1 - 0.0085 16.5 0.0 0.023 15.1 0.0 1.7 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 EWM23307.1 - 0.09 12.5 0.0 0.65 9.8 0.0 2.4 3 0 0 3 3 3 0 Cupin domain MIF PF01187.18 EWM23308.1 - 4.6e-13 49.5 0.0 5.3e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.21 EWM23308.1 - 3.2e-07 30.2 0.0 0.0099 15.8 0.0 2.2 2 0 0 2 2 2 2 Tautomerase enzyme Tautomerase_2 PF14552.6 EWM23308.1 - 0.0088 16.1 0.0 0.024 14.7 0.0 1.6 1 1 0 2 2 2 1 Tautomerase enzyme Peptidase_M17_N PF02789.17 EWM23308.1 - 0.015 15.2 0.2 0.028 14.3 0.2 1.6 1 1 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain Ribosomal_S30AE PF02482.19 EWM23308.1 - 0.12 13.1 0.0 0.17 12.7 0.0 1.2 1 0 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein Esterase_phd PF10503.9 EWM23308.1 - 0.13 11.7 1.3 0.15 11.5 1.3 1.1 1 0 0 1 1 1 0 Esterase PHB depolymerase MIF PF01187.18 EWM23309.1 - 4.6e-13 49.5 0.0 5.3e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.21 EWM23309.1 - 3.2e-07 30.2 0.0 0.0099 15.8 0.0 2.2 2 0 0 2 2 2 2 Tautomerase enzyme Tautomerase_2 PF14552.6 EWM23309.1 - 0.0088 16.1 0.0 0.024 14.7 0.0 1.6 1 1 0 2 2 2 1 Tautomerase enzyme Peptidase_M17_N PF02789.17 EWM23309.1 - 0.015 15.2 0.2 0.028 14.3 0.2 1.6 1 1 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain Ribosomal_S30AE PF02482.19 EWM23309.1 - 0.12 13.1 0.0 0.17 12.7 0.0 1.2 1 0 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein Esterase_phd PF10503.9 EWM23309.1 - 0.13 11.7 1.3 0.15 11.5 1.3 1.1 1 0 0 1 1 1 0 Esterase PHB depolymerase PAE PF03283.13 EWM23310.1 - 8.9e-59 199.4 0.2 6e-50 170.4 0.3 2.2 2 0 0 2 2 2 2 Pectinacetylesterase Atg14 PF10186.9 EWM23311.1 - 3.7e-05 23.0 0.0 5.2e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Atg14 PF10186.9 EWM23312.1 - 3.7e-05 23.0 0.0 5.3e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 EWM23312.1 - 0.25 10.2 0.0 8.8 5.1 0.0 2.0 2 0 0 2 2 2 0 Vacuolar protein sorting 38 Chalcone_3 PF16036.5 EWM23313.1 - 1e-12 48.5 0.9 9.5e-12 45.3 0.9 1.9 1 1 0 1 1 1 1 Chalcone isomerase-like Chalcone PF02431.15 EWM23313.1 - 5.5e-09 35.7 0.6 7.5e-08 32.0 0.6 2.0 1 1 0 1 1 1 1 Chalcone-flavanone isomerase Chalcone_2 PF16035.5 EWM23313.1 - 2.3e-06 27.6 0.5 0.013 15.3 0.2 2.1 1 1 1 2 2 2 2 Chalcone isomerase like GlcNAc-1_reg PF18440.1 EWM23313.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Putative GlcNAc-1 phosphotransferase regulatory domain DUF1415 PF07209.12 EWM23316.1 - 4.4e-46 156.8 0.0 5.8e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1415) DUF5340 PF17275.2 EWM23317.1 - 0.01 15.9 0.2 0.032 14.3 0.2 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5340) PPR_2 PF13041.6 EWM23318.1 - 5.8e-94 308.2 6.5 5.5e-12 45.7 0.2 10.5 2 1 9 11 11 11 10 PPR repeat family PPR_1 PF12854.7 EWM23318.1 - 7e-74 243.2 0.0 1.3e-09 37.6 0.0 11.7 12 0 0 12 12 12 10 PPR repeat PPR PF01535.20 EWM23318.1 - 9e-69 223.1 16.2 7.3e-07 29.0 0.0 11.1 12 0 0 12 12 11 10 PPR repeat PPR_3 PF13812.6 EWM23318.1 - 4.9e-67 221.9 0.0 1.3e-11 44.4 0.0 7.1 3 2 6 9 9 9 9 Pentatricopeptide repeat domain PPR_long PF17177.4 EWM23318.1 - 4.6e-34 117.7 1.1 8.1e-11 41.7 0.0 4.5 1 1 3 4 4 4 4 Pentacotripeptide-repeat region of PRORP MRP-S27 PF10037.9 EWM23318.1 - 2.6e-07 29.8 0.0 0.82 8.5 0.0 4.4 2 1 1 4 4 4 3 Mitochondrial 28S ribosomal protein S27 TPR_7 PF13176.6 EWM23318.1 - 2.9e-05 23.8 3.1 17 5.8 0.0 6.9 8 0 0 8 8 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EWM23318.1 - 0.00064 19.9 1.9 23 5.3 0.1 5.8 6 2 1 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EWM23318.1 - 0.00072 20.0 7.7 0.74 10.4 0.1 5.7 4 2 4 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.6 EWM23318.1 - 0.0042 17.8 20.7 11 7.1 0.0 8.7 6 3 5 11 11 10 0 Tetratricopeptide repeat Ank_4 PF13637.6 EWM23318.1 - 0.02 15.5 0.4 15 6.3 0.0 3.9 4 1 1 5 5 4 0 Ankyrin repeats (many copies) DUF3322 PF11795.8 EWM23318.1 - 0.046 13.7 4.8 3.2 7.7 0.0 4.8 4 2 1 6 6 6 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Radical_SAM PF04055.21 EWM23318.1 - 0.059 13.7 0.0 1.2 9.5 0.0 2.6 1 1 0 2 2 2 0 Radical SAM superfamily TPR_2 PF07719.17 EWM23318.1 - 0.076 13.2 7.6 28 5.2 0.0 6.1 9 0 0 9 9 6 0 Tetratricopeptide repeat SNAP PF14938.6 EWM23318.1 - 0.18 11.2 0.1 2.3 7.5 0.1 2.4 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP Glyco_trans_4_3 PF12000.8 EWM23318.1 - 0.19 11.4 0.3 1.5e+02 2.0 0.0 4.3 5 1 1 6 6 6 0 Glycosyl transferase family 4 group TPR_1 PF00515.28 EWM23318.1 - 1.4 8.8 5.8 21 5.1 0.0 5.1 7 0 0 7 7 7 0 Tetratricopeptide repeat Cupin_4 PF08007.12 EWM23319.1 - 1.7e-16 60.6 0.1 1.8e-13 50.6 0.0 3.2 1 1 1 2 2 2 2 Cupin superfamily protein MMtag PF10159.9 EWM23320.1 - 1.4e-29 102.2 3.7 1.4e-29 102.2 3.7 2.7 2 1 0 2 2 2 1 Multiple myeloma tumor-associated Med19 PF10278.9 EWM23320.1 - 0.45 10.4 15.6 1 9.2 15.6 1.6 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Peptidase_S49_N PF08496.10 EWM23320.1 - 2 8.5 10.7 4.1 7.4 10.7 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal MMtag PF10159.9 EWM23321.1 - 0.0032 17.7 0.4 0.0032 17.7 0.4 3.0 2 1 0 2 2 2 1 Multiple myeloma tumor-associated Med19 PF10278.9 EWM23321.1 - 0.17 11.8 15.1 0.37 10.7 15.1 1.6 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Peptidase_S49_N PF08496.10 EWM23321.1 - 0.5 10.4 9.6 1 9.4 9.6 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Rrn6 PF10214.9 EWM23321.1 - 1.1 7.6 8.2 1.4 7.3 8.2 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Rota_VP2 PF05087.12 EWM23321.1 - 8.7 4.3 6.5 14 3.7 6.5 1.2 1 0 0 1 1 1 0 Rotavirus VP2 protein MMtag PF10159.9 EWM23322.1 - 1.3e-29 102.3 3.7 1.3e-29 102.3 3.7 2.7 2 1 0 2 2 2 1 Multiple myeloma tumor-associated Med19 PF10278.9 EWM23322.1 - 0.4 10.6 15.6 1 9.3 15.6 1.7 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Peptidase_S49_N PF08496.10 EWM23322.1 - 2 8.5 10.7 4 7.5 10.7 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal ABC2_membrane PF01061.24 EWM23323.1 - 1.3e-28 99.9 22.0 2e-28 99.3 22.0 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EWM23323.1 - 1.9e-25 90.0 0.0 2.9e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EWM23323.1 - 1.4e-06 28.4 0.1 0.0013 18.6 0.0 2.4 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EWM23323.1 - 5.2e-05 22.8 0.0 8.8e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EWM23323.1 - 0.00016 21.6 0.2 0.00038 20.4 0.2 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EWM23323.1 - 0.00034 21.0 0.0 0.00074 19.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 EWM23323.1 - 0.00052 19.6 0.0 0.00098 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain PDR_CDR PF06422.12 EWM23323.1 - 0.0038 17.1 0.5 0.03 14.2 0.0 2.5 2 0 0 2 2 2 1 CDR ABC transporter AAA_22 PF13401.6 EWM23323.1 - 0.014 15.7 0.1 0.035 14.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EWM23323.1 - 0.029 14.3 0.5 0.064 13.2 0.2 1.8 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 EWM23323.1 - 0.034 14.6 0.0 0.14 12.6 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EWM23323.1 - 0.091 12.5 0.1 0.4 10.4 0.1 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein PduV-EutP PF10662.9 EWM23323.1 - 0.18 11.6 0.1 0.42 10.4 0.1 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 EWM23323.1 - 0.22 11.3 0.3 0.45 10.3 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SPC25 PF06703.11 EWM23323.1 - 0.34 10.7 3.1 0.79 9.5 3.1 1.6 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) ABC2_membrane_3 PF12698.7 EWM23323.1 - 2.1 7.4 22.4 0.31 10.1 17.5 2.1 1 1 1 2 2 2 0 ABC-2 family transporter protein DnaJ_CXXCXGXG PF00684.19 EWM23324.1 - 0.0012 19.2 11.6 0.0033 17.7 11.6 1.8 1 1 0 1 1 1 1 DnaJ central domain zf-RING_9 PF13901.6 EWM23324.1 - 6.8 6.6 8.6 16 5.4 8.6 1.5 1 1 0 1 1 1 0 Putative zinc-RING and/or ribbon Anti-TRAP PF15777.5 EWM23324.1 - 9.4 6.3 12.7 2.8 7.9 3.0 3.0 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Herpes_UL92 PF03048.14 EWM23325.1 - 0.027 14.2 1.1 0.036 13.9 1.1 1.6 1 1 0 1 1 1 0 UL92 family START PF01852.19 EWM23326.1 - 5.8e-16 58.5 0.0 1.1e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 START domain Death PF00531.22 EWM23326.1 - 0.033 14.3 0.4 0.033 14.3 0.4 2.6 2 0 0 2 2 2 0 Death domain Apolipoprotein PF01442.18 EWM23326.1 - 0.99 9.3 25.2 2.7e+02 1.3 25.2 2.2 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain TipAS PF07739.13 EWM23326.1 - 1.3 9.6 6.3 13 6.3 0.1 3.1 1 1 2 3 3 3 0 TipAS antibiotic-recognition domain TPR_MLP1_2 PF07926.12 EWM23326.1 - 2.4 8.2 16.3 0.037 14.1 4.1 2.5 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein CBM49 PF09478.10 EWM23327.1 - 0.00014 22.1 0.0 0.1 12.9 0.0 2.2 2 0 0 2 2 2 2 Carbohydrate binding domain CBM49 YL1 PF05764.13 EWM23327.1 - 0.98 9.5 34.1 5.1 7.1 26.4 2.3 2 0 0 2 2 2 0 YL1 nuclear protein CDC45 PF02724.14 EWM23327.1 - 5.5 5.2 18.1 0.25 9.6 9.1 2.0 2 0 0 2 2 2 0 CDC45-like protein SDA1 PF05285.12 EWM23327.1 - 6.7 6.0 30.2 6.9 6.0 23.1 2.1 2 0 0 2 2 2 0 SDA1 DUF647 PF04884.14 EWM23329.1 - 1.9e-74 250.4 1.6 2.5e-74 250.0 1.6 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis OTU PF02338.19 EWM23330.1 - 2.3e-11 44.3 0.0 4.3e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EWM23330.1 - 0.00052 19.5 0.0 0.32 10.4 0.2 2.2 1 1 1 2 2 2 2 Peptidase C65 Otubain Pkinase PF00069.25 EWM23331.1 - 3.5e-27 95.4 0.0 4.3e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM23331.1 - 5.9e-17 61.8 0.0 7.4e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EWM23331.1 - 4.9e-09 35.4 0.3 6.8e-09 35.0 0.3 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EWM23331.1 - 4e-05 23.7 0.0 8.8e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family RCC1 PF00415.18 EWM23332.1 - 4e-59 197.0 25.0 4.7e-14 52.7 0.2 8.0 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EWM23332.1 - 1.5e-32 110.7 33.1 2e-07 30.6 3.9 8.1 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat NUP50 PF08911.11 EWM23332.1 - 0.03 15.0 0.1 0.096 13.4 0.1 1.8 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) RNase_T PF00929.24 EWM23333.1 - 0.0044 17.6 0.1 0.02 15.5 0.1 2.0 1 1 0 1 1 1 1 Exonuclease zf_CCCH_4 PF18345.1 EWM23333.1 - 0.005 16.9 1.5 0.0094 16.0 1.5 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 EWM23333.1 - 0.0071 16.1 0.4 0.014 15.2 0.4 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 EWM23333.1 - 0.0098 15.8 0.4 0.019 14.9 0.4 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EWM23333.1 - 0.13 13.0 2.0 1.1 10.0 0.0 2.9 3 0 0 3 3 3 0 Torus domain LCAT PF02450.15 EWM23334.1 - 8.5e-45 153.6 0.0 2.8e-39 135.4 0.0 2.1 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 EWM23334.1 - 6e-06 25.7 0.0 1.7e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EWM23334.1 - 0.00012 22.8 6.6 0.00012 22.8 6.6 2.6 1 1 3 4 4 4 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EWM23334.1 - 0.00051 19.8 0.0 0.00079 19.2 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Esterase PF00756.20 EWM23334.1 - 0.016 14.8 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Palm_thioest PF02089.15 EWM23334.1 - 0.017 15.0 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF676 PF05057.14 EWM23334.1 - 0.079 12.5 0.1 0.16 11.5 0.0 1.4 2 0 0 2 2 2 0 Putative serine esterase (DUF676) DUF900 PF05990.12 EWM23334.1 - 0.17 11.4 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Lipase_3 PF01764.25 EWM23334.1 - 0.17 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Pkinase PF00069.25 EWM23335.1 - 8.1e-76 254.9 0.0 1.2e-75 254.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM23335.1 - 1.3e-32 113.1 0.0 2.8e-32 112.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 EWM23335.1 - 2.5e-25 88.7 1.8 4.2e-11 43.1 0.9 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 EWM23335.1 - 2.3e-24 83.1 0.3 1.5e-05 24.2 0.2 5.0 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EWM23335.1 - 2.6e-20 70.6 2.6 3.3e-05 23.5 0.0 5.0 4 1 1 5 5 4 3 EF-hand domain EF-hand_5 PF13202.6 EWM23335.1 - 4.1e-18 64.0 3.6 7.5e-06 25.2 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EWM23335.1 - 2.3e-11 43.4 3.4 7e-07 29.0 0.5 3.9 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EWM23335.1 - 1.1e-06 28.9 0.1 0.0029 17.9 0.1 2.7 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Kdo PF06293.14 EWM23335.1 - 0.00019 20.8 0.1 0.00051 19.5 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_9 PF14658.6 EWM23335.1 - 0.00044 20.5 0.5 2.6 8.5 0.0 3.4 2 1 0 2 2 2 2 EF-hand domain APH PF01636.23 EWM23335.1 - 0.0023 17.9 0.3 0.013 15.4 0.0 2.3 2 2 0 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EWM23335.1 - 0.0039 16.8 0.1 0.0076 15.9 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase EFhand_Ca_insen PF08726.10 EWM23335.1 - 0.0042 17.1 0.1 0.18 11.9 0.0 2.6 2 0 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 EWM23335.1 - 0.011 16.6 0.1 0.082 13.8 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain DUF445 PF04286.12 EWM23335.1 - 0.016 15.0 0.1 0.038 13.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF445) EcKinase PF02958.20 EWM23335.1 - 0.018 14.4 0.4 0.05 12.9 0.0 1.9 3 0 0 3 3 3 0 Ecdysteroid kinase Kinase-like PF14531.6 EWM23335.1 - 0.033 13.5 0.1 0.57 9.4 0.0 2.7 2 1 1 3 3 3 0 Kinase-like Caleosin PF05042.13 EWM23335.1 - 0.2 11.6 0.8 18 5.2 0.2 2.8 2 1 0 3 3 3 0 Caleosin related protein TYW3 PF02676.14 EWM23337.1 - 1.6e-49 168.1 0.0 2.4e-49 167.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase TYW3 Met_10 PF02475.16 EWM23337.1 - 8.7e-26 90.9 0.0 1.4e-25 90.3 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Kelch_4 PF13418.6 EWM23337.1 - 9.4e-09 35.1 7.7 0.012 15.6 0.1 5.0 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 EWM23337.1 - 1.9e-07 30.9 0.0 0.23 11.5 0.0 5.3 6 0 0 6 6 6 2 Kelch motif Kelch_3 PF13415.6 EWM23337.1 - 1.5e-05 25.1 1.4 0.017 15.4 0.0 4.3 3 0 0 3 3 3 1 Galactose oxidase, central domain MTS PF05175.14 EWM23337.1 - 0.00028 20.5 0.0 0.00062 19.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Kelch_6 PF13964.6 EWM23337.1 - 0.0016 18.7 3.1 5.5 7.4 0.0 4.7 4 1 1 5 5 5 1 Kelch motif Kelch_2 PF07646.15 EWM23337.1 - 0.0081 16.1 6.5 31 4.7 0.1 5.1 5 0 0 5 5 5 0 Kelch motif Methyltransf_15 PF09445.10 EWM23337.1 - 0.012 15.2 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 EWM23337.1 - 0.11 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 EWM23337.1 - 0.14 12.9 0.0 0.33 11.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltrans_SAM PF10672.9 EWM23337.1 - 0.19 10.9 0.0 0.38 9.9 0.0 1.4 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase DUF3067 PF11267.8 EWM23338.1 - 1.6e-25 89.5 0.1 2.2e-25 89.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3067) CPSase_L_D2 PF02786.17 EWM23339.1 - 6.6e-72 241.4 0.0 1e-71 240.8 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EWM23339.1 - 4.7e-44 149.4 0.0 8.7e-44 148.6 0.0 1.4 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EWM23339.1 - 2.4e-35 120.9 0.0 9e-35 119.0 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EWM23339.1 - 1.1e-17 63.6 0.5 2.7e-17 62.4 0.5 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EWM23339.1 - 3.1e-08 33.4 0.0 7.1e-08 32.2 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 EWM23339.1 - 2.2e-06 27.4 1.7 0.0003 20.6 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 EWM23339.1 - 7.2e-06 25.7 0.0 1.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 EWM23339.1 - 0.0065 17.1 0.8 7 7.4 0.0 2.8 2 0 0 2 2 2 2 HlyD family secretion protein TPR_1 PF00515.28 EWM23341.1 - 3.4e-17 61.5 0.0 0.00079 19.1 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 EWM23341.1 - 5.1e-16 57.4 1.2 0.00069 19.5 0.1 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 EWM23341.1 - 1.4e-15 56.6 0.0 1.1e-05 25.1 0.0 4.3 4 0 0 4 4 4 2 TPR repeat TPR_12 PF13424.6 EWM23341.1 - 2.9e-12 46.7 3.5 0.00074 19.8 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EWM23341.1 - 2.3e-11 44.2 3.8 8.2e-07 29.6 1.4 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EWM23341.1 - 6.5e-10 39.0 7.7 0.02 15.7 0.4 6.5 4 1 3 7 7 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 EWM23341.1 - 1.1e-08 34.6 0.1 0.0071 16.5 0.0 5.0 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 EWM23341.1 - 1e-07 32.0 3.0 0.0016 18.5 0.3 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EWM23341.1 - 7.7e-07 28.7 2.5 0.013 15.5 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 EWM23341.1 - 0.00031 20.5 3.6 0.31 11.0 0.8 4.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 EWM23341.1 - 0.00055 20.1 0.1 2.3 8.8 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EWM23341.1 - 0.00071 20.0 0.3 0.31 11.6 0.2 2.9 2 1 0 3 3 2 1 Tetratricopeptide repeat FAT PF02259.23 EWM23341.1 - 0.0037 16.5 0.0 0.0073 15.6 0.0 1.4 2 0 0 2 2 2 1 FAT domain PaaX_C PF08223.11 EWM23341.1 - 0.014 15.6 0.7 17 5.8 0.0 3.3 3 0 0 3 3 3 0 PaaX-like protein C-terminal domain TPR_15 PF13429.6 EWM23341.1 - 0.02 14.1 0.2 0.16 11.2 0.1 2.4 2 1 1 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 EWM23341.1 - 0.19 12.2 2.7 4.7 7.6 1.9 2.7 2 1 1 3 3 3 0 Bacterial transcriptional activator domain TPR_6 PF13174.6 EWM23341.1 - 1.4 9.7 4.1 6.1 7.7 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EWM23342.1 - 1.8e-15 56.0 0.5 0.00059 19.6 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 EWM23342.1 - 2.9e-15 55.6 0.0 7.7e-06 25.5 0.0 3.4 3 0 0 3 3 3 3 TPR repeat TPR_2 PF07719.17 EWM23342.1 - 3e-14 51.9 1.3 0.00051 20.0 0.1 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 EWM23342.1 - 4.5e-11 42.9 3.6 0.00054 20.2 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EWM23342.1 - 7.6e-09 36.1 2.9 4.9e-07 30.3 1.2 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 EWM23342.1 - 1.1e-07 31.8 1.8 0.0056 16.8 0.1 3.5 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EWM23342.1 - 3.3e-07 29.9 2.5 0.0095 15.9 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EWM23342.1 - 6.8e-07 29.0 0.3 0.0052 16.9 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EWM23342.1 - 1.4e-05 25.5 7.3 0.013 16.3 0.5 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 EWM23342.1 - 0.00025 20.8 3.5 0.23 11.4 0.7 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 EWM23342.1 - 0.00052 20.2 0.1 1.7 9.2 0.0 3.5 4 0 0 4 4 3 2 Tetratricopeptide repeat FAT PF02259.23 EWM23342.1 - 0.0033 16.7 0.0 0.0046 16.2 0.0 1.2 1 0 0 1 1 1 1 FAT domain TPR_19 PF14559.6 EWM23342.1 - 0.067 13.7 0.7 0.23 12.0 0.2 2.2 2 1 0 2 2 1 0 Tetratricopeptide repeat PaaX_C PF08223.11 EWM23342.1 - 0.11 12.7 0.2 12 6.2 0.0 2.4 2 0 0 2 2 2 0 PaaX-like protein C-terminal domain MIT PF04212.18 EWM23342.1 - 0.18 11.9 1.4 83 3.4 0.0 3.6 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 EWM23342.1 - 0.89 10.3 3.3 4.5 8.1 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Syja_N PF02383.18 EWM23344.1 - 1.3e-57 195.6 0.0 1.7e-57 195.2 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain PAP1 PF08601.10 EWM23344.1 - 1.1 8.9 6.1 1.9 8.1 6.1 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 TolA_bind_tri PF16331.5 EWM23347.1 - 0.068 13.2 11.2 0.43 10.7 1.4 2.9 2 0 0 2 2 2 0 TolA binding protein trimerisation SAM_KSR1 PF13543.6 EWM23347.1 - 0.16 12.1 3.8 0.11 12.6 0.4 2.3 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 HlyD_2 PF12700.7 EWM23347.1 - 0.31 9.7 0.8 0.6 8.8 0.6 1.4 2 0 0 2 2 2 0 HlyD family secretion protein FAM76 PF16046.5 EWM23347.1 - 0.45 9.8 21.6 0.18 11.1 1.1 2.7 2 1 1 3 3 3 0 FAM76 protein FlaC_arch PF05377.11 EWM23347.1 - 0.66 10.4 6.8 6.7 7.2 0.7 3.7 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 EWM23347.1 - 1.1 8.0 42.3 0.61 8.9 12.8 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Snapin_Pallidin PF14712.6 EWM23347.1 - 2.3 8.7 14.8 3.7 8.0 2.3 3.6 2 1 1 3 3 3 0 Snapin/Pallidin NPV_P10 PF05531.12 EWM23347.1 - 4.7 7.8 12.6 5.3 7.6 3.5 3.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF3450 PF11932.8 EWM23347.1 - 9.7 5.4 44.9 1.8 7.8 10.0 3.5 2 1 0 3 3 3 0 Protein of unknown function (DUF3450) IF-2B PF01008.17 EWM23347.1 - 10 5.3 16.0 0.093 11.9 7.4 1.8 2 0 0 2 2 2 0 Initiation factor 2 subunit family 2OG-FeII_Oxy_2 PF13532.6 EWM23348.1 - 2.9e-08 34.1 0.1 4.2e-08 33.6 0.1 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UPF0114 PF03350.16 EWM23349.1 - 0.1 12.8 0.2 0.23 11.7 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein family, UPF0114 SAP18 PF06487.12 EWM23350.1 - 2e-29 102.5 0.0 2.6e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Asn_synthase PF00733.21 EWM23351.1 - 2.8e-95 320.0 0.1 1.6e-57 195.8 0.1 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 EWM23351.1 - 1.7e-38 131.3 0.0 3.6e-38 130.2 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EWM23351.1 - 2.5e-30 105.4 0.0 8.8e-30 103.6 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EWM23351.1 - 6.7e-08 32.2 0.1 1.4e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 EWM23351.1 - 0.24 10.5 0.0 0.35 10.0 0.0 1.2 1 0 0 1 1 1 0 NAD synthase Dynamin_M PF01031.20 EWM23355.1 - 8e-100 333.7 0.0 1.6e-99 332.7 0.0 1.5 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 EWM23355.1 - 1.5e-55 187.8 0.0 2.3e-55 187.2 0.0 1.3 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EWM23355.1 - 0.0005 20.1 0.0 0.0018 18.3 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EWM23355.1 - 0.16 11.3 0.1 16 4.8 0.0 2.3 2 0 0 2 2 2 0 AIG1 family Paf1 PF03985.13 EWM23356.1 - 2.1e-12 46.8 0.0 3.6e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Paf1 Paf1 PF03985.13 EWM23357.1 - 2.1e-12 46.8 0.0 3.6e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Paf1 RNA_pol_Rpb6 PF01192.22 EWM23358.1 - 6.1e-15 54.9 0.2 1.1e-14 54.1 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 Erv26 PF04148.13 EWM23359.1 - 4e-41 141.1 11.9 8.2e-41 140.1 11.9 1.5 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 Hist_deacetyl PF00850.19 EWM23360.1 - 8.1e-39 133.9 0.0 1.9e-38 132.7 0.0 1.5 1 1 0 1 1 1 1 Histone deacetylase domain GED PF02212.18 EWM23361.1 - 1.2e-26 92.7 2.9 1.4e-26 92.5 2.9 1.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain CelTOS PF18659.1 EWM23361.1 - 0.04 14.4 0.6 0.073 13.5 0.6 1.5 1 1 0 1 1 1 0 Cell-traversal protein for ookinetes and sporozoites DUF3506 PF12014.8 EWM23362.1 - 8.8e-08 32.2 0.0 3e-07 30.5 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) RNA_pol_L PF01193.24 EWM23363.1 - 1.9e-22 78.4 0.0 2.8e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_A_bac PF01000.26 EWM23363.1 - 6.7e-21 74.8 0.0 2.1e-20 73.2 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain Fer4_7 PF12838.7 EWM23363.1 - 0.031 14.8 0.2 0.073 13.7 0.2 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 EWM23363.1 - 0.086 13.0 0.2 0.18 12.0 0.2 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain RNA_pol_L_2 PF13656.6 EWM23363.1 - 0.14 11.9 0.0 15 5.5 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain UPF0225 PF17775.1 EWM23364.1 - 2.1e-16 60.6 0.0 3e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 UPF0225 domain SEC-C PF02810.15 EWM23364.1 - 0.0029 17.5 7.1 0.0044 16.9 7.1 1.3 1 0 0 1 1 1 1 SEC-C motif Dynamin_N PF00350.23 EWM23365.1 - 5.9e-15 55.7 0.0 3.5e-14 53.2 0.0 2.3 2 1 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 EWM23365.1 - 6.9e-11 41.9 0.1 1.5e-09 37.5 0.0 2.4 2 1 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 EWM23365.1 - 0.0013 18.8 0.0 0.094 12.8 0.0 3.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EWM23365.1 - 0.0015 18.5 0.0 0.5 10.2 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase GED PF02212.18 EWM23365.1 - 0.0089 16.2 2.8 0.01 16.0 0.3 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain AAA_29 PF13555.6 EWM23365.1 - 0.0093 15.7 0.1 0.023 14.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF1729 PF08354.10 EWM23365.1 - 0.069 12.0 0.0 0.28 10.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1729) AAA_23 PF13476.6 EWM23365.1 - 0.07 13.6 0.1 0.07 13.6 0.1 2.4 2 2 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EWM23365.1 - 0.097 13.2 0.0 0.37 11.3 0.0 2.0 1 0 0 1 1 1 0 ABC transporter Med9 PF07544.13 EWM23365.1 - 0.1 12.7 0.3 3.8 7.7 0.1 3.1 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 PduV-EutP PF10662.9 EWM23365.1 - 0.18 11.5 0.1 19 5.0 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 EWM23366.1 - 1.3e-19 70.9 0.0 2.8e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EWM23366.1 - 1.6e-15 57.1 0.1 5.4e-15 55.4 0.1 1.8 1 1 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 EWM23366.1 - 6.7e-05 22.9 0.1 0.0008 19.5 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase GED PF02212.18 EWM23366.1 - 0.00056 20.0 1.5 0.0017 18.5 1.5 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain PduV-EutP PF10662.9 EWM23366.1 - 0.0038 17.0 0.1 1 9.1 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.6 EWM23366.1 - 0.012 15.5 0.0 0.063 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 EWM23366.1 - 0.039 14.5 0.0 0.19 12.2 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 EWM23366.1 - 0.042 14.2 0.0 0.23 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 EWM23366.1 - 0.047 13.6 0.0 0.63 9.9 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase CBS PF00571.28 EWM23366.1 - 0.17 12.4 0.1 0.48 10.9 0.1 1.8 1 0 0 1 1 1 0 CBS domain Aminotran_1_2 PF00155.21 EWM23367.1 - 4.5e-46 157.7 0.0 5.4e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EWM23367.1 - 0.0057 15.2 0.0 0.0085 14.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme LPD15 PF18828.1 EWM23367.1 - 0.045 13.6 0.0 4.3 7.3 0.0 2.4 2 0 0 2 2 2 0 Large polyvalent-protein-associated domain 15 WD40 PF00400.32 EWM23368.1 - 2.2e-40 135.9 16.9 4.1e-07 30.6 0.1 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM23368.1 - 9.2e-16 57.9 0.4 0.0017 18.6 0.0 5.7 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EWM23368.1 - 0.0069 16.3 0.0 1.2 9.0 0.0 2.8 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EWM23368.1 - 0.091 12.1 0.0 7.8 5.7 0.0 2.8 3 0 0 3 3 3 0 WD40-like domain PALB2_WD40 PF16756.5 EWM23368.1 - 0.12 11.3 2.5 0.15 11.0 0.5 2.1 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain PQQ_3 PF13570.6 EWM23368.1 - 1.1 9.9 12.1 46 4.7 0.1 6.0 6 0 0 6 6 6 0 PQQ-like domain LMWPc PF01451.21 EWM23369.1 - 1.8e-30 106.2 0.1 2e-29 102.8 0.1 2.0 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase NT-C2 PF10358.9 EWM23370.1 - 7.9e-09 35.4 0.2 1.6e-08 34.4 0.2 1.5 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins ORF11CD3 PF10549.9 EWM23370.1 - 0.053 13.6 0.7 3.8 7.7 0.0 3.6 3 0 0 3 3 3 0 ORF11CD3 domain DUF2373 PF10180.9 EWM23371.1 - 1.1e-12 47.5 0.1 2.2e-12 46.6 0.1 1.6 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) NOT2_3_5 PF04153.18 EWM23371.1 - 0.11 12.6 0.1 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 NOT2 / NOT3 / NOT5 family TPR_MLP1_2 PF07926.12 EWM23372.1 - 5.1e-08 33.0 55.1 2.1e-05 24.6 26.2 2.5 1 1 2 3 3 3 3 TPR/MLP1/MLP2-like protein Seryl_tRNA_N PF02403.22 EWM23372.1 - 4.2e-05 23.7 13.2 4.2e-05 23.7 13.2 3.7 1 1 3 4 4 4 1 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.11 EWM23372.1 - 8.2e-05 21.6 14.5 8.2e-05 21.6 14.5 2.3 1 1 1 2 2 2 1 Spc7 kinetochore protein CALCOCO1 PF07888.11 EWM23372.1 - 0.012 14.5 43.8 0.01 14.7 28.1 2.1 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF3584 PF12128.8 EWM23372.1 - 0.012 13.1 34.4 0.018 12.6 34.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Filament PF00038.21 EWM23372.1 - 0.013 15.1 41.8 0.12 11.9 13.7 3.0 1 1 3 4 4 4 0 Intermediate filament protein BLOC1_2 PF10046.9 EWM23372.1 - 0.017 15.4 6.9 0.017 15.4 6.9 3.6 1 1 0 2 2 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GAS PF13851.6 EWM23372.1 - 0.03 13.7 46.5 0.16 11.3 32.3 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Pox_A_type_inc PF04508.12 EWM23372.1 - 0.033 14.0 0.1 0.033 14.0 0.1 4.3 5 0 0 5 5 4 0 Viral A-type inclusion protein repeat Tropomyosin PF00261.20 EWM23372.1 - 0.049 13.0 51.6 0.18 11.2 7.3 3.8 1 1 2 3 3 3 0 Tropomyosin DUF948 PF06103.11 EWM23372.1 - 0.055 13.7 1.4 0.055 13.7 1.4 4.0 1 1 1 3 3 2 0 Bacterial protein of unknown function (DUF948) Fez1 PF06818.15 EWM23372.1 - 0.11 12.9 44.1 0.081 13.4 20.3 2.6 1 1 1 2 2 2 0 Fez1 FlaC_arch PF05377.11 EWM23372.1 - 0.13 12.6 27.8 1.4 9.3 3.1 5.6 3 2 3 6 6 6 0 Flagella accessory protein C (FlaC) KELK PF15796.5 EWM23372.1 - 0.16 12.4 44.3 0.23 11.9 5.4 4.2 1 1 3 4 4 4 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Golgin_A5 PF09787.9 EWM23372.1 - 0.3 10.5 43.2 0.13 11.7 31.2 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 HMMR_N PF15905.5 EWM23372.1 - 0.31 10.5 45.9 1.4 8.3 27.7 2.9 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal DUF4407 PF14362.6 EWM23372.1 - 0.35 10.2 39.5 1.2 8.5 16.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Tropomyosin_1 PF12718.7 EWM23372.1 - 0.46 10.6 54.1 2.8 8.1 18.7 4.1 1 1 3 4 4 4 0 Tropomyosin like PhoU PF01895.19 EWM23372.1 - 0.47 10.9 19.2 3.6 8.1 1.9 3.5 2 1 1 3 3 3 0 PhoU domain MscS_porin PF12795.7 EWM23372.1 - 0.68 9.4 45.9 0.56 9.7 9.2 2.3 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Lebercilin PF15619.6 EWM23372.1 - 1.1 8.9 50.9 0.12 12.1 29.2 2.4 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease MPS2 PF17060.5 EWM23372.1 - 1.3 8.2 30.8 0.02 14.2 12.5 2.2 1 1 1 2 2 2 0 Monopolar spindle protein 2 UPF0242 PF06785.11 EWM23372.1 - 1.5 8.9 46.1 0.98 9.5 9.0 3.0 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Uds1 PF15456.6 EWM23372.1 - 1.5 9.0 36.6 0.54 10.4 11.8 3.7 1 1 1 3 3 3 0 Up-regulated During Septation ATG16 PF08614.11 EWM23372.1 - 1.8 8.8 50.5 0.047 13.9 10.6 3.2 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) HOOK PF05622.12 EWM23372.1 - 1.9 6.6 43.5 0.04 12.1 17.1 2.0 1 1 1 2 2 2 0 HOOK protein CENP-F_leu_zip PF10473.9 EWM23372.1 - 2 8.4 51.1 0.93 9.5 15.7 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Jnk-SapK_ap_N PF09744.9 EWM23372.1 - 2.3 8.5 48.5 0.049 13.8 15.5 3.2 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 ERM PF00769.19 EWM23372.1 - 2.3 8.0 54.9 6.2 6.6 55.0 1.7 1 1 0 1 1 1 0 Ezrin/radixin/moesin family ADIP PF11559.8 EWM23372.1 - 3.4 7.7 46.4 0.2 11.7 6.0 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding NPV_P10 PF05531.12 EWM23372.1 - 4.8 7.7 17.5 19 5.8 6.9 4.7 1 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.6 EWM23372.1 - 5.5 5.5 40.2 0.18 10.4 22.8 2.1 1 1 2 3 3 3 0 AAA domain FAM184 PF15665.5 EWM23372.1 - 6.8 6.4 42.8 14 5.4 42.7 1.6 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B Uso1_p115_C PF04871.13 EWM23372.1 - 8 6.9 56.1 66 3.9 17.1 3.5 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region SSB PF00436.25 EWM23373.1 - 2.9e-23 81.9 0.1 4.4e-23 81.3 0.1 1.3 1 0 0 1 1 1 1 Single-strand binding protein family ADH_N PF08240.12 EWM23374.1 - 8.3e-31 106.1 0.2 1.5e-30 105.3 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EWM23374.1 - 1e-15 57.9 0.1 1.8e-15 57.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EWM23374.1 - 0.0019 17.7 0.4 0.0035 16.9 0.4 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Pyr_redox_3 PF13738.6 EWM23374.1 - 0.34 10.1 0.8 1.3 8.2 0.1 2.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ANAPC_CDC26 PF10471.9 EWM23376.1 - 2e-12 47.8 0.1 2.2e-12 47.6 0.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 Proteasome PF00227.26 EWM23378.1 - 7e-46 156.1 1.3 7.9e-46 155.9 1.3 1.0 1 0 0 1 1 1 1 Proteasome subunit DEAD PF00270.29 EWM23379.1 - 5.7e-32 110.9 0.0 4.9e-19 68.8 0.0 2.8 2 1 1 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EWM23379.1 - 9e-23 80.7 0.1 3.5e-22 78.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EWM23379.1 - 0.00026 20.3 0.0 0.00026 20.3 0.0 2.2 2 1 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase FXR_C3 PF16097.5 EWM23379.1 - 0.29 11.8 3.7 0.56 10.9 3.5 1.6 1 1 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 3 CMS1 PF14617.6 EWM23379.1 - 0.84 8.9 0.0 0.84 8.9 0.0 3.1 2 1 1 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit DUF4551 PF15087.6 EWM23379.1 - 4.4 6.0 11.6 5.6 5.7 11.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Cpn10 PF00166.21 EWM23380.1 - 3.8e-07 30.1 0.0 5e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Ank_2 PF12796.7 EWM23384.1 - 2.2e-14 53.8 0.5 3.7e-14 53.1 0.5 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EWM23384.1 - 2.9e-11 42.6 1.9 0.00089 19.5 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 EWM23384.1 - 6.4e-11 42.6 0.4 2.3e-05 24.8 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EWM23384.1 - 1e-09 38.3 0.3 0.004 17.5 0.1 3.2 2 0 0 2 2 2 2 Ankyrin repeat WW PF00397.26 EWM23384.1 - 5.2e-09 36.0 1.0 6.5e-09 35.7 0.1 1.7 2 0 0 2 2 2 1 WW domain Ank_5 PF13857.6 EWM23384.1 - 1.5e-08 34.8 2.4 4.3e-05 23.7 0.1 3.4 1 1 2 3 3 3 1 Ankyrin repeats (many copies) FAP PF07174.11 EWM23384.1 - 0.033 13.7 12.0 0.042 13.3 12.0 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF2967 PF11179.8 EWM23385.1 - 7.4 4.5 7.9 8.6 4.3 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) VRR_NUC PF08774.11 EWM23386.1 - 2.4e-05 24.3 0.1 4.2e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 VRR-NUC domain Vps26 PF03643.15 EWM23387.1 - 4.7e-110 366.9 0.6 5.9e-110 366.6 0.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 EWM23387.1 - 0.002 18.2 0.4 0.26 11.3 0.0 3.1 2 1 1 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EWM23387.1 - 0.0049 17.3 0.0 0.46 11.0 0.0 2.4 1 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Myb_DNA-binding PF00249.31 EWM23388.1 - 0.0074 16.5 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF2946 PF11162.8 EWM23388.1 - 0.048 14.3 0.1 0.096 13.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Semialdhyde_dhC PF02774.18 EWM23389.1 - 3.3e-45 154.4 0.0 4.3e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 EWM23389.1 - 1.3e-28 99.8 0.0 2.1e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EWM23389.1 - 0.0083 16.7 0.0 0.017 15.7 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Peptidase_C69 PF03577.15 EWM23390.1 - 4.6e-46 157.5 0.3 9.8e-39 133.4 0.1 2.4 2 1 0 2 2 2 2 Peptidase family C69 PUF PF00806.19 EWM23392.1 - 3.7e-52 171.2 1.4 4.3e-07 29.2 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat RTX_C PF08339.10 EWM23392.1 - 0.046 13.8 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 RTX C-terminal domain Mito_carr PF00153.27 EWM23393.1 - 1.2e-30 105.3 0.4 6.5e-11 42.0 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein LSM PF01423.22 EWM23394.1 - 5.1e-09 35.7 0.0 5.8e-06 25.9 0.0 2.3 2 0 0 2 2 2 2 LSM domain SRP-alpha_N PF04086.13 EWM23394.1 - 0.07 13.0 7.7 0.12 12.3 7.7 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal NifU PF01106.17 EWM23395.1 - 3.3e-23 81.6 0.7 1.5e-21 76.3 0.1 2.7 2 0 0 2 2 2 1 NifU-like domain DUF4456 PF14644.6 EWM23395.1 - 0.057 13.1 0.3 0.097 12.3 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) MAPEG PF01124.18 EWM23396.1 - 3.1e-16 59.5 0.9 4.1e-16 59.1 0.9 1.1 1 0 0 1 1 1 1 MAPEG family Phage_spike PF18715.1 EWM23396.1 - 0.026 14.6 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 Phage spike trimer DAO PF01266.24 EWM23398.1 - 2.8e-45 155.5 0.1 4.2e-45 154.9 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 EWM23398.1 - 7.6e-34 116.3 0.1 1.4e-33 115.5 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 EWM23398.1 - 2.8e-06 26.7 3.2 0.019 14.1 0.9 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 EWM23398.1 - 0.0029 17.0 1.8 0.017 14.5 0.4 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EWM23398.1 - 0.0031 16.8 0.3 2.6 7.2 0.1 2.5 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 EWM23398.1 - 0.014 14.7 0.1 0.089 12.0 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EWM23398.1 - 0.2 10.7 0.5 0.41 9.7 0.5 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 EWM23398.1 - 1.5 9.5 3.3 7.3 7.2 0.5 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DEC-1_N PF04625.13 EWM23399.1 - 0.0095 15.0 5.5 0.013 14.6 5.5 1.2 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region TCTP PF00838.17 EWM23400.1 - 1.1e-42 146.2 0.2 1.2e-42 146.0 0.2 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Dynein_C PF18199.1 EWM23402.1 - 2e-68 230.9 0.1 2.2e-68 230.7 0.1 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain DUF4807 PF16065.5 EWM23402.1 - 0.23 11.1 0.4 26 4.5 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4807) Peptidase_M48 PF01435.18 EWM23403.1 - 3.7e-19 69.3 0.0 1.9e-18 67.0 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 EWM23403.1 - 0.0088 15.3 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 1 BlaR1 peptidase M56 DUF212 PF02681.14 EWM23403.1 - 0.015 15.4 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 Divergent PAP2 family Exo70 PF03081.15 EWM23404.1 - 1.2e-37 129.8 0.0 2.9e-37 128.6 0.0 1.7 1 1 0 1 1 1 1 Exo70 exocyst complex subunit AAA_6 PF12774.7 EWM23405.1 - 3.3e-71 239.9 0.1 3.6e-71 239.8 0.1 1.0 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA PF00004.29 EWM23405.1 - 0.015 15.7 0.0 0.019 15.4 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EWM23405.1 - 0.078 13.2 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EWM23405.1 - 0.085 13.4 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EWM23405.1 - 0.09 12.8 0.0 0.49 10.4 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Toprim PF01751.22 EWM23406.1 - 1.8e-21 76.3 0.0 2.8e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Toprim domain Topoisom_bac PF01131.20 EWM23406.1 - 2e-18 66.6 0.0 2.9e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 DNA topoisomerase Mucin PF01456.17 EWM23406.1 - 9 6.3 13.4 8.3 6.4 9.6 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein RRM_1 PF00076.22 EWM23407.1 - 4.9e-21 74.3 0.0 1.6e-10 40.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EWM23407.1 - 5e-05 22.9 0.0 0.14 11.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 EWM23407.1 - 0.13 12.1 0.0 8.1 6.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) TBCC PF07986.12 EWM23408.1 - 9e-20 70.6 0.0 1.3e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 EWM23408.1 - 0.058 13.0 0.0 0.091 12.4 0.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal YjgF_endoribonc PF14588.6 EWM23409.1 - 3.4e-31 108.4 0.1 3.7e-31 108.3 0.1 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 EWM23409.1 - 1.8e-18 66.7 0.0 2.9e-18 66.0 0.0 1.3 1 1 0 1 1 1 1 Endoribonuclease L-PSP NAGPA PF09992.9 EWM23409.1 - 0.017 15.4 0.0 0.02 15.1 0.0 1.1 1 0 0 1 1 1 0 Phosphodiester glycosidase MazG PF03819.17 EWM23409.1 - 0.083 13.1 0.1 0.26 11.5 0.1 1.7 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain Topoisom_bac PF01131.20 EWM23410.1 - 1e-40 140.1 0.0 1.3e-40 139.7 0.0 1.0 1 0 0 1 1 1 1 DNA topoisomerase KH_1 PF00013.29 EWM23411.1 - 1.8e-27 95.0 1.8 6.7e-13 48.3 0.1 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EWM23411.1 - 0.07 13.0 2.5 7.4 6.5 0.1 2.7 3 0 0 3 3 3 0 KH domain KH_4 PF13083.6 EWM23411.1 - 0.1 12.5 0.4 56 3.7 0.0 3.3 3 0 0 3 3 3 0 KH domain CBM26 PF16738.5 EWM23411.1 - 0.18 12.1 0.1 0.43 10.9 0.1 1.5 1 0 0 1 1 1 0 Starch-binding module 26 Peptidase_A22B PF04258.13 EWM23412.1 - 5.1e-63 213.2 5.9 7.5e-63 212.7 5.9 1.1 1 0 0 1 1 1 1 Signal peptide peptidase PA PF02225.22 EWM23412.1 - 0.0051 16.8 0.0 0.2 11.7 0.0 2.6 2 0 0 2 2 2 1 PA domain Tox-HNH-HHH PF15637.6 EWM23412.1 - 0.09 12.9 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif CP12 PF02672.15 EWM23412.1 - 0.2 12.4 0.4 0.38 11.5 0.4 1.4 1 0 0 1 1 1 0 CP12 domain Presenilin PF01080.17 EWM23412.1 - 0.61 8.8 5.2 6.4 5.4 2.9 2.2 2 0 0 2 2 2 0 Presenilin RAP PF08373.10 EWM23413.1 - 0.019 15.1 0.0 0.039 14.0 0.0 1.5 1 0 0 1 1 1 0 RAP domain ADP_ribosyl_GH PF03747.14 EWM23414.1 - 1.3e-32 113.7 0.9 1.6e-32 113.4 0.9 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Suf PF05843.14 EWM23415.1 - 4.4e-29 102.4 0.3 2.3e-24 86.9 0.0 4.2 5 0 0 5 5 5 3 Suppressor of forked protein (Suf) HrpJ PF07201.11 EWM23415.1 - 2.5 8.4 4.9 2.5 8.4 0.2 3.3 4 0 0 4 4 4 0 HrpJ-like domain ACOX PF01756.19 EWM23417.1 - 6.1e-36 123.7 0.0 1.5e-35 122.4 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 EWM23417.1 - 3e-26 92.4 0.0 5.2e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 EWM23417.1 - 7.7e-09 35.6 0.0 1.4e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Toxin_5 PF05294.13 EWM23417.1 - 0.07 13.6 3.6 0.15 12.5 3.6 1.5 1 0 0 1 1 1 0 Scorpion short toxin Toprim_C_rpt PF13368.6 EWM23419.1 - 0.0068 16.4 0.0 0.018 15.0 0.0 1.7 1 1 0 1 1 1 1 Topoisomerase C-terminal repeat PGM_PMM_I PF02878.16 EWM23419.1 - 0.02 14.6 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Prot_ATP_OB_N PF17758.1 EWM23419.1 - 0.14 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain HMG_box_2 PF09011.10 EWM23421.1 - 5.5e-12 46.1 6.9 2e-07 31.5 0.4 2.7 2 1 0 2 2 2 2 HMG-box domain HMG_box PF00505.19 EWM23421.1 - 1.2e-11 44.8 3.1 4.2e-05 23.9 0.2 2.7 2 0 0 2 2 2 2 HMG (high mobility group) box Mso1_Sec1_bdg PF14475.6 EWM23423.1 - 0.13 11.8 0.2 0.24 11.0 0.2 1.4 1 0 0 1 1 1 0 Sec1-binding region of Mso1 Acetyltransf_16 PF05301.11 EWM23424.1 - 3.4e-39 134.4 0.0 4.6e-31 107.9 0.0 2.1 2 0 0 2 2 2 2 GNAT acetyltransferase, Mec-17 Acetyltransf_7 PF13508.7 EWM23424.1 - 0.076 13.4 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Tail_P2_I PF09684.10 EWM23424.1 - 0.17 11.8 0.1 3.1 7.7 0.1 2.1 2 0 0 2 2 2 0 Phage tail protein (Tail_P2_I) PH PF00169.29 EWM23426.1 - 0.017 15.6 0.0 0.02 15.4 0.0 1.1 1 0 0 1 1 1 0 PH domain PH_8 PF15409.6 EWM23426.1 - 0.089 13.1 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain RUN PF02759.19 EWM23426.1 - 0.18 11.7 0.0 0.2 11.6 0.0 1.1 1 0 0 1 1 1 0 RUN domain HECT PF00632.25 EWM23431.1 - 8.1e-57 193.0 0.0 1.3e-56 192.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 EWM23431.1 - 3.5e-13 49.7 0.0 9.1e-13 48.4 0.0 1.7 2 0 0 2 2 2 1 SPRY domain Vps62 PF06101.11 EWM23431.1 - 8.3e-06 24.4 0.0 0.0011 17.4 0.0 2.1 1 1 1 2 2 2 2 Vacuolar protein sorting-associated protein 62 Glyoxalase PF00903.25 EWM23432.1 - 1.6e-06 28.4 0.0 3.2e-06 27.3 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EWM23432.1 - 0.0015 19.3 0.0 0.0026 18.5 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 EWM23432.1 - 0.056 13.7 0.0 0.087 13.1 0.0 1.6 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Kelch_4 PF13418.6 EWM23434.1 - 5.3e-19 68.0 4.4 3.3e-07 30.2 0.2 3.7 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_3 PF13415.6 EWM23434.1 - 4.9e-17 61.8 4.4 2.7e-06 27.5 0.1 4.4 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 EWM23434.1 - 3.9e-16 58.4 13.1 1.8e-11 43.4 0.9 3.9 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 EWM23434.1 - 6.9e-12 44.8 12.9 1e-07 31.6 0.6 3.9 3 1 0 3 3 3 3 Kelch motif Kelch_5 PF13854.6 EWM23434.1 - 1e-10 41.3 9.3 5.1e-07 29.5 0.8 3.4 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 EWM23434.1 - 2.2e-10 40.4 9.8 1.2e-05 25.4 0.5 3.9 2 1 1 3 3 3 3 Kelch motif YjgF_endoribonc PF14588.6 EWM23442.1 - 2e-28 99.4 0.0 2.5e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 EWM23442.1 - 2.7e-16 59.7 0.0 4.4e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Endoribonuclease L-PSP 2-oxoacid_dh PF00198.23 EWM23444.1 - 4e-61 206.4 0.0 6.9e-61 205.7 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EWM23444.1 - 5.5e-58 192.7 18.2 4.7e-20 71.2 0.9 3.6 3 0 0 3 3 3 3 Biotin-requiring enzyme E3_binding PF02817.17 EWM23444.1 - 4.6e-22 78.1 4.1 5.2e-12 45.9 0.1 2.7 2 0 0 2 2 2 2 e3 binding domain Biotin_lipoyl_2 PF13533.6 EWM23444.1 - 1.6e-16 59.8 1.3 0.0002 21.1 0.0 4.5 3 1 1 4 4 4 3 Biotin-lipoyl like PYNP_C PF07831.13 EWM23444.1 - 9.6e-08 31.6 1.9 0.91 9.2 0.1 4.6 4 0 0 4 4 4 3 Pyrimidine nucleoside phosphorylase C-terminal domain HlyD_3 PF13437.6 EWM23444.1 - 3.1e-05 24.6 8.7 1 10.1 0.2 4.8 3 2 2 5 5 5 3 HlyD family secretion protein DUF2118 PF09891.9 EWM23444.1 - 3.4e-05 23.8 1.9 1.2 9.1 0.1 4.1 3 1 1 4 4 4 2 Uncharacterized protein conserved in archaea (DUF2118) PASTA PF03793.19 EWM23444.1 - 8.5e-05 22.3 2.7 2.6 8.0 0.1 3.7 3 0 0 3 3 3 2 PASTA domain HlyD_D23 PF16576.5 EWM23444.1 - 0.00015 21.1 1.9 2.1 7.5 0.1 3.4 2 1 1 3 3 3 3 Barrel-sandwich domain of CusB or HlyD membrane-fusion PTS_EIIA_1 PF00358.20 EWM23444.1 - 0.00019 21.2 1.0 2.8 7.7 0.0 3.7 3 0 0 3 3 3 2 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 RnfC_N PF13375.6 EWM23444.1 - 0.0004 20.3 5.8 0.076 13.0 0.1 4.1 2 1 2 4 4 4 1 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 EWM23444.1 - 0.00094 19.1 8.4 1.2 9.0 0.3 3.4 3 0 0 3 3 3 3 Glycine cleavage H-protein QRPTase_N PF02749.16 EWM23444.1 - 0.0099 15.9 3.6 26 5.0 0.0 4.6 5 0 0 5 5 4 0 Quinolinate phosphoribosyl transferase, N-terminal domain NfeD PF01957.18 EWM23444.1 - 0.11 12.9 11.6 4 7.9 0.1 4.1 4 0 0 4 4 3 0 NfeD-like C-terminal, partner-binding Peptidase_M23 PF01551.22 EWM23444.1 - 0.22 11.8 4.8 16 5.8 0.0 4.1 4 0 0 4 4 4 0 Peptidase family M23 NQRA PF05896.11 EWM23444.1 - 0.35 10.3 6.6 5.1 6.5 0.2 3.1 2 1 0 3 3 3 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) HlyD_2 PF12700.7 EWM23444.1 - 0.49 9.1 1.1 23 3.6 0.1 2.6 3 0 0 3 3 3 0 HlyD family secretion protein Fungus-induced PF10917.8 EWM23445.1 - 0.0051 17.1 0.2 0.009 16.3 0.2 1.3 1 0 0 1 1 1 1 Fungus-induced protein DUF2724 PF10893.8 EWM23445.1 - 0.022 14.6 0.3 0.04 13.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2724) Myb_DNA-binding PF00249.31 EWM23448.1 - 2.9e-28 97.8 5.8 4.4e-16 58.8 0.9 4.2 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EWM23448.1 - 3.3e-23 81.7 1.3 3.1e-18 65.8 0.1 3.2 2 1 1 3 3 3 2 Myb-like DNA-binding domain POM121 PF15229.6 EWM23448.1 - 0.0097 15.6 2.6 0.015 15.0 2.6 1.2 1 0 0 1 1 1 1 POM121 family TFIIF_alpha PF05793.12 EWM23448.1 - 0.2 10.2 13.1 0.25 9.9 13.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SLIDE PF09111.10 EWM23448.1 - 0.23 11.5 3.0 8.7 6.4 0.0 2.8 2 2 2 4 4 4 0 SLIDE Myb_DNA-bind_4 PF13837.6 EWM23448.1 - 0.24 11.8 8.6 3.7 8.0 1.3 3.3 3 1 1 4 4 4 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EWM23448.1 - 0.4 10.6 0.0 0.4 10.6 0.0 3.1 2 2 2 4 4 4 0 Myb DNA-binding like Myc_N PF01056.18 EWM23448.1 - 0.59 10.0 4.8 0.73 9.7 4.8 1.2 1 0 0 1 1 1 0 Myc amino-terminal region CDC45 PF02724.14 EWM23448.1 - 0.68 8.2 11.2 0.77 8.0 11.2 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 EWM23448.1 - 2.8 7.7 7.2 4 7.2 7.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RRN3 PF05327.11 EWM23448.1 - 5.9 5.3 5.8 6.9 5.1 5.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ILVD_EDD PF00920.21 EWM23449.1 - 4.9e-69 233.3 0.0 5.7e-69 233.1 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family Aldedh PF00171.22 EWM23451.1 - 3.7e-24 85.1 0.0 4.4e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF202 PF02656.15 EWM23453.1 - 9.4e-16 58.0 3.0 2.5e-15 56.7 3.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Clc-like PF07062.12 EWM23453.1 - 0.022 14.2 0.2 0.032 13.7 0.2 1.1 1 0 0 1 1 1 0 Clc-like MscS_TM PF12794.7 EWM23453.1 - 0.079 11.8 1.3 0.095 11.5 1.3 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF4199 PF13858.6 EWM23453.1 - 0.12 12.8 2.1 0.22 11.9 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Hydrolase PF00702.26 EWM23454.1 - 2.1e-17 64.1 0.3 2.8e-17 63.7 0.3 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EWM23454.1 - 7.4e-05 22.6 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EWM23454.1 - 0.12 12.8 0.1 0.36 11.2 0.1 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EWM23455.1 - 4.7e-28 98.9 1.0 7e-28 98.3 1.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EWM23455.1 - 1.9e-05 24.6 0.1 0.00023 21.0 0.0 2.0 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EWM23455.1 - 5.9e-05 23.6 0.2 0.00016 22.1 0.2 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EWM23455.1 - 0.0064 16.6 0.0 0.042 14.0 0.0 2.2 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase SfsA PF03749.13 EWM23455.1 - 0.18 11.7 0.0 0.38 10.6 0.0 1.4 1 0 0 1 1 1 0 Sugar fermentation stimulation protein RE domain FG-GAP PF01839.23 EWM23456.1 - 3.7e-31 106.9 35.9 8.3e-07 29.0 0.3 6.5 6 0 0 6 6 6 5 FG-GAP repeat VCBS PF13517.6 EWM23456.1 - 1.3e-16 60.9 23.7 2.1e-07 31.4 0.9 5.8 5 1 1 6 6 6 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.6 EWM23456.1 - 0.018 15.3 21.8 0.31 11.3 1.0 6.5 6 1 0 6 6 6 0 FG-GAP repeat E1-E2_ATPase PF00122.20 EWM23457.1 - 1.4e-11 44.2 0.0 1.5e-11 44.1 0.0 1.0 1 0 0 1 1 1 1 E1-E2 ATPase DUF3752 PF12572.8 EWM23459.1 - 1.4e-06 28.9 8.7 1.7e-06 28.6 8.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) Complex1_30kDa PF00329.19 EWM23460.1 - 8.7e-06 26.4 0.0 1e-05 26.1 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit DUF4148 PF13663.6 EWM23463.1 - 0.043 14.0 0.7 0.043 14.0 0.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4148) Sec15 PF04091.12 EWM23463.1 - 0.071 12.5 0.0 0.094 12.1 0.0 1.1 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like Lsr2 PF11774.8 EWM23463.1 - 0.091 12.9 0.6 0.12 12.5 0.6 1.2 1 0 0 1 1 1 0 Lsr2 Auxin_repressed PF05564.12 EWM23464.1 - 0.034 14.8 1.4 0.062 14.0 1.4 1.4 1 0 0 1 1 1 0 Dormancy/auxin associated protein FliD_C PF07195.12 EWM23467.1 - 0.014 14.9 0.6 0.017 14.6 0.6 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus CLZ PF16526.5 EWM23467.1 - 0.034 14.5 3.0 0.059 13.7 3.0 1.5 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fzo_mitofusin PF04799.13 EWM23467.1 - 0.037 13.6 0.9 0.053 13.1 0.9 1.3 1 0 0 1 1 1 0 fzo-like conserved region BCAS2 PF05700.11 EWM23467.1 - 0.039 13.6 5.1 0.06 13.0 5.1 1.3 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) HAUS6_N PF14661.6 EWM23467.1 - 0.059 12.9 2.3 0.074 12.6 2.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Nup54 PF13874.6 EWM23467.1 - 0.069 13.3 3.7 0.096 12.8 3.7 1.1 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 FlxA PF14282.6 EWM23467.1 - 0.1 12.6 5.0 0.15 12.0 5.0 1.2 1 0 0 1 1 1 0 FlxA-like protein WXG100 PF06013.12 EWM23467.1 - 0.33 11.2 4.0 0.27 11.5 0.4 2.2 1 1 2 3 3 3 0 Proteins of 100 residues with WXG DUF5446 PF17522.2 EWM23467.1 - 1.9 8.7 4.8 1.9 8.7 0.1 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5446) AKAP2_C PF15304.6 EWM23468.1 - 0.0028 17.0 0.1 0.0039 16.5 0.1 1.2 1 0 0 1 1 1 1 A-kinase anchor protein 2 C-terminus EcoEI_R_C PF08463.10 EWM23468.1 - 0.017 15.2 0.0 0.038 14.1 0.0 1.5 1 0 0 1 1 1 0 EcoEI R protein C-terminal RD3 PF14473.6 EWM23468.1 - 0.034 14.0 0.1 0.058 13.2 0.1 1.4 1 0 0 1 1 1 0 RD3 protein Slx4 PF09494.10 EWM23468.1 - 0.065 13.2 0.1 0.35 10.9 0.1 2.2 2 0 0 2 2 2 0 Slx4 endonuclease DUF1858 PF08984.11 EWM23468.1 - 0.09 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1858) GlnD_UR_UTase PF08335.11 EWM23468.1 - 0.11 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 GlnD PII-uridylyltransferase ScdA_N PF04405.14 EWM23468.1 - 0.2 11.3 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown function (DUF542) HrpJ PF07201.11 EWM23468.1 - 1.4 9.2 4.9 0.76 10.1 2.0 1.8 2 0 0 2 2 2 0 HrpJ-like domain CHD5 PF04420.14 EWM23469.1 - 0.14 12.0 0.4 0.29 11.0 0.4 1.6 1 0 0 1 1 1 0 CHD5-like protein Methyltransf_25 PF13649.6 EWM23472.1 - 4.6e-13 49.7 0.0 8.7e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM23472.1 - 6.1e-11 42.8 0.0 1e-10 42.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EWM23472.1 - 1e-08 35.8 0.0 1.8e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM23472.1 - 4.8e-08 32.9 0.0 8.1e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EWM23472.1 - 6.6e-06 26.1 0.0 9.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EWM23472.1 - 6.7e-05 22.4 0.0 0.00051 19.5 0.0 2.0 2 0 0 2 2 2 1 Tellurite resistance protein TehB MTS PF05175.14 EWM23472.1 - 0.0012 18.4 0.1 0.35 10.4 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase small domain FtsJ PF01728.19 EWM23472.1 - 0.012 15.8 0.0 0.017 15.3 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase NodS PF05401.11 EWM23472.1 - 0.038 13.6 0.0 0.2 11.3 0.0 2.1 2 1 0 2 2 2 0 Nodulation protein S (NodS) Methyltransf_24 PF13578.6 EWM23472.1 - 0.068 14.2 0.0 0.13 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EWM23472.1 - 0.075 12.4 0.1 0.26 10.6 0.1 1.7 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 EWM23472.1 - 0.15 11.8 0.0 0.45 10.2 0.0 1.7 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF5559 PF17714.1 EWM23475.1 - 0.0052 16.7 2.0 0.008 16.1 2.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5559) DUF2076 PF09849.9 EWM23475.1 - 0.0075 16.3 6.4 0.013 15.6 6.4 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Zn_clus PF00172.18 EWM23477.1 - 5.7e-05 23.2 9.8 0.00012 22.1 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zip PF02535.22 EWM23477.1 - 0.059 12.6 0.4 0.11 11.7 0.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Roughex PF06020.11 EWM23477.1 - 0.27 10.3 6.1 0.64 9.1 6.1 1.6 1 0 0 1 1 1 0 Drosophila roughex protein D123 PF07065.14 EWM23478.1 - 1.2e-63 215.1 0.0 1.3e-52 178.9 0.0 2.1 2 0 0 2 2 2 2 D123 IML1 PF12257.8 EWM23479.1 - 4.4e-81 272.1 0.0 2.4e-39 135.2 0.0 2.3 2 0 0 2 2 2 2 Vacuolar membrane-associated protein Iml1 IML1 PF12257.8 EWM23480.1 - 1.4e-69 234.4 0.0 2.4e-39 135.2 0.0 2.4 2 0 0 2 2 2 2 Vacuolar membrane-associated protein Iml1 EPTP PF03736.17 EWM23482.1 - 1.6e-08 34.4 0.1 3.3 7.8 0.0 5.4 5 0 0 5 5 5 3 EPTP domain RuBisCO_large_N PF02788.16 EWM23482.1 - 9.7 6.4 7.4 5.2 7.3 0.4 3.1 2 1 1 3 3 3 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain PT PF04886.12 EWM23483.1 - 9e-16 57.1 182.7 6.3e-07 28.8 16.0 7.5 2 1 3 5 5 5 4 PT repeat HSP20 PF00011.21 EWM23485.1 - 8.1e-08 32.4 0.0 2e-05 24.6 0.0 2.6 3 0 0 3 3 3 2 Hsp20/alpha crystallin family Peptidase_S49_N PF08496.10 EWM23485.1 - 1.1 9.3 3.9 1.8 8.6 3.9 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4407 PF14362.6 EWM23485.1 - 1.4 8.2 3.7 1.8 7.8 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) 2OG-FeII_Oxy_3 PF13640.6 EWM23486.1 - 0.011 16.6 0.0 0.026 15.4 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 EWM23486.1 - 0.014 15.8 0.0 0.077 13.4 0.0 2.1 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase His_Phos_2 PF00328.22 EWM23488.1 - 4.2e-10 39.5 0.0 7.2e-09 35.5 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF3463 PF11946.8 EWM23489.1 - 0.1 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3463) DUF5310 PF17237.2 EWM23490.1 - 0.0087 15.9 0.4 0.017 15.0 0.4 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5310) Carboxyl_trans PF01039.22 EWM23491.1 - 1.6e-143 479.0 0.0 2e-143 478.6 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 EWM23491.1 - 9e-05 22.1 0.1 0.038 13.5 0.0 2.2 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) H_lectin PF09458.10 EWM23492.1 - 0.1 12.8 0.4 1 9.6 0.1 2.1 2 0 0 2 2 2 0 H-type lectin domain Spore_III_AB PF09548.10 EWM23494.1 - 0.024 14.8 0.0 0.052 13.7 0.0 1.6 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Phe_tRNA-synt_N PF02912.18 EWM23494.1 - 0.07 13.1 0.3 0.16 11.9 0.3 1.5 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain TFIIF_beta PF02270.15 EWM23495.1 - 3.2e-14 52.8 0.0 4.8e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain Myotub-related PF06602.14 EWM23497.1 - 1.5e-78 264.2 0.0 1.8e-78 263.9 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 EWM23497.1 - 0.014 15.3 0.1 0.02 14.8 0.1 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.27 EWM23497.1 - 0.028 14.0 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.20 EWM23497.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain CAP PF00188.26 EWM23498.1 - 6.3e-05 23.8 0.5 0.0002 22.2 0.5 1.8 1 0 0 1 1 1 1 Cysteine-rich secretory protein family zf-C3H1 PF10650.9 EWM23498.1 - 0.85 9.4 3.8 1.7 8.5 0.6 2.5 2 0 0 2 2 2 0 Putative zinc-finger domain PH PF00169.29 EWM23501.1 - 0.00012 22.6 0.0 0.00017 22.0 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EWM23501.1 - 0.027 14.9 0.0 0.04 14.4 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain Beta-lactamase PF00144.24 EWM23503.1 - 0.013 14.8 0.0 0.013 14.8 0.0 1.0 1 0 0 1 1 1 0 Beta-lactamase Beta-lactamase PF00144.24 EWM23504.1 - 1e-22 80.9 0.0 1.2e-22 80.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3618 PF12277.8 EWM23506.1 - 0.039 14.2 1.3 3.7 7.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) DprA_WH PF17782.1 EWM23506.1 - 0.048 13.8 1.4 0.2 11.8 0.2 2.1 1 1 1 2 2 2 0 DprA winged helix domain TFIIE_beta PF02186.15 EWM23506.1 - 0.15 12.4 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 TFIIE beta subunit core domain NAD_kinase PF01513.21 EWM23511.1 - 8.3e-58 195.9 0.0 1.2e-57 195.4 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EWM23511.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Spec3 PF15795.5 EWM23513.1 - 2.2e-07 31.3 11.2 0.00022 21.7 6.4 2.1 1 1 1 2 2 2 2 Ectodermal ciliogenesis protein MBOAT PF03062.19 EWM23514.1 - 4e-22 79.0 8.8 4.9e-22 78.8 8.8 1.0 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EWM23514.1 - 2e-05 24.8 3.7 3.8e-05 23.9 3.7 1.4 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family ACBP PF00887.19 EWM23515.1 - 1.3e-17 63.7 0.1 5.1e-17 61.9 0.0 1.8 2 0 0 2 2 2 1 Acyl CoA binding protein Peptidase_S10 PF00450.22 EWM23516.1 - 0.003 17.0 0.0 0.0034 16.9 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.7 EWM23516.1 - 0.045 14.4 0.0 0.045 14.4 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EWM23516.1 - 0.12 11.9 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold ClpS PF02617.17 EWM23517.1 - 1.2e-05 25.0 0.0 1.6e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS ExbD PF02472.16 EWM23517.1 - 0.0058 16.8 0.0 0.013 15.7 0.0 1.6 1 1 0 1 1 1 1 Biopolymer transport protein ExbD/TolR MerB PF03243.15 EWM23517.1 - 0.18 12.0 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 Alkylmercury lyase Abhydrolase_1 PF00561.20 EWM23518.1 - 4.3e-06 26.6 0.0 6.2e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EWM23518.1 - 0.004 17.8 1.9 0.006 17.2 0.3 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydro_lipase PF04083.16 EWM23518.1 - 0.025 14.2 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region MFS_1 PF07690.16 EWM23520.1 - 1.1e-20 73.9 24.5 1.3e-20 73.6 24.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EWM23520.1 - 0.00027 19.9 2.0 0.00027 19.9 2.0 2.1 1 1 1 2 2 2 1 MFS_1 like family LacY_symp PF01306.19 EWM23520.1 - 0.006 15.4 6.3 0.5 9.1 0.1 2.0 2 0 0 2 2 2 2 LacY proton/sugar symporter MFS_3 PF05977.13 EWM23520.1 - 0.011 14.1 10.4 0.013 13.9 10.4 1.1 1 0 0 1 1 1 0 Transmembrane secretion effector Sugar_tr PF00083.24 EWM23520.1 - 0.045 12.6 12.4 0.022 13.6 4.1 2.3 1 1 1 2 2 2 0 Sugar (and other) transporter OppC_N PF12911.7 EWM23520.1 - 1.6 8.8 5.1 6.8 6.7 5.1 2.2 1 1 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C HpcH_HpaI PF03328.14 EWM23523.1 - 1.2e-12 47.4 0.0 1.6e-12 47.0 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family His_Phos_1 PF00300.22 EWM23524.1 - 1.4e-05 24.9 0.0 1.5e-05 24.8 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) POM121 PF15229.6 EWM23527.1 - 0.22 11.1 3.1 2.6 7.6 0.6 2.1 2 0 0 2 2 2 0 POM121 family DUF2070 PF09843.9 EWM23528.1 - 5.6 5.1 8.0 5.5 5.2 8.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DPM3 PF08285.11 EWM23529.1 - 6e-22 77.6 0.0 8.5e-22 77.2 0.0 1.2 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Adenylsucc_synt PF00709.21 EWM23530.1 - 4.4e-13 49.0 0.1 6e-13 48.5 0.1 1.1 1 0 0 1 1 1 1 Adenylosuccinate synthetase HAD_SAK_2 PF18143.1 EWM23530.1 - 0.1 12.9 0.1 0.13 12.6 0.1 1.2 1 0 0 1 1 1 0 HAD domain in Swiss Army Knife RNA repair proteins Hyccin PF09790.9 EWM23531.1 - 0.03 13.4 1.2 0.039 13.1 1.2 1.1 1 0 0 1 1 1 0 Hyccin Thioredoxin PF00085.20 EWM23532.1 - 1.9e-20 72.8 0.0 2.7e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 EWM23532.1 - 4.8e-05 23.5 0.0 0.00012 22.2 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EWM23532.1 - 0.00026 21.4 0.1 0.0012 19.3 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 EWM23532.1 - 0.00093 19.1 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 EWM23532.1 - 0.0011 19.2 0.0 0.015 15.6 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 EWM23532.1 - 0.006 16.3 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 EWM23532.1 - 0.0067 16.1 0.0 0.0095 15.7 0.0 1.4 1 1 0 1 1 1 1 Redoxin OST3_OST6 PF04756.13 EWM23532.1 - 0.015 14.6 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family PA PF02225.22 EWM23533.1 - 4.4e-05 23.4 0.0 0.00027 20.9 0.0 2.2 2 0 0 2 2 2 1 PA domain Mpp10 PF04006.12 EWM23533.1 - 0.01 14.3 20.8 0.013 13.9 20.8 1.1 1 0 0 1 1 1 0 Mpp10 protein CobT PF06213.12 EWM23533.1 - 0.07 12.5 26.6 0.11 11.9 26.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BUD22 PF09073.10 EWM23533.1 - 0.18 11.1 23.6 0.28 10.5 23.6 1.2 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 EWM23533.1 - 0.34 9.0 37.3 0.45 8.6 37.3 1.0 1 0 0 1 1 1 0 DNA polymerase phi RR_TM4-6 PF06459.12 EWM23533.1 - 0.36 10.6 12.9 0.56 10.0 12.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.14 EWM23533.1 - 0.77 10.2 5.7 1.8 9.0 5.7 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 SDA1 PF05285.12 EWM23533.1 - 0.9 8.9 27.9 1.3 8.4 27.9 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EWM23533.1 - 1.5 6.9 30.2 1.9 6.6 30.2 1.0 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 EWM23533.1 - 1.6 7.5 8.6 2 7.1 8.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein U1snRNP70_N PF12220.8 EWM23533.1 - 1.9 9.2 7.8 3.9 8.2 7.8 1.5 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal PPP4R2 PF09184.11 EWM23533.1 - 2.9 7.4 25.0 4.4 6.8 25.0 1.2 1 0 0 1 1 1 0 PPP4R2 Paf1 PF03985.13 EWM23533.1 - 5.8 5.8 23.7 8.1 5.3 23.7 1.1 1 0 0 1 1 1 0 Paf1 Presenilin PF01080.17 EWM23533.1 - 8.5 5.0 7.6 12 4.6 7.6 1.1 1 0 0 1 1 1 0 Presenilin SpoIIP PF07454.11 EWM23533.1 - 9.3 5.6 9.9 13 5.1 9.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) YabA PF06156.13 EWM23536.1 - 0.0077 16.8 0.3 0.011 16.3 0.3 1.2 1 0 0 1 1 1 1 Initiation control protein YabA DUF3584 PF12128.8 EWM23536.1 - 0.021 12.4 0.3 0.026 12.1 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Prefoldin_2 PF01920.20 EWM23536.1 - 0.29 11.1 4.4 1.9 8.5 0.1 2.1 1 1 1 2 2 2 0 Prefoldin subunit Atg14 PF10186.9 EWM23536.1 - 0.3 10.1 1.3 0.39 9.7 1.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FlaC_arch PF05377.11 EWM23536.1 - 0.33 11.4 2.2 4.5 7.7 2.0 2.2 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 EWM23536.1 - 0.33 10.7 2.6 3.6 7.4 2.8 2.1 1 1 1 2 2 2 0 Septum formation initiator ZapB PF06005.12 EWM23536.1 - 0.7 10.4 4.9 2 8.9 4.9 1.6 1 1 0 1 1 1 0 Cell division protein ZapB RecA PF00154.21 EWM23537.1 - 6.1e-34 117.7 0.0 4.6e-33 114.8 0.0 1.9 2 0 0 2 2 2 1 recA bacterial DNA recombination protein ATPase PF06745.13 EWM23537.1 - 0.0093 15.3 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 KaiC Glyco_hydro_47 PF01532.20 EWM23538.1 - 3.4e-28 98.7 0.0 4.8e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Apt1 PF10351.9 EWM23538.1 - 0.094 11.6 5.2 0.1 11.4 5.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 EWM23538.1 - 0.13 12.1 6.7 0.14 12.0 6.7 1.1 1 0 0 1 1 1 0 SPX domain DUF4614 PF15391.6 EWM23538.1 - 1.5 8.8 15.5 2.1 8.3 15.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) ATP-grasp_4 PF13535.6 EWM23541.1 - 4.4e-08 32.9 0.0 7.1e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 EWM23541.1 - 0.00061 19.6 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_Ter PF15632.6 EWM23541.1 - 0.0024 17.6 0.0 0.004 16.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 EWM23541.1 - 0.016 15.3 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain BES1_N PF05687.13 EWM23541.1 - 8.2 6.8 7.6 23 5.3 7.6 1.7 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal RHS PF03527.14 EWM23542.1 - 0.15 11.8 0.6 0.27 11.0 0.6 1.4 1 0 0 1 1 1 0 RHS protein RHS PF03527.14 EWM23543.1 - 0.29 10.9 3.2 0.31 10.8 0.6 2.1 2 0 0 2 2 2 0 RHS protein CSD PF00313.22 EWM23545.1 - 3.2e-23 81.4 0.4 3.9e-23 81.1 0.4 1.1 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 EWM23545.1 - 4e-06 26.4 0.1 6.3e-06 25.8 0.1 1.5 1 1 0 1 1 1 1 Ribonuclease B OB domain Rho_RNA_bind PF07497.12 EWM23545.1 - 0.0016 18.2 0.1 0.0025 17.7 0.1 1.4 1 0 0 1 1 1 1 Rho termination factor, RNA-binding domain Fer2 PF00111.27 EWM23547.1 - 4.5e-09 36.2 0.5 6.8e-09 35.6 0.5 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF3371 PF11851.8 EWM23547.1 - 0.62 11.2 6.0 0.92 10.6 6.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) DnaJ_CXXCXGXG PF00684.19 EWM23548.1 - 0.002 18.4 14.9 0.0097 16.2 14.9 2.4 1 1 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EWM23548.1 - 0.038 13.9 13.9 0.24 11.4 4.6 3.0 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-rbx1 PF12678.7 EWM23548.1 - 0.27 11.6 3.8 2 8.8 0.6 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger domain zinc_ribbon_9 PF14369.6 EWM23548.1 - 2.9 8.2 8.5 7 7.0 0.1 3.6 3 1 0 3 3 3 0 zinc-ribbon A2L_zn_ribbon PF08792.10 EWM23548.1 - 8.2 6.3 11.0 54 3.7 4.2 3.3 2 1 1 3 3 3 0 A2L zinc ribbon domain Na_H_Exchanger PF00999.21 EWM23549.1 - 8.7e-53 179.5 43.1 1.4e-52 178.8 43.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family S4 PF01479.25 EWM23552.1 - 1.6e-12 46.9 0.0 4.8e-12 45.4 0.0 1.8 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 EWM23552.1 - 2.2e-11 44.5 0.7 3.1e-11 44.0 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain EKLF_TAD1 PF16832.5 EWM23552.1 - 0.28 11.1 1.3 2.1 8.3 0.1 2.5 3 0 0 3 3 3 0 Erythroid krueppel-like transcription factor, transactivation 1 Ribosomal_S4 PF00163.19 EWM23553.1 - 1.3e-11 45.2 0.6 1.6e-11 44.9 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 EWM23553.1 - 2.2e-08 33.7 0.0 7.4e-08 32.0 0.0 1.9 2 0 0 2 2 2 1 S4 domain Wyosine_form PF08608.12 EWM23554.1 - 2.2e-23 82.4 0.1 3.9e-23 81.6 0.1 1.4 1 0 0 1 1 1 1 Wyosine base formation Wyosine_form PF08608.12 EWM23555.1 - 2.8e-20 72.4 0.2 1.4e-13 51.0 0.0 2.5 2 0 0 2 2 2 2 Wyosine base formation LRR_6 PF13516.6 EWM23557.1 - 1.5e-32 108.8 4.3 0.023 14.7 0.0 12.6 13 0 0 13 13 13 8 Leucine Rich repeat LRR_4 PF12799.7 EWM23557.1 - 2.3e-16 59.6 0.0 0.5 10.9 0.0 8.4 8 2 1 9 9 9 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EWM23557.1 - 2.4e-09 36.4 0.0 36 5.5 0.0 9.3 12 0 0 12 12 12 1 Leucine Rich Repeat LRR_8 PF13855.6 EWM23557.1 - 2.9e-07 30.2 8.2 2 8.2 0.0 9.1 8 3 1 9 9 9 1 Leucine rich repeat UPF0262 PF06793.12 EWM23557.1 - 0.0087 16.2 0.1 1.7 8.8 0.0 2.8 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0262) PRIMA1 PF16101.5 EWM23558.1 - 0.5 10.4 5.3 0.94 9.5 5.3 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 WD40 PF00400.32 EWM23559.1 - 2.8e-06 27.9 0.3 0.00014 22.6 0.4 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat OPA3 PF07047.12 EWM23560.1 - 9e-29 99.8 0.2 9e-29 99.8 0.2 2.4 2 0 0 2 2 2 1 Optic atrophy 3 protein (OPA3) Ribosomal_60s PF00428.19 EWM23560.1 - 9.7 6.9 20.6 5.9 7.6 13.8 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Seipin PF06775.14 EWM23562.1 - 1.8e-45 155.5 0.9 2.6e-45 155.0 0.9 1.2 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) PDZ_6 PF17820.1 EWM23563.1 - 6e-09 35.6 0.3 0.0005 19.9 0.0 4.3 4 0 0 4 4 4 2 PDZ domain PDZ PF00595.24 EWM23563.1 - 7.7e-08 32.6 0.0 0.36 11.2 0.0 4.1 4 0 0 4 4 4 3 PDZ domain Mito_carr PF00153.27 EWM23564.1 - 2.7e-06 27.2 0.3 4.9e-05 23.2 0.1 2.3 2 1 0 2 2 2 1 Mitochondrial carrier protein SNARE_assoc PF09335.11 EWM23566.1 - 2.8e-18 66.5 9.6 6.8e-18 65.3 9.6 1.7 1 0 0 1 1 1 1 SNARE associated Golgi protein Colicin_V PF02674.16 EWM23566.1 - 0.055 13.5 13.2 1.4 8.9 0.1 2.2 2 0 0 2 2 2 0 Colicin V production protein cobW PF02492.19 EWM23567.1 - 3.5e-38 131.0 0.0 4.9e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EWM23567.1 - 2.9e-05 23.9 0.0 0.00084 19.2 0.0 2.6 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain AAA_24 PF13479.6 EWM23567.1 - 0.051 13.3 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EWM23567.1 - 0.059 13.8 0.1 0.17 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 EWM23567.1 - 0.074 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EWM23567.1 - 0.082 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EWM23567.1 - 0.15 12.5 0.0 0.26 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EWM23567.1 - 0.19 11.6 0.0 3.4 7.5 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase T2SSE PF00437.20 EWM23567.1 - 0.21 10.6 0.0 0.33 10.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein LRR_9 PF14580.6 EWM23568.1 - 2e-06 27.4 2.0 0.012 15.1 0.6 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 EWM23568.1 - 4.7e-06 26.3 6.5 5.1e-05 23.0 3.0 2.5 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 EWM23568.1 - 4.4e-05 23.8 7.7 0.0028 18.0 0.1 3.4 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) DUF3516 PF12029.8 EWM23568.1 - 0.037 13.1 0.0 0.077 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) LRR_6 PF13516.6 EWM23568.1 - 0.22 11.6 0.5 17 5.8 0.1 3.0 2 0 0 2 2 2 0 Leucine Rich repeat DUF4407 PF14362.6 EWM23569.1 - 0.015 14.7 2.3 0.022 14.1 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DEC-1_N PF04625.13 EWM23569.1 - 0.91 8.5 8.9 1.4 7.8 8.9 1.3 1 1 0 1 1 1 0 DEC-1 protein, N-terminal region CCDC-167 PF15188.6 EWM23569.1 - 3.7 7.9 6.0 9.9 6.6 6.0 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Ribosomal_S13_N PF08069.12 EWM23570.1 - 1e-29 102.3 0.2 1.9e-29 101.5 0.2 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 EWM23570.1 - 1.2e-10 41.4 1.7 2e-10 40.8 1.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 LINES_C PF14695.6 EWM23570.1 - 0.046 13.2 1.6 0.23 10.9 0.0 2.5 3 0 0 3 3 3 0 Lines C-terminus Ribosomal_L21e PF01157.18 EWM23571.1 - 3.5e-45 152.0 3.1 6.6e-45 151.1 2.2 1.7 2 0 0 2 2 2 1 Ribosomal protein L21e FAP PF07174.11 EWM23573.1 - 2 7.8 9.3 3.1 7.2 9.3 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) GalKase_gal_bdg PF10509.9 EWM23574.1 - 1e-20 73.0 0.1 1.5e-20 72.5 0.1 1.2 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 EWM23575.1 - 1.1e-06 28.9 0.0 1.6e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 GHMP kinases C terminal IPTL-CTERM PF18203.1 EWM23575.1 - 0.46 10.4 3.9 0.86 9.6 3.9 1.5 1 0 0 1 1 1 0 IPTL-CTERM motif La PF05383.17 EWM23576.1 - 0.00061 19.8 0.0 0.00096 19.2 0.0 1.3 1 0 0 1 1 1 1 La domain DNA_photolyase PF00875.18 EWM23577.1 - 3.4e-15 56.4 0.0 4.8e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 DNA photolyase DUF4451 PF14616.6 EWM23578.1 - 0.053 13.7 0.1 0.1 12.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4451) HlyIII PF03006.20 EWM23580.1 - 5e-13 49.3 21.0 6.6e-13 48.9 21.0 1.2 1 0 0 1 1 1 1 Haemolysin-III related Hum_adeno_E3A PF05393.11 EWM23580.1 - 3 7.9 5.3 5.7 7.0 0.4 2.5 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein PALP PF00291.25 EWM23581.1 - 1.6e-43 149.2 0.6 9.7e-34 117.1 0.3 2.2 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme DUF2052 PF09747.9 EWM23581.1 - 0.28 11.3 6.4 0.14 12.3 3.5 1.8 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Paf1 PF03985.13 EWM23581.1 - 0.38 9.7 7.9 0.64 9.0 7.9 1.3 1 0 0 1 1 1 0 Paf1 Bot1p PF12298.8 EWM23581.1 - 0.67 10.1 3.0 1.2 9.3 3.0 1.3 1 0 0 1 1 1 0 Eukaryotic mitochondrial regulator protein CUTL PF16557.5 EWM23582.1 - 0.031 14.4 0.1 0.095 12.9 0.1 1.8 1 0 0 1 1 1 0 CUT1-like DNA-binding domain of SATB Elf1 PF05129.13 EWM23583.1 - 9.2e-25 86.5 7.0 1.1e-24 86.3 7.0 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Prim_Zn_Ribbon PF08273.12 EWM23583.1 - 0.16 12.3 2.4 0.2 12.0 0.2 2.1 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase IBR PF01485.21 EWM23583.1 - 3.6 7.9 7.7 0.92 9.8 4.4 1.8 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Methyltransf_16 PF10294.9 EWM23585.1 - 6.1e-21 74.9 0.0 1.7e-20 73.5 0.0 1.6 1 1 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 EWM23585.1 - 0.0071 15.8 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EWM23585.1 - 0.18 11.3 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain MutS_I PF01624.20 EWM23586.1 - 1.6e-23 83.1 0.0 2.6e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 MutS domain I SR-25 PF10500.9 EWM23586.1 - 0.001 18.7 14.3 0.001 18.7 14.3 1.7 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DGF-1_C PF11040.8 EWM23586.1 - 0.035 14.1 0.0 0.035 14.1 0.0 3.1 2 1 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus PCO_ADO PF07847.12 EWM23588.1 - 1.9e-39 135.2 0.0 2.9e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 PCO_ADO DUF4228 PF14009.6 EWM23588.1 - 0.0025 18.3 1.1 2.5 8.4 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4228) SR-25 PF10500.9 EWM23588.1 - 0.0095 15.6 12.0 0.0095 15.6 12.0 2.4 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein FRG2 PF15315.6 EWM23588.1 - 0.16 12.2 9.5 0.31 11.2 9.5 1.4 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 DMSP_lyase PF16867.5 EWM23588.1 - 0.17 11.5 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase Nucleo_P87 PF07267.11 EWM23588.1 - 0.92 8.3 3.6 1.2 7.9 3.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF2039 PF10217.9 EWM23590.1 - 3.9e-30 104.0 8.2 5.6e-30 103.5 8.2 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) Paired_CXXCH_1 PF09699.10 EWM23590.1 - 0.014 15.2 0.5 0.014 15.2 0.5 3.0 2 1 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Ribosomal_S18 PF01084.20 EWM23590.1 - 0.092 13.0 0.2 8.3 6.7 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein S18 zinc-ribbons_6 PF07191.12 EWM23590.1 - 0.16 12.0 11.1 0.4 10.7 11.1 1.7 1 1 0 1 1 1 0 zinc-ribbons FYVE_2 PF02318.16 EWM23590.1 - 0.19 11.9 4.9 0.33 11.2 4.9 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Cript PF10235.9 EWM23590.1 - 0.23 12.1 12.1 0.11 13.1 8.4 2.0 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT Cytochrome_C7 PF14522.6 EWM23590.1 - 0.29 11.1 11.0 0.71 9.9 10.4 2.0 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c zf_C2HC_14 PF18574.1 EWM23590.1 - 7.1 6.5 9.5 4.5 7.1 0.2 3.4 4 0 0 4 4 4 0 C2HC Zing finger domain DUF2039 PF10217.9 EWM23591.1 - 4.3e-30 103.9 8.2 6.7e-30 103.3 8.2 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) Paired_CXXCH_1 PF09699.10 EWM23591.1 - 0.015 15.0 0.5 0.015 15.0 0.5 3.0 2 1 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Ribosomal_S18 PF01084.20 EWM23591.1 - 0.11 12.7 0.2 9.2 6.6 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein S18 zinc-ribbons_6 PF07191.12 EWM23591.1 - 0.16 12.0 11.1 0.46 10.5 11.0 1.8 1 1 0 1 1 1 0 zinc-ribbons Cript PF10235.9 EWM23591.1 - 0.21 12.2 12.1 0.86 10.2 12.0 2.0 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT FYVE_2 PF02318.16 EWM23591.1 - 0.22 11.8 4.9 0.38 11.0 4.9 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Cytochrome_C7 PF14522.6 EWM23591.1 - 0.31 11.1 11.0 0.62 10.1 10.0 2.1 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c DUF2039 PF10217.9 EWM23592.1 - 4.7e-30 103.8 8.2 6.8e-30 103.3 8.2 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) Paired_CXXCH_1 PF09699.10 EWM23592.1 - 0.015 15.0 0.5 0.015 15.0 0.5 3.1 2 1 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) PAS PF00989.25 EWM23592.1 - 0.045 13.8 0.0 0.097 12.7 0.0 1.5 1 0 0 1 1 1 0 PAS fold Ribosomal_S18 PF01084.20 EWM23592.1 - 0.11 12.7 0.2 9.3 6.6 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein S18 zinc-ribbons_6 PF07191.12 EWM23592.1 - 0.18 11.8 11.1 0.46 10.5 11.0 1.7 1 1 0 1 1 1 0 zinc-ribbons FYVE_2 PF02318.16 EWM23592.1 - 0.23 11.7 4.9 0.39 10.9 4.9 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Cript PF10235.9 EWM23592.1 - 0.23 12.0 12.2 0.95 10.1 12.2 2.0 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT Cytochrome_C7 PF14522.6 EWM23592.1 - 0.33 11.0 11.0 0.74 9.9 10.2 2.0 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c zf_C2HC_14 PF18574.1 EWM23592.1 - 9.3 6.1 9.5 5 7.0 0.2 3.4 4 0 0 4 4 4 0 C2HC Zing finger domain HMG_box PF00505.19 EWM23593.1 - 1.8e-14 53.9 1.9 1.8e-14 53.9 1.9 2.7 2 0 0 2 2 2 1 HMG (high mobility group) box CBFD_NFYB_HMF PF00808.23 EWM23593.1 - 2.3e-13 50.2 0.5 8.8e-13 48.3 0.2 2.2 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HMG_box_2 PF09011.10 EWM23593.1 - 1.3e-11 44.9 3.2 1.3e-11 44.9 3.2 2.5 3 0 0 3 3 3 1 HMG-box domain Histone PF00125.24 EWM23593.1 - 0.00013 22.3 0.3 0.00013 22.3 0.3 3.7 4 1 0 4 4 4 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EWM23593.1 - 0.00098 19.2 0.4 0.0027 17.8 0.1 1.9 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold Nop10p PF04135.12 EWM23594.1 - 2.4e-07 30.7 0.1 3.8e-07 30.1 0.1 1.3 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Cystatin PF00031.21 EWM23596.1 - 0.00012 22.3 0.0 0.00032 20.9 0.0 1.7 1 1 0 1 1 1 1 Cystatin domain SQAPI PF16845.5 EWM23596.1 - 0.0011 19.3 0.2 0.0035 17.7 0.2 1.8 1 1 0 1 1 1 1 Aspartic acid proteinase inhibitor Cyclin_N PF00134.23 EWM23597.1 - 1.3e-31 108.9 0.2 2.2e-31 108.2 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EWM23597.1 - 9.6e-05 22.5 0.9 0.00022 21.3 0.3 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain CDC45 PF02724.14 EWM23597.1 - 0.45 8.8 5.7 0.61 8.3 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Pex2_Pex12 PF04757.14 EWM23598.1 - 7.2e-14 51.9 0.5 7.3e-13 48.6 0.5 2.3 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 EWM23598.1 - 4e-09 36.2 13.6 7.4e-09 35.3 13.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EWM23598.1 - 6.3e-09 35.6 14.6 1.1e-08 34.8 14.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EWM23598.1 - 2.3e-08 34.2 13.8 3.8e-08 33.5 13.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EWM23598.1 - 1.3e-07 31.4 12.6 2.1e-07 30.7 12.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EWM23598.1 - 6.6e-07 29.1 14.4 1.1e-06 28.4 14.4 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EWM23598.1 - 2e-05 24.5 10.5 3.7e-05 23.6 10.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EWM23598.1 - 7.2e-05 23.0 10.5 0.00013 22.2 10.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EWM23598.1 - 8.2e-05 22.5 10.5 0.00021 21.2 10.4 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EWM23598.1 - 0.00047 20.2 12.9 0.00086 19.4 12.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 EWM23598.1 - 0.32 10.8 3.2 0.71 9.7 3.2 1.6 1 0 0 1 1 1 0 RING-like zinc finger PrmA PF06325.13 EWM23599.1 - 8.4e-11 41.8 1.8 1.1e-10 41.3 1.2 1.5 1 1 1 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EWM23599.1 - 1.4e-09 37.9 0.0 2.2e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM23599.1 - 1.3e-08 35.5 0.1 2.9e-08 34.3 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM23599.1 - 6.8e-08 33.1 0.1 1.6e-07 31.8 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EWM23599.1 - 2.3e-06 27.3 0.1 3.8e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 EWM23599.1 - 0.00018 20.9 0.1 0.00028 20.3 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EWM23599.1 - 0.00037 19.9 0.7 0.00037 19.9 0.7 1.7 1 1 1 2 2 2 1 Mycolic acid cyclopropane synthetase Met_10 PF02475.16 EWM23599.1 - 0.00064 19.5 0.2 0.0011 18.7 0.2 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.7 EWM23599.1 - 0.00084 19.3 0.1 0.0018 18.3 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EWM23599.1 - 0.0014 17.6 0.1 0.0021 17.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 EWM23599.1 - 0.0023 17.8 0.0 0.004 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EWM23599.1 - 0.006 16.7 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 EWM23599.1 - 0.013 15.3 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_24 PF13578.6 EWM23599.1 - 0.019 16.0 0.1 0.053 14.5 0.1 1.8 1 0 0 1 1 1 0 Methyltransferase domain OpuAC PF04069.12 EWM23599.1 - 0.032 13.8 0.1 0.055 13.0 0.1 1.4 1 0 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system PCMT PF01135.19 EWM23599.1 - 0.033 13.9 0.2 0.063 13.0 0.2 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 EWM23599.1 - 0.062 12.3 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FAD_binding_4 PF01565.23 EWM23600.1 - 3.9e-20 72.0 2.1 5.5e-20 71.5 2.1 1.2 1 0 0 1 1 1 1 FAD binding domain DSPc PF00782.20 EWM23603.1 - 2.3e-26 92.2 0.0 3.2e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EWM23603.1 - 0.026 14.1 0.0 0.044 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF3889 PF13028.6 EWM23603.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3889) DSPc PF00782.20 EWM23604.1 - 2.3e-26 92.2 0.0 3.2e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EWM23604.1 - 0.026 14.1 0.0 0.044 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF3889 PF13028.6 EWM23604.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3889) IBN_N PF03810.19 EWM23606.1 - 6.3e-07 29.2 0.0 9.7e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain PPI_Ypi1 PF07491.11 EWM23608.1 - 7.7e-24 83.3 2.6 1.7e-23 82.2 2.6 1.6 1 0 0 1 1 1 1 Protein phosphatase inhibitor PTPRCAP PF15713.5 EWM23608.1 - 5.6 7.3 12.7 0.97 9.7 8.6 1.7 1 1 1 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated DUF775 PF05603.12 EWM23609.1 - 3.3e-33 114.9 0.0 1.3e-31 109.7 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF775) zf-RING_2 PF13639.6 EWM23610.1 - 3.8e-11 43.1 7.9 6.4e-11 42.4 7.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EWM23610.1 - 5.6e-07 29.2 2.5 1.4e-06 27.9 2.5 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EWM23610.1 - 2.5e-06 27.2 7.0 4e-06 26.6 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EWM23610.1 - 4.9e-05 23.5 5.3 9.4e-05 22.6 5.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EWM23610.1 - 0.0048 16.7 5.3 0.0071 16.2 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EWM23610.1 - 0.0056 16.5 5.7 0.0085 15.9 5.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EWM23610.1 - 0.27 11.2 5.7 0.41 10.7 5.7 1.3 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 EWM23610.1 - 1.5 8.8 7.9 2.5 8.0 7.9 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Thaumatin PF00314.17 EWM23613.1 - 1.3e-07 31.5 2.0 1.7e-07 31.1 2.0 1.1 1 0 0 1 1 1 1 Thaumatin family PH PF00169.29 EWM23615.1 - 8.4e-08 32.7 0.0 1.2e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 PH domain Stb3 PF10330.9 EWM23615.1 - 0.062 13.3 0.2 0.12 12.4 0.2 1.4 1 0 0 1 1 1 0 Putative Sin3 binding protein BK_channel_a PF03493.18 EWM23619.1 - 1.3e-20 73.4 0.0 2.3e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 EWM23619.1 - 3.7e-12 46.0 8.2 3.7e-12 46.0 8.2 2.2 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 EWM23619.1 - 6.2e-09 35.4 17.5 1.7e-08 34.0 17.5 1.6 1 1 0 1 1 1 1 Ion transport protein Peptidase_A24 PF01478.18 EWM23619.1 - 0.34 11.3 4.2 0.62 10.5 2.5 2.3 2 0 0 2 2 2 0 Type IV leader peptidase family Complex1_LYR PF05347.15 EWM23620.1 - 2.1e-08 34.1 0.2 2.9e-08 33.6 0.2 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EWM23620.1 - 0.0013 19.4 0.6 0.0017 19.1 0.6 1.3 1 0 0 1 1 1 1 Complex1_LYR-like PseudoU_synth_1 PF01416.20 EWM23621.1 - 1.5e-26 93.0 0.0 8.1e-26 90.6 0.0 2.2 2 0 0 2 2 2 1 tRNA pseudouridine synthase NAD_binding_10 PF13460.6 EWM23622.1 - 2.5e-10 40.6 0.0 4.2e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EWM23622.1 - 3.9e-07 29.3 0.0 5.8e-06 25.5 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EWM23622.1 - 6.5e-06 25.8 0.1 1.4e-05 24.7 0.1 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EWM23622.1 - 4.7e-05 23.1 0.0 7.5e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 EWM23622.1 - 0.00086 18.5 0.1 0.15 11.1 0.1 2.7 2 1 0 2 2 2 2 RmlD substrate binding domain NAD_binding_4 PF07993.12 EWM23622.1 - 0.096 11.8 0.0 4.3 6.4 0.0 2.6 1 1 1 3 3 3 0 Male sterility protein Antimicrobial14 PF08109.11 EWM23622.1 - 0.11 12.6 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 Lactocin 705 family ACP_PD PF04336.12 EWM23623.1 - 0.51 10.8 2.8 0.64 10.5 0.2 2.5 3 0 0 3 3 3 0 Acyl carrier protein phosphodiesterase CwsA PF10814.8 EWM23624.1 - 0.016 15.4 0.1 0.035 14.3 0.1 1.6 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA COX4 PF02936.14 EWM23624.1 - 0.065 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV DUF2933 PF11666.8 EWM23625.1 - 0.36 10.9 1.6 0.64 10.1 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2933) Aldo_ket_red PF00248.21 EWM23626.1 - 1.1e-54 185.6 0.0 1.4e-54 185.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Endonuc-BsobI PF09194.10 EWM23626.1 - 0.042 13.0 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease BsobI DUF3446 PF11928.8 EWM23627.1 - 4.2 7.7 19.0 2 8.8 11.3 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain Methyltransf_11 PF08241.12 EWM23628.1 - 3.8e-11 43.5 0.0 8.9e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EWM23628.1 - 2.5e-08 33.9 0.0 4.9e-08 33.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM23628.1 - 2.9e-07 31.1 0.0 7.5e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM23628.1 - 3e-07 30.4 0.0 5.1e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EWM23628.1 - 5.6e-07 30.2 0.0 3.3e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EWM23628.1 - 1.7e-06 27.5 0.0 3.5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family KH_1 PF00013.29 EWM23629.1 - 4.5e-47 157.7 13.4 2.1e-15 56.3 0.4 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EWM23629.1 - 1.4e-16 60.1 3.9 7.3e-07 28.9 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EWM23629.1 - 1.6e-08 34.3 4.7 0.037 13.9 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 EWM23629.1 - 0.0002 21.4 5.1 2.2 8.4 0.0 3.3 3 0 0 3 3 3 3 NusA-like KH domain BMC PF00936.19 EWM23629.1 - 0.17 11.9 0.2 11 6.1 0.0 2.4 2 0 0 2 2 2 0 BMC domain Cullin PF00888.22 EWM23630.1 - 5.8e-64 216.8 0.0 2.8e-44 151.8 0.0 2.0 2 0 0 2 2 2 2 Cullin family DUF1995 PF09353.10 EWM23631.1 - 2.7e-22 79.8 0.0 5.2e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) PAP_fibrillin PF04755.12 EWM23631.1 - 0.002 18.1 0.0 0.36 10.7 0.0 2.4 1 1 0 1 1 1 1 PAP_fibrillin T3SS_needle_E PF08988.10 EWM23631.1 - 0.0086 16.2 0.5 0.8 9.9 0.4 2.7 2 0 0 2 2 2 1 Type III secretion system, cytoplasmic E component of needle TPR_14 PF13428.6 EWM23632.1 - 1.9 9.5 11.6 2.4 9.2 0.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat CRAL_TRIO PF00650.20 EWM23633.1 - 9.9e-30 103.4 0.0 1.3e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EWM23633.1 - 1e-10 41.9 0.0 2.2e-10 40.8 0.0 1.5 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain Pkinase PF00069.25 EWM23634.1 - 4.9e-72 242.5 0.0 5.9e-72 242.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM23634.1 - 1.2e-31 110.0 0.0 1.5e-31 109.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EWM23634.1 - 0.00034 20.0 0.0 0.0062 15.9 0.0 2.1 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 EWM23634.1 - 0.00055 19.9 0.0 0.004 17.1 0.0 1.9 1 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EWM23634.1 - 0.00055 19.0 0.0 0.0033 16.4 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EWM23634.1 - 0.03 13.7 0.0 0.058 12.7 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2760 PF10816.8 EWM23634.1 - 0.038 13.8 0.0 0.095 12.5 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2760) CGI-121 PF08617.10 EWM23636.1 - 4.7e-23 82.1 0.0 6.4e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Kinase binding protein CGI-121 HLH PF00010.26 EWM23637.1 - 4.2e-07 29.8 3.5 6.6e-07 29.2 3.5 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_3 PF08447.12 EWM23637.1 - 0.00051 20.3 0.0 0.00095 19.4 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.6 EWM23637.1 - 0.026 14.6 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 PAS domain PAS_8 PF13188.7 EWM23637.1 - 0.053 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 PAS domain PAS_9 PF13426.7 EWM23637.1 - 0.068 13.4 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 PAS domain 2-oxoacid_dh PF00198.23 EWM23638.1 - 1.4e-76 257.0 0.2 1.4e-76 257.0 0.2 1.5 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EWM23638.1 - 2.4e-19 68.9 2.7 4.4e-19 68.1 2.7 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EWM23638.1 - 0.079 12.8 4.8 2 8.3 0.8 2.6 1 1 1 2 2 2 0 Biotin-lipoyl like HlyD_3 PF13437.6 EWM23638.1 - 0.084 13.6 3.3 7 7.4 0.2 2.4 1 1 1 2 2 2 0 HlyD family secretion protein CCDC53 PF10152.9 EWM23638.1 - 0.094 13.1 1.2 0.15 12.5 1.2 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex TRM PF02005.16 EWM23640.1 - 9.4e-116 387.1 0.0 1.2e-115 386.8 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase PrmA PF06325.13 EWM23640.1 - 0.0056 16.1 0.1 0.013 14.9 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EWM23640.1 - 0.048 14.4 0.0 0.15 12.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 EWM23640.1 - 0.054 13.3 0.0 0.089 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CRT-like PF08627.10 EWM23641.1 - 3.6e-49 167.5 9.8 4.4e-49 167.2 9.8 1.1 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 EWM23641.1 - 0.00011 22.3 16.4 0.00011 22.3 16.4 2.7 2 1 0 2 2 2 1 EamA-like transporter family SLC35F PF06027.12 EWM23641.1 - 0.00049 19.7 8.1 0.00049 19.7 8.1 1.9 2 0 0 2 2 2 1 Solute carrier family 35 UAA PF08449.11 EWM23641.1 - 0.012 14.9 11.2 0.0065 15.7 8.7 1.8 2 1 0 2 2 2 0 UAA transporter family DUF3040 PF11239.8 EWM23641.1 - 1.8 8.9 14.4 2 8.8 0.8 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3040) DUF3185 PF11381.8 EWM23641.1 - 4.8 7.3 7.5 11 6.1 1.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) ETF PF01012.21 EWM23642.1 - 2.7e-43 148.0 3.5 3.9e-43 147.4 3.5 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain GrpE PF01025.19 EWM23643.1 - 1.3e-29 103.0 1.9 2.2e-29 102.3 1.9 1.3 1 0 0 1 1 1 1 GrpE OmpH PF03938.14 EWM23643.1 - 0.00087 19.6 1.4 0.011 16.0 1.4 2.1 1 1 0 1 1 1 1 Outer membrane protein (OmpH-like) Enkurin PF13864.6 EWM23643.1 - 0.11 12.9 2.0 0.27 11.7 0.3 2.1 2 0 0 2 2 2 0 Calmodulin-binding Prefoldin_2 PF01920.20 EWM23643.1 - 0.38 10.7 3.4 0.4 10.6 0.8 2.3 2 1 1 3 3 3 0 Prefoldin subunit PseudoU_synth_1 PF01416.20 EWM23644.1 - 9.8e-13 48.5 0.0 2.4e-09 37.6 0.0 2.7 2 1 0 2 2 2 2 tRNA pseudouridine synthase DNA_pol3_theta PF06440.11 EWM23644.1 - 0.005 16.5 0.6 0.01 15.5 0.6 1.5 1 0 0 1 1 1 1 DNA polymerase III, theta subunit adh_short PF00106.25 EWM23645.1 - 2.8e-48 164.0 0.0 5.2e-48 163.1 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EWM23645.1 - 3.7e-30 105.2 0.1 5.9e-30 104.5 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM23645.1 - 8.3e-12 45.4 0.1 1.1e-11 45.0 0.1 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EWM23645.1 - 0.051 12.7 0.0 0.095 11.8 0.0 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 EWM23645.1 - 0.065 12.7 0.1 0.27 10.6 0.1 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Maf_N PF08383.11 EWM23645.1 - 0.089 12.6 0.3 0.35 10.7 0.0 2.2 2 1 0 2 2 2 0 Maf N-terminal region ThylakoidFormat PF11264.8 EWM23646.1 - 0.15 11.7 0.0 0.19 11.4 0.0 1.1 1 0 0 1 1 1 0 Thylakoid formation protein Choline_transpo PF04515.12 EWM23647.1 - 1.9e-52 178.5 16.0 1.9e-52 178.5 16.0 2.4 2 1 1 3 3 3 1 Plasma-membrane choline transporter tRNA_U5-meth_tr PF05958.11 EWM23648.1 - 1.7e-57 195.0 0.0 2.6e-13 49.7 0.0 6.0 6 0 0 6 6 6 6 tRNA (Uracil-5-)-methyltransferase Methyltransf_25 PF13649.6 EWM23648.1 - 8.2e-06 26.4 0.0 2.2e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 EWM23648.1 - 2.6e-05 23.8 0.0 4.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.6 EWM23648.1 - 4.7e-05 23.2 0.0 8.4e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EWM23648.1 - 0.00036 20.2 0.0 0.0018 18.0 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 EWM23648.1 - 0.0016 19.0 0.0 0.0038 17.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 EWM23648.1 - 0.01 14.9 0.0 0.016 14.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.17 EWM23648.1 - 0.018 14.5 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase PCMT PF01135.19 EWM23648.1 - 0.044 13.5 0.0 0.1 12.4 0.0 1.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 EWM23648.1 - 0.046 13.1 0.0 0.072 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 EWM23648.1 - 0.093 13.5 0.0 0.19 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AAR2 PF05282.11 EWM23650.1 - 9.4e-60 202.9 0.0 4.5e-59 200.6 0.0 1.8 1 1 0 1 1 1 1 AAR2 protein Ribosomal_S21 PF01165.20 EWM23651.1 - 2.6e-17 62.2 4.4 3.6e-17 61.8 4.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S21 ChAPs PF09295.10 EWM23651.1 - 0.15 11.0 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) SAE2 PF08573.10 EWM23652.1 - 1.2e-07 32.8 11.0 1.3e-06 29.5 0.3 3.7 2 1 1 3 3 3 2 DNA repair protein endonuclease SAE2/CtIP C-terminus Bacillus_HBL PF05791.11 EWM23652.1 - 0.1 12.4 1.4 0.15 11.9 1.4 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF5094 PF17015.5 EWM23652.1 - 0.1 12.7 1.7 0.17 12.0 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) TMEM192 PF14802.6 EWM23652.1 - 2.8 7.0 4.6 4.2 6.4 4.6 1.2 1 0 0 1 1 1 0 TMEM192 family TPR_1 PF00515.28 EWM23653.1 - 1.1e-17 63.0 5.9 4.7e-08 32.5 0.1 4.3 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 EWM23653.1 - 4.4e-16 57.6 4.0 9e-06 25.4 0.1 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EWM23653.1 - 2.1e-11 43.1 3.4 0.0022 18.1 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 EWM23653.1 - 3.6e-10 39.8 3.6 1e-06 28.8 0.1 3.2 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EWM23653.1 - 3.1e-09 36.3 1.0 0.0019 17.8 0.2 3.8 3 1 1 4 4 4 3 TPR repeat TPR_16 PF13432.6 EWM23653.1 - 6.3e-09 36.3 13.6 1.5e-07 32.0 1.6 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EWM23653.1 - 2e-08 34.4 9.0 0.033 15.0 0.2 5.3 1 1 4 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EWM23653.1 - 1.4e-07 31.7 5.8 0.00068 19.9 0.3 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EWM23653.1 - 7e-07 29.7 2.1 0.0021 18.6 0.1 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EWM23653.1 - 2.4e-05 24.7 4.4 2.9 8.7 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EWM23653.1 - 5.3e-05 23.0 0.2 0.53 10.4 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EWM23653.1 - 0.001 19.3 10.0 0.059 13.8 0.1 4.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 EWM23653.1 - 0.002 17.4 1.6 1.2 8.3 0.0 3.1 1 1 1 3 3 3 1 Tetratricopeptide repeat MIT PF04212.18 EWM23653.1 - 0.013 15.6 1.0 18 5.5 0.0 3.6 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_4 PF07721.14 EWM23653.1 - 0.41 11.4 7.8 37 5.4 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat PAS_8 PF13188.7 EWM23655.1 - 0.00029 20.8 0.0 0.00067 19.6 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EWM23655.1 - 0.0009 19.2 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EWM23655.1 - 0.049 13.9 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 PAS fold DFRP_C PF16543.5 EWM23655.1 - 3.5 8.2 7.6 0.43 11.1 2.6 2.0 1 1 1 2 2 2 0 DRG Family Regulatory Proteins, Tma46 PA PF02225.22 EWM23657.1 - 1.4e-13 50.6 0.0 3.4e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 PA domain zf-RING_2 PF13639.6 EWM23657.1 - 5.3e-12 45.9 4.8 5.3e-12 45.9 4.8 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 EWM23657.1 - 3.6e-11 42.6 1.0 7e-11 41.7 1.0 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EWM23657.1 - 2.2e-10 40.2 5.1 2.2e-10 40.2 5.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EWM23657.1 - 2.3e-09 37.0 3.2 2.3e-09 37.0 3.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EWM23657.1 - 3.3e-06 27.3 6.6 1.6e-05 25.1 6.6 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EWM23657.1 - 8.4e-06 25.6 2.1 8.4e-06 25.6 2.1 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EWM23657.1 - 0.00015 21.7 2.4 0.00033 20.6 1.7 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EWM23657.1 - 0.00076 19.3 5.0 0.00076 19.3 5.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EWM23657.1 - 0.00089 19.3 2.3 0.00089 19.3 2.3 1.8 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 EWM23657.1 - 0.059 13.3 2.7 0.13 12.2 2.7 1.6 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.7 EWM23657.1 - 1.2 9.3 5.9 1.3 9.3 4.0 2.0 1 1 1 2 2 2 0 RING-variant domain DUF92 PF01940.16 EWM23658.1 - 3e-70 236.3 3.4 3.9e-70 235.9 3.4 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 CBFD_NFYB_HMF PF00808.23 EWM23659.1 - 4.8e-09 36.4 0.0 1.1e-08 35.2 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 EWM23659.1 - 0.0022 17.9 0.0 0.0034 17.3 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 EWM23659.1 - 0.0064 16.9 0.0 0.0083 16.5 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EWM23659.1 - 0.012 15.8 0.0 0.023 14.8 0.0 1.6 1 1 0 1 1 1 0 TATA box binding protein associated factor (TAF) Metallophos PF00149.28 EWM23660.1 - 8e-33 114.7 0.0 1.4e-32 113.9 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 EWM23660.1 - 3.3e-25 88.2 0.0 7.3e-25 87.1 0.0 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.28 EWM23660.1 - 1.9e-16 59.1 4.3 1.4e-05 24.7 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EWM23660.1 - 3.7e-16 57.9 5.7 0.00024 21.0 0.1 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 EWM23660.1 - 2.7e-08 33.8 1.3 0.00023 21.2 0.2 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EWM23660.1 - 5.9e-08 32.3 2.8 0.079 13.2 0.2 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EWM23660.1 - 1.2e-05 25.5 7.4 0.0018 18.6 0.6 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EWM23660.1 - 1.6e-05 25.5 5.8 0.00091 19.8 1.2 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EWM23660.1 - 3.3e-05 23.5 1.7 0.09 12.5 0.5 3.5 2 1 1 3 3 3 2 TPR repeat TPR_14 PF13428.6 EWM23660.1 - 4.2e-05 24.0 2.2 0.11 13.4 0.0 3.7 1 1 2 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.17 EWM23660.1 - 0.00052 20.5 1.3 0.0012 19.3 1.3 1.5 1 0 0 1 1 1 1 Bacterial transcriptional activator domain TPR_19 PF14559.6 EWM23660.1 - 0.0016 18.9 3.0 0.0081 16.6 0.4 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EWM23660.1 - 0.0024 17.8 0.3 0.21 11.7 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 EWM23660.1 - 0.0052 16.6 6.1 2.3 8.2 0.9 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EWM23660.1 - 0.0058 16.7 0.8 0.18 11.9 0.0 3.0 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 EWM23660.1 - 0.011 16.3 1.6 0.29 11.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 EWM23660.1 - 0.015 15.4 2.2 0.91 9.6 0.0 2.7 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_17 PF13431.6 EWM23660.1 - 0.033 14.6 1.6 0.33 11.4 0.1 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat YfiO PF13525.6 EWM23660.1 - 0.052 13.3 3.2 0.15 11.7 2.6 1.9 1 1 0 1 1 1 0 Outer membrane lipoprotein SRP_TPR_like PF17004.5 EWM23660.1 - 0.084 12.9 0.4 0.17 11.9 0.4 1.5 1 0 0 1 1 1 0 Putative TPR-like repeat DUF3856 PF12968.7 EWM23660.1 - 0.21 11.7 2.0 18 5.3 1.0 3.4 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) Choline_transpo PF04515.12 EWM23662.1 - 2.3e-82 276.8 29.6 2.3e-82 276.8 29.6 1.8 2 0 0 2 2 2 1 Plasma-membrane choline transporter TMEM192 PF14802.6 EWM23662.1 - 0.5 9.4 2.1 1.3 8.1 2.1 1.8 1 0 0 1 1 1 0 TMEM192 family Nucleoporin_C PF03177.14 EWM23663.1 - 2.1 7.0 9.1 0.29 9.8 3.9 2.1 2 1 0 2 2 2 0 Non-repetitive/WGA-negative nucleoporin C-terminal PUB PF09409.10 EWM23664.1 - 8.7e-17 60.8 0.0 1.5e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 PUB domain PDZ PF00595.24 EWM23664.1 - 1.3e-06 28.6 0.5 5.7e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EWM23664.1 - 2.4e-06 27.8 0.0 6.5e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EWM23664.1 - 0.00011 21.9 0.1 0.00022 21.0 0.1 1.5 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EWM23664.1 - 0.065 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Tricorn protease PDZ domain DER1 PF04511.15 EWM23665.1 - 1.1e-42 146.2 4.8 1.4e-42 145.8 4.8 1.1 1 0 0 1 1 1 1 Der1-like family DnaJ PF00226.31 EWM23666.1 - 1.1e-21 76.7 0.5 2.4e-21 75.6 0.5 1.6 1 0 0 1 1 1 1 DnaJ domain TcfC PF16967.5 EWM23666.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 E-set like domain STI1 PF17830.1 EWM23667.1 - 0.0037 17.1 0.1 0.0061 16.5 0.1 1.3 1 0 0 1 1 1 1 STI1 domain His_Phos_2 PF00328.22 EWM23668.1 - 2e-19 70.3 0.0 2.5e-11 43.6 0.0 2.4 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Pkinase PF00069.25 EWM23669.1 - 1.5e-51 175.3 0.0 8.3e-46 156.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EWM23669.1 - 1.2e-29 103.4 0.0 1.6e-27 96.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EWM23669.1 - 0.021 14.2 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 EWM23669.1 - 0.042 12.6 0.0 0.26 10.0 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase hNIFK_binding PF12196.8 EWM23669.1 - 0.32 10.5 0.0 0.32 10.5 0.0 2.2 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK Citrate_synt PF00285.21 EWM23670.1 - 2.1e-119 398.8 0.0 2.5e-119 398.6 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Met_10 PF02475.16 EWM23671.1 - 8.3e-58 195.4 0.1 2.7e-57 193.7 0.0 1.9 2 1 0 2 2 2 1 Met-10+ like-protein RNA_pol_Rpb1_5 PF04998.17 EWM23672.1 - 2.9e-87 292.5 0.0 4.5e-87 291.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 EWM23672.1 - 3.5e-83 279.5 0.0 4.8e-83 279.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 EWM23672.1 - 2.7e-72 242.4 0.0 6.3e-72 241.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EWM23672.1 - 5.2e-37 127.2 0.0 9.7e-37 126.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EWM23672.1 - 2.4e-26 91.8 0.0 6e-26 90.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 FA_hydroxylase PF04116.13 EWM23673.1 - 2.4e-26 92.6 8.3 2.4e-26 92.6 8.3 1.8 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily eRF1_1 PF03463.15 EWM23676.1 - 2.1e-48 163.6 0.0 3.1e-48 163.0 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 EWM23676.1 - 5.2e-28 98.0 0.0 7.6e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EWM23676.1 - 4.8e-19 68.9 0.0 1e-18 67.9 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 6PF2K PF01591.18 EWM23677.1 - 1.9e-69 233.4 0.1 2.7e-69 232.9 0.1 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EWM23677.1 - 1.3e-20 73.9 0.0 2.8e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EWM23677.1 - 7.9e-07 29.3 0.0 1.5e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EWM23677.1 - 0.017 14.6 0.0 0.037 13.5 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 HisKA_2 PF07568.12 EWM23677.1 - 0.11 12.6 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase bZIP_1 PF00170.21 EWM23679.1 - 1e-10 41.5 17.1 1e-10 41.5 17.1 2.5 2 1 1 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 EWM23679.1 - 9.5e-07 28.8 14.0 9.5e-07 28.8 14.0 2.2 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 EWM23679.1 - 0.00042 20.8 8.6 0.00042 20.8 8.6 3.1 3 0 0 3 3 3 1 bZIP Maf transcription factor DUF2218 PF09981.9 EWM23679.1 - 0.0099 16.3 1.7 0.83 10.1 0.6 2.4 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2218) MukF_M PF17192.4 EWM23679.1 - 0.063 13.0 7.2 0.055 13.2 0.7 2.3 2 0 0 2 2 2 0 MukF middle domain DUF4407 PF14362.6 EWM23679.1 - 0.34 10.2 6.5 1.1 8.5 4.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF1068 PF06364.12 EWM23679.1 - 3 7.7 8.8 0.89 9.4 2.9 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1068) TMF_TATA_bd PF12325.8 EWM23679.1 - 9.1 6.5 17.3 0.51 10.6 6.4 3.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding H_PPase PF03030.16 EWM23680.1 - 4.6e-250 831.7 32.1 5.7e-250 831.4 32.1 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase DUF1453 PF07301.11 EWM23680.1 - 0.28 11.2 0.1 0.28 11.2 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1453) PTR2 PF00854.21 EWM23683.1 - 2e-83 280.5 1.8 3.5e-69 233.5 0.2 2.4 2 1 0 2 2 2 2 POT family NnrU PF07298.11 EWM23683.1 - 0.34 10.4 0.0 0.34 10.4 0.0 3.1 3 1 1 4 4 4 0 NnrU protein AmoC PF04896.12 EWM23683.1 - 0.5 9.6 6.1 1.9 7.7 3.1 2.4 2 0 0 2 2 2 0 Ammonia monooxygenase/methane monooxygenase, subunit C Sulfate_transp PF00916.20 EWM23684.1 - 4.8e-98 328.4 11.6 5.8e-98 328.1 11.6 1.1 1 0 0 1 1 1 1 Sulfate permease family MFS_MOT1 PF16983.5 EWM23684.1 - 0.011 16.2 2.5 0.011 16.2 2.5 3.6 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily Mad3_BUB1_I PF08311.12 EWM23685.1 - 1.4e-06 28.3 0.2 2.6e-06 27.4 0.2 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 TPR_14 PF13428.6 EWM23685.1 - 1e-05 25.9 4.9 0.029 15.2 0.1 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EWM23685.1 - 0.0016 18.4 0.7 0.86 9.9 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EWM23685.1 - 0.0019 18.4 0.3 0.04 14.2 0.1 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EWM23685.1 - 0.0069 16.3 0.2 7.9 6.8 0.0 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat CMAS PF02353.20 EWM23685.1 - 0.053 12.8 0.5 8.2 5.6 0.0 2.3 1 1 1 2 2 2 0 Mycolic acid cyclopropane synthetase RabGAP-TBC PF00566.18 EWM23686.1 - 2e-41 142.1 0.0 4.7e-41 140.8 0.0 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Bax1-I PF01027.20 EWM23688.1 - 5.2e-44 150.5 29.7 6.2e-44 150.3 29.7 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 NCE101 PF11654.8 EWM23688.1 - 0.034 13.8 0.1 0.1 12.3 0.1 1.8 1 0 0 1 1 1 0 Non-classical export protein 1 CcmD PF04995.14 EWM23688.1 - 0.75 9.9 0.0 0.75 9.9 0.0 3.0 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) PHO4 PF01384.20 EWM23688.1 - 1.8 7.6 11.1 1.3 8.0 4.9 2.1 1 1 1 2 2 2 0 Phosphate transporter family AAA PF00004.29 EWM23689.1 - 7.5e-70 233.5 0.0 2.4e-43 147.7 0.0 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EWM23689.1 - 3.1e-24 84.5 3.2 1.9e-12 46.8 0.1 2.8 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EWM23689.1 - 7.9e-07 29.6 0.7 0.13 12.6 0.0 3.6 2 1 0 3 3 3 3 AAA ATPase domain AAA_2 PF07724.14 EWM23689.1 - 5.7e-05 23.3 0.0 0.006 16.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EWM23689.1 - 7.3e-05 22.6 0.0 0.00029 20.6 0.0 2.0 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EWM23689.1 - 0.00018 21.5 0.2 0.015 15.3 0.1 3.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EWM23689.1 - 0.0003 21.1 0.2 1.5 9.1 0.1 3.7 3 2 2 5 5 4 1 AAA domain AAA_25 PF13481.6 EWM23689.1 - 0.0019 17.8 0.6 0.74 9.4 0.1 3.1 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 EWM23689.1 - 0.014 15.3 0.0 0.028 14.3 0.0 1.4 2 0 0 2 2 2 0 Rad17 P-loop domain TIP49 PF06068.13 EWM23689.1 - 0.055 12.7 0.0 0.087 12.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 EWM23689.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EWM23689.1 - 0.11 12.5 0.0 0.73 9.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EWM23689.1 - 0.17 11.2 0.0 1.6 8.0 0.0 2.1 2 0 0 2 2 2 0 KaiC PEX11 PF05648.14 EWM23691.1 - 2.3e-32 112.3 0.4 1.1e-31 110.1 0.4 1.8 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Dehydrin PF00257.19 EWM23691.1 - 0.045 14.3 3.3 0.066 13.8 3.3 1.2 1 0 0 1 1 1 0 Dehydrin SR-25 PF10500.9 EWM23691.1 - 2.4 7.7 8.2 3.3 7.3 8.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AAA PF00004.29 EWM23692.1 - 1.8e-34 119.0 0.0 3.5e-34 118.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EWM23692.1 - 1.1e-06 28.5 0.0 3e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EWM23692.1 - 8e-05 22.7 0.1 0.0005 20.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ResIII PF04851.15 EWM23692.1 - 0.00057 19.9 0.0 0.0013 18.8 0.0 1.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 EWM23692.1 - 0.00061 20.2 0.1 0.006 17.0 0.1 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EWM23692.1 - 0.00089 19.5 0.4 0.58 10.4 0.0 3.2 2 1 2 4 4 4 1 AAA domain AAA_lid_3 PF17862.1 EWM23692.1 - 0.0022 17.8 0.1 0.014 15.2 0.1 2.3 3 0 0 3 3 3 1 AAA+ lid domain AAA_2 PF07724.14 EWM23692.1 - 0.0032 17.6 0.0 0.007 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EWM23692.1 - 0.013 15.7 0.0 0.033 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EWM23692.1 - 0.014 15.2 0.0 0.097 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EWM23692.1 - 0.068 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EWM23692.1 - 0.093 12.4 0.0 0.9 9.2 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 EWM23692.1 - 0.13 11.5 0.0 0.39 10.0 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin ATPase PF06745.13 EWM23692.1 - 0.21 10.9 0.1 8 5.7 0.0 2.1 1 1 1 2 2 2 0 KaiC Defensin_5 PF18251.1 EWM23694.1 - 0.031 14.3 0.0 0.097 12.8 0.0 1.8 1 0 0 1 1 1 0 Fungal defensin Copsin Hairy_orange PF07527.13 EWM23694.1 - 0.079 13.2 0.2 0.18 12.0 0.2 1.6 1 0 0 1 1 1 0 Hairy Orange DUF5079 PF16882.5 EWM23694.1 - 0.17 11.7 0.1 0.26 11.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5079) KxDL PF10241.9 EWM23694.1 - 0.5 10.7 5.0 1.6 9.1 1.5 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein FBPase PF00316.20 EWM23695.1 - 1.4e-53 181.1 0.1 1.9e-53 180.7 0.1 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 EWM23695.1 - 5.3e-05 22.9 0.1 0.00034 20.2 0.0 2.0 2 0 0 2 2 2 1 Inositol monophosphatase family IQ PF00612.27 EWM23696.1 - 0.038 13.8 0.1 0.093 12.6 0.1 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif Fib_alpha PF08702.10 EWM23696.1 - 8.2 6.6 16.3 7.8 6.7 5.0 2.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family GYF_2 PF14237.6 EWM23697.1 - 8.8e-21 73.5 1.1 5.7e-11 42.1 0.3 2.8 2 0 0 2 2 2 2 GYF domain 2 RRM_1 PF00076.22 EWM23697.1 - 8.5e-11 41.5 0.0 2e-05 24.3 0.0 3.9 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GYF PF02213.16 EWM23697.1 - 0.00094 18.8 2.6 1 9.1 0.0 2.9 2 0 0 2 2 2 2 GYF domain RRM_7 PF16367.5 EWM23697.1 - 0.0039 17.3 0.0 0.0074 16.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif CDC45 PF02724.14 EWM23697.1 - 0.14 10.5 2.0 0.21 9.9 2.0 1.4 1 0 0 1 1 1 0 CDC45-like protein CW_binding_1 PF01473.20 EWM23697.1 - 0.74 10.3 4.2 0.55 10.7 0.2 2.8 3 0 0 3 3 3 0 Putative cell wall binding repeat Gcd10p PF04189.13 EWM23698.1 - 8.1e-51 172.9 0.0 1.3e-50 172.3 0.0 1.3 1 0 0 1 1 1 1 Gcd10p family DAGAT PF03982.13 EWM23699.1 - 3.7e-29 101.6 0.0 5.6e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase tRNA-synt_1e PF01406.19 EWM23700.1 - 2.8e-106 355.3 0.0 3.9e-106 354.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EWM23700.1 - 2.4e-15 56.2 0.2 1.2e-07 30.8 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EWM23700.1 - 0.0021 16.4 0.0 0.14 10.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) MMR_HSR1_Xtn PF16897.5 EWM23702.1 - 4.6e-41 139.1 0.2 6.8e-41 138.6 0.2 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EWM23702.1 - 1.9e-19 69.8 0.0 4.2e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EWM23702.1 - 2.6e-10 40.0 0.1 3e-09 36.6 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EWM23702.1 - 0.0013 18.8 0.2 0.23 11.5 0.0 2.3 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 EWM23702.1 - 0.0018 17.3 0.3 0.0059 15.6 0.1 1.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AIG1 PF04548.16 EWM23702.1 - 0.08 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 AIG1 family FNIP_N PF14636.6 EWM23703.1 - 2.1 9.3 10.5 1.2 10.0 7.5 2.0 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus Ndc1_Nup PF09531.10 EWM23703.1 - 5.6 5.5 8.5 6 5.4 8.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF959 PF06121.14 EWM23703.1 - 7.6 6.8 13.6 24 5.1 13.6 1.9 1 1 0 1 1 1 0 Domain of Unknown Function (DUF959) Prismane PF03063.20 EWM23704.1 - 8.8e-148 493.2 0.0 1.3e-147 492.6 0.0 1.2 1 0 0 1 1 1 1 Prismane/CO dehydrogenase family DSPc PF00782.20 EWM23705.1 - 5.1e-09 36.1 0.0 9.4e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EWM23705.1 - 0.046 13.3 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EWM23705.1 - 0.063 13.2 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family AAA_16 PF13191.6 EWM23706.1 - 0.0015 19.0 0.1 0.003 18.0 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EWM23706.1 - 0.011 15.4 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 EWM23706.1 - 0.084 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 EWM23706.1 - 0.094 13.0 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EWM23706.1 - 0.12 12.9 0.0 0.25 11.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 EWM23706.1 - 0.13 12.2 0.4 0.28 11.2 0.4 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 EWM23706.1 - 0.24 11.8 0.4 0.43 11.0 0.4 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NUC153 PF08159.12 EWM23707.1 - 1.5e-09 37.5 2.3 2.7e-09 36.7 2.3 1.4 1 0 0 1 1 1 1 NUC153 domain ANAPC4_WD40 PF12894.7 EWM23707.1 - 0.0017 18.6 0.0 0.24 11.7 0.0 2.8 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EWM23707.1 - 0.032 15.1 0.0 74 4.5 0.0 4.5 5 0 0 5 5 5 0 WD domain, G-beta repeat Kinesin PF00225.23 EWM23708.1 - 2.2e-95 319.4 0.0 4.9e-95 318.3 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EWM23708.1 - 1.2e-48 164.8 0.0 3.7e-48 163.3 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding Pox_F11 PF04943.12 EWM23708.1 - 1 8.4 4.9 1.5 7.8 0.0 2.5 2 0 0 2 2 2 0 Poxvirus F11 protein Chloroa_b-bind PF00504.21 EWM23709.1 - 1.1e-08 35.8 1.0 2.2e-08 34.8 0.7 1.7 1 1 0 1 1 1 1 Chlorophyll A-B binding protein CopD PF05425.13 EWM23709.1 - 0.57 10.6 8.5 1.4 9.4 0.4 3.3 2 1 1 3 3 3 0 Copper resistance protein D VPS28 PF03997.12 EWM23710.1 - 1.8e-62 210.4 0.0 2.1e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 VPS28 protein SHOCT PF09851.9 EWM23710.1 - 0.041 13.6 0.2 14 5.5 0.0 2.7 2 0 0 2 2 2 0 Short C-terminal domain RecC_C PF17946.1 EWM23710.1 - 0.064 13.0 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 RecC C-terminal domain MFS_5 PF05631.14 EWM23712.1 - 4.5e-28 98.2 2.3 5.8e-28 97.8 2.3 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 EWM23712.1 - 3.6e-06 26.1 17.6 3.6e-06 26.1 17.6 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_5 PF05631.14 EWM23713.1 - 5e-09 35.5 0.0 6.2e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM Acylphosphatase PF00708.18 EWM23714.1 - 1.7e-14 54.0 0.1 2.1e-14 53.7 0.1 1.1 1 0 0 1 1 1 1 Acylphosphatase DUF2871 PF11070.8 EWM23714.1 - 0.047 14.0 0.1 0.064 13.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2871) SR-25 PF10500.9 EWM23717.1 - 0.0002 21.1 7.5 0.00029 20.5 7.5 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein AAA_33 PF13671.6 EWM23717.1 - 0.0019 18.4 0.0 0.023 14.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain DUF3446 PF11928.8 EWM23717.1 - 0.01 16.1 7.1 0.021 15.1 7.1 1.6 1 0 0 1 1 1 0 Early growth response N-terminal domain AAA_28 PF13521.6 EWM23717.1 - 0.033 14.4 0.0 0.055 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EWM23717.1 - 0.16 12.5 0.0 0.3 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 EWM23717.1 - 0.21 11.0 0.0 0.56 9.6 0.0 1.6 2 0 0 2 2 2 0 ADP-ribosylation factor family Herpes_pp85 PF04637.12 EWM23717.1 - 7.8 4.8 6.8 11 4.3 6.8 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) IMUP PF15761.5 EWM23717.1 - 8 7.2 11.3 17 6.1 11.3 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein PAS_4 PF08448.10 EWM23721.1 - 1.8e-09 37.8 0.0 3.2e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 EWM23721.1 - 2.3e-05 24.3 0.0 5.1e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 EWM23721.1 - 0.0028 17.9 0.0 0.099 12.9 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 EWM23721.1 - 0.012 15.9 0.0 0.021 15.0 0.0 1.5 1 0 0 1 1 1 0 PAS domain bZIP_1 PF00170.21 EWM23721.1 - 0.38 10.9 4.1 0.74 9.9 4.1 1.4 1 0 0 1 1 1 0 bZIP transcription factor TMF_DNA_bd PF12329.8 EWM23722.1 - 0.0091 16.0 4.1 0.013 15.4 4.1 1.2 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 EWM23722.1 - 0.018 15.3 6.4 0.029 14.6 6.4 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 EWM23722.1 - 0.057 13.5 0.3 0.078 13.1 0.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DHR10 PF18595.1 EWM23722.1 - 0.086 12.9 4.6 0.17 12.0 4.6 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain GAS PF13851.6 EWM23722.1 - 0.44 9.9 3.8 0.64 9.3 3.8 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ADIP PF11559.8 EWM23722.1 - 0.59 10.2 4.4 0.88 9.7 4.4 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding EAF PF09816.9 EWM23724.1 - 2.4e-07 31.1 0.0 3.1e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Lactamase_B_3 PF13483.6 EWM23726.1 - 4.2e-11 43.0 0.0 1.2e-08 35.1 0.0 2.1 2 0 0 2 2 2 2 Beta-lactamase superfamily domain DUF4589 PF15252.6 EWM23726.1 - 0.18 11.8 1.5 0.26 11.3 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) CD52 PF15116.6 EWM23729.1 - 0.32 11.0 1.5 2.3 8.3 0.2 2.5 2 1 0 2 2 2 0 CAMPATH-1 antigen DUF1754 PF08555.10 EWM23731.1 - 0.0064 17.3 2.9 0.0064 17.3 2.9 2.1 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) Cyto_heme_lyase PF01265.17 EWM23732.1 - 1.9e-51 175.4 7.8 3e-49 168.2 7.8 2.1 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Patched PF02460.18 EWM23733.1 - 1.2e-48 165.9 0.0 4.6e-30 104.4 0.0 2.4 2 1 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 EWM23733.1 - 9.6e-39 132.7 16.1 2.4e-21 76.2 0.6 3.7 4 1 1 5 5 5 2 Sterol-sensing domain of SREBP cleavage-activation DUF3693 PF12472.8 EWM23733.1 - 0.79 9.4 0.0 0.79 9.4 0.0 2.9 3 0 0 3 3 3 0 Phage related protein Zn_clus PF00172.18 EWM23734.1 - 1.3e-06 28.5 6.5 2e-06 27.8 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RhoGEF PF00621.20 EWM23739.1 - 6.5e-11 42.8 0.0 2.4e-10 40.9 0.0 1.9 1 1 0 1 1 1 1 RhoGEF domain PH_13 PF16652.5 EWM23739.1 - 0.033 14.0 0.2 0.23 11.3 0.1 2.2 1 1 0 2 2 2 0 Pleckstrin homology domain NRN1 PF15056.6 EWM23739.1 - 0.12 12.5 0.1 0.3 11.2 0.1 1.7 1 0 0 1 1 1 0 Neuritin protein family PH PF00169.29 EWM23739.1 - 0.14 12.7 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 PH domain Ribosomal_L30_N PF08079.12 EWM23743.1 - 9.3e-14 51.4 9.4 1.5e-13 50.8 9.4 1.3 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain YebO PF13974.6 EWM23743.1 - 0.045 13.8 0.3 0.066 13.3 0.3 1.2 1 0 0 1 1 1 0 YebO-like protein API5 PF05918.11 EWM23743.1 - 0.15 10.9 1.0 0.16 10.7 1.0 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) TPR_11 PF13414.6 EWM23747.1 - 1.9e-09 37.0 0.6 2.7e-07 30.1 0.3 2.3 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.17 EWM23747.1 - 3.5e-09 36.1 3.0 2.2e-06 27.3 0.4 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EWM23747.1 - 6.2e-08 32.1 2.5 2.5e-06 27.1 0.4 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EWM23747.1 - 0.00048 20.7 0.1 0.00091 19.8 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 EWM23747.1 - 0.001 19.3 1.2 0.0079 16.5 0.1 2.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EWM23747.1 - 0.0019 18.3 1.5 0.016 15.4 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EWM23747.1 - 0.002 18.6 0.1 0.0036 17.8 0.1 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 EWM23747.1 - 0.0028 17.9 0.1 0.71 10.4 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EWM23747.1 - 0.0049 16.8 0.1 0.026 14.6 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EWM23747.1 - 0.0071 17.1 0.1 0.024 15.4 0.0 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EWM23747.1 - 0.014 15.5 0.1 0.79 9.9 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EWM23747.1 - 0.028 14.5 0.1 3.3 7.8 0.0 2.5 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat DUF357 PF04010.13 EWM23747.1 - 0.18 11.9 2.0 0.27 11.4 0.7 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF357) PT PF04886.12 EWM23750.1 - 0.00083 18.9 18.1 0.00083 18.9 18.1 4.1 1 1 1 2 2 2 1 PT repeat PTPA PF03095.15 EWM23753.1 - 9.9e-23 81.0 0.0 1.2e-22 80.8 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Cys_Met_Meta_PP PF01053.20 EWM23757.1 - 4.2e-130 433.7 0.0 4.8e-130 433.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EWM23757.1 - 3.4e-06 26.5 0.0 6.3e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EWM23757.1 - 6.3e-06 25.7 0.0 4.6e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 EWM23757.1 - 0.0053 15.3 0.1 0.008 14.7 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase ThiG PF05690.14 EWM23757.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Beta_elim_lyase PF01212.21 EWM23757.1 - 0.12 11.7 0.0 3.5 6.8 0.0 2.2 2 0 0 2 2 2 0 Beta-eliminating lyase Aminotran_5 PF00266.19 EWM23757.1 - 0.14 11.1 0.1 0.67 8.8 0.0 2.0 3 0 0 3 3 3 0 Aminotransferase class-V ABC_membrane_2 PF06472.15 EWM23759.1 - 5e-37 127.8 0.0 5.8e-37 127.6 0.0 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 TauD PF02668.16 EWM23759.1 - 0.019 14.7 0.0 0.027 14.3 0.0 1.1 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family ABC_membrane_2 PF06472.15 EWM23760.1 - 4.4e-23 82.0 0.1 6.6e-23 81.5 0.1 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 CCDC53 PF10152.9 EWM23760.1 - 0.0026 18.2 0.0 0.0039 17.6 0.0 1.2 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex CAP_N PF01213.19 EWM23760.1 - 0.074 12.5 2.2 0.1 12.1 2.2 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 EWM23760.1 - 0.44 10.6 3.6 0.62 10.1 3.6 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Phospholip_B PF04916.13 EWM23764.1 - 2.6e-25 89.0 0.0 3.9e-25 88.4 0.0 1.2 1 1 0 1 1 1 1 Phospholipase B MRFAP1 PF15155.6 EWM23765.1 - 0.032 14.8 0.4 0.036 14.6 0.4 1.2 1 0 0 1 1 1 0 MORF4 family-associated protein1 AAA_22 PF13401.6 EWM23766.1 - 8.6e-05 22.8 0.0 0.00016 21.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EWM23766.1 - 0.00014 22.3 0.1 0.00023 21.6 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EWM23766.1 - 0.00092 19.6 0.0 0.0017 18.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EWM23766.1 - 0.0012 18.8 0.0 0.0028 17.6 0.0 1.6 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.6 EWM23766.1 - 0.0031 17.5 0.0 0.0058 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 EWM23766.1 - 0.011 15.0 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_25 PF13481.6 EWM23766.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EWM23766.1 - 0.054 13.2 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 EWM23766.1 - 0.071 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Thymidylate_kin PF02223.17 EWM23766.1 - 0.078 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Thymidylate kinase ABC_tran PF00005.27 EWM23766.1 - 0.13 12.8 0.0 0.24 11.9 0.0 1.3 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 EWM23766.1 - 0.14 12.6 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase GREB1 PF15782.5 EWM23766.1 - 0.14 9.3 2.4 0.21 8.7 2.4 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AAA_33 PF13671.6 EWM23766.1 - 0.17 12.0 0.0 0.26 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EWM23766.1 - 0.18 11.5 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 EWM23766.1 - 0.19 11.2 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RAP1 PF07218.11 EWM23766.1 - 2.9 6.1 6.3 3.6 5.8 6.3 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Mito_fiss_reg PF05308.11 EWM23767.1 - 9.5 6.2 7.0 10 6.1 6.6 1.3 1 1 0 1 1 1 0 Mitochondrial fission regulator BNR_3 PF13859.6 EWM23769.1 - 0.43 9.8 1.8 0.39 10.0 0.7 1.5 1 1 1 2 2 2 0 BNR repeat-like domain DUF456 PF04306.13 EWM23774.1 - 2.7e-05 24.5 1.2 2.9e-05 24.4 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF456) Zip PF02535.22 EWM23774.1 - 0.0015 17.8 0.9 0.0015 17.8 0.9 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter MAP17 PF15807.5 EWM23774.1 - 0.047 13.9 0.4 0.05 13.8 0.4 1.0 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 SK_channel PF03530.14 EWM23774.1 - 0.056 13.4 0.1 0.062 13.3 0.1 1.0 1 0 0 1 1 1 0 Calcium-activated SK potassium channel Sortilin-Vps10 PF15902.5 EWM23775.1 - 6.6e-06 25.2 1.1 8.5e-06 24.8 1.1 1.2 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, PSII_BNR PF14870.6 EWM23775.1 - 0.00024 20.5 3.9 0.00028 20.2 3.9 1.1 1 0 0 1 1 1 1 Photosynthesis system II assembly factor YCF48 BNR_3 PF13859.6 EWM23775.1 - 0.00097 18.5 4.4 0.048 13.0 0.2 2.0 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.20 EWM23775.1 - 0.46 10.7 0.0 0.46 10.7 0.0 3.7 5 0 0 5 5 5 0 BNR/Asp-box repeat E1-E2_ATPase PF00122.20 EWM23776.1 - 5e-44 150.0 0.9 1.1e-43 148.9 0.9 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EWM23776.1 - 1.7e-35 123.2 0.1 4.4e-35 121.9 0.1 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EWM23776.1 - 9e-29 99.7 5.6 4.5e-12 46.2 0.4 4.1 4 0 0 4 4 4 3 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EWM23776.1 - 0.00037 20.3 0.7 0.00057 19.7 0.7 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Rhodanese PF00581.20 EWM23777.1 - 2.8e-21 76.0 0.0 2e-11 44.3 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain Rhodanese PF00581.20 EWM23778.1 - 2.5e-18 66.5 0.0 4.2e-08 33.7 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain RCC1 PF00415.18 EWM23779.1 - 3.4e-27 94.8 15.2 4.3e-09 36.9 0.3 6.7 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EWM23779.1 - 2.1e-17 62.4 17.3 3.7e-05 23.4 0.4 5.3 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat DUF4213 PF13938.6 EWM23779.1 - 1.4 9.2 6.5 3.4 8.0 0.3 3.8 4 1 0 4 4 4 0 Putative heavy-metal chelation RCC1 PF00415.18 EWM23780.1 - 1.1e-30 105.9 16.0 3.6e-09 37.1 0.3 6.9 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EWM23780.1 - 7e-18 63.9 16.8 3.2e-05 23.6 0.4 5.4 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat DUF4213 PF13938.6 EWM23780.1 - 1.3 9.3 7.3 3.1 8.1 0.4 4.0 4 1 0 4 4 4 0 Putative heavy-metal chelation SGL PF08450.12 EWM23782.1 - 1.3e-66 224.7 0.0 1.5e-66 224.5 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 EWM23782.1 - 0.17 11.9 0.9 0.5 10.4 0.1 2.2 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Lactonase PF10282.9 EWM23782.1 - 0.24 10.6 0.0 0.34 10.1 0.0 1.2 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller ThylakoidFormat PF11264.8 EWM23783.1 - 1.3e-10 41.3 0.1 1.7e-10 41.0 0.1 1.1 1 0 0 1 1 1 1 Thylakoid formation protein NUDIX PF00293.28 EWM23784.1 - 0.00096 19.2 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DUF4667 PF15700.5 EWM23786.1 - 0.00017 21.8 7.1 0.00022 21.4 7.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4667) SPX PF03105.19 EWM23786.1 - 0.0019 18.2 9.4 0.0019 18.2 9.4 1.2 1 0 0 1 1 1 1 SPX domain Peroxin-3 PF04882.12 EWM23786.1 - 0.018 14.0 1.1 0.018 14.1 1.1 1.1 1 0 0 1 1 1 0 Peroxin-3 Apt1 PF10351.9 EWM23786.1 - 0.27 10.0 9.0 0.31 9.8 9.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOG2 PF10428.9 EWM23786.1 - 2.2 7.4 19.1 2.7 7.1 19.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Trs65 PF12735.7 EWM23786.1 - 2.4 7.5 9.4 3.1 7.1 9.4 1.1 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 DUF1635 PF07795.11 EWM23786.1 - 4.6 7.0 13.5 7.5 6.3 13.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) AF-4 PF05110.13 EWM23786.1 - 6.2 4.8 35.4 7.7 4.5 35.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Miga PF10265.9 EWM23786.1 - 9.4 5.1 8.1 13 4.6 8.1 1.1 1 0 0 1 1 1 0 Mitoguardin PPR PF01535.20 EWM23788.1 - 0.015 15.5 0.4 5.1 7.6 0.0 2.7 3 1 0 3 3 3 0 PPR repeat AAA_12 PF13087.6 EWM23790.1 - 1.9e-47 161.5 0.0 2.7e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EWM23790.1 - 7.3e-25 88.2 0.0 6e-13 49.2 0.1 2.4 2 1 1 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 EWM23790.1 - 3.1e-11 43.5 0.0 0.005 16.6 0.0 3.2 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 EWM23790.1 - 1.4e-05 24.9 0.0 0.0013 18.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EWM23790.1 - 1.7e-05 25.1 0.0 0.059 13.6 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 EWM23790.1 - 6.7e-05 23.3 0.0 0.012 15.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 EWM23790.1 - 0.00026 20.7 0.3 0.001 18.8 0.1 2.2 3 0 0 3 3 3 1 UvrD-like helicase C-terminal domain PhoH PF02562.16 EWM23790.1 - 0.05 13.1 0.0 0.39 10.1 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein DUF2439 PF10382.9 EWM23792.1 - 2.8e-11 43.6 0.0 4.7e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) E_Pc_C PF06752.12 EWM23792.1 - 9.2 6.3 7.2 16 5.5 7.2 1.4 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus Glyco_hydro_9 PF00759.19 EWM23793.1 - 0.025 14.0 0.1 0.035 13.5 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 DUF1275 PF06912.11 EWM23794.1 - 0.052 13.5 1.5 0.064 13.2 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) Pkinase PF00069.25 EWM23795.1 - 0.00015 21.3 0.0 0.00016 21.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM23795.1 - 0.0037 16.6 0.0 0.0042 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Abhydrolase_1 PF00561.20 EWM23796.1 - 5.9e-23 81.8 0.0 7.6e-23 81.5 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EWM23796.1 - 2.5e-14 53.1 0.0 4.4e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EWM23796.1 - 1.9e-12 48.2 6.8 6.3e-12 46.6 6.8 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.12 EWM23796.1 - 0.00041 19.5 0.0 0.00059 19.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Thioesterase PF00975.20 EWM23796.1 - 0.006 16.7 0.0 0.0083 16.3 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 EWM23796.1 - 0.1 12.2 0.2 1.4 8.5 0.2 2.2 1 1 0 1 1 1 0 Putative esterase K_channel_TID PF07941.11 EWM23796.1 - 0.48 10.9 3.9 1.1 9.7 3.9 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Abhydrolase_1 PF00561.20 EWM23797.1 - 5.9e-23 81.8 0.0 7.6e-23 81.5 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EWM23797.1 - 2.5e-14 53.1 0.0 4.4e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EWM23797.1 - 1.9e-12 48.2 6.8 6.3e-12 46.6 6.8 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.12 EWM23797.1 - 0.00041 19.5 0.0 0.00059 19.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Thioesterase PF00975.20 EWM23797.1 - 0.006 16.7 0.0 0.0083 16.3 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 EWM23797.1 - 0.1 12.2 0.2 1.4 8.5 0.2 2.2 1 1 0 1 1 1 0 Putative esterase K_channel_TID PF07941.11 EWM23797.1 - 0.48 10.9 3.9 1.1 9.7 3.9 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain DUF3446 PF11928.8 EWM23798.1 - 0.016 15.5 14.2 0.022 15.0 14.2 1.2 1 0 0 1 1 1 0 Early growth response N-terminal domain Kinesin PF00225.23 EWM23801.1 - 1.3e-91 307.0 0.0 1.7e-91 306.7 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EWM23801.1 - 9.6e-19 67.8 0.0 3.6e-18 65.9 0.0 1.9 1 1 0 1 1 1 1 Microtubule binding Symplekin_C PF12295.8 EWM23806.1 - 2.9e-15 56.8 0.1 3.3e-15 56.7 0.1 1.1 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal Dynamin_N PF00350.23 EWM23811.1 - 2.6e-06 27.6 0.3 1.3e-05 25.3 0.0 2.3 2 1 0 2 2 2 1 Dynamin family EHD_N PF16880.5 EWM23811.1 - 5.6e-05 22.9 1.1 0.00014 21.7 1.1 1.7 1 0 0 1 1 1 1 N-terminal EH-domain containing protein MMR_HSR1 PF01926.23 EWM23811.1 - 0.04 14.0 0.0 0.091 12.8 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_7 PF12775.7 EWM23811.1 - 0.056 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 EWM23811.1 - 0.089 13.0 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2201_N PF13203.6 EWM23812.1 - 2.9 7.4 5.9 0.52 9.9 1.0 2.1 2 0 0 2 2 2 0 Putative metallopeptidase domain DUF5600 PF18150.1 EWM23813.1 - 0.12 13.0 0.1 0.16 12.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5600) Tetraspanin PF00335.20 EWM23814.1 - 0.53 10.0 4.2 0.1 12.3 0.7 1.6 2 0 0 2 2 2 0 Tetraspanin family Zn_clus PF00172.18 EWM23815.1 - 5.1e-05 23.3 12.8 8.9e-05 22.5 12.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PPR_2 PF13041.6 EWM23818.1 - 2.5e-56 187.7 1.5 1.9e-08 34.4 0.0 9.0 4 1 5 9 9 9 8 PPR repeat family PPR_3 PF13812.6 EWM23818.1 - 3e-49 164.9 0.0 9.6e-09 35.2 0.0 7.8 5 2 3 8 8 8 7 Pentatricopeptide repeat domain PPR PF01535.20 EWM23818.1 - 2.1e-42 140.4 11.0 3.2e-06 27.0 0.0 9.7 10 0 0 10 10 9 8 PPR repeat PPR_1 PF12854.7 EWM23818.1 - 1.7e-37 126.8 0.0 0.00021 20.9 0.0 10.5 11 0 0 11 11 11 6 PPR repeat PPR_long PF17177.4 EWM23818.1 - 8.1e-24 84.2 5.4 1e-08 34.9 0.5 3.9 2 1 2 4 4 4 4 Pentacotripeptide-repeat region of PRORP ELYS PF13934.6 EWM23818.1 - 0.0045 17.0 2.5 4.9 7.1 0.1 3.2 1 1 1 3 3 3 2 Nuclear pore complex assembly TPR_15 PF13429.6 EWM23818.1 - 0.005 16.1 3.7 0.8 8.9 0.4 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat Clathrin PF00637.20 EWM23818.1 - 0.0069 16.3 0.0 1.8 8.4 0.0 3.6 2 1 1 4 4 4 1 Region in Clathrin and VPS YtzH PF14165.6 EWM23818.1 - 0.019 15.4 0.0 0.059 13.8 0.0 1.8 2 0 0 2 2 2 0 YtzH-like protein TPR_19 PF14559.6 EWM23818.1 - 0.02 15.4 9.8 5.2 7.6 0.3 5.1 4 1 2 6 6 6 0 Tetratricopeptide repeat HGD-D PF06050.13 EWM23818.1 - 0.075 12.8 0.1 0.075 12.8 0.1 2.0 1 1 1 2 2 2 0 2-hydroxyglutaryl-CoA dehydratase, D-component TPR_14 PF13428.6 EWM23818.1 - 0.1 13.5 21.1 27 5.9 0.2 7.7 4 3 5 9 9 9 0 Tetratricopeptide repeat TPR_7 PF13176.6 EWM23818.1 - 0.2 11.8 1.2 33 4.8 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat BTAD PF03704.17 EWM23818.1 - 0.46 10.9 15.2 4.6 7.7 1.4 4.4 3 2 1 4 4 4 0 Bacterial transcriptional activator domain WD40 PF00400.32 EWM23821.1 - 1.2e-12 48.1 0.1 1.1e-08 35.6 0.0 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat FAD_binding_3 PF01494.19 EWM23823.1 - 7e-18 65.0 0.0 3e-05 23.4 0.0 3.2 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.24 EWM23823.1 - 2.3e-06 27.5 0.0 1.6e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EWM23823.1 - 3.3e-05 24.0 0.0 0.00018 21.7 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Glu_dehyd_C PF16912.5 EWM23823.1 - 0.00029 20.4 0.0 0.00048 19.7 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Pyr_redox_2 PF07992.14 EWM23823.1 - 0.0013 18.1 0.0 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 EWM23823.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 ThiF family HI0933_like PF03486.14 EWM23823.1 - 0.061 12.0 0.0 0.09 11.5 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 EWM23823.1 - 0.067 12.0 0.0 3.7 6.3 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.6 EWM23823.1 - 0.078 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EWM23823.1 - 0.24 10.6 0.0 0.36 10.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sigma70_r4_2 PF08281.12 EWM23824.1 - 0.013 15.1 1.4 0.05 13.3 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 PRIMA1 PF16101.5 EWM23824.1 - 1 9.4 6.9 3 7.9 0.7 2.2 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 ParA PF10609.9 EWM23827.1 - 3e-65 220.1 0.0 1.8e-64 217.6 0.0 2.1 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EWM23827.1 - 1e-12 48.2 0.0 1.6e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EWM23827.1 - 7.4e-10 39.0 0.3 5.1e-09 36.3 0.2 2.0 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 EWM23827.1 - 1.6e-07 30.9 0.4 3.1e-07 30.0 0.1 1.5 2 0 0 2 2 2 1 ATPase MipZ FeS_assembly_P PF01883.19 EWM23827.1 - 1.1e-05 25.5 0.0 3.8e-05 23.8 0.0 2.0 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein ArsA_ATPase PF02374.15 EWM23827.1 - 0.00018 20.8 0.6 0.0014 17.9 0.2 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase VirC1 PF07015.11 EWM23827.1 - 0.00089 18.6 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 VirC1 protein Fer4_NifH PF00142.18 EWM23827.1 - 0.004 16.6 0.1 0.0066 15.9 0.1 1.3 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 EWM23827.1 - 0.005 16.4 0.7 0.015 14.8 0.3 1.8 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ MeaB PF03308.16 EWM23827.1 - 0.013 14.5 0.1 0.022 13.7 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FTHFS PF01268.19 EWM23827.1 - 0.016 13.4 0.2 0.025 12.8 0.2 1.2 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase AAA_25 PF13481.6 EWM23827.1 - 0.029 14.0 0.1 0.06 12.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain CLP1_P PF16575.5 EWM23827.1 - 0.074 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Coiled PF05710.12 EWM23827.1 - 0.75 10.7 5.8 0.49 11.3 0.3 2.5 2 0 0 2 2 2 0 Coiled coil Yip1 PF04893.17 EWM23828.1 - 1.9e-09 37.4 16.4 3.3e-09 36.7 16.4 1.4 1 1 0 1 1 1 1 Yip1 domain YIF1 PF03878.15 EWM23828.1 - 9.8e-08 31.8 1.0 3.3e-06 26.8 1.0 2.2 1 1 0 1 1 1 1 YIF1 RL11D PF11088.8 EWM23829.1 - 0.089 13.1 0.5 0.15 12.4 0.5 1.3 1 0 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 E1-E2_ATPase PF00122.20 EWM23830.1 - 4e-46 156.8 7.0 4e-46 156.8 7.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EWM23830.1 - 3.2e-35 121.5 0.2 3.2e-35 121.5 0.2 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EWM23830.1 - 1.3e-20 74.6 3.0 5e-20 72.7 2.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EWM23830.1 - 6.7e-12 44.9 0.0 1.3e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EWM23830.1 - 2.5e-11 43.5 0.0 4.7e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EWM23830.1 - 7.9e-06 25.8 1.7 0.00027 20.7 0.5 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EWM23830.1 - 0.013 15.9 0.1 0.048 14.1 0.1 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase TraD PF06412.11 EWM23830.1 - 0.22 11.4 0.5 0.75 9.6 0.5 1.9 1 0 0 1 1 1 0 Conjugal transfer protein TraD Mpv17_PMP22 PF04117.12 EWM23833.1 - 4.1e-10 39.7 0.5 4.1e-10 39.7 0.5 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family TFIIA PF03153.13 EWM23833.1 - 0.0099 15.9 6.4 0.013 15.5 6.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 EWM23833.1 - 0.021 13.2 13.5 0.027 12.8 13.5 1.2 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rpc4 PF05132.14 EWM23833.1 - 0.38 11.2 2.2 0.6 10.5 2.2 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Connexin PF00029.19 EWM23833.1 - 0.84 9.3 3.6 1.2 8.8 3.6 1.2 1 0 0 1 1 1 0 Connexin CPSF100_C PF13299.6 EWM23833.1 - 1.4 9.1 7.3 2.1 8.5 7.3 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal PPL5 PF18168.1 EWM23833.1 - 3.8 6.7 8.1 5.7 6.1 8.1 1.1 1 0 0 1 1 1 0 Prim-pol family 5 NOA36 PF06524.12 EWM23833.1 - 8.1 5.7 22.4 12 5.1 22.4 1.2 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 EWM23833.1 - 8.9 6.0 23.0 18 4.9 23.0 1.4 1 0 0 1 1 1 0 FAM176 family RNA_polI_A34 PF08208.11 EWM23833.1 - 10 6.2 14.7 16 5.5 14.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DSBA PF01323.20 EWM23834.1 - 3.7e-09 36.6 0.8 4.9e-07 29.7 0.8 2.1 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 EWM23834.1 - 7.2e-07 29.5 0.0 9.6e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin EF-hand_7 PF13499.6 EWM23835.1 - 1.7e-05 25.2 0.3 0.00011 22.6 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair COPI_assoc PF08507.10 EWM23835.1 - 6.9e-05 22.9 1.6 0.0037 17.3 0.8 2.3 2 0 0 2 2 2 1 COPI associated protein DUF202 PF02656.15 EWM23835.1 - 0.019 15.4 1.4 0.053 14.0 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF5580 PF17743.1 EWM23835.1 - 0.02 13.5 0.8 0.053 12.1 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5580) EF-hand_1 PF00036.32 EWM23835.1 - 0.21 11.2 0.0 0.41 10.3 0.0 1.5 1 0 0 1 1 1 0 EF hand NDK PF00334.19 EWM23836.1 - 3.7e-53 179.2 0.0 4.9e-53 178.8 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Pro_isomerase PF00160.21 EWM23837.1 - 3.1e-14 53.5 0.0 4.6e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF1349 PF07081.11 EWM23837.1 - 0.072 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1349) PsbQ PF05757.11 EWM23838.1 - 2.3e-05 24.3 5.7 3e-05 23.9 5.7 1.1 1 0 0 1 1 1 1 Oxygen evolving enhancer protein 3 (PsbQ) DUF4327 PF14217.6 EWM23838.1 - 0.0011 19.1 0.1 0.0018 18.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4327) MutS_III PF05192.18 EWM23838.1 - 0.0082 16.4 1.2 0.011 15.9 1.2 1.1 1 0 0 1 1 1 1 MutS domain III RPN13_C PF16550.5 EWM23838.1 - 0.019 15.1 0.3 0.043 14.0 0.2 1.7 2 0 0 2 2 2 0 UCH-binding domain Cut8 PF08559.10 EWM23838.1 - 0.031 13.9 0.0 0.035 13.7 0.0 1.1 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein FUSC-like PF12805.7 EWM23838.1 - 0.08 12.0 0.2 0.11 11.6 0.2 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS DUF4252 PF14060.6 EWM23838.1 - 1.4 8.8 4.3 2.3 8.1 0.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4252) MAT1 PF06391.13 EWM23839.1 - 3.3e-10 40.1 17.8 6.2e-10 39.3 17.8 1.4 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-RING_5 PF14634.6 EWM23839.1 - 1.1e-05 25.2 7.4 3.3e-05 23.8 7.5 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EWM23839.1 - 2.4e-05 24.3 2.1 4.7e-05 23.3 2.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EWM23839.1 - 0.00035 20.7 2.7 0.00035 20.7 2.7 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 EWM23839.1 - 0.00044 20.5 4.5 0.00082 19.7 4.5 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EWM23839.1 - 0.00065 19.5 1.7 0.0015 18.4 1.7 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EWM23839.1 - 0.0015 18.4 5.5 0.0043 16.9 5.6 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EWM23839.1 - 0.0031 17.3 6.4 0.007 16.2 6.4 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_5 PF17121.5 EWM23839.1 - 0.0043 16.9 2.0 0.0089 15.9 2.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CEBP_ZZ PF16366.5 EWM23839.1 - 0.0073 16.5 1.8 0.019 15.2 1.8 1.7 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain DUF2197 PF09963.9 EWM23839.1 - 0.019 15.2 3.6 0.038 14.3 3.6 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-rbx1 PF12678.7 EWM23839.1 - 0.038 14.3 2.5 0.078 13.3 2.5 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain FYVE PF01363.21 EWM23839.1 - 0.073 13.2 3.0 0.15 12.2 3.0 1.6 1 0 0 1 1 1 0 FYVE zinc finger Phage_cap_E PF03864.15 EWM23839.1 - 0.19 10.9 1.6 0.27 10.4 1.6 1.1 1 0 0 1 1 1 0 Phage major capsid protein E GP38 PF05268.11 EWM23839.1 - 0.85 9.2 9.6 1.2 8.7 9.6 1.2 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 HypA PF01155.19 EWM23839.1 - 3.6 7.6 6.8 58 3.8 6.8 2.4 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_4 PF14570.6 EWM23839.1 - 6 6.7 8.8 21 5.0 8.8 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain MAT1 PF06391.13 EWM23840.1 - 3.3e-10 40.1 17.8 5.5e-10 39.4 17.8 1.3 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 Phage_cap_E PF03864.15 EWM23840.1 - 0.18 11.0 1.6 0.24 10.5 1.6 1.1 1 0 0 1 1 1 0 Phage major capsid protein E DUF4472 PF14739.6 EWM23840.1 - 0.26 12.0 8.1 0.6 10.9 8.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) GP38 PF05268.11 EWM23840.1 - 0.77 9.4 9.6 1.1 8.9 9.6 1.2 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 FA_desaturase PF00487.24 EWM23841.1 - 4.5e-33 115.2 12.9 4.5e-33 115.2 12.9 1.7 2 0 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 EWM23841.1 - 1.1e-21 76.7 0.0 8.6e-21 73.9 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain GSHPx PF00255.19 EWM23842.1 - 3e-09 36.4 0.0 4.4e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase HEAT_2 PF13646.6 EWM23843.1 - 0.012 15.9 2.0 0.055 13.9 0.9 2.4 1 1 0 1 1 1 0 HEAT repeats HEAT PF02985.22 EWM23843.1 - 0.13 12.5 0.1 0.13 12.5 0.1 2.3 3 0 0 3 3 3 0 HEAT repeat Sec8_exocyst PF04048.14 EWM23844.1 - 0.033 14.1 0.0 0.054 13.4 0.0 1.4 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain Vault PF01505.18 EWM23844.1 - 0.048 13.8 0.1 0.1 12.8 0.1 1.6 1 1 0 1 1 1 0 Major Vault Protein repeat domain HEAT PF02985.22 EWM23846.1 - 3.5e-10 39.2 2.5 0.00027 20.9 0.1 3.7 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 EWM23846.1 - 1.8e-07 31.4 6.3 9.4e-05 22.7 0.7 2.9 1 1 2 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 EWM23846.1 - 0.00026 21.4 1.9 0.011 16.2 0.4 2.7 2 0 0 2 2 2 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EWM23846.1 - 0.14 12.8 0.0 0.24 12.0 0.0 1.5 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region DUF4487 PF14868.6 EWM23846.1 - 0.15 10.8 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4487) PPR_3 PF13812.6 EWM23848.1 - 1.9e-24 85.5 0.0 1.1e-06 28.6 0.0 5.2 3 1 3 6 6 6 5 Pentatricopeptide repeat domain PPR PF01535.20 EWM23848.1 - 2.6e-18 64.9 0.0 0.00051 20.1 0.0 6.0 6 0 0 6 6 6 3 PPR repeat PPR_2 PF13041.6 EWM23848.1 - 3.7e-17 62.2 0.0 3.2e-07 30.4 0.0 4.3 2 1 2 4 4 4 4 PPR repeat family PPR_1 PF12854.7 EWM23848.1 - 8.1e-14 51.0 0.1 0.00043 19.9 0.0 4.8 5 0 0 5 5 5 3 PPR repeat PPR_long PF17177.4 EWM23848.1 - 1.2e-09 37.8 0.2 2.1e-06 27.3 0.0 2.0 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 EWM23848.1 - 0.0012 19.5 4.7 1.7 9.7 0.1 4.8 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 EWM23848.1 - 0.017 15.7 7.8 0.12 13.1 1.0 4.0 4 1 1 5 5 5 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 EWM23848.1 - 0.034 14.1 0.1 5.1 7.0 0.0 2.5 1 1 1 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal B12-binding_2 PF02607.17 EWM23848.1 - 0.2 12.1 1.6 5.5 7.5 0.2 2.9 3 0 0 3 3 3 0 B12 binding domain GTP1_OBG PF01018.22 EWM23849.1 - 5.5e-22 78.0 4.6 7.4e-22 77.6 4.6 1.1 1 0 0 1 1 1 1 GTP1/OBG DUF572 PF04502.13 EWM23850.1 - 0.65 9.6 23.1 0.76 9.3 23.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) SAPS PF04499.15 EWM23850.1 - 4.2 6.0 9.1 5.1 5.8 9.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF3141 PF11339.8 EWM23850.1 - 6.2 5.1 5.1 0.37 9.2 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3141) PPR_3 PF13812.6 EWM23851.1 - 7e-11 42.0 0.0 2.5e-07 30.7 0.0 3.5 3 1 1 4 4 4 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 EWM23851.1 - 8e-07 29.2 0.0 0.00062 19.9 0.0 3.4 4 0 0 4 4 4 1 PPR repeat family PPR PF01535.20 EWM23851.1 - 6.2e-05 23.0 0.0 0.85 10.0 0.0 3.5 3 0 0 3 3 3 2 PPR repeat PPR_long PF17177.4 EWM23851.1 - 0.015 14.7 0.1 0.046 13.1 0.0 1.8 2 0 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EWM23851.1 - 0.02 14.6 0.0 0.51 10.1 0.0 2.7 3 0 0 3 3 3 0 PPR repeat EF1_GNE PF00736.19 EWM23852.1 - 7.6e-27 93.3 0.6 1.4e-26 92.5 0.6 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 EWM23852.1 - 0.013 15.9 0.5 0.031 14.7 0.1 1.9 1 1 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Ribosomal_60s PF00428.19 EWM23852.1 - 0.048 14.2 0.3 0.048 14.2 0.3 2.9 3 1 0 3 3 3 0 60s Acidic ribosomal protein RNF220 PF15926.5 EWM23852.1 - 0.052 13.2 0.3 0.069 12.8 0.3 1.2 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 UBA2_C PF16195.5 EWM23852.1 - 0.09 13.5 7.0 0.14 12.9 7.0 1.3 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus Stm1_N PF09598.10 EWM23852.1 - 0.096 13.5 1.0 0.096 13.5 1.0 2.1 2 0 0 2 2 2 0 Stm1 TRPM_tetra PF16519.5 EWM23852.1 - 4.2 7.6 5.5 0.8 9.9 0.8 2.0 2 0 0 2 2 2 0 Tetramerisation domain of TRPM Nepo_coat PF03391.15 EWM23853.1 - 0.032 13.7 0.1 0.081 12.4 0.1 1.7 2 0 0 2 2 2 0 Nepovirus coat protein, central domain ChapFlgA_N PF17656.1 EWM23853.1 - 0.054 13.7 0.4 4.5 7.5 0.0 2.5 2 0 0 2 2 2 0 FlgA N-terminal domain Glyco_hydro_17 PF00332.18 EWM23854.1 - 8.5e-27 94.5 0.0 1.3e-26 94.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 ATG13 PF10033.9 EWM23855.1 - 1.5e-19 70.7 0.0 4.6e-19 69.1 0.0 1.7 1 1 0 1 1 1 1 Autophagy-related protein 13 His_biosynth PF00977.21 EWM23856.1 - 0.0088 15.5 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein NAD_binding_1 PF00175.21 EWM23857.1 - 5.3e-29 101.1 0.0 1.1e-28 100.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EWM23857.1 - 0.0011 19.3 0.0 0.0024 18.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NADPH_Ox PF08414.10 EWM23857.1 - 0.068 13.5 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Respiratory burst NADPH oxidase 7TM_GPCR_Srz PF10325.9 EWM23857.1 - 0.22 10.8 0.2 0.32 10.3 0.2 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srz His_biosynth PF00977.21 EWM23859.1 - 2.2e-10 40.4 0.0 3e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Aldolase PF01081.19 EWM23859.1 - 0.016 14.6 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 KDPG and KHG aldolase Ribul_P_3_epim PF00834.19 EWM23859.1 - 0.026 13.9 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family TMP-TENI PF02581.17 EWM23859.1 - 0.04 13.3 0.1 0.05 12.9 0.1 1.4 1 1 0 1 1 1 0 Thiamine monophosphate synthase PH PF00169.29 EWM23861.1 - 8.8e-06 26.2 0.0 5e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 EWM23861.1 - 0.0064 16.9 0.0 0.071 13.5 0.0 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 EWM23861.1 - 0.04 14.3 0.0 0.071 13.5 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain HORMA PF02301.18 EWM23863.1 - 1.7e-05 24.5 0.0 2.2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 HORMA domain Aldo_ket_red PF00248.21 EWM23864.1 - 2e-24 86.3 0.0 2.4e-21 76.2 0.0 2.3 2 0 0 2 2 2 2 Aldo/keto reductase family Mob1_phocein PF03637.17 EWM23866.1 - 1.2e-57 194.6 0.1 1.6e-57 194.2 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family Mob1_phocein PF03637.17 EWM23867.1 - 1.2e-57 194.6 0.1 1.6e-57 194.2 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family SIR2 PF02146.17 EWM23868.1 - 6.7e-44 149.9 0.0 1.6e-43 148.6 0.0 1.6 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 EWM23868.1 - 0.00018 21.3 0.0 0.031 14.0 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain PNTB PF02233.16 EWM23868.1 - 0.025 13.5 0.2 0.14 11.1 0.0 1.9 2 0 0 2 2 2 0 NAD(P) transhydrogenase beta subunit ABC_tran PF00005.27 EWM23869.1 - 3.8e-38 131.1 0.0 6.4e-19 68.8 0.0 2.3 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 EWM23869.1 - 2.9e-13 49.4 8.1 7.2e-13 48.1 8.1 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.6 EWM23869.1 - 4.8e-10 39.7 0.2 0.01 15.6 0.5 4.2 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EWM23869.1 - 1e-09 38.2 0.1 0.0062 16.0 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.27 EWM23869.1 - 5.7e-08 32.3 2.5 5.7e-08 32.3 2.5 2.6 3 0 0 3 3 2 1 4Fe-4S binding domain AAA_22 PF13401.6 EWM23869.1 - 9.2e-07 29.2 0.0 0.0033 17.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EWM23869.1 - 1.1e-06 29.1 0.0 0.022 15.2 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 EWM23869.1 - 4.3e-06 27.2 0.0 0.14 12.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Fer4_6 PF12837.7 EWM23869.1 - 6.6e-06 26.0 12.2 6.1e-05 22.9 1.4 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain AAA_23 PF13476.6 EWM23869.1 - 1.2e-05 25.9 0.0 0.035 14.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EWM23869.1 - 4.5e-05 23.1 0.1 0.09 12.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.12 EWM23869.1 - 4.7e-05 23.4 1.0 0.014 15.4 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_5 PF07728.14 EWM23869.1 - 5.2e-05 23.3 0.0 0.046 13.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 EWM23869.1 - 8.3e-05 22.6 0.1 0.28 11.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 EWM23869.1 - 9.7e-05 22.2 0.3 0.27 10.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EWM23869.1 - 0.00013 22.1 0.0 0.12 12.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 EWM23869.1 - 0.00014 21.5 0.9 0.032 13.9 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_15 PF13175.6 EWM23869.1 - 0.00017 21.4 0.0 0.75 9.4 0.0 2.6 3 0 0 3 3 2 2 AAA ATPase domain RNA_helicase PF00910.22 EWM23869.1 - 0.00044 20.6 0.0 0.78 10.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Thymidylate_kin PF02223.17 EWM23869.1 - 0.00052 19.7 0.0 0.55 9.9 0.0 2.5 2 0 0 2 2 2 1 Thymidylate kinase Fer4_2 PF12797.7 EWM23869.1 - 0.00067 19.6 0.5 0.00067 19.6 0.5 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Rad17 PF03215.15 EWM23869.1 - 0.00073 19.5 0.0 0.061 13.2 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain TsaE PF02367.17 EWM23869.1 - 0.00079 19.4 0.0 0.049 13.6 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fer4_21 PF14697.6 EWM23869.1 - 0.00094 19.3 11.7 0.0023 18.0 11.7 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_24 PF13479.6 EWM23869.1 - 0.0012 18.6 0.1 0.42 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4_7 PF12838.7 EWM23869.1 - 0.0039 17.7 1.5 0.0039 17.7 1.5 2.5 1 1 2 3 3 3 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 EWM23869.1 - 0.0041 17.3 12.1 0.0083 16.3 12.1 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 EWM23869.1 - 0.0043 17.1 1.1 0.0043 17.1 1.1 2.4 1 1 1 2 2 2 1 4Fe-4S dicluster domain AAA_7 PF12775.7 EWM23869.1 - 0.0083 15.7 0.0 2.2 7.8 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 EWM23869.1 - 0.017 14.4 0.1 3.3 7.0 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin VirE PF05272.11 EWM23869.1 - 0.024 14.4 0.0 9.2 5.9 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E AAA_13 PF13166.6 EWM23869.1 - 0.027 13.2 0.1 0.33 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EWM23869.1 - 0.027 13.7 0.0 1.8 7.7 0.0 2.5 3 0 0 3 3 2 0 NB-ARC domain AAA_28 PF13521.6 EWM23869.1 - 0.032 14.5 0.1 3.6 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EWM23869.1 - 0.041 14.0 0.1 11 6.2 0.0 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.6 EWM23869.1 - 0.043 14.4 0.0 5.5 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EWM23869.1 - 0.048 13.6 1.0 2.4 8.0 0.0 2.8 2 0 0 2 2 2 0 NTPase DUF815 PF05673.13 EWM23869.1 - 0.06 12.5 0.1 9.3 5.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 EWM23869.1 - 0.076 12.6 0.0 10 5.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain CLP1_P PF16575.5 EWM23869.1 - 0.082 12.7 0.5 2.9 7.6 0.0 2.4 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Roc PF08477.13 EWM23869.1 - 0.12 12.6 0.4 1.7 8.9 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MobB PF03205.14 EWM23869.1 - 0.12 12.3 0.3 5 7.0 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.6 EWM23869.1 - 0.13 12.3 0.0 21 5.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EWM23869.1 - 0.15 12.4 0.2 4.3 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EWM23869.1 - 0.2 11.1 0.2 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein KAP_NTPase PF07693.14 EWM23869.1 - 0.2 10.9 0.0 13 4.9 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain Fer4_16 PF13484.6 EWM23869.1 - 1.2 10.1 11.4 0.079 13.9 2.0 2.7 2 1 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_8 PF13183.6 EWM23869.1 - 3.3 8.2 11.5 0.48 10.9 1.7 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 EWM23869.1 - 3.4 8.4 15.3 0.16 12.6 3.0 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain ABC_tran PF00005.27 EWM23870.1 - 1.3e-27 97.0 0.0 2.3e-16 60.5 0.0 2.3 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 EWM23870.1 - 2.2e-13 49.8 8.1 5.4e-13 48.5 8.1 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.6 EWM23870.1 - 1.2e-08 35.1 0.4 0.0082 16.0 0.5 3.1 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Fer4 PF00037.27 EWM23870.1 - 4.3e-08 32.6 2.5 4.3e-08 32.6 2.5 2.7 3 0 0 3 3 2 1 4Fe-4S binding domain AAA_16 PF13191.6 EWM23870.1 - 1.1e-06 29.2 0.0 0.029 14.7 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 EWM23870.1 - 2.8e-06 27.8 0.0 0.11 13.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Fer4_6 PF12837.7 EWM23870.1 - 4e-06 26.7 12.2 4.6e-05 23.3 1.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain AAA_23 PF13476.6 EWM23870.1 - 7.9e-06 26.5 0.0 0.026 15.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EWM23870.1 - 9e-06 26.0 0.1 0.036 14.4 0.0 2.5 2 1 0 2 2 2 2 AAA domain NACHT PF05729.12 EWM23870.1 - 2.2e-05 24.4 0.7 0.01 15.8 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.6 EWM23870.1 - 2.7e-05 23.8 0.1 0.067 12.9 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EWM23870.1 - 5.7e-05 23.1 0.1 0.2 11.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_5 PF07728.14 EWM23870.1 - 6e-05 23.1 0.1 0.034 14.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EWM23870.1 - 7.8e-05 22.5 0.4 0.21 11.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EWM23870.1 - 8.4e-05 22.8 0.0 0.091 12.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 EWM23870.1 - 8.6e-05 22.3 0.9 0.024 14.3 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SMC_N PF02463.19 EWM23870.1 - 0.0001 21.8 0.0 2.2 7.7 0.0 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EWM23870.1 - 0.00017 21.5 0.0 0.56 9.9 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain RNA_helicase PF00910.22 EWM23870.1 - 0.00025 21.4 0.0 0.59 10.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Thymidylate_kin PF02223.17 EWM23870.1 - 0.00038 20.2 0.0 0.4 10.3 0.0 2.3 2 0 0 2 2 2 2 Thymidylate kinase Rad17 PF03215.15 EWM23870.1 - 0.00043 20.2 0.0 0.044 13.7 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain TsaE PF02367.17 EWM23870.1 - 0.00047 20.1 0.0 0.036 14.1 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fer4_2 PF12797.7 EWM23870.1 - 0.00051 20.0 0.5 0.00051 20.0 0.5 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_24 PF13479.6 EWM23870.1 - 0.0007 19.4 0.1 0.32 10.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4_7 PF12838.7 EWM23870.1 - 0.00078 20.0 7.7 0.0012 19.4 0.4 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 EWM23870.1 - 0.00085 19.4 11.7 0.0016 18.5 11.7 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 EWM23870.1 - 0.0014 18.7 11.1 0.0028 17.8 11.1 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 EWM23870.1 - 0.0037 17.3 1.2 0.0037 17.3 1.2 2.4 1 1 1 2 2 2 1 4Fe-4S dicluster domain AAA_7 PF12775.7 EWM23870.1 - 0.0052 16.3 0.0 1.6 8.2 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 EWM23870.1 - 0.013 14.8 0.1 2.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin VirE PF05272.11 EWM23870.1 - 0.015 15.0 0.0 6.8 6.4 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E AAA_13 PF13166.6 EWM23870.1 - 0.017 13.8 0.1 0.25 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EWM23870.1 - 0.019 15.2 0.1 2.7 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EWM23870.1 - 0.02 14.1 0.0 1.3 8.2 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.6 EWM23870.1 - 0.03 14.9 0.0 3.9 8.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EWM23870.1 - 0.035 14.0 1.0 1.8 8.4 0.0 2.6 2 0 0 2 2 2 0 NTPase DUF815 PF05673.13 EWM23870.1 - 0.036 13.2 0.1 7 5.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 EWM23870.1 - 0.036 14.1 0.0 7.7 6.6 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_25 PF13481.6 EWM23870.1 - 0.045 13.3 0.0 7.4 6.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain CLP1_P PF16575.5 EWM23870.1 - 0.048 13.4 0.4 2.2 8.0 0.0 2.4 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Fer4_16 PF13484.6 EWM23870.1 - 0.055 14.4 1.8 0.055 14.4 1.8 2.7 2 1 0 2 2 2 0 4Fe-4S double cluster binding domain Roc PF08477.13 EWM23870.1 - 0.07 13.4 0.3 1.3 9.3 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MobB PF03205.14 EWM23870.1 - 0.073 13.0 0.3 3.7 7.4 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.6 EWM23870.1 - 0.092 13.1 0.2 3.2 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EWM23870.1 - 0.097 12.7 0.0 16 5.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EWM23870.1 - 0.12 11.8 0.1 0.81 9.1 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.21 EWM23870.1 - 0.13 11.6 0.3 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI KAP_NTPase PF07693.14 EWM23870.1 - 0.14 11.3 0.0 8.9 5.4 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain Sigma54_activat PF00158.26 EWM23870.1 - 0.14 11.8 0.1 1.4 8.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Septin PF00735.18 EWM23870.1 - 0.15 11.4 0.0 2.1 7.6 0.0 2.1 2 0 0 2 2 2 0 Septin ATPase PF06745.13 EWM23870.1 - 0.2 11.0 0.2 1.4 8.2 0.0 2.0 2 0 0 2 2 2 0 KaiC MeaB PF03308.16 EWM23870.1 - 0.21 10.5 0.4 2 7.3 0.0 2.4 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Fer4_4 PF12800.7 EWM23870.1 - 2.1 9.1 15.3 0.12 12.9 3.0 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.6 EWM23870.1 - 3.2 8.3 12.2 0.42 11.1 1.9 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 EWM23870.1 - 7.2 7.2 12.8 0.1 13.2 1.5 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain DUF155 PF02582.14 EWM23871.1 - 2.3e-18 66.9 0.0 3.1e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Hs1pro-1_N PF07231.12 EWM23873.1 - 2.9e-08 33.7 0.0 5.2e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Hs1pro-1 N-terminus DUF1681 PF07933.14 EWM23874.1 - 2.8e-50 169.9 0.0 3.7e-50 169.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) PP2C PF00481.21 EWM23875.1 - 1.2e-45 156.2 0.0 4.4e-25 88.8 0.0 2.3 2 1 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EWM23875.1 - 0.00012 21.8 0.0 0.00036 20.3 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 EWM23876.1 - 0.04 13.6 0.0 0.049 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein phosphatase 2C PP2C PF00481.21 EWM23877.1 - 3.4e-15 56.4 0.0 4.4e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EWM23877.1 - 0.0045 16.9 0.0 0.006 16.5 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Ribosomal_L29 PF00831.23 EWM23878.1 - 3.4e-20 71.8 2.9 3.4e-20 71.8 2.9 2.1 2 1 0 2 2 2 1 Ribosomal L29 protein TolA_bind_tri PF16331.5 EWM23878.1 - 0.028 14.5 0.1 0.062 13.4 0.1 1.6 1 0 0 1 1 1 0 TolA binding protein trimerisation Prefoldin PF02996.17 EWM23878.1 - 1.1 9.1 7.9 2.4 8.1 2.8 2.5 2 1 1 3 3 3 0 Prefoldin subunit Snapin_Pallidin PF14712.6 EWM23878.1 - 1.7 9.1 7.8 1 9.8 3.0 2.1 1 1 1 2 2 2 0 Snapin/Pallidin DUF1127 PF06568.11 EWM23880.1 - 0.13 12.0 11.0 0.3 10.9 11.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) zf-TFIIIC PF12660.7 EWM23882.1 - 1.7e-06 27.9 0.4 4.1e-06 26.7 0.4 1.7 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex PHF5 PF03660.14 EWM23882.1 - 1.3 9.3 5.0 0.44 10.8 1.7 1.9 2 1 1 3 3 3 0 PHF5-like protein DUF1713 PF08213.11 EWM23883.1 - 2.2e-08 33.9 20.2 3.5e-08 33.2 20.2 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Pep3_Vps18 PF05131.14 EWM23884.1 - 6.8e-11 42.2 0.0 1.7e-10 40.9 0.0 1.7 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Vps39_2 PF10367.9 EWM23884.1 - 0.0011 19.4 0.1 0.0025 18.2 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.6 EWM23884.1 - 0.011 16.0 2.4 0.011 16.0 2.4 2.0 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.6 EWM23884.1 - 0.064 13.2 4.8 0.092 12.7 2.8 2.1 2 0 0 2 2 2 0 zinc-RING finger domain CCG PF02754.16 EWM23884.1 - 0.17 12.2 0.1 0.35 11.1 0.1 1.6 1 0 0 1 1 1 0 Cysteine-rich domain Zn_ribbon_17 PF17120.5 EWM23884.1 - 0.19 11.4 3.5 0.42 10.3 3.5 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF2175 PF09943.9 EWM23884.1 - 0.19 12.1 0.0 0.46 10.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) zf-RING_UBOX PF13445.6 EWM23884.1 - 0.3 11.1 1.7 0.79 9.8 1.7 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_11 PF17123.5 EWM23884.1 - 0.68 9.7 6.1 1.4 8.7 6.1 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 EWM23884.1 - 1.7 9.0 3.9 5.7 7.3 3.9 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EWM23884.1 - 2 8.4 8.4 0.29 11.0 3.8 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EWM23884.1 - 7.3 6.6 7.3 0.56 10.1 2.4 1.7 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) Sugar_tr PF00083.24 EWM23885.1 - 5.5e-27 94.7 15.2 1.9e-16 60.0 5.4 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EWM23885.1 - 1.5e-24 86.6 31.7 1.8e-20 73.2 16.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EWM23885.1 - 0.00088 18.7 3.4 0.00088 18.7 3.4 1.9 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB DUF4131 PF13567.6 EWM23885.1 - 0.0037 16.9 3.8 1.1 8.9 0.2 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF4131) DUF2157 PF09925.9 EWM23885.1 - 0.91 9.3 10.6 11 5.8 8.7 3.0 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) Zip PF02535.22 EWM23886.1 - 1.2e-11 44.5 6.8 1.2e-11 44.5 6.8 3.1 2 1 1 3 3 3 2 ZIP Zinc transporter BAGE PF08180.11 EWM23886.1 - 0.15 12.1 2.6 0.58 10.3 2.6 2.0 1 0 0 1 1 1 0 B melanoma antigen family DUF2061 PF09834.9 EWM23887.1 - 3.9e-24 84.9 5.9 3.7e-12 46.6 2.2 2.3 2 0 0 2 2 2 2 Predicted membrane protein (DUF2061) PHM7_cyt PF14703.6 EWM23887.1 - 0.017 15.4 0.0 0.031 14.5 0.0 1.3 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter La PF05383.17 EWM23888.1 - 6.3e-20 71.0 0.0 1e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 La domain Elf4 PF07011.11 EWM23889.1 - 3.4e-08 33.3 0.7 0.0046 16.8 0.0 2.2 2 0 0 2 2 2 2 Early Flowering 4 domain DUF4611 PF15387.6 EWM23889.1 - 0.017 15.4 1.9 0.031 14.5 1.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) SSXT PF05030.12 EWM23889.1 - 0.26 10.9 7.2 1.4 8.6 7.2 2.0 1 1 0 1 1 1 0 SSXT protein (N-terminal region) ENTH PF01417.20 EWM23890.1 - 1.7e-23 83.0 0.0 2.5e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 ENTH domain VHS PF00790.19 EWM23890.1 - 0.013 15.3 0.0 0.029 14.2 0.0 1.6 1 1 0 1 1 1 0 VHS domain Asp2 PF16929.5 EWM23890.1 - 0.023 13.7 0.2 0.029 13.4 0.2 1.1 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter LRR_10 PF18805.1 EWM23890.1 - 0.029 14.0 0.2 0.19 11.4 0.1 2.1 2 0 0 2 2 2 0 Leucine-rich repeat ANTH PF07651.16 EWM23890.1 - 0.1 11.6 0.1 0.2 10.6 0.0 1.6 1 1 0 1 1 1 0 ANTH domain DUF501 PF04417.12 EWM23891.1 - 5.4e-30 104.0 0.6 2.7e-29 101.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF501) DASH_Dad1 PF08649.10 EWM23891.1 - 0.14 12.3 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 DASH complex subunit Dad1 Amino_oxidase PF01593.24 EWM23892.1 - 1e-74 252.5 0.0 1.3e-74 252.1 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EWM23892.1 - 6.5e-15 55.1 0.0 1.6e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EWM23892.1 - 1.1e-05 25.3 0.1 0.00016 21.4 0.1 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase MCRA PF06100.11 EWM23892.1 - 0.00047 19.1 0.0 0.022 13.5 0.0 2.1 2 0 0 2 2 2 1 MCRA family Thi4 PF01946.17 EWM23892.1 - 0.00065 19.0 0.0 0.0013 18.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 EWM23892.1 - 0.0016 17.7 0.1 0.0027 17.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 EWM23892.1 - 0.0029 16.7 0.3 0.0076 15.4 0.5 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 EWM23892.1 - 0.0091 16.5 0.0 0.5 11.0 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EWM23892.1 - 0.015 14.5 0.1 0.05 12.8 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EWM23892.1 - 0.023 14.1 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_7 PF03441.14 EWM23893.1 - 2.4e-75 252.5 0.3 3.5e-75 251.9 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EWM23893.1 - 1.1e-44 152.3 0.0 2e-44 151.5 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase Sugar_tr PF00083.24 EWM23895.1 - 2.7e-38 132.0 23.2 1.7e-24 86.5 8.5 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EWM23895.1 - 3.5e-21 75.5 31.2 4.7e-19 68.5 29.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ring_hydroxyl_A PF00848.19 EWM23896.1 - 7.4e-25 88.2 0.0 1.1e-24 87.6 0.0 1.2 1 0 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 EWM23896.1 - 4.6e-17 61.7 0.0 9.4e-17 60.7 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain TAFII55_N PF04658.13 EWM23896.1 - 0.085 12.6 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 TAFII55 protein conserved region Ribosomal_S13 PF00416.22 EWM23897.1 - 9.2e-50 168.3 1.9 1.2e-49 167.9 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 EWM23897.1 - 0.019 13.7 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Glyoxalase PF00903.25 EWM23898.1 - 6.3e-09 36.1 0.0 0.00079 19.6 0.0 2.8 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EWM23898.1 - 2.5e-07 30.9 0.0 0.00073 19.8 0.0 2.8 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 EWM23898.1 - 1.3e-05 25.4 0.0 8.1e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 EWM23898.1 - 0.0059 16.7 0.1 1.6 8.8 0.0 3.5 3 1 0 3 3 3 1 Glyoxalase-like domain Lysine_decarbox PF03641.14 EWM23899.1 - 2.2e-19 69.9 0.0 3.1e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 EWM23899.1 - 1.8e-15 56.9 0.1 2.6e-15 56.4 0.1 1.3 1 0 0 1 1 1 1 SLOG cluster4 family OB_NTP_bind PF07717.16 EWM23901.1 - 2.4e-16 59.9 0.0 5.1e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EWM23901.1 - 4.2e-11 43.2 0.0 8.3e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 EWM23901.1 - 6.3e-11 42.5 0.0 1.6e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) AAA_22 PF13401.6 EWM23901.1 - 3.6e-05 24.0 0.1 0.00021 21.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EWM23901.1 - 0.00011 22.0 1.6 0.0014 18.4 0.7 2.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase Flavi_DEAD PF07652.14 EWM23901.1 - 0.0039 17.2 0.0 0.0091 16.0 0.0 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain FtsK_SpoIIIE PF01580.18 EWM23901.1 - 0.048 13.0 0.0 0.093 12.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.27 EWM23901.1 - 0.057 13.9 0.0 0.2 12.2 0.0 2.0 1 1 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 EWM23901.1 - 0.058 13.1 0.1 0.15 11.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EWM23901.1 - 0.068 12.7 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 EWM23901.1 - 0.07 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.6 EWM23901.1 - 0.073 13.4 0.2 0.39 11.0 0.1 2.3 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 EWM23901.1 - 0.12 11.4 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Mago_nashi PF02792.14 EWM23902.1 - 7.3e-73 243.3 0.2 8.2e-73 243.2 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein RRM_1 PF00076.22 EWM23903.1 - 4.8e-14 51.9 0.0 7.7e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FabA PF07977.13 EWM23904.1 - 6e-37 126.3 0.1 7.7e-37 126.0 0.1 1.1 1 0 0 1 1 1 1 FabA-like domain MaoC_dehydratas PF01575.19 EWM23904.1 - 0.0013 18.2 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain 4HBT PF03061.22 EWM23904.1 - 0.071 13.5 0.0 0.14 12.5 0.0 1.5 1 1 0 1 1 1 0 Thioesterase superfamily Img2 PF05046.14 EWM23904.1 - 0.14 12.4 0.0 0.53 10.6 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) FBPase PF00316.20 EWM23906.1 - 8.3e-32 110.2 0.0 1.2e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain CRAL_TRIO PF00650.20 EWM23907.1 - 2e-27 95.9 0.0 2.5e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EWM23907.1 - 7.3e-05 22.9 0.0 0.00013 22.2 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Sugar_tr PF00083.24 EWM23908.1 - 1.9e-42 145.7 22.8 1.6e-27 96.5 9.1 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EWM23908.1 - 1.3e-37 129.6 38.1 5.1e-31 107.9 26.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.16 EWM23908.1 - 1.5e-05 23.5 0.5 3.2e-05 22.4 0.5 1.5 1 0 0 1 1 1 1 BT1 family TRI12 PF06609.13 EWM23908.1 - 0.00072 18.1 2.1 0.0056 15.1 0.5 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 EWM23908.1 - 0.0015 17.2 25.5 0.028 13.0 6.2 2.8 1 1 2 3 3 3 3 MFS/sugar transport protein DUF4131 PF13567.6 EWM23908.1 - 0.25 11.0 11.1 0.84 9.3 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) KH_1 PF00013.29 EWM23909.1 - 6.3e-39 131.6 2.3 1e-12 47.7 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EWM23909.1 - 2.1e-08 33.9 5.7 0.0076 16.1 0.6 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EWM23909.1 - 1.5e-06 28.0 2.0 0.031 14.1 0.3 3.9 3 1 1 4 4 4 2 KH domain KH_5 PF13184.6 EWM23909.1 - 0.34 11.0 1.4 12 6.0 0.0 3.0 3 0 0 3 3 3 0 NusA-like KH domain DUF4953 PF16313.5 EWM23910.1 - 6.6e-57 193.1 0.0 9.5e-57 192.6 0.0 1.2 1 0 0 1 1 1 1 Met-zincin DUF5117 PF17148.4 EWM23910.1 - 2.8e-10 40.4 0.0 2e-09 37.6 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5117) Reprolysin_5 PF13688.6 EWM23910.1 - 0.0076 16.4 0.1 0.0076 16.4 0.1 1.7 2 0 0 2 2 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 EWM23910.1 - 0.015 15.0 0.1 0.015 15.0 0.1 2.0 3 0 0 3 3 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 EWM23910.1 - 0.019 15.5 0.1 0.041 14.4 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EWM23910.1 - 0.019 14.8 0.5 0.019 14.8 0.5 1.6 1 1 0 1 1 1 0 Matrixin Peptidase_M43 PF05572.13 EWM23910.1 - 0.026 14.4 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Astacin PF01400.24 EWM23910.1 - 0.04 13.5 0.3 1.6 8.3 0.2 2.3 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Peptidase_M57 PF12388.8 EWM23910.1 - 0.051 13.2 0.3 0.089 12.4 0.3 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Zincin_1 PF06262.11 EWM23910.1 - 0.076 13.1 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 Zincin-like metallopeptidase Reprolysin_2 PF13574.6 EWM23910.1 - 0.12 12.3 0.1 0.12 12.3 0.1 2.1 2 0 0 2 2 1 0 Metallo-peptidase family M12B Reprolysin-like Polyketide_cyc PF03364.20 EWM23911.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Fe_bilin_red PF05996.12 EWM23912.1 - 3e-53 180.8 0.1 3.9e-53 180.5 0.1 1.1 1 0 0 1 1 1 1 Ferredoxin-dependent bilin reductase Pribosyltran PF00156.27 EWM23913.1 - 1.3e-16 60.5 0.0 1.8e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EWM23913.1 - 0.00014 21.4 0.0 0.00018 21.0 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase ATP-synt_ab PF00006.25 EWM23914.1 - 9.8e-67 224.7 0.0 1.3e-66 224.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EWM23914.1 - 1.7e-11 44.5 0.5 3.5e-11 43.5 0.5 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain APC_rep PF18797.1 EWM23914.1 - 0.13 13.2 0.0 0.28 12.1 0.0 1.4 1 0 0 1 1 1 0 Adenomatous polyposis coli (APC) repeat Metallophos PF00149.28 EWM23915.1 - 1.1e-32 114.2 0.1 1.4e-32 113.9 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EWM23915.1 - 1.5e-19 70.2 0.2 2.5e-19 69.4 0.2 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Rubis-subs-bind PF09273.11 EWM23916.1 - 3.2e-11 44.0 0.4 9.2e-11 42.5 0.4 1.8 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 EWM23916.1 - 1.2e-07 32.2 0.0 2.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 SET domain DUF3727 PF12527.8 EWM23917.1 - 6.1e-07 29.6 9.5 0.00017 21.7 0.1 3.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3727) DUF1275 PF06912.11 EWM23918.1 - 6.3e-21 75.2 19.3 8.1e-21 74.8 19.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Mem_trans PF03547.18 EWM23919.1 - 3.2e-11 42.3 15.8 1.3e-07 30.4 1.6 2.1 2 0 0 2 2 2 2 Membrane transport protein Mem_trans PF03547.18 EWM23920.1 - 3.6e-11 42.1 15.8 1.4e-07 30.3 1.6 2.1 2 0 0 2 2 2 2 Membrane transport protein HECT PF00632.25 EWM23921.1 - 2.1e-64 217.9 0.0 2.8e-64 217.5 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Frankia_peptide PF14407.6 EWM23921.1 - 0.25 11.3 2.5 1.1 9.2 0.8 2.6 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. DHDPS PF00701.22 EWM23922.1 - 7.9e-88 293.9 0.0 1e-87 293.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PIG-H PF10181.9 EWM23923.1 - 6.4e-16 58.0 0.2 1.2e-15 57.1 0.2 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Aldo_ket_red PF00248.21 EWM23924.1 - 8.6e-18 64.5 0.0 2.1e-17 63.3 0.0 1.6 2 0 0 2 2 2 1 Aldo/keto reductase family EF-hand_7 PF13499.6 EWM23924.1 - 0.19 12.2 0.0 0.41 11.1 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair LANC_like PF05147.13 EWM23925.1 - 2.3e-58 197.5 0.0 2.9e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein C5-epim_C PF06662.13 EWM23925.1 - 0.076 12.5 0.1 0.33 10.4 0.1 1.8 1 1 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus TPR_MLP1_2 PF07926.12 EWM23926.1 - 0.001 19.1 0.6 0.0016 18.5 0.6 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Solute_trans_a PF03619.16 EWM23927.1 - 4.1e-90 301.9 12.4 4.8e-90 301.7 12.4 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF4407 PF14362.6 EWM23927.1 - 0.44 9.8 1.9 0.71 9.2 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Phtf-FEM1B_bdg PF12129.8 EWM23927.1 - 0.89 9.4 3.4 0.65 9.8 0.3 2.1 1 1 1 2 2 2 0 Male germ-cell putative homeodomain transcription factor PDZ_6 PF17820.1 EWM23928.1 - 0.001 18.8 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EWM23928.1 - 0.084 13.2 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 PDZ domain PRK PF00485.18 EWM23929.1 - 4.8e-43 147.2 0.0 6.6e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EWM23929.1 - 1.1e-05 26.0 0.1 3.2e-05 24.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EWM23929.1 - 5.1e-05 23.5 0.0 8.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EWM23929.1 - 0.00038 20.9 0.1 0.00092 19.6 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.6 EWM23929.1 - 0.0054 17.2 1.0 0.22 11.9 0.1 2.3 2 0 0 2 2 2 1 AAA domain Pox_A32 PF04665.12 EWM23929.1 - 0.013 14.9 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein Zeta_toxin PF06414.12 EWM23929.1 - 0.017 14.4 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 EWM23929.1 - 0.018 15.1 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP_bind_1 PF03029.17 EWM23929.1 - 0.02 14.7 0.2 0.039 13.7 0.0 1.5 2 0 0 2 2 1 0 Conserved hypothetical ATP binding protein Sigma54_activat PF00158.26 EWM23929.1 - 0.027 14.2 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 EWM23929.1 - 0.028 14.4 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 EWM23929.1 - 0.03 14.6 0.1 0.1 12.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EWM23929.1 - 0.036 14.6 0.0 0.068 13.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter CbiA PF01656.23 EWM23929.1 - 0.039 14.0 0.0 0.073 13.1 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Thymidylate_kin PF02223.17 EWM23929.1 - 0.043 13.5 0.1 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 Thymidylate kinase MobB PF03205.14 EWM23929.1 - 0.051 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATPase PF06745.13 EWM23929.1 - 0.057 12.8 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 KaiC T2SSE PF00437.20 EWM23929.1 - 0.066 12.3 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 EWM23929.1 - 0.084 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 EWM23929.1 - 0.095 12.4 0.4 6 6.5 0.0 2.1 1 1 0 2 2 2 0 Cytidylate kinase CobU PF02283.16 EWM23929.1 - 0.1 12.2 0.2 0.29 10.7 0.1 1.7 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase DUF692 PF05114.13 EWM23929.1 - 0.12 11.6 0.1 7.5 5.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF692) APS_kinase PF01583.20 EWM23929.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase CoaE PF01121.20 EWM23929.1 - 0.17 11.6 0.7 2.2 7.9 0.1 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase RNA_helicase PF00910.22 EWM23929.1 - 0.21 12.0 0.0 0.4 11.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase TIL PF01826.17 EWM23930.1 - 1.2 9.4 7.0 5.4 7.3 7.0 2.0 1 1 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain UCR_Fe-S_N PF10399.9 EWM23931.1 - 1.5 8.3 4.5 3 7.3 0.1 2.8 2 1 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal S1 PF00575.23 EWM23932.1 - 3.5e-66 219.5 21.3 7e-15 55.1 0.6 15.2 16 0 0 16 16 16 10 S1 RNA binding domain TPR_19 PF14559.6 EWM23932.1 - 3.8e-10 40.1 0.3 0.3 11.6 0.0 4.4 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 EWM23932.1 - 1.8e-07 31.4 8.1 0.27 12.2 0.1 6.6 3 1 4 7 7 7 1 Tetratricopeptide repeat PCB_OB PF17092.5 EWM23932.1 - 6e-05 23.8 1.6 11 6.9 0.0 7.2 7 2 0 7 7 7 1 Penicillin-binding protein OB-like domain Suf PF05843.14 EWM23932.1 - 0.0003 20.9 8.0 0.03 14.3 0.0 2.8 2 1 0 3 3 3 2 Suppressor of forked protein (Suf) NRDE-2 PF08424.10 EWM23932.1 - 0.0041 16.3 3.2 0.012 14.8 3.0 1.9 1 1 1 2 2 2 1 NRDE-2, necessary for RNA interference S1_2 PF13509.6 EWM23932.1 - 0.039 14.0 0.0 24 5.1 0.0 4.6 5 0 0 5 5 4 0 S1 domain PPR PF01535.20 EWM23932.1 - 0.096 13.0 0.3 28 5.3 0.0 3.4 2 0 0 2 2 2 0 PPR repeat SPACA9 PF15120.6 EWM23932.1 - 0.097 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 TPR_6 PF13174.6 EWM23932.1 - 0.29 11.9 2.0 16 6.4 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat RPN7 PF10602.9 EWM23932.1 - 0.45 10.2 3.0 11 5.6 0.1 3.1 2 1 1 3 3 3 0 26S proteasome subunit RPN7 TPR_15 PF13429.6 EWM23932.1 - 0.78 8.9 4.7 0.62 9.2 0.7 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EWM23932.1 - 1.5 8.8 4.4 66 3.6 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat FAD-oxidase_C PF02913.19 EWM23933.1 - 2.5e-59 200.9 0.1 3.5e-59 200.4 0.1 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EWM23933.1 - 8.2e-34 116.3 0.0 2.2e-33 115.0 0.0 1.8 1 0 0 1 1 1 1 FAD binding domain Methyltransf_16 PF10294.9 EWM23934.1 - 3.9e-10 39.7 0.0 2e-06 27.6 0.0 2.2 1 1 1 2 2 2 2 Lysine methyltransferase Cons_hypoth95 PF03602.15 EWM23934.1 - 0.057 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PS-DH PF14765.6 EWM23934.1 - 0.17 11.1 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Polyketide synthase dehydratase Paf67 PF10255.9 EWM23936.1 - 9.6e-91 304.8 0.0 1.6e-90 304.0 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_1 PF00515.28 EWM23936.1 - 0.032 14.1 0.0 0.15 11.9 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EWM23936.1 - 0.11 12.7 0.0 0.71 10.1 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat SUIM_assoc PF16619.5 EWM23936.1 - 0.51 10.4 7.4 1.5 9.0 7.4 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF2813 PF11398.8 EWM23936.1 - 1.1 8.4 6.1 3.2 6.9 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) Vps51 PF08700.11 EWM23937.1 - 2.4e-22 78.8 3.5 2.4e-22 78.8 3.5 2.1 2 0 0 2 2 2 1 Vps51/Vps67 Sec5 PF15469.6 EWM23937.1 - 1.1e-16 61.2 0.1 2.9e-16 59.8 0.1 1.7 1 0 0 1 1 1 1 Exocyst complex component Sec5 Dor1 PF04124.12 EWM23937.1 - 4.2e-11 42.1 2.9 7.3e-11 41.3 2.9 1.4 1 0 0 1 1 1 1 Dor1-like family Vps54_N PF10475.9 EWM23937.1 - 8.9e-07 28.5 4.0 1.6e-06 27.6 4.0 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 EWM23937.1 - 3.1e-05 24.1 6.6 6.7e-05 23.0 2.4 2.8 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Zw10 PF06248.13 EWM23937.1 - 0.013 14.1 0.5 0.023 13.3 0.5 1.3 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 LIF_OSM PF01291.17 EWM23937.1 - 0.025 14.7 0.2 0.064 13.4 0.2 1.6 1 0 0 1 1 1 0 LIF / OSM family CENP-F_leu_zip PF10473.9 EWM23937.1 - 0.057 13.4 2.4 0.17 11.9 2.4 1.8 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Vps53_N PF04100.12 EWM23937.1 - 0.06 12.3 1.2 0.13 11.2 1.2 1.5 1 0 0 1 1 1 0 Vps53-like, N-terminal COG5 PF10392.9 EWM23937.1 - 0.086 13.0 0.9 0.28 11.4 0.9 1.8 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF948 PF06103.11 EWM23937.1 - 0.13 12.6 3.4 0.78 10.0 0.4 3.4 3 1 1 4 4 3 0 Bacterial protein of unknown function (DUF948) WXG100 PF06013.12 EWM23937.1 - 0.14 12.4 2.8 6.2 7.1 0.1 3.7 3 0 0 3 3 3 0 Proteins of 100 residues with WXG PhoU PF01895.19 EWM23937.1 - 2.2 8.8 7.1 1.6 9.2 2.1 3.2 3 0 0 3 3 2 0 PhoU domain Hemerythrin PF01814.23 EWM23937.1 - 4.4 7.9 8.5 23 5.6 0.4 3.8 5 0 0 5 5 4 0 Hemerythrin HHE cation binding domain DUF1664 PF07889.12 EWM23937.1 - 4.5 7.3 5.5 5.7 7.0 3.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ABC_membrane PF00664.23 EWM23938.1 - 3.6e-56 190.8 3.9 6.3e-56 190.0 3.9 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EWM23938.1 - 1e-28 100.6 0.0 2.7e-28 99.2 0.0 1.8 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EWM23938.1 - 7.1e-06 25.6 0.0 8.4e-05 22.1 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EWM23938.1 - 0.00058 20.3 0.0 0.0035 17.8 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EWM23938.1 - 0.00097 19.4 0.0 0.004 17.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain ABC_membrane_3 PF13748.6 EWM23938.1 - 0.0047 16.2 3.1 0.02 14.2 3.1 2.0 1 1 0 1 1 1 1 ABC transporter transmembrane region Zeta_toxin PF06414.12 EWM23938.1 - 0.067 12.5 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Mucin PF01456.17 EWM23938.1 - 8.7 6.3 6.9 3.2 7.7 0.0 3.0 3 0 0 3 3 3 0 Mucin-like glycoprotein TAFII55_N PF04658.13 EWM23939.1 - 1.5e-21 76.8 0.0 9.3e-20 71.0 0.0 2.1 2 0 0 2 2 2 2 TAFII55 protein conserved region DEAD PF00270.29 EWM23940.1 - 1.6e-44 151.7 0.0 3.3e-44 150.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EWM23940.1 - 7.9e-21 74.5 0.0 6e-20 71.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EWM23940.1 - 4.9e-06 26.7 0.0 9.5e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Glyco_transf_90 PF05686.12 EWM23941.1 - 1.7e-19 70.0 1.5 1.4e-16 60.4 0.6 3.0 2 1 0 2 2 2 2 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 EWM23941.1 - 0.013 15.9 0.0 0.068 13.6 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferases group 1 LINES_N PF14694.6 EWM23942.1 - 5.8e-06 26.0 0.3 1.2e-05 25.0 0.3 1.4 1 0 0 1 1 1 1 Lines N-terminus LINES_C PF14695.6 EWM23942.1 - 0.00074 18.9 0.7 0.0017 17.8 0.1 2.0 2 0 0 2 2 2 1 Lines C-terminus DUF2267 PF10025.9 EWM23942.1 - 0.045 14.0 2.3 0.38 11.0 2.4 2.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) Bromodomain PF00439.25 EWM23943.1 - 2.2e-21 75.7 0.0 3.9e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Bromodomain APG6_N PF17675.1 EWM23943.1 - 0.0097 16.4 0.1 0.0097 16.4 0.1 4.0 3 1 0 3 3 3 1 Apg6 coiled-coil region DivIC PF04977.15 EWM23943.1 - 0.048 13.4 0.7 0.048 13.4 0.7 3.5 2 1 0 2 2 2 0 Septum formation initiator Borrelia_P83 PF05262.11 EWM23943.1 - 1.3 7.4 18.2 16 3.9 0.0 2.3 2 1 0 2 2 2 0 Borrelia P83/100 protein SF3b1 PF08920.10 EWM23944.1 - 4.5e-27 94.9 11.2 1.3e-25 90.1 0.2 3.7 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT PF02985.22 EWM23944.1 - 3.5e-13 48.6 6.3 0.28 11.6 0.0 8.5 10 0 0 10 10 10 4 HEAT repeat HEAT_EZ PF13513.6 EWM23944.1 - 1.1e-10 41.8 4.3 0.14 12.7 0.0 7.4 7 1 1 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.6 EWM23944.1 - 3e-09 37.2 14.4 0.021 15.2 0.1 8.1 5 2 4 10 10 10 3 HEAT repeats Adaptin_N PF01602.20 EWM23944.1 - 1.2e-07 30.7 0.0 0.00017 20.3 0.0 2.5 1 1 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 EWM23944.1 - 2.1e-05 24.6 8.7 0.73 9.9 0.0 6.4 5 1 1 7 7 7 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EWM23944.1 - 0.00017 21.2 2.2 0.096 12.2 0.0 3.2 4 0 0 4 4 4 2 CLASP N terminal NUC173 PF08161.12 EWM23944.1 - 0.00029 20.6 0.7 0.73 9.5 0.0 4.7 3 2 0 4 4 4 1 NUC173 domain Vac14_Fab1_bd PF12755.7 EWM23944.1 - 0.00036 21.1 2.6 1.5 9.5 0.0 5.2 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region Ecm29 PF13001.7 EWM23944.1 - 0.034 12.8 0.0 0.39 9.3 0.0 2.6 2 1 0 2 2 2 0 Proteasome stabiliser MMS19_C PF12460.8 EWM23944.1 - 0.047 12.8 0.0 28 3.7 0.0 3.9 4 1 0 4 4 4 0 RNAPII transcription regulator C-terminal DUF1428 PF07237.11 EWM23944.1 - 0.058 13.7 0.1 0.42 10.9 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1428) Arm PF00514.23 EWM23944.1 - 0.12 12.5 0.0 37 4.6 0.0 4.5 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DNA_pol_phi PF04931.13 EWM23944.1 - 0.29 9.2 2.7 6.1 4.8 0.0 2.8 3 0 0 3 3 3 0 DNA polymerase phi DFP PF04127.15 EWM23945.1 - 2.3e-19 70.0 0.0 1.1e-08 35.2 0.0 3.1 1 1 1 2 2 2 2 DNA / pantothenate metabolism flavoprotein Acyl-CoA_dh_N PF02771.16 EWM23946.1 - 7.2e-29 100.7 0.1 1.6e-28 99.6 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 EWM23946.1 - 2.5e-27 95.9 0.3 2.5e-27 95.9 0.3 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EWM23946.1 - 2.6e-21 75.6 0.0 4.2e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EWM23946.1 - 8.8e-06 26.0 0.0 1.5e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF4038 PF13204.6 EWM23947.1 - 0.035 13.7 0.0 0.035 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) CCT PF06203.14 EWM23952.1 - 2.7e-15 56.1 11.2 4.2e-15 55.5 11.2 1.3 1 0 0 1 1 1 1 CCT motif DUF3460 PF11943.8 EWM23952.1 - 0.16 12.2 1.0 0.33 11.2 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3460) Na_H_Exchanger PF00999.21 EWM23953.1 - 3.5e-55 187.4 37.1 5.1e-55 186.8 37.1 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Aminotran_1_2 PF00155.21 EWM23954.1 - 1.7e-58 198.5 0.0 2e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EWM23954.1 - 0.0026 16.6 0.0 0.0044 15.8 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Aminotran_3 PF00202.21 EWM23954.1 - 0.0049 15.6 0.0 0.0072 15.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Pro_isomerase PF00160.21 EWM23955.1 - 4.5e-48 163.5 0.0 5.1e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Complex1_LYR PF05347.15 EWM23956.1 - 2.3e-15 56.4 2.2 2.3e-15 56.4 2.2 1.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 EWM23956.1 - 1.9e-05 25.2 0.4 4.7e-05 23.9 0.4 1.7 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.6 EWM23956.1 - 0.014 16.1 1.2 0.028 15.2 1.2 1.5 1 0 0 1 1 1 0 Complex1_LYR-like DUF977 PF06163.11 EWM23956.1 - 0.064 13.2 0.2 0.22 11.4 0.1 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF977) Sdh5 PF03937.16 EWM23956.1 - 0.12 12.4 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase Chloroa_b-bind PF00504.21 EWM23957.1 - 1.1e-36 126.8 0.0 1.4e-36 126.4 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Dus PF01207.17 EWM23958.1 - 2.4e-66 224.0 0.0 3.8e-66 223.3 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 EWM23958.1 - 0.00013 21.3 0.1 0.031 13.5 0.0 2.5 2 1 0 2 2 2 1 Dihydroorotate dehydrogenase IMPDH PF00478.25 EWM23958.1 - 0.022 13.8 0.0 0.28 10.1 0.0 2.1 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 EWM23958.1 - 0.052 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein DUF2102 PF09875.9 EWM23959.1 - 0.036 13.8 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) DUF1244 PF06844.11 EWM23959.1 - 0.63 10.2 6.4 0.41 10.8 0.5 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1244) zf-GRF PF06839.12 EWM23960.1 - 4.5e-13 49.1 0.6 1.5e-12 47.4 0.6 2.0 1 0 0 1 1 1 1 GRF zinc finger Helicase_C PF00271.31 EWM23960.1 - 1e-11 45.2 0.0 8.3e-11 42.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EWM23960.1 - 3e-10 40.1 0.0 5.8e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SAP PF02037.27 EWM23960.1 - 2.7e-06 27.0 0.2 1e-05 25.2 0.2 2.1 1 0 0 1 1 1 1 SAP domain ResIII PF04851.15 EWM23960.1 - 0.00049 20.1 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Drc1-Sld2 PF11719.8 EWM23960.1 - 0.0072 15.9 0.3 0.02 14.4 0.3 1.8 1 0 0 1 1 1 1 DNA replication and checkpoint protein E1-E2_ATPase PF00122.20 EWM23961.1 - 8.8e-41 139.4 0.6 8.8e-41 139.4 0.6 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EWM23961.1 - 1.1e-37 129.5 2.8 1.1e-37 129.5 2.8 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EWM23961.1 - 1.3e-21 77.9 0.1 5.7e-16 59.4 0.0 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EWM23961.1 - 2e-15 56.6 0.0 4.7e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EWM23961.1 - 3.2e-15 55.6 0.4 1.2e-14 53.7 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EWM23961.1 - 2.7e-05 24.0 0.8 0.00077 19.3 0.7 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Serinc PF03348.15 EWM23961.1 - 0.05 12.5 0.6 0.11 11.4 0.6 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) HAD PF12710.7 EWM23961.1 - 0.11 12.8 0.0 0.71 10.2 0.0 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Proteasome PF00227.26 EWM23962.1 - 3.3e-23 82.2 0.0 5.4e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EWM23962.1 - 2.1e-05 24.1 0.0 4.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Arginase PF00491.21 EWM23963.1 - 4.3e-68 229.8 0.1 5.1e-68 229.6 0.1 1.0 1 0 0 1 1 1 1 Arginase family Ribosomal_L14e PF01929.17 EWM23964.1 - 8e-30 103.2 7.1 1.2e-29 102.6 7.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 EWM23964.1 - 0.066 13.2 0.5 0.13 12.3 0.5 1.6 1 1 0 1 1 1 0 KOW motif WD40 PF00400.32 EWM23965.1 - 1.4e-23 82.7 6.0 1.2e-05 25.9 0.9 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM23965.1 - 1.5e-13 50.8 0.0 0.00099 19.4 0.0 4.7 2 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Katanin_con80 PF13925.6 EWM23965.1 - 2.5e-13 50.4 0.0 4.5e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 con80 domain of Katanin eIF2A PF08662.11 EWM23965.1 - 0.15 12.0 0.0 1.7 8.5 0.0 2.1 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A DSS1_SEM1 PF05160.13 EWM23966.1 - 5.2e-16 58.4 22.7 7.2e-16 58.0 22.7 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family DUF2947 PF11163.8 EWM23966.1 - 0.0027 17.6 1.8 0.0032 17.3 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2947) DSS1_SEM1 PF05160.13 EWM23967.1 - 1.5e-05 25.0 7.3 2.3e-05 24.4 7.3 1.3 1 0 0 1 1 1 1 DSS1/SEM1 family PWWP PF00855.17 EWM23968.1 - 8.3e-13 48.6 0.3 2.1e-12 47.3 0.3 1.7 1 0 0 1 1 1 1 PWWP domain zf-HC5HC2H PF13771.6 EWM23968.1 - 0.00029 21.0 4.5 0.00029 21.0 4.5 3.1 3 0 0 3 3 3 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EWM23968.1 - 0.0062 16.7 0.5 0.0062 16.7 0.5 3.3 3 1 0 3 3 3 1 PHD-zinc-finger like domain Prok-RING_1 PF14446.6 EWM23968.1 - 0.094 12.7 6.8 0.49 10.4 0.3 3.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.29 EWM23968.1 - 8 6.5 31.5 0.072 13.0 1.1 3.7 4 1 0 4 4 4 0 PHD-finger DEAD PF00270.29 EWM23969.1 - 0.0014 18.5 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase GSHPx PF00255.19 EWM23970.1 - 1e-34 118.4 0.0 2.9e-34 116.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione peroxidase AhpC-TSA PF00578.21 EWM23970.1 - 7.7e-08 32.3 0.0 1.3e-07 31.6 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EWM23970.1 - 8.4e-05 22.3 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 Redoxin HhH-GPD PF00730.25 EWM23972.1 - 2.2e-18 66.7 0.0 3.8e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EWM23972.1 - 2.3e-09 36.6 0.0 5.8e-09 35.4 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 EWM23972.1 - 0.0042 17.7 0.0 0.011 16.3 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain EndIII_4Fe-2S PF10576.9 EWM23972.1 - 3.4 8.1 6.0 11 6.5 6.0 1.9 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Cpn60_TCP1 PF00118.24 EWM23973.1 - 5.4e-158 526.7 3.1 6.1e-158 526.5 3.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PHM7_cyt PF14703.6 EWM23974.1 - 4.6e-08 33.5 0.0 1e-07 32.4 0.0 1.6 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_7TM PF02714.15 EWM23974.1 - 2.6e-05 23.7 5.4 2.6e-05 23.7 5.4 2.6 3 1 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate KIAA1430 PF13879.6 EWM23974.1 - 0.55 11.0 2.5 31 5.4 0.3 2.3 2 0 0 2 2 2 0 KIAA1430 homologue FA_desaturase PF00487.24 EWM23975.1 - 2e-13 50.8 23.9 3.8e-13 49.9 23.9 1.4 1 0 0 1 1 1 1 Fatty acid desaturase COX6B PF02297.17 EWM23976.1 - 1.5e-10 41.1 4.7 2e-10 40.7 4.7 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb SpoU_methylase PF00588.19 EWM23976.1 - 0.1 12.7 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 SpoU rRNA Methylase family tRNA-synt_2b PF00587.25 EWM23977.1 - 7.6e-32 110.7 0.0 7.9e-29 100.9 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EWM23977.1 - 1.5e-20 73.1 0.1 3.1e-20 72.1 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 EWM23977.1 - 2.4e-09 37.1 0.0 4.8e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 EWM23977.1 - 1.6e-08 34.4 0.0 3.3e-07 30.3 0.0 2.7 2 1 0 2 2 2 1 TGS domain Hyaluronidase_1 PF07212.11 EWM23977.1 - 0.16 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Hyaluronidase protein (HylP) AA_permease_2 PF13520.6 EWM23978.1 - 5.2e-33 114.5 29.2 5.2e-33 114.5 29.2 1.5 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EWM23978.1 - 1.5e-22 79.9 30.6 1.8e-22 79.6 30.0 1.5 1 1 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 EWM23978.1 - 5.5e-10 39.2 3.7 5.5e-10 39.2 3.7 3.7 4 1 1 5 5 5 1 C-terminus of AA_permease PrgI PF12666.7 EWM23978.1 - 1.2 9.9 0.0 1.2 9.9 0.0 4.6 3 1 1 4 4 4 0 PrgI family protein DUF3593 PF12159.8 EWM23979.1 - 0.19 11.8 0.1 0.38 10.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3593) Lin-8 PF03353.15 EWM23980.1 - 0.091 12.3 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Nup188 PF10487.9 EWM23981.1 - 2e-05 22.8 0.0 0.0029 15.6 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 RuvX PF03652.15 EWM23982.1 - 4.7e-21 75.6 0.0 6.8e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Holliday junction resolvase RuvX PF03652.15 EWM23983.1 - 4.7e-21 75.6 0.0 6.8e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Holliday junction resolvase Cyclin_C PF02984.19 EWM23984.1 - 0.092 12.8 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 Cyclin, C-terminal domain ATG101 PF07855.12 EWM23984.1 - 0.15 12.0 0.1 0.23 11.4 0.1 1.2 1 0 0 1 1 1 0 Autophagy-related protein 101 ORC6 PF05460.13 EWM23984.1 - 0.28 10.4 11.5 3 7.0 11.5 2.0 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) AKAP7_RIRII_bdg PF10470.9 EWM23985.1 - 0.0074 16.3 0.5 0.014 15.4 0.5 1.4 1 0 0 1 1 1 1 PKA-RI-RII subunit binding domain of A-kinase anchor protein AAA_30 PF13604.6 EWM23986.1 - 9.4e-44 149.4 2.2 2.6e-43 148.0 2.2 1.8 1 0 0 1 1 1 1 AAA domain HHH_4 PF14490.6 EWM23986.1 - 4.6e-33 113.1 0.0 1.6e-27 95.3 0.0 2.5 2 0 0 2 2 2 2 Helix-hairpin-helix containing domain AAA_19 PF13245.6 EWM23986.1 - 4.3e-30 105.0 0.1 1.1e-29 103.7 0.1 1.7 1 0 0 1 1 1 1 AAA domain SH3_13 PF18335.1 EWM23986.1 - 1.5e-20 72.8 0.1 3.2e-20 71.7 0.1 1.6 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain UvrD_C_2 PF13538.6 EWM23986.1 - 4.4e-15 55.2 1.7 1e-14 54.1 1.1 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EWM23986.1 - 2.9e-11 43.6 0.0 8.6e-05 22.4 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase HHH_5 PF14520.6 EWM23986.1 - 4.7e-09 36.7 0.1 3.8e-07 30.6 0.0 3.3 3 0 0 3 3 3 1 Helix-hairpin-helix domain AAA_11 PF13086.6 EWM23986.1 - 5.5e-08 32.9 0.2 0.001 19.0 0.1 2.4 2 0 0 2 2 2 2 AAA domain PIF1 PF05970.14 EWM23986.1 - 8.2e-08 31.8 0.0 2.9e-07 30.0 0.0 1.8 1 1 0 1 1 1 1 PIF1-like helicase Helicase_RecD PF05127.14 EWM23986.1 - 1.2e-07 31.8 0.1 2.9e-07 30.5 0.1 1.7 1 0 0 1 1 1 1 Helicase AAA_28 PF13521.6 EWM23986.1 - 0.00019 21.7 0.1 0.00068 19.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EWM23986.1 - 0.0017 18.6 0.0 0.0061 16.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain HHH_2 PF12826.7 EWM23986.1 - 0.0033 17.5 0.0 0.01 15.9 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF2075 PF09848.9 EWM23986.1 - 0.0041 16.4 0.0 0.015 14.5 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 EWM23986.1 - 0.0077 16.6 0.1 0.029 14.8 0.1 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EWM23986.1 - 0.0077 16.6 0.0 0.024 15.0 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EWM23986.1 - 0.011 15.2 0.9 3.9 6.9 0.7 2.4 1 1 1 2 2 2 0 PhoH-like protein NTPase_1 PF03266.15 EWM23986.1 - 0.012 15.5 0.1 0.064 13.2 0.0 2.3 2 0 0 2 2 1 0 NTPase AAA_24 PF13479.6 EWM23986.1 - 0.013 15.3 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EWM23986.1 - 0.025 13.9 0.1 0.057 12.8 0.1 1.5 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.6 EWM23986.1 - 0.039 13.5 0.7 0.15 11.6 0.7 2.0 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EWM23986.1 - 0.045 12.8 0.0 0.08 12.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein MeaB PF03308.16 EWM23986.1 - 0.061 12.3 0.1 0.12 11.3 0.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TIP49 PF06068.13 EWM23986.1 - 0.064 12.4 0.7 0.68 9.1 0.1 2.1 2 0 0 2 2 2 0 TIP49 P-loop domain DnaB_C PF03796.15 EWM23986.1 - 0.069 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain ABC_tran PF00005.27 EWM23986.1 - 0.078 13.5 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter CbiA PF01656.23 EWM23986.1 - 0.089 12.9 0.2 0.36 10.9 0.1 2.0 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_5 PF07728.14 EWM23986.1 - 0.12 12.4 0.1 0.49 10.4 0.1 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TrwB_AAD_bind PF10412.9 EWM23986.1 - 0.13 11.2 0.2 0.22 10.4 0.2 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain HHH PF00633.23 EWM23986.1 - 0.14 12.1 0.2 30 4.8 0.1 3.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif IstB_IS21 PF01695.17 EWM23986.1 - 0.27 11.0 0.8 2 8.1 0.7 2.4 1 1 1 2 2 2 0 IstB-like ATP binding protein Mtc PF03820.17 EWM23988.1 - 1.1e-82 277.6 0.0 1.2e-82 277.4 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier UPF0020 PF01170.18 EWM23989.1 - 5e-09 36.1 0.1 5.4e-08 32.7 0.1 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 EWM23989.1 - 2.2e-05 24.3 0.0 0.25 11.0 0.0 2.4 2 0 0 2 2 2 2 DNA methylase N6_Mtase PF02384.16 EWM23989.1 - 0.01 15.1 0.0 0.022 14.0 0.0 1.5 1 1 0 1 1 1 0 N-6 DNA Methylase MethyltransfD12 PF02086.15 EWM23989.1 - 0.054 13.2 0.1 2.1 7.9 0.0 2.4 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase Dynamitin PF04912.14 EWM23990.1 - 1.2e-41 143.3 0.0 9.4e-41 140.4 0.0 1.9 1 1 0 1 1 1 1 Dynamitin DUF2408 PF10303.9 EWM23990.1 - 0.0011 19.6 2.0 0.027 15.1 2.0 2.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2408) GAIN_A PF18619.1 EWM23990.1 - 0.073 13.3 0.1 0.23 11.7 0.1 1.9 1 0 0 1 1 1 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A BLOC1_2 PF10046.9 EWM23990.1 - 0.61 10.4 2.4 21 5.5 0.3 3.3 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MRP-S26 PF14943.6 EWM23991.1 - 4.8e-06 26.6 19.8 2e-05 24.6 16.6 2.1 2 0 0 2 2 2 1 Mitochondrial ribosome subunit S26 PhaP_Bmeg PF09602.10 EWM23991.1 - 0.012 15.6 7.8 0.012 15.6 7.8 1.7 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Anthrax_toxA PF03497.16 EWM23991.1 - 0.29 11.2 3.7 0.5 10.5 3.7 1.3 1 0 0 1 1 1 0 Anthrax toxin LF subunit Enkurin PF13864.6 EWM23991.1 - 5.1 7.6 14.1 2.9 8.4 10.7 2.1 2 1 0 2 2 2 0 Calmodulin-binding Tho2 PF11262.8 EWM23991.1 - 5.6 6.1 9.7 10 5.2 9.7 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 SR-25 PF10500.9 EWM23992.1 - 0.42 10.2 4.8 0.81 9.3 4.8 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ncstrn_small PF18266.1 EWM23993.1 - 2.6e-19 69.9 0.0 5.1e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Nicastrin small lobe Nicastrin PF05450.15 EWM23993.1 - 1.6e-18 67.0 0.0 5.8e-09 35.7 0.0 2.2 2 0 0 2 2 2 2 Nicastrin Peptidase_M28 PF04389.17 EWM23993.1 - 7.9e-05 22.4 0.0 0.00032 20.4 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M28 Glyoxalase_4 PF13669.6 EWM23995.1 - 7.6e-17 61.6 0.0 1.2e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EWM23995.1 - 0.028 14.5 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase-like domain WW PF00397.26 EWM23996.1 - 7.9e-06 25.9 9.1 1.5e-05 24.9 9.1 1.5 1 0 0 1 1 1 1 WW domain WD40 PF00400.32 EWM23997.1 - 4.6e-10 39.9 0.1 0.00043 21.0 0.0 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM23997.1 - 0.1 12.9 0.0 0.77 10.1 0.0 2.5 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Metallophos PF00149.28 EWM23998.1 - 1.7e-10 41.7 0.0 3.6e-10 40.7 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Peptidase_C12 PF01088.21 EWM23999.1 - 2.3e-54 184.4 0.0 3e-54 184.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 RRM_1 PF00076.22 EWM24001.1 - 5.8e-21 74.1 0.0 8.4e-21 73.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CH PF00307.31 EWM24002.1 - 5.3e-23 81.3 0.0 8e-23 80.7 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EWM24002.1 - 0.00061 19.6 0.0 0.00094 19.0 0.0 1.3 1 0 0 1 1 1 1 CAMSAP CH domain CDC24 PF06395.11 EWM24002.1 - 0.0011 19.2 0.0 0.002 18.4 0.0 1.3 1 0 0 1 1 1 1 CDC24 Calponin GMC_oxred_N PF00732.19 EWM24003.1 - 2.3e-30 106.0 0.0 3.1e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EWM24003.1 - 4.9e-27 95.2 0.1 8.4e-27 94.5 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NIR_SIR PF01077.22 EWM24004.1 - 1.5e-49 167.5 0.0 3.5e-41 140.4 0.1 2.2 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 EWM24004.1 - 4.5e-28 96.9 0.0 1.1e-14 54.1 0.0 2.8 3 0 0 3 3 3 2 Nitrite/Sulfite reductase ferredoxin-like half domain Orbi_VP4 PF05059.12 EWM24004.1 - 0.13 10.2 0.0 0.19 9.7 0.0 1.1 1 0 0 1 1 1 0 Orbivirus VP4 core protein DUF647 PF04884.14 EWM24005.1 - 8.7e-61 205.6 1.3 1.3e-60 205.0 1.3 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DUF1084 PF06454.11 EWM24006.1 - 1.1e-13 51.2 9.4 2e-13 50.3 9.4 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) IBN_N PF03810.19 EWM24007.1 - 1.3e-09 37.8 1.6 3.7e-09 36.4 1.6 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain Methyltransf_16 PF10294.9 EWM24008.1 - 1.7e-08 34.4 0.0 3.5e-08 33.4 0.0 1.5 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EWM24008.1 - 0.0068 16.3 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Rieske PF00355.26 EWM24009.1 - 5.3e-16 58.3 0.0 8.5e-16 57.7 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 EWM24009.1 - 9.2e-13 48.0 0.0 1.5e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain DUF3341 PF11821.8 EWM24011.1 - 0.035 13.7 1.7 1.2 8.7 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3341) MRG PF05712.13 EWM24012.1 - 1.5e-43 148.4 0.0 2.1e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 EWM24012.1 - 1.9e-09 37.3 0.1 4e-09 36.2 0.1 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 EWM24012.1 - 0.017 15.0 0.5 0.033 14.1 0.5 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain ENOD93 PF03386.14 EWM24013.1 - 0.00021 21.1 0.0 0.00038 20.3 0.0 1.4 1 0 0 1 1 1 1 Early nodulin 93 ENOD93 protein HIG_1_N PF04588.13 EWM24013.1 - 0.039 14.2 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 Hypoxia induced protein conserved region HEM4 PF02602.15 EWM24015.1 - 3.2e-31 108.5 0.6 2e-30 105.8 0.6 1.9 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Pantoate_ligase PF02569.15 EWM24015.1 - 0.12 11.6 0.0 3.9 6.6 0.0 2.4 1 1 2 3 3 3 0 Pantoate-beta-alanine ligase AAA_2 PF07724.14 EWM24016.1 - 8.7e-54 182.2 2.8 1.2e-48 165.5 0.0 3.6 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EWM24016.1 - 6.9e-33 112.7 11.3 9.8e-33 112.2 5.1 3.3 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 EWM24016.1 - 1.6e-26 92.1 1.0 7e-26 90.1 0.1 2.8 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 EWM24016.1 - 8.3e-25 87.7 4.0 4.7e-14 53.0 0.0 3.6 4 0 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) Clp_N PF02861.20 EWM24016.1 - 3.2e-18 65.6 0.6 2.2e-13 50.1 0.1 3.1 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_5 PF07728.14 EWM24016.1 - 3.5e-15 56.2 0.9 2.6e-09 37.2 0.0 3.9 3 1 1 4 4 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EWM24016.1 - 2.8e-11 44.1 0.5 0.00034 21.0 0.0 4.4 4 1 0 4 4 2 2 AAA ATPase domain Sigma54_activat PF00158.26 EWM24016.1 - 1.7e-08 34.3 0.0 7.3e-05 22.5 0.0 2.7 2 1 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 EWM24016.1 - 5.6e-07 29.4 0.0 0.021 14.6 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 EWM24016.1 - 2.1e-06 27.4 0.0 0.0024 17.4 0.0 3.0 3 1 0 3 3 2 1 P-loop containing dynein motor region TniB PF05621.11 EWM24016.1 - 4.5e-06 26.2 0.3 0.0063 16.0 0.1 4.0 3 2 0 3 3 3 1 Bacterial TniB protein AAA_14 PF13173.6 EWM24016.1 - 5.8e-06 26.4 0.0 0.19 11.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EWM24016.1 - 6.7e-06 26.4 7.8 0.087 13.1 0.3 5.1 4 2 0 4 4 4 2 AAA domain Mg_chelatase PF01078.21 EWM24016.1 - 1.8e-05 24.2 0.2 0.058 12.8 0.1 3.3 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI Roc PF08477.13 EWM24016.1 - 5.9e-05 23.3 0.3 0.13 12.5 0.0 3.4 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 EWM24016.1 - 7e-05 22.8 0.0 0.25 11.2 0.0 3.3 3 0 0 3 3 2 2 NACHT domain AAA_18 PF13238.6 EWM24016.1 - 0.00011 22.7 0.1 0.88 10.1 0.0 3.9 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.12 EWM24016.1 - 0.00012 21.9 0.8 2.9 7.6 0.4 3.9 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 EWM24016.1 - 0.0003 20.8 0.2 2.4 8.0 0.0 4.2 3 2 0 4 4 3 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 EWM24016.1 - 0.00031 21.1 0.4 1.1 9.7 0.0 3.3 3 0 0 3 3 2 2 RNA helicase AAA_25 PF13481.6 EWM24016.1 - 0.00076 19.1 0.3 0.12 12.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 EWM24016.1 - 0.0022 18.5 0.3 0.31 11.5 0.0 3.4 3 0 0 3 3 3 1 ABC transporter ResIII PF04851.15 EWM24016.1 - 0.0031 17.5 0.0 0.51 10.3 0.0 3.4 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_24 PF13479.6 EWM24016.1 - 0.0031 17.2 0.1 1.5 8.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 EWM24016.1 - 0.0034 17.3 0.6 1.4 8.8 0.0 3.4 4 0 0 4 4 2 1 RsgA GTPase Zeta_toxin PF06414.12 EWM24016.1 - 0.0044 16.3 0.0 1.7 7.8 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin TsaE PF02367.17 EWM24016.1 - 0.0052 16.8 0.0 5.2 7.1 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Torsin PF06309.11 EWM24016.1 - 0.0054 16.8 0.0 0.036 14.2 0.0 2.2 2 0 0 2 2 2 1 Torsin AAA_33 PF13671.6 EWM24016.1 - 0.0059 16.8 0.4 4 7.6 0.0 3.4 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.6 EWM24016.1 - 0.0083 16.4 2.2 13 6.0 0.0 4.4 4 1 1 5 5 5 0 AAA domain ABC_tran_CTD PF16326.5 EWM24016.1 - 0.014 15.7 4.8 0.014 15.7 4.8 3.6 3 0 0 3 3 3 0 ABC transporter C-terminal domain HBM PF16591.5 EWM24016.1 - 0.027 13.9 8.8 0.025 14.0 5.5 2.5 2 1 1 3 3 3 0 Helical bimodular sensor domain SRP54 PF00448.22 EWM24016.1 - 0.052 13.2 2.8 1.1 8.8 0.0 3.3 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain PhoH PF02562.16 EWM24016.1 - 0.059 12.8 0.0 3.3 7.1 0.0 2.8 3 0 0 3 3 2 0 PhoH-like protein AAA_3 PF07726.11 EWM24016.1 - 0.091 12.6 0.1 20 5.1 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FlxA PF14282.6 EWM24016.1 - 0.24 11.4 6.0 0.73 9.9 6.0 1.9 1 0 0 1 1 1 0 FlxA-like protein T3SS_needle_E PF08988.10 EWM24016.1 - 0.26 11.5 5.1 28 5.0 0.0 4.3 3 0 0 3 3 3 0 Type III secretion system, cytoplasmic E component of needle GPS2_interact PF15784.5 EWM24016.1 - 6.3 7.3 10.0 31 5.1 9.2 2.6 1 1 1 2 2 2 0 G-protein pathway suppressor 2-interacting domain LUC7 PF03194.15 EWM24016.1 - 7.9 6.1 8.3 2.4 7.8 5.1 1.7 2 0 0 2 2 1 0 LUC7 N_terminus Telomere_reg-2 PF10193.9 EWM24017.1 - 6.6e-25 87.7 0.0 1.2e-22 80.4 0.0 2.5 2 0 0 2 2 2 2 Telomere length regulation protein Abhydrolase_6 PF12697.7 EWM24018.1 - 5.5e-13 50.0 6.8 5.5e-13 50.0 6.8 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EWM24018.1 - 1.1e-11 44.5 0.0 5.7e-09 35.6 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EWM24018.1 - 5.5e-09 36.1 0.0 4.1e-08 33.2 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EWM24018.1 - 3.7e-05 23.7 0.4 8.3e-05 22.5 0.4 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EWM24018.1 - 0.0002 21.2 0.0 0.088 12.6 0.0 2.5 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Thioesterase PF00975.20 EWM24018.1 - 0.005 17.0 0.1 0.011 15.9 0.1 1.6 1 0 0 1 1 1 1 Thioesterase domain DUF818 PF05677.12 EWM24018.1 - 0.015 14.3 0.0 0.023 13.7 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) DUF2890 PF11081.8 EWM24018.1 - 0.026 14.7 0.1 0.16 12.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Abhydro_lipase PF04083.16 EWM24018.1 - 0.046 13.3 0.0 0.14 11.7 0.0 1.8 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region DLH PF01738.18 EWM24018.1 - 0.048 13.2 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family RNase_HII PF01351.18 EWM24019.1 - 5.9e-46 156.8 0.0 8e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII Tcp10_C PF07202.13 EWM24020.1 - 2.6e-20 73.1 0.0 5.8e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 T-complex protein 10 C-terminus DNA_pol_phi PF04931.13 EWM24020.1 - 8.7 4.3 15.1 0.59 8.2 10.0 1.5 2 0 0 2 2 2 0 DNA polymerase phi SLIDE PF09111.10 EWM24021.1 - 5.5e-38 129.5 0.7 5.5e-38 129.5 0.7 2.7 3 0 0 3 3 3 1 SLIDE HMG_box PF00505.19 EWM24021.1 - 4.7e-07 30.1 3.8 5.8e-07 29.8 1.5 2.5 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EWM24021.1 - 2.5e-05 24.8 1.3 0.00013 22.5 1.3 2.3 1 0 0 1 1 1 1 HMG-box domain DUF2244 PF10003.9 EWM24021.1 - 8.4 6.1 5.6 3.7 7.2 0.4 2.3 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Apolipoprotein PF01442.18 EWM24022.1 - 0.0004 20.3 31.6 0.0004 20.3 31.6 1.8 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain YtxH PF12732.7 EWM24022.1 - 0.0024 18.3 43.4 63 4.2 10.8 4.9 1 1 1 2 2 2 0 YtxH-like protein DUF883 PF05957.13 EWM24022.1 - 0.027 15.1 36.2 0.069 13.8 3.1 4.4 1 1 4 5 5 5 0 Bacterial protein of unknown function (DUF883) Exonuc_VII_L PF02601.15 EWM24022.1 - 1.3 8.5 12.9 1.9 8.0 12.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phtf-FEM1B_bdg PF12129.8 EWM24024.1 - 4.3e-09 36.4 0.0 6.3e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Male germ-cell putative homeodomain transcription factor Nop14 PF04147.12 EWM24024.1 - 8.5e-05 21.0 18.2 0.0001 20.7 18.2 1.0 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 EWM24024.1 - 0.0035 16.8 20.1 0.0048 16.4 20.1 1.1 1 0 0 1 1 1 1 SDA1 TFIIA PF03153.13 EWM24024.1 - 0.033 14.2 13.2 0.045 13.7 13.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 EWM24024.1 - 0.035 13.5 16.1 0.052 12.9 16.1 1.2 1 0 0 1 1 1 0 BUD22 Dynactin_p62 PF05502.13 EWM24024.1 - 0.15 10.9 1.5 0.22 10.3 1.5 1.2 1 0 0 1 1 1 0 Dynactin p62 family MCPVI PF02993.14 EWM24024.1 - 1.2 8.9 4.1 2.4 8.0 4.1 1.5 1 0 0 1 1 1 0 Minor capsid protein VI SAPS PF04499.15 EWM24024.1 - 1.5 7.6 7.0 1.8 7.2 7.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 EWM24024.1 - 1.9 7.2 7.4 2.7 6.7 7.4 1.2 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 EWM24024.1 - 5.2 6.2 6.2 9.1 5.4 6.2 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Cluap1 PF10234.9 EWM24025.1 - 3.8e-20 72.4 7.7 6.2e-20 71.7 7.7 1.2 1 0 0 1 1 1 1 Clusterin-associated protein-1 Fez1 PF06818.15 EWM24025.1 - 0.0021 18.6 7.2 0.0033 17.9 7.2 1.3 1 0 0 1 1 1 1 Fez1 Cep57_CLD_2 PF14197.6 EWM24025.1 - 0.006 16.7 6.6 0.006 16.7 6.6 2.9 2 1 1 3 3 3 1 Centrosome localisation domain of PPC89 Rbsn PF11464.8 EWM24025.1 - 0.026 14.2 1.3 1.2 8.9 0.5 2.6 2 0 0 2 2 2 0 Rabenosyn Rab binding domain GIT_CC PF16559.5 EWM24025.1 - 0.4 10.6 6.3 0.78 9.7 0.7 2.9 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor KASH_CCD PF14662.6 EWM24025.1 - 0.51 10.1 15.2 0.78 9.5 15.2 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Fib_alpha PF08702.10 EWM24025.1 - 0.87 9.8 4.1 1.4 9.0 4.1 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family ADIP PF11559.8 EWM24025.1 - 1 9.4 12.7 3.9 7.5 2.6 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 EWM24025.1 - 1.2 9.0 12.0 0.75 9.6 2.8 2.5 1 1 1 2 2 2 0 Septum formation initiator FUSC PF04632.12 EWM24025.1 - 1.5 7.3 7.6 1.8 7.0 7.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4407 PF14362.6 EWM24025.1 - 1.7 7.9 4.4 2.5 7.4 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 EWM24025.1 - 1.9 7.5 7.4 3 6.8 7.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Occludin_ELL PF07303.13 EWM24025.1 - 3.7 8.3 8.0 0.7 10.7 2.3 2.2 1 1 1 2 2 2 0 Occludin homology domain DASH_Spc34 PF08657.10 EWM24025.1 - 5.5 6.7 8.5 9.3 6.0 4.3 2.3 1 1 1 2 2 2 0 DASH complex subunit Spc34 DUF1921 PF09081.10 EWM24027.1 - 0.11 12.7 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1921) UcrQ PF02939.16 EWM24028.1 - 7.7e-11 41.8 0.1 9.8e-11 41.4 0.1 1.1 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 EWM24028.1 - 3.5e-05 24.1 0.0 4.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b-c1 complex subunit 8 Patatin PF01734.22 EWM24029.1 - 3.5e-08 33.9 12.8 2.3e-07 31.2 10.8 2.8 2 1 0 2 2 2 1 Patatin-like phospholipase TIP49 PF06068.13 EWM24030.1 - 1.4e-155 517.8 0.4 1.4e-155 517.8 0.4 1.3 2 0 0 2 2 2 1 TIP49 P-loop domain TIP49_C PF17856.1 EWM24030.1 - 5.2e-27 93.8 0.7 1.2e-26 92.6 0.7 1.7 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 EWM24030.1 - 3.8e-10 40.3 1.3 3.4e-06 27.5 0.1 3.4 2 1 1 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EWM24030.1 - 8.6e-07 29.0 0.2 0.00029 20.9 0.1 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EWM24030.1 - 2.2e-06 28.0 0.4 0.076 13.3 0.0 2.6 1 1 0 2 2 2 2 AAA domain DnaB_C PF03796.15 EWM24030.1 - 7.2e-06 25.5 0.6 1.3e-05 24.7 0.2 1.6 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain RuvB_N PF05496.12 EWM24030.1 - 9.2e-06 25.5 0.2 0.0058 16.4 0.1 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 EWM24030.1 - 2.8e-05 23.8 0.2 7.6e-05 22.4 0.2 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EWM24030.1 - 0.00026 21.4 2.5 0.014 15.8 2.5 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EWM24030.1 - 0.00027 21.4 0.5 0.0014 19.1 0.5 2.2 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 EWM24030.1 - 0.00037 19.9 1.0 0.01 15.3 0.4 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 EWM24030.1 - 0.00088 19.2 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Zeta_toxin PF06414.12 EWM24030.1 - 0.0011 18.3 0.5 0.004 16.5 0.6 1.8 2 0 0 2 2 2 1 Zeta toxin Sigma54_activat PF00158.26 EWM24030.1 - 0.0019 17.9 0.1 1 9.0 0.1 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.6 EWM24030.1 - 0.0034 17.6 0.2 0.0096 16.2 0.2 1.8 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EWM24030.1 - 0.0056 16.0 0.2 0.0097 15.3 0.2 1.5 1 0 0 1 1 1 1 KaiC AAA_33 PF13671.6 EWM24030.1 - 0.022 14.9 0.0 0.046 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EWM24030.1 - 0.023 15.3 0.1 0.16 12.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EWM24030.1 - 0.048 13.5 0.0 0.095 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EWM24030.1 - 0.058 12.9 0.4 0.19 11.2 0.1 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 EWM24030.1 - 0.073 13.1 1.6 0.13 12.2 0.4 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EWM24030.1 - 0.081 12.6 3.0 0.56 9.9 1.1 2.3 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 EWM24030.1 - 0.084 12.9 0.4 3.1 7.8 0.4 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CbiA PF01656.23 EWM24030.1 - 0.091 12.8 0.0 1.3 9.1 0.3 2.2 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain KTI12 PF08433.10 EWM24030.1 - 0.1 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF2075 PF09848.9 EWM24030.1 - 0.11 11.7 0.1 0.2 10.9 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CK_II_beta PF01214.18 EWM24032.1 - 1.1e-73 246.9 0.0 1.1e-73 246.9 0.0 1.5 2 0 0 2 2 1 1 Casein kinase II regulatory subunit SDA1 PF05285.12 EWM24032.1 - 0.00011 21.8 9.4 0.00011 21.8 9.4 1.7 2 0 0 2 2 2 1 SDA1 SpoIIIAH PF12685.7 EWM24032.1 - 0.017 15.0 2.1 0.017 15.0 2.1 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein FYDLN_acid PF09538.10 EWM24032.1 - 0.018 15.7 11.7 0.053 14.2 9.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) RNA_pol_3_Rpc31 PF11705.8 EWM24032.1 - 0.028 14.7 19.9 0.08 13.2 19.9 1.8 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 PBP1_TM PF14812.6 EWM24032.1 - 0.054 13.9 6.9 0.22 11.9 6.9 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.12 EWM24032.1 - 0.087 11.0 18.4 0.14 10.3 18.4 1.3 1 0 0 1 1 1 0 Nop14-like family DUF3292 PF11696.8 EWM24032.1 - 0.13 10.6 7.3 0.18 10.1 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Mpp10 PF04006.12 EWM24032.1 - 0.28 9.6 18.9 0.53 8.7 18.9 1.3 1 0 0 1 1 1 0 Mpp10 protein PAP_RNA-bind PF04926.15 EWM24032.1 - 0.46 10.1 4.2 0.87 9.2 4.2 1.4 1 0 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain RPN2_C PF18004.1 EWM24032.1 - 1.2 9.0 13.7 3 7.8 13.7 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF2052 PF09747.9 EWM24032.1 - 1.5 8.9 20.5 0.034 14.3 13.0 2.0 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Porph_ging PF09697.10 EWM24032.1 - 1.6 9.3 6.7 6.5 7.4 6.7 2.1 1 0 0 1 1 1 0 Protein of unknown function (Porph_ging) RPA43_OB PF17875.1 EWM24032.1 - 1.8 9.2 7.0 39 4.9 9.0 2.1 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I AAA_23 PF13476.6 EWM24032.1 - 1.9 8.9 11.1 3.9 7.9 11.1 1.5 1 0 0 1 1 1 0 AAA domain Merozoite_SPAM PF07133.11 EWM24032.1 - 2.6 8.0 34.0 5.4 7.0 34.0 1.5 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) FancD2 PF14631.6 EWM24032.1 - 3.6 4.9 5.7 4.8 4.4 5.7 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Connexin PF00029.19 EWM24032.1 - 5.4 6.7 6.3 12 5.6 6.3 1.5 1 0 0 1 1 1 0 Connexin TRAP_alpha PF03896.16 EWM24032.1 - 5.5 6.1 12.9 9.5 5.3 12.9 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit V_ATPase_I PF01496.19 EWM24032.1 - 5.5 4.8 6.4 9 4.1 6.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DNA_pol_phi PF04931.13 EWM24032.1 - 5.8 4.9 28.1 8.2 4.4 28.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi DDRGK PF09756.9 EWM24032.1 - 6.8 6.2 21.7 0.34 10.5 15.8 1.8 2 0 0 2 2 1 0 DDRGK domain Tim54 PF11711.8 EWM24032.1 - 8.3 5.1 12.0 16 4.2 12.0 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RRN3 PF05327.11 EWM24032.1 - 9.7 4.6 10.4 14 4.1 10.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BT1 PF03092.16 EWM24033.1 - 3.1e-48 164.3 16.3 1.2e-27 96.4 4.0 3.0 1 1 1 3 3 3 3 BT1 family MFS_1 PF07690.16 EWM24033.1 - 2.7e-10 39.7 35.4 2.7e-10 39.7 35.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily NHL PF01436.21 EWM24034.1 - 2.1e-22 77.9 1.8 0.0013 18.7 0.0 6.9 7 0 0 7 7 7 5 NHL repeat Thioredoxin_8 PF13905.6 EWM24034.1 - 1e-11 45.0 0.0 2e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EWM24034.1 - 5.3e-08 32.8 0.0 1.1e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EWM24034.1 - 1.2e-06 28.4 0.0 4.2e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 Redoxin SGL PF08450.12 EWM24034.1 - 9.7e-05 22.1 0.0 0.15 11.6 0.0 3.1 2 1 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region Thioredoxin PF00085.20 EWM24034.1 - 0.0022 17.9 0.0 0.0073 16.3 0.1 1.7 1 1 1 2 2 2 1 Thioredoxin PQQ_3 PF13570.6 EWM24034.1 - 0.013 15.9 0.5 14 6.3 0.0 4.4 5 0 0 5 5 5 0 PQQ-like domain GYF PF02213.16 EWM24035.1 - 4.1e-10 39.2 0.0 1e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 GYF domain PQQ PF01011.21 EWM24035.1 - 0.054 13.4 0.8 1.1 9.4 0.1 2.4 2 0 0 2 2 2 0 PQQ enzyme repeat UBN_AB PF14075.6 EWM24035.1 - 0.12 12.1 2.4 0.23 11.1 2.4 1.4 1 0 0 1 1 1 0 Ubinuclein conserved middle domain DUF4407 PF14362.6 EWM24037.1 - 0.95 8.8 2.4 1.8 7.8 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SNF2_N PF00176.23 EWM24038.1 - 1.8e-76 257.1 0.7 5.9e-76 255.5 0.7 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EWM24038.1 - 4.7e-22 78.4 0.0 2.8e-21 76.0 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EWM24038.1 - 2.3e-11 44.0 0.1 2.2e-09 37.5 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HMG_box_2 PF09011.10 EWM24038.1 - 1.6e-10 41.4 0.2 5.7e-10 39.6 0.2 2.0 1 0 0 1 1 1 1 HMG-box domain HDA2-3 PF11496.8 EWM24038.1 - 5.6e-08 32.3 0.1 1.3e-07 31.1 0.1 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 EWM24038.1 - 9.3e-08 32.0 0.0 5e-07 29.7 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase HMG_box PF00505.19 EWM24038.1 - 4.9e-07 30.1 0.0 1.5e-06 28.5 0.0 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box SWI2_SNF2 PF18766.1 EWM24038.1 - 0.0016 18.2 0.0 0.0045 16.7 0.0 1.8 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF4407 PF14362.6 EWM24038.1 - 0.17 11.2 13.8 0.32 10.3 13.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MobB PF03205.14 EWM24038.1 - 0.23 11.3 1.6 0.6 10.0 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF4449 PF14613.6 EWM24038.1 - 3.2 7.8 12.4 1.9 8.6 2.9 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4449) PolyA_pol PF01743.20 EWM24040.1 - 2.4e-27 95.8 0.0 3.5e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Poly A polymerase head domain HEAT PF02985.22 EWM24041.1 - 0.00014 21.8 4.0 1.3 9.4 0.2 4.0 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 EWM24041.1 - 0.00078 19.8 0.2 0.31 11.4 0.1 2.7 3 0 0 3 3 3 2 HEAT repeats DUF3014 PF11219.8 EWM24041.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3014) Pkinase PF00069.25 EWM24042.1 - 8.4e-39 133.5 0.0 1.1e-38 133.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM24042.1 - 3.1e-19 69.3 0.0 4.3e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 EWM24042.1 - 0.019 14.6 0.0 3.5 7.2 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EWM24042.1 - 0.094 12.6 0.4 0.52 10.2 0.5 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family ZZ PF00569.17 EWM24043.1 - 1.6e-07 31.0 12.5 3.9e-07 29.8 12.5 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type F-box-like PF12937.7 EWM24043.1 - 2.7e-07 30.3 0.3 6.5e-07 29.2 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EWM24043.1 - 2.3e-06 27.3 0.5 4.3e-06 26.5 0.5 1.4 1 0 0 1 1 1 1 F-box domain USP7_ICP0_bdg PF12436.8 EWM24043.1 - 0.053 12.8 0.0 0.19 11.0 0.0 1.8 2 0 0 2 2 2 0 ICP0-binding domain of Ubiquitin-specific protease 7 DIOX_N PF14226.6 EWM24044.1 - 4.5e-07 30.6 0.0 9.7e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EWM24044.1 - 0.00015 22.2 0.0 0.00052 20.5 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CPP1-like PF11833.8 EWM24045.1 - 0.02 14.6 0.2 0.02 14.6 0.2 1.6 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Glyco_hydro_16 PF00722.21 EWM24047.1 - 3.1e-07 30.0 0.1 6.2e-07 29.0 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Tubulin PF00091.25 EWM24048.1 - 1.4e-56 191.8 0.0 2.3e-56 191.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EWM24048.1 - 4.3e-14 52.7 0.0 1.9e-13 50.7 0.0 1.9 1 1 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EWM24048.1 - 0.0065 16.8 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 EWM24048.1 - 0.011 15.0 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Tubulin like PI3_PI4_kinase PF00454.27 EWM24051.1 - 3.9e-70 236.5 0.0 7.9e-70 235.5 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 EWM24051.1 - 5.4e-67 226.5 0.0 1.7e-65 221.5 0.0 3.1 1 1 0 1 1 1 1 FAT domain DUF3385 PF11865.8 EWM24051.1 - 2.8e-43 147.6 0.0 2e-40 138.4 0.0 3.3 2 1 0 2 2 2 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 EWM24051.1 - 4.7e-36 123.2 0.0 2.4e-35 120.9 0.0 2.3 1 1 0 1 1 1 1 FKBP12-rapamycin binding domain FATC PF02260.20 EWM24051.1 - 2.9e-14 52.6 0.1 6.7e-14 51.4 0.1 1.7 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 EWM24051.1 - 6.6e-05 22.8 9.4 0.11 12.9 0.0 6.5 6 0 0 6 6 5 1 HEAT repeat HEAT_2 PF13646.6 EWM24051.1 - 0.00029 21.1 14.6 0.26 11.7 0.4 6.7 6 1 1 7 7 7 1 HEAT repeats HEAT_EZ PF13513.6 EWM24051.1 - 0.0036 17.8 0.6 0.0036 17.8 0.6 9.1 9 1 1 10 10 10 2 HEAT-like repeat DUF3150 PF11348.8 EWM24051.1 - 0.017 14.4 0.0 0.036 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) TPR_7 PF13176.6 EWM24051.1 - 0.43 10.7 3.8 1.6 8.9 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EWM24051.1 - 1.6 9.3 11.8 9.6 6.8 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 EWM24051.1 - 4.4 8.4 11.1 12 7.1 0.1 6.5 5 0 0 5 5 3 0 Tetratricopeptide repeat zf-AN1 PF01428.16 EWM24053.1 - 2.3e-15 56.5 35.3 4.2e-09 36.4 13.0 3.9 3 1 1 4 4 4 2 AN1-like Zinc finger zf-Di19 PF05605.12 EWM24053.1 - 0.00028 21.1 0.6 0.00028 21.1 0.6 3.5 3 1 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 EWM24053.1 - 0.065 14.1 0.9 0.065 14.1 0.9 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger Sporozoite_P67 PF05642.11 EWM24053.1 - 4.9 5.1 12.2 6.3 4.7 12.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Acetyltransf_7 PF13508.7 EWM24055.1 - 0.021 15.3 0.0 0.043 14.3 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2973 PF11189.8 EWM24056.1 - 0.031 14.3 0.0 5.3 7.2 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) DEAD PF00270.29 EWM24057.1 - 1.2e-48 165.2 0.0 2.8e-48 164.0 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EWM24057.1 - 3.7e-25 88.4 0.0 7.8e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EWM24057.1 - 0.012 15.6 0.0 0.028 14.4 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Salt_tol_Pase PF09506.10 EWM24057.1 - 0.15 10.8 0.0 0.26 10.0 0.0 1.3 1 0 0 1 1 1 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) NUDIX PF00293.28 EWM24058.1 - 8.9e-19 67.8 0.0 1.1e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Macoilin PF09726.9 EWM24060.1 - 2 6.9 6.7 2.1 6.8 6.7 1.0 1 0 0 1 1 1 0 Macoilin family SelP_N PF04592.14 EWM24060.1 - 2 7.7 11.3 2.2 7.6 11.3 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.22 EWM24060.1 - 2.8 7.1 6.6 2.9 7.0 6.6 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter TIL PF01826.17 EWM24061.1 - 9.2e-07 29.0 16.0 1.4e-06 28.4 16.0 1.3 1 0 0 1 1 1 1 Trypsin Inhibitor like cysteine rich domain TIL PF01826.17 EWM24062.1 - 4e-07 30.2 16.0 5.9e-07 29.6 16.0 1.3 1 0 0 1 1 1 1 Trypsin Inhibitor like cysteine rich domain 2OG-FeII_Oxy_3 PF13640.6 EWM24063.1 - 3e-17 63.3 0.0 1.5e-16 61.0 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Blt1 PF12754.7 EWM24063.1 - 0.18 12.1 0.0 0.33 11.2 0.0 1.3 1 0 0 1 1 1 0 Blt1 N-terminal domain STI1 PF17830.1 EWM24065.1 - 0.0098 15.8 1.2 0.026 14.5 0.9 1.9 2 0 0 2 2 2 1 STI1 domain PutA_N PF18083.1 EWM24065.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Proline utilization A N-terminal domain Sec10 PF07393.11 EWM24065.1 - 0.17 10.3 0.1 0.24 9.8 0.1 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 Methyltrans_SAM PF10672.9 EWM24066.1 - 1.9e-19 69.9 0.0 2.6e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase PUA_3 PF17785.1 EWM24066.1 - 5.6e-15 54.9 0.1 1.1e-14 53.9 0.1 1.5 1 0 0 1 1 1 1 PUA-like domain Methyltransf_31 PF13847.6 EWM24066.1 - 1e-11 44.8 0.0 2.4e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EWM24066.1 - 2.4e-09 37.1 0.0 4.1e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 EWM24066.1 - 1.5e-07 32.1 0.0 5.9e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EWM24066.1 - 1.1e-06 28.3 0.0 1.9e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EWM24066.1 - 1.3e-06 28.1 0.0 1.9e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 EWM24066.1 - 0.00022 20.9 0.0 0.00035 20.2 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 EWM24066.1 - 0.00084 19.1 0.0 0.0017 18.1 0.0 1.5 2 0 0 2 2 2 1 Met-10+ like-protein UPF0020 PF01170.18 EWM24066.1 - 0.0032 17.2 0.0 0.014 15.0 0.0 1.9 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 PUA PF01472.20 EWM24066.1 - 0.0071 16.3 0.1 0.02 14.9 0.1 1.7 2 0 0 2 2 2 1 PUA domain UPF0113 PF03657.13 EWM24066.1 - 0.018 15.3 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 UPF0113 PUA domain Methyltransf_23 PF13489.6 EWM24066.1 - 0.031 14.1 0.0 0.094 12.6 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 EWM24066.1 - 0.13 12.3 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Epimerase PF01370.21 EWM24067.1 - 4.1e-44 150.9 0.0 5e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EWM24067.1 - 8e-28 97.8 0.0 1.5e-24 87.0 0.0 2.2 1 1 1 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EWM24067.1 - 7.4e-09 35.0 0.0 1.3e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EWM24067.1 - 3.4e-07 29.6 0.0 4.3e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EWM24067.1 - 8.3e-07 29.1 0.0 1.3e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EWM24067.1 - 1.2e-06 27.9 0.0 4.9e-05 22.6 0.0 2.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EWM24067.1 - 0.0043 16.5 0.0 0.0087 15.5 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.12 EWM24067.1 - 0.0077 15.4 0.0 0.21 10.7 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein NAD_binding_7 PF13241.6 EWM24067.1 - 0.16 12.4 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 EWM24067.1 - 0.19 12.0 0.0 0.56 10.5 0.0 1.8 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Proteasome PF00227.26 EWM24068.1 - 6e-49 166.1 0.7 8.5e-49 165.6 0.7 1.2 1 0 0 1 1 1 1 Proteasome subunit SelA PF03841.13 EWM24068.1 - 0.098 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase DENN PF02141.21 EWM24069.1 - 2.4e-30 105.9 2.2 1e-28 100.6 2.2 2.5 1 1 0 1 1 1 1 DENN (AEX-3) domain PDZ_6 PF17820.1 EWM24069.1 - 1.1e-09 38.0 0.1 2.4e-09 36.9 0.1 1.6 1 0 0 1 1 1 1 PDZ domain RGS PF00615.19 EWM24069.1 - 3e-06 27.5 0.0 0.009 16.3 0.0 2.5 2 0 0 2 2 2 2 Regulator of G protein signaling domain PDZ PF00595.24 EWM24069.1 - 0.0062 16.9 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain uDENN PF03456.18 EWM24069.1 - 0.043 14.6 0.9 0.36 11.6 0.0 3.1 3 0 0 3 3 3 0 uDENN domain CBF PF03914.17 EWM24070.1 - 1.5e-23 83.7 0.8 3.1e-23 82.7 0.2 1.9 2 0 0 2 2 2 1 CBF/Mak21 family DUF508 PF04370.12 EWM24070.1 - 0.15 11.8 0.8 0.33 10.7 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Aminotran_1_2 PF00155.21 EWM24071.1 - 1.5e-34 119.7 0.0 2.1e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EWM24071.1 - 2.1e-06 26.9 0.0 3e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EWM24071.1 - 0.0034 16.7 0.0 0.0044 16.3 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EWM24071.1 - 0.018 13.6 0.0 0.025 13.1 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme SKN1 PF03935.15 EWM24072.1 - 3.2e-22 78.6 0.8 5.1e-10 38.4 0.1 3.1 2 1 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.21 EWM24072.1 - 2.3e-05 24.0 0.1 0.00014 21.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 TMEM189_B_dmain PF10520.9 EWM24073.1 - 4.5e-18 66.0 0.1 6.3e-18 65.5 0.1 1.2 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain TMEM189_B_dmain PF10520.9 EWM24074.1 - 4.5e-18 66.0 0.1 6.3e-18 65.5 0.1 1.2 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain ELFV_dehydrog PF00208.21 EWM24075.1 - 8.6e-41 140.3 0.0 1.1e-40 139.9 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 EWM24075.1 - 9.7e-41 138.7 0.0 1.7e-40 137.9 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 EWM24075.1 - 0.031 14.7 0.0 0.06 13.8 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Oxidored_nitro PF00148.19 EWM24075.1 - 0.042 12.6 0.0 0.065 11.9 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Shikimate_DH PF01488.20 EWM24075.1 - 0.2 11.7 0.0 0.41 10.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RdRP PF05183.12 EWM24076.1 - 8.5e-10 37.9 0.0 1.1e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase SKN1 PF03935.15 EWM24077.1 - 5.9e-23 81.0 0.1 1.3e-22 79.9 0.1 1.4 1 1 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Rubis-subs-bind PF09273.11 EWM24078.1 - 9.4e-21 74.9 1.0 9.4e-21 74.9 1.0 2.0 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding SET PF00856.28 EWM24078.1 - 2.8e-12 47.3 0.0 8.7e-12 45.7 0.0 1.9 2 0 0 2 2 2 1 SET domain AP_endonuc_2_N PF07582.12 EWM24078.1 - 0.0091 15.7 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 1 AP endonuclease family 2 C terminus Aldedh PF00171.22 EWM24081.1 - 4.8e-05 22.0 0.0 0.00013 20.7 0.0 1.6 1 1 0 1 1 1 1 Aldehyde dehydrogenase family SPX PF03105.19 EWM24082.1 - 0.00017 21.6 0.6 0.00025 21.1 0.6 1.2 1 0 0 1 1 1 1 SPX domain TPR_MLP1_2 PF07926.12 EWM24082.1 - 0.32 11.1 19.4 1.4 9.0 3.0 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein SAP130_C PF16014.5 EWM24082.1 - 2.3 7.2 12.6 3.8 6.5 12.6 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus DUF5572 PF17733.1 EWM24083.1 - 3.6e-06 26.7 3.0 6.2e-05 22.7 3.0 2.2 1 1 0 1 1 1 1 Family of unknown function (DUF5572) Pex14_N PF04695.13 EWM24084.1 - 3.9e-21 76.4 0.0 5.1e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase_Tyr PF07714.17 EWM24092.1 - 1.3e-06 27.9 0.0 1.5e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase CBFD_NFYB_HMF PF00808.23 EWM24094.1 - 1.9e-05 24.9 0.0 2.4e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone OxoGdeHyase_C PF16870.5 EWM24096.1 - 1e-24 86.9 0.0 3.3e-24 85.3 0.0 1.7 1 1 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal Transket_pyr PF02779.24 EWM24096.1 - 1.4e-09 37.9 0.1 1.8e-09 37.5 0.1 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Peptidase_S41 PF03572.18 EWM24100.1 - 1.2e-40 138.8 0.2 1.8e-40 138.2 0.2 1.3 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 EWM24100.1 - 7.4e-11 41.7 0.1 1.7e-10 40.5 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EWM24100.1 - 7.9e-10 39.0 0.1 1.7e-09 37.9 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EWM24100.1 - 1.5e-06 28.5 0.1 4.2e-06 27.0 0.1 1.7 1 0 0 1 1 1 1 PDZ domain SUV3_C PF12513.8 EWM24104.1 - 6.8e-14 51.5 0.1 1.9e-13 50.1 0.1 1.8 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 EWM24104.1 - 2.6e-09 37.4 0.0 7.1e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 EWM24104.1 - 1.4e-08 34.4 0.8 3.1e-08 33.4 0.8 1.6 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 Pkinase PF00069.25 EWM24105.1 - 2.7e-61 207.2 0.0 4e-61 206.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM24105.1 - 2.6e-38 131.8 0.0 3.5e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EWM24105.1 - 1.2e-07 30.9 2.0 1.8e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EWM24105.1 - 0.0019 17.6 0.0 0.0034 16.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like BSP_II PF05432.11 EWM24105.1 - 0.012 15.3 12.3 0.017 14.8 12.3 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) APH PF01636.23 EWM24105.1 - 0.018 15.0 0.6 0.018 15.0 0.6 3.2 2 2 0 2 2 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EWM24105.1 - 0.067 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Cwf_Cwc_15 PF04889.12 EWM24105.1 - 0.11 12.2 14.9 0.21 11.3 14.9 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TFIIA PF03153.13 EWM24105.1 - 0.32 11.0 6.8 0.43 10.5 6.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PPP4R2 PF09184.11 EWM24105.1 - 1.7 8.2 12.2 2.9 7.4 12.2 1.3 1 0 0 1 1 1 0 PPP4R2 DNA_pol_phi PF04931.13 EWM24105.1 - 6.5 4.7 15.2 11 4.0 15.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi F-box-like PF12937.7 EWM24106.1 - 0.0021 17.9 1.1 0.0054 16.6 1.1 1.8 1 0 0 1 1 1 1 F-box-like Cupin_3 PF05899.12 EWM24108.1 - 1.9e-07 30.7 0.5 3.4e-07 29.8 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) SNARE_assoc PF09335.11 EWM24111.1 - 0.0065 16.9 1.9 0.0078 16.7 0.6 1.7 2 0 0 2 2 2 1 SNARE associated Golgi protein APH PF01636.23 EWM24112.1 - 3.2e-07 30.5 0.3 0.0072 16.3 0.2 2.6 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 EWM24112.1 - 1.1e-06 28.3 0.0 1.7e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM24112.1 - 0.00051 19.4 0.0 0.00085 18.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3437 PF11919.8 EWM24112.1 - 0.055 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) SNARE_assoc PF09335.11 EWM24113.1 - 0.15 12.6 1.1 1 9.9 0.2 2.2 2 0 0 2 2 2 0 SNARE associated Golgi protein Rubredoxin PF00301.20 EWM24114.1 - 6.4e-13 48.5 5.9 1e-12 47.8 5.9 1.3 1 0 0 1 1 1 1 Rubredoxin Spherulin4 PF12138.8 EWM24114.1 - 0.081 12.5 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Spherulation-specific family 4 HypA PF01155.19 EWM24114.1 - 0.098 12.7 0.1 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Elf1 PF05129.13 EWM24114.1 - 0.13 12.3 1.5 9.2 6.4 0.1 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like TF_Zn_Ribbon PF08271.12 EWM24114.1 - 0.33 10.5 1.9 11 5.7 0.5 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding zf-Mss51 PF13824.6 EWM24114.1 - 0.66 10.1 3.5 11 6.2 1.0 2.7 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Rubredoxin_2 PF18073.1 EWM24114.1 - 8.9 6.1 9.4 2.7 7.8 1.5 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain Rieske_2 PF13806.6 EWM24115.1 - 0.00029 20.7 0.0 0.00048 20.0 0.0 1.4 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.26 EWM24115.1 - 0.034 14.1 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain zinc_ribbon_4 PF13717.6 EWM24115.1 - 0.15 12.0 0.2 0.82 9.7 0.0 2.0 2 0 0 2 2 2 0 zinc-ribbon domain Zn-C2H2_12 PF18112.1 EWM24115.1 - 0.19 12.3 0.1 0.39 11.2 0.1 1.5 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain PMSR PF01625.21 EWM24116.1 - 1e-24 87.4 0.2 1.8e-24 86.7 0.2 1.3 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase PMSR PF01625.21 EWM24117.1 - 2.9e-62 209.4 0.3 4.4e-62 208.8 0.3 1.2 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Pyr_redox_2 PF07992.14 EWM24119.1 - 3.2e-06 26.6 0.0 4.3e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EWM24119.1 - 0.0038 17.2 0.0 0.01 15.8 0.0 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding CDC45 PF02724.14 EWM24125.1 - 0.0095 14.3 16.0 0.01 14.2 16.0 1.0 1 0 0 1 1 1 1 CDC45-like protein BSP_II PF05432.11 EWM24125.1 - 0.031 14.0 20.8 0.038 13.7 20.8 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Nop14 PF04147.12 EWM24125.1 - 0.031 12.5 19.1 0.034 12.4 19.1 1.0 1 0 0 1 1 1 0 Nop14-like family RNA_pol_Rpc4 PF05132.14 EWM24125.1 - 0.042 14.3 1.6 0.047 14.1 1.6 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Mpp10 PF04006.12 EWM24125.1 - 0.068 11.6 16.8 0.074 11.5 16.8 1.1 1 0 0 1 1 1 0 Mpp10 protein RPA43_OB PF17875.1 EWM24125.1 - 0.083 13.5 5.5 0.11 13.1 5.5 1.3 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I BUD22 PF09073.10 EWM24125.1 - 0.16 11.3 13.7 0.16 11.3 13.7 1.1 1 0 0 1 1 1 0 BUD22 CobT PF06213.12 EWM24125.1 - 0.18 11.2 17.6 0.24 10.8 17.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SDA1 PF05285.12 EWM24125.1 - 0.2 11.0 20.0 0.22 10.9 20.0 1.1 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 EWM24125.1 - 0.21 10.8 21.5 0.29 10.4 21.5 1.1 1 0 0 1 1 1 0 NOA36 protein Radial_spoke PF04712.12 EWM24125.1 - 0.41 9.5 17.0 0.48 9.3 17.0 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Paf1 PF03985.13 EWM24125.1 - 0.55 9.2 21.9 0.67 8.9 21.9 1.1 1 0 0 1 1 1 0 Paf1 Presenilin PF01080.17 EWM24125.1 - 0.61 8.8 2.3 0.55 8.9 2.3 1.1 1 0 0 1 1 1 0 Presenilin RNA_pol_3_Rpc31 PF11705.8 EWM24125.1 - 0.84 9.8 23.5 1.3 9.3 23.5 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RPN2_C PF18004.1 EWM24125.1 - 1.3 9.0 10.0 1.6 8.7 10.0 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Sporozoite_P67 PF05642.11 EWM24125.1 - 1.4 7.0 9.2 1.7 6.6 9.2 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NPR3 PF03666.13 EWM24125.1 - 1.6 7.4 2.7 1.7 7.4 2.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Connexin PF00029.19 EWM24125.1 - 1.7 8.3 3.1 2 8.1 3.1 1.1 1 0 0 1 1 1 0 Connexin MRNIP PF15749.5 EWM24125.1 - 1.8 9.3 5.9 1.8 9.3 5.1 1.5 2 0 0 2 2 1 0 MRN-interacting protein DUF2722 PF10846.8 EWM24125.1 - 2.3 7.1 7.7 2.6 6.9 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) THOC2_N PF16134.5 EWM24125.1 - 2.4 6.7 5.3 2.6 6.6 5.3 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus GRP PF07172.11 EWM24125.1 - 4 8.2 12.0 7.2 7.4 12.0 1.4 1 1 0 1 1 1 0 Glycine rich protein family DUF913 PF06025.12 EWM24125.1 - 4.8 6.0 5.0 5.3 5.9 5.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Spore_coat_CotO PF14153.6 EWM24125.1 - 6.1 6.7 12.1 7.4 6.5 12.1 1.1 1 0 0 1 1 1 0 Spore coat protein CotO TFIIF_alpha PF05793.12 EWM24125.1 - 6.4 5.2 24.6 7.3 5.1 24.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RRN3 PF05327.11 EWM24125.1 - 6.5 5.2 13.8 6.9 5.1 13.8 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4637 PF15470.6 EWM24125.1 - 6.9 6.4 18.0 9.7 5.9 18.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF3402 PF11882.8 EWM24125.1 - 7.3 5.6 8.8 9.2 5.2 8.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) Peptidase_C1 PF00112.23 EWM24126.1 - 0.0065 16.6 0.0 0.0079 16.3 0.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease CytB6-F_Fe-S PF08802.10 EWM24127.1 - 0.13 12.3 0.8 0.23 11.5 0.8 1.3 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit DUF1966 PF09260.11 EWM24127.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1966) Ribosomal_L28e PF01778.17 EWM24128.1 - 4.2e-26 92.0 0.3 5.4e-26 91.6 0.3 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Transglut_core PF01841.19 EWM24130.1 - 0.01 16.3 0.0 0.018 15.5 0.0 1.5 1 1 0 1 1 1 0 Transglutaminase-like superfamily CDC45 PF02724.14 EWM24130.1 - 0.29 9.4 2.2 0.27 9.5 1.4 1.3 2 0 0 2 2 2 0 CDC45-like protein Methyltransf_25 PF13649.6 EWM24131.1 - 1e-09 39.0 0.0 3.2e-09 37.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM24131.1 - 2.5e-08 34.4 0.0 6.2e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EWM24131.1 - 1.9e-07 31.7 0.0 3.3e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EWM24131.1 - 1.9e-06 27.8 0.0 9.2e-06 25.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 EWM24131.1 - 0.00021 21.3 0.1 0.0015 18.5 0.1 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_32 PF13679.6 EWM24131.1 - 0.012 15.6 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 EWM24131.1 - 0.026 13.8 0.0 0.039 13.3 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF938 PF06080.12 EWM24131.1 - 0.035 13.9 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) CheR PF01739.18 EWM24131.1 - 0.13 11.7 0.0 0.43 10.0 0.0 1.8 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_15 PF09445.10 EWM24131.1 - 0.21 11.2 0.0 0.33 10.5 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Fis1_TPR_C PF14853.6 EWM24132.1 - 1e-06 28.7 0.2 1.8e-06 27.9 0.2 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 EWM24132.1 - 3.4e-06 27.2 2.0 0.0046 17.2 0.1 1.6 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EWM24132.1 - 6.3e-05 22.8 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 EWM24132.1 - 0.005 17.3 0.8 0.0077 16.7 0.0 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat SKG6 PF08693.10 EWM24132.1 - 0.012 15.1 1.3 0.021 14.3 1.3 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TPR_6 PF13174.6 EWM24132.1 - 0.013 16.1 0.0 0.033 14.8 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Prenyltrans PF00432.21 EWM24136.1 - 3.7e-27 93.7 5.4 1e-12 47.6 0.2 3.1 3 0 0 3 3 3 2 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 EWM24136.1 - 0.03 13.4 0.1 0.33 10.0 0.0 1.9 1 1 1 2 2 2 0 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EWM24136.1 - 0.14 11.3 0.0 2.8 6.9 0.0 2.1 1 1 1 2 2 2 0 Squalene-hopene cyclase N-terminal domain AAA PF00004.29 EWM24137.1 - 7.2e-11 42.6 0.0 1e-10 42.2 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EWM24137.1 - 6e-08 32.6 0.0 0.011 15.5 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 EWM24137.1 - 3.4e-07 30.4 0.0 9.8e-07 28.9 0.0 1.7 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 EWM24137.1 - 6.2e-06 26.5 0.9 0.043 14.1 0.1 2.2 1 1 1 2 2 2 2 AAA domain AAA_11 PF13086.6 EWM24137.1 - 2.5e-05 24.2 0.1 5.5e-05 23.1 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EWM24137.1 - 2.8e-05 24.6 0.1 8.1e-05 23.1 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EWM24137.1 - 4.1e-05 23.4 0.0 5.1e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 EWM24137.1 - 6.8e-05 22.9 0.1 0.068 13.2 0.0 2.1 1 1 1 2 2 2 2 Type III restriction enzyme, res subunit AAA_3 PF07726.11 EWM24137.1 - 0.00023 21.0 0.0 0.00033 20.5 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 EWM24137.1 - 0.00026 21.0 0.0 0.00032 20.7 0.0 1.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EWM24137.1 - 0.00039 20.2 0.0 0.00066 19.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EWM24137.1 - 0.00044 20.0 0.0 0.00068 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EWM24137.1 - 0.00046 20.2 0.0 0.00064 19.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EWM24137.1 - 0.00056 19.5 0.0 0.00085 18.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region TniB PF05621.11 EWM24137.1 - 0.00056 19.4 0.1 0.026 14.0 0.0 2.1 1 1 1 2 2 2 1 Bacterial TniB protein DUF815 PF05673.13 EWM24137.1 - 0.0006 19.1 0.0 0.00073 18.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 EWM24137.1 - 0.00094 19.2 0.1 0.0079 16.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 EWM24137.1 - 0.0014 19.0 0.2 0.015 15.6 0.2 2.0 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EWM24137.1 - 0.002 18.0 0.5 0.017 14.9 0.1 2.0 1 1 1 2 2 2 1 DEAD/DEAH box helicase TIP49 PF06068.13 EWM24137.1 - 0.017 14.4 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 EWM24137.1 - 0.017 14.9 0.1 0.033 13.9 0.1 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.16 EWM24137.1 - 0.018 14.5 0.0 0.31 10.5 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.21 EWM24137.1 - 0.044 13.2 0.2 0.28 10.6 0.1 2.1 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI PsbP PF01789.16 EWM24138.1 - 7.8e-24 84.6 0.0 4.8e-17 62.5 0.0 2.1 2 0 0 2 2 2 2 PsbP START PF01852.19 EWM24139.1 - 0.0024 17.3 0.0 0.0044 16.4 0.0 1.4 1 0 0 1 1 1 1 START domain Sulfate_transp PF00916.20 EWM24140.1 - 3e-69 233.6 9.9 4.1e-69 233.2 9.9 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EWM24140.1 - 1.3e-11 44.1 0.0 2.8e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EWM24140.1 - 0.0023 18.3 1.0 0.0023 18.3 1.0 3.1 4 0 0 4 4 4 1 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 EWM24140.1 - 0.0074 16.6 2.4 0.011 16.1 0.8 2.1 2 0 0 2 2 2 1 STAS domain Sulfate_transp PF00916.20 EWM24141.1 - 2.1e-69 234.1 9.9 2.8e-69 233.7 9.9 1.1 1 0 0 1 1 1 1 Sulfate permease family MFS_MOT1 PF16983.5 EWM24141.1 - 0.0018 18.6 1.0 0.0018 18.6 1.0 3.1 4 0 0 4 4 4 1 Molybdate transporter of MFS superfamily STAS PF01740.21 EWM24141.1 - 0.2 11.3 0.0 0.4 10.3 0.0 1.4 1 0 0 1 1 1 0 STAS domain ACT_3 PF10000.9 EWM24142.1 - 0.2 11.6 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 ACT domain HemY_N PF07219.13 EWM24143.1 - 0.00045 20.4 1.2 0.00075 19.7 1.2 1.4 1 1 0 1 1 1 1 HemY protein N-terminus SepA PF17080.5 EWM24143.1 - 0.043 14.2 0.1 0.049 14.0 0.1 1.1 1 0 0 1 1 1 0 Multidrug Resistance efflux pump Lipase_3 PF01764.25 EWM24145.1 - 2.1e-10 40.6 0.0 3.7e-09 36.6 0.0 2.2 1 1 1 2 2 2 1 Lipase (class 3) VitD-bind_III PF09164.10 EWM24146.1 - 0.19 11.8 0.1 0.59 10.2 0.0 1.8 2 0 0 2 2 2 0 Vitamin D binding protein, domain III Mod_r PF07200.13 EWM24147.1 - 1.8e-21 76.8 3.5 6.9e-21 74.9 3.5 1.7 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein EzrA PF06160.12 EWM24147.1 - 0.012 13.8 0.2 0.016 13.4 0.2 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA SpoIISA_toxin PF14171.6 EWM24147.1 - 0.18 11.5 0.4 0.25 11.0 0.4 1.2 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system DUF599 PF04654.12 EWM24149.1 - 5.6e-08 32.5 1.8 8e-08 32.0 1.8 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF599 DUF2526 PF10735.9 EWM24151.1 - 1.7 8.8 5.4 1.3 9.2 3.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2526) Acyl-CoA_dh_N PF02771.16 EWM24154.1 - 5.9e-40 136.5 0.0 1.1e-39 135.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EWM24154.1 - 1.9e-14 53.6 0.1 3.9e-14 52.6 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DsbB PF02600.16 EWM24155.1 - 0.015 15.8 0.0 0.24 11.8 0.0 2.0 1 1 0 1 1 1 0 Disulfide bond formation protein DsbB Ysc84 PF04366.12 EWM24157.1 - 3.9e-19 68.7 0.0 5.7e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Las17-binding protein actin regulator VID27_N PF17748.1 EWM24157.1 - 1.3 8.8 7.9 2.1 8.2 7.9 1.2 1 0 0 1 1 1 0 VID27 N-terminal region CDC45 PF02724.14 EWM24157.1 - 9.9 4.3 9.2 11 4.2 9.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Ubie_methyltran PF01209.18 EWM24158.1 - 3.7e-77 258.8 0.0 4.6e-77 258.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 EWM24158.1 - 5.3e-17 62.3 0.0 1.2e-16 61.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM24158.1 - 1.1e-15 58.1 0.0 2.2e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM24158.1 - 6.5e-12 45.5 0.0 1.2e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EWM24158.1 - 5.3e-07 29.6 0.0 7.4e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EWM24158.1 - 4.6e-06 27.3 0.0 9.8e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EWM24158.1 - 0.2 11.5 0.0 0.45 10.3 0.0 1.6 2 0 0 2 2 2 0 Hypothetical methyltransferase SOG2 PF10428.9 EWM24158.1 - 0.31 10.2 7.2 0.4 9.8 7.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PAP1 PF08601.10 EWM24158.1 - 3.4 7.3 17.9 4.7 6.9 17.9 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 SPX PF03105.19 EWM24158.1 - 3.5 7.5 6.6 4.6 7.1 6.6 1.1 1 0 0 1 1 1 0 SPX domain QWRF PF04484.12 EWM24158.1 - 6.5 6.4 6.9 9.9 5.8 6.9 1.3 1 0 0 1 1 1 0 QWRF family DUF1365 PF07103.11 EWM24159.1 - 2.1e-51 174.9 0.0 2.7e-51 174.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) NeA_P2 PF12312.8 EWM24159.1 - 0.054 12.9 1.1 0.094 12.2 1.1 1.3 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein TGT PF01702.18 EWM24160.1 - 6e-132 440.0 0.0 7.4e-132 439.7 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Glutaredoxin PF00462.24 EWM24161.1 - 1.3e-16 60.5 0.0 2e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin PepSY_2 PF13670.6 EWM24162.1 - 0.0073 16.3 0.1 0.013 15.5 0.1 1.4 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain PepSY_2 PF13670.6 EWM24163.1 - 0.016 15.2 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain HlyIII PF03006.20 EWM24164.1 - 3.9e-21 75.8 9.6 4.5e-21 75.6 9.6 1.0 1 0 0 1 1 1 1 Haemolysin-III related Ceramidase PF05875.12 EWM24164.1 - 0.0017 17.8 5.3 0.0022 17.5 5.3 1.1 1 0 0 1 1 1 1 Ceramidase Kazal_1 PF00050.21 EWM24165.1 - 6.5e-20 70.9 20.9 5.3e-07 29.5 1.5 3.6 3 0 0 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 EWM24165.1 - 1.3e-10 41.2 17.6 0.0003 20.8 2.1 3.5 3 0 0 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 EWM24166.1 - 1.5e-19 69.8 24.6 6.9e-07 29.2 1.5 3.9 4 0 0 4 4 4 3 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 EWM24166.1 - 9.3e-09 35.3 25.2 0.00039 20.5 2.1 4.2 4 0 0 4 4 4 3 Kazal-type serine protease inhibitor domain Nodulin_late PF07127.11 EWM24166.1 - 2.6 8.5 6.3 0.28 11.5 0.4 2.4 2 1 1 3 3 3 0 Late nodulin protein MFS_1 PF07690.16 EWM24167.1 - 3.5e-19 68.9 31.0 2.9e-18 65.9 31.1 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EWM24167.1 - 0.071 12.0 1.7 1.4 7.7 4.5 1.6 2 0 0 2 2 2 0 MFS_1 like family OATP PF03137.20 EWM24167.1 - 6.4 4.9 6.8 9.9 4.3 0.7 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family HlyIII PF03006.20 EWM24168.1 - 9.8e-15 54.9 4.0 1.5e-14 54.3 4.0 1.2 1 0 0 1 1 1 1 Haemolysin-III related Ank_2 PF12796.7 EWM24172.1 - 8e-23 80.8 0.0 1.4e-09 38.4 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EWM24172.1 - 3e-19 68.5 0.3 6.4e-05 23.2 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EWM24172.1 - 3.6e-18 65.4 0.3 9.8e-06 25.7 0.0 4.8 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EWM24172.1 - 4.8e-17 60.3 0.1 0.0098 16.3 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 EWM24172.1 - 1.1e-14 54.5 0.1 4.8e-07 30.2 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeats (many copies) RII_binding_1 PF10522.9 EWM24173.1 - 0.14 12.4 0.7 0.37 11.1 0.7 1.7 1 0 0 1 1 1 0 RII binding domain DXPR_C PF13288.6 EWM24174.1 - 4e-15 56.1 0.2 4.6e-15 55.9 0.2 1.1 1 0 0 1 1 1 1 DXP reductoisomerase C-terminal domain Phage_30_8 PF06019.11 EWM24174.1 - 0.047 13.6 0.2 0.065 13.1 0.2 1.3 1 1 0 1 1 1 0 Phage GP30.8 protein DXP_reductoisom PF02670.16 EWM24175.1 - 1.8e-10 41.6 0.0 3e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Peptidase_M50 PF02163.22 EWM24176.1 - 7e-05 22.2 0.0 9e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M50 DUF1275 PF06912.11 EWM24177.1 - 1.2e-13 51.5 4.7 1.7e-13 50.9 4.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) HSF_DNA-bind PF00447.17 EWM24178.1 - 2.1e-27 95.6 0.1 3.4e-27 94.9 0.1 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Chal_sti_synt_C PF02797.15 EWM24178.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain Acetyltransf_3 PF13302.7 EWM24181.1 - 2.8e-24 86.4 0.0 8.2e-24 84.8 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EWM24181.1 - 1.3e-10 41.5 0.0 2e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 EWM24181.1 - 6.5e-10 38.9 0.0 9.6e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EWM24181.1 - 4e-05 23.5 0.0 6.9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EWM24181.1 - 0.0015 18.7 0.0 0.003 17.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DEAD PF00270.29 EWM24183.1 - 9.7e-33 113.4 0.0 1.6e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EWM24183.1 - 7e-23 81.1 0.0 3.4e-22 78.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EWM24183.1 - 0.00012 22.2 0.0 0.00018 21.5 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.14 EWM24183.1 - 0.0077 15.1 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer AAA_22 PF13401.6 EWM24183.1 - 0.014 15.7 0.0 0.047 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain Peptidase_S64 PF08192.11 EWM24184.1 - 0.23 9.9 11.3 0.23 9.9 11.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 TMEM151 PF14857.6 EWM24184.1 - 1.6 7.6 4.4 1.8 7.4 4.4 1.1 1 0 0 1 1 1 0 TMEM151 family AAR2 PF05282.11 EWM24184.1 - 2.3 7.5 8.2 2.3 7.6 8.2 1.2 1 0 0 1 1 1 0 AAR2 protein DUF3807 PF12720.7 EWM24184.1 - 3.7 7.8 14.5 4.2 7.6 14.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Gti1_Pac2 PF09729.9 EWM24184.1 - 3.9 7.5 19.1 4.3 7.4 19.1 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Dapper PF15268.6 EWM24184.1 - 4.2 6.1 11.2 4 6.2 11.2 1.0 1 0 0 1 1 1 0 Dapper Pex14_N PF04695.13 EWM24184.1 - 5.5 7.6 6.4 6.3 7.4 6.4 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Zip PF02535.22 EWM24184.1 - 6.8 5.8 12.0 6.3 5.9 12.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter NST1 PF13945.6 EWM24184.1 - 7 6.7 37.8 8.6 6.4 37.8 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Presenilin PF01080.17 EWM24184.1 - 9.7 4.8 17.1 10 4.8 17.1 1.0 1 0 0 1 1 1 0 Presenilin Pkinase PF00069.25 EWM24185.1 - 8.3e-66 222.1 0.0 1.2e-65 221.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM24185.1 - 1e-32 113.5 0.0 1.3e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EWM24185.1 - 1.5e-07 31.1 0.0 3.4e-07 29.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EWM24185.1 - 4e-06 26.3 0.0 7.9e-06 25.4 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EWM24185.1 - 6e-05 22.0 0.0 0.00012 21.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EWM24185.1 - 0.0086 16.0 0.0 0.021 14.8 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EWM24185.1 - 0.009 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.9 EWM24185.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Phasin PF05597.11 EWM24185.1 - 0.11 12.5 0.1 0.39 10.7 0.0 1.8 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Choline_kinase PF01633.20 EWM24185.1 - 0.16 11.5 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 EWM24185.1 - 0.18 11.4 0.2 0.36 10.4 0.0 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PAH PF02671.21 EWM24186.1 - 8.5e-68 224.3 0.3 2.5e-10 40.3 0.0 6.7 6 0 0 6 6 6 6 Paired amphipathic helix repeat YlbD_coat PF14071.6 EWM24186.1 - 0.076 13.3 0.6 0.28 11.5 0.6 1.9 1 0 0 1 1 1 0 Putative coat protein PAH PF02671.21 EWM24187.1 - 6.6e-68 224.6 0.3 2.4e-10 40.4 0.0 6.6 6 0 0 6 6 6 6 Paired amphipathic helix repeat YlbD_coat PF14071.6 EWM24187.1 - 0.068 13.4 0.6 0.26 11.6 0.6 1.9 1 0 0 1 1 1 0 Putative coat protein MinC_C PF03775.16 EWM24189.1 - 7.5e-24 83.7 2.4 1.3e-23 82.9 2.4 1.3 1 0 0 1 1 1 1 Septum formation inhibitor MinC, C-terminal domain FapA PF03961.13 EWM24189.1 - 9.6e-05 21.2 1.2 0.00013 20.7 1.2 1.1 1 0 0 1 1 1 1 Flagellar Assembly Protein A MinC_N PF05209.13 EWM24189.1 - 0.043 13.8 0.0 0.26 11.3 0.0 1.9 2 0 0 2 2 2 0 Septum formation inhibitor MinC, N-terminal domain DUF2407_C PF13373.6 EWM24189.1 - 0.19 11.9 0.0 0.32 11.2 0.0 1.3 1 0 0 1 1 1 0 DUF2407 C-terminal domain FAP PF07174.11 EWM24189.1 - 7.4 5.9 31.8 0.29 10.6 19.2 2.5 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) TauD PF02668.16 EWM24190.1 - 2.1e-40 139.2 0.1 3.4e-40 138.5 0.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EWM24190.1 - 3.4e-10 40.4 0.0 0.00071 20.2 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF971) CsiD PF08943.10 EWM24190.1 - 0.0013 18.0 0.0 0.0023 17.1 0.0 1.4 1 0 0 1 1 1 1 CsiD CorA PF01544.18 EWM24191.1 - 3.5e-11 42.9 3.1 1.6e-10 40.8 3.0 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein XRCC1_N PF01834.16 EWM24192.1 - 0.12 12.4 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 XRCC1 N terminal domain C2 PF00168.30 EWM24193.1 - 6.3e-08 32.8 0.0 1.3e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain Abhydrolase_6 PF12697.7 EWM24194.1 - 2.1e-14 54.7 7.5 2.1e-14 54.7 7.5 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EWM24194.1 - 1.8e-05 24.2 0.2 0.28 10.4 0.0 2.9 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 EWM24194.1 - 0.0017 18.5 0.0 0.0047 17.0 0.0 1.7 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.20 EWM24194.1 - 0.004 16.9 0.0 0.97 9.0 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EWM24194.1 - 0.011 15.3 0.0 0.025 14.1 0.0 1.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family FSH1 PF03959.13 EWM24194.1 - 0.076 12.7 0.0 0.43 10.2 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase (FSH1) LIDHydrolase PF10230.9 EWM24194.1 - 0.2 11.2 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Fer2 PF00111.27 EWM24195.1 - 1.2e-07 31.6 0.2 2.2e-07 30.7 0.2 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain CvfB_WH PF17783.1 EWM24196.1 - 2.8e-14 52.7 0.0 4.4e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 CvfB-like winged helix domain SAP PF02037.27 EWM24196.1 - 9.3e-10 38.0 1.3 1.6e-09 37.3 1.3 1.4 1 0 0 1 1 1 1 SAP domain S1 PF00575.23 EWM24196.1 - 6.1e-07 29.7 0.3 1.2e-06 28.8 0.3 1.5 1 0 0 1 1 1 1 S1 RNA binding domain RRM_1 PF00076.22 EWM24196.1 - 0.0011 18.8 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5551 PF17705.1 EWM24196.1 - 0.066 12.8 0.0 0.21 11.2 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5551) RRM_7 PF16367.5 EWM24196.1 - 0.14 12.3 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif DGF-1_5 PF11038.8 EWM24196.1 - 0.32 10.3 1.4 0.54 9.5 0.2 1.9 2 1 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 5 DUF1899 PF08953.11 EWM24197.1 - 3.7e-21 74.8 0.1 6.9e-21 73.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 EWM24197.1 - 1.3e-16 60.2 0.2 2.2e-16 59.5 0.2 1.4 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 EWM24197.1 - 4e-15 55.9 2.0 2.4e-05 25.0 0.3 4.8 4 1 1 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM24197.1 - 1.2e-05 25.5 0.1 0.0059 16.9 0.1 3.6 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EWM24197.1 - 0.014 14.1 0.1 0.77 8.3 0.0 2.6 1 1 1 2 2 2 0 Nucleoporin Nup120/160 K_channel_TID PF07941.11 EWM24197.1 - 0.085 13.3 0.0 0.28 11.7 0.0 1.8 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain HMMR_C PF15908.5 EWM24198.1 - 0.00032 21.0 7.8 0.00032 21.0 7.8 2.3 1 1 1 2 2 2 1 Hyaluronan mediated motility receptor C-terminal Serine_rich PF08824.10 EWM24198.1 - 0.007 16.4 1.5 0.007 16.4 1.5 3.1 1 1 2 3 3 3 1 Serine rich protein interaction domain Tropomyosin_1 PF12718.7 EWM24198.1 - 0.016 15.4 40.3 0.32 11.2 8.7 3.2 1 1 2 3 3 3 0 Tropomyosin like YuzL PF14115.6 EWM24198.1 - 0.44 11.1 4.6 0.28 11.7 0.5 2.4 2 0 0 2 2 2 0 YuzL-like protein TSC22 PF01166.18 EWM24198.1 - 0.58 10.5 9.3 0.17 12.2 0.9 3.6 3 1 1 4 4 4 0 TSC-22/dip/bun family bZIP_1 PF00170.21 EWM24198.1 - 8.3 6.6 16.8 3.9 7.6 2.3 3.9 3 1 2 5 5 5 0 bZIP transcription factor Mito_carr PF00153.27 EWM24200.1 - 2.4e-24 85.1 0.4 1.8e-12 47.0 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Homoserine_dh PF00742.19 EWM24201.1 - 2.7e-55 186.9 0.0 5e-55 186.1 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 EWM24201.1 - 6.4e-13 49.4 0.1 1.2e-12 48.6 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Pkinase PF00069.25 EWM24202.1 - 4.8e-38 131.0 0.0 5.9e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM24202.1 - 1.6e-23 83.4 0.0 2.1e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EWM24202.1 - 2.6e-06 27.0 0.0 3.8e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EWM24202.1 - 0.065 12.2 0.0 0.095 11.6 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 EWM24202.1 - 0.17 10.6 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EWM24202.1 - 0.18 11.7 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Myosin_head PF00063.21 EWM24203.1 - 4.3e-195 649.8 0.0 5.4e-151 504.1 0.0 2.1 2 0 0 2 2 2 2 Myosin head (motor domain) IQ PF00612.27 EWM24203.1 - 0.0025 17.4 24.0 0.017 14.9 4.0 4.2 4 0 0 4 4 4 2 IQ calmodulin-binding motif DUF87 PF01935.17 EWM24203.1 - 0.0056 16.8 0.7 0.7 9.9 0.2 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain DLIC PF05783.11 EWM24203.1 - 0.032 13.1 0.3 0.38 9.5 0.0 2.7 3 0 0 3 3 3 0 Dynein light intermediate chain (DLIC) AAA_22 PF13401.6 EWM24203.1 - 0.053 13.8 1.7 0.12 12.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 EWM24203.1 - 0.068 13.1 0.1 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 EWM24203.1 - 0.14 12.6 0.0 0.5 10.9 0.0 1.9 1 0 0 1 1 1 0 ABC transporter CbiA PF01656.23 EWM24203.1 - 0.2 11.7 0.6 0.54 10.3 0.1 1.9 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 EWM24203.1 - 0.63 9.7 3.7 0.41 10.3 0.7 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EWM24203.1 - 0.65 10.4 0.0 0.65 10.4 0.0 2.7 3 1 0 3 3 3 0 AAA ATPase domain Kinesin PF00225.23 EWM24204.1 - 1.6e-104 349.4 0.0 2.7e-104 348.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EWM24204.1 - 9.5e-22 77.5 0.0 2.3e-21 76.3 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding DEAD PF00270.29 EWM24204.1 - 0.092 12.5 0.0 0.22 11.3 0.0 1.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase DTW PF03942.15 EWM24207.1 - 9.9e-31 107.0 0.0 1.5e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 DTW domain SfsA_N PF17746.1 EWM24207.1 - 0.039 14.1 0.0 0.16 12.1 0.0 2.1 2 0 0 2 2 2 0 SfsA N-terminal OB domain PBP1_TM PF14812.6 EWM24207.1 - 0.68 10.4 4.4 1.9 8.9 4.4 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ndc80_HEC PF03801.13 EWM24208.1 - 6.7e-44 149.2 0.1 1.2e-43 148.4 0.1 1.4 1 0 0 1 1 1 1 HEC/Ndc80p family Phage_GP20 PF06810.11 EWM24208.1 - 0.0011 18.8 17.4 0.042 13.7 1.9 3.4 2 1 1 3 3 3 2 Phage minor structural protein GP20 DUF4164 PF13747.6 EWM24208.1 - 0.018 15.3 3.8 0.018 15.3 3.8 4.6 3 2 1 4 4 4 0 Domain of unknown function (DUF4164) HBS1_N PF08938.10 EWM24208.1 - 0.019 15.2 2.7 0.019 15.2 2.7 3.2 3 2 1 4 4 3 0 HBS1 N-terminus Fez1 PF06818.15 EWM24208.1 - 0.024 15.1 25.0 0.21 12.0 6.1 2.2 2 0 0 2 2 2 0 Fez1 DUF3584 PF12128.8 EWM24208.1 - 0.036 11.6 26.4 0.022 12.3 7.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Bacillus_HBL PF05791.11 EWM24208.1 - 0.069 13.0 4.0 0.31 10.8 1.6 2.7 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Fib_alpha PF08702.10 EWM24208.1 - 0.073 13.2 5.2 4.7 7.4 1.7 2.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 EWM24208.1 - 0.26 10.6 23.1 0.24 10.7 7.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) DUF802 PF05650.11 EWM24208.1 - 0.29 11.7 2.8 31 5.1 0.2 3.5 2 0 0 2 2 2 0 Domain of unknown function (DUF802) BLOC1_2 PF10046.9 EWM24208.1 - 0.82 10.0 15.2 1.6 9.1 0.1 4.4 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 V_ATPase_I PF01496.19 EWM24208.1 - 1 7.2 13.3 1.4 6.8 12.4 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_13 PF13166.6 EWM24208.1 - 2.2 6.9 20.2 2e+02 0.4 20.1 2.2 1 1 0 1 1 1 0 AAA domain FliJ PF02050.16 EWM24208.1 - 5 7.4 25.8 0.14 12.4 1.0 3.9 2 2 1 3 3 3 0 Flagellar FliJ protein FUSC PF04632.12 EWM24208.1 - 7.9 4.9 20.7 0.18 10.3 7.8 2.3 2 0 0 2 2 2 0 Fusaric acid resistance protein family ELMO_CED12 PF04727.13 EWM24209.1 - 4.9e-21 75.6 0.0 7.1e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family DIX PF00778.17 EWM24209.1 - 0.029 14.2 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 DIX domain Fungal_trans_2 PF11951.8 EWM24209.1 - 0.18 10.6 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain NAD_Gly3P_dh_C PF07479.14 EWM24210.1 - 2.7e-44 150.9 0.1 5e-44 150.0 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 EWM24210.1 - 1.4e-41 142.1 0.0 2.4e-41 141.3 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 EWM24210.1 - 2.9e-08 34.2 0.0 1.1e-07 32.3 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 EWM24210.1 - 8.4e-08 32.0 0.0 2e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 EWM24210.1 - 0.0038 17.1 0.0 0.016 15.1 0.0 1.9 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EWM24210.1 - 0.009 16.2 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_2 PF07992.14 EWM24210.1 - 0.059 12.6 0.0 0.35 10.0 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EWM24210.1 - 0.059 13.9 1.5 0.17 12.4 0.1 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase PDH PF02153.17 EWM24210.1 - 0.063 12.3 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase Bud13 PF09736.9 EWM24211.1 - 1.2e-44 152.2 10.0 1.2e-44 152.2 10.0 1.7 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex Bud13 PF09736.9 EWM24212.1 - 1.2e-44 152.2 10.0 1.2e-44 152.2 10.0 1.7 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex CBS PF00571.28 EWM24213.1 - 2e-25 89.0 3.7 6.2e-06 26.6 0.0 4.3 4 0 0 4 4 4 4 CBS domain ABC_tran PF00005.27 EWM24214.1 - 6.6e-47 159.5 0.0 2.5e-22 79.9 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EWM24214.1 - 1.1e-22 79.9 4.6 1.1e-22 79.9 4.6 2.8 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.6 EWM24214.1 - 8.8e-18 65.1 0.2 0.00023 21.1 0.0 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EWM24214.1 - 5.8e-09 36.7 1.9 0.0045 17.5 0.0 3.8 4 0 0 4 4 4 2 AAA domain SMC_N PF02463.19 EWM24214.1 - 1.3e-08 34.6 0.6 0.18 11.2 0.1 3.7 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EWM24214.1 - 3.3e-08 33.2 0.1 0.00089 19.0 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EWM24214.1 - 2.1e-05 24.5 0.6 0.041 13.8 0.0 2.8 3 0 0 3 3 3 2 RsgA GTPase AAA_15 PF13175.6 EWM24214.1 - 3.1e-05 23.9 0.3 0.058 13.1 0.0 3.3 4 0 0 4 4 4 2 AAA ATPase domain MMR_HSR1 PF01926.23 EWM24214.1 - 0.00018 21.6 0.8 0.073 13.2 0.0 3.3 3 1 0 3 3 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EWM24214.1 - 0.00022 21.5 0.2 0.018 15.3 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EWM24214.1 - 0.00023 21.4 0.3 0.97 9.6 0.1 3.0 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 EWM24214.1 - 0.00028 21.4 0.0 0.49 10.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EWM24214.1 - 0.0021 17.8 2.1 0.97 9.1 0.0 3.7 4 1 0 4 4 4 1 AAA domain AAA_16 PF13191.6 EWM24214.1 - 0.0025 18.2 0.1 0.67 10.3 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 EWM24214.1 - 0.0034 17.1 0.0 1.3 8.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.17 EWM24214.1 - 0.0037 17.4 4.5 1.3 9.1 0.2 3.9 3 1 1 4 4 4 1 Helicase HerA, central domain SbcCD_C PF13558.6 EWM24214.1 - 0.0046 17.2 0.2 0.63 10.3 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA PF00004.29 EWM24214.1 - 0.0047 17.4 0.0 1 9.8 0.1 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MukB PF04310.12 EWM24214.1 - 0.0053 16.6 1.0 1.1 9.0 0.0 3.1 3 0 0 3 3 3 1 MukB N-terminal Dynamin_N PF00350.23 EWM24214.1 - 0.011 15.8 0.2 10 6.1 0.1 3.2 2 1 1 3 3 3 0 Dynamin family AAA_27 PF13514.6 EWM24214.1 - 0.018 14.7 0.7 1.9 8.0 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 EWM24214.1 - 0.02 14.9 0.0 1.4 8.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EWM24214.1 - 0.027 14.7 0.6 3.6 7.8 0.1 2.8 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EWM24214.1 - 0.033 14.6 0.0 3.7 8.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 EWM24214.1 - 0.036 13.3 0.0 7.3 5.7 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain AAA_17 PF13207.6 EWM24214.1 - 0.051 14.0 0.2 9 6.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain CLP1_P PF16575.5 EWM24214.1 - 0.08 12.7 0.0 43 3.8 0.0 3.6 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NACHT PF05729.12 EWM24214.1 - 0.08 12.8 0.3 1.7 8.5 0.0 2.6 2 0 0 2 2 2 0 NACHT domain G-alpha PF00503.20 EWM24214.1 - 0.088 12.0 0.0 11 5.0 0.0 2.4 2 1 0 2 2 2 0 G-protein alpha subunit AAA_13 PF13166.6 EWM24214.1 - 0.098 11.3 3.9 14 4.2 0.1 3.9 4 0 0 4 4 4 0 AAA domain AAA_7 PF12775.7 EWM24214.1 - 0.12 11.9 0.1 13 5.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region VIT1 PF01988.19 EWM24214.1 - 0.16 11.8 0.0 11 5.8 0.0 3.0 3 0 0 3 3 3 0 VIT family MeaB PF03308.16 EWM24214.1 - 0.26 10.2 2.4 13 4.7 0.0 3.2 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 EWM24214.1 - 0.47 10.2 2.8 21 4.8 0.0 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Adaptin_N PF01602.20 EWM24216.1 - 7.4e-90 302.0 0.0 9.3e-90 301.6 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EWM24216.1 - 3.4e-43 147.5 0.0 3.4e-42 144.2 0.0 2.4 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 EWM24216.1 - 7.3e-11 42.1 0.0 1.4e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 EWM24216.1 - 1e-10 41.8 0.2 0.014 15.8 0.0 4.9 2 2 2 5 5 5 5 HEAT repeats HEAT PF02985.22 EWM24216.1 - 3.6e-07 29.9 1.6 0.22 11.9 0.0 4.9 4 0 0 4 4 4 2 HEAT repeat RTP1_C1 PF10363.9 EWM24216.1 - 3.4e-06 27.2 0.0 0.037 14.2 0.0 3.0 2 0 0 2 2 2 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 EWM24216.1 - 0.0061 17.0 1.2 49 4.6 0.0 5.0 4 1 1 5 5 5 0 HEAT-like repeat Arm_2 PF04826.13 EWM24216.1 - 0.084 12.3 0.2 5.3 6.4 0.0 2.9 3 0 0 3 3 3 0 Armadillo-like Pro_isomerase PF00160.21 EWM24217.1 - 2.2e-46 158.0 0.0 3.4e-46 157.4 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PDZ PF00595.24 EWM24217.1 - 2.3e-10 40.7 0.2 3.7e-10 40.0 0.2 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EWM24217.1 - 2e-06 28.0 0.0 3.7e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EWM24217.1 - 1.3e-05 24.9 0.0 2.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain AA_permease_2 PF13520.6 EWM24218.1 - 7.2e-32 110.7 28.0 9e-32 110.4 28.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EWM24218.1 - 6.5e-17 61.3 20.7 9.3e-17 60.8 20.7 1.2 1 0 0 1 1 1 1 Amino acid permease TPPK_C PF12555.8 EWM24218.1 - 0.17 11.9 7.4 4 7.6 0.5 3.7 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal Aminotran_1_2 PF00155.21 EWM24220.1 - 1.8e-40 139.2 0.0 7.5e-40 137.2 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class I and II DnaJ_C PF01556.18 EWM24221.1 - 4.1e-39 134.0 0.1 5.7e-39 133.6 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EWM24221.1 - 7.2e-24 83.7 0.3 1.1e-23 83.1 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EWM24221.1 - 2.4e-14 53.5 18.7 4.4e-14 52.6 18.7 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EWM24221.1 - 0.0052 16.7 9.9 0.03 14.3 0.6 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EWM24221.1 - 9.6 6.3 8.1 20 5.2 1.7 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA GFO_IDH_MocA PF01408.22 EWM24222.1 - 1e-26 94.1 0.3 3.4e-26 92.4 0.2 1.9 3 0 0 3 3 3 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EWM24222.1 - 7.5e-10 38.8 0.0 1.4e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain CoA_binding PF02629.19 EWM24222.1 - 0.0015 19.2 0.4 0.004 17.8 0.4 1.7 1 0 0 1 1 1 1 CoA binding domain 2-Hacid_dh_C PF02826.19 EWM24222.1 - 0.0022 17.4 0.1 0.004 16.5 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EWM24222.1 - 0.007 16.9 0.3 0.021 15.4 0.2 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.20 EWM24222.1 - 0.015 15.4 0.4 0.19 11.9 0.2 2.4 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Gp_dh_N PF00044.24 EWM24222.1 - 0.045 14.1 0.7 0.16 12.3 0.4 2.1 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Redoxin PF08534.10 EWM24222.1 - 0.054 13.2 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Redoxin Aldo_ket_red PF00248.21 EWM24223.1 - 9.4e-21 74.3 0.0 3.9e-19 68.9 0.0 2.2 2 0 0 2 2 2 2 Aldo/keto reductase family Lipase_3 PF01764.25 EWM24225.1 - 6.3e-10 39.1 0.0 2e-09 37.5 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) MTHFR PF02219.17 EWM24226.1 - 1.3e-93 313.5 0.0 7.4e-93 311.0 0.0 1.8 1 1 0 1 1 1 1 Methylenetetrahydrofolate reductase HEAT_2 PF13646.6 EWM24228.1 - 1.5e-12 47.7 2.1 3.9e-05 24.0 0.0 4.0 2 2 0 2 2 2 2 HEAT repeats HEAT PF02985.22 EWM24228.1 - 3.1e-09 36.3 7.9 1 9.8 0.1 6.7 6 0 0 6 6 6 3 HEAT repeat Cnd1 PF12717.7 EWM24228.1 - 8.5e-07 29.1 0.4 0.017 15.2 0.0 3.6 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EWM24228.1 - 0.00046 18.9 0.4 0.12 10.9 0.0 2.2 2 0 0 2 2 2 2 Adaptin N terminal region HEAT_EZ PF13513.6 EWM24228.1 - 0.0017 18.8 9.3 3.6 8.2 0.0 5.9 5 1 1 6 6 6 1 HEAT-like repeat Trypan_PARP PF05887.11 EWM24229.1 - 9.2e-17 61.3 144.1 2.2e-11 43.9 63.9 2.1 1 1 1 2 2 2 2 Procyclic acidic repetitive protein (PARP) Mannosyl_trans PF05007.13 EWM24230.1 - 5e-73 246.2 4.4 7.3e-73 245.6 4.4 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 EWM24230.1 - 2.8e-15 56.3 8.4 5e-15 55.4 8.4 1.6 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U GT87 PF09594.10 EWM24230.1 - 0.00099 18.9 39.5 0.17 11.6 34.9 3.5 2 1 0 2 2 2 1 Glycosyltransferase family 87 CoA_binding_3 PF13727.6 EWM24230.1 - 4.5 7.2 6.8 2.6 8.0 1.2 2.4 2 0 0 2 2 2 0 CoA-binding domain 5_3_exonuc_N PF02739.16 EWM24231.1 - 2.9e-43 147.5 0.0 4.3e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 EWM24231.1 - 7.3e-21 74.6 0.0 1.6e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold DNA_pol_A PF00476.20 EWM24231.1 - 4e-10 39.3 0.0 6.3e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A HHH_5 PF14520.6 EWM24231.1 - 0.00086 19.9 0.0 0.0022 18.5 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 EWM24231.1 - 0.00097 19.2 0.0 0.003 17.6 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.23 EWM24231.1 - 0.0027 17.5 0.2 0.049 13.5 0.1 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix motif GAF_2 PF13185.6 EWM24232.1 - 1.1e-05 25.7 0.0 0.00011 22.5 0.0 2.5 2 0 0 2 2 2 1 GAF domain Tim44 PF04280.15 EWM24233.1 - 2.7e-28 98.9 0.0 6e-28 97.8 0.0 1.6 1 0 0 1 1 1 1 Tim44-like domain TpcC PF12642.7 EWM24233.1 - 0.0035 17.2 0.0 0.0079 16.0 0.0 1.6 1 0 0 1 1 1 1 Conjugative transposon protein TcpC DUF2884 PF11101.8 EWM24233.1 - 0.0092 15.5 5.6 0.091 12.3 2.3 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2884) T2SSF PF00482.23 EWM24233.1 - 0.031 14.2 0.3 0.14 12.1 0.3 2.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F ApoLp-III PF07464.11 EWM24233.1 - 0.17 11.9 11.0 0.12 12.4 2.3 2.9 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) GLE1 PF07817.13 EWM24233.1 - 0.39 9.9 3.1 0.65 9.2 3.1 1.3 1 0 0 1 1 1 0 GLE1-like protein COMPASS-Shg1 PF05205.12 EWM24233.1 - 3.9 8.2 6.9 49 4.7 6.9 2.5 1 1 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 PPR_2 PF13041.6 EWM24234.1 - 1.4e-50 169.3 0.1 3.2e-08 33.7 0.0 10.8 2 1 10 12 12 12 10 PPR repeat family PPR_3 PF13812.6 EWM24234.1 - 4.1e-49 164.5 0.0 1e-09 38.3 0.0 6.9 5 1 2 7 7 7 7 Pentatricopeptide repeat domain PPR PF01535.20 EWM24234.1 - 1.3e-43 144.2 12.7 0.00027 21.0 0.1 12.0 12 0 0 12 12 12 9 PPR repeat PPR_1 PF12854.7 EWM24234.1 - 1e-33 114.7 0.0 7.9e-07 28.7 0.0 9.1 9 0 0 9 9 9 6 PPR repeat PPR_long PF17177.4 EWM24234.1 - 1.8e-22 79.8 5.4 2.2e-10 40.3 0.0 4.5 2 1 3 5 5 5 4 Pentacotripeptide-repeat region of PRORP PDZ_2 PF13180.6 EWM24234.1 - 3.7e-05 24.0 0.0 0.096 13.0 0.0 2.5 2 0 0 2 2 2 2 PDZ domain TPR_10 PF13374.6 EWM24234.1 - 5.3e-05 22.9 0.0 0.00036 20.3 0.0 2.6 2 0 0 2 2 1 1 Tetratricopeptide repeat PDZ_6 PF17820.1 EWM24234.1 - 7.4e-05 22.5 0.1 0.00023 20.9 0.1 1.9 1 0 0 1 1 1 1 PDZ domain MRP-S27 PF10037.9 EWM24234.1 - 0.0005 19.0 0.0 0.82 8.5 0.0 3.3 2 1 0 3 3 3 2 Mitochondrial 28S ribosomal protein S27 PDZ PF00595.24 EWM24234.1 - 0.0013 19.0 0.0 0.024 15.0 0.1 2.4 2 0 0 2 2 2 1 PDZ domain TPR_12 PF13424.6 EWM24234.1 - 0.0092 16.2 1.0 1.8 8.9 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat ECSIT PF06239.11 EWM24234.1 - 0.017 14.3 2.1 7.8 5.6 0.0 5.4 6 2 2 8 8 8 0 Evolutionarily conserved signalling intermediate in Toll pathway TPR_7 PF13176.6 EWM24234.1 - 0.062 13.3 0.0 28 5.1 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat ATP13 PF12921.7 EWM24234.1 - 0.14 12.1 0.0 27 4.7 0.0 3.6 3 1 0 3 3 3 0 Mitochondrial ATPase expression TPR_2 PF07719.17 EWM24234.1 - 0.19 11.9 0.7 2.9 8.2 0.2 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EWM24234.1 - 0.44 10.4 1.2 2.2 8.2 0.2 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 EWM24234.1 - 1 10.2 4.5 5.3 8.0 0.0 4.6 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EWM24234.1 - 5.3 7.9 7.1 12 6.7 0.0 4.8 6 0 0 6 6 5 0 Tetratricopeptide repeat cobW PF02492.19 EWM24235.1 - 6.7e-34 117.0 0.0 9.1e-34 116.6 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EWM24235.1 - 0.00051 19.1 0.2 0.14 11.1 0.2 2.1 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB T2SSE PF00437.20 EWM24235.1 - 0.014 14.5 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein MMR_HSR1 PF01926.23 EWM24235.1 - 0.029 14.4 0.0 0.08 13.0 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 EWM24235.1 - 0.065 13.7 0.6 0.59 10.6 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 EWM24235.1 - 0.094 13.1 0.0 0.13 12.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 EWM24235.1 - 0.21 12.1 0.0 0.36 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EWM24236.1 - 5.7e-34 117.2 0.0 7.6e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EWM24236.1 - 0.00041 19.4 0.2 0.12 11.3 0.2 2.1 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB T2SSE PF00437.20 EWM24236.1 - 0.013 14.6 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein MMR_HSR1 PF01926.23 EWM24236.1 - 0.025 14.7 0.0 0.067 13.3 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 EWM24236.1 - 0.083 13.3 0.0 0.12 12.7 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EWM24236.1 - 0.11 13.0 0.1 0.54 10.8 0.0 1.9 2 0 0 2 2 2 0 ABC transporter KAP_NTPase PF07693.14 EWM24236.1 - 0.2 10.9 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_23 PF13476.6 EWM24236.1 - 0.21 12.1 0.0 0.33 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain FAD_binding_3 PF01494.19 EWM24238.1 - 6.7e-24 84.8 0.1 3e-23 82.6 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EWM24238.1 - 2.2e-06 27.0 0.0 3.2e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 EWM24238.1 - 0.00011 21.9 0.0 0.00018 21.2 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EWM24238.1 - 0.00027 20.1 0.3 0.00079 18.6 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EWM24238.1 - 0.00034 20.8 0.3 0.001 19.2 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EWM24238.1 - 0.00085 18.6 0.0 0.0025 17.1 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EWM24238.1 - 0.022 15.3 0.0 0.051 14.1 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EWM24238.1 - 0.031 13.5 0.1 0.05 12.8 0.1 1.2 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 EWM24238.1 - 0.13 11.6 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase SPRY PF00622.28 EWM24239.1 - 1.7e-11 44.3 0.1 2.1e-05 24.6 0.3 2.7 2 1 0 2 2 2 2 SPRY domain DUF1995 PF09353.10 EWM24240.1 - 1.9e-09 37.8 0.0 4.1e-09 36.8 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1995) RecG_wedge PF17191.4 EWM24241.1 - 7.9e-12 45.1 0.0 1.1e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 RecG wedge domain HHH_5 PF14520.6 EWM24241.1 - 0.037 14.6 0.0 0.08 13.6 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 EWM24241.1 - 0.068 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda Cdd1 PF11731.8 EWM24241.1 - 0.081 13.2 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Pathogenicity locus Transcrip_reg PF01709.20 EWM24242.1 - 2.6e-62 210.4 3.1 3.3e-62 210.1 3.1 1.0 1 0 0 1 1 1 1 Transcriptional regulator Rad21_Rec8_N PF04825.13 EWM24243.1 - 1.5e-39 134.6 0.0 1.7e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein CNDH2_N PF06278.11 EWM24243.1 - 0.026 14.7 0.0 0.028 14.6 0.0 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal WD40 PF00400.32 EWM24244.1 - 5e-52 172.7 13.0 1.4e-06 28.9 0.1 8.6 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM24244.1 - 2.1e-10 40.7 0.0 0.0046 17.2 0.0 5.6 2 2 4 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EWM24244.1 - 1.4e-05 24.1 0.0 0.15 10.7 0.0 3.0 2 1 1 3 3 3 2 Nup133 N terminal like Nup160 PF11715.8 EWM24244.1 - 7.2e-05 21.6 0.5 1.6 7.3 0.0 3.9 2 2 2 4 4 4 3 Nucleoporin Nup120/160 Frtz PF11768.8 EWM24244.1 - 0.00034 19.1 0.0 0.00068 18.1 0.0 1.4 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 EWM24244.1 - 0.00064 18.8 1.5 0.026 13.5 0.0 3.4 2 2 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 EWM24244.1 - 0.0026 17.4 1.4 0.33 10.5 0.0 2.7 2 1 0 3 3 3 1 PQQ-like domain PALB2_WD40 PF16756.5 EWM24244.1 - 0.07 12.0 0.8 1.4 7.8 0.0 2.5 2 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Cons_hypoth95 PF03602.15 EWM24245.1 - 3.8e-38 131.0 0.0 4.9e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 EWM24245.1 - 0.0013 19.4 0.0 0.0026 18.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EWM24245.1 - 0.0026 17.3 0.0 0.0039 16.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain MethyltransfD12 PF02086.15 EWM24245.1 - 0.054 13.2 0.0 0.08 12.6 0.0 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Methyltrans_SAM PF10672.9 EWM24245.1 - 0.097 11.8 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase TFIIE_alpha PF02002.17 EWM24246.1 - 5.7e-17 61.5 2.0 9.3e-17 60.8 2.0 1.3 1 0 0 1 1 1 1 TFIIE alpha subunit RNase_H_2 PF13482.6 EWM24246.1 - 0.00054 20.0 0.0 0.0015 18.5 0.0 1.7 1 1 0 1 1 1 1 RNase_H superfamily Arc_trans_TRASH PF08394.10 EWM24246.1 - 0.022 15.1 1.3 0.057 13.8 1.3 1.6 1 0 0 1 1 1 0 Archaeal TRASH domain DUF4192 PF13830.6 EWM24246.1 - 0.036 14.1 1.2 0.078 13.0 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Methyltransf_10 PF05971.12 EWM24247.1 - 4.9e-76 255.9 0.0 8.1e-44 150.1 0.0 2.1 2 0 0 2 2 2 2 RNA methyltransferase PrmA PF06325.13 EWM24247.1 - 1.5e-06 27.8 0.0 2.4e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EWM24247.1 - 4.3e-05 23.1 0.0 0.18 11.4 0.0 2.9 1 1 1 2 2 2 2 Methyltransferase small domain Methyltransf_12 PF08242.12 EWM24247.1 - 0.0035 18.1 0.0 0.0082 16.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM24247.1 - 0.022 15.5 0.0 0.058 14.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EWM24247.1 - 0.035 13.9 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.18 EWM24247.1 - 0.038 13.7 0.0 5.5 6.6 0.0 2.3 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.12 EWM24247.1 - 0.16 12.6 0.0 0.39 11.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 EWM24247.1 - 0.19 11.7 0.0 0.36 10.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain RhoGEF PF00621.20 EWM24248.1 - 2.6e-44 151.6 0.0 3.9e-44 151.0 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PDZ_6 PF17820.1 EWM24248.1 - 6.5e-09 35.5 0.0 1.8e-08 34.1 0.0 1.7 2 0 0 2 2 2 1 PDZ domain PH PF00169.29 EWM24248.1 - 2e-06 28.3 0.0 3.7e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 PH domain PDZ_2 PF13180.6 EWM24248.1 - 2.2e-05 24.7 0.0 6e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EWM24248.1 - 0.059 13.7 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Tricorn_PDZ PF14685.6 EWM24248.1 - 0.07 13.1 0.1 0.22 11.5 0.0 1.9 2 0 0 2 2 2 0 Tricorn protease PDZ domain Med22 PF06179.12 EWM24249.1 - 1.1e-06 28.9 2.4 1.4e-06 28.5 2.4 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex BORCS7 PF16088.5 EWM24249.1 - 0.0037 17.5 0.3 0.0044 17.2 0.3 1.3 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 7 CENP-R PF06729.12 EWM24249.1 - 0.018 15.0 0.5 0.022 14.7 0.5 1.2 1 0 0 1 1 1 0 Kinetochore component, CENP-R APC_N_CC PF16689.5 EWM24249.1 - 0.12 12.4 1.2 1.4 9.1 1.2 2.2 1 1 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain SUZ PF12752.7 EWM24250.1 - 3.1e-10 40.7 2.4 3.1e-10 40.7 2.4 2.6 1 1 1 2 2 2 1 SUZ domain R3H PF01424.22 EWM24250.1 - 5.8e-07 29.4 0.0 9.2e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 R3H domain Ribosomal_L22 PF00237.19 EWM24251.1 - 7.8e-40 135.3 0.0 1e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e SATase_N PF06426.14 EWM24252.1 - 4.9e-18 65.4 0.1 7.4e-18 64.9 0.1 1.3 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep PF00132.24 EWM24252.1 - 1.7e-09 37.0 6.8 6.8e-06 25.6 1.3 2.4 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) T6SS_TssG PF06996.11 EWM24252.1 - 0.076 12.3 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Type VI secretion, TssG Hexapep_2 PF14602.6 EWM24252.1 - 0.093 12.5 14.2 0.074 12.8 5.7 2.8 2 1 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Peptidase_C97 PF05903.14 EWM24253.1 - 0.029 14.2 0.1 0.054 13.3 0.1 1.4 1 0 0 1 1 1 0 PPPDE putative peptidase domain zf-HC5HC2H_2 PF13832.6 EWM24254.1 - 3e-52 175.4 44.8 6.9e-23 80.9 2.8 7.0 8 0 0 8 8 8 4 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EWM24254.1 - 2.9e-27 94.8 21.3 5.8e-15 55.3 1.6 8.1 7 2 3 10 10 10 4 PHD-like zinc-binding domain PHD PF00628.29 EWM24254.1 - 3.7e-22 78.0 83.9 3.5e-09 36.4 4.4 8.4 9 0 0 9 9 9 6 PHD-finger PHD_2 PF13831.6 EWM24254.1 - 2.2e-21 75.1 45.4 7.1e-11 41.5 4.7 6.6 6 0 0 6 6 6 3 PHD-finger Bromodomain PF00439.25 EWM24254.1 - 4.6e-17 61.9 0.0 9.1e-17 60.9 0.0 1.4 1 0 0 1 1 1 1 Bromodomain NAD_binding_10 PF13460.6 EWM24255.1 - 6.5e-37 127.2 0.1 7.9e-37 126.9 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EWM24255.1 - 9.9e-11 41.6 0.1 1.5e-10 41.1 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 EWM24255.1 - 1.8e-07 30.5 0.0 2.2e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EWM24255.1 - 1.5e-06 27.8 0.0 2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EWM24255.1 - 0.0018 17.8 0.1 0.003 17.0 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 EWM24255.1 - 0.0028 16.8 0.2 0.41 9.8 0.1 2.3 2 0 0 2 2 2 2 Male sterility protein NAD_binding_7 PF13241.6 EWM24255.1 - 0.011 16.2 0.3 1 9.9 0.3 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding DapB_N PF01113.20 EWM24255.1 - 0.017 15.2 2.1 0.038 14.1 0.9 2.1 2 1 1 3 3 3 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 EWM24255.1 - 0.019 15.4 0.1 0.046 14.1 0.1 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EWM24255.1 - 0.022 14.8 0.2 0.048 13.7 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase KR PF08659.10 EWM24255.1 - 0.16 11.9 0.9 1.1 9.1 0.9 2.0 1 1 0 1 1 1 0 KR domain DHquinase_I PF01487.15 EWM24256.1 - 1.8e-37 129.8 0.0 2.6e-37 129.3 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 EWM24256.1 - 2.4e-23 82.2 0.0 9.1e-23 80.3 0.0 2.0 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 EWM24256.1 - 2.9e-12 46.1 1.6 6.5e-12 45.0 1.6 1.7 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 EWM24256.1 - 0.0011 19.0 0.0 0.0029 17.7 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 EWM24256.1 - 0.0067 15.8 0.1 0.021 14.1 0.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 EWM24256.1 - 0.039 14.2 0.4 1.3 9.3 0.2 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Rad51 PF08423.11 EWM24257.1 - 5.6e-47 160.2 0.3 8.1e-47 159.6 0.3 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 EWM24257.1 - 1.5e-05 24.7 0.1 2.1e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 EWM24257.1 - 2.1e-05 24.0 0.1 3.3e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 KaiC HHH_5 PF14520.6 EWM24257.1 - 0.00011 22.8 2.2 0.00015 22.3 0.7 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain AAA_25 PF13481.6 EWM24257.1 - 0.014 15.0 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain HhH-GPD PF00730.25 EWM24257.1 - 0.097 13.1 0.0 0.71 10.4 0.0 2.0 1 1 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein HEPN_RiboL-PSP PF18735.1 EWM24257.1 - 0.15 12.0 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 RiboL-PSP-HEPN MFS_1 PF07690.16 EWM24258.1 - 6.4e-26 91.1 20.0 5.5e-25 88.0 18.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EWM24258.1 - 8.4e-07 28.2 5.5 0.00042 19.3 5.5 2.6 1 1 0 1 1 1 1 MFS_1 like family Sugar_tr PF00083.24 EWM24258.1 - 0.00016 20.7 5.0 0.00016 20.7 5.0 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter Nuc_H_symport PF03825.16 EWM24258.1 - 0.099 11.6 4.6 0.18 10.8 4.6 1.3 1 0 0 1 1 1 0 Nucleoside H+ symporter MFS_4 PF06779.14 EWM24258.1 - 0.22 10.8 10.6 0.066 12.5 3.1 2.5 2 1 1 3 3 3 0 Uncharacterised MFS-type transporter YbfB ELO PF01151.18 EWM24259.1 - 1e-40 139.9 15.8 1.4e-40 139.4 15.8 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family MG4 PF17789.1 EWM24259.1 - 0.11 12.6 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Macroglobulin domain MG4 VPS9 PF02204.18 EWM24260.1 - 1.9e-10 40.9 0.0 3.4e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain C1_1 PF00130.22 EWM24260.1 - 4.3e-07 29.7 3.9 9.1e-07 28.7 3.9 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE PF01363.21 EWM24260.1 - 1.3 9.2 6.2 2.7 8.2 5.3 2.1 1 1 0 1 1 1 0 FYVE zinc finger DUF4460 PF14687.6 EWM24261.1 - 4.9e-10 39.4 2.5 7.5e-10 38.8 0.1 2.5 3 1 0 3 3 3 1 Domain of unknown function (DUF4460) Cohesin_load PF10345.9 EWM24261.1 - 0.011 14.2 2.1 0.022 13.2 0.3 1.9 2 0 0 2 2 2 0 Cohesin loading factor PseudoU_synth_2 PF00849.22 EWM24262.1 - 6.1e-25 88.2 0.0 8.6e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase PPR_2 PF13041.6 EWM24264.1 - 1.1e-21 76.7 0.0 2.4e-06 27.6 0.0 6.7 6 1 1 7 7 7 6 PPR repeat family PPR PF01535.20 EWM24264.1 - 1.2e-13 50.3 0.5 0.0061 16.7 0.0 5.7 5 0 0 5 5 5 3 PPR repeat PPR_3 PF13812.6 EWM24264.1 - 9e-12 44.9 0.0 0.0072 16.4 0.0 5.4 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 EWM24264.1 - 2.8e-11 42.9 0.0 0.017 14.8 0.0 5.7 5 0 0 5 5 5 2 PPR repeat PPR_long PF17177.4 EWM24264.1 - 0.0028 17.1 0.0 1.5 8.2 0.0 3.8 5 0 0 5 5 5 1 Pentacotripeptide-repeat region of PRORP TPR_16 PF13432.6 EWM24264.1 - 2.2 9.0 15.3 0.48 11.1 2.4 3.9 3 2 2 5 5 5 0 Tetratricopeptide repeat PqiA PF04403.13 EWM24265.1 - 1.6e-11 44.2 16.0 1.5e-07 31.4 4.0 3.0 2 1 0 2 2 2 2 Paraquat-inducible protein A 2OG-FeII_Oxy_3 PF13640.6 EWM24266.1 - 1.7e-16 60.9 0.0 3.1e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Nop52 PF05997.12 EWM24267.1 - 2.7e-56 190.8 0.0 3.7e-56 190.3 0.0 1.2 1 0 0 1 1 1 1 Nucleolar protein,Nop52 G-patch PF01585.23 EWM24268.1 - 1.5e-14 53.6 1.1 3.4e-14 52.4 1.1 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EWM24268.1 - 3.3e-06 27.1 0.3 7.7e-06 25.9 0.3 1.6 1 0 0 1 1 1 1 G-patch domain CPBP PF02517.16 EWM24269.1 - 6.9e-15 55.2 2.7 6.9e-15 55.2 2.7 2.0 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease Sec1 PF00995.23 EWM24270.1 - 3.8e-107 359.9 0.0 4.4e-107 359.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family OTCace_N PF02729.21 EWM24271.1 - 4e-42 143.7 0.0 4.1e-41 140.4 0.0 2.3 3 0 0 3 3 3 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 EWM24271.1 - 5.3e-33 114.3 0.0 8.2e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain LRR_6 PF13516.6 EWM24272.1 - 3.9e-15 54.5 28.9 0.017 15.1 0.1 12.3 14 0 0 14 14 14 7 Leucine Rich repeat LRR_4 PF12799.7 EWM24272.1 - 3.3e-11 43.2 3.0 0.02 15.3 0.1 7.0 6 1 0 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EWM24272.1 - 0.00016 21.4 15.7 0.55 10.0 0.6 8.9 7 4 0 7 7 7 1 Leucine rich repeat LRR_1 PF00560.33 EWM24272.1 - 0.012 16.1 10.0 1.3e+02 3.7 0.0 7.9 9 1 0 9 9 9 0 Leucine Rich Repeat FAM209 PF15206.6 EWM24273.1 - 0.065 13.0 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 FAM209 family SHS2_Rpb7-N PF03876.17 EWM24275.1 - 4.8e-10 39.7 0.1 1.5e-09 38.1 0.0 1.8 3 0 0 3 3 3 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 EWM24275.1 - 1.4e-08 35.0 0.0 3.5e-08 33.7 0.0 1.6 2 0 0 2 2 2 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 EWM24275.1 - 7.7e-06 26.2 0.0 1.7e-05 25.1 0.0 1.5 1 1 1 2 2 2 1 RNA polymerase III subunit Rpc25 S1 PF00575.23 EWM24276.1 - 9.7e-09 35.5 0.1 2.1e-08 34.4 0.0 1.5 2 0 0 2 2 2 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 EWM24276.1 - 4.6e-06 26.9 0.0 9.7e-06 25.8 0.0 1.5 1 1 1 2 2 2 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 EWM24276.1 - 0.00015 22.0 0.3 0.00048 20.4 0.0 1.9 3 0 0 3 3 3 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 F-box-like PF12937.7 EWM24277.1 - 9.3e-08 31.9 0.5 1.5e-07 31.2 0.5 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EWM24277.1 - 7.6e-06 25.7 0.1 1.5e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.11 EWM24277.1 - 0.023 15.2 0.0 0.036 14.6 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box_4 PF15966.5 EWM24277.1 - 0.031 14.2 0.1 0.052 13.4 0.1 1.2 1 0 0 1 1 1 0 F-box Band_7 PF01145.25 EWM24278.1 - 1.1e-21 77.7 7.5 7.2e-21 75.0 7.5 2.0 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 EWM24278.1 - 0.0014 17.8 2.4 0.0018 17.4 2.4 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial Med2 PF11214.8 EWM24278.1 - 0.0055 16.8 1.3 0.01 16.0 1.3 1.4 1 0 0 1 1 1 1 Mediator complex subunit 2 PPR_2 PF13041.6 EWM24279.1 - 2.1e-43 146.3 6.0 2.6e-09 37.1 0.0 11.0 5 3 7 12 12 12 7 PPR repeat family PPR PF01535.20 EWM24279.1 - 2e-39 131.1 22.8 2.1e-06 27.6 0.0 11.6 13 0 0 13 13 11 7 PPR repeat PPR_3 PF13812.6 EWM24279.1 - 1.1e-33 115.1 0.0 1.5e-07 31.4 0.0 7.3 5 2 2 7 7 7 6 Pentatricopeptide repeat domain PPR_long PF17177.4 EWM24279.1 - 6.3e-29 100.9 0.6 3.4e-08 33.1 0.2 5.5 4 1 2 6 6 6 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EWM24279.1 - 8.1e-22 76.6 0.0 1.6e-05 24.5 0.0 6.9 8 0 0 8 8 8 4 PPR repeat TPR_19 PF14559.6 EWM24279.1 - 0.00023 21.6 1.6 4.8 7.8 0.2 4.5 3 1 2 5 5 5 2 Tetratricopeptide repeat Smr PF01713.21 EWM24279.1 - 0.0015 18.9 0.0 0.0091 16.3 0.0 2.5 1 1 0 1 1 1 1 Smr domain TPR_15 PF13429.6 EWM24279.1 - 0.0019 17.5 5.3 1.4 8.1 0.2 3.7 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EWM24279.1 - 0.002 18.0 5.3 2.2 8.5 0.1 5.5 6 0 0 6 6 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EWM24279.1 - 0.0026 18.0 0.7 29 5.0 0.0 4.0 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 COX5A PF02284.16 EWM24279.1 - 0.0036 17.3 3.0 0.67 10.0 0.0 4.6 5 1 1 6 6 5 1 Cytochrome c oxidase subunit Va Clathrin PF00637.20 EWM24279.1 - 0.014 15.3 0.0 47 3.8 0.0 4.2 3 1 1 4 4 4 0 Region in Clathrin and VPS TPR_16 PF13432.6 EWM24279.1 - 0.026 15.2 9.7 3.6 8.3 0.0 5.8 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 EWM24279.1 - 0.1 12.8 8.9 18 5.7 0.1 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat BTAD PF03704.17 EWM24279.1 - 0.11 13.0 0.2 0.11 13.0 0.2 5.2 6 1 0 6 6 6 0 Bacterial transcriptional activator domain TPR_14 PF13428.6 EWM24279.1 - 2 9.5 26.6 9.7 7.3 0.1 9.9 10 2 2 12 12 11 0 Tetratricopeptide repeat TPR_4 PF07721.14 EWM24279.1 - 3.1 8.7 15.4 38 5.3 0.1 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Voltage_CLC PF00654.20 EWM24280.1 - 2.3e-78 263.9 18.7 2.3e-78 263.9 18.7 1.6 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EWM24280.1 - 2.8e-06 27.7 0.0 0.0053 17.2 0.0 2.6 2 0 0 2 2 2 2 CBS domain UCR_Fe-S_N PF10399.9 EWM24280.1 - 0.066 12.6 0.6 0.2 11.0 0.6 1.9 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal TAT_signal PF10518.9 EWM24280.1 - 6.2 6.8 9.5 1 9.3 2.5 3.2 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence CBS PF00571.28 EWM24281.1 - 3.3e-25 88.3 13.7 9.6e-07 29.2 0.8 5.1 5 0 0 5 5 5 4 CBS domain PB1 PF00564.24 EWM24281.1 - 0.00055 19.8 0.0 0.0018 18.1 0.0 1.9 1 0 0 1 1 1 1 PB1 domain TatD_DNase PF01026.21 EWM24282.1 - 1.3e-59 201.7 0.0 1.6e-59 201.3 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase AI-2E_transport PF01594.16 EWM24283.1 - 0.064 12.4 0.5 0.068 12.3 0.5 1.0 1 0 0 1 1 1 0 AI-2E family transporter Ribosomal_L35p PF01632.19 EWM24284.1 - 1.1e-14 54.7 3.2 1.7e-14 54.0 3.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L35 CLTH PF10607.9 EWM24287.1 - 4.7e-21 75.2 0.0 8.3e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 EWM24287.1 - 7.6e-07 29.1 1.4 1.5e-06 28.1 1.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EWM24287.1 - 8.5e-05 22.4 1.0 0.00018 21.4 1.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EWM24287.1 - 0.0046 17.3 0.9 0.011 16.0 0.9 1.7 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 EWM24287.1 - 0.0056 16.8 0.6 0.014 15.5 0.6 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DUF1841 PF08897.11 EWM24287.1 - 0.086 12.9 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1841) zf-C3HC4 PF00097.25 EWM24287.1 - 0.16 11.8 0.8 0.38 10.6 0.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EWM24287.1 - 0.21 11.4 1.1 0.5 10.3 0.1 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EWM24287.1 - 0.39 10.6 1.9 0.98 9.3 1.9 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DNA_topoisoIV PF00521.20 EWM24288.1 - 1.7e-144 481.9 0.0 2.1e-144 481.6 0.0 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 EWM24288.1 - 3.8e-57 189.6 4.5 1e-11 44.1 0.0 6.5 6 0 0 6 6 6 6 DNA gyrase C-terminal domain, beta-propeller DUF4890 PF16231.5 EWM24288.1 - 0.12 12.9 1.9 0.26 11.8 1.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4890) Thioredoxin PF00085.20 EWM24289.1 - 5.2e-26 90.6 0.0 7.5e-26 90.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EWM24289.1 - 0.00058 19.3 0.1 0.0015 17.9 0.1 1.7 1 1 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 EWM24289.1 - 0.0041 16.9 0.0 0.0059 16.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EWM24289.1 - 0.011 16.2 0.0 0.06 13.8 0.0 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_3 PF13192.6 EWM24289.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain DUF4745 PF15923.5 EWM24289.1 - 0.23 11.4 0.9 0.41 10.6 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4745) Helicase_C PF00271.31 EWM24290.1 - 7.4e-16 58.5 0.0 5.1e-14 52.6 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RNase_T PF00929.24 EWM24290.1 - 4.3e-11 43.6 0.0 2.8e-10 41.0 0.0 2.2 1 1 0 1 1 1 1 Exonuclease DEAD PF00270.29 EWM24290.1 - 7.6e-07 29.1 0.0 0.0002 21.2 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase Antimicrobial12 PF08107.11 EWM24291.1 - 8.5e-05 22.2 0.1 0.00021 21.0 0.0 1.6 2 0 0 2 2 2 1 Pleurocidin family Capsid_VP7 PF17071.5 EWM24291.1 - 0.12 11.6 0.2 0.2 10.9 0.2 1.3 1 0 0 1 1 1 0 Outer capsid protein VP7 EXS PF03124.14 EWM24292.1 - 1e-75 255.1 18.1 1.4e-75 254.7 18.1 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 EWM24292.1 - 5.3e-24 85.9 2.6 8.5e-12 45.7 0.4 2.3 1 1 1 2 2 2 2 SPX domain FliD_C PF07195.12 EWM24292.1 - 0.041 13.3 0.1 0.06 12.8 0.1 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus MMR_HSR1_C PF08438.10 EWM24293.1 - 2.5e-30 105.3 0.0 4.7e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 EWM24293.1 - 3.7e-19 68.9 0.0 9.1e-19 67.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EWM24293.1 - 3.4e-08 33.2 0.6 2.1e-07 30.6 0.2 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B TGS PF02824.21 EWM24293.1 - 0.15 12.1 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 TGS domain Ribosomal_S25 PF03297.15 EWM24294.1 - 1.7e-41 140.5 4.8 1.9e-41 140.3 4.8 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.6 EWM24294.1 - 0.0011 18.4 0.3 0.0016 17.9 0.3 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 EWM24294.1 - 0.0018 18.1 0.1 0.0024 17.7 0.1 1.2 1 0 0 1 1 1 1 MarR family Fe_dep_repress PF01325.19 EWM24294.1 - 0.012 15.8 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain GntR PF00392.21 EWM24294.1 - 0.025 14.2 0.3 0.075 12.7 0.1 1.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family SatD PF16264.5 EWM24294.1 - 0.054 13.1 0.2 0.068 12.8 0.2 1.1 1 0 0 1 1 1 0 SatD family (SatD) Rrf2 PF02082.20 EWM24294.1 - 0.08 13.3 0.1 0.13 12.6 0.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator PaaX PF07848.12 EWM24294.1 - 0.092 13.0 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 PaaX-like protein MarR PF01047.22 EWM24294.1 - 0.24 11.4 1.2 0.25 11.3 0.1 1.5 2 0 0 2 2 2 0 MarR family tRNA-synt_2 PF00152.20 EWM24295.1 - 2.4e-77 260.1 0.0 3e-77 259.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) GST_C PF00043.25 EWM24295.1 - 2.2e-09 37.4 0.0 4.8e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA_anti-codon PF01336.25 EWM24295.1 - 9.8e-09 35.1 0.0 1.9e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain GST_C_2 PF13410.6 EWM24295.1 - 6.5e-06 26.1 0.0 2e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EWM24295.1 - 0.00064 19.9 0.0 0.0016 18.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_2d PF01409.20 EWM24295.1 - 0.026 14.0 0.1 0.19 11.2 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) PIP49_N PF14875.6 EWM24297.1 - 0.11 12.3 1.1 0.13 12.1 1.1 1.1 1 0 0 1 1 1 0 N-term cysteine-rich ER, FAM69 DUF1189 PF06691.11 EWM24297.1 - 0.23 11.0 4.6 0.26 10.8 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) Alg14 PF08660.11 EWM24298.1 - 9.1e-59 198.3 0.0 1.3e-58 197.8 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Atg14 PF10186.9 EWM24299.1 - 8.3e-15 54.7 1.3 8.3e-07 28.4 3.0 2.1 2 0 0 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 ATG16 PF08614.11 EWM24299.1 - 0.024 14.9 5.7 0.038 14.2 5.7 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) ERM PF00769.19 EWM24299.1 - 0.033 14.0 4.7 0.044 13.6 4.7 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family SlyX PF04102.12 EWM24299.1 - 5.2 7.8 6.4 9.6 6.9 1.3 2.4 1 1 1 2 2 2 0 SlyX ATP-grasp_2 PF08442.10 EWM24300.1 - 7.8e-64 215.0 1.0 1.2e-63 214.3 0.3 1.7 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 EWM24300.1 - 1.3e-24 86.7 1.8 1.3e-24 86.7 1.8 2.0 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.6 EWM24300.1 - 4.1e-05 23.1 0.3 4.1e-05 23.1 0.3 1.7 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 EWM24300.1 - 5.2e-05 23.1 1.2 0.014 15.2 0.0 2.5 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Alba PF01918.21 EWM24300.1 - 0.013 15.3 0.3 0.028 14.2 0.3 1.6 1 0 0 1 1 1 0 Alba ATP-grasp_2 PF08442.10 EWM24301.1 - 1.4e-63 214.2 0.3 1.4e-63 214.2 0.3 1.9 3 0 0 3 3 3 1 ATP-grasp domain Ligase_CoA PF00549.19 EWM24301.1 - 1.4e-24 86.6 1.8 1.4e-24 86.6 1.8 2.0 2 0 0 2 2 2 1 CoA-ligase GARS_A PF01071.19 EWM24301.1 - 3e-05 23.9 3.0 0.015 15.1 0.0 2.5 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.6 EWM24301.1 - 4.5e-05 23.0 0.3 4.5e-05 23.0 0.3 2.1 2 0 0 2 2 2 1 ATP-grasp domain Alba PF01918.21 EWM24301.1 - 0.009 15.8 0.2 0.02 14.7 0.2 1.5 1 0 0 1 1 1 1 Alba Las1 PF04031.13 EWM24302.1 - 6.8e-45 152.9 0.3 1e-44 152.4 0.3 1.3 1 0 0 1 1 1 1 Las1-like Methyltransf_25 PF13649.6 EWM24303.1 - 3.9e-08 33.9 0.1 1.4e-07 32.2 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM24303.1 - 3.2e-07 30.2 0.0 4.7e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM24303.1 - 1.8e-06 28.5 0.1 5.2e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EWM24303.1 - 3.4e-06 27.0 0.0 4.2e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EWM24303.1 - 1.2e-05 24.8 0.0 1.7e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DOT1 PF08123.13 EWM24303.1 - 1.2e-05 24.9 0.0 1.8e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_12 PF08242.12 EWM24303.1 - 2.9e-05 24.7 0.0 0.00033 21.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 EWM24303.1 - 6.4e-05 22.5 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MetW PF07021.12 EWM24303.1 - 0.003 17.2 0.0 0.0044 16.6 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 EWM24303.1 - 0.0098 15.5 0.0 0.02 14.4 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EWM24303.1 - 0.01 15.8 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EWM24303.1 - 0.024 14.1 0.0 0.032 13.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 EWM24303.1 - 0.034 14.1 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 EWM24303.1 - 0.05 12.9 0.0 0.073 12.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain UPF0020 PF01170.18 EWM24303.1 - 0.098 12.3 0.1 0.36 10.5 0.1 1.8 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Sel1 PF08238.12 EWM24304.1 - 1.1e-30 105.3 30.2 2.8e-06 27.8 0.2 11.7 12 0 0 12 12 12 7 Sel1 repeat DUF4085 PF13315.6 EWM24304.1 - 0.25 11.0 0.1 0.44 10.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) Cullin PF00888.22 EWM24305.1 - 2.7e-215 716.6 4.3 3.3e-215 716.4 4.3 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EWM24305.1 - 1.9e-26 91.8 0.0 5.3e-26 90.4 0.0 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain AMP-binding PF00501.28 EWM24306.1 - 1.6e-80 270.8 0.0 3.1e-80 269.9 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 EWM24307.1 - 1.6e-80 270.8 0.0 3.1e-80 269.9 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme tRNA-synt_2 PF00152.20 EWM24309.1 - 4.3e-75 252.7 0.0 5.4e-75 252.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) WHEP-TRS PF00458.20 EWM24309.1 - 1.3e-15 57.3 0.5 2.5e-15 56.4 0.5 1.5 1 0 0 1 1 1 1 WHEP-TRS domain tRNA-synt_2d PF01409.20 EWM24309.1 - 0.008 15.7 0.2 0.71 9.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) OTU PF02338.19 EWM24311.1 - 2.7e-14 53.8 0.0 5.6e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EWM24311.1 - 0.00089 18.8 0.0 0.73 9.2 0.0 2.9 2 1 1 3 3 3 2 Peptidase C65 Otubain DnaJ_C PF01556.18 EWM24312.1 - 3.6e-35 121.2 0.0 8.2e-35 120.1 0.0 1.5 1 1 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EWM24312.1 - 2.4e-23 82.0 4.0 4e-23 81.3 4.0 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EWM24312.1 - 2e-12 47.3 19.3 4.4e-12 46.2 19.3 1.6 1 0 0 1 1 1 1 DnaJ central domain L_biotic_typeA PF04604.13 EWM24312.1 - 0.15 11.9 0.9 16 5.5 0.3 2.8 2 0 0 2 2 2 0 Type-A lantibiotic zinc-ribbons_6 PF07191.12 EWM24312.1 - 0.3 11.1 6.5 0.67 10.0 6.5 1.6 1 0 0 1 1 1 0 zinc-ribbons Anti-TRAP PF15777.5 EWM24312.1 - 1.4 8.9 17.7 5.9 6.9 4.7 3.2 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein DZR PF12773.7 EWM24312.1 - 2.9 8.0 13.5 1.3 9.1 9.3 2.5 2 1 0 2 2 2 0 Double zinc ribbon RseC_MucC PF04246.12 EWM24312.1 - 5.4 7.0 7.4 1.6 8.7 1.2 2.4 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC UQ_con PF00179.26 EWM24313.1 - 2.1e-35 121.4 0.0 3.2e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EWM24313.1 - 0.018 14.7 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B Slu7 PF11708.8 EWM24314.1 - 3.3e-87 292.6 20.0 3.3e-87 292.6 20.0 2.2 3 1 0 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 EWM24314.1 - 0.096 12.4 0.5 0.21 11.4 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 EWM24314.1 - 0.27 11.4 2.0 0.61 10.3 2.0 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF755 PF05501.11 EWM24314.1 - 0.82 10.0 4.7 2.5 8.4 4.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF4050 PF13259.6 EWM24314.1 - 3.1 8.1 10.8 0.36 11.1 5.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) Exo_endo_phos PF03372.23 EWM24315.1 - 2.1e-11 43.8 0.0 5e-11 42.6 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Fer2 PF00111.27 EWM24316.1 - 5.6e-08 32.6 2.2 1.1e-07 31.7 2.2 1.5 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain UAA PF08449.11 EWM24317.1 - 3.8e-43 147.8 12.7 5.3e-43 147.4 12.7 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EWM24317.1 - 2.7e-06 27.6 23.9 6.4e-06 26.4 9.4 3.0 2 1 1 3 3 3 2 EamA-like transporter family TPT PF03151.16 EWM24317.1 - 0.00014 21.3 12.1 0.011 15.1 2.3 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family CrgA PF06781.12 EWM24317.1 - 0.17 11.9 5.2 2.9 8.0 0.7 3.1 3 0 0 3 3 3 0 Cell division protein CrgA DUF1361 PF07099.11 EWM24317.1 - 4.1 7.4 6.1 0.26 11.2 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1361) Aa_trans PF01490.18 EWM24318.1 - 1.8e-57 194.9 15.8 2.2e-57 194.6 15.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aldo_ket_red PF00248.21 EWM24319.1 - 8.2e-54 182.8 0.0 1.2e-32 113.3 0.0 2.1 2 0 0 2 2 2 2 Aldo/keto reductase family Pkinase PF00069.25 EWM24320.1 - 4.2e-37 128.0 0.0 8.7e-37 126.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM24320.1 - 4.6e-16 58.9 0.0 7e-16 58.3 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EWM24320.1 - 5.8e-07 29.7 2.2 7.8e-05 22.7 0.2 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EWM24320.1 - 0.0002 20.8 0.0 0.42 9.9 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EWM24320.1 - 0.011 14.6 0.0 0.017 13.9 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Pribosyltran PF00156.27 EWM24321.1 - 8.5e-20 70.9 0.0 1.3e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain KH_8 PF17903.1 EWM24322.1 - 2.5e-31 107.6 0.4 6.1e-31 106.3 0.1 1.9 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 EWM24322.1 - 0.052 13.4 0.3 0.24 11.3 0.0 2.2 3 0 0 3 3 3 0 KH domain dCMP_cyt_deam_2 PF08211.12 EWM24322.1 - 0.057 13.6 0.2 0.18 12.0 0.0 1.8 2 0 0 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region NAD_binding_10 PF13460.6 EWM24323.1 - 2.5e-06 27.5 0.1 5.9e-06 26.3 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding YtxH PF12732.7 EWM24324.1 - 0.0055 17.2 3.9 2.2 8.9 3.9 2.5 1 1 0 1 1 1 1 YtxH-like protein Apolipoprotein PF01442.18 EWM24324.1 - 0.011 15.7 0.0 0.017 15.0 0.0 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 EWM24324.1 - 0.019 15.1 0.1 0.035 14.2 0.1 1.6 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF883 PF05957.13 EWM24324.1 - 0.021 15.4 0.6 0.55 10.9 0.1 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) ApoC-I PF04691.12 EWM24324.1 - 0.032 14.2 0.2 2.4 8.1 0.0 2.5 1 1 1 2 2 2 0 Apolipoprotein C-I (ApoC-1) Ank_2 PF12796.7 EWM24325.1 - 0.0029 18.2 0.0 0.0072 16.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EWM24325.1 - 0.098 13.0 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Rpn3_C PF08375.11 EWM24327.1 - 1.3e-21 76.8 0.1 2.7e-21 75.7 0.1 1.6 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 EWM24327.1 - 2.1e-20 73.2 0.0 5.5e-20 71.8 0.0 1.8 1 0 0 1 1 1 1 PCI domain Mito_fiss_reg PF05308.11 EWM24327.1 - 0.095 12.8 1.9 0.15 12.1 1.9 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator F-box-like PF12937.7 EWM24328.1 - 1.6e-06 27.9 0.4 4e-06 26.6 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EWM24328.1 - 0.0021 17.9 0.0 0.0048 16.7 0.0 1.6 1 0 0 1 1 1 1 F-box domain zf-RanBP PF00641.18 EWM24328.1 - 0.0038 16.5 1.8 0.0038 16.5 1.8 2.9 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DZR PF12773.7 EWM24328.1 - 5.2 7.2 9.6 0.95 9.5 2.4 2.5 2 0 0 2 2 2 0 Double zinc ribbon Cytochrom_B561 PF03188.16 EWM24329.1 - 1.3e-13 51.3 9.3 1.8e-13 50.8 9.3 1.2 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF420 PF04238.12 EWM24329.1 - 0.016 15.5 7.9 0.041 14.2 7.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF420) DUF4079 PF13301.6 EWM24329.1 - 0.089 12.9 10.1 0.32 11.1 9.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) Polysacc_synt_C PF14667.6 EWM24329.1 - 0.12 12.4 5.7 7.8 6.5 4.1 2.1 1 1 1 2 2 2 0 Polysaccharide biosynthesis C-terminal domain DUF5134 PF17197.4 EWM24329.1 - 0.13 12.2 4.2 0.17 11.8 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5134) DUF4293 PF14126.6 EWM24329.1 - 0.13 12.5 7.5 0.19 12.0 5.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) DUF5373 PF17343.2 EWM24329.1 - 0.22 11.3 4.2 0.092 12.6 1.9 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5373) SUR7 PF06687.12 EWM24329.1 - 0.47 10.0 5.9 0.76 9.4 5.9 1.4 1 0 0 1 1 1 0 SUR7/PalI family PRA1 PF03208.19 EWM24329.1 - 0.94 9.1 8.1 0.34 10.5 4.7 1.8 2 0 0 2 2 2 0 PRA1 family protein PAP2 PF01569.21 EWM24329.1 - 3.6 7.4 10.0 0.21 11.4 1.8 2.5 1 1 1 2 2 2 0 PAP2 superfamily SAC3_GANP PF03399.16 EWM24330.1 - 7.8e-44 150.2 0.0 1.1e-43 149.7 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 EWM24330.1 - 1.5e-07 31.5 0.0 2.4e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family NUDIX PF00293.28 EWM24331.1 - 1e-12 48.2 0.0 3.8e-12 46.4 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain ABC_tran PF00005.27 EWM24332.1 - 1.7e-28 99.8 0.0 3.3e-15 56.8 0.0 3.2 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EWM24332.1 - 5.6e-07 29.7 0.1 0.27 11.0 0.0 3.8 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EWM24332.1 - 7.2e-07 28.9 0.0 0.17 11.3 0.0 2.9 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 EWM24332.1 - 6e-05 23.6 0.1 0.077 13.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EWM24332.1 - 0.00021 21.0 0.0 0.26 11.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.6 EWM24332.1 - 0.0005 20.3 0.0 2.9 8.2 0.0 3.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 EWM24332.1 - 0.00081 19.8 3.3 0.14 12.5 0.5 4.0 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EWM24332.1 - 0.0013 19.0 0.5 5.2 7.4 0.0 3.4 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 EWM24332.1 - 0.0021 18.0 0.2 0.28 11.1 0.0 2.7 3 0 0 3 3 3 1 RsgA GTPase NACHT PF05729.12 EWM24332.1 - 0.0022 18.0 3.5 3.5 7.5 0.0 4.0 4 1 0 4 4 4 1 NACHT domain TsaE PF02367.17 EWM24332.1 - 0.0039 17.2 0.1 1.6 8.8 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 EWM24332.1 - 0.0087 16.6 0.2 1.1 9.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EWM24332.1 - 0.014 15.8 0.0 6.3 7.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 EWM24332.1 - 0.015 15.4 0.1 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EWM24332.1 - 0.024 14.4 0.4 3 7.6 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein MMR_HSR1 PF01926.23 EWM24332.1 - 0.034 14.2 0.0 14 5.8 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Thymidylate_kin PF02223.17 EWM24332.1 - 0.071 12.8 0.4 0.58 9.8 0.2 2.3 2 0 0 2 2 2 0 Thymidylate kinase AAA_13 PF13166.6 EWM24332.1 - 0.11 11.1 0.0 5.5 5.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EWM24332.1 - 0.14 12.2 0.0 21 5.1 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_15 PF13175.6 EWM24332.1 - 0.16 11.6 0.0 0.87 9.2 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain ATP_bind_1 PF03029.17 EWM24332.1 - 0.22 11.3 0.0 3.4 7.4 0.1 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Trigger_N PF05697.13 EWM24333.1 - 1.1e-24 87.4 0.2 1.1e-24 87.4 0.2 2.7 2 1 2 4 4 4 1 Bacterial trigger factor protein (TF) Trigger_C PF05698.14 EWM24333.1 - 1.4e-08 34.9 11.7 4.2e-08 33.4 11.7 1.8 1 0 0 1 1 1 1 Bacterial trigger factor protein (TF) C-terminus TBCA PF02970.16 EWM24337.1 - 5.7e-28 97.1 4.5 8e-28 96.6 4.5 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A DUF4355 PF14265.6 EWM24337.1 - 0.42 10.9 7.3 0.25 11.6 4.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4355) CobN-Mg_chel PF02514.16 EWM24338.1 - 8.7e-289 960.9 0.0 1.3e-250 834.5 0.0 2.1 2 0 0 2 2 2 2 CobN/Magnesium Chelatase DUF3479 PF11965.8 EWM24338.1 - 2.1e-47 161.2 0.0 4.4e-47 160.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3479) RRP14 PF15459.6 EWM24339.1 - 2.2e-15 57.0 4.3 2.2e-15 57.0 4.3 3.4 3 0 0 3 3 3 1 60S ribosome biogenesis protein Rrp14 Nop14 PF04147.12 EWM24339.1 - 0.039 12.2 30.9 0.051 11.8 30.9 1.1 1 0 0 1 1 1 0 Nop14-like family Macoilin PF09726.9 EWM24339.1 - 0.14 10.7 10.0 0.18 10.3 10.0 1.0 1 0 0 1 1 1 0 Macoilin family CDC27 PF09507.10 EWM24339.1 - 0.14 11.5 22.5 0.16 11.4 22.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PPP4R2 PF09184.11 EWM24339.1 - 1.9 8.0 20.1 2.8 7.5 20.1 1.2 1 0 0 1 1 1 0 PPP4R2 GMC_oxred_N PF00732.19 EWM24341.1 - 7.8e-51 173.2 0.0 1.1e-50 172.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EWM24341.1 - 1.5e-26 93.6 0.1 2.4e-26 93.0 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EWM24341.1 - 0.00078 19.6 0.0 0.0021 18.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EWM24341.1 - 0.0022 17.1 0.7 0.0033 16.5 0.7 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 EWM24341.1 - 0.0064 16.1 0.2 0.023 14.3 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EWM24341.1 - 0.013 14.7 0.2 0.03 13.6 0.2 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 EWM24341.1 - 0.016 14.4 0.1 0.033 13.4 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EWM24341.1 - 0.096 11.7 1.1 0.23 10.5 1.1 1.8 1 1 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 EWM24341.1 - 0.1 11.3 0.2 0.25 10.0 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.19 EWM24341.1 - 0.15 11.2 0.3 0.24 10.6 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain GMC_oxred_N PF00732.19 EWM24342.1 - 1.2e-38 133.2 0.0 1.8e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EWM24342.1 - 9.9e-27 94.2 0.1 1.6e-26 93.6 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase adh_short PF00106.25 EWM24343.1 - 5.1e-39 133.7 0.4 7.2e-39 133.3 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EWM24343.1 - 2.9e-25 89.2 0.3 4.1e-25 88.7 0.3 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM24343.1 - 1.9e-08 34.5 0.3 3.1e-08 33.7 0.3 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EWM24343.1 - 0.00016 21.2 0.0 0.00045 19.7 0.0 1.7 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) DEK_C PF08766.11 EWM24343.1 - 0.15 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 DEK C terminal domain SPC22 PF04573.12 EWM24344.1 - 2.7e-42 144.2 0.2 3.5e-42 143.8 0.2 1.1 1 0 0 1 1 1 1 Signal peptidase subunit GRP PF07172.11 EWM24345.1 - 0.004 17.8 1.0 0.0057 17.3 1.0 1.3 1 0 0 1 1 1 1 Glycine rich protein family Rsc14 PF08586.10 EWM24345.1 - 0.039 14.7 0.7 0.07 13.9 0.7 1.4 1 0 0 1 1 1 0 RSC complex, Rsc14/Ldb7 subunit DUF2201_N PF13203.6 EWM24345.1 - 0.16 11.6 2.0 0.17 11.5 2.0 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Connexin PF00029.19 EWM24345.1 - 1.3 8.7 3.0 1.9 8.2 0.5 2.0 2 0 0 2 2 2 0 Connexin Ank_2 PF12796.7 EWM24346.1 - 8.8e-16 58.3 0.0 6.8e-07 29.8 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EWM24346.1 - 2.6e-14 53.4 0.0 1.9e-06 28.3 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EWM24346.1 - 1.2e-12 47.8 0.2 1.6e-07 31.4 0.0 3.8 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EWM24346.1 - 1.3e-12 46.7 0.2 0.00085 19.6 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EWM24346.1 - 5.8e-12 45.5 4.6 3e-06 27.4 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeat PhyH PF05721.13 EWM24347.1 - 7.7e-15 55.7 0.1 8e-14 52.4 0.1 2.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Ctr PF04145.15 EWM24349.1 - 9.9e-19 68.4 0.4 1.2e-18 68.1 0.4 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Myb_DNA-bind_7 PF15963.5 EWM24350.1 - 4.8e-21 74.4 0.1 6.8e-21 74.0 0.1 1.1 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 EWM24350.1 - 0.00031 20.9 0.0 0.0005 20.2 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EWM24350.1 - 0.01 16.0 0.0 0.016 15.5 0.0 1.2 1 0 0 1 1 1 0 Myb-like DNA-binding domain Zn_clus PF00172.18 EWM24351.1 - 0.00021 21.3 7.1 0.00038 20.5 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 EWM24351.1 - 0.00076 19.6 34.9 0.0012 19.0 34.9 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 EWM24351.1 - 0.022 14.4 41.1 0.036 13.7 41.1 1.3 1 0 0 1 1 1 0 Spt20 family Suf PF05843.14 EWM24351.1 - 0.13 12.2 11.8 0.23 11.4 11.8 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DDHD PF02862.17 EWM24351.1 - 0.22 11.6 8.7 0.57 10.3 8.7 1.6 1 0 0 1 1 1 0 DDHD domain Tim54 PF11711.8 EWM24351.1 - 0.34 9.7 12.2 0.53 9.0 12.2 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TERB2 PF15101.6 EWM24351.1 - 0.5 10.4 16.2 0.81 9.7 16.2 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 CPSF100_C PF13299.6 EWM24351.1 - 0.88 9.7 9.2 1.8 8.7 9.2 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Neur_chan_memb PF02932.16 EWM24351.1 - 0.99 9.4 7.5 1.8 8.6 7.5 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 EWM24351.1 - 1.2 8.9 11.7 2 8.2 11.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EOS1 PF12326.8 EWM24351.1 - 1.6 8.6 2.7 2.6 7.9 2.7 1.3 1 0 0 1 1 1 0 N-glycosylation protein eIF-3_zeta PF05091.12 EWM24351.1 - 1.7 7.6 18.7 3.2 6.6 18.7 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Lin-8 PF03353.15 EWM24351.1 - 1.8 8.1 19.4 2.7 7.4 19.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Presenilin PF01080.17 EWM24351.1 - 3.3 6.4 16.8 5.6 5.6 16.8 1.2 1 0 0 1 1 1 0 Presenilin SpoIIP PF07454.11 EWM24351.1 - 4.3 6.7 15.0 7.2 6.0 15.0 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) SLC12 PF03522.15 EWM24351.1 - 4.5 6.2 11.8 6.7 5.6 11.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF4770 PF15994.5 EWM24351.1 - 4.8 7.4 14.7 8.2 6.6 14.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Paf1 PF03985.13 EWM24351.1 - 6.4 5.7 18.9 10 5.0 18.9 1.1 1 0 0 1 1 1 0 Paf1 DUF2722 PF10846.8 EWM24351.1 - 6.4 5.6 34.3 15 4.4 34.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) GREB1 PF15782.5 EWM24351.1 - 6.7 3.7 13.5 9 3.3 13.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Endostatin PF06482.11 EWM24351.1 - 8.6 5.7 16.1 13 5.1 16.1 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Fe_hyd_lg_C PF02906.14 EWM24352.1 - 4.8e-82 275.3 0.0 5.9e-82 275.0 0.0 1.1 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 EWM24352.1 - 5.3e-23 80.9 1.2 8.7e-23 80.2 1.2 1.3 1 0 0 1 1 1 1 Iron hydrogenase small subunit DUF21 PF01595.20 EWM24354.1 - 1.8e-34 119.0 3.3 3.1e-34 118.2 3.3 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CorC_HlyC PF03471.17 EWM24354.1 - 5.3e-17 61.6 0.7 1.3e-16 60.3 0.3 1.9 2 0 0 2 2 2 1 Transporter associated domain CBS PF00571.28 EWM24354.1 - 1.8e-14 53.9 0.8 3e-07 30.8 0.0 3.2 3 0 0 3 3 3 2 CBS domain WD40 PF00400.32 EWM24356.1 - 0.0013 19.5 0.0 17 6.5 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat Radical_SAM PF04055.21 EWM24357.1 - 5.7e-13 49.6 0.0 1.1e-12 48.6 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily SBP_bac_5 PF00496.22 EWM24357.1 - 0.24 10.3 0.0 0.35 9.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle Radical_SAM PF04055.21 EWM24358.1 - 3.1e-13 50.5 0.0 6.3e-13 49.4 0.0 1.5 2 0 0 2 2 2 1 Radical SAM superfamily SBP_bac_5 PF00496.22 EWM24358.1 - 0.17 10.8 0.0 0.23 10.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle BATS PF06968.13 EWM24359.1 - 6e-22 77.6 0.0 1.2e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 EWM24359.1 - 5.7e-07 30.1 0.0 1.7e-06 28.5 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Pam16 PF03656.13 EWM24359.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Pam16 PQQ_2 PF13360.6 EWM24360.1 - 0.039 13.5 0.3 0.81 9.2 0.1 2.7 3 1 0 3 3 3 0 PQQ-like domain PQQ_2 PF13360.6 EWM24361.1 - 0.033 13.8 0.3 0.78 9.3 0.1 2.7 3 1 0 3 3 3 0 PQQ-like domain HydF_tetramer PF18133.1 EWM24362.1 - 2.3e-29 101.5 0.0 5.1e-29 100.4 0.0 1.6 1 0 0 1 1 1 1 Hydrogen maturase F tetramerization domain HydF_dimer PF18128.1 EWM24362.1 - 0.016 15.3 0.3 0.22 11.6 0.2 2.7 2 1 0 2 2 2 0 Hydrogen maturase F dimerization domain CheB_methylest PF01339.17 EWM24362.1 - 0.051 13.3 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 CheB methylesterase XH PF03469.14 EWM24364.1 - 3.3e-07 30.3 0.1 7.2e-07 29.2 0.0 1.6 2 0 0 2 2 2 1 XH domain FA_FANCE PF11510.8 EWM24365.1 - 4.2e-06 26.3 0.5 0.0016 17.9 0.5 2.2 2 0 0 2 2 2 2 Fanconi Anaemia group E protein FANCE FA_FANCE PF11510.8 EWM24366.1 - 0.00012 21.6 1.4 0.0014 18.1 0.5 2.1 2 0 0 2 2 2 2 Fanconi Anaemia group E protein FANCE MutS_I PF01624.20 EWM24367.1 - 1.4e-12 47.9 0.0 2.3e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 MutS domain I SIS PF01380.22 EWM24368.1 - 2.4e-35 121.2 0.6 5.5e-17 61.9 0.0 3.2 3 0 0 3 3 3 2 SIS domain GATase_6 PF13522.6 EWM24368.1 - 5.1e-22 78.5 0.1 1.5e-21 77.0 0.1 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EWM24368.1 - 1.7e-14 53.7 0.0 4.5e-14 52.4 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EWM24368.1 - 0.004 16.1 1.2 0.008 15.1 1.1 1.5 1 1 0 1 1 1 1 Glutamine amidotransferases class-II Epimerase PF01370.21 EWM24370.1 - 1.2e-20 74.1 0.0 8.9e-19 67.9 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EWM24370.1 - 9.5e-15 54.8 0.0 2e-07 30.8 0.0 2.1 1 1 1 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EWM24370.1 - 4.6e-12 46.2 0.0 7.5e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EWM24370.1 - 3.7e-07 29.9 0.0 5.3e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 EWM24370.1 - 0.00016 20.8 0.0 0.0016 17.6 0.0 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain DUF2686 PF10887.8 EWM24370.1 - 0.032 13.2 0.0 0.048 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2686) Pyr_redox_2 PF07992.14 EWM24370.1 - 0.064 12.5 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_transf_4 PF13439.6 EWM24370.1 - 0.07 13.1 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Glycosyltransferase Family 4 DDE_Tnp_4 PF13359.6 EWM24373.1 - 0.0027 17.4 0.0 0.58 9.8 0.0 2.1 2 0 0 2 2 2 2 DDE superfamily endonuclease Glutaredoxin PF00462.24 EWM24375.1 - 1.1e-15 57.6 0.0 1.5e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 EWM24375.1 - 0.029 14.8 0.0 0.05 14.0 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EWM24375.1 - 0.032 14.5 0.0 0.051 13.9 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DSBA PF01323.20 EWM24375.1 - 0.094 12.5 0.1 4.8 6.9 0.1 2.1 2 0 0 2 2 2 0 DSBA-like thioredoxin domain Tyr-DNA_phospho PF06087.12 EWM24376.1 - 4.9e-28 98.2 0.0 6.7e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase MutS_V PF00488.21 EWM24377.1 - 9.5e-35 120.3 0.0 5.4e-24 85.3 0.0 2.3 2 0 0 2 2 2 2 MutS domain V AAA_23 PF13476.6 EWM24377.1 - 0.0068 16.9 0.0 0.011 16.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain GIY-YIG PF01541.24 EWM24377.1 - 0.013 15.7 0.0 0.024 14.9 0.0 1.3 1 0 0 1 1 1 0 GIY-YIG catalytic domain AAA_29 PF13555.6 EWM24377.1 - 0.033 13.9 0.2 0.082 12.7 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ank_2 PF12796.7 EWM24378.1 - 2.7e-15 56.7 0.7 2.9e-10 40.6 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EWM24378.1 - 2.7e-13 50.2 0.4 3.9e-06 27.3 0.2 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EWM24378.1 - 2.8e-11 43.4 0.1 2.1e-06 27.9 0.0 2.9 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EWM24378.1 - 4.6e-10 38.9 0.6 0.022 15.3 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EWM24378.1 - 0.00054 20.3 5.7 2 9.0 1.1 4.1 4 0 0 4 4 4 2 Ankyrin repeat Poty_PP PF08440.10 EWM24378.1 - 0.025 13.7 0.1 0.034 13.2 0.1 1.2 1 0 0 1 1 1 0 Potyviridae polyprotein Sulfotransfer_4 PF17784.1 EWM24378.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase domain MSP PF01716.18 EWM24379.1 - 3.5e-98 327.6 0.3 4.1e-98 327.4 0.3 1.1 1 0 0 1 1 1 1 Manganese-stabilising protein / photosystem II polypeptide MSP PF01716.18 EWM24380.1 - 1.9e-53 181.2 0.0 2.2e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 Manganese-stabilising protein / photosystem II polypeptide Amidohydro_1 PF01979.20 EWM24381.1 - 8.6e-52 176.5 0.0 8.9e-38 130.5 0.0 3.0 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 EWM24381.1 - 2.6e-07 30.5 1.6 3.5e-05 23.5 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 EWM24381.1 - 2.8e-05 23.6 0.1 4.6e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase QRPTase_C PF01729.19 EWM24382.1 - 3.2e-57 193.0 0.0 4.5e-57 192.5 0.0 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 EWM24382.1 - 1.3e-13 50.8 0.1 4.4e-06 26.7 0.1 2.5 2 0 0 2 2 2 2 Quinolinate phosphoribosyl transferase, N-terminal domain Pkinase PF00069.25 EWM24383.1 - 9.3e-66 221.9 0.0 1.2e-65 221.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM24383.1 - 1.2e-32 113.3 0.0 1.8e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EWM24383.1 - 0.0014 18.1 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EWM24383.1 - 0.0053 15.8 0.0 0.0086 15.1 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EWM24383.1 - 0.036 14.0 0.1 0.085 12.8 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EWM24383.1 - 0.24 10.1 0.0 0.24 10.1 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase Presenilin PF01080.17 EWM24383.1 - 0.34 9.6 0.4 0.48 9.1 0.4 1.1 1 0 0 1 1 1 0 Presenilin BLM_N PF16202.5 EWM24384.1 - 0.016 14.3 0.9 0.019 14.1 0.9 1.1 1 0 0 1 1 1 0 N-terminal region of Bloom syndrome protein Phospho_p8 PF10195.9 EWM24384.1 - 0.035 14.6 5.1 0.05 14.1 5.1 1.2 1 0 0 1 1 1 0 DNA-binding nuclear phosphoprotein p8 Afi1 PF07792.12 EWM24384.1 - 0.042 14.3 1.4 0.049 14.1 1.4 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking FAM176 PF14851.6 EWM24384.1 - 0.22 11.2 0.9 0.26 10.9 0.9 1.1 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.6 EWM24384.1 - 5.3 7.5 9.2 6.7 7.2 9.2 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pro_isomerase PF00160.21 EWM24385.1 - 2.1e-29 102.8 0.0 3.3e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD AF-4 PF05110.13 EWM24385.1 - 0.17 9.9 17.0 0.21 9.6 17.0 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SR-25 PF10500.9 EWM24385.1 - 0.51 9.9 19.5 0.79 9.3 19.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 EWM24385.1 - 1.1 8.0 6.9 1.4 7.7 6.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDK2AP PF09806.9 EWM24385.1 - 2.5 8.1 6.6 4.1 7.4 6.6 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Macoilin PF09726.9 EWM24385.1 - 8.4 4.8 11.9 14 4.1 11.9 1.2 1 0 0 1 1 1 0 Macoilin family FAM199X PF15814.5 EWM24385.1 - 9.9 5.1 16.0 16 4.4 16.0 1.2 1 0 0 1 1 1 0 Protein family FAM199X Pro_isomerase PF00160.21 EWM24386.1 - 9.1e-30 104.0 0.0 1.1e-29 103.8 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ras PF00071.22 EWM24387.1 - 5.1e-27 94.4 0.0 3.2e-26 91.9 0.0 2.0 1 1 0 1 1 1 1 Ras family GTP_EFTU PF00009.27 EWM24387.1 - 3.4e-06 26.7 0.0 9.1e-06 25.3 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Roc PF08477.13 EWM24387.1 - 6.8e-05 23.1 0.0 0.00055 20.1 0.0 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EWM24387.1 - 8.2e-05 22.7 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EWM24387.1 - 0.0051 16.2 0.0 0.0089 15.4 0.0 1.4 1 1 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 EWM24387.1 - 0.0077 16.2 0.0 1.3 9.0 0.1 2.3 2 1 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EWM24387.1 - 0.012 15.7 0.0 0.48 10.5 0.0 2.2 2 0 0 2 2 2 0 Dynamin family ABC_tran PF00005.27 EWM24387.1 - 0.059 13.9 0.0 0.083 13.4 0.0 1.3 1 0 0 1 1 1 0 ABC transporter TniB PF05621.11 EWM24387.1 - 0.093 12.1 0.1 0.83 9.0 0.1 2.1 1 1 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 EWM24387.1 - 0.1 12.9 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EWM24387.1 - 0.11 12.9 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Semialdhyde_dh PF01118.24 EWM24388.1 - 3.9e-06 27.3 0.0 6e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 EWM24388.1 - 4.8e-05 23.3 0.0 0.0001 22.3 0.0 1.6 1 1 1 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EWM24388.1 - 0.12 11.5 0.0 3.3 6.8 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein DUF1664 PF07889.12 EWM24394.1 - 0.0056 16.7 20.3 0.17 11.9 0.9 4.7 3 1 2 5 5 5 3 Protein of unknown function (DUF1664) DUF4482 PF14818.6 EWM24394.1 - 0.019 15.9 5.2 0.019 15.9 5.2 3.9 2 1 1 4 4 4 0 Domain of unknown function (DUF4482) Lectin_N PF03954.14 EWM24394.1 - 0.083 12.6 9.6 0.03 14.1 3.8 3.0 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain DUF2576 PF10845.8 EWM24394.1 - 0.093 12.3 0.9 0.25 11.0 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) Fib_alpha PF08702.10 EWM24394.1 - 2.5 8.3 19.4 6.4 7.0 4.6 4.6 4 1 0 4 4 4 0 Fibrinogen alpha/beta chain family BSD PF03909.17 EWM24396.1 - 2.6e-05 24.1 0.0 6.9e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 BSD domain FTA4 PF13093.6 EWM24396.1 - 0.037 13.9 0.2 0.05 13.5 0.2 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 ATP-synt_B PF00430.18 EWM24396.1 - 0.64 10.1 11.2 1.1 9.3 11.2 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Whirly PF08536.11 EWM24398.1 - 0.0025 17.7 0.0 0.006 16.4 0.0 1.6 1 1 0 1 1 1 1 Whirly transcription factor FPL PF09758.9 EWM24400.1 - 0.064 13.3 0.0 0.085 12.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein ADK PF00406.22 EWM24402.1 - 3.2e-10 40.3 0.0 3.9e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EWM24402.1 - 2.3e-07 31.3 0.0 2.9e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EWM24402.1 - 0.016 15.7 0.0 0.024 15.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain End_N_terminal PF12218.8 EWM24402.1 - 0.017 14.8 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase Thymidylate_kin PF02223.17 EWM24402.1 - 0.13 11.9 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Thymidylate kinase ELMO_CED12 PF04727.13 EWM24403.1 - 5.8e-29 101.5 0.0 7.8e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family Ion_trans PF00520.31 EWM24405.1 - 6.3e-17 61.6 1.0 1e-16 60.9 1.0 1.3 1 0 0 1 1 1 1 Ion transport protein ABC2_membrane_2 PF12679.7 EWM24405.1 - 0.33 10.2 4.6 0.24 10.6 2.2 1.8 2 0 0 2 2 2 0 ABC-2 family transporter protein BUD22 PF09073.10 EWM24406.1 - 0.066 12.5 2.2 0.088 12.1 2.2 1.1 1 0 0 1 1 1 0 BUD22 Ion_trans_2 PF07885.16 EWM24407.1 - 1.4e-06 28.1 5.0 2.1e-06 27.6 5.0 1.3 1 0 0 1 1 1 1 Ion channel Spc29 PF17082.5 EWM24407.1 - 0.03 14.2 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 Spindle Pole Component 29 DUF16 PF01519.16 EWM24407.1 - 0.1 13.1 5.1 0.13 12.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 YebO PF13974.6 EWM24407.1 - 1.5 9.0 8.5 3.2 7.9 1.2 3.0 3 0 0 3 3 3 0 YebO-like protein Spc29 PF17082.5 EWM24408.1 - 0.019 14.8 0.2 0.033 14.0 0.0 1.5 2 0 0 2 2 2 0 Spindle Pole Component 29 DUF16 PF01519.16 EWM24408.1 - 0.049 14.1 5.1 0.075 13.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF2201_N PF13203.6 EWM24410.1 - 0.81 9.2 7.7 1.3 8.6 7.7 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain NARP1 PF12569.8 EWM24410.1 - 2.7 6.8 4.9 3.5 6.4 4.9 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Peptidase_M16_M PF16187.5 EWM24412.1 - 6.1e-23 81.5 0.0 7.6e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 FAM176 PF14851.6 EWM24413.1 - 0.035 13.8 5.8 0.058 13.1 5.8 1.3 1 0 0 1 1 1 0 FAM176 family DUF2052 PF09747.9 EWM24413.1 - 0.048 13.8 8.8 0.057 13.6 8.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) HSP70 PF00012.20 EWM24413.1 - 0.068 11.4 9.6 1.2 7.2 9.6 2.0 1 1 0 1 1 1 0 Hsp70 protein Phage_T4_gp36 PF03903.13 EWM24413.1 - 0.085 12.8 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Phage T4 tail fibre NOA36 PF06524.12 EWM24413.1 - 0.27 10.5 5.2 0.31 10.3 5.2 1.1 1 0 0 1 1 1 0 NOA36 protein DUF4746 PF15928.5 EWM24413.1 - 0.45 9.9 8.3 0.54 9.6 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Radial_spoke PF04712.12 EWM24413.1 - 0.75 8.7 11.1 0.89 8.4 11.1 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein CDC45 PF02724.14 EWM24413.1 - 0.92 7.7 4.5 1.1 7.5 4.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Phage_Gp23 PF10669.9 EWM24413.1 - 1.3 9.4 8.4 1.9 8.8 8.4 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DUF3915 PF13054.6 EWM24413.1 - 1.5 8.9 6.4 2.3 8.2 6.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Paf1 PF03985.13 EWM24413.1 - 3.1 6.7 11.3 3.9 6.4 11.3 1.1 1 0 0 1 1 1 0 Paf1 DNA_pol_phi PF04931.13 EWM24413.1 - 4.3 5.3 11.9 5.5 5.0 11.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF4637 PF15470.6 EWM24413.1 - 7.2 6.3 12.5 11 5.7 12.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Methyltransf_23 PF13489.6 EWM24417.1 - 0.00062 19.6 0.0 0.0009 19.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM24417.1 - 0.082 12.7 0.0 0.089 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EWM24417.1 - 0.18 12.6 0.0 0.29 11.9 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Peptidase_S8 PF00082.22 EWM24418.1 - 1.6e-11 44.0 0.1 1.7e-11 43.9 0.1 1.0 1 0 0 1 1 1 1 Subtilase family Peptidase_S8 PF00082.22 EWM24419.1 - 0.00019 20.8 0.2 0.0002 20.7 0.2 1.0 1 0 0 1 1 1 1 Subtilase family DUF2020 PF09449.10 EWM24419.1 - 0.096 12.5 3.4 0.12 12.3 3.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF2020) DUF2007 PF09413.10 EWM24419.1 - 0.19 11.9 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative prokaryotic signal transducing protein ALMT PF11744.8 EWM24419.1 - 0.23 10.3 0.2 0.27 10.0 0.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Totivirus_coat PF05518.11 EWM24420.1 - 3.7 5.5 14.7 5.7 4.9 14.7 1.2 1 0 0 1 1 1 0 Totivirus coat protein Metallophos PF00149.28 EWM24421.1 - 2.9e-26 93.2 0.0 1.3e-25 91.2 0.0 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 EWM24421.1 - 9.9e-18 64.5 3.6 9.9e-18 64.5 3.6 1.9 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 EWM24421.1 - 3.4e-13 50.2 0.4 1.2e-12 48.4 0.4 2.0 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 EWM24421.1 - 1.6e-05 25.2 0.1 0.00025 21.3 0.1 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PhoD_N PF16655.5 EWM24421.1 - 0.089 13.3 0.1 0.23 12.0 0.1 1.7 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain Metallophos PF00149.28 EWM24423.1 - 4.1e-24 86.2 0.0 1.1e-23 84.8 0.0 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 EWM24423.1 - 2.4e-17 63.3 3.0 2.4e-17 63.3 3.0 1.9 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 EWM24423.1 - 9e-14 52.1 0.3 3e-13 50.4 0.3 1.9 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 EWM24423.1 - 4.4e-05 23.7 0.1 0.00069 19.8 0.1 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PhoD_N PF16655.5 EWM24423.1 - 0.1 13.2 0.1 0.26 11.8 0.1 1.7 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain zf-CCCH PF00642.24 EWM24424.1 - 0.0011 18.8 3.8 0.0019 18.0 3.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EWM24424.1 - 0.0038 17.9 0.3 0.0069 17.1 0.3 1.3 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 EWM24424.1 - 0.0087 16.1 5.4 0.014 15.4 5.4 1.3 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 EWM24424.1 - 0.013 15.3 2.9 0.021 14.6 2.9 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger PA28_alpha PF02251.18 EWM24425.1 - 0.0001 22.3 0.0 0.00016 21.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome activator pa28 alpha subunit RRM_1 PF00076.22 EWM24426.1 - 1.3e-17 63.4 0.0 1.3e-16 60.2 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EWM24426.1 - 0.00034 20.7 0.0 0.00076 19.6 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 EWM24426.1 - 0.084 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-CCCH_4 PF18044.1 EWM24427.1 - 0.0046 16.7 5.6 0.054 13.3 5.6 2.2 1 1 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EWM24427.1 - 0.022 14.8 1.0 0.022 14.8 1.0 2.3 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH_2 PF14608.6 EWM24427.1 - 0.074 13.6 3.6 0.34 11.4 3.6 2.0 1 1 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 EWM24427.1 - 0.37 10.8 4.8 0.33 10.9 0.9 2.3 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Tyrosinase PF00264.20 EWM24434.1 - 3.7e-06 27.4 3.2 0.0067 16.7 0.3 2.6 2 0 0 2 2 2 2 Common central domain of tyrosinase Helitron_like_N PF14214.6 EWM24441.1 - 0.0031 17.7 0.0 0.0034 17.6 0.0 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus MoaC PF01967.21 EWM24442.1 - 1.1e-46 158.3 0.0 1.6e-46 157.8 0.0 1.3 1 0 0 1 1 1 1 MoaC family F-box-like PF12937.7 EWM24444.1 - 2.8e-07 30.3 2.0 8.5e-06 25.6 0.3 2.4 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 EWM24444.1 - 0.039 13.8 0.8 0.063 13.2 0.0 1.9 2 0 0 2 2 2 0 F-box domain CDC45 PF02724.14 EWM24445.1 - 0.047 12.0 23.1 0.051 11.9 23.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EWM24445.1 - 0.07 11.4 18.1 0.073 11.3 18.1 1.3 1 0 0 1 1 1 0 Nop14-like family CDC27 PF09507.10 EWM24445.1 - 0.089 12.2 21.0 0.13 11.6 21.0 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RR_TM4-6 PF06459.12 EWM24445.1 - 0.38 10.5 15.6 0.55 10.0 15.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 EWM24445.1 - 0.58 8.9 13.0 0.65 8.7 13.0 1.1 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 EWM24445.1 - 1.6 6.8 8.0 1.8 6.6 8.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SLC12 PF03522.15 EWM24445.1 - 4.6 6.2 7.8 4.9 6.1 7.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DnaJ PF00226.31 EWM24446.1 - 1.7e-09 37.6 0.1 4.3e-09 36.4 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain Hairy_orange PF07527.13 EWM24447.1 - 0.094 12.9 0.3 0.2 11.9 0.3 1.5 1 0 0 1 1 1 0 Hairy Orange EHD_N PF16880.5 EWM24449.1 - 1.6e-15 56.7 0.3 2.1e-15 56.3 0.3 1.2 1 0 0 1 1 1 1 N-terminal EH-domain containing protein Dynamin_N PF00350.23 EWM24449.1 - 1.5e-07 31.6 0.0 2.1e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EWM24449.1 - 0.0095 16.0 0.0 0.02 15.0 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 EWM24449.1 - 0.038 14.2 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 EWM24450.1 - 4.8e-25 88.6 0.3 8.8e-25 87.7 0.1 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EWM24450.1 - 3.7e-06 27.4 3.3 2.4e-05 24.8 0.6 2.8 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 EWM24450.1 - 3.7e-05 23.9 0.8 0.0035 17.5 0.0 2.6 1 1 1 3 3 3 1 AAA domain AAA PF00004.29 EWM24450.1 - 5e-05 23.7 0.1 0.00018 21.9 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EWM24450.1 - 6.2e-05 23.3 1.0 0.00018 21.8 0.1 2.1 2 1 0 2 2 2 1 AAA domain ADK PF00406.22 EWM24450.1 - 7.9e-05 22.8 0.2 0.00071 19.7 0.0 2.2 2 1 1 3 3 3 1 Adenylate kinase T2SSE PF00437.20 EWM24450.1 - 0.0016 17.5 0.1 0.0029 16.7 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_11 PF13086.6 EWM24450.1 - 0.0027 17.5 0.2 0.034 13.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EWM24450.1 - 0.0028 17.9 1.1 0.012 15.9 0.3 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EWM24450.1 - 0.0035 17.7 0.3 0.0062 16.9 0.3 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 EWM24450.1 - 0.0036 17.6 0.3 0.0036 17.6 0.3 1.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EWM24450.1 - 0.0038 17.2 0.1 0.026 14.5 0.1 2.0 1 1 0 2 2 2 1 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 EWM24450.1 - 0.0063 16.4 0.5 0.015 15.2 0.1 1.8 2 0 0 2 2 2 1 NTPase AAA_23 PF13476.6 EWM24450.1 - 0.0099 16.4 0.7 0.021 15.3 0.6 1.5 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EWM24450.1 - 0.016 14.5 1.2 0.15 11.4 0.2 2.5 2 1 1 3 3 3 0 Zeta toxin AAA_24 PF13479.6 EWM24450.1 - 0.016 14.9 1.3 0.026 14.3 0.2 1.8 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EWM24450.1 - 0.024 14.0 0.0 0.049 13.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_30 PF13604.6 EWM24450.1 - 0.024 14.4 0.1 0.044 13.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EWM24450.1 - 0.048 13.0 1.0 0.07 12.5 0.1 1.6 2 0 0 2 2 2 0 KaiC Sigma54_activ_2 PF14532.6 EWM24450.1 - 0.049 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.26 EWM24450.1 - 0.071 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain RuvB_N PF05496.12 EWM24450.1 - 0.084 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain KTI12 PF08433.10 EWM24450.1 - 0.084 12.3 0.1 0.29 10.5 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 TsaE PF02367.17 EWM24450.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 EWM24450.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 EWM24450.1 - 0.19 12.3 0.4 0.3 11.6 0.4 1.7 1 1 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 EWM24450.1 - 0.37 10.9 1.1 1.5 8.9 1.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase ThiF PF00899.21 EWM24451.1 - 7.7e-12 45.1 0.0 1.2e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 EWM24451.1 - 0.003 17.8 0.5 0.005 17.1 0.5 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 EWM24451.1 - 0.0044 17.3 0.2 0.0077 16.5 0.2 1.4 1 0 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.20 EWM24451.1 - 0.0088 16.1 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 EWM24451.1 - 0.035 13.3 0.3 0.048 12.9 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 EWM24451.1 - 0.055 12.8 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Ldh_1_N PF00056.23 EWM24451.1 - 0.13 12.4 0.1 0.18 11.9 0.1 1.2 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ApbA PF02558.16 EWM24451.1 - 0.14 11.7 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF4574 PF15141.6 EWM24451.1 - 0.15 12.0 0.0 3.5 7.6 0.0 2.1 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 3Beta_HSD PF01073.19 EWM24451.1 - 0.18 10.8 0.4 0.24 10.4 0.4 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family zf-C3HC4_4 PF15227.6 EWM24452.1 - 0.00087 19.4 4.6 0.00087 19.4 4.6 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EWM24452.1 - 0.0017 18.3 7.7 0.0017 18.3 7.7 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EWM24452.1 - 0.01 15.6 2.2 0.01 15.6 2.2 3.9 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EWM24452.1 - 0.012 15.4 5.1 0.012 15.4 5.1 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Dynamin_N PF00350.23 EWM24454.1 - 1.2e-05 25.4 0.0 1.6e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EWM24454.1 - 0.0001 22.3 0.0 0.00015 21.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EWM24454.1 - 0.0074 15.8 0.1 0.019 14.5 0.2 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain His_Phos_1 PF00300.22 EWM24455.1 - 6.5e-08 32.5 0.0 7.7e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Apt1 PF10351.9 EWM24456.1 - 0.058 12.2 10.3 0.05 12.5 10.3 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 EWM24456.1 - 0.15 10.6 10.2 0.13 10.8 10.2 1.0 1 0 0 1 1 1 0 Macoilin family RSRP PF17069.5 EWM24456.1 - 0.42 10.2 43.8 0.48 10.0 43.8 1.1 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 SPX PF03105.19 EWM24456.1 - 3.3 7.5 15.9 3.3 7.5 15.9 1.1 1 0 0 1 1 1 0 SPX domain DUF4614 PF15391.6 EWM24456.1 - 4.2 7.3 22.3 5.4 7.0 22.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Peroxin-3 PF04882.12 EWM24456.1 - 5.5 5.9 13.5 6.8 5.6 13.5 1.1 1 0 0 1 1 1 0 Peroxin-3 CAP_N PF01213.19 EWM24458.1 - 0.0056 16.2 1.1 0.009 15.5 1.1 1.5 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal Syndecan PF01034.20 EWM24458.1 - 0.14 12.1 0.4 0.26 11.2 0.4 1.4 1 0 0 1 1 1 0 Syndecan domain Mito_fiss_reg PF05308.11 EWM24458.1 - 3.3 7.7 6.7 5.3 7.1 6.7 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator TauE PF01925.19 EWM24459.1 - 1.1e-05 25.2 0.2 1.9e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 Sulfite exporter TauE/SafE DLH PF01738.18 EWM24460.1 - 7.9e-10 38.7 0.0 1e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family FAM176 PF14851.6 EWM24460.1 - 0.27 10.9 5.0 0.53 9.9 5.0 1.6 1 0 0 1 1 1 0 FAM176 family Myc_N PF01056.18 EWM24460.1 - 0.49 10.2 4.1 0.66 9.8 4.1 1.2 1 0 0 1 1 1 0 Myc amino-terminal region RNA_pol_3_Rpc31 PF11705.8 EWM24460.1 - 2.7 8.2 14.0 4.2 7.5 14.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DNA_pol_phi PF04931.13 EWM24460.1 - 3.6 5.6 11.0 5.1 5.1 11.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Pox_Ag35 PF03286.14 EWM24460.1 - 4.5 7.0 8.3 7.6 6.3 8.3 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SAP PF02037.27 EWM24461.1 - 3.9e-10 39.3 0.7 3.9e-10 39.3 0.7 1.7 2 0 0 2 2 2 1 SAP domain Hydrolase_3 PF08282.12 EWM24462.1 - 9.5e-07 28.8 0.0 0.0031 17.3 0.0 3.0 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EWM24462.1 - 0.00081 19.0 0.0 0.0031 17.1 0.0 1.9 2 1 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase ISPD_C PF18706.1 EWM24462.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain Sulfate_transp PF00916.20 EWM24463.1 - 1.1e-83 281.1 16.1 1.6e-83 280.6 15.2 1.7 2 0 0 2 2 2 1 Sulfate permease family STAS PF01740.21 EWM24463.1 - 1.3e-19 70.0 1.2 1.7e-19 69.6 0.1 1.7 2 0 0 2 2 2 1 STAS domain STAS_2 PF13466.6 EWM24463.1 - 4.9e-05 23.6 0.1 0.00015 22.1 0.1 1.8 1 0 0 1 1 1 1 STAS domain PRMT5_C PF17286.2 EWM24463.1 - 0.018 15.0 0.0 0.029 14.2 0.0 1.2 1 0 0 1 1 1 0 PRMT5 oligomerisation domain Sulfate_transp PF00916.20 EWM24464.1 - 7.4e-84 281.7 15.2 1e-83 281.2 15.2 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EWM24464.1 - 0.00023 20.8 0.1 0.00066 19.3 0.0 1.8 2 0 0 2 2 2 1 STAS domain PRMT5_C PF17286.2 EWM24464.1 - 0.014 15.2 0.1 0.023 14.6 0.1 1.2 1 0 0 1 1 1 0 PRMT5 oligomerisation domain Urm1 PF09138.11 EWM24466.1 - 0.058 13.7 0.1 9.5 6.7 0.0 2.8 1 1 2 3 3 3 0 Urm1 (Ubiquitin related modifier) FtsK_alpha PF17854.1 EWM24466.1 - 0.18 12.0 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 FtsK alpha domain PT PF04886.12 EWM24468.1 - 2.6e-21 74.9 178.8 0.004 16.7 9.3 10.5 1 1 5 6 6 6 3 PT repeat DUF543 PF04418.12 EWM24469.1 - 1.7e-08 34.3 0.0 2.5e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF543) MAGUK_N_PEST PF10608.9 EWM24471.1 - 0.18 12.3 2.2 0.25 11.8 2.2 1.2 1 0 0 1 1 1 0 Polyubiquitination (PEST) N-terminal domain of MAGUK Peptidase_M41 PF01434.18 EWM24473.1 - 6.8e-65 218.5 0.3 1e-64 217.9 0.3 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EWM24473.1 - 9.5e-42 142.5 0.0 1.8e-41 141.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EWM24473.1 - 3.2e-14 52.4 0.3 1.1e-13 50.7 0.3 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 EWM24473.1 - 0.00028 21.2 0.0 0.052 13.8 0.1 2.7 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 EWM24473.1 - 0.0024 17.9 0.2 0.052 13.6 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EWM24473.1 - 0.0033 16.7 0.1 0.0071 15.6 0.1 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 EWM24473.1 - 0.0074 16.4 0.1 0.032 14.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 EWM24473.1 - 0.0078 16.0 0.0 0.021 14.6 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein RuvB_N PF05496.12 EWM24473.1 - 0.013 15.2 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EWM24473.1 - 0.017 15.5 0.3 0.43 10.9 0.1 2.8 1 1 0 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.21 EWM24473.1 - 0.017 14.5 0.1 0.09 12.1 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 EWM24473.1 - 0.024 15.1 0.3 0.37 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EWM24473.1 - 0.027 14.6 0.0 0.062 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain ADAM_CR_2 PF17771.1 EWM24474.1 - 0.25 11.9 0.2 0.25 11.9 0.2 2.8 3 1 0 3 3 3 0 ADAM cysteine-rich domain zf-CCCH_2 PF14608.6 EWM24474.1 - 0.33 11.5 0.8 6.7 7.3 0.1 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Ribosomal_L16 PF00252.18 EWM24475.1 - 2.5e-37 127.8 1.1 3e-37 127.6 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Mito_carr PF00153.27 EWM24477.1 - 4.6e-20 71.3 6.1 1.4e-15 56.9 0.2 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein Proteasome PF00227.26 EWM24478.1 - 2.2e-11 43.6 0.0 2.5e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF1997 PF09366.10 EWM24481.1 - 8.1e-14 52.0 0.1 2.3e-13 50.6 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1997) SfLAP PF11139.8 EWM24484.1 - 0.0031 17.0 0.0 0.013 14.9 0.0 2.1 1 1 1 2 2 2 1 Sap, sulfolipid-1-addressing protein HupE_UreJ_2 PF13795.6 EWM24484.1 - 0.014 15.0 10.6 0.017 14.8 1.4 3.3 2 1 2 4 4 4 0 HupE / UreJ protein Abhydrolase_9_N PF15420.6 EWM24484.1 - 0.033 14.2 1.8 0.3 11.1 0.2 2.2 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus GIY-YIG PF01541.24 EWM24484.1 - 0.16 12.3 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 GIY-YIG catalytic domain Tetraspanin PF00335.20 EWM24484.1 - 0.23 11.2 1.8 16 5.2 0.7 2.4 2 0 0 2 2 2 0 Tetraspanin family DUF4131 PF13567.6 EWM24484.1 - 0.24 11.0 1.7 0.52 9.9 0.0 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) DUF308 PF03729.13 EWM24484.1 - 0.39 11.1 15.2 0.62 10.4 2.5 4.1 3 2 1 4 4 4 0 Short repeat of unknown function (DUF308) TctB PF07331.11 EWM24484.1 - 1.1 9.6 6.9 2.5 8.4 0.8 2.8 2 2 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Trp_oprn_chp PF09534.10 EWM24484.1 - 2 8.2 0.0 2 8.2 0.0 3.0 3 1 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Mog1 PF04603.12 EWM24485.1 - 8.4e-38 129.9 0.0 2.9e-37 128.1 0.0 1.8 2 0 0 2 2 2 1 Ran-interacting Mog1 protein DUF1816 PF08846.10 EWM24485.1 - 0.16 12.0 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1816) GCP_N_terminal PF17681.1 EWM24487.1 - 8.6e-14 51.9 0.0 9.5e-14 51.7 0.0 1.0 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Thioesterase PF00975.20 EWM24488.1 - 1.6e-13 51.3 0.0 9.3e-13 48.8 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain adh_short PF00106.25 EWM24489.1 - 4.7e-35 120.8 0.0 6e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EWM24489.1 - 5.5e-22 78.5 0.0 8.5e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM24489.1 - 6.7e-07 29.4 0.1 1.6e-06 28.2 0.1 1.6 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EWM24489.1 - 0.0079 15.4 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein UPF0128 PF03673.13 EWM24489.1 - 0.011 15.3 0.0 0.061 12.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0128) Epimerase PF01370.21 EWM24489.1 - 0.013 15.0 0.0 0.14 11.6 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EWM24489.1 - 0.015 14.7 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) adh_short PF00106.25 EWM24490.1 - 6.2e-35 120.4 0.0 7.8e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EWM24490.1 - 7.4e-22 78.1 0.0 1.1e-21 77.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM24490.1 - 8.9e-07 29.0 0.1 2e-06 27.9 0.1 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EWM24490.1 - 0.01 15.0 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 EWM24490.1 - 0.016 14.7 0.0 0.16 11.4 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EWM24490.1 - 0.018 14.4 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) CDC45 PF02724.14 EWM24493.1 - 3 6.0 9.3 4.1 5.6 9.3 1.2 1 0 0 1 1 1 0 CDC45-like protein LAP1C PF05609.12 EWM24493.1 - 4.6 6.2 6.7 5.7 5.9 6.7 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Aldedh PF00171.22 EWM24499.1 - 9.6e-35 120.0 0.1 1e-34 119.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF885 PF05960.11 EWM24499.1 - 0.11 12.1 0.3 0.16 11.6 0.3 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) NTP_transf_2 PF01909.23 EWM24501.1 - 0.045 14.1 0.0 0.083 13.2 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyltransferase domain PAP_assoc PF03828.19 EWM24503.1 - 4.1e-11 42.9 0.0 1.1e-10 41.6 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase OAS1_C PF10421.9 EWM24503.1 - 0.053 13.0 0.1 0.088 12.3 0.1 1.3 1 0 0 1 1 1 0 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus LRR_4 PF12799.7 EWM24504.1 - 1.9e-08 34.5 11.2 0.00021 21.6 0.1 4.1 2 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EWM24504.1 - 2.5e-06 27.2 11.9 0.0067 16.2 1.4 3.1 3 0 0 3 3 3 2 Leucine rich repeat LRR_9 PF14580.6 EWM24504.1 - 0.00029 20.4 2.9 0.033 13.7 0.2 3.3 1 1 2 3 3 3 2 Leucine-rich repeat BLACT_WH PF17778.1 EWM24504.1 - 0.16 12.0 0.3 0.16 12.0 0.3 2.0 3 0 0 3 3 3 0 Beta-lactamase associated winged helix domain LRR_1 PF00560.33 EWM24504.1 - 1.6 9.6 13.1 40 5.3 0.1 4.8 5 0 0 5 5 5 0 Leucine Rich Repeat HEAT PF02985.22 EWM24510.1 - 0.072 13.4 0.3 11 6.6 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat CactinC_cactus PF09732.9 EWM24511.1 - 7.8e-59 197.1 8.0 9.4e-59 196.8 8.0 1.1 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Sulfotransfer_3 PF13469.6 EWM24512.1 - 0.00062 20.2 0.0 0.0012 19.3 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 EWM24512.1 - 0.018 14.6 0.0 0.089 12.2 0.0 1.9 2 0 0 2 2 2 0 Sulfotransferase domain Peptidase_M48 PF01435.18 EWM24513.1 - 2.5e-28 99.2 0.1 6.7e-28 97.8 0.1 1.6 1 1 0 1 1 1 1 Peptidase family M48 Peptidase_M78 PF06114.13 EWM24513.1 - 0.05 13.5 0.1 0.094 12.6 0.0 1.7 2 0 0 2 2 2 0 IrrE N-terminal-like domain DUF4157 PF13699.6 EWM24513.1 - 0.11 12.8 0.2 0.19 12.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4157) DUF2268 PF10026.9 EWM24513.1 - 0.15 11.6 0.1 0.21 11.1 0.1 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) DUF2201_N PF13203.6 EWM24513.1 - 0.23 11.1 1.5 0.64 9.6 0.5 1.8 1 1 1 2 2 2 0 Putative metallopeptidase domain Proteasom_PSMB PF10508.9 EWM24514.1 - 7.1e-12 44.6 0.0 9e-12 44.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit CBM49 PF09478.10 EWM24515.1 - 0.0031 17.8 0.0 0.0079 16.5 0.0 1.6 1 1 0 1 1 1 1 Carbohydrate binding domain CBM49 Exo_endo_phos PF03372.23 EWM24516.1 - 6.9e-05 22.5 0.3 0.00043 19.9 0.3 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UBA PF00627.31 EWM24517.1 - 5e-11 42.3 0.3 8.9e-11 41.5 0.3 1.4 1 0 0 1 1 1 1 UBA/TS-N domain CUE PF02845.16 EWM24517.1 - 0.00067 19.3 0.5 0.0082 15.8 0.1 2.3 2 0 0 2 2 2 1 CUE domain HOIP-UBA PF16678.5 EWM24517.1 - 0.0049 16.9 0.0 0.0085 16.1 0.0 1.3 1 0 0 1 1 1 1 HOIP UBA domain pair UBA_5 PF16577.5 EWM24517.1 - 0.013 15.6 0.2 0.031 14.4 0.0 1.7 2 0 0 2 2 2 0 UBA domain UBA_4 PF14555.6 EWM24517.1 - 0.026 14.3 0.1 0.052 13.4 0.1 1.5 1 0 0 1 1 1 0 UBA-like domain ubiquitin PF00240.23 EWM24518.1 - 9.6e-18 63.7 0.0 1.5e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EWM24518.1 - 1.6e-09 37.4 0.2 2.7e-09 36.7 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 EWM24518.1 - 0.0068 16.4 0.4 1.3 9.2 0.1 2.3 1 1 1 2 2 2 2 Ubiquitin-like domain DUF2407 PF10302.9 EWM24518.1 - 0.022 15.3 0.0 0.048 14.2 0.0 1.6 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain TBK1_ULD PF18396.1 EWM24518.1 - 0.084 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain DUF3460 PF11943.8 EWM24518.1 - 0.21 11.9 0.4 0.21 11.9 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3460) Fur_reg_FbpB PF13040.6 EWM24518.1 - 1.3 8.6 5.7 3.1 7.4 0.5 2.4 2 0 0 2 2 2 0 Fur-regulated basic protein B CAP_N PF01213.19 EWM24518.1 - 2.6 7.4 8.5 27 4.1 0.0 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal GRIP PF01465.20 EWM24519.1 - 1.2e-12 47.5 0.0 2.4e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 GRIP domain MIP-T3_C PF17749.1 EWM24519.1 - 1.1 9.2 13.7 1 9.3 5.0 2.4 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region DUF4472 PF14739.6 EWM24519.1 - 2.3 9.0 20.3 2.3 9.0 13.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) NleF_casp_inhib PF16809.5 EWM24519.1 - 4.1 7.3 6.6 3.1 7.7 0.2 2.3 2 0 0 2 2 2 0 NleF caspase inhibitor VSG_B PF13206.6 EWM24519.1 - 4.4 6.4 8.1 7.1 5.8 8.1 1.4 1 0 0 1 1 1 0 Trypanosomal VSG domain DUF16 PF01519.16 EWM24519.1 - 5.2 7.6 11.7 8.5 6.9 0.6 2.6 2 1 1 3 3 3 0 Protein of unknown function DUF16 PUB PF09409.10 EWM24520.1 - 3.9e-14 52.4 0.0 6.9e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 PUB domain ubiquitin PF00240.23 EWM24520.1 - 5.5e-12 45.3 0.0 8.6e-12 44.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EWM24520.1 - 0.025 14.4 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like SLC35F PF06027.12 EWM24522.1 - 1.1e-73 248.4 4.7 1.5e-41 142.8 0.4 2.1 2 0 0 2 2 2 2 Solute carrier family 35 EamA PF00892.20 EWM24522.1 - 1.8e-10 41.1 16.2 1.2e-06 28.8 1.2 2.7 2 1 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 EWM24522.1 - 9.8e-08 31.3 0.0 1.8e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 EWM24522.1 - 2.3e-05 23.8 0.0 0.00011 21.5 0.0 2.0 1 1 0 1 1 1 1 UAA transporter family HMG_box PF00505.19 EWM24523.1 - 9.7e-17 61.2 1.1 1.7e-16 60.4 1.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EWM24523.1 - 1.3e-12 48.1 0.9 2.5e-12 47.2 0.9 1.5 1 0 0 1 1 1 1 HMG-box domain FA_desaturase PF00487.24 EWM24524.1 - 8.3e-12 45.5 17.0 8.3e-12 45.5 17.0 1.8 1 1 1 2 2 2 2 Fatty acid desaturase DUF3474 PF11960.8 EWM24524.1 - 0.0028 17.9 0.0 0.0047 17.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) FA_desaturase PF00487.24 EWM24525.1 - 0.0064 16.4 0.1 0.007 16.2 0.1 1.0 1 0 0 1 1 1 1 Fatty acid desaturase FA_desaturase PF00487.24 EWM24526.1 - 0.0033 17.3 0.6 0.0041 17.0 0.6 1.1 1 0 0 1 1 1 1 Fatty acid desaturase MCM_OB PF17207.3 EWM24527.1 - 1.8e-33 115.1 0.0 2.7e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 EWM24527.1 - 6.9e-15 55.5 0.0 1.3e-14 54.6 0.0 1.5 1 0 0 1 1 1 1 MCM N-terminal domain MCM PF00493.23 EWM24527.1 - 2.9e-07 29.8 0.0 4.5e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain NAD_binding_8 PF13450.6 EWM24528.1 - 8e-09 35.6 0.2 1.9e-08 34.4 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EWM24528.1 - 2.6e-08 33.6 0.1 0.0021 17.4 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 EWM24528.1 - 1.5e-07 31.3 3.5 1.6e-06 28.0 3.1 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EWM24528.1 - 0.00043 19.6 0.0 0.0018 17.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EWM24528.1 - 0.0026 17.7 0.1 0.0051 16.8 0.1 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding PRMT5 PF05185.16 EWM24528.1 - 0.0031 17.4 0.0 0.005 16.7 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Trp_halogenase PF04820.14 EWM24528.1 - 0.0095 14.8 0.5 0.015 14.2 0.5 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Lycopene_cycl PF05834.12 EWM24528.1 - 0.1 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 EWM24528.1 - 0.18 12.3 0.3 2.1 9.0 0.7 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EWM24528.1 - 0.19 10.7 1.8 0.36 9.9 1.8 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 EWM24529.1 - 8e-09 35.6 0.2 1.9e-08 34.4 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EWM24529.1 - 2.6e-08 33.6 0.1 0.0021 17.4 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 EWM24529.1 - 1.5e-07 31.3 3.5 1.6e-06 28.0 3.1 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EWM24529.1 - 0.00043 19.6 0.0 0.0018 17.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EWM24529.1 - 0.0026 17.7 0.1 0.0051 16.8 0.1 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding PRMT5 PF05185.16 EWM24529.1 - 0.0031 17.4 0.0 0.005 16.7 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Trp_halogenase PF04820.14 EWM24529.1 - 0.0095 14.8 0.5 0.015 14.2 0.5 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Lycopene_cycl PF05834.12 EWM24529.1 - 0.1 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 EWM24529.1 - 0.18 12.3 0.3 2.1 9.0 0.7 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EWM24529.1 - 0.19 10.7 1.8 0.36 9.9 1.8 1.4 1 0 0 1 1 1 0 FAD binding domain SOUL PF04832.12 EWM24530.1 - 1.9e-39 135.5 0.0 2.3e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 SOUL heme-binding protein DUF1743 PF08489.11 EWM24530.1 - 0.12 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1743) Kelch_4 PF13418.6 EWM24531.1 - 1.9e-12 47.0 4.2 1.7e-07 31.1 0.0 5.5 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 EWM24531.1 - 2.4e-10 40.1 4.3 0.0017 18.3 0.0 5.2 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 EWM24531.1 - 4e-10 39.1 1.6 2.2e-06 27.1 0.0 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 EWM24531.1 - 4.1e-10 39.7 10.8 3.5e-05 24.0 0.1 6.0 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.6 EWM24531.1 - 1.5e-05 25.1 0.3 0.0058 16.9 0.0 4.2 5 0 0 5 5 5 1 Kelch motif RRM_1 PF00076.22 EWM24532.1 - 7.2e-25 86.6 0.0 1.5e-07 31.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MCM PF00493.23 EWM24533.1 - 3.6e-34 117.8 0.3 8.4e-34 116.6 0.1 1.6 2 0 0 2 2 2 1 MCM P-loop domain MCM_lid PF17855.1 EWM24533.1 - 6e-28 97.1 0.3 1.2e-27 96.1 0.3 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain AAA_lid_2 PF17863.1 EWM24533.1 - 0.0056 16.5 0.3 0.015 15.1 0.3 1.7 1 0 0 1 1 1 1 AAA lid domain TIP49_C PF17856.1 EWM24533.1 - 0.094 12.9 0.1 0.22 11.7 0.1 1.6 1 0 0 1 1 1 0 TIP49 AAA-lid domain Pou PF00157.17 EWM24533.1 - 0.11 12.4 0.5 4.7 7.2 0.1 2.6 2 0 0 2 2 2 0 Pou domain - N-terminal to homeobox domain COX1 PF00115.20 EWM24534.1 - 0.031 13.1 2.2 0.044 12.6 2.2 1.3 1 0 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I Yip1 PF04893.17 EWM24535.1 - 1.5e-05 24.8 0.1 1.9e-05 24.4 0.1 1.1 1 0 0 1 1 1 1 Yip1 domain DUF3592 PF12158.8 EWM24535.1 - 0.16 12.0 0.4 0.28 11.3 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3592) Lipase_GDSL_2 PF13472.6 EWM24536.1 - 6e-10 39.8 0.0 3.4e-09 37.4 0.0 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EWM24536.1 - 4.8e-06 26.7 0.0 2.4e-05 24.4 0.0 2.1 3 0 0 3 3 3 1 GDSL-like Lipase/Acylhydrolase AAA_9 PF12781.7 EWM24537.1 - 7e-66 221.5 4.4 1.2e-65 220.7 0.0 2.7 3 0 0 3 3 3 1 ATP-binding dynein motor region MT PF12777.7 EWM24537.1 - 3.9e-45 154.4 6.1 6.6e-45 153.6 6.1 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 EWM24537.1 - 2.2e-27 95.9 0.0 4.2e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EWM24537.1 - 6e-26 90.9 0.0 1.7e-25 89.4 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain Dynein_C PF18199.1 EWM24537.1 - 3e-25 89.1 0.0 9.7e-25 87.4 0.0 1.8 1 1 0 1 1 1 1 Dynein heavy chain C-terminal domain CENP-F_leu_zip PF10473.9 EWM24537.1 - 0.0039 17.2 1.0 0.0039 17.2 1.0 3.5 3 0 0 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3446 PF11928.8 EWM24537.1 - 0.36 11.1 1.7 0.46 10.8 0.2 1.9 2 0 0 2 2 2 0 Early growth response N-terminal domain JIP_LZII PF16471.5 EWM24537.1 - 2.7 8.2 10.0 0.39 10.9 0.7 3.5 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II Asp_protease_2 PF13650.6 EWM24538.1 - 2.7e-13 50.3 0.3 1.7e-06 28.5 0.1 2.6 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 EWM24538.1 - 1e-09 38.8 0.0 6.3e-06 26.7 0.0 2.7 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 EWM24538.1 - 0.0025 17.6 0.0 0.81 9.5 0.0 2.2 2 0 0 2 2 2 2 Aspartyl protease SAP PF02037.27 EWM24538.1 - 0.0028 17.4 0.1 0.0045 16.7 0.1 1.3 1 0 0 1 1 1 1 SAP domain RVP PF00077.20 EWM24538.1 - 0.054 13.8 0.0 0.29 11.5 0.0 2.0 2 0 0 2 2 2 0 Retroviral aspartyl protease AAA_6 PF12774.7 EWM24539.1 - 1.2e-102 343.3 0.0 2.7e-102 342.1 0.0 1.5 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region AAA_5 PF07728.14 EWM24539.1 - 0.00029 20.8 0.0 0.047 13.7 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EWM24539.1 - 0.052 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.25 EWM24540.1 - 5.9e-51 173.4 0.0 6.7e-47 160.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EWM24540.1 - 1.1e-30 106.8 0.0 2.6e-29 102.3 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EWM24540.1 - 0.00073 18.9 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EWM24540.1 - 0.035 12.9 0.0 0.055 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EWM24540.1 - 0.052 13.5 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family CLP_protease PF00574.23 EWM24541.1 - 7.5e-50 169.3 0.0 1.2e-49 168.7 0.0 1.3 1 0 0 1 1 1 1 Clp protease Pkinase PF00069.25 EWM24542.1 - 5.4e-56 189.9 0.0 6.4e-56 189.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM24542.1 - 2.6e-36 125.3 0.0 3.5e-36 124.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EWM24542.1 - 2e-05 23.6 0.0 3e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EWM24542.1 - 4.9e-05 22.8 0.0 6.3e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EWM24542.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Docking PF08990.11 EWM24543.1 - 0.091 12.4 0.2 0.23 11.1 0.2 1.7 1 0 0 1 1 1 0 Erythronolide synthase docking Snf7 PF03357.21 EWM24544.1 - 3.5e-41 140.7 5.8 3.5e-41 140.7 5.8 1.7 2 0 0 2 2 2 1 Snf7 DUF948 PF06103.11 EWM24544.1 - 0.56 10.5 2.2 23 5.3 0.1 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TBPIP PF07106.13 EWM24545.1 - 7.1e-22 77.1 0.2 2.6e-21 75.3 0.0 2.0 2 0 0 2 2 2 1 TBPIP/Hop2 winged helix domain Penicillinase_R PF03965.16 EWM24545.1 - 0.00022 21.5 0.0 0.0011 19.3 0.0 2.1 2 0 0 2 2 2 1 Penicillinase repressor FUR PF01475.19 EWM24545.1 - 0.035 14.3 0.0 0.06 13.5 0.0 1.4 1 0 0 1 1 1 0 Ferric uptake regulator family TrmB PF01978.19 EWM24545.1 - 0.079 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_41 PF14502.6 EWM24545.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain BSP_II PF05432.11 EWM24545.1 - 0.15 11.7 29.5 0.25 11.0 29.5 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CAC1F_C PF16885.5 EWM24545.1 - 0.29 10.7 14.2 0.49 10.0 14.2 1.4 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term HCR PF07111.12 EWM24546.1 - 0.011 13.9 3.0 0.021 12.9 3.0 1.5 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) 3-PAP PF12578.8 EWM24546.1 - 0.14 11.9 0.0 3.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Myotubularin-associated protein SlyX PF04102.12 EWM24546.1 - 0.7 10.5 9.7 16 6.2 0.2 3.6 2 2 1 3 3 3 0 SlyX PX PF00787.24 EWM24547.1 - 4.6e-15 55.6 0.0 7.8e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 PX domain FAIM1 PF06905.13 EWM24547.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Fas apoptotic inhibitory molecule (FAIM1) DUF1823 PF08853.11 EWM24548.1 - 8.1e-39 132.3 0.3 1.2e-38 131.7 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1823) DUF2716 PF10898.8 EWM24548.1 - 0.025 15.0 0.0 0.042 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2716) His_Phos_2 PF00328.22 EWM24549.1 - 2.9e-12 46.6 0.0 1.1e-11 44.8 0.0 1.8 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 2) BUD22 PF09073.10 EWM24550.1 - 0.052 12.9 16.5 0.07 12.5 16.5 1.2 1 0 0 1 1 1 0 BUD22 FAM176 PF14851.6 EWM24550.1 - 0.097 12.3 17.3 0.44 10.2 0.9 2.2 2 0 0 2 2 2 0 FAM176 family SDA1 PF05285.12 EWM24550.1 - 1.4 8.3 24.0 2 7.8 24.0 1.2 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 EWM24550.1 - 2.8 6.6 8.5 3.7 6.2 8.5 1.1 1 0 0 1 1 1 0 Presenilin Polyoma_coat2 PF00761.20 EWM24550.1 - 3.4 7.3 4.5 4.4 6.9 4.5 1.1 1 0 0 1 1 1 0 Polyomavirus coat protein CENP-B_dimeris PF09026.10 EWM24550.1 - 5.6 7.4 19.6 0.26 11.7 1.7 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 EWM24550.1 - 7.4 7.0 31.7 2 8.8 18.8 2.3 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NmrA PF05368.13 EWM24553.1 - 1.4e-22 80.4 0.0 1.9e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EWM24553.1 - 3.3e-19 69.5 0.0 5.3e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EWM24553.1 - 1.3e-09 37.8 0.0 2.1e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EWM24553.1 - 1.2e-05 25.6 0.1 1.9e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 EWM24553.1 - 0.0051 16.2 0.0 0.007 15.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 EWM24553.1 - 0.062 12.8 0.4 0.11 12.0 0.1 1.5 2 0 0 2 2 2 0 short chain dehydrogenase 3Beta_HSD PF01073.19 EWM24553.1 - 0.086 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family WD40 PF00400.32 EWM24554.1 - 4.2e-14 52.7 12.9 0.0015 19.3 0.1 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM24554.1 - 0.00066 19.9 0.0 1 9.7 0.0 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EWM24554.1 - 0.0013 17.8 0.1 0.013 14.4 0.0 2.2 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EWM24554.1 - 0.06 12.7 0.0 0.12 11.6 0.0 1.4 2 0 0 2 2 2 0 WD40-like domain PD40 PF07676.12 EWM24554.1 - 0.15 12.0 0.7 6.8 6.8 0.2 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Abhydrolase_6 PF12697.7 EWM24555.1 - 7.5e-12 46.3 2.6 1.3e-11 45.5 2.6 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family HCV_NS4b PF01001.19 EWM24555.1 - 0.017 14.7 0.6 0.033 13.8 0.6 1.5 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4b Lipase_3 PF01764.25 EWM24555.1 - 0.019 14.8 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.16 EWM24555.1 - 0.18 11.6 0.1 5.5 6.7 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DDOST_48kD PF03345.14 EWM24556.1 - 7e-118 394.0 0.0 8.7e-118 393.7 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF4350 PF14258.6 EWM24556.1 - 0.086 13.3 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) Presenilin PF01080.17 EWM24557.1 - 0.75 8.5 6.9 1.2 7.8 6.9 1.3 1 0 0 1 1 1 0 Presenilin E1-E2_ATPase PF00122.20 EWM24559.1 - 1.2e-14 54.2 2.0 8.3e-11 41.7 0.3 2.6 2 0 0 2 2 2 2 E1-E2 ATPase Hydrolase PF00702.26 EWM24559.1 - 2.4e-14 54.1 14.8 8e-06 26.3 0.1 4.0 4 0 0 4 4 4 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EWM24559.1 - 0.0091 16.1 0.0 0.031 14.3 0.0 1.9 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EWM24559.1 - 0.013 15.2 0.3 0.2 11.4 0.1 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Barttin PF15462.6 EWM24559.1 - 0.033 14.0 6.2 0.12 12.1 0.6 2.4 2 0 0 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) SNF2_N PF00176.23 EWM24560.1 - 2.3e-53 181.2 0.7 3.7e-53 180.5 0.7 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain PHD PF00628.29 EWM24560.1 - 1.6e-31 108.0 86.0 4e-08 33.0 4.7 7.5 8 0 0 8 8 8 6 PHD-finger Helicase_C PF00271.31 EWM24560.1 - 1.2e-22 80.3 0.0 2.4e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 EWM24560.1 - 1.1e-15 57.4 0.0 2.9e-15 56.1 0.0 1.7 1 0 0 1 1 1 1 Bromodomain Chromo PF00385.24 EWM24560.1 - 2.3e-11 43.4 4.2 2.1e-08 33.9 0.5 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain PHD_2 PF13831.6 EWM24560.1 - 1.3e-09 37.5 31.0 0.00013 21.4 2.2 5.4 5 0 0 5 5 5 4 PHD-finger ResIII PF04851.15 EWM24560.1 - 2.5e-08 34.1 0.0 5.2e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EWM24560.1 - 2e-05 24.5 0.0 9.8e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-C2H2_jaz PF12171.8 EWM24560.1 - 0.0033 17.7 1.4 1.8 9.0 0.3 3.8 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding HDA2-3 PF11496.8 EWM24560.1 - 0.0039 16.4 0.0 0.012 14.8 0.0 1.8 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 zf-ribbon_3 PF13248.6 EWM24560.1 - 0.028 13.8 6.7 0.01 15.2 2.6 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf_C2H2_6 PF18450.1 EWM24560.1 - 0.1 12.3 0.3 0.45 10.3 0.1 2.2 2 0 0 2 2 2 0 Zinc Finger domain DUF1738 PF08401.11 EWM24560.1 - 0.19 11.8 0.5 0.65 10.1 0.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1738) S10_plectin PF03501.15 EWM24561.1 - 1.8e-34 117.7 0.4 2.7e-34 117.1 0.4 1.3 1 0 0 1 1 1 1 Plectin/S10 domain Sterol_MT_C PF08498.10 EWM24562.1 - 7.4e-25 87.0 0.1 1.4e-24 86.2 0.1 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 EWM24562.1 - 2.4e-18 66.5 0.0 6.5e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EWM24562.1 - 5e-17 62.1 0.0 8.5e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 EWM24562.1 - 6.1e-17 62.1 0.0 2.1e-16 60.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM24562.1 - 3.8e-15 56.0 0.0 6.5e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EWM24562.1 - 8.6e-13 48.5 0.0 1.5e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EWM24562.1 - 4e-08 32.9 0.0 7e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EWM24562.1 - 1.5e-07 32.1 0.0 3e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EWM24562.1 - 0.059 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 EWM24562.1 - 0.063 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW GTP_EFTU PF00009.27 EWM24563.1 - 6.2e-46 156.4 0.0 1.1e-45 155.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EWM24563.1 - 2.2e-26 92.3 0.0 8.8e-26 90.4 0.0 2.1 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EWM24563.1 - 2.3e-13 50.3 1.4 5.6e-13 49.1 1.4 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EWM24563.1 - 0.00063 19.8 0.0 0.0033 17.5 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase PAM2 PF07145.15 EWM24563.1 - 0.0021 17.6 2.8 0.016 14.9 0.9 2.5 1 1 1 2 2 2 2 Ataxin-2 C-terminal region 2CSK_N PF08521.10 EWM24564.1 - 0.018 15.1 0.4 0.037 14.1 0.4 1.5 1 0 0 1 1 1 0 Two-component sensor kinase N-terminal MgtE PF01769.16 EWM24565.1 - 0.1 13.0 0.9 0.16 12.4 0.9 1.3 1 0 0 1 1 1 0 Divalent cation transporter Nop PF01798.18 EWM24566.1 - 6.1e-86 287.6 0.1 6.1e-86 287.6 0.1 1.6 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin DUF4604 PF15377.6 EWM24566.1 - 0.2 12.1 23.7 0.28 11.6 23.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Presenilin PF01080.17 EWM24566.1 - 1.3 7.8 7.6 1.3 7.7 6.1 1.8 2 0 0 2 2 2 0 Presenilin RNA_pol_Rpc4 PF05132.14 EWM24566.1 - 8.3 6.8 12.1 14 6.1 12.1 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 HGTP_anticodon PF03129.20 EWM24567.1 - 1.5e-18 66.7 0.0 2.9e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EWM24567.1 - 8.3e-10 38.9 0.0 1.6e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF1820 PF08850.11 EWM24567.1 - 0.027 14.9 0.0 0.054 14.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1820) Proteasome_A_N PF10584.9 EWM24567.1 - 0.58 9.9 1.5 0.9 9.3 0.1 1.9 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature NOP5NT PF08156.13 EWM24568.1 - 4.8e-22 78.1 0.2 7.7e-22 77.5 0.2 1.3 1 0 0 1 1 1 1 NOP5NT (NUC127) domain RL PF17797.1 EWM24568.1 - 0.029 14.3 0.1 0.053 13.5 0.1 1.4 1 0 0 1 1 1 0 RL domain DUF5334 PF17268.2 EWM24568.1 - 0.16 12.3 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5334) LysM PF01476.20 EWM24569.1 - 0.00023 21.2 0.0 0.00039 20.4 0.0 1.3 1 0 0 1 1 1 1 LysM domain PDZ_6 PF17820.1 EWM24569.1 - 0.0035 17.2 0.0 0.0077 16.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EWM24569.1 - 0.027 14.8 0.7 0.11 12.8 0.1 2.3 2 1 0 2 2 2 0 PDZ domain zf-RING_2 PF13639.6 EWM24570.1 - 1.5e-12 47.7 4.7 1.5e-12 47.7 4.7 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 EWM24570.1 - 2.1e-09 37.0 1.7 5.1e-09 35.7 1.7 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 EWM24570.1 - 6.4e-09 36.0 2.5 1.6e-08 34.7 2.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EWM24570.1 - 1.6e-08 34.4 2.2 1.6e-08 34.4 2.2 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EWM24570.1 - 9.3e-08 31.8 4.2 9.3e-08 31.8 4.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EWM24570.1 - 5.9e-07 29.3 3.6 5.9e-07 29.3 3.6 2.9 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EWM24570.1 - 1.2e-06 28.2 2.5 1.2e-06 28.2 2.5 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EWM24570.1 - 1e-05 25.3 3.6 2.6e-05 24.0 3.6 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EWM24570.1 - 1.5e-05 24.9 4.6 5.3e-05 23.2 1.3 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EWM24570.1 - 0.00036 20.5 0.5 0.00078 19.4 0.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3H2C3 PF17122.5 EWM24570.1 - 0.045 13.8 3.3 0.17 12.0 2.0 2.3 2 0 0 2 2 2 0 Zinc-finger FANCL_C PF11793.8 EWM24570.1 - 0.08 13.1 4.5 0.26 11.5 4.5 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 EWM24570.1 - 0.22 11.6 4.7 0.65 10.2 4.6 1.8 1 1 0 1 1 1 0 RING-variant domain zf-RING_11 PF17123.5 EWM24571.1 - 8.7e-08 31.8 0.4 2.1e-07 30.5 0.4 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 EWM24571.1 - 3e-06 27.5 14.6 0.00056 20.2 0.3 3.4 3 0 0 3 3 3 2 Ring finger domain zf-rbx1 PF12678.7 EWM24571.1 - 0.0015 18.8 4.8 0.012 15.9 1.0 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EWM24571.1 - 0.0054 16.7 0.0 0.0054 16.7 0.0 2.7 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EWM24571.1 - 0.02 14.7 10.7 0.63 9.9 0.7 3.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EWM24571.1 - 0.039 13.8 4.2 1.9 8.4 0.3 2.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EWM24571.1 - 0.15 11.9 17.0 0.21 11.5 0.3 3.7 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EWM24571.1 - 0.44 10.6 6.2 0.76 9.8 0.3 3.4 3 0 0 3 3 3 0 RING-type zinc-finger zf-C3HC4 PF00097.25 EWM24571.1 - 0.84 9.6 15.4 0.58 10.1 0.2 3.9 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) ATP-sulfurylase PF01747.17 EWM24572.1 - 5.9e-69 231.8 0.0 8.1e-69 231.3 0.0 1.1 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 EWM24572.1 - 4.6e-44 149.9 0.0 6.5e-44 149.4 0.0 1.2 1 0 0 1 1 1 1 PUA-like domain Med6 PF04934.14 EWM24573.1 - 1.3e-31 109.1 0.0 1.9e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component Med6 PF04934.14 EWM24574.1 - 1.3e-31 109.1 0.0 1.9e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component dCMP_cyt_deam_1 PF00383.23 EWM24575.1 - 7.7e-17 61.0 0.1 1.2e-14 54.0 0.1 2.1 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EWM24575.1 - 8.2e-12 45.0 0.1 1.3e-10 41.1 0.1 2.1 1 1 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 EWM24575.1 - 0.0034 17.5 0.0 0.006 16.7 0.0 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 EWM24575.1 - 0.0086 16.1 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 1 APOBEC2 APOBEC3 PF18771.1 EWM24575.1 - 0.012 15.8 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 APOBEC3 NAD1 PF18778.1 EWM24575.1 - 0.015 15.4 0.0 0.023 14.8 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 XOO_2897-deam PF14440.6 EWM24575.1 - 0.023 14.8 0.1 0.041 14.0 0.1 1.4 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase APOBEC_N PF08210.11 EWM24575.1 - 0.032 14.1 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 APOBEC-like N-terminal domain APOBEC4_like PF18774.1 EWM24575.1 - 0.059 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase APOBEC1 PF18769.1 EWM24575.1 - 0.11 12.8 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 APOBEC1 NAD2 PF18782.1 EWM24575.1 - 0.14 12.3 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 Bd3614-deam PF14439.6 EWM24575.1 - 0.87 9.7 4.2 8.9 6.4 4.2 2.1 1 1 0 1 1 1 0 Bd3614-like deaminase Nucleotid_trans PF03407.16 EWM24576.1 - 2.6e-28 99.5 0.0 3.6e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase BCAS2 PF05700.11 EWM24577.1 - 3.8e-52 177.0 1.4 4.5e-52 176.7 1.4 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) DUF1664 PF07889.12 EWM24577.1 - 0.12 12.4 1.2 0.55 10.3 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF1192 PF06698.11 EWM24577.1 - 0.12 12.5 0.5 0.12 12.5 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) DNA_topoisoIV PF00521.20 EWM24577.1 - 0.3 9.9 3.9 0.4 9.5 3.9 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Sybindin PF04099.12 EWM24578.1 - 2.6e-43 147.4 0.0 3.2e-43 147.1 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EWM24578.1 - 1.4e-06 28.5 0.0 1.8e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region tRNA-synt_2b PF00587.25 EWM24579.1 - 1.3e-27 97.0 0.0 3.1e-27 95.7 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_SAD PF07973.14 EWM24579.1 - 3.9e-13 49.3 0.0 9.1e-13 48.1 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain MciZ PF13072.6 EWM24579.1 - 0.077 12.8 0.3 0.2 11.5 0.3 1.6 1 0 0 1 1 1 0 Mother cell inhibitor of FtsZ Ribosomal_S5 PF00333.20 EWM24580.1 - 2.6e-29 101.0 0.6 2.6e-29 101.0 0.6 2.1 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EWM24580.1 - 4.5e-25 86.9 0.0 7.7e-25 86.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 EWM24580.1 - 4.3 8.0 14.8 8 7.1 14.8 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Apo-CIII PF05778.12 EWM24581.1 - 0.13 12.0 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) Syntaxin PF00804.25 EWM24582.1 - 0.0023 17.7 0.7 0.0034 17.1 0.7 1.3 1 0 0 1 1 1 1 Syntaxin HTH_40 PF14493.6 EWM24582.1 - 0.065 13.7 0.1 0.072 13.6 0.1 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Methyltransf_31 PF13847.6 EWM24583.1 - 1.5e-13 50.8 0.0 6.5e-13 48.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM24583.1 - 2.5e-12 47.3 0.0 4.9e-11 43.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM24583.1 - 1e-10 42.1 0.0 2.2e-10 41.0 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EWM24583.1 - 1.5e-10 41.7 0.0 2.9e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EWM24583.1 - 4.3e-08 33.2 0.0 6e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EWM24583.1 - 3e-07 30.0 0.0 6.8e-07 28.9 0.0 1.6 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EWM24583.1 - 0.00042 20.1 0.0 0.00064 19.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EWM24583.1 - 0.0011 18.6 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 EWM24583.1 - 0.0021 18.2 0.0 0.0028 17.8 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_9 PF08003.11 EWM24583.1 - 0.0056 15.7 0.0 0.0073 15.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_16 PF10294.9 EWM24583.1 - 0.012 15.4 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Fibrillarin PF01269.17 EWM24583.1 - 0.012 14.7 0.0 0.04 13.0 0.0 1.7 2 0 0 2 2 2 0 Fibrillarin RrnaAD PF00398.20 EWM24583.1 - 0.013 14.6 0.0 0.018 14.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_24 PF13578.6 EWM24583.1 - 0.022 15.8 0.0 0.04 14.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.10 EWM24583.1 - 0.026 14.2 0.0 0.033 13.9 0.0 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_4 PF02390.17 EWM24583.1 - 0.033 13.6 0.0 0.052 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.18 EWM24583.1 - 0.035 13.4 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_32 PF13679.6 EWM24583.1 - 0.11 12.5 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 EWM24583.1 - 0.11 11.8 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.6 EWM24584.1 - 3.2e-13 49.8 0.0 1.9e-12 47.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM24584.1 - 1e-12 48.6 0.0 2.8e-11 44.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM24584.1 - 6.1e-11 42.8 0.0 1.2e-10 41.8 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EWM24584.1 - 8.2e-11 42.5 0.0 1.6e-10 41.6 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EWM24584.1 - 3.4e-08 33.5 0.0 4.9e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EWM24584.1 - 1.4e-07 31.1 0.0 3.4e-07 29.9 0.0 1.5 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EWM24584.1 - 0.00026 20.8 0.0 0.00038 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EWM24584.1 - 0.00075 19.1 0.0 0.00088 18.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 EWM24584.1 - 0.0011 19.1 0.0 0.0014 18.8 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_9 PF08003.11 EWM24584.1 - 0.0032 16.4 0.0 0.004 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_16 PF10294.9 EWM24584.1 - 0.0071 16.1 0.0 0.0098 15.6 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase RrnaAD PF00398.20 EWM24584.1 - 0.0083 15.2 0.0 0.01 14.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_24 PF13578.6 EWM24584.1 - 0.013 16.5 0.0 0.022 15.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.10 EWM24584.1 - 0.016 14.9 0.0 0.019 14.7 0.0 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Fibrillarin PF01269.17 EWM24584.1 - 0.019 14.1 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin Methyltransf_4 PF02390.17 EWM24584.1 - 0.022 14.2 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.18 EWM24584.1 - 0.023 14.0 0.0 0.028 13.7 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase domain GidB PF02527.15 EWM24584.1 - 0.065 12.5 0.0 0.08 12.2 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_32 PF13679.6 EWM24584.1 - 0.068 13.2 0.0 0.12 12.4 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 EWM24584.1 - 0.11 12.3 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Met-10+ like-protein DNA_topoisoIV PF00521.20 EWM24585.1 - 8.5e-124 413.7 0.0 1.2e-123 413.2 0.0 1.2 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 EWM24585.1 - 3.6e-51 172.8 1.1 7e-51 171.8 1.1 1.5 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 EWM24585.1 - 1.6e-24 86.3 0.4 3.4e-24 85.2 0.4 1.5 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 EWM24585.1 - 2.3e-14 53.8 0.1 6.3e-14 52.4 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EWM24585.1 - 3.9e-07 30.2 0.0 1.5e-06 28.3 0.0 2.0 1 0 0 1 1 1 1 Toprim domain JAB PF01398.21 EWM24586.1 - 6.2e-20 71.3 0.0 1e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EWM24586.1 - 6.4e-15 55.5 0.0 1.1e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function E1-E2_ATPase PF00122.20 EWM24587.1 - 1.2e-50 171.6 0.0 1.1e-49 168.4 0.0 2.6 2 1 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EWM24587.1 - 2.4e-44 151.2 0.2 5.2e-44 150.1 0.2 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EWM24587.1 - 6.8e-22 78.8 1.0 8.7e-18 65.4 0.1 2.7 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EWM24587.1 - 5.4e-15 54.8 0.3 3.1e-14 52.4 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EWM24587.1 - 7.9e-12 45.1 0.0 8.5e-11 41.8 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EWM24587.1 - 0.00012 21.9 2.1 0.00024 20.9 2.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EWM24587.1 - 0.018 15.4 0.0 0.046 14.1 0.0 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Ribosomal_60s PF00428.19 EWM24587.1 - 0.099 13.2 5.7 0.41 11.3 5.7 2.0 1 0 0 1 1 1 0 60s Acidic ribosomal protein Transketolase_N PF00456.21 EWM24588.1 - 7.1e-146 485.4 0.1 8.9e-146 485.1 0.1 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EWM24588.1 - 4.3e-43 147.0 0.0 8e-43 146.2 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EWM24588.1 - 7.5e-08 32.3 0.0 1.8e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 EWM24588.1 - 0.00091 18.5 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Inositol_P PF00459.25 EWM24589.1 - 1e-57 195.8 0.1 1.3e-57 195.5 0.1 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family Dcc1 PF09724.9 EWM24590.1 - 3.6e-47 161.3 0.0 1.2e-46 159.5 0.0 1.8 1 1 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 HisKA PF00512.25 EWM24591.1 - 0.15 12.1 0.4 0.94 9.6 0.1 2.3 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain bZIP_1 PF00170.21 EWM24592.1 - 3.5e-12 46.2 7.2 3.5e-12 46.2 7.2 1.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 EWM24592.1 - 1.5e-06 28.2 10.7 1.5e-06 28.2 10.7 1.9 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 EWM24592.1 - 0.0013 19.2 4.0 0.0013 19.2 4.0 2.0 2 0 0 2 2 2 1 bZIP Maf transcription factor XRCC4 PF06632.12 EWM24592.1 - 0.0062 15.4 4.0 0.0062 15.4 4.0 2.0 2 0 0 2 2 2 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 SR-25 PF10500.9 EWM24592.1 - 0.1 12.2 31.1 0.21 11.2 6.2 2.9 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein IQCJ-SCHIP1 PF15157.6 EWM24592.1 - 0.26 11.1 6.5 0.095 12.5 1.8 2.2 2 0 0 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Autotransporter PF03797.19 EWM24593.1 - 0.07 12.8 0.2 0.11 12.2 0.2 1.3 1 0 0 1 1 1 0 Autotransporter beta-domain Cyclin PF08613.11 EWM24594.1 - 7.7e-36 123.9 0.2 1.4e-35 123.0 0.2 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EWM24594.1 - 3.4e-10 39.8 0.1 6.7e-10 38.8 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain CDC37_M PF08565.11 EWM24595.1 - 2e-20 72.9 0.8 2e-20 72.9 0.8 2.0 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_N PF03234.14 EWM24595.1 - 9.2e-16 58.9 9.3 9.2e-16 58.9 9.3 2.3 2 1 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_C PF08564.10 EWM24595.1 - 1.5e-11 44.3 0.0 1.5e-11 44.3 0.0 2.9 2 1 1 3 3 3 1 Cdc37 C terminal domain SPARC_Ca_bdg PF10591.9 EWM24595.1 - 0.024 15.0 5.5 0.1 12.9 4.6 2.3 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region MCD_N PF17408.2 EWM24595.1 - 0.32 11.1 3.2 1.2 9.3 3.2 2.0 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase N-terminal domain Fer4_13 PF13370.6 EWM24596.1 - 1.1e-06 29.0 0.1 3.5e-06 27.4 0.1 1.9 1 1 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Lactamase_B_5 PF14597.6 EWM24596.1 - 8.5e-05 22.1 0.0 0.00038 20.0 0.0 2.0 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B PF00753.27 EWM24596.1 - 0.00018 21.6 0.0 0.0004 20.4 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Fer4_15 PF13459.6 EWM24596.1 - 0.0015 19.3 0.1 0.0034 18.1 0.1 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain PLD_C PF12357.8 EWM24596.1 - 0.097 12.6 0.0 17 5.4 0.0 2.5 2 0 0 2 2 2 0 Phospholipase D C terminal FYVE PF01363.21 EWM24597.1 - 4.1e-09 36.4 13.0 8.9e-09 35.4 13.0 1.5 1 0 0 1 1 1 1 FYVE zinc finger DUF4746 PF15928.5 EWM24597.1 - 0.0061 16.0 1.3 0.0092 15.4 1.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4746) RhoGEF67_u1 PF16615.5 EWM24597.1 - 0.13 12.8 12.9 0.41 11.2 12.9 1.9 1 0 0 1 1 1 0 Unstructured region one on RhoGEF 6 and 7 RNA_pol_3_Rpc31 PF11705.8 EWM24597.1 - 0.17 12.1 8.6 0.33 11.2 8.6 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Pox_Ag35 PF03286.14 EWM24597.1 - 0.34 10.7 2.4 0.52 10.1 2.4 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PPP4R2 PF09184.11 EWM24597.1 - 0.45 10.0 5.4 0.81 9.2 5.4 1.4 1 0 0 1 1 1 0 PPP4R2 Radial_spoke PF04712.12 EWM24597.1 - 6 5.7 11.6 8.5 5.2 11.6 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein ERCC4 PF02732.15 EWM24598.1 - 1.1e-16 61.5 0.0 1.8e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain RPA_interact_N PF14766.6 EWM24599.1 - 3.9e-06 26.4 0.1 7.3e-06 25.5 0.1 1.4 1 0 0 1 1 1 1 Replication protein A interacting N-terminal RPA_interact_C PF14768.6 EWM24599.1 - 0.0021 18.6 0.8 0.006 17.1 0.8 1.8 1 0 0 1 1 1 1 Replication protein A interacting C-terminal Methyltransf_11 PF08241.12 EWM24600.1 - 2.7e-19 69.6 0.0 7.7e-19 68.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM24600.1 - 4.1e-18 65.9 0.0 7.8e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EWM24600.1 - 8.8e-15 54.7 0.0 6.1e-14 51.9 0.0 2.2 2 1 1 3 3 3 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EWM24600.1 - 1.4e-12 48.2 0.0 2.4e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM24600.1 - 1.6e-10 41.0 0.0 2.5e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EWM24600.1 - 2.3e-08 34.0 0.0 5.1e-08 32.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EWM24600.1 - 0.00055 19.9 0.0 0.0075 16.1 0.0 2.2 1 1 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 EWM24600.1 - 0.015 14.9 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.19 EWM24600.1 - 0.051 13.3 0.0 0.078 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 EWM24600.1 - 0.2 11.6 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain AviRa PF11599.8 EWM24600.1 - 0.2 11.1 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 RRNA methyltransferase AviRa HLH PF00010.26 EWM24601.1 - 7.3e-06 25.8 0.0 1.9e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF1948 PF09185.10 EWM24601.1 - 0.11 12.4 0.9 0.17 11.7 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1948) FUSC PF04632.12 EWM24601.1 - 0.2 10.2 4.5 0.27 9.7 4.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family SKIP_SNW PF02731.15 EWM24601.1 - 0.67 9.6 6.4 0.63 9.7 5.0 1.5 1 1 0 1 1 1 0 SKIP/SNW domain NAM-associated PF14303.6 EWM24601.1 - 3.8 8.2 10.5 6.4 7.5 10.5 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain SAE2 PF08573.10 EWM24601.1 - 7.1 7.8 9.0 5.5 8.2 3.4 2.3 1 1 1 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus JAB PF01398.21 EWM24603.1 - 7.3e-14 51.8 0.0 1.2e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 EWM24603.1 - 1.5e-10 41.2 0.2 2.6e-10 40.5 0.2 1.2 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 EWM24603.1 - 7.9e-05 22.4 0.0 0.00017 21.4 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain O-FucT PF10250.9 EWM24604.1 - 1.6e-06 28.1 1.4 3.8e-05 23.5 1.4 2.9 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase BolA PF01722.18 EWM24605.1 - 9.6e-29 99.5 1.1 1.3e-28 99.1 1.1 1.2 1 0 0 1 1 1 1 BolA-like protein Lipase_3 PF01764.25 EWM24606.1 - 1.1e-18 67.4 0.0 1.9e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) FYVE PF01363.21 EWM24606.1 - 7.6e-12 45.2 10.3 1.5e-11 44.2 10.3 1.5 1 0 0 1 1 1 1 FYVE zinc finger Abhydrolase_3 PF07859.13 EWM24606.1 - 0.024 14.5 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 EWM24606.1 - 0.1 12.7 0.6 0.25 11.4 0.6 1.6 1 0 0 1 1 1 0 Thioesterase domain Tudor_3 PF18115.1 EWM24606.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain zf-AN1 PF01428.16 EWM24606.1 - 1.5 9.0 12.4 4.5 7.5 12.4 1.8 1 0 0 1 1 1 0 AN1-like Zinc finger DiS_P_DiS PF06750.13 EWM24606.1 - 4.8 7.4 5.5 23 5.2 5.5 2.0 1 1 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain ABC2_membrane PF01061.24 EWM24607.1 - 1e-27 96.9 23.1 1.6e-27 96.3 23.1 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EWM24607.1 - 4.4e-24 85.6 0.0 7.2e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EWM24607.1 - 1.2e-05 25.3 0.7 0.043 13.6 0.1 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EWM24607.1 - 0.00056 20.3 0.0 0.00094 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain ABC2_membrane_3 PF12698.7 EWM24607.1 - 0.0013 17.9 24.0 0.0013 17.9 24.0 2.1 1 1 1 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 EWM24607.1 - 0.0056 16.6 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 EWM24607.1 - 0.01 15.5 0.1 0.024 14.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EWM24607.1 - 0.028 14.7 0.0 0.11 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 EWM24607.1 - 0.035 13.6 0.0 0.21 11.0 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EWM24607.1 - 0.071 13.6 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EWM24607.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Cpn60_TCP1 PF00118.24 EWM24608.1 - 2.2e-92 310.3 18.7 4.2e-92 309.3 18.7 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.24 EWM24609.1 - 2.1e-92 310.3 18.7 4.1e-92 309.4 18.7 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DNA_gyraseB PF00204.25 EWM24610.1 - 1.4e-52 177.7 0.0 2.1e-52 177.1 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase B DNA_gyraseB_C PF00986.21 EWM24610.1 - 3.6e-28 97.5 0.8 4e-27 94.2 0.2 2.5 2 0 0 2 2 2 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.26 EWM24610.1 - 1.6e-19 70.4 0.1 3.3e-19 69.5 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EWM24610.1 - 8.6e-18 64.5 0.0 2.8e-17 62.8 0.0 1.8 2 0 0 2 2 2 1 Toprim domain HATPase_c_3 PF13589.6 EWM24610.1 - 0.0028 17.5 0.0 0.0057 16.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Abhydrolase_1 PF00561.20 EWM24611.1 - 3.8e-08 33.3 0.0 1e-06 28.6 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 EWM24611.1 - 8.5e-08 32.2 0.1 0.00025 20.9 0.1 2.4 2 0 0 2 2 2 2 PGAP1-like protein Hydrolase_4 PF12146.8 EWM24611.1 - 1.5e-07 31.0 0.0 0.00026 20.3 0.1 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EWM24611.1 - 4.2e-05 24.3 0.4 8.7e-05 23.2 0.4 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 EWM24611.1 - 0.00015 21.6 0.0 0.00029 20.6 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 EWM24611.1 - 0.00022 20.7 0.0 0.067 12.5 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) DLH PF01738.18 EWM24611.1 - 0.021 14.4 0.0 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family LCAT PF02450.15 EWM24611.1 - 0.046 12.9 0.0 0.071 12.3 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Palm_thioest PF02089.15 EWM24611.1 - 0.15 11.9 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase UDPG_MGDP_dh_N PF03721.14 EWM24612.1 - 9.8e-56 188.3 0.3 1.6e-55 187.6 0.3 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 EWM24612.1 - 5.1e-33 113.6 0.1 3.4e-32 111.0 0.0 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 EWM24612.1 - 7.3e-32 109.4 0.0 1.5e-31 108.5 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain Sacchrp_dh_NADP PF03435.18 EWM24612.1 - 0.11 12.8 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Peptidase_C13 PF01650.18 EWM24613.1 - 4.6e-42 144.3 0.0 6.7e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family DUF5596 PF18082.1 EWM24613.1 - 0.029 14.2 0.0 7.3 6.5 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF5596) Peptidase_C13 PF01650.18 EWM24614.1 - 6.6e-30 104.5 0.0 9.3e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family SecY PF00344.20 EWM24615.1 - 3.4e-72 243.3 11.4 4.5e-72 242.9 11.4 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 EWM24615.1 - 8.8e-19 67.1 0.1 2.7e-18 65.5 0.1 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p DEAD PF00270.29 EWM24618.1 - 6.9e-47 159.5 0.0 1.6e-46 158.3 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EWM24618.1 - 1e-20 74.1 0.0 4.4e-20 72.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 EWM24618.1 - 3.1e-13 49.8 2.5 3.1e-13 49.8 2.5 2.4 2 0 0 2 2 2 1 DBP10CT (NUC160) domain ResIII PF04851.15 EWM24618.1 - 1.4e-05 25.1 0.0 2.9e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit MFS_1 PF07690.16 EWM24619.1 - 3.7e-26 91.9 25.9 3.7e-26 91.9 25.9 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 EWM24619.1 - 9.2e-26 90.2 17.9 1.1e-16 60.3 0.1 3.3 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 EWM24619.1 - 5.1e-08 32.2 6.6 5.1e-08 32.2 6.6 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter FKBP_C PF00254.28 EWM24621.1 - 1.3e-15 57.5 0.0 2e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF2476 PF10630.9 EWM24621.1 - 0.14 12.3 1.3 0.22 11.6 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2476) Sds3 PF08598.11 EWM24622.1 - 3.5e-13 50.1 12.0 5.8e-13 49.3 12.0 1.3 1 0 0 1 1 1 1 Sds3-like eIF-5a PF01287.20 EWM24622.1 - 0.00067 19.7 0.0 0.0018 18.3 0.0 1.7 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold XhlA PF10779.9 EWM24622.1 - 2 8.7 3.8 0.89 9.8 0.4 2.1 2 0 0 2 2 2 0 Haemolysin XhlA EF-hand_13 PF17958.1 EWM24623.1 - 2.3e-32 110.7 0.0 7.9e-32 108.9 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 EWM24623.1 - 4.4e-18 65.5 5.8 5.7e-17 61.9 1.4 3.1 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 EWM24623.1 - 2.2e-08 33.2 0.4 0.008 15.6 0.0 3.8 3 0 0 3 3 3 2 EF hand EF-hand_1 PF00036.32 EWM24623.1 - 1.3e-07 30.6 0.0 0.031 13.8 0.0 3.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EWM24623.1 - 2.4e-07 30.1 0.1 0.13 12.3 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 EWM24623.1 - 0.00024 20.9 0.6 0.29 11.0 0.0 3.6 3 1 0 3 3 3 1 EF-hand domain pair Sec34 PF04136.15 EWM24623.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Sec34-like family UIM PF02809.20 EWM24624.1 - 0.16 12.0 17.8 1.9 8.6 0.1 4.1 3 0 0 3 3 3 0 Ubiquitin interaction motif MerC PF03203.14 EWM24624.1 - 0.23 11.9 0.3 0.42 11.1 0.3 1.3 1 0 0 1 1 1 0 MerC mercury resistance protein RabGAP-TBC PF00566.18 EWM24625.1 - 2.1e-24 86.4 0.0 3.3e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ank_2 PF12796.7 EWM24625.1 - 4.7e-17 62.3 0.1 1.1e-12 48.3 0.3 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EWM24625.1 - 6e-15 55.4 0.7 6.6e-05 23.4 0.2 3.9 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EWM24625.1 - 5.8e-13 48.8 1.7 3.1e-07 30.5 0.4 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EWM24625.1 - 2.1e-10 40.6 14.1 0.019 15.4 0.1 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 EWM24625.1 - 3.3e-10 39.3 5.0 0.01 16.3 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat PA PF02225.22 EWM24625.1 - 2.1e-07 30.9 0.1 5.2e-07 29.6 0.1 1.6 1 0 0 1 1 1 1 PA domain PAP_fibrillin PF04755.12 EWM24627.1 - 1.2e-10 41.7 0.0 1.8e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 PAP_fibrillin EF-hand_7 PF13499.6 EWM24628.1 - 2.3e-08 34.4 0.2 0.0027 18.1 0.0 4.2 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_13 PF17958.1 EWM24628.1 - 0.00026 20.7 0.1 0.0013 18.5 0.0 2.3 2 1 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EWM24628.1 - 0.00049 19.5 0.0 5.2 6.9 0.0 4.6 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 EWM24628.1 - 0.0068 16.2 0.1 5.4 7.2 0.0 4.1 4 0 0 4 4 4 1 EF-hand domain Mito_fiss_reg PF05308.11 EWM24628.1 - 0.38 10.8 2.5 0.42 10.7 0.2 1.9 2 0 0 2 2 2 0 Mitochondrial fission regulator DUF1275 PF06912.11 EWM24629.1 - 7.6e-26 91.2 14.6 1e-25 90.8 14.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) WD40 PF00400.32 EWM24630.1 - 3.2e-26 91.1 9.5 7.6e-07 29.7 0.2 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM24630.1 - 1.6e-10 41.1 0.2 0.0019 18.4 0.0 4.9 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EWM24630.1 - 0.0054 16.6 0.0 13 5.6 0.0 3.5 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Transket_pyr PF02779.24 EWM24631.1 - 3.6e-66 222.2 0.0 7.7e-66 221.1 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 EWM24631.1 - 3.4e-59 200.3 0.0 5.2e-59 199.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 EWM24631.1 - 1.2e-50 171.2 0.0 2.1e-50 170.4 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 EWM24631.1 - 1.1e-18 66.5 0.5 2.6e-18 65.3 0.5 1.7 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus Sad1_UNC PF07738.13 EWM24632.1 - 3.6e-23 82.0 0.0 6.4e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal F5_F8_type_C PF00754.25 EWM24632.1 - 1.9e-07 31.2 0.0 4.2e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain rve PF00665.26 EWM24634.1 - 1.4e-14 54.3 0.0 2.1e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain MIF4G PF02854.19 EWM24635.1 - 2.6e-39 135.1 4.4 1.1e-38 133.1 5.5 1.4 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.17 EWM24635.1 - 0.001 19.0 0.0 0.0029 17.6 0.0 1.8 2 0 0 2 2 2 1 MA3 domain CNOT1_CAF1_bind PF16415.5 EWM24635.1 - 0.18 11.1 0.0 0.37 10.2 0.0 1.4 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 CAF1-binding domain Atx10homo_assoc PF09759.9 EWM24636.1 - 3.2e-13 49.5 9.9 0.0024 17.9 0.0 7.4 6 1 1 7 7 7 2 Spinocerebellar ataxia type 10 protein domain zf-RING_2 PF13639.6 EWM24636.1 - 9.8e-09 35.4 14.4 6.2e-08 32.8 14.4 2.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EWM24636.1 - 0.00038 20.7 11.1 0.0014 18.9 11.1 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EWM24636.1 - 0.0053 16.6 14.8 0.0053 16.6 14.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF4704 PF15787.5 EWM24636.1 - 0.011 15.1 1.9 0.078 12.2 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4704) zf-ANAPC11 PF12861.7 EWM24636.1 - 0.018 15.1 3.1 0.061 13.4 3.1 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger WAPL PF07814.13 EWM24636.1 - 0.028 13.2 10.9 0.16 10.7 0.1 4.5 4 1 2 6 6 6 0 Wings apart-like protein regulation of heterochromatin zf-C3HC4_3 PF13920.6 EWM24636.1 - 0.035 14.0 9.0 0.12 12.3 9.0 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) N1221 PF07923.13 EWM24636.1 - 0.17 11.1 0.5 1.9 7.6 0.1 2.2 2 0 0 2 2 2 0 N1221-like protein zf-RING_11 PF17123.5 EWM24636.1 - 0.4 10.5 4.5 1.8 8.4 4.5 2.2 1 0 0 1 1 1 0 RING-like zinc finger RINGv PF12906.7 EWM24636.1 - 2.6 8.2 12.3 7.8 6.7 12.3 1.9 1 0 0 1 1 1 0 RING-variant domain TRAPP PF04051.16 EWM24637.1 - 6.7e-40 136.2 0.0 7.8e-40 136.0 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Ala_racemase_N PF01168.20 EWM24638.1 - 1e-24 87.4 0.6 1.5e-24 86.8 0.6 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain HLH PF00010.26 EWM24640.1 - 1.7e-05 24.7 0.7 3.6e-05 23.6 0.7 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TFIIA PF03153.13 EWM24640.1 - 0.12 12.3 19.6 0.026 14.5 16.1 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 EWM24640.1 - 3.6 5.7 19.2 4.8 5.3 19.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Exo_endo_phos PF03372.23 EWM24644.1 - 2.3e-10 40.4 0.0 8.6e-10 38.5 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 EWM24644.1 - 0.0033 17.5 0.7 0.0033 17.5 0.7 2.2 2 0 0 2 2 2 1 GRF zinc finger DUF3987 PF13148.6 EWM24644.1 - 0.045 12.8 0.0 0.15 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) V-SNARE_C PF12352.8 EWM24646.1 - 5e-12 45.9 1.7 3.2e-11 43.3 1.1 2.0 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EWM24646.1 - 0.012 15.5 0.0 0.047 13.6 0.0 1.8 2 0 0 2 2 2 0 Sec20 Pkinase PF00069.25 EWM24647.1 - 5.8e-52 176.7 0.0 8.7e-51 172.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM24647.1 - 8.1e-23 81.0 0.0 1.2e-14 54.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EWM24647.1 - 4.8e-05 22.8 0.0 0.72 9.1 0.0 3.1 3 0 0 3 3 3 2 Kinase-like PH PF00169.29 EWM24647.1 - 0.00011 22.7 0.0 0.021 15.3 0.0 2.7 3 0 0 3 3 3 1 PH domain Pkinase_fungal PF17667.1 EWM24647.1 - 0.00071 18.5 0.0 0.0015 17.4 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EWM24647.1 - 0.0026 17.2 0.0 0.0053 16.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Methyltransf_11 PF08241.12 EWM24648.1 - 1.9e-12 47.7 0.0 3e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM24648.1 - 5.2e-10 39.3 0.0 7e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM24648.1 - 4.6e-09 36.9 0.1 9.5e-09 35.9 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EWM24648.1 - 0.00058 20.6 0.0 0.0011 19.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EWM24648.1 - 0.014 14.7 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TPMT PF05724.11 EWM24648.1 - 0.018 14.7 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_29 PF03141.16 EWM24648.1 - 0.058 12.0 0.0 0.085 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase BPL_LplA_LipB PF03099.19 EWM24649.1 - 5.7e-06 26.3 0.0 9.9e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family NPR3 PF03666.13 EWM24650.1 - 3.4e-27 95.4 0.0 4.3e-24 85.1 0.0 2.3 2 0 0 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 DNA_ligase_A_M PF01068.21 EWM24654.1 - 3.2e-58 196.8 0.0 1.2e-57 194.9 0.0 1.9 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EWM24654.1 - 5.8e-32 111.4 0.0 1.3e-31 110.2 0.0 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EWM24654.1 - 4.2e-22 78.6 0.0 1.2e-21 77.1 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.6 EWM24654.1 - 0.095 12.7 0.3 4.4 7.4 0.0 2.6 2 0 0 2 2 2 0 DNA ligase OB-like domain RVT_2 PF07727.14 EWM24655.1 - 4.1e-67 226.3 0.0 5.7e-67 225.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C3HC4_3 PF13920.6 EWM24656.1 - 8.9e-10 38.3 4.3 1.9e-09 37.3 4.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EWM24656.1 - 1.5e-09 38.0 9.0 1.5e-09 38.0 9.0 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EWM24656.1 - 2.2e-09 37.0 7.9 3.6e-09 36.3 7.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EWM24656.1 - 1.9e-08 34.0 6.8 4e-08 33.0 6.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EWM24656.1 - 8.5e-08 32.0 5.2 1.5e-07 31.2 5.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EWM24656.1 - 1.7e-06 27.9 8.1 3.7e-06 26.9 8.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EWM24656.1 - 2.9e-06 27.0 5.5 6e-06 26.0 5.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EWM24656.1 - 2.3e-05 24.6 5.9 5.4e-05 23.4 5.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EWM24656.1 - 0.00086 19.4 9.7 0.0015 18.6 9.7 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Rtf2 PF04641.12 EWM24656.1 - 0.022 14.1 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger zf-RING_11 PF17123.5 EWM24656.1 - 1.4 8.7 5.5 0.24 11.2 1.6 1.8 2 0 0 2 2 2 0 RING-like zinc finger zf-LITAF-like PF10601.9 EWM24656.1 - 8 6.8 10.3 11 6.3 8.8 2.1 2 1 0 2 2 2 0 LITAF-like zinc ribbon domain Patatin PF01734.22 EWM24657.1 - 5.4e-14 52.8 0.0 1.4e-13 51.5 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase JAKMIP_CC3 PF16034.5 EWM24657.1 - 0.0029 17.6 0.4 0.0045 17.0 0.4 1.2 1 0 0 1 1 1 1 JAKMIP CC3 domain GIT_CC PF16559.5 EWM24657.1 - 0.015 15.2 1.0 0.032 14.1 1.0 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor ZapB PF06005.12 EWM24657.1 - 0.074 13.5 1.7 0.13 12.7 1.7 1.3 1 0 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 EWM24657.1 - 0.15 11.9 0.9 0.27 11.0 0.9 1.3 1 0 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.21 EWM24657.1 - 0.16 12.1 1.2 0.64 10.2 0.4 2.2 2 0 0 2 2 2 0 bZIP transcription factor KASH_CCD PF14662.6 EWM24657.1 - 0.25 11.1 2.3 0.42 10.4 2.3 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH SlyX PF04102.12 EWM24657.1 - 0.27 11.9 2.1 0.56 10.9 2.1 1.5 1 0 0 1 1 1 0 SlyX Patatin PF01734.22 EWM24658.1 - 1.3e-19 71.2 0.0 3.3e-19 69.9 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase DUF3336 PF11815.8 EWM24658.1 - 1.3e-18 67.0 1.8 2.1e-18 66.4 0.8 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) JAKMIP_CC3 PF16034.5 EWM24658.1 - 0.0058 16.6 5.4 0.0065 16.5 0.4 2.2 2 0 0 2 2 2 1 JAKMIP CC3 domain GIT_CC PF16559.5 EWM24658.1 - 0.018 14.9 1.0 0.043 13.7 1.0 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Paramyxo_P PF01806.17 EWM24658.1 - 0.076 12.4 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Paramyxovirinae P phosphoprotein C-terminal region ZapB PF06005.12 EWM24658.1 - 0.077 13.4 1.7 0.18 12.3 1.7 1.6 1 0 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 EWM24658.1 - 0.12 12.1 0.9 0.37 10.6 0.9 1.8 1 0 0 1 1 1 0 Septum formation initiator SlyX PF04102.12 EWM24658.1 - 3.7 8.2 6.4 0.76 10.4 2.1 2.0 2 0 0 2 2 2 0 SlyX Roc PF08477.13 EWM24659.1 - 0.00019 21.6 0.0 0.00037 20.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EWM24659.1 - 0.001 18.7 0.0 0.0024 17.5 0.0 1.6 2 0 0 2 2 2 1 Ras family AAA_16 PF13191.6 EWM24659.1 - 0.016 15.6 0.1 0.043 14.2 0.1 1.7 1 0 0 1 1 1 0 AAA ATPase domain Arf PF00025.21 EWM24659.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family DAP3 PF10236.9 EWM24659.1 - 0.17 11.0 0.1 0.3 10.2 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 WD40 PF00400.32 EWM24660.1 - 5.3e-07 30.2 12.5 0.0015 19.3 1.2 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat TPR_1 PF00515.28 EWM24660.1 - 3.4e-06 26.6 7.1 0.0033 17.2 0.0 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EWM24660.1 - 1.1e-05 25.1 1.0 0.12 12.5 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EWM24660.1 - 9.8e-05 22.9 0.5 0.00028 21.4 0.5 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 EWM24660.1 - 0.00069 19.6 0.7 0.21 11.9 0.4 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EWM24660.1 - 0.0016 18.4 0.0 0.0047 16.9 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 EWM24660.1 - 0.0089 16.3 0.3 0.47 11.0 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EWM24660.1 - 0.013 15.6 0.3 0.04 14.1 0.3 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 EWM24660.1 - 0.023 14.4 0.5 1.9 8.2 0.1 2.9 2 1 0 2 2 2 0 TPR repeat ANAPC4_WD40 PF12894.7 EWM24660.1 - 0.04 14.2 0.0 0.25 11.6 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain TPR_14 PF13428.6 EWM24660.1 - 0.044 14.6 0.3 3.3 8.8 0.1 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat NUP50 PF08911.11 EWM24660.1 - 0.066 13.9 0.4 7.1 7.4 0.1 2.5 2 0 0 2 2 2 0 NUP50 (Nucleoporin 50 kDa) DcpS_C PF11969.8 EWM24661.1 - 4.6e-21 75.4 0.1 6e-21 75.0 0.1 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 EWM24661.1 - 3.7e-06 27.6 0.2 7e-06 26.7 0.2 1.4 1 0 0 1 1 1 1 HIT domain NAP PF00956.18 EWM24661.1 - 0.0031 16.7 0.0 0.0034 16.6 0.0 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Peptidase_C69 PF03577.15 EWM24662.1 - 3.5e-51 174.4 0.0 4.8e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C69 Peptidase_C69 PF03577.15 EWM24663.1 - 9.8e-64 215.7 0.0 1.5e-62 211.9 0.0 2.0 1 1 1 2 2 2 2 Peptidase family C69 Amidase PF01425.21 EWM24666.1 - 6.8e-128 427.4 2.4 2.1e-126 422.6 2.4 2.0 1 1 0 1 1 1 1 Amidase DUF3172 PF11371.8 EWM24667.1 - 7.9e-54 181.1 0.2 1e-53 180.8 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3172) ABC2_membrane PF01061.24 EWM24668.1 - 1e-23 83.9 28.1 1.8e-23 83.1 28.1 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EWM24668.1 - 2.9e-19 69.9 0.0 4.4e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EWM24668.1 - 2.2e-06 27.7 0.0 0.013 15.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 EWM24668.1 - 0.00079 18.6 23.0 0.00079 18.6 23.0 1.8 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_22 PF13401.6 EWM24668.1 - 0.0019 18.5 0.0 0.83 9.9 0.0 2.8 2 1 1 3 3 3 2 AAA domain SMC_N PF02463.19 EWM24668.1 - 0.0043 16.5 0.0 0.0068 15.9 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EWM24668.1 - 0.022 15.3 0.0 0.044 14.3 0.0 1.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EWM24668.1 - 0.14 12.5 0.0 0.42 11.0 0.0 1.8 1 1 1 2 2 2 0 AAA ATPase domain SbcCD_C PF13558.6 EWM24668.1 - 0.18 12.1 0.1 1.5 9.1 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit CCT PF06203.14 EWM24669.1 - 2.1e-15 56.5 14.3 3e-15 56.0 14.3 1.2 1 0 0 1 1 1 1 CCT motif PAP_fibrillin PF04755.12 EWM24670.1 - 2.2e-10 40.8 0.0 2.4e-09 37.4 0.0 2.1 1 1 0 1 1 1 1 PAP_fibrillin RRM_1 PF00076.22 EWM24674.1 - 4.3e-21 74.5 0.0 5.9e-21 74.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Y_phosphatase3 PF13350.6 EWM24675.1 - 0.018 15.1 0.0 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family CENP-T_C PF15511.6 EWM24676.1 - 3.1e-08 33.7 0.1 3.8e-08 33.4 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EWM24676.1 - 0.00036 20.8 0.1 0.00048 20.5 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 EWM24676.1 - 0.00057 20.0 0.1 0.0008 19.5 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EWM24676.1 - 0.004 17.4 0.0 0.0067 16.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EWM24676.1 - 0.0089 16.4 0.2 0.0099 16.2 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EWM24676.1 - 0.053 13.6 0.0 0.06 13.4 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EWM24676.1 - 0.1 12.6 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated Amino_oxidase PF01593.24 EWM24677.1 - 3.6e-17 62.8 0.1 5.9e-17 62.1 0.1 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EWM24677.1 - 2.4e-13 50.1 0.3 8.3e-13 48.4 0.3 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EWM24677.1 - 4e-09 36.5 0.6 0.00058 19.5 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EWM24677.1 - 1e-08 34.7 4.4 1.2e-06 27.9 4.4 2.7 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EWM24677.1 - 1.4e-05 24.5 0.4 3.4e-05 23.2 0.1 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 EWM24677.1 - 0.00049 19.4 0.1 0.00087 18.6 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EWM24677.1 - 0.0006 18.6 0.1 0.19 10.4 0.2 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 EWM24677.1 - 0.0012 18.2 0.9 0.0022 17.4 0.9 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GMC_oxred_N PF00732.19 EWM24677.1 - 0.0018 17.7 0.1 0.0031 17.0 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase MFS_1 PF07690.16 EWM24677.1 - 0.014 14.4 0.2 0.033 13.1 0.2 1.5 1 0 0 1 1 1 0 Major Facilitator Superfamily FAD_binding_3 PF01494.19 EWM24677.1 - 0.14 11.3 0.5 0.23 10.7 0.5 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 EWM24677.1 - 0.16 11.0 2.6 0.43 9.6 0.5 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.27 EWM24677.1 - 0.34 11.5 2.8 1.7 9.3 0.7 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SNARE_assoc PF09335.11 EWM24678.1 - 2.3e-21 76.5 6.1 5.3e-21 75.3 6.1 1.7 1 0 0 1 1 1 1 SNARE associated Golgi protein DUF456 PF04306.13 EWM24678.1 - 0.0072 16.6 12.6 0.031 14.6 0.1 2.4 3 0 0 3 3 3 2 Protein of unknown function (DUF456) MaAIMP_sms PF16951.5 EWM24679.1 - 0.086 12.6 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Putative methionine and alanine importer, small subunit Porphobil_deam PF01379.20 EWM24679.1 - 0.14 11.6 0.1 0.41 10.1 0.0 1.7 2 0 0 2 2 2 0 Porphobilinogen deaminase, dipyromethane cofactor binding domain RNase_H2_suC PF08615.11 EWM24680.1 - 5.6e-09 36.3 0.0 6.2e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Ead_Ea22 PF13935.6 EWM24681.1 - 0.00038 21.1 1.3 0.4 11.3 0.0 2.6 2 0 0 2 2 2 2 Ead/Ea22-like protein BicD PF09730.9 EWM24681.1 - 0.0049 15.4 2.8 0.01 14.3 2.8 1.4 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D EMP24_GP25L PF01105.24 EWM24681.1 - 0.031 14.2 0.4 0.093 12.7 0.0 2.0 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD EIAV_Rev PF11129.8 EWM24681.1 - 0.05 13.8 0.8 0.13 12.5 0.8 1.7 1 0 0 1 1 1 0 Rev protein of equine infectious anaemia virus Pox_A_type_inc PF04508.12 EWM24681.1 - 0.057 13.3 0.3 0.21 11.5 0.3 2.0 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Peptidase_S24 PF00717.23 EWM24682.1 - 1.5e-12 47.3 0.0 2.3e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 EWM24682.1 - 3e-05 23.8 0.0 0.013 15.3 0.0 2.9 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Pkinase PF00069.25 EWM24683.1 - 2.4e-56 191.0 0.0 1.5e-51 175.3 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EWM24683.1 - 1.6e-36 126.0 0.0 2.1e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EWM24683.1 - 0.0045 16.4 0.0 0.073 12.4 0.0 2.4 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EWM24683.1 - 0.046 12.5 0.0 0.07 11.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase UbiA PF01040.18 EWM24684.1 - 2.9e-53 180.8 13.8 4.1e-53 180.3 13.6 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family Histone PF00125.24 EWM24685.1 - 2.5e-52 176.7 1.5 2.8e-52 176.5 1.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EWM24685.1 - 0.00025 21.3 0.0 0.00038 20.8 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EWM24685.1 - 0.00029 20.9 0.4 0.00046 20.3 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EWM24685.1 - 0.00038 21.1 2.1 0.00048 20.7 2.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 EWM24685.1 - 0.021 15.1 0.0 0.041 14.2 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EWM24685.1 - 0.11 12.6 0.2 0.19 11.8 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit EMP70 PF02990.16 EWM24686.1 - 1.3e-203 677.5 5.8 1.9e-203 676.8 5.8 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Leu_leader PF08054.11 EWM24686.1 - 0.053 13.1 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Leucine operon leader peptide FliJ PF02050.16 EWM24687.1 - 4.1 7.6 8.7 0.64 10.3 1.3 2.4 2 0 0 2 2 2 0 Flagellar FliJ protein zf-RanBP PF00641.18 EWM24688.1 - 3.2e-08 32.7 6.1 4.7e-08 32.2 6.1 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others WW PF00397.26 EWM24688.1 - 9.6e-08 32.0 4.9 1.9e-07 31.1 4.9 1.6 1 0 0 1 1 1 1 WW domain Glyco_hyd_101C PF17451.2 EWM24688.1 - 0.00053 20.3 0.3 0.00075 19.8 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase 101 beta sandwich domain zf-Sec23_Sec24 PF04810.15 EWM24688.1 - 0.35 11.0 4.6 0.86 9.7 0.1 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger IBR PF01485.21 EWM24689.1 - 1.3e-13 51.0 16.5 3.3e-08 33.6 8.1 2.3 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain Biotin_lipoyl PF00364.22 EWM24690.1 - 5.6e-16 58.1 4.2 7.5e-16 57.7 4.2 1.2 1 0 0 1 1 1 1 Biotin-requiring enzyme GCV_H PF01597.19 EWM24690.1 - 0.065 13.1 0.7 0.093 12.6 0.7 1.2 1 0 0 1 1 1 0 Glycine cleavage H-protein MSA-2c PF12238.8 EWM24690.1 - 0.29 11.1 5.6 0.39 10.7 5.6 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c Biotin_lipoyl_2 PF13533.6 EWM24690.1 - 0.31 10.9 3.4 0.28 11.0 0.7 2.1 1 1 1 2 2 2 0 Biotin-lipoyl like Ufd2P_core PF10408.9 EWM24691.1 - 1.6e-81 274.8 0.0 2.1e-81 274.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 EWM24691.1 - 2.6e-26 91.6 0.2 1e-25 89.7 0.2 2.0 2 0 0 2 2 2 1 U-box domain Arc PF03869.14 EWM24691.1 - 0.051 13.4 0.3 0.65 9.9 0.4 2.5 2 0 0 2 2 2 0 Arc-like DNA binding domain DUF1848 PF08902.11 EWM24691.1 - 0.064 13.0 0.0 0.27 10.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1848) ABC_tran PF00005.27 EWM24693.1 - 2.5e-12 47.5 0.0 9.3e-12 45.6 0.0 2.0 1 1 0 1 1 1 1 ABC transporter HEAT PF02985.22 EWM24693.1 - 1.2e-07 31.4 2.3 0.0023 18.0 0.0 5.3 5 0 0 5 5 4 1 HEAT repeat Cnd1 PF12717.7 EWM24693.1 - 6.6e-05 23.0 0.5 0.00037 20.6 0.2 2.1 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 AAA_21 PF13304.6 EWM24693.1 - 7.8e-05 22.6 0.0 0.001 19.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EWM24693.1 - 0.0039 16.9 0.0 0.0075 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_27 PF13514.6 EWM24693.1 - 0.0048 16.5 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain DCB PF16213.5 EWM24693.1 - 0.0096 15.6 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 AAA_23 PF13476.6 EWM24693.1 - 0.011 16.3 0.1 0.023 15.2 0.0 1.5 2 0 0 2 2 1 0 AAA domain Adaptin_N PF01602.20 EWM24693.1 - 0.013 14.1 0.4 0.036 12.6 0.1 1.6 1 1 0 1 1 1 0 Adaptin N terminal region HEAT_2 PF13646.6 EWM24693.1 - 0.015 15.7 1.0 0.32 11.4 0.0 3.0 2 1 2 4 4 4 0 HEAT repeats HEAT_EZ PF13513.6 EWM24693.1 - 0.017 15.6 8.7 5.3 7.6 0.0 5.1 6 0 0 6 6 5 0 HEAT-like repeat DUF1981 PF09324.10 EWM24693.1 - 0.019 14.8 0.1 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) ATPase_2 PF01637.18 EWM24693.1 - 0.024 14.6 0.0 0.065 13.1 0.0 1.7 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Ipi1_N PF12333.8 EWM24693.1 - 0.035 14.7 0.0 16 6.2 0.0 3.3 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation Vac14_Fab1_bd PF12755.7 EWM24693.1 - 0.038 14.6 0.0 0.22 12.1 0.0 2.3 2 1 0 2 2 2 0 Vacuolar 14 Fab1-binding region AAA_14 PF13173.6 EWM24693.1 - 0.042 13.9 0.0 0.4 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EWM24693.1 - 0.089 12.9 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 EWM24693.1 - 0.096 12.4 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 EWM24693.1 - 0.11 13.0 0.0 0.7 10.3 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CLASP_N PF12348.8 EWM24693.1 - 0.11 12.0 0.1 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 CLASP N terminal UTP15_C PF09384.10 EWM24693.1 - 0.16 11.7 0.1 0.99 9.1 0.0 2.4 2 2 1 3 3 3 0 UTP15 C terminal DRIM PF07539.12 EWM24693.1 - 0.16 10.2 0.2 3 6.0 0.0 2.1 1 1 1 2 2 2 0 Down-regulated in metastasis DUF326 PF03860.16 EWM24693.1 - 1.2 9.3 5.8 2.4 8.3 0.6 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF326) Lar_N PF09861.9 EWM24694.1 - 2.9e-09 36.4 0.0 4.3e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Lactate racemase N-terminal domain ABC_tran PF00005.27 EWM24696.1 - 7e-24 84.9 0.1 4.2e-22 79.1 0.0 2.9 2 1 0 2 2 2 1 ABC transporter Chromo PF00385.24 EWM24696.1 - 5e-08 32.7 0.8 1.3e-07 31.4 0.8 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SMC_N PF02463.19 EWM24696.1 - 2.4e-07 30.4 1.2 1.4e-06 27.9 0.1 2.5 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EWM24696.1 - 7.1e-05 22.7 3.5 0.014 15.2 0.5 2.7 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 EWM24696.1 - 0.0046 17.1 2.0 0.028 14.5 0.0 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_15 PF13175.6 EWM24696.1 - 0.0066 16.2 3.8 0.23 11.1 3.8 2.6 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 EWM24696.1 - 0.012 15.6 0.1 0.046 13.8 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EWM24696.1 - 0.025 14.5 0.5 0.068 13.1 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_30 PF13604.6 EWM24696.1 - 0.026 14.2 0.0 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EWM24696.1 - 0.029 14.1 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EWM24696.1 - 0.065 13.5 0.0 0.26 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EWM24696.1 - 0.095 12.9 0.0 0.54 10.5 0.0 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA PF00004.29 EWM24696.1 - 0.097 13.1 0.2 1.1 9.7 0.0 2.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EWM24696.1 - 0.12 12.6 0.0 0.31 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EWM24696.1 - 0.64 10.1 4.0 0.22 11.5 0.1 2.2 2 1 0 2 2 2 0 Dynamin family TRAF_BIRC3_bd PF16673.5 EWM24696.1 - 1.8 8.4 7.8 3 7.7 1.0 2.7 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain SAPS PF04499.15 EWM24697.1 - 0.038 12.8 5.1 0.058 12.2 5.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Zip PF02535.22 EWM24697.1 - 0.76 8.9 6.5 1.5 8.0 6.5 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Nop14 PF04147.12 EWM24697.1 - 0.84 7.8 20.7 1.3 7.1 20.7 1.2 1 0 0 1 1 1 0 Nop14-like family DUF913 PF06025.12 EWM24697.1 - 0.9 8.4 6.1 1.7 7.5 6.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CDC45 PF02724.14 EWM24697.1 - 1.1 7.5 15.7 1.8 6.7 15.7 1.3 1 0 0 1 1 1 0 CDC45-like protein Spore_coat_CotO PF14153.6 EWM24697.1 - 1.8 8.5 21.1 3.6 7.5 21.1 1.4 1 0 0 1 1 1 0 Spore coat protein CotO FGF-BP1 PF06473.12 EWM24697.1 - 2.1 8.1 20.0 0.013 15.3 10.7 1.9 2 1 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) FAM60A PF15396.6 EWM24697.1 - 2.6 8.0 7.9 6.5 6.7 7.9 1.6 1 0 0 1 1 1 0 Protein Family FAM60A Med3 PF11593.8 EWM24697.1 - 3.8 6.6 5.9 7 5.7 5.9 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Neur_chan_memb PF02932.16 EWM24697.1 - 4.3 7.3 8.0 1.4 8.9 3.4 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Spt20 PF12090.8 EWM24697.1 - 6.6 6.3 17.8 13 5.3 17.8 1.4 1 0 0 1 1 1 0 Spt20 family Smg8_Smg9 PF10220.9 EWM24697.1 - 8.1 4.6 8.5 12 4.0 8.5 1.2 1 0 0 1 1 1 0 Smg8_Smg9 SAPS PF04499.15 EWM24698.1 - 0.038 12.8 5.1 0.058 12.2 5.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Zip PF02535.22 EWM24698.1 - 0.76 8.9 6.5 1.5 8.0 6.5 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Nop14 PF04147.12 EWM24698.1 - 0.84 7.8 20.7 1.3 7.1 20.7 1.2 1 0 0 1 1 1 0 Nop14-like family DUF913 PF06025.12 EWM24698.1 - 0.9 8.4 6.1 1.7 7.5 6.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CDC45 PF02724.14 EWM24698.1 - 1.1 7.5 15.7 1.8 6.7 15.7 1.3 1 0 0 1 1 1 0 CDC45-like protein Spore_coat_CotO PF14153.6 EWM24698.1 - 1.8 8.5 21.1 3.6 7.5 21.1 1.4 1 0 0 1 1 1 0 Spore coat protein CotO FGF-BP1 PF06473.12 EWM24698.1 - 2.1 8.1 20.0 0.013 15.3 10.7 1.9 2 1 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) FAM60A PF15396.6 EWM24698.1 - 2.6 8.0 7.9 6.5 6.7 7.9 1.6 1 0 0 1 1 1 0 Protein Family FAM60A Med3 PF11593.8 EWM24698.1 - 3.8 6.6 5.9 7 5.7 5.9 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Neur_chan_memb PF02932.16 EWM24698.1 - 4.3 7.3 8.0 1.4 8.9 3.4 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Spt20 PF12090.8 EWM24698.1 - 6.6 6.3 17.8 13 5.3 17.8 1.4 1 0 0 1 1 1 0 Spt20 family Smg8_Smg9 PF10220.9 EWM24698.1 - 8.1 4.6 8.5 12 4.0 8.5 1.2 1 0 0 1 1 1 0 Smg8_Smg9 MbeD_MobD PF04899.12 EWM24699.1 - 0.018 15.1 0.4 0.041 14.0 0.4 1.6 1 0 0 1 1 1 0 MbeD/MobD like DUF2357 PF09823.9 EWM24699.1 - 0.026 13.8 0.7 0.043 13.1 0.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF2357) ATG16 PF08614.11 EWM24699.1 - 0.094 12.9 10.2 0.16 12.2 10.2 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) iPGM_N PF06415.13 EWM24699.1 - 0.18 11.2 0.5 0.29 10.6 0.5 1.3 1 0 0 1 1 1 0 BPG-independent PGAM N-terminus (iPGM_N) FUSC PF04632.12 EWM24699.1 - 0.18 10.3 3.3 0.24 9.9 3.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF16 PF01519.16 EWM24699.1 - 0.43 11.1 2.1 0.77 10.3 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 DivIC PF04977.15 EWM24699.1 - 0.52 10.1 5.6 0.42 10.4 1.2 2.3 1 1 1 2 2 2 0 Septum formation initiator Spc7 PF08317.11 EWM24699.1 - 0.78 8.6 9.1 1.2 7.9 9.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DNA_mis_repair PF01119.19 EWM24700.1 - 3.9e-27 94.3 0.0 6.7e-27 93.5 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EWM24700.1 - 2.8e-11 43.4 0.0 5.6e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EWM24700.1 - 1.1e-05 25.9 0.0 2.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CAP_N PF01213.19 EWM24701.1 - 2.3e-64 217.9 3.0 2.3e-64 217.9 3.0 1.7 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 EWM24701.1 - 6.8e-45 152.5 0.0 1.3e-44 151.6 0.0 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Ribosomal_60s PF00428.19 EWM24701.1 - 0.029 14.9 0.3 0.13 12.9 0.0 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Afi1 PF07792.12 EWM24701.1 - 0.081 13.4 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking TBCC PF07986.12 EWM24701.1 - 0.13 12.0 0.2 0.25 11.1 0.2 1.5 1 0 0 1 1 1 0 Tubulin binding cofactor C PsbU PF06514.11 EWM24702.1 - 6.3e-30 103.0 0.0 9.1e-30 102.5 0.0 1.2 1 0 0 1 1 1 1 Photosystem II 12 kDa extrinsic protein (PsbU) HHH_3 PF12836.7 EWM24702.1 - 1.6e-06 28.2 0.0 2.5e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix motif INCENP_ARK-bind PF03941.15 EWM24703.1 - 4.1e-16 58.6 0.1 4.1e-16 58.6 0.1 2.2 3 0 0 3 3 3 1 Inner centromere protein, ARK binding region SAP PF02037.27 EWM24703.1 - 2.3e-11 43.2 0.4 5.6e-11 41.9 0.4 1.7 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 EWM24703.1 - 0.0014 18.3 2.2 0.0026 17.4 0.2 2.3 2 0 0 2 2 2 1 HeH/LEM domain Pkinase PF00069.25 EWM24704.1 - 1.7e-35 122.7 0.0 3.9e-22 78.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EWM24704.1 - 1.7e-08 34.1 0.0 0.0036 16.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 EWM24704.1 - 0.00038 19.9 0.0 0.00062 19.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EWM24704.1 - 0.02 14.8 0.1 0.047 13.6 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Involucrin_N PF10583.9 EWM24704.1 - 0.33 11.6 5.4 17 6.1 0.1 3.4 3 0 0 3 3 3 0 Involucrin of squamous epithelia N-terminus Thiolase_N PF00108.23 EWM24705.1 - 5.8e-76 255.3 2.4 1e-75 254.5 2.4 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EWM24705.1 - 4.5e-48 162.0 0.5 8.4e-48 161.1 0.5 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EWM24705.1 - 0.0026 17.4 0.4 0.009 15.6 0.4 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 EWM24705.1 - 0.0052 16.9 0.0 0.016 15.3 0.0 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal AhpC-TSA_2 PF13911.6 EWM24706.1 - 1.9e-18 66.7 0.0 3.5e-17 62.5 0.0 2.1 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme HSF_DNA-bind PF00447.17 EWM24707.1 - 5.3e-25 87.9 2.2 9.6e-25 87.0 2.2 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding APG9 PF04109.16 EWM24708.1 - 2.2e-149 498.5 0.1 2.6e-149 498.3 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 OST3_OST6 PF04756.13 EWM24709.1 - 1.7e-38 132.7 0.1 2.3e-38 132.2 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family BT1 PF03092.16 EWM24710.1 - 9.4e-87 291.4 8.7 9.3e-51 172.6 4.5 2.1 2 0 0 2 2 2 2 BT1 family PUCC PF03209.15 EWM24710.1 - 0.049 12.6 5.2 0.05 12.6 0.0 2.8 3 0 0 3 3 3 0 PUCC protein DUF2157 PF09925.9 EWM24710.1 - 1 9.1 5.6 0.41 10.4 2.4 2.1 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) Glyco_hydro_99 PF16317.5 EWM24711.1 - 8.1e-88 294.8 2.7 3.6e-87 292.7 2.7 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 99 Glyco_hydro_71 PF03659.14 EWM24711.1 - 0.00054 18.9 0.3 0.0021 17.0 0.5 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 Glyco_tran_WbsX PF14307.6 EWM24711.1 - 0.0098 15.4 0.0 0.051 13.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase WbsX zf-C3HC4 PF00097.25 EWM24712.1 - 0.00029 20.6 0.7 0.00029 20.6 0.7 2.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EWM24712.1 - 0.0003 20.7 9.1 0.0025 17.8 9.1 2.3 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EWM24712.1 - 0.0035 17.7 6.6 0.0069 16.7 0.8 2.6 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 EWM24712.1 - 0.017 14.9 0.1 0.017 14.9 0.1 2.5 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EWM24712.1 - 0.027 14.6 1.5 0.047 13.9 0.3 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EWM24712.1 - 3.5 7.7 7.4 0.69 9.9 1.4 2.5 3 0 0 3 3 3 0 zinc-RING finger domain zf-C3HC4 PF00097.25 EWM24713.1 - 0.00027 20.7 0.7 0.00027 20.7 0.7 2.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EWM24713.1 - 0.00038 20.4 9.6 0.0032 17.4 9.6 2.3 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EWM24713.1 - 0.0032 17.8 6.6 0.0064 16.8 0.8 2.5 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 EWM24713.1 - 0.016 15.0 0.1 0.016 15.0 0.1 2.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EWM24713.1 - 0.024 14.8 1.5 0.043 14.0 0.3 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EWM24713.1 - 0.23 11.5 3.3 0.64 10.0 1.4 2.2 2 0 0 2 2 2 0 zinc-RING finger domain ATG_C PF09333.11 EWM24714.1 - 7.9e-32 109.5 0.0 4.8e-29 100.6 0.0 2.3 2 0 0 2 2 2 2 Autophagy-related protein C terminal domain VPS13_C PF16909.5 EWM24714.1 - 0.0076 16.1 0.0 0.015 15.1 0.0 1.5 1 1 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal Yippee-Mis18 PF03226.14 EWM24716.1 - 1.2e-16 60.9 2.0 1.5e-16 60.5 2.0 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Chorein_N PF12624.7 EWM24717.1 - 4.4e-07 30.0 0.0 0.00029 20.9 0.0 2.1 2 0 0 2 2 2 2 N-terminal region of Chorein or VPS13 Pex2_Pex12 PF04757.14 EWM24718.1 - 9.1e-38 130.1 0.5 1.1e-37 129.8 0.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 EWM24718.1 - 0.0024 17.7 0.7 0.0043 16.9 0.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EWM24718.1 - 0.02 14.7 2.3 0.031 14.2 2.3 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2270 PF10028.9 EWM24718.1 - 0.092 12.3 1.0 6.8 6.2 0.0 2.3 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2270) zf-RING_2 PF13639.6 EWM24718.1 - 0.36 11.2 2.0 0.61 10.5 2.0 1.4 1 0 0 1 1 1 0 Ring finger domain PUMA PF15826.5 EWM24718.1 - 3.1 7.9 6.5 0.43 10.7 0.1 2.2 2 0 0 2 2 2 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis Tubulin PF00091.25 EWM24719.1 - 7.2e-70 235.2 0.0 1.4e-69 234.3 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EWM24719.1 - 1.4e-39 135.1 0.4 3e-39 134.1 0.4 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EWM24719.1 - 1.1e-05 25.8 0.0 2.1e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EWM24719.1 - 0.058 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain ThiF PF00899.21 EWM24721.1 - 3.1e-67 226.5 0.0 4.6e-67 225.9 0.0 1.2 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 EWM24721.1 - 5.6e-20 71.3 0.4 9.5e-20 70.5 0.4 1.4 1 0 0 1 1 1 1 E2 binding domain UAE_UbL PF14732.6 EWM24721.1 - 0.0045 17.6 0.0 0.015 15.9 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.20 EWM24721.1 - 0.0051 16.9 0.2 0.013 15.5 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Myb_DNA-binding PF00249.31 EWM24723.1 - 1.1e-23 83.1 1.6 5e-12 45.8 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Lipase_3 PF01764.25 EWM24723.1 - 9.6e-23 80.6 0.0 3.6e-22 78.8 0.0 1.9 1 1 0 1 1 1 1 Lipase (class 3) Myb_DNA-bind_6 PF13921.6 EWM24723.1 - 1.5e-20 73.2 1.0 2.9e-15 56.3 0.1 2.9 2 1 1 3 3 3 2 Myb-like DNA-binding domain DUF2974 PF11187.8 EWM24723.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) SLIDE PF09111.10 EWM24723.1 - 0.17 11.9 0.0 1.4 8.9 0.0 2.1 1 1 1 2 2 2 0 SLIDE zf-LYAR PF08790.11 EWM24724.1 - 7.2e-17 61.0 3.7 4.1e-15 55.4 1.4 2.3 2 0 0 2 2 2 2 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 EWM24724.1 - 0.0089 15.6 0.6 1.6 8.4 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger zf-ACC PF17848.1 EWM24724.1 - 0.012 15.7 1.3 0.02 15.0 0.1 2.0 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zf-TRAF PF02176.18 EWM24724.1 - 0.13 12.9 2.7 0.32 11.7 1.8 2.1 2 1 0 2 2 2 0 TRAF-type zinc finger DUF2956 PF11169.8 EWM24724.1 - 0.23 11.7 6.7 0.51 10.5 6.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) DUF2992 PF11208.8 EWM24724.1 - 0.87 9.8 11.2 1.5 9.0 11.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) zf-C2H2 PF00096.26 EWM24724.1 - 1.9 9.1 6.6 9 7.0 0.1 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type MAJIN PF15077.6 EWM24724.1 - 2.3 8.0 8.8 4.1 7.1 8.8 1.4 1 0 0 1 1 1 0 Membrane-anchored junction protein ATP-synt_I PF03899.15 EWM24725.1 - 0.015 15.6 8.3 0.03 14.7 8.3 1.6 1 0 0 1 1 1 0 ATP synthase I chain G-patch PF01585.23 EWM24726.1 - 1.4e-07 31.3 7.3 6.1e-07 29.2 7.3 2.2 1 0 0 1 1 1 1 G-patch domain DUF4226 PF10774.9 EWM24726.1 - 0.079 13.2 0.5 0.079 13.2 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) G-patch_2 PF12656.7 EWM24726.1 - 0.17 12.0 8.7 0.047 13.8 4.1 2.5 2 0 0 2 2 2 0 G-patch domain LDcluster4 PF18306.1 EWM24727.1 - 6.9e-32 110.2 0.0 9.7e-32 109.7 0.0 1.2 1 0 0 1 1 1 1 SLOG cluster4 family Cpn60_TCP1 PF00118.24 EWM24729.1 - 1.6e-167 558.1 0.0 1.8e-167 557.9 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Asn_synthase PF00733.21 EWM24730.1 - 1.1e-17 64.8 0.1 6.7e-17 62.2 0.1 1.9 1 1 1 2 2 2 1 Asparagine synthase NAD_synthase PF02540.17 EWM24730.1 - 0.0059 15.7 0.0 0.0082 15.3 0.0 1.3 1 0 0 1 1 1 1 NAD synthase QueC PF06508.13 EWM24730.1 - 0.049 13.1 0.0 0.21 11.0 0.0 1.9 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Diphthami_syn_2 PF01902.17 EWM24730.1 - 0.12 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Diphthamide synthase tRNA_Me_trans PF03054.16 EWM24730.1 - 0.16 10.7 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase PAPS_reduct PF01507.19 EWM24730.1 - 0.19 11.7 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Ank_2 PF12796.7 EWM24731.1 - 7.6e-11 42.5 0.0 4.1e-05 24.1 0.0 4.7 2 2 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EWM24731.1 - 4.4e-09 36.4 0.2 0.00014 22.1 0.0 4.4 2 1 3 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EWM24731.1 - 1.4e-05 25.5 0.0 0.55 10.9 0.0 4.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EWM24731.1 - 0.00022 21.5 0.0 11 6.7 0.0 4.7 4 1 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 EWM24731.1 - 0.0024 18.2 0.0 37 5.4 0.0 4.9 5 0 0 5 5 5 0 Ankyrin repeat DUF503 PF04456.12 EWM24731.1 - 0.044 13.7 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF503) Laminin_II PF06009.12 EWM24731.1 - 0.061 13.3 0.1 0.23 11.5 0.0 1.9 2 0 0 2 2 2 0 Laminin Domain II FAM184 PF15665.5 EWM24733.1 - 0.018 14.8 0.5 0.033 14.0 0.5 1.4 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B START PF01852.19 EWM24734.1 - 2.5e-06 27.0 0.0 4.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 START domain Cortex-I_coil PF09304.10 EWM24734.1 - 0.037 14.3 9.7 0.61 10.3 6.9 2.1 1 1 0 2 2 2 0 Cortexillin I, coiled coil DUF4527 PF15030.6 EWM24734.1 - 0.15 11.5 5.3 0.18 11.2 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) PI3_PI4_kinase PF00454.27 EWM24735.1 - 1.1e-29 104.0 0.0 1.8e-29 103.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase ubiquitin PF00240.23 EWM24735.1 - 2.4e-07 30.4 0.0 1e-06 28.4 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 EWM24735.1 - 0.2 11.5 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like PI3_PI4_kinase PF00454.27 EWM24736.1 - 2.5e-30 106.1 0.0 4e-30 105.4 0.0 1.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PALP PF00291.25 EWM24737.1 - 5.4e-64 216.4 2.6 9.4e-64 215.6 2.6 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Asp_Arg_Hydrox PF05118.15 EWM24738.1 - 1e-33 116.4 0.0 1.4e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Cupin_2 PF07883.11 EWM24738.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Cupin domain Lin0512_fam PF09585.10 EWM24740.1 - 3.5e-39 133.4 0.1 5.2e-39 132.8 0.1 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein (Lin0512_fam) NAC PF01849.18 EWM24741.1 - 2.9e-21 75.2 0.2 6e-21 74.2 0.2 1.6 1 0 0 1 1 1 1 NAC domain Fmp27 PF10344.9 EWM24741.1 - 0.23 9.5 1.8 0.28 9.3 1.8 1.0 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 RPN2_C PF18004.1 EWM24741.1 - 0.39 10.6 6.7 0.68 9.8 6.7 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF5523 PF17661.1 EWM24741.1 - 0.62 9.7 11.8 1 9.0 11.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5523) CDC45 PF02724.14 EWM24741.1 - 0.65 8.2 6.4 0.81 7.9 6.4 1.1 1 0 0 1 1 1 0 CDC45-like protein TrwC PF08751.11 EWM24741.1 - 0.73 9.3 4.8 1.1 8.7 4.8 1.2 1 0 0 1 1 1 0 TrwC relaxase DUF4746 PF15928.5 EWM24741.1 - 0.93 8.9 7.7 1.2 8.4 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PBP1_TM PF14812.6 EWM24741.1 - 1.8 9.0 4.9 3.9 7.9 4.9 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pox_Ag35 PF03286.14 EWM24741.1 - 5 6.9 8.4 8.9 6.0 8.4 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TFIIF_alpha PF05793.12 EWM24741.1 - 5.4 5.5 16.1 7.2 5.1 16.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PBP_sp32 PF07222.12 EWM24741.1 - 7.5 5.9 12.5 12 5.3 12.5 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Dpy19 PF10034.9 EWM24742.1 - 0.15 10.2 0.2 0.17 10.1 0.2 1.0 1 0 0 1 1 1 0 Q-cell neuroblast polarisation DIOX_N PF14226.6 EWM24743.1 - 5.7e-07 30.3 0.0 7.3e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal EP400_N PF15790.5 EWM24743.1 - 0.018 13.9 0.7 0.019 13.9 0.7 1.1 1 0 0 1 1 1 0 E1A-binding protein p400, N-terminal Gemini_AL2 PF01440.16 EWM24743.1 - 0.052 14.0 0.6 0.075 13.5 0.6 1.3 1 1 0 1 1 1 0 Geminivirus AL2 protein Peptidase_C54 PF03416.19 EWM24744.1 - 1.7e-22 80.1 0.0 2.4e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Peptidase_C54 PF03416.19 EWM24746.1 - 3.2e-16 59.6 0.4 4e-16 59.3 0.4 1.1 1 0 0 1 1 1 1 Peptidase family C54 DUF3000 PF11452.8 EWM24746.1 - 0.03 13.8 0.0 0.034 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3000) Peptidase_C78 PF07910.13 EWM24746.1 - 0.082 12.4 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 Peptidase family C78 MFS_1 PF07690.16 EWM24747.1 - 4.7e-12 45.5 15.3 9.1e-12 44.6 15.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EWM24747.1 - 0.0046 15.9 3.5 0.005 15.8 0.7 2.0 1 1 1 2 2 2 1 Sugar (and other) transporter 5-FTHF_cyc-lig PF01812.20 EWM24754.1 - 1.8e-11 44.3 0.1 2.4e-11 43.9 0.1 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Adipokin_hormo PF06377.11 EWM24754.1 - 0.15 12.5 0.3 0.35 11.2 0.3 1.6 1 0 0 1 1 1 0 Adipokinetic hormone RRM_1 PF00076.22 EWM24755.1 - 0.00026 20.8 0.0 0.00045 20.0 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AMMECR1 PF01871.17 EWM24756.1 - 1.4e-42 145.1 0.0 1.7e-42 144.8 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 Conotoxin PF02950.17 EWM24757.1 - 0.11 13.5 2.6 4.5 8.4 1.4 2.8 2 0 0 2 2 2 0 Conotoxin BCMA-Tall_bind PF09257.10 EWM24757.1 - 0.76 9.9 5.5 2.1 8.5 5.5 1.7 1 0 0 1 1 1 0 BCMA, TALL-1 binding gag_pre-integrs PF13976.6 EWM24758.1 - 2.5e-06 27.3 0.0 4.6e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain MRI PF15325.6 EWM24758.1 - 0.048 14.7 4.0 0.048 14.7 4.0 2.1 1 1 1 2 2 2 0 Modulator of retrovirus infection Arrestin_N PF00339.29 EWM24759.1 - 2.3e-10 40.7 0.0 8.6e-10 38.9 0.0 1.7 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EWM24759.1 - 7.1e-05 23.3 0.0 0.00021 21.8 0.0 1.7 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Spo0M PF07070.11 EWM24759.1 - 0.00065 19.3 0.0 0.0026 17.3 0.0 1.8 1 1 0 1 1 1 1 SpoOM protein Rgp1 PF08737.10 EWM24759.1 - 0.12 11.6 0.1 4.2 6.4 0.0 2.1 2 0 0 2 2 2 0 Rgp1 Exo_endo_phos PF03372.23 EWM24760.1 - 3.4e-05 23.5 0.1 5.5e-05 22.8 0.1 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Glyco_trans_4_2 PF13477.6 EWM24760.1 - 0.097 12.7 0.0 1.3 9.1 0.0 2.4 3 0 0 3 3 3 0 Glycosyl transferase 4-like RRM_1 PF00076.22 EWM24762.1 - 6.3e-20 70.8 0.0 9.1e-20 70.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EWM24762.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif AP2 PF00847.20 EWM24765.1 - 6e-06 26.4 1.0 9.4e-06 25.8 1.0 1.3 1 0 0 1 1 1 1 AP2 domain UQ_con PF00179.26 EWM24769.1 - 9.2e-16 57.8 0.0 1.5e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EWM24769.1 - 0.027 14.7 0.0 0.049 13.9 0.0 1.4 1 0 0 1 1 1 0 RWD domain tRNA_int_endo PF01974.17 EWM24772.1 - 6.9e-15 54.9 0.0 1.2e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain DNA_processg_A PF02481.15 EWM24772.1 - 0.097 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 DNA recombination-mediator protein A TFIIS_M PF07500.14 EWM24773.1 - 0.00033 21.1 0.2 0.00062 20.2 0.0 1.6 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain Acyl_transf_3 PF01757.22 EWM24774.1 - 1.4e-13 50.6 28.2 2.1e-13 50.1 28.2 1.2 1 0 0 1 1 1 1 Acyltransferase family Thioredoxin_8 PF13905.6 EWM24778.1 - 1.6e-09 38.0 0.0 2.3e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EWM24778.1 - 0.002 18.0 0.0 0.0028 17.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 EWM24778.1 - 0.012 15.0 0.2 0.16 11.3 0.2 2.0 1 1 0 1 1 1 0 OST3 / OST6 family, transporter family Nop25 PF09805.9 EWM24780.1 - 2.8e-14 53.7 5.9 2.8e-14 53.7 5.9 2.2 1 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) DUF3086 PF11285.8 EWM24780.1 - 0.0076 15.4 0.1 0.012 14.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3086) DUF1115 PF06544.12 EWM24781.1 - 8.9e-37 126.4 0.0 1.6e-36 125.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) PRP3 PF08572.10 EWM24781.1 - 1e-20 74.5 0.9 1e-20 74.5 0.9 1.6 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF812 PF05667.11 EWM24781.1 - 0.0076 15.2 0.6 0.0084 15.1 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) GTP_EFTU PF00009.27 EWM24782.1 - 0.012 15.2 0.0 0.012 15.1 0.0 1.0 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF1857 PF08982.11 EWM24782.1 - 0.096 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1857) WD40 PF00400.32 EWM24783.1 - 1.3e-16 60.6 0.0 6.4e-08 33.1 0.1 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM24783.1 - 0.0033 17.7 0.0 0.63 10.4 0.0 2.4 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EWM24783.1 - 0.014 15.2 0.0 0.02 14.8 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Skp1 PF01466.19 EWM24786.1 - 0.0019 18.3 0.0 0.003 17.7 0.0 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain BTB PF00651.31 EWM24786.1 - 0.11 12.8 0.0 0.77 10.0 0.0 2.2 1 1 0 1 1 1 0 BTB/POZ domain Lipoprotein_20 PF13942.6 EWM24790.1 - 7.5e-05 22.7 0.4 7.5e-05 22.7 0.4 2.3 2 0 0 2 2 2 1 YfhG lipoprotein UPF0242 PF06785.11 EWM24790.1 - 0.0017 18.5 5.9 0.0028 17.8 5.9 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Uso1_p115_C PF04871.13 EWM24790.1 - 0.0023 18.3 11.4 0.0023 18.3 11.4 1.9 2 1 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region TPR_MLP1_2 PF07926.12 EWM24790.1 - 0.026 14.6 9.4 0.082 13.0 9.4 2.0 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Tnp_22_trimer PF17489.2 EWM24790.1 - 0.028 14.4 10.1 2.5 8.2 1.1 3.7 3 0 0 3 3 3 0 L1 transposable element trimerization domain KASH_CCD PF14662.6 EWM24790.1 - 0.04 13.8 10.7 0.2 11.5 10.5 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF724 PF05266.14 EWM24790.1 - 0.078 12.8 7.1 0.028 14.2 4.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Spectrin PF00435.21 EWM24790.1 - 0.12 12.8 11.6 1.7 9.1 1.4 2.8 2 1 1 3 3 3 0 Spectrin repeat Exonuc_VII_L PF02601.15 EWM24790.1 - 0.25 10.9 5.6 0.33 10.5 5.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit BLOC1_2 PF10046.9 EWM24790.1 - 0.52 10.6 3.6 0.98 9.8 2.6 2.0 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4407 PF14362.6 EWM24790.1 - 0.7 9.2 12.7 1.1 8.6 12.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 EWM24790.1 - 1.1 9.7 2.7 8.7 6.9 0.8 3.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 EWM24790.1 - 4.3 6.1 13.0 28 3.5 12.9 2.2 1 1 0 1 1 1 0 Spc7 kinetochore protein FUSC PF04632.12 EWM24790.1 - 6.4 5.2 20.8 24 3.3 3.9 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family Med9 PF07544.13 EWM24790.1 - 8.9 6.5 8.2 8.3 6.6 0.2 2.9 1 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Csm1_N PF18504.1 EWM24791.1 - 0.022 15.1 1.3 0.022 15.1 1.3 2.4 2 2 0 2 2 2 0 Csm1 N-terminal domain MAD PF05557.13 EWM24791.1 - 0.47 8.8 17.1 0.74 8.1 17.1 1.3 1 1 0 1 1 1 0 Mitotic checkpoint protein Rab5-bind PF09311.11 EWM24791.1 - 1.4 8.3 15.4 0.087 12.2 5.3 2.1 1 1 0 2 2 2 0 Rabaptin-like protein BBS1 PF14779.6 EWM24791.1 - 2.7 7.4 5.1 0.68 9.3 2.1 1.4 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 1 CREPT PF16566.5 EWM24791.1 - 3.3 7.9 11.8 7.7 6.7 2.8 2.6 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour GldM_N PF12081.8 EWM24791.1 - 3.4 7.7 10.7 0.97 9.5 1.5 2.1 1 1 1 2 2 2 0 GldM N-terminal domain IMUP PF15761.5 EWM24795.1 - 0.029 15.1 5.7 0.041 14.6 5.7 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 EWM24795.1 - 2.5 7.7 7.2 3.1 7.4 7.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Homeobox_KN PF05920.11 EWM24796.1 - 8.6e-08 32.0 0.4 1.3e-07 31.4 0.4 1.3 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EWM24796.1 - 0.075 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Homeodomain PT PF04886.12 EWM24799.1 - 1.3e-13 50.2 45.8 0.15 11.6 45.8 2.7 1 1 0 1 1 1 1 PT repeat BNR PF02012.20 EWM24799.1 - 0.66 10.2 3.2 1.1 9.5 1.0 2.6 3 0 0 3 3 3 0 BNR/Asp-box repeat Methyltransf_25 PF13649.6 EWM24800.1 - 7.2e-07 29.8 0.0 0.015 16.0 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 EWM24800.1 - 5.4e-06 26.3 0.0 8.1e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EWM24800.1 - 1e-05 26.2 0.0 0.037 14.8 0.0 2.5 2 1 0 2 2 2 2 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EWM24800.1 - 0.045 12.9 0.0 0.15 11.3 0.0 1.7 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Retrotran_gag_2 PF14223.6 EWM24802.1 - 2.8e-08 33.5 0.1 4.5e-08 32.9 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF1759 PF03564.15 EWM24802.1 - 0.0027 17.7 0.2 0.018 15.0 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) Keratin_2_head PF16208.5 EWM24802.1 - 0.083 13.0 9.6 0.22 11.7 9.6 1.7 1 0 0 1 1 1 0 Keratin type II head SRP68 PF16969.5 EWM24805.1 - 6.8e-23 81.5 2.1 8.4e-23 81.2 2.1 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 SRP68 PF16969.5 EWM24809.1 - 3.3e-63 214.5 0.1 3.9e-63 214.3 0.1 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 Retrotran_gag_2 PF14223.6 EWM24811.1 - 0.0026 17.4 0.1 0.0036 17.0 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF1759 PF03564.15 EWM24811.1 - 0.013 15.5 0.3 0.13 12.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) RVT_2 PF07727.14 EWM24812.1 - 3.9e-10 39.8 0.1 1.2e-09 38.2 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DEDD_Tnp_IS110 PF01548.17 EWM24812.1 - 0.049 13.5 0.1 0.092 12.6 0.1 1.4 1 0 0 1 1 1 0 Transposase DEDD_Tnp_IS110 PF01548.17 EWM24814.1 - 0.03 14.2 0.1 0.051 13.5 0.1 1.4 1 0 0 1 1 1 0 Transposase DUF4232 PF14016.6 EWM24814.1 - 0.16 12.1 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) rve PF00665.26 EWM24815.1 - 1.2e-10 41.6 0.0 1.9e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain RVT_2 PF07727.14 EWM24818.1 - 1.1e-31 110.3 0.0 3.7e-31 108.6 0.0 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.14 EWM24819.1 - 2.2e-57 194.5 0.0 3e-57 194.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RXT2_N PF08595.11 EWM24820.1 - 0.71 9.9 5.1 0.14 12.1 1.6 1.6 2 0 0 2 2 2 0 RXT2-like, N-terminal Nop14 PF04147.12 EWM24820.1 - 1.3 7.2 6.0 1.4 7.0 6.0 1.2 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 EWM24820.1 - 1.5 6.8 9.3 1.7 6.6 9.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 EWM24820.1 - 1.5 8.0 8.3 2.8 7.2 8.3 1.4 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 EWM24820.1 - 4.7 5.4 5.7 5.7 5.1 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF21 PF01595.20 EWM24822.1 - 2.1e-15 56.8 0.1 2.9e-15 56.4 0.1 1.1 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain DUF21 PF01595.20 EWM24823.1 - 3.1e-15 56.3 0.1 4.4e-15 55.8 0.1 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain HSP70 PF00012.20 EWM24828.1 - 5.4e-27 94.2 0.0 5.1e-26 91.0 0.0 1.9 1 1 0 1 1 1 1 Hsp70 protein TMEM51 PF15345.6 EWM24830.1 - 0.022 14.6 0.0 0.022 14.6 0.0 4.4 3 2 0 3 3 3 0 Transmembrane protein 51 HIG_1_N PF04588.13 EWM24830.1 - 0.18 12.1 1.4 0.34 11.2 0.1 1.9 2 0 0 2 2 2 0 Hypoxia induced protein conserved region FixS PF03597.15 EWM24830.1 - 0.4 10.4 0.1 0.4 10.4 0.1 2.0 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type Arf PF00025.21 EWM24831.1 - 1.4e-67 226.5 0.0 1.7e-67 226.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EWM24831.1 - 2.1e-14 53.8 0.0 2.9e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EWM24831.1 - 1e-12 48.0 0.0 1.3e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EWM24831.1 - 6.6e-11 42.0 0.2 1e-07 31.5 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EWM24831.1 - 3e-09 36.6 0.0 3.7e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EWM24831.1 - 2.2e-08 33.8 0.0 2.7e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EWM24831.1 - 0.00018 21.5 0.0 0.00028 20.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Suppressor_APC PF11414.8 EWM24831.1 - 0.1 12.7 0.0 0.69 10.0 0.0 2.2 3 0 0 3 3 3 0 Adenomatous polyposis coli tumour suppressor protein AAA_16 PF13191.6 EWM24831.1 - 0.13 12.6 0.6 2.7 8.3 0.4 2.3 2 0 0 2 2 2 0 AAA ATPase domain Arf PF00025.21 EWM24832.1 - 1.4e-56 190.7 0.0 1.7e-56 190.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EWM24832.1 - 1.5e-14 54.2 0.0 2.2e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EWM24832.1 - 7.6e-13 48.4 0.0 9.7e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EWM24832.1 - 5e-11 42.4 0.2 8.1e-08 31.8 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EWM24832.1 - 2.2e-09 37.0 0.0 2.7e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EWM24832.1 - 1.7e-08 34.1 0.0 2.1e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EWM24832.1 - 8.5e-05 22.6 0.0 0.00022 21.3 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EWM24832.1 - 0.11 12.9 0.5 2.3 8.6 0.4 2.2 2 0 0 2 2 2 0 AAA ATPase domain DUF561 PF04481.12 EWM24833.1 - 7.3e-74 248.0 0.0 9.5e-74 247.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF561) PAP2_3 PF14378.6 EWM24833.1 - 0.034 13.9 0.2 0.071 12.8 0.2 1.5 1 0 0 1 1 1 0 PAP2 superfamily Arf PF00025.21 EWM24834.1 - 2e-67 226.0 0.0 2.5e-67 225.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EWM24834.1 - 1.6e-15 57.4 0.0 2.1e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EWM24834.1 - 9.8e-15 54.5 0.0 1.2e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EWM24834.1 - 3.4e-12 46.2 0.0 4.3e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EWM24834.1 - 4.9e-11 42.4 1.6 1.1e-07 31.4 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EWM24834.1 - 2.8e-10 39.9 0.0 3.6e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EWM24834.1 - 6.5e-05 23.0 0.0 9.5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EWM24834.1 - 0.0058 17.0 1.4 0.63 10.4 0.2 2.3 2 0 0 2 2 2 1 AAA ATPase domain PurL_C PF16904.5 EWM24834.1 - 0.065 13.5 0.0 0.13 12.5 0.0 1.5 1 1 0 1 1 1 0 Phosphoribosylformylglycinamidine synthase II C-terminus AAA_22 PF13401.6 EWM24834.1 - 0.086 13.1 0.2 0.58 10.4 0.2 2.0 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 EWM24834.1 - 0.12 11.9 0.0 0.35 10.4 0.0 1.6 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain DLIC PF05783.11 EWM24834.1 - 0.13 11.0 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) NACHT PF05729.12 EWM24834.1 - 0.13 12.1 0.3 0.36 10.7 0.1 1.7 2 0 0 2 2 2 0 NACHT domain 6PF2K PF01591.18 EWM24834.1 - 0.17 11.2 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase PAP2 PF01569.21 EWM24835.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 PAP2 superfamily DUF2960 PF11173.8 EWM24838.1 - 0.013 16.0 0.8 0.044 14.2 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2960) UQ_con PF00179.26 EWM24840.1 - 1e-46 158.1 0.0 1.2e-46 157.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EWM24840.1 - 0.0031 17.2 0.0 0.0039 16.9 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EWM24840.1 - 0.013 15.8 0.0 0.014 15.7 0.0 1.2 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 EWM24840.1 - 0.063 13.1 0.0 0.089 12.7 0.0 1.3 1 0 0 1 1 1 0 UEV domain LCM PF04072.14 EWM24841.1 - 2.7e-06 27.5 0.3 0.0001 22.3 0.0 2.2 2 0 0 2 2 2 2 Leucine carboxyl methyltransferase CD36 PF01130.21 EWM24842.1 - 6.6e-22 77.7 0.0 9e-22 77.2 0.0 1.1 1 0 0 1 1 1 1 CD36 family DUF4386 PF14329.6 EWM24842.1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4386) CD36 PF01130.21 EWM24843.1 - 2.4e-19 69.2 0.0 4.7e-18 65.0 0.0 2.1 1 1 0 1 1 1 1 CD36 family NolV PF06635.12 EWM24844.1 - 0.69 9.3 3.3 0.49 9.7 0.8 1.8 2 0 0 2 2 2 0 Nodulation protein NolV DUF724 PF05266.14 EWM24844.1 - 2.3 8.0 6.8 3.3 7.5 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) SRR1 PF07985.12 EWM24845.1 - 1.1e-10 41.3 1.7 6.9e-10 38.8 1.7 2.1 1 1 0 1 1 1 1 SRR1 Zn_clus PF00172.18 EWM24849.1 - 0.0005 20.1 14.8 0.00091 19.3 14.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DnaA_N PF11638.8 EWM24850.1 - 0.058 13.1 0.3 0.12 12.2 0.2 1.6 1 1 1 2 2 2 0 DnaA N-terminal domain Myc_N PF01056.18 EWM24853.1 - 0.028 14.3 1.2 0.036 14.0 1.2 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Ribosomal_60s PF00428.19 EWM24853.1 - 0.046 14.3 2.9 0.08 13.5 2.9 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein CDC45 PF02724.14 EWM24853.1 - 0.25 9.6 1.2 0.28 9.4 1.2 1.0 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 EWM24853.1 - 0.41 10.3 2.8 0.6 9.8 2.8 1.3 1 0 0 1 1 1 0 FAM176 family DUF4661 PF15576.6 EWM24853.1 - 0.74 9.7 3.7 0.99 9.3 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) DNA_pol_phi PF04931.13 EWM24853.1 - 2.3 6.2 3.7 2.8 5.9 3.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 EWM24853.1 - 3.8 8.0 6.6 5.9 7.3 6.6 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 EWM24853.1 - 4.1 6.6 5.5 6.4 6.0 5.5 1.2 1 0 0 1 1 1 0 NOA36 protein SAP PF02037.27 EWM24856.1 - 0.00055 19.6 0.0 0.00083 19.0 0.0 1.3 1 0 0 1 1 1 1 SAP domain LETM1 PF07766.13 EWM24856.1 - 0.0032 16.9 0.2 0.0052 16.2 0.2 1.3 1 0 0 1 1 1 1 LETM1-like protein dsRBD2 PF17842.1 EWM24856.1 - 0.008 16.4 0.1 0.011 16.0 0.1 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding domain 2 Rho_N PF07498.12 EWM24856.1 - 0.0084 16.0 0.0 0.011 15.6 0.0 1.1 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain Snf7 PF03357.21 EWM24858.1 - 1.2e-43 148.7 5.5 1.5e-43 148.4 5.5 1.0 1 0 0 1 1 1 1 Snf7 Prefoldin_2 PF01920.20 EWM24858.1 - 0.00019 21.3 1.4 4.4 7.3 0.4 3.3 2 1 0 3 3 3 3 Prefoldin subunit DASH_Dam1 PF08653.10 EWM24858.1 - 0.0088 15.8 1.9 0.55 10.1 0.2 3.1 3 0 0 3 3 3 1 DASH complex subunit Dam1 NPV_P10 PF05531.12 EWM24858.1 - 0.067 13.7 8.4 0.58 10.7 2.4 3.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein ABC_tran_CTD PF16326.5 EWM24858.1 - 0.11 12.7 4.4 2.7 8.3 1.4 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF848 PF05852.11 EWM24858.1 - 0.35 11.0 4.3 0.28 11.3 2.6 1.7 1 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Rx_N PF18052.1 EWM24858.1 - 0.78 10.0 6.3 1 9.6 0.1 2.7 1 1 1 3 3 3 0 Rx N-terminal domain BLOC1_2 PF10046.9 EWM24858.1 - 0.8 10.1 5.1 2 8.8 0.3 2.9 1 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Caskin-tail PF16632.5 EWM24858.1 - 2.6 8.5 9.8 0.28 11.6 4.9 1.9 2 1 0 2 2 2 0 C-terminal region of Caskin Rad60-SLD PF11976.8 EWM24860.1 - 7.9e-13 48.0 0.0 2.7e-09 36.7 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EWM24860.1 - 1e-08 34.8 0.0 1.8e-06 27.6 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin family PBP1_TM PF14812.6 EWM24860.1 - 1.7 9.1 5.8 0.52 10.7 0.7 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Globin PF00042.22 EWM24861.1 - 2.8e-10 40.7 0.0 9.4e-10 39.0 0.0 1.8 2 0 0 2 2 2 1 Globin FAD_binding_6 PF00970.24 EWM24861.1 - 6.1e-07 29.7 0.0 0.03 14.6 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase FAD-binding domain Lactamase_B_2 PF12706.7 EWM24862.1 - 7.8e-06 25.5 0.8 3.1e-05 23.6 0.4 2.2 3 0 0 3 3 3 1 Beta-lactamase superfamily domain AtuA PF07287.11 EWM24862.1 - 0.025 13.3 0.1 0.037 12.7 0.1 1.2 1 0 0 1 1 1 0 Acyclic terpene utilisation family protein AtuA Ribosomal_L50 PF10501.9 EWM24862.1 - 0.089 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal subunit 39S Lactamase_B_2 PF12706.7 EWM24863.1 - 7.4e-06 25.6 0.6 2.1e-05 24.1 0.4 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain AtuA PF07287.11 EWM24863.1 - 0.019 13.7 0.1 0.029 13.1 0.1 1.2 1 0 0 1 1 1 0 Acyclic terpene utilisation family protein AtuA Ribosomal_L50 PF10501.9 EWM24863.1 - 0.079 13.1 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal subunit 39S TolA_bind_tri PF16331.5 EWM24867.1 - 0.0048 17.0 0.9 0.037 14.1 0.2 2.0 2 0 0 2 2 2 1 TolA binding protein trimerisation GOLGA2L5 PF15070.6 EWM24867.1 - 0.018 13.7 2.4 0.021 13.5 2.4 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Lipase_chap PF03280.14 EWM24867.1 - 0.021 14.8 1.2 0.023 14.6 1.2 1.0 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein BRE1 PF08647.11 EWM24867.1 - 0.029 14.4 3.6 0.035 14.2 3.6 1.1 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Nup54 PF13874.6 EWM24867.1 - 0.032 14.3 1.4 0.04 14.0 1.4 1.1 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 PI3K_P85_iSH2 PF16454.5 EWM24867.1 - 0.088 12.4 1.9 0.13 11.8 0.7 1.6 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain HIP1_clath_bdg PF16515.5 EWM24867.1 - 0.14 12.8 5.8 0.23 12.1 5.8 1.4 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DivIC PF04977.15 EWM24867.1 - 7 6.5 7.3 1.8 8.4 0.9 2.4 1 1 1 3 3 3 0 Septum formation initiator LisH_TPL PF17814.1 EWM24867.1 - 9.6 6.0 6.5 2.8 7.7 1.4 2.5 3 0 0 3 3 3 0 LisH-like dimerisation domain Nop53 PF07767.11 EWM24868.1 - 4.1e-40 138.4 27.9 5.4e-40 138.0 27.9 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Spt5_N PF11942.8 EWM24868.1 - 0.66 11.0 19.4 0.045 14.7 10.5 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DICT PF10069.9 EWM24870.1 - 0.12 12.2 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Sensory domain in DIguanylate Cyclases and Two-component system Peptidase_M16_C PF05193.21 EWM24872.1 - 2.1e-07 31.1 0.0 2.7e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16_M PF16187.5 EWM24872.1 - 2.5e-06 27.0 0.0 3.9e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 HTH_53 PF18606.1 EWM24872.1 - 0.043 13.5 0.0 0.09 12.5 0.0 1.6 1 0 0 1 1 1 0 Zap helix turn helix N-terminal domain Peptidase_M16 PF00675.20 EWM24874.1 - 6.6e-42 143.0 0.0 7.9e-42 142.7 0.0 1.1 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Methyltransf_21 PF05050.12 EWM24875.1 - 1.7e-06 28.1 0.0 2.7e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_23 PF13489.6 EWM24875.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain DoxX_2 PF13564.6 EWM24878.1 - 0.053 13.6 0.3 0.076 13.1 0.3 1.3 1 0 0 1 1 1 0 DoxX-like family Nsp1_C PF05064.13 EWM24880.1 - 0.023 14.5 0.0 0.045 13.6 0.0 1.5 1 1 0 1 1 1 0 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 EWM24880.1 - 9.9 7.1 83.8 0.98 10.3 17.9 4.2 1 1 3 4 4 4 0 Nucleoporin FG repeat region DUF393 PF04134.12 EWM24881.1 - 6.3e-22 79.0 0.0 1.1e-21 78.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF393 adh_short_C2 PF13561.6 EWM24882.1 - 4.9e-59 199.7 0.0 5.9e-59 199.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EWM24882.1 - 1.2e-45 155.4 0.1 1.5e-45 155.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EWM24882.1 - 9e-10 38.7 0.3 1.3e-09 38.2 0.3 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EWM24882.1 - 0.01 15.0 0.1 0.014 14.6 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1776 PF08643.10 EWM24882.1 - 0.034 13.5 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Cu_bind_CorA PF18252.1 EWM24882.1 - 0.067 12.8 0.0 0.15 11.7 0.0 1.5 2 0 0 2 2 2 0 Copper(I)-binding protein CorA Adenine_deam_C PF13382.6 EWM24882.1 - 0.094 12.1 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Adenine deaminase C-terminal domain Epimerase PF01370.21 EWM24882.1 - 0.12 11.8 0.3 0.31 10.5 0.3 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF2737 PF10930.8 EWM24883.1 - 0.01 15.4 0.2 0.017 14.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2737) E1-E2_ATPase PF00122.20 EWM24884.1 - 4.9e-38 130.4 0.0 4.9e-38 130.4 0.0 3.6 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 EWM24884.1 - 7.4e-15 55.8 1.4 2.1e-09 38.0 0.1 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HMA PF00403.26 EWM24884.1 - 0.03 14.8 0.3 0.068 13.6 0.3 1.6 1 0 0 1 1 1 0 Heavy-metal-associated domain GKAP PF03359.13 EWM24884.1 - 0.17 11.4 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein Hamartin PF04388.12 EWM24885.1 - 0.55 8.8 4.5 0.59 8.7 4.5 1.1 1 0 0 1 1 1 0 Hamartin protein DUF1180 PF06679.12 EWM24885.1 - 2.2 8.7 4.8 0.58 10.6 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Pkinase PF00069.25 EWM24886.1 - 1.1e-60 205.3 0.0 5.3e-59 199.7 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM24886.1 - 3.3e-31 108.5 0.0 1.7e-30 106.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EWM24886.1 - 3.1e-05 23.4 0.0 4.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DLH PF01738.18 EWM24886.1 - 0.037 13.6 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Haspin_kinase PF12330.8 EWM24886.1 - 0.077 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_C PF00433.24 EWM24886.1 - 0.093 13.4 1.5 0.32 11.7 0.3 2.6 2 0 0 2 2 2 0 Protein kinase C terminal domain TMA7 PF09072.10 EWM24886.1 - 0.12 13.2 0.2 0.32 11.9 0.2 1.7 1 0 0 1 1 1 0 Translation machinery associated TMA7 UPRTase PF14681.6 EWM24887.1 - 6.3e-66 221.8 0.0 8e-66 221.4 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EWM24887.1 - 0.0055 16.2 0.0 0.0085 15.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DOT1 PF08123.13 EWM24888.1 - 7.7e-11 41.9 0.0 1.4e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 PCMT PF01135.19 EWM24888.1 - 0.0088 15.8 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 EWM24888.1 - 0.012 16.2 0.0 0.026 15.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EWM24888.1 - 0.029 15.0 0.0 0.059 14.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 EWM24888.1 - 0.05 13.1 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PITH PF06201.13 EWM24889.1 - 5.1e-33 114.4 0.1 5.9e-33 114.2 0.1 1.0 1 0 0 1 1 1 1 PITH domain Sad1_UNC PF07738.13 EWM24889.1 - 0.078 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal tRNA_synt_1c_R2 PF04557.15 EWM24890.1 - 0.054 14.4 3.8 0.091 13.7 3.8 1.3 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Shal-type PF11601.8 EWM24891.1 - 0.081 12.5 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 Shal-type voltage-gated potassium channels, N-terminal Solute_trans_a PF03619.16 EWM24892.1 - 1.5e-28 100.1 0.9 2e-28 99.7 0.9 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha T4SS_CagC PF16943.5 EWM24892.1 - 0.00041 20.5 0.0 0.19 11.9 0.0 2.3 2 0 0 2 2 2 2 Cag pathogenicity island, type IV secretory system AA_permease_2 PF13520.6 EWM24892.1 - 2.1 7.1 5.7 0.18 10.6 0.5 1.7 2 0 0 2 2 2 0 Amino acid permease Lung_7-TM_R PF06814.13 EWM24893.1 - 6.5e-56 189.7 8.5 8.6e-56 189.3 8.5 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 EWM24893.1 - 2.6e-09 36.9 7.4 4.8e-09 36.0 7.4 1.4 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 EWM24894.1 - 6.9e-56 189.7 8.5 8.9e-56 189.3 8.5 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 EWM24894.1 - 3.2e-09 36.6 7.4 5e-09 36.0 7.4 1.3 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain DUF1997 PF09366.10 EWM24895.1 - 2.1e-05 24.7 0.0 3.2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1997) DUF2883 PF11097.8 EWM24895.1 - 0.23 11.6 0.3 32 4.7 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2883) adh_short PF00106.25 EWM24896.1 - 1.4e-35 122.6 0.7 2.5e-35 121.7 0.7 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EWM24896.1 - 1.3e-33 116.5 0.9 2.4e-33 115.7 0.9 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM24896.1 - 2.5e-08 34.1 3.0 5.8e-08 32.8 3.0 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EWM24896.1 - 0.011 15.2 0.2 0.033 13.6 0.1 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family AAA PF00004.29 EWM24897.1 - 1.6e-44 151.5 0.7 7.4e-44 149.4 0.0 2.3 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EWM24897.1 - 2.2e-10 40.3 0.1 1.4e-09 37.8 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 EWM24897.1 - 1.1e-08 35.1 0.1 3.8e-08 33.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EWM24897.1 - 3.2e-08 33.9 1.1 1.8e-07 31.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_3 PF17862.1 EWM24897.1 - 8.6e-06 25.5 0.3 2.4e-05 24.1 0.3 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EWM24897.1 - 2.9e-05 24.5 0.2 0.0046 17.4 0.0 2.6 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EWM24897.1 - 0.00018 21.3 0.0 0.00059 19.6 0.0 1.9 2 1 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EWM24897.1 - 0.00026 20.3 0.0 0.0027 17.0 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain DUF815 PF05673.13 EWM24897.1 - 0.00056 19.1 0.0 0.0013 17.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 EWM24897.1 - 0.0007 19.8 0.0 0.0036 17.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EWM24897.1 - 0.00082 19.9 0.0 0.004 17.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EWM24897.1 - 0.00087 18.7 0.1 0.002 17.5 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EWM24897.1 - 0.0017 18.2 0.1 0.0069 16.1 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein RNA_helicase PF00910.22 EWM24897.1 - 0.0021 18.4 0.0 0.0099 16.3 0.0 2.2 2 0 0 2 2 1 1 RNA helicase AAA_7 PF12775.7 EWM24897.1 - 0.0039 16.7 0.2 0.021 14.4 0.2 2.1 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 EWM24897.1 - 0.0041 17.4 6.4 0.13 12.6 0.1 3.5 3 1 1 4 4 3 1 AAA domain NTPase_1 PF03266.15 EWM24897.1 - 0.0044 17.0 0.4 0.069 13.1 0.0 2.7 3 0 0 3 3 3 1 NTPase AAA_28 PF13521.6 EWM24897.1 - 0.0058 16.9 0.1 0.02 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EWM24897.1 - 0.0067 16.1 0.6 0.15 11.8 0.0 2.9 3 1 0 3 3 3 1 Sigma-54 interaction domain TsaE PF02367.17 EWM24897.1 - 0.011 15.8 0.0 0.027 14.5 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EWM24897.1 - 0.012 15.3 0.4 0.012 15.3 0.4 2.1 2 1 0 2 2 1 0 AAA domain DUF3363 PF11843.8 EWM24897.1 - 0.013 14.4 0.8 0.018 14.0 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3363) AAA_23 PF13476.6 EWM24897.1 - 0.017 15.6 2.0 4.5 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EWM24897.1 - 0.019 15.0 0.1 0.071 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 EWM24897.1 - 0.02 14.0 0.0 0.038 13.1 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 IPT PF01745.16 EWM24897.1 - 0.022 14.2 0.1 0.085 12.2 0.1 2.0 2 0 0 2 2 2 0 Isopentenyl transferase AAA_3 PF07726.11 EWM24897.1 - 0.022 14.6 0.1 0.23 11.3 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EWM24897.1 - 0.044 13.7 0.1 0.33 10.8 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 EWM24897.1 - 0.055 13.2 1.5 0.074 12.8 0.2 2.0 2 1 0 2 2 1 0 AAA domain AAA_11 PF13086.6 EWM24897.1 - 0.067 13.0 0.1 0.32 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 EWM24897.1 - 0.071 12.5 0.0 3.8 6.9 0.0 2.5 2 0 0 2 2 2 0 Bacterial TniB protein AAA_17 PF13207.6 EWM24897.1 - 0.09 13.2 0.2 0.25 11.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain ATPase PF06745.13 EWM24897.1 - 0.1 11.9 2.5 0.41 10.0 0.0 2.7 3 0 0 3 3 3 0 KaiC HIP1_clath_bdg PF16515.5 EWM24897.1 - 0.27 11.9 6.6 0.66 10.6 4.1 2.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 GvpG PF05120.12 EWM24897.1 - 1.6 8.8 5.8 0.97 9.5 3.0 2.0 2 0 0 2 2 2 0 Gas vesicle protein G AAA_25 PF13481.6 EWM24897.1 - 2 7.9 5.5 0.92 9.0 0.3 2.6 2 1 0 3 3 3 0 AAA domain GrpE PF01025.19 EWM24897.1 - 2.9 7.5 8.1 0.79 9.4 2.5 2.4 3 0 0 3 3 2 0 GrpE AAA PF00004.29 EWM24898.1 - 1.3e-44 151.8 0.6 6.5e-44 149.6 0.0 2.3 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EWM24898.1 - 1.9e-10 40.5 0.1 1.3e-09 37.9 0.0 2.3 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 EWM24898.1 - 1e-08 35.3 0.1 3.5e-08 33.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EWM24898.1 - 2.5e-08 34.2 1.0 1.6e-07 31.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_3 PF17862.1 EWM24898.1 - 7.6e-06 25.6 0.3 2.2e-05 24.2 0.3 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EWM24898.1 - 2.6e-05 24.7 0.2 0.0042 17.5 0.0 2.6 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EWM24898.1 - 0.00016 21.5 0.0 0.00053 19.8 0.0 1.9 2 1 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EWM24898.1 - 0.00022 20.6 0.0 0.0025 17.1 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain DUF815 PF05673.13 EWM24898.1 - 0.00051 19.3 0.0 0.0011 18.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 EWM24898.1 - 0.00069 20.2 0.0 0.0035 17.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EWM24898.1 - 0.00072 19.7 0.2 0.0058 16.8 0.1 2.2 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EWM24898.1 - 0.00079 18.9 0.1 0.0019 17.7 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EWM24898.1 - 0.0014 18.4 0.1 0.0063 16.3 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.6 EWM24898.1 - 0.0024 18.2 6.0 0.12 12.7 0.1 3.5 3 1 1 4 4 3 1 AAA domain RNA_helicase PF00910.22 EWM24898.1 - 0.0028 18.0 0.0 0.0089 16.4 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_7 PF12775.7 EWM24898.1 - 0.0034 16.9 0.1 0.019 14.5 0.1 2.1 1 1 0 1 1 1 1 P-loop containing dynein motor region NTPase_1 PF03266.15 EWM24898.1 - 0.0037 17.2 0.4 0.061 13.2 0.0 2.7 3 0 0 3 3 3 1 NTPase AAA_28 PF13521.6 EWM24898.1 - 0.0052 17.0 0.1 0.018 15.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EWM24898.1 - 0.0054 16.4 0.6 0.13 11.9 0.0 2.9 3 1 0 3 3 3 1 Sigma-54 interaction domain TsaE PF02367.17 EWM24898.1 - 0.0095 15.9 0.0 0.024 14.6 0.0 1.7 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EWM24898.1 - 0.011 15.4 0.4 0.011 15.4 0.4 2.1 2 1 0 2 2 2 0 AAA domain DUF3363 PF11843.8 EWM24898.1 - 0.012 14.6 0.8 0.016 14.2 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3363) AAA_23 PF13476.6 EWM24898.1 - 0.014 15.9 2.0 4.1 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EWM24898.1 - 0.016 15.2 0.1 0.063 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 EWM24898.1 - 0.018 14.1 0.0 0.035 13.2 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 IPT PF01745.16 EWM24898.1 - 0.019 14.4 0.1 0.079 12.3 0.1 2.0 2 0 0 2 2 2 0 Isopentenyl transferase AAA_3 PF07726.11 EWM24898.1 - 0.02 14.8 0.1 0.21 11.5 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Mu-like_Pro PF10123.9 EWM24898.1 - 0.032 13.8 0.4 4.4 6.8 0.1 2.1 2 0 0 2 2 2 0 Mu-like prophage I protein NACHT PF05729.12 EWM24898.1 - 0.038 13.9 0.1 0.31 11.0 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 EWM24898.1 - 0.042 13.6 1.3 0.067 12.9 0.2 2.0 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EWM24898.1 - 0.058 13.2 0.1 0.29 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 EWM24898.1 - 0.059 12.8 0.0 3.5 7.0 0.0 2.6 2 0 0 2 2 2 0 Bacterial TniB protein ATPase PF06745.13 EWM24898.1 - 0.082 12.2 2.4 0.37 10.1 0.0 2.7 3 0 0 3 3 3 0 KaiC AAA_17 PF13207.6 EWM24898.1 - 0.083 13.3 0.3 0.23 11.9 0.0 1.9 2 0 0 2 2 1 0 AAA domain HIP1_clath_bdg PF16515.5 EWM24898.1 - 0.12 13.0 5.7 0.6 10.7 4.1 2.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 GrpE PF01025.19 EWM24898.1 - 0.49 10.0 5.8 0.72 9.5 2.5 2.4 2 0 0 2 2 2 0 GrpE GvpG PF05120.12 EWM24898.1 - 1.4 9.0 5.8 0.9 9.6 3.0 2.0 2 0 0 2 2 2 0 Gas vesicle protein G AAA_25 PF13481.6 EWM24898.1 - 1.9 8.0 5.5 0.82 9.2 0.3 2.6 2 1 0 3 3 3 0 AAA domain AAA PF00004.29 EWM24899.1 - 1.5e-44 151.6 0.8 6.2e-44 149.6 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EWM24899.1 - 1.9e-10 40.5 0.1 1.2e-09 37.9 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 EWM24899.1 - 9.4e-09 35.4 0.1 3.4e-08 33.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EWM24899.1 - 1.5e-08 34.9 1.0 1.6e-07 31.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EWM24899.1 - 2.7e-05 24.6 0.2 0.0041 17.5 0.0 2.5 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EWM24899.1 - 0.00015 21.6 0.0 0.00051 19.8 0.0 1.9 2 1 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 EWM24899.1 - 0.0005 19.3 0.0 0.0011 18.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 EWM24899.1 - 0.00069 19.0 0.1 0.0018 17.7 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EWM24899.1 - 0.00069 20.2 0.0 0.0034 17.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EWM24899.1 - 0.00075 19.7 0.2 0.0034 17.5 0.1 2.1 2 1 0 2 2 2 1 AAA domain Mu-like_Pro PF10123.9 EWM24899.1 - 0.00094 18.8 0.4 0.51 9.8 0.1 2.1 2 0 0 2 2 2 2 Mu-like prophage I protein TIP49 PF06068.13 EWM24899.1 - 0.00096 18.5 0.0 0.0024 17.2 0.0 1.7 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 EWM24899.1 - 0.0012 18.6 0.1 0.006 16.3 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.6 EWM24899.1 - 0.0024 18.1 6.2 0.11 12.7 0.1 3.5 3 1 1 4 4 3 1 AAA domain RNA_helicase PF00910.22 EWM24899.1 - 0.0029 18.0 0.0 0.0085 16.5 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_7 PF12775.7 EWM24899.1 - 0.0032 17.0 0.1 0.018 14.6 0.1 2.1 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_28 PF13521.6 EWM24899.1 - 0.0051 17.1 0.1 0.018 15.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EWM24899.1 - 0.0054 16.5 0.8 0.13 12.0 0.0 3.0 3 1 0 3 3 3 1 Sigma-54 interaction domain NTPase_1 PF03266.15 EWM24899.1 - 0.0058 16.6 0.1 0.059 13.3 0.0 2.3 2 0 0 2 2 2 1 NTPase TsaE PF02367.17 EWM24899.1 - 0.0092 16.0 0.0 0.023 14.7 0.0 1.7 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IPT PF01745.16 EWM24899.1 - 0.0094 15.4 0.1 0.077 12.4 0.1 2.2 2 0 0 2 2 2 1 Isopentenyl transferase AAA_30 PF13604.6 EWM24899.1 - 0.011 15.5 0.5 0.011 15.5 0.5 2.1 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EWM24899.1 - 0.017 15.2 0.1 0.061 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 EWM24899.1 - 0.018 14.9 0.1 0.2 11.5 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 EWM24899.1 - 0.019 14.1 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF3363 PF11843.8 EWM24899.1 - 0.022 13.7 0.8 0.032 13.2 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3363) NACHT PF05729.12 EWM24899.1 - 0.035 14.0 0.1 0.3 11.0 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 EWM24899.1 - 0.047 13.4 1.6 0.065 13.0 0.2 2.0 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EWM24899.1 - 0.054 14.0 4.1 3 8.3 0.0 2.4 2 1 0 2 2 2 0 AAA domain TniB PF05621.11 EWM24899.1 - 0.054 12.9 0.0 3.4 7.0 0.0 2.6 2 0 0 2 2 2 0 Bacterial TniB protein ATPase PF06745.13 EWM24899.1 - 0.063 12.6 2.5 0.36 10.1 0.0 2.9 3 0 0 3 3 3 0 KaiC AAA_17 PF13207.6 EWM24899.1 - 0.078 13.4 0.3 0.22 11.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain HIP1_clath_bdg PF16515.5 EWM24899.1 - 0.11 13.2 6.3 0.61 10.7 4.6 2.4 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 AAA_11 PF13086.6 EWM24899.1 - 0.13 12.0 1.8 0.24 11.2 0.1 2.2 2 1 0 2 2 2 0 AAA domain GrpE PF01025.19 EWM24899.1 - 0.46 10.1 6.4 0.57 9.8 3.1 2.2 2 0 0 2 2 2 0 GrpE AAA_25 PF13481.6 EWM24899.1 - 1.4 8.4 5.3 0.79 9.3 0.2 2.6 2 1 1 3 3 3 0 AAA domain GvpG PF05120.12 EWM24899.1 - 2.4 8.2 6.3 1.5 8.9 3.5 2.0 2 0 0 2 2 2 0 Gas vesicle protein G zf-MYND PF01753.18 EWM24900.1 - 2.9e-06 27.3 12.0 6.9e-06 26.1 12.0 1.6 1 0 0 1 1 1 1 MYND finger Flu_NS2 PF00601.19 EWM24900.1 - 0.022 15.0 0.0 0.067 13.5 0.0 1.8 1 0 0 1 1 1 0 Influenza non-structural protein (NS2) CIA30 PF08547.12 EWM24901.1 - 2.9e-34 118.4 0.0 4.2e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) NAD_binding_10 PF13460.6 EWM24901.1 - 2.7e-20 73.1 1.6 3.2e-10 40.2 0.0 3.0 2 1 0 2 2 2 2 NAD(P)H-binding NmrA PF05368.13 EWM24901.1 - 3.3e-07 30.1 0.3 1.6e-05 24.6 0.3 2.6 3 0 0 3 3 3 1 NmrA-like family DapB_N PF01113.20 EWM24901.1 - 0.0012 18.9 0.1 0.0071 16.5 0.1 2.1 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 EWM24901.1 - 0.0048 16.4 0.1 0.0086 15.6 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EWM24901.1 - 0.037 13.5 0.1 0.082 12.3 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase SGBP_B_XBD PF18329.1 EWM24901.1 - 0.059 13.3 0.0 0.099 12.6 0.0 1.3 1 0 0 1 1 1 0 Surface glycan-binding protein B xyloglucan binding domain Transferase PF02458.15 EWM24902.1 - 1.9e-22 79.5 0.0 2e-10 40.0 0.0 2.1 2 0 0 2 2 2 2 Transferase family DNA_ligase_A_N PF04675.14 EWM24904.1 - 4.3e-26 92.3 0.0 7.4e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 DNA ligase N terminus HTH_Tnp_IS1 PF12759.7 EWM24904.1 - 0.52 10.0 2.9 4.8 6.9 0.5 2.3 2 0 0 2 2 2 0 InsA C-terminal domain zf-MYND PF01753.18 EWM24905.1 - 1.2e-05 25.2 4.9 1.2e-05 25.2 4.9 2.3 2 0 0 2 2 2 1 MYND finger SET PF00856.28 EWM24905.1 - 0.00018 21.9 0.0 0.0003 21.2 0.0 1.4 1 0 0 1 1 1 1 SET domain zf-Mss51 PF13824.6 EWM24905.1 - 0.018 15.1 0.6 0.018 15.1 0.6 2.2 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Ecl1 PF12855.7 EWM24905.1 - 0.024 15.8 0.9 0.024 15.8 0.9 1.9 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins Mut7-C PF01927.16 EWM24907.1 - 1e-30 106.8 0.0 1.8e-30 105.9 0.0 1.5 1 0 0 1 1 1 1 Mut7-C RNAse domain tRNA_edit PF04073.15 EWM24907.1 - 8.1e-11 42.1 0.0 6.7e-09 35.9 0.0 2.4 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain CobT PF06213.12 EWM24907.1 - 0.0078 15.6 12.6 0.015 14.7 12.6 1.4 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT AAA_23 PF13476.6 EWM24907.1 - 0.0092 16.5 0.9 0.016 15.7 0.9 1.3 1 0 0 1 1 1 1 AAA domain NOA36 PF06524.12 EWM24907.1 - 0.016 14.5 11.2 0.03 13.7 11.2 1.4 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 EWM24907.1 - 0.028 13.9 15.1 0.047 13.1 15.1 1.3 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 EWM24907.1 - 0.056 11.6 23.5 0.087 10.9 23.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi TFIIA PF03153.13 EWM24907.1 - 0.065 13.2 5.8 0.092 12.7 5.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PTPRCAP PF15713.5 EWM24907.1 - 0.072 13.4 20.4 0.032 14.5 15.4 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Nop14 PF04147.12 EWM24907.1 - 0.13 10.4 17.3 0.19 9.9 17.3 1.1 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 EWM24907.1 - 0.16 10.4 16.5 0.24 9.8 16.5 1.2 1 0 0 1 1 1 0 Mpp10 protein DUF913 PF06025.12 EWM24907.1 - 0.3 10.0 1.8 0.42 9.5 1.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RNA_pol_3_Rpc31 PF11705.8 EWM24907.1 - 0.3 11.3 21.8 0.48 10.6 20.1 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 RR_TM4-6 PF06459.12 EWM24907.1 - 0.31 10.8 9.6 0.55 10.0 9.6 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CPSF100_C PF13299.6 EWM24907.1 - 0.39 10.9 4.1 1 9.5 4.1 1.7 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Connexin PF00029.19 EWM24907.1 - 0.87 9.3 3.0 1.5 8.5 3.0 1.3 1 0 0 1 1 1 0 Connexin BUD22 PF09073.10 EWM24907.1 - 2.2 7.6 14.8 0.052 12.9 8.1 1.7 2 0 0 2 2 2 0 BUD22 PPP4R2 PF09184.11 EWM24907.1 - 3.4 7.2 16.1 5.8 6.4 16.1 1.3 1 0 0 1 1 1 0 PPP4R2 DUF4746 PF15928.5 EWM24907.1 - 4.5 6.6 16.4 8.3 5.7 16.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Paf1 PF03985.13 EWM24907.1 - 5.9 5.8 22.4 11 5.0 22.4 1.3 1 0 0 1 1 1 0 Paf1 Wtap PF17098.5 EWM24908.1 - 3.2e-24 85.6 6.1 5.3e-24 84.9 6.1 1.4 1 0 0 1 1 1 1 WTAP/Mum2p family Leu_zip PF15294.6 EWM24908.1 - 0.008 15.7 3.5 0.012 15.2 3.5 1.3 1 0 0 1 1 1 1 Leucine zipper Dynamitin PF04912.14 EWM24908.1 - 0.021 14.1 4.0 0.035 13.4 4.0 1.4 1 0 0 1 1 1 0 Dynamitin FapA PF03961.13 EWM24908.1 - 0.29 9.7 1.5 0.43 9.1 1.5 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A CCDC106 PF15794.5 EWM24908.1 - 0.37 10.5 3.5 1.2 8.8 0.1 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 PKcGMP_CC PF16808.5 EWM24908.1 - 0.47 10.3 6.8 0.57 10.1 1.1 3.0 2 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DivIC PF04977.15 EWM24908.1 - 0.53 10.1 16.1 0.37 10.6 0.7 4.2 3 1 0 4 4 4 0 Septum formation initiator KASH_CCD PF14662.6 EWM24908.1 - 0.79 9.5 10.7 0.61 9.9 3.1 2.8 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Fez1 PF06818.15 EWM24908.1 - 0.85 10.0 7.3 2.2 8.7 7.0 1.8 1 1 1 2 2 2 0 Fez1 Atg14 PF10186.9 EWM24908.1 - 0.87 8.6 5.1 0.32 10.0 1.5 1.9 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ZapB PF06005.12 EWM24908.1 - 1.2 9.6 19.8 5.5 7.5 0.8 4.1 3 1 1 4 4 4 0 Cell division protein ZapB Lebercilin PF15619.6 EWM24908.1 - 2 8.1 13.8 7 6.3 0.1 2.9 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.11 EWM24908.1 - 2.5 6.9 8.8 2.1 7.2 6.3 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein HOOK PF05622.12 EWM24908.1 - 6.2 4.8 12.3 0.81 7.8 7.6 1.8 2 1 0 2 2 2 0 HOOK protein PRIMA1 PF16101.5 EWM24909.1 - 0.16 12.0 1.9 0.24 11.4 1.9 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Ribul_P_3_epim PF00834.19 EWM24910.1 - 6.8e-90 299.8 0.1 8e-90 299.5 0.1 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 EWM24910.1 - 4.5e-07 29.8 0.0 0.00027 20.8 0.0 2.2 2 0 0 2 2 2 2 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.21 EWM24910.1 - 0.011 15.2 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein PGM_PMM_II PF02879.16 EWM24910.1 - 0.015 15.9 0.0 7.3 7.3 0.0 2.6 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II TMP-TENI PF02581.17 EWM24910.1 - 0.1 11.9 0.1 0.3 10.4 0.0 1.8 2 0 0 2 2 2 0 Thiamine monophosphate synthase FA_desaturase PF00487.24 EWM24911.1 - 6.1e-27 95.1 18.8 6.1e-27 95.1 18.8 1.5 2 0 0 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.8 EWM24911.1 - 1.1e-07 32.1 0.1 2.3e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) CitMHS PF03600.16 EWM24911.1 - 0.13 11.5 0.1 0.19 10.9 0.1 1.2 1 0 0 1 1 1 0 Citrate transporter Thioredoxin PF00085.20 EWM24912.1 - 3.5e-19 68.7 0.0 6.4e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin PUB PF09409.10 EWM24912.1 - 6.8e-12 45.2 0.0 1.9e-11 43.7 0.0 1.8 1 0 0 1 1 1 1 PUB domain Thioredoxin_2 PF13098.6 EWM24912.1 - 0.045 14.2 0.0 0.19 12.2 0.0 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain BUD22 PF09073.10 EWM24912.1 - 0.18 11.1 58.5 0.7 9.2 58.5 2.1 1 0 0 1 1 1 0 BUD22 MGDG_synth PF06925.11 EWM24913.1 - 1.2e-30 106.8 0.0 1.7e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 Monogalactosyldiacylglycerol (MGDG) synthase Glyco_tran_28_C PF04101.16 EWM24913.1 - 2.6e-10 40.5 0.0 4.1e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glycos_transf_1 PF00534.20 EWM24913.1 - 8.3e-06 25.4 0.0 1.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EWM24913.1 - 0.0001 22.8 0.2 0.00043 20.7 0.0 2.1 3 0 0 3 3 3 1 Glycosyl transferases group 1 Epimerase_2 PF02350.19 EWM24913.1 - 0.21 10.4 0.0 0.4 9.5 0.0 1.5 1 1 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase Chloroa_b-bind PF00504.21 EWM24914.1 - 4.5e-39 134.6 0.1 5.5e-39 134.3 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein NAD_binding_8 PF13450.6 EWM24917.1 - 5e-05 23.4 0.1 0.00011 22.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EWM24917.1 - 0.0004 19.7 0.1 0.096 11.9 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain Glu_dehyd_C PF16912.5 EWM24917.1 - 0.0065 16.0 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus HI0933_like PF03486.14 EWM24917.1 - 0.0091 14.7 0.0 0.015 14.0 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 EWM24917.1 - 0.024 13.9 0.0 0.043 13.0 0.0 1.3 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EWM24917.1 - 0.024 14.2 0.7 0.035 13.7 0.7 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EWM24917.1 - 0.063 12.5 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EWM24917.1 - 0.079 12.9 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 EWM24917.1 - 0.092 13.3 0.2 0.46 11.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EWM24917.1 - 0.18 11.0 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ArfGap PF01412.18 EWM24918.1 - 1.1e-34 119.0 0.0 1.7e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ank_2 PF12796.7 EWM24918.1 - 1.6e-10 41.4 0.1 2.7e-10 40.7 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EWM24918.1 - 1e-08 35.6 0.1 1.2e-06 28.9 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EWM24918.1 - 1.2e-07 31.5 0.0 0.00028 21.1 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EWM24918.1 - 1.6e-07 31.5 0.3 6.2e-05 23.3 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 EWM24918.1 - 2.2e-07 31.0 0.2 8.5e-07 29.1 0.1 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) HCV_capsid PF01543.17 EWM24918.1 - 0.16 12.2 0.1 1 9.6 0.0 2.0 2 0 0 2 2 2 0 Hepatitis C virus capsid protein C2 PF00168.30 EWM24919.1 - 3.5e-07 30.5 0.0 5e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 C2 domain DUF4440 PF14534.6 EWM24920.1 - 1.4e-12 47.9 0.4 2e-12 47.5 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) CaMKII_AD PF08332.10 EWM24920.1 - 3.5e-11 43.3 0.0 4.8e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain SnoaL_3 PF13474.6 EWM24920.1 - 3e-09 37.2 0.1 4.6e-09 36.6 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 EWM24920.1 - 0.00027 21.1 0.5 0.00037 20.6 0.5 1.2 1 0 0 1 1 1 1 SnoaL-like domain TetR_C_15 PF17918.1 EWM24920.1 - 0.064 14.0 0.2 0.59 10.9 0.1 2.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF4440 PF14534.6 EWM24921.1 - 4.6e-12 46.3 1.4 8.2e-12 45.5 0.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4440) CaMKII_AD PF08332.10 EWM24921.1 - 1.5e-10 41.3 0.0 2.2e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain SnoaL_3 PF13474.6 EWM24921.1 - 6.6e-09 36.1 0.3 2e-08 34.5 0.1 1.9 2 0 0 2 2 2 1 SnoaL-like domain SnoaL_4 PF13577.6 EWM24921.1 - 0.00091 19.4 0.5 0.0016 18.6 0.5 1.4 1 0 0 1 1 1 1 SnoaL-like domain SKA1 PF07160.12 EWM24922.1 - 0.0005 20.0 0.0 0.0017 18.3 0.0 1.8 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 DNA_ligase_A_C PF04679.15 EWM24923.1 - 3.3e-21 75.7 0.0 5.5e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BESS PF02944.20 EWM24923.1 - 0.5 10.2 1.7 0.56 10.1 0.1 1.9 2 0 0 2 2 2 0 BESS motif DNA_ligase_A_C PF04679.15 EWM24924.1 - 4.8e-21 75.2 0.0 9.7e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA12 PF10443.9 EWM24925.1 - 0.057 12.2 0.0 0.12 11.0 0.0 1.3 1 1 0 1 1 1 0 RNA12 protein Pkinase PF00069.25 EWM24926.1 - 8e-31 107.4 0.0 5.1e-20 71.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EWM24926.1 - 4.1e-15 55.8 0.0 1.1e-09 37.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EWM24926.1 - 0.00048 20.1 0.0 0.0018 18.2 0.0 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EWM24926.1 - 0.015 14.6 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Prenyltransf PF01255.19 EWM24927.1 - 5.4e-68 228.9 0.0 6.7e-68 228.6 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Clathrin PF00637.20 EWM24928.1 - 9.8e-05 22.2 0.0 0.046 13.6 0.0 2.4 2 1 0 2 2 2 2 Region in Clathrin and VPS VPS11_C PF12451.8 EWM24929.1 - 1.1e-07 32.0 0.2 2.7e-07 30.7 0.2 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 EWM24929.1 - 0.00017 21.5 6.4 0.00027 20.9 6.4 1.3 1 0 0 1 1 1 1 Zinc-finger Ribosomal_60s PF00428.19 EWM24929.1 - 0.031 14.8 4.4 0.031 14.8 4.4 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein Ribosomal_L1 PF00687.21 EWM24932.1 - 1.1e-42 146.0 0.0 1.7e-42 145.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Serinc PF03348.15 EWM24934.1 - 8.6e-67 225.9 10.9 1.1e-66 225.6 10.9 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) CD225 PF04505.12 EWM24934.1 - 2.4 8.4 11.8 6.4 7.0 0.7 4.8 4 1 0 4 4 4 0 Interferon-induced transmembrane protein ABC_tran PF00005.27 EWM24935.1 - 2.6e-08 34.5 0.0 3.6e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EWM24935.1 - 0.00054 19.9 0.0 0.00066 19.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Peptidase_C12 PF01088.21 EWM24936.1 - 5.7e-27 94.8 0.0 2.4e-26 92.8 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Proteasome PF00227.26 EWM24937.1 - 4.9e-35 120.7 0.0 5.9e-35 120.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit UCH PF00443.29 EWM24938.1 - 3.2e-12 46.5 0.0 7.2e-12 45.3 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SRP54 PF00448.22 EWM24939.1 - 2.4e-53 180.7 0.0 4.3e-53 179.9 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 EWM24939.1 - 2.9e-28 99.6 0.0 4.2e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.19 EWM24939.1 - 5.5e-10 39.3 0.0 1.6e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 EWM24939.1 - 1.6e-07 30.6 0.1 6.6e-07 28.6 0.1 1.9 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 EWM24939.1 - 1.7e-06 28.1 0.2 0.0044 17.1 0.0 2.6 2 0 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 EWM24939.1 - 4.6e-06 26.5 0.1 1.1e-05 25.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EWM24939.1 - 2.6e-05 24.7 3.0 2.7e-05 24.6 0.0 2.5 3 1 0 3 3 3 1 AAA ATPase domain AAA_17 PF13207.6 EWM24939.1 - 7.8e-05 23.1 0.0 0.00036 21.0 0.0 2.2 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.15 EWM24939.1 - 0.00017 21.5 0.7 0.14 12.1 0.1 2.6 2 1 0 3 3 3 2 NTPase AAA_22 PF13401.6 EWM24939.1 - 0.0032 17.8 0.1 0.034 14.4 0.0 2.6 2 1 1 3 3 2 1 AAA domain Zeta_toxin PF06414.12 EWM24939.1 - 0.0048 16.2 0.0 0.01 15.1 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin MMR_HSR1 PF01926.23 EWM24939.1 - 0.0068 16.5 0.6 0.061 13.4 0.6 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase ETF PF01012.21 EWM24939.1 - 0.03 14.2 0.5 0.094 12.6 0.2 1.9 2 0 0 2 2 2 0 Electron transfer flavoprotein domain AAA PF00004.29 EWM24939.1 - 0.032 14.6 0.0 0.1 13.1 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Fer4_NifH PF00142.18 EWM24939.1 - 0.039 13.4 0.0 0.092 12.2 0.0 1.6 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_33 PF13671.6 EWM24939.1 - 0.041 14.0 0.0 0.13 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.6 EWM24939.1 - 0.085 12.8 0.0 0.19 11.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.9 EWM24939.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 RsgA_GTPase PF03193.16 EWM24939.1 - 0.15 11.9 0.2 1.8 8.4 0.0 2.5 3 0 0 3 3 3 0 RsgA GTPase 6PF2K PF01591.18 EWM24939.1 - 0.18 11.1 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Peptidase_S24 PF00717.23 EWM24942.1 - 8.4e-11 41.7 0.2 1.3e-10 41.1 0.2 1.3 1 0 0 1 1 1 1 Peptidase S24-like AMP-binding PF00501.28 EWM24944.1 - 5.1e-79 265.8 0.0 8.3e-79 265.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 EWM24944.1 - 7.9e-63 212.4 2.4 1.9e-62 211.1 2.4 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EWM24944.1 - 1.4e-50 171.7 0.1 2.8e-50 170.7 0.1 1.6 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 EWM24944.1 - 2.1e-47 162.2 0.3 3.6e-47 161.4 0.3 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EWM24944.1 - 6.7e-40 135.8 0.4 2.3e-39 134.1 0.1 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 EWM24944.1 - 3.3e-15 56.2 0.0 2.7e-06 27.6 0.0 3.6 3 0 0 3 3 3 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 EWM24944.1 - 2e-13 50.8 0.0 5.3e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 EWM24944.1 - 3.4e-11 43.0 0.0 7.9e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EWM24944.1 - 3.4e-09 36.6 0.0 6.8e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Hexapep_2 PF14602.6 EWM24944.1 - 4.7e-05 23.0 0.7 0.28 10.9 0.1 4.3 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 EWM24944.1 - 0.00023 20.8 13.5 0.051 13.3 1.5 6.2 4 2 0 4 4 4 1 Bacterial transferase hexapeptide (six repeats) Condensation PF00668.20 EWM24944.1 - 0.00084 18.1 0.0 0.0035 16.1 0.0 1.8 2 0 0 2 2 2 1 Condensation domain Thiolase_N PF00108.23 EWM24944.1 - 0.0049 16.3 0.3 0.012 15.0 0.3 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Epimerase PF01370.21 EWM24944.1 - 0.011 15.2 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family AMP-binding_C_2 PF14535.6 EWM24944.1 - 0.019 15.2 0.0 0.06 13.7 0.0 1.9 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain DUF2842 PF11003.8 EWM24944.1 - 0.82 10.0 12.7 1.6 9.0 1.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2842) Diphthami_syn_2 PF01902.17 EWM24946.1 - 8.5e-38 130.0 0.0 1.6e-37 129.2 0.0 1.4 1 0 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 EWM24946.1 - 7.4e-23 80.9 0.0 2e-09 37.5 0.0 4.0 4 0 0 4 4 4 3 Endoribonuclease L-PSP UCH PF00443.29 EWM24947.1 - 3.3e-42 144.7 0.0 4.7e-41 141.0 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 EWM24947.1 - 4.6e-21 74.3 0.0 9.5e-21 73.3 0.0 1.6 1 0 0 1 1 1 1 Variant UBP zinc finger UCH_1 PF13423.6 EWM24947.1 - 3.4e-12 46.6 0.0 1.8e-06 27.8 0.0 2.7 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 EWM24947.1 - 1.4e-11 44.0 5.9 1.1e-07 31.6 0.7 2.6 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP PF02148.19 EWM24947.1 - 3.9e-09 36.7 0.0 1.4e-08 34.9 0.0 1.9 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UBA_4 PF14555.6 EWM24947.1 - 0.029 14.2 1.5 0.056 13.3 0.2 2.2 2 0 0 2 2 2 0 UBA-like domain Myb_DNA-binding PF00249.31 EWM24948.1 - 5e-25 87.4 3.8 1.3e-11 44.5 1.3 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EWM24948.1 - 8.9e-19 67.5 1.2 8.9e-14 51.5 0.6 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 EWM24948.1 - 0.013 15.5 0.0 9.2 6.4 0.0 2.7 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 EWM24948.1 - 0.062 13.3 0.0 0.71 9.9 0.0 2.3 1 1 1 2 2 2 0 SLIDE DARPP-32 PF05395.12 EWM24948.1 - 1.3 9.2 6.6 0.34 11.1 2.6 2.0 2 0 0 2 2 2 0 Protein phosphatase inhibitor 1/DARPP-32 Glycos_transf_3 PF00591.21 EWM24949.1 - 2.4e-86 289.5 1.5 2.9e-86 289.2 1.5 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 EWM24949.1 - 1.2e-12 47.5 0.2 6.6e-12 45.1 0.0 2.3 3 0 0 3 3 3 1 Glycosyl transferase family, helical bundle domain Pentapeptide PF00805.22 EWM24950.1 - 1.6e-20 72.4 11.9 8.9e-10 38.0 0.2 3.4 1 1 3 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 EWM24950.1 - 4.4e-10 39.6 5.3 3.5e-08 33.5 0.5 3.1 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.6 EWM24950.1 - 4.8e-10 39.5 0.4 2.5e-07 30.8 0.0 2.1 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) PPR PF01535.20 EWM24951.1 - 4.3e-08 32.9 6.4 0.34 11.3 0.1 7.5 8 0 0 8 8 8 2 PPR repeat PPR_2 PF13041.6 EWM24951.1 - 0.00024 21.2 0.3 9.8 6.5 0.0 5.4 5 1 1 6 6 6 1 PPR repeat family Smr PF01713.21 EWM24951.1 - 0.048 14.0 0.2 0.55 10.6 0.1 2.5 2 0 0 2 2 2 0 Smr domain PPR_long PF17177.4 EWM24951.1 - 0.06 12.7 0.5 1.3 8.3 0.1 2.4 2 1 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 EWM24951.1 - 0.078 13.5 1.0 0.71 10.4 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EWM24951.1 - 0.098 13.5 7.7 6 8.0 0.1 5.0 4 1 0 4 4 4 0 Tetratricopeptide repeat PPR_3 PF13812.6 EWM24951.1 - 0.19 11.8 0.1 68 3.6 0.0 3.6 4 0 0 4 4 4 0 Pentatricopeptide repeat domain TRAM_LAG1_CLN8 PF03798.16 EWM24954.1 - 1.6e-15 57.4 15.6 2.3e-15 56.8 15.6 1.3 1 0 0 1 1 1 1 TLC domain zf-C3HC4_3 PF13920.6 EWM24955.1 - 1.6e-06 27.8 12.1 3.2e-06 26.9 12.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EWM24955.1 - 3.5e-06 26.7 12.9 7.8e-06 25.6 12.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EWM24955.1 - 4.5e-06 26.4 14.0 9.4e-06 25.4 14.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EWM24955.1 - 3.7e-05 23.6 12.9 7.3e-05 22.6 12.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EWM24955.1 - 0.0003 20.6 12.0 0.00071 19.4 12.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EWM24955.1 - 0.0014 18.6 10.4 0.0029 17.6 10.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EWM24955.1 - 0.0023 18.2 12.6 0.0049 17.2 12.6 1.6 1 0 0 1 1 1 1 Ring finger domain DUF2935 PF11155.8 EWM24955.1 - 0.015 15.6 0.5 2 8.8 0.1 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF2935) zf-RING_6 PF14835.6 EWM24955.1 - 0.082 12.8 5.0 0.19 11.6 5.0 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein HALZ PF02183.18 EWM24955.1 - 0.36 11.1 25.2 6.5 7.1 1.5 6.9 6 1 0 6 6 6 0 Homeobox associated leucine zipper zf-rbx1 PF12678.7 EWM24955.1 - 0.55 10.6 9.5 1.3 9.4 9.5 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain UFC1 PF08694.11 EWM24956.1 - 4.7e-70 234.2 0.0 5.6e-70 233.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.26 EWM24956.1 - 0.00054 19.6 0.1 0.00086 19.0 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF1415 PF07209.12 EWM24957.1 - 6.3e-40 136.7 0.0 1.4e-39 135.5 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1415) Mito_carr PF00153.27 EWM24958.1 - 1.9e-17 63.0 8.9 2.5e-06 27.3 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein TPR_16 PF13432.6 EWM24959.1 - 5.2e-06 27.0 1.2 3.8e-05 24.2 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF4470 PF14737.6 EWM24959.1 - 0.00022 21.3 0.0 0.00076 19.6 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) TPR_11 PF13414.6 EWM24959.1 - 0.0008 19.0 0.0 0.0021 17.7 0.0 1.8 1 1 0 1 1 1 1 TPR repeat TPR_2 PF07719.17 EWM24959.1 - 0.0017 18.3 2.5 0.011 15.8 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EWM24959.1 - 0.0018 18.0 0.0 0.0072 16.1 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EWM24959.1 - 0.0048 17.0 0.3 0.53 10.6 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EWM24959.1 - 0.019 15.8 0.9 1.5 9.8 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_hydro_108 PF05838.12 EWM24959.1 - 0.083 13.4 0.4 0.21 12.1 0.4 1.7 1 0 0 1 1 1 0 Glycosyl hydrolase 108 adh_short PF00106.25 EWM24961.1 - 1.6e-39 135.4 0.2 2.3e-28 99.0 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EWM24961.1 - 1.5e-24 86.9 0.7 1.3e-19 70.8 0.0 2.1 1 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM24961.1 - 1.5e-05 25.0 0.4 2.5e-05 24.2 0.4 1.3 1 0 0 1 1 1 1 KR domain DFP PF04127.15 EWM24961.1 - 0.052 13.4 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein DUF1776 PF08643.10 EWM24961.1 - 0.053 12.9 0.0 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Cas1_AcylT PF07779.12 EWM24962.1 - 4.5e-92 309.4 14.6 6.3e-92 308.9 14.6 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.6 EWM24962.1 - 0.006 16.4 0.0 0.013 15.3 0.0 1.5 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Lipase_GDSL_2 PF13472.6 EWM24962.1 - 0.0082 16.6 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family SNF2_N PF00176.23 EWM24963.1 - 5.8e-21 74.6 0.0 9.9e-21 73.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EWM24963.1 - 5.2e-07 30.0 0.0 1.3e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HNH PF01844.23 EWM24963.1 - 0.075 13.2 0.2 0.075 13.2 0.2 2.3 3 0 0 3 3 3 0 HNH endonuclease Na_Ca_ex PF01699.24 EWM24964.1 - 3.3e-11 43.4 31.2 1.8e-09 37.8 16.8 2.3 2 1 0 2 2 2 2 Sodium/calcium exchanger protein EF-hand_1 PF00036.32 EWM24964.1 - 3.8e-09 35.5 0.9 3.1e-07 29.4 0.7 2.5 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 EWM24964.1 - 1.3e-07 31.9 0.2 2.4e-07 31.1 0.2 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EWM24964.1 - 1.4e-07 30.8 1.3 0.00027 20.6 0.3 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EWM24964.1 - 3.9e-05 23.4 0.0 8.4e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EWM24964.1 - 0.042 13.4 0.4 0.042 13.4 0.4 2.0 2 0 0 2 2 2 0 EF hand DUF1700 PF08006.11 EWM24964.1 - 4.4 6.8 8.2 12 5.4 8.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF5383 PF17355.2 EWM24964.1 - 6.7 7.1 6.0 43 4.5 1.3 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5383) RVT_3 PF13456.6 EWM24965.1 - 1.2e-27 96.2 0.1 6.7e-25 87.3 0.0 2.6 2 1 0 2 2 2 2 Reverse transcriptase-like RNase_H PF00075.24 EWM24965.1 - 1.4e-06 28.6 0.0 3e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 RNase H Myb_DNA-binding PF00249.31 EWM24966.1 - 2.1e-25 88.6 4.3 1.3e-12 47.7 2.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EWM24966.1 - 1.3e-10 41.4 4.5 0.00018 21.7 1.7 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EWM24966.1 - 5.4e-10 39.0 1.4 0.00023 21.0 0.0 2.5 2 0 0 2 2 2 2 Myb DNA-binding like TRAPP PF04051.16 EWM24968.1 - 1.3e-33 115.8 0.0 1.7e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Proteasome PF00227.26 EWM24969.1 - 4.2e-34 117.7 0.1 5.6e-34 117.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit AAA_lid_3 PF17862.1 EWM24969.1 - 0.0018 18.0 0.1 0.0032 17.2 0.1 1.4 1 0 0 1 1 1 1 AAA+ lid domain ATP_bind_3 PF01171.20 EWM24970.1 - 3.3e-43 147.6 0.0 3.2e-21 75.9 0.0 2.2 2 0 0 2 2 2 2 PP-loop family TilS_C PF11734.8 EWM24970.1 - 9.3e-07 28.2 2.5 2.1e-06 27.1 0.6 2.3 2 0 0 2 2 2 1 TilS substrate C-terminal domain PAPS_reduct PF01507.19 EWM24970.1 - 4.9e-05 23.5 0.0 8.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family CDtoxinA PF03498.14 EWM24970.1 - 0.23 11.1 0.0 0.43 10.2 0.0 1.4 1 0 0 1 1 1 0 Cytolethal distending toxin A/C domain Xpo1 PF08389.12 EWM24971.1 - 2.6e-13 50.3 0.0 4.4e-12 46.3 0.0 2.5 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 EWM24971.1 - 1.6e-07 31.1 0.1 4.7e-07 29.6 0.1 1.8 1 0 0 1 1 1 1 Importin-beta N-terminal domain Rif1_N PF12231.8 EWM24971.1 - 0.06 12.3 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Rap1-interacting factor 1 N terminal Sec6 PF06046.13 EWM24972.1 - 5.5e-43 147.2 3.3 7.5e-43 146.8 3.3 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 COG4 PF08318.12 EWM24972.1 - 0.031 13.4 1.2 0.069 12.2 0.2 2.1 2 0 0 2 2 2 0 COG4 transport protein RPW8 PF05659.11 EWM24972.1 - 0.094 12.4 5.0 1.1 9.0 1.0 3.4 2 1 1 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF3179 PF11376.8 EWM24972.1 - 0.21 10.9 0.4 0.48 9.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3179) DUF5304 PF17230.2 EWM24972.1 - 1.2 9.4 7.3 18 5.5 4.4 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5304) RPA_interact_M PF14767.6 EWM24972.1 - 4.5 7.9 7.1 1.3 9.7 0.2 3.2 3 1 0 3 3 3 0 Replication protein A interacting middle Ge1_WD40 PF16529.5 EWM24973.1 - 3.9e-27 95.1 0.0 1.7e-14 53.6 0.0 2.1 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 EWM24973.1 - 5e-07 30.3 0.2 0.0031 18.3 0.1 3.1 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM24973.1 - 0.0053 17.0 0.0 0.65 10.3 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain PRIMA1 PF16101.5 EWM24973.1 - 5.4 7.1 5.4 13 5.9 5.4 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Nop PF01798.18 EWM24974.1 - 3.6e-85 285.1 0.2 7.3e-85 284.1 0.2 1.5 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EWM24974.1 - 8e-22 77.4 0.4 2.7e-21 75.7 0.4 2.0 1 0 0 1 1 1 1 NOP5NT (NUC127) domain eIF3_subunit PF08597.10 EWM24975.1 - 0.0085 16.0 1.7 0.012 15.5 1.7 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit LAT PF15234.6 EWM24975.1 - 0.047 13.4 3.3 0.072 12.8 3.3 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells Nop14 PF04147.12 EWM24975.1 - 0.23 9.6 5.0 0.28 9.3 5.0 1.1 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.14 EWM24975.1 - 0.75 9.6 3.5 1.3 8.8 3.5 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DNA_pol_phi PF04931.13 EWM24975.1 - 0.78 7.8 5.9 1 7.4 5.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 EWM24975.1 - 0.82 10.1 8.4 2 8.8 8.4 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 EWM24975.1 - 0.9 8.8 7.2 1.2 8.3 7.2 1.1 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 EWM24975.1 - 1.1 8.9 6.0 2.1 8.0 6.0 1.4 1 0 0 1 1 1 0 FAM176 family DUF4746 PF15928.5 EWM24975.1 - 3.8 6.8 6.6 5.3 6.4 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Met_synt_B12 PF02965.17 EWM24976.1 - 1.4e-115 385.5 0.0 2.3e-115 384.8 0.0 1.4 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 EWM24976.1 - 1.7e-74 251.1 0.0 2.9e-74 250.3 0.0 1.4 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 EWM24976.1 - 2.2e-55 188.0 0.4 6.1e-55 186.5 0.3 1.9 2 0 0 2 2 2 1 Pterin binding enzyme B12-binding_2 PF02607.17 EWM24976.1 - 2.4e-24 85.6 0.0 2.4e-24 85.6 0.0 3.0 3 0 0 3 3 3 1 B12 binding domain B12-binding PF02310.19 EWM24976.1 - 5e-17 62.1 1.1 3e-16 59.5 0.3 2.7 3 1 0 3 3 3 1 B12 binding domain LPD7 PF18821.1 EWM24976.1 - 0.11 12.6 0.0 0.85 9.8 0.0 2.6 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 7 Cpn60_TCP1 PF00118.24 EWM24977.1 - 2.4e-88 296.9 13.6 3.7e-88 296.3 13.6 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family IF4E PF01652.18 EWM24978.1 - 1.5e-43 148.3 0.1 2e-43 148.0 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E IF4E PF01652.18 EWM24979.1 - 3.2e-40 137.5 0.0 4.1e-40 137.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E NMD3 PF04981.13 EWM24981.1 - 8e-71 238.3 4.2 1.1e-70 237.8 4.2 1.2 1 0 0 1 1 1 1 NMD3 family zf-RING_4 PF14570.6 EWM24981.1 - 7.2 6.5 8.0 19 5.2 0.0 2.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Aldo_ket_red PF00248.21 EWM24982.1 - 3.8e-48 164.2 0.0 1.4e-46 159.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Ribosomal_S18 PF01084.20 EWM24983.1 - 3e-17 62.6 0.3 7e-17 61.4 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S18 IATP PF04568.12 EWM24983.1 - 0.58 10.6 2.8 0.52 10.8 0.6 2.0 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Ribosomal_S18 PF01084.20 EWM24984.1 - 2.7e-17 62.7 0.0 4.4e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S18 O-FucT PF10250.9 EWM24985.1 - 0.003 17.3 0.0 4.1 7.0 0.0 2.9 3 0 0 3 3 3 2 GDP-fucose protein O-fucosyltransferase Cupin_2 PF07883.11 EWM24986.1 - 1.5e-09 37.4 2.1 0.00016 21.3 0.0 3.0 2 1 0 2 2 2 2 Cupin domain Cupin_1 PF00190.22 EWM24986.1 - 0.0011 18.6 0.0 1.6 8.3 0.0 2.4 2 0 0 2 2 2 2 Cupin Cupin_3 PF05899.12 EWM24986.1 - 0.06 13.1 0.0 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Flavoprotein PF02441.19 EWM24986.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Flavoprotein Cpn10 PF00166.21 EWM24988.1 - 7.8e-47 157.3 0.3 1.2e-22 79.7 0.3 2.1 2 0 0 2 2 2 2 Chaperonin 10 Kd subunit TPR_1 PF00515.28 EWM24989.1 - 4.5e-13 48.4 8.7 0.00011 21.9 0.0 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 EWM24989.1 - 9.9e-13 48.2 12.3 3e-07 30.6 0.1 4.7 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 EWM24989.1 - 2.4e-10 39.7 16.0 0.0042 17.1 0.0 6.0 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 EWM24989.1 - 3.7e-07 30.4 13.2 0.19 12.6 0.0 7.4 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 EWM24989.1 - 1e-06 29.3 11.8 0.0021 18.7 0.0 5.6 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 EWM24989.1 - 1.2e-06 28.2 5.7 0.013 15.5 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EWM24989.1 - 1.4e-05 24.9 9.4 0.19 12.0 0.2 6.0 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 EWM24989.1 - 2.6e-05 24.6 6.7 0.1 13.2 0.1 5.8 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_4 PF07721.14 EWM24989.1 - 3.4e-05 24.1 0.5 1.3 9.9 0.0 4.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EWM24989.1 - 5.6e-05 23.6 4.1 0.17 12.4 0.0 4.6 3 2 1 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EWM24989.1 - 0.00026 21.2 4.2 0.19 12.0 0.1 3.9 4 1 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 EWM24989.1 - 0.00027 20.4 1.5 0.16 11.3 0.9 2.5 2 0 0 2 2 2 2 MalT-like TPR region TPR_10 PF13374.6 EWM24989.1 - 0.00045 20.0 15.4 0.0024 17.7 0.1 5.5 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_21 PF09976.9 EWM24989.1 - 0.0034 17.1 4.8 0.25 11.0 0.1 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat-like domain TPR_11 PF13414.6 EWM24989.1 - 0.04 13.6 7.8 0.048 13.3 0.1 3.7 3 1 1 4 4 4 0 TPR repeat TPR_17 PF13431.6 EWM24989.1 - 0.049 14.0 3.7 11 6.6 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.9 EWM24989.1 - 0.089 12.5 0.4 0.36 10.5 0.1 2.1 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TPR_9 PF13371.6 EWM24989.1 - 0.13 12.4 0.9 27 5.0 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat NARP1 PF12569.8 EWM24989.1 - 0.33 9.8 2.0 12 4.7 0.0 3.0 2 1 0 2 2 2 0 NMDA receptor-regulated protein 1 SRP_TPR_like PF17004.5 EWM24989.1 - 0.35 10.9 1.2 8.4 6.5 0.0 2.8 2 1 1 3 3 3 0 Putative TPR-like repeat PPR PF01535.20 EWM24989.1 - 0.47 10.8 11.3 21 5.6 0.0 5.8 6 0 0 6 6 5 0 PPR repeat TPR_1 PF00515.28 EWM24990.1 - 4.5e-13 48.4 8.7 0.00011 21.9 0.0 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 EWM24990.1 - 9.9e-13 48.2 12.3 3e-07 30.6 0.1 4.7 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 EWM24990.1 - 2.4e-10 39.7 16.0 0.0042 17.1 0.0 6.0 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 EWM24990.1 - 3.7e-07 30.4 13.2 0.19 12.6 0.0 7.4 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 EWM24990.1 - 1e-06 29.3 11.8 0.0021 18.7 0.0 5.6 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 EWM24990.1 - 1.2e-06 28.2 5.7 0.013 15.5 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EWM24990.1 - 1.4e-05 24.9 9.4 0.19 12.0 0.2 6.0 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 EWM24990.1 - 2.6e-05 24.6 6.7 0.1 13.2 0.1 5.8 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_4 PF07721.14 EWM24990.1 - 3.4e-05 24.1 0.5 1.3 9.9 0.0 4.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EWM24990.1 - 5.6e-05 23.6 4.1 0.17 12.4 0.0 4.6 3 2 1 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EWM24990.1 - 0.00026 21.2 4.2 0.19 12.0 0.1 3.9 4 1 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 EWM24990.1 - 0.00027 20.4 1.5 0.16 11.3 0.9 2.5 2 0 0 2 2 2 2 MalT-like TPR region TPR_10 PF13374.6 EWM24990.1 - 0.00045 20.0 15.4 0.0024 17.7 0.1 5.5 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_21 PF09976.9 EWM24990.1 - 0.0034 17.1 4.8 0.25 11.0 0.1 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat-like domain TPR_11 PF13414.6 EWM24990.1 - 0.04 13.6 7.8 0.048 13.3 0.1 3.7 3 1 1 4 4 4 0 TPR repeat TPR_17 PF13431.6 EWM24990.1 - 0.049 14.0 3.7 11 6.6 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.9 EWM24990.1 - 0.089 12.5 0.4 0.36 10.5 0.1 2.1 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TPR_9 PF13371.6 EWM24990.1 - 0.13 12.4 0.9 27 5.0 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat NARP1 PF12569.8 EWM24990.1 - 0.33 9.8 2.0 12 4.7 0.0 3.0 2 1 0 2 2 2 0 NMDA receptor-regulated protein 1 SRP_TPR_like PF17004.5 EWM24990.1 - 0.35 10.9 1.2 8.4 6.5 0.0 2.8 2 1 1 3 3 3 0 Putative TPR-like repeat PPR PF01535.20 EWM24990.1 - 0.47 10.8 11.3 21 5.6 0.0 5.8 6 0 0 6 6 5 0 PPR repeat MIF PF01187.18 EWM24991.1 - 9.1e-18 64.6 0.0 1.4e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.21 EWM24991.1 - 1.3e-05 25.1 0.0 0.041 13.8 0.0 2.3 2 0 0 2 2 2 2 Tautomerase enzyme zf-HIT PF04438.16 EWM24992.1 - 8.5e-07 28.7 14.7 1.9e-06 27.6 14.7 1.6 1 0 0 1 1 1 1 HIT zinc finger DUF1392 PF07154.11 EWM24992.1 - 0.17 12.0 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1392) zf-MYND PF01753.18 EWM24992.1 - 5.2 7.2 12.8 10 6.3 12.8 1.5 1 0 0 1 1 1 0 MYND finger Pkinase PF00069.25 EWM24993.1 - 1.4e-70 237.7 0.0 1.6e-70 237.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM24993.1 - 5.3e-40 137.3 0.0 6.5e-40 137.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EWM24993.1 - 9.9e-06 25.1 0.0 3.9e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EWM24993.1 - 0.11 12.5 0.5 0.55 10.1 0.1 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EWM24993.1 - 0.26 10.3 0.0 0.38 9.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Adaptin_N PF01602.20 EWM24997.1 - 8.3e-111 371.1 0.0 1e-110 370.8 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 EWM24997.1 - 1e-15 57.9 0.0 1.8e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 EWM24997.1 - 8.7e-14 51.8 0.0 1.6e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 EWM24997.1 - 1.2e-11 44.9 0.5 2.3e-09 37.5 0.0 2.4 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EWM24997.1 - 0.00054 20.0 1.1 3.5 8.2 0.1 3.9 3 0 0 3 3 3 1 HEAT repeat Choline_transpo PF04515.12 EWM24998.1 - 1.6e-65 221.5 26.3 1.6e-65 221.5 26.3 2.6 2 1 1 3 3 3 2 Plasma-membrane choline transporter HR_lesion PF05514.11 EWM24998.1 - 0.004 17.4 0.8 0.004 17.4 0.8 2.4 2 1 0 2 2 2 1 HR-like lesion-inducing DUF4516 PF14990.6 EWM24998.1 - 6.9 6.5 5.8 6.1 6.6 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4516) Glyco_hydro_79n PF03662.14 EWM24999.1 - 5.5e-96 321.2 0.0 6.9e-96 320.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 79, N-terminal domain Glyco_hydro_cc PF11790.8 EWM24999.1 - 0.052 13.1 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core W2 PF02020.18 EWM25000.1 - 4.7e-16 58.7 0.1 4.7e-16 58.7 0.1 2.0 2 1 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon DUF4410 PF14366.6 EWM25000.1 - 0.086 12.8 10.6 0.27 11.1 10.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4410) DUF4545 PF15078.6 EWM25000.1 - 0.89 8.5 3.0 1.2 8.0 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4545) FXMRP1_C_core PF12235.8 EWM25000.1 - 1.3 9.7 7.5 3.7 8.2 7.5 1.8 1 1 0 1 1 1 0 Fragile X-related 1 protein core C terminal Gar1 PF04410.14 EWM25001.1 - 2e-24 86.1 0.1 2.4e-24 85.9 0.1 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region PhoD PF09423.10 EWM25003.1 - 2.3e-16 59.8 0.0 1.6e-15 57.0 0.0 2.0 1 1 0 1 1 1 1 PhoD-like phosphatase Ribul_P_3_epim PF00834.19 EWM25004.1 - 2e-66 223.2 0.0 2.4e-66 222.9 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family PG_binding_3 PF09374.10 EWM25004.1 - 0.052 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Predicted Peptidoglycan domain OMPdecase PF00215.24 EWM25004.1 - 0.13 11.9 0.1 1.4 8.5 0.0 2.1 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Fib_alpha PF08702.10 EWM25005.1 - 0.0029 17.8 1.2 0.0029 17.8 1.2 5.4 3 1 4 7 7 7 2 Fibrinogen alpha/beta chain family ABC1 PF03109.16 EWM25006.1 - 2.1e-21 76.3 0.0 3.7e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EWM25006.1 - 0.0028 17.6 0.6 0.0052 16.7 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Ribosomal_S15 PF00312.22 EWM25006.1 - 0.027 14.7 0.0 0.058 13.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S15 Pkinase_Tyr PF07714.17 EWM25006.1 - 0.042 13.1 0.0 1 8.6 0.0 2.2 2 0 0 2 2 2 0 Protein tyrosine kinase RIO1 PF01163.22 EWM25006.1 - 0.06 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 RIO1 family zf-C2H2 PF00096.26 EWM25008.1 - 1.4e-19 69.3 20.5 4.8e-06 26.7 0.9 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EWM25008.1 - 7.6e-11 41.9 18.2 0.005 17.6 0.4 5.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EWM25008.1 - 6.4e-06 26.4 9.0 0.0018 18.6 0.4 3.5 3 0 0 3 3 3 1 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 EWM25008.1 - 1.2e-05 25.5 0.3 1.2e-05 25.5 0.3 4.8 4 1 0 4 4 3 2 Zinc-finger double domain Pes-10 PF07149.11 EWM25008.1 - 0.00012 21.2 2.7 0.00017 20.7 2.7 1.1 1 0 0 1 1 1 1 Pes-10 Nop14 PF04147.12 EWM25008.1 - 0.0023 16.2 10.4 0.0032 15.8 10.4 1.1 1 0 0 1 1 1 1 Nop14-like family NOA36 PF06524.12 EWM25008.1 - 0.0076 15.6 4.2 0.0076 15.6 4.2 2.1 2 0 0 2 2 2 1 NOA36 protein BSP_II PF05432.11 EWM25008.1 - 0.015 15.1 8.9 0.021 14.5 8.9 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Raftlin PF15250.6 EWM25008.1 - 0.017 13.9 6.3 0.025 13.4 6.3 1.1 1 0 0 1 1 1 0 Raftlin CHORD PF04968.12 EWM25008.1 - 0.04 14.6 12.9 1.1 10.0 0.3 4.5 3 1 1 4 4 4 0 CHORD FOXP-CC PF16159.5 EWM25008.1 - 0.043 14.5 0.6 0.043 14.5 0.6 5.9 5 1 1 6 6 4 0 FOXP coiled-coil domain SDA1 PF05285.12 EWM25008.1 - 0.097 12.1 12.6 0.13 11.7 12.6 1.1 1 0 0 1 1 1 0 SDA1 Myc_N PF01056.18 EWM25008.1 - 0.13 12.1 4.4 0.18 11.7 3.9 1.5 2 0 0 2 2 1 0 Myc amino-terminal region Pox_Ag35 PF03286.14 EWM25008.1 - 0.14 11.9 7.3 0.28 11.0 7.3 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein zf-H2C2_5 PF13909.6 EWM25008.1 - 0.16 11.7 0.2 0.16 11.7 0.2 4.1 4 0 0 4 4 3 0 C2H2-type zinc-finger domain CDC45 PF02724.14 EWM25008.1 - 0.18 10.1 15.0 0.25 9.6 15.0 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-C2H2_aberr PF17017.5 EWM25008.1 - 0.2 11.8 11.6 3.7 7.7 0.5 3.5 2 1 2 4 4 4 0 Aberrant zinc-finger DUF4746 PF15928.5 EWM25008.1 - 0.28 10.6 8.0 0.45 9.9 8.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Mpp10 PF04006.12 EWM25008.1 - 0.34 9.3 14.2 0.46 8.9 14.2 1.1 1 0 0 1 1 1 0 Mpp10 protein DUF913 PF06025.12 EWM25008.1 - 0.92 8.4 3.7 1.4 7.8 3.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RXT2_N PF08595.11 EWM25008.1 - 1.1 9.3 7.1 1.9 8.5 7.1 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal zf-TRAF PF02176.18 EWM25008.1 - 1.1 10.0 11.0 0.25 12.0 0.9 3.5 3 0 0 3 3 3 0 TRAF-type zinc finger zf-C2H2_2 PF12756.7 EWM25008.1 - 1.3 9.4 12.2 0.31 11.4 4.1 3.6 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) Sporozoite_P67 PF05642.11 EWM25008.1 - 1.3 7.0 12.3 0.02 13.0 4.6 1.7 2 0 0 2 2 2 0 Sporozoite P67 surface antigen MscS_TM PF12794.7 EWM25008.1 - 1.4 7.8 5.1 2.3 7.0 5.1 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Paf1 PF03985.13 EWM25008.1 - 1.6 7.7 16.1 2.2 7.2 16.1 1.1 1 0 0 1 1 1 0 Paf1 Vfa1 PF08432.10 EWM25008.1 - 1.7 8.9 10.4 2.8 8.2 10.4 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PGA2 PF07543.12 EWM25008.1 - 1.9 8.5 8.8 3.4 7.7 8.8 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 FYDLN_acid PF09538.10 EWM25008.1 - 2.2 9.0 15.4 1.4 9.7 12.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF4820 PF16091.5 EWM25008.1 - 2.9 7.2 6.0 4.7 6.5 6.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) FAM176 PF14851.6 EWM25008.1 - 3.2 7.4 9.7 7.4 6.2 9.7 1.6 1 0 0 1 1 1 0 FAM176 family SAP PF02037.27 EWM25009.1 - 1.2e-13 50.5 4.4 2.2e-13 49.6 4.4 1.5 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 EWM25009.1 - 1.3e-07 31.3 16.1 0.00083 19.1 1.2 3.5 2 1 1 3 3 3 2 Tho1/MOS11 C-terminal domain HeH PF12949.7 EWM25009.1 - 0.00028 20.5 0.6 0.00084 19.0 0.6 1.9 1 0 0 1 1 1 1 HeH/LEM domain DUF4245 PF14030.6 EWM25009.1 - 0.031 14.3 0.1 0.031 14.3 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4245) Telomere_Sde2_2 PF13297.6 EWM25009.1 - 0.037 13.7 0.8 0.12 12.1 0.8 1.9 1 0 0 1 1 1 0 Telomere stability C-terminal Ish1 PF10281.9 EWM25009.1 - 0.18 12.2 0.4 3 8.2 0.6 2.8 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein TFIIA PF03153.13 EWM25009.1 - 0.19 11.7 2.5 0.25 11.3 2.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DnaJ PF00226.31 EWM25010.1 - 1.5e-22 79.4 5.5 3e-22 78.5 3.5 2.6 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.17 EWM25010.1 - 1.7e-19 68.3 25.9 6.1e-06 26.0 0.1 9.7 11 1 1 12 12 11 5 Tetratricopeptide repeat TPR_1 PF00515.28 EWM25010.1 - 1.6e-18 65.6 9.2 7.8e-06 25.5 0.0 7.7 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 EWM25010.1 - 1.3e-14 54.4 16.3 0.00014 22.3 0.9 5.8 3 3 3 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 EWM25010.1 - 1.8e-14 53.1 5.2 0.00037 20.1 0.1 6.4 6 0 0 6 6 6 3 TPR repeat TPR_8 PF13181.6 EWM25010.1 - 1.5e-13 49.8 1.3 0.0026 17.8 0.0 6.8 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EWM25010.1 - 1.5e-11 44.1 22.8 0.12 13.2 0.0 8.5 4 3 5 9 9 9 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EWM25010.1 - 1.6e-10 41.0 4.7 0.01 16.0 0.0 4.3 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 EWM25010.1 - 1.5e-09 37.8 1.2 0.68 10.1 0.0 5.2 4 1 1 5 5 5 3 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.6 EWM25010.1 - 1.4e-08 35.2 24.0 0.013 16.1 0.9 6.2 3 2 2 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 EWM25010.1 - 6.4e-07 29.0 5.9 2.4 8.4 0.3 6.8 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 EWM25010.1 - 1.7e-06 28.0 1.4 0.65 10.5 0.0 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 EWM25010.1 - 2.5e-06 27.7 18.5 0.32 11.3 0.3 6.8 6 2 1 7 7 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 EWM25010.1 - 8.2e-06 25.9 13.9 2.2 8.5 0.1 5.8 3 3 3 6 6 6 3 Tetratricopeptide repeat TPR_4 PF07721.14 EWM25010.1 - 9.2e-05 22.7 8.2 1.1 10.1 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 EWM25010.1 - 0.06 13.2 8.4 34 4.5 0.2 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EWM25010.1 - 0.078 13.7 19.2 19 6.2 0.0 8.2 9 0 0 9 9 8 0 Tetratricopeptide repeat BTAD PF03704.17 EWM25010.1 - 0.087 13.3 17.3 0.23 11.9 0.8 4.9 3 3 1 4 4 4 0 Bacterial transcriptional activator domain YrbL-PhoP_reg PF10707.9 EWM25010.1 - 0.12 11.9 1.1 0.75 9.3 0.1 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL TPR_20 PF14561.6 EWM25010.1 - 0.27 11.6 13.2 1.4 9.3 0.5 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 EWM25010.1 - 0.28 10.7 2.1 7.6 6.1 0.1 3.1 3 0 0 3 3 3 0 SHNi-TPR HrpB1_HrpK PF09613.10 EWM25010.1 - 0.56 9.9 4.5 0.28 10.8 0.8 2.3 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) Phage_holin_6_1 PF09682.10 EWM25010.1 - 4.5 7.8 8.2 3 8.3 4.5 2.4 2 0 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) mTERF PF02536.14 EWM25011.1 - 5.2e-42 143.9 0.0 4.8e-18 65.1 0.0 3.0 1 1 2 3 3 3 3 mTERF HTH_31 PF13560.6 EWM25011.1 - 0.016 15.5 3.0 7.6 7.0 0.1 4.4 4 0 0 4 4 4 0 Helix-turn-helix domain Gp37 PF09646.10 EWM25011.1 - 0.055 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Gp37 protein DisA-linker PF10635.9 EWM25013.1 - 0.023 14.5 0.0 0.026 14.3 0.0 1.1 1 0 0 1 1 1 0 DisA bacterial checkpoint controller linker region Popeye PF04831.13 EWM25013.1 - 0.16 12.1 0.1 0.19 11.9 0.1 1.1 1 0 0 1 1 1 0 Popeye protein conserved region zf-C2H2_4 PF13894.6 EWM25014.1 - 0.023 15.5 6.0 1.3 10.1 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-BED PF02892.15 EWM25014.1 - 0.06 13.4 1.5 0.63 10.1 0.1 2.4 2 0 0 2 2 2 0 BED zinc finger Dus PF01207.17 EWM25015.1 - 1.3e-67 228.1 0.0 1.7e-67 227.7 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 EWM25015.1 - 0.00017 21.2 0.0 0.00057 19.4 0.0 1.4 1 1 0 1 1 1 1 Histidine biosynthesis protein TMP-TENI PF02581.17 EWM25015.1 - 0.057 12.7 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase NMO PF03060.15 EWM25015.1 - 0.063 12.6 0.0 0.3 10.4 0.0 1.9 2 0 0 2 2 2 0 Nitronate monooxygenase WD40 PF00400.32 EWM25016.1 - 2.6e-41 138.8 30.5 4.5e-08 33.6 1.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM25016.1 - 1.1e-12 48.0 1.7 0.21 11.9 0.0 6.1 3 1 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 EWM25016.1 - 0.014 14.7 0.1 4.6 6.5 0.0 2.8 2 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal SH3_9 PF14604.6 EWM25016.1 - 0.015 15.1 1.0 0.027 14.3 0.2 1.8 2 0 0 2 2 2 0 Variant SH3 domain Arm PF00514.23 EWM25018.1 - 1.4e-48 161.5 30.7 3.6e-11 42.7 0.0 9.3 9 2 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EWM25018.1 - 2.2e-18 66.4 1.3 1.4e-06 28.6 0.0 5.1 1 1 2 5 5 5 4 HEAT repeats HEAT_EZ PF13513.6 EWM25018.1 - 1.4e-17 63.7 1.0 2.1e-05 24.9 0.0 4.9 4 0 0 4 4 4 3 HEAT-like repeat HEAT PF02985.22 EWM25018.1 - 5.6e-10 38.6 6.6 0.082 13.2 0.0 7.6 8 0 0 8 8 8 2 HEAT repeat Arm_3 PF16186.5 EWM25018.1 - 0.00038 19.9 0.3 0.5 10.0 0.0 3.1 3 0 0 3 3 3 2 Atypical Arm repeat RICTOR_V PF14668.6 EWM25018.1 - 0.00072 19.8 0.2 0.71 10.1 0.0 3.7 4 1 1 5 5 4 1 Rapamycin-insensitive companion of mTOR, domain 5 DUF3361 PF11841.8 EWM25018.1 - 0.012 15.5 0.1 1.6 8.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.8 EWM25018.1 - 0.024 14.7 0.0 1.3 9.1 0.0 3.1 3 0 0 3 3 3 0 V-ATPase subunit H Arm_2 PF04826.13 EWM25018.1 - 0.025 14.0 0.0 6.1 6.2 0.0 2.3 2 0 0 2 2 2 0 Armadillo-like FYVE_2 PF02318.16 EWM25018.1 - 0.056 13.6 5.7 0.13 12.5 5.7 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger Atx10homo_assoc PF09759.9 EWM25018.1 - 0.081 13.0 0.3 23 5.1 0.0 3.0 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain zf-piccolo PF05715.13 EWM25018.1 - 0.65 10.2 10.4 1.5 9.0 10.4 1.6 1 0 0 1 1 1 0 Piccolo Zn-finger Nucleotid_trans PF03407.16 EWM25019.1 - 9.1e-28 97.7 0.0 6.3e-24 85.1 0.0 2.4 1 1 1 2 2 2 2 Nucleotide-diphospho-sugar transferase Cupin_8 PF13621.6 EWM25021.1 - 1.8e-13 50.8 0.0 2.7e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 EWM25021.1 - 1.8e-08 34.8 0.0 1.5e-07 31.8 0.0 2.2 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 EWM25021.1 - 0.0041 16.6 0.0 0.01 15.3 0.0 1.7 2 0 0 2 2 2 1 Cupin superfamily protein AAA_11 PF13086.6 EWM25022.1 - 1.4e-10 41.4 0.0 2.5e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EWM25022.1 - 3.1e-07 30.3 0.0 5e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EWM25022.1 - 8.6e-06 26.2 0.0 1.7e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EWM25022.1 - 1.4e-05 25.2 0.0 2.2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PIF1 PF05970.14 EWM25022.1 - 0.00013 21.3 0.0 0.00018 20.8 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_16 PF13191.6 EWM25022.1 - 0.0041 17.5 0.0 0.0081 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EWM25022.1 - 0.005 17.3 0.0 0.0086 16.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 EWM25022.1 - 0.039 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_25 PF13481.6 EWM25022.1 - 0.049 13.2 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EWM25022.1 - 0.14 12.4 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 EWM25022.1 - 0.15 11.6 0.0 0.21 11.1 0.0 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 EWM25022.1 - 0.22 10.7 0.0 1 8.5 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) GST_N_4 PF17172.4 EWM25023.1 - 4.1e-11 43.5 0.0 7.4e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 EWM25023.1 - 4.6e-11 43.1 0.0 7.6e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 EWM25023.1 - 1.2e-10 41.0 0.2 2.2e-10 40.1 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EWM25023.1 - 0.00019 21.4 0.1 0.0005 20.0 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain CTP_transf_like PF01467.26 EWM25024.1 - 1e-29 103.6 0.0 1.7e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like Macoilin PF09726.9 EWM25024.1 - 0.38 9.3 5.0 0.45 9.0 5.0 1.1 1 0 0 1 1 1 0 Macoilin family Reovirus_M2 PF05993.12 EWM25025.1 - 0.25 9.4 0.0 0.36 8.9 0.0 1.1 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) FBPase PF00316.20 EWM25027.1 - 2e-36 125.3 0.0 2.7e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain UMP1 PF05348.11 EWM25028.1 - 2.4e-26 92.3 0.0 2.7e-26 92.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 PFOR_II PF17147.4 EWM25028.1 - 0.15 12.4 0.0 0.2 12.0 0.0 1.2 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II UAF_Rrn10 PF05234.11 EWM25030.1 - 0.037 14.3 0.0 0.09 13.0 0.0 1.6 1 0 0 1 1 1 0 UAF complex subunit Rrn10 MaoC_dehydratas PF01575.19 EWM25031.1 - 8.7e-12 44.7 0.5 4.8e-11 42.3 0.1 2.1 2 0 0 2 2 2 1 MaoC like domain Lamprin PF06403.11 EWM25031.1 - 0.0029 17.6 0.7 0.0029 17.6 0.7 1.8 2 0 0 2 2 2 1 Lamprin YdjM PF04307.14 EWM25031.1 - 0.018 14.4 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase Putative_PNPOx PF01243.20 EWM25034.1 - 2.8e-19 69.1 0.0 2e-13 50.3 0.0 2.4 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 EWM25034.1 - 6.1e-18 64.6 1.8 1.4e-17 63.5 1.8 1.7 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region DUF572 PF04502.13 EWM25035.1 - 4.6e-52 177.7 0.0 5.9e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) SnoaL_3 PF13474.6 EWM25036.1 - 8.1e-07 29.3 0.1 1.4e-06 28.5 0.1 1.4 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 EWM25036.1 - 0.00089 19.9 0.0 0.0026 18.4 0.0 1.9 2 0 0 2 2 2 1 SnoaL-like domain NTF2 PF02136.20 EWM25036.1 - 0.0049 17.4 0.0 0.014 15.9 0.0 1.7 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 EWM25036.1 - 0.12 12.8 0.1 0.29 11.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) SnoaL_4 PF13577.6 EWM25036.1 - 0.2 11.8 0.5 0.68 10.1 0.5 1.9 1 1 0 1 1 1 0 SnoaL-like domain CaMKII_AD PF08332.10 EWM25036.1 - 0.2 11.8 2.4 0.72 10.0 2.4 1.9 1 1 0 1 1 1 0 Calcium/calmodulin dependent protein kinase II association domain SnoaL_3 PF13474.6 EWM25037.1 - 4.5e-07 30.2 0.1 7.7e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 EWM25037.1 - 0.00061 20.4 0.0 0.0015 19.1 0.0 1.7 1 1 0 1 1 1 1 SnoaL-like domain NTF2 PF02136.20 EWM25037.1 - 0.0048 17.5 0.0 0.0083 16.7 0.0 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 EWM25037.1 - 0.069 13.5 0.1 0.16 12.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) SnoaL_4 PF13577.6 EWM25037.1 - 0.1 12.7 0.5 0.39 10.9 0.5 1.9 1 1 0 1 1 1 0 SnoaL-like domain CaMKII_AD PF08332.10 EWM25037.1 - 0.11 12.7 2.4 0.4 10.8 2.4 1.8 1 1 0 1 1 1 0 Calcium/calmodulin dependent protein kinase II association domain XPG_I PF00867.18 EWM25038.1 - 1e-20 73.9 0.0 2.3e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EWM25038.1 - 2.1e-20 73.1 0.0 1.8e-19 70.0 0.0 2.2 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I_2 PF12813.7 EWM25038.1 - 2.3e-05 24.0 0.9 4.1e-05 23.2 0.9 1.3 1 0 0 1 1 1 1 XPG domain containing REV PF00424.18 EWM25038.1 - 0.092 12.8 1.2 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) Hydrolase_4 PF12146.8 EWM25039.1 - 6.6e-58 195.8 0.0 1.1e-57 195.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EWM25039.1 - 2.2e-09 37.3 0.9 1.6e-06 27.9 1.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EWM25039.1 - 2e-07 31.9 2.7 2.9e-07 31.3 2.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EWM25039.1 - 1.9e-05 24.9 0.1 3.3e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Thioesterase domain LIDHydrolase PF10230.9 EWM25039.1 - 0.0086 15.7 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_2 PF02230.16 EWM25039.1 - 0.0087 15.9 0.1 0.027 14.3 0.0 1.8 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Esterase PF00756.20 EWM25039.1 - 0.025 14.2 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 Putative esterase PGAP1 PF07819.13 EWM25039.1 - 0.042 13.6 0.0 0.062 13.0 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF900 PF05990.12 EWM25039.1 - 0.062 12.8 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.15 EWM25039.1 - 0.085 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF2905 PF11146.8 EWM25040.1 - 2.1e-09 37.4 0.3 2.8e-09 37.0 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2905) PTPRCAP PF15713.5 EWM25041.1 - 0.0013 19.0 3.9 0.0013 19.0 3.9 2.1 2 0 0 2 2 2 1 Protein tyrosine phosphatase receptor type C-associated Ribosomal_60s PF00428.19 EWM25041.1 - 0.0058 17.2 5.5 0.0058 17.2 5.5 2.1 3 0 0 3 3 3 1 60s Acidic ribosomal protein Pox_Ag35 PF03286.14 EWM25041.1 - 0.092 12.5 6.5 0.046 13.5 1.9 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein PKS_DE PF18369.1 EWM25041.1 - 0.62 10.7 0.1 0.62 10.7 0.1 3.5 4 0 0 4 4 4 0 Polyketide synthase dimerisation element domain DNA_pol_phi PF04931.13 EWM25041.1 - 1.7 6.7 4.2 2.5 6.1 4.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi PBP1_TM PF14812.6 EWM25041.1 - 3.4 8.1 11.0 10 6.6 11.0 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 EWM25041.1 - 4.2 6.6 6.2 6.3 6.0 6.2 1.2 1 0 0 1 1 1 0 NOA36 protein WRNPLPNID PF15017.6 EWM25041.1 - 6.1 7.8 11.6 4.8 8.1 8.4 2.3 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box CDC45 PF02724.14 EWM25041.1 - 7.1 4.8 6.7 11 4.1 6.7 1.3 1 0 0 1 1 1 0 CDC45-like protein DEAD PF00270.29 EWM25042.1 - 1.9e-34 118.9 0.0 3.5e-34 118.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EWM25042.1 - 1.5e-19 70.4 0.0 5.4e-19 68.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.6 EWM25042.1 - 0.00045 20.4 0.0 0.00083 19.6 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 EWM25042.1 - 0.014 15.4 0.0 0.035 14.1 0.0 1.6 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 EWM25042.1 - 0.018 14.4 0.0 2 7.6 0.0 2.1 2 0 0 2 2 2 0 SecA DEAD-like domain AAA_25 PF13481.6 EWM25042.1 - 0.1 12.2 0.1 0.21 11.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain CMS1 PF14617.6 EWM25042.1 - 0.21 10.9 0.0 0.37 10.1 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Cellulose_synt PF03552.14 EWM25045.1 - 1.9e-26 92.8 14.3 3.4e-15 55.6 1.6 3.4 2 1 2 4 4 4 3 Cellulose synthase Glyco_tranf_2_3 PF13641.6 EWM25045.1 - 7.2e-26 91.5 0.0 1.2e-25 90.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EWM25045.1 - 4.1e-19 69.3 0.8 4.1e-19 69.3 0.8 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EWM25045.1 - 2.4e-17 63.2 0.0 4.7e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EWM25045.1 - 2.4e-13 49.9 0.0 6.6e-13 48.5 0.0 1.7 1 1 1 2 2 2 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 EWM25045.1 - 0.00064 18.5 0.2 0.23 10.0 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase DUF373 PF04123.13 EWM25045.1 - 1.3 8.3 6.8 0.066 12.6 1.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Peptidase_C1 PF00112.23 EWM25047.1 - 2.6e-48 165.0 0.4 3.9e-48 164.4 0.4 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EWM25047.1 - 6.8e-06 26.4 0.1 1.2e-05 25.7 0.1 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) TFIIA_gamma_N PF02268.16 EWM25049.1 - 1.3e-07 31.5 0.0 2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain ADH_N PF08240.12 EWM25050.1 - 7e-33 112.8 0.8 1.3e-32 111.9 0.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EWM25050.1 - 2.3e-21 76.2 0.5 2.3e-21 76.2 0.5 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EWM25050.1 - 4.1e-05 24.6 0.1 0.0001 23.4 0.0 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 EWM25050.1 - 0.0081 15.6 0.2 0.016 14.7 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase ADH_N PF08240.12 EWM25051.1 - 7e-33 112.8 0.8 1.3e-32 111.9 0.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EWM25051.1 - 2.3e-21 76.2 0.5 2.3e-21 76.2 0.5 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EWM25051.1 - 4.1e-05 24.6 0.1 0.0001 23.4 0.0 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 EWM25051.1 - 0.0081 15.6 0.2 0.016 14.7 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase ORC_WH_C PF18137.1 EWM25053.1 - 2.1e-33 115.4 0.8 3.9e-32 111.2 0.0 2.5 2 0 0 2 2 2 1 Origin recognition complex winged helix C-terminal ORC3_N PF07034.11 EWM25053.1 - 5.4e-15 55.3 0.1 9.9e-15 54.5 0.1 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus Sulfate_transp PF00916.20 EWM25054.1 - 9.7e-63 212.2 12.8 1.3e-62 211.8 12.8 1.1 1 0 0 1 1 1 1 Sulfate permease family ATPase_2 PF01637.18 EWM25054.1 - 0.22 11.4 0.0 0.34 10.8 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea SdpI PF13630.6 EWM25054.1 - 0.49 10.5 0.1 0.49 10.5 0.1 2.9 3 0 0 3 3 3 0 SdpI/YhfL protein family Glycolytic PF00274.19 EWM25056.1 - 3.6e-127 423.9 0.0 4.1e-127 423.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I SSTK-IP PF15836.5 EWM25056.1 - 0.003 17.7 0.3 0.0077 16.4 0.3 1.6 1 0 0 1 1 1 1 SSTK-interacting protein, TSSK6-activating co-chaperone protein Glycolytic PF00274.19 EWM25057.1 - 3e-127 424.2 0.0 3.5e-127 424.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I SSTK-IP PF15836.5 EWM25057.1 - 0.036 14.2 0.2 0.086 13.0 0.2 1.7 1 0 0 1 1 1 0 SSTK-interacting protein, TSSK6-activating co-chaperone protein Cnd1 PF12717.7 EWM25058.1 - 1.1e-25 90.5 7.6 5.2e-21 75.4 0.0 5.0 6 0 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 EWM25058.1 - 1.5e-06 27.6 0.8 6.2e-06 25.6 0.2 2.3 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Adaptin_N PF01602.20 EWM25058.1 - 0.00017 20.3 1.4 0.00017 20.3 1.4 3.2 4 1 0 5 5 5 1 Adaptin N terminal region HEAT_EZ PF13513.6 EWM25058.1 - 0.045 14.3 20.6 2.8 8.5 0.3 7.5 6 3 1 7 7 7 0 HEAT-like repeat HEAT_2 PF13646.6 EWM25058.1 - 0.086 13.2 0.1 0.086 13.2 0.1 6.9 6 1 2 8 8 8 0 HEAT repeats UNC45-central PF11701.8 EWM25058.1 - 0.09 12.7 1.3 6.7 6.6 0.1 3.9 3 1 0 3 3 3 0 Myosin-binding striated muscle assembly central Lsm_C PF14894.6 EWM25058.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Lsm C-terminal HEAT PF02985.22 EWM25058.1 - 1 9.8 27.5 2.3 8.7 0.3 8.2 9 0 0 9 9 9 0 HEAT repeat Cohesin_HEAT PF12765.7 EWM25058.1 - 7.2 7.0 12.8 3.3 8.1 0.2 4.6 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion DUF202 PF02656.15 EWM25059.1 - 7.2e-17 61.6 1.2 1.3e-16 60.8 0.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) MscS_TM PF12794.7 EWM25059.1 - 0.015 14.2 1.6 0.018 13.9 1.6 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Clc-like PF07062.12 EWM25059.1 - 0.093 12.2 3.2 0.23 10.9 3.2 1.5 1 1 0 1 1 1 0 Clc-like TRP PF06011.12 EWM25059.1 - 0.2 10.3 1.9 0.13 10.9 0.2 1.5 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel Pkinase PF00069.25 EWM25060.1 - 3.1e-57 193.9 0.1 1.2e-56 192.0 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain adh_short PF00106.25 EWM25060.1 - 1.8e-42 145.0 0.8 3.4e-42 144.1 0.8 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EWM25060.1 - 1.8e-28 99.7 0.5 6.9e-28 97.8 0.6 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Pkinase_Tyr PF07714.17 EWM25060.1 - 9.6e-24 84.0 0.0 2.9e-23 82.5 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase KR PF08659.10 EWM25060.1 - 3.3e-07 30.4 0.3 7.5e-07 29.2 0.3 1.5 1 0 0 1 1 1 1 KR domain SOG2 PF10428.9 EWM25060.1 - 2 7.5 22.8 0.44 9.7 12.8 2.4 2 0 0 2 2 2 0 RAM signalling pathway protein Aph-1 PF06105.12 EWM25062.1 - 1.1e-38 133.0 17.2 1.4e-38 132.6 17.2 1.0 1 0 0 1 1 1 1 Aph-1 protein Amastin PF07344.11 EWM25062.1 - 0.016 15.1 3.0 0.016 15.1 3.0 2.4 1 1 1 2 2 2 0 Amastin surface glycoprotein MtN3_slv PF03083.16 EWM25062.1 - 0.26 11.4 4.6 0.098 12.7 1.0 2.3 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange DUF3087 PF11286.8 EWM25062.1 - 7.2 6.1 8.0 0.52 9.8 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) JAB PF01398.21 EWM25063.1 - 1.6e-34 118.4 0.1 3.1e-34 117.5 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EWM25063.1 - 3e-14 53.4 0.3 5.2e-14 52.6 0.3 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 EWM25063.1 - 1.2e-05 25.0 0.0 2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Terminase_6 PF03237.15 EWM25063.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Terminase-like family PI3_PI4_kinase PF00454.27 EWM25064.1 - 1.9e-47 162.2 0.0 1e-31 110.6 0.0 2.5 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EWM25064.1 - 3.2e-44 150.6 0.0 5.6e-44 149.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 EWM25064.1 - 2.5e-08 33.9 0.0 4.6e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Toprim_N PF08275.11 EWM25065.1 - 1.1e-29 103.0 0.0 2.3e-29 102.1 0.0 1.5 1 0 0 1 1 1 1 DNA primase catalytic core, N-terminal domain zf-CHC2 PF01807.20 EWM25065.1 - 3.8e-29 100.4 0.0 1.2e-28 98.8 0.0 1.8 1 0 0 1 1 1 1 CHC2 zinc finger Toprim_2 PF13155.6 EWM25065.1 - 1.6e-12 47.7 0.0 5.3e-12 46.0 0.0 2.0 1 0 0 1 1 1 1 Toprim-like Toprim_4 PF13662.6 EWM25065.1 - 1.9e-12 47.4 0.0 4.1e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Toprim_3 PF13362.6 EWM25065.1 - 2.5e-05 24.5 0.0 5.2e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Toprim PF01751.22 EWM25065.1 - 0.0019 18.4 0.0 0.0043 17.3 0.0 1.6 1 0 0 1 1 1 1 Toprim domain CTD PF12815.7 EWM25066.1 - 1.4e-09 38.4 21.4 5.8e-08 33.2 7.5 2.5 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.29 EWM25066.1 - 3.6e-09 36.2 15.6 0.00066 19.5 0.0 5.2 5 0 0 5 5 5 3 KOW motif Spt5-NGN PF03439.13 EWM25066.1 - 6.1e-08 32.5 0.4 1.4e-07 31.3 0.4 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 EWM25066.1 - 4.4e-05 24.4 9.6 4.4e-05 24.4 9.6 4.1 3 1 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal Cation_efflux PF01545.21 EWM25067.1 - 3.6e-28 98.7 4.1 4.8e-28 98.3 4.1 1.2 1 0 0 1 1 1 1 Cation efflux family SMC_Nse1 PF07574.13 EWM25068.1 - 7.9e-23 81.4 1.8 2.7e-16 60.0 0.3 2.0 2 0 0 2 2 2 2 Nse1 non-SMC component of SMC5-6 complex RE_MjaI PF09568.10 EWM25068.1 - 0.029 14.2 0.3 0.19 11.5 0.1 1.9 1 1 1 2 2 2 0 MjaI restriction endonuclease TRAF_BIRC3_bd PF16673.5 EWM25068.1 - 0.097 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain Mannitol_dh_C PF08125.13 EWM25069.1 - 0.0013 18.3 0.5 0.15 11.5 0.1 3.1 2 2 1 3 3 3 2 Mannitol dehydrogenase C-terminal domain SF-assemblin PF06705.11 EWM25070.1 - 0.045 13.1 0.1 0.065 12.6 0.1 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin IF-2B PF01008.17 EWM25071.1 - 2e-65 220.8 0.0 2.3e-65 220.6 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family ArfGap PF01412.18 EWM25072.1 - 4.2e-30 104.2 0.0 4.8e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf AbiEi_4 PF13338.6 EWM25072.1 - 0.012 15.8 0.0 0.027 14.6 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin Tubulin PF00091.25 EWM25073.1 - 3e-41 141.8 0.4 4.6e-41 141.2 0.4 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 EWM25073.1 - 4.4e-31 107.1 1.1 2e-30 104.9 0.3 2.3 2 0 0 2 2 2 1 FtsZ family, C-terminal domain WD40 PF00400.32 EWM25073.1 - 1.5e-11 44.6 10.3 0.00086 20.1 0.8 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat NAD_binding_10 PF13460.6 EWM25073.1 - 0.014 15.3 1.0 0.036 13.9 1.0 1.7 1 1 0 1 1 1 0 NAD(P)H-binding Tubulin_2 PF13809.6 EWM25073.1 - 1 8.5 8.5 0.91 8.6 3.7 2.4 1 1 1 2 2 2 0 Tubulin like PSII_Pbs31 PF18240.1 EWM25074.1 - 2.2e-21 76.1 1.1 3.6e-21 75.4 1.1 1.3 1 0 0 1 1 1 1 Photosystem II Psb31 protein AAA_2 PF07724.14 EWM25075.1 - 5.7e-35 120.9 0.0 9.1e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 EWM25075.1 - 1.2e-14 54.9 0.0 1.9e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MCM PF00493.23 EWM25075.1 - 1e-05 24.7 0.1 5.8e-05 22.3 0.1 2.1 2 1 0 2 2 2 1 MCM P-loop domain AAA_22 PF13401.6 EWM25075.1 - 1.1e-05 25.7 0.2 7.5e-05 23.0 0.2 2.1 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EWM25075.1 - 6.9e-05 22.3 0.1 0.00055 19.4 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EWM25075.1 - 7.4e-05 22.8 0.7 0.00062 19.8 0.7 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EWM25075.1 - 7.7e-05 22.5 0.3 0.00096 18.9 0.2 2.4 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 EWM25075.1 - 0.00033 20.4 0.1 0.0041 16.8 0.1 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_33 PF13671.6 EWM25075.1 - 0.0027 17.9 0.0 0.0057 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 EWM25075.1 - 0.0029 17.7 0.0 0.0084 16.2 0.0 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain ABC_tran PF00005.27 EWM25075.1 - 0.0068 16.9 0.1 0.014 15.9 0.0 1.7 2 0 0 2 2 1 1 ABC transporter T2SSE PF00437.20 EWM25075.1 - 0.0095 15.0 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein IstB_IS21 PF01695.17 EWM25075.1 - 0.018 14.8 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.6 EWM25075.1 - 0.019 15.3 0.9 0.056 13.8 0.2 1.9 2 1 0 2 2 1 0 AAA ATPase domain AAA_18 PF13238.6 EWM25075.1 - 0.024 15.2 0.0 0.04 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EWM25075.1 - 0.036 13.6 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DEAD PF00270.29 EWM25075.1 - 0.052 13.3 0.0 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_28 PF13521.6 EWM25075.1 - 0.056 13.7 0.2 0.78 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EWM25075.1 - 0.062 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EWM25075.1 - 0.077 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EWM25075.1 - 0.078 12.9 0.4 0.19 11.7 0.4 1.7 1 1 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 EWM25075.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EWM25075.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Mucin_bdg PF03272.13 EWM25075.1 - 0.15 12.1 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative mucin or carbohydrate-binding module Pkinase PF00069.25 EWM25079.1 - 1.5e-35 122.9 0.0 1.3e-33 116.5 0.0 2.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM25079.1 - 4e-21 75.5 0.0 4.8e-19 68.7 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EWM25079.1 - 0.013 14.3 0.0 0.029 13.1 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase YlzJ PF14035.6 EWM25079.1 - 0.033 14.4 0.0 2 8.7 0.0 2.5 2 0 0 2 2 2 0 YlzJ-like protein APH PF01636.23 EWM25079.1 - 0.091 12.7 0.0 8.2 6.3 0.1 2.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Csm1_N PF18504.1 EWM25079.1 - 1.3 9.4 6.1 5 7.5 0.1 3.2 3 0 0 3 3 3 0 Csm1 N-terminal domain Robl_LC7 PF03259.17 EWM25080.1 - 1.4e-13 50.5 0.0 1.6e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain EbsA PF17255.2 EWM25080.1 - 0.086 13.2 0.0 0.17 12.2 0.0 1.5 2 0 0 2 2 2 0 EbsA-like protein MoaE PF02391.17 EWM25081.1 - 7e-39 132.6 0.1 8.9e-39 132.3 0.1 1.1 1 0 0 1 1 1 1 MoaE protein CTP_transf_like PF01467.26 EWM25082.1 - 2.6e-12 47.1 0.0 4.4e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 EWM25082.1 - 0.13 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 FAD synthetase Rieske_2 PF13806.6 EWM25083.1 - 0.22 11.5 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Rieske-like [2Fe-2S] domain PDZ_2 PF13180.6 EWM25084.1 - 3e-07 30.6 0.0 0.023 15.0 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 EWM25084.1 - 4.4e-07 29.6 0.4 0.014 15.2 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 EWM25084.1 - 4.8e-07 30.0 0.0 0.024 15.0 0.0 2.3 2 0 0 2 2 2 2 PDZ domain Agenet PF05641.12 EWM25084.1 - 0.11 12.9 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 Agenet domain DUF726 PF05277.12 EWM25086.1 - 1.9e-79 267.1 3.1 1.6e-66 224.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF726) Tmemb_14 PF03647.13 EWM25087.1 - 1.3e-18 67.5 5.7 1.5e-18 67.3 5.7 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF4071 PF13281.6 EWM25087.1 - 0.26 10.3 0.0 0.32 10.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) UCH PF00443.29 EWM25089.1 - 2.7e-08 33.6 0.0 3.4e-07 30.0 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DNA_ligase_ZBD PF03119.16 EWM25089.1 - 2.4 8.2 5.4 64 3.7 0.1 3.7 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain RRN3 PF05327.11 EWM25090.1 - 1.2e-64 218.8 0.0 1.8e-46 158.9 0.0 2.8 3 1 0 3 3 3 2 RNA polymerase I specific transcription initiation factor RRN3 Thioredox_DsbH PF03190.15 EWM25091.1 - 1.1e-67 227.1 0.0 1.7e-67 226.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 EWM25091.1 - 1.6e-07 31.4 0.0 3.2e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Glyco_hydro_88 PF07470.13 EWM25091.1 - 0.063 12.4 0.1 0.49 9.4 0.0 2.3 2 1 0 2 2 2 0 Glycosyl Hydrolase Family 88 SPO11_like PF03533.14 EWM25091.1 - 0.25 11.5 2.1 0.62 10.2 0.3 2.6 3 0 0 3 3 3 0 SPO11 homologue Macro PF01661.21 EWM25092.1 - 2.4e-37 127.6 0.0 4.2e-37 126.8 0.0 1.4 1 0 0 1 1 1 1 Macro domain VASt PF16016.5 EWM25093.1 - 2.3e-23 83.3 0.0 3.3e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain PAS_4 PF08448.10 EWM25094.1 - 0.067 13.4 0.0 0.29 11.4 0.0 2.1 2 0 0 2 2 2 0 PAS fold MinC_N PF05209.13 EWM25095.1 - 0.088 12.8 0.0 1.1 9.3 0.0 2.6 2 1 0 2 2 2 0 Septum formation inhibitor MinC, N-terminal domain Secretin_N_2 PF07655.13 EWM25095.1 - 0.2 12.2 0.2 0.44 11.1 0.2 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain eRF1_2 PF03464.15 EWM25096.1 - 6e-42 143.1 0.0 1e-41 142.4 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EWM25096.1 - 2.5e-35 121.4 0.2 4.5e-35 120.5 0.2 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 EWM25096.1 - 1.8e-19 70.0 0.0 3e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 EWM25096.1 - 6.1e-08 33.0 0.0 1.1e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 EWM25096.1 - 7e-06 26.3 0.0 1.2e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 DUF5643 PF18705.1 EWM25096.1 - 0.059 13.4 0.0 0.87 9.6 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5643) COPI_assoc PF08507.10 EWM25099.1 - 3.4e-06 27.1 6.6 5.3e-06 26.5 6.6 1.2 1 0 0 1 1 1 1 COPI associated protein Mito_carr PF00153.27 EWM25100.1 - 3.8e-43 145.3 6.5 1.7e-17 63.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Acetyltransf_1 PF00583.25 EWM25101.1 - 3.7e-07 30.4 0.0 6.7e-07 29.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EWM25101.1 - 7.1e-05 22.8 0.0 0.00014 21.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EWM25101.1 - 7.8e-05 23.0 0.0 0.00037 20.9 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EWM25101.1 - 0.0033 18.1 0.0 0.0058 17.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EWM25101.1 - 0.022 14.8 0.0 0.17 11.9 0.0 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EWM25101.1 - 0.032 14.4 0.0 0.1 12.7 0.0 1.8 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 EWM25101.1 - 0.062 13.3 0.0 0.26 11.3 0.0 2.0 2 0 0 2 2 2 0 FR47-like protein Abhydrolase_3 PF07859.13 EWM25102.1 - 1.5e-16 60.9 0.1 3.1e-16 59.9 0.1 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 EWM25102.1 - 4.5e-13 48.9 0.0 1.3e-12 47.4 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family RRF PF01765.19 EWM25103.1 - 7e-59 198.4 0.5 1.2e-58 197.6 0.1 1.5 1 1 1 2 2 2 1 Ribosome recycling factor SBP_bac_3 PF00497.20 EWM25103.1 - 0.0084 15.6 0.4 0.13 11.7 0.0 2.0 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 JIP_LZII PF16471.5 EWM25103.1 - 1.4 9.2 7.0 0.25 11.5 2.6 2.0 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II HA2 PF04408.23 EWM25104.1 - 2.6e-21 75.9 0.0 2.6e-21 75.9 0.0 4.0 4 1 0 4 4 4 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EWM25104.1 - 3.1e-19 69.1 0.1 6.9e-19 68.0 0.1 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EWM25104.1 - 1.1e-13 51.5 0.0 4e-13 49.7 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EWM25104.1 - 1.8e-07 31.1 0.1 9e-07 28.8 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EWM25104.1 - 0.00012 22.3 0.1 0.00058 20.1 0.1 2.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EWM25104.1 - 0.00098 19.5 0.5 0.0059 16.9 0.2 2.4 3 0 0 3 3 3 1 AAA domain Flavi_DEAD PF07652.14 EWM25104.1 - 0.0018 18.3 0.4 0.012 15.6 0.2 2.2 2 0 0 2 2 2 1 Flavivirus DEAD domain Helicase_RecD PF05127.14 EWM25104.1 - 0.016 15.0 0.2 0.062 13.2 0.0 2.1 2 0 0 2 2 2 0 Helicase T2SSE PF00437.20 EWM25104.1 - 0.023 13.7 0.0 0.053 12.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Calreticulin PF00262.18 EWM25105.1 - 2.3e-85 286.7 15.4 7.9e-62 209.2 0.1 3.1 2 1 1 3 3 3 2 Calreticulin family Pex14_N PF04695.13 EWM25106.1 - 1e-07 32.7 0.0 1.8e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1335 PF07056.11 EWM25106.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1335) NIF PF03031.18 EWM25107.1 - 1.2e-19 70.6 0.0 1.6e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase SNase PF00565.17 EWM25108.1 - 4.4e-61 204.1 0.0 1.4e-14 54.5 0.4 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 EWM25108.1 - 4e-16 59.1 0.0 7.2e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Tudor domain HLH PF00010.26 EWM25109.1 - 3.8e-11 42.8 4.1 7.3e-11 41.9 4.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS PF00989.25 EWM25109.1 - 2e-07 31.0 0.0 4.2e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EWM25109.1 - 2.6e-07 30.9 0.0 1e-06 28.9 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 EWM25109.1 - 1.8e-06 28.1 0.0 4.2e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 PAS domain Sigma70_ner PF04546.13 EWM25109.1 - 0.00075 19.4 2.7 0.0011 18.8 2.7 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region Ribosomal_60s PF00428.19 EWM25109.1 - 0.0017 18.9 14.1 0.02 15.5 6.0 2.5 2 0 0 2 2 2 2 60s Acidic ribosomal protein PAS_8 PF13188.7 EWM25109.1 - 0.005 16.8 0.0 0.012 15.6 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_11 PF14598.6 EWM25109.1 - 0.0078 16.3 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 PAS domain DUF3138 PF11336.8 EWM25109.1 - 0.35 9.4 5.3 0.62 8.6 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Ank_2 PF12796.7 EWM25111.1 - 4e-30 104.2 0.2 3.7e-13 49.9 0.0 3.6 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EWM25111.1 - 2.6e-20 71.9 2.8 0.00061 20.1 0.0 5.8 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 EWM25111.1 - 8.9e-20 70.8 0.2 1.6e-08 34.9 0.0 4.1 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EWM25111.1 - 9.3e-17 60.9 2.1 5.2e-05 23.5 0.0 4.8 3 2 3 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EWM25111.1 - 1.2e-15 56.0 0.3 0.0066 16.9 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat DUF2254 PF10011.9 EWM25111.1 - 0.0032 16.3 0.1 0.0048 15.8 0.1 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2254) adh_short_C2 PF13561.6 EWM25112.1 - 8e-38 130.3 0.0 1e-37 129.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EWM25112.1 - 1.7e-21 76.6 0.0 2.1e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EWM25112.1 - 0.04 13.8 0.1 4.9 7.0 0.0 2.2 2 0 0 2 2 2 0 KR domain Pex14_N PF04695.13 EWM25114.1 - 6e-10 40.0 0.0 6e-10 40.0 0.0 3.2 3 1 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1682 PF07946.14 EWM25114.1 - 0.36 10.0 1.9 1.5 8.0 1.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1682) Nnf1 PF03980.14 EWM25115.1 - 5.3e-07 30.0 4.3 1.1e-06 28.9 4.2 1.6 1 1 0 1 1 1 1 Nnf1 AKAP2_C PF15304.6 EWM25115.1 - 0.0052 16.1 1.7 0.0075 15.6 1.7 1.3 1 0 0 1 1 1 1 A-kinase anchor protein 2 C-terminus Gp-FAR-1 PF05823.12 EWM25115.1 - 0.047 14.0 0.4 0.55 10.6 0.0 2.1 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) ANAPC4_WD40 PF12894.7 EWM25117.1 - 5.5e-06 26.6 0.0 0.03 14.6 0.0 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EWM25117.1 - 0.00026 21.7 0.0 7.4 7.6 0.0 4.7 4 0 0 4 4 4 1 WD domain, G-beta repeat PQQ PF01011.21 EWM25117.1 - 0.12 12.3 0.0 1.2 9.2 0.0 2.6 2 0 0 2 2 2 0 PQQ enzyme repeat LTD PF00932.19 EWM25118.1 - 2.9e-11 43.7 0.0 4.8e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Lamin Tail Domain ThiF PF00899.21 EWM25119.1 - 2.1e-58 197.6 0.0 5.9e-58 196.1 0.0 1.6 2 0 0 2 2 2 1 ThiF family Rhodanese PF00581.20 EWM25119.1 - 1.3e-07 32.1 0.0 8.6e-07 29.4 0.0 2.3 1 1 0 1 1 1 1 Rhodanese-like domain WD40 PF00400.32 EWM25120.1 - 5.6e-51 169.4 5.0 1.7e-07 31.8 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM25120.1 - 5e-18 65.2 0.3 0.00069 19.9 0.1 6.0 3 3 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EWM25120.1 - 4e-06 26.0 0.1 2.7 6.9 0.1 4.9 2 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EWM25120.1 - 6.6e-05 22.9 0.0 2 8.2 0.0 3.1 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 EWM25120.1 - 0.0094 14.3 0.0 1.6 6.9 0.0 2.2 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 EWM25120.1 - 0.02 14.9 0.0 12 6.0 0.0 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 EWM25120.1 - 0.022 13.3 0.0 0.052 12.1 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain Me-amine-dh_H PF06433.11 EWM25120.1 - 0.028 13.3 0.0 0.061 12.2 0.0 1.6 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) nos_propeller PF18764.1 EWM25120.1 - 0.13 12.2 0.1 0.59 10.1 0.0 2.1 2 0 0 2 2 2 0 Nitrous oxide reductase propeller repeat Nup160 PF11715.8 EWM25120.1 - 0.43 9.2 2.2 2.4 6.7 0.8 2.7 3 1 0 3 3 3 0 Nucleoporin Nup120/160 Gly_transf_sug PF04488.15 EWM25121.1 - 0.00011 22.8 0.0 0.00082 20.0 0.0 2.4 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Sulfotransfer_3 PF13469.6 EWM25121.1 - 0.00021 21.8 3.4 1.5 9.1 0.0 4.6 4 1 0 4 4 4 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 EWM25121.1 - 0.0014 18.2 0.0 0.0025 17.3 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase domain MRG PF05712.13 EWM25123.1 - 9.1e-14 51.2 0.0 1.4e-11 44.1 0.0 3.1 2 1 0 2 2 2 2 MRG APG6 PF04111.12 EWM25124.1 - 2.2e-47 161.3 0.0 2.8e-47 161.0 0.0 1.1 1 0 0 1 1 1 1 Apg6 BARA domain DUF3419 PF11899.8 EWM25125.1 - 1.1e-76 258.6 0.2 1.6e-76 258.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 EWM25125.1 - 1e-08 35.2 0.0 2.2e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM25125.1 - 1.3e-08 35.4 0.0 1.2e-07 32.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EWM25125.1 - 1.7e-08 34.1 0.0 3.4e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EWM25125.1 - 3.6e-08 34.0 0.0 2.4e-07 31.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EWM25125.1 - 5.9e-08 33.4 0.0 9e-07 29.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM25125.1 - 1.7e-05 24.6 0.0 4.1e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF2023 PF09633.10 EWM25125.1 - 0.0095 16.1 0.0 0.025 14.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2023) Spc7 PF08317.11 EWM25126.1 - 0.1 11.5 22.8 0.84 8.5 4.1 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4200 PF13863.6 EWM25126.1 - 0.12 12.8 24.1 0.58 10.6 2.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Filament PF00038.21 EWM25126.1 - 0.14 11.7 19.0 0.078 12.5 9.0 2.4 2 0 0 2 2 2 0 Intermediate filament protein KxDL PF10241.9 EWM25126.1 - 0.33 11.3 10.1 3.4 8.0 1.4 2.9 2 0 0 2 2 2 0 Uncharacterized conserved protein ERM PF00769.19 EWM25126.1 - 0.53 10.1 30.0 0.18 11.6 14.7 2.4 2 0 0 2 2 2 0 Ezrin/radixin/moesin family ParB PF08775.10 EWM25126.1 - 2.4 8.6 7.1 3.3 8.2 2.5 2.9 3 1 0 3 3 3 0 ParB family BRE1 PF08647.11 EWM25126.1 - 4.3 7.5 21.0 7.1 6.8 1.7 4.3 2 2 2 4 4 4 0 BRE1 E3 ubiquitin ligase Mod_r PF07200.13 EWM25126.1 - 6.8 6.8 23.3 0.11 12.6 2.1 3.0 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Exonuc_VII_L PF02601.15 EWM25126.1 - 9.9 5.6 16.7 3.4 7.2 5.3 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit VDE PF07137.11 EWM25127.1 - 3.8e-77 259.0 0.0 5.6e-77 258.5 0.0 1.2 1 0 0 1 1 1 1 VDE lipocalin domain Lipocalin PF00061.23 EWM25127.1 - 0.0074 16.5 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_2 PF08212.12 EWM25127.1 - 0.037 14.0 0.1 0.99 9.3 0.0 2.7 3 0 0 3 3 3 0 Lipocalin-like domain NTF2 PF02136.20 EWM25128.1 - 2.3e-18 66.9 0.0 3.5e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain PGA2 PF07543.12 EWM25128.1 - 0.32 11.0 4.1 0.69 9.9 4.1 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 DLEU7 PF15760.5 EWM25128.1 - 1.4 8.4 5.3 2.5 7.5 5.3 1.3 1 0 0 1 1 1 0 Leukemia-associated protein 7 PsbP PF01789.16 EWM25129.1 - 0.1 12.7 0.2 0.35 11.0 0.2 1.8 1 1 0 1 1 1 0 PsbP PHD_2 PF13831.6 EWM25130.1 - 3.8e-10 39.1 4.9 8.8e-10 38.0 0.4 3.5 3 0 0 3 3 3 1 PHD-finger PHD PF00628.29 EWM25130.1 - 1.7e-07 31.0 7.5 1.7e-07 31.0 7.5 3.9 4 1 1 5 5 5 1 PHD-finger Prok-RING_1 PF14446.6 EWM25130.1 - 0.0016 18.3 5.5 0.0016 18.3 5.5 2.6 4 0 0 4 4 4 1 Prokaryotic RING finger family 1 zf-HC5HC2H PF13771.6 EWM25130.1 - 0.0017 18.6 1.8 0.0017 18.6 1.8 3.6 3 0 0 3 3 3 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EWM25130.1 - 0.0023 18.1 16.4 0.0037 17.4 4.1 4.1 3 1 0 3 3 3 1 PHD-zinc-finger like domain FYVE_2 PF02318.16 EWM25130.1 - 0.023 14.9 1.3 0.023 14.9 1.3 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger zf-RRPl_C4 PF17026.5 EWM25130.1 - 0.9 9.7 8.0 4 7.6 8.0 2.1 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-PHD-like PF15446.6 EWM25130.1 - 1.1 8.8 10.8 0.21 11.2 5.9 2.2 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Na_H_Exchanger PF00999.21 EWM25131.1 - 1.2e-39 136.2 24.6 1.6e-39 135.8 24.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family APC_r PF05923.12 EWM25131.1 - 0.024 14.4 0.9 0.064 13.0 0.9 1.7 1 0 0 1 1 1 0 APC repeat PetM PF08041.11 EWM25131.1 - 0.44 10.2 7.5 0.63 9.7 0.4 3.5 3 0 0 3 3 3 0 PetM family of cytochrome b6f complex subunit 7 Adeno_E3_CR2 PF02439.15 EWM25131.1 - 5.2 6.9 6.5 1.3 8.8 0.6 2.7 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 CAF1A PF12253.8 EWM25132.1 - 2.1e-21 75.9 6.7 2.1e-21 75.9 6.7 3.0 4 0 0 4 4 4 1 Chromatin assembly factor 1 subunit A TAF4 PF05236.14 EWM25132.1 - 0.00034 20.5 10.8 0.00034 20.5 10.8 1.9 2 0 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family CAF-1_p150 PF11600.8 EWM25132.1 - 2.4 7.9 29.5 4.6 6.9 29.5 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1015 PF06245.11 EWM25133.1 - 7.7e-121 403.7 0.0 8.7e-121 403.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1015) Ribosomal_S8e PF01201.22 EWM25134.1 - 1.1e-54 184.3 1.3 1.5e-54 183.9 1.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e TALPID3 PF15324.6 EWM25134.1 - 0.0023 15.7 0.3 0.0026 15.6 0.3 1.0 1 0 0 1 1 1 1 Hedgehog signalling target pKID PF02173.17 EWM25134.1 - 0.4 10.2 3.8 1.1 8.8 3.8 1.6 1 0 0 1 1 1 0 pKID domain ADH_zinc_N PF00107.26 EWM25135.1 - 0.0073 16.3 0.3 0.015 15.3 0.3 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FliMN_C PF01052.20 EWM25135.1 - 0.0097 15.9 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 Type III flagellar switch regulator (C-ring) FliN C-term HSP33 PF01430.19 EWM25135.1 - 0.047 13.1 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 Hsp33 protein ADH_N PF08240.12 EWM25135.1 - 0.076 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 EWM25136.1 - 7.1e-27 94.1 0.0 1.2e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EWM25136.1 - 3.2e-19 69.4 0.0 5.2e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 EWM25136.1 - 3.3e-09 36.5 0.0 2.3e-08 33.8 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) F-actin_cap_A PF01267.17 EWM25137.1 - 3.2e-44 151.4 0.2 1.3e-37 129.7 0.2 2.0 1 1 1 2 2 2 2 F-actin capping protein alpha subunit Octopine_DH PF02317.17 EWM25138.1 - 1.9e-38 131.9 0.0 2.7e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Pyr_redox_2 PF07992.14 EWM25138.1 - 0.016 14.4 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PaO PF08417.12 EWM25140.1 - 3.9e-17 62.2 0.0 9.3e-17 61.0 0.0 1.6 1 0 0 1 1 1 1 Pheophorbide a oxygenase Rieske PF00355.26 EWM25140.1 - 2e-16 59.7 0.0 3.6e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 EWM25140.1 - 1.6e-05 24.8 0.0 4.5e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain SSF PF00474.17 EWM25140.1 - 0.28 10.0 0.0 0.39 9.5 0.0 1.1 1 0 0 1 1 1 0 Sodium:solute symporter family LRR_6 PF13516.6 EWM25141.1 - 4.2e-11 42.0 12.7 0.066 13.3 0.1 7.1 7 0 0 7 7 7 4 Leucine Rich repeat LRR_4 PF12799.7 EWM25141.1 - 5.7e-05 23.4 6.2 0.037 14.4 0.2 5.1 4 2 2 6 6 6 2 Leucine Rich repeats (2 copies) LRR_2 PF07723.13 EWM25141.1 - 0.021 15.5 4.9 16 6.4 0.0 4.9 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_8 PF13855.6 EWM25141.1 - 0.038 13.7 11.2 0.93 9.3 1.2 5.5 4 2 0 4 4 4 0 Leucine rich repeat ArenaCapSnatch PF17296.2 EWM25141.1 - 0.16 11.4 0.1 0.27 10.6 0.1 1.3 1 0 0 1 1 1 0 Arenavirus cap snatching domain ATP-synt_ab PF00006.25 EWM25142.1 - 7.6e-61 205.5 0.0 1.2e-60 204.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EWM25142.1 - 2.5e-19 69.6 2.3 5e-19 68.6 2.3 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_19 PF13245.6 EWM25142.1 - 0.058 13.7 1.3 0.31 11.4 0.2 2.3 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 EWM25142.1 - 0.058 12.7 1.7 0.13 11.6 1.7 1.6 1 0 0 1 1 1 0 KaiC RnfC_N PF13375.6 EWM25142.1 - 0.061 13.3 0.2 0.29 11.1 0.2 2.1 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain NB-ARC PF00931.22 EWM25142.1 - 0.11 11.7 0.4 0.25 10.5 0.4 1.5 1 0 0 1 1 1 0 NB-ARC domain Sulfotransfer_1 PF00685.27 EWM25143.1 - 4.6e-10 39.4 0.2 3.5e-09 36.5 0.2 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EWM25143.1 - 1.6e-08 35.2 0.9 1.6e-07 31.9 0.1 2.2 1 1 1 2 2 2 1 Sulfotransferase family FKBP_C PF00254.28 EWM25144.1 - 2.9e-31 107.6 0.0 4.3e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase WCOR413 PF05562.11 EWM25144.1 - 0.13 12.2 0.2 0.19 11.6 0.2 1.2 1 0 0 1 1 1 0 Cold acclimation protein WCOR413 Vps35 PF03635.17 EWM25145.1 - 5e-254 845.2 0.0 5.8e-254 845.0 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Rv2175c_C PF18367.1 EWM25146.1 - 0.048 13.7 0.0 0.17 12.0 0.0 1.9 1 0 0 1 1 1 0 Rv2175c C-terminal domain of unknown function Peptidase_M41 PF01434.18 EWM25146.1 - 0.058 13.2 0.6 0.1 12.4 0.0 1.6 2 0 0 2 2 2 0 Peptidase family M41 Rv2175c_C PF18367.1 EWM25147.1 - 0.0012 18.8 0.0 0.0043 17.1 0.0 1.9 1 0 0 1 1 1 1 Rv2175c C-terminal domain of unknown function Peptidase_M41 PF01434.18 EWM25147.1 - 0.05 13.4 0.5 0.097 12.5 0.0 1.6 2 0 0 2 2 2 0 Peptidase family M41 UCH PF00443.29 EWM25148.1 - 6.6e-47 160.2 0.0 8.3e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EWM25148.1 - 2.2e-12 47.2 0.0 1.3e-11 44.7 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EWM25148.1 - 2.2e-06 27.3 0.0 4.4e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Peptidase_C98 PF15499.6 EWM25148.1 - 0.0098 15.4 0.0 0.13 11.7 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase FCP1_C PF09309.10 EWM25148.1 - 0.047 13.6 0.0 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 FCP1, C-terminal Ubiquitin_2 PF14560.6 EWM25148.1 - 0.064 13.7 0.0 0.59 10.6 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain UIM PF02809.20 EWM25148.1 - 0.73 9.9 12.7 0.053 13.4 6.9 2.3 2 0 0 2 2 2 0 Ubiquitin interaction motif RVT_1 PF00078.27 EWM25149.1 - 7.6e-05 22.3 0.0 9.4e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MutS_V PF00488.21 EWM25150.1 - 5e-73 245.2 0.0 7.8e-73 244.5 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EWM25150.1 - 5.7e-31 108.2 0.4 9.3e-31 107.5 0.4 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EWM25150.1 - 6.6e-30 103.7 0.0 1.2e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.18 EWM25150.1 - 3.9e-13 49.5 0.2 3.9e-13 49.5 0.2 1.7 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.17 EWM25150.1 - 1.9e-08 34.7 0.0 9.1e-08 32.5 0.0 2.2 2 0 0 2 2 2 1 MutS domain II 53-BP1_Tudor PF09038.10 EWM25150.1 - 0.071 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor CHASE3 PF05227.13 EWM25150.1 - 2.1 8.3 4.9 4 7.3 1.3 2.7 2 0 0 2 2 2 0 CHASE3 domain DZR PF12773.7 EWM25151.1 - 0.076 13.1 4.9 0.41 10.7 5.0 2.2 1 1 0 1 1 1 0 Double zinc ribbon Rubredoxin PF00301.20 EWM25151.1 - 3.5 7.7 10.8 0.3 11.1 0.8 3.3 3 0 0 3 3 3 0 Rubredoxin PEPcase PF00311.17 EWM25152.1 - 2.9e-263 875.7 0.2 3.7e-263 875.3 0.2 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.6 EWM25152.1 - 7.3e-05 21.5 0.0 0.00025 19.7 0.0 1.9 1 1 0 1 1 1 1 Phosphoenolpyruvate carboxylase RdDM_RDM1 PF09187.10 EWM25152.1 - 0.17 11.9 0.5 8.4 6.5 0.1 2.9 2 0 0 2 2 2 0 RNA-directed DNA methylation 1 Mt_ATP-synt_B PF05405.14 EWM25153.1 - 3.9e-13 49.4 1.9 6.4e-13 48.6 1.9 1.4 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) GRAM PF02893.20 EWM25155.1 - 7.5e-16 58.0 0.3 1.1e-15 57.5 0.3 1.2 1 0 0 1 1 1 1 GRAM domain bPH_3 PF14470.6 EWM25155.1 - 0.24 11.8 0.0 0.39 11.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial PH domain Lipase_3 PF01764.25 EWM25157.1 - 2.3e-32 111.8 0.0 3.2e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 EWM25157.1 - 0.00024 20.7 0.0 0.00052 19.6 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 EWM25157.1 - 0.0024 18.5 7.4 0.014 16.0 7.4 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EWM25157.1 - 0.024 13.9 0.0 0.036 13.3 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EWM25157.1 - 0.055 13.1 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 EWM25157.1 - 0.055 13.2 0.0 0.083 12.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Thioesterase PF00975.20 EWM25157.1 - 0.15 12.2 0.1 0.2 11.7 0.1 1.2 1 0 0 1 1 1 0 Thioesterase domain Tmemb_14 PF03647.13 EWM25159.1 - 2.4 8.9 9.7 0.091 13.5 1.3 2.6 1 1 1 2 2 2 0 Transmembrane proteins 14C Pkinase PF00069.25 EWM25160.1 - 1.5e-50 172.0 0.0 2e-50 171.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM25160.1 - 1.6e-31 109.5 0.0 2.3e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EWM25160.1 - 1.1e-09 37.6 0.0 1.8e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EWM25160.1 - 0.0056 16.6 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EWM25160.1 - 0.032 13.6 0.0 0.08 12.2 0.0 1.6 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 EWM25160.1 - 0.034 13.5 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RrnaAD PF00398.20 EWM25161.1 - 4.3e-05 22.7 0.0 6.5e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 EWM25161.1 - 0.0019 18.2 0.0 0.0035 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EWM25161.1 - 0.02 14.6 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF3402 PF11882.8 EWM25161.1 - 0.032 13.3 0.0 0.05 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) bZIP_1 PF00170.21 EWM25162.1 - 2e-07 31.0 9.8 2e-07 31.0 9.8 2.4 2 0 0 2 2 2 1 bZIP transcription factor UPF0242 PF06785.11 EWM25162.1 - 0.02 15.0 2.2 0.02 15.0 2.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Metal_resist PF13801.6 EWM25162.1 - 0.07 13.3 0.1 0.07 13.3 0.1 2.6 2 1 0 2 2 2 0 Heavy-metal resistance DUF4156 PF13698.6 EWM25162.1 - 0.58 10.5 2.7 4.8 7.6 0.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4156) DUF4376 PF14301.6 EWM25162.1 - 1.5 9.2 8.6 0.19 12.1 3.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4376) bZIP_2 PF07716.15 EWM25162.1 - 1.7 8.8 17.1 0.051 13.7 9.9 2.2 2 0 0 2 2 2 0 Basic region leucine zipper Ion_trans PF00520.31 EWM25163.1 - 1.1e-12 47.7 3.8 1.1e-12 47.7 3.8 2.6 2 1 0 2 2 2 1 Ion transport protein Glycos_trans_3N PF02885.17 EWM25163.1 - 0.15 11.9 0.0 0.52 10.2 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain Pkinase PF00069.25 EWM25166.1 - 4.8e-50 170.4 0.0 8.7e-50 169.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM25166.1 - 1.5e-24 86.7 0.0 2.1e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EWM25166.1 - 0.0085 16.0 0.9 0.014 15.3 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EWM25166.1 - 0.011 15.4 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Cyanate_lyase PF02560.14 EWM25168.1 - 1.4e-10 40.9 0.0 3.2e-10 39.7 0.0 1.6 2 0 0 2 2 2 1 Cyanate lyase C-terminal domain HTH_24 PF13412.6 EWM25168.1 - 0.051 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_3 PF01381.22 EWM25168.1 - 0.065 13.3 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix Rrf2 PF02082.20 EWM25168.1 - 0.12 12.7 0.1 0.19 12.1 0.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator Peptidase_S8 PF00082.22 EWM25172.1 - 1.7e-36 126.1 0.0 2.4e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 Subtilase family BTK PF00779.19 EWM25177.1 - 1.1e-06 28.3 5.7 0.00026 20.7 2.5 2.3 2 0 0 2 2 2 2 BTK motif CHORD PF04968.12 EWM25177.1 - 0.23 12.2 4.6 3.9 8.3 4.6 2.2 1 1 0 1 1 1 0 CHORD Dynein_attach_N PF15867.5 EWM25179.1 - 2.5e-18 65.8 1.0 5.6e-18 64.7 0.3 1.9 2 0 0 2 2 2 1 Dynein attachment factor N-terminus RPAP3_C PF13877.6 EWM25179.1 - 0.0072 16.8 0.0 0.06 13.9 0.0 2.4 2 1 1 3 3 3 1 Potential Monad-binding region of RPAP3 Ion_trans PF00520.31 EWM25180.1 - 1.5e-09 37.5 14.6 3.3e-09 36.3 14.6 1.5 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EWM25180.1 - 1.8e-09 37.5 0.8 1.8e-09 37.5 0.8 2.4 2 1 0 2 2 2 1 Ion channel E1-E2_ATPase PF00122.20 EWM25181.1 - 3.8e-46 156.9 0.1 3.8e-46 156.9 0.1 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 EWM25181.1 - 9.6e-11 41.2 0.0 1.8e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EWM25181.1 - 0.0039 17.2 0.0 0.007 16.4 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Phage_holin_3_6 PF07332.11 EWM25181.1 - 5.2 7.2 17.5 1.2 9.1 2.5 2.5 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Flavokinase PF01687.17 EWM25182.1 - 2.1e-30 105.3 0.0 3.2e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 Riboflavin kinase Methyltransf_25 PF13649.6 EWM25182.1 - 2.9e-05 24.7 0.0 5.1e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM25182.1 - 0.00018 22.1 0.0 0.00042 20.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM25182.1 - 0.00047 20.0 0.0 0.00067 19.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EWM25182.1 - 0.018 14.9 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EWM25182.1 - 0.028 15.2 0.0 0.041 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 EWM25182.1 - 0.2 11.0 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Flavokinase PF01687.17 EWM25183.1 - 2.1e-30 105.3 0.0 3.2e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 Riboflavin kinase Methyltransf_25 PF13649.6 EWM25183.1 - 2.9e-05 24.7 0.0 5.1e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM25183.1 - 0.00018 22.1 0.0 0.00042 20.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM25183.1 - 0.00047 20.0 0.0 0.00067 19.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EWM25183.1 - 0.018 14.9 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EWM25183.1 - 0.028 15.2 0.0 0.041 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 EWM25183.1 - 0.2 11.0 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Cation_ATPase_C PF00689.21 EWM25184.1 - 0.0029 17.3 0.4 0.0045 16.7 0.4 1.3 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Zn_clus PF00172.18 EWM25186.1 - 1e-06 28.8 8.6 2.1e-06 27.7 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 EWM25188.1 - 2.9e-08 33.7 9.0 6.1e-08 32.7 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUZ PF12752.7 EWM25188.1 - 0.23 12.3 0.2 0.23 12.3 0.2 2.2 2 0 0 2 2 2 0 SUZ domain Inhibitor_I68 PF10468.9 EWM25188.1 - 0.54 10.7 5.7 0.5 10.8 0.2 2.6 1 1 1 2 2 2 0 Carboxypeptidase inhibitor I68 Zn_clus PF00172.18 EWM25191.1 - 4.4e-07 29.9 15.9 9.4e-07 28.9 15.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 EWM25191.1 - 0.92 9.4 11.4 1.4 8.8 11.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF755 PF05501.11 EWM25191.1 - 2.1 8.7 12.1 0.035 14.4 4.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF755) MMR1 PF08505.10 EWM25191.1 - 2.8 8.2 6.7 4.5 7.5 5.1 2.0 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Cation_ATPase_C PF00689.21 EWM25192.1 - 6.1e-13 48.9 0.0 7.5e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Pkinase PF00069.25 EWM25194.1 - 2.1e-64 217.4 0.0 2.4e-64 217.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM25194.1 - 1.3e-33 116.3 0.0 1.9e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EWM25194.1 - 0.00085 19.3 0.8 0.0013 18.7 0.1 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EWM25194.1 - 0.00088 18.3 0.1 0.0012 17.9 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EWM25194.1 - 0.012 15.0 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 EWM25194.1 - 0.13 11.6 1.2 0.51 9.7 1.2 1.9 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3149 PF11346.8 EWM25199.1 - 0.99 9.1 0.0 0.99 9.1 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3149) Histone PF00125.24 EWM25200.1 - 9.9e-53 178.0 2.0 1.3e-52 177.6 2.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EWM25200.1 - 0.00013 22.3 0.0 0.00025 21.4 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EWM25200.1 - 0.00025 21.1 0.2 0.00073 19.6 0.1 1.8 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EWM25200.1 - 0.00078 20.0 2.2 0.0013 19.3 2.2 1.3 1 0 0 1 1 1 1 PCNA-associated factor histone like domain TFIID-31kDa PF02291.15 EWM25200.1 - 0.06 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 EWM25200.1 - 0.068 13.5 0.2 0.54 10.6 0.0 2.2 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TIL PF01826.17 EWM25201.1 - 0.00011 22.3 14.0 0.00018 21.7 14.0 1.3 1 0 0 1 1 1 1 Trypsin Inhibitor like cysteine rich domain TIL PF01826.17 EWM25202.1 - 7.2e-05 23.0 14.0 0.00012 22.3 14.0 1.3 1 0 0 1 1 1 1 Trypsin Inhibitor like cysteine rich domain FtsJ PF01728.19 EWM25206.1 - 1.2e-10 41.7 0.0 1.9e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 EWM25206.1 - 0.0012 18.7 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM25206.1 - 0.0042 17.8 0.0 0.0095 16.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EWM25207.1 - 1.7e-05 25.0 0.0 2.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase SSF PF00474.17 EWM25208.1 - 1.4e-18 67.0 30.0 2.3e-18 66.3 30.0 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family HhH-GPD PF00730.25 EWM25209.1 - 3.2e-14 53.3 0.0 7.6e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein OGG_N PF07934.12 EWM25209.1 - 0.02 15.0 0.7 0.1 12.7 0.0 2.2 2 1 0 2 2 2 0 8-oxoguanine DNA glycosylase, N-terminal domain HHH PF00633.23 EWM25209.1 - 0.031 14.1 0.1 0.21 11.5 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF4604 PF15377.6 EWM25209.1 - 1.8 9.0 12.7 2.6 8.5 12.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) SP_C-Propep PF08999.10 EWM25210.1 - 0.011 15.5 1.7 0.012 15.4 1.7 1.2 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide DUF3311 PF11755.8 EWM25211.1 - 0.012 15.5 8.0 4.5 7.3 0.1 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF3311) DUF3796 PF12676.7 EWM25212.1 - 0.46 10.9 4.4 0.18 12.2 1.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) ABC_membrane PF00664.23 EWM25213.1 - 4e-14 52.9 0.1 8.2e-14 51.9 0.1 1.4 1 1 1 2 2 2 1 ABC transporter transmembrane region HPP PF04982.13 EWM25213.1 - 0.28 11.4 10.7 2.2 8.5 2.3 2.6 1 1 1 2 2 2 0 HPP family ABC_tran PF00005.27 EWM25214.1 - 3.1e-08 34.2 0.0 4e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 ABC transporter FHA PF00498.26 EWM25215.1 - 3.3e-11 43.4 0.0 5.1e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EWM25215.1 - 4e-06 27.1 0.0 1.5e-05 25.2 0.0 1.8 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain SDA1 PF05285.12 EWM25216.1 - 0.00015 21.3 4.4 0.00015 21.3 4.4 1.9 2 0 0 2 2 2 1 SDA1 Nucleo_P87 PF07267.11 EWM25216.1 - 0.0026 16.7 10.2 0.0036 16.2 10.2 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus capsid protein P87 DUF2052 PF09747.9 EWM25216.1 - 0.0027 17.8 10.6 0.0053 16.9 10.6 1.5 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) NACHT_N PF17100.5 EWM25216.1 - 0.016 15.1 1.3 0.082 12.7 1.3 2.0 1 1 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase Radial_spoke PF04712.12 EWM25216.1 - 0.022 13.7 8.4 0.03 13.3 8.4 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein DUF1840 PF08895.11 EWM25216.1 - 0.025 14.9 4.6 0.058 13.7 4.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) CDC45 PF02724.14 EWM25216.1 - 0.028 12.7 8.5 0.037 12.3 8.5 1.1 1 0 0 1 1 1 0 CDC45-like protein FmiP_Thoc5 PF09766.9 EWM25216.1 - 0.035 13.4 10.6 0.057 12.7 10.6 1.2 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 RP-C_C PF11800.8 EWM25216.1 - 0.04 14.0 2.9 0.08 13.0 2.9 1.5 1 0 0 1 1 1 0 Replication protein C C-terminal region Eapp_C PF10238.9 EWM25216.1 - 0.047 13.8 5.1 0.082 13.0 5.1 1.4 1 0 0 1 1 1 0 E2F-associated phosphoprotein PBP1_TM PF14812.6 EWM25216.1 - 0.052 13.9 6.3 0.097 13.0 6.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DDHD PF02862.17 EWM25216.1 - 0.053 13.7 2.3 0.069 13.3 2.3 1.3 1 0 0 1 1 1 0 DDHD domain DUF5523 PF17661.1 EWM25216.1 - 0.067 12.9 13.0 0.11 12.1 13.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5523) DUF913 PF06025.12 EWM25216.1 - 0.12 11.3 3.9 0.19 10.6 3.9 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NOA36 PF06524.12 EWM25216.1 - 0.14 11.5 11.1 0.2 11.0 11.1 1.2 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 EWM25216.1 - 0.15 12.1 10.8 0.26 11.3 10.8 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal RNA_pol_3_Rpc31 PF11705.8 EWM25216.1 - 0.22 11.8 12.6 0.43 10.8 12.6 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CDC27 PF09507.10 EWM25216.1 - 0.24 10.8 14.2 0.35 10.2 14.2 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 HA2 PF04408.23 EWM25216.1 - 0.25 11.6 1.8 0.58 10.5 1.8 1.6 1 0 0 1 1 1 0 Helicase associated domain (HA2) Pinin_SDK_memA PF04696.13 EWM25216.1 - 0.27 11.3 15.6 0.64 10.1 15.6 1.6 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region Nop14 PF04147.12 EWM25216.1 - 0.28 9.4 14.0 0.44 8.7 14.0 1.2 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.6 EWM25216.1 - 0.29 10.8 10.7 0.77 9.4 10.7 1.7 1 0 0 1 1 1 0 FAM176 family DUF4637 PF15470.6 EWM25216.1 - 0.3 10.8 10.7 0.58 9.9 10.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Connexin PF00029.19 EWM25216.1 - 0.44 10.3 4.5 0.68 9.6 4.5 1.3 1 0 0 1 1 1 0 Connexin DNA_pol_phi PF04931.13 EWM25216.1 - 0.45 8.6 19.1 0.74 7.8 19.1 1.3 1 0 0 1 1 1 0 DNA polymerase phi RPN2_C PF18004.1 EWM25216.1 - 0.54 10.2 11.7 0.9 9.4 11.7 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CENP-B_dimeris PF09026.10 EWM25216.1 - 0.58 10.6 9.2 1.6 9.2 9.2 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2457 PF10446.9 EWM25216.1 - 0.59 9.2 13.7 1.2 8.2 12.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) RNA_pol_Rpc4 PF05132.14 EWM25216.1 - 0.82 10.1 4.3 1.6 9.1 4.3 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 RR_TM4-6 PF06459.12 EWM25216.1 - 0.9 9.3 12.7 1.5 8.5 12.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pox_Ag35 PF03286.14 EWM25216.1 - 1.2 8.8 10.5 2.1 8.1 10.5 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Myc_N PF01056.18 EWM25216.1 - 1.3 8.9 13.0 2.6 7.9 13.0 1.5 1 0 0 1 1 1 0 Myc amino-terminal region TRAP_alpha PF03896.16 EWM25216.1 - 1.4 8.1 10.2 2.1 7.5 10.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Paf1 PF03985.13 EWM25216.1 - 1.5 7.8 18.1 2.2 7.2 18.1 1.2 1 0 0 1 1 1 0 Paf1 V_ATPase_I PF01496.19 EWM25216.1 - 1.8 6.4 4.5 2.1 6.2 4.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cnd2 PF05786.14 EWM25216.1 - 1.8 7.1 11.3 2.4 6.7 11.3 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 Presenilin PF01080.17 EWM25216.1 - 1.9 7.2 9.0 2.8 6.6 9.0 1.2 1 0 0 1 1 1 0 Presenilin DUF4820 PF16091.5 EWM25216.1 - 2.1 7.6 9.7 3.5 6.9 9.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) SMN PF06003.12 EWM25216.1 - 2.5 7.3 5.3 4 6.6 5.3 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) FAM178 PF14816.6 EWM25216.1 - 2.7 6.9 7.8 5.3 5.9 7.8 1.5 1 0 0 1 1 1 0 Family of unknown function, FAM178 DUF4746 PF15928.5 EWM25216.1 - 3.2 7.1 18.1 4.9 6.5 18.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF1682 PF07946.14 EWM25216.1 - 3.5 6.8 11.7 5.1 6.2 11.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) ANAPC15 PF15243.6 EWM25216.1 - 3.6 8.1 19.4 7.7 7.0 19.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 eIF3_subunit PF08597.10 EWM25216.1 - 4.2 7.2 18.0 11 5.9 16.0 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit TFB6 PF17110.5 EWM25216.1 - 7.3 6.3 9.3 16 5.2 9.3 1.6 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH PPP4R2 PF09184.11 EWM25216.1 - 7.4 6.1 17.7 13 5.2 17.7 1.4 1 0 0 1 1 1 0 PPP4R2 p450 PF00067.22 EWM25219.1 - 0.0017 17.2 0.0 0.002 16.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3326 PF11805.8 EWM25222.1 - 6.5e-126 419.8 0.1 8.3e-126 419.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3326) ThiF PF00899.21 EWM25223.1 - 6e-61 205.9 0.0 1e-60 205.1 0.0 1.3 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 EWM25223.1 - 3.2e-14 53.3 0.0 5.8e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 EWM25223.1 - 3.3e-08 33.8 0.0 2.3e-05 24.5 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Sacchrp_dh_NADP PF03435.18 EWM25223.1 - 0.00076 19.8 0.8 0.003 17.8 0.9 1.9 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 EWM25223.1 - 0.0013 19.1 0.2 0.0081 16.6 0.2 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 EWM25223.1 - 0.017 15.2 0.0 0.029 14.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase CRT-like PF08627.10 EWM25227.1 - 7.1e-63 212.6 8.2 1.7e-62 211.3 8.2 1.5 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like SLC35F PF06027.12 EWM25227.1 - 1.7e-05 24.5 3.1 1.7e-05 24.5 3.1 1.5 2 0 0 2 2 2 1 Solute carrier family 35 UAA PF08449.11 EWM25227.1 - 0.00022 20.5 12.1 0.00039 19.7 12.1 1.4 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 EWM25227.1 - 0.00042 20.5 10.9 0.00042 20.5 10.9 2.6 2 1 0 2 2 2 1 EamA-like transporter family PUNUT PF16913.5 EWM25227.1 - 0.057 12.6 10.0 0.013 14.7 3.0 2.2 2 0 0 2 2 2 0 Purine nucleobase transmembrane transport TMEM171 PF15471.6 EWM25227.1 - 0.091 11.7 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 CENP-B_dimeris PF09026.10 EWM25227.1 - 0.14 12.5 2.3 0.25 11.8 2.3 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ribosomal_60s PF00428.19 EWM25227.1 - 6.9 7.3 11.3 14 6.4 11.3 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein DAGK_acc PF00609.19 EWM25228.1 - 2.9e-45 154.5 0.0 6.7e-45 153.3 0.0 1.6 2 0 0 2 2 2 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 EWM25228.1 - 1e-21 76.8 0.0 1.8e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DAGK_acc PF00609.19 EWM25229.1 - 1.8e-26 93.4 0.0 5.1e-26 91.9 0.0 1.7 2 0 0 2 2 2 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 EWM25229.1 - 7.3e-22 77.3 0.0 1.3e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Syntaxin-6_N PF09177.11 EWM25231.1 - 0.037 14.6 0.5 0.54 10.9 0.4 2.4 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Baculo_PEP_C PF04513.12 EWM25231.1 - 0.11 12.5 1.6 0.21 11.6 0.1 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 EWM25231.1 - 8.7 6.5 6.9 32 4.7 0.2 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family GBP PF02263.19 EWM25232.1 - 3.1e-31 108.6 0.0 5.8e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 EWM25232.1 - 0.081 13.0 0.0 0.24 11.5 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF1771 PF08590.10 EWM25232.1 - 0.11 12.9 0.2 0.11 12.9 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) AAA_22 PF13401.6 EWM25232.1 - 0.11 12.7 0.0 0.38 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain SURNod19 PF07712.12 EWM25233.1 - 1.3e-05 24.2 0.3 0.052 12.3 0.0 3.5 3 1 1 4 4 4 3 Stress up-regulated Nod 19 Pterin_4a PF01329.19 EWM25234.1 - 8e-26 90.0 0.0 1.2e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Hypoth_Ymh PF09509.10 EWM25235.1 - 0.043 13.7 0.0 0.091 12.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (Hypoth_ymh) C1_1 PF00130.22 EWM25236.1 - 9.9e-10 38.2 10.3 4.6e-08 32.8 2.1 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PRT_C PF08372.10 EWM25236.1 - 2.7e-07 30.4 0.1 0.021 14.6 0.0 2.3 2 0 0 2 2 2 2 Plant phosphoribosyltransferase C-terminal C2 PF00168.30 EWM25236.1 - 3.3e-05 24.1 0.0 0.00042 20.6 0.0 2.4 2 0 0 2 2 2 1 C2 domain Pex24p PF06398.11 EWM25236.1 - 3.8e-05 22.8 0.1 0.13 11.2 0.0 2.3 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin C1_2 PF03107.16 EWM25236.1 - 0.00021 21.5 8.3 0.0048 17.2 2.4 2.4 2 0 0 2 2 2 2 C1 domain Herpes_UL32 PF06070.11 EWM25236.1 - 0.087 10.6 7.1 0.15 9.8 7.1 1.2 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 zf-RING_9 PF13901.6 EWM25236.1 - 0.23 11.4 4.8 6.2 6.7 1.1 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon zf-HIT PF04438.16 EWM25236.1 - 0.63 10.0 4.0 4 7.4 0.3 2.6 2 0 0 2 2 2 0 HIT zinc finger PHD_2 PF13831.6 EWM25236.1 - 3 7.5 6.6 1.9 8.1 0.6 2.5 2 0 0 2 2 2 0 PHD-finger C1_1 PF00130.22 EWM25237.1 - 2.4e-08 33.7 2.1 4e-08 33.0 2.1 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PRT_C PF08372.10 EWM25237.1 - 2.1e-07 30.8 0.1 0.018 14.8 0.0 2.3 2 0 0 2 2 2 2 Plant phosphoribosyltransferase C-terminal C2 PF00168.30 EWM25237.1 - 4e-07 30.3 0.0 9.6e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain Pex24p PF06398.11 EWM25237.1 - 3.1e-05 23.1 0.1 0.11 11.4 0.0 2.2 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin C1_2 PF03107.16 EWM25237.1 - 0.0023 18.2 2.4 0.0041 17.4 2.4 1.4 1 0 0 1 1 1 1 C1 domain Herpes_UL32 PF06070.11 EWM25237.1 - 0.073 10.8 7.1 0.13 10.0 7.1 1.3 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 zf-RING-like PF08746.11 EWM25237.1 - 1.8 8.9 3.8 3.6 8.0 3.8 1.5 1 0 0 1 1 1 0 RING-like domain ArfGap PF01412.18 EWM25238.1 - 0.041 14.0 0.2 0.041 14.0 0.2 1.5 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf DUF2834 PF11196.8 EWM25239.1 - 0.31 11.4 3.3 2 8.8 3.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2834) MORN PF02493.20 EWM25240.1 - 1.9e-75 244.5 100.8 5.9e-09 35.3 2.0 15.9 16 0 0 16 16 16 15 MORN repeat DUF3048_C PF17479.2 EWM25240.1 - 0.0054 17.1 31.6 1.9 8.9 0.5 7.4 2 2 5 7 7 7 4 Protein of unknown function (DUF3048) C-terminal domain FKBP_C PF00254.28 EWM25243.1 - 1.7e-30 105.2 0.1 5.1e-30 103.6 0.0 1.8 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase SNAP PF14938.6 EWM25243.1 - 0.13 11.7 0.6 0.17 11.3 0.6 1.1 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP FKBP_C PF00254.28 EWM25244.1 - 1.7e-30 105.2 0.1 5.1e-30 103.6 0.0 1.8 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase SNAP PF14938.6 EWM25244.1 - 0.13 11.7 0.6 0.17 11.3 0.6 1.1 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP DUF3512 PF12024.8 EWM25245.1 - 1.8 8.0 9.5 2 7.8 9.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3512) DUF4554 PF15091.6 EWM25245.1 - 2.6 6.9 13.8 2.9 6.7 13.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Pro_isomerase PF00160.21 EWM25247.1 - 2.1e-53 180.8 0.1 3e-53 180.3 0.1 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 EWM25247.1 - 0.00052 19.9 0.3 0.0012 18.8 0.3 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 EWM25247.1 - 0.00086 19.3 0.1 0.0022 18.1 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 EWM25247.1 - 0.0025 17.6 0.1 0.0046 16.7 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 EWM25247.1 - 0.0065 16.6 0.6 0.011 15.9 0.6 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 EWM25247.1 - 0.029 15.0 3.1 0.049 14.3 3.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat IF-2 PF11987.8 EWM25249.1 - 6.5e-07 29.4 0.0 7.8e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Translation-initiation factor 2 RhlB PF12300.8 EWM25249.1 - 0.094 12.9 5.3 0.13 12.4 5.3 1.2 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB zf-Nse PF11789.8 EWM25252.1 - 5.3e-08 32.6 0.6 7.5e-08 32.1 0.6 1.2 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EWM25252.1 - 0.001 19.0 0.1 0.0016 18.4 0.1 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EWM25252.1 - 0.0035 17.1 0.5 0.0048 16.7 0.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RAG1 PF10426.9 EWM25252.1 - 0.049 13.8 0.4 0.088 13.0 0.4 1.5 1 0 0 1 1 1 0 Recombination-activating protein 1 zinc-finger domain zf-RING_2 PF13639.6 EWM25252.1 - 0.081 13.3 0.3 0.11 12.9 0.3 1.2 1 0 0 1 1 1 0 Ring finger domain Mu-like_Com PF10122.9 EWM25252.1 - 0.096 12.2 0.4 0.15 11.5 0.4 1.4 1 1 0 1 1 1 0 Mu-like prophage protein Com Tubulin_C PF03953.17 EWM25254.1 - 1.3e-14 54.4 0.1 1.5e-14 54.2 0.1 1.1 1 0 0 1 1 1 1 Tubulin C-terminal domain PH_RBD PF12068.8 EWM25254.1 - 0.057 12.9 0.0 0.057 12.9 0.0 1.1 1 0 0 1 1 1 0 Rab-binding domain (RBD) Ribosomal_L2_C PF03947.18 EWM25256.1 - 0.0081 16.4 3.6 0.0081 16.4 3.6 2.1 1 1 1 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EWM25257.1 - 3.5e-06 26.9 0.6 4.9e-06 26.4 0.1 1.6 1 1 1 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Med7 PF05983.11 EWM25259.1 - 0.00012 22.2 0.0 0.00015 22.0 0.0 1.3 1 1 0 1 1 1 1 MED7 protein COG7 PF10191.9 EWM25260.1 - 1.2e-10 40.3 0.0 1.4e-10 40.1 0.0 1.0 1 0 0 1 1 1 1 Golgi complex component 7 (COG7) YWFCY PF14293.6 EWM25263.1 - 0.21 12.0 0.3 0.33 11.3 0.3 1.3 1 0 0 1 1 1 0 YWFCY protein Vps4_C PF09336.10 EWM25264.1 - 1.1e-14 54.1 0.0 1.5e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain TF_Zn_Ribbon PF08271.12 EWM25264.1 - 0.18 11.4 3.8 0.16 11.5 1.5 2.1 3 0 0 3 3 3 0 TFIIB zinc-binding MIT PF04212.18 EWM25266.1 - 2.4e-13 49.9 0.1 3.7e-13 49.3 0.1 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 EWM25266.1 - 0.018 15.0 0.3 0.16 12.1 0.1 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EWM25266.1 - 0.11 12.7 0.3 0.38 11.0 0.3 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 EWM25266.1 - 0.11 12.3 1.4 0.3 11.0 0.7 2.1 2 1 0 2 2 2 0 Tetratricopeptide repeat VRR_NUC PF08774.11 EWM25267.1 - 1.7e-06 28.1 0.1 2.2e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 VRR-NUC domain 5-FTHF_cyc-lig PF01812.20 EWM25268.1 - 1e-37 129.8 0.0 1.4e-37 129.4 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family 5-FTHF_cyc-lig PF01812.20 EWM25269.1 - 1e-37 129.8 0.0 1.4e-37 129.4 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family FAM183 PF14886.6 EWM25270.1 - 0.42 11.4 4.2 3.2 8.5 4.2 2.1 1 1 0 1 1 1 0 FAM183A and FAM183B related DUF357 PF04010.13 EWM25271.1 - 0.099 12.7 0.3 0.59 10.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF357) zf-ZPR1 PF03367.13 EWM25273.1 - 0.0069 16.3 0.0 0.0085 16.0 0.0 1.2 1 0 0 1 1 1 1 ZPR1 zinc-finger domain zf-ZPR1 PF03367.13 EWM25274.1 - 4.7e-40 137.1 0.1 6.1e-40 136.7 0.1 1.1 1 0 0 1 1 1 1 ZPR1 zinc-finger domain LCM PF04072.14 EWM25275.1 - 1.6e-21 77.1 0.2 4.9e-21 75.5 0.2 1.6 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Glt_symporter PF03616.14 EWM25278.1 - 0.0045 15.7 0.0 0.0047 15.7 0.0 1.0 1 0 0 1 1 1 1 Sodium/glutamate symporter Thioredoxin PF00085.20 EWM25280.1 - 2.6e-09 37.0 0.0 3.7e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EWM25280.1 - 0.063 13.7 0.4 0.13 12.7 0.4 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain THOC2_N PF16134.5 EWM25283.1 - 7.4 5.1 9.4 10 4.6 9.4 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus DUF3336 PF11815.8 EWM25284.1 - 4.4e-36 123.6 0.4 6.2e-36 123.2 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EWM25284.1 - 1.4e-09 38.5 2.2 3.2e-09 37.3 2.2 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase TraT PF05818.12 EWM25284.1 - 0.069 12.8 0.2 0.11 12.2 0.2 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Glyco_hydro_127 PF07944.12 EWM25284.1 - 0.087 11.3 0.3 0.14 10.6 0.3 1.3 1 0 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 FKBP_C PF00254.28 EWM25288.1 - 2.6e-14 53.3 0.0 3.9e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase p450 PF00067.22 EWM25289.1 - 8.8e-71 239.0 0.0 1.1e-70 238.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TPR_20 PF14561.6 EWM25289.1 - 0.075 13.4 0.1 2.7 8.4 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF2162 PF09930.9 EWM25289.1 - 0.11 11.9 0.5 0.19 11.2 0.5 1.3 1 0 0 1 1 1 0 Predicted transporter (DUF2162) adh_short PF00106.25 EWM25290.1 - 3.4e-18 65.8 0.0 5.4e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EWM25290.1 - 1e-07 31.7 0.0 2.4e-07 30.5 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM25290.1 - 3.3e-05 23.9 0.0 6.5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 KR domain Pkinase PF00069.25 EWM25293.1 - 1.4e-73 247.5 0.0 1.7e-73 247.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM25293.1 - 7.2e-31 107.4 0.0 9.4e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EWM25293.1 - 1.7e-06 27.6 0.0 5.2e-06 26.0 0.0 1.8 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 EWM25293.1 - 1.7e-05 24.5 0.7 2.6e-05 23.9 0.1 1.6 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 EWM25293.1 - 0.0012 18.8 0.3 0.0012 18.8 0.3 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EWM25293.1 - 0.02 14.2 0.2 0.03 13.7 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EWM25293.1 - 0.13 11.0 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 EWM25293.1 - 0.16 11.0 0.0 0.49 9.3 0.0 1.7 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase SNF2_N PF00176.23 EWM25294.1 - 2.3e-51 174.6 0.0 2.8e-51 174.3 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EWM25294.1 - 2.5e-19 69.6 0.0 6.2e-19 68.4 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EWM25294.1 - 7.5e-06 26.1 0.0 2e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EWM25294.1 - 0.00021 21.1 0.0 0.00043 20.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 EWM25294.1 - 0.0003 20.1 0.0 0.00066 18.9 0.0 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 EWM25294.1 - 0.0061 16.3 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase TPT PF03151.16 EWM25295.1 - 2.7e-25 89.3 20.6 3.3e-25 89.0 20.6 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EWM25295.1 - 0.00012 22.3 37.3 0.00055 20.1 14.2 2.7 2 1 0 2 2 2 2 EamA-like transporter family COX14 PF14880.6 EWM25295.1 - 2.5 8.0 4.6 1.7 8.5 0.0 2.8 3 0 0 3 3 3 0 Cytochrome oxidase c assembly Peptidase_S24 PF00717.23 EWM25296.1 - 1.7e-13 50.3 0.2 7e-13 48.3 0.2 1.9 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 EWM25296.1 - 3.7e-13 49.5 0.0 6.2e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 DUF3449 PF11931.8 EWM25297.1 - 2.1e-74 249.3 2.0 3.7e-74 248.5 2.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) Telomere_Sde2_2 PF13297.6 EWM25297.1 - 1.6e-25 88.5 2.8 3.4e-25 87.5 2.8 1.6 1 0 0 1 1 1 1 Telomere stability C-terminal SF3A3 PF16837.5 EWM25297.1 - 3.8e-21 75.4 0.2 7.8e-21 74.4 0.2 1.5 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 EWM25297.1 - 3.2e-06 26.9 0.4 8.5e-06 25.5 0.4 1.8 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain Desulfoferrod_N PF06397.12 EWM25297.1 - 0.33 10.6 1.2 0.72 9.5 1.2 1.5 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain PRP9_N PF16958.5 EWM25297.1 - 1.9 8.5 6.8 0.95 9.5 0.0 2.9 2 1 1 3 3 3 0 Pre-mRNA-splicing factor PRP9 N-terminus CvfB_WH PF17783.1 EWM25298.1 - 0.088 12.6 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 CvfB-like winged helix domain DNA_ligase_A_N PF04675.14 EWM25299.1 - 8.7e-32 110.8 0.0 1.2e-31 110.4 0.0 1.2 1 0 0 1 1 1 1 DNA ligase N terminus BRCT_2 PF16589.5 EWM25301.1 - 1.4e-06 28.6 0.0 0.00034 21.0 0.0 3.0 2 1 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EWM25301.1 - 6.9e-05 23.1 0.4 0.14 12.6 0.0 4.2 4 1 0 4 4 4 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EWM25301.1 - 0.0039 17.1 0.0 0.088 12.8 0.0 2.4 2 0 0 2 2 2 1 twin BRCT domain GFO_IDH_MocA PF01408.22 EWM25302.1 - 9.1e-17 62.0 0.3 1.8e-16 61.0 0.1 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 EWM25302.1 - 0.021 15.1 0.1 0.23 11.7 0.1 2.1 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Arf PF00025.21 EWM25302.1 - 0.18 11.2 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family TFIIB PF00382.19 EWM25303.1 - 1.2e-25 89.3 8.5 1.4e-13 50.7 0.1 3.6 4 0 0 4 4 4 2 Transcription factor TFIIB repeat BRF1 PF07741.13 EWM25303.1 - 8.3e-14 51.8 2.1 8.3e-14 51.8 2.1 3.0 3 0 0 3 3 3 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 EWM25303.1 - 0.00027 20.4 1.8 0.00056 19.4 1.8 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding RskA PF10099.9 EWM25303.1 - 0.0011 19.3 8.8 0.14 12.4 1.5 2.5 2 0 0 2 2 2 2 Anti-sigma-K factor rskA HTH_Tnp_ISL3 PF13542.6 EWM25303.1 - 0.064 12.7 0.1 0.4 10.1 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Ribosomal_L18_c PF14204.6 EWM25303.1 - 0.57 11.2 8.5 0.35 11.8 4.3 2.4 2 0 0 2 2 2 0 Ribosomal L18 C-terminal region K_channel_TID PF07941.11 EWM25303.1 - 4.9 7.7 30.1 1.5 9.3 4.1 3.8 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain Sulfate_transp PF00916.20 EWM25304.1 - 1.4e-38 132.7 10.6 1.9e-38 132.2 10.6 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EWM25304.1 - 0.0022 17.6 0.0 0.0044 16.6 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EWM25304.1 - 0.018 15.5 4.6 0.018 15.5 4.6 4.1 4 1 0 4 4 4 0 Molybdate transporter of MFS superfamily Antifungal_prot PF11402.8 EWM25305.1 - 0.028 14.6 1.2 0.048 13.9 1.2 1.3 1 0 0 1 1 1 0 Antifungal protein N_Asn_amidohyd PF14736.6 EWM25306.1 - 8.9e-31 107.0 1.0 1.5e-19 70.2 0.1 3.2 3 1 0 3 3 3 2 Protein N-terminal asparagine amidohydrolase DUF4079 PF13301.6 EWM25307.1 - 4.2e-45 153.4 0.2 6.4e-45 152.8 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4079) TMF_TATA_bd PF12325.8 EWM25307.1 - 0.27 11.4 0.8 6.2 7.1 0.3 2.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding IF-2B PF01008.17 EWM25308.1 - 1.8e-59 201.3 0.0 3.4e-59 200.4 0.0 1.4 1 1 0 1 1 1 1 Initiation factor 2 subunit family STI1 PF17830.1 EWM25309.1 - 5.9e-05 22.9 6.0 9.5e-05 22.3 6.0 1.3 1 0 0 1 1 1 1 STI1 domain SAP PF02037.27 EWM25309.1 - 0.00085 19.0 0.4 0.0023 17.7 0.1 1.9 2 0 0 2 2 2 1 SAP domain GTP_EFTU PF00009.27 EWM25310.1 - 2.7e-49 167.4 0.8 4.5e-49 166.6 0.8 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 EWM25310.1 - 4.8e-41 139.2 3.9 1e-40 138.2 3.9 1.6 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 EWM25310.1 - 1.1e-15 57.4 0.0 3e-15 56.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 EWM25310.1 - 0.00062 19.8 0.0 0.0017 18.4 0.0 1.8 1 1 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.22 EWM25310.1 - 0.00083 19.0 0.1 0.0014 18.2 0.1 1.4 1 0 0 1 1 1 1 Ras family GTP_EFTU_D2 PF03144.25 EWM25310.1 - 0.0011 19.3 0.1 0.0027 18.1 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EWM25310.1 - 0.0045 16.8 0.0 0.0092 15.8 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain SRPRB PF09439.10 EWM25310.1 - 0.0078 15.7 0.0 0.033 13.6 0.0 2.0 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Helicase_C PF00271.31 EWM25311.1 - 3.5e-18 66.0 0.0 6.8e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EWM25311.1 - 4.8e-08 32.1 0.3 5.9e-08 31.8 0.3 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain AP2 PF00847.20 EWM25312.1 - 2.5e-13 50.0 9.1 5.8e-06 26.4 1.4 4.4 4 0 0 4 4 4 3 AP2 domain adh_short PF00106.25 EWM25314.1 - 3e-37 128.0 0.0 3.7e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EWM25314.1 - 2.4e-25 89.5 0.0 3.2e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM25314.1 - 1.2e-09 38.3 0.0 1.8e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EWM25314.1 - 1.8e-06 27.6 0.0 2.7e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 EWM25314.1 - 0.0016 18.4 0.0 0.0035 17.2 0.0 1.6 1 1 1 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EWM25314.1 - 0.012 15.1 0.0 0.27 10.7 0.0 2.5 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family PGM_PMM_I PF02878.16 EWM25315.1 - 1.4e-31 109.0 0.1 6.1e-31 107.0 0.1 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EWM25315.1 - 5.9e-27 94.1 0.0 1.4e-26 92.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EWM25315.1 - 9.4e-11 42.3 0.1 1.1e-09 38.8 0.2 2.7 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EWM25315.1 - 3.3e-05 24.0 0.0 8.4e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain U-box PF04564.15 EWM25316.1 - 1.5e-07 31.5 0.0 2.8e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 EWM25316.1 - 0.016 15.3 0.6 0.045 13.9 0.0 2.0 3 0 0 3 3 3 0 Zinc-finger of nitric oxide synthase-interacting protein T3SS_needle_F PF09392.10 EWM25317.1 - 0.0061 16.7 0.1 0.035 14.3 0.0 2.2 2 0 0 2 2 2 1 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF STI1 PF17830.1 EWM25318.1 - 2e-06 27.6 29.4 0.035 14.0 0.4 6.0 2 2 4 6 6 6 4 STI1 domain GerD PF17898.1 EWM25318.1 - 0.00014 21.8 26.1 0.018 15.0 6.7 3.5 2 2 1 3 3 3 2 Spore germination GerD central core domain SapB_1 PF05184.15 EWM25318.1 - 0.00022 21.1 0.1 1.1 9.4 0.0 3.0 2 1 0 2 2 2 2 Saposin-like type B, region 1 Ins_allergen_rp PF06757.13 EWM25318.1 - 0.0035 17.3 1.9 3.7 7.5 0.1 3.0 2 1 1 3 3 3 2 Insect allergen related repeat, nitrile-specifier detoxification DUF1641 PF07849.11 EWM25318.1 - 0.015 15.2 2.2 1.6 8.7 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1641) PDGLE PF13190.6 EWM25318.1 - 0.042 13.8 5.4 1.5 8.7 0.6 3.4 2 2 0 2 2 2 0 PDGLE domain Stealth_CR1 PF17101.5 EWM25318.1 - 0.25 11.1 0.1 30 4.4 0.0 2.8 2 0 0 2 2 2 0 Stealth protein CR1, conserved region 1 PSD4 PF07631.11 EWM25318.1 - 0.35 11.4 13.1 0.65 10.5 0.8 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1592) EcoR124_C PF12008.8 EWM25318.1 - 0.47 10.0 8.8 2 8.0 2.9 2.1 1 1 1 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal MMPL PF03176.15 EWM25318.1 - 0.66 8.9 10.5 0.81 8.6 5.7 2.3 1 1 1 2 2 2 0 MMPL family Not1 PF04054.15 EWM25318.1 - 0.71 8.7 4.5 0.47 9.3 0.3 2.2 1 1 0 2 2 2 0 CCR4-Not complex component, Not1 Imm51 PF15595.6 EWM25318.1 - 2.1 8.3 5.8 2.4 8.1 1.7 2.7 2 1 1 3 3 3 0 Immunity protein 51 FYVE PF01363.21 EWM25320.1 - 2.7e-15 56.2 7.4 5.1e-15 55.4 7.4 1.5 1 0 0 1 1 1 1 FYVE zinc finger PH_6 PF15406.6 EWM25320.1 - 0.0095 16.2 0.0 0.021 15.1 0.0 1.5 2 0 0 2 2 2 1 Pleckstrin homology domain DZR PF12773.7 EWM25320.1 - 0.33 11.0 5.3 8.6 6.5 5.3 2.4 1 1 0 1 1 1 0 Double zinc ribbon IBR PF01485.21 EWM25320.1 - 0.38 11.0 5.3 0.28 11.4 2.7 2.1 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Synaphin PF05835.12 EWM25320.1 - 0.52 10.6 5.3 0.77 10.0 5.3 1.2 1 0 0 1 1 1 0 Synaphin protein FYVE_2 PF02318.16 EWM25320.1 - 3 8.1 12.8 0.91 9.8 7.2 2.6 2 1 1 3 3 3 0 FYVE-type zinc finger Ras PF00071.22 EWM25322.1 - 5.6e-57 191.9 0.0 6.6e-57 191.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EWM25322.1 - 1.4e-33 115.7 0.0 2.4e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EWM25322.1 - 3.7e-14 52.6 0.0 4.7e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EWM25322.1 - 0.0015 18.6 0.0 0.003 17.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EWM25322.1 - 0.0054 16.3 0.0 0.015 14.9 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EWM25322.1 - 0.054 13.4 0.0 11 5.9 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Gtr1_RagA PF04670.12 EWM25322.1 - 0.062 12.6 0.0 0.074 12.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AIRC PF00731.20 EWM25322.1 - 0.083 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 AIR carboxylase DUF3040 PF11239.8 EWM25323.1 - 9.9 6.5 6.1 7.2 7.0 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3040) WD40 PF00400.32 EWM25324.1 - 5.9e-13 49.1 7.0 0.012 16.4 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM25324.1 - 2.8e-07 30.8 0.0 3.4 8.0 0.0 4.4 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EWM25324.1 - 6.3e-05 22.1 0.0 0.13 11.2 0.0 2.8 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EWM25324.1 - 0.015 15.3 3.1 8.1 6.5 0.0 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat eIF2A PF08662.11 EWM25324.1 - 0.036 14.0 0.0 0.74 9.7 0.0 2.7 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A HIRA_B PF09453.10 EWM25324.1 - 0.05 13.5 0.6 0.05 13.5 0.6 2.7 2 0 0 2 2 2 0 HIRA B motif Mito_carr PF00153.27 EWM25325.1 - 2.9e-32 110.5 0.2 2.9e-14 52.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyoxalase PF00903.25 EWM25331.1 - 1.8e-08 34.7 0.0 0.0012 19.0 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EWM25331.1 - 0.076 13.8 0.0 1.5 9.7 0.0 2.4 2 0 0 2 2 2 0 Glyoxalase-like domain TRAM_LAG1_CLN8 PF03798.16 EWM25332.1 - 1.1e-23 84.1 1.7 1.7e-23 83.4 1.7 1.3 1 0 0 1 1 1 1 TLC domain DUF4149 PF13664.6 EWM25332.1 - 0.55 10.6 10.5 0.7 10.2 1.5 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) Activator_LAG-3 PF11498.8 EWM25333.1 - 0.073 12.0 7.5 0.14 11.1 7.5 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Motilin_ghrelin PF04644.12 EWM25333.1 - 4.1 7.3 6.2 12 5.8 6.2 1.8 1 0 0 1 1 1 0 Motilin/ghrelin Band_7 PF01145.25 EWM25334.1 - 2.5e-26 92.8 0.1 3.3e-26 92.4 0.1 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family WD40 PF00400.32 EWM25335.1 - 3.2e-16 59.4 9.6 2.8e-06 28.0 0.3 6.1 7 0 0 7 7 7 4 WD domain, G-beta repeat E1_dh PF00676.20 EWM25336.1 - 3.5e-91 305.3 0.0 4.4e-91 304.9 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 EWM25336.1 - 0.00011 22.0 0.0 0.00033 20.5 0.0 1.7 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.21 EWM25336.1 - 0.00014 20.9 0.0 0.00025 20.1 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.6 EWM25336.1 - 0.0059 15.9 0.0 0.014 14.6 0.0 1.5 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase RRM_1 PF00076.22 EWM25337.1 - 0.024 14.5 0.0 0.3 10.9 0.0 2.4 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) La PF05383.17 EWM25337.1 - 0.086 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 La domain DUF4598 PF15370.6 EWM25339.1 - 0.12 12.8 1.4 0.22 12.0 1.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4598) ECH_1 PF00378.20 EWM25340.1 - 1.5e-79 266.9 2.4 1.7e-79 266.7 2.4 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EWM25340.1 - 4.2e-37 128.4 3.6 3.7e-35 122.0 2.6 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase DUF5612 PF18462.1 EWM25340.1 - 0.026 14.3 1.7 0.066 13.0 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5612) PAP_assoc PF03828.19 EWM25341.1 - 1.5e-14 53.9 0.0 3.6e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EWM25341.1 - 0.00015 21.9 0.0 0.0026 18.0 0.0 2.6 3 0 0 3 3 3 1 Nucleotidyltransferase domain DnaJ PF00226.31 EWM25343.1 - 3.9e-20 71.7 0.1 3.9e-20 71.7 0.1 2.2 3 0 0 3 3 3 1 DnaJ domain Death PF00531.22 EWM25343.1 - 0.092 12.9 0.9 0.3 11.3 0.1 2.1 2 0 0 2 2 2 0 Death domain GTP_EFTU PF00009.27 EWM25343.1 - 0.13 11.8 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Glu_syn_central PF04898.14 EWM25343.1 - 0.18 11.3 0.1 0.53 9.7 0.1 1.8 1 1 1 2 2 2 0 Glutamate synthase central domain PI3_PI4_kinase PF00454.27 EWM25344.1 - 5e-28 98.6 0.0 8.2e-20 71.7 0.0 2.5 2 1 1 3 3 3 2 Phosphatidylinositol 3- and 4-kinase FYVE PF01363.21 EWM25344.1 - 0.00063 19.8 4.8 0.0015 18.6 4.8 1.6 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 EWM25344.1 - 0.0047 17.4 0.0 0.011 16.2 0.0 1.5 1 0 0 1 1 1 1 PH domain DUF3727 PF12527.8 EWM25345.1 - 1.4e-06 28.5 2.9 0.12 12.6 0.1 2.9 2 1 1 3 3 3 2 Protein of unknown function (DUF3727) CPSF100_C PF13299.6 EWM25345.1 - 0.058 13.6 0.1 0.07 13.3 0.1 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Radial_spoke PF04712.12 EWM25345.1 - 0.082 11.8 2.1 0.1 11.5 2.1 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein DUF4637 PF15470.6 EWM25345.1 - 0.28 10.9 7.4 0.47 10.2 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) CDC45 PF02724.14 EWM25345.1 - 0.43 8.8 5.0 0.58 8.4 5.0 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 EWM25345.1 - 2.1 6.8 5.1 2.7 6.4 5.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NOA36 PF06524.12 EWM25345.1 - 3.2 7.0 8.4 4.5 6.5 8.4 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 EWM25345.1 - 4.2 5.4 13.0 5.3 5.0 13.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Ribosomal_L44 PF00935.19 EWM25346.1 - 7.7e-35 119.2 13.9 7.7e-35 119.2 13.9 1.4 1 1 0 1 1 1 1 Ribosomal protein L44 CDP-OH_P_transf PF01066.21 EWM25347.1 - 7.1e-17 61.9 0.2 7.1e-17 61.9 0.2 3.6 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase DOT1 PF08123.13 EWM25348.1 - 0.003 17.1 0.0 0.007 15.9 0.0 1.7 2 0 0 2 2 2 1 Histone methylation protein DOT1 zf-C2H2 PF00096.26 EWM25348.1 - 0.017 15.6 1.2 0.017 15.6 1.2 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type TPR_1 PF00515.28 EWM25349.1 - 2.5e-09 36.6 2.1 0.67 9.9 0.0 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 EWM25349.1 - 5.8e-09 35.4 8.8 11 6.4 0.0 9.9 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_19 PF14559.6 EWM25349.1 - 3.6e-07 30.6 24.6 0.0034 17.9 0.1 7.5 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 EWM25349.1 - 7.2e-06 25.6 0.0 1.9 8.2 0.0 4.4 4 0 0 4 4 4 2 TPR repeat TPR_8 PF13181.6 EWM25349.1 - 1.3e-05 25.0 0.1 2.6 8.5 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EWM25349.1 - 0.00037 20.3 3.1 4.5 7.5 0.0 5.7 7 0 0 7 7 7 2 Tetratricopeptide repeat NARP1 PF12569.8 EWM25349.1 - 0.00045 19.3 0.0 0.00085 18.4 0.0 1.4 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 ANAPC3 PF12895.7 EWM25349.1 - 0.0028 17.8 1.7 24 5.2 0.0 5.6 6 1 0 6 6 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EWM25349.1 - 0.0057 17.0 0.0 3.5 8.2 0.0 4.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 EWM25349.1 - 0.072 13.2 13.0 2.5 8.3 0.3 5.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EWM25349.1 - 0.82 10.4 8.6 1.9e+02 3.0 0.1 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF1003 PF06210.11 EWM25351.1 - 7.8e-30 103.1 0.0 1.4e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1003) DUF89 PF01937.19 EWM25352.1 - 4.9e-85 285.6 0.0 6e-85 285.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Hydrolase_6 PF13344.6 EWM25353.1 - 8.7e-28 96.4 0.0 2e-27 95.3 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EWM25353.1 - 8.9e-17 60.9 0.0 1.6e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EWM25353.1 - 7.7e-10 39.4 0.0 1.7e-09 38.3 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EWM25353.1 - 1.2e-08 35.3 0.0 1.7e-05 25.0 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Lycopene_cycl PF05834.12 EWM25354.1 - 5.9e-85 285.6 0.0 9e-85 285.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NFACT-R_1 PF05670.13 EWM25354.1 - 8.6e-33 113.3 0.1 1.8e-32 112.2 0.1 1.5 1 0 0 1 1 1 1 NFACT protein RNA binding domain Trp_halogenase PF04820.14 EWM25354.1 - 3.4e-08 32.8 0.7 0.002 17.0 0.1 2.5 3 0 0 3 3 3 2 Tryptophan halogenase Pyr_redox_2 PF07992.14 EWM25354.1 - 0.00011 21.5 0.0 0.00025 20.4 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EWM25354.1 - 0.00035 19.9 4.7 0.0037 16.6 0.2 2.6 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 EWM25354.1 - 0.00078 18.8 0.0 0.0015 17.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 EWM25354.1 - 0.0013 18.9 0.0 0.0039 17.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EWM25354.1 - 0.0028 16.4 2.9 0.0041 15.9 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 EWM25354.1 - 0.016 14.5 0.2 0.016 14.5 0.2 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EWM25354.1 - 0.043 13.8 0.0 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 EWM25354.1 - 0.058 12.5 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A DAO PF01266.24 EWM25354.1 - 0.066 12.8 0.4 0.66 9.5 0.1 2.1 1 1 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EWM25354.1 - 0.11 11.6 0.1 0.21 10.6 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain PVL_ORF50 PF07768.11 EWM25354.1 - 0.14 12.4 7.3 0.35 11.2 7.3 1.6 1 0 0 1 1 1 0 PVL ORF-50-like family Sacchrp_dh_NADP PF03435.18 EWM25354.1 - 0.17 12.1 0.2 0.54 10.5 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DUF3391 PF11871.8 EWM25354.1 - 0.21 12.1 3.8 0.41 11.2 3.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) 3HCDH_N PF02737.18 EWM25354.1 - 0.49 10.3 0.0 0.49 10.3 0.0 1.7 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3824 PF12868.7 EWM25354.1 - 1.1 9.9 6.3 3.1 8.4 6.3 1.7 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Mito_carr PF00153.27 EWM25355.1 - 4.5e-52 174.0 1.8 2.6e-16 59.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 EWM25356.1 - 5.9e-16 58.8 3.5 1.1e-15 58.0 3.5 1.5 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.9 EWM25356.1 - 0.11 12.7 3.9 1 9.5 0.2 2.6 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide PARP PF00644.20 EWM25357.1 - 1.1e-06 28.4 0.2 2e-06 27.6 0.2 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain ARTD15_N PF18084.1 EWM25357.1 - 0.0023 18.1 0.0 0.0048 17.1 0.0 1.5 1 0 0 1 1 1 1 ARTD15 N-terminal domain Apt1 PF10351.9 EWM25357.1 - 0.59 8.9 4.0 0.8 8.5 4.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 EWM25357.1 - 4.4 7.1 9.2 7.6 6.3 9.2 1.3 1 0 0 1 1 1 0 SPX domain Chloroa_b-bind PF00504.21 EWM25359.1 - 1.3e-37 129.8 0.1 2.8e-37 128.7 0.1 1.5 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DUF4813 PF16072.5 EWM25359.1 - 0.039 13.6 22.3 0.058 13.0 22.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Totivirus_coat PF05518.11 EWM25359.1 - 1.2 7.0 10.2 1.6 6.7 10.2 1.1 1 0 0 1 1 1 0 Totivirus coat protein peroxidase PF00141.23 EWM25361.1 - 3.4e-43 148.0 0.0 4.5e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 Peroxidase Complex1_LYR PF05347.15 EWM25362.1 - 3.5e-09 36.6 0.3 5.8e-09 35.9 0.3 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DHHA2 PF02833.14 EWM25363.1 - 4.1e-20 72.4 0.0 7.1e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 EWM25363.1 - 9.1e-08 32.3 0.0 2e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 DHH family DUF1424 PF07232.11 EWM25363.1 - 0.19 10.7 0.0 0.36 9.8 0.0 1.3 1 0 0 1 1 1 0 Putative rep protein (DUF1424) FAA_hydrolase PF01557.18 EWM25364.1 - 6.2e-55 186.2 0.0 8.7e-55 185.7 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 EWM25364.1 - 2.9e-29 101.4 0.0 5.3e-29 100.5 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal GST_N PF02798.20 EWM25364.1 - 5.3e-16 58.7 0.0 9.9e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EWM25364.1 - 6.9e-16 58.4 0.0 1.5e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EWM25364.1 - 3.4e-13 49.7 0.0 6.7e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EWM25364.1 - 0.00032 20.8 0.0 0.00062 19.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EWM25364.1 - 0.0015 18.5 0.0 0.0052 16.8 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EWM25364.1 - 0.0016 18.6 0.0 0.0036 17.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain IGPS PF00218.21 EWM25366.1 - 1e-29 103.5 0.0 1.4e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase ThiG PF05690.14 EWM25366.1 - 7.6e-06 25.4 4.7 0.0069 15.7 0.5 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 EWM25366.1 - 0.01 14.9 3.3 0.023 13.7 0.3 2.3 1 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain ADH_zinc_N PF00107.26 EWM25366.1 - 0.012 15.5 0.2 0.043 13.8 0.1 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase HeH PF12949.7 EWM25367.1 - 1.3e-06 27.9 1.6 4e-06 26.4 1.6 1.8 1 0 0 1 1 1 1 HeH/LEM domain Mito_carr PF00153.27 EWM25368.1 - 1.2e-48 163.0 5.2 3.3e-15 55.8 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.25 EWM25369.1 - 3.4e-60 203.6 0.0 4.3e-60 203.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM25369.1 - 7.3e-23 81.2 0.1 1.8e-22 79.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EWM25369.1 - 5e-06 26.0 0.5 0.002 17.5 0.0 2.5 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 EWM25369.1 - 0.00046 20.2 0.8 0.011 15.7 0.3 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EWM25369.1 - 0.00071 19.0 0.1 0.0014 18.0 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EWM25369.1 - 0.022 14.4 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.11 EWM25369.1 - 0.26 10.1 0.4 0.42 9.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) SnoaL_2 PF12680.7 EWM25371.1 - 0.11 13.2 0.0 0.27 11.9 0.0 1.8 1 1 0 1 1 1 0 SnoaL-like domain SnoaL_4 PF13577.6 EWM25371.1 - 0.13 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain Ank_5 PF13857.6 EWM25372.1 - 1.1e-12 47.9 0.2 2.2e-07 31.0 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EWM25372.1 - 2e-10 41.1 0.1 3.5e-10 40.3 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EWM25372.1 - 1.2e-08 35.3 0.1 2.6e-05 24.7 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EWM25372.1 - 6.8e-06 26.0 0.1 0.65 10.7 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EWM25372.1 - 0.017 15.6 0.1 0.26 11.8 0.1 2.7 2 0 0 2 2 2 0 Ankyrin repeat DUF1356 PF07092.12 EWM25374.1 - 0.067 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) MPC PF03650.13 EWM25375.1 - 3e-35 120.7 1.2 4.1e-35 120.2 1.2 1.2 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Ank_2 PF12796.7 EWM25376.1 - 3.4e-70 232.6 3.8 6.4e-12 45.9 0.0 6.9 6 0 0 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EWM25376.1 - 3.2e-51 171.1 9.3 4.4e-06 27.1 0.1 10.5 7 3 3 10 10 10 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 EWM25376.1 - 8.9e-34 115.1 18.5 2.2e-05 24.6 0.0 10.8 6 3 6 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EWM25376.1 - 1.1e-30 102.3 13.2 0.00016 21.8 0.0 14.4 14 0 0 14 14 14 6 Ankyrin repeat Ank PF00023.30 EWM25376.1 - 5.6e-27 93.0 14.0 0.00017 21.9 0.0 12.7 13 1 0 13 13 13 5 Ankyrin repeat cNMP_binding PF00027.29 EWM25376.1 - 6.5e-17 61.4 0.1 9.9e-09 35.2 0.1 2.8 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ank_2 PF12796.7 EWM25377.1 - 4.1e-28 97.8 0.0 6.5e-08 33.1 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EWM25377.1 - 1e-21 77.0 0.4 1.7e-06 28.5 0.0 4.3 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EWM25377.1 - 3.2e-19 68.4 0.0 0.0028 18.0 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EWM25377.1 - 3.8e-19 68.5 0.1 1.6e-05 25.1 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EWM25377.1 - 8.9e-19 65.6 0.1 0.0006 20.1 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat BT1 PF03092.16 EWM25378.1 - 1.1e-96 324.2 12.7 1.1e-50 172.3 3.3 2.9 1 1 1 2 2 2 2 BT1 family MFS_1 PF07690.16 EWM25378.1 - 3.7e-14 52.4 43.8 1.4e-10 40.7 30.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Transgly PF00912.22 EWM25378.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Transglycosylase MFS_1_like PF12832.7 EWM25378.1 - 0.3 9.9 13.4 0.81 8.5 12.7 2.0 1 1 0 1 1 1 0 MFS_1 like family DUF1674 PF07896.12 EWM25379.1 - 6.3e-09 36.2 5.8 6.3e-09 36.2 5.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1674) Pro_isomerase PF00160.21 EWM25380.1 - 5.8e-11 42.9 0.0 1e-10 42.1 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF155 PF02582.14 EWM25381.1 - 1.5e-47 162.0 0.0 2.4e-47 161.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 GRP PF07172.11 EWM25381.1 - 0.0079 16.9 3.3 0.0079 16.9 3.3 2.1 2 0 0 2 2 2 1 Glycine rich protein family ABC_tran PF00005.27 EWM25382.1 - 1.4e-47 161.6 0.0 4e-23 82.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 EWM25382.1 - 9.2e-29 100.4 23.1 9.2e-29 100.4 23.1 2.4 3 0 0 3 3 3 1 ABC-2 type transporter AAA_21 PF13304.6 EWM25382.1 - 1.7e-16 60.9 0.4 0.0084 16.0 0.0 4.3 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EWM25382.1 - 6.3e-11 41.9 0.8 6e-05 22.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EWM25382.1 - 5.9e-10 39.3 0.2 0.00038 20.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EWM25382.1 - 7.7e-09 36.1 0.0 0.0025 18.2 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 EWM25382.1 - 2.2e-06 27.3 0.0 0.00013 21.4 0.0 2.9 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 EWM25382.1 - 2.4e-06 27.2 0.1 0.061 12.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EWM25382.1 - 1.4e-05 25.4 0.1 0.19 12.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EWM25382.1 - 2e-05 24.9 0.0 0.067 13.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 EWM25382.1 - 5.9e-05 23.4 0.5 0.18 12.0 0.3 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EWM25382.1 - 7e-05 23.4 0.0 0.086 13.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EWM25382.1 - 0.00016 21.9 0.0 0.57 10.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 EWM25382.1 - 0.0002 21.9 0.9 0.12 12.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EWM25382.1 - 0.00036 20.6 0.2 0.54 10.4 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_30 PF13604.6 EWM25382.1 - 0.0016 18.2 0.7 0.79 9.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EWM25382.1 - 0.0034 17.3 0.5 0.87 9.5 0.0 2.7 2 0 0 2 2 2 1 NACHT domain NTPase_1 PF03266.15 EWM25382.1 - 0.0045 16.9 1.0 7.3 6.5 0.0 3.9 4 0 0 4 4 4 0 NTPase SbcCD_C PF13558.6 EWM25382.1 - 0.0083 16.3 0.0 3.5 7.9 0.0 2.6 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ATPase_2 PF01637.18 EWM25382.1 - 0.02 14.8 0.0 0.066 13.1 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Dynamin_N PF00350.23 EWM25382.1 - 0.022 14.8 0.3 2.9 7.9 0.0 2.8 2 0 0 2 2 2 0 Dynamin family AAA_24 PF13479.6 EWM25382.1 - 0.027 14.2 0.9 8.1 6.1 0.1 2.7 3 0 0 3 3 3 0 AAA domain Cytidylate_kin PF02224.18 EWM25382.1 - 0.045 13.5 0.4 2.4 7.8 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase Rad17 PF03215.15 EWM25382.1 - 0.046 13.6 0.0 1.8 8.4 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain IstB_IS21 PF01695.17 EWM25382.1 - 0.061 13.0 0.1 8.5 6.1 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 EWM25382.1 - 0.063 12.6 1.6 6.6 5.9 0.2 2.3 2 0 0 2 2 2 0 Zeta toxin Toxin_14 PF07829.11 EWM25382.1 - 0.087 12.8 0.2 0.2 11.6 0.2 1.5 1 0 0 1 1 1 0 Alpha-A conotoxin PIVA-like protein T2SSE PF00437.20 EWM25382.1 - 0.088 11.9 0.0 3.1 6.8 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_ATPase PF09818.9 EWM25382.1 - 0.09 11.6 1.0 1.5 7.5 0.0 2.5 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_5 PF07728.14 EWM25382.1 - 0.13 12.2 0.8 11 6.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) cobW PF02492.19 EWM25382.1 - 0.18 11.4 1.1 8.4 5.9 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 EWM25382.1 - 0.19 12.1 0.3 5.3 7.5 0.0 3.1 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 EWM25382.1 - 0.28 11.6 1.4 25 5.3 0.1 2.5 2 0 0 2 2 2 0 AAA domain PSII_Pbs27 PF13326.6 EWM25384.1 - 3.4e-28 98.7 0.0 4e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Photosystem II Pbs27 GTP-bdg_M PF16360.5 EWM25385.1 - 4.3e-20 72.1 10.4 9.1e-20 71.1 10.4 1.6 1 0 0 1 1 1 1 GTP-binding GTPase Middle Region GTP-bdg_N PF13167.6 EWM25385.1 - 2e-18 66.9 0.1 8.3e-18 64.8 0.0 2.1 2 0 0 2 2 2 1 GTP-binding GTPase N-terminal MMR_HSR1 PF01926.23 EWM25385.1 - 1.3e-17 63.9 0.0 3.4e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EWM25385.1 - 3.8e-08 33.4 0.1 0.00023 21.1 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EWM25385.1 - 0.00074 19.1 0.2 0.0065 16.0 0.2 2.3 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 EWM25385.1 - 0.0018 18.2 0.0 0.0038 17.2 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain AAA_16 PF13191.6 EWM25385.1 - 0.0052 17.2 0.2 0.01 16.2 0.2 1.5 1 0 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.23 EWM25385.1 - 0.056 13.5 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Dynamin family cobW PF02492.19 EWM25385.1 - 0.066 12.8 0.4 0.56 9.8 0.0 2.2 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ras PF00071.22 EWM25385.1 - 0.12 11.9 0.1 4.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Ras family Fumble PF03630.14 EWM25386.1 - 3.8e-117 391.2 2.1 1.1e-86 291.0 0.2 2.7 2 1 0 2 2 2 2 Fumble MIP PF00230.20 EWM25387.1 - 1.7e-15 57.4 25.5 3.7e-09 36.6 0.3 4.2 2 2 1 3 3 3 3 Major intrinsic protein ENOD40 PF08247.11 EWM25387.1 - 0.098 12.7 1.1 0.21 11.6 1.1 1.6 1 0 0 1 1 1 0 ENOD40 protein UMPH-1 PF05822.12 EWM25388.1 - 2.4e-66 223.8 0.0 9.8e-36 123.5 0.0 2.1 2 0 0 2 2 2 2 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 EWM25388.1 - 0.016 15.6 2.0 0.36 11.2 1.1 2.5 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Glu_synthase PF01645.17 EWM25390.1 - 8.7e-156 518.7 0.4 1.6e-153 511.2 0.0 2.4 3 0 0 3 3 3 2 Conserved region in glutamate synthase GATase_2 PF00310.21 EWM25390.1 - 2.7e-152 507.3 0.0 5e-152 506.5 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.14 EWM25390.1 - 3.8e-103 344.8 0.0 2.3e-102 342.3 0.0 2.0 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 EWM25390.1 - 3.3e-71 238.8 7.3 5.3e-71 238.2 7.3 1.3 1 0 0 1 1 1 1 GXGXG motif FMN_dh PF01070.18 EWM25390.1 - 0.051 12.6 3.1 0.1 11.6 3.1 1.4 1 0 0 1 1 1 0 FMN-dependent dehydrogenase PfkB PF00294.24 EWM25391.1 - 3.3e-60 203.9 0.2 3.8e-60 203.8 0.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EWM25391.1 - 4.6e-13 49.1 0.0 8.2e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase GSHPx PF00255.19 EWM25392.1 - 3e-28 97.5 0.0 4.5e-28 97.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 EWM25392.1 - 0.0012 18.7 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EWM25392.1 - 0.0025 17.5 0.0 0.006 16.3 0.0 1.7 1 1 0 1 1 1 1 Redoxin Methyltransf_11 PF08241.12 EWM25393.1 - 4e-21 75.5 0.0 6.7e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM25393.1 - 4.9e-19 68.8 0.0 8e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM25393.1 - 2.9e-15 56.4 0.0 4.2e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EWM25393.1 - 8.3e-14 51.5 0.0 1.1e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EWM25393.1 - 3e-12 46.7 0.0 4.3e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EWM25393.1 - 5.3e-10 39.9 0.0 8e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EWM25393.1 - 3.1e-06 26.7 0.0 4.7e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 EWM25393.1 - 0.0036 17.4 0.0 0.017 15.2 0.0 2.0 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_29 PF03141.16 EWM25393.1 - 0.02 13.5 0.0 0.025 13.2 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_32 PF13679.6 EWM25393.1 - 0.02 14.9 0.0 0.03 14.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 EWM25393.1 - 0.029 13.9 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.14 EWM25393.1 - 0.037 13.6 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_9 PF08003.11 EWM25393.1 - 0.1 11.5 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_2 PF00891.18 EWM25393.1 - 0.12 11.7 0.1 0.29 10.4 0.1 1.6 1 1 0 1 1 1 0 O-methyltransferase domain adh_short PF00106.25 EWM25394.1 - 1.7e-41 141.9 0.0 2.2e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EWM25394.1 - 3.1e-23 82.6 0.0 4.2e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM25394.1 - 4.7e-07 29.9 0.0 7.2e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EWM25394.1 - 0.12 11.5 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GCK PF07802.11 EWM25395.1 - 2.3e-07 31.2 3.0 4.1e-07 30.3 3.0 1.5 1 0 0 1 1 1 1 GCK domain C8 PF08742.11 EWM25395.1 - 1.9 9.0 6.6 0.21 12.0 1.8 1.9 2 0 0 2 2 2 0 C8 domain DUF2993 PF11209.8 EWM25396.1 - 0.00016 22.0 1.4 0.00042 20.6 1.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2993) Ribosomal_S6 PF01250.17 EWM25397.1 - 2.5e-16 59.7 0.0 4.5e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6 DUF3084 PF11283.8 EWM25397.1 - 0.073 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3084) CBFD_NFYB_HMF PF00808.23 EWM25398.1 - 1.1e-16 60.9 0.2 2e-16 60.0 0.2 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EWM25398.1 - 7.7e-10 39.2 0.2 7.7e-10 39.2 0.2 3.1 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 Cytochrom_B558a PF05038.13 EWM25398.1 - 5.4 6.5 4.9 9.4 5.8 4.9 1.3 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit EMG1 PF03587.14 EWM25399.1 - 4.3e-65 219.0 0.0 5.1e-65 218.8 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase FAD_binding_8 PF08022.12 EWM25399.1 - 0.053 13.6 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 FAD-binding domain Peptidase_C1 PF00112.23 EWM25400.1 - 8.6e-42 143.7 3.7 1.3e-41 143.1 3.7 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EWM25400.1 - 0.025 13.4 1.3 0.19 10.5 0.6 2.0 2 0 0 2 2 2 0 Peptidase C1-like family UPF0370 PF13980.6 EWM25401.1 - 0.2 11.7 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) PCI PF01399.27 EWM25402.1 - 2.2e-10 41.0 0.0 7.7e-10 39.2 0.0 2.0 2 0 0 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 EWM25402.1 - 1 9.1 9.6 0.05 13.3 3.8 1.9 2 0 0 2 2 2 0 eIF3 subunit M, C-terminal helix Skp1 PF01466.19 EWM25403.1 - 3.3e-28 97.5 0.4 6.1e-28 96.7 0.4 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 EWM25403.1 - 2e-18 66.3 1.8 3.5e-18 65.5 1.8 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.31 EWM25403.1 - 0.086 13.1 0.2 0.85 9.9 0.2 2.2 1 1 0 1 1 1 0 BTB/POZ domain SnoaL_3 PF13474.6 EWM25404.1 - 1.4e-21 77.0 0.1 2.6e-21 76.1 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 EWM25404.1 - 3.2e-07 30.7 0.2 1.2e-06 28.8 0.1 2.0 2 1 1 3 3 3 1 Domain of unknown function (DUF4440) CaMKII_AD PF08332.10 EWM25404.1 - 5.9e-06 26.4 0.0 1.1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain SnoaL_2 PF12680.7 EWM25404.1 - 0.0003 21.4 0.2 0.00081 20.0 0.2 1.7 2 0 0 2 2 2 1 SnoaL-like domain SnoaL_4 PF13577.6 EWM25404.1 - 0.0004 20.5 0.1 0.00074 19.6 0.1 1.4 1 0 0 1 1 1 1 SnoaL-like domain DUF1539 PF07560.11 EWM25404.1 - 0.0016 18.5 0.3 0.004 17.2 0.0 1.7 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1539) CAF1A PF12253.8 EWM25404.1 - 0.0045 17.1 0.3 0.011 15.9 0.3 1.6 1 0 0 1 1 1 1 Chromatin assembly factor 1 subunit A DUF4632 PF15451.6 EWM25404.1 - 1.8 8.7 7.6 0.77 9.9 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4632) Peptidase_M3 PF01432.20 EWM25405.1 - 9.9e-117 391.0 0.0 1.3e-116 390.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 DUF4259 PF14078.6 EWM25405.1 - 0.039 14.7 0.6 0.11 13.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4259) gag_pre-integrs PF13976.6 EWM25405.1 - 0.078 12.9 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 GAG-pre-integrase domain Peptidase_M50B PF13398.6 EWM25405.1 - 0.12 12.0 0.4 0.19 11.3 0.4 1.2 1 0 0 1 1 1 0 Peptidase M50B-like TP6A_N PF04406.14 EWM25406.1 - 8.1e-22 77.0 0.2 1.8e-21 75.9 0.2 1.6 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2457 PF10446.9 EWM25406.1 - 0.75 8.9 25.2 0.33 10.1 5.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) BSP_II PF05432.11 EWM25406.1 - 2.3 7.9 31.1 1.9 8.1 10.2 2.1 1 1 0 2 2 2 0 Bone sialoprotein II (BSP-II) PBP1_TM PF14812.6 EWM25406.1 - 3.7 8.0 21.9 6.8 7.1 11.3 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_C1 PF00112.23 EWM25407.1 - 2e-56 191.5 0.0 3e-56 191.0 0.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EWM25407.1 - 9.8e-11 41.9 0.1 1.8e-10 41.1 0.1 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EWM25407.1 - 1.6e-06 27.2 0.3 0.00028 19.8 0.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family UL73_N PF12522.8 EWM25407.1 - 0.27 11.0 1.6 0.53 10.1 1.6 1.5 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal Peptidase_S10 PF00450.22 EWM25409.1 - 1e-106 357.9 0.0 1.2e-106 357.7 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase GST_N_3 PF13417.6 EWM25410.1 - 8.1e-09 35.8 0.1 1.7e-08 34.7 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 EWM25410.1 - 5.9e-08 32.8 0.7 1.3e-07 31.7 0.7 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.6 EWM25410.1 - 0.00057 19.9 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EWM25410.1 - 0.0015 19.2 0.0 0.0037 18.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_N_2 PF13409.6 EWM25410.1 - 0.006 16.9 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EWM25410.1 - 0.14 12.3 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain UCR_Fe-S_N PF10399.9 EWM25410.1 - 2.1 7.7 8.1 0.3 10.5 1.1 2.9 3 0 0 3 3 3 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal PIG-L PF02585.17 EWM25411.1 - 6.8e-24 85.0 0.0 1.4e-23 83.9 0.0 1.5 2 0 0 2 2 2 1 GlcNAc-PI de-N-acetylase Methyltransf_25 PF13649.6 EWM25412.1 - 8.2e-13 48.9 0.0 2.4e-12 47.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM25412.1 - 3.5e-11 43.1 0.6 1.7e-10 40.9 0.5 2.0 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EWM25412.1 - 1.2e-10 41.3 0.1 1.7e-10 40.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EWM25412.1 - 1.3e-09 38.6 0.1 4e-09 37.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 EWM25412.1 - 3.4e-08 32.8 0.0 4.6e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 EWM25412.1 - 5.4e-07 29.2 0.0 7.2e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EWM25412.1 - 1.6e-06 28.0 0.0 3.1e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EWM25412.1 - 1.5e-05 25.0 0.1 2.6e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EWM25412.1 - 6e-05 22.7 0.1 9.9e-05 21.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EWM25412.1 - 7.4e-05 23.4 0.0 0.00015 22.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EWM25412.1 - 0.00078 18.8 0.0 0.0014 17.9 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain FtsJ PF01728.19 EWM25412.1 - 0.0012 19.0 0.2 0.0022 18.1 0.2 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 EWM25412.1 - 0.0038 17.0 0.1 0.0063 16.3 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 EWM25412.1 - 0.0038 16.6 0.0 0.0062 15.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 EWM25412.1 - 0.0056 16.4 0.1 0.0096 15.7 0.1 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_32 PF13679.6 EWM25412.1 - 0.0076 16.3 0.0 0.014 15.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 EWM25412.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_24 PF13578.6 EWM25412.1 - 0.1 13.6 0.0 0.3 12.1 0.0 1.9 2 0 0 2 2 1 0 Methyltransferase domain TehB PF03848.14 EWM25412.1 - 0.14 11.5 0.1 0.31 10.4 0.1 1.7 1 1 0 1 1 1 0 Tellurite resistance protein TehB Pro_isomerase PF00160.21 EWM25413.1 - 2e-45 154.9 0.0 2.5e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thr_synth_N PF14821.6 EWM25414.1 - 4.6e-26 90.8 0.0 1.1e-25 89.6 0.0 1.7 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 EWM25414.1 - 6.3e-18 65.2 0.0 3.4e-17 62.8 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TMEM247 PF15444.6 EWM25415.1 - 0.023 14.8 0.4 0.023 14.8 0.4 1.1 1 0 0 1 1 1 0 Transmembrane protein 247 PHD PF00628.29 EWM25416.1 - 5.7e-25 87.0 36.4 2.5e-10 40.1 5.2 3.3 3 0 0 3 3 3 3 PHD-finger PHD_2 PF13831.6 EWM25416.1 - 2.6e-10 39.7 20.0 0.00015 21.2 2.4 3.7 3 0 0 3 3 3 3 PHD-finger 2OG-FeII_Oxy_3 PF13640.6 EWM25416.1 - 1.2e-08 35.7 0.0 2.3e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-PHD-like PF15446.6 EWM25416.1 - 0.008 15.8 27.5 0.075 12.7 4.0 3.6 3 1 0 3 3 3 3 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.6 EWM25416.1 - 0.14 12.1 25.6 1.4 8.9 2.4 3.9 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 DZR PF12773.7 EWM25416.1 - 9 6.4 34.5 2.1 8.5 10.7 4.1 2 1 2 4 4 4 0 Double zinc ribbon RRM_1 PF00076.22 EWM25417.1 - 1e-07 31.6 0.0 2e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1922 PF09082.10 EWM25417.1 - 0.15 12.4 0.9 16 5.8 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1922) EMP70 PF02990.16 EWM25418.1 - 1.3e-133 446.5 15.7 1.8e-133 446.0 15.7 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 DUF5438 PF17506.2 EWM25418.1 - 0.21 11.9 4.4 0.89 9.9 0.3 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5438) FancD2 PF14631.6 EWM25419.1 - 0.0017 15.9 0.3 0.0017 15.9 0.3 1.5 2 0 0 2 2 2 1 Fanconi anaemia protein FancD2 nuclease Mito_carr PF00153.27 EWM25420.1 - 1.7e-42 143.3 0.5 8.6e-19 67.3 0.0 4.3 2 2 1 3 3 3 3 Mitochondrial carrier protein TAT_signal PF10518.9 EWM25420.1 - 0.083 12.8 0.0 0.083 12.8 0.0 3.1 3 0 0 3 3 3 0 TAT (twin-arginine translocation) pathway signal sequence PsbP PF01789.16 EWM25422.1 - 1.2e-13 51.5 0.0 1.6e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 PsbP Codanin-1_C PF15296.6 EWM25423.1 - 0.069 13.2 2.0 0.13 12.3 2.0 1.6 1 1 0 1 1 1 0 Codanin-1 C-terminus Pex2_Pex12 PF04757.14 EWM25424.1 - 1.4e-31 109.8 0.0 1.9e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 EWM25424.1 - 2.6e-05 24.0 9.8 4.1e-05 23.3 9.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EWM25424.1 - 2.9e-05 23.9 6.2 4.6e-05 23.2 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EWM25424.1 - 4.6e-05 23.3 9.8 7.1e-05 22.7 9.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EWM25424.1 - 7.5e-05 22.5 9.7 0.00012 21.9 9.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EWM25424.1 - 7.7e-05 22.5 6.7 0.00013 21.8 6.7 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EWM25424.1 - 0.00028 21.1 9.0 0.00045 20.5 9.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EWM25424.1 - 0.00035 20.5 7.5 0.00063 19.7 7.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EWM25424.1 - 0.011 15.9 12.0 0.025 14.8 12.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 EWM25424.1 - 0.12 12.7 4.0 0.19 12.0 4.0 1.3 1 0 0 1 1 1 0 RING-H2 zinc finger domain Mu-like_Com PF10122.9 EWM25424.1 - 7.1 6.2 5.7 2.5 7.6 2.3 1.9 2 0 0 2 2 2 0 Mu-like prophage protein Com DUF1857 PF08982.11 EWM25425.1 - 0.044 13.6 0.0 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1857) Tcp11 PF05794.13 EWM25426.1 - 3.9e-53 181.1 0.2 5.6e-53 180.6 0.2 1.3 1 0 0 1 1 1 1 T-complex protein 11 DEAD PF00270.29 EWM25427.1 - 5.2e-18 65.4 0.0 8e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EWM25427.1 - 4.7e-15 55.9 0.0 4.5e-14 52.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EWM25427.1 - 0.0037 17.3 0.0 0.0066 16.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EWM25427.1 - 0.17 12.1 0.1 1.1 9.5 0.1 2.3 1 1 0 1 1 1 0 AAA domain Hydrolase PF00702.26 EWM25428.1 - 7e-17 62.4 0.0 6.3e-08 33.2 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EWM25428.1 - 2.4e-13 50.0 0.0 4.7e-11 42.5 0.0 3.1 3 1 0 3 3 3 2 E1-E2 ATPase Cation_ATPase PF13246.6 EWM25428.1 - 0.0017 18.4 0.0 0.004 17.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EWM25428.1 - 0.31 10.7 0.0 0.64 9.7 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase p450 PF00067.22 EWM25429.1 - 7.1e-78 262.4 0.0 1e-77 261.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 EWM25429.1 - 9.1e-40 136.6 0.0 1.6e-39 135.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EWM25429.1 - 9.3e-19 68.1 0.0 1.9e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EWM25429.1 - 1.3e-18 67.6 0.0 3.1e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 EWM25429.1 - 0.018 15.3 0.0 0.038 14.2 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain DUF4149 PF13664.6 EWM25431.1 - 1.6e-19 70.1 6.7 1.6e-19 70.1 6.7 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4149) DUF1772 PF08592.11 EWM25431.1 - 9.4e-05 22.8 5.0 0.0015 18.9 2.3 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1772) COesterase PF00135.28 EWM25433.1 - 5.4e-85 286.2 0.0 7.2e-85 285.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EWM25433.1 - 2e-07 31.1 0.1 1.2e-06 28.5 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Pkinase PF00069.25 EWM25434.1 - 2.3e-63 214.0 0.0 2.7e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM25434.1 - 4.2e-28 98.3 0.0 5.7e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EWM25434.1 - 0.0019 18.1 0.7 0.17 11.8 0.0 2.2 1 1 0 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EWM25434.1 - 0.023 13.7 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 EWM25434.1 - 0.044 13.1 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 EWM25434.1 - 0.071 12.4 0.0 0.13 11.5 0.0 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Chorismate_bind PF00425.18 EWM25435.1 - 7.9e-62 209.1 0.0 1.1e-61 208.7 0.0 1.1 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 EWM25435.1 - 9.8e-39 133.1 0.0 1.5e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EWM25435.1 - 1.7e-12 47.6 0.0 2.6e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase C26 Anth_synt_I_N PF04715.13 EWM25435.1 - 8.4e-12 45.5 0.0 6.5e-10 39.4 0.0 3.0 2 1 0 2 2 2 1 Anthranilate synthase component I, N terminal region Response_reg PF00072.24 EWM25435.1 - 0.0018 18.4 0.0 0.0035 17.5 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Gp45_2 PF17470.2 EWM25436.1 - 0.025 14.5 0.1 0.45 10.5 0.0 2.3 2 0 0 2 2 2 0 Phage gene product 45.2 VTC PF09359.10 EWM25437.1 - 3.2e-72 243.2 0.0 4.6e-72 242.7 0.0 1.2 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 EWM25437.1 - 5e-19 69.5 8.0 1.7e-09 38.1 0.3 3.8 3 1 1 4 4 4 3 SPX domain DUF202 PF02656.15 EWM25437.1 - 1.3e-11 44.8 0.2 2.4e-11 43.9 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) TauE PF01925.19 EWM25437.1 - 0.12 11.9 0.2 0.19 11.3 0.2 1.2 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE Ferritin PF00210.24 EWM25437.1 - 0.14 12.1 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 Ferritin-like domain Pkinase_Tyr PF07714.17 EWM25438.1 - 3.9e-56 190.2 0.0 5.1e-56 189.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EWM25438.1 - 1e-50 172.6 0.0 1.5e-50 172.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain EGF_2 PF07974.13 EWM25438.1 - 1.4e-14 54.2 95.3 1.7e-05 25.1 9.4 10.1 6 3 3 9 9 9 5 EGF-like domain Kinase-like PF14531.6 EWM25438.1 - 1.8e-06 27.5 0.0 2.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EWM25438.1 - 3.7e-05 23.2 0.6 0.0001 21.7 0.2 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EWM25438.1 - 7.4e-05 21.9 0.0 0.00012 21.2 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EWM25438.1 - 0.0011 19.0 0.1 0.0055 16.6 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EWM25438.1 - 0.0062 15.4 0.0 0.0093 14.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Laminin_EGF PF00053.24 EWM25438.1 - 0.0072 16.5 9.4 0.0072 16.5 9.4 6.8 5 1 1 6 6 6 3 Laminin EGF domain WD40 PF00400.32 EWM25440.1 - 1.2e-24 86.1 13.5 1.3e-05 25.9 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat Sof1 PF04158.14 EWM25440.1 - 2.4e-15 56.6 3.3 4.2e-15 55.8 3.3 1.4 1 0 0 1 1 1 1 Sof1-like domain ANAPC4_WD40 PF12894.7 EWM25440.1 - 3.3e-06 27.3 0.0 0.0056 16.9 0.0 4.1 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EWM25440.1 - 0.00018 21.5 0.0 0.028 14.3 0.0 2.6 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A ALMS_motif PF15309.6 EWM25440.1 - 0.0009 19.7 0.0 0.0016 18.9 0.0 1.3 1 0 0 1 1 1 1 ALMS motif CLP_protease PF00574.23 EWM25441.1 - 4.1e-77 258.2 0.8 5.4e-77 257.8 0.8 1.1 1 0 0 1 1 1 1 Clp protease Mito_carr PF00153.27 EWM25443.1 - 1.1e-66 220.8 1.2 3.1e-23 81.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein UPF0220 PF05255.11 EWM25443.1 - 0.091 12.3 0.2 0.22 11.1 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0220) SAYSvFN PF10260.9 EWM25444.1 - 5.7e-15 55.0 0.1 9.3e-15 54.3 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized conserved domain (SAYSvFN) CCD48 PF15799.5 EWM25444.1 - 0.87 7.8 4.2 1.1 7.5 4.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 Sporozoite_P67 PF05642.11 EWM25444.1 - 8.2 4.4 5.9 10 4.0 5.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen tRNA_U5-meth_tr PF05958.11 EWM25445.1 - 3.3e-21 75.7 0.0 2.9e-20 72.6 0.0 1.9 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 EWM25445.1 - 6.9e-05 22.7 0.3 0.00014 21.7 0.3 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM25445.1 - 0.00024 21.8 0.1 0.00058 20.5 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EWM25445.1 - 0.00088 18.7 0.0 0.0026 17.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 EWM25445.1 - 0.00098 18.7 0.1 0.0019 17.8 0.1 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.12 EWM25445.1 - 0.014 16.0 0.0 0.042 14.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EWM25445.1 - 0.05 13.1 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain TPMT PF05724.11 EWM25445.1 - 0.082 12.6 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_12 PF08242.12 EWM25445.1 - 0.2 12.4 0.0 6.2 7.6 0.1 2.3 2 0 0 2 2 2 0 Methyltransferase domain MFS_1 PF07690.16 EWM25447.1 - 3.3e-17 62.5 34.7 8.7e-17 61.1 28.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MerE PF05052.12 EWM25447.1 - 0.45 10.5 5.2 0.3 11.0 1.3 2.6 2 0 0 2 2 2 0 MerE protein DUF5600 PF18150.1 EWM25448.1 - 5e-27 94.6 0.1 1.3e-26 93.2 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) Dynamin_N PF00350.23 EWM25448.1 - 2.8e-13 50.3 0.0 2.7e-11 43.8 0.0 2.2 1 1 0 1 1 1 1 Dynamin family EHD_N PF16880.5 EWM25448.1 - 8.8e-13 47.9 0.3 1.5e-12 47.1 0.3 1.4 1 0 0 1 1 1 1 N-terminal EH-domain containing protein MMR_HSR1 PF01926.23 EWM25448.1 - 1.2e-08 35.0 0.0 2.9e-08 33.8 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EWM25448.1 - 0.00049 20.3 0.1 0.062 13.5 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 EWM25448.1 - 0.0035 16.9 0.0 0.11 12.0 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Ras PF00071.22 EWM25448.1 - 0.0064 16.1 0.1 0.75 9.4 0.0 2.2 2 0 0 2 2 2 1 Ras family Gtr1_RagA PF04670.12 EWM25448.1 - 0.018 14.4 0.2 0.098 12.0 0.2 1.9 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EWM25448.1 - 0.023 14.6 0.0 2.4 8.0 0.0 2.9 3 1 0 3 3 3 0 RsgA GTPase AAA_16 PF13191.6 EWM25448.1 - 0.15 12.4 0.1 0.98 9.8 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain G6PD_C PF02781.16 EWM25449.1 - 3.8e-38 131.3 0.0 1.1e-37 129.9 0.0 1.6 1 1 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain UPF0020 PF01170.18 EWM25450.1 - 0.0038 16.9 0.1 0.0062 16.2 0.1 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 WW PF00397.26 EWM25452.1 - 1.8e-12 47.1 1.8 4.1e-12 46.0 1.8 1.7 1 0 0 1 1 1 1 WW domain WD40 PF00400.32 EWM25452.1 - 1.3e-08 35.3 13.1 0.25 12.3 0.3 6.0 5 0 0 5 5 5 5 WD domain, G-beta repeat Sec16_C PF12931.7 EWM25452.1 - 6.6e-08 32.6 0.4 3.7e-07 30.1 0.4 2.2 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 TFIIA PF03153.13 EWM25452.1 - 5.4 6.9 21.4 10 6.0 21.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.32 EWM25454.1 - 3.5e-23 81.4 13.2 2.3e-05 25.1 0.1 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM25454.1 - 5.6e-07 29.8 0.1 0.55 10.6 0.0 4.0 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EWM25454.1 - 0.017 13.6 0.1 2.3 6.6 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain DUF2630 PF10944.8 EWM25454.1 - 0.16 12.5 0.1 0.35 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) adh_short_C2 PF13561.6 EWM25456.1 - 2.5e-46 158.1 1.9 5.4e-39 134.1 0.1 3.6 2 2 1 3 3 3 3 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EWM25456.1 - 1.8e-35 122.2 3.0 5.4e-33 114.1 0.3 3.1 2 2 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 EWM25456.1 - 5.6e-15 55.7 0.6 8.6e-14 51.8 0.6 2.6 1 1 0 1 1 1 1 KR domain GYD PF08734.11 EWM25456.1 - 0.03 14.3 0.0 7.3 6.6 0.1 3.5 3 1 0 3 3 3 0 GYD domain CHASE2 PF05226.11 EWM25456.1 - 0.066 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 CHASE2 domain Epimerase PF01370.21 EWM25456.1 - 0.078 12.4 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family CBS PF00571.28 EWM25457.1 - 9.1e-14 51.6 0.2 2.7e-08 34.1 0.3 2.5 2 0 0 2 2 2 2 CBS domain SpoIIE PF07228.12 EWM25457.1 - 4.3e-10 39.8 0.0 4.3e-09 36.6 0.0 2.4 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 EWM25457.1 - 4.3e-05 23.3 0.1 0.067 12.8 0.0 2.5 2 0 0 2 2 2 2 Protein phosphatase 2C ARID PF01388.21 EWM25458.1 - 0.18 12.5 0.0 3.3 8.4 0.0 2.7 2 1 0 2 2 2 0 ARID/BRIGHT DNA binding domain Hydrolase_4 PF12146.8 EWM25459.1 - 4.2e-14 52.4 0.1 6.7e-11 41.9 0.1 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EWM25459.1 - 1.8e-06 27.8 0.0 2.6e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EWM25459.1 - 1.9e-06 27.7 0.0 3.5e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 EWM25459.1 - 3.7e-06 27.7 2.8 7.3e-06 26.7 2.8 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family zf-RanBP PF00641.18 EWM25459.1 - 1.2e-05 24.5 1.8 2.5e-05 23.5 1.8 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Peptidase_S9 PF00326.21 EWM25459.1 - 3.5e-05 23.4 0.0 0.00031 20.3 0.0 2.3 2 1 0 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.13 EWM25459.1 - 0.0038 16.9 0.0 0.007 16.0 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) PhoPQ_related PF10142.9 EWM25459.1 - 0.0095 14.6 0.0 0.013 14.2 0.0 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Abhydrolase_3 PF07859.13 EWM25459.1 - 0.021 14.7 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 EWM25459.1 - 0.21 11.1 0.0 22 4.5 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family FBPase PF00316.20 EWM25460.1 - 1.3e-51 174.7 2.4 2.7e-50 170.5 2.4 2.4 1 1 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Eapp_C PF10238.9 EWM25461.1 - 8.1e-11 42.2 0.2 2.4e-10 40.7 0.2 1.7 1 1 0 1 1 1 1 E2F-associated phosphoprotein eIF-1a PF01176.19 EWM25462.1 - 1.9e-22 78.8 0.2 2.7e-22 78.4 0.2 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 RsgA_N PF16745.5 EWM25462.1 - 0.0037 17.0 0.2 0.0067 16.1 0.1 1.5 1 1 0 1 1 1 1 RsgA N-terminal domain Histone PF00125.24 EWM25465.1 - 1e-18 67.9 0.0 1.3e-18 67.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.13 EWM25465.1 - 0.00098 19.6 0.0 0.0016 18.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 EWM25465.1 - 0.023 15.0 0.0 0.048 14.0 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Peptidase_M17 PF00883.21 EWM25466.1 - 2.9e-96 322.4 0.3 1.7e-95 319.9 0.1 1.9 2 0 0 2 2 2 1 Cytosol aminopeptidase family, catalytic domain Pdase_M17_N2 PF18295.1 EWM25466.1 - 1.5e-15 57.5 0.0 4.2e-15 56.1 0.0 1.9 1 0 0 1 1 1 1 M17 aminopeptidase N-terminal domain 2 TAFII28 PF04719.14 EWM25467.1 - 0.056 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Thioredoxin PF00085.20 EWM25468.1 - 1.7e-10 40.8 0.0 3.9e-08 33.2 0.0 3.3 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_6 PF13848.6 EWM25468.1 - 5.8e-06 26.3 0.0 0.0015 18.4 0.0 3.3 4 0 0 4 4 4 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EWM25468.1 - 0.0012 18.3 0.0 0.008 15.6 0.0 2.3 3 0 0 3 3 3 1 OST3 / OST6 family, transporter family DUF836 PF05768.14 EWM25468.1 - 0.01 16.2 0.0 0.03 14.7 0.0 1.8 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 EWM25468.1 - 0.014 15.8 0.0 3.8 8.0 0.0 3.1 2 1 0 2 2 2 0 Thioredoxin-like domain TraF PF13728.6 EWM25468.1 - 0.08 12.8 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 F plasmid transfer operon protein DUF3486 PF11985.8 EWM25468.1 - 3.7 7.9 11.5 2.4 8.5 5.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3486) SecA_DEAD PF07517.14 EWM25469.1 - 4.4e-107 357.7 1.3 4.9e-107 357.5 0.0 1.7 2 0 0 2 2 2 1 SecA DEAD-like domain SecA_SW PF07516.13 EWM25469.1 - 1.8e-35 122.8 8.4 3.5e-35 121.9 8.4 1.5 1 0 0 1 1 1 1 SecA Wing and Scaffold domain SecA_PP_bind PF01043.20 EWM25469.1 - 3.1e-27 95.4 1.1 9.9e-27 93.8 0.0 2.5 3 0 0 3 3 3 1 SecA preprotein cross-linking domain DEAD PF00270.29 EWM25469.1 - 0.00019 21.2 0.1 0.0011 18.8 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EWM25469.1 - 0.05 14.0 1.5 0.38 11.1 0.0 2.8 2 0 0 2 2 2 0 Helicase conserved C-terminal domain FTA4 PF13093.6 EWM25469.1 - 0.075 12.9 0.7 0.6 10.0 0.1 2.4 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF4497 PF14924.6 EWM25469.1 - 0.14 12.6 0.0 0.42 11.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4497) DBI_PRT PF02277.17 EWM25471.1 - 2.3e-96 322.9 7.4 6.8e-58 196.4 7.1 2.0 1 1 1 2 2 2 2 Phosphoribosyltransferase AAA_16 PF13191.6 EWM25471.1 - 0.17 12.2 0.4 0.75 10.2 0.1 2.2 3 0 0 3 3 3 0 AAA ATPase domain FAD_binding_3 PF01494.19 EWM25472.1 - 1.2e-11 44.5 0.6 4.1e-10 39.4 0.6 2.6 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 EWM25472.1 - 1.2e-05 24.4 0.0 0.15 10.9 0.0 2.8 2 1 0 2 2 2 2 Tryptophan halogenase DAO PF01266.24 EWM25472.1 - 2.7e-05 23.9 0.4 0.0033 17.0 0.0 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EWM25472.1 - 3.3e-05 23.3 0.1 5.8e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EWM25472.1 - 4.1e-05 23.0 0.0 0.00023 20.5 0.0 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 EWM25472.1 - 0.00026 21.2 0.0 0.0011 19.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EWM25472.1 - 0.0013 17.9 0.1 0.027 13.5 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 EWM25472.1 - 0.0037 17.3 0.0 0.71 9.8 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 EWM25472.1 - 0.016 13.9 0.0 0.025 13.3 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 EWM25472.1 - 0.019 14.1 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 EWM25472.1 - 0.021 14.2 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase MiaE_2 PF13794.6 EWM25472.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like UQ_con PF00179.26 EWM25474.1 - 7.7e-26 90.4 0.0 1.2e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EWM25474.1 - 0.038 14.3 0.1 0.064 13.5 0.1 1.4 1 0 0 1 1 1 0 RWD domain CobS PF02654.15 EWM25475.1 - 1.6e-39 136.2 14.7 2.1e-39 135.9 14.7 1.1 1 0 0 1 1 1 1 Cobalamin-5-phosphate synthase DnaJ PF00226.31 EWM25476.1 - 1.9e-16 59.9 0.0 3.6e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain TFCD_C PF12612.8 EWM25478.1 - 1.9e-32 112.6 0.6 1.2e-31 110.0 0.0 2.8 3 1 0 3 3 3 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 EWM25478.1 - 2.9e-07 30.2 25.7 0.11 12.8 0.0 11.2 11 0 0 11 11 11 2 HEAT repeat HEAT_2 PF13646.6 EWM25478.1 - 0.014 15.8 23.4 0.2 12.0 0.1 7.0 6 1 1 7 7 7 0 HEAT repeats Cnd1 PF12717.7 EWM25478.1 - 0.067 13.2 0.3 7.2 6.6 0.0 3.5 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EWM25478.1 - 0.23 12.0 0.0 0.23 12.0 0.0 10.2 9 3 2 11 11 11 0 HEAT-like repeat RtcB PF01139.17 EWM25480.1 - 5.6e-148 493.5 0.1 6.5e-148 493.3 0.1 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB SWIB PF02201.18 EWM25482.1 - 4e-50 167.6 0.0 3.3e-26 91.0 0.0 2.4 2 0 0 2 2 2 2 SWIB/MDM2 domain DEK_C PF08766.11 EWM25482.1 - 4.5e-12 45.7 0.3 1.2e-11 44.4 0.3 1.8 1 0 0 1 1 1 1 DEK C terminal domain Peptidase_M18 PF02127.15 EWM25484.1 - 4e-114 381.8 0.0 6.3e-114 381.1 0.0 1.2 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) PDZ PF00595.24 EWM25485.1 - 0.00024 21.4 0.0 0.00092 19.5 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EWM25485.1 - 0.017 15.4 0.0 0.045 14.1 0.0 1.6 2 0 0 2 2 2 0 PDZ domain PDZ_6 PF17820.1 EWM25485.1 - 0.017 14.9 0.1 0.017 14.9 0.1 2.2 2 1 0 2 2 2 0 PDZ domain DUF3006 PF11213.8 EWM25485.1 - 0.21 11.9 0.0 0.64 10.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) DUF1664 PF07889.12 EWM25486.1 - 0.0016 18.5 2.8 0.0016 18.5 2.8 3.5 2 1 0 3 3 3 1 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 EWM25486.1 - 0.0072 16.8 8.9 2.5 8.6 0.3 4.6 4 1 1 5 5 5 2 Nucleopolyhedrovirus P10 protein CHD5 PF04420.14 EWM25486.1 - 0.12 12.2 0.2 0.12 12.2 0.2 3.2 2 1 0 3 3 3 0 CHD5-like protein DUF4358 PF14270.6 EWM25486.1 - 3.4 8.0 5.8 1.7 9.0 0.4 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4358) DUF4407 PF14362.6 EWM25486.1 - 5.4 6.3 30.5 8.5 5.6 10.5 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Ntox1 PF15500.6 EWM25486.1 - 9.6 6.6 9.9 8 6.9 1.3 3.6 1 1 2 3 3 3 0 Putative RNase-like toxin, toxin_1 La PF05383.17 EWM25487.1 - 8.3e-17 61.0 0.0 1.7e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 EWM25487.1 - 1.2e-13 50.6 0.4 1.4e-07 31.3 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EWM25487.1 - 1.2e-10 41.3 0.2 8.1e-07 29.0 0.1 2.6 2 0 0 2 2 2 2 RNA binding motif RRM_occluded PF16842.5 EWM25487.1 - 0.012 15.5 0.0 0.057 13.3 0.0 2.0 2 0 0 2 2 2 0 Occluded RNA-recognition motif PHM7_cyt PF14703.6 EWM25487.1 - 0.086 13.1 0.6 1.2 9.3 0.0 2.8 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Microcin PF03526.13 EWM25488.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Colicin E1 (microcin) immunity protein Myb_DNA-binding PF00249.31 EWM25490.1 - 1e-27 96.0 0.4 2.2e-13 50.2 0.3 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EWM25490.1 - 2.2e-19 69.4 0.4 2.2e-14 53.4 0.0 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EWM25490.1 - 0.00031 20.6 0.0 0.00031 20.6 0.0 2.1 3 0 0 3 3 3 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 EWM25490.1 - 0.009 16.4 0.0 0.051 14.0 0.0 2.2 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain SLIDE PF09111.10 EWM25490.1 - 0.04 13.9 3.0 0.08 13.0 0.0 2.3 2 0 0 2 2 2 0 SLIDE SNF2_N PF00176.23 EWM25491.1 - 1.8e-55 188.1 1.3 8.7e-26 90.5 0.2 3.6 3 1 1 4 4 4 3 SNF2 family N-terminal domain Helicase_C PF00271.31 EWM25491.1 - 2e-16 60.3 0.0 1e-15 58.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-PARP PF00645.18 EWM25491.1 - 1.7e-10 41.6 1.0 7.8e-10 39.5 0.0 2.6 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-C3HC4_3 PF13920.6 EWM25491.1 - 0.00089 19.1 6.8 0.00089 19.1 6.8 2.6 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) ERCC3_RAD25_C PF16203.5 EWM25491.1 - 0.0029 16.9 0.0 0.0059 15.8 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase zf-C3HC4_4 PF15227.6 EWM25491.1 - 0.0038 17.3 9.8 0.014 15.5 9.8 2.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 EWM25491.1 - 0.0042 16.9 7.6 0.0042 16.9 7.6 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_4 PF13717.6 EWM25491.1 - 0.28 11.1 4.9 15 5.6 0.3 3.5 3 0 0 3 3 3 0 zinc-ribbon domain Rep_fac-A_C PF08646.10 EWM25491.1 - 0.41 10.4 3.5 3.2 7.5 0.1 2.6 2 0 0 2 2 2 0 Replication factor-A C terminal domain zf-C3HC4_2 PF13923.6 EWM25491.1 - 9.5 6.2 16.0 0.14 12.1 7.6 2.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.26 EWM25491.1 - 9.5 6.9 10.0 0.3 11.6 0.4 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type FYVE PF01363.21 EWM25492.1 - 2.1e-12 47.0 1.2 4.3e-12 46.0 1.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger Synaptobrevin PF00957.21 EWM25492.1 - 7.6e-06 25.6 0.1 1.4e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 Synaptobrevin FYVE_2 PF02318.16 EWM25492.1 - 0.00013 22.2 0.8 0.0003 21.0 0.8 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger Cullin PF00888.22 EWM25493.1 - 1.1e-175 585.9 0.0 1.3e-175 585.6 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EWM25493.1 - 2.5e-21 75.5 0.4 5.4e-21 74.4 0.4 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain Herpes_TK PF00693.18 EWM25493.1 - 0.24 10.6 0.6 0.44 9.7 0.1 1.6 2 0 0 2 2 2 0 Thymidine kinase from herpesvirus Pkinase PF00069.25 EWM25494.1 - 1.9e-45 155.3 0.0 3.3e-43 147.9 0.0 3.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM25494.1 - 3.7e-27 95.3 0.1 3.5e-18 65.8 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 EWM25494.1 - 0.0019 17.6 0.1 0.016 14.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EWM25494.1 - 0.022 14.7 2.5 1.9 8.3 0.1 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family Uds1 PF15456.6 EWM25494.1 - 0.1 12.8 0.2 0.36 11.0 0.2 1.9 1 0 0 1 1 1 0 Up-regulated During Septation CTP_transf_like PF01467.26 EWM25495.1 - 5.7e-10 39.6 0.0 2.3e-09 37.6 0.0 1.8 1 1 0 1 1 1 1 Cytidylyltransferase-like DUF1180 PF06679.12 EWM25496.1 - 0.084 13.3 0.2 0.2 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF1180 PF06679.12 EWM25497.1 - 0.091 13.2 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) PKD_channel PF08016.12 EWM25497.1 - 0.2 10.3 0.3 0.34 9.5 0.3 1.3 1 0 0 1 1 1 0 Polycystin cation channel LMBR1 PF04791.16 EWM25498.1 - 4.8e-84 283.1 1.3 6.1e-84 282.7 1.3 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein PT PF04886.12 EWM25499.1 - 0.0017 17.9 18.2 0.0017 17.9 18.2 4.3 5 1 1 6 6 6 2 PT repeat Holin_9 PF16936.5 EWM25499.1 - 0.11 12.6 1.0 0.91 9.7 0.6 2.2 2 0 0 2 2 2 0 Putative holin Ribosomal_L4 PF00573.22 EWM25502.1 - 4.4e-36 124.4 0.1 4.4e-36 124.4 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 EWM25502.1 - 6.8e-26 90.1 1.4 6.8e-26 90.1 1.4 1.8 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain FAD-oxidase_C PF02913.19 EWM25503.1 - 5e-57 193.4 0.0 6.5e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EWM25503.1 - 9.5e-36 122.6 3.9 3.5e-35 120.8 0.3 2.4 2 0 0 2 2 2 1 FAD binding domain 2-oxoacid_dh PF00198.23 EWM25504.1 - 1.1e-65 221.4 0.0 1.6e-65 220.8 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EWM25504.1 - 2.8e-18 65.5 0.5 5.6e-18 64.5 0.2 1.7 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 EWM25504.1 - 7.2e-16 58.2 0.5 2.1e-15 56.8 0.5 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 EWM25504.1 - 0.083 12.7 2.1 0.84 9.5 0.6 2.6 2 0 0 2 2 2 0 Biotin-lipoyl like Aspzincin_M35 PF14521.6 EWM25505.1 - 0.036 14.6 0.2 0.19 12.3 0.1 2.3 2 0 0 2 2 2 0 Lysine-specific metallo-endopeptidase Mce4_CUP1 PF11887.8 EWM25505.1 - 0.042 13.3 0.1 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative Ribosomal_S3Ae PF01015.18 EWM25506.1 - 3.6e-83 278.1 1.8 4.3e-83 277.9 1.8 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family FSH1 PF03959.13 EWM25507.1 - 6.6e-37 127.2 0.0 1.1e-36 126.5 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) LIP PF03583.14 EWM25507.1 - 0.17 11.2 0.0 0.65 9.3 0.0 1.7 2 0 0 2 2 2 0 Secretory lipase SAP130_C PF16014.5 EWM25507.1 - 5.5 6.0 8.1 7.4 5.6 8.1 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus ubiquitin PF00240.23 EWM25509.1 - 1.1e-07 31.5 0.0 1.9e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin family SF3A2 PF16835.5 EWM25510.1 - 8.2e-37 125.5 0.0 1.3e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 EWM25510.1 - 5.8e-07 29.7 1.3 1.3e-06 28.6 1.3 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 EWM25510.1 - 0.031 14.2 0.1 0.063 13.2 0.1 1.4 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein Coatomer_WDAD PF04053.14 EWM25511.1 - 3.5e-150 500.9 0.0 8.5e-150 499.7 0.0 1.6 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 EWM25511.1 - 1.3e-30 105.0 9.9 2.4e-08 34.5 0.1 8.5 9 0 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM25511.1 - 5.7e-06 26.6 0.1 0.59 10.5 0.0 5.8 4 2 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain TFIIA PF03153.13 EWM25511.1 - 4.4 7.2 11.9 6.2 6.7 11.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DLH PF01738.18 EWM25513.1 - 1.2e-22 80.5 0.0 1.4e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Pkinase PF00069.25 EWM25514.1 - 1.5e-08 34.3 0.0 2e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain zf-RING_2 PF13639.6 EWM25515.1 - 5.3e-10 39.5 10.1 1.5e-09 38.0 10.1 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EWM25515.1 - 2.1e-06 27.5 9.6 2.1e-06 27.5 9.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EWM25515.1 - 2.9e-06 27.5 8.9 1.1e-05 25.6 8.9 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EWM25515.1 - 4.9e-05 23.0 8.9 4.9e-05 23.0 8.9 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 EWM25515.1 - 0.00023 20.9 6.2 0.00068 19.4 6.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EWM25515.1 - 0.00033 20.5 8.5 0.00079 19.2 8.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EWM25515.1 - 0.015 14.9 7.3 0.028 14.0 7.3 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 EWM25515.1 - 0.1 12.6 8.6 0.21 11.6 8.6 1.6 1 0 0 1 1 1 0 zinc-RING finger domain FANCL_C PF11793.8 EWM25515.1 - 0.23 11.7 6.3 1 9.6 6.3 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 EWM25515.1 - 0.85 9.8 7.0 2.1 8.5 7.0 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Acetyltransf_1 PF00583.25 EWM25517.1 - 5.6e-15 55.6 0.0 8.3e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EWM25517.1 - 4.2e-11 42.9 0.0 6.8e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EWM25517.1 - 3.7e-10 40.1 0.0 6.3e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EWM25517.1 - 1.5e-06 28.1 0.0 2.7e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EWM25517.1 - 2.3e-05 25.1 0.0 3.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EWM25517.1 - 0.00013 22.0 0.1 0.0042 17.2 0.0 2.4 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 EWM25517.1 - 0.00036 20.7 0.0 0.00076 19.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PCP_red PF08369.10 EWM25517.1 - 0.00082 19.5 0.0 0.031 14.5 0.1 2.5 2 0 0 2 2 2 1 Proto-chlorophyllide reductase 57 kD subunit Acetyltransf_9 PF13527.7 EWM25517.1 - 0.074 13.1 0.1 0.18 11.9 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EWM25517.1 - 0.089 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase 2HCT PF03390.15 EWM25517.1 - 0.13 10.8 0.2 0.19 10.3 0.2 1.1 1 0 0 1 1 1 0 2-hydroxycarboxylate transporter family AAA_11 PF13086.6 EWM25518.1 - 2e-62 211.3 0.1 2e-62 211.3 0.1 2.4 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.6 EWM25518.1 - 9.6e-56 188.6 0.0 1.7e-55 187.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain SEN1_N PF12726.7 EWM25518.1 - 7.8e-10 37.6 0.0 5.8e-09 34.8 0.0 2.0 1 1 0 1 1 1 1 SEN1 N terminal AAA_19 PF13245.6 EWM25518.1 - 4.2e-08 33.6 0.0 6.3e-07 29.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EWM25518.1 - 2.9e-06 27.2 0.0 0.06 13.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain Med26 PF08711.11 EWM25518.1 - 4.5e-05 23.4 0.8 0.00015 21.7 0.8 2.0 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Viral_helicase1 PF01443.18 EWM25518.1 - 8.1e-05 22.5 0.0 0.23 11.1 0.0 3.7 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 EWM25518.1 - 0.0079 16.2 0.0 0.028 14.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EWM25518.1 - 0.014 15.8 0.1 0.23 11.9 0.0 3.1 2 0 0 2 2 2 0 AAA ATPase domain DUF3734 PF12536.8 EWM25518.1 - 0.086 13.2 0.2 0.56 10.6 0.1 2.3 2 0 0 2 2 2 0 Patatin phospholipase AAA PF00004.29 EWM25518.1 - 0.13 12.6 0.0 2.8 8.4 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MAPEG PF01124.18 EWM25519.1 - 3.5e-13 49.6 5.3 6.1e-13 48.8 5.3 1.4 1 1 0 1 1 1 1 MAPEG family BCDHK_Adom3 PF10436.9 EWM25519.1 - 0.12 12.2 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase TPR_2 PF07719.17 EWM25520.1 - 6.1e-25 85.3 24.6 0.00081 19.3 0.0 9.6 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_1 PF00515.28 EWM25520.1 - 2.3e-21 74.7 9.0 9e-05 22.1 0.0 8.4 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 EWM25520.1 - 2.8e-16 58.3 0.0 0.0017 18.4 0.0 6.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 EWM25520.1 - 1.8e-14 52.6 10.5 4.5e-05 23.2 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 EWM25520.1 - 1.3e-09 37.6 2.3 0.038 13.7 0.0 4.9 4 1 1 5 5 4 3 TPR repeat TPR_12 PF13424.6 EWM25520.1 - 1.3e-07 31.8 0.4 1.3e-07 31.8 0.4 8.0 7 1 2 9 9 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 EWM25520.1 - 9.6e-07 29.4 29.1 0.00019 22.0 0.3 7.7 5 2 1 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 EWM25520.1 - 1.7e-06 28.0 0.0 4.1 8.0 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EWM25520.1 - 7.2e-06 26.4 35.1 0.71 10.9 0.6 9.7 6 4 4 10 10 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EWM25520.1 - 0.0002 21.5 19.2 0.063 13.5 0.0 6.1 4 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 EWM25520.1 - 0.0018 18.4 0.3 1.1 9.3 0.0 3.2 2 0 0 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_10 PF13374.6 EWM25520.1 - 0.0081 16.0 0.1 0.0081 16.0 0.1 7.4 8 1 1 9 9 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 EWM25520.1 - 0.03 14.8 0.0 0.03 14.8 0.0 6.1 6 1 0 7 7 6 0 Tetratricopeptide repeat Glyoxalase PF00903.25 EWM25520.1 - 0.067 13.4 0.0 15 5.8 0.0 2.9 2 1 1 3 3 3 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TPR_9 PF13371.6 EWM25520.1 - 0.11 12.7 0.2 0.11 12.7 0.2 5.6 7 2 1 8 8 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 EWM25520.1 - 0.78 10.6 25.0 5.6 7.9 0.0 7.1 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EWM25520.1 - 1.1 10.0 17.6 4.9 8.0 0.2 7.4 8 0 0 8 8 7 0 Tetratricopeptide repeat Sel1 PF08238.12 EWM25520.1 - 5 7.9 14.3 20 6.1 0.1 5.5 6 0 0 6 6 5 0 Sel1 repeat GCIP PF13324.6 EWM25521.1 - 5.8e-24 85.1 0.0 7.4e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting Nop25 PF09805.9 EWM25521.1 - 0.24 11.9 3.5 0.38 11.2 3.5 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) ArgJ PF01960.18 EWM25522.1 - 8.7e-102 340.6 0.0 1.2e-101 340.2 0.0 1.1 1 0 0 1 1 1 1 ArgJ family SR-25 PF10500.9 EWM25522.1 - 0.045 13.4 5.5 0.071 12.7 5.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Glyoxalase PF00903.25 EWM25524.1 - 0.0086 16.3 0.0 0.03 14.5 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EWM25524.1 - 0.017 15.9 0.0 0.022 15.5 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain Kazal_1 PF00050.21 EWM25526.1 - 9.5e-19 67.1 49.2 3.3e-06 27.0 6.1 6.2 5 0 0 5 5 5 5 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 EWM25526.1 - 4.8e-11 42.6 59.0 0.0002 21.4 3.0 7.0 8 0 0 8 8 8 5 Kazal-type serine protease inhibitor domain Lactamase_B_6 PF16661.5 EWM25527.1 - 9.1e-43 145.9 0.0 1.3e-42 145.5 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 EWM25527.1 - 2.2e-15 56.9 0.0 4.7e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain CPSF100_C PF13299.6 EWM25527.1 - 3.7e-07 30.5 0.0 1.1e-06 29.0 0.0 1.6 1 1 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal RMMBL PF07521.12 EWM25527.1 - 0.00024 21.0 0.0 0.00051 19.9 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 EWM25527.1 - 0.021 14.4 0.0 0.049 13.1 0.0 1.7 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 EWM25527.1 - 0.3 10.3 0.0 0.68 9.1 0.0 1.5 1 0 0 1 1 1 0 Putative beta-lactamase-like family Mpv17_PMP22 PF04117.12 EWM25529.1 - 3.3e-22 78.5 0.5 5.4e-22 77.8 0.5 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family zf-C3HC4_3 PF13920.6 EWM25530.1 - 1.7e-12 47.0 15.6 3.1e-12 46.1 15.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EWM25530.1 - 5.6e-07 29.3 15.1 1.1e-06 28.4 15.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EWM25530.1 - 5.1e-05 23.5 15.4 0.00011 22.5 15.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EWM25530.1 - 0.015 15.2 14.9 0.03 14.3 14.9 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.6 EWM25530.1 - 1.8 8.4 14.0 3.8 7.4 14.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TRAM_LAG1_CLN8 PF03798.16 EWM25533.1 - 0.023 14.5 22.7 0.042 13.6 22.7 1.5 1 1 0 1 1 1 0 TLC domain DUF543 PF04418.12 EWM25533.1 - 0.054 13.5 1.0 0.1 12.6 0.1 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF543) Apt1 PF10351.9 EWM25535.1 - 3e-09 36.3 7.4 2.6e-05 23.3 0.1 3.9 3 2 1 4 4 4 2 Golgi-body localisation protein domain BTK PF00779.19 EWM25535.1 - 1.4e-05 24.8 2.9 3e-05 23.7 2.9 1.5 1 0 0 1 1 1 1 BTK motif HIT PF01230.23 EWM25536.1 - 5e-23 81.7 0.3 8.3e-23 81.0 0.3 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EWM25536.1 - 4.5e-07 30.3 0.2 7.2e-07 29.7 0.2 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GTP_EFTU PF00009.27 EWM25537.1 - 7.2e-24 84.4 0.2 3.2e-17 62.7 0.3 3.3 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EWM25537.1 - 3.4e-18 65.7 0.0 6.7e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 EWM25537.1 - 1.8e-07 31.2 0.0 4.3e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Glyco_trans_1_2 PF13524.6 EWM25537.1 - 0.032 14.6 0.2 0.096 13.1 0.2 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 Dynamin_N PF00350.23 EWM25537.1 - 0.034 14.2 0.0 0.35 10.9 0.0 2.4 2 0 0 2 2 2 0 Dynamin family Roc PF08477.13 EWM25537.1 - 0.058 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EWM25537.1 - 0.13 12.1 0.0 0.58 9.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain IF2_N PF04760.15 EWM25537.1 - 0.14 12.0 0.0 0.98 9.3 0.0 2.5 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region PduV-EutP PF10662.9 EWM25537.1 - 0.18 11.5 0.0 3 7.6 0.0 2.7 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation zf-RING_2 PF13639.6 EWM25539.1 - 5.8e-11 42.6 6.7 5.8e-11 42.6 6.7 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 EWM25539.1 - 1.4e-07 31.1 1.9 3.6e-07 29.8 1.9 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 EWM25539.1 - 3.8e-05 23.9 10.0 0.00015 22.0 10.0 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EWM25539.1 - 0.00011 21.9 7.2 0.00011 21.9 7.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EWM25539.1 - 0.0037 17.2 6.2 0.0037 17.2 6.2 1.9 3 0 0 3 3 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EWM25539.1 - 0.0048 16.7 6.4 0.0048 16.7 6.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EWM25539.1 - 0.015 15.3 2.1 0.015 15.3 2.1 1.8 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EWM25539.1 - 0.11 12.4 10.7 0.023 14.6 5.2 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 EWM25539.1 - 0.36 11.0 7.5 0.74 10.0 7.5 1.5 1 0 0 1 1 1 0 RING-variant domain SDA1 PF05285.12 EWM25539.1 - 0.45 9.9 13.5 0.73 9.2 13.5 1.2 1 0 0 1 1 1 0 SDA1 zf-RING_4 PF14570.6 EWM25539.1 - 0.55 10.1 5.8 1.2 9.0 5.8 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 EWM25539.1 - 0.79 9.9 4.4 1.9 8.8 4.4 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain DNA_pol_phi PF04931.13 EWM25539.1 - 4.8 5.1 16.2 6.8 4.7 16.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 EWM25539.1 - 7.9 4.6 16.2 11 4.0 16.2 1.1 1 0 0 1 1 1 0 Nop14-like family SNF2_N PF00176.23 EWM25540.1 - 7.3e-28 97.3 0.0 9.6e-28 96.9 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 EWM25540.1 - 1.8e-07 31.1 0.0 2.3e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EWM25540.1 - 2.5e-06 27.6 0.0 3.2e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD_2 PF06733.15 EWM25540.1 - 0.0082 15.8 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 DEAD_2 AAA PF00004.29 EWM25540.1 - 0.0092 16.4 0.0 0.25 11.8 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EWM25540.1 - 0.047 13.3 0.2 0.095 12.3 0.2 1.5 1 1 0 1 1 1 0 AAA domain Terminase_1 PF03354.15 EWM25540.1 - 0.13 10.8 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Phage Terminase CobA_CobO_BtuR PF02572.15 EWM25540.1 - 0.14 12.5 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP DUF498 PF04430.14 EWM25540.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) AAA_22 PF13401.6 EWM25540.1 - 0.17 12.2 0.0 0.46 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain NUP50 PF08911.11 EWM25542.1 - 1.1e-11 45.2 1.7 4.3e-11 43.3 1.7 2.1 1 0 0 1 1 1 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.18 EWM25542.1 - 1.6e-05 25.2 0.0 2.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain RRF PF01765.19 EWM25543.1 - 6.7e-47 159.4 0.0 8.4e-47 159.1 0.0 1.1 1 0 0 1 1 1 1 Ribosome recycling factor HNH PF01844.23 EWM25544.1 - 4.3e-07 30.0 0.1 4.3e-07 30.0 0.1 2.8 3 0 0 3 3 3 1 HNH endonuclease HNH_5 PF14279.6 EWM25544.1 - 0.00068 19.4 0.2 0.053 13.4 0.0 2.8 2 0 0 2 2 2 1 HNH endonuclease SR-25 PF10500.9 EWM25545.1 - 0.028 14.0 6.4 0.048 13.3 6.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein GAF_2 PF13185.6 EWM25546.1 - 0.0014 19.0 0.8 0.049 13.9 0.0 2.9 2 1 1 3 3 3 1 GAF domain zf-RING_2 PF13639.6 EWM25547.1 - 1.1e-14 54.5 5.1 1.4e-14 54.1 5.1 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EWM25547.1 - 2.4e-12 46.5 4.2 3.8e-12 45.9 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EWM25547.1 - 2.5e-10 39.9 3.9 6.7e-10 38.5 0.9 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 EWM25547.1 - 3.6e-10 40.0 3.4 6e-10 39.3 3.4 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EWM25547.1 - 9.2e-09 35.0 3.9 1.3e-08 34.5 3.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EWM25547.1 - 4.7e-08 32.8 3.3 6.7e-08 32.3 3.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EWM25547.1 - 1.1e-07 31.6 3.1 1.6e-07 31.1 3.1 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EWM25547.1 - 5e-07 29.6 3.9 7.5e-07 29.0 3.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EWM25547.1 - 7.2e-07 29.1 3.5 7.3e-06 25.9 0.4 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EWM25547.1 - 1.4e-05 25.0 0.2 1.9e-05 24.6 0.2 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EWM25547.1 - 3.2e-05 23.5 4.3 5.9e-05 22.6 4.3 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Vps39_2 PF10367.9 EWM25547.1 - 0.00011 22.6 3.2 0.00013 22.4 0.6 2.1 2 1 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 RINGv PF12906.7 EWM25547.1 - 0.0019 18.2 3.3 0.0044 17.1 3.3 1.6 1 1 0 1 1 1 1 RING-variant domain Prok-RING_1 PF14446.6 EWM25547.1 - 0.0036 17.2 4.0 0.3 11.0 1.3 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-RING-like PF08746.11 EWM25547.1 - 0.004 17.4 5.1 0.0059 16.9 5.1 1.3 1 0 0 1 1 1 1 RING-like domain PHD PF00628.29 EWM25547.1 - 0.0043 16.9 3.6 0.015 15.2 3.6 1.8 1 1 1 2 2 2 1 PHD-finger zf-RING_4 PF14570.6 EWM25547.1 - 0.0056 16.5 2.7 0.0087 15.8 2.7 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Rtf2 PF04641.12 EWM25547.1 - 0.026 13.9 0.6 0.033 13.5 0.6 1.4 1 1 0 1 1 1 0 Rtf2 RING-finger zf-Nse PF11789.8 EWM25547.1 - 0.045 13.6 2.0 0.067 13.0 2.0 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Rad50_zn_hook PF04423.14 EWM25547.1 - 0.048 13.5 2.6 0.76 9.7 0.2 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif NADH-G_4Fe-4S_3 PF10588.9 EWM25547.1 - 0.074 12.6 2.5 0.29 10.7 0.3 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region zf-HC5HC2H PF13771.6 EWM25547.1 - 0.097 12.9 2.3 0.11 12.8 0.2 1.9 1 1 1 2 2 2 0 PHD-like zinc-binding domain TackOD1 PF18551.1 EWM25547.1 - 0.14 11.8 2.3 0.23 11.1 2.3 1.3 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 FANCL_C PF11793.8 EWM25547.1 - 0.16 12.1 5.3 1.4 9.2 5.3 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain DUF2685 PF10886.8 EWM25547.1 - 0.3 11.3 3.0 0.56 10.4 3.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2685) zf-RING_10 PF16685.5 EWM25547.1 - 0.32 11.2 2.8 0.43 10.7 2.8 1.2 1 0 0 1 1 1 0 zinc RING finger of MSL2 Zf_RING PF16744.5 EWM25547.1 - 0.34 11.0 4.6 1.4 9.1 4.6 1.9 1 1 0 1 1 1 0 KIAA1045 RING finger zf-C3HC4_4 PF15227.6 EWM25547.1 - 0.36 11.0 5.3 2.8 8.2 5.9 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING FHA PF00498.26 EWM25548.1 - 2.2e-18 66.3 0.3 4.2e-18 65.4 0.3 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EWM25548.1 - 8.4e-08 32.4 0.0 3.6e-07 30.4 0.0 2.1 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4 PF00097.25 EWM25548.1 - 2.1e-06 27.5 0.9 2.1e-06 27.5 0.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EWM25548.1 - 7.9e-06 25.6 1.2 7.9e-06 25.6 1.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EWM25548.1 - 0.00049 19.9 0.9 0.00049 19.9 0.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EWM25548.1 - 0.0016 18.7 1.4 0.0016 18.7 1.4 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 EWM25548.1 - 0.002 18.3 2.0 0.0049 17.0 2.0 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EWM25548.1 - 0.0093 16.0 3.1 0.022 14.8 3.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_5 PF17121.5 EWM25548.1 - 0.012 15.4 0.9 0.03 14.2 0.3 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EWM25548.1 - 0.017 15.0 1.0 0.055 13.4 1.0 1.9 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 EWM25548.1 - 0.44 10.4 4.6 1.2 9.0 4.6 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 AAA_13 PF13166.6 EWM25548.1 - 3.3 6.2 15.1 4.5 5.8 15.1 1.1 1 0 0 1 1 1 0 AAA domain Exo84_C PF16528.5 EWM25549.1 - 1.1e-14 54.8 0.1 2.3e-11 43.9 0.0 2.6 3 0 0 3 3 3 2 Exocyst component 84 C-terminal Vps51 PF08700.11 EWM25549.1 - 0.0013 18.8 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 Vps51/Vps67 DUF4763 PF15960.5 EWM25549.1 - 0.078 12.3 0.7 0.13 11.6 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) PE PF00934.20 EWM25549.1 - 0.084 13.2 0.2 0.084 13.2 0.2 2.3 2 0 0 2 2 2 0 PE family COG5 PF10392.9 EWM25549.1 - 0.14 12.4 0.3 0.42 10.8 0.0 1.8 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF1995 PF09353.10 EWM25550.1 - 2e-05 24.7 0.0 3.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) TatD_DNase PF01026.21 EWM25551.1 - 4.9e-39 134.3 0.1 6.2e-39 133.9 0.1 1.1 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 EWM25551.1 - 0.033 14.0 0.0 0.44 10.3 0.0 2.4 2 1 0 2 2 2 0 Amidohydrolase ABC2_membrane PF01061.24 EWM25553.1 - 1.8e-43 148.4 3.9 3.5e-43 147.5 3.9 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EWM25553.1 - 1.8e-21 77.1 0.1 4.7e-21 75.7 0.0 1.7 2 0 0 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.7 EWM25553.1 - 2.4e-06 26.9 3.6 4e-06 26.2 3.6 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_22 PF13401.6 EWM25553.1 - 0.0002 21.6 0.7 0.0017 18.6 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EWM25553.1 - 0.001 19.5 0.1 0.0027 18.1 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EWM25553.1 - 0.0012 18.7 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AFG1_ATPase PF03969.16 EWM25553.1 - 0.0049 15.8 0.0 0.0083 15.1 0.0 1.2 1 0 0 1 1 1 1 AFG1-like ATPase Rad17 PF03215.15 EWM25553.1 - 0.0058 16.6 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain T2SSE PF00437.20 EWM25553.1 - 0.0065 15.6 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_33 PF13671.6 EWM25553.1 - 0.01 16.0 0.4 0.043 14.0 0.1 2.0 1 1 0 2 2 2 0 AAA domain SMC_N PF02463.19 EWM25553.1 - 0.011 15.2 0.0 0.039 13.4 0.0 1.7 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EWM25553.1 - 0.021 14.5 0.2 0.049 13.4 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EWM25553.1 - 0.035 14.2 0.0 0.064 13.3 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 EWM25553.1 - 0.038 13.7 0.1 0.079 12.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EWM25553.1 - 0.04 14.2 0.4 0.23 11.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EWM25553.1 - 0.04 13.8 0.0 0.13 12.1 0.0 1.9 1 0 0 1 1 1 0 NACHT domain AAA_21 PF13304.6 EWM25553.1 - 0.059 13.2 0.3 0.43 10.3 0.2 2.0 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_2 PF12679.7 EWM25553.1 - 0.059 12.6 1.8 0.11 11.8 1.8 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein AAA_23 PF13476.6 EWM25553.1 - 0.075 13.5 0.5 0.12 12.8 0.1 1.5 2 0 0 2 2 1 0 AAA domain cobW PF02492.19 EWM25553.1 - 0.095 12.3 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 EWM25553.1 - 0.17 12.4 0.0 0.36 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain E1_dh PF00676.20 EWM25554.1 - 5.4e-50 170.0 0.1 9.2e-50 169.3 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_C PF02780.20 EWM25554.1 - 3.8e-22 78.5 0.1 1.3e-21 76.8 0.1 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 EWM25554.1 - 1.4e-15 57.4 0.0 3e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain TPP_enzyme_C PF02775.21 EWM25554.1 - 0.00011 22.0 2.2 0.00037 20.3 0.0 2.9 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 EWM25554.1 - 0.096 11.9 0.0 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase SelR PF01641.18 EWM25556.1 - 1.6e-30 105.7 0.0 2.3e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 SelR domain SR-25 PF10500.9 EWM25556.1 - 0.093 12.3 18.1 0.16 11.6 18.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 EWM25556.1 - 0.13 10.4 10.6 0.15 10.1 10.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein IMUP PF15761.5 EWM25556.1 - 3 8.6 13.1 7.6 7.3 13.1 1.7 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF515 PF04415.12 EWM25556.1 - 7 4.9 8.4 9.6 4.5 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) IF4E PF01652.18 EWM25557.1 - 8.2e-32 110.2 0.0 1.2e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E PQ-loop PF04193.14 EWM25558.1 - 2.8e-21 75.1 0.9 3e-11 42.9 0.6 2.8 2 0 0 2 2 2 2 PQ loop repeat T2SSM_b PF10741.9 EWM25558.1 - 0.063 13.1 0.5 2.2 8.1 0.0 2.6 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein M subtype b TruD PF01142.18 EWM25559.1 - 2.3e-07 30.0 0.0 0.015 14.2 0.0 2.1 2 0 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) DUF1180 PF06679.12 EWM25559.1 - 0.098 13.1 0.1 0.14 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) PGF-CTERM PF18204.1 EWM25561.1 - 2 8.5 4.3 4.4 7.4 4.3 1.6 1 0 0 1 1 1 0 PGF-CTERM motif Guanylate_cyc_2 PF09778.9 EWM25562.1 - 1.2e-33 116.3 0.0 1.5e-24 86.6 0.0 3.1 3 0 0 3 3 3 3 Guanylylate cyclase Peptidase_C39 PF03412.15 EWM25562.1 - 0.0043 16.9 0.0 0.0081 16.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase C39 family Peptidase_C39_2 PF13529.6 EWM25562.1 - 0.051 14.1 0.0 7.6 7.1 0.0 2.5 2 0 0 2 2 2 0 Peptidase_C39 like family DUF3357 PF11837.8 EWM25563.1 - 0.06 13.8 0.1 1.8 9.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) RCC1 PF00415.18 EWM25565.1 - 1.3e-13 51.4 3.1 2.4e-06 28.1 0.0 4.3 4 0 0 4 4 3 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EWM25565.1 - 1.4e-06 27.9 5.7 0.00083 19.1 0.4 4.1 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat SPX PF03105.19 EWM25565.1 - 0.0055 16.7 3.9 0.0071 16.3 3.9 1.3 1 0 0 1 1 1 1 SPX domain Hyd_WA PF06462.12 EWM25565.1 - 0.014 15.3 0.5 0.33 11.0 0.3 2.6 2 0 0 2 2 2 0 Propeller Peroxin-3 PF04882.12 EWM25565.1 - 0.14 11.1 2.3 0.19 10.7 2.3 1.1 1 0 0 1 1 1 0 Peroxin-3 NAM-associated PF14303.6 EWM25565.1 - 0.23 12.2 9.3 0.42 11.3 9.3 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Apt1 PF10351.9 EWM25565.1 - 0.31 9.8 8.2 0.41 9.5 8.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain BUD22 PF09073.10 EWM25565.1 - 0.57 9.5 6.0 0.79 9.0 6.0 1.1 1 0 0 1 1 1 0 BUD22 DUF4614 PF15391.6 EWM25565.1 - 0.72 9.8 16.8 1.2 9.1 16.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Macoilin PF09726.9 EWM25565.1 - 0.75 8.3 9.4 0.97 7.9 9.4 1.0 1 0 0 1 1 1 0 Macoilin family Pex14_N PF04695.13 EWM25565.1 - 1.6 9.4 9.7 0.15 12.7 4.0 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Period_C PF12114.8 EWM25565.1 - 2.2 7.8 17.8 3.4 7.2 17.8 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region AF-4 PF05110.13 EWM25565.1 - 2.6 6.0 28.4 3.6 5.5 28.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Secretin_N_2 PF07655.13 EWM25565.1 - 3.4 8.3 22.9 6.6 7.3 22.9 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain RSRP PF17069.5 EWM25565.1 - 5.4 6.5 37.9 0.63 9.6 32.3 1.9 2 0 0 2 2 2 0 Arginine/Serine-Rich protein 1 RCC1 PF00415.18 EWM25566.1 - 8.6e-14 51.9 3.2 2e-06 28.3 0.0 4.2 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EWM25566.1 - 1.3e-05 24.9 9.6 0.0007 19.3 0.4 4.2 5 1 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat Apt1 PF10351.9 EWM25566.1 - 0.12 11.3 6.9 0.15 10.9 6.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain NAM-associated PF14303.6 EWM25566.1 - 0.19 12.4 9.3 0.36 11.5 9.3 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain BUD22 PF09073.10 EWM25566.1 - 0.43 9.9 5.9 0.59 9.4 5.9 1.1 1 0 0 1 1 1 0 BUD22 RSRP PF17069.5 EWM25566.1 - 0.54 9.8 33.1 0.91 9.0 33.1 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 DUF4614 PF15391.6 EWM25566.1 - 0.6 10.1 16.8 0.97 9.4 16.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Peroxin-3 PF04882.12 EWM25566.1 - 0.97 8.3 4.9 1.3 7.9 4.9 1.1 1 0 0 1 1 1 0 Peroxin-3 Pex14_N PF04695.13 EWM25566.1 - 1.1 9.9 9.6 0.12 13.0 4.0 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Secretin_N_2 PF07655.13 EWM25566.1 - 1.2 9.7 21.7 2.4 8.7 21.7 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Period_C PF12114.8 EWM25566.1 - 1.8 8.1 17.8 2.8 7.5 17.8 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region AF-4 PF05110.13 EWM25566.1 - 3.4 5.6 28.7 4.8 5.2 28.7 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Macoilin PF09726.9 EWM25566.1 - 3.6 6.0 11.8 4.8 5.6 11.8 1.0 1 0 0 1 1 1 0 Macoilin family CCDC106 PF15794.5 EWM25566.1 - 8.7 6.0 10.6 13 5.4 10.6 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 RmlD_sub_bind PF04321.17 EWM25568.1 - 1.7e-07 30.7 0.0 5e-06 25.8 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain Epimerase PF01370.21 EWM25568.1 - 3.1e-06 26.9 0.0 1.8e-05 24.3 0.0 1.9 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EWM25568.1 - 7.9e-05 22.3 0.0 0.00012 21.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EWM25568.1 - 0.00079 19.4 0.0 0.0015 18.5 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EWM25568.1 - 0.16 10.9 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DnaJ PF00226.31 EWM25569.1 - 4.1e-21 74.9 1.1 8.3e-21 73.9 1.1 1.5 1 0 0 1 1 1 1 DnaJ domain DUF4460 PF14687.6 EWM25569.1 - 0.071 13.2 0.6 3 7.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4460) Sulfotransfer_3 PF13469.6 EWM25571.1 - 8.6e-06 26.3 0.2 2.9e-05 24.5 0.1 1.9 2 0 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 EWM25571.1 - 5.8e-05 22.7 0.4 0.00052 19.6 0.2 2.1 2 0 0 2 2 2 1 Sulfotransferase domain HTH_16 PF12645.7 EWM25571.1 - 0.28 11.3 1.3 0.6 10.2 1.3 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain YL1 PF05764.13 EWM25571.1 - 5 7.2 25.9 8.2 6.5 25.9 1.3 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 EWM25571.1 - 5.8 5.1 14.0 8 4.6 14.0 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 EWM25571.1 - 8.8 4.8 29.1 12 4.3 29.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.12 EWM25571.1 - 9 5.6 24.9 13 5.1 24.9 1.2 1 0 0 1 1 1 0 SDA1 DUF872 PF05915.12 EWM25573.1 - 0.092 12.9 0.1 0.14 12.3 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) TRAP-gamma PF07074.12 EWM25574.1 - 5.3 6.6 6.7 10 5.7 6.7 1.4 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Glyco_transf_22 PF03901.17 EWM25575.1 - 2.5e-41 142.3 3.7 3.3e-41 141.9 3.7 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF3678 PF12435.8 EWM25575.1 - 0.011 15.1 0.8 0.031 13.6 0.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) Na_Ca_ex PF01699.24 EWM25576.1 - 8.9e-27 93.9 31.3 5e-17 62.2 15.9 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Sulfotransfer_3 PF13469.6 EWM25577.1 - 1.7e-06 28.6 1.8 0.21 12.0 0.0 3.7 1 1 3 4 4 4 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 EWM25577.1 - 2.8e-06 27.0 0.1 7e-06 25.7 0.1 1.9 1 1 0 1 1 1 1 Sulfotransferase domain Gly_transf_sug PF04488.15 EWM25577.1 - 0.14 12.8 0.0 0.38 11.4 0.0 1.7 1 0 0 1 1 1 0 Glycosyltransferase sugar-binding region containing DXD motif DUF3727 PF12527.8 EWM25583.1 - 1.7e-05 24.9 0.3 2.4e-05 24.5 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3727) DUF3727 PF12527.8 EWM25584.1 - 0.0014 18.8 2.0 0.44 10.8 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF3727) TFIIB_C_1 PF18542.1 EWM25590.1 - 0.006 16.6 0.1 0.011 15.7 0.1 1.4 1 0 0 1 1 1 1 Transcription factor IIB C-terminal module 1 Dpoe2NT PF12213.8 EWM25591.1 - 9.3e-10 38.7 0.0 1.3e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerases epsilon N terminal GTP_EFTU PF00009.27 EWM25593.1 - 0.11 12.0 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain CPSF_A PF03178.15 EWM25595.1 - 5.5e-18 65.4 0.0 7.1e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 CPSF A subunit region UbiA PF01040.18 EWM25596.1 - 2e-20 73.1 28.2 2.7e-19 69.5 27.5 2.6 1 1 1 2 2 2 1 UbiA prenyltransferase family WD40_3 PF15911.5 EWM25598.1 - 0.031 14.3 0.0 0.041 13.9 0.0 1.2 1 0 0 1 1 1 0 WD domain, G-beta repeat C5HCH PF17982.1 EWM25601.1 - 0.00013 22.1 7.7 0.00049 20.2 7.7 2.0 1 0 0 1 1 1 1 NSD Cys-His rich domain CDC27 PF09507.10 EWM25601.1 - 0.041 13.3 1.0 0.43 9.9 0.0 2.0 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Ank_2 PF12796.7 EWM25603.1 - 3.8e-11 43.4 0.0 2.5e-05 24.8 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EWM25603.1 - 1e-09 38.7 0.0 0.0023 18.4 0.0 3.3 2 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EWM25603.1 - 1.3e-07 31.8 0.0 0.002 18.4 0.0 4.6 3 2 1 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EWM25603.1 - 3e-06 27.2 0.0 14 6.7 0.0 5.2 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 EWM25603.1 - 0.005 17.2 0.0 1.1 9.8 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeat FAF PF11250.8 EWM25603.1 - 0.016 15.5 0.1 6.4 7.1 0.0 2.8 2 0 0 2 2 2 0 Fantastic Four meristem regulator Fer4_5 PF12801.7 EWM25604.1 - 5.9e-14 51.7 17.4 6e-10 38.9 3.3 2.9 3 0 0 3 3 3 2 4Fe-4S binding domain CTP_transf_1 PF01148.20 EWM25604.1 - 0.04 13.7 1.3 0.05 13.4 1.3 1.1 1 0 0 1 1 1 0 Cytidylyltransferase family PT PF04886.12 EWM25605.1 - 7.8e-14 50.9 158.3 0.0021 17.6 23.6 7.4 2 1 4 6 6 6 4 PT repeat Vint PF14623.6 EWM25605.1 - 1.3e-11 44.6 0.0 2.1e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Hint-domain Hint PF01079.20 EWM25605.1 - 0.031 13.8 0.0 0.1 12.1 0.0 1.7 2 0 0 2 2 2 0 Hint module Rubis-subs-bind PF09273.11 EWM25606.1 - 2.8e-11 44.2 0.0 4.7e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding CSF-1 PF05337.11 EWM25606.1 - 0.024 14.7 0.0 0.031 14.4 0.0 1.2 1 0 0 1 1 1 0 Macrophage colony stimulating factor-1 (CSF-1) zf-HC3 PF16827.5 EWM25606.1 - 0.054 13.7 0.0 0.098 12.9 0.0 1.4 1 0 0 1 1 1 0 zinc-finger SET PF00856.28 EWM25607.1 - 5.3e-13 49.7 0.0 6.8e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 SET domain TauE PF01925.19 EWM25608.1 - 5.8e-11 42.5 1.0 6.1e-11 42.4 1.0 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE UPF0016 PF01169.19 EWM25608.1 - 0.021 15.1 0.9 0.026 14.9 0.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein family UPF0016 TauE PF01925.19 EWM25610.1 - 2.8e-05 23.9 13.8 0.00075 19.2 9.0 2.1 1 1 1 2 2 2 2 Sulfite exporter TauE/SafE PsbX PF06596.11 EWM25610.1 - 0.12 12.4 2.5 0.32 11.0 1.8 2.1 1 1 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) AAA PF00004.29 EWM25611.1 - 2.6e-10 40.9 0.0 4.8e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EWM25611.1 - 1.2e-08 35.3 0.0 2e-07 31.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_lid_10 PF17872.1 EWM25611.1 - 9.5e-08 32.1 0.0 1.8e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 AAA lid domain AAA_16 PF13191.6 EWM25611.1 - 1.5e-07 32.0 0.1 5.6e-07 30.1 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 EWM25611.1 - 0.0029 17.9 0.1 0.01 16.2 0.0 1.9 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 EWM25611.1 - 0.021 14.8 0.0 0.083 12.8 0.0 1.9 1 1 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 EWM25611.1 - 0.023 14.4 0.0 0.055 13.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EWM25611.1 - 0.06 13.1 0.0 0.12 12.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EWM25611.1 - 0.061 12.6 0.0 0.086 12.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.19 EWM25611.1 - 0.074 12.6 0.0 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 EWM25611.1 - 0.16 11.9 0.2 0.5 10.3 0.0 1.9 2 0 0 2 2 2 0 NTPase AAA_7 PF12775.7 EWM25611.1 - 0.22 11.0 0.0 0.36 10.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region MFS_1 PF07690.16 EWM25616.1 - 2.7e-22 79.2 19.8 2.7e-22 79.2 19.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EWM25616.1 - 1e-15 57.5 9.3 1e-15 57.5 9.3 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter DUF1179 PF06678.11 EWM25616.1 - 0.022 14.7 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) PAP2 PF01569.21 EWM25618.1 - 0.0029 17.4 0.1 0.054 13.3 0.0 2.2 2 0 0 2 2 2 1 PAP2 superfamily ZYG-11_interact PF05884.12 EWM25619.1 - 0.059 12.8 1.9 0.16 11.3 1.9 1.7 1 0 0 1 1 1 0 Interactor of ZYG-11 MFS_1 PF07690.16 EWM25620.1 - 6.8e-22 77.9 11.8 1.3e-16 60.4 2.4 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EWM25620.1 - 4.3e-16 58.8 0.7 4.3e-16 58.8 0.7 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter CDC45 PF02724.14 EWM25620.1 - 0.0019 16.6 6.9 0.022 13.1 6.5 2.0 2 0 0 2 2 2 1 CDC45-like protein DUF4536 PF15055.6 EWM25620.1 - 0.0058 16.8 5.5 0.028 14.7 0.2 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4536) Nop14 PF04147.12 EWM25620.1 - 0.012 13.8 17.6 0.018 13.3 17.6 1.2 1 0 0 1 1 1 0 Nop14-like family PI3K_1B_p101 PF10486.9 EWM25620.1 - 0.2 9.4 2.4 0.29 8.9 2.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RXT2_N PF08595.11 EWM25620.1 - 1.3 9.0 6.5 3.9 7.5 6.5 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 EWM25620.1 - 1.6 8.0 16.0 2.9 7.1 16.0 1.3 1 0 0 1 1 1 0 NOA36 protein TFIIA PF03153.13 EWM25620.1 - 2.2 8.2 12.0 3.6 7.5 12.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1840 PF08895.11 EWM25620.1 - 3.2 8.1 6.4 1.4 9.3 1.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Cytomega_UL84 PF06284.11 EWM25620.1 - 4.2 5.7 7.0 6.5 5.1 7.0 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Roughex PF06020.11 EWM25620.1 - 9.7 5.2 8.9 16 4.4 8.9 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Lactamase_B_2 PF12706.7 EWM25621.1 - 2.3e-23 82.8 0.7 4.3e-23 81.9 0.7 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EWM25621.1 - 0.00079 19.5 0.4 0.0016 18.5 0.4 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DAGAT PF03982.13 EWM25622.1 - 2.2e-47 161.4 0.0 3.8e-47 160.6 0.0 1.4 1 1 0 1 1 1 1 Diacylglycerol acyltransferase Patatin PF01734.22 EWM25623.1 - 7e-24 85.1 0.2 2.1e-23 83.6 0.2 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase Glyco_tranf_2_4 PF13704.6 EWM25626.1 - 2e-07 31.4 0.0 4.2e-05 24.0 0.0 2.7 2 0 0 2 2 2 2 Glycosyl transferase family 2 Epimerase PF01370.21 EWM25627.1 - 2.1e-18 66.7 0.0 3e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EWM25627.1 - 3.9e-09 36.7 0.0 1.3e-08 34.9 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EWM25627.1 - 5.7e-07 28.8 0.0 8.9e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EWM25627.1 - 2.1e-05 24.1 0.0 0.00083 18.8 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EWM25627.1 - 2.4e-05 23.7 0.0 0.0001 21.6 0.0 1.8 1 1 1 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 EWM25627.1 - 8.1e-05 21.9 0.5 0.21 10.7 0.0 3.1 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein adh_short PF00106.25 EWM25627.1 - 0.00016 21.2 0.1 1.2 8.6 0.0 3.1 3 0 0 3 3 3 2 short chain dehydrogenase RmlD_sub_bind PF04321.17 EWM25627.1 - 0.0026 16.9 0.0 0.0036 16.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain DFP PF04127.15 EWM25627.1 - 0.0044 16.9 0.1 0.0073 16.1 0.1 1.4 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein NmrA PF05368.13 EWM25627.1 - 0.0075 15.8 0.0 0.017 14.7 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_2 PF03446.15 EWM25627.1 - 0.15 12.3 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase VPS13_C PF16909.5 EWM25628.1 - 3.6e-37 127.9 0.0 3.2e-32 111.7 0.0 2.3 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 EWM25628.1 - 4.5e-20 71.9 0.0 1.2e-19 70.5 0.0 1.7 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13_mid_rpt PF16910.5 EWM25628.1 - 5.2e-20 71.9 0.0 5e-16 58.9 0.0 4.6 4 1 0 4 4 4 1 Repeating coiled region of VPS13 VPS13 PF16908.5 EWM25628.1 - 5.6e-16 59.1 0.0 7.3e-15 55.4 0.0 2.7 2 1 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal ATG_C PF09333.11 EWM25628.1 - 2.3e-10 40.7 0.5 1e-09 38.6 0.1 2.3 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain SHR-BD PF06650.12 EWM25628.1 - 3.5e-08 33.1 0.0 1.2e-07 31.4 0.0 1.8 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 FYVE PF01363.21 EWM25628.1 - 0.00017 21.7 9.3 0.00036 20.6 9.3 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 EWM25628.1 - 0.095 12.9 4.6 0.24 11.6 4.6 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger IBR PF01485.21 EWM25628.1 - 0.71 10.1 3.8 1.5 9.1 3.8 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Siva PF05458.12 EWM25628.1 - 0.99 9.1 7.4 2.1 8.0 7.4 1.4 1 0 0 1 1 1 0 Cd27 binding protein (Siva) Prok-RING_1 PF14446.6 EWM25628.1 - 4.4 7.3 5.9 8.9 6.3 5.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DZR PF12773.7 EWM25628.1 - 9.2 6.4 8.0 22 5.2 8.0 1.6 1 0 0 1 1 1 0 Double zinc ribbon adh_short_C2 PF13561.6 EWM25630.1 - 1.2e-60 205.0 7.8 1.9e-60 204.3 7.8 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EWM25630.1 - 7.8e-58 195.1 6.2 1.2e-57 194.6 6.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EWM25630.1 - 8.6e-20 71.4 6.5 2.4e-19 69.9 3.1 2.2 2 0 0 2 2 2 1 KR domain Gly_kinase PF02595.15 EWM25630.1 - 0.00033 19.8 5.2 0.00046 19.3 0.0 2.8 3 0 0 3 3 3 1 Glycerate kinase family Epimerase PF01370.21 EWM25630.1 - 0.0032 17.0 0.0 0.0093 15.4 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Glyco_hydro_3_C PF01915.22 EWM25630.1 - 0.013 15.4 1.3 0.02 14.8 0.9 1.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain GAD-like PF08887.11 EWM25630.1 - 0.068 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 GAD-like domain DHQ_synthase PF01761.20 EWM25631.1 - 1e-57 195.3 0.0 1.7e-57 194.6 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase Aldo_ket_red PF00248.21 EWM25631.1 - 3e-26 92.3 0.0 6.3e-26 91.2 0.0 1.6 2 0 0 2 2 2 1 Aldo/keto reductase family Fe-ADH_2 PF13685.6 EWM25631.1 - 0.028 14.1 1.0 0.11 12.1 1.0 2.1 1 1 0 1 1 1 0 Iron-containing alcohol dehydrogenase DUF1344 PF07076.11 EWM25631.1 - 0.12 12.3 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) Fe-ADH PF00465.19 EWM25631.1 - 0.25 10.1 0.7 1.7 7.4 0.7 2.2 1 1 0 1 1 1 0 Iron-containing alcohol dehydrogenase FAT PF02259.23 EWM25633.1 - 2.6e-31 109.1 0.0 6.2e-31 107.9 0.0 1.7 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 EWM25633.1 - 3.2e-14 53.3 0.0 7e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Nucleoside_tran PF01733.18 EWM25634.1 - 1.2e-54 185.8 12.3 1.4e-40 139.6 0.3 3.1 3 0 0 3 3 3 3 Nucleoside transporter Nucleoside_tran PF01733.18 EWM25635.1 - 1.4e-54 185.6 12.3 1.6e-40 139.4 0.3 3.2 3 0 0 3 3 3 3 Nucleoside transporter Nucleoside_tran PF01733.18 EWM25636.1 - 1.2e-54 185.8 12.3 1.4e-40 139.6 0.3 3.1 3 0 0 3 3 3 3 Nucleoside transporter Toxin_37 PF11415.8 EWM25637.1 - 0.42 10.5 2.9 1.1 9.2 2.9 1.7 1 0 0 1 1 1 0 Antifungal peptide termicin Toxin_37 PF11415.8 EWM25638.1 - 0.42 10.5 2.9 1.1 9.2 2.9 1.7 1 0 0 1 1 1 0 Antifungal peptide termicin PI3_PI4_kinase PF00454.27 EWM25639.1 - 5.7e-50 170.5 0.0 1e-49 169.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EWM25639.1 - 2.9e-14 52.6 0.0 6.6e-14 51.4 0.0 1.7 1 0 0 1 1 1 1 FATC domain Sec23_trunk PF04811.15 EWM25640.1 - 2.8e-64 217.0 0.0 4.1e-64 216.5 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EWM25640.1 - 9.9e-23 79.9 0.2 1.7e-22 79.2 0.2 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EWM25640.1 - 1.4e-17 64.2 0.0 2.4e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EWM25640.1 - 6.7e-16 58.1 2.6 1.2e-15 57.2 2.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EWM25640.1 - 1.2e-05 25.1 0.0 2.7e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat VWA_2 PF13519.6 EWM25640.1 - 0.054 14.2 0.0 0.21 12.2 0.0 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain VWA PF00092.28 EWM25640.1 - 0.14 12.4 0.0 0.56 10.4 0.0 1.9 2 0 0 2 2 2 0 von Willebrand factor type A domain MRNIP PF15749.5 EWM25640.1 - 0.16 12.7 0.2 0.3 11.8 0.2 1.4 1 0 0 1 1 1 0 MRN-interacting protein Evr1_Alr PF04777.13 EWM25641.1 - 3.5e-23 82.0 0.0 5.9e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 Erv1 / Alr family NeA_P2 PF12312.8 EWM25641.1 - 0.0093 15.4 3.3 0.016 14.7 1.1 2.0 1 1 1 2 2 2 1 Nepovirus subgroup A polyprotein NusG PF02357.19 EWM25642.1 - 6.8e-09 36.1 0.1 2.3e-08 34.4 0.0 1.9 2 0 0 2 2 2 1 Transcription termination factor nusG ThuA PF06283.11 EWM25643.1 - 7.5e-27 94.9 0.0 2.1e-26 93.5 0.0 1.7 2 0 0 2 2 2 1 Trehalose utilisation Epimerase PF01370.21 EWM25643.1 - 1.6e-17 63.8 0.0 3e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ABM PF03992.16 EWM25643.1 - 3.7e-12 46.2 1.1 6.9e-12 45.3 1.1 1.5 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase NAD_binding_10 PF13460.6 EWM25643.1 - 1.3e-07 31.7 0.0 3.3e-07 30.4 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding FMN_red PF03358.15 EWM25643.1 - 1.3e-06 28.2 0.0 3.8e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 NADPH-dependent FMN reductase GDP_Man_Dehyd PF16363.5 EWM25643.1 - 2.4e-06 27.2 0.0 0.0058 16.1 0.0 3.1 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EWM25643.1 - 3e-06 26.4 0.0 4.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EWM25643.1 - 0.001 18.2 0.3 0.86 8.7 0.0 3.0 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein adh_short PF00106.25 EWM25643.1 - 0.0019 17.7 0.1 1.5 8.2 0.0 3.1 3 0 0 3 3 3 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 EWM25643.1 - 0.0098 15.0 0.0 0.019 14.0 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain DFP PF04127.15 EWM25643.1 - 0.017 14.9 0.1 0.033 14.0 0.1 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NmrA PF05368.13 EWM25643.1 - 0.051 13.1 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family Flavodoxin_2 PF02525.17 EWM25643.1 - 0.081 12.6 0.0 0.3 10.7 0.0 1.9 2 0 0 2 2 2 0 Flavodoxin-like fold PT PF04886.12 EWM25644.1 - 0.021 14.3 103.2 2.9 7.5 23.8 5.7 1 1 2 3 3 3 0 PT repeat RRM_1 PF00076.22 EWM25645.1 - 4.8e-18 64.7 0.0 7.1e-18 64.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EWM25645.1 - 6e-06 25.9 0.0 6.9e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sugar_tr PF00083.24 EWM25646.1 - 4.5e-83 279.6 22.8 5.8e-83 279.2 22.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Aldo_ket_red PF00248.21 EWM25646.1 - 9.6e-32 110.3 0.0 2.3e-31 109.1 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.16 EWM25646.1 - 4.7e-22 78.4 49.0 2.5e-18 66.2 22.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pro_isomerase PF00160.21 EWM25647.1 - 1e-48 165.6 0.1 1.4e-48 165.1 0.1 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SAP PF02037.27 EWM25649.1 - 4.1e-11 42.4 0.1 7.5e-11 41.5 0.1 1.5 1 0 0 1 1 1 1 SAP domain CAF1 PF04857.20 EWM25650.1 - 7.5e-19 68.1 0.1 1.8e-09 37.2 0.0 2.6 2 1 0 2 2 2 2 CAF1 family ribonuclease EPTP PF03736.17 EWM25651.1 - 2.6e-09 36.9 0.9 1.9 8.6 0.0 5.3 5 0 0 5 5 5 4 EPTP domain YqjK PF13997.6 EWM25651.1 - 0.044 14.0 1.4 12 6.2 0.2 3.7 2 1 2 4 4 4 0 YqjK-like protein WW PF00397.26 EWM25652.1 - 5.7e-15 55.1 2.2 2.1e-09 37.3 1.9 2.6 2 0 0 2 2 2 2 WW domain MbtH PF03621.13 EWM25652.1 - 0.021 14.3 4.6 0.81 9.2 0.1 3.3 3 0 0 3 3 3 0 MbtH-like protein WW PF00397.26 EWM25653.1 - 3.4e-15 55.8 2.2 1.6e-09 37.7 1.9 2.7 2 0 0 2 2 2 2 WW domain MbtH PF03621.13 EWM25653.1 - 0.015 14.8 4.6 0.63 9.5 0.1 3.1 3 0 0 3 3 3 0 MbtH-like protein LisH PF08513.11 EWM25654.1 - 1.4e-10 40.7 0.0 2.7e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 LisH PAH PF02671.21 EWM25655.1 - 1.4e-19 69.9 2.0 2.3e-19 69.2 2.0 1.4 1 0 0 1 1 1 1 Paired amphipathic helix repeat CHASE3 PF05227.13 EWM25655.1 - 0.00025 21.0 1.6 0.00036 20.5 1.6 1.2 1 0 0 1 1 1 1 CHASE3 domain Cnd1_N PF12922.7 EWM25655.1 - 0.031 14.1 0.2 0.038 13.9 0.2 1.2 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term RPN13_C PF16550.5 EWM25655.1 - 0.06 13.5 0.1 0.079 13.1 0.1 1.2 1 0 0 1 1 1 0 UCH-binding domain HeLo PF14479.6 EWM25655.1 - 0.085 12.7 0.7 0.11 12.4 0.7 1.2 1 0 0 1 1 1 0 Prion-inhibition and propagation TPD52 PF04201.15 EWM25657.1 - 0.13 11.9 0.2 0.16 11.6 0.2 1.1 1 0 0 1 1 1 0 Tumour protein D52 family RINGv PF12906.7 EWM25660.1 - 5.1e-15 55.3 9.1 8.6e-15 54.6 9.1 1.4 1 0 0 1 1 1 1 RING-variant domain zf-ANAPC11 PF12861.7 EWM25660.1 - 0.0008 19.4 2.2 0.0016 18.5 2.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1772 PF08592.11 EWM25660.1 - 0.064 13.6 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) TMEM100 PF16311.5 EWM25660.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 100 DUF1314 PF07013.11 EWM25660.1 - 0.18 11.6 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1314) zf-RING_2 PF13639.6 EWM25660.1 - 0.34 11.3 12.2 0.063 13.6 7.6 2.0 2 0 0 2 2 2 0 Ring finger domain FANCL_C PF11793.8 EWM25660.1 - 0.45 10.7 3.5 0.86 9.8 3.5 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain Lipoxygenase PF00305.19 EWM25661.1 - 1.4e-14 53.5 0.0 3.2e-14 52.3 0.0 1.6 1 1 0 1 1 1 1 Lipoxygenase Methyltransf_16 PF10294.9 EWM25663.1 - 3.7e-05 23.5 0.0 5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Mito_fiss_reg PF05308.11 EWM25663.1 - 0.58 10.2 4.3 0.75 9.8 4.3 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Myb_DNA-binding PF00249.31 EWM25668.1 - 4.1e-12 46.1 0.7 1.6e-11 44.2 0.3 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EWM25668.1 - 0.0019 18.4 0.3 0.0043 17.3 0.3 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EWM25668.1 - 0.0021 17.9 0.2 0.005 16.7 0.2 1.5 1 0 0 1 1 1 1 Myb DNA-binding like DUF4739 PF15893.5 EWM25668.1 - 0.17 11.4 1.1 5.7 6.4 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4739) ER_lumen_recept PF00810.18 EWM25670.1 - 1.9e-35 122.8 6.1 1.9e-35 122.8 6.1 1.9 2 0 0 2 2 2 1 ER lumen protein retaining receptor Fer2 PF00111.27 EWM25673.1 - 1.3e-12 47.5 0.2 2.1e-12 46.8 0.2 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain zf-RING_7 PF02591.15 EWM25673.1 - 0.006 16.7 0.0 2.5 8.4 0.0 2.6 2 0 0 2 2 2 2 C4-type zinc ribbon domain TubC_N PF18563.1 EWM25673.1 - 0.097 12.7 0.0 0.61 10.1 0.0 2.1 1 1 1 2 2 2 0 TubC N-terminal docking domain Inh PF02974.14 EWM25673.1 - 0.13 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Protease inhibitor Inh GCS PF03074.16 EWM25674.1 - 4.6e-08 32.8 0.0 5.4e-08 32.6 0.0 1.0 1 0 0 1 1 1 1 Glutamate-cysteine ligase IBR PF01485.21 EWM25675.1 - 0.095 12.9 0.5 0.095 12.9 0.5 2.4 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain eIF-3c_N PF05470.12 EWM25676.1 - 5.4e-60 203.3 5.6 6.5e-60 203.1 5.6 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 EWM25676.1 - 1.2e-11 45.1 0.0 2.3e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 PCI domain eIF-3c_N PF05470.12 EWM25677.1 - 5.4e-60 203.3 5.6 6.5e-60 203.1 5.6 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 EWM25677.1 - 1.2e-11 45.1 0.0 2.3e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 PCI domain MFS_1 PF07690.16 EWM25678.1 - 7.7e-27 94.1 28.9 7.7e-27 94.1 28.9 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EWM25678.1 - 5.9e-05 22.1 0.3 5.9e-05 22.1 0.3 2.8 3 1 1 4 4 4 1 Sugar (and other) transporter OATP PF03137.20 EWM25678.1 - 0.0014 17.0 0.3 0.0024 16.3 0.3 1.4 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family eIF-3c_N PF05470.12 EWM25680.1 - 2e-13 49.6 0.0 2.1e-13 49.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DNA_pol_phi PF04931.13 EWM25680.1 - 0.032 12.3 0.9 0.035 12.2 0.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi PspA_IM30 PF04012.12 EWM25680.1 - 0.06 12.9 0.9 0.079 12.5 0.9 1.2 1 0 0 1 1 1 0 PspA/IM30 family Cwf_Cwc_15 PF04889.12 EWM25680.1 - 0.08 12.7 6.8 0.11 12.2 6.8 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Env-gp36 PF09590.10 EWM25680.1 - 0.13 10.6 0.0 0.13 10.6 0.0 1.1 1 0 0 1 1 1 0 Lentivirus surface glycoprotein Opi1 PF08618.10 EWM25680.1 - 0.48 9.6 4.2 0.62 9.2 4.2 1.1 1 0 0 1 1 1 0 Transcription factor Opi1 CCDC106 PF15794.5 EWM25680.1 - 3.7 7.2 6.8 5.6 6.6 6.8 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF4692 PF15763.5 EWM25680.1 - 9.1 6.7 8.0 15 6.0 8.0 1.3 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) TORC_M PF12885.7 EWM25681.1 - 4.1 7.3 7.6 8.2 6.3 7.6 1.4 1 0 0 1 1 1 0 Transducer of regulated CREB activity middle domain Pkinase PF00069.25 EWM25682.1 - 0.00022 20.7 0.0 0.32 10.3 0.0 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EWM25682.1 - 0.0027 17.1 0.0 1.5 8.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DUF702 PF05142.12 EWM25683.1 - 0.75 10.3 11.6 0.059 13.8 3.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF702) POP1 PF06978.11 EWM25684.1 - 1.1e-11 45.1 0.5 1.7e-11 44.5 0.5 1.2 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 Sm_multidrug_ex PF06695.11 EWM25686.1 - 1.7e-27 96.5 5.1 4.4e-27 95.1 5.1 1.8 1 0 0 1 1 1 1 Putative small multi-drug export protein NADHdeh_related PF10125.9 EWM25686.1 - 0.055 12.8 1.4 2.8 7.2 0.0 2.2 2 0 0 2 2 2 0 NADH dehydrogenase I, subunit N related protein SNARE_assoc PF09335.11 EWM25686.1 - 0.13 12.7 7.5 0.078 13.5 4.9 2.1 1 1 0 1 1 1 0 SNARE associated Golgi protein Cyclin_N PF00134.23 EWM25689.1 - 7.5e-08 32.2 0.0 1.3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EWM25689.1 - 1.8e-05 25.2 0.1 4.5e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Cyclin NAD_binding_10 PF13460.6 EWM25690.1 - 3.1e-29 102.2 0.1 4.1e-29 101.8 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EWM25690.1 - 2.3e-10 39.9 0.0 3.2e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 EWM25690.1 - 3e-05 23.7 0.0 5.3e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EWM25690.1 - 0.00026 20.5 0.1 0.00061 19.3 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EWM25690.1 - 0.024 13.8 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EWM25690.1 - 0.037 13.1 0.0 0.056 12.5 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain eIF2A PF08662.11 EWM25691.1 - 1.6e-35 122.8 0.1 7.4e-33 114.1 0.0 3.7 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 EWM25691.1 - 1.3e-07 31.8 0.1 0.44 10.9 0.0 5.3 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 EWM25691.1 - 1.5e-05 24.7 0.0 3.6e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Gmad1 PF10647.9 EWM25691.1 - 0.027 14.3 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain RRM_2 PF04059.12 EWM25691.1 - 0.057 13.6 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 RNA recognition motif 2 IKI3 PF04762.12 EWM25691.1 - 0.071 11.1 0.1 0.13 10.3 0.1 1.5 1 0 0 1 1 1 0 IKI3 family COesterase PF00135.28 EWM25691.1 - 0.087 11.7 0.4 0.16 10.8 0.4 1.3 1 0 0 1 1 1 0 Carboxylesterase family Mito_carr PF00153.27 EWM25692.1 - 6.9e-39 131.7 6.2 6.7e-21 74.0 0.1 4.3 3 1 0 3 3 3 3 Mitochondrial carrier protein DnaJ PF00226.31 EWM25696.1 - 2e-16 59.9 0.1 6.3e-16 58.3 0.1 2.0 1 0 0 1 1 1 1 DnaJ domain Myb_DNA-binding PF00249.31 EWM25696.1 - 4.2e-08 33.3 2.8 4.1e-05 23.7 0.4 4.0 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EWM25696.1 - 1.8e-07 31.3 0.4 0.022 15.0 0.4 3.6 2 1 1 3 3 3 2 Myb-like DNA-binding domain V_ATPase_I PF01496.19 EWM25696.1 - 9.4 4.0 5.6 13 3.5 5.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TerC PF03741.16 EWM25697.1 - 2.4e-49 167.5 5.3 4.9e-49 166.5 5.3 1.5 1 0 0 1 1 1 1 Integral membrane protein TerC family AAA_16 PF13191.6 EWM25698.1 - 7e-05 23.3 0.1 0.06 13.7 0.0 3.1 2 1 1 3 3 3 2 AAA ATPase domain AAA PF00004.29 EWM25698.1 - 0.00045 20.6 0.0 0.00076 19.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EWM25698.1 - 0.0015 18.5 0.0 0.0024 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EWM25698.1 - 0.0017 18.0 0.1 0.029 14.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EWM25698.1 - 0.003 17.6 0.0 0.024 14.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EWM25698.1 - 0.0033 17.8 0.0 0.012 16.0 0.0 1.9 1 1 0 1 1 1 1 RNA helicase AAA_2 PF07724.14 EWM25698.1 - 0.0066 16.6 0.0 0.018 15.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) ATPase_2 PF01637.18 EWM25698.1 - 0.011 15.7 0.0 0.13 12.2 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Torsin PF06309.11 EWM25698.1 - 0.012 15.7 0.0 0.024 14.8 0.0 1.6 1 0 0 1 1 1 0 Torsin AAA_22 PF13401.6 EWM25698.1 - 0.021 15.1 0.3 1.4 9.2 0.3 2.4 1 1 0 1 1 1 0 AAA domain ClpB_D2-small PF10431.9 EWM25698.1 - 0.058 13.4 0.1 0.44 10.6 0.0 2.3 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein ResIII PF04851.15 EWM25698.1 - 0.24 11.4 0.0 0.76 9.8 0.0 1.7 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_6 PF12774.7 EWM25698.1 - 0.26 10.2 0.1 0.4 9.6 0.1 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Cation_efflux PF01545.21 EWM25699.1 - 3.3e-26 92.3 9.4 4e-26 92.0 9.4 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EWM25699.1 - 2.2e-10 40.5 0.0 5.2e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter NADH_B2 PF14813.6 EWM25700.1 - 8e-05 22.4 1.9 0.00013 21.7 1.9 1.3 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 5-FTHF_cyc-lig PF01812.20 EWM25700.1 - 0.13 12.1 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 5-formyltetrahydrofolate cyclo-ligase family E1-E2_ATPase PF00122.20 EWM25701.1 - 3e-47 160.5 0.4 1.8e-46 158.0 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EWM25701.1 - 7.1e-46 156.2 0.2 1.9e-45 154.8 0.2 1.8 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EWM25701.1 - 7.3e-21 75.4 1.5 5e-20 72.7 1.2 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EWM25701.1 - 1.2e-18 66.9 0.0 2.3e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EWM25701.1 - 3.4e-15 55.5 0.0 7.7e-15 54.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EWM25701.1 - 4.9e-05 23.2 1.0 0.00037 20.3 0.4 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EWM25701.1 - 0.011 16.1 0.0 0.029 14.8 0.0 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase SPC25 PF06703.11 EWM25703.1 - 5.5e-29 101.1 0.0 6.7e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Cys_Met_Meta_PP PF01053.20 EWM25704.1 - 5e-32 110.9 0.0 6.6e-32 110.5 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EWM25704.1 - 3e-05 23.4 0.0 4.7e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II MAPEG PF01124.18 EWM25706.1 - 2.5e-16 59.8 0.2 3.6e-16 59.2 0.2 1.3 1 0 0 1 1 1 1 MAPEG family AAA_19 PF13245.6 EWM25707.1 - 0.00016 22.1 0.0 0.00043 20.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C PF13361.6 EWM25707.1 - 0.00025 20.5 0.0 0.00045 19.7 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 EWM25707.1 - 0.00075 19.1 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_12 PF13087.6 EWM25707.1 - 0.0034 17.0 0.0 0.0066 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EWM25707.1 - 0.011 15.1 0.3 0.45 9.9 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.6 EWM25707.1 - 0.14 11.8 0.4 0.52 10.0 0.1 1.9 2 0 0 2 2 2 0 AAA domain NAP PF00956.18 EWM25708.1 - 2.6e-60 203.9 0.0 3.6e-60 203.5 0.0 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Pkinase PF00069.25 EWM25711.1 - 2.3e-49 168.1 0.0 3.3e-34 118.5 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EWM25711.1 - 6.8e-29 100.9 0.0 2.4e-27 95.8 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EWM25711.1 - 0.0023 17.3 0.1 0.061 12.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EWM25711.1 - 0.0062 15.4 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Acyltransferase PF01553.21 EWM25712.1 - 4.9e-20 71.5 0.0 7.6e-20 70.9 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 EWM25712.1 - 1.3e-05 25.2 0.0 2.3e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus CMAS PF02353.20 EWM25713.1 - 1.4e-38 132.7 0.2 2.1e-22 79.7 0.0 2.1 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 EWM25713.1 - 2.7e-12 47.2 0.0 4.2e-05 24.1 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 EWM25713.1 - 2.1e-11 44.4 0.0 4.6e-06 27.2 0.0 3.0 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.6 EWM25713.1 - 5.1e-10 39.4 0.0 8.3e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EWM25713.1 - 2.6e-09 37.7 0.0 9.4e-09 35.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM25713.1 - 2.1e-08 34.1 0.0 1.1e-06 28.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EWM25713.1 - 9.7e-07 28.5 0.0 4.9e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 EWM25713.1 - 0.001 18.6 0.0 0.0028 17.1 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase TehB PF03848.14 EWM25713.1 - 0.0035 16.8 0.0 0.0056 16.1 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltr_RsmB-F PF01189.17 EWM25713.1 - 0.0081 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 EWM25713.1 - 0.13 12.4 0.0 0.37 10.9 0.0 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase DREV PF05219.12 EWM25713.1 - 0.18 10.9 0.0 0.53 9.3 0.0 1.7 2 0 0 2 2 2 0 DREV methyltransferase Pkinase PF00069.25 EWM25714.1 - 4.2e-86 288.6 0.0 8.7e-50 169.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EWM25714.1 - 3.4e-75 252.7 0.0 1.8e-61 207.7 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase ANTH PF07651.16 EWM25714.1 - 8.9e-14 51.1 0.0 8.4e-09 34.8 0.0 3.1 3 0 0 3 3 3 2 ANTH domain Kinase-like PF14531.6 EWM25714.1 - 0.00015 21.2 0.0 1.5 8.1 0.0 3.5 4 0 0 4 4 4 2 Kinase-like APH PF01636.23 EWM25714.1 - 0.0066 16.4 7.0 3 7.7 0.1 4.2 3 1 1 4 4 4 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EWM25714.1 - 0.017 13.9 0.0 0.98 8.1 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase Haspin_kinase PF12330.8 EWM25714.1 - 0.13 11.2 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Glycolytic PF00274.19 EWM25715.1 - 2.2e-158 526.5 0.0 2.6e-158 526.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Aldedh PF00171.22 EWM25716.1 - 2.2e-130 435.3 0.0 2.7e-130 435.0 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EWM25716.1 - 0.22 10.5 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Lipocalin_2 PF08212.12 EWM25717.1 - 2.9e-07 30.5 0.0 0.015 15.2 0.0 2.1 2 0 0 2 2 2 2 Lipocalin-like domain EamA PF00892.20 EWM25718.1 - 5.2e-15 55.8 35.0 1.4e-06 28.6 4.2 3.1 3 0 0 3 3 3 3 EamA-like transporter family PUNUT PF16913.5 EWM25718.1 - 0.00034 20.0 1.1 0.00034 20.0 1.1 1.9 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport SLC35F PF06027.12 EWM25718.1 - 0.00093 18.8 0.8 0.00093 18.8 0.8 1.9 2 0 0 2 2 2 1 Solute carrier family 35 TPT PF03151.16 EWM25718.1 - 0.0032 16.9 2.6 0.005 16.2 2.6 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family YesK PF14150.6 EWM25718.1 - 0.19 11.9 6.5 0.57 10.4 1.9 2.8 2 0 0 2 2 2 0 YesK-like protein Rhomboid PF01694.22 EWM25720.1 - 4.6e-28 98.1 8.7 8.2e-28 97.3 8.7 1.4 1 0 0 1 1 1 1 Rhomboid family Pkinase PF00069.25 EWM25722.1 - 5.9e-32 111.1 0.0 8.3e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM25722.1 - 4e-06 26.3 0.0 5.7e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase NUDIX PF00293.28 EWM25723.1 - 4e-11 43.1 0.1 1.2e-10 41.5 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain Nudix_N_2 PF14803.6 EWM25723.1 - 0.0028 17.5 0.1 0.0069 16.3 0.1 1.7 1 0 0 1 1 1 1 Nudix N-terminal SANT_DAMP1_like PF16282.5 EWM25724.1 - 4.1e-23 81.4 0.0 2e-18 66.3 0.0 2.4 2 0 0 2 2 2 2 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 EWM25724.1 - 8.5e-05 22.5 0.4 0.0003 20.7 0.0 2.0 2 0 0 2 2 2 1 DNA methyltransferase 1-associated protein 1 (DMAP1) bZIP_1 PF00170.21 EWM25725.1 - 6.4e-11 42.2 9.3 6.4e-11 42.2 9.3 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 EWM25725.1 - 4.4e-06 26.7 12.0 4.4e-06 26.7 12.0 2.8 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.21 EWM25726.1 - 2.3e-11 43.6 9.3 8.2e-11 41.8 9.3 1.9 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EWM25726.1 - 5.6e-06 26.4 12.0 5.6e-06 26.4 12.0 2.7 3 0 0 3 3 3 1 Basic region leucine zipper Aminotran_4 PF01063.19 EWM25727.1 - 5.8e-23 81.9 0.0 1.3e-17 64.4 0.0 2.1 2 0 0 2 2 2 2 Amino-transferase class IV Aminotran_4 PF01063.19 EWM25728.1 - 5.8e-23 81.9 0.0 1.3e-17 64.4 0.0 2.1 2 0 0 2 2 2 2 Amino-transferase class IV PPTA PF01239.22 EWM25729.1 - 4.4e-12 45.3 7.7 0.00047 19.8 0.1 5.5 5 0 0 5 5 5 4 Protein prenyltransferase alpha subunit repeat DUF3305 PF11749.8 EWM25729.1 - 0.072 13.2 0.4 0.2 11.8 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3305) DSHCT PF08148.12 EWM25730.1 - 2.5e-52 176.9 0.8 2.5e-52 176.9 0.8 1.8 2 0 0 2 2 2 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 EWM25730.1 - 5.7e-52 177.3 0.0 8.7e-52 176.7 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 EWM25730.1 - 5.3e-17 62.1 0.0 4.5e-16 59.1 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EWM25730.1 - 1.5e-08 34.9 0.0 1.6e-07 31.6 0.0 2.5 1 1 0 1 1 1 1 Helicase conserved C-terminal domain GREB1 PF15782.5 EWM25731.1 - 0.94 6.5 7.6 1.1 6.2 7.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RRP14 PF15459.6 EWM25731.1 - 1.1 10.0 4.4 1.8 9.3 4.4 1.4 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 Arrestin_N PF00339.29 EWM25732.1 - 1.7e-18 67.1 0.0 2.1e-16 60.3 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EWM25732.1 - 5.5e-11 43.1 0.0 4.1e-07 30.5 0.0 2.8 2 2 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Drf_FH1 PF06346.12 EWM25732.1 - 1.4 8.6 13.7 0.092 12.5 8.2 1.7 2 0 0 2 2 2 0 Formin Homology Region 1 DnaJ PF00226.31 EWM25733.1 - 3.2e-06 27.2 0.0 5.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DIX PF00778.17 EWM25733.1 - 7.8e-05 22.4 0.0 0.00013 21.7 0.0 1.3 1 0 0 1 1 1 1 DIX domain zf-C3HC4_3 PF13920.6 EWM25735.1 - 6.7e-08 32.3 14.3 1.3e-07 31.3 14.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EWM25735.1 - 8.9e-05 22.3 11.9 0.00029 20.6 11.9 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EWM25735.1 - 0.0025 17.6 13.1 0.0026 17.6 11.9 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EWM25735.1 - 0.031 14.3 13.0 0.065 13.3 13.0 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 EWM25735.1 - 0.095 13.0 15.4 0.15 12.4 14.7 1.7 1 1 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.6 EWM25735.1 - 0.19 11.6 15.8 0.37 10.7 15.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EWM25735.1 - 0.24 11.6 11.6 1 9.5 11.6 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EWM25735.1 - 2.7 8.0 16.4 5.9 6.9 16.4 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_11 PF17123.5 EWM25735.1 - 4.6 7.1 10.7 12 5.7 10.7 1.8 1 0 0 1 1 1 0 RING-like zinc finger PMP22_Claudin PF00822.20 EWM25736.1 - 0.021 14.7 2.5 0.038 13.9 2.3 1.7 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Fer4_19 PF06902.11 EWM25736.1 - 0.11 12.6 0.1 1.8 8.7 0.0 2.2 2 0 0 2 2 2 0 Divergent 4Fe-4S mono-cluster UPF0182 PF03699.13 EWM25736.1 - 0.31 9.1 2.9 0.44 8.6 2.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Amastin PF07344.11 EWM25736.1 - 1.9 8.4 7.7 0.054 13.3 1.5 1.7 2 0 0 2 2 2 0 Amastin surface glycoprotein ABC2_membrane PF01061.24 EWM25738.1 - 3.1e-29 101.9 22.7 3.1e-29 101.9 22.7 2.1 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.27 EWM25738.1 - 1.1e-21 77.8 0.0 1.9e-21 77.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EWM25738.1 - 0.0013 18.7 0.0 0.8 9.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system EGF_2 PF07974.13 EWM25738.1 - 0.0013 19.1 1.9 0.0042 17.4 1.9 1.9 1 0 0 1 1 1 1 EGF-like domain PMT_4TMC PF16192.5 EWM25738.1 - 0.003 17.2 5.8 3.3 7.3 10.3 2.7 1 1 1 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase AAA_29 PF13555.6 EWM25738.1 - 0.0043 16.7 0.1 0.012 15.4 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EWM25738.1 - 0.016 14.6 0.0 2 7.8 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 EWM25738.1 - 0.053 14.1 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EWM25738.1 - 0.072 13.0 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 EWM25738.1 - 0.12 11.9 0.0 0.4 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EWM25738.1 - 0.28 11.7 0.0 0.45 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Laminin_EGF PF00053.24 EWM25738.1 - 1.2 9.3 7.9 0.19 11.9 3.6 1.8 2 0 0 2 2 2 0 Laminin EGF domain His_Phos_2 PF00328.22 EWM25739.1 - 4.5e-06 26.3 0.0 0.0062 15.9 0.0 2.5 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) TruD PF01142.18 EWM25740.1 - 5.8e-35 120.9 0.0 2e-20 73.1 0.0 4.5 5 0 0 5 5 5 4 tRNA pseudouridine synthase D (TruD) FAD_binding_4 PF01565.23 EWM25741.1 - 4.3e-25 88.1 0.4 6.8e-25 87.4 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 EWM25741.1 - 8e-19 68.5 0.0 3.1e-12 46.9 0.0 2.9 2 1 0 2 2 2 2 D-arabinono-1,4-lactone oxidase FAD_binding_5 PF00941.21 EWM25741.1 - 0.18 11.6 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain in molybdopterin dehydrogenase Zeta_toxin PF06414.12 EWM25742.1 - 8.4e-17 61.1 2.1 4.6e-09 35.8 0.0 2.1 2 0 0 2 2 2 2 Zeta toxin EIF_2_alpha PF07541.12 EWM25744.1 - 1.1e-34 119.0 0.0 2.1e-34 118.1 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 EWM25744.1 - 4.7e-11 42.9 0.5 1e-10 41.8 0.5 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Metallophos PF00149.28 EWM25745.1 - 2.1e-19 70.8 0.6 4e-19 69.9 0.6 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 EWM25745.1 - 2.8e-17 63.1 0.0 4.9e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 EWM25745.1 - 5.7e-12 46.3 0.2 1.5e-11 45.0 0.2 1.7 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PUF PF00806.19 EWM25745.1 - 0.032 13.9 0.0 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat Metallophos_2 PF12850.7 EWM25745.1 - 0.11 12.7 0.0 3.2 7.9 0.0 2.3 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain TBCC_N PF16752.5 EWM25746.1 - 5.7e-20 71.9 0.5 9e-20 71.2 0.5 1.3 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain ABC_tran_CTD PF16326.5 EWM25746.1 - 0.012 15.8 0.5 0.026 14.8 0.0 1.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF4028 PF13220.6 EWM25746.1 - 0.029 14.2 0.1 0.051 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4028) SET PF00856.28 EWM25747.1 - 2.4e-08 34.6 0.0 5.7e-08 33.3 0.0 1.8 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 EWM25747.1 - 0.0014 19.3 2.9 0.0028 18.3 2.9 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding GSCFA PF08885.11 EWM25748.1 - 5.7e-43 147.3 0.0 2e-27 96.4 0.0 2.1 2 0 0 2 2 2 2 GSCFA family PGM_PMM_II PF02879.16 EWM25749.1 - 2.4e-19 69.8 0.0 4.7e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_I PF02878.16 EWM25749.1 - 2.3e-14 53.3 0.0 4.8e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EWM25749.1 - 2.2e-12 47.1 0.0 4e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Methyltransf_3 PF01596.17 EWM25750.1 - 5.5e-29 100.9 0.2 2.1e-26 92.4 0.2 3.1 1 1 0 1 1 1 1 O-methyltransferase UPF0176_N PF17773.1 EWM25750.1 - 1.4e-21 76.6 0.0 2.8e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 EWM25750.1 - 5.9e-17 61.8 10.8 1.1e-16 60.9 10.8 1.5 1 0 0 1 1 1 1 Rhodanase C-terminal Methyltransf_24 PF13578.6 EWM25750.1 - 4.4e-10 40.5 0.0 3.3e-09 37.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Rhodanese PF00581.20 EWM25750.1 - 2.3e-07 31.3 0.0 9.2e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain PB1 PF00564.24 EWM25750.1 - 0.026 14.5 0.6 0.14 12.1 0.1 2.3 2 0 0 2 2 2 0 PB1 domain COG4 PF08318.12 EWM25751.1 - 8.6e-38 130.2 0.0 1.3e-37 129.7 0.0 1.3 1 0 0 1 1 1 1 COG4 transport protein RINT1_TIP1 PF04437.13 EWM25751.1 - 0.048 12.6 0.0 0.088 11.7 0.0 1.4 1 0 0 1 1 1 0 RINT-1 / TIP-1 family DUF1664 PF07889.12 EWM25751.1 - 2.3 8.3 3.7 1.5 8.9 0.3 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) EMC3_TMCO1 PF01956.16 EWM25752.1 - 3.7e-34 117.9 0.0 4.8e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like DUF1757 PF08560.10 EWM25753.1 - 3.5e-05 23.9 0.1 8.5e-05 22.7 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1757) Romo1 PF10247.9 EWM25753.1 - 7.7 7.0 11.9 0.33 11.3 1.8 2.7 2 1 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 ELO PF01151.18 EWM25754.1 - 1.2e-55 188.7 29.2 1.2e-55 188.7 29.2 1.3 2 0 0 2 2 2 1 GNS1/SUR4 family ELO PF01151.18 EWM25755.1 - 5e-61 206.4 17.5 6.6e-61 206.0 17.5 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family SNF2_N PF00176.23 EWM25756.1 - 3.6e-53 180.5 0.0 6.2e-53 179.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EWM25756.1 - 8.1e-18 64.8 0.0 1.5e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pyrophosphatase PF00719.19 EWM25757.1 - 1.5e-46 158.1 0.0 2.2e-46 157.6 0.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Dus PF01207.17 EWM25758.1 - 3.4e-53 180.8 0.0 2.2e-52 178.1 0.0 1.9 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) TMP-TENI PF02581.17 EWM25758.1 - 0.04 13.3 0.0 0.066 12.5 0.0 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase PEP_mutase PF13714.6 EWM25758.1 - 0.056 12.9 0.2 0.11 12.0 0.2 1.5 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase His_biosynth PF00977.21 EWM25758.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein NMO PF03060.15 EWM25758.1 - 0.13 11.6 0.1 0.28 10.5 0.1 1.4 1 1 0 1 1 1 0 Nitronate monooxygenase Chloroa_b-bind PF00504.21 EWM25759.1 - 1.8e-39 135.8 0.1 1.6e-24 87.3 0.0 2.3 2 0 0 2 2 2 2 Chlorophyll A-B binding protein Ribosomal_S15 PF00312.22 EWM25760.1 - 8.1e-30 102.9 0.1 1.2e-29 102.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 Ribosomal_L32p PF01783.23 EWM25761.1 - 5.8e-08 32.9 5.9 9.6e-08 32.2 5.9 1.3 1 0 0 1 1 1 1 Ribosomal L32p protein family zf-IS66 PF13005.7 EWM25761.1 - 0.0047 17.3 4.6 1.2 9.6 0.0 2.7 2 1 0 2 2 2 2 zinc-finger binding domain of transposase IS66 zf-ribbon_3 PF13248.6 EWM25761.1 - 0.067 12.6 0.5 0.11 11.9 0.5 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-HIT PF04438.16 EWM25761.1 - 0.46 10.4 5.7 0.53 10.2 2.8 2.1 1 1 1 2 2 2 0 HIT zinc finger RINGv PF12906.7 EWM25762.1 - 0.16 12.1 4.4 0.22 11.7 2.4 2.3 2 1 0 2 2 2 0 RING-variant domain Glyco_hydro_2_C PF02836.17 EWM25763.1 - 1.3e-96 323.3 0.0 1.9e-96 322.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 EWM25763.1 - 1.7e-59 201.4 0.0 2.9e-59 200.6 0.0 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 EWM25763.1 - 3.8e-35 121.3 0.0 8.9e-35 120.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 EWM25763.1 - 9.7e-15 54.8 0.0 1.5e-06 28.6 0.0 2.8 2 0 0 2 2 2 2 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 EWM25763.1 - 8.5e-09 36.1 0.0 2e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_72 PF03198.14 EWM25763.1 - 0.0045 16.3 0.0 0.008 15.5 0.0 1.3 1 0 0 1 1 1 1 Glucanosyltransferase Mito_carr PF00153.27 EWM25764.1 - 2.1e-65 216.7 0.4 5.6e-23 80.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Chloroa_b-bind PF00504.21 EWM25765.1 - 1.1e-33 117.0 0.0 1.6e-33 116.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Tubulin PF00091.25 EWM25766.1 - 2e-37 129.3 0.4 4.3e-37 128.2 0.4 1.6 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 EWM25766.1 - 1.6e-29 102.1 1.7 4.2e-29 100.7 1.7 1.8 1 0 0 1 1 1 1 FtsZ family, C-terminal domain MOZ_SAS PF01853.18 EWM25768.1 - 2.1e-82 275.1 1.0 3e-82 274.6 1.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EWM25768.1 - 9.5e-26 89.2 4.8 9.5e-26 89.2 4.8 1.9 2 0 0 2 2 2 1 MYST family zinc finger domain Tudor-knot PF11717.8 EWM25768.1 - 5.8e-14 51.7 4.3 1.4e-13 50.5 1.5 2.8 2 1 0 2 2 2 1 RNA binding activity-knot of a chromodomain PEARLI-4 PF05278.12 EWM25768.1 - 0.0098 15.5 0.1 0.019 14.6 0.1 1.5 1 0 0 1 1 1 1 Arabidopsis phospholipase-like protein (PEARLI 4) Acetyltransf_7 PF13508.7 EWM25768.1 - 0.025 15.0 0.0 0.25 11.8 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Adap_comp_sub PF00928.21 EWM25769.1 - 4.1e-84 282.1 0.0 5.4e-84 281.7 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EWM25769.1 - 1.3e-06 28.4 0.9 2.2e-06 27.7 0.9 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 EWM25769.1 - 0.00081 18.9 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Longin PF13774.6 EWM25769.1 - 0.0063 16.5 0.3 0.014 15.4 0.3 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Adap_comp_sub PF00928.21 EWM25770.1 - 8.9e-84 281.0 0.0 1.2e-83 280.5 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EWM25770.1 - 1.4e-06 28.3 0.9 2.3e-06 27.6 0.9 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 EWM25770.1 - 0.00087 18.8 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Longin PF13774.6 EWM25770.1 - 0.0066 16.5 0.3 0.015 15.4 0.3 1.6 1 0 0 1 1 1 1 Regulated-SNARE-like domain WD40 PF00400.32 EWM25771.1 - 7.7e-15 55.0 4.4 0.00014 22.6 0.0 5.0 5 1 0 5 5 5 3 WD domain, G-beta repeat RCC1_2 PF13540.6 EWM25771.1 - 1.7 8.5 5.5 0.61 10.0 0.7 2.4 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat PAXIP1_C PF15364.6 EWM25774.1 - 0.15 12.4 5.9 0.23 11.8 5.9 1.3 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein cobW PF02492.19 EWM25776.1 - 2.1e-39 134.9 0.0 4e-39 134.0 0.0 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EWM25776.1 - 3.5e-12 46.1 0.1 8.1e-11 41.7 0.1 2.4 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain AAA_22 PF13401.6 EWM25776.1 - 0.00055 20.2 0.0 0.0029 17.9 0.0 2.2 1 1 1 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EWM25776.1 - 0.0017 18.2 0.0 0.27 11.1 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EWM25776.1 - 0.009 16.4 0.0 0.036 14.5 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain MobB PF03205.14 EWM25776.1 - 0.014 15.3 0.1 0.027 14.4 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 EWM25776.1 - 0.014 15.9 0.0 0.029 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EWM25776.1 - 0.019 14.7 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 EWM25776.1 - 0.024 14.8 0.1 0.046 13.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EWM25776.1 - 0.036 14.6 0.1 0.065 13.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain Sulfotransfer_3 PF13469.6 EWM25776.1 - 0.049 14.0 0.0 0.095 13.1 0.0 1.6 1 0 0 1 1 1 0 Sulfotransferase family ATPase_2 PF01637.18 EWM25776.1 - 0.06 13.3 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 EWM25776.1 - 0.061 13.1 0.1 7.3 6.3 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 EWM25776.1 - 0.07 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 NACHT domain SRPRB PF09439.10 EWM25776.1 - 0.075 12.5 0.1 0.2 11.1 0.1 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 EWM25776.1 - 0.081 12.7 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TrwB_AAD_bind PF10412.9 EWM25776.1 - 0.083 11.8 0.1 0.14 11.0 0.1 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain TsaE PF02367.17 EWM25776.1 - 0.11 12.5 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 EWM25776.1 - 0.13 12.3 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EWM25776.1 - 0.16 11.8 0.3 0.31 10.9 0.3 1.4 1 0 0 1 1 1 0 NTPase MMR_HSR1 PF01926.23 EWM25776.1 - 0.2 11.7 0.7 1.4 9.0 0.7 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase RRM_1 PF00076.22 EWM25778.1 - 0.0029 17.4 0.0 0.0046 16.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4449 PF14613.6 EWM25779.1 - 9.6e-05 22.5 0.3 0.00023 21.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) UNC119_bdg PF15435.6 EWM25779.1 - 0.083 12.4 0.3 15 5.0 0.1 2.4 2 0 0 2 2 2 0 UNC119-binding protein C5orf30 homologue DUF4404 PF14357.6 EWM25779.1 - 7 7.4 9.7 1.4 9.6 2.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) PI3_PI4_kinase PF00454.27 EWM25780.1 - 1.7e-35 123.0 0.0 4.9e-23 82.2 0.0 2.2 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PUMA PF15826.5 EWM25780.1 - 0.0029 17.8 0.2 0.0056 16.9 0.2 1.5 1 0 0 1 1 1 1 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis DUF4135 PF13575.6 EWM25780.1 - 0.0064 15.9 0.0 0.0096 15.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) Sugar_tr PF00083.24 EWM25781.1 - 1.3e-100 337.5 19.7 1.6e-100 337.1 19.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EWM25781.1 - 3.1e-35 121.7 26.3 6.1e-24 84.6 6.7 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EWM25781.1 - 2.4e-05 23.4 0.0 0.086 11.7 0.1 3.1 1 1 2 3 3 3 2 MFS_1 like family OATP PF03137.20 EWM25781.1 - 0.00015 20.2 8.9 0.01 14.1 1.0 2.6 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family GATase_7 PF13537.6 EWM25781.1 - 0.13 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Glutamine amidotransferase domain RSN1_7TM PF02714.15 EWM25782.1 - 3e-45 154.7 9.7 4.4e-45 154.1 9.7 1.2 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EWM25782.1 - 7.1e-27 94.1 5.0 1e-26 93.6 1.7 2.4 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EWM25782.1 - 1.3e-11 45.0 0.0 4e-06 27.2 0.0 2.2 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PPR_2 PF13041.6 EWM25783.1 - 0.00094 19.3 0.0 0.0014 18.8 0.0 1.2 1 0 0 1 1 1 1 PPR repeat family PPR PF01535.20 EWM25783.1 - 0.023 14.9 0.0 0.039 14.2 0.0 1.4 1 0 0 1 1 1 0 PPR repeat TAT_signal PF10518.9 EWM25783.1 - 0.16 11.8 4.3 0.42 10.5 4.3 1.8 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence PPR_2 PF13041.6 EWM25784.1 - 0.00094 19.3 0.0 0.0014 18.8 0.0 1.2 1 0 0 1 1 1 1 PPR repeat family PPR PF01535.20 EWM25784.1 - 0.023 14.9 0.0 0.039 14.2 0.0 1.4 1 0 0 1 1 1 0 PPR repeat TAT_signal PF10518.9 EWM25784.1 - 0.16 11.8 4.3 0.42 10.5 4.3 1.8 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence PPR_2 PF13041.6 EWM25785.1 - 0.00094 19.3 0.0 0.0014 18.8 0.0 1.2 1 0 0 1 1 1 1 PPR repeat family PPR PF01535.20 EWM25785.1 - 0.023 14.9 0.0 0.039 14.2 0.0 1.4 1 0 0 1 1 1 0 PPR repeat TAT_signal PF10518.9 EWM25785.1 - 0.16 11.8 4.3 0.42 10.5 4.3 1.8 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Sfi1_C PF10638.9 EWM25786.1 - 0.024 15.4 0.1 0.075 13.8 0.0 1.9 2 0 0 2 2 2 0 Spindle body associated protein C-terminus TPX2_importin PF12214.8 EWM25787.1 - 1.2e-16 61.3 14.5 1.6e-09 38.2 2.0 5.1 2 1 2 4 4 4 3 Cell cycle regulated microtubule associated protein ArfGap PF01412.18 EWM25788.1 - 3.8e-32 110.8 0.0 8.5e-32 109.7 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf MR_MLE_N PF02746.16 EWM25788.1 - 0.19 12.0 0.8 0.39 10.9 0.8 1.5 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain FXMRP1_C_core PF12235.8 EWM25788.1 - 0.58 10.8 5.1 0.37 11.4 2.7 1.9 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal STAG PF08514.11 EWM25790.1 - 5.4e-12 45.6 0.0 1.5e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 STAG domain Cnd1 PF12717.7 EWM25790.1 - 0.00076 19.6 0.0 0.14 12.2 0.0 2.5 1 1 2 3 3 3 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EWM25790.1 - 0.028 13.0 0.0 0.054 12.0 0.0 1.3 1 0 0 1 1 1 0 Adaptin N terminal region UPF0020 PF01170.18 EWM25792.1 - 1.1e-35 123.1 0.0 5.5e-33 114.3 0.0 2.7 2 1 0 2 2 2 2 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 EWM25792.1 - 9.7e-17 61.5 0.1 6.1e-14 52.5 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 EWM25792.1 - 3.6e-16 59.4 0.0 1.9e-14 53.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM25792.1 - 1e-14 54.9 0.0 5e-14 52.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EWM25792.1 - 5.1e-10 39.1 0.0 1.1e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EWM25792.1 - 8.1e-10 38.7 0.0 1.8e-07 31.0 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 EWM25792.1 - 2e-06 28.5 0.0 4.8e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EWM25792.1 - 0.066 12.6 0.0 0.46 9.8 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) NIF PF03031.18 EWM25794.1 - 2.2e-55 186.7 0.0 3.2e-55 186.2 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Dus PF01207.17 EWM25795.1 - 2.4e-56 191.1 0.0 3.1e-56 190.8 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 EWM25795.1 - 0.01 15.3 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein Med2 PF11214.8 EWM25796.1 - 0.17 12.1 0.1 10 6.3 0.0 2.4 2 0 0 2 2 2 0 Mediator complex subunit 2 Fcf2 PF08698.11 EWM25797.1 - 7.7e-20 71.1 0.3 2.4e-19 69.5 0.1 2.0 1 1 0 1 1 1 1 Fcf2 pre-rRNA processing RAWUL PF16207.5 EWM25798.1 - 0.00017 22.2 0.0 0.00031 21.3 0.0 1.5 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_2 PF13923.6 EWM25798.1 - 0.0002 21.2 6.6 0.00026 20.8 5.6 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF3337 PF11816.8 EWM25798.1 - 0.053 13.4 0.0 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3337) zf-C3HC4 PF00097.25 EWM25798.1 - 0.83 9.6 9.4 1.9 8.5 9.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EWM25798.1 - 4 7.7 8.8 9.8 6.4 8.8 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING mTERF PF02536.14 EWM25799.1 - 1.9e-30 105.9 0.0 3e-26 92.1 0.0 4.7 2 1 0 2 2 2 2 mTERF AMP-binding PF00501.28 EWM25800.1 - 8.1e-71 238.8 0.0 1e-70 238.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EWM25800.1 - 4e-12 46.9 0.3 1.2e-11 45.4 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Peroxin-3 PF04882.12 EWM25801.1 - 2.2e-27 96.2 0.0 1.5e-25 90.2 0.0 2.1 1 1 1 2 2 2 2 Peroxin-3 DUF1930 PF09122.10 EWM25802.1 - 0.033 14.2 0.0 0.058 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1930) MerT PF02411.15 EWM25802.1 - 0.035 14.1 0.2 0.07 13.2 0.2 1.5 1 0 0 1 1 1 0 MerT mercuric transport protein HMA PF00403.26 EWM25802.1 - 0.098 13.1 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Heavy-metal-associated domain RELT PF12606.8 EWM25802.1 - 0.3 10.1 4.8 0.31 10.1 0.1 2.4 2 0 0 2 2 2 0 Tumour necrosis factor receptor superfamily member 19 Glyco_hydro_8 PF01270.17 EWM25803.1 - 3.2e-28 98.5 8.4 4.7e-28 98.0 8.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 8 MazG PF03819.17 EWM25804.1 - 1.1e-05 25.5 0.0 2.6e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain MazG-like PF12643.7 EWM25804.1 - 0.04 14.2 0.1 0.33 11.2 0.0 2.3 2 0 0 2 2 2 0 MazG-like family Cnd1 PF12717.7 EWM25805.1 - 0.00011 22.3 0.0 0.02 14.9 0.0 3.4 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EWM25805.1 - 0.00058 19.9 4.7 1.9 9.0 0.1 5.7 6 0 0 6 6 6 2 HEAT repeat RIX1 PF08167.12 EWM25805.1 - 0.0024 17.7 1.1 0.026 14.2 0.1 3.3 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis RTP1_C1 PF10363.9 EWM25805.1 - 0.019 15.2 0.2 11 6.3 0.0 4.3 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF3954 PF13128.6 EWM25805.1 - 0.058 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3954) Bromodomain PF00439.25 EWM25806.1 - 1.4e-18 66.7 0.0 1.1e-14 54.2 0.0 2.6 2 0 0 2 2 2 2 Bromodomain PHD PF00628.29 EWM25806.1 - 2.1e-09 37.1 28.4 5.7e-08 32.5 10.9 2.8 2 0 0 2 2 2 2 PHD-finger WSD PF15613.6 EWM25806.1 - 1.1e-08 35.5 1.7 3.5e-08 33.8 0.0 2.9 2 0 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif PHD_2 PF13831.6 EWM25806.1 - 0.73 9.4 18.1 0.028 14.0 1.8 3.5 2 1 0 2 2 2 0 PHD-finger BING4CT PF08149.11 EWM25807.1 - 8.7e-38 128.0 0.0 2.2e-34 117.1 0.0 2.8 2 0 0 2 2 2 2 BING4CT (NUC141) domain WD40 PF00400.32 EWM25807.1 - 3.1e-09 37.3 0.3 0.00015 22.5 0.0 5.3 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM25807.1 - 7.8e-08 32.5 0.0 1.3 9.4 0.0 5.0 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EWM25807.1 - 0.0079 14.8 1.0 2.5 6.5 0.0 2.8 3 0 0 3 3 3 2 Cytochrome D1 heme domain Mur_ligase_M PF08245.12 EWM25809.1 - 2.2e-05 24.5 0.0 0.021 14.8 0.0 3.0 2 1 0 2 2 2 2 Mur ligase middle domain Mur_ligase_C PF02875.21 EWM25809.1 - 0.0046 17.2 0.0 0.01 16.1 0.0 1.6 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain DUF4112 PF13430.6 EWM25810.1 - 0.047 14.0 0.0 0.08 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4112) Radical_SAM PF04055.21 EWM25811.1 - 5.9e-10 39.8 0.0 9.7e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 EWM25811.1 - 2e-05 24.7 0.0 3.8e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 EWM25811.1 - 0.067 13.5 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S single cluster domain BRCT_2 PF16589.5 EWM25812.1 - 2.2e-08 34.4 0.0 0.077 13.4 0.0 3.9 3 1 0 3 3 3 3 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EWM25812.1 - 5.5e-07 29.9 0.0 0.05 14.0 0.0 2.8 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 EWM25812.1 - 0.00021 21.1 0.0 0.0085 16.0 0.0 2.9 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain zf-RanBP PF00641.18 EWM25812.1 - 0.002 17.4 2.9 0.0051 16.1 2.9 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others LIG3_BRCT PF16759.5 EWM25812.1 - 0.03 14.6 0.0 3.3 8.1 0.0 3.3 3 0 0 3 3 3 0 DNA ligase 3 BRCT domain zf-C2H2_11 PF16622.5 EWM25813.1 - 0.48 10.2 3.5 0.83 9.5 3.5 1.4 1 0 0 1 1 1 0 zinc-finger C2H2-type RTC PF01137.21 EWM25814.1 - 7.6e-57 192.1 0.0 8.7e-57 191.9 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 EWM25814.1 - 1.5e-33 115.4 0.0 3e-33 114.4 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Tubulin PF00091.25 EWM25815.1 - 2e-63 214.2 0.0 3.2e-63 213.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EWM25815.1 - 3.8e-51 172.5 0.1 5.6e-51 172.0 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EWM25815.1 - 0.0065 16.2 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Utp12 PF04003.12 EWM25816.1 - 2e-21 76.3 0.5 3.9e-21 75.4 0.2 1.6 2 0 0 2 2 2 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 EWM25816.1 - 2.2e-07 31.1 0.0 0.058 13.7 0.0 4.0 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EWM25816.1 - 1.1e-05 26.1 2.7 0.015 16.2 0.0 4.9 5 0 0 5 5 5 1 WD domain, G-beta repeat eIF2A PF08662.11 EWM25816.1 - 0.14 12.0 0.0 0.43 10.4 0.0 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A zf-RING_2 PF13639.6 EWM25817.1 - 7e-05 23.1 8.4 0.00018 21.8 8.4 1.8 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 EWM25817.1 - 0.0048 16.9 1.7 0.014 15.4 1.7 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger C1_1 PF00130.22 EWM25817.1 - 0.0051 16.7 1.2 0.0051 16.7 1.2 1.8 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4 PF00097.25 EWM25817.1 - 0.019 14.8 8.8 0.044 13.6 8.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EWM25817.1 - 0.023 14.8 4.6 0.074 13.2 4.6 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain HEAT PF02985.22 EWM25817.1 - 0.031 14.5 0.0 0.36 11.2 0.0 3.0 2 0 0 2 2 2 0 HEAT repeat zf-rbx1 PF12678.7 EWM25817.1 - 0.046 14.0 5.5 0.13 12.6 5.5 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING-like PF08746.11 EWM25817.1 - 0.22 11.9 4.3 0.59 10.5 4.3 1.7 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 EWM25817.1 - 0.42 10.8 13.0 0.072 13.2 8.7 2.1 2 0 0 2 2 2 0 RING-variant domain zf-C3HC4_2 PF13923.6 EWM25817.1 - 1.1 9.2 7.2 2.6 7.9 7.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EWM25817.1 - 2.2 8.0 4.2 8.2 6.1 4.2 2.0 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 EWM25817.1 - 9.3 6.2 6.5 24 4.9 6.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.32 EWM25818.1 - 4.9e-15 55.7 7.5 0.00089 20.0 0.2 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM25818.1 - 0.00019 21.6 0.0 36 4.7 0.0 4.6 2 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EWM25818.1 - 0.00041 20.7 0.2 0.9 10.1 0.0 3.9 4 1 0 4 4 4 1 PQQ-like domain Marek_SORF3 PF07153.11 EWM25818.1 - 0.061 12.6 0.0 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 Marek's disease-like virus SORF3 protein WD40 PF00400.32 EWM25820.1 - 2.9e-08 34.2 7.2 0.5 11.3 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM25820.1 - 0.0025 18.1 0.0 5.6 7.3 0.0 3.6 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Cyt-b5 PF00173.28 EWM25821.1 - 3.1e-19 68.9 0.0 5.3e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PAPS_reduct PF01507.19 EWM25822.1 - 7.3e-37 127.1 0.0 1e-36 126.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family vMSA PF00695.19 EWM25822.1 - 0.0065 15.6 0.0 0.0091 15.1 0.0 1.1 1 0 0 1 1 1 1 Major surface antigen from hepadnavirus PRP38 PF03371.15 EWM25823.1 - 1.7e-59 200.6 0.2 2.2e-59 200.2 0.2 1.1 1 0 0 1 1 1 1 PRP38 family TauD PF02668.16 EWM25825.1 - 3.1e-53 181.3 0.1 4.5e-53 180.8 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family COG4 PF08318.12 EWM25826.1 - 9.9e-10 38.0 0.1 8.3e-08 31.7 0.0 3.0 3 1 0 3 3 3 2 COG4 transport protein Filaggrin PF03516.13 EWM25826.1 - 0.07 13.9 1.3 0.21 12.3 1.3 1.8 1 0 0 1 1 1 0 Filaggrin COG4 PF08318.12 EWM25827.1 - 7.3e-10 38.4 0.0 5.4e-08 32.3 0.0 2.8 2 1 0 2 2 2 2 COG4 transport protein Filaggrin PF03516.13 EWM25827.1 - 2.7 8.8 7.0 0.16 12.7 1.3 2.0 2 0 0 2 2 2 0 Filaggrin UCR_TM PF02921.14 EWM25828.1 - 3.3e-12 46.7 0.1 6.5e-12 45.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 EWM25828.1 - 1.8e-10 40.6 0.0 3.2e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DUF4286 PF14114.6 EWM25829.1 - 3.1e-15 56.4 0.1 6.1e-15 55.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4286) HRCT1 PF15758.5 EWM25829.1 - 0.095 13.7 0.1 0.35 11.9 0.1 1.9 1 0 0 1 1 1 0 Histidine-rich carboxyl terminus protein 1 DUF4286 PF14114.6 EWM25830.1 - 3.1e-15 56.4 0.1 6.1e-15 55.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4286) HRCT1 PF15758.5 EWM25830.1 - 0.095 13.7 0.1 0.35 11.9 0.1 1.9 1 0 0 1 1 1 0 Histidine-rich carboxyl terminus protein 1 tRNA-synt_2b PF00587.25 EWM25831.1 - 4.5e-32 111.5 0.0 8.4e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EWM25831.1 - 1.3e-16 60.7 5.1 2.1e-16 60.1 5.1 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF615 PF04751.14 EWM25831.1 - 0.053 13.5 5.3 0.032 14.2 2.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF615) DUF3584 PF12128.8 EWM25831.1 - 0.11 10.0 5.1 0.15 9.5 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) APG6_N PF17675.1 EWM25831.1 - 1.8 9.1 9.3 5.5 7.5 9.3 1.8 1 0 0 1 1 1 0 Apg6 coiled-coil region UQ_con PF00179.26 EWM25832.1 - 5.2e-48 162.2 0.1 5.9e-48 162.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EWM25832.1 - 0.00038 20.2 0.0 0.00049 19.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EWM25832.1 - 0.055 13.3 0.1 0.096 12.6 0.1 1.4 1 1 0 1 1 1 0 UEV domain ABC_tran PF00005.27 EWM25833.1 - 5.2e-47 159.8 1.0 1.5e-24 87.1 0.0 3.2 4 0 0 4 4 3 2 ABC transporter ABC_tran_Xtn PF12848.7 EWM25833.1 - 1.9e-21 75.9 2.1 1.9e-21 75.9 2.1 3.8 4 0 0 4 4 4 1 ABC transporter AAA_21 PF13304.6 EWM25833.1 - 1.5e-20 74.2 2.8 0.0002 21.3 0.1 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EWM25833.1 - 4.6e-14 52.4 0.3 3.8e-07 29.8 0.0 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_tran_CTD PF16326.5 EWM25833.1 - 1.2e-07 31.9 5.8 1.2e-07 31.9 5.8 3.3 4 0 0 4 4 3 1 ABC transporter C-terminal domain AAA_29 PF13555.6 EWM25833.1 - 2.1e-07 30.6 1.3 0.011 15.4 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EWM25833.1 - 1e-05 26.2 13.8 0.0067 17.0 0.0 3.6 4 0 0 4 4 3 2 AAA domain AAA_30 PF13604.6 EWM25833.1 - 1.9e-05 24.5 1.3 0.05 13.3 0.1 3.0 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EWM25833.1 - 5.4e-05 23.5 7.3 0.037 14.3 0.1 3.5 4 0 0 4 4 3 2 AAA domain RsgA_GTPase PF03193.16 EWM25833.1 - 0.00014 21.8 2.8 0.051 13.5 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase AAA_16 PF13191.6 EWM25833.1 - 0.00017 22.0 5.7 0.01 16.2 0.1 3.1 2 1 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.23 EWM25833.1 - 0.00021 21.4 2.4 0.38 10.8 0.0 3.5 4 0 0 4 4 3 1 Dynamin family MMR_HSR1 PF01926.23 EWM25833.1 - 0.00025 21.1 1.2 0.92 9.6 0.1 2.9 3 0 0 3 3 2 2 50S ribosome-binding GTPase MeaB PF03308.16 EWM25833.1 - 0.00035 19.6 3.5 0.092 11.7 0.3 2.8 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 EWM25833.1 - 0.00045 20.5 1.1 0.14 12.4 0.1 3.2 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.6 EWM25833.1 - 0.00071 20.1 0.0 0.23 12.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 EWM25833.1 - 0.001 18.8 0.1 1.2 8.8 0.1 2.6 2 1 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_19 PF13245.6 EWM25833.1 - 0.0018 18.6 1.8 1.8 8.9 0.1 2.8 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EWM25833.1 - 0.0024 17.5 0.2 0.67 9.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 EWM25833.1 - 0.0046 16.9 0.2 0.047 13.6 0.1 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain AAA PF00004.29 EWM25833.1 - 0.007 16.8 0.3 0.19 12.2 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EWM25833.1 - 0.0088 15.8 0.5 1.4 8.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EWM25833.1 - 0.012 15.1 0.5 0.66 9.5 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_15 PF13175.6 EWM25833.1 - 0.015 15.1 8.1 0.062 13.0 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain Mg_chelatase PF01078.21 EWM25833.1 - 0.016 14.6 0.8 0.13 11.6 0.0 2.5 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI SbcCD_C PF13558.6 EWM25833.1 - 0.024 14.9 4.1 2.2 8.6 0.1 4.1 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 EWM25833.1 - 0.03 14.7 0.2 1.1 9.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Arf PF00025.21 EWM25833.1 - 0.049 13.1 0.5 4.5 6.7 0.0 2.6 3 0 0 3 3 2 0 ADP-ribosylation factor family MukB PF04310.12 EWM25833.1 - 0.061 13.1 2.9 3.5 7.4 0.0 3.2 3 0 0 3 3 3 0 MukB N-terminal AAA_14 PF13173.6 EWM25833.1 - 0.064 13.3 0.0 5.3 7.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 EWM25833.1 - 0.065 12.4 0.0 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit DAP3 PF10236.9 EWM25833.1 - 0.11 11.7 1.3 1.8 7.6 0.1 2.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_17 PF13207.6 EWM25833.1 - 0.2 12.1 4.2 14 6.1 0.1 3.4 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 EWM25833.1 - 0.25 11.3 2.6 1.2 9.1 0.1 3.1 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 EWM25833.1 - 0.28 11.1 3.2 2.5 8.0 0.1 2.9 3 0 0 3 3 3 0 NACHT domain AAA_27 PF13514.6 EWM25833.1 - 0.34 10.5 0.0 0.34 10.5 0.0 3.9 4 1 1 5 5 5 0 AAA domain AAA_33 PF13671.6 EWM25833.1 - 0.47 10.6 7.6 2.2 8.5 0.1 4.2 5 0 0 5 5 5 0 AAA domain PRK PF00485.18 EWM25833.1 - 0.51 10.0 1.6 38 3.9 0.0 3.1 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family IstB_IS21 PF01695.17 EWM25833.1 - 0.98 9.1 5.5 12 5.6 0.0 3.5 5 0 0 5 5 3 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 EWM25833.1 - 1.4 8.1 6.6 3.3 7.0 0.1 3.0 3 0 0 3 3 2 0 Zeta toxin 2OG-FeII_Oxy_3 PF13640.6 EWM25834.1 - 2e-13 51.0 0.0 5.5e-13 49.6 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EWM25834.1 - 0.0077 16.7 0.1 0.71 10.4 0.0 3.5 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Trypsin_2 PF13365.6 EWM25835.1 - 1e-19 71.9 0.2 4e-18 66.8 0.0 3.0 3 1 1 4 4 4 1 Trypsin-like peptidase domain PDZ_1 PF12812.7 EWM25835.1 - 8.2e-14 51.4 0.0 1.4e-05 25.0 0.0 2.6 2 0 0 2 2 2 2 PDZ-like domain PDZ_6 PF17820.1 EWM25835.1 - 1.1e-11 44.4 0.0 4.6e-05 23.2 0.0 4.5 4 0 0 4 4 4 2 PDZ domain PDZ_2 PF13180.6 EWM25835.1 - 8.8e-10 38.8 0.0 2.4e-05 24.6 0.0 4.4 4 1 0 4 4 4 1 PDZ domain PDZ PF00595.24 EWM25835.1 - 3.6e-07 30.4 0.0 0.28 11.6 0.0 4.3 4 0 0 4 4 4 2 PDZ domain Tricorn_PDZ PF14685.6 EWM25835.1 - 0.00057 19.8 0.0 0.23 11.5 0.0 3.4 3 0 0 3 3 3 1 Tricorn protease PDZ domain Peptidase_S7 PF00949.21 EWM25835.1 - 0.053 13.3 0.3 0.12 12.2 0.3 1.6 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease FemAB_like PF04339.12 EWM25836.1 - 1.6e-118 396.1 0.0 1.9e-118 395.8 0.0 1.0 1 0 0 1 1 1 1 Peptidogalycan biosysnthesis/recognition Acetyltransf_6 PF13480.7 EWM25836.1 - 5e-08 33.2 0.0 1e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Fe-ADH PF00465.19 EWM25837.1 - 6.5e-47 160.1 0.0 1.3e-46 159.1 0.0 1.4 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase CMD PF02627.20 EWM25837.1 - 0.0001 22.3 0.0 0.0002 21.3 0.0 1.6 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Fe-ADH_2 PF13685.6 EWM25837.1 - 0.038 13.7 0.7 0.25 11.0 0.2 2.2 1 1 1 2 2 2 0 Iron-containing alcohol dehydrogenase PFK PF00365.20 EWM25837.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Phosphofructokinase DUF3703 PF12487.8 EWM25837.1 - 0.21 11.4 0.9 0.59 10.0 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3703) Misat_Tub_SegII PF10644.9 EWM25838.1 - 1.5e-14 54.3 0.0 2.4e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 EWM25838.1 - 0.013 15.7 0.0 0.15 12.2 0.0 2.0 2 0 0 2 2 2 0 Tubulin/FtsZ family, GTPase domain BRO1 PF03097.18 EWM25840.1 - 1.1e-90 304.2 0.9 1.1e-90 304.2 0.9 1.6 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EWM25840.1 - 1.9e-35 122.6 10.2 1.9e-35 122.6 10.2 2.3 3 0 0 3 3 3 1 ALIX V-shaped domain binding to HIV UBA PF00627.31 EWM25840.1 - 0.0029 17.5 0.1 0.0088 15.9 0.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.6 EWM25840.1 - 0.037 13.8 0.9 0.16 11.8 0.1 2.2 2 0 0 2 2 2 0 UBA-like domain CUE PF02845.16 EWM25840.1 - 0.11 12.3 0.2 4.8 7.0 0.0 2.9 3 0 0 3 3 3 0 CUE domain HOIP-UBA PF16678.5 EWM25840.1 - 0.26 11.3 4.4 0.44 10.6 0.2 3.0 3 0 0 3 3 3 0 HOIP UBA domain pair CCDC50_N PF15295.6 EWM25840.1 - 3.7 7.7 13.2 3.6 7.8 5.4 3.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 50 N-terminus TACC_C PF05010.14 EWM25840.1 - 6.5 6.5 12.4 0.15 11.9 0.7 3.0 3 0 0 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal RRM_1 PF00076.22 EWM25841.1 - 7.8e-39 131.3 0.0 4e-19 68.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EWM25841.1 - 0.00015 21.8 0.1 0.12 12.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif OB_RNB PF08206.11 EWM25841.1 - 0.00018 21.1 0.4 0.013 15.2 0.1 2.4 2 0 0 2 2 2 1 Ribonuclease B OB domain Limkain-b1 PF11608.8 EWM25841.1 - 0.034 14.2 0.0 0.71 10.0 0.0 2.3 2 0 0 2 2 2 0 Limkain b1 RRM_5 PF13893.6 EWM25841.1 - 0.044 13.4 0.0 0.59 9.7 0.0 2.1 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UPF0047 PF01894.17 EWM25842.1 - 6.9e-32 110.0 0.0 7.7e-32 109.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 AAA_2 PF07724.14 EWM25843.1 - 2.3e-40 138.5 0.0 1e-32 113.6 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 EWM25843.1 - 4.8e-14 52.9 0.1 4.6e-06 27.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EWM25843.1 - 1.1e-07 31.8 0.6 3.1e-07 30.4 0.6 1.8 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 EWM25843.1 - 8.6e-07 29.0 0.0 0.00018 21.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EWM25843.1 - 1.5e-05 25.3 0.2 0.001 19.4 0.0 3.3 4 0 0 4 4 4 1 AAA domain MCM PF00493.23 EWM25843.1 - 4.3e-05 22.7 0.0 0.0014 17.7 0.0 2.2 2 0 0 2 2 2 1 MCM P-loop domain AAA_16 PF13191.6 EWM25843.1 - 6.3e-05 23.4 0.3 0.0016 18.8 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 EWM25843.1 - 7.4e-05 22.9 0.0 0.00016 21.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EWM25843.1 - 0.00048 19.6 0.1 0.0068 15.8 0.0 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 EWM25843.1 - 0.00064 19.5 0.1 0.034 13.9 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EWM25843.1 - 0.0016 17.7 0.0 0.0037 16.5 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain Zeta_toxin PF06414.12 EWM25843.1 - 0.0022 17.3 0.0 0.0052 16.1 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin ATP-synt_ab PF00006.25 EWM25843.1 - 0.0024 17.5 0.0 0.005 16.5 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activat PF00158.26 EWM25843.1 - 0.0033 17.2 0.0 0.03 14.0 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain G-alpha PF00503.20 EWM25843.1 - 0.011 14.9 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_18 PF13238.6 EWM25843.1 - 0.03 14.8 0.0 0.088 13.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 EWM25843.1 - 0.044 14.0 0.2 0.2 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EWM25843.1 - 0.047 14.2 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 EWM25843.1 - 0.055 13.2 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.15 EWM25843.1 - 0.062 13.2 0.0 0.34 10.8 0.0 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_14 PF13173.6 EWM25843.1 - 0.077 13.0 0.1 7.1 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain CPT PF07931.12 EWM25843.1 - 0.08 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein TniB PF05621.11 EWM25843.1 - 0.096 12.1 0.1 0.27 10.6 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein NACHT PF05729.12 EWM25843.1 - 0.12 12.2 0.0 2.1 8.2 0.0 2.6 2 1 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 EWM25843.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 EWM25843.1 - 0.13 12.3 0.0 0.52 10.3 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 EWM25843.1 - 0.16 12.3 1.2 0.58 10.5 0.1 2.4 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EWM25843.1 - 0.33 10.8 1.5 0.82 9.5 0.1 2.2 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea DUF726 PF05277.12 EWM25844.1 - 1.8e-87 293.5 6.4 2.6e-37 128.6 0.1 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF726) DUF900 PF05990.12 EWM25844.1 - 0.086 12.3 0.0 0.22 11.0 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_6 PF12697.7 EWM25844.1 - 0.09 13.4 0.1 0.53 10.9 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF3730 PF12530.8 EWM25845.1 - 2.1e-11 43.8 1.9 4.2e-11 42.9 0.3 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3730) Methyltransf_31 PF13847.6 EWM25846.1 - 3.7e-30 104.7 0.0 6.1e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM25846.1 - 3e-18 66.3 0.1 6.2e-18 65.3 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM25846.1 - 4.5e-18 65.7 0.1 9.2e-18 64.7 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EWM25846.1 - 4.4e-13 49.1 0.0 6.7e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EWM25846.1 - 2.9e-10 40.8 0.0 6.5e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EWM25846.1 - 1.8e-09 37.7 0.0 2.7e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EWM25846.1 - 5.9e-06 26.2 0.1 1.2e-05 25.2 0.1 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.15 EWM25846.1 - 1.2e-05 25.3 0.1 3.6e-05 23.7 0.1 1.8 1 1 0 2 2 2 1 Hypothetical methyltransferase PrmA PF06325.13 EWM25846.1 - 0.00012 21.6 0.0 0.00031 20.2 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) YhcG_C PF06250.11 EWM25846.1 - 0.066 13.0 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 YhcG PDDEXK nuclease domain GCD14 PF08704.10 EWM25846.1 - 0.099 12.3 0.1 0.2 11.3 0.1 1.5 1 1 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit FtsJ PF01728.19 EWM25846.1 - 0.11 12.6 0.1 0.23 11.6 0.1 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase HECT PF00632.25 EWM25847.1 - 1.8e-81 274.0 0.0 2.4e-81 273.6 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) NRBF2_MIT PF17169.4 EWM25849.1 - 0.072 13.3 3.2 0.26 11.5 3.2 2.0 1 0 0 1 1 1 0 MIT domain of nuclear receptor-binding factor 2 Glyco_hydro_63 PF03200.16 EWM25850.1 - 8.9e-147 489.8 0.0 1.1e-84 285.0 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 EWM25850.1 - 5.6e-35 121.5 0.0 1.2e-33 117.1 0.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain GDE_C PF06202.14 EWM25850.1 - 0.0061 15.5 0.1 0.011 14.7 0.1 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Trehalase PF01204.18 EWM25850.1 - 0.12 11.2 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Trehalase ACT_6 PF13740.6 EWM25851.1 - 6.3e-11 42.1 0.0 1.3e-09 37.9 0.0 2.3 2 0 0 2 2 2 1 ACT domain ACT PF01842.25 EWM25851.1 - 4.2e-06 26.4 0.0 0.016 15.0 0.0 2.4 2 0 0 2 2 2 2 ACT domain ACT_4 PF13291.6 EWM25851.1 - 0.0025 18.3 0.0 1.5 9.4 0.0 2.4 2 0 0 2 2 2 2 ACT domain Ribophorin_I PF04597.14 EWM25852.1 - 4.8e-104 349.0 0.0 5.8e-104 348.7 0.0 1.1 1 0 0 1 1 1 1 Ribophorin I cwf18 PF08315.12 EWM25853.1 - 6.1e-20 72.3 7.2 3.2e-16 60.2 7.4 2.2 1 1 1 2 2 2 2 cwf18 pre-mRNA splicing factor SIR4_SID PF16991.5 EWM25853.1 - 0.09 12.8 0.4 0.14 12.2 0.4 1.4 1 0 0 1 1 1 0 Sir4 SID domain RPN2_C PF18004.1 EWM25854.1 - 2e-41 141.6 0.3 3.2e-41 140.9 0.3 1.3 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 EWM25854.1 - 7.6e-29 98.7 27.0 5.8e-07 29.6 0.1 8.4 8 0 0 8 8 8 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EWM25854.1 - 2.7e-18 66.2 11.5 9.9e-13 48.3 0.1 4.8 3 1 0 4 4 4 3 HEAT repeats HEAT PF02985.22 EWM25854.1 - 0.0012 18.9 2.7 14 6.3 0.1 5.1 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 EWM25854.1 - 0.012 15.7 0.7 1.8 8.6 0.0 3.3 3 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EWM25854.1 - 1 10.0 9.4 6.6 7.3 0.1 5.4 4 2 3 7 7 7 0 HEAT-like repeat WD40 PF00400.32 EWM25855.1 - 3.7e-19 68.7 19.6 2e-06 28.4 0.2 7.1 7 1 0 7 7 7 4 WD domain, G-beta repeat ATG16 PF08614.11 EWM25855.1 - 4.8e-17 62.8 20.2 4.8e-17 62.8 20.2 1.5 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) ANAPC4_WD40 PF12894.7 EWM25855.1 - 3.6e-05 24.0 0.0 1.2 9.5 0.0 4.9 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain CENP-H PF05837.12 EWM25855.1 - 0.00018 21.9 8.7 0.00018 21.9 8.7 3.1 2 2 1 3 3 3 1 Centromere protein H (CENP-H) DUF4407 PF14362.6 EWM25855.1 - 0.0053 16.1 9.8 0.0053 16.1 9.8 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4407) Spc7 PF08317.11 EWM25855.1 - 0.4 9.5 25.3 1.7 7.4 9.0 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein FapA PF03961.13 EWM25855.1 - 1.5 7.3 12.0 0.051 12.2 3.5 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A Spc42p PF11544.8 EWM25855.1 - 2.1 8.4 11.3 2.2 8.3 0.6 4.2 4 1 0 5 5 5 0 Spindle pole body component Spc42p ING PF12998.7 EWM25855.1 - 2.5 8.8 10.0 1.9 9.1 2.1 2.5 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF2807 PF10988.8 EWM25855.1 - 8.3 6.2 5.8 4 7.2 0.8 3.1 2 1 0 2 2 2 0 Putative auto-transporter adhesin, head GIN domain Semialdhyde_dh PF01118.24 EWM25857.1 - 9.4e-27 93.9 0.0 1.5e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 EWM25857.1 - 1.8e-18 67.3 0.0 2.6e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain S1 PF00575.23 EWM25858.1 - 0.15 12.4 0.6 11 6.4 0.0 2.7 3 0 0 3 3 3 0 S1 RNA binding domain UBA PF00627.31 EWM25859.1 - 3.9e-17 61.8 8.1 2.3e-09 36.9 2.2 2.7 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 EWM25859.1 - 9.7e-17 60.5 6.4 9.7e-17 60.5 6.4 2.6 3 0 0 3 3 3 1 XPC-binding domain ubiquitin PF00240.23 EWM25859.1 - 2.1e-13 49.8 0.1 4.1e-13 48.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EWM25859.1 - 1.8e-07 30.9 0.3 4.4e-07 29.6 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 EWM25859.1 - 0.00037 20.2 0.1 2.4 8.1 0.0 3.3 3 0 0 3 3 3 2 Fungal ubiquitin-associated domain DUF2407 PF10302.9 EWM25859.1 - 0.23 12.1 0.0 0.48 11.0 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF3135 PF11333.8 EWM25859.1 - 0.31 11.3 4.2 0.45 10.8 0.0 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF3135) Thioredoxin PF00085.20 EWM25860.1 - 2e-08 34.1 0.1 4.1e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 EWM25860.1 - 3.2e-06 26.3 0.6 4e-06 26.0 0.6 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin_2 PF13098.6 EWM25860.1 - 0.36 11.3 1.8 0.48 10.9 0.4 1.9 2 1 0 2 2 2 0 Thioredoxin-like domain AGTRAP PF06396.11 EWM25861.1 - 0.018 14.8 0.3 0.024 14.4 0.3 1.2 1 0 0 1 1 1 0 Angiotensin II, type I receptor-associated protein (AGTRAP) DUF3523 PF12037.8 EWM25862.1 - 4.8e-77 258.9 36.4 7.5e-77 258.3 36.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.29 EWM25862.1 - 6.8e-22 78.3 0.0 1.4e-21 77.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EWM25862.1 - 0.00052 20.0 2.6 0.11 12.5 0.1 3.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EWM25862.1 - 0.0012 19.0 2.0 0.0021 18.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 EWM25862.1 - 0.0024 17.6 0.0 0.0068 16.2 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 EWM25862.1 - 0.0031 16.9 0.2 0.017 14.5 0.1 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 EWM25862.1 - 0.0041 17.5 0.1 0.0041 17.5 0.1 3.5 2 2 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 EWM25862.1 - 0.0047 17.2 8.3 0.18 12.1 0.0 3.7 4 1 0 4 4 3 2 AAA domain Zot PF05707.12 EWM25862.1 - 0.011 15.4 0.2 0.21 11.2 0.0 2.7 1 1 0 2 2 2 0 Zonular occludens toxin (Zot) ATPase PF06745.13 EWM25862.1 - 0.011 15.1 2.3 0.21 10.9 0.0 2.4 2 0 0 2 2 2 0 KaiC TsaE PF02367.17 EWM25862.1 - 0.012 15.6 0.1 0.04 13.9 0.1 1.9 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 EWM25862.1 - 0.019 15.1 0.0 0.1 12.7 0.0 2.2 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_11 PF13086.6 EWM25862.1 - 0.1 12.3 0.0 0.1 12.3 0.0 3.5 2 2 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 EWM25862.1 - 0.18 12.2 0.0 0.42 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Arm-DNA-bind_3 PF13356.6 EWM25862.1 - 5.4 7.5 6.8 0.64 10.4 0.4 2.8 2 0 0 2 2 2 0 Arm DNA-binding domain Cyclin_N PF00134.23 EWM25863.1 - 5e-49 165.3 1.4 1e-44 151.4 0.1 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 EWM25863.1 - 2.8e-30 104.8 0.8 5.4e-30 103.9 0.8 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain WD40 PF00400.32 EWM25864.1 - 0.013 16.3 0.5 0.22 12.4 0.1 3.3 4 0 0 4 4 4 0 WD domain, G-beta repeat Peptidase_M16 PF00675.20 EWM25865.1 - 2e-25 89.5 0.1 4.2e-25 88.5 0.1 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EWM25865.1 - 4.2e-17 62.7 0.0 7.4e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain CHASE8 PF17152.4 EWM25865.1 - 0.0038 17.4 1.5 0.011 16.0 1.5 1.8 1 0 0 1 1 1 1 Periplasmic sensor domain Fer4_13 PF13370.6 EWM25866.1 - 3.9e-17 62.5 2.4 1.3e-16 60.8 2.4 1.9 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 EWM25866.1 - 2e-08 34.8 2.4 2e-08 34.8 2.4 3.0 3 1 0 3 3 3 1 4Fe-4S single cluster domain Fer4_21 PF14697.6 EWM25866.1 - 0.0023 18.0 1.9 0.0023 18.0 1.9 2.1 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_19 PF06902.11 EWM25866.1 - 0.052 13.6 0.6 0.15 12.2 0.6 1.8 1 0 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Fer4_10 PF13237.6 EWM25866.1 - 0.066 13.3 9.0 20 5.4 1.2 2.6 1 1 1 2 2 2 0 4Fe-4S dicluster domain ANAPC_CDC26 PF10471.9 EWM25866.1 - 0.077 13.8 6.9 0.18 12.6 0.2 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Fer4_9 PF13187.6 EWM25866.1 - 0.33 11.2 7.8 0.13 12.4 1.7 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 EWM25866.1 - 0.72 10.5 9.8 45 4.7 10.1 2.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain TMA7 PF09072.10 EWM25866.1 - 1.8 9.5 5.0 1.9 9.4 0.2 2.4 2 0 0 2 2 2 0 Translation machinery associated TMA7 Fer4_2 PF12797.7 EWM25866.1 - 4.2 7.7 11.4 0.26 11.5 0.7 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Adaptin_N PF01602.20 EWM25868.1 - 1.8e-127 426.1 1.4 2.2e-127 425.8 1.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 EWM25868.1 - 4.1e-23 81.8 0.0 7.6e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 EWM25868.1 - 2.9e-14 53.5 4.1 7.9e-08 32.5 0.4 2.4 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EWM25868.1 - 1.7e-06 27.8 1.3 0.13 12.6 0.1 5.9 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.6 EWM25868.1 - 2.6e-06 27.7 6.8 0.12 12.8 0.0 4.9 4 1 0 4 4 4 2 HEAT repeats Dopey_N PF04118.14 EWM25868.1 - 0.0025 17.0 0.3 0.0064 15.6 0.2 1.7 2 0 0 2 2 2 1 Dopey, N-terminal CLASP_N PF12348.8 EWM25868.1 - 0.0056 16.3 0.2 2.4 7.6 0.0 2.5 2 0 0 2 2 2 2 CLASP N terminal DUF5578 PF17741.1 EWM25868.1 - 0.015 14.7 1.5 1.3 8.4 0.1 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5578) Exo70 PF03081.15 EWM25868.1 - 0.026 13.6 0.3 0.75 8.8 0.0 2.2 1 1 1 2 2 2 0 Exo70 exocyst complex subunit Vac14_Fab1_bd PF12755.7 EWM25868.1 - 0.038 14.6 0.4 12 6.6 0.0 3.3 2 2 1 3 3 3 0 Vacuolar 14 Fab1-binding region UNC45-central PF11701.8 EWM25868.1 - 0.1 12.6 0.1 0.37 10.7 0.1 2.0 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central RTP1_C1 PF10363.9 EWM25868.1 - 0.18 12.0 0.5 2 8.6 0.1 2.8 2 2 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 RasGEF_N_2 PF14663.6 EWM25868.1 - 6.2 7.3 5.2 19 5.7 0.0 3.8 5 1 1 6 6 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Glyco_hydro_9 PF00759.19 EWM25871.1 - 5.9e-120 401.4 6.0 6.9e-120 401.2 6.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 BID PF06393.11 EWM25872.1 - 0.012 15.2 1.3 0.017 14.7 1.3 1.3 1 0 0 1 1 1 0 BH3 interacting domain (BID) BclA_C PF18573.1 EWM25872.1 - 0.023 14.6 0.2 0.042 13.8 0.2 1.3 1 0 0 1 1 1 0 BclA C-terminal domain Nup54 PF13874.6 EWM25872.1 - 0.025 14.7 2.0 0.04 14.0 2.0 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF1043 PF06295.12 EWM25872.1 - 0.04 13.9 1.1 0.063 13.3 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) GAS PF13851.6 EWM25872.1 - 0.38 10.1 5.5 0.56 9.5 5.5 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Mito_carr PF00153.27 EWM25873.1 - 3.2e-56 187.2 5.1 2.3e-25 88.3 0.0 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 EWM25873.1 - 0.00022 20.5 0.2 0.074 12.2 0.0 2.2 2 0 0 2 2 2 2 Gammaproteobacterial serine protease ubiquitin PF00240.23 EWM25874.1 - 4.6e-08 32.7 0.2 1.2e-07 31.3 0.2 1.6 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 EWM25874.1 - 8.2e-05 23.0 0.1 0.00038 20.8 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 EWM25874.1 - 0.014 15.2 0.2 0.049 13.5 0.2 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 EWM25874.1 - 0.042 13.9 0.2 0.22 11.6 0.1 1.8 1 1 1 2 2 2 0 Ubiquitin-like domain Frataxin_Cyay PF01491.16 EWM25875.1 - 3.6e-06 27.0 0.0 5e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain DEAD PF00270.29 EWM25876.1 - 4.4e-48 163.4 0.0 7.4e-48 162.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EWM25876.1 - 5.2e-32 110.5 0.0 2.1e-31 108.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EWM25876.1 - 0.0011 19.0 0.0 0.0018 18.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 EWM25876.1 - 0.09 11.5 0.0 0.46 9.2 0.0 2.0 2 1 1 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Adaptin_N PF01602.20 EWM25877.1 - 2.5e-147 491.6 10.4 3e-147 491.4 10.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EWM25877.1 - 3e-64 215.9 4.3 3e-63 212.7 0.1 2.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 EWM25877.1 - 7.7e-18 64.6 0.0 2e-17 63.3 0.0 1.8 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 EWM25877.1 - 2.8e-17 62.9 11.5 2.2e-06 27.9 0.4 5.7 2 2 4 6 6 6 5 HEAT repeats HEAT PF02985.22 EWM25877.1 - 4.7e-09 35.7 7.6 0.031 14.5 0.1 5.9 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.6 EWM25877.1 - 3.8e-06 27.3 8.0 0.69 10.5 0.3 5.5 5 1 1 6 6 6 2 HEAT-like repeat Arm PF00514.23 EWM25877.1 - 0.00012 22.0 2.9 0.43 10.7 0.0 4.6 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Cnd3 PF12719.7 EWM25877.1 - 0.00013 21.3 0.7 0.077 12.2 0.1 3.0 3 1 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 EWM25877.1 - 0.00017 21.7 1.3 3.7 7.8 0.0 4.2 1 1 2 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Alpha_adaptinC2 PF02883.20 EWM25877.1 - 0.00039 20.7 0.0 0.001 19.4 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain CLASP_N PF12348.8 EWM25877.1 - 0.0041 16.7 0.3 2.3 7.7 0.0 2.9 2 1 0 2 2 2 2 CLASP N terminal Sec7_N PF12783.7 EWM25877.1 - 0.013 15.4 1.8 0.1 12.5 0.1 2.7 1 1 1 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal UNC45-central PF11701.8 EWM25877.1 - 0.048 13.6 0.1 1.7 8.6 0.0 2.8 2 1 0 2 2 2 0 Myosin-binding striated muscle assembly central DUF5578 PF17741.1 EWM25877.1 - 0.16 11.4 2.2 3.6 6.9 0.1 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5578) HEAT_PBS PF03130.16 EWM25877.1 - 0.71 10.7 3.4 39 5.3 0.2 4.4 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat DUF4282 PF14110.6 EWM25878.1 - 0.003 18.2 14.8 0.0043 17.8 14.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4282) Bac_rhamnosid_N PF08531.10 EWM25879.1 - 0.016 15.0 1.1 5.7 6.7 0.1 3.1 3 0 0 3 3 3 0 Alpha-L-rhamnosidase N-terminal domain Ank_2 PF12796.7 EWM25880.1 - 2e-08 34.7 0.0 8.5e-08 32.7 0.0 2.1 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EWM25880.1 - 1.7e-06 28.4 0.1 0.0039 17.7 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EWM25880.1 - 3.4e-05 24.1 0.3 0.001 19.3 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EWM25880.1 - 0.0044 17.4 0.0 0.15 12.7 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 EWM25880.1 - 0.015 15.7 0.0 4.7 7.8 0.0 3.3 4 0 0 4 4 4 0 Ankyrin repeat Metallophos PF00149.28 EWM25881.1 - 1.7e-07 31.9 0.2 2.5e-07 31.4 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5305 PF17231.2 EWM25881.1 - 0.15 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Metallophos PF00149.28 EWM25882.1 - 2.5e-19 70.6 0.9 3.4e-19 70.2 0.9 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PhoD PF09423.10 EWM25882.1 - 0.049 12.6 0.0 1.8 7.5 0.0 2.2 2 0 0 2 2 2 0 PhoD-like phosphatase Cupin_7 PF12973.7 EWM25883.1 - 0.00089 19.1 0.0 0.4 10.6 0.0 2.3 2 0 0 2 2 2 2 ChrR Cupin-like domain GNAT_acetyltr_2 PF13718.6 EWM25885.1 - 8.6e-90 300.1 0.0 2.2e-89 298.7 0.0 1.7 2 0 0 2 2 2 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.14 EWM25885.1 - 3.2e-60 203.0 0.0 6.1e-60 202.1 0.0 1.5 1 0 0 1 1 1 1 Helicase tRNA_bind_2 PF13725.6 EWM25885.1 - 1.3e-45 156.0 0.0 3.2e-45 154.7 0.0 1.6 1 1 0 1 1 1 1 Possible tRNA binding domain DUF1726 PF08351.11 EWM25885.1 - 5.7e-33 112.7 0.1 1.7e-32 111.2 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 EWM25885.1 - 0.0085 15.8 0.3 3.8 7.2 0.0 3.3 3 1 0 3 3 3 1 AAA domain Acetyltransf_1 PF00583.25 EWM25885.1 - 0.05 13.8 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family AAA_22 PF13401.6 EWM25885.1 - 0.11 12.8 0.2 19 5.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain DinB_2 PF12867.7 EWM25885.1 - 0.26 11.8 1.5 1.4 9.5 0.0 2.7 3 0 0 3 3 3 0 DinB superfamily G6PD_C PF02781.16 EWM25886.1 - 1.7e-103 345.8 0.0 2.4e-103 345.3 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 EWM25886.1 - 6.5e-56 189.8 0.0 8.8e-56 189.3 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain MPS2 PF17060.5 EWM25887.1 - 0.16 11.2 10.8 0.26 10.5 10.5 1.4 1 1 0 1 1 1 0 Monopolar spindle protein 2 HALZ PF02183.18 EWM25887.1 - 0.18 12.0 3.3 1.9 8.8 0.3 3.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF1664 PF07889.12 EWM25887.1 - 0.73 9.9 4.1 1.1 9.4 2.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TPR_14 PF13428.6 EWM25890.1 - 1.1e-07 32.1 23.3 0.00075 20.1 2.7 7.4 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 EWM25890.1 - 1.6e-07 31.7 3.8 0.016 15.7 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EWM25890.1 - 8.5e-07 29.5 16.1 0.0057 17.3 1.5 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EWM25890.1 - 0.002 18.1 2.5 0.077 13.2 0.4 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat Stk19 PF10494.9 EWM25891.1 - 4.1e-19 69.2 0.4 3e-17 63.1 0.4 2.9 1 1 0 1 1 1 1 Serine-threonine protein kinase 19 CREPT PF16566.5 EWM25892.1 - 0.013 15.7 1.9 0.013 15.7 1.9 3.7 2 1 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour V_ATPase_I PF01496.19 EWM25892.1 - 2.7 5.8 7.1 5.9 4.7 7.1 1.6 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sec6 PF06046.13 EWM25893.1 - 1.7e-12 46.5 0.0 6.7e-05 21.5 0.0 2.9 2 1 0 2 2 2 2 Exocyst complex component Sec6 ADIP PF11559.8 EWM25893.1 - 0.016 15.3 2.6 0.04 14.0 2.6 1.7 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Elf1 PF05129.13 EWM25893.1 - 0.19 11.8 0.2 0.38 10.8 0.2 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like SRP-alpha_N PF04086.13 EWM25893.1 - 4.7 7.0 4.9 13 5.6 4.9 1.7 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RCC1 PF00415.18 EWM25894.1 - 2.7e-36 123.9 42.4 1.3e-10 41.7 0.8 8.3 7 3 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EWM25894.1 - 2.1e-28 97.5 43.7 5.2e-08 32.5 0.7 8.4 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat ChaC PF04752.12 EWM25894.1 - 1.2e-23 84.1 0.0 2.1e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 ChaC-like protein GGACT PF06094.12 EWM25894.1 - 0.00016 22.3 0.1 0.00058 20.4 0.0 1.9 2 0 0 2 2 2 1 Gamma-glutamyl cyclotransferase, AIG2-like PapC_C PF13953.6 EWM25894.1 - 0.039 13.8 0.4 0.67 9.8 0.0 3.1 3 0 0 3 3 3 0 PapC C-terminal domain Reg_prop PF07494.11 EWM25894.1 - 0.43 11.0 3.5 2.9 8.4 0.2 3.4 3 0 0 3 3 3 0 Two component regulator propeller DUF4213 PF13938.6 EWM25894.1 - 2 8.7 7.5 4.7 7.5 0.1 3.7 4 0 0 4 4 4 0 Putative heavy-metal chelation UQ_con PF00179.26 EWM25895.1 - 2.7e-17 62.7 0.0 3.2e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EWM25895.1 - 0.056 13.7 0.0 0.074 13.3 0.0 1.4 1 1 0 1 1 1 0 RWD domain Zip PF02535.22 EWM25896.1 - 3.1e-56 191.0 5.6 4.6e-56 190.5 5.6 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter SBP_bac_11 PF13531.6 EWM25896.1 - 0.0046 16.7 0.6 0.0065 16.2 0.6 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein DUF4212 PF13937.6 EWM25896.1 - 0.0053 17.1 0.6 0.0053 17.1 0.6 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4212) CreA PF05981.12 EWM25897.1 - 8.3e-41 139.0 0.2 1.4e-40 138.3 0.2 1.3 1 0 0 1 1 1 1 CreA protein DUF2358 PF10184.9 EWM25897.1 - 1.5e-13 51.0 0.0 3.7e-13 49.8 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2358) DUF4185 PF13810.6 EWM25898.1 - 0.00065 19.0 1.2 0.0019 17.5 0.4 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4185) SLC3A2_N PF16028.5 EWM25898.1 - 0.11 12.1 0.0 0.39 10.3 0.0 1.9 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus Aldedh PF00171.22 EWM25899.1 - 8.1e-175 581.8 0.0 9.3e-175 581.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EWM25899.1 - 0.05 13.1 0.2 0.2 11.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) MFS_1 PF07690.16 EWM25900.1 - 3.2e-22 78.9 14.4 4.8e-13 48.7 4.8 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Aconitase PF00330.20 EWM25901.1 - 1.4e-78 265.0 0.0 3.7e-53 181.2 0.0 2.0 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) GSK-3_bind PF05350.12 EWM25901.1 - 0.096 12.0 1.0 0.41 9.9 1.4 1.8 2 0 0 2 2 2 0 Glycogen synthase kinase-3 binding PrsW-protease PF13367.6 EWM25903.1 - 7.2e-10 38.6 7.2 7.2e-10 38.6 7.2 2.1 1 1 1 2 2 2 1 PrsW family intramembrane metalloprotease E1_DerP2_DerF2 PF02221.15 EWM25905.1 - 1.1e-11 45.3 0.1 1.3e-11 45.0 0.1 1.1 1 0 0 1 1 1 1 ML domain MoaC PF01967.21 EWM25905.1 - 0.027 14.6 0.0 0.085 13.0 0.0 1.7 1 1 1 2 2 2 0 MoaC family RRM_1 PF00076.22 EWM25906.1 - 1.7e-08 34.2 0.0 2.1e-06 27.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peripla_BP_2 PF01497.18 EWM25907.1 - 9.3e-26 90.8 0.0 1.3e-25 90.4 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein Pyrophosphatase PF00719.19 EWM25908.1 - 1.1e-47 161.9 0.0 1.3e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Aldo_ket_red PF00248.21 EWM25910.1 - 1.7e-21 76.7 0.0 2.2e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family DUF308 PF03729.13 EWM25911.1 - 0.012 15.9 0.3 0.012 15.9 0.3 3.4 2 1 1 3 3 3 0 Short repeat of unknown function (DUF308) HupE_UreJ_2 PF13795.6 EWM25911.1 - 0.013 15.2 3.2 0.077 12.6 0.2 2.4 2 1 0 2 2 2 0 HupE / UreJ protein HupE_UreJ PF04955.12 EWM25911.1 - 1.6 8.2 12.9 0.069 12.6 2.1 3.0 3 1 0 3 3 3 0 HupE / UreJ protein Sulfate_transp PF00916.20 EWM25912.1 - 1.7e-87 293.7 16.2 2.1e-87 293.4 16.2 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EWM25912.1 - 1.2e-13 50.7 0.0 6.7e-13 48.3 0.0 2.2 2 1 0 2 2 2 1 STAS domain STAS_2 PF13466.6 EWM25912.1 - 0.0012 19.2 0.6 0.025 14.9 0.0 2.7 2 0 0 2 2 2 1 STAS domain MFS_MOT1 PF16983.5 EWM25912.1 - 3.9 7.9 15.5 0.062 13.7 5.2 3.3 2 2 1 3 3 3 0 Molybdate transporter of MFS superfamily DnaJ PF00226.31 EWM25913.1 - 4e-24 84.5 0.1 8.6e-24 83.5 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain SPATA24 PF15175.6 EWM25913.1 - 0.019 14.9 1.4 0.034 14.0 1.4 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 Grg1 PF11034.8 EWM25913.1 - 0.054 13.7 0.2 0.16 12.2 0.2 1.8 1 0 0 1 1 1 0 Glucose-repressible protein Grg1 RAP1 PF07218.11 EWM25914.1 - 7.2 4.8 11.3 7.8 4.6 11.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) VKOR PF07884.14 EWM25915.1 - 3.4e-28 98.3 4.0 3.4e-28 98.3 4.0 1.6 2 0 0 2 2 2 1 Vitamin K epoxide reductase family Peptidase_M16_M PF16187.5 EWM25916.1 - 8.8e-64 215.5 0.0 1.2e-63 215.0 0.0 1.2 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 EWM25916.1 - 3.5e-37 127.7 0.0 3.6e-36 124.4 0.0 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EWM25916.1 - 2.5e-17 63.5 0.0 4.7e-09 36.5 0.0 5.1 4 2 1 5 5 5 3 Peptidase M16 inactive domain zf-RING_11 PF17123.5 EWM25916.1 - 0.24 11.2 1.4 26 4.7 0.1 2.9 2 0 0 2 2 2 0 RING-like zinc finger CS PF04969.16 EWM25917.1 - 1.7e-16 61.0 0.0 4.1e-07 30.9 0.0 2.4 2 0 0 2 2 2 2 CS domain PHD PF00628.29 EWM25918.1 - 4.3e-25 87.4 84.8 4.5e-09 36.1 8.6 8.4 6 1 2 8 8 8 5 PHD-finger SET PF00856.28 EWM25918.1 - 1.8e-19 70.8 0.2 1.8e-19 70.8 0.2 3.7 3 1 0 3 3 3 1 SET domain Bromodomain PF00439.25 EWM25918.1 - 1.7e-16 60.0 0.0 3.5e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Bromodomain FYRN PF05964.14 EWM25918.1 - 1e-15 57.3 0.0 1.9e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus zf-HC5HC2H PF13771.6 EWM25918.1 - 5.5e-10 39.4 9.8 5.5e-10 39.4 9.8 8.4 6 2 2 8 8 8 2 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EWM25918.1 - 1.6e-08 34.6 9.1 1.6e-08 34.6 9.1 6.8 5 2 1 6 6 6 2 PHD-zinc-finger like domain PWWP PF00855.17 EWM25918.1 - 1.2e-05 25.6 0.1 1.2e-05 25.6 0.1 3.4 4 0 0 4 4 4 1 PWWP domain FYRC PF05965.14 EWM25918.1 - 0.00016 21.8 0.0 0.19 11.9 0.0 2.8 2 0 0 2 2 2 2 F/Y rich C-terminus Luteo_Vpg PF01659.16 EWM25918.1 - 0.0096 16.2 1.2 0.037 14.4 1.2 2.0 1 0 0 1 1 1 1 Luteovirus putative VPg genome linked protein Epimerase PF01370.21 EWM25919.1 - 1.1e-53 182.2 0.0 2e-53 181.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.6 EWM25919.1 - 5.6e-25 88.1 0.0 1.2e-24 87.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain GDP_Man_Dehyd PF16363.5 EWM25919.1 - 3.3e-18 66.2 0.7 1.6e-17 63.9 0.7 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Methyltransf_11 PF08241.12 EWM25919.1 - 9.2e-15 55.1 0.0 1.9e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM25919.1 - 3.9e-13 49.9 0.0 9.5e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EWM25919.1 - 5.5e-13 48.8 0.0 1.2e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EWM25919.1 - 4.2e-08 33.8 0.0 1e-07 32.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.15 EWM25919.1 - 1.2e-07 31.2 0.5 1.6e-05 24.2 0.0 3.0 2 1 1 3 3 3 1 Polysaccharide biosynthesis protein Methyltransf_31 PF13847.6 EWM25919.1 - 8e-07 29.0 0.0 1.7e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RmlD_sub_bind PF04321.17 EWM25919.1 - 2.3e-05 23.7 0.0 7.1e-05 22.0 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 EWM25919.1 - 0.00083 18.4 0.1 0.0022 17.1 0.1 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NodS PF05401.11 EWM25919.1 - 0.042 13.5 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) SlyX PF04102.12 EWM25920.1 - 0.0019 18.8 2.5 0.0044 17.6 2.5 1.6 1 0 0 1 1 1 1 SlyX DASH_Spc19 PF08287.11 EWM25920.1 - 0.023 14.6 0.2 0.037 13.9 0.2 1.2 1 0 0 1 1 1 0 Spc19 CCDC53 PF10152.9 EWM25920.1 - 0.048 14.1 0.1 0.08 13.4 0.1 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex P4Ha_N PF08336.11 EWM25920.1 - 0.17 11.9 0.1 0.24 11.4 0.1 1.2 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region F5_F8_type_C PF00754.25 EWM25921.1 - 0.013 15.6 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 F5/8 type C domain ANAPC10 PF03256.16 EWM25921.1 - 0.17 11.5 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) PC-Esterase PF13839.6 EWM25922.1 - 1.6e-07 31.4 0.0 7.6e-05 22.6 0.0 2.5 2 1 0 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Fer4_16 PF13484.6 EWM25923.1 - 1.3e-20 74.1 6.0 2.3e-20 73.3 6.0 1.4 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain DUF1730 PF08331.10 EWM25923.1 - 5.5e-16 58.3 0.0 1.5e-15 56.8 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1730) Fer4_7 PF12838.7 EWM25923.1 - 2e-06 28.3 5.7 6.4e-06 26.7 5.9 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 EWM25923.1 - 4.7e-05 23.5 3.5 0.015 15.4 0.9 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EWM25923.1 - 0.00012 22.1 7.8 0.0085 16.2 1.9 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 EWM25923.1 - 0.00056 19.6 13.2 0.0042 16.9 3.0 2.7 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_18 PF13746.6 EWM25923.1 - 0.0089 16.2 3.0 0.045 13.9 0.3 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 EWM25923.1 - 0.015 15.3 4.4 0.015 15.3 4.4 2.5 2 1 0 2 2 2 0 4Fe-4S binding domain Fer4_21 PF14697.6 EWM25923.1 - 0.02 15.0 10.2 0.14 12.3 10.2 2.1 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 EWM25923.1 - 0.073 13.2 13.4 1.4 9.2 0.7 2.9 3 0 0 3 3 3 0 4Fe-4S binding domain RTP1_C2 PF10304.9 EWM25923.1 - 0.075 12.7 0.9 0.12 12.1 0.1 1.8 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 2 Fer4_3 PF12798.7 EWM25923.1 - 1.5 9.9 12.2 6.3 8.0 1.0 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 EWM25923.1 - 1.7 9.2 9.4 27 5.4 10.5 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 EWM25923.1 - 2.1 8.8 10.0 17 5.9 10.1 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain SCIFF PF13165.6 EWM25923.1 - 3.6 7.6 7.6 1.9 8.5 2.9 2.2 2 0 0 2 2 2 0 Six-cysteine peptide SCIFF Fer4_4 PF12800.7 EWM25923.1 - 5.2 7.8 10.1 7.8 7.3 4.8 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Glyco_hydro_43 PF04616.14 EWM25924.1 - 3.8e-12 46.1 0.2 6.2e-12 45.4 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 PC-Esterase PF13839.6 EWM25925.1 - 3.2e-07 30.4 0.0 0.00034 20.5 0.0 2.8 2 1 1 3 3 3 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Pkinase PF00069.25 EWM25926.1 - 3.8e-60 203.5 0.0 5.3e-60 203.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM25926.1 - 1.7e-47 161.9 0.0 2.6e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EWM25926.1 - 0.00011 21.1 0.8 0.00039 19.3 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 EWM25926.1 - 0.048 12.6 0.0 0.28 10.1 0.0 2.1 1 1 0 1 1 1 0 Haspin like kinase domain NUDIX PF00293.28 EWM25927.1 - 7e-18 64.9 0.2 1.1e-17 64.3 0.2 1.3 1 0 0 1 1 1 1 NUDIX domain Abhydrolase_3 PF07859.13 EWM25928.1 - 5.7e-08 32.9 0.0 7.8e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EWM25928.1 - 6.6e-08 32.3 0.1 4.5e-06 26.3 0.1 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EWM25928.1 - 0.0031 16.8 0.0 0.19 11.0 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 EWM25928.1 - 0.0082 15.8 0.1 0.012 15.3 0.1 1.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 EWM25928.1 - 0.053 13.1 0.0 0.99 8.9 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_4 PF08386.10 EWM25928.1 - 0.083 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein AcetylCoA_hyd_C PF13336.6 EWM25929.1 - 3.3e-58 196.0 0.0 5.2e-58 195.3 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 EWM25929.1 - 3.8e-22 79.3 0.0 7e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain PsbX PF06596.11 EWM25929.1 - 0.17 11.9 0.4 1.9 8.6 0.0 2.4 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) Acetyltransf_1 PF00583.25 EWM25931.1 - 1.1e-11 45.0 0.0 2.2e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EWM25931.1 - 4.2e-08 33.2 0.1 8.1e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EWM25931.1 - 1.5e-05 25.3 0.0 3.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EWM25931.1 - 0.00032 20.8 0.1 0.00084 19.4 0.2 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EWM25931.1 - 0.00038 20.4 0.0 0.001 19.0 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EWM25931.1 - 0.00043 20.3 0.0 0.00081 19.5 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 EWM25931.1 - 0.0012 19.5 0.0 0.0028 18.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EWM25931.1 - 0.0017 18.5 0.0 0.0029 17.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PPDK_N PF01326.19 EWM25933.1 - 3.6e-45 154.7 0.0 3.3e-33 115.4 0.0 2.1 1 1 1 2 2 2 2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain CHGN PF05679.16 EWM25933.1 - 0.051 12.4 0.0 0.072 11.9 0.0 1.1 1 0 0 1 1 1 0 Chondroitin N-acetylgalactosaminyltransferase Acyl_transf_3 PF01757.22 EWM25934.1 - 2.8e-17 62.8 36.2 4.1e-17 62.2 36.2 1.3 1 0 0 1 1 1 1 Acyltransferase family Prefoldin_2 PF01920.20 EWM25937.1 - 2.9e-14 52.9 10.0 3.7e-14 52.6 10.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit Atg14 PF10186.9 EWM25937.1 - 0.011 14.8 2.5 0.014 14.5 2.5 1.2 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF812 PF05667.11 EWM25937.1 - 0.043 12.7 6.7 0.049 12.5 6.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF948 PF06103.11 EWM25937.1 - 0.1 12.8 7.8 1.6 9.0 1.7 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Prefoldin PF02996.17 EWM25937.1 - 0.51 10.3 9.1 3.2 7.7 9.0 2.4 1 1 0 1 1 1 0 Prefoldin subunit Cluap1 PF10234.9 EWM25937.1 - 0.55 9.6 7.4 1.1 8.5 7.4 1.5 1 1 0 1 1 1 0 Clusterin-associated protein-1 DMPK_coil PF08826.10 EWM25937.1 - 0.73 10.0 9.2 0.053 13.6 3.5 2.0 2 1 0 2 2 2 0 DMPK coiled coil domain like Phage_GP20 PF06810.11 EWM25937.1 - 0.8 9.5 12.4 0.16 11.8 7.1 2.0 2 0 0 2 2 2 0 Phage minor structural protein GP20 DUF16 PF01519.16 EWM25937.1 - 0.97 10.0 6.8 0.41 11.1 4.4 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 OmpH PF03938.14 EWM25937.1 - 1.2 9.5 19.0 0.32 11.3 9.6 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) SOGA PF11365.8 EWM25937.1 - 1.2 10.3 6.7 8.3 7.6 1.2 2.3 1 1 0 2 2 2 0 Protein SOGA Spc7 PF08317.11 EWM25937.1 - 3.1 6.6 10.5 4.5 6.1 10.5 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein Mod_r PF07200.13 EWM25937.1 - 4 7.5 10.4 23 5.1 10.4 1.9 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF883 PF05957.13 EWM25937.1 - 7.1 7.3 10.4 1.8 9.2 0.3 2.9 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) PEP-utilizers_C PF02896.18 EWM25939.1 - 8.6e-80 268.0 0.0 1e-79 267.7 0.0 1.0 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.23 EWM25939.1 - 5.3e-13 48.5 0.4 1.8e-12 46.8 0.4 2.0 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain DUF3825 PF12873.7 EWM25939.1 - 0.094 12.2 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3825) Acyltransf_C PF16076.5 EWM25942.1 - 2.7e-07 30.6 0.0 4.1e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase C-terminus Rrn6 PF10214.9 EWM25942.1 - 7.6 4.9 6.4 9.5 4.6 6.4 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor TP_methylase PF00590.20 EWM25943.1 - 6.5e-45 153.7 0.8 1e-44 153.1 0.8 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_2 PF03446.15 EWM25945.1 - 1.6e-43 148.6 1.0 2.3e-43 148.1 1.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EWM25945.1 - 2.7e-34 118.0 2.1 3e-34 117.9 1.2 1.5 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 EWM25945.1 - 1e-05 26.0 0.0 1.8e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EWM25945.1 - 0.0004 20.5 0.1 0.0012 18.9 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 EWM25945.1 - 0.00077 18.9 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 EWM25945.1 - 0.0022 17.6 0.2 0.008 15.8 0.0 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 EWM25945.1 - 0.088 12.7 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Hydrolase_4 PF12146.8 EWM25946.1 - 3.8e-10 39.4 0.3 4.7e-10 39.1 0.3 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EWM25946.1 - 1.2e-09 38.2 0.2 1.7e-09 37.7 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EWM25946.1 - 2.7e-09 38.0 5.7 2.7e-09 38.0 5.7 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family UPF0227 PF05728.12 EWM25946.1 - 0.069 13.1 0.0 0.15 12.0 0.0 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) Esterase PF00756.20 EWM25946.1 - 0.11 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Thioesterase PF00975.20 EWM25946.1 - 0.13 12.4 0.1 0.19 11.8 0.1 1.2 1 0 0 1 1 1 0 Thioesterase domain Pkinase PF00069.25 EWM25947.1 - 4.5e-44 150.8 0.0 5.4e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM25947.1 - 4.1e-24 85.3 0.0 5.3e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EWM25947.1 - 1.5e-06 27.7 0.0 2.1e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EWM25947.1 - 3e-06 27.3 0.1 0.045 13.7 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.22 EWM25947.1 - 0.085 12.4 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 RIO1 family ETC_C1_NDUFA5 PF04716.14 EWM25948.1 - 2.8e-15 55.8 0.2 3.9e-15 55.4 0.2 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region ThiF PF00899.21 EWM25950.1 - 8.9e-25 87.5 0.0 1e-24 87.2 0.0 1.0 1 0 0 1 1 1 1 ThiF family Coprogen_oxidas PF01218.18 EWM25951.1 - 2.9e-132 439.9 0.1 3.4e-132 439.7 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase CRAL_TRIO PF00650.20 EWM25953.1 - 4.7e-07 29.7 0.0 6.3e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EWM25953.1 - 0.011 15.9 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Proteasome PF00227.26 EWM25954.1 - 2.4e-49 167.4 0.2 3.2e-49 167.0 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EWM25954.1 - 3.6e-14 52.1 0.2 7.7e-14 51.1 0.2 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Pmp3 PF01679.17 EWM25957.1 - 0.017 15.3 0.0 0.023 14.9 0.0 1.2 1 0 0 1 1 1 0 Proteolipid membrane potential modulator HSF_DNA-bind PF00447.17 EWM25958.1 - 5.8e-26 91.0 0.8 1.2e-25 89.9 0.8 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding GDP_Man_Dehyd PF16363.5 EWM25959.1 - 2.3e-15 56.8 0.0 2.5e-15 56.7 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase EamA PF00892.20 EWM25961.1 - 3.4e-30 105.0 28.0 5e-16 59.1 12.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family Solute_trans_a PF03619.16 EWM25961.1 - 3.8e-05 23.3 0.6 0.00018 21.1 0.1 2.0 2 0 0 2 2 2 1 Organic solute transporter Ostalpha CRT-like PF08627.10 EWM25961.1 - 0.00053 19.0 1.7 0.00073 18.6 1.7 1.2 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 EWM25961.1 - 0.13 11.6 8.0 0.029 13.7 1.9 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family GDP_Man_Dehyd PF16363.5 EWM25963.1 - 5.2e-104 348.2 0.1 6e-104 348.0 0.1 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EWM25963.1 - 1.1e-58 198.5 0.0 1.5e-58 198.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EWM25963.1 - 1.3e-06 27.8 0.0 1.9e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EWM25963.1 - 5.9e-06 25.6 0.0 8.2e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 EWM25963.1 - 0.026 14.1 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.25 EWM25963.1 - 0.15 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.10 EWM25963.1 - 0.15 12.0 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 KR domain NAD_binding_10 PF13460.6 EWM25963.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.4 1 1 0 1 1 1 0 NAD(P)H-binding LRR_6 PF13516.6 EWM25964.1 - 7.7e-17 59.9 9.4 0.0014 18.5 0.0 6.0 6 0 0 6 6 6 5 Leucine Rich repeat LRR_4 PF12799.7 EWM25964.1 - 1.9e-07 31.2 1.7 3.1 8.4 0.3 5.6 3 1 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EWM25964.1 - 0.00015 21.4 7.0 1.7 8.5 0.4 5.6 4 1 1 5 5 5 2 Leucine rich repeat LRR_1 PF00560.33 EWM25964.1 - 0.0028 17.9 0.7 48 5.1 0.0 5.3 6 0 0 6 6 6 0 Leucine Rich Repeat CWC25 PF12542.8 EWM25965.1 - 0.054 14.4 0.0 0.063 14.2 0.0 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing factor DUF3464 PF11947.8 EWM25966.1 - 9.1e-29 100.1 0.0 1.4e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 Photosynthesis affected mutant 68 adh_short PF00106.25 EWM25967.1 - 1.8e-38 131.9 0.0 2.6e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EWM25967.1 - 2.2e-25 89.6 0.0 3.5e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM25967.1 - 1.6e-11 44.5 0.5 6.4e-11 42.5 0.5 1.8 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 EWM25967.1 - 5.1e-05 22.8 0.0 0.00023 20.6 0.0 1.8 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 EWM25967.1 - 0.011 15.6 0.1 0.031 14.2 0.2 1.7 2 0 0 2 2 2 0 NAD(P)H-binding Epimerase PF01370.21 EWM25967.1 - 0.027 13.9 0.0 1.4 8.4 0.1 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family ArsR PF09824.9 EWM25967.1 - 0.12 11.9 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 ArsR transcriptional regulator HRDC PF00570.23 EWM25968.1 - 1.7e-09 37.5 1.0 8.3e-08 32.1 0.0 2.6 1 1 2 3 3 3 1 HRDC domain DUF2310 PF10071.9 EWM25968.1 - 0.047 13.0 0.0 0.062 12.6 0.0 1.1 1 0 0 1 1 1 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) DEAD PF00270.29 EWM25969.1 - 5e-17 62.2 0.0 6.4e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EWM25969.1 - 0.00052 20.1 0.0 0.0012 18.9 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EWM25970.1 - 3.3e-47 160.5 0.0 5.2e-47 159.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EWM25970.1 - 6.8e-24 84.4 0.0 3e-23 82.3 0.0 2.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EWM25970.1 - 0.00085 19.4 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Synaptobrevin PF00957.21 EWM25971.1 - 4.1e-28 97.0 0.1 6.8e-28 96.3 0.1 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EWM25971.1 - 9.5e-21 73.6 0.0 1.7e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain RPA43_OB PF17875.1 EWM25972.1 - 8.1e-10 39.4 2.8 6.7e-08 33.2 0.0 3.0 2 1 1 3 3 3 2 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 EWM25972.1 - 0.00078 19.8 0.0 0.0018 18.6 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.12 EWM25972.1 - 0.097 12.9 0.2 0.22 11.7 0.0 1.6 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 PCRF PF03462.18 EWM25973.1 - 9.3e-49 165.9 0.8 1.4e-48 165.3 0.0 1.7 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 EWM25973.1 - 2.5e-31 108.0 0.1 4.5e-31 107.2 0.1 1.4 1 0 0 1 1 1 1 RF-1 domain SR-25 PF10500.9 EWM25973.1 - 0.051 13.2 9.8 0.097 12.3 9.8 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Paf1 PF03985.13 EWM25974.1 - 5.9 5.8 6.1 8.9 5.2 6.1 1.2 1 0 0 1 1 1 0 Paf1 Sulfate_transp PF00916.20 EWM25975.1 - 1.2e-26 93.4 3.0 1.4e-24 86.6 0.2 2.4 2 1 1 3 3 3 2 Sulfate permease family STAS PF01740.21 EWM25975.1 - 1.9e-13 50.0 0.0 3.5e-13 49.2 0.0 1.4 1 1 0 1 1 1 1 STAS domain STAS_2 PF13466.6 EWM25975.1 - 2.1e-06 28.0 0.6 2.9e-05 24.3 0.2 2.6 2 0 0 2 2 2 1 STAS domain PX PF00787.24 EWM25978.1 - 0.017 15.1 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 PX domain SQHop_cyclase_C PF13243.6 EWM25979.1 - 9.1e-29 100.6 0.0 1.2e-28 100.2 0.0 1.0 1 0 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 EWM25979.1 - 1.1e-11 44.3 5.0 8.5e-09 35.0 2.5 3.2 2 1 0 2 2 2 2 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 EWM25979.1 - 0.0022 17.4 0.0 0.99 8.7 0.0 2.1 2 0 0 2 2 2 2 Pectic acid lyase SQHop_cyclase_N PF13249.6 EWM25979.1 - 0.0044 16.2 0.0 1.5 7.9 0.0 2.1 2 0 0 2 2 2 2 Squalene-hopene cyclase N-terminal domain TED_complement PF07678.14 EWM25979.1 - 0.0055 15.8 0.0 1.4 7.9 0.0 2.1 1 1 1 2 2 2 2 A-macroglobulin TED domain 3D PF06725.11 EWM25982.1 - 0.043 14.0 0.2 0.12 12.5 0.2 1.7 1 0 0 1 1 1 0 3D domain AAA_11 PF13086.6 EWM25982.1 - 1.4 8.6 5.9 3.2 7.5 5.9 1.5 1 0 0 1 1 1 0 AAA domain PEP-CTERM PF07589.11 EWM25982.1 - 4.9 7.4 5.7 23 5.2 5.7 2.3 1 0 0 1 1 1 0 PEP-CTERM motif DnaJ PF00226.31 EWM25983.1 - 4.7e-27 93.9 2.0 7.6e-27 93.2 2.0 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 EWM25983.1 - 5.6e-27 94.6 0.2 8.7e-27 94.0 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_C PF01556.18 EWM25984.1 - 6.2e-27 94.5 0.2 9.5e-27 93.9 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EWM25984.1 - 1.5e-13 50.6 0.8 2.7e-13 49.8 0.8 1.4 1 0 0 1 1 1 1 DnaJ domain E1-E2_ATPase PF00122.20 EWM25985.1 - 4.7e-49 166.4 4.2 9.7e-47 158.8 2.5 2.9 2 0 0 2 2 2 2 E1-E2 ATPase Hydrolase PF00702.26 EWM25985.1 - 2.6e-16 60.6 0.1 1.3e-15 58.3 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EWM25985.1 - 1.2e-13 50.5 0.1 6.4e-13 48.2 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EWM25985.1 - 0.00037 20.3 0.4 0.0023 17.7 0.1 2.1 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase FumaraseC_C PF10415.9 EWM25986.1 - 0.077 13.4 0.0 0.24 11.8 0.0 1.8 1 0 0 1 1 1 0 Fumarase C C-terminus COX17 PF05051.13 EWM25988.1 - 9.8e-18 64.2 7.5 1.8e-17 63.4 7.5 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) E1-E2_ATPase PF00122.20 EWM25989.1 - 2.8e-46 157.3 2.0 2.8e-46 157.3 2.0 2.9 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EWM25989.1 - 1.3e-16 61.6 0.2 8.4e-16 58.9 0.2 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EWM25989.1 - 3.6e-14 52.2 1.0 7.7e-14 51.1 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EWM25989.1 - 9.8e-05 22.2 0.0 0.00087 19.1 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ion_trans_2 PF07885.16 EWM25989.1 - 8.1 6.5 8.9 0.54 10.3 0.1 3.2 2 1 1 3 3 3 0 Ion channel E1-E2_ATPase PF00122.20 EWM25990.1 - 2.4e-46 157.5 2.0 2.4e-46 157.5 2.0 2.9 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EWM25990.1 - 1e-16 61.9 0.2 7.1e-16 59.1 0.2 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EWM25990.1 - 2.6e-14 52.7 0.8 6.8e-14 51.3 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EWM25990.1 - 8.2e-05 22.5 0.0 0.00078 19.3 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ion_trans_2 PF07885.16 EWM25990.1 - 7 6.7 9.2 0.48 10.4 0.1 3.3 2 1 1 3 3 3 0 Ion channel Baculo_PEP_C PF04513.12 EWM25991.1 - 0.084 12.9 0.2 0.32 11.0 0.2 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lectin_N PF03954.14 EWM25991.1 - 0.31 10.8 3.6 0.4 10.4 1.7 2.1 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain CorA PF01544.18 EWM25991.1 - 0.61 9.3 14.7 0.41 9.9 2.8 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Spc7 PF08317.11 EWM25991.1 - 2.3 7.0 22.3 0.13 11.1 10.2 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein ApoLp-III PF07464.11 EWM25991.1 - 4 7.5 9.2 2.5 8.2 0.4 2.3 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF1664 PF07889.12 EWM25991.1 - 5.9 6.9 7.3 6.6 6.8 2.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) CorA PF01544.18 EWM25992.1 - 0.12 11.7 13.9 0.074 12.4 2.3 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Lectin_N PF03954.14 EWM25992.1 - 0.12 12.1 1.4 0.34 10.7 1.4 1.7 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF1664 PF07889.12 EWM25992.1 - 4.7 7.3 7.4 6.3 6.9 1.6 2.8 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) ApoLp-III PF07464.11 EWM25992.1 - 7.7 6.6 10.0 2.7 8.1 0.4 2.3 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) AIRS_C PF02769.22 EWM25994.1 - 1.1e-14 54.8 1.8 5e-14 52.7 1.8 1.9 1 1 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 EWM25994.1 - 6e-13 49.3 0.2 1.7e-12 47.8 0.0 1.9 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain Pyr_redox_2 PF07992.14 EWM25994.1 - 0.00049 19.4 0.0 0.00078 18.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_9 PF00759.19 EWM25995.1 - 8e-34 117.8 0.0 9.9e-34 117.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 TPR_19 PF14559.6 EWM25996.1 - 4.2e-05 24.0 0.9 0.00014 22.3 0.9 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 EWM25996.1 - 0.01 16.1 4.8 0.043 14.1 2.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_MalT PF17874.1 EWM25996.1 - 0.011 15.1 3.9 0.015 14.6 3.9 1.1 1 0 0 1 1 1 0 MalT-like TPR region TPR_14 PF13428.6 EWM25996.1 - 0.018 15.8 2.0 0.018 15.8 2.0 2.9 2 2 2 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EWM25996.1 - 0.091 13.0 2.2 0.14 12.4 0.8 2.0 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EWM25996.1 - 0.14 12.4 6.6 2.4 8.5 3.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 EWM25996.1 - 0.61 10.9 9.1 0.26 12.0 2.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 EWM25996.1 - 0.7 10.6 11.7 0.05 14.2 4.4 2.8 3 1 0 3 3 3 0 Tetratricopeptide repeat Hamartin PF04388.12 EWM25996.1 - 3 6.4 7.1 3.9 6.0 6.5 1.3 1 1 0 1 1 1 0 Hamartin protein MoCF_biosynth PF00994.24 EWM25998.1 - 1.5e-20 73.3 0.1 1.7e-20 73.2 0.1 1.0 1 0 0 1 1 1 1 Probable molybdopterin binding domain TPR_12 PF13424.6 EWM25999.1 - 0.0016 18.7 0.2 0.01 16.1 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat RRM_1 PF00076.22 EWM26001.1 - 3.1e-18 65.3 0.1 8.1e-18 64.0 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EWM26001.1 - 0.012 15.3 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EWM26001.1 - 0.047 13.8 0.1 0.16 12.0 0.0 2.0 1 1 1 2 2 2 0 Limkain b1 MoeA_N PF03453.17 EWM26002.1 - 3.1e-27 95.3 0.1 3.9e-27 94.9 0.1 1.1 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) SET PF00856.28 EWM26005.1 - 2.6e-08 34.4 0.0 2.1e-06 28.2 0.0 2.4 1 1 0 1 1 1 1 SET domain zf-met PF12874.7 EWM26007.1 - 6.2e-09 35.9 5.9 6.1e-08 32.8 0.9 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EWM26007.1 - 1e-07 32.0 0.9 1e-07 32.0 0.9 2.4 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EWM26007.1 - 1.1e-06 28.9 4.9 0.0011 19.2 1.1 2.1 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EWM26007.1 - 0.00033 21.3 5.2 0.026 15.3 0.8 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger AKAP95 PF04988.12 EWM26007.1 - 0.001 19.4 5.6 0.25 11.6 0.7 2.1 2 0 0 2 2 2 2 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_3rep PF18868.1 EWM26007.1 - 0.0024 18.5 1.0 0.42 11.3 0.1 2.1 1 1 1 2 2 2 2 Zinc finger C2H2-type, 3 repeats zf-BED PF02892.15 EWM26007.1 - 0.003 17.5 1.5 0.29 11.2 0.4 2.2 2 0 0 2 2 2 1 BED zinc finger zf-DBF PF07535.12 EWM26007.1 - 0.0035 17.4 5.4 0.42 10.8 0.2 2.3 1 1 1 2 2 2 2 DBF zinc finger zf-C2HE PF16278.5 EWM26007.1 - 0.0086 16.5 5.5 0.52 10.8 2.0 2.2 1 1 1 2 2 2 2 C2HE / C2H2 / C2HC zinc-binding finger DUF4187 PF13821.6 EWM26007.1 - 0.011 15.4 1.4 0.4 10.5 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4187) zf-C2H2_9 PF16293.5 EWM26007.1 - 0.023 14.5 0.2 5.9 6.8 0.1 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf_C2H2_ZHX PF18387.1 EWM26007.1 - 0.027 14.1 0.8 0.047 13.3 0.8 1.4 1 1 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2 PF00096.26 EWM26007.1 - 0.2 12.2 8.5 0.64 10.6 1.7 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type ATG101 PF07855.12 EWM26010.1 - 1.9e-25 89.6 0.0 1.4e-24 86.8 0.0 1.9 1 1 0 1 1 1 1 Autophagy-related protein 101 ATG101 PF07855.12 EWM26011.1 - 1.3e-25 90.2 0.0 9.4e-25 87.4 0.0 1.9 1 1 0 1 1 1 1 Autophagy-related protein 101 M-inducer_phosp PF06617.13 EWM26011.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 M-phase inducer phosphatase FA_hydroxylase PF04116.13 EWM26012.1 - 1.2e-11 45.1 17.9 1.4e-11 44.8 14.6 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily FAST_1 PF06743.15 EWM26013.1 - 0.0067 16.3 1.6 12 5.9 0.1 4.7 5 0 0 5 5 5 1 FAST kinase-like protein, subdomain 1 RAP PF08373.10 EWM26013.1 - 0.013 15.6 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 RAP domain PGM_PMM_IV PF00408.20 EWM26015.1 - 1.2e-10 41.3 0.0 3.6e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 EWM26015.1 - 1.6e-07 31.5 0.1 5.5e-07 29.8 0.1 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_I PF02878.16 EWM26015.1 - 1.4e-05 24.8 0.0 4e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Abhydrolase_3 PF07859.13 EWM26016.1 - 7.1e-13 48.9 0.0 8.3e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Fer2 PF00111.27 EWM26017.1 - 5.9e-09 35.8 0.1 1e-08 35.0 0.1 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 EWM26017.1 - 0.026 14.6 0.3 0.077 13.1 0.3 1.8 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain PSI PF01437.25 EWM26017.1 - 0.95 10.1 5.7 4.2 8.0 0.6 2.3 2 0 0 2 2 2 0 Plexin repeat PCI PF01399.27 EWM26019.1 - 5.2e-20 71.9 0.3 1.7e-19 70.3 0.3 1.9 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.17 EWM26019.1 - 0.00022 21.1 3.3 5.5 7.4 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat SAC3_GANP PF03399.16 EWM26019.1 - 0.0033 16.9 0.4 0.0059 16.0 0.4 1.3 1 0 0 1 1 1 1 SAC3/GANP family TPR_14 PF13428.6 EWM26019.1 - 0.006 17.3 0.2 15 6.7 0.0 3.5 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EWM26019.1 - 0.0081 16.4 4.1 11 6.4 0.1 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat CSN8_PSD8_EIF3K PF10075.9 EWM26019.1 - 0.021 14.8 1.8 0.075 13.0 0.3 2.3 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family TPR_6 PF13174.6 EWM26019.1 - 0.03 14.9 1.8 7 7.5 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Spore_III_AB PF09548.10 EWM26019.1 - 0.031 14.4 2.4 1.1 9.3 0.2 2.9 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Sigma70_r4 PF04545.16 EWM26019.1 - 0.049 13.1 1.6 0.16 11.5 1.6 1.9 1 0 0 1 1 1 0 Sigma-70, region 4 TPR_8 PF13181.6 EWM26019.1 - 0.075 13.3 0.2 1.2 9.5 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DDRGK PF09756.9 EWM26019.1 - 0.082 12.5 0.7 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 DDRGK domain HTH_Mga PF08280.11 EWM26019.1 - 0.11 12.5 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain TPR_MalT PF17874.1 EWM26019.1 - 0.4 10.0 5.0 1.3 8.3 0.1 3.3 3 1 1 4 4 4 0 MalT-like TPR region Abhydrolase_3 PF07859.13 EWM26021.1 - 1.8e-14 54.1 0.5 3.6e-14 53.1 0.5 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EWM26021.1 - 4.2e-06 25.9 0.0 6.7e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Redoxin PF08534.10 EWM26023.1 - 3e-29 101.6 0.0 3.3e-29 101.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EWM26023.1 - 5.6e-11 42.4 0.0 6.4e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF3253 PF11625.8 EWM26025.1 - 1e-23 83.3 0.3 1.3e-23 83.0 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3253) FXR_C1 PF16096.5 EWM26027.1 - 0.0067 16.6 2.7 0.017 15.3 2.7 1.7 1 0 0 1 1 1 1 Fragile X-related 1 protein C-terminal region 2 Cupin_8 PF13621.6 EWM26030.1 - 0.002 17.9 0.0 0.0021 17.8 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain PSI PF01437.25 EWM26031.1 - 0.00057 20.4 9.0 0.001 19.6 9.0 1.4 1 0 0 1 1 1 1 Plexin repeat Vps36-NZF-N PF16988.5 EWM26033.1 - 0.03 13.7 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain HECT PF00632.25 EWM26034.1 - 1.7e-11 44.2 0.0 2.1e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Evr1_Alr PF04777.13 EWM26035.1 - 6.5e-18 65.1 4.4 2.3e-09 37.6 0.3 2.5 2 0 0 2 2 2 2 Erv1 / Alr family zf-C2HC_2 PF13913.6 EWM26035.1 - 0.12 12.3 1.9 12 5.9 0.2 3.7 3 0 0 3 3 3 0 zinc-finger of a C2HC-type HECT PF00632.25 EWM26036.1 - 1.7e-30 106.6 0.0 1.9e-30 106.4 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) OGFr_N PF04664.13 EWM26036.1 - 0.075 12.5 0.2 0.12 11.9 0.2 1.3 1 0 0 1 1 1 0 Opioid growth factor receptor (OGFr) conserved region PRP8_domainIV PF12134.8 EWM26039.1 - 2.1e-49 168.3 0.0 2.6e-49 168.0 0.0 1.0 1 0 0 1 1 1 1 PRP8 domain IV core CG-1 PF03859.16 EWM26039.1 - 0.11 12.3 0.0 1.6 8.5 0.0 2.0 2 0 0 2 2 2 0 CG-1 domain RRM_4 PF10598.9 EWM26040.1 - 4.2e-41 139.2 1.4 4.6e-41 139.1 1.4 1.0 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 SH3_17 PF18350.1 EWM26040.1 - 0.079 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease SH3 domain PROCN PF08083.11 EWM26041.1 - 4.3e-24 85.0 0.0 5e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 PROCN (NUC071) domain PROCN PF08083.11 EWM26042.1 - 1.2e-99 333.8 5.0 1.4e-99 333.6 5.0 1.0 1 0 0 1 1 1 1 PROCN (NUC071) domain Ribosomal_L23eN PF03939.13 EWM26043.1 - 4.3e-14 52.5 11.0 7.5e-14 51.7 11.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 EWM26043.1 - 1.1e-05 25.8 0.2 1.1e-05 25.8 0.2 1.9 1 1 1 2 2 2 1 Ribosomal protein L23 CSTF1_dimer PF16699.5 EWM26047.1 - 0.11 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Cleavage stimulation factor subunit 1, dimerisation domain Apt1 PF10351.9 EWM26050.1 - 0.38 9.6 4.8 0.4 9.5 4.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CCDC24 PF15669.5 EWM26050.1 - 0.76 9.6 3.8 0.9 9.4 3.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family PI3K_1B_p101 PF10486.9 EWM26050.1 - 4.4 5.0 5.6 5.3 4.7 5.6 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Macoilin PF09726.9 EWM26050.1 - 6.6 5.2 7.4 7.4 5.0 7.4 1.1 1 0 0 1 1 1 0 Macoilin family TrkA_C PF02080.21 EWM26055.1 - 0.12 12.2 0.1 1.2 9.0 0.1 2.2 2 0 0 2 2 2 0 TrkA-C domain Chitin_synth_2 PF03142.15 EWM26057.1 - 0.27 9.8 1.0 0.31 9.6 1.0 1.1 1 0 0 1 1 1 0 Chitin synthase YwiC PF14256.6 EWM26058.1 - 0.1 12.9 6.8 0.16 12.3 0.5 2.1 1 1 1 2 2 2 0 YwiC-like protein CBM_14 PF01607.24 EWM26062.1 - 0.76 10.0 5.6 0.41 10.8 0.5 2.5 2 0 0 2 2 2 0 Chitin binding Peritrophin-A domain MTABC_N PF16185.5 EWM26066.1 - 3.8e-06 26.6 0.1 4.7e-06 26.3 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ABC-transporter N-terminal five TM region Ald_Xan_dh_C2 PF02738.18 EWM26067.1 - 1.6e-15 56.6 0.0 2.1e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase CotJA PF11007.8 EWM26068.1 - 0.072 12.9 0.4 0.15 11.9 0.2 1.6 2 0 0 2 2 2 0 Spore coat associated protein JA (CotJA) His_Phos_1 PF00300.22 EWM26069.1 - 2.5e-17 63.2 0.1 3.6e-17 62.7 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF5362 PF17319.2 EWM26071.1 - 0.06 13.2 6.0 0.13 12.1 0.0 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5362) DUF5362 PF17319.2 EWM26072.1 - 0.018 14.9 5.1 0.1 12.5 0.0 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5362) DUF3464 PF11947.8 EWM26072.1 - 0.14 11.9 0.0 0.46 10.2 0.0 1.8 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Mnd1 PF03962.15 EWM26073.1 - 1.9e-22 79.3 0.0 4.3e-22 78.1 0.0 1.7 1 0 0 1 1 1 1 Mnd1 HTH domain LZ3wCH PF18517.1 EWM26073.1 - 6.2e-18 64.6 0.4 2e-17 63.0 0.0 2.1 2 0 0 2 2 2 1 Leucine zipper with capping helix domain End3 PF12761.7 EWM26073.1 - 0.003 17.8 0.8 0.0035 17.5 0.8 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 TPR_MLP1_2 PF07926.12 EWM26073.1 - 0.014 15.4 3.2 0.022 14.8 3.2 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein TMPIT PF07851.13 EWM26073.1 - 0.019 14.2 1.1 0.027 13.7 1.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein Pkip-1 PF06878.11 EWM26073.1 - 0.021 14.9 0.8 0.034 14.3 0.8 1.3 1 0 0 1 1 1 0 Pkip-1 protein Spc7 PF08317.11 EWM26073.1 - 0.038 12.9 3.1 0.055 12.3 3.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein FemAB PF02388.16 EWM26073.1 - 0.064 12.1 2.0 0.096 11.5 2.0 1.2 1 0 0 1 1 1 0 FemAB family DHR10 PF18595.1 EWM26073.1 - 0.082 13.0 6.4 0.15 12.2 6.4 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DOR PF14839.6 EWM26073.1 - 0.13 12.2 2.0 0.21 11.5 2.0 1.2 1 0 0 1 1 1 0 DOR family DUF5082 PF16888.5 EWM26073.1 - 0.48 10.7 4.9 3.5 7.9 3.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Ribosomal_L12 PF00542.19 EWM26076.1 - 5.2e-26 90.8 11.2 5.2e-26 90.8 11.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 EWM26076.1 - 2.5e-06 27.1 2.7 0.0004 20.0 0.8 2.8 2 1 0 2 2 2 2 Ribosomal protein L7/L12 dimerisation domain TFIIS_M PF07500.14 EWM26077.1 - 7.6e-11 42.5 0.0 1.3e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SAP130_C PF16014.5 EWM26077.1 - 2.7 7.0 5.0 4.5 6.3 5.0 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus ABC_tran PF00005.27 EWM26078.1 - 3.4e-52 176.6 0.0 4.9e-25 88.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EWM26078.1 - 6.8e-18 65.5 0.1 9.5e-06 25.6 0.0 4.1 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 EWM26078.1 - 3.1e-12 46.3 8.2 3.5e-09 36.6 0.7 2.6 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 EWM26078.1 - 1.7e-10 40.7 2.9 0.0084 15.6 0.1 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EWM26078.1 - 1.2e-05 25.3 0.1 0.0078 16.3 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EWM26078.1 - 2.2e-05 24.9 2.2 0.24 11.8 0.1 3.0 2 1 1 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 EWM26078.1 - 3.9e-05 23.3 1.2 0.038 13.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EWM26078.1 - 0.00015 21.7 0.8 0.024 14.5 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 EWM26078.1 - 0.00022 21.8 0.3 0.52 10.9 0.0 3.1 2 1 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 EWM26078.1 - 0.00037 20.6 0.0 0.87 9.6 0.0 2.6 2 0 0 2 2 2 2 Dynamin family MeaB PF03308.16 EWM26078.1 - 0.00083 18.4 0.3 0.39 9.7 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_15 PF13175.6 EWM26078.1 - 0.0012 18.6 0.1 1.3 8.6 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.6 EWM26078.1 - 0.0025 18.1 0.3 3.6 7.8 0.7 3.7 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EWM26078.1 - 0.0068 16.8 0.0 1.1 9.7 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_23 PF13476.6 EWM26078.1 - 0.0096 16.4 0.1 0.0096 16.4 0.1 2.8 4 0 0 4 4 2 1 AAA domain FeoB_N PF02421.18 EWM26078.1 - 0.01 15.4 0.1 0.25 10.9 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B NACHT PF05729.12 EWM26078.1 - 0.016 15.1 1.3 10 6.0 0.0 3.3 3 0 0 3 3 3 0 NACHT domain ATP-synt_ab PF00006.25 EWM26078.1 - 0.021 14.5 0.0 6.1 6.4 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.6 EWM26078.1 - 0.023 14.7 0.0 6 6.9 0.0 3.7 4 0 0 4 4 4 0 AAA domain SbcCD_C PF13558.6 EWM26078.1 - 0.023 14.9 2.3 14 6.0 0.5 3.7 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 EWM26078.1 - 0.023 14.8 0.2 6.5 6.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 EWM26078.1 - 0.025 13.8 0.1 2.4 7.3 0.0 2.9 4 0 0 4 4 4 0 NB-ARC domain DLIC PF05783.11 EWM26078.1 - 0.029 13.2 0.1 5.6 5.7 0.0 2.2 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA PF00004.29 EWM26078.1 - 0.031 14.7 0.0 1.8 9.0 0.0 3.3 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EWM26078.1 - 0.036 14.3 1.5 11 6.3 0.4 3.5 3 1 0 3 3 3 0 AAA domain Roc PF08477.13 EWM26078.1 - 0.069 13.4 1.1 6.5 7.0 0.0 2.7 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 EWM26078.1 - 0.073 12.6 0.2 14 5.2 0.0 3.6 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 EWM26078.1 - 0.18 11.5 0.3 11 5.7 0.1 2.9 3 0 0 3 3 3 0 AAA domain Ploopntkinase1 PF18748.1 EWM26078.1 - 0.19 11.2 0.0 2.3 7.7 0.0 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 DUF87 PF01935.17 EWM26078.1 - 1.7 8.7 6.2 26 4.8 0.0 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_13 PF13166.6 EWM26078.1 - 7.1 5.1 5.0 9.8 4.7 0.0 2.9 4 0 0 4 4 4 0 AAA domain cobW PF02492.19 EWM26079.1 - 2.8e-45 154.1 0.0 4.3e-45 153.5 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EWM26079.1 - 1.4e-17 63.4 0.0 1.2e-16 60.4 0.0 2.2 1 1 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain Viral_helicase1 PF01443.18 EWM26079.1 - 0.0032 17.2 0.1 0.029 14.1 0.0 2.2 1 1 1 2 2 2 1 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 EWM26079.1 - 0.0073 16.3 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 EWM26079.1 - 0.0076 16.6 0.0 0.02 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain MobB PF03205.14 EWM26079.1 - 0.01 15.7 0.1 0.025 14.5 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 EWM26079.1 - 0.01 16.4 0.0 0.023 15.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EWM26079.1 - 0.037 14.2 0.0 0.086 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EWM26079.1 - 0.062 12.5 0.0 0.094 11.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 EWM26079.1 - 0.12 12.1 0.0 0.39 10.5 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EWM26079.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 EWM26079.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase ABC_tran PF00005.27 EWM26079.1 - 0.15 12.5 0.7 0.37 11.3 0.0 1.9 2 0 0 2 2 2 0 ABC transporter MeaB PF03308.16 EWM26079.1 - 0.19 10.7 0.6 1.7 7.6 0.2 2.4 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_14 PF13173.6 EWM26079.1 - 0.21 11.6 0.0 0.41 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zip PF02535.22 EWM26079.1 - 1.6 7.8 18.7 2.8 7.1 18.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter FAM76 PF16046.5 EWM26079.1 - 3.2 7.0 7.6 7.6 5.8 7.6 1.6 1 0 0 1 1 1 0 FAM76 protein SPX PF03105.19 EWM26079.1 - 5.9 6.7 12.0 0.77 9.6 5.4 2.0 2 0 0 2 2 2 0 SPX domain Trypsin_2 PF13365.6 EWM26080.1 - 3.2e-07 31.4 0.0 4.4e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Mcm10 PF09332.11 EWM26081.1 - 1.7e-15 57.3 6.8 3.7e-15 56.2 6.8 1.5 1 1 0 1 1 1 1 Mcm10 replication factor Ribosomal_L37e PF01907.19 EWM26081.1 - 1.5 9.1 4.6 6 7.1 0.1 3.0 3 0 0 3 3 3 0 Ribosomal protein L37e DZR PF12773.7 EWM26081.1 - 8.7 6.5 7.9 6.5 6.9 3.5 2.8 2 1 0 2 2 2 0 Double zinc ribbon DENN PF02141.21 EWM26082.1 - 5.2e-29 101.5 0.1 8.9e-29 100.8 0.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain ENTH PF01417.20 EWM26082.1 - 2.1e-10 40.7 0.0 3.4e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 ENTH domain DnaJ PF00226.31 EWM26083.1 - 8.6e-22 77.0 1.3 1.5e-21 76.2 1.3 1.4 1 0 0 1 1 1 1 DnaJ domain Phage_head_fibr PF11133.8 EWM26083.1 - 0.00018 21.0 0.0 0.00028 20.4 0.0 1.3 1 0 0 1 1 1 1 Head fiber protein GBR_NSP5 PF17580.2 EWM26083.1 - 0.071 12.9 1.0 0.7 9.7 0.0 2.2 2 0 0 2 2 2 0 Group B Rotavirus Non-structural protein 5 Snapin_Pallidin PF14712.6 EWM26083.1 - 2 8.9 5.3 4.1 7.9 5.3 1.5 1 0 0 1 1 1 0 Snapin/Pallidin ADIP PF11559.8 EWM26083.1 - 2.6 8.1 6.4 5.1 7.2 6.4 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 EWM26083.1 - 3.7 6.4 7.1 5.7 5.7 7.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein PEP_mutase PF13714.6 EWM26084.1 - 1e-39 136.4 0.2 1.2e-39 136.2 0.2 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 EWM26084.1 - 5.8e-09 35.0 0.2 8.3e-09 34.5 0.2 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Cupin_4 PF08007.12 EWM26085.1 - 3e-68 230.6 0.0 2.9e-67 227.4 0.0 2.0 1 1 0 1 1 1 1 Cupin superfamily protein Armet PF10208.9 EWM26085.1 - 1.4e-30 106.2 8.8 2.3e-30 105.4 8.8 1.3 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding AraC_binding PF02311.19 EWM26085.1 - 0.00013 21.9 0.0 0.00029 20.7 0.0 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain SAP PF02037.27 EWM26085.1 - 0.00043 20.0 0.1 0.0014 18.3 0.1 1.9 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 EWM26085.1 - 0.013 15.2 0.3 0.047 13.4 0.0 2.0 2 0 0 2 2 2 0 HeH/LEM domain Cupin_2 PF07883.11 EWM26085.1 - 0.05 13.3 0.0 0.32 10.8 0.0 2.3 3 0 0 3 3 3 0 Cupin domain DUF3377 PF11857.8 EWM26086.1 - 0.093 12.7 2.1 1.8 8.5 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Dzip-like_N PF13815.6 EWM26086.1 - 0.23 11.4 7.9 3.8 7.5 2.7 2.7 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Sec8_exocyst PF04048.14 EWM26087.1 - 0.4 10.5 6.0 0.085 12.7 0.9 2.5 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain FlaC_arch PF05377.11 EWM26087.1 - 9.5 6.7 7.2 26 5.3 0.1 4.1 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF3080 PF11279.8 EWM26088.1 - 0.0041 16.4 2.5 0.0041 16.4 2.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3080) Sec8_exocyst PF04048.14 EWM26088.1 - 0.56 10.1 6.5 0.12 12.3 1.2 2.4 2 1 0 3 3 3 0 Sec8 exocyst complex component specific domain YEATS PF03366.16 EWM26089.1 - 4.9e-24 84.1 1.1 8e-24 83.4 1.1 1.3 1 0 0 1 1 1 1 YEATS family CDC27 PF09507.10 EWM26089.1 - 0.035 13.5 1.1 0.052 12.9 1.1 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PAXNEB PF05625.11 EWM26090.1 - 3.3e-68 230.5 0.0 4.2e-68 230.2 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein GNAT_C PF18164.1 EWM26090.1 - 0.07 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 GNAT-like C-terminal domain Chorismate_bind PF00425.18 EWM26091.1 - 3.1e-62 210.5 0.0 4.4e-31 108.4 0.0 2.3 2 0 0 2 2 2 2 chorismate binding enzyme TPP_enzyme_N PF02776.18 EWM26091.1 - 1.5e-33 115.8 0.4 1.5e-33 115.8 0.4 2.5 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain MR_MLE_C PF13378.6 EWM26091.1 - 3.5e-18 66.0 0.0 1.3e-17 64.2 0.0 1.9 1 0 0 1 1 1 1 Enolase C-terminal domain-like Abhydrolase_1 PF00561.20 EWM26091.1 - 2e-15 57.1 0.0 8.4e-15 55.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold TPP_enzyme_M_2 PF16582.5 EWM26091.1 - 6.9e-14 52.0 0.0 1.3e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Middle domain of thiamine pyrophosphate Hydrolase_4 PF12146.8 EWM26091.1 - 2.1e-06 27.2 0.0 4.3e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 TPP_enzyme_C PF02775.21 EWM26091.1 - 0.00027 20.7 0.2 0.00089 19.1 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EWM26091.1 - 0.0027 17.4 0.0 0.0057 16.4 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Esterase PF00756.20 EWM26091.1 - 0.0069 16.1 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 EWM26091.1 - 0.022 14.6 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 EWM26091.1 - 0.035 14.2 0.2 0.091 12.9 0.2 1.7 1 0 0 1 1 1 0 Thioesterase domain Ndr PF03096.14 EWM26091.1 - 0.19 10.4 0.0 0.32 9.7 0.0 1.2 1 0 0 1 1 1 0 Ndr family PLAC8 PF04749.17 EWM26092.1 - 3.4e-13 50.4 2.0 5.7e-13 49.7 2.0 1.4 1 0 0 1 1 1 1 PLAC8 family DUF1129 PF06570.11 EWM26092.1 - 0.0045 16.5 0.2 0.0063 16.0 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1129) WD40 PF00400.32 EWM26094.1 - 1.6e-21 76.2 7.6 0.00022 22.0 0.0 7.3 7 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM26094.1 - 2.6e-12 46.9 0.0 0.0011 19.2 0.0 6.1 3 1 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EWM26094.1 - 0.00026 20.1 0.0 1.8 7.5 0.0 3.7 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EWM26094.1 - 0.0044 16.9 0.0 7.9 6.6 0.0 3.5 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Nup160 PF11715.8 EWM26094.1 - 0.015 14.0 0.1 0.092 11.4 0.0 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 eIF2A PF08662.11 EWM26094.1 - 0.069 13.0 0.0 17 5.2 0.0 2.8 2 2 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.9 EWM26094.1 - 0.099 12.3 0.0 0.78 9.5 0.0 2.6 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature Menin PF05053.13 EWM26094.1 - 0.22 9.9 5.8 0.34 9.2 5.8 1.2 1 0 0 1 1 1 0 Menin Frtz PF11768.8 EWM26094.1 - 0.23 9.7 0.0 15 3.7 0.0 2.4 1 1 2 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Malic_M PF03949.15 EWM26095.1 - 2.9e-84 282.4 0.2 4.3e-84 281.8 0.2 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EWM26095.1 - 6.6e-65 218.3 0.0 1.3e-64 217.4 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF4485 PF14846.6 EWM26096.1 - 0.0095 16.0 0.2 0.024 14.7 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4485) PSK_trans_fac PF07704.11 EWM26096.1 - 5.9 7.7 8.2 28 5.5 5.6 2.9 1 1 1 2 2 2 0 Rv0623-like transcription factor S1 PF00575.23 EWM26097.1 - 3.9e-36 123.2 1.9 1.3e-14 54.3 0.3 3.3 3 0 0 3 3 3 3 S1 RNA binding domain DUF2625 PF10946.8 EWM26097.1 - 0.15 11.1 0.1 4.1 6.4 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF2625 OKR_DC_1_N PF03709.15 EWM26097.1 - 0.18 12.1 0.1 25 5.2 0.0 2.4 1 1 1 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain DUF866 PF05907.13 EWM26098.1 - 5.7e-25 88.0 0.0 6.4e-25 87.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) BPL_LplA_LipB PF03099.19 EWM26099.1 - 9.5e-12 45.0 0.1 3.5e-11 43.1 0.0 1.9 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family adh_short PF00106.25 EWM26100.1 - 9.1e-23 80.7 0.0 1.8e-20 73.2 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EWM26100.1 - 6e-15 55.4 0.0 7.9e-14 51.8 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM26100.1 - 0.00099 19.1 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EWM26100.1 - 0.007 16.3 0.0 0.022 14.7 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EWM26100.1 - 0.021 14.3 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family zf-HIT PF04438.16 EWM26102.1 - 2.3e-08 33.8 14.6 3.6e-08 33.1 14.6 1.3 1 0 0 1 1 1 1 HIT zinc finger DUF4715 PF15835.5 EWM26102.1 - 0.011 15.8 1.9 0.015 15.4 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4715) DUF3799 PF12684.7 EWM26102.1 - 0.017 14.9 0.3 0.023 14.4 0.3 1.1 1 0 0 1 1 1 0 PDDEXK-like domain of unknown function (DUF3799) DUF4375 PF14300.6 EWM26102.1 - 0.029 14.6 0.8 0.045 14.0 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) DUF4661 PF15576.6 EWM26102.1 - 0.43 10.4 4.0 0.61 10.0 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) zf-C2H2_3 PF13878.6 EWM26102.1 - 5.2 7.0 8.5 2.7 7.9 3.3 2.4 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO PHD PF00628.29 EWM26103.1 - 3.4e-11 42.9 6.8 7.2e-11 41.8 6.8 1.5 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 EWM26103.1 - 9.6e-06 25.4 5.4 2.5e-05 24.1 5.4 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 PHD_2 PF13831.6 EWM26103.1 - 0.0044 16.5 7.2 0.013 15.0 7.2 1.9 1 1 0 1 1 1 1 PHD-finger C1_1 PF00130.22 EWM26103.1 - 0.064 13.1 3.5 0.073 13.0 1.0 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) YlqD PF11068.8 EWM26103.1 - 0.083 13.3 1.7 0.18 12.2 0.0 2.3 2 0 0 2 2 2 0 YlqD protein C1_2 PF03107.16 EWM26103.1 - 0.94 9.8 4.4 4.4 7.7 1.6 2.7 3 0 0 3 3 3 0 C1 domain OrfB_Zn_ribbon PF07282.11 EWM26103.1 - 1.7 8.6 6.0 48 4.0 0.0 2.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DEAD PF00270.29 EWM26104.1 - 5.2e-46 156.6 0.0 5.2e-46 156.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EWM26104.1 - 4.7e-24 84.9 0.0 2e-23 82.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EWM26104.1 - 6.7e-19 67.9 0.7 1.3e-18 66.9 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EWM26104.1 - 2.3e-05 24.5 0.8 0.0001 22.4 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EWM26104.1 - 0.026 13.7 0.0 0.026 13.7 0.0 2.3 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase PepSY_TM_like_2 PF16357.5 EWM26104.1 - 0.15 12.1 1.0 0.3 11.0 1.0 1.4 1 0 0 1 1 1 0 Putative PepSY_TM-like AAA_22 PF13401.6 EWM26104.1 - 0.86 9.9 5.2 0.17 12.1 0.2 2.4 2 1 0 2 2 2 0 AAA domain NPR3 PF03666.13 EWM26104.1 - 3.8 6.2 11.1 18 4.0 0.0 2.3 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 PALP PF00291.25 EWM26105.1 - 1.1e-64 218.7 0.0 1.5e-64 218.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 EWM26105.1 - 4.1e-08 33.5 0.1 9.5e-05 22.8 0.0 4.0 3 1 0 3 3 3 2 CBS domain RmlD_sub_bind PF04321.17 EWM26108.1 - 1.4e-46 158.9 0.0 1.2e-42 146.0 0.0 2.0 2 0 0 2 2 2 2 RmlD substrate binding domain Epimerase PF01370.21 EWM26108.1 - 2.4e-21 76.3 0.0 3.3e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EWM26108.1 - 0.00056 19.4 0.0 0.00074 19.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EWM26108.1 - 0.0076 15.4 0.2 0.23 10.6 0.2 2.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EWM26108.1 - 0.015 14.4 0.1 0.26 10.4 0.0 2.5 2 1 0 2 2 2 0 Male sterility protein Methyltr_RsmB-F PF01189.17 EWM26109.1 - 3.3e-29 102.0 0.0 1e-26 93.8 0.0 3.2 3 1 0 3 3 3 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 EWM26109.1 - 0.065 13.3 0.0 0.16 12.1 0.0 1.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase AMP-binding PF00501.28 EWM26110.1 - 1e-79 268.1 0.1 1.3e-79 267.8 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ELM2 PF01448.24 EWM26111.1 - 0.0076 17.0 0.0 0.017 15.9 0.0 1.6 1 0 0 1 1 1 1 ELM2 domain PDZ_6 PF17820.1 EWM26112.1 - 0.00038 20.2 0.1 0.00092 19.0 0.1 1.7 1 0 0 1 1 1 1 PDZ domain WD40 PF00400.32 EWM26112.1 - 0.0069 17.2 0.5 0.45 11.5 0.2 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat zf-RING_11 PF17123.5 EWM26112.1 - 0.039 13.7 0.2 0.039 13.7 0.2 1.9 2 0 0 2 2 2 0 RING-like zinc finger ANAPC4_WD40 PF12894.7 EWM26112.1 - 0.089 13.1 0.0 1.8 8.9 0.0 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain IQ PF00612.27 EWM26112.1 - 0.093 12.6 1.6 0.32 10.9 1.6 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif zf-rbx1 PF12678.7 EWM26112.1 - 0.23 11.8 1.2 0.66 10.3 1.2 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3H2C3 PF17122.5 EWM26112.1 - 1.2 9.2 5.6 0.13 12.3 0.9 1.8 2 0 0 2 2 2 0 Zinc-finger PGK PF00162.19 EWM26113.1 - 7.1e-161 535.4 2.9 7.4e-159 528.7 2.2 2.0 2 0 0 2 2 2 2 Phosphoglycerate kinase TMP-TENI PF02581.17 EWM26113.1 - 0.0034 16.7 0.2 0.031 13.6 0.0 2.1 2 0 0 2 2 2 1 Thiamine monophosphate synthase PrpR_N PF06506.11 EWM26113.1 - 0.033 13.8 1.3 0.87 9.1 0.1 3.4 3 2 1 4 4 4 0 Propionate catabolism activator PGK PF00162.19 EWM26114.1 - 4.9e-73 246.2 0.2 2.9e-64 217.4 0.0 3.0 3 0 0 3 3 3 3 Phosphoglycerate kinase WD40 PF00400.32 EWM26115.1 - 9.2e-05 23.1 1.0 0.00057 20.6 0.0 3.0 3 0 0 3 3 3 1 WD domain, G-beta repeat PQQ_3 PF13570.6 EWM26115.1 - 2.2 8.9 5.0 20 5.8 0.1 3.9 4 0 0 4 4 4 0 PQQ-like domain ATP-synt_10 PF05176.14 EWM26116.1 - 4e-35 121.3 0.0 5.2e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 ATP10 protein Mito_carr PF00153.27 EWM26117.1 - 7e-39 131.7 0.5 8.1e-12 44.9 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein Methyltransf_11 PF08241.12 EWM26119.1 - 2.7e-16 60.0 0.0 5.5e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM26119.1 - 3.8e-13 50.0 0.0 7.9e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EWM26119.1 - 2.2e-08 33.7 0.0 3.3e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EWM26119.1 - 7.7e-08 32.3 0.0 1.6e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EWM26119.1 - 1.6e-05 25.6 0.0 3e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM26119.1 - 0.0027 17.5 0.0 0.032 14.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EWM26119.1 - 0.051 13.4 0.0 0.12 12.2 0.0 1.6 1 1 0 1 1 1 0 Hypothetical methyltransferase RrnaAD PF00398.20 EWM26119.1 - 0.14 11.2 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltrn_RNA_3 PF02598.17 EWM26120.1 - 1.4e-101 339.8 0.0 1.7e-101 339.5 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.19 EWM26120.1 - 0.12 12.5 0.0 5.2 7.2 0.0 2.4 2 0 0 2 2 2 0 SpoU rRNA Methylase family Prenyltrans PF00432.21 EWM26121.1 - 9.7e-42 140.4 16.2 1.8e-09 37.1 0.5 5.4 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans PF00432.21 EWM26122.1 - 4.1e-42 141.6 16.2 1.5e-09 37.4 0.5 5.3 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Cpn60_TCP1 PF00118.24 EWM26124.1 - 4.1e-78 263.2 10.1 2.1e-77 260.9 10.1 1.8 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Dioxygenase_N PF04444.14 EWM26124.1 - 0.05 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Catechol dioxygenase N terminus ClpS PF02617.17 EWM26126.1 - 8.2e-14 51.2 0.0 1.7e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS MENTAL PF10457.9 EWM26126.1 - 0.089 12.6 0.1 0.23 11.2 0.0 1.6 2 0 0 2 2 2 0 Cholesterol-capturing domain Kinesin PF00225.23 EWM26127.1 - 3.5e-93 312.2 0.0 8.3e-93 310.9 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EWM26127.1 - 7.1e-17 61.7 0.1 6.6e-16 58.6 0.1 2.3 1 1 0 1 1 1 1 Microtubule binding PH PF00169.29 EWM26127.1 - 1.5e-12 48.0 0.0 3.3e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_6 PF15406.6 EWM26127.1 - 0.023 15.0 0.0 0.078 13.3 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain PPL5 PF18168.1 EWM26127.1 - 1.3 8.3 7.3 2.2 7.5 7.3 1.3 1 0 0 1 1 1 0 Prim-pol family 5 BUD22 PF09073.10 EWM26127.1 - 1.7 7.9 22.4 2.8 7.2 22.4 1.3 1 0 0 1 1 1 0 BUD22 NPR3 PF03666.13 EWM26127.1 - 7.6 5.2 6.2 11 4.6 6.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3395 PF11875.8 EWM26128.1 - 6.8e-29 100.8 0.0 1.2e-28 100.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 EWM26128.1 - 9e-17 61.0 0.3 1.6e-16 60.2 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain LRR_8 PF13855.6 EWM26129.1 - 5.9e-13 48.4 8.7 1.4e-12 47.1 7.1 2.1 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 EWM26129.1 - 6.5e-13 48.6 15.7 4.3e-08 33.3 4.5 3.0 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EWM26129.1 - 0.0026 18.1 10.0 0.16 12.6 1.9 3.9 3 2 0 3 3 3 2 Leucine Rich Repeat LRR_9 PF14580.6 EWM26129.1 - 0.045 13.2 1.7 0.083 12.4 0.6 1.8 1 1 1 2 2 2 0 Leucine-rich repeat LRR_6 PF13516.6 EWM26129.1 - 0.91 9.7 9.6 1.6 8.9 0.5 4.0 4 1 1 5 5 5 0 Leucine Rich repeat EF-hand_1 PF00036.32 EWM26131.1 - 3.3e-33 110.8 9.9 3.7e-07 29.2 0.3 7.6 7 0 0 7 7 7 6 EF hand EF-hand_7 PF13499.6 EWM26131.1 - 1.4e-30 105.6 9.0 7.4e-11 42.3 1.2 5.1 4 1 0 4 4 4 3 EF-hand domain pair Metallophos PF00149.28 EWM26131.1 - 5.1e-26 92.4 0.0 8.1e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_6 PF13405.6 EWM26131.1 - 3.7e-24 82.6 9.8 3.8e-05 23.3 0.2 7.4 7 0 0 7 7 7 5 EF-hand domain EF-hand_5 PF13202.6 EWM26131.1 - 3.1e-20 70.7 12.3 0.00013 21.3 0.3 6.6 6 0 0 6 6 6 4 EF hand EF-hand_8 PF13833.6 EWM26131.1 - 3.9e-20 71.4 10.9 1.8e-07 30.9 0.6 5.7 3 2 2 5 5 5 5 EF-hand domain pair CAP_GLY PF01302.25 EWM26131.1 - 5.6e-17 61.5 0.0 1.9e-16 59.9 0.0 1.9 1 0 0 1 1 1 1 CAP-Gly domain PPP5 PF08321.12 EWM26131.1 - 5.4e-08 33.0 0.0 1.3e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region SPARC_Ca_bdg PF10591.9 EWM26131.1 - 2.1e-07 31.3 0.2 0.31 11.4 0.0 4.1 4 0 0 4 4 4 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 EWM26131.1 - 1.3e-06 29.2 0.1 0.028 15.3 0.0 4.9 5 0 0 5 5 5 1 EF-hand domain EF-hand_4 PF12763.7 EWM26131.1 - 2.6e-05 24.1 5.9 3.5 7.6 0.1 5.4 4 2 2 6 6 6 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EWM26131.1 - 0.0002 21.6 0.2 0.055 13.8 0.1 3.9 4 0 0 4 4 4 1 EF-hand domain Dockerin_1 PF00404.18 EWM26131.1 - 0.0055 16.9 0.0 4 7.7 0.0 3.6 4 0 0 4 4 4 1 Dockerin type I domain TerB PF05099.13 EWM26131.1 - 0.035 14.1 0.2 2 8.4 0.0 3.4 3 1 0 3 3 3 0 Tellurite resistance protein TerB Mpv17_PMP22 PF04117.12 EWM26132.1 - 2.5e-21 75.7 0.1 4.3e-21 74.9 0.1 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Mpv17_PMP22 PF04117.12 EWM26133.1 - 2.5e-21 75.7 0.1 4.3e-21 74.9 0.1 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Ribosomal_L11_N PF03946.14 EWM26134.1 - 1.7e-21 75.8 0.7 2.7e-21 75.2 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EWM26134.1 - 2.5e-17 63.2 0.6 5.6e-17 62.0 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain CorC_HlyC PF03471.17 EWM26134.1 - 0.052 13.6 0.0 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 Transporter associated domain CSD2 PF17876.1 EWM26134.1 - 0.14 12.3 0.1 0.56 10.4 0.0 2.0 2 0 0 2 2 2 0 Cold shock domain AAA_18 PF13238.6 EWM26135.1 - 5.7e-07 30.1 0.0 1.3e-06 29.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 EWM26135.1 - 4.6e-06 26.5 0.0 6.3e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family KTI12 PF08433.10 EWM26135.1 - 2.9e-05 23.7 0.0 4.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 EWM26135.1 - 6.4e-05 23.1 0.0 0.0012 19.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 EWM26135.1 - 0.00055 19.0 0.0 0.001 18.1 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 EWM26135.1 - 0.0018 17.6 0.0 0.022 14.0 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin APS_kinase PF01583.20 EWM26135.1 - 0.0033 17.3 0.0 0.02 14.8 0.0 2.0 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_16 PF13191.6 EWM26135.1 - 0.015 15.6 0.0 0.026 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.17 EWM26135.1 - 0.017 14.9 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.6 EWM26135.1 - 0.018 15.5 0.0 1 9.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EWM26135.1 - 0.027 14.7 0.0 0.055 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ADK PF00406.22 EWM26135.1 - 0.055 13.6 0.0 8.5 6.5 0.0 2.2 2 0 0 2 2 2 0 Adenylate kinase NTPase_1 PF03266.15 EWM26135.1 - 0.059 13.3 0.1 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.22 EWM26135.1 - 0.12 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Cytidylate_kin PF02224.18 EWM26135.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.6 2 0 0 2 2 2 0 Cytidylate kinase AAA_22 PF13401.6 EWM26135.1 - 0.19 12.0 0.0 0.48 10.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain IGPS PF00218.21 EWM26136.1 - 2.1e-75 253.2 0.1 3.5e-75 252.4 0.1 1.4 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 EWM26136.1 - 3.1e-37 128.2 0.2 1e-32 113.5 0.1 3.0 2 1 0 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase QRPTase_C PF01729.19 EWM26136.1 - 0.067 13.0 0.0 0.41 10.4 0.0 2.2 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, C-terminal domain AT_hook PF02178.19 EWM26137.1 - 3.7 7.8 5.5 15 5.9 5.5 2.1 1 0 0 1 1 1 0 AT hook motif PPR PF01535.20 EWM26138.1 - 1.2e-42 141.2 14.3 0.00067 19.7 0.2 13.7 14 0 0 14 14 14 9 PPR repeat PPR_2 PF13041.6 EWM26138.1 - 1.2e-39 134.3 0.0 6.1e-07 29.5 0.0 11.2 10 1 1 11 11 11 7 PPR repeat family PPR_1 PF12854.7 EWM26138.1 - 1.3e-23 82.3 9.0 9.4e-06 25.2 0.0 9.9 11 0 0 11 11 11 4 PPR repeat PPR_3 PF13812.6 EWM26138.1 - 4.3e-12 45.9 0.0 0.056 13.5 0.0 7.3 6 2 1 8 8 8 2 Pentatricopeptide repeat domain PPR_long PF17177.4 EWM26138.1 - 6.2e-10 38.8 0.1 0.024 14.0 0.0 5.0 4 2 1 5 5 5 3 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 EWM26138.1 - 3.5e-07 30.6 18.6 0.046 14.2 0.0 7.7 8 1 1 9 9 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 EWM26138.1 - 2.9e-05 24.5 35.6 2.9 9.0 0.7 12.1 13 1 1 14 14 14 1 Tetratricopeptide repeat BTAD PF03704.17 EWM26138.1 - 0.00031 21.2 24.4 1.2 9.6 0.1 7.2 7 1 0 7 7 7 3 Bacterial transcriptional activator domain TPR_12 PF13424.6 EWM26138.1 - 0.0011 19.2 11.9 2 8.8 0.4 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat SPO22 PF08631.10 EWM26138.1 - 0.0015 18.1 0.0 0.0039 16.7 0.0 1.6 1 0 0 1 1 1 1 Meiosis protein SPO22/ZIP4 like TPR_4 PF07721.14 EWM26138.1 - 0.0056 17.2 51.8 0.9 10.3 1.5 12.0 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_7 PF13176.6 EWM26138.1 - 0.025 14.6 16.1 89 3.5 0.0 9.8 13 0 0 13 13 11 0 Tetratricopeptide repeat Sec16_C PF12931.7 EWM26138.1 - 0.099 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 HEAT_PBS PF03130.16 EWM26138.1 - 0.19 12.5 6.3 9.5 7.2 0.0 5.6 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat TPR_10 PF13374.6 EWM26138.1 - 5.2 7.1 16.5 18 5.4 0.1 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat UbiA PF01040.18 EWM26139.1 - 4.1e-47 160.6 14.7 5.7e-47 160.1 14.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF5368 PF17336.2 EWM26139.1 - 0.12 12.6 0.2 0.33 11.1 0.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5368) SID-1_RNA_chan PF13965.6 EWM26139.1 - 0.16 10.4 0.0 0.23 9.8 0.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Pkinase PF00069.25 EWM26141.1 - 2.9e-65 220.3 0.0 3.8e-65 219.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM26141.1 - 1.2e-18 67.4 0.0 1.7e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EWM26141.1 - 2.2e-07 31.0 0.0 0.00018 21.5 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Glyco_trans_1_4 PF13692.6 EWM26141.1 - 2e-06 28.3 0.0 4.6e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EWM26141.1 - 5.5e-06 26.0 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EWM26141.1 - 1.3e-05 25.7 0.1 3.2e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 EWM26141.1 - 0.00012 22.1 0.3 0.00025 21.1 0.3 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Pkinase_fungal PF17667.1 EWM26141.1 - 0.0088 14.9 0.0 0.017 13.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 EWM26141.1 - 0.092 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase FGase PF05013.12 EWM26142.1 - 0.13 12.4 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 N-formylglutamate amidohydrolase Coatomer_WDAD PF04053.14 EWM26143.1 - 8.8e-117 390.9 0.0 1.4e-116 390.2 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 EWM26143.1 - 7.2e-109 364.2 0.0 1.4e-108 363.3 0.0 1.3 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 EWM26143.1 - 4.6e-43 144.4 15.6 7e-08 33.0 0.1 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM26143.1 - 2.2e-08 34.3 1.7 0.0021 18.3 0.0 5.5 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EWM26143.1 - 0.065 13.1 0.1 3.6 7.4 0.0 3.0 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A zf-LSD1 PF06943.12 EWM26143.1 - 0.57 10.1 8.3 0.074 12.9 3.9 1.8 2 0 0 2 2 2 0 LSD1 zinc finger Nup160 PF11715.8 EWM26143.1 - 1.8 7.1 7.1 2.4 6.7 0.1 2.9 2 1 1 3 3 3 0 Nucleoporin Nup120/160 RNA_pol PF00940.19 EWM26144.1 - 1.3e-154 515.0 0.0 3.2e-154 513.8 0.0 1.6 1 1 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 EWM26144.1 - 1.6e-45 156.0 0.0 1.6e-21 77.1 0.0 2.7 3 0 0 3 3 3 2 DNA-directed RNA polymerase N-terminal zf-MIZ PF02891.20 EWM26145.1 - 6.6e-18 64.2 0.2 6.6e-18 64.2 0.2 1.9 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger PINIT PF14324.6 EWM26145.1 - 2.1e-06 28.1 0.0 3.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 PINIT domain SAP PF02037.27 EWM26145.1 - 0.00043 20.0 0.0 0.00083 19.1 0.0 1.5 1 0 0 1 1 1 1 SAP domain PHD_2 PF13831.6 EWM26145.1 - 0.0014 18.2 1.9 0.0014 18.2 1.9 2.2 2 0 0 2 2 2 1 PHD-finger zf-Nse PF11789.8 EWM26145.1 - 0.0028 17.4 0.0 0.0077 16.0 0.0 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.29 EWM26145.1 - 0.012 15.5 13.4 0.016 15.1 7.1 2.5 2 0 0 2 2 2 0 PHD-finger Pkinase PF00069.25 EWM26146.1 - 5.5e-14 52.2 0.0 8e-12 45.1 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EWM26146.1 - 2.5e-10 40.1 0.0 5.4e-10 39.0 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase HEAT PF02985.22 EWM26146.1 - 3.4e-07 30.0 3.6 1.8 9.1 0.0 5.6 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 EWM26146.1 - 0.0018 18.6 0.0 0.01 16.2 0.0 2.4 1 1 0 1 1 1 1 HEAT repeats Cnd1 PF12717.7 EWM26146.1 - 0.14 12.2 0.1 0.53 10.3 0.0 2.0 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EWM26146.1 - 0.19 11.2 0.1 5.9 6.4 0.0 2.2 1 1 1 2 2 2 0 CLASP N terminal ILVD_EDD PF00920.21 EWM26147.1 - 7.8e-221 734.2 0.4 9.1e-221 733.9 0.4 1.0 1 0 0 1 1 1 1 Dehydratase family FeoA PF04023.14 EWM26147.1 - 0.033 14.4 0.1 1.4 9.2 0.0 2.8 2 0 0 2 2 2 0 FeoA domain zf-C2HC5 PF06221.13 EWM26148.1 - 2e-09 37.3 8.9 3.9e-09 36.4 8.9 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Cir_N PF10197.9 EWM26148.1 - 4.7 7.5 16.3 3.2 8.0 8.9 3.2 2 0 0 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR zf-C2HC5 PF06221.13 EWM26149.1 - 2e-09 37.3 8.9 3.9e-09 36.4 8.9 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Cir_N PF10197.9 EWM26149.1 - 4.7 7.5 16.3 3.2 8.0 8.9 3.2 2 0 0 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR SPX PF03105.19 EWM26150.1 - 6.5e-21 75.7 9.4 6.4e-11 42.8 0.2 4.0 2 1 2 4 4 4 4 SPX domain GBP PF02263.19 EWM26151.1 - 6.6e-50 169.8 0.3 4.1e-49 167.2 0.3 1.9 1 1 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 EWM26151.1 - 1.1e-06 28.2 0.3 1.9e-06 27.5 0.3 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain ETF_QO PF05187.13 EWM26151.1 - 0.19 11.9 0.0 0.47 10.6 0.0 1.6 1 0 0 1 1 1 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S HEAT PF02985.22 EWM26152.1 - 1.1e-31 106.2 43.2 0.019 15.2 0.3 14.7 15 0 0 15 15 15 11 HEAT repeat HEAT_2 PF13646.6 EWM26152.1 - 6.3e-30 103.4 24.4 1.7e-10 41.1 0.1 7.0 2 2 4 7 7 7 7 HEAT repeats Vac14_Fab1_bd PF12755.7 EWM26152.1 - 5e-07 30.2 0.0 0.39 11.4 0.0 5.5 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EWM26152.1 - 6.3e-06 26.6 24.8 3.6 8.2 0.1 9.6 9 3 2 11 11 11 3 HEAT-like repeat CLASP_N PF12348.8 EWM26152.1 - 1.8e-05 24.4 0.0 0.29 10.7 0.0 5.1 1 1 5 6 6 6 1 CLASP N terminal Adaptin_N PF01602.20 EWM26152.1 - 2.3e-05 23.2 0.3 0.00036 19.2 0.1 2.8 1 1 1 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 EWM26152.1 - 3.1e-05 24.1 6.4 0.14 12.2 0.3 5.4 3 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 EWM26152.1 - 7.4e-05 22.9 2.0 0.057 13.6 0.0 3.8 4 2 0 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 EWM26152.1 - 0.26 11.4 11.2 12 6.1 0.1 6.2 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat Proteasome PF00227.26 EWM26153.1 - 6.3e-61 205.2 0.3 8.4e-61 204.8 0.3 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EWM26153.1 - 2.2e-14 52.8 0.1 4.8e-14 51.7 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RCDG1 PF15725.5 EWM26154.1 - 1.4 9.4 5.4 20 5.7 0.2 2.5 2 1 0 2 2 2 0 Renal cancer differentiation gene 1 protein YIF1 PF03878.15 EWM26155.1 - 3.8e-53 180.5 3.6 5.6e-53 179.9 3.6 1.2 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 EWM26155.1 - 0.0015 18.3 7.9 0.0025 17.6 6.2 2.0 1 1 1 2 2 2 1 Yip1 domain AAA_16 PF13191.6 EWM26156.1 - 0.00062 20.2 0.1 0.0042 17.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Glyco_hydro_9 PF00759.19 EWM26157.1 - 1.3e-128 430.0 10.9 1.5e-128 429.8 10.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Glyco_hydro_88 PF07470.13 EWM26157.1 - 0.0034 16.5 1.6 0.0081 15.3 1.2 1.7 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 O-FucT PF10250.9 EWM26159.1 - 0.002 17.9 0.1 0.011 15.4 0.0 2.1 2 1 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase Asn_synthase PF00733.21 EWM26160.1 - 3.2e-14 53.4 0.4 3.7e-09 36.7 0.1 3.2 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 EWM26160.1 - 6e-06 26.2 0.0 0.00016 21.5 0.0 2.4 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EWM26160.1 - 0.06 13.5 0.0 0.42 10.8 0.0 2.4 3 1 0 3 3 3 0 Glutamine amidotransferase domain Methyltransf_11 PF08241.12 EWM26161.1 - 1.4e-07 32.1 0.0 4.2e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EWM26161.1 - 2.6e-07 30.6 0.0 6.7e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EWM26161.1 - 2.4e-06 28.2 0.0 5.8e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM26161.1 - 0.00019 21.2 0.0 0.00041 20.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM26161.1 - 0.00066 20.3 0.0 0.0024 18.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EWM26161.1 - 0.0022 17.6 0.0 0.022 14.4 0.0 2.1 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW E1-N PF14463.6 EWM26161.1 - 0.056 13.2 0.3 0.12 12.2 0.3 1.5 1 0 0 1 1 1 0 E1 N-terminal domain GDH_N PF12466.8 EWM26161.1 - 0.062 13.5 0.1 0.27 11.4 0.0 2.1 2 0 0 2 2 2 0 Glutamate dehydrogenase N terminal Ubie_methyltran PF01209.18 EWM26161.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DnaJ PF00226.31 EWM26163.1 - 3e-17 62.5 0.5 2.2e-16 59.7 0.1 2.5 2 0 0 2 2 2 1 DnaJ domain HsbA PF12296.8 EWM26163.1 - 0.019 15.4 2.3 0.019 15.4 2.3 2.6 2 0 0 2 2 2 0 Hydrophobic surface binding protein A DUF948 PF06103.11 EWM26163.1 - 0.85 9.9 3.7 2.8 8.2 0.3 2.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4336 PF14234.6 EWM26165.1 - 3.4e-22 79.1 0.5 9.1e-18 64.5 0.1 2.8 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) stn_TNFRSF12A PF12191.8 EWM26165.1 - 0.066 13.4 1.0 0.19 11.9 0.8 1.8 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain UQ_con PF00179.26 EWM26166.1 - 0.00031 20.4 0.0 0.00052 19.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EWM26166.1 - 0.055 13.8 0.0 0.081 13.2 0.0 1.4 1 0 0 1 1 1 0 RWD domain VPS13_C PF16909.5 EWM26167.1 - 2e-10 40.7 0.0 4.1e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal FKBP_C PF00254.28 EWM26168.1 - 3.5e-13 49.7 0.0 6.6e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase CS PF04969.16 EWM26168.1 - 7.6e-11 42.9 0.1 1.2e-10 42.2 0.1 1.4 1 0 0 1 1 1 1 CS domain FKBP_N_2 PF18023.1 EWM26168.1 - 0.0048 17.0 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 BDBT FKBP like N-terminal VRR_NUC PF08774.11 EWM26169.1 - 7.7e-22 77.4 0.0 9.6e-20 70.7 0.0 3.3 3 0 0 3 3 3 2 VRR-NUC domain RRM_1 PF00076.22 EWM26171.1 - 3.5e-18 65.2 0.1 5.5e-18 64.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.8 EWM26171.1 - 2.7e-09 37.5 0.2 4.4e-09 36.8 0.2 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G Fucokinase PF07959.12 EWM26172.1 - 1.3e-64 218.6 0.0 1.9e-64 218.1 0.0 1.3 1 0 0 1 1 1 1 L-fucokinase GHMP_kinases_C PF08544.13 EWM26172.1 - 6.5e-09 36.0 0.0 3.6e-08 33.7 0.0 2.4 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 EWM26172.1 - 1.3e-06 28.5 3.5 1.4e-06 28.4 0.9 2.6 3 0 0 3 3 3 1 GHMP kinases N terminal domain AAA_22 PF13401.6 EWM26173.1 - 1.9e-06 28.2 0.1 5.5e-05 23.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EWM26173.1 - 0.0008 19.8 0.2 0.0008 19.8 0.2 3.2 4 1 0 4 4 4 1 AAA ATPase domain AAA PF00004.29 EWM26173.1 - 0.027 14.9 0.1 7.6 7.0 0.1 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CDC45 PF02724.14 EWM26173.1 - 0.044 12.1 20.2 0.075 11.3 20.2 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF5331 PF17265.2 EWM26173.1 - 0.14 11.9 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5331) Nop14 PF04147.12 EWM26173.1 - 1.8 6.7 23.9 2.9 6.0 23.9 1.2 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.11 EWM26173.1 - 9.6 4.1 9.2 22 3.0 9.2 1.6 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SHQ1 PF04925.15 EWM26175.1 - 4.8e-09 36.0 0.0 6.1e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 SHQ1 protein CDC45 PF02724.14 EWM26175.1 - 0.0007 18.0 15.4 0.00082 17.8 15.4 1.0 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 EWM26175.1 - 0.003 15.9 20.7 0.0033 15.8 20.7 1.0 1 0 0 1 1 1 1 Nop14-like family RRN3 PF05327.11 EWM26175.1 - 0.0059 15.2 12.9 0.0061 15.2 12.9 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 CNDH2_C PF16858.5 EWM26175.1 - 0.0064 16.4 5.0 0.007 16.3 5.0 1.1 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term SDA1 PF05285.12 EWM26175.1 - 0.0093 15.4 21.9 0.01 15.3 21.9 1.1 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 EWM26175.1 - 0.019 14.3 14.7 0.02 14.2 14.7 1.1 1 0 0 1 1 1 0 BUD22 DUF2457 PF10446.9 EWM26175.1 - 0.027 13.6 34.3 0.034 13.3 34.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Mpp10 PF04006.12 EWM26175.1 - 0.027 12.9 16.0 0.03 12.8 16.0 1.0 1 0 0 1 1 1 0 Mpp10 protein Vfa1 PF08432.10 EWM26175.1 - 0.032 14.6 5.9 0.04 14.3 5.9 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 YL1 PF05764.13 EWM26175.1 - 0.036 14.2 20.7 0.04 14.0 20.7 1.1 1 0 0 1 1 1 0 YL1 nuclear protein DNA_pol_phi PF04931.13 EWM26175.1 - 0.069 11.3 33.2 0.082 11.0 33.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi Utp14 PF04615.13 EWM26175.1 - 0.084 11.4 15.9 0.099 11.2 15.9 1.1 1 0 0 1 1 1 0 Utp14 protein NOA36 PF06524.12 EWM26175.1 - 0.091 12.1 28.3 0.12 11.6 28.3 1.2 1 0 0 1 1 1 0 NOA36 protein DUF913 PF06025.12 EWM26175.1 - 0.12 11.3 1.0 0.13 11.3 1.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CobT PF06213.12 EWM26175.1 - 0.14 11.5 21.8 0.18 11.1 21.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SAPS PF04499.15 EWM26175.1 - 0.2 10.4 3.8 0.22 10.3 3.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RNA_pol_Rpc4 PF05132.14 EWM26175.1 - 0.23 11.9 1.2 0.27 11.7 1.2 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Tim54 PF11711.8 EWM26175.1 - 0.36 9.6 3.4 0.44 9.3 3.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CPSF100_C PF13299.6 EWM26175.1 - 0.41 10.8 3.0 0.55 10.4 3.0 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Apt1 PF10351.9 EWM26175.1 - 0.43 9.4 2.6 0.48 9.2 2.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC27 PF09507.10 EWM26175.1 - 0.74 9.1 11.6 0.88 8.9 11.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Cnd2 PF05786.14 EWM26175.1 - 1.1 7.9 14.2 1.2 7.7 14.2 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 DUF5542 PF17696.1 EWM26175.1 - 1.6 8.9 5.7 1.2 9.3 2.2 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5542) RPN2_C PF18004.1 EWM26175.1 - 1.7 8.5 7.5 2.3 8.1 7.5 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Osteopontin PF00865.18 EWM26175.1 - 2.9 7.3 27.2 3.4 7.1 27.2 1.1 1 0 0 1 1 1 0 Osteopontin GEN1_C PF18380.1 EWM26175.1 - 2.9 8.8 12.0 5 8.1 12.0 1.4 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain TFB6 PF17110.5 EWM26175.1 - 3.4 7.4 11.3 5.9 6.6 11.3 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH polyprenyl_synt PF00348.17 EWM26176.1 - 1.3e-68 230.8 0.3 2.2e-68 230.1 0.3 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 EWM26176.1 - 0.00013 21.6 0.1 0.00026 20.7 0.1 1.4 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 zf-RING_6 PF14835.6 EWM26177.1 - 4.3e-10 39.3 2.7 9.3e-10 38.3 2.7 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.6 EWM26177.1 - 1.3e-07 31.3 13.7 1.3e-07 31.3 13.7 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EWM26177.1 - 1.1e-06 28.7 10.9 2.4e-06 27.6 10.9 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EWM26177.1 - 1.6e-06 27.9 9.2 3.8e-06 26.7 9.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EWM26177.1 - 3.1e-06 27.1 10.3 8.1e-06 25.8 10.3 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EWM26177.1 - 5.1e-06 26.3 12.7 1.2e-05 25.1 12.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 EWM26177.1 - 8e-06 25.9 5.1 1.8e-05 24.8 5.1 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 U-box PF04564.15 EWM26177.1 - 9.4e-06 25.7 0.0 3.2e-05 24.0 0.0 2.0 1 0 0 1 1 1 1 U-box domain Prok-RING_4 PF14447.6 EWM26177.1 - 0.00011 22.0 12.1 0.00031 20.5 12.1 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EWM26177.1 - 0.00051 20.3 12.8 0.0017 18.6 12.8 2.0 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EWM26177.1 - 0.00098 19.0 12.2 0.0024 17.8 12.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 EWM26177.1 - 0.01 15.6 2.4 0.031 14.1 2.4 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 EWM26177.1 - 0.096 13.0 8.6 0.29 11.4 8.6 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain DUF1272 PF06906.11 EWM26177.1 - 0.11 12.6 5.7 0.28 11.3 5.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zinc-ribbons_6 PF07191.12 EWM26177.1 - 0.82 9.7 6.8 2.4 8.2 6.8 1.8 1 0 0 1 1 1 0 zinc-ribbons DZR PF12773.7 EWM26177.1 - 1 9.4 6.9 3.2 7.8 6.9 1.8 1 0 0 1 1 1 0 Double zinc ribbon CRAL_TRIO PF00650.20 EWM26178.1 - 1.5e-26 93.0 0.0 2.1e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain Amino_oxidase PF01593.24 EWM26179.1 - 3.6e-42 145.2 0.5 6.1e-30 104.9 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EWM26179.1 - 4.6e-15 55.6 0.3 1.6e-14 53.9 0.1 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EWM26179.1 - 4.5e-07 29.3 5.6 8.7e-07 28.4 5.6 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EWM26179.1 - 6.3e-06 25.6 1.2 1.2e-05 24.7 1.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EWM26179.1 - 7.5e-06 24.9 2.4 1.1e-05 24.3 2.4 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 EWM26179.1 - 1.4e-05 24.9 0.3 3e-05 23.8 0.3 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EWM26179.1 - 3.1e-05 24.5 1.3 6.3e-05 23.5 1.3 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EWM26179.1 - 0.00013 21.3 1.7 0.00021 20.7 1.7 1.2 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 EWM26179.1 - 0.00019 20.8 0.8 0.00039 19.8 0.8 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 EWM26179.1 - 0.00023 20.6 5.1 0.0004 19.9 5.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EWM26179.1 - 0.00045 19.5 0.6 0.00075 18.8 0.6 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 EWM26179.1 - 0.0084 15.2 1.0 0.0084 15.2 1.0 1.9 2 1 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.22 EWM26179.1 - 0.013 14.6 2.8 0.02 14.0 2.8 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A TrkA_N PF02254.18 EWM26179.1 - 0.034 14.4 0.5 0.085 13.1 0.5 1.7 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 EWM26179.1 - 0.052 13.1 0.7 0.089 12.4 0.7 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FMO-like PF00743.19 EWM26179.1 - 0.056 11.9 0.1 0.078 11.4 0.1 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like NAD_binding_7 PF13241.6 EWM26179.1 - 0.094 13.2 0.2 0.26 11.8 0.2 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 EWM26179.1 - 0.13 12.3 0.3 0.25 11.4 0.3 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 EWM26179.1 - 0.16 11.9 1.5 0.59 10.1 0.2 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EWM26179.1 - 0.17 11.1 0.9 0.27 10.5 0.9 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EWM26179.1 - 0.63 9.9 2.3 1.2 9.0 2.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 EWM26179.1 - 2 7.2 3.5 3 6.6 3.5 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Ribosomal_L6 PF00347.23 EWM26180.1 - 1.1e-27 96.5 0.8 5.6e-14 52.6 0.1 3.0 2 1 0 2 2 2 2 Ribosomal protein L6 CENP-W PF15510.6 EWM26180.1 - 0.025 14.8 0.1 2.7 8.3 0.1 2.3 2 0 0 2 2 2 0 CENP-W protein ABC_membrane PF00664.23 EWM26181.1 - 1.6e-59 201.8 12.4 1.1e-39 136.8 5.4 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EWM26181.1 - 1.5e-48 164.8 0.0 3.7e-28 98.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EWM26181.1 - 6.7e-08 32.2 0.1 0.66 9.4 0.0 4.0 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EWM26181.1 - 2.3e-06 27.3 0.1 0.069 12.9 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EWM26181.1 - 5.6e-06 26.4 0.3 0.25 11.4 0.0 3.5 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_16 PF13191.6 EWM26181.1 - 6.5e-06 26.6 0.1 0.013 15.9 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 EWM26181.1 - 3.2e-05 24.5 0.8 0.28 11.6 0.1 2.2 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 EWM26181.1 - 9.8e-05 22.3 0.0 2.4 7.9 0.0 3.7 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EWM26181.1 - 0.00011 22.0 0.0 0.23 11.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain NACHT PF05729.12 EWM26181.1 - 0.00016 21.6 0.3 0.075 12.9 0.0 2.4 2 0 0 2 2 2 1 NACHT domain DUF87 PF01935.17 EWM26181.1 - 0.00016 21.8 3.0 0.07 13.2 0.7 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain NB-ARC PF00931.22 EWM26181.1 - 0.00046 19.4 0.5 0.22 10.7 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain cobW PF02492.19 EWM26181.1 - 0.0025 17.4 1.0 1.6 8.3 0.1 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 EWM26181.1 - 0.003 16.7 0.0 0.79 8.7 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.6 EWM26181.1 - 0.003 17.8 0.9 1.7 8.9 0.2 3.4 3 1 0 3 3 3 1 AAA domain SbcCD_C PF13558.6 EWM26181.1 - 0.0078 16.4 0.1 0.29 11.4 0.0 2.7 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 EWM26181.1 - 0.01 16.4 0.1 5.2 7.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EWM26181.1 - 0.013 15.4 0.0 7.4 6.5 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase MobB PF03205.14 EWM26181.1 - 0.018 15.0 0.4 4.9 7.1 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 EWM26181.1 - 0.032 14.4 0.1 9.3 6.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 EWM26181.1 - 0.036 13.0 0.2 1.8 7.4 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 EWM26181.1 - 0.041 13.8 0.2 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.6 EWM26181.1 - 0.045 13.5 1.0 8.1 6.1 0.1 2.6 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EWM26181.1 - 0.051 13.6 2.2 0.89 9.6 0.1 2.9 3 0 0 3 3 3 0 Dynamin family ATPase_2 PF01637.18 EWM26181.1 - 0.056 13.3 0.2 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 EWM26181.1 - 0.057 12.7 0.1 1.4 8.1 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain TsaE PF02367.17 EWM26181.1 - 0.058 13.4 0.0 16 5.5 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 EWM26181.1 - 0.13 11.8 0.3 6.7 6.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 EWM26181.1 - 0.17 11.2 0.1 12 5.2 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family CoaE PF01121.20 EWM26181.1 - 0.3 10.7 1.7 6.7 6.3 0.1 2.4 2 0 0 2 2 2 0 Dephospho-CoA kinase Pox_A32 PF04665.12 EWM26181.1 - 0.34 10.3 0.6 2.8 7.3 0.0 2.1 2 0 0 2 2 2 0 Poxvirus A32 protein DUF4229 PF14012.6 EWM26181.1 - 0.46 10.6 0.0 0.46 10.6 0.0 3.8 4 0 0 4 4 2 0 Protein of unknown function (DUF4229) Abhydrolase_6 PF12697.7 EWM26182.1 - 2.1e-19 71.0 1.2 2.1e-19 71.0 1.2 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EWM26182.1 - 3.4e-17 62.9 0.0 8.5e-17 61.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EWM26182.1 - 4.9e-12 45.6 0.0 1.1e-11 44.5 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EWM26182.1 - 0.0049 16.7 0.0 5.8 6.6 0.1 3.0 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Abhydro_lipase PF04083.16 EWM26182.1 - 0.096 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region PK PF00224.21 EWM26183.1 - 5.4e-108 361.0 0.3 6.8e-108 360.6 0.3 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EWM26183.1 - 2.2e-29 102.1 0.1 9.6e-29 100.0 0.1 2.2 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain Peptidase_M1_N PF17900.1 EWM26184.1 - 0.028 14.6 0.0 0.038 14.2 0.0 1.1 1 0 0 1 1 1 0 Peptidase M1 N-terminal domain VacA2 PF03077.14 EWM26184.1 - 0.17 11.8 0.0 0.4 10.6 0.0 1.6 1 0 0 1 1 1 0 Putative vacuolating cytotoxin Thioredoxin PF00085.20 EWM26185.1 - 1.8e-08 34.3 0.0 5e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 EWM26185.1 - 0.075 12.0 5.7 0.36 9.7 5.7 1.9 1 1 0 1 1 1 0 Phosducin Dynactin_p62 PF05502.13 EWM26185.1 - 0.25 10.1 2.3 0.3 9.8 2.3 1.2 1 0 0 1 1 1 0 Dynactin p62 family LCIB_C_CA PF18599.1 EWM26185.1 - 0.5 9.6 2.4 0.43 9.8 0.8 1.6 2 0 0 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Cwf_Cwc_15 PF04889.12 EWM26185.1 - 3.2 7.4 15.6 4.7 6.9 15.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DIE2_ALG10 PF04922.12 EWM26186.1 - 1.5e-101 340.5 0.0 2.1e-101 340.1 0.0 1.2 1 0 0 1 1 1 1 DIE2/ALG10 family Rieske PF00355.26 EWM26188.1 - 3.7e-21 74.9 0.0 7e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 EWM26188.1 - 3.3e-17 62.4 0.0 1.1e-16 60.8 0.0 2.0 1 0 0 1 1 1 1 Pheophorbide a oxygenase Rieske_2 PF13806.6 EWM26188.1 - 0.026 14.5 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Rieske-like [2Fe-2S] domain RPEL PF02755.15 EWM26189.1 - 0.00065 19.3 0.3 0.1 12.4 0.0 3.1 3 0 0 3 3 3 2 RPEL repeat SNF2_N PF00176.23 EWM26190.1 - 6.1e-53 179.8 0.0 8.9e-53 179.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EWM26190.1 - 0.00069 19.9 0.0 0.0013 19.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CtsR PF05848.11 EWM26190.1 - 0.077 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 CtsR N-terminal HTH domain Prok-RING_4 PF14447.6 EWM26190.1 - 0.23 11.3 12.8 0.5 10.3 12.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EWM26190.1 - 2.2 8.2 13.7 4.7 7.2 13.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EWM26190.1 - 4.9 7.1 13.8 12 5.9 13.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EWM26190.1 - 7.6 6.6 15.0 17 5.5 15.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain LRR_9 PF14580.6 EWM26191.1 - 9.8e-67 223.8 1.5 1.4e-66 223.3 1.5 1.2 1 0 0 1 1 1 1 Leucine-rich repeat SAP PF02037.27 EWM26191.1 - 4.2e-13 48.7 0.3 4.2e-13 48.7 0.3 1.8 2 0 0 2 2 2 1 SAP domain LRR_4 PF12799.7 EWM26191.1 - 1.9e-08 34.5 5.6 0.00049 20.4 0.5 3.4 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EWM26191.1 - 7.6e-07 28.8 5.2 4.3e-06 26.4 2.5 3.1 4 0 0 4 4 4 1 Leucine rich repeat Uso1_p115_C PF04871.13 EWM26191.1 - 0.02 15.3 1.4 0.02 15.3 1.4 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region SR-25 PF10500.9 EWM26191.1 - 0.36 10.4 7.3 0.2 11.2 1.2 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DEAD PF00270.29 EWM26192.1 - 5.5e-45 153.3 0.0 9e-45 152.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EWM26192.1 - 6.4e-24 84.4 0.0 1.3e-23 83.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SPRY PF00622.28 EWM26192.1 - 1.2e-17 64.1 0.1 2.2e-17 63.3 0.1 1.5 1 0 0 1 1 1 1 SPRY domain YbjM PF11045.8 EWM26193.1 - 0.057 13.6 0.7 0.17 12.0 0.7 1.8 1 0 0 1 1 1 0 Putative inner membrane protein of Enterobacteriaceae GLE1 PF07817.13 EWM26194.1 - 0.014 14.6 0.4 0.04 13.1 0.4 1.8 1 0 0 1 1 1 0 GLE1-like protein CDO_I PF05995.12 EWM26194.1 - 0.023 14.0 0.1 0.055 12.8 0.1 1.6 1 0 0 1 1 1 0 Cysteine dioxygenase type I DUF2730 PF10805.8 EWM26194.1 - 2.4 8.3 14.0 3.9 7.6 0.3 5.1 3 2 2 5 5 5 0 Protein of unknown function (DUF2730) YjcZ PF13990.6 EWM26194.1 - 3.4 7.0 13.7 4.3 6.6 2.4 3.2 2 1 1 3 3 3 0 YjcZ-like protein XAP5 PF04921.14 EWM26195.1 - 4.3e-77 259.3 0.2 4.3e-77 259.3 0.2 2.0 2 0 0 2 2 2 1 XAP5, circadian clock regulator CholecysA-Rec_N PF09193.10 EWM26196.1 - 0.056 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Cholecystokinin A receptor, N-terminal WD40 PF00400.32 EWM26197.1 - 2.9e-66 217.8 8.8 8.3e-07 29.6 0.2 11.3 11 0 0 11 11 11 9 WD domain, G-beta repeat Utp13 PF08625.11 EWM26197.1 - 8.2e-37 126.3 0.1 1.2e-36 125.7 0.1 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 EWM26197.1 - 1.5e-09 38.0 0.3 0.47 10.8 0.0 6.0 5 1 1 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EWM26197.1 - 0.00036 19.6 0.4 27 3.6 0.0 5.6 6 1 1 7 7 7 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EWM26197.1 - 0.0022 16.7 2.5 15 4.1 0.0 5.3 4 2 0 5 5 5 1 Nucleoporin Nup120/160 WD40_like PF17005.5 EWM26197.1 - 0.037 13.4 0.0 1.1 8.6 0.0 2.8 3 1 0 3 3 3 0 WD40-like domain TPR_14 PF13428.6 EWM26197.1 - 1.5 9.9 6.7 1.5 9.8 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat HEAT PF02985.22 EWM26198.1 - 0.018 15.2 0.0 0.052 13.8 0.0 1.9 1 0 0 1 1 1 0 HEAT repeat FGGY_N PF00370.21 EWM26199.1 - 2.4e-51 174.7 0.0 3e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain EMP24_GP25L PF01105.24 EWM26200.1 - 9.5e-21 74.6 0.0 1.2e-20 74.2 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PAS_10 PF13596.6 EWM26200.1 - 0.029 14.9 0.2 0.056 14.0 0.2 1.4 1 0 0 1 1 1 0 PAS domain Glyco_transf_34 PF05637.12 EWM26201.1 - 3.3e-10 40.1 0.0 1.2e-05 25.2 0.0 2.4 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family Gly_transf_sug PF04488.15 EWM26201.1 - 8.3e-08 32.8 0.0 5.5e-06 26.9 0.0 2.5 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Sigma70_r3 PF04539.16 EWM26203.1 - 2.9e-07 30.5 0.1 0.0019 18.2 0.0 2.8 2 0 0 2 2 2 2 Sigma-70 region 3 Sigma70_r2 PF04542.14 EWM26203.1 - 1.2e-05 25.0 0.0 3.3e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 EWM26203.1 - 2.4e-05 23.8 0.7 0.0092 15.5 0.0 2.8 2 0 0 2 2 2 2 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 EWM26203.1 - 0.00027 20.5 0.3 0.2 11.3 0.0 2.6 2 0 0 2 2 2 2 Sigma-70, region 4 Ribosomal_L14 PF00238.19 EWM26204.1 - 1.9e-10 40.9 0.0 3.2e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e DUF1604 PF07713.13 EWM26205.1 - 1.3e-32 111.5 3.3 1.3e-32 111.5 3.3 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.23 EWM26205.1 - 0.00057 19.7 3.2 0.0019 18.0 3.2 1.9 1 0 0 1 1 1 1 G-patch domain Mito_carr PF00153.27 EWM26206.1 - 4.5e-68 225.3 1.1 6.4e-23 80.5 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_6 PF13405.6 EWM26206.1 - 3.7e-15 54.5 3.0 0.003 17.3 0.0 4.8 5 0 0 5 5 5 3 EF-hand domain EF-hand_7 PF13499.6 EWM26206.1 - 2.2e-14 53.7 6.4 3.6e-07 30.5 1.3 4.9 4 1 1 5 5 5 4 EF-hand domain pair cNMP_binding PF00027.29 EWM26206.1 - 1.2e-13 50.9 0.0 3.3e-13 49.5 0.0 1.8 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain EF-hand_1 PF00036.32 EWM26206.1 - 5.6e-13 47.4 2.2 0.0011 18.3 0.0 5.2 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 EWM26206.1 - 3.5e-10 39.6 2.5 3.2e-05 23.7 0.0 4.3 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 EWM26206.1 - 7.6e-08 31.5 1.2 0.0017 17.8 0.1 3.8 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 EWM26206.1 - 0.0066 16.8 3.4 3.6 8.0 0.0 4.1 4 0 0 4 4 4 1 EF-hand domain DUF150_C PF17384.2 EWM26207.1 - 0.044 13.9 0.0 0.089 12.9 0.0 1.5 1 0 0 1 1 1 0 RimP C-terminal SH3 domain TB2_DP1_HVA22 PF03134.19 EWM26208.1 - 8.6e-16 57.6 2.3 1.3e-15 57.0 2.3 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Pkinase PF00069.25 EWM26209.1 - 1.4e-16 60.7 0.0 1.8e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 EWM26209.1 - 0.00021 20.7 0.0 0.00034 20.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 EWM26209.1 - 0.00072 18.9 0.0 0.0016 17.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase TP6A_N PF04406.14 EWM26210.1 - 1.2e-11 44.4 0.0 2e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase HIRAN PF08797.11 EWM26210.1 - 0.011 15.7 0.0 0.033 14.1 0.0 1.9 1 0 0 1 1 1 0 HIRAN domain DnaJ PF00226.31 EWM26211.1 - 1.8e-13 50.4 0.1 4.8e-13 49.0 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain RAP1 PF07218.11 EWM26211.1 - 0.086 11.1 1.9 0.1 10.9 1.9 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF883 PF05957.13 EWM26211.1 - 0.73 10.5 8.3 0.3 11.7 4.5 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Josephin PF02099.17 EWM26212.1 - 4.1e-13 49.7 0.0 8.7e-12 45.4 0.0 2.0 1 1 0 1 1 1 1 Josephin UcrQ PF02939.16 EWM26213.1 - 0.0014 18.5 0.2 0.0032 17.4 0.2 1.5 1 0 0 1 1 1 1 UcrQ family PAN_2 PF08276.11 EWM26213.1 - 0.14 12.3 0.4 0.25 11.5 0.4 1.4 1 0 0 1 1 1 0 PAN-like domain TPR_19 PF14559.6 EWM26214.1 - 4.2e-13 49.6 8.1 0.0013 19.2 0.3 7.0 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 EWM26214.1 - 3.3e-09 36.2 28.2 0.072 13.2 0.3 7.8 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 EWM26214.1 - 1.5e-08 35.1 14.2 0.11 13.1 0.3 5.9 6 0 0 6 6 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EWM26214.1 - 2.6e-08 33.9 21.9 0.00071 19.8 4.2 6.0 4 2 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EWM26214.1 - 8.1e-06 25.9 15.9 0.00033 20.8 0.8 5.7 5 2 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EWM26214.1 - 1.2e-05 24.9 15.6 0.15 11.9 0.9 6.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 EWM26214.1 - 0.0045 16.9 9.9 0.15 12.1 0.2 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EWM26214.1 - 0.006 16.6 7.0 0.28 11.3 0.1 4.0 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 EWM26214.1 - 0.0076 16.8 17.1 0.53 11.0 0.2 7.0 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 EWM26214.1 - 0.059 14.2 18.1 2 9.5 0.2 7.2 7 2 1 8 8 8 0 Tetratricopeptide repeat Coatomer_E PF04733.14 EWM26214.1 - 0.1 12.0 1.3 33 3.8 0.0 4.0 4 1 1 5 5 5 0 Coatomer epsilon subunit TPR_8 PF13181.6 EWM26214.1 - 0.29 11.5 5.8 15 6.1 0.3 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 EWM26214.1 - 0.59 10.9 8.1 4.8 8.1 0.0 4.9 6 0 0 6 6 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 EWM26214.1 - 6 7.0 12.5 14 5.8 0.3 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF974 PF06159.13 EWM26215.1 - 1.4e-33 116.7 0.0 2.6e-33 115.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Trs65 PF12735.7 EWM26215.1 - 0.00075 19.0 0.1 0.64 9.4 0.0 3.4 3 1 1 4 4 4 2 TRAPP trafficking subunit Trs65 Cu-oxidase_3 PF07732.15 EWM26216.1 - 0.029 14.4 0.0 0.088 12.8 0.0 1.8 2 0 0 2 2 2 0 Multicopper oxidase WD40 PF00400.32 EWM26217.1 - 1.1e-51 171.7 11.4 6.4e-09 36.3 0.1 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM26217.1 - 1.7e-21 76.3 0.4 0.00041 20.6 0.0 6.1 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EWM26217.1 - 1e-05 24.4 0.3 0.012 14.3 0.0 4.1 3 1 1 4 4 4 1 Nucleoporin Nup120/160 US22 PF02393.16 EWM26217.1 - 0.00071 19.8 0.1 0.0023 18.2 0.1 1.9 1 0 0 1 1 1 1 US22 like Ge1_WD40 PF16529.5 EWM26217.1 - 0.001 18.1 0.4 2.8 6.8 0.0 4.5 1 1 4 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 EWM26217.1 - 0.0037 16.4 0.0 0.16 11.0 0.0 2.7 2 1 0 3 3 3 1 Coatomer WD associated region PALB2_WD40 PF16756.5 EWM26217.1 - 0.018 14.0 1.4 3.7 6.4 0.2 3.5 1 1 2 3 3 3 0 Partner and localizer of BRCA2 WD40 domain WD40_like PF17005.5 EWM26217.1 - 0.027 13.8 0.0 1.3 8.2 0.0 2.9 3 1 1 4 4 4 0 WD40-like domain Hira PF07569.11 EWM26217.1 - 0.071 12.8 0.9 20 4.8 0.0 4.1 4 1 0 4 4 4 0 TUP1-like enhancer of split Toxin_28 PF08115.11 EWM26217.1 - 0.78 9.7 0.0 0.78 9.7 0.0 2.7 3 0 0 3 3 3 0 SFI toxin family PfkB PF00294.24 EWM26219.1 - 2.6e-38 132.0 0.0 8.9e-31 107.3 0.0 2.1 1 1 1 2 2 2 2 pfkB family carbohydrate kinase Gram_pos_anchor PF00746.21 EWM26219.1 - 0.044 13.7 0.6 0.087 12.8 0.6 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Nrap PF03813.14 EWM26219.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Nrap protein domain 1 Pro_isomerase PF00160.21 EWM26220.1 - 8.2e-19 68.4 0.0 1.2e-18 67.9 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Tmemb_14 PF03647.13 EWM26221.1 - 6.8e-17 62.0 9.9 8.8e-17 61.6 9.9 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C RnfC_N PF13375.6 EWM26221.1 - 0.064 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain MORN PF02493.20 EWM26222.1 - 2.1e-72 234.9 141.9 7.2e-06 25.6 2.1 24.4 25 0 0 25 25 25 20 MORN repeat Avl9 PF09794.9 EWM26222.1 - 6.7e-21 74.4 0.1 2.4e-15 56.1 0.0 3.2 2 1 0 2 2 2 2 Transport protein Avl9 DENN PF02141.21 EWM26222.1 - 4.1e-05 23.6 0.2 8.5e-05 22.6 0.2 1.5 1 1 0 1 1 1 1 DENN (AEX-3) domain SPA PF08616.10 EWM26222.1 - 0.00063 19.7 0.0 0.62 10.0 0.0 2.3 2 0 0 2 2 2 2 Stabilization of polarity axis ICL PF00463.21 EWM26223.1 - 2.9e-230 765.2 0.0 3.4e-230 765.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 EWM26223.1 - 2.3e-11 43.6 0.2 7.9e-11 41.9 0.0 1.9 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Glyco_hydro_3_C PF01915.22 EWM26224.1 - 9.3e-47 159.6 0.1 3.6e-44 151.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EWM26224.1 - 1e-38 133.5 0.0 2.6e-38 132.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EWM26224.1 - 0.001 19.2 0.0 0.002 18.2 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain SMC_N PF02463.19 EWM26225.1 - 2.2e-66 223.4 1.0 7.3e-66 221.7 1.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EWM26225.1 - 3.9e-21 75.5 0.1 1.6e-20 73.6 0.1 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 EWM26225.1 - 1.1e-09 39.1 16.2 1.1e-09 39.1 16.2 6.7 2 2 0 3 3 2 1 AAA domain AAA_21 PF13304.6 EWM26225.1 - 1.2e-08 35.1 3.3 0.00052 19.9 0.3 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system GAS PF13851.6 EWM26225.1 - 9.7e-05 21.8 4.9 9.7e-05 21.8 4.9 7.3 4 2 3 7 7 5 3 Growth-arrest specific micro-tubule binding AAA_29 PF13555.6 EWM26225.1 - 0.00086 19.0 0.7 0.0022 17.7 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain Spc7 PF08317.11 EWM26225.1 - 0.0016 17.4 26.2 0.0016 17.4 26.2 6.2 2 2 3 6 6 6 2 Spc7 kinetochore protein ABC_tran PF00005.27 EWM26225.1 - 0.064 13.8 0.1 0.064 13.8 0.1 5.3 4 2 0 5 5 5 0 ABC transporter CarD_CdnL_TRCF PF02559.16 EWM26225.1 - 0.62 10.8 5.2 2.8 8.7 1.6 3.9 1 1 1 2 2 2 0 CarD-like/TRCF domain HALZ PF02183.18 EWM26225.1 - 0.97 9.7 11.2 29 5.0 0.1 5.5 4 0 0 4 4 4 0 Homeobox associated leucine zipper APG6_N PF17675.1 EWM26225.1 - 6.1 7.4 122.5 0.24 11.9 13.6 8.4 2 2 4 7 7 7 0 Apg6 coiled-coil region Got1 PF04178.12 EWM26226.1 - 4.3e-31 107.6 16.6 1.9e-30 105.6 16.2 2.0 1 1 1 2 2 2 2 Got1/Sft2-like family Acyl_transf_3 PF01757.22 EWM26226.1 - 0.0054 15.8 9.5 0.11 11.5 7.7 2.0 1 1 0 1 1 1 1 Acyltransferase family MMPL PF03176.15 EWM26226.1 - 0.094 11.6 1.0 0.14 11.1 1.0 1.2 1 0 0 1 1 1 0 MMPL family Ac81 PF05820.11 EWM26226.1 - 0.12 12.0 3.5 0.24 11.0 3.5 1.5 1 0 0 1 1 1 0 Baculoviridae AC81 Wzy_C PF04932.15 EWM26226.1 - 0.44 10.2 3.5 0.11 12.1 0.3 1.7 2 0 0 2 2 2 0 O-Antigen ligase DUF4271 PF14093.6 EWM26226.1 - 3.1 7.7 15.1 8.6 6.2 15.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4271) PRA1 PF03208.19 EWM26226.1 - 5.1 6.7 10.1 8.8 5.9 10.1 1.4 1 1 0 1 1 1 0 PRA1 family protein DUF2614 PF11023.8 EWM26226.1 - 6.2 7.0 9.5 0.46 10.6 2.0 2.6 2 1 0 3 3 3 0 Zinc-ribbon containing domain Kinesin PF00225.23 EWM26228.1 - 2.2e-96 322.7 0.0 1e-95 320.5 0.0 2.2 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EWM26228.1 - 2.9e-22 79.2 0.0 1.8e-21 76.6 0.0 2.5 2 0 0 2 2 2 1 Microtubule binding VGPC1_C PF16799.5 EWM26228.1 - 0.3 11.1 8.7 17 5.5 0.0 5.2 4 0 0 4 4 4 0 C-terminal membrane-localisation domain of ion-channel, VCN1 zf-C4pol PF14260.6 EWM26228.1 - 6.3 7.4 9.1 25 5.4 1.3 5.1 3 0 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta ubiquitin PF00240.23 EWM26229.1 - 1.5e-34 117.6 0.6 2.2e-34 117.0 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S30 PF04758.14 EWM26229.1 - 3.9e-26 91.0 7.6 7.1e-26 90.2 7.6 1.4 1 0 0 1 1 1 1 Ribosomal protein S30 Rad60-SLD PF11976.8 EWM26229.1 - 1.6e-16 59.9 0.7 2.5e-16 59.2 0.7 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EWM26229.1 - 6.5e-06 26.5 0.1 2.2e-05 24.8 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 EWM26229.1 - 0.0017 18.9 0.3 0.0023 18.4 0.3 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EWM26229.1 - 0.003 17.6 0.2 0.013 15.5 0.2 2.1 1 1 1 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 EWM26229.1 - 0.0032 17.4 0.0 0.0047 16.8 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Sde2_N_Ubi PF13019.6 EWM26229.1 - 0.0047 16.8 0.1 0.006 16.4 0.1 1.2 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_5 PF18037.1 EWM26229.1 - 0.0078 16.5 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 EWM26229.1 - 0.045 13.8 0.8 11 6.1 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain MutS_V PF00488.21 EWM26231.1 - 2.6e-30 105.9 0.0 5.1e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 MutS domain V Smr PF01713.21 EWM26231.1 - 2.8e-10 40.4 0.2 8.8e-10 38.8 0.2 2.0 1 0 0 1 1 1 1 Smr domain AAA_21 PF13304.6 EWM26231.1 - 0.00027 20.8 0.2 0.018 14.8 0.1 2.7 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system Mod_r PF07200.13 EWM26231.1 - 0.054 13.6 8.7 0.28 11.3 9.4 1.8 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF4407 PF14362.6 EWM26231.1 - 0.081 12.3 5.8 0.17 11.2 5.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 EWM26231.1 - 0.1 11.4 9.3 0.24 10.2 9.3 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein ABC_tran_CTD PF16326.5 EWM26231.1 - 1.9 8.8 23.3 0.38 11.0 4.9 2.9 3 0 0 3 3 3 0 ABC transporter C-terminal domain KTI12 PF08433.10 EWM26232.1 - 2.6e-15 56.6 0.0 6.9e-15 55.2 0.0 1.6 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 EWM26232.1 - 5.1e-09 36.4 0.5 6.9e-08 32.8 0.0 2.6 3 1 0 3 3 3 1 AAA domain 6PF2K PF01591.18 EWM26232.1 - 0.095 12.0 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Vps51 PF08700.11 EWM26233.1 - 0.0086 16.1 5.5 0.019 15.0 5.5 1.5 1 0 0 1 1 1 1 Vps51/Vps67 Leu_zip PF15294.6 EWM26233.1 - 0.093 12.2 14.5 0.16 11.5 14.5 1.3 1 0 0 1 1 1 0 Leucine zipper DUF1993 PF09351.10 EWM26233.1 - 0.16 12.1 2.5 0.41 10.8 2.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1993) PRP1_N PF06424.12 EWM26233.1 - 0.17 12.3 9.1 0.37 11.2 9.1 1.5 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal KCT2 PF17818.1 EWM26233.1 - 0.61 10.2 3.2 1.1 9.3 3.2 1.4 1 0 0 1 1 1 0 Keratinocyte-associated gene product DUF1664 PF07889.12 EWM26233.1 - 0.77 9.8 5.6 1.5 8.9 5.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 EWM26233.1 - 1.9 7.8 12.3 3.8 6.8 12.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Csm1_N PF18504.1 EWM26233.1 - 3.2 8.1 19.1 26 5.3 2.3 3.4 1 1 1 2 2 2 0 Csm1 N-terminal domain Spc7 PF08317.11 EWM26233.1 - 3.4 6.4 16.1 5.6 5.7 16.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_23 PF13476.6 EWM26233.1 - 5.1 7.6 12.8 8.6 6.8 12.8 1.3 1 0 0 1 1 1 0 AAA domain DUF2730 PF10805.8 EWM26233.1 - 5.6 7.1 8.3 2.4 8.3 4.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Pex26 PF07163.12 EWM26233.1 - 6.1 6.1 6.7 0.67 9.2 0.1 2.1 2 0 0 2 2 2 0 Pex26 protein DUF4094 PF13334.6 EWM26233.1 - 7.7 7.0 15.1 59 4.2 3.0 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) TSC22 PF01166.18 EWM26233.1 - 9.9 6.6 11.9 12 6.2 1.6 3.1 2 1 1 3 3 3 0 TSC-22/dip/bun family Arm PF00514.23 EWM26234.1 - 5.5e-94 305.7 15.5 2.4e-13 49.6 0.0 9.6 10 0 0 10 10 10 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EWM26234.1 - 5.1e-28 97.1 0.1 1.9e-10 41.0 0.0 5.7 5 0 0 5 5 5 4 HEAT-like repeat HEAT_2 PF13646.6 EWM26234.1 - 1.8e-21 76.3 0.5 9e-09 35.6 0.0 5.8 1 1 5 6 6 6 5 HEAT repeats IBB PF01749.20 EWM26234.1 - 5.5e-21 74.8 0.8 2.3e-20 72.8 0.8 2.0 2 0 0 2 2 2 1 Importin beta binding domain Arm_3 PF16186.5 EWM26234.1 - 4.1e-16 58.3 0.4 2.8e-15 55.6 0.0 2.6 3 0 0 3 3 3 1 Atypical Arm repeat HEAT PF02985.22 EWM26234.1 - 1.3e-15 56.2 2.5 9.6e-06 25.4 0.0 7.7 8 1 0 8 8 8 1 HEAT repeat V-ATPase_H_C PF11698.8 EWM26234.1 - 1.3e-08 35.0 0.0 0.37 10.9 0.0 4.6 4 2 0 4 4 4 3 V-ATPase subunit H Arm_2 PF04826.13 EWM26234.1 - 4.2e-08 32.9 0.0 0.046 13.2 0.0 3.5 1 1 2 4 4 4 2 Armadillo-like Adaptin_N PF01602.20 EWM26234.1 - 1.7e-06 26.9 0.0 0.45 9.0 0.0 3.6 1 1 2 3 3 3 3 Adaptin N terminal region HEAT_PBS PF03130.16 EWM26234.1 - 1.4e-05 25.3 0.8 0.35 11.7 0.1 5.3 5 0 0 5 5 4 1 PBS lyase HEAT-like repeat CTNNBL PF08216.11 EWM26234.1 - 0.00077 19.6 0.4 7.4 6.8 0.0 4.7 6 0 0 6 6 5 1 Catenin-beta-like, Arm-motif containing nuclear Atx10homo_assoc PF09759.9 EWM26234.1 - 0.0029 17.6 0.1 1.2 9.2 0.0 3.5 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain DUF3361 PF11841.8 EWM26234.1 - 0.0071 16.3 0.1 11 5.9 0.1 3.8 3 1 0 4 4 4 0 Domain of unknown function (DUF3361) RICTOR_V PF14668.6 EWM26234.1 - 0.02 15.1 1.5 1.1 9.5 0.0 4.0 4 1 2 6 6 6 0 Rapamycin-insensitive companion of mTOR, domain 5 NopRA1 PF16201.5 EWM26234.1 - 0.049 13.2 0.0 19 4.8 0.0 3.8 2 1 1 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 Mo25 PF08569.11 EWM26234.1 - 0.21 10.9 0.0 2.2 7.6 0.0 2.1 1 1 1 2 2 2 0 Mo25-like WW PF00397.26 EWM26235.1 - 2.8e-10 40.1 7.6 1.2e-09 38.1 7.6 2.2 1 0 0 1 1 1 1 WW domain WW PF00397.26 EWM26236.1 - 2.8e-10 40.1 7.6 1.2e-09 38.1 7.6 2.2 1 0 0 1 1 1 1 WW domain AMP-binding PF00501.28 EWM26237.1 - 3.4e-11 42.4 0.0 6.2e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme AAA_12 PF13087.6 EWM26238.1 - 4.6e-46 157.0 0.0 7.4e-46 156.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain Dna2 PF08696.11 EWM26238.1 - 4e-37 128.0 0.0 6.3e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_11 PF13086.6 EWM26238.1 - 9.3e-31 107.6 0.3 3.3e-20 73.0 0.1 2.3 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 EWM26238.1 - 2.3e-13 50.3 0.3 4.9e-13 49.2 0.3 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EWM26238.1 - 1.1e-09 38.8 1.1 5.2e-09 36.6 0.2 2.4 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 EWM26238.1 - 0.002 17.9 0.0 0.0071 16.2 0.0 2.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EWM26238.1 - 0.0025 17.6 0.1 2.4 7.8 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 EWM26238.1 - 0.012 15.6 0.0 0.04 13.9 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 EWM26238.1 - 0.016 15.1 0.0 0.048 13.5 0.0 1.8 1 1 0 1 1 1 0 Helicase UvrD-helicase PF00580.21 EWM26238.1 - 0.024 14.2 0.2 0.062 12.8 0.1 1.7 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 EWM26238.1 - 0.033 14.5 0.1 0.29 11.4 0.1 2.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EWM26238.1 - 0.05 13.2 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF4911 PF16256.5 EWM26238.1 - 0.057 13.4 0.0 0.27 11.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4911) PhoH PF02562.16 EWM26238.1 - 0.13 11.7 0.0 0.32 10.4 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EWM26238.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF1997 PF09366.10 EWM26239.1 - 7.8e-21 74.8 0.0 1e-20 74.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1997) Bac_DNA_binding PF00216.21 EWM26240.1 - 3.8e-27 94.3 0.2 4.9e-27 94.0 0.2 1.1 1 0 0 1 1 1 1 Bacterial DNA-binding protein HU-HIG PF18291.1 EWM26240.1 - 6.2e-10 39.2 0.0 7.4e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 HU domain fused to wHTH, Ig, or Glycine-rich motif HU-CCDC81_euk_1 PF14908.6 EWM26240.1 - 0.00092 19.3 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 HU-DNA_bdg PF14848.6 EWM26240.1 - 0.0035 17.3 0.0 0.0054 16.7 0.0 1.3 1 0 0 1 1 1 1 DNA-binding domain Wzy_C_2 PF11846.8 EWM26241.1 - 1.7 8.5 4.7 5 7.0 4.7 1.8 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal CpeT PF06206.11 EWM26242.1 - 1.4e-14 54.5 0.0 6.8e-09 35.9 0.0 2.1 2 0 0 2 2 2 2 CpeT/CpcT family (DUF1001) HSP33 PF01430.19 EWM26243.1 - 1.2e-59 201.9 0.0 1.4e-59 201.7 0.0 1.0 1 0 0 1 1 1 1 Hsp33 protein SnoaL_2 PF12680.7 EWM26244.1 - 0.11 13.1 0.0 0.15 12.7 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like domain Proteasome PF00227.26 EWM26245.1 - 1.6e-23 83.2 0.0 9.5e-13 48.1 0.0 2.3 2 0 0 2 2 2 2 Proteasome subunit CMS1 PF14617.6 EWM26246.1 - 5.2e-25 88.2 0.1 6.8e-25 87.8 0.1 1.1 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 EWM26246.1 - 2.4e-05 24.2 0.1 3.3e-05 23.7 0.1 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase RRM_1 PF00076.22 EWM26247.1 - 9.8e-16 57.3 0.1 3.1e-15 55.7 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EWM26247.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif Peptidase_M24 PF00557.24 EWM26248.1 - 6.5e-55 186.1 0.0 9.2e-55 185.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EWM26248.1 - 2.4e-24 85.4 0.0 4.2e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF5074 PF16819.5 EWM26248.1 - 0.094 12.8 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5074) RuvX PF03652.15 EWM26249.1 - 1.5e-22 80.5 0.0 4.5e-15 56.2 0.0 2.2 2 0 0 2 2 2 2 Holliday junction resolvase ATG11 PF10377.9 EWM26250.1 - 1.6e-13 50.8 0.0 7.8e-13 48.6 0.0 1.9 2 0 0 2 2 2 1 Autophagy-related protein 11 HSCB_C PF07743.13 EWM26251.1 - 3.2e-14 53.2 2.1 3.2e-14 53.2 2.1 2.7 3 0 0 3 3 3 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 EWM26251.1 - 2.3e-05 24.4 0.2 4.5e-05 23.5 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain TRH PF05438.12 EWM26252.1 - 0.053 13.2 1.8 0.069 12.9 1.8 1.1 1 0 0 1 1 1 0 Thyrotropin-releasing hormone (TRH) DNA_pol_B PF00136.21 EWM26253.1 - 5.3e-83 279.2 0.0 7.2e-83 278.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EWM26253.1 - 1e-20 74.2 0.0 1.6e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EWM26253.1 - 9.1e-07 29.3 14.0 1.8e-06 28.3 14.0 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 EWM26253.1 - 0.3 9.9 0.0 0.49 9.2 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral MNNL PF07657.13 EWM26253.1 - 1.5 8.9 5.9 3 7.9 5.9 1.5 1 0 0 1 1 1 0 N terminus of Notch ligand Abhydrolase_1 PF00561.20 EWM26254.1 - 4.5e-36 124.8 0.0 5.4e-35 121.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EWM26254.1 - 7.1e-06 26.8 1.3 1.4e-05 25.9 1.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 EWM26254.1 - 0.00025 21.1 0.0 0.0023 18.0 0.0 2.5 3 0 0 3 3 3 1 TAP-like protein RVT_3 PF13456.6 EWM26257.1 - 5.9e-27 93.9 0.2 9.4e-27 93.3 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase-like Cauli_VI PF01693.16 EWM26257.1 - 2.7e-12 46.8 0.2 4.9e-12 46.0 0.2 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin RNase_H PF00075.24 EWM26257.1 - 7.6e-08 32.7 0.1 2.3e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 RNase H Sulfatase PF00884.23 EWM26258.1 - 2.5e-65 220.9 0.2 3.2e-65 220.6 0.2 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 EWM26258.1 - 0.0019 18.9 0.0 0.0061 17.3 0.0 1.8 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.22 EWM26258.1 - 0.095 12.3 0.0 6.4 6.3 0.0 2.1 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase Mito_carr PF00153.27 EWM26259.1 - 7.3e-66 218.2 3.1 2e-23 82.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Got1 PF04178.12 EWM26260.1 - 2.7e-08 34.2 8.6 2.7e-08 34.2 8.6 1.8 2 0 0 2 2 2 1 Got1/Sft2-like family Aminotran_1_2 PF00155.21 EWM26261.1 - 7e-46 157.0 0.0 1.2e-45 156.3 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EWM26261.1 - 0.0001 21.7 0.0 0.00024 20.5 0.0 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family RNA_pol_L_2 PF13656.6 EWM26262.1 - 8.6e-27 92.7 0.0 1.3e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EWM26262.1 - 6.4e-07 28.7 0.0 1e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF842 PF05811.13 EWM26263.1 - 2.4e-34 117.8 7.7 2.7e-34 117.7 7.7 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) zf-Tim10_DDP PF02953.15 EWM26263.1 - 0.0015 18.1 6.3 0.5 10.1 0.1 3.4 1 1 2 3 3 3 3 Tim10/DDP family zinc finger DUF2408 PF10303.9 EWM26263.1 - 0.04 14.5 0.2 0.054 14.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Bin3 PF06859.12 EWM26264.1 - 1.3e-11 45.0 0.0 2.5e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_31 PF13847.6 EWM26264.1 - 2.6e-06 27.3 0.0 0.00045 20.1 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 EWM26264.1 - 0.00021 21.9 0.1 0.001 19.7 0.0 2.1 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 EWM26264.1 - 0.0057 17.4 0.0 0.026 15.3 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM26264.1 - 0.0084 16.7 0.0 0.041 14.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain DUF4110 PF13422.6 EWM26264.1 - 0.039 14.0 1.6 0.061 13.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) DUF1724 PF08350.10 EWM26264.1 - 0.12 12.6 0.1 0.33 11.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1724) SAGA-Tad1 PF12767.7 EWM26265.1 - 3.5e-13 49.8 0.0 2.9e-12 46.9 0.0 2.3 2 0 0 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit TruB_C PF09142.11 EWM26265.1 - 2.4 8.0 10.8 2.1 8.2 3.3 2.7 2 0 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal 2OG-FeII_Oxy_2 PF13532.6 EWM26266.1 - 3.4e-27 95.9 0.0 6.4e-25 88.5 0.0 3.0 2 1 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily ABC1 PF03109.16 EWM26267.1 - 9.5e-34 116.1 0.0 1.9e-33 115.1 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EWM26267.1 - 0.032 14.2 0.7 0.91 9.4 0.1 3.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Inhibitor_I78 PF11720.8 EWM26267.1 - 0.076 13.1 0.0 0.3 11.2 0.0 2.0 1 0 0 1 1 1 0 Peptidase inhibitor I78 family Amidase PF01425.21 EWM26268.1 - 1.4e-139 466.0 2.2 1.6e-139 465.8 2.2 1.0 1 0 0 1 1 1 1 Amidase PCNA_N PF00705.18 EWM26272.1 - 1.2e-55 186.7 0.6 1.9e-55 186.0 0.6 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 EWM26272.1 - 8e-49 165.1 0.0 5.8e-48 162.3 0.0 2.1 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 EWM26272.1 - 2e-05 24.2 0.0 2.5e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.12 EWM26272.1 - 0.0016 17.6 0.0 0.1 11.7 0.0 2.1 2 0 0 2 2 2 2 Hus1-like protein LSM PF01423.22 EWM26273.1 - 2.4e-18 65.6 0.1 4.6e-18 64.7 0.3 1.3 2 0 0 2 2 2 1 LSM domain Aconitase PF00330.20 EWM26274.1 - 1.4e-104 350.6 0.1 7.5e-103 345.0 0.1 2.7 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EWM26274.1 - 4.4e-18 65.9 0.0 7.9e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain PKD_channel PF08016.12 EWM26275.1 - 7.2e-10 38.1 3.2 1e-09 37.6 3.2 1.1 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 EWM26275.1 - 1.2e-05 24.7 6.5 1.5e-05 24.3 6.5 1.1 1 0 0 1 1 1 1 Ion transport protein PUF PF00806.19 EWM26276.1 - 0.0005 19.6 0.0 0.98 9.2 0.0 4.7 5 0 0 5 5 5 2 Pumilio-family RNA binding repeat CPL PF08144.11 EWM26276.1 - 0.032 14.6 0.0 0.19 12.1 0.0 2.5 1 1 0 1 1 1 0 CPL (NUC119) domain Kinesin PF00225.23 EWM26277.1 - 5.4e-103 344.4 0.0 8.2e-103 343.8 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EWM26277.1 - 2.9e-22 79.2 0.0 7.2e-22 77.9 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding Laminin_B PF00052.18 EWM26277.1 - 0.036 14.0 0.1 0.14 12.0 0.1 2.0 1 0 0 1 1 1 0 Laminin B (Domain IV) ATG16 PF08614.11 EWM26277.1 - 0.096 12.9 13.5 0.024 14.9 5.7 2.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 EWM26277.1 - 0.23 11.5 6.0 0.56 10.2 6.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) HIP1_clath_bdg PF16515.5 EWM26277.1 - 0.45 11.2 16.7 1.9 9.1 9.9 2.7 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Prominin PF05478.11 EWM26277.1 - 1.3 6.9 3.3 2.1 6.2 3.3 1.2 1 0 0 1 1 1 0 Prominin DUF641 PF04859.12 EWM26277.1 - 2.4 8.5 12.2 1.2 9.5 7.9 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Fib_alpha PF08702.10 EWM26277.1 - 3.9 7.7 6.9 1 9.5 2.9 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Ndc1_Nup PF09531.10 EWM26278.1 - 0.21 10.3 0.0 0.4 9.3 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Peptidase_S9 PF00326.21 EWM26279.1 - 2.1e-06 27.4 0.0 4.2e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EWM26279.1 - 5.6e-05 22.5 0.0 0.024 13.9 0.0 3.0 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EWM26279.1 - 6.7e-05 22.8 0.0 0.00019 21.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Glyco_trans_4_4 PF13579.6 EWM26279.1 - 0.37 11.2 4.8 0.33 11.4 3.1 1.9 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain zf-CCHC_3 PF13917.6 EWM26280.1 - 1.2e-08 34.8 1.3 2e-08 34.1 0.5 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.23 EWM26280.1 - 0.0064 16.5 3.4 0.011 15.8 3.4 1.4 1 0 0 1 1 1 1 Zinc knuckle SR-25 PF10500.9 EWM26280.1 - 0.11 12.1 37.3 0.17 11.4 37.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Nefa_Nip30_N PF10187.9 EWM26281.1 - 1e-15 57.9 14.3 1e-15 57.9 14.3 2.2 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF572 PF04502.13 EWM26281.1 - 0.0031 17.2 20.4 0.0046 16.6 20.4 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) AFG1_ATPase PF03969.16 EWM26281.1 - 0.039 12.8 0.8 0.046 12.6 0.8 1.2 1 0 0 1 1 1 0 AFG1-like ATPase TPR_1 PF00515.28 EWM26282.1 - 3.3e-44 147.0 29.9 2.9e-06 26.9 1.1 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 EWM26282.1 - 2.8e-36 120.7 31.8 0.0001 22.1 0.4 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat STI1 PF17830.1 EWM26282.1 - 1.9e-29 101.4 0.1 2.2e-13 49.9 0.0 3.2 3 0 0 3 3 2 2 STI1 domain TPR_11 PF13414.6 EWM26282.1 - 3.4e-27 93.8 26.3 3.8e-09 36.1 0.4 8.3 6 2 2 8 8 8 6 TPR repeat TPR_8 PF13181.6 EWM26282.1 - 2.7e-24 83.3 28.7 0.0005 20.1 0.0 8.5 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_16 PF13432.6 EWM26282.1 - 4.4e-23 81.7 26.4 7.1e-08 33.0 1.2 6.3 4 2 1 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 EWM26282.1 - 1.2e-18 66.2 21.4 0.023 15.5 0.1 9.6 4 3 5 9 9 9 5 Tetratricopeptide repeat TPR_17 PF13431.6 EWM26282.1 - 1.4e-17 62.7 13.6 0.001 19.3 0.5 7.9 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 EWM26282.1 - 1.7e-17 63.4 20.9 1.4e-05 25.3 0.1 7.1 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 EWM26282.1 - 8.5e-12 45.4 20.9 0.0019 18.7 0.4 6.4 4 2 1 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 EWM26282.1 - 1e-10 41.6 3.8 0.22 11.7 0.4 5.9 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 EWM26282.1 - 1.2e-10 40.6 12.7 0.071 13.2 0.1 8.4 8 1 1 9 9 8 2 Tetratricopeptide repeat BTAD PF03704.17 EWM26282.1 - 2.4e-05 24.8 19.5 0.00054 20.4 3.4 4.8 4 1 0 4 4 4 1 Bacterial transcriptional activator domain TPR_10 PF13374.6 EWM26282.1 - 2.6e-05 23.9 25.5 0.78 9.7 0.3 8.5 9 0 0 9 9 9 2 Tetratricopeptide repeat NARP1 PF12569.8 EWM26282.1 - 8.7e-05 21.6 12.6 0.16 10.9 1.4 4.9 2 1 4 6 6 6 3 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.6 EWM26282.1 - 0.00044 20.3 5.9 0.95 9.6 0.0 5.0 6 0 0 6 6 5 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 EWM26282.1 - 0.00082 19.8 25.4 0.69 10.7 0.7 8.2 9 0 0 9 9 7 1 Tetratricopeptide repeat DUF3856 PF12968.7 EWM26282.1 - 0.0015 18.6 9.4 0.2 11.7 0.9 4.8 3 2 0 3 3 3 1 Domain of Unknown Function (DUF3856) MIT PF04212.18 EWM26282.1 - 0.0053 16.8 24.4 0.05 13.7 0.8 6.2 6 1 0 6 6 6 2 MIT (microtubule interacting and transport) domain TPR_MalT PF17874.1 EWM26282.1 - 0.0055 16.1 0.6 0.019 14.3 0.1 2.2 2 0 0 2 2 2 1 MalT-like TPR region RPN7 PF10602.9 EWM26282.1 - 0.58 9.8 12.4 3.7 7.2 0.1 4.4 2 1 2 4 4 4 0 26S proteasome subunit RPN7 TPR_21 PF09976.9 EWM26282.1 - 2.8 7.6 26.2 1.4 8.6 1.5 5.6 3 1 3 6 6 6 0 Tetratricopeptide repeat-like domain DUF737 PF05300.11 EWM26282.1 - 4.6 7.5 14.1 44 4.3 13.8 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF737) adh_short_C2 PF13561.6 EWM26283.1 - 2.5e-51 174.5 1.9 3.8e-51 173.9 1.9 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EWM26283.1 - 2.6e-49 167.4 1.5 3.1e-49 167.1 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EWM26283.1 - 2e-10 40.9 0.9 2.9e-10 40.3 0.9 1.2 1 0 0 1 1 1 1 KR domain Methyltransf_11 PF08241.12 EWM26283.1 - 0.0043 17.7 0.0 0.01 16.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain 3HCDH_N PF02737.18 EWM26283.1 - 0.0075 16.2 0.8 0.013 15.4 0.8 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_12 PF08242.12 EWM26283.1 - 0.08 13.7 0.0 0.15 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EWM26283.1 - 0.11 13.2 0.0 0.29 11.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain zf-UBR PF02207.20 EWM26284.1 - 1.5e-17 63.5 14.2 3.4e-17 62.4 14.2 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 EWM26284.1 - 1.1e-08 34.7 0.0 2.6e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-B_box PF00643.24 EWM26284.1 - 1.1 9.4 10.1 0.45 10.7 6.6 2.1 2 0 0 2 2 2 0 B-box zinc finger ORC6 PF05460.13 EWM26284.1 - 1.4 8.1 3.0 1.4 8.1 0.9 2.0 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Pkinase PF00069.25 EWM26285.1 - 2.3e-76 256.7 0.0 3.1e-76 256.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM26285.1 - 5.3e-38 130.8 0.0 7.9e-38 130.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EWM26285.1 - 8.3e-07 28.6 0.3 1.9e-06 27.4 0.3 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EWM26285.1 - 0.00044 19.7 0.0 0.00079 18.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EWM26285.1 - 0.013 15.4 0.0 0.045 13.7 0.0 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 EWM26285.1 - 0.053 13.1 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family adh_short PF00106.25 EWM26286.1 - 4.3e-27 94.8 0.0 5.7e-26 91.2 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EWM26286.1 - 2.2e-12 47.1 0.0 4.2e-12 46.1 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM26286.1 - 6.9e-07 29.3 0.0 1.3e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EWM26286.1 - 4.8e-05 22.9 0.0 9e-05 22.0 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family UTP25 PF06862.12 EWM26287.1 - 1.2e-134 449.7 0.0 1.5e-69 235.1 0.0 3.1 1 1 1 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 THF_DHG_CYH_C PF02882.19 EWM26288.1 - 8.6e-64 213.7 2.0 1.4e-63 213.0 1.5 1.6 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EWM26288.1 - 1.8e-41 141.0 0.0 2.9e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 EWM26288.1 - 0.025 13.5 0.2 0.044 12.7 0.2 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family GH114_assoc PF14741.6 EWM26288.1 - 0.14 12.4 0.1 0.63 10.3 0.0 1.9 2 0 0 2 2 2 0 N-terminal glycosyl-hydrolase-114-associated domain WD40 PF00400.32 EWM26289.1 - 5.2e-10 39.7 0.6 1 10.4 0.0 6.9 7 0 0 7 7 7 3 WD domain, G-beta repeat RSN1_7TM PF02714.15 EWM26290.1 - 2.1e-46 158.5 19.8 2.8e-46 158.1 19.8 1.2 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EWM26290.1 - 3.9e-06 27.2 0.0 6.1e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter IDO PF01231.18 EWM26292.1 - 3.5e-83 279.8 0.0 1e-30 106.9 0.0 3.1 3 0 0 3 3 3 3 Indoleamine 2,3-dioxygenase AAA_21 PF13304.6 EWM26293.1 - 0.0077 16.1 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 EWM26294.1 - 3.5e-10 40.5 0.0 6.3e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EWM26294.1 - 5.9e-06 25.6 7.3 7e-06 25.4 7.3 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein SRP54 PF00448.22 EWM26294.1 - 0.027 14.1 0.1 0.05 13.2 0.0 1.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 EWM26295.1 - 5.4e-30 104.7 0.1 9e-30 104.0 0.1 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EWM26295.1 - 2.6e-21 76.1 12.9 3.7e-21 75.6 12.9 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 EWM26295.1 - 2.5e-09 37.4 0.0 2.2e-05 24.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_2 PF12679.7 EWM26295.1 - 0.0037 16.6 13.9 0.0073 15.6 13.9 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein SMC_N PF02463.19 EWM26295.1 - 0.0069 15.9 0.0 4.1 6.8 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EWM26295.1 - 0.011 15.5 0.6 0.028 14.1 0.6 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EWM26295.1 - 0.012 15.6 0.1 0.022 14.7 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 EWM26295.1 - 0.14 12.7 1.6 0.17 12.4 0.4 1.6 2 0 0 2 2 2 0 AAA domain DUF2717 PF10911.8 EWM26295.1 - 0.14 11.9 0.0 3.5 7.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2717) SCAMP PF04144.13 EWM26295.1 - 2.1 8.7 21.6 0.045 14.1 13.7 2.2 2 1 0 2 2 2 0 SCAMP family ABC_tran PF00005.27 EWM26296.1 - 2.3e-13 50.8 0.0 3.9e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EWM26296.1 - 1.3e-06 27.8 8.6 1.6e-06 27.5 8.6 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein SRP54 PF00448.22 EWM26296.1 - 0.028 14.1 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain VWA_2 PF13519.6 EWM26297.1 - 1.1e-22 80.6 0.0 3e-22 79.3 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 EWM26297.1 - 2.2e-06 27.6 0.0 3.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 EWM26297.1 - 1.6e-05 24.5 18.9 0.015 15.2 2.8 3.5 3 0 0 3 3 3 2 Ubiquitin interaction motif VWA PF00092.28 EWM26297.1 - 0.00014 22.2 0.3 0.00024 21.4 0.1 1.5 2 0 0 2 2 2 1 von Willebrand factor type A domain PDH PF02153.17 EWM26297.1 - 0.0092 15.0 0.1 0.015 14.3 0.1 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase RAP80_UIM PF18282.1 EWM26297.1 - 2.9 7.7 11.9 0.49 10.2 0.3 3.0 3 0 0 3 3 3 0 RAP80 N-terminal ubiquitin interaction motif DNA_pol3_delta2 PF13177.6 EWM26298.1 - 3.2e-11 43.3 0.0 5e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 EWM26298.1 - 6e-08 33.2 0.0 1.5e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EWM26298.1 - 2.5e-05 24.7 0.3 0.00046 20.6 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EWM26298.1 - 0.00064 19.5 0.0 0.069 12.9 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Rep_fac_C PF08542.11 EWM26298.1 - 0.00079 19.8 0.0 0.002 18.5 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_11 PF13086.6 EWM26298.1 - 0.01 15.6 0.8 0.19 11.5 0.9 2.4 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EWM26298.1 - 0.013 15.8 0.0 0.057 13.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EWM26298.1 - 0.02 14.8 0.0 0.035 14.0 0.0 1.6 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_5 PF07728.14 EWM26298.1 - 0.02 14.9 0.2 0.12 12.4 0.2 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EWM26298.1 - 0.025 14.0 0.0 0.44 9.9 0.0 2.5 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 EWM26298.1 - 0.054 13.6 0.1 0.72 10.0 0.1 2.5 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 EWM26298.1 - 0.085 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain CNOT11 PF10155.9 EWM26299.1 - 1.2e-54 183.7 6.9 2.1e-54 183.0 6.9 1.4 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 Creb_binding PF09030.10 EWM26299.1 - 0.013 16.1 0.0 0.61 10.8 0.0 2.4 2 0 0 2 2 2 0 Creb binding COQ7 PF03232.13 EWM26300.1 - 1.7e-34 119.1 0.0 2.7e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Acyl_transf_1 PF00698.21 EWM26301.1 - 5.3e-52 177.3 1.2 9.1e-52 176.5 0.2 1.9 2 0 0 2 2 2 1 Acyl transferase domain KR PF08659.10 EWM26301.1 - 7.4e-44 149.8 1.4 1.1e-43 149.2 0.2 2.0 2 0 0 2 2 2 1 KR domain ketoacyl-synt PF00109.26 EWM26301.1 - 5.2e-41 140.9 0.0 1.3e-40 139.6 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EWM26301.1 - 2.4e-23 82.4 0.0 1.1e-22 80.2 0.0 2.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 EWM26301.1 - 3.3e-19 69.9 0.0 6.9e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain ADH_zinc_N_2 PF13602.6 EWM26301.1 - 8.1e-15 56.1 0.0 3.4e-14 54.0 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PS-DH PF14765.6 EWM26301.1 - 2.3e-12 46.8 0.0 5.7e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EWM26301.1 - 3e-12 47.0 0.7 1.7e-10 41.3 0.0 2.6 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 EWM26301.1 - 6.8e-12 45.5 0.7 3.3e-11 43.3 0.2 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 EWM26301.1 - 4.9e-10 39.2 1.1 2.5e-09 36.9 0.1 2.5 2 0 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.25 EWM26301.1 - 1.1e-07 32.1 0.0 2.9e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 EWM26301.1 - 3e-06 27.1 0.0 9.7e-06 25.4 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Abhydrolase_6 PF12697.7 EWM26301.1 - 2.1e-05 25.3 0.8 2.1e-05 25.3 0.8 3.4 3 0 0 3 3 3 1 Alpha/beta hydrolase family Thiolase_N PF00108.23 EWM26301.1 - 0.057 12.8 0.1 0.17 11.2 0.1 1.7 1 0 0 1 1 1 0 Thiolase, N-terminal domain ACP_syn_III PF08545.10 EWM26301.1 - 0.1 12.5 0.2 0.66 9.9 0.3 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Omptin PF01278.20 EWM26301.1 - 0.12 11.4 0.6 3.5 6.6 0.1 2.3 2 0 0 2 2 2 0 Omptin family Melibiase_2 PF16499.5 EWM26302.1 - 1.5e-77 260.6 0.0 2.2e-77 260.1 0.0 1.2 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 EWM26302.1 - 1.2e-15 57.3 0.0 3.1e-15 56.0 0.0 1.8 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 EWM26302.1 - 6.9e-05 22.0 0.0 0.00012 21.2 0.0 1.2 1 0 0 1 1 1 1 Melibiase Ricin_B_lectin PF00652.22 EWM26302.1 - 0.018 15.3 0.0 0.056 13.7 0.0 1.8 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain MRP-L46 PF11788.8 EWM26303.1 - 2.4e-05 25.0 0.2 0.00063 20.5 0.0 2.4 1 1 0 2 2 2 1 39S mitochondrial ribosomal protein L46 Pkinase PF00069.25 EWM26304.1 - 1.4e-75 254.1 0.0 1.7e-75 253.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM26304.1 - 8.7e-34 117.0 0.0 1.1e-33 116.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EWM26304.1 - 0.00034 20.0 0.1 0.068 12.5 0.0 2.3 1 1 1 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 EWM26304.1 - 0.0031 16.5 0.1 0.032 13.2 0.1 2.0 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EWM26304.1 - 0.015 15.3 0.1 0.025 14.5 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EWM26304.1 - 0.019 14.3 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_S9_N PF02897.15 EWM26305.1 - 1.8e-103 346.5 0.0 2.8e-103 345.9 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 EWM26305.1 - 4.7e-63 212.5 0.0 9e-63 211.6 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family SWIRM-assoc_2 PF16496.5 EWM26305.1 - 0.073 11.9 0.8 0.11 11.3 0.8 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal AP3D1 PF06375.11 EWM26305.1 - 0.69 10.1 4.0 1.2 9.3 4.0 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 NAD_binding_10 PF13460.6 EWM26306.1 - 7.2e-23 81.4 0.1 2e-22 80.0 0.1 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EWM26306.1 - 1.1e-08 34.9 0.0 1.8e-08 34.2 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EWM26306.1 - 3.5e-05 22.9 0.0 4.6e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 EWM26306.1 - 0.0023 18.0 0.0 0.0038 17.3 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NmrA PF05368.13 EWM26306.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family RibD_C PF01872.17 EWM26306.1 - 0.017 14.9 0.1 2.5 7.9 0.0 2.2 1 1 0 2 2 2 0 RibD C-terminal domain KR PF08659.10 EWM26306.1 - 0.024 14.6 0.0 0.22 11.4 0.0 2.1 2 0 0 2 2 2 0 KR domain adh_short PF00106.25 EWM26306.1 - 0.072 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Ank_2 PF12796.7 EWM26307.1 - 1.4e-05 25.6 0.3 3.3e-05 24.4 0.3 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EWM26307.1 - 0.00025 21.5 1.3 0.0034 17.9 0.0 3.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 EWM26307.1 - 0.0083 16.5 2.0 0.014 15.9 0.5 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 EWM26307.1 - 0.099 13.3 0.9 0.41 11.4 0.1 2.6 2 0 0 2 2 2 0 Ankyrin repeat DUF3670 PF12419.8 EWM26308.1 - 0.012 15.5 0.1 0.022 14.6 0.1 1.4 1 0 0 1 1 1 0 SNF2 Helicase protein DUF5122 PF17164.4 EWM26308.1 - 0.16 12.3 0.0 1.3 9.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5122) beta-propeller NnrS PF05940.12 EWM26308.1 - 0.63 9.4 4.9 0.066 12.6 0.6 1.4 2 0 0 2 2 2 0 NnrS protein Myb_DNA-binding PF00249.31 EWM26309.1 - 9.2e-40 134.6 13.6 4.7e-14 52.3 2.2 3.6 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EWM26309.1 - 1.1e-29 102.4 7.2 3.8e-14 52.7 0.1 3.5 1 1 2 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 EWM26309.1 - 0.00043 20.3 0.0 3.2 7.8 0.0 3.2 2 1 1 3 3 3 2 SLIDE Myb_DNA-bind_7 PF15963.5 EWM26309.1 - 0.0033 17.3 0.3 0.019 14.8 0.4 2.1 1 1 1 2 2 2 1 Myb DNA-binding like Rap1_C PF11626.8 EWM26309.1 - 0.0037 17.3 4.6 1 9.5 0.5 3.5 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 EWM26309.1 - 0.12 12.6 0.2 4.2 7.6 0.0 2.5 1 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 ABC_tran PF00005.27 EWM26310.1 - 3.8e-30 105.2 0.2 7.5e-30 104.2 0.2 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EWM26310.1 - 1.3e-24 86.9 12.1 2.3e-24 86.2 12.1 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 EWM26310.1 - 3e-09 37.1 0.0 2.5e-05 24.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_2 PF12679.7 EWM26310.1 - 0.0057 16.0 13.9 0.0057 16.0 13.9 1.7 2 0 0 2 2 2 1 ABC-2 family transporter protein SMC_N PF02463.19 EWM26310.1 - 0.0072 15.8 0.1 4.5 6.6 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EWM26310.1 - 0.012 15.3 0.6 0.031 14.0 0.6 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EWM26310.1 - 0.013 15.4 0.1 0.024 14.6 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 EWM26310.1 - 0.16 12.4 1.8 0.17 12.3 0.4 1.7 2 0 0 2 2 2 0 AAA domain VPS9 PF02204.18 EWM26311.1 - 3e-14 53.1 0.0 5.5e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain AAA_2 PF07724.14 EWM26312.1 - 4.3e-56 189.7 0.0 3.1e-52 177.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EWM26312.1 - 8.6e-35 118.8 0.4 8.6e-35 118.8 0.4 2.4 2 0 0 2 2 2 1 AAA lid domain AAA PF00004.29 EWM26312.1 - 3.7e-25 88.9 0.0 8e-13 49.0 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EWM26312.1 - 7.8e-18 64.8 1.0 1.8e-12 47.4 0.0 3.4 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.9 EWM26312.1 - 8.1e-18 64.3 0.1 3.3e-17 62.3 0.1 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.6 EWM26312.1 - 3.8e-13 50.2 6.8 8.8e-06 26.2 0.1 5.2 4 2 1 6 6 4 2 AAA ATPase domain Clp_N PF02861.20 EWM26312.1 - 9.4e-12 44.9 5.0 9e-08 32.1 0.9 3.6 2 1 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_22 PF13401.6 EWM26312.1 - 4.2e-09 36.8 1.0 0.0012 19.2 0.0 4.7 3 2 0 3 3 3 2 AAA domain Sigma54_activat PF00158.26 EWM26312.1 - 5.6e-08 32.7 0.1 1.5e-05 24.8 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain ATPase_2 PF01637.18 EWM26312.1 - 1.4e-07 31.7 0.4 0.32 10.9 0.0 4.1 2 2 0 4 4 4 2 ATPase domain predominantly from Archaea AAA_7 PF12775.7 EWM26312.1 - 3.1e-07 30.1 0.0 0.0013 18.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 EWM26312.1 - 9.6e-07 28.7 0.0 0.0069 16.1 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 EWM26312.1 - 1.7e-06 28.1 0.0 0.083 12.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EWM26312.1 - 2.4e-06 27.1 0.2 0.05 13.0 0.1 3.4 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI TniB PF05621.11 EWM26312.1 - 6.7e-06 25.6 0.2 0.11 11.9 0.0 4.2 3 1 0 3 3 3 1 Bacterial TniB protein RNA_helicase PF00910.22 EWM26312.1 - 4.6e-05 23.8 0.1 0.11 12.9 0.0 3.2 3 0 0 3 3 3 1 RNA helicase AAA_18 PF13238.6 EWM26312.1 - 8.1e-05 23.2 0.1 0.084 13.4 0.0 3.2 2 1 1 3 3 3 1 AAA domain NACHT PF05729.12 EWM26312.1 - 0.0001 22.2 0.0 0.41 10.5 0.0 3.0 3 0 0 3 3 2 2 NACHT domain DNA_pol3_delta2 PF13177.6 EWM26312.1 - 0.0001 22.1 0.0 0.00034 20.4 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit RuvB_N PF05496.12 EWM26312.1 - 0.00015 21.5 2.0 0.73 9.6 0.0 4.3 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_23 PF13476.6 EWM26312.1 - 0.00016 22.2 1.2 1.7 9.1 0.9 3.5 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 EWM26312.1 - 0.00035 20.2 0.1 0.32 10.6 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 EWM26312.1 - 0.00047 19.9 0.0 0.092 12.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 EWM26312.1 - 0.0011 19.1 0.0 0.98 9.6 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 EWM26312.1 - 0.0016 18.6 0.0 0.16 12.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain Torsin PF06309.11 EWM26312.1 - 0.0017 18.4 0.0 0.0041 17.2 0.0 1.6 1 0 0 1 1 1 1 Torsin TsaE PF02367.17 EWM26312.1 - 0.0056 16.7 0.0 2.3 8.2 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 EWM26312.1 - 0.012 15.6 0.0 0.48 10.4 0.0 3.1 4 0 0 4 4 3 0 Type III restriction enzyme, res subunit RsgA_GTPase PF03193.16 EWM26312.1 - 0.014 15.4 0.0 7.8 6.4 0.0 2.8 2 0 0 2 2 2 0 RsgA GTPase AAA_3 PF07726.11 EWM26312.1 - 0.014 15.2 0.1 7.1 6.5 0.0 3.8 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EWM26312.1 - 0.019 15.2 0.8 11 6.2 0.0 3.8 3 1 0 3 3 3 0 AAA domain ABC_tran PF00005.27 EWM26312.1 - 0.047 14.2 0.1 7.7 7.0 0.0 3.3 3 0 0 3 3 3 0 ABC transporter AAA_19 PF13245.6 EWM26312.1 - 0.063 13.6 0.0 13 6.1 0.0 3.2 3 0 0 3 3 2 0 AAA domain Bac_DnaA PF00308.18 EWM26312.1 - 0.076 12.8 0.5 4.4 7.1 0.0 3.0 3 0 0 3 3 3 0 Bacterial dnaA protein SRP54 PF00448.22 EWM26312.1 - 0.13 11.9 0.3 3.7 7.1 0.0 3.0 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain ImmE5 PF11480.8 EWM26312.1 - 0.17 12.4 0.0 0.4 11.2 0.0 1.6 1 0 0 1 1 1 0 Colicin-E5 Imm protein BLOC1_2 PF10046.9 EWM26312.1 - 0.18 12.1 3.6 1 9.7 0.5 3.2 3 1 1 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Flavoprotein PF02441.19 EWM26313.1 - 5.5e-48 162.7 0.0 6.4e-48 162.5 0.0 1.0 1 0 0 1 1 1 1 Flavoprotein UCR_Fe-S_N PF10399.9 EWM26313.1 - 0.073 12.4 0.5 0.13 11.6 0.5 1.4 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal SQS_PSY PF00494.19 EWM26314.1 - 3.6e-39 134.8 0.1 3.6e-39 134.8 0.1 1.4 2 0 0 2 2 2 1 Squalene/phytoene synthase NUDIX PF00293.28 EWM26314.1 - 1.1e-19 70.7 0.0 2.5e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain ACT_5 PF13710.6 EWM26316.1 - 4.8 7.1 22.5 9.5 6.2 0.2 7.2 8 0 0 8 8 8 0 ACT domain ABC_tran PF00005.27 EWM26317.1 - 5.9e-24 85.1 0.1 1.2e-21 77.7 0.0 3.1 2 1 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EWM26317.1 - 3.8e-08 33.0 0.0 2.5e-07 30.4 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Chromo PF00385.24 EWM26317.1 - 5.8e-08 32.5 1.2 1.6e-07 31.1 1.2 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_21 PF13304.6 EWM26317.1 - 0.00017 21.5 4.8 0.017 15.0 0.4 2.8 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 EWM26317.1 - 0.0022 18.1 0.9 0.03 14.4 0.0 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain MMR_HSR1 PF01926.23 EWM26317.1 - 0.016 15.3 0.2 0.064 13.3 0.0 2.2 3 0 0 3 3 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 EWM26317.1 - 0.022 14.5 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EWM26317.1 - 0.035 13.9 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 EWM26317.1 - 0.042 14.0 0.0 0.09 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EWM26317.1 - 0.067 13.6 0.3 0.87 10.0 0.0 2.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EWM26317.1 - 0.069 13.0 0.8 0.15 11.9 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 EWM26317.1 - 0.09 13.1 0.0 0.38 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EWM26317.1 - 0.096 12.9 0.0 0.54 10.5 0.0 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.23 EWM26317.1 - 0.13 12.3 0.1 0.13 12.3 0.1 2.3 2 1 0 2 2 2 0 Dynamin family AAA_16 PF13191.6 EWM26317.1 - 0.16 12.3 0.0 0.36 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_15 PF13175.6 EWM26317.1 - 0.26 11.0 9.1 0.1 12.3 0.2 2.8 3 1 0 3 3 3 0 AAA ATPase domain Sigma70_r1_1 PF03979.14 EWM26317.1 - 0.28 11.3 9.3 0.33 11.0 2.5 3.0 3 0 0 3 3 2 0 Sigma-70 factor, region 1.1 Dynein_light PF01221.18 EWM26319.1 - 3.1e-24 85.1 0.4 3.4e-24 85.0 0.4 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 WD40 PF00400.32 EWM26320.1 - 6.5e-26 90.1 20.1 0.0014 19.4 0.2 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM26320.1 - 1.2e-05 25.6 0.0 0.18 12.1 0.0 4.3 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EWM26320.1 - 6.2e-05 23.4 4.5 6.9 7.3 0.0 5.8 5 1 0 5 5 5 1 PQQ-like domain Nup160 PF11715.8 EWM26320.1 - 0.0082 14.8 0.1 2.8 6.5 0.0 3.0 1 1 2 3 3 3 1 Nucleoporin Nup120/160 Frtz PF11768.8 EWM26320.1 - 0.052 11.9 0.0 6.3 5.0 0.0 2.3 2 1 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz FtsJ PF01728.19 EWM26321.1 - 8.7e-68 227.9 0.0 1e-67 227.7 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Gelsolin PF00626.22 EWM26322.1 - 3.3e-46 155.1 0.0 1.7e-10 40.7 0.0 6.9 7 1 0 7 7 7 6 Gelsolin repeat VHP PF02209.19 EWM26322.1 - 9.6e-13 48.0 0.7 1.9e-12 47.0 0.7 1.5 1 0 0 1 1 1 1 Villin headpiece domain PAC4 PF16093.5 EWM26322.1 - 0.0083 16.3 0.0 0.22 11.7 0.0 3.3 3 0 0 3 3 3 1 Proteasome assembly chaperone 4 Sld5 PF05916.11 EWM26323.1 - 3.5e-20 72.5 0.1 5.2e-20 71.9 0.1 1.3 1 0 0 1 1 1 1 GINS complex protein stn_TNFRSF12A PF12191.8 EWM26325.1 - 0.14 12.4 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain IATP PF04568.12 EWM26325.1 - 2.2 8.8 4.0 3.1 8.3 4.0 1.2 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP MRI PF15325.6 EWM26325.1 - 2.6 9.2 5.4 3.7 8.7 5.4 1.2 1 0 0 1 1 1 0 Modulator of retrovirus infection HMG_box PF00505.19 EWM26326.1 - 1.1e-15 57.7 12.6 1e-14 54.7 1.8 2.5 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 EWM26326.1 - 1.5e-11 44.7 2.2 1.5e-11 44.7 2.2 3.0 2 1 1 3 3 3 2 HMG-box domain ABC_membrane PF00664.23 EWM26327.1 - 8.1e-61 206.1 11.4 4.5e-31 108.5 0.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EWM26327.1 - 3.3e-43 147.5 0.0 2.2e-26 93.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 EWM26327.1 - 1.3e-08 34.4 0.4 0.00071 19.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EWM26327.1 - 2.2e-06 27.7 3.7 0.064 13.0 0.3 4.2 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EWM26327.1 - 3.9e-06 26.5 0.0 0.04 13.3 0.0 3.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.23 EWM26327.1 - 1e-05 25.6 0.1 0.14 12.3 0.0 2.3 2 0 0 2 2 2 2 Dynamin family AAA_16 PF13191.6 EWM26327.1 - 6e-05 23.5 0.1 0.023 15.1 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 EWM26327.1 - 0.00011 21.4 0.1 0.0098 15.0 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein MMR_HSR1 PF01926.23 EWM26327.1 - 0.00012 22.1 1.8 0.02 14.9 0.4 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 EWM26327.1 - 0.00039 21.0 0.0 1.6 9.2 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EWM26327.1 - 0.0037 17.5 0.8 3.3 8.0 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EWM26327.1 - 0.018 15.6 0.0 8.2 7.0 0.0 2.7 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EWM26327.1 - 0.035 13.5 0.3 0.42 9.9 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_ATPase PF09818.9 EWM26327.1 - 0.036 12.9 0.1 1.3 7.7 0.0 2.6 3 0 0 3 3 3 0 Predicted ATPase of the ABC class DUF87 PF01935.17 EWM26327.1 - 0.04 14.0 0.2 0.079 13.0 0.2 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 EWM26327.1 - 0.08 12.8 0.9 14 5.5 0.4 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_33 PF13671.6 EWM26327.1 - 0.14 12.4 0.0 25 5.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EWM26327.1 - 0.14 11.7 0.9 8 6.0 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 EWM26327.1 - 0.15 11.6 0.6 4.2 6.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 EWM26327.1 - 0.2 11.5 0.2 15 5.5 0.0 3.0 3 0 0 3 3 3 0 NTPase 3HCDH_N PF02737.18 EWM26329.1 - 2.2e-55 187.3 0.1 3e-55 186.9 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EWM26329.1 - 1.9e-28 98.9 0.0 8.1e-28 96.9 0.0 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EWM26329.1 - 0.0031 17.7 0.8 0.0059 16.8 0.8 1.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_2 PF07992.14 EWM26329.1 - 0.01 15.1 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF2680 PF10925.8 EWM26329.1 - 0.013 15.5 0.7 0.091 12.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) UDPG_MGDP_dh_N PF03721.14 EWM26329.1 - 0.015 14.9 0.2 0.024 14.2 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 EWM26329.1 - 0.1 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EWM26329.1 - 0.24 12.0 3.2 1.3 9.7 3.2 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent zf-CCCH PF00642.24 EWM26330.1 - 1.5e-12 47.0 14.6 2.8e-06 27.1 3.4 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EWM26330.1 - 4.8e-06 26.5 12.8 0.0068 16.4 3.3 2.6 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 EWM26330.1 - 3.8e-05 24.3 1.2 0.19 12.4 0.2 2.4 2 0 0 2 2 2 2 Torus domain RRM_1 PF00076.22 EWM26330.1 - 6.7e-05 22.6 0.1 0.00011 21.9 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_4 PF18044.1 EWM26330.1 - 0.00095 18.9 14.7 0.0053 16.5 2.9 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger Tachystatin_B PF11478.8 EWM26330.1 - 0.0039 17.1 3.1 0.013 15.4 0.9 2.8 2 0 0 2 2 2 1 Antimicrobial chitin binding protein tachystatin B zf-CCCH_3 PF15663.5 EWM26330.1 - 0.075 13.3 1.9 5.9 7.2 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger containing family TerC PF03741.16 EWM26331.1 - 5.4e-51 172.8 2.9 7.4e-51 172.4 2.9 1.2 1 0 0 1 1 1 1 Integral membrane protein TerC family Na_trans_assoc PF06512.13 EWM26332.1 - 0.024 14.9 1.4 0.024 14.9 1.4 2.0 2 0 0 2 2 2 0 Sodium ion transport-associated BSP_II PF05432.11 EWM26332.1 - 0.04 13.6 9.0 0.027 14.2 5.9 2.0 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Ribosomal_60s PF00428.19 EWM26332.1 - 0.16 12.6 13.0 0.12 12.9 8.2 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Nop14 PF04147.12 EWM26332.1 - 0.4 8.9 4.9 0.53 8.4 4.9 1.1 1 0 0 1 1 1 0 Nop14-like family WRNPLPNID PF15017.6 EWM26332.1 - 0.85 10.5 10.6 6.9 7.6 8.3 2.6 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box vMSA PF00695.19 EWM26332.1 - 1.2 8.2 3.7 2.4 7.2 3.7 1.5 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus PI3K_1B_p101 PF10486.9 EWM26332.1 - 3 5.5 6.8 4.4 5.0 6.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DNA_pol_phi PF04931.13 EWM26332.1 - 5 5.1 6.3 7.4 4.5 6.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi ABC_tran PF00005.27 EWM26333.1 - 4.7e-13 49.8 0.0 1.8e-12 47.9 0.0 2.0 1 1 0 1 1 1 1 ABC transporter HEAT PF02985.22 EWM26333.1 - 1.9e-07 30.7 1.9 0.002 18.2 0.0 5.2 5 0 0 5 5 4 1 HEAT repeat AAA_21 PF13304.6 EWM26333.1 - 2.3e-06 27.6 0.0 0.00098 19.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Cnd1 PF12717.7 EWM26333.1 - 0.00012 22.2 0.5 0.00062 19.9 0.2 2.1 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EWM26333.1 - 0.0037 17.7 6.8 3.5 8.2 0.0 5.0 5 0 0 5 5 5 1 HEAT-like repeat AAA_23 PF13476.6 EWM26333.1 - 0.004 17.7 0.0 0.023 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EWM26333.1 - 0.004 16.9 0.0 0.0075 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_27 PF13514.6 EWM26333.1 - 0.0051 16.4 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain DCB PF16213.5 EWM26333.1 - 0.0077 15.9 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 HEAT_2 PF13646.6 EWM26333.1 - 0.014 15.8 0.8 0.14 12.5 0.0 2.9 2 1 1 3 3 3 0 HEAT repeats DUF1981 PF09324.10 EWM26333.1 - 0.019 14.8 0.1 0.11 12.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) ATPase_2 PF01637.18 EWM26333.1 - 0.023 14.6 0.0 0.065 13.1 0.0 1.7 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Adaptin_N PF01602.20 EWM26333.1 - 0.035 12.7 0.4 0.059 11.9 0.4 1.5 1 1 0 1 1 1 0 Adaptin N terminal region UTP15_C PF09384.10 EWM26333.1 - 0.042 13.5 0.1 0.27 10.9 0.0 2.4 2 2 0 2 2 2 0 UTP15 C terminal AAA_14 PF13173.6 EWM26333.1 - 0.042 13.9 0.0 0.4 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Vac14_Fab1_bd PF12755.7 EWM26333.1 - 0.048 14.3 0.0 0.29 11.7 0.0 2.3 2 1 0 2 2 2 0 Vacuolar 14 Fab1-binding region Ipi1_N PF12333.8 EWM26333.1 - 0.072 13.7 0.1 37 5.0 0.0 3.3 2 1 1 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation PduV-EutP PF10662.9 EWM26333.1 - 0.077 12.7 0.0 0.24 11.1 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 EWM26333.1 - 0.086 12.9 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.29 EWM26333.1 - 0.12 12.8 0.0 0.72 10.3 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF326 PF03860.16 EWM26333.1 - 1.2 9.2 5.8 2.4 8.3 0.6 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF326) UPF0640 PF15114.6 EWM26334.1 - 4.7e-05 23.1 0.0 8.8e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 Uncharacterised protein family UPF0640 TIP41 PF04176.13 EWM26335.1 - 1.2e-43 148.6 0.0 1.8e-43 148.0 0.0 1.3 1 0 0 1 1 1 1 TIP41-like family Gelsolin PF00626.22 EWM26335.1 - 0.19 11.7 0.0 0.41 10.6 0.0 1.6 1 0 0 1 1 1 0 Gelsolin repeat Sugar_tr PF00083.24 EWM26336.1 - 9.1e-25 87.4 10.3 1.9e-14 53.4 0.0 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EWM26336.1 - 2.4e-24 85.9 32.1 3.9e-24 85.2 32.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily YtpI PF14007.6 EWM26336.1 - 0.073 13.2 3.8 2.7 8.2 0.8 2.8 2 0 0 2 2 2 0 YtpI-like protein PP2C PF00481.21 EWM26338.1 - 3.3e-33 115.4 0.0 6.5e-33 114.4 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EWM26338.1 - 0.00084 19.3 0.0 0.081 12.8 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) SNARE_assoc PF09335.11 EWM26339.1 - 1.5e-14 54.5 4.3 1.5e-14 54.5 4.3 3.1 3 1 0 3 3 3 1 SNARE associated Golgi protein DUF2207 PF09972.9 EWM26339.1 - 0.18 10.5 2.6 5 5.8 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) APG12 PF04110.13 EWM26340.1 - 4.4e-23 81.5 0.0 6.6e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 EWM26340.1 - 0.00017 21.8 0.0 0.00023 21.3 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Med3 PF11593.8 EWM26340.1 - 1.8 7.6 7.8 2.4 7.3 7.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ribosomal_L23eN PF03939.13 EWM26341.1 - 0.033 14.4 0.5 0.061 13.5 0.5 1.3 1 0 0 1 1 1 0 Ribosomal protein L23, N-terminal domain FAD_binding_3 PF01494.19 EWM26342.1 - 6.3e-22 78.3 0.9 3.6e-11 42.9 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EWM26342.1 - 4.7e-10 39.6 0.2 4.4e-07 29.8 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EWM26342.1 - 8.7e-07 29.1 0.2 4.1e-06 26.9 0.3 2.2 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EWM26342.1 - 1.1e-06 28.1 0.2 3.8e-05 23.1 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EWM26342.1 - 3.7e-05 22.9 0.3 0.0042 16.2 0.2 2.7 3 0 0 3 3 3 1 Lycopene cyclase protein SE PF08491.10 EWM26342.1 - 9.2e-05 21.6 0.0 0.0002 20.5 0.0 1.5 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_2 PF00890.24 EWM26342.1 - 9.8e-05 21.6 2.1 0.0002 20.6 2.1 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EWM26342.1 - 0.00013 22.4 0.3 0.00043 20.8 0.1 2.0 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EWM26342.1 - 0.00022 20.2 0.3 0.18 10.6 0.1 3.0 3 0 0 3 3 3 1 Tryptophan halogenase HI0933_like PF03486.14 EWM26342.1 - 0.002 16.9 0.6 0.0037 16.0 0.6 1.4 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.24 EWM26342.1 - 0.004 16.5 0.2 0.5 9.6 0.1 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 EWM26342.1 - 0.0043 16.3 0.1 0.008 15.4 0.1 1.4 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 EWM26342.1 - 0.0066 15.8 1.7 0.023 14.0 0.3 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 EWM26342.1 - 0.0077 15.5 0.1 0.023 14.0 0.1 1.7 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EWM26342.1 - 0.0089 16.0 0.4 2.8 7.9 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.22 EWM26342.1 - 0.025 13.7 0.4 0.038 13.1 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.16 EWM26342.1 - 0.038 13.6 1.0 0.096 12.3 0.5 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 EWM26342.1 - 0.043 13.7 0.8 0.075 12.9 0.8 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 EWM26342.1 - 0.066 12.8 0.3 0.12 11.9 0.3 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 EWM26342.1 - 0.079 12.3 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MaoC_dehydrat_N PF13452.6 EWM26342.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 N-terminal half of MaoC dehydratase Mito_carr PF00153.27 EWM26343.1 - 8e-61 202.0 2.1 8.5e-20 70.5 0.0 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein HTH_28 PF13518.6 EWM26343.1 - 0.072 13.2 0.2 0.32 11.2 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain Aldolase PF01081.19 EWM26345.1 - 9.3e-20 70.9 0.4 1.6e-17 63.6 0.2 2.1 2 0 0 2 2 2 2 KDPG and KHG aldolase 3HCDH_N PF02737.18 EWM26347.1 - 6.5e-57 192.3 0.8 6.5e-57 192.3 0.8 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 EWM26347.1 - 1.3e-36 126.2 0.0 4.1e-36 124.6 0.0 1.7 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 EWM26347.1 - 1.8e-27 95.8 0.0 3.2e-19 69.3 0.0 2.7 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 EWM26347.1 - 4.9e-21 75.6 1.1 9.4e-21 74.6 0.0 1.9 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase NAD_binding_7 PF13241.6 EWM26347.1 - 3.2e-05 24.3 0.2 7.8e-05 23.1 0.2 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 EWM26347.1 - 5.8e-05 22.5 0.3 0.00011 21.6 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EWM26347.1 - 0.0018 18.8 2.1 0.0046 17.5 2.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 EWM26347.1 - 0.0027 17.9 0.1 0.0082 16.3 0.1 1.9 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DFP PF04127.15 EWM26347.1 - 0.0057 16.5 0.8 0.0057 16.5 0.8 2.0 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein DAO PF01266.24 EWM26347.1 - 0.037 13.6 0.5 0.06 12.9 0.5 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase F420_oxidored PF03807.17 EWM26347.1 - 0.13 12.9 0.6 0.36 11.5 0.6 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Exo_endo_phos PF03372.23 EWM26348.1 - 1.6e-08 34.4 0.0 2.7e-08 33.6 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PFK PF00365.20 EWM26350.1 - 3.5e-59 200.5 0.1 4.6e-59 200.1 0.1 1.1 1 0 0 1 1 1 1 Phosphofructokinase LSDAT_euk PF18139.1 EWM26350.1 - 0.084 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 SLOG in TRPM vATP-synt_AC39 PF01992.16 EWM26351.1 - 4.1e-62 210.6 0.0 5e-62 210.4 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit PIP5K PF01504.18 EWM26352.1 - 1.4e-54 185.2 0.0 2.6e-54 184.3 0.0 1.4 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase zf-CSL PF05207.13 EWM26353.1 - 5.5e-21 74.1 0.9 7.5e-21 73.6 0.9 1.2 1 0 0 1 1 1 1 CSL zinc finger DUF4539 PF15072.6 EWM26354.1 - 3.7e-14 52.5 0.0 6.1e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) Porin_3 PF01459.22 EWM26355.1 - 0.0012 18.4 0.0 0.0014 18.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin Arf PF00025.21 EWM26356.1 - 4.8e-61 205.2 0.3 6e-61 204.9 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EWM26356.1 - 2.1e-12 47.3 0.0 3.3e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EWM26356.1 - 2.5e-12 46.7 0.0 3.3e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EWM26356.1 - 5.4e-12 45.5 0.2 2.1e-10 40.3 0.1 2.2 1 1 1 2 2 2 1 G-protein alpha subunit SRPRB PF09439.10 EWM26356.1 - 2.8e-09 36.7 0.0 3.8e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EWM26356.1 - 2.1e-08 33.8 0.0 2.9e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EWM26356.1 - 3.9e-07 30.1 0.0 6.5e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 EWM26356.1 - 2.1 7.9 4.7 20 4.7 0.2 2.8 2 1 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain FAD_binding_4 PF01565.23 EWM26357.1 - 4.4e-12 45.9 0.1 8.3e-12 45.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 EWM26357.1 - 0.0029 17.5 0.2 0.0061 16.4 0.2 1.6 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase Ribosomal_S3_C PF00189.20 EWM26358.1 - 4.2e-25 88.1 2.3 1.5e-24 86.3 2.4 1.8 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 EWM26358.1 - 3.6e-10 39.5 0.1 6.3e-10 38.7 0.1 1.4 1 0 0 1 1 1 1 KH domain Ribosomal_L6 PF00347.23 EWM26358.1 - 0.02 15.5 0.2 6.3 7.6 0.0 2.8 3 0 0 3 3 3 0 Ribosomal protein L6 Aldedh PF00171.22 EWM26359.1 - 3.4e-168 559.9 0.2 4e-168 559.7 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cecropin PF00272.19 EWM26359.1 - 0.13 12.0 1.0 0.35 10.6 0.1 2.3 2 0 0 2 2 2 0 Cecropin family DEAD PF00270.29 EWM26360.1 - 2.5e-43 147.9 0.0 3.9e-43 147.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EWM26360.1 - 4.1e-22 78.6 0.0 1.3e-21 77.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EWM26360.1 - 1.4e-19 70.1 0.1 3.1e-19 69.0 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EWM26360.1 - 2.1e-06 27.9 0.0 5.6e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HSP90 PF00183.18 EWM26360.1 - 3.5 6.4 5.5 22 3.8 6.7 1.6 2 0 0 2 2 2 0 Hsp90 protein p450 PF00067.22 EWM26362.1 - 8.2e-76 255.6 0.0 2.7e-60 204.4 0.0 3.2 2 1 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 EWM26363.1 - 7.7e-76 255.7 0.0 2.6e-60 204.5 0.0 3.2 2 1 0 2 2 2 2 Cytochrome P450 Lyase_1 PF00206.20 EWM26364.1 - 2.3e-111 372.2 0.0 3.5e-111 371.5 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 EWM26364.1 - 1.2e-25 89.7 0.7 1.3e-24 86.3 0.4 2.5 2 0 0 2 2 2 1 Fumarase C C-terminus Methyltransf_15 PF09445.10 EWM26365.1 - 2.8e-24 85.5 0.0 4.2e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 EWM26365.1 - 8.3e-08 32.1 0.0 1.4e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 EWM26365.1 - 6.1e-06 26.1 0.0 9.1e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltr_RsmB-F PF01189.17 EWM26365.1 - 0.00011 22.0 0.0 0.00018 21.2 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F MethyltransfD12 PF02086.15 EWM26365.1 - 0.021 14.5 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Peptidase_C80 PF11713.8 EWM26365.1 - 0.04 14.2 0.0 0.066 13.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase C80 family RQC PF09382.10 EWM26365.1 - 0.12 12.2 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 RQC domain MTS PF05175.14 EWM26365.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain MSA-2c PF12238.8 EWM26365.1 - 9 6.2 7.2 14 5.6 7.2 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c tRNA_U5-meth_tr PF05958.11 EWM26366.1 - 3.3e-05 23.1 0.1 0.00041 19.5 0.0 2.4 2 1 1 3 3 3 1 tRNA (Uracil-5-)-methyltransferase UPF0020 PF01170.18 EWM26366.1 - 0.0006 19.6 0.1 0.0013 18.4 0.1 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 DUF963 PF06131.11 EWM26366.1 - 0.0028 17.0 1.8 0.0094 15.4 1.8 2.0 1 0 0 1 1 1 1 Schizosaccharomyces pombe repeat of unknown function (DUF963) Methyltransf_4 PF02390.17 EWM26366.1 - 0.0061 16.1 0.0 0.067 12.6 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.6 EWM26366.1 - 0.0064 17.2 1.1 1.8 9.3 0.2 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM26366.1 - 0.0073 16.1 0.4 1.3 8.9 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain DUF1388 PF07142.12 EWM26366.1 - 0.0091 15.9 6.7 0.021 14.8 6.7 1.7 1 0 0 1 1 1 1 Repeat of unknown function (DUF1388) MTS PF05175.14 EWM26366.1 - 0.15 11.6 0.6 0.51 9.9 0.1 1.9 2 0 0 2 2 2 0 Methyltransferase small domain Peptidase_M48 PF01435.18 EWM26367.1 - 6.2e-36 124.0 0.0 9.2e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_C48 PF02902.19 EWM26369.1 - 2.5e-33 115.7 0.1 3.9e-33 115.1 0.1 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Methyltransf_32 PF13679.6 EWM26370.1 - 2.1e-13 50.6 2.0 1.6e-12 47.7 2.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM26370.1 - 6.4e-11 42.3 0.0 1.2e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TRM13 PF05206.14 EWM26370.1 - 2.4e-09 37.1 0.1 4.8e-09 36.1 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase TRM13 Methyltransf_25 PF13649.6 EWM26370.1 - 9.7e-09 35.8 0.0 2.3e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EWM26370.1 - 9.8e-07 28.4 0.0 2.2e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.12 EWM26370.1 - 1.3e-05 25.8 0.0 3.5e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EWM26370.1 - 0.00027 20.5 0.0 0.00044 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EWM26370.1 - 0.00047 20.8 0.0 0.0013 19.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EWM26370.1 - 0.0035 17.2 0.0 0.0071 16.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EWM26370.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase DUF938 PF06080.12 EWM26370.1 - 0.18 11.5 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) TLD PF07534.16 EWM26371.1 - 5.3e-33 114.2 0.6 8.4e-33 113.5 0.6 1.3 1 0 0 1 1 1 1 TLD RhoGAP PF00620.27 EWM26371.1 - 3.4e-11 43.2 0.0 1.2e-10 41.4 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain RUN PF02759.19 EWM26371.1 - 1.6e-07 31.4 0.0 4.8e-07 29.8 0.0 1.9 1 1 0 1 1 1 1 RUN domain ELMO_CED12 PF04727.13 EWM26371.1 - 1.4e-06 28.5 0.0 4e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 ELMO/CED-12 family Ubie_methyltran PF01209.18 EWM26372.1 - 1.2e-31 109.9 0.0 1.5e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EWM26372.1 - 1.5e-13 51.3 0.1 3.4e-13 50.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM26372.1 - 4e-11 43.4 0.0 8.5e-11 42.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM26372.1 - 6.6e-08 32.5 0.0 8.8e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EWM26372.1 - 3.5e-07 30.9 0.0 5.9e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EWM26372.1 - 0.00012 22.0 0.0 0.00017 21.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EWM26372.1 - 0.00021 20.7 0.1 0.014 14.7 0.0 2.0 1 1 1 2 2 2 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 EWM26372.1 - 0.022 14.5 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Gram_pos_anchor PF00746.21 EWM26372.1 - 0.21 11.6 1.3 0.55 10.2 0.9 2.0 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Metallophos PF00149.28 EWM26373.1 - 4.1e-36 125.4 0.0 5.3e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 EWM26373.1 - 0.092 12.4 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain DUF5341 PF17276.2 EWM26373.1 - 0.094 12.9 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5341) STPPase_N PF16891.5 EWM26373.1 - 0.13 12.7 0.5 0.13 12.7 0.5 1.9 2 0 0 2 2 2 0 Serine-threonine protein phosphatase N-terminal domain tRNA-synt_1 PF00133.22 EWM26374.1 - 4.1e-213 709.0 0.0 6.3e-213 708.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EWM26374.1 - 2.5e-24 86.0 0.0 3.8e-23 82.1 0.0 2.2 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EWM26374.1 - 7.7e-15 54.5 0.1 9.2e-05 21.4 0.1 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EWM26374.1 - 7.8e-06 25.4 0.0 1.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Sec3_C PF09763.9 EWM26378.1 - 4.4e-33 114.7 0.0 1.2e-19 70.2 0.0 4.1 4 0 0 4 4 4 4 Exocyst complex component Sec3 Nsp1_C PF05064.13 EWM26378.1 - 0.44 10.4 2.5 1.6 8.5 2.5 1.9 1 0 0 1 1 1 0 Nsp1-like C-terminal region YabA PF06156.13 EWM26378.1 - 0.78 10.4 3.7 2.7 8.7 1.5 2.3 2 0 0 2 2 2 0 Initiation control protein YabA Spectrin PF00435.21 EWM26378.1 - 2.9 8.4 7.4 8.6 6.9 3.6 2.9 2 0 0 2 2 2 0 Spectrin repeat Spc7 PF08317.11 EWM26378.1 - 3.1 6.6 10.3 2.8 6.7 2.4 2.5 3 0 0 3 3 3 0 Spc7 kinetochore protein DHR10 PF18595.1 EWM26378.1 - 3.1 7.9 9.0 0.13 12.3 2.9 1.8 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain PHD_2 PF13831.6 EWM26379.1 - 1.3e-07 31.0 10.5 2.1e-07 30.4 8.6 2.3 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 EWM26379.1 - 5.9e-06 26.1 10.4 5.9e-06 26.1 10.4 3.7 4 0 0 4 4 4 1 PHD-finger zf-HC5HC2H PF13771.6 EWM26379.1 - 0.00029 21.0 2.1 0.00029 21.0 2.1 3.3 3 0 0 3 3 3 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EWM26379.1 - 0.058 13.6 25.2 0.032 14.4 2.4 4.4 4 0 0 4 4 4 0 PHD-zinc-finger like domain PTS_2-RNA PF01885.16 EWM26379.1 - 0.1 12.7 0.1 0.16 12.0 0.1 1.2 1 0 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family Orthopox_A5L PF06193.11 EWM26379.1 - 0.52 9.7 5.7 0.86 9.0 5.7 1.2 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like FTZ PF03867.14 EWM26379.1 - 1.1 8.7 2.8 2.1 7.8 2.8 1.4 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region Rrn6 PF10214.9 EWM26379.1 - 3.9 5.8 6.2 6.2 5.2 6.2 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Nipped-B_C PF12830.7 EWM26380.1 - 3.9e-45 154.1 0.0 3.6e-43 147.7 0.0 2.6 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 EWM26380.1 - 1.4e-08 34.8 0.8 1.3e-05 25.4 0.1 2.7 2 0 0 2 2 2 2 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 EWM26380.1 - 2.3e-05 24.5 0.0 0.24 11.4 0.0 2.8 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EWM26380.1 - 0.00052 20.3 5.0 0.81 10.1 0.1 4.0 3 1 1 4 4 4 3 HEAT repeats HEAT_EZ PF13513.6 EWM26380.1 - 0.64 10.6 8.8 20 5.8 0.0 5.6 6 0 0 6 6 6 0 HEAT-like repeat HEAT PF02985.22 EWM26380.1 - 4.8 7.7 14.0 15 6.2 0.0 5.8 7 0 0 7 7 7 0 HEAT repeat CoA_binding PF02629.19 EWM26381.1 - 9.2e-27 93.6 0.5 2.5e-26 92.2 0.5 1.8 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.19 EWM26381.1 - 3.8e-25 88.5 0.1 5.9e-25 87.9 0.1 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 EWM26381.1 - 1.4e-09 37.8 0.0 2.8e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EWM26381.1 - 0.00037 21.0 0.1 0.0016 18.9 0.0 2.1 2 0 0 2 2 2 1 CoA binding domain Abhydrolase_6 PF12697.7 EWM26382.1 - 7.9e-13 49.5 3.1 1.1e-12 49.0 3.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EWM26382.1 - 2e-10 40.7 0.2 4.5e-10 39.6 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EWM26382.1 - 5.4e-09 35.7 0.2 9.1e-09 34.9 0.1 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EWM26382.1 - 0.0065 16.2 0.0 3.4 7.3 0.0 2.2 2 0 0 2 2 2 2 PGAP1-like protein Thioesterase PF00975.20 EWM26382.1 - 0.0084 16.2 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain MFS_1 PF07690.16 EWM26383.1 - 2.6e-23 82.5 20.8 5.6e-13 48.5 3.9 2.8 3 0 0 3 3 3 2 Major Facilitator Superfamily RRM_2 PF04059.12 EWM26384.1 - 7.7e-46 154.2 0.6 1.5e-45 153.3 0.6 1.5 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 EWM26384.1 - 0.00037 20.2 0.1 0.37 10.6 0.2 3.8 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.15 EWM26384.1 - 0.0033 17.5 1.1 0.0045 17.0 0.1 1.8 2 0 0 2 2 2 1 Smg-4/UPF3 family BRAP2 PF07576.12 EWM26384.1 - 0.02 15.1 0.1 0.046 13.9 0.1 1.5 1 0 0 1 1 1 0 BRCA1-associated protein 2 RRM_2 PF04059.12 EWM26385.1 - 7.7e-46 154.2 0.6 1.5e-45 153.3 0.6 1.5 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 EWM26385.1 - 0.00037 20.2 0.1 0.37 10.6 0.2 3.8 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.15 EWM26385.1 - 0.0033 17.5 1.1 0.0045 17.0 0.1 1.8 2 0 0 2 2 2 1 Smg-4/UPF3 family BRAP2 PF07576.12 EWM26385.1 - 0.02 15.1 0.1 0.046 13.9 0.1 1.5 1 0 0 1 1 1 0 BRCA1-associated protein 2 SNF2_N PF00176.23 EWM26386.1 - 2.6e-51 174.4 0.1 3.8e-51 173.8 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EWM26386.1 - 2.2e-17 63.4 0.0 5e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AP2 PF00847.20 EWM26386.1 - 7.7e-08 32.5 3.3 0.0069 16.6 0.1 3.1 3 0 0 3 3 3 2 AP2 domain HDA2-3 PF11496.8 EWM26386.1 - 0.0054 15.9 0.0 0.018 14.2 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 EWM26386.1 - 0.0074 16.3 0.2 0.022 14.8 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 EWM26386.1 - 0.034 13.8 0.0 0.08 12.6 0.0 1.6 1 0 0 1 1 1 0 SWI2/SNF2 ATPase Myb_DNA-binding PF00249.31 EWM26386.1 - 0.043 14.0 0.0 8.4 6.7 0.0 3.4 3 0 0 3 3 3 0 Myb-like DNA-binding domain RRM_1 PF00076.22 EWM26387.1 - 6.9e-15 54.6 0.0 9.4e-15 54.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EWM26387.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif adh_short_C2 PF13561.6 EWM26388.1 - 4.4e-63 213.0 2.1 5.9e-62 209.3 2.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EWM26388.1 - 5.5e-12 45.5 0.0 1.5e-11 44.1 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase Enoyl_reductase PF12241.8 EWM26388.1 - 0.022 14.1 0.0 9.5 5.5 0.1 2.8 2 1 1 3 3 3 0 Trans-2-enoyl-CoA reductase catalytic region KR PF08659.10 EWM26388.1 - 0.054 13.4 0.1 0.084 12.8 0.1 1.4 1 0 0 1 1 1 0 KR domain Pkinase PF00069.25 EWM26389.1 - 1.1e-72 244.6 0.0 1.3e-72 244.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM26389.1 - 1.1e-43 149.4 0.0 1.4e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EWM26389.1 - 0.00017 21.0 0.0 0.00059 19.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EWM26389.1 - 0.034 12.9 0.0 0.056 12.2 0.0 1.5 1 1 0 1 1 1 0 Fungal protein kinase Inositol_P PF00459.25 EWM26390.1 - 1e-61 208.9 0.0 1.3e-61 208.6 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Porin_3 PF01459.22 EWM26391.1 - 0.0059 16.1 0.2 0.0064 16.0 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic porin Peptidase_C14 PF00656.22 EWM26392.1 - 3.9e-13 49.9 0.0 4.8e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Caspase domain zf-C2H2 PF00096.26 EWM26393.1 - 0.095 13.2 0.1 0.18 12.4 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type Beta-lactamase PF00144.24 EWM26394.1 - 9.5e-29 100.7 0.0 6.5e-28 97.9 0.0 2.1 1 1 0 1 1 1 1 Beta-lactamase DUF515 PF04415.12 EWM26394.1 - 6.6 5.0 5.0 9.1 4.5 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) ABM PF03992.16 EWM26395.1 - 0.00074 19.6 3.9 2.3 8.4 0.1 3.5 2 2 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Peptidase_C14 PF00656.22 EWM26396.1 - 2.2e-16 60.6 0.0 3e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Tocopherol_cycl PF14249.6 EWM26397.1 - 3.8e-07 29.5 0.1 0.007 15.5 0.1 3.2 3 0 0 3 3 3 3 Tocopherol cyclase DUF3446 PF11928.8 EWM26397.1 - 0.98 9.8 11.6 8.2 6.8 0.3 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain NosL PF05573.12 EWM26398.1 - 0.0084 16.5 0.0 0.013 15.8 0.0 1.3 1 0 0 1 1 1 1 NosL UvrD_C PF13361.6 EWM26399.1 - 4.3e-16 59.2 0.0 5.9e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 EWM26399.1 - 1.9e-07 30.8 0.1 0.015 15.1 0.1 2.4 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain Got1 PF04178.12 EWM26400.1 - 1.8e-27 96.0 12.9 3e-27 95.3 12.9 1.4 1 0 0 1 1 1 1 Got1/Sft2-like family Methyltransf_11 PF08241.12 EWM26403.1 - 4.6e-10 40.0 0.0 8.8e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM26403.1 - 7.1e-07 29.1 0.0 1.1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM26403.1 - 2.4e-06 28.2 0.0 4.7e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EWM26403.1 - 0.0012 18.3 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EWM26403.1 - 0.0022 18.7 0.0 0.0044 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EWM26403.1 - 0.019 14.8 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_29 PF03141.16 EWM26403.1 - 0.031 12.9 0.0 0.041 12.5 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Lyase_aromatic PF00221.19 EWM26403.1 - 0.24 10.0 0.0 0.31 9.6 0.0 1.1 1 0 0 1 1 1 0 Aromatic amino acid lyase Ribonuc_red_sm PF00268.21 EWM26406.1 - 1.5e-14 54.1 0.2 2.1e-14 53.7 0.2 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain PGK PF00162.19 EWM26407.1 - 2.3e-165 550.1 0.7 2.6e-165 549.9 0.7 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase ADH_zinc_N PF00107.26 EWM26407.1 - 0.014 15.4 0.5 4.7 7.2 0.0 3.0 3 0 0 3 3 3 0 Zinc-binding dehydrogenase Mur_ligase PF01225.25 EWM26407.1 - 0.069 13.5 0.2 1.1 9.6 0.0 2.7 3 0 0 3 3 3 0 Mur ligase family, catalytic domain PrpR_N PF06506.11 EWM26407.1 - 0.072 12.7 0.4 0.73 9.4 0.1 2.5 2 1 1 3 3 3 0 Propionate catabolism activator RsfS PF02410.15 EWM26409.1 - 8.1e-21 74.3 0.0 1.2e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation RsfS PF02410.15 EWM26410.1 - 8.9e-21 74.2 0.0 1.2e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation Methyltrans_RNA PF04452.14 EWM26412.1 - 3.7e-40 137.6 0.0 1.5e-38 132.4 0.0 2.2 1 1 0 1 1 1 1 RNA methyltransferase PT PF04886.12 EWM26413.1 - 7.4e-21 73.4 190.0 0.062 12.9 26.6 7.8 2 1 3 5 5 5 1 PT repeat RNase_PH PF01138.21 EWM26414.1 - 4.4e-22 79.0 0.2 1.3e-21 77.5 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EWM26414.1 - 1.4e-05 25.1 0.0 2.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Rad51 PF08423.11 EWM26416.1 - 0.0024 17.2 0.0 0.0028 16.9 0.0 1.0 1 0 0 1 1 1 1 Rad51 PLDc_2 PF13091.6 EWM26417.1 - 0.0083 16.0 0.0 1.4 8.8 0.0 2.6 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EWM26417.1 - 0.013 15.7 0.2 0.49 10.7 0.0 3.0 3 0 0 3 3 3 0 Phospholipase D Active site motif zf-Sec23_Sec24 PF04810.15 EWM26421.1 - 1.5e-17 63.4 7.7 2.1e-17 62.9 7.7 1.2 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.5 EWM26421.1 - 0.026 13.9 0.3 0.026 13.9 0.3 1.7 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DASH_Dad4 PF08650.10 EWM26424.1 - 0.0056 16.6 0.0 0.028 14.4 0.0 2.0 2 0 0 2 2 2 1 DASH complex subunit Dad4 Sec23_trunk PF04811.15 EWM26425.1 - 3.5e-16 59.5 0.0 3.9e-16 59.4 0.0 1.0 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain VWA_2 PF13519.6 EWM26425.1 - 0.089 13.5 0.0 0.11 13.1 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain Keratin_assoc PF09775.9 EWM26425.1 - 0.16 11.6 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 Keratinocyte-associated protein 2 Sec23_BS PF08033.12 EWM26428.1 - 3.6e-27 94.9 0.0 1.1e-26 93.4 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Sec23_trunk PF04811.15 EWM26428.1 - 2e-26 93.0 0.0 3e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EWM26428.1 - 1.6e-23 82.4 0.1 4e-23 81.2 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 EWM26428.1 - 8e-11 41.7 0.0 1.5e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat F_bP_aldolase PF01116.20 EWM26429.1 - 1.5e-75 254.3 0.3 2.6e-75 253.5 0.3 1.3 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II NBD_C PF17042.5 EWM26429.1 - 1.9e-36 126.1 0.0 5.6e-36 124.6 0.0 1.9 1 0 0 1 1 1 1 Nucleotide-binding C-terminal domain SBD_N PF07005.11 EWM26429.1 - 1.5e-19 70.6 0.2 2.1e-09 37.5 0.0 3.4 2 1 1 3 3 3 2 Sugar-binding N-terminal domain Thioredoxin PF00085.20 EWM26430.1 - 1e-18 67.2 0.0 1.6e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EWM26430.1 - 1.2e-05 25.5 0.0 3.1e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EWM26430.1 - 3e-05 23.9 0.0 4.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 EWM26430.1 - 0.0002 20.8 0.0 0.0003 20.3 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 EWM26430.1 - 0.00027 20.7 0.0 0.00042 20.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 EWM26430.1 - 0.0023 18.1 0.0 0.0042 17.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EWM26430.1 - 0.0025 18.2 0.1 0.0069 16.8 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 EWM26430.1 - 0.04 13.6 0.1 0.081 12.6 0.0 1.5 2 0 0 2 2 2 0 Redoxin Lipase_3 PF01764.25 EWM26431.1 - 2.8e-33 114.8 0.0 5e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 EWM26431.1 - 2.4e-05 23.7 0.0 4.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EWM26431.1 - 0.0012 19.0 0.0 0.0022 18.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 EWM26431.1 - 0.0016 19.1 0.1 0.0039 17.8 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 EWM26431.1 - 0.0029 17.2 0.0 0.1 12.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.20 EWM26431.1 - 0.018 14.7 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Cutinase PF01083.22 EWM26431.1 - 0.02 14.8 0.0 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 Cutinase LIDHydrolase PF10230.9 EWM26431.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Stealth_CR3 PF17102.5 EWM26433.1 - 5.8e-17 61.3 2.7 8.7e-17 60.8 2.7 1.3 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 EF-hand_1 PF00036.32 EWM26433.1 - 0.0075 15.7 0.3 0.021 14.4 0.3 1.7 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 EWM26433.1 - 0.033 13.7 2.3 0.038 13.5 0.9 1.8 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 EWM26433.1 - 0.11 13.0 0.0 0.24 11.9 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 EWM26433.1 - 0.12 12.4 0.1 0.29 11.2 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain DUF2781 PF10914.8 EWM26434.1 - 8.7e-40 136.5 16.1 1.1e-39 136.1 16.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Glycos_transf_1 PF00534.20 EWM26435.1 - 5.8e-15 55.2 0.0 1.7e-14 53.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EWM26435.1 - 2.7e-12 47.3 0.0 5.2e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EWM26435.1 - 4.7e-05 23.7 0.0 0.00012 22.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EWM26435.1 - 0.12 12.3 0.0 0.4 10.7 0.0 1.9 1 1 0 1 1 1 0 Glycosyltransferase Family 4 Lipase_GDSL PF00657.22 EWM26439.1 - 5e-07 29.9 0.0 6.6e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 EWM26439.1 - 0.0069 16.8 0.0 0.0095 16.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Ank_3 PF13606.6 EWM26440.1 - 0.039 14.5 0.0 0.13 12.9 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeat DUF3847 PF12958.7 EWM26440.1 - 0.11 12.7 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) Ank_4 PF13637.6 EWM26440.1 - 0.11 13.1 0.0 0.32 11.6 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Coprogen_oxidas PF01218.18 EWM26442.1 - 4.5e-105 350.6 0.0 5.6e-105 350.3 0.0 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Aa_trans PF01490.18 EWM26445.1 - 3e-27 95.4 12.1 1.3e-16 60.3 5.4 2.9 3 0 0 3 3 3 3 Transmembrane amino acid transporter protein DHO_dh PF01180.21 EWM26446.1 - 5.8e-99 331.0 0.0 6.9e-99 330.8 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase CENP-B_dimeris PF09026.10 EWM26447.1 - 0.076 13.4 0.3 0.17 12.3 0.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain MAGE_N PF12440.8 EWM26447.1 - 0.17 12.6 0.3 0.17 12.6 0.3 3.4 3 1 0 3 3 3 0 Melanoma associated antigen family N terminal Glyco_tranf_2_4 PF13704.6 EWM26448.1 - 1.4e-06 28.7 0.0 1.3e-05 25.6 0.0 2.4 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 EWM26448.1 - 3.7e-06 26.8 0.0 0.0014 18.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase family 92 Ribosomal_60s PF00428.19 EWM26450.1 - 2.4e-19 69.7 9.2 3.2e-19 69.3 9.2 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein eIF3_subunit PF08597.10 EWM26450.1 - 0.0056 16.6 0.9 0.0075 16.2 0.9 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Aminotran_1_2 PF00155.21 EWM26452.1 - 3.1e-38 131.9 0.0 6.8e-38 130.8 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 EWM26452.1 - 6.8e-05 21.9 0.0 0.0099 14.8 0.0 2.3 2 0 0 2 2 2 2 Allinase SPOR PF05036.13 EWM26452.1 - 0.081 13.3 0.0 6.9 7.1 0.0 2.5 2 0 0 2 2 2 0 Sporulation related domain Mito_carr PF00153.27 EWM26453.1 - 1.1e-52 175.9 0.6 2.2e-24 85.2 0.0 4.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EWM26453.1 - 0.02 14.0 0.1 0.52 9.4 0.1 2.4 2 0 0 2 2 2 0 Gammaproteobacterial serine protease Tim17 PF02466.19 EWM26453.1 - 0.071 13.5 3.3 0.4 11.1 0.7 3.1 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family TrbC PF04956.13 EWM26453.1 - 0.43 10.8 2.0 8.3 6.7 0.4 3.2 3 0 0 3 3 3 0 TrbC/VIRB2 family DUF3586 PF12131.8 EWM26454.1 - 0.041 14.1 0.1 0.077 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3586) Ribosomal_S8e PF01201.22 EWM26455.1 - 8.3e-49 165.3 2.6 1.7e-48 164.3 2.6 1.6 1 1 0 1 1 1 1 Ribosomal protein S8e Lipase_3 PF01764.25 EWM26457.1 - 5.5e-09 36.0 0.0 9.2e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) adh_short_C2 PF13561.6 EWM26458.1 - 3.1e-41 141.4 0.4 4e-41 141.1 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EWM26458.1 - 5.3e-32 110.9 0.1 6.9e-32 110.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EWM26458.1 - 7.8e-12 45.5 0.8 2e-11 44.1 0.7 1.7 1 1 1 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 EWM26458.1 - 2.4e-06 27.2 0.2 3.4e-06 26.7 0.2 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EWM26458.1 - 2.5e-06 27.1 0.1 3.5e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EWM26458.1 - 5.4e-06 26.4 0.4 2.6e-05 24.2 0.4 2.0 1 1 0 1 1 1 1 NAD(P)H-binding ApbA PF02558.16 EWM26458.1 - 0.00024 20.8 0.3 0.0032 17.1 0.2 2.2 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 EWM26458.1 - 0.00033 20.9 0.0 0.00064 20.0 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 EWM26458.1 - 0.00058 20.4 0.1 0.0052 17.3 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.13 EWM26458.1 - 0.0096 15.5 0.1 0.017 14.7 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 EWM26458.1 - 0.023 13.8 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EWM26458.1 - 0.039 13.0 0.0 0.058 12.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 EWM26458.1 - 0.058 13.7 0.0 0.17 12.1 0.0 1.9 1 1 0 1 1 1 0 TrkA-N domain RVT_2 PF07727.14 EWM26459.1 - 1.6e-67 227.6 0.0 2.8e-67 226.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 EWM26459.1 - 7.8e-11 42.2 0.0 2.7e-10 40.5 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 EWM26459.1 - 0.15 11.8 0.0 0.46 10.3 0.0 1.8 2 0 0 2 2 2 0 Integrase core domain zf-DNA_Pol PF08996.10 EWM26462.1 - 0.019 14.7 2.4 0.036 13.8 2.4 1.3 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger ODR4-like PF14778.6 EWM26463.1 - 0.041 12.8 0.0 0.044 12.7 0.0 1.0 1 0 0 1 1 1 0 Olfactory receptor 4-like Sortilin-Vps10 PF15902.5 EWM26464.1 - 7.4e-05 21.7 1.0 8.9e-05 21.4 1.0 1.1 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, PSII_BNR PF14870.6 EWM26464.1 - 0.017 14.4 2.8 0.022 14.0 2.8 1.1 1 0 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 GDPD_2 PF13653.6 EWM26464.1 - 0.68 10.5 3.4 1.8 9.1 0.3 2.3 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family BNR PF02012.20 EWM26464.1 - 1.8 8.9 16.6 0.7 10.1 0.8 3.5 4 0 0 4 4 4 0 BNR/Asp-box repeat BNR_3 PF13859.6 EWM26464.1 - 3.8 6.7 7.9 2.8 7.1 0.9 2.1 1 1 1 2 2 2 0 BNR repeat-like domain Neur_chan_memb PF02932.16 EWM26467.1 - 0.0039 17.3 4.5 0.57 10.2 2.1 2.2 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.14 EWM26467.1 - 0.018 13.4 0.8 0.025 12.9 0.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF5568 PF17724.1 EWM26467.1 - 0.58 9.9 3.6 1.1 9.1 3.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5568) DUF423 PF04241.15 EWM26468.1 - 2.7e-20 72.4 0.8 4e-20 71.8 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF423) DUF3792 PF12670.7 EWM26468.1 - 0.031 14.4 0.2 0.031 14.4 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) DUF202 PF02656.15 EWM26468.1 - 3.6 8.1 6.3 2.1 8.8 2.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Phage_int_SAM_5 PF13102.6 EWM26469.1 - 0.023 15.0 0.2 12 6.3 0.0 4.0 3 0 0 3 3 3 0 Phage integrase SAM-like domain DNA_pol_B_thumb PF14791.6 EWM26472.1 - 1.9e-18 66.4 0.0 5.3e-18 64.9 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 EWM26472.1 - 4.8e-09 36.4 5.6 5.9e-08 32.9 0.1 2.7 2 1 1 3 3 3 2 DNA polymerase beta palm HHH_8 PF14716.6 EWM26472.1 - 3.1e-05 24.3 0.0 8e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 EWM26472.1 - 0.00096 18.9 0.0 0.0022 17.8 0.0 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda Nramp PF01566.18 EWM26474.1 - 6.6e-120 400.3 21.7 1e-119 399.8 21.7 1.3 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein MG2 PF01835.19 EWM26475.1 - 0.14 12.6 0.0 0.32 11.5 0.0 1.5 1 0 0 1 1 1 0 MG2 domain Plasmodium_HRP PF05403.11 EWM26475.1 - 2.3 7.9 14.0 3.7 7.3 14.0 1.2 1 0 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) DUF3886 PF13025.6 EWM26475.1 - 3.7 7.8 6.6 7.2 6.9 6.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) Carb_kinase PF01256.17 EWM26476.1 - 1.3e-38 132.8 0.4 9.1e-37 126.8 0.4 2.8 1 1 0 1 1 1 1 Carbohydrate kinase DDHD PF02862.17 EWM26478.1 - 2.8e-39 135.6 2.2 3.8e-39 135.2 0.0 2.2 2 1 0 2 2 2 1 DDHD domain WWE PF02825.20 EWM26478.1 - 2.4e-06 28.0 0.2 0.0024 18.4 0.1 2.8 2 0 0 2 2 2 2 WWE domain DUF676 PF05057.14 EWM26478.1 - 0.00074 19.1 0.0 0.051 13.1 0.0 2.2 2 0 0 2 2 2 1 Putative serine esterase (DUF676) DUF3089 PF11288.8 EWM26478.1 - 0.031 13.8 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Hydrolase_4 PF12146.8 EWM26478.1 - 0.093 12.0 0.1 1 8.6 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 LCAT PF02450.15 EWM26478.1 - 0.2 10.8 0.0 1.2 8.2 0.0 2.1 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase Pkinase PF00069.25 EWM26479.1 - 8.5e-56 189.2 0.0 4.5e-50 170.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EWM26479.1 - 1.6e-32 112.8 0.0 8.1e-30 104.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EWM26479.1 - 0.03 13.1 0.0 0.055 12.2 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 EWM26479.1 - 0.043 13.1 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Fer2_4 PF13510.6 EWM26479.1 - 0.13 12.3 0.0 0.91 9.6 0.0 2.4 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain APH PF01636.23 EWM26479.1 - 0.18 11.7 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 EWM26480.1 - 5.7e-53 180.0 0.0 1.1e-46 159.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EWM26480.1 - 9.3e-32 110.3 0.0 3e-30 105.4 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EWM26480.1 - 0.0072 15.7 0.0 0.034 13.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EWM26480.1 - 0.026 13.3 0.0 0.06 12.1 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EWM26480.1 - 0.04 13.8 0.1 0.13 12.2 0.1 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF2764 PF10962.8 EWM26480.1 - 0.2 11.1 0.0 0.35 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2764) U3_assoc_6 PF08640.11 EWM26483.1 - 3.9e-24 84.5 1.6 5.6e-24 84.0 0.2 2.0 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 EWM26483.1 - 0.029 15.2 0.5 0.029 15.2 0.5 6.6 5 3 2 7 7 7 0 Tetratricopeptide repeat Suf PF05843.14 EWM26483.1 - 0.17 11.8 0.0 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Sortilin-Vps10 PF15902.5 EWM26484.1 - 0.003 16.4 3.0 0.0073 15.1 3.0 1.6 1 1 0 1 1 1 1 Sortilin, neurotensin receptor 3, BNR PF02012.20 EWM26484.1 - 0.0095 15.8 11.1 0.45 10.7 0.8 3.5 3 0 0 3 3 3 2 BNR/Asp-box repeat SfsA_N PF17746.1 EWM26484.1 - 0.012 15.8 0.0 0.024 14.8 0.0 1.5 1 0 0 1 1 1 0 SfsA N-terminal OB domain SfsA_N PF17746.1 EWM26485.1 - 0.0096 16.1 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 1 SfsA N-terminal OB domain BNR PF02012.20 EWM26485.1 - 0.35 11.1 3.1 0.37 11.0 0.8 2.5 2 0 0 2 2 2 0 BNR/Asp-box repeat AAA PF00004.29 EWM26487.1 - 1.8e-98 326.1 0.0 3.8e-48 163.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EWM26487.1 - 5.1e-26 90.2 7.8 4.4e-13 48.8 0.9 2.8 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 EWM26487.1 - 1.1e-19 70.4 1.5 1.8e-19 69.7 0.6 1.9 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.17 EWM26487.1 - 1.3e-14 53.7 0.1 3.5e-14 52.3 0.0 1.8 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), domain 2 RuvB_N PF05496.12 EWM26487.1 - 6.8e-14 51.9 0.0 8.6e-06 25.6 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EWM26487.1 - 2e-12 47.6 0.0 4.2e-06 27.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EWM26487.1 - 3e-12 47.3 0.9 0.00037 20.9 0.0 4.7 3 2 1 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 EWM26487.1 - 7.7e-11 42.2 0.0 1.4e-05 25.1 0.0 3.3 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EWM26487.1 - 1.4e-10 41.5 0.0 4.5e-05 23.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EWM26487.1 - 1.6e-10 41.4 0.4 0.014 15.6 0.0 5.0 4 2 0 4 4 3 2 AAA domain TIP49 PF06068.13 EWM26487.1 - 5.4e-08 32.4 0.0 0.00082 18.7 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 EWM26487.1 - 8.1e-08 32.4 0.0 0.0026 17.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 EWM26487.1 - 9.5e-07 28.7 0.2 1e-05 25.4 0.1 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_18 PF13238.6 EWM26487.1 - 1.3e-06 29.0 0.0 0.046 14.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EWM26487.1 - 1.4e-06 27.9 0.2 0.071 12.5 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EWM26487.1 - 1.5e-06 28.5 0.0 0.023 15.1 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.6 EWM26487.1 - 6.3e-06 25.9 1.1 1.9 8.0 0.0 4.1 3 2 1 5 5 4 1 AAA domain ATPase PF06745.13 EWM26487.1 - 8.6e-06 25.3 0.1 1.4 8.2 0.0 3.5 3 0 0 3 3 3 1 KaiC IstB_IS21 PF01695.17 EWM26487.1 - 9.8e-06 25.4 0.1 0.35 10.6 0.0 3.3 3 1 0 3 3 3 2 IstB-like ATP binding protein ATPase_2 PF01637.18 EWM26487.1 - 2.6e-05 24.2 0.0 0.16 11.8 0.0 3.0 2 1 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_7 PF12775.7 EWM26487.1 - 3e-05 23.6 0.0 0.16 11.5 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region Viral_helicase1 PF01443.18 EWM26487.1 - 3.4e-05 23.7 0.0 0.022 14.5 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 EWM26487.1 - 4.2e-05 24.0 0.9 0.12 12.8 0.0 2.9 3 0 0 3 3 2 2 AAA domain ABC_tran PF00005.27 EWM26487.1 - 5e-05 23.8 0.2 0.39 11.2 0.0 3.6 4 1 0 4 4 2 2 ABC transporter AAA_28 PF13521.6 EWM26487.1 - 8.3e-05 22.9 0.3 0.8 9.9 0.0 3.2 3 0 0 3 3 3 2 AAA domain Bac_DnaA PF00308.18 EWM26487.1 - 0.00018 21.4 0.0 0.16 11.8 0.0 2.6 2 0 0 2 2 2 1 Bacterial dnaA protein Sigma54_activat PF00158.26 EWM26487.1 - 0.00019 21.2 0.0 0.67 9.6 0.0 3.2 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.6 EWM26487.1 - 0.00021 21.1 0.0 0.21 11.3 0.0 2.8 3 0 0 3 3 2 1 AAA domain TsaE PF02367.17 EWM26487.1 - 0.00022 21.2 0.0 0.78 9.8 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE UFD1 PF03152.14 EWM26487.1 - 0.00025 20.6 0.0 0.00046 19.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Parvo_NS1 PF01057.17 EWM26487.1 - 0.00025 20.2 0.0 0.41 9.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NACHT PF05729.12 EWM26487.1 - 0.00035 20.5 0.0 3.1 7.7 0.0 3.6 3 1 1 4 4 4 1 NACHT domain NB-ARC PF00931.22 EWM26487.1 - 0.00044 19.5 0.0 1.1 8.4 0.0 2.8 3 0 0 3 3 3 2 NB-ARC domain Zeta_toxin PF06414.12 EWM26487.1 - 0.00058 19.2 0.0 0.77 9.0 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin Cytidylate_kin2 PF13189.6 EWM26487.1 - 0.0007 19.8 1.3 0.52 10.4 0.0 2.9 3 0 0 3 3 3 1 Cytidylate kinase-like family Sigma54_activ_2 PF14532.6 EWM26487.1 - 0.00099 19.2 0.0 0.52 10.4 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain ResIII PF04851.15 EWM26487.1 - 0.0011 19.0 0.0 0.13 12.3 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 EWM26487.1 - 0.0019 18.0 0.0 2.3 8.1 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 EWM26487.1 - 0.0019 17.4 0.0 0.44 9.7 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Rad17 PF03215.15 EWM26487.1 - 0.0028 17.6 0.0 0.71 9.8 0.0 2.8 3 0 0 3 3 2 1 Rad17 P-loop domain PhoH PF02562.16 EWM26487.1 - 0.005 16.3 0.1 4.4 6.7 0.0 2.7 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.6 EWM26487.1 - 0.0057 16.4 0.1 5.3 6.7 0.0 2.9 3 0 0 3 3 2 0 AAA domain DUF2075 PF09848.9 EWM26487.1 - 0.0068 15.7 0.0 1.1 8.5 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 EWM26487.1 - 0.0097 16.2 0.5 8.1 6.8 0.1 3.5 3 1 1 4 4 2 0 AAA domain AAA_11 PF13086.6 EWM26487.1 - 0.011 15.5 0.7 6.4 6.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 EWM26487.1 - 0.016 15.1 2.1 5 7.0 0.0 4.1 4 1 1 5 5 4 0 NTPase Molydop_binding PF01568.21 EWM26487.1 - 0.019 15.0 0.0 0.045 13.8 0.0 1.6 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain Cytidylate_kin PF02224.18 EWM26487.1 - 0.043 13.5 0.0 8.1 6.1 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase Zot PF05707.12 EWM26487.1 - 0.057 13.1 0.0 1.5 8.5 0.0 2.6 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) SKI PF01202.22 EWM26487.1 - 0.064 13.4 0.9 13 5.8 0.0 2.8 3 0 0 3 3 2 0 Shikimate kinase KAP_NTPase PF07693.14 EWM26487.1 - 0.077 12.2 0.1 3.2 6.9 0.0 3.0 2 2 1 4 4 4 0 KAP family P-loop domain DUF4637 PF15470.6 EWM26487.1 - 0.12 12.2 0.9 0.21 11.3 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) AAA_29 PF13555.6 EWM26487.1 - 0.12 12.1 0.0 8.1 6.3 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain Hydin_ADK PF17213.3 EWM26487.1 - 1.6 9.0 6.1 77 3.5 0.0 4.2 5 0 0 5 5 5 0 Hydin Adenylate kinase-like domain ANAPC8 PF04049.13 EWM26488.1 - 3.9e-25 88.5 0.0 1.1e-24 87.1 0.0 1.8 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 EWM26488.1 - 1.2e-24 85.1 24.6 8.8e-06 25.3 0.4 7.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 EWM26488.1 - 3.3e-21 73.7 10.9 4.8e-05 23.2 0.1 6.8 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 EWM26488.1 - 1.5e-18 65.3 36.4 0.00013 21.8 0.2 9.4 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 EWM26488.1 - 9.1e-14 51.7 22.3 4.6e-05 23.8 0.4 7.6 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 EWM26488.1 - 2.3e-13 49.6 8.2 7.7e-07 28.7 0.1 4.9 4 1 1 5 5 5 3 TPR repeat TPR_17 PF13431.6 EWM26488.1 - 4.9e-09 36.0 7.0 0.019 15.3 0.1 6.2 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 EWM26488.1 - 8e-09 35.6 36.2 0.00013 22.5 0.0 9.8 7 3 4 11 11 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EWM26488.1 - 1.7e-08 34.6 23.3 0.01 16.0 2.7 5.8 4 2 2 6 6 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EWM26488.1 - 6.6e-08 32.0 28.9 0.00085 19.2 0.1 7.8 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 EWM26488.1 - 2.5e-07 31.2 1.5 2.5e-07 31.2 1.5 9.4 5 2 5 10 10 10 2 Tetratricopeptide repeat TPR_12 PF13424.6 EWM26488.1 - 1.3e-05 25.4 36.5 0.00013 22.2 3.0 6.7 5 2 3 9 9 7 5 Tetratricopeptide repeat TPR_10 PF13374.6 EWM26488.1 - 0.0053 16.6 6.6 0.6 10.1 0.1 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EWM26488.1 - 0.0094 16.5 25.8 10 7.0 0.0 8.9 10 0 0 10 10 9 0 Tetratricopeptide repeat Herpes_pp85 PF04637.12 EWM26488.1 - 0.062 11.7 3.5 0.093 11.1 3.5 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) ChAPs PF09295.10 EWM26488.1 - 0.069 12.1 0.0 0.32 10.0 0.0 2.0 2 1 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_9 PF13371.6 EWM26488.1 - 0.082 13.1 28.4 0.13 12.4 2.4 5.3 5 1 1 6 6 4 0 Tetratricopeptide repeat Sel1 PF08238.12 EWM26488.1 - 0.76 10.6 8.0 17 6.2 0.4 4.4 4 0 0 4 4 3 0 Sel1 repeat Asp_protease PF09668.10 EWM26489.1 - 1.3e-18 66.9 0.7 2e-18 66.4 0.7 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EWM26489.1 - 2.9e-09 37.4 0.1 8.9e-09 35.8 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EWM26489.1 - 6.4e-06 26.7 0.0 1.8e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Cellulase PF00150.18 EWM26490.1 - 1.4e-40 139.5 1.1 1.8e-40 139.2 1.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) U-box PF04564.15 EWM26492.1 - 1.2e-06 28.6 0.0 1.3e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 EWM26492.1 - 0.00034 20.7 0.0 0.00043 20.4 0.0 1.2 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 EWM26492.1 - 0.0023 17.7 0.0 0.0027 17.5 0.0 1.2 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Rtf2 PF04641.12 EWM26492.1 - 0.062 12.6 0.0 0.067 12.5 0.0 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Amino_oxidase PF01593.24 EWM26493.1 - 2.8e-61 208.2 0.0 3.5e-61 207.9 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EWM26493.1 - 8.9e-10 38.7 0.0 2.2e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EWM26493.1 - 2.9e-05 23.8 0.0 5.6e-05 22.9 0.0 1.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EWM26493.1 - 2.9e-05 23.6 0.0 4.2e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EWM26493.1 - 0.00018 20.9 0.1 0.0003 20.1 0.1 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 EWM26493.1 - 0.0002 20.6 0.0 0.00032 19.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 EWM26493.1 - 0.00079 18.8 0.1 0.0011 18.2 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EWM26493.1 - 0.014 14.6 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EWM26493.1 - 0.11 11.6 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A MTS PF05175.14 EWM26494.1 - 6.9e-05 22.5 0.0 0.00077 19.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EWM26494.1 - 0.0035 17.2 0.0 0.0049 16.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 EWM26494.1 - 0.012 15.3 0.0 0.049 13.3 0.0 1.9 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 EWM26494.1 - 0.043 14.5 0.0 0.21 12.3 0.0 2.0 3 0 0 3 3 3 0 Methyltransferase domain Aa_trans PF01490.18 EWM26496.1 - 7.6e-13 47.9 7.4 9e-13 47.7 7.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ribosomal_L31e PF01198.19 EWM26499.1 - 7.7e-41 138.2 1.6 9.5e-41 137.9 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e MFS_1 PF07690.16 EWM26500.1 - 6.7e-06 25.3 0.3 8.7e-06 24.9 0.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 EWM26501.1 - 0.065 12.1 7.8 0.038 12.9 3.6 2.0 2 0 0 2 2 2 0 Major Facilitator Superfamily Pkinase_Tyr PF07714.17 EWM26502.1 - 6.4e-18 65.0 0.1 6.8e-18 64.9 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EWM26502.1 - 2.4e-15 56.6 0.0 2.8e-15 56.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pheromone PF08015.11 EWM26503.1 - 0.41 11.7 8.1 0.21 12.7 1.2 2.6 1 1 1 2 2 2 0 Fungal mating-type pheromone Tim54 PF11711.8 EWM26505.1 - 0.2 10.4 0.6 0.22 10.2 0.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 peroxidase PF00141.23 EWM26506.1 - 5.2e-05 23.1 0.0 6.5e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Peroxidase peroxidase PF00141.23 EWM26509.1 - 1.4e-13 51.1 0.0 1.9e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Peroxidase Glyco_hydro38C2 PF17677.1 EWM26511.1 - 0.00011 22.2 0.0 0.00019 21.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_38N PF01074.22 EWM26513.1 - 1.4e-06 27.9 0.5 1.6e-06 27.7 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Prp18 PF02840.15 EWM26514.1 - 9.1e-49 165.2 0.1 1e-48 165.0 0.1 1.0 1 0 0 1 1 1 1 Prp18 domain CaMBD PF02888.16 EWM26514.1 - 0.11 12.8 0.3 0.22 11.7 0.3 1.6 1 0 0 1 1 1 0 Calmodulin binding domain PRP4 PF08799.11 EWM26515.1 - 2.5e-09 36.5 0.2 2.5e-09 36.5 0.2 3.1 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like DUF3006 PF11213.8 EWM26515.1 - 2.8 8.2 6.9 0.5 10.6 2.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) Borealin PF10512.9 EWM26517.1 - 1.6e-11 44.2 1.0 4.5e-11 42.8 1.0 1.7 1 0 0 1 1 1 1 Cell division cycle-associated protein 8 Nbl1_Borealin_N PF10444.9 EWM26517.1 - 2.1e-11 43.3 2.4 4.2e-11 42.3 2.4 1.6 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Myb_DNA-binding PF00249.31 EWM26518.1 - 0.15 12.3 0.0 0.43 10.8 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain Cullin PF00888.22 EWM26520.1 - 9.1e-40 136.9 0.1 1.3e-39 136.4 0.1 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EWM26520.1 - 1.8e-24 85.5 0.4 4e-24 84.4 0.4 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain Cullin PF00888.22 EWM26521.1 - 8.4e-23 80.8 0.1 9e-23 80.7 0.1 1.0 1 0 0 1 1 1 1 Cullin family Cullin PF00888.22 EWM26522.1 - 2.2e-26 92.7 0.2 2.5e-26 92.5 0.2 1.0 1 0 0 1 1 1 1 Cullin family ING PF12998.7 EWM26523.1 - 3.1e-09 37.3 8.8 4.5e-07 30.4 2.1 2.4 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EWM26523.1 - 7e-07 29.0 7.0 1.5e-06 28.0 7.0 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EWM26523.1 - 0.081 12.5 2.4 0.23 11.0 2.4 1.8 1 0 0 1 1 1 0 PHD-finger NOA36 PF06524.12 EWM26523.1 - 0.23 10.8 36.2 0.35 10.2 14.8 2.5 2 0 0 2 2 2 0 NOA36 protein zf-HC5HC2H PF13771.6 EWM26523.1 - 2.4 8.5 8.8 1.8 8.9 5.0 2.5 2 1 0 2 2 2 0 PHD-like zinc-binding domain Peptidase_S64 PF08192.11 EWM26523.1 - 5.2 5.4 6.1 7.1 5.0 6.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 RPN2_C PF18004.1 EWM26523.1 - 6.8 6.6 29.9 6.6 6.6 9.4 2.4 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain SLC12 PF03522.15 EWM26523.1 - 9.6 5.1 6.2 15 4.5 6.2 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Allantoicase PF03561.15 EWM26524.1 - 1.9e-93 310.0 0.0 1.2e-47 161.5 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat HlyD_D4 PF16572.5 EWM26524.1 - 0.17 11.8 0.0 0.58 10.1 0.0 1.9 2 0 0 2 2 2 0 Long alpha hairpin domain of cation efflux system protein, CusB Allantoicase PF03561.15 EWM26525.1 - 1.9e-93 310.0 0.0 1.2e-47 161.5 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat HlyD_D4 PF16572.5 EWM26525.1 - 0.17 11.8 0.0 0.58 10.1 0.0 1.9 2 0 0 2 2 2 0 Long alpha hairpin domain of cation efflux system protein, CusB Endonuclease_5 PF04493.14 EWM26526.1 - 2.4e-57 193.8 0.0 1.6e-56 191.2 0.0 1.9 1 1 0 1 1 1 1 Endonuclease V DUF99 PF01949.16 EWM26526.1 - 0.016 14.6 0.0 0.089 12.2 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function DUF99 Pro_dh PF01619.18 EWM26527.1 - 2.2e-79 267.1 0.1 1.7e-78 264.2 0.1 1.9 1 1 0 1 1 1 1 Proline dehydrogenase EF-hand_7 PF13499.6 EWM26527.1 - 3.2e-05 24.3 0.1 0.0077 16.7 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 EWM26527.1 - 0.00036 20.3 0.3 0.002 17.9 0.0 2.4 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 EWM26527.1 - 0.00076 19.2 1.1 0.0072 16.2 0.4 2.5 2 0 0 2 2 2 1 EF-hand domain DUF1917 PF08939.10 EWM26527.1 - 0.0065 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) EF-hand_1 PF00036.32 EWM26527.1 - 0.035 13.6 1.0 0.66 9.7 0.5 2.5 2 0 0 2 2 2 0 EF hand eIF-5_eIF-2B PF01873.17 EWM26528.1 - 2.1e-35 121.1 0.0 3.3e-35 120.5 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Cullin PF00888.22 EWM26529.1 - 2.9e-15 55.9 1.2 3.3e-15 55.7 1.2 1.0 1 0 0 1 1 1 1 Cullin family Tn7_Tnp_TnsA_N PF08722.11 EWM26529.1 - 0.048 13.9 0.2 0.094 12.9 0.2 1.5 1 1 0 1 1 1 0 TnsA endonuclease N terminal GST_N_3 PF13417.6 EWM26530.1 - 9.8e-28 96.4 0.0 8.1e-14 51.8 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EWM26530.1 - 1.6e-10 41.1 0.0 4.5e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 EWM26530.1 - 1e-05 25.6 0.1 0.0031 17.7 0.1 2.4 2 0 0 2 2 2 2 Glutaredoxin GST_N PF02798.20 EWM26530.1 - 3.7e-05 24.0 0.0 0.22 11.9 0.0 2.3 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EWM26531.1 - 8.4e-17 61.4 0.0 1.7e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EWM26531.1 - 8.7e-13 48.4 0.1 1.7e-12 47.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EWM26531.1 - 1.2e-11 44.7 0.0 2.3e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 EWM26531.1 - 1.1e-07 32.4 0.0 2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EWM26531.1 - 3.2e-06 27.1 0.0 7.9e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EWM26531.1 - 0.0011 19.1 0.0 0.0048 17.1 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 EWM26531.1 - 0.027 14.7 0.0 0.062 13.5 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin UCMA PF17085.5 EWM26532.1 - 0.03 14.3 1.0 0.056 13.5 1.0 1.4 1 0 0 1 1 1 0 Unique cartilage matrix associated protein PAP_central PF04928.17 EWM26533.1 - 1.5e-61 207.5 0.2 3.6e-61 206.3 0.0 1.6 2 0 0 2 2 2 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 EWM26533.1 - 7.3e-13 48.5 0.6 1.2e-08 34.8 0.0 3.4 3 1 1 4 4 4 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 EWM26533.1 - 6.5e-07 29.6 0.0 1.6e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Ank_2 PF12796.7 EWM26533.1 - 0.014 16.0 0.0 0.049 14.2 0.0 1.8 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EWM26533.1 - 0.031 14.6 0.0 0.13 12.6 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeats (many copies) DUF4269 PF14091.6 EWM26533.1 - 0.044 14.0 0.0 0.076 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) Ank PF00023.30 EWM26533.1 - 0.067 13.7 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat Ank_4 PF13637.6 EWM26533.1 - 0.13 12.9 0.0 0.56 10.9 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeats (many copies) RNA_pol_Rpc4 PF05132.14 EWM26533.1 - 0.81 10.1 5.0 15 6.0 0.2 2.7 2 1 0 2 2 2 0 RNA polymerase III RPC4 WzyE PF06899.11 EWM26535.1 - 0.079 11.9 0.1 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 WzyE protein, O-antigen assembly polymerase RNA_pol_N PF01194.17 EWM26536.1 - 8.8e-30 102.8 1.0 1.5e-29 102.1 1.0 1.4 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 EWM26536.1 - 0.59 10.4 4.4 0.21 11.9 1.3 1.9 2 1 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) PPR_2 PF13041.6 EWM26537.1 - 2.6e-24 85.2 0.0 6.6e-07 29.4 0.0 5.4 5 0 0 5 5 5 4 PPR repeat family PPR PF01535.20 EWM26537.1 - 1e-19 69.3 2.8 0.0091 16.2 0.0 7.1 8 0 0 8 8 8 5 PPR repeat PPR_3 PF13812.6 EWM26537.1 - 2.9e-15 56.1 0.0 0.00086 19.3 0.0 5.3 3 2 0 5 5 5 4 Pentatricopeptide repeat domain PPR_1 PF12854.7 EWM26537.1 - 4.9e-08 32.5 0.0 0.18 11.5 0.0 6.0 6 0 0 6 6 6 2 PPR repeat PPR_long PF17177.4 EWM26537.1 - 2.5e-05 23.7 0.0 0.16 11.3 0.0 2.7 1 1 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 EWM26537.1 - 0.068 13.7 0.2 2.1 8.9 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Mem_trans PF03547.18 EWM26539.1 - 4.8e-22 77.9 14.8 1.7e-13 49.8 0.1 2.1 1 1 1 2 2 2 2 Membrane transport protein SBF PF01758.16 EWM26539.1 - 0.072 12.8 7.9 0.16 11.6 7.9 1.5 1 0 0 1 1 1 0 Sodium Bile acid symporter family Mem_trans PF03547.18 EWM26540.1 - 3.7e-22 78.3 14.8 1.5e-13 49.9 0.1 2.1 1 1 1 2 2 2 2 Membrane transport protein SBF PF01758.16 EWM26540.1 - 0.068 12.8 7.9 0.15 11.8 7.9 1.5 1 0 0 1 1 1 0 Sodium Bile acid symporter family Phage_holin_Dp1 PF16938.5 EWM26540.1 - 0.22 11.8 1.2 8.9 6.6 0.1 3.1 2 0 0 2 2 2 0 Putative phage holin Dp-1 AAA PF00004.29 EWM26544.1 - 1.4e-41 142.0 0.0 2.5e-41 141.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EWM26544.1 - 8.8e-14 51.1 0.0 1.6e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EWM26544.1 - 4.7e-07 30.4 2.2 0.00086 19.7 0.1 2.9 2 1 1 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 EWM26544.1 - 1.6e-05 25.2 0.2 0.022 15.0 0.0 2.8 2 1 1 3 3 3 2 AAA domain TIP49 PF06068.13 EWM26544.1 - 3.5e-05 23.2 0.0 6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 EWM26544.1 - 8.5e-05 22.6 0.0 0.0003 20.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EWM26544.1 - 0.00022 21.4 0.0 0.00051 20.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 EWM26544.1 - 0.00028 21.3 0.0 0.00061 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EWM26544.1 - 0.00045 20.8 0.0 0.00098 19.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EWM26544.1 - 0.00048 19.9 0.0 0.0012 18.6 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EWM26544.1 - 0.00097 19.4 0.0 0.0017 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EWM26544.1 - 0.0015 18.3 0.0 0.0027 17.5 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 EWM26544.1 - 0.005 17.0 0.0 0.012 15.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EWM26544.1 - 0.0087 15.5 0.2 0.023 14.1 0.2 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EWM26544.1 - 0.014 15.4 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 EWM26544.1 - 0.023 14.5 0.1 0.052 13.3 0.0 1.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EWM26544.1 - 0.04 13.8 0.1 0.13 12.1 0.1 1.9 1 1 1 2 2 2 0 NACHT domain AAA_25 PF13481.6 EWM26544.1 - 0.064 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EWM26544.1 - 0.068 12.4 0.3 0.13 11.5 0.3 1.3 1 0 0 1 1 1 0 Zeta toxin FtsH_ext PF06480.15 EWM26544.1 - 0.098 13.0 0.0 0.3 11.5 0.0 1.8 1 1 0 1 1 1 0 FtsH Extracellular Sigma54_activat PF00158.26 EWM26544.1 - 0.11 12.2 0.0 0.51 10.0 0.0 1.9 1 1 1 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 EWM26544.1 - 0.15 11.8 0.0 0.6 9.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 EWM26544.1 - 0.16 12.1 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 EWM26544.1 - 0.17 11.9 0.0 0.71 9.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EWM26544.1 - 0.17 11.0 0.0 0.61 9.2 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF815) Pkinase PF00069.25 EWM26545.1 - 7.8e-51 173.0 0.0 9.3e-51 172.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM26545.1 - 4.4e-21 75.3 0.0 5.8e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EWM26545.1 - 2e-05 24.0 0.0 2.8e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EWM26545.1 - 0.0038 16.1 0.0 0.0054 15.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EWM26545.1 - 0.0086 16.0 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 EWM26545.1 - 0.19 11.2 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL LpqV PF17301.2 EWM26546.1 - 0.0086 16.3 0.1 0.016 15.4 0.1 1.5 1 0 0 1 1 1 1 Putative lipoprotein LpqV Proteasome PF00227.26 EWM26547.1 - 1.3e-58 197.7 0.0 1.5e-58 197.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EWM26547.1 - 6.9e-09 35.2 1.5 1.2e-08 34.5 0.1 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Myb_DNA-binding PF00249.31 EWM26549.1 - 3.5e-36 123.2 8.1 3e-12 46.5 0.1 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EWM26549.1 - 8.2e-13 48.4 7.9 0.00054 20.1 0.1 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EWM26549.1 - 9.2e-11 41.5 9.9 0.00065 19.5 0.6 3.3 3 0 0 3 3 3 3 Myb DNA-binding like RRM_1 PF00076.22 EWM26550.1 - 2.6e-05 23.9 0.0 0.0029 17.4 0.0 2.7 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SMC_N PF02463.19 EWM26551.1 - 2.7e-26 92.4 0.0 5.8e-12 45.5 0.0 2.8 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EWM26551.1 - 2e-10 41.5 31.6 2e-10 41.5 31.6 5.6 3 2 1 4 4 3 1 AAA domain AAA_15 PF13175.6 EWM26551.1 - 5.1e-07 29.7 14.4 5.1e-07 29.7 14.4 3.4 2 2 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 EWM26551.1 - 2.1e-05 24.5 2.2 0.0086 15.9 0.0 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EWM26551.1 - 0.0012 18.5 0.0 0.0037 17.0 0.0 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 EWM26551.1 - 0.0025 18.0 0.0 0.0089 16.2 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit YojJ PF10372.9 EWM26551.1 - 0.011 15.8 0.5 0.95 9.6 0.0 3.4 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus AAA_16 PF13191.6 EWM26551.1 - 1.1 9.6 0.0 1.1 9.6 0.0 4.0 5 1 0 5 5 4 0 AAA ATPase domain ABC_tran PF00005.27 EWM26551.1 - 1.1 9.7 0.0 1.1 9.7 0.0 5.0 4 1 1 5 5 5 0 ABC transporter NPV_P10 PF05531.12 EWM26551.1 - 3.4 8.2 21.7 0.2 12.1 2.1 5.8 4 1 2 6 6 6 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 EWM26551.1 - 8.7 6.4 7.8 0.67 10.0 0.6 2.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA PF00004.29 EWM26552.1 - 9.8e-35 119.9 0.0 2.5e-34 118.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EWM26552.1 - 1.1e-08 34.8 0.1 2.5e-08 33.6 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_33 PF13671.6 EWM26552.1 - 1.3e-05 25.3 0.5 6.1e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF2722 PF10846.8 EWM26552.1 - 3.1e-05 23.1 2.6 4.9e-05 22.5 2.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Hydin_ADK PF17213.3 EWM26552.1 - 9.3e-05 22.8 4.7 0.087 13.1 0.0 3.5 3 0 0 3 3 3 2 Hydin Adenylate kinase-like domain RuvB_N PF05496.12 EWM26552.1 - 0.00017 21.4 0.0 0.00043 20.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EWM26552.1 - 0.00034 20.6 0.7 0.0043 17.0 0.7 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EWM26552.1 - 0.00067 19.1 0.1 0.0019 17.6 0.1 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Spt20 PF12090.8 EWM26552.1 - 0.00074 19.2 9.8 0.0011 18.6 9.8 1.3 1 0 0 1 1 1 1 Spt20 family AAA_16 PF13191.6 EWM26552.1 - 0.00078 19.9 7.7 0.019 15.4 0.1 4.0 4 1 1 5 5 4 1 AAA ATPase domain IstB_IS21 PF01695.17 EWM26552.1 - 0.0022 17.7 2.2 0.005 16.6 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 EWM26552.1 - 0.0023 18.1 0.0 0.0023 18.1 0.0 2.0 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 EWM26552.1 - 0.02 14.1 0.1 0.035 13.3 0.1 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_22 PF13401.6 EWM26552.1 - 0.024 14.9 0.1 0.024 14.9 0.1 3.6 2 1 2 4 4 3 0 AAA domain Vps4_C PF09336.10 EWM26552.1 - 0.042 13.9 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain PhoH PF02562.16 EWM26552.1 - 0.057 12.9 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.6 EWM26552.1 - 0.068 13.7 0.0 0.068 13.7 0.0 2.2 2 1 1 3 3 1 0 AAA domain AAA_24 PF13479.6 EWM26552.1 - 0.079 12.7 7.4 0.11 12.2 0.1 3.4 4 0 0 4 4 4 0 AAA domain AAA_11 PF13086.6 EWM26552.1 - 0.079 12.7 3.7 3.7 7.3 0.6 2.7 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EWM26552.1 - 0.093 13.1 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TFIIA PF03153.13 EWM26552.1 - 0.1 12.6 20.3 0.15 12.0 20.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Bac_DnaA PF00308.18 EWM26552.1 - 0.11 12.4 0.2 9.2 6.0 0.1 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_28 PF13521.6 EWM26552.1 - 0.11 12.7 0.1 0.11 12.7 0.1 3.3 4 1 0 4 4 2 0 AAA domain Ndc1_Nup PF09531.10 EWM26552.1 - 1.5 7.4 4.4 1.9 7.1 4.4 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SARAF PF06682.12 EWM26552.1 - 1.7 8.2 8.3 4.4 6.9 8.4 1.6 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Suf PF05843.14 EWM26552.1 - 3.4 7.6 11.1 6.5 6.7 11.1 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TSP9 PF11493.8 EWM26552.1 - 3.7 8.3 6.0 16 6.2 0.0 2.6 2 0 0 2 2 2 0 Thylakoid soluble phosphoprotein TSP9 CNDH2_N PF06278.11 EWM26552.1 - 4.7 7.5 8.0 19 5.5 6.9 2.2 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal S-AdoMet_synt_C PF02773.16 EWM26553.1 - 2.2e-66 222.1 0.1 2e-65 219.0 0.0 2.0 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 EWM26553.1 - 5.7e-47 158.9 0.0 1.1e-46 157.9 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 EWM26553.1 - 3.1e-42 143.3 0.4 6.1e-42 142.3 0.4 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain HSP70 PF00012.20 EWM26556.1 - 8.7e-250 830.0 10.1 1.1e-249 829.7 10.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EWM26556.1 - 7.8e-17 61.1 0.2 1.8e-15 56.6 0.3 2.3 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.18 EWM26556.1 - 0.021 14.1 0.1 0.11 11.7 0.1 2.2 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase FGGY_C PF02782.16 EWM26556.1 - 0.022 14.5 0.0 0.21 11.3 0.0 2.4 3 0 0 3 3 3 0 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 EWM26556.1 - 0.044 14.2 1.7 3 8.3 0.0 3.4 3 2 0 3 3 3 0 Cell division protein FtsA Rhodanese PF00581.20 EWM26557.1 - 1.7e-24 86.4 0.0 6.9e-15 55.5 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain cNMP_binding PF00027.29 EWM26558.1 - 1.4e-08 34.7 0.0 5.8e-05 23.1 0.0 2.9 2 1 1 3 3 3 2 Cyclic nucleotide-binding domain Sulfate_transp PF00916.20 EWM26558.1 - 2.9e-05 23.0 0.8 5.4e-05 22.1 0.0 1.8 2 0 0 2 2 2 1 Sulfate permease family STAS PF01740.21 EWM26558.1 - 0.00012 21.7 0.1 0.0015 18.1 0.0 2.5 2 1 0 2 2 2 1 STAS domain TctB PF07331.11 EWM26558.1 - 0.0016 18.7 1.6 0.0029 17.9 1.6 1.3 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctB family Oxidored_FMN PF00724.20 EWM26559.1 - 3.1e-80 270.0 0.0 4e-80 269.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 EWM26559.1 - 1.1e-24 87.1 2.4 1.3e-24 86.9 0.6 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EWM26559.1 - 1.3e-10 41.3 1.9 1.8e-10 40.9 0.0 2.3 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EWM26559.1 - 9e-10 39.0 1.2 5.5e-05 23.6 0.2 4.1 4 1 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EWM26559.1 - 1.8e-09 37.6 2.3 1.6e-06 28.0 0.1 4.1 4 0 0 4 4 4 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EWM26559.1 - 1.3e-08 34.5 0.6 0.0012 18.1 0.3 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EWM26559.1 - 4e-08 32.4 0.9 4e-08 32.4 0.9 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 EWM26559.1 - 1.1e-07 31.6 0.0 1.6e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EWM26559.1 - 1.3e-07 31.1 2.4 2.4e-07 30.2 1.5 1.8 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 EWM26559.1 - 2.4e-05 23.6 0.4 6.2e-05 22.2 0.2 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 EWM26559.1 - 0.00028 20.2 0.3 0.0058 15.9 0.1 2.3 2 0 0 2 2 2 1 Thi4 family FMO-like PF00743.19 EWM26559.1 - 0.00032 19.2 0.0 0.0025 16.3 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like 3HCDH_N PF02737.18 EWM26559.1 - 0.00049 20.0 0.1 0.019 14.9 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 EWM26559.1 - 0.0017 17.7 0.7 0.0087 15.3 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 EWM26559.1 - 0.0044 16.4 0.1 0.018 14.3 0.1 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 EWM26559.1 - 0.0056 16.7 3.2 0.2 11.7 0.1 3.6 4 0 0 4 4 3 1 FAD-NAD(P)-binding PEP_mutase PF13714.6 EWM26559.1 - 0.0057 16.1 0.1 0.34 10.3 0.1 2.3 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase AlaDh_PNT_C PF01262.21 EWM26559.1 - 0.018 14.4 1.2 0.025 13.9 0.1 1.8 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EWM26559.1 - 0.021 14.2 0.8 1.1 8.6 0.1 2.8 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EWM26559.1 - 0.022 14.7 0.1 0.19 11.7 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.14 EWM26559.1 - 0.04 13.5 1.0 0.076 12.6 0.0 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain K_oxygenase PF13434.6 EWM26559.1 - 0.069 12.3 0.1 9.2 5.3 0.0 2.9 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.18 EWM26559.1 - 0.12 12.6 0.0 50 4.2 0.0 3.2 2 1 0 3 3 3 0 TrkA-N domain F420_oxidored PF03807.17 EWM26559.1 - 0.15 12.7 0.2 20 5.8 0.0 2.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Lycopene_cycl PF05834.12 EWM26559.1 - 0.18 10.8 1.9 0.17 10.9 0.3 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein ThiF PF00899.21 EWM26559.1 - 0.57 9.5 2.2 1.2 8.4 0.1 2.2 2 0 0 2 2 2 0 ThiF family Peptidase_M24 PF00557.24 EWM26560.1 - 5.3e-52 176.6 0.0 6.4e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Glyco_transf_92 PF01697.27 EWM26561.1 - 2.2e-13 50.5 0.3 4.3e-13 49.5 0.3 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 EWM26561.1 - 2.1e-12 47.4 0.0 4.7e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glycos_transf_2 PF00535.26 EWM26561.1 - 0.00079 19.3 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Peptidase_M41 PF01434.18 EWM26562.1 - 0.072 12.9 0.0 5.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Peptidase family M41 Peptidase_M50 PF02163.22 EWM26562.1 - 0.093 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M50 PI3_PI4_kinase PF00454.27 EWM26563.1 - 2.9e-45 155.1 0.0 5.9e-45 154.0 0.0 1.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase WBS_methylT PF12589.8 EWM26564.1 - 1.7e-17 64.0 11.0 2.6e-17 63.4 11.0 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 EWM26564.1 - 0.013 16.1 0.0 0.029 15.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain RRM_1 PF00076.22 EWM26565.1 - 3.4e-24 84.4 0.0 6.1e-24 83.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EWM26565.1 - 0.0013 18.7 0.0 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 RNA binding motif LRR_8 PF13855.6 EWM26566.1 - 2.5e-13 49.6 3.3 1.6e-07 31.0 0.2 3.4 1 1 3 4 4 4 4 Leucine rich repeat Pkinase_Tyr PF07714.17 EWM26566.1 - 5.5e-13 48.8 0.0 3.8e-11 42.8 0.0 2.8 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EWM26566.1 - 6.6e-12 45.4 0.0 3.2e-10 39.8 0.0 2.9 3 0 0 3 3 3 1 Protein kinase domain LRR_4 PF12799.7 EWM26566.1 - 1.4e-08 34.9 3.2 0.0016 18.8 1.1 3.8 1 1 3 5 5 5 4 Leucine Rich repeats (2 copies) Kdo PF06293.14 EWM26566.1 - 0.00011 21.6 0.2 0.00027 20.4 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EWM26566.1 - 0.048 13.6 0.2 0.2 11.5 0.1 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EWM26566.1 - 0.21 10.9 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like LRR_1 PF00560.33 EWM26566.1 - 0.87 10.4 2.4 48 5.1 0.2 3.8 3 0 0 3 3 3 0 Leucine Rich Repeat MCM PF00493.23 EWM26571.1 - 5.8e-77 257.8 0.0 8.6e-77 257.2 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EWM26571.1 - 1.5e-26 92.7 0.1 6e-26 90.8 0.0 1.9 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 EWM26571.1 - 1.4e-21 76.7 2.8 2.5e-16 59.9 0.4 2.5 2 0 0 2 2 2 2 MCM AAA-lid domain Mg_chelatase PF01078.21 EWM26571.1 - 6.7e-09 35.4 0.0 1.5e-06 27.8 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EWM26571.1 - 3.8e-07 30.2 0.0 1.2e-06 28.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EWM26571.1 - 8.7e-06 25.6 0.0 2.2e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EWM26571.1 - 1e-05 25.3 0.0 8.8e-05 22.3 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 EWM26571.1 - 0.00031 21.2 0.3 0.0017 18.8 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EWM26571.1 - 0.0031 17.3 0.0 0.011 15.5 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 EWM26571.1 - 0.018 15.5 0.1 0.077 13.4 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EWM26571.1 - 0.094 13.0 0.0 1.2 9.4 0.0 2.7 2 1 0 3 3 3 0 AAA domain DUF815 PF05673.13 EWM26571.1 - 0.14 11.3 0.0 0.35 10.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Asp PF00026.23 EWM26574.1 - 1.4e-58 198.8 0.0 9.5e-46 156.6 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EWM26574.1 - 9.1e-11 42.3 0.1 1e-05 25.8 0.0 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp PF00026.23 EWM26575.1 - 1.6e-58 198.6 0.0 1.2e-45 156.4 0.0 2.9 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EWM26575.1 - 1.2e-10 41.9 0.1 2.8e-07 30.9 0.1 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Hydantoinase_B PF02538.14 EWM26576.1 - 1.2e-136 456.2 0.0 1.5e-136 455.8 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EWM26576.1 - 1.6e-88 296.8 0.3 2.8e-88 295.9 0.3 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EWM26576.1 - 3.2e-47 160.5 0.6 2.6e-46 157.6 0.1 2.2 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 EWM26576.1 - 0.0023 16.6 0.3 0.76 8.3 0.0 2.2 2 0 0 2 2 2 2 MutL protein Mito_carr PF00153.27 EWM26577.1 - 3.4e-52 174.3 6.5 5.7e-19 67.8 0.2 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein HTH_51 PF18558.1 EWM26577.1 - 0.042 13.7 0.0 1.9 8.4 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain Tim17 PF02466.19 EWM26577.1 - 0.28 11.6 3.0 0.7 10.3 1.3 2.5 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family EF-hand_1 PF00036.32 EWM26578.1 - 2.2e-27 92.5 8.7 5.6e-08 31.8 1.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EWM26578.1 - 1.4e-26 92.7 5.0 5.4e-13 49.2 1.6 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EWM26578.1 - 3e-23 81.4 6.4 2.8e-13 49.5 1.1 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EWM26578.1 - 9.3e-23 78.2 5.4 2.6e-07 30.1 0.0 4.3 4 1 0 4 4 4 4 EF-hand domain EF-hand_9 PF14658.6 EWM26578.1 - 3.3e-12 46.5 0.1 3.2e-05 24.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EWM26578.1 - 8.1e-10 37.8 12.3 0.0078 15.7 1.4 4.9 4 1 1 5 5 5 3 EF hand CCD48 PF15799.5 EWM26578.1 - 0.00026 19.5 0.1 0.0009 17.7 0.1 1.7 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 48 EF-hand_4 PF12763.7 EWM26578.1 - 0.0011 18.9 1.5 4.4 7.3 0.0 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 EWM26578.1 - 0.0012 19.0 0.0 0.012 15.8 0.0 2.3 3 0 0 3 3 3 1 Dockerin type I domain EF-hand_11 PF08976.11 EWM26578.1 - 0.036 14.9 0.1 5 8.0 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain DUF3008 PF11450.8 EWM26578.1 - 0.037 14.2 0.3 0.13 12.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknwon function (DUF3008) DUF5486 PF17588.2 EWM26578.1 - 0.85 9.5 0.1 0.85 9.5 0.1 3.4 4 0 0 4 4 4 0 Family of unknown function (DUF5486) TRAPPC-Trs85 PF12739.7 EWM26579.1 - 1.4e-63 215.3 0.0 2.2e-63 214.7 0.0 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit SNAP PF14938.6 EWM26579.1 - 0.027 13.9 0.1 3.2 7.1 0.0 2.2 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP PKD PF00801.20 EWM26579.1 - 0.038 13.8 0.0 0.13 12.1 0.0 1.9 1 0 0 1 1 1 0 PKD domain TPR_2 PF07719.17 EWM26579.1 - 0.14 12.3 0.1 45 4.5 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Inhibitor_I53 PF11714.8 EWM26579.1 - 0.87 9.8 3.1 24 5.2 0.6 2.5 2 0 0 2 2 2 0 Thrombin inhibitor Madanin Mito_carr PF00153.27 EWM26580.1 - 2.1e-30 104.5 7.6 5.1e-13 48.7 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Apolipoprotein PF01442.18 EWM26581.1 - 0.029 14.2 4.4 0.042 13.7 4.4 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 EWM26581.1 - 0.22 12.1 6.3 0.13 12.9 3.9 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) VDE PF07137.11 EWM26585.1 - 5.1e-35 121.1 0.0 6.9e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 VDE lipocalin domain DUF3446 PF11928.8 EWM26585.1 - 0.64 10.3 9.4 5.9 7.3 2.3 3.0 3 0 0 3 3 3 0 Early growth response N-terminal domain PhoLip_ATPase_C PF16212.5 EWM26586.1 - 1.2e-67 228.4 19.6 3.1e-67 227.0 19.6 1.8 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EWM26586.1 - 5.8e-18 64.3 0.0 1.4e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EWM26586.1 - 8.5e-13 49.1 0.2 4.4e-05 23.9 0.0 3.4 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EWM26586.1 - 2.5e-09 37.1 0.0 1.6e-08 34.5 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EWM26586.1 - 1.4e-07 31.2 2.1 1.4e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EWM26586.1 - 0.00059 19.6 0.0 0.0032 17.3 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase TPT PF03151.16 EWM26587.1 - 1.7e-12 47.3 11.2 2.1e-12 47.0 11.2 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EWM26587.1 - 4.5e-10 39.8 23.7 2.5e-09 37.4 3.5 2.5 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EWM26587.1 - 2.7e-06 26.8 15.3 8.1e-06 25.2 15.3 1.8 1 1 0 1 1 1 1 UAA transporter family PCI PF01399.27 EWM26588.1 - 1.1e-14 54.8 0.5 5.3e-14 52.6 0.1 2.1 2 0 0 2 2 2 1 PCI domain CorA PF01544.18 EWM26589.1 - 1.2e-44 152.8 0.3 2.9e-39 135.1 0.1 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein EF-hand_5 PF13202.6 EWM26589.1 - 0.011 15.2 0.7 0.032 13.7 0.0 2.2 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 EWM26589.1 - 0.019 14.8 0.1 0.06 13.3 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain KxDL PF10241.9 EWM26589.1 - 0.038 14.3 0.4 0.11 12.8 0.4 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein EF-hand_8 PF13833.6 EWM26589.1 - 0.04 13.8 0.3 4.7 7.1 0.0 3.3 3 0 0 3 3 3 0 EF-hand domain pair HisKA_2 PF07568.12 EWM26589.1 - 0.1 12.7 0.2 0.27 11.4 0.2 1.7 1 0 0 1 1 1 0 Histidine kinase Rx_N PF18052.1 EWM26589.1 - 0.19 12.0 0.6 0.43 10.9 0.6 1.5 1 0 0 1 1 1 0 Rx N-terminal domain HEAT_2 PF13646.6 EWM26590.1 - 4.6e-15 55.8 11.5 7.2e-09 35.9 3.0 3.3 3 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 EWM26590.1 - 7.7e-09 35.9 5.4 2.6e-08 34.2 1.7 4.8 4 1 1 5 5 5 2 HEAT-like repeat HEAT PF02985.22 EWM26590.1 - 2.2e-08 33.6 10.3 3.3e-05 23.8 0.1 4.7 5 1 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 EWM26590.1 - 5.5e-05 23.3 0.0 0.00011 22.3 0.0 1.5 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 EWM26590.1 - 0.0013 18.7 1.0 0.022 14.8 0.1 3.2 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 EWM26590.1 - 0.0022 18.5 18.4 0.032 14.9 0.4 5.3 5 1 0 5 5 5 2 PBS lyase HEAT-like repeat Adaptin_N PF01602.20 EWM26590.1 - 0.0088 14.6 0.0 0.016 13.8 0.0 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Cohesin_HEAT PF12765.7 EWM26590.1 - 0.18 12.1 6.0 5.9 7.3 0.2 3.3 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion ABC1 PF03109.16 EWM26591.1 - 6.8e-28 97.2 0.0 1.3e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 EWM26591.1 - 3.3e-05 23.6 0.0 0.00046 19.8 0.0 2.4 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 EWM26591.1 - 5.6e-05 23.2 1.9 0.00012 22.1 0.1 2.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 EWM26591.1 - 0.0014 18.1 0.0 0.012 14.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain TPX2 PF06886.11 EWM26591.1 - 0.11 12.7 3.5 0.26 11.5 3.5 1.6 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) Ras PF00071.22 EWM26593.1 - 2e-67 225.8 0.6 2.4e-67 225.6 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EWM26593.1 - 3.7e-37 127.2 0.8 5.8e-37 126.6 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EWM26593.1 - 4e-18 65.5 0.1 4.8e-18 65.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EWM26593.1 - 6.4e-06 26.2 0.1 2.4e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EWM26593.1 - 6.6e-06 26.1 0.7 0.09 12.7 0.2 2.3 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EWM26593.1 - 7.2e-06 25.5 0.0 8.3e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EWM26593.1 - 1.2e-05 24.9 0.1 1.5e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EWM26593.1 - 8.6e-05 22.2 0.1 0.00018 21.1 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA PF00004.29 EWM26593.1 - 0.0078 16.6 0.3 0.46 10.9 0.0 2.2 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EWM26593.1 - 0.019 15.3 0.0 0.03 14.7 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 EWM26593.1 - 0.031 14.0 0.1 0.99 9.1 0.0 2.3 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 EWM26593.1 - 0.031 14.3 0.1 0.058 13.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EWM26593.1 - 0.032 14.5 0.1 0.063 13.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EWM26593.1 - 0.039 14.5 0.1 0.077 13.5 0.1 1.5 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.18 EWM26593.1 - 0.046 13.3 0.0 0.21 11.1 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_7 PF12775.7 EWM26593.1 - 0.05 13.1 0.1 0.16 11.5 0.0 1.8 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_29 PF13555.6 EWM26593.1 - 0.057 13.2 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain LANC_like PF05147.13 EWM26593.1 - 0.073 11.6 0.1 0.19 10.3 0.0 1.6 1 1 0 1 1 1 0 Lanthionine synthetase C-like protein Septin PF00735.18 EWM26593.1 - 0.074 12.3 0.0 0.16 11.2 0.0 1.5 1 1 0 1 1 1 0 Septin Dioxygenase_N PF04444.14 EWM26593.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Catechol dioxygenase N terminus TniB PF05621.11 EWM26593.1 - 0.15 11.5 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein DUF1011 PF06237.12 EWM26594.1 - 0.00016 21.9 2.1 0.00016 21.9 2.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1011) Nucleoside_tran PF01733.18 EWM26594.1 - 0.0011 18.5 0.1 0.0015 18.0 0.1 1.4 1 0 0 1 1 1 1 Nucleoside transporter DUF2318 PF10080.9 EWM26595.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) AA_kinase PF00696.28 EWM26596.1 - 5.4e-42 144.0 0.0 1.2e-41 142.9 0.0 1.6 1 0 0 1 1 1 1 Amino acid kinase family Homoserine_dh PF00742.19 EWM26596.1 - 3.2e-27 95.5 0.0 1.1e-23 84.1 0.0 3.0 3 0 0 3 3 3 2 Homoserine dehydrogenase NAD_binding_3 PF03447.16 EWM26596.1 - 8.4e-14 52.2 0.0 2.1e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ACT PF01842.25 EWM26596.1 - 1.6e-13 50.2 0.4 1.6e-05 24.6 0.1 2.8 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 EWM26596.1 - 1.4e-11 44.0 3.4 4.4e-05 23.2 0.1 3.5 3 0 0 3 3 3 2 ACT domain Tcp10_C PF07202.13 EWM26596.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 T-complex protein 10 C-terminus Dpy-30 PF05186.13 EWM26597.1 - 9.6e-18 63.6 0.1 1.3e-17 63.2 0.1 1.2 1 0 0 1 1 1 1 Dpy-30 motif Pex16 PF08610.10 EWM26598.1 - 1.6e-33 116.2 0.0 5.4e-33 114.5 0.0 1.8 1 1 0 1 1 1 1 Peroxisomal membrane protein (Pex16) RSRP PF17069.5 EWM26598.1 - 0.32 10.5 6.6 0.5 9.9 6.6 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 TH1 PF04858.13 EWM26599.1 - 1.9e-43 149.0 0.4 6.9e-30 104.2 0.0 2.3 3 0 0 3 3 3 2 TH1 protein GTP_EFTU PF00009.27 EWM26600.1 - 1e-70 237.3 0.0 1.5e-70 236.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EWM26600.1 - 1.1e-38 131.7 0.5 2.6e-38 130.5 0.5 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 EWM26600.1 - 8.1e-34 115.6 0.0 1.8e-33 114.5 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EWM26600.1 - 1.9e-28 98.3 0.4 1.3e-27 95.6 0.1 2.6 3 0 0 3 3 3 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EWM26600.1 - 2e-15 56.9 0.1 1.1e-14 54.5 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EWM26600.1 - 6.3e-06 26.0 0.0 1.5e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 EWM26600.1 - 0.0031 17.6 0.0 0.0067 16.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP-grasp_4 PF13535.6 EWM26600.1 - 0.039 13.6 0.2 0.12 12.0 0.2 1.8 1 0 0 1 1 1 0 ATP-grasp domain AIG1 PF04548.16 EWM26600.1 - 0.1 11.9 0.1 0.24 10.7 0.0 1.6 2 0 0 2 2 2 0 AIG1 family DUF4033 PF13225.6 EWM26601.1 - 5.3e-34 116.1 0.1 9.5e-34 115.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4033) WD40 PF00400.32 EWM26602.1 - 1.2e-05 26.0 3.4 0.009 16.9 0.0 5.7 7 0 0 7 7 7 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM26602.1 - 0.0011 19.2 0.0 1.2 9.5 0.0 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EWM26602.1 - 0.013 16.0 2.6 11 6.6 0.1 4.2 4 1 1 5 5 5 0 PQQ-like domain DUF2333 PF10095.9 EWM26605.1 - 0.089 11.8 6.8 0.16 11.0 6.8 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) Vac_Fusion PF02346.16 EWM26605.1 - 0.1 12.3 1.8 0.16 11.6 0.3 2.2 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 SNF2_N PF00176.23 EWM26606.1 - 1.1e-59 202.0 0.6 1.6e-59 201.4 0.6 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EWM26606.1 - 3.1e-18 66.1 0.0 1e-16 61.2 0.0 3.1 4 0 0 4 4 4 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 EWM26606.1 - 7.4e-07 28.6 0.0 9.7e-06 24.9 0.0 2.2 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 EWM26606.1 - 1.5e-06 28.1 0.0 3.6e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EWM26606.1 - 1.9e-05 24.8 0.0 3.4e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PHD PF00628.29 EWM26606.1 - 0.00028 20.7 13.2 0.00033 20.5 9.5 2.5 1 1 1 2 2 2 1 PHD-finger zf-PHD-like PF15446.6 EWM26606.1 - 0.0032 17.1 6.6 0.8 9.3 2.2 2.6 1 1 1 2 2 2 2 PHD/FYVE-zinc-finger like domain C5HCH PF17982.1 EWM26606.1 - 0.015 15.4 4.0 0.015 15.4 4.0 3.1 3 0 0 3 3 3 0 NSD Cys-His rich domain PHD_2 PF13831.6 EWM26606.1 - 0.046 13.3 3.7 0.11 12.0 3.7 1.7 1 0 0 1 1 1 0 PHD-finger Transketolase_N PF00456.21 EWM26607.1 - 4.1e-113 377.7 0.6 5.4e-113 377.3 0.6 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EWM26607.1 - 1.5e-36 125.8 0.0 2.7e-36 124.9 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EWM26607.1 - 5.1e-09 36.1 0.0 1.3e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 EWM26607.1 - 1.1e-07 31.4 0.1 4.7e-06 26.0 0.0 2.3 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 EWM26607.1 - 8.3e-06 25.0 0.6 1.3e-05 24.3 0.6 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 EWM26607.1 - 0.011 15.6 1.9 0.2 11.4 1.9 2.6 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain FHA PF00498.26 EWM26608.1 - 1.7e-10 41.1 0.1 7.1e-09 35.9 0.0 2.7 3 0 0 3 3 3 1 FHA domain RINGv PF12906.7 EWM26608.1 - 2.1e-10 40.6 4.8 3.8e-10 39.7 4.8 1.5 1 0 0 1 1 1 1 RING-variant domain Yop-YscD_cpl PF16697.5 EWM26608.1 - 0.00033 20.9 0.0 0.0021 18.3 0.0 2.3 3 0 0 3 3 3 1 Inner membrane component of T3SS, cytoplasmic domain PHD PF00628.29 EWM26608.1 - 0.31 11.0 5.3 0.55 10.2 5.3 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_3 PF13920.6 EWM26608.1 - 0.58 10.1 5.3 9 6.3 0.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EWM26608.1 - 0.95 9.3 3.6 3 7.7 3.6 1.9 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_2 PF13639.6 EWM26608.1 - 0.99 9.8 6.7 2.1 8.8 5.4 2.0 1 1 1 2 2 2 0 Ring finger domain FANCL_C PF11793.8 EWM26608.1 - 1.8 8.8 4.2 4.4 7.6 4.3 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain Kelch_3 PF13415.6 EWM26609.1 - 1.9e-27 95.0 12.2 1.3e-10 41.3 0.1 5.9 5 1 0 5 5 5 5 Galactose oxidase, central domain Kelch_2 PF07646.15 EWM26609.1 - 8e-25 85.8 2.3 5e-08 32.6 0.0 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 EWM26609.1 - 1.6e-24 85.2 4.3 2.7e-10 39.7 0.0 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 EWM26609.1 - 1.9e-24 85.4 1.0 4.5e-06 26.6 0.1 4.4 3 1 1 4 4 4 4 Galactose oxidase, central domain BTB PF00651.31 EWM26609.1 - 2.9e-24 85.4 0.0 9.3e-24 83.8 0.0 1.8 1 1 1 2 2 2 1 BTB/POZ domain Kelch_6 PF13964.6 EWM26609.1 - 5.3e-22 77.3 0.1 1.3e-07 31.7 0.0 4.4 3 1 1 4 4 4 4 Kelch motif Kelch_5 PF13854.6 EWM26609.1 - 4.1e-21 74.5 0.0 2.9e-08 33.5 0.0 3.9 4 0 0 4 4 4 3 Kelch motif HTH_20 PF12840.7 EWM26609.1 - 0.024 14.7 0.5 0.69 10.0 0.4 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain RICTOR_V PF14668.6 EWM26609.1 - 0.075 13.3 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, domain 5 MgtC PF02308.16 EWM26610.1 - 1.8e-29 102.5 9.7 3.4e-29 101.6 9.7 1.4 1 0 0 1 1 1 1 MgtC family Sensor PF13796.6 EWM26610.1 - 6.8 6.7 14.2 0.029 14.4 3.5 2.3 2 1 1 3 3 3 0 Putative sensor GRASP55_65 PF04495.14 EWM26611.1 - 2.4e-56 189.8 0.0 1.6e-41 141.9 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 EWM26611.1 - 5.7e-09 35.7 0.0 0.0021 17.8 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EWM26611.1 - 0.00015 22.0 0.0 0.28 11.5 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 EWM26611.1 - 0.034 14.5 0.0 3.3 8.1 0.0 2.3 2 0 0 2 2 2 0 PDZ domain EPSP_synthase PF00275.20 EWM26612.1 - 3.9e-99 332.2 0.0 4.6e-99 331.9 0.0 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) EPSP_synthase PF00275.20 EWM26613.1 - 3.9e-99 332.2 0.0 4.6e-99 331.9 0.0 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) GARS_A PF01071.19 EWM26614.1 - 4.4e-79 264.8 0.0 7.3e-79 264.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Formyl_trans_N PF00551.19 EWM26614.1 - 3.2e-43 147.6 0.0 5e-43 146.9 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase GARS_N PF02844.15 EWM26614.1 - 3.1e-34 117.6 0.1 7.2e-34 116.4 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 EWM26614.1 - 3.1e-27 94.7 1.1 1e-26 93.0 1.1 2.0 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain CPSase_L_D2 PF02786.17 EWM26614.1 - 4.8e-08 32.7 0.0 9.7e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.11 EWM26614.1 - 4.9e-05 23.0 0.0 0.00011 21.9 0.0 1.6 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 EWM26614.1 - 0.00024 21.2 0.0 0.00086 19.4 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 EWM26614.1 - 0.00031 20.3 0.0 0.00059 19.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 EWM26614.1 - 0.003 17.1 0.0 0.0057 16.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EWM26614.1 - 0.023 14.2 0.0 0.054 13.0 0.0 1.7 1 1 0 1 1 1 0 D-ala D-ala ligase C-terminus ATP-grasp_5 PF13549.6 EWM26614.1 - 0.035 13.6 0.0 0.084 12.3 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain Mito_carr PF00153.27 EWM26615.1 - 1.7e-66 220.2 3.7 2.9e-22 78.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PT-VENN PF04829.13 EWM26615.1 - 0.59 10.3 5.3 2.2 8.4 0.2 3.0 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif Thioredoxin_7 PF13899.6 EWM26616.1 - 1.5e-12 47.5 0.0 3.2e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 EWM26616.1 - 9.6e-06 25.3 0.0 2.4e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain LTV PF04180.14 EWM26617.1 - 8.8e-17 61.9 0.0 5.2e-15 56.1 0.0 2.7 1 1 0 1 1 1 1 Low temperature viability protein TPR_19 PF14559.6 EWM26618.1 - 1.3e-06 28.8 0.3 0.24 11.9 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EWM26618.1 - 1.7e-06 28.6 0.6 4.2e-05 24.1 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EWM26618.1 - 1.8e-06 28.2 2.8 0.6 11.1 0.0 5.0 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 EWM26618.1 - 3.8e-05 23.5 2.5 0.018 15.1 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EWM26618.1 - 0.00049 20.6 1.3 5.3 7.9 0.0 4.2 4 1 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EWM26618.1 - 0.0017 18.5 0.1 0.094 13.0 0.0 2.6 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EWM26618.1 - 0.0053 16.9 0.6 0.023 14.8 0.0 2.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EWM26618.1 - 0.016 15.0 0.2 0.32 10.9 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EWM26618.1 - 0.094 13.0 0.0 1.2 9.6 0.0 2.8 4 0 0 4 4 4 0 Tetratricopeptide repeat adh_short PF00106.25 EWM26619.1 - 1.9e-25 89.4 0.0 2.8e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EWM26619.1 - 4.8e-18 65.6 0.0 7e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM26619.1 - 1.8e-05 24.8 0.0 4.4e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 EWM26619.1 - 0.2 11.0 0.0 0.67 9.3 0.0 2.0 2 1 0 2 2 2 0 Fungal family of unknown function (DUF1776) DUF4211 PF13926.6 EWM26620.1 - 1.7e-16 60.5 4.6 1.7e-16 60.5 4.6 3.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4211) SPT6_acidic PF14632.6 EWM26620.1 - 0.016 15.7 11.2 0.016 15.7 11.2 8.2 7 2 1 8 8 8 0 Acidic N-terminal SPT6 TraF PF13728.6 EWM26620.1 - 0.15 11.8 2.2 0.39 10.5 2.2 1.7 1 0 0 1 1 1 0 F plasmid transfer operon protein NIF PF03031.18 EWM26621.1 - 1.9e-20 73.2 0.0 5.2e-20 71.8 0.0 1.7 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.7 EWM26621.1 - 4.1e-06 26.7 0.0 8e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 EWM26621.1 - 0.038 14.4 0.0 0.07 13.5 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain COX5B PF01215.19 EWM26622.1 - 2.4e-10 40.2 0.0 3.4e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Myb_DNA-binding PF00249.31 EWM26623.1 - 3.8e-08 33.4 0.0 7.9e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SSXT PF05030.12 EWM26623.1 - 8.4e-06 25.3 0.4 8.4e-06 25.3 0.4 2.7 2 0 0 2 2 2 1 SSXT protein (N-terminal region) Myb_DNA-bind_6 PF13921.6 EWM26623.1 - 0.0016 18.6 0.2 0.007 16.6 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EWM26623.1 - 0.068 13.1 0.0 0.34 10.8 0.0 2.2 1 0 0 1 1 1 0 Myb DNA-binding like Amidohydro_2 PF04909.14 EWM26624.1 - 3.2e-24 86.2 0.1 5.5e-24 85.4 0.1 1.5 1 1 0 1 1 1 1 Amidohydrolase CS PF04969.16 EWM26625.1 - 2.2e-05 25.4 0.0 3.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 CS domain NMO PF03060.15 EWM26626.1 - 6.5e-25 88.2 0.0 7.6e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EWM26626.1 - 8.1e-05 21.8 0.2 0.00013 21.1 0.2 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EWM26626.1 - 0.022 13.8 0.2 0.032 13.3 0.2 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Rad21_Rec8_N PF04825.13 EWM26627.1 - 3.6e-28 97.9 0.0 5.5e-28 97.3 0.0 1.2 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EWM26627.1 - 7.7e-11 41.1 0.0 1.4e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein tRNA-synt_1_2 PF13603.6 EWM26628.1 - 4.4e-62 208.9 0.0 7e-62 208.2 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1 PF00133.22 EWM26628.1 - 3.7e-60 203.9 0.0 1.7e-37 129.0 0.0 3.9 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EWM26628.1 - 1e-23 83.8 0.0 9.2e-15 54.3 0.0 3.3 4 0 0 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EWM26628.1 - 1.1e-16 61.2 0.0 2.9e-16 59.8 0.0 1.8 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EWM26628.1 - 0.00043 19.7 0.0 0.0023 17.3 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.25 EWM26628.1 - 0.047 13.0 0.0 0.092 12.0 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) tRNA-synt_1f PF01921.18 EWM26628.1 - 0.056 12.4 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (K) tRNA-synt_1d PF00750.19 EWM26628.1 - 0.16 10.9 0.0 0.33 9.9 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (R) HA2 PF04408.23 EWM26630.1 - 8.6e-21 74.3 0.0 8.6e-21 74.3 0.0 4.7 6 0 0 6 6 6 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EWM26630.1 - 1.6e-14 54.0 0.0 6.5e-14 52.1 0.0 2.1 1 1 1 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EWM26630.1 - 1.7e-11 44.5 0.0 3.5e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EWM26630.1 - 2.4e-06 27.4 0.1 1e-05 25.4 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EWM26630.1 - 4.4e-05 23.8 0.0 0.00016 22.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EWM26630.1 - 0.0021 17.8 0.0 0.0048 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EWM26630.1 - 0.013 14.6 0.0 0.027 13.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 EWM26630.1 - 0.022 15.1 0.1 0.05 13.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain Radical_SAM PF04055.21 EWM26630.1 - 0.032 14.6 0.2 0.12 12.7 0.1 2.0 2 0 0 2 2 2 0 Radical SAM superfamily AAA_23 PF13476.6 EWM26630.1 - 0.079 13.5 0.0 0.079 13.5 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 EWM26630.1 - 0.09 12.9 2.6 0.11 12.7 0.0 2.6 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 EWM26630.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Flavi_DEAD PF07652.14 EWM26630.1 - 0.14 12.1 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 Flavivirus DEAD domain Sigma54_activ_2 PF14532.6 EWM26630.1 - 0.15 12.2 0.0 0.55 10.3 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.6 EWM26630.1 - 0.19 11.8 0.1 1.6 8.8 0.1 2.2 1 1 0 1 1 1 0 AAA domain adh_short PF00106.25 EWM26631.1 - 1.4e-34 119.3 0.0 1.9e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EWM26631.1 - 1.6e-24 86.8 0.0 2.4e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM26631.1 - 0.13 12.1 0.5 0.35 10.8 0.5 1.8 1 1 0 1 1 1 0 KR domain DUF4349 PF14257.6 EWM26634.1 - 0.12 11.7 0.2 0.12 11.7 0.2 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4349) PPP4R2 PF09184.11 EWM26634.1 - 1.3 8.6 12.4 1.9 8.0 12.4 1.2 1 0 0 1 1 1 0 PPP4R2 Pkinase PF00069.25 EWM26635.1 - 3.4e-40 138.1 0.0 4.8e-40 137.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM26635.1 - 2.4e-37 128.6 0.0 3e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EWM26635.1 - 3.6e-05 23.8 0.0 0.04 13.8 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family LigB PF02900.18 EWM26635.1 - 0.0086 15.2 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Haspin_kinase PF12330.8 EWM26635.1 - 0.043 12.7 0.0 1.6 7.6 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain Trypan_PARP PF05887.11 EWM26635.1 - 4.8 7.2 13.2 8.1 6.4 13.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF21 PF01595.20 EWM26637.1 - 4e-33 114.6 0.1 5.9e-33 114.0 0.1 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 EWM26637.1 - 0.00015 22.1 0.0 0.0014 19.0 0.0 2.6 2 1 0 2 2 2 1 CBS domain YrhC PF14143.6 EWM26637.1 - 0.048 13.8 2.7 0.11 12.6 2.7 1.5 1 0 0 1 1 1 0 YrhC-like protein MAGE_N PF12440.8 EWM26637.1 - 0.24 12.1 7.4 0.65 10.7 7.4 1.7 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal SUIM_assoc PF16619.5 EWM26637.1 - 0.35 11.0 4.2 0.85 9.7 4.2 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 ABC2_membrane PF01061.24 EWM26638.1 - 2.5e-23 82.6 25.3 2.5e-23 82.6 25.3 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 EWM26638.1 - 6.2e-21 75.4 0.0 9.6e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EWM26638.1 - 1e-07 32.1 0.0 0.014 15.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EWM26638.1 - 8.8e-05 23.1 0.2 0.00016 22.2 0.2 1.3 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 EWM26638.1 - 0.00011 21.7 0.0 0.00089 18.8 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EWM26638.1 - 0.001 19.5 0.1 0.002 18.5 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EWM26638.1 - 0.0011 19.3 0.0 0.011 16.0 0.1 2.6 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EWM26638.1 - 0.0084 16.0 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EWM26638.1 - 0.023 14.4 0.2 0.053 13.3 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 EWM26638.1 - 0.039 13.2 0.0 0.076 12.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Rad17 PF03215.15 EWM26638.1 - 0.063 13.2 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_28 PF13521.6 EWM26638.1 - 0.08 13.2 0.1 0.49 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EWM26638.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 EWM26638.1 - 0.13 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Methyltransf_28 PF02636.17 EWM26639.1 - 1.8e-66 224.4 0.0 9.1e-66 222.2 0.0 1.9 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase LisH PF08513.11 EWM26640.1 - 0.0072 16.2 0.1 0.019 14.9 0.1 1.8 1 0 0 1 1 1 1 LisH Abhydrolase_1 PF00561.20 EWM26641.1 - 4e-17 62.7 0.1 2.7e-14 53.4 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EWM26641.1 - 1.1e-15 58.8 6.5 1.1e-15 58.8 6.5 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EWM26641.1 - 1.5e-13 50.6 0.0 3.6e-13 49.3 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EWM26641.1 - 4.4e-05 23.7 0.1 0.046 13.8 0.1 2.6 2 1 1 3 3 3 2 Thioesterase domain Esterase PF00756.20 EWM26641.1 - 0.00033 20.4 0.0 0.00049 19.8 0.0 1.2 1 0 0 1 1 1 1 Putative esterase EHN PF06441.12 EWM26641.1 - 0.03 14.7 0.0 1.3 9.4 0.0 2.2 2 0 0 2 2 2 0 Epoxide hydrolase N terminus Abhydrolase_3 PF07859.13 EWM26641.1 - 0.03 14.2 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EWM26641.1 - 0.093 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein DUF2048 PF09752.9 EWM26641.1 - 0.2 10.7 0.0 0.3 10.1 0.0 1.1 1 0 0 1 1 1 0 Abhydrolase domain containing 18 DUF4050 PF13259.6 EWM26644.1 - 4.7e-06 27.0 0.0 8.1e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) DUF2721 PF11026.8 EWM26645.1 - 0.14 12.1 6.8 1 9.3 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) HEAT PF02985.22 EWM26646.1 - 0.021 15.1 0.1 0.14 12.5 0.0 2.6 2 0 0 2 2 2 0 HEAT repeat Cnd1 PF12717.7 EWM26646.1 - 0.076 13.1 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 His_biosynth PF00977.21 EWM26649.1 - 2.1e-45 154.9 0.0 4.1e-31 108.2 0.0 2.7 2 1 0 2 2 2 2 Histidine biosynthesis protein GATase PF00117.28 EWM26649.1 - 2.6e-16 59.9 0.0 4.3e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 EWM26649.1 - 0.0012 18.7 0.0 0.36 10.6 0.0 2.4 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 EWM26649.1 - 0.085 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain AhpC-TSA_2 PF13911.6 EWM26651.1 - 2.8e-08 33.9 0.1 4.8e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme MMR_HSR1 PF01926.23 EWM26652.1 - 2.4e-15 56.6 0.0 7.3e-15 55.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EWM26652.1 - 5e-07 29.4 0.0 1.2e-06 28.1 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EWM26652.1 - 4e-06 27.0 0.1 0.0017 18.5 0.0 2.9 2 1 1 3 3 3 2 Dynamin family AIG1 PF04548.16 EWM26652.1 - 2.8e-05 23.5 0.0 8.4e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 AIG1 family EnY2 PF10163.9 EWM26653.1 - 0.19 12.1 0.2 0.19 12.1 0.2 1.8 2 1 0 2 2 2 0 Transcription factor e(y)2 WD40 PF00400.32 EWM26654.1 - 3.5e-27 94.1 7.1 1.5e-06 28.8 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM26654.1 - 0.00024 21.3 0.0 0.53 10.6 0.0 4.2 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_21 PF09976.9 EWM26655.1 - 0.019 14.7 0.5 0.022 14.5 0.5 1.0 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain UPF0160 PF03690.13 EWM26656.1 - 8e-123 410.1 0.0 9e-123 409.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) TIM PF00121.18 EWM26658.1 - 2.7e-77 259.4 0.0 3.1e-77 259.2 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Acyl_transf_1 PF00698.21 EWM26659.1 - 6.5e-53 180.3 0.0 1.1e-52 179.5 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 EWM26659.1 - 1.7e-47 161.7 1.4 3.5e-45 154.1 0.1 3.3 3 0 0 3 3 3 1 KR domain ketoacyl-synt PF00109.26 EWM26659.1 - 3.3e-41 141.5 0.1 7.4e-41 140.4 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EWM26659.1 - 1.1e-27 96.4 0.1 3.3e-27 94.8 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 EWM26659.1 - 3.4e-22 78.8 0.0 1.4e-21 76.8 0.0 2.1 1 0 0 1 1 1 1 Male sterility protein ADH_zinc_N PF00107.26 EWM26659.1 - 1.6e-19 70.1 0.1 1.5e-18 67.1 0.0 2.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EWM26659.1 - 5.5e-17 63.1 0.0 2.4e-16 61.0 0.0 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EWM26659.1 - 1.3e-16 60.6 0.1 2.7e-14 53.1 0.0 3.3 3 0 0 3 3 3 1 short chain dehydrogenase KAsynt_C_assoc PF16197.5 EWM26659.1 - 1.8e-10 41.2 0.0 4.1e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short_C2 PF13561.6 EWM26659.1 - 4.4e-10 39.5 0.7 6.1e-09 35.8 0.0 2.9 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase PS-DH PF14765.6 EWM26659.1 - 8.3e-10 38.4 0.0 2.3e-09 36.9 0.0 1.7 1 1 0 1 1 1 1 Polyketide synthase dehydratase Epimerase PF01370.21 EWM26659.1 - 7e-08 32.2 0.0 0.0092 15.5 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EWM26659.1 - 6.8e-07 29.5 0.1 2.4e-06 27.8 0.1 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 EWM26659.1 - 7.9e-06 25.4 0.2 3.3e-05 23.4 0.1 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain ADH_N PF08240.12 EWM26659.1 - 9.1e-06 25.5 0.0 3.3e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Polysacc_synt_2 PF02719.15 EWM26659.1 - 0.00039 19.6 0.0 0.0016 17.6 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein ACP_syn_III PF08545.10 EWM26659.1 - 0.011 15.6 0.7 0.033 14.0 0.7 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GDP_Man_Dehyd PF16363.5 EWM26659.1 - 0.017 14.6 0.0 0.046 13.1 0.0 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Acetyltransf_1 PF00583.25 EWM26660.1 - 1.4e-16 60.8 0.0 1.9e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EWM26660.1 - 7.9e-11 42.0 0.4 1.1e-10 41.5 0.4 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EWM26660.1 - 1.2e-09 38.5 0.1 2e-09 37.8 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EWM26660.1 - 6.9e-08 32.4 0.1 1.9e-07 31.0 0.1 1.7 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_4 PF13420.7 EWM26660.1 - 0.00029 21.0 0.3 0.00043 20.5 0.3 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EWM26660.1 - 0.0095 16.0 0.1 0.015 15.4 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EWM26660.1 - 0.017 15.8 0.0 0.029 15.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 EWM26660.1 - 0.061 13.0 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ XAF1_C PF18608.1 EWM26660.1 - 0.11 12.1 0.2 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 XIAP-associated factor 1 C-terminal domain Acetyltransf_13 PF13880.6 EWM26660.1 - 0.12 12.4 0.1 0.39 10.7 0.1 1.9 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase Cellulase PF00150.18 EWM26661.1 - 1.5e-34 119.7 4.1 2e-34 119.3 4.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TPR_19 PF14559.6 EWM26664.1 - 2.2e-11 44.1 0.1 1.1e-05 25.9 0.0 4.7 2 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EWM26664.1 - 6.5e-07 29.6 9.1 0.0032 18.2 0.0 5.0 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EWM26664.1 - 0.00014 22.5 11.7 0.058 14.0 0.0 3.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EWM26664.1 - 0.00016 21.5 4.1 0.022 14.8 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 EWM26664.1 - 0.00041 20.5 2.3 0.081 13.3 0.1 4.0 5 1 0 5 5 4 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 EWM26664.1 - 0.012 15.5 0.4 0.33 10.8 0.1 2.4 1 1 1 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal TPR_12 PF13424.6 EWM26664.1 - 0.013 15.7 9.7 0.43 10.9 0.3 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 EWM26664.1 - 0.022 14.9 1.3 0.05 13.7 0.0 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EWM26664.1 - 0.079 13.2 1.3 0.38 11.1 0.1 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EWM26664.1 - 0.18 11.7 1.7 4.3 7.3 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EWM26664.1 - 3.4 8.5 8.7 36 5.3 0.0 5.0 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF1350 PF07082.11 EWM26665.1 - 1.1e-51 175.6 0.2 2.5e-34 118.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1350) GCV_T PF01571.21 EWM26666.1 - 5e-80 268.6 0.0 6.2e-80 268.3 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 EWM26666.1 - 1.4e-18 66.6 0.1 2.9e-18 65.5 0.1 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 EWM26666.1 - 2.1e-05 24.7 0.0 4.7e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 Sarcosine oxidase, gamma subunit family Sulfate_transp PF00916.20 EWM26667.1 - 3.2e-19 68.9 20.1 3.2e-19 68.9 20.1 1.5 2 0 0 2 2 2 1 Sulfate permease family cNMP_binding PF00027.29 EWM26667.1 - 2.4e-12 46.8 0.0 4.3e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 EWM26667.1 - 4.8e-08 32.6 0.0 1.1e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 STAS domain Glyco_transf_90 PF05686.12 EWM26669.1 - 2e-32 112.6 0.0 3e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 EWM26669.1 - 0.19 12.2 0.5 0.47 10.9 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferases group 1 CitMHS PF03600.16 EWM26670.1 - 5e-31 108.0 20.8 5e-31 108.0 20.8 1.5 2 0 0 2 2 2 1 Citrate transporter CBS PF00571.28 EWM26670.1 - 3.1e-12 46.7 1.3 1.1e-06 28.9 0.6 2.7 2 0 0 2 2 2 2 CBS domain zf-C2H2_6 PF13912.6 EWM26671.1 - 0.037 14.0 0.6 0.037 14.0 0.6 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HE PF16278.5 EWM26671.1 - 0.38 11.2 1.8 4.5 7.8 0.2 2.6 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2 PF00096.26 EWM26671.1 - 1.2 9.7 9.3 11 6.8 2.1 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EWM26671.1 - 9.3 7.4 9.6 20 6.4 0.3 3.3 2 0 0 2 2 2 0 C2H2-type zinc finger Shugoshin_N PF07558.11 EWM26672.1 - 0.01 15.7 2.0 2.8 7.9 0.0 4.4 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region PLDc_N PF13396.6 EWM26673.1 - 1.7e-07 31.0 1.9 2.9e-07 30.3 1.9 1.4 1 1 0 1 1 1 1 Phospholipase_D-nuclease N-terminal DUF4396 PF14342.6 EWM26673.1 - 0.073 13.4 0.0 0.1 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4396) cobW PF02492.19 EWM26674.1 - 2.7e-50 170.4 0.1 4.1e-50 169.8 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EWM26674.1 - 1.2e-05 25.1 0.0 3.9e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain Viral_helicase1 PF01443.18 EWM26674.1 - 0.0032 17.3 0.1 0.24 11.1 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 EWM26674.1 - 0.0033 17.4 0.1 0.74 9.7 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 EWM26674.1 - 0.0038 17.3 0.0 0.0099 16.0 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EWM26674.1 - 0.015 15.7 0.0 0.031 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 EWM26674.1 - 0.021 13.9 0.1 0.035 13.2 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 EWM26674.1 - 0.047 14.0 0.0 0.092 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EWM26674.1 - 0.058 13.1 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EWM26674.1 - 0.071 13.6 0.3 0.13 12.7 0.3 1.4 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 EWM26674.1 - 0.098 12.1 0.1 0.23 10.9 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_33 PF13671.6 EWM26674.1 - 0.14 12.3 0.2 0.86 9.8 0.1 2.1 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 EWM26674.1 - 0.16 11.9 0.2 0.67 9.9 0.1 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATPase_2 PF01637.18 EWM26674.1 - 0.19 11.7 0.0 0.31 10.9 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 EWM26674.1 - 0.19 11.7 0.1 0.37 10.7 0.1 1.5 1 0 0 1 1 1 0 NACHT domain Sad1_UNC PF07738.13 EWM26675.1 - 5.7e-11 42.6 0.0 1.2e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF641 PF04859.12 EWM26675.1 - 0.11 12.8 19.0 2.5 8.5 0.2 3.7 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) Mating_N PF12731.7 EWM26675.1 - 0.46 10.6 5.2 0.19 11.8 0.3 3.0 3 0 0 3 3 3 0 Mating-type protein beta 1 DUF1664 PF07889.12 EWM26675.1 - 2.5 8.2 23.3 1.7 8.7 4.5 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 EWM26675.1 - 4 7.5 27.3 0.25 11.3 2.2 4.5 1 1 2 4 4 4 0 Laminin Domain II Spc7 PF08317.11 EWM26675.1 - 4.3 6.1 39.9 2.2 7.1 15.0 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein Pox_MCEL PF03291.16 EWM26676.1 - 1.3e-36 126.4 0.0 5.6e-32 111.2 0.0 2.7 2 1 0 2 2 2 2 mRNA capping enzyme NIF PF03031.18 EWM26676.1 - 4.9e-16 58.9 0.0 8.3e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Methyltransf_25 PF13649.6 EWM26676.1 - 2.1e-05 25.1 0.1 0.00066 20.3 0.1 2.8 1 1 0 1 1 1 1 Methyltransferase domain mRNA_cap_C PF03919.15 EWM26676.1 - 9.6e-05 23.0 0.0 0.00021 21.9 0.0 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain mRNA_cap_enzyme PF01331.19 EWM26676.1 - 0.00019 21.3 0.0 0.0014 18.5 0.0 2.2 2 1 0 2 2 2 1 mRNA capping enzyme, catalytic domain Methyltransf_11 PF08241.12 EWM26676.1 - 0.003 18.2 0.0 0.019 15.6 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Ank_4 PF13637.6 EWM26677.1 - 6.2e-16 58.5 0.1 1.2e-06 29.0 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EWM26677.1 - 8.3e-15 54.7 0.0 2.1e-12 47.0 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EWM26677.1 - 2.6e-13 49.8 0.2 2.8e-05 24.3 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EWM26677.1 - 1.5e-11 44.7 0.0 7.1e-11 42.6 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EWM26677.1 - 1.3e-07 31.3 0.0 0.00033 20.9 0.0 3.9 3 1 0 3 3 3 1 Ankyrin repeat SCAB-PH PF17684.1 EWM26678.1 - 0.038 14.2 0.0 0.044 14.0 0.0 1.3 1 0 0 1 1 1 0 PH domain of plant-specific actin-binding protein Pik1 PF11522.8 EWM26679.1 - 0.073 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Yeast phosphatidylinositol-4-OH kinase Pik1 DUF1180 PF06679.12 EWM26679.1 - 10 6.5 6.0 48 4.3 6.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Ras PF00071.22 EWM26680.1 - 1.9e-62 209.6 0.1 2.3e-62 209.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EWM26680.1 - 1.2e-35 122.4 0.1 1.9e-35 121.7 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EWM26680.1 - 2.4e-16 59.7 0.0 3e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EWM26680.1 - 2.7e-06 27.5 0.0 4.9e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EWM26680.1 - 7.9e-06 25.5 0.1 3.7e-05 23.4 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EWM26680.1 - 0.00013 21.4 0.0 0.00016 21.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EWM26680.1 - 0.00029 20.8 0.1 0.43 10.5 0.0 2.7 1 1 1 3 3 3 2 RsgA GTPase SRPRB PF09439.10 EWM26680.1 - 0.00091 18.7 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit CENP-M PF11111.8 EWM26680.1 - 0.0027 16.9 0.0 0.0039 16.4 0.0 1.2 1 0 0 1 1 1 1 Centromere protein M (CENP-M) AAA_22 PF13401.6 EWM26680.1 - 0.0078 16.5 0.0 0.015 15.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.18 EWM26680.1 - 0.046 13.2 0.0 0.44 10.1 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.6 EWM26680.1 - 0.062 13.7 0.0 0.083 13.3 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 EWM26680.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DAP3 PF10236.9 EWM26680.1 - 0.13 11.4 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 HCO3_cotransp PF00955.21 EWM26681.1 - 2.8e-140 468.5 11.0 3.9e-73 247.0 1.3 2.1 1 1 1 2 2 2 2 HCO3- transporter family PRKCSH_1 PF13015.6 EWM26682.1 - 3.5e-24 85.3 0.4 6.1e-24 84.5 0.4 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH-like PF12999.7 EWM26682.1 - 2e-18 66.8 3.5 4e-18 65.8 3.5 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH PF07915.13 EWM26682.1 - 0.0079 17.2 0.1 0.024 15.6 0.1 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Zip PF02535.22 EWM26683.1 - 1.1e-58 199.0 4.2 1.4e-58 198.7 4.2 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter LptF_LptG PF03739.14 EWM26683.1 - 0.036 12.9 1.0 0.07 12.0 1.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Gp_dh_C PF02800.20 EWM26684.1 - 8.3e-70 233.4 0.0 1.3e-69 232.8 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EWM26684.1 - 1.5e-15 57.3 0.1 3.6e-15 56.1 0.1 1.6 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Peptidase_M48_N PF16491.5 EWM26686.1 - 3.3e-57 193.3 0.0 3.3e-57 193.3 0.0 1.7 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 EWM26686.1 - 8.8e-43 146.4 0.1 1.2e-31 110.0 0.1 2.5 2 0 0 2 2 2 2 Peptidase family M48 SprT-like PF10263.9 EWM26686.1 - 0.038 13.8 0.0 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 SprT-like family DUF900 PF05990.12 EWM26686.1 - 0.14 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PPR_2 PF13041.6 EWM26689.1 - 3.2e-55 184.1 0.0 2.3e-08 34.1 0.0 14.9 12 3 3 15 15 15 10 PPR repeat family PPR PF01535.20 EWM26689.1 - 7.6e-38 126.1 10.7 0.0048 17.0 0.0 18.1 19 0 0 19 19 19 6 PPR repeat PPR_3 PF13812.6 EWM26689.1 - 6e-33 112.7 0.0 1.2e-08 34.9 0.0 10.9 9 3 2 11 11 11 6 Pentatricopeptide repeat domain PPR_1 PF12854.7 EWM26689.1 - 1e-30 105.1 3.3 0.0009 18.9 0.0 12.9 13 0 0 13 13 13 6 PPR repeat PPR_long PF17177.4 EWM26689.1 - 4.4e-23 81.8 2.9 2.6e-06 27.0 0.1 6.0 6 0 0 6 6 6 4 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 EWM26689.1 - 2.3e-05 24.9 46.7 1.6 9.8 0.1 14.9 14 2 2 16 16 15 2 Tetratricopeptide repeat TPR_19 PF14559.6 EWM26689.1 - 0.0068 16.9 9.5 39 4.8 0.0 8.5 11 1 1 12 12 12 0 Tetratricopeptide repeat Ank_5 PF13857.6 EWM26689.1 - 0.012 15.9 0.1 3.5 8.1 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeats (many copies) DUF3368 PF11848.8 EWM26689.1 - 0.028 14.2 1.3 17 5.3 0.1 5.1 5 1 1 6 6 6 0 Domain of unknown function (DUF3368) ATP13 PF12921.7 EWM26689.1 - 0.06 13.2 0.0 31 4.4 0.0 3.5 4 0 0 4 4 4 0 Mitochondrial ATPase expression TPR_7 PF13176.6 EWM26689.1 - 0.079 13.0 13.9 8.7 6.6 0.0 6.9 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 EWM26689.1 - 0.086 12.7 17.3 0.51 10.3 0.1 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EWM26689.1 - 0.097 12.3 8.1 3.2 7.4 0.1 6.1 6 1 1 7 7 7 0 Bacterial type III secretion protein (HrpB1_HrpK) MRP-S27 PF10037.9 EWM26689.1 - 0.18 10.6 0.0 14 4.4 0.0 3.1 3 0 0 3 3 3 0 Mitochondrial 28S ribosomal protein S27 TPR_2 PF07719.17 EWM26689.1 - 0.93 9.8 8.6 3.1 8.1 0.1 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 EWM26689.1 - 8.5 6.7 12.5 8.2 6.8 0.0 6.4 8 0 0 8 8 6 0 Tetratricopeptide repeat Archease PF01951.16 EWM26690.1 - 1.2e-45 155.1 0.1 2.4e-45 154.1 0.1 1.5 2 0 0 2 2 2 1 Archease protein family (MTH1598/TM1083) COPI_assoc PF08507.10 EWM26691.1 - 8.1e-06 25.9 4.1 1.4e-05 25.2 4.1 1.3 1 0 0 1 1 1 1 COPI associated protein TMEM100 PF16311.5 EWM26691.1 - 1.5 8.4 4.3 21 4.7 0.5 2.6 2 1 0 2 2 2 0 Transmembrane protein 100 HABP4_PAI-RBP1 PF04774.15 EWM26693.1 - 5.7e-07 30.4 5.2 8.8e-07 29.8 5.2 1.3 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family DUF2231 PF09990.9 EWM26696.1 - 7.4e-13 48.8 7.8 7.4e-13 48.8 7.8 1.7 2 0 0 2 2 2 1 Predicted membrane protein (DUF2231) JAMP PF05571.12 EWM26696.1 - 0.12 12.0 0.5 0.16 11.5 0.5 1.2 1 0 0 1 1 1 0 JNK1/MAPK8-associated membrane protein DUF5357 PF17310.2 EWM26696.1 - 0.5 8.9 3.9 0.61 8.6 3.7 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5357) TMEM100 PF16311.5 EWM26696.1 - 1.3 8.6 3.1 1.6 8.3 0.8 1.9 1 1 1 2 2 2 0 Transmembrane protein 100 Metallophos PF00149.28 EWM26697.1 - 6.2e-12 46.4 0.0 8.2e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EWM26697.1 - 6.3e-07 29.7 0.0 9.6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 EWM26697.1 - 0.074 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Zn_clus PF00172.18 EWM26698.1 - 7.6e-09 35.6 11.0 1.4e-08 34.7 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MaoC_dehydratas PF01575.19 EWM26699.1 - 1.2e-14 53.9 0.1 2.2e-14 53.1 0.1 1.4 1 0 0 1 1 1 1 MaoC like domain Exo_endo_phos PF03372.23 EWM26700.1 - 4.4e-06 26.4 0.0 2.3e-05 24.0 0.0 2.4 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family RRM_1 PF00076.22 EWM26701.1 - 4.5e-15 55.2 0.0 7.3e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EWM26701.1 - 0.046 13.6 0.0 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif ApoLp-III PF07464.11 EWM26702.1 - 0.0054 16.8 1.3 2.2 8.4 0.0 2.7 3 0 0 3 3 3 2 Apolipophorin-III precursor (apoLp-III) HTH_25 PF13413.6 EWM26702.1 - 0.014 15.2 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Gly_transf_sug PF04488.15 EWM26702.1 - 0.074 13.7 0.1 0.81 10.3 0.0 2.4 2 0 0 2 2 2 0 Glycosyltransferase sugar-binding region containing DXD motif Pyr_redox_2 PF07992.14 EWM26703.1 - 1.9e-57 194.8 2.6 2.7e-57 194.2 2.6 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EWM26703.1 - 3.3e-31 107.8 0.3 1.1e-30 106.2 0.3 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EWM26703.1 - 3.3e-13 50.0 2.2 1.7e-12 47.7 0.0 3.1 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EWM26703.1 - 4.8e-07 29.2 4.7 0.0023 17.1 2.3 2.4 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.22 EWM26703.1 - 5.8e-07 28.9 4.1 3.1e-06 26.5 1.5 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EWM26703.1 - 0.0044 16.4 2.0 0.0069 15.8 2.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 EWM26703.1 - 0.016 15.1 0.3 0.94 9.3 0.0 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K_oxygenase PF13434.6 EWM26703.1 - 0.017 14.3 0.1 0.06 12.5 0.0 1.9 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) UDPG_MGDP_dh_N PF03721.14 EWM26703.1 - 0.023 14.3 0.0 0.051 13.1 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_8 PF13450.6 EWM26703.1 - 0.11 12.7 3.2 7.7 6.8 2.3 2.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain PseudoU_synth_2 PF00849.22 EWM26704.1 - 2.6e-26 92.6 0.0 1.3e-25 90.3 0.0 2.0 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 EWM26704.1 - 0.0018 17.9 0.1 0.0037 17.0 0.1 1.5 1 0 0 1 1 1 1 S4 domain Shisa PF13908.6 EWM26705.1 - 1.5e-05 25.4 0.1 2.5e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Comm PF15957.5 EWM26705.1 - 0.033 14.5 0.0 0.053 13.9 0.0 1.3 1 0 0 1 1 1 0 Commissureless FAP PF07174.11 EWM26705.1 - 1.8 8.0 15.9 2.6 7.4 15.9 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) adh_short PF00106.25 EWM26706.1 - 1.8e-34 118.9 0.0 2.6e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EWM26706.1 - 7.8e-24 84.5 0.0 1.1e-23 84.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EWM26706.1 - 2.6e-05 24.2 0.0 9.4e-05 22.4 0.0 1.9 3 0 0 3 3 3 1 NAD(P)H-binding KR PF08659.10 EWM26706.1 - 0.00096 19.1 0.0 0.0019 18.1 0.0 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EWM26706.1 - 0.0083 15.6 0.0 0.17 11.3 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EWM26706.1 - 0.01 14.9 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.8 EWM26706.1 - 0.022 14.5 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_hydro_12 PF01670.16 EWM26706.1 - 0.097 12.7 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 12 FBPase PF00316.20 EWM26707.1 - 0.18 11.2 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain EGF_2 PF07974.13 EWM26708.1 - 0.0041 17.4 11.5 0.0041 17.4 11.5 1.9 2 0 0 2 2 2 1 EGF-like domain EGF PF00008.27 EWM26708.1 - 0.16 12.3 9.9 0.32 11.3 9.9 1.6 1 0 0 1 1 1 0 EGF-like domain FKBP_C PF00254.28 EWM26709.1 - 1.1e-17 64.1 0.0 2.5e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PDZ PF00595.24 EWM26709.1 - 1.1e-05 25.7 0.5 2.4e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EWM26709.1 - 0.0042 16.9 0.1 0.013 15.4 0.1 1.9 1 0 0 1 1 1 1 PDZ domain Ank_3 PF13606.6 EWM26710.1 - 4e-13 48.3 0.1 0.0028 18.0 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 EWM26710.1 - 4.2e-13 49.1 0.5 0.00031 21.0 0.1 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EWM26710.1 - 3.9e-12 46.2 0.4 1.1e-06 28.8 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EWM26710.1 - 4.6e-12 46.4 0.0 1.4e-05 25.6 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EWM26710.1 - 1.9e-10 41.1 0.4 2e-07 31.4 0.3 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Glyco_transf_22 PF03901.17 EWM26712.1 - 3.6e-76 257.1 8.3 5e-76 256.6 8.3 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family LmjF365940-deam PF14421.6 EWM26712.1 - 0.0015 18.2 0.0 0.003 17.2 0.0 1.5 1 0 0 1 1 1 1 A distinct subfamily of CDD/CDA-like deaminases SelK_SelG PF10961.8 EWM26712.1 - 0.0069 17.0 0.3 0.12 13.1 0.6 2.3 2 0 0 2 2 2 1 Selenoprotein SelK_SelG dCMP_cyt_deam_1 PF00383.23 EWM26712.1 - 0.068 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region Mur_ligase_M PF08245.12 EWM26713.1 - 4.7e-07 30.0 0.1 1e-06 28.9 0.0 1.5 2 0 0 2 2 2 1 Mur ligase middle domain DLIC PF05783.11 EWM26714.1 - 4.8e-29 101.5 0.0 3.6e-20 72.3 0.0 4.2 4 0 0 4 4 4 3 Dynein light intermediate chain (DLIC) Roc PF08477.13 EWM26714.1 - 0.0021 18.3 0.0 0.0056 16.9 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 EWM26714.1 - 0.021 15.2 0.0 0.044 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Ras PF00071.22 EWM26714.1 - 0.025 14.2 0.0 0.29 10.7 0.0 2.1 2 0 0 2 2 2 0 Ras family TniB PF05621.11 EWM26714.1 - 0.029 13.8 0.0 1.5 8.2 0.0 2.6 3 0 0 3 3 3 0 Bacterial TniB protein TLD PF07534.16 EWM26715.1 - 1.8e-29 102.7 0.6 1.3e-13 51.4 0.0 2.4 2 0 0 2 2 2 2 TLD Chlor_dismutase PF06778.12 EWM26715.1 - 0.038 13.6 0.1 0.075 12.6 0.1 1.4 1 0 0 1 1 1 0 Chlorite dismutase DUF1211 PF06736.11 EWM26716.1 - 1.2e-15 57.7 0.3 2.1e-11 44.1 0.0 3.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1211) DUF1211 PF06736.11 EWM26717.1 - 6.8e-25 87.3 2.5 2.5e-11 43.8 0.0 3.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1211) DUF1211 PF06736.11 EWM26718.1 - 3.7e-13 49.7 0.0 1.9e-11 44.2 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1211) FGGY_C PF02782.16 EWM26719.1 - 5.7e-26 91.5 0.3 1e-25 90.7 0.3 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EWM26719.1 - 2e-10 40.7 0.0 1.3e-05 24.9 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain ERGIC_N PF13850.6 EWM26719.1 - 0.17 12.3 0.0 0.33 11.3 0.0 1.4 1 0 0 1 1 1 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Peptidase_S49 PF01343.18 EWM26720.1 - 5.8e-56 188.7 0.0 8.2e-37 126.5 0.0 2.3 2 0 0 2 2 2 2 Peptidase family S49 TadZ_N PF16968.5 EWM26720.1 - 0.074 12.7 0.3 3.2 7.4 0.2 2.4 2 0 0 2 2 2 0 Pilus assembly protein TadZ N-terminal DUF4119 PF13494.6 EWM26720.1 - 0.18 11.9 0.0 0.39 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF4119) ECH_1 PF00378.20 EWM26720.1 - 0.18 11.0 2.3 3.1 7.0 0.9 2.8 2 1 0 2 2 2 0 Enoyl-CoA hydratase/isomerase Ribosomal_L22 PF00237.19 EWM26721.1 - 9.5e-21 74.0 0.2 1.3e-20 73.6 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF262 PF03235.14 EWM26722.1 - 0.00042 20.6 0.0 0.00071 19.8 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function DUF262 DndB PF14072.6 EWM26722.1 - 0.019 14.2 0.2 0.05 12.8 0.0 1.7 1 1 1 2 2 2 0 DNA-sulfur modification-associated ParBc PF02195.18 EWM26722.1 - 0.022 15.0 0.0 0.049 13.9 0.0 1.6 1 0 0 1 1 1 0 ParB-like nuclease domain Glyco_trans_2_3 PF13632.6 EWM26723.1 - 8.6e-24 84.5 4.4 8.6e-24 84.5 4.4 3.6 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EWM26723.1 - 8e-06 25.9 0.0 1.4e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 CCDC24 PF15669.5 EWM26723.1 - 0.35 10.7 0.3 0.56 10.0 0.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family EST1_DNA_bind PF10373.9 EWM26724.1 - 4.8e-36 124.7 0.0 5.2e-35 121.3 0.0 2.1 1 1 1 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.9 EWM26724.1 - 2.1e-11 44.6 1.2 1.2e-08 35.7 1.2 2.7 1 1 0 1 1 1 1 Telomerase activating protein Est1 TPR_12 PF13424.6 EWM26724.1 - 0.058 13.7 1.5 5.2 7.4 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Branch PF02485.21 EWM26725.1 - 1.3e-12 47.8 0.0 3.6e-12 46.3 0.0 1.6 2 0 0 2 2 2 1 Core-2/I-Branching enzyme SCO1-SenC PF02630.14 EWM26726.1 - 1.1e-25 90.1 0.0 1.6e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.6 EWM26726.1 - 0.089 13.1 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like NAD_binding_1 PF00175.21 EWM26726.1 - 0.16 12.6 0.0 0.33 11.6 0.0 1.7 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain TPR_2 PF07719.17 EWM26728.1 - 5.7e-05 22.9 4.6 0.0017 18.3 1.3 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EWM26728.1 - 0.019 14.7 3.9 1.1 9.2 1.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_2 PF13041.6 EWM26729.1 - 2.3e-55 184.6 2.3 5.4e-07 29.7 0.0 13.4 8 5 6 14 14 14 13 PPR repeat family PPR_3 PF13812.6 EWM26729.1 - 1e-43 147.2 0.0 2.3e-10 40.4 0.0 10.5 7 2 5 12 12 12 8 Pentatricopeptide repeat domain PPR PF01535.20 EWM26729.1 - 9.7e-39 128.9 24.8 8e-05 22.6 0.0 16.3 17 1 0 17 17 17 10 PPR repeat PPR_1 PF12854.7 EWM26729.1 - 7.4e-28 96.0 6.0 0.004 16.8 0.0 12.5 12 0 0 12 12 12 7 PPR repeat PPR_long PF17177.4 EWM26729.1 - 6.6e-22 77.9 7.1 1.1e-06 28.1 0.1 6.4 2 1 4 6 6 6 5 Pentacotripeptide-repeat region of PRORP ANAPC3 PF12895.7 EWM26729.1 - 5.1e-05 23.4 1.6 7.1 6.9 0.0 5.3 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 PPR_2 PF13041.6 EWM26730.1 - 2.7e-55 184.4 2.3 5.5e-07 29.7 0.0 13.4 8 5 6 14 14 14 12 PPR repeat family PPR_3 PF13812.6 EWM26730.1 - 1.2e-43 147.0 0.0 2.4e-10 40.4 0.0 10.5 7 2 5 12 12 12 8 Pentatricopeptide repeat domain PPR PF01535.20 EWM26730.1 - 1.2e-38 128.7 24.8 8.2e-05 22.6 0.0 16.2 17 1 0 17 17 17 10 PPR repeat PPR_1 PF12854.7 EWM26730.1 - 8.6e-28 95.7 6.0 0.004 16.8 0.0 12.5 12 0 0 12 12 12 7 PPR repeat PPR_long PF17177.4 EWM26730.1 - 7e-22 77.8 7.1 1.2e-06 28.1 0.1 6.3 2 1 4 6 6 6 6 Pentacotripeptide-repeat region of PRORP ANAPC3 PF12895.7 EWM26730.1 - 5.5e-05 23.3 1.6 7.2 6.9 0.0 5.3 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 FAD_binding_2 PF00890.24 EWM26732.1 - 3.1e-72 244.0 5.6 4.8e-72 243.3 5.6 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EWM26732.1 - 1.1e-08 34.7 0.1 0.00012 21.4 0.1 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EWM26732.1 - 5.1e-07 29.6 0.2 5.1e-07 29.6 0.2 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase Succ_DH_flav_C PF02910.20 EWM26732.1 - 3.2e-06 27.2 1.8 6e-06 26.3 1.8 1.5 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.22 EWM26732.1 - 4.1e-05 22.8 2.6 0.00021 20.5 0.1 2.8 3 0 0 3 3 3 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EWM26732.1 - 0.00023 20.3 0.2 0.00045 19.4 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 EWM26732.1 - 0.006 16.0 1.0 0.006 16.0 1.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EWM26732.1 - 0.014 14.6 0.8 0.12 11.6 0.2 2.7 2 1 1 3 3 3 0 Thi4 family FAD_binding_3 PF01494.19 EWM26732.1 - 0.019 14.3 0.1 0.034 13.4 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain PE PF00934.20 EWM26732.1 - 0.023 15.0 2.3 1.1 9.7 0.1 3.1 2 1 0 2 2 2 0 PE family AlaDh_PNT_C PF01262.21 EWM26732.1 - 0.15 11.3 0.5 0.51 9.6 0.5 1.9 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 EWM26732.1 - 0.38 9.4 2.0 0.43 9.2 0.1 2.0 3 0 0 3 3 3 0 HI0933-like protein ABC1 PF03109.16 EWM26733.1 - 2.6e-33 114.7 0.0 6.5e-33 113.4 0.0 1.7 2 0 0 2 2 2 1 ABC1 family Pkinase PF00069.25 EWM26733.1 - 0.091 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain FAD_binding_6 PF00970.24 EWM26734.1 - 5.1e-05 23.5 0.0 9.3e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EWM26734.1 - 0.035 14.7 0.0 0.077 13.6 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain TFIIA PF03153.13 EWM26735.1 - 0.23 11.4 7.4 0.34 10.9 7.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TFIIA PF03153.13 EWM26736.1 - 0.23 11.4 7.4 0.33 10.9 7.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF629 PF04780.12 EWM26736.1 - 0.29 9.6 0.5 0.41 9.1 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) PAD_porph PF04371.15 EWM26737.1 - 8e-96 321.1 0.0 9.4e-96 320.8 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Pkinase_Tyr PF07714.17 EWM26738.1 - 4.1e-47 160.6 0.0 5.9e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EWM26738.1 - 1.8e-44 152.1 0.0 2.6e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EWM26738.1 - 5.1e-06 26.6 0.0 0.00046 20.2 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family PIP49_C PF12260.8 EWM26738.1 - 0.0066 16.1 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 GCP_C_terminal PF04130.13 EWM26739.1 - 1.2e-68 231.9 1.8 1.8e-68 231.3 1.8 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EWM26739.1 - 1.9e-64 218.2 0.0 9.3e-64 216.0 0.0 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal Myb_DNA-binding PF00249.31 EWM26740.1 - 2.5e-08 34.0 0.1 4.4e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain CgtA PF06306.11 EWM26740.1 - 0.16 11.3 0.0 0.22 10.9 0.0 1.1 1 0 0 1 1 1 0 Beta-1,4-N-acetylgalactosaminyltransferase (CgtA) DUF2381 PF09544.10 EWM26741.1 - 0.13 11.7 1.0 0.16 11.4 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) zf-C3HC4_3 PF13920.6 EWM26742.1 - 1.1e-08 34.8 3.7 1.7e-08 34.2 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EWM26742.1 - 1.1e-06 28.8 5.3 2.2e-06 27.9 5.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 EWM26742.1 - 2.2e-06 27.7 4.9 4e-06 26.9 4.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 EWM26742.1 - 2.8e-06 27.1 3.4 4.7e-06 26.4 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EWM26742.1 - 7.3e-06 25.7 4.4 1.3e-05 24.9 4.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EWM26742.1 - 0.0016 18.6 3.0 0.0057 16.9 3.0 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EWM26742.1 - 0.0065 16.5 4.8 0.014 15.4 4.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EWM26742.1 - 0.0076 16.1 5.4 0.013 15.3 5.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EWM26742.1 - 0.0091 15.9 4.8 0.017 15.1 4.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain DZR PF12773.7 EWM26742.1 - 0.13 12.3 2.0 0.33 11.0 2.0 1.7 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_6 PF14835.6 EWM26742.1 - 0.13 12.1 1.8 0.26 11.2 1.8 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 EWM26742.1 - 0.17 11.7 2.9 0.44 10.4 2.9 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.11 EWM26742.1 - 0.4 10.8 2.6 1 9.5 2.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DUF2685 PF10886.8 EWM26742.1 - 0.55 10.5 3.0 0.53 10.5 1.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2685) DUF3727 PF12527.8 EWM26743.1 - 5.5e-06 26.5 0.0 0.0013 18.9 0.0 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF3727) PAP2_3 PF14378.6 EWM26743.1 - 0.12 12.1 0.3 0.18 11.5 0.3 1.3 1 0 0 1 1 1 0 PAP2 superfamily CUE PF02845.16 EWM26745.1 - 0.022 14.5 0.0 0.062 13.0 0.0 1.9 1 0 0 1 1 1 0 CUE domain S1 PF00575.23 EWM26746.1 - 4.4e-10 39.8 1.6 2e-09 37.7 1.7 2.1 2 0 0 2 2 2 1 S1 RNA binding domain AMP-binding PF00501.28 EWM26747.1 - 7e-43 146.8 0.0 1e-42 146.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PQQ_3 PF13570.6 EWM26747.1 - 4.4e-17 62.0 0.1 0.00069 20.0 0.0 5.9 6 0 0 6 6 6 4 PQQ-like domain PQQ_2 PF13360.6 EWM26747.1 - 6.7e-17 61.9 0.0 3.4e-11 43.2 0.0 2.5 1 1 1 2 2 2 2 PQQ-like domain PQQ PF01011.21 EWM26747.1 - 8e-16 57.1 0.0 7.2e-05 22.5 0.0 5.1 6 0 0 6 6 6 3 PQQ enzyme repeat AMP-binding PF00501.28 EWM26748.1 - 4.6e-20 71.6 0.0 6.6e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PQQ_3 PF13570.6 EWM26748.1 - 9.3e-18 64.1 0.1 0.0005 20.5 0.0 6.0 6 0 0 6 6 6 4 PQQ-like domain PQQ_2 PF13360.6 EWM26748.1 - 2.9e-17 63.1 0.0 2e-11 43.9 0.0 2.6 1 1 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 EWM26748.1 - 1.9e-16 59.1 0.0 5.2e-05 23.0 0.0 5.3 6 0 0 6 6 6 3 PQQ enzyme repeat AMP-binding PF00501.28 EWM26749.1 - 7e-43 146.8 0.0 1e-42 146.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PQQ_3 PF13570.6 EWM26749.1 - 4.4e-17 62.0 0.1 0.00069 20.0 0.0 5.9 6 0 0 6 6 6 4 PQQ-like domain PQQ_2 PF13360.6 EWM26749.1 - 6.7e-17 61.9 0.0 3.4e-11 43.2 0.0 2.5 1 1 1 2 2 2 2 PQQ-like domain PQQ PF01011.21 EWM26749.1 - 8e-16 57.1 0.0 7.2e-05 22.5 0.0 5.1 6 0 0 6 6 6 3 PQQ enzyme repeat tRNA-synt_2c PF01411.19 EWM26750.1 - 4e-201 669.3 0.0 5e-201 669.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EWM26750.1 - 1.2e-14 54.1 0.0 2.7e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 EWM26750.1 - 2.9e-05 24.5 1.3 9.3e-05 22.9 0.8 2.2 1 1 1 2 2 2 1 DHHA1 domain Leu_zip PF15294.6 EWM26751.1 - 0.033 13.7 12.2 0.061 12.8 12.2 1.4 1 0 0 1 1 1 0 Leucine zipper TSC22 PF01166.18 EWM26751.1 - 0.064 13.6 0.3 0.064 13.6 0.3 3.0 3 0 0 3 3 3 0 TSC-22/dip/bun family YabA PF06156.13 EWM26751.1 - 0.21 12.3 13.1 0.17 12.6 1.5 3.1 2 1 1 3 3 3 0 Initiation control protein YabA WDCP PF15390.6 EWM26751.1 - 1.3 7.3 6.5 1.8 6.9 6.5 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family CRAL_TRIO PF00650.20 EWM26753.1 - 1.4e-26 93.2 0.0 1.8e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain Copine PF07002.16 EWM26754.1 - 1.3e-38 132.7 0.0 5.6e-37 127.3 0.0 2.1 1 1 0 1 1 1 1 Copine DMA PF03474.14 EWM26754.1 - 0.043 13.4 0.0 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 DMRTA motif zf-C2H2_2 PF12756.7 EWM26755.1 - 7.2e-30 103.3 16.2 5.8e-24 84.3 3.5 3.3 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EWM26755.1 - 2.1e-09 37.4 23.1 4.1e-07 30.1 1.9 4.2 4 1 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EWM26755.1 - 2.7e-09 37.1 17.0 8.8e-08 32.3 3.3 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EWM26755.1 - 5.6e-07 29.9 19.2 0.0019 18.9 0.5 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.26 EWM26755.1 - 0.0083 16.5 1.5 0.0083 16.5 1.5 4.0 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 EWM26755.1 - 0.0087 15.8 5.2 0.42 10.4 0.4 2.9 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 EWM26755.1 - 0.026 14.4 5.3 0.27 11.2 0.1 3.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 EWM26755.1 - 0.075 13.1 6.9 0.61 10.2 1.5 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger HNH PF01844.23 EWM26755.1 - 0.14 12.3 5.8 5.6 7.2 0.1 3.6 3 0 0 3 3 3 0 HNH endonuclease DUF629 PF04780.12 EWM26755.1 - 0.45 9.0 6.2 7.8 4.9 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF629) OrsD PF12013.8 EWM26755.1 - 2.8 8.4 5.9 2.1 8.8 0.4 2.8 3 0 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D Rft-1 PF04506.13 EWM26756.1 - 3.2e-109 366.0 0.0 4.4e-109 365.5 0.0 1.2 1 0 0 1 1 1 1 Rft protein Polysacc_synt_C PF14667.6 EWM26756.1 - 1.9e-05 24.7 4.9 1.9e-05 24.7 4.9 4.1 4 0 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain DUF2101 PF09874.9 EWM26756.1 - 6.6 6.4 8.3 2.1 8.0 0.4 2.9 2 1 1 3 3 3 0 Predicted membrane protein (DUF2101) Pkinase PF00069.25 EWM26758.1 - 2.9e-68 230.1 0.0 3.7e-68 229.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM26758.1 - 5.3e-31 107.8 0.0 8.1e-31 107.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EWM26758.1 - 0.009 15.4 0.7 0.027 13.8 0.6 1.9 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EWM26758.1 - 0.025 13.5 0.1 0.036 13.0 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 EWM26758.1 - 0.082 12.5 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.11 EWM26758.1 - 0.1 11.5 0.8 0.14 11.1 0.3 1.4 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase APH PF01636.23 EWM26758.1 - 0.14 12.1 0.4 0.38 10.6 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EWM26758.1 - 0.21 10.9 0.0 0.39 10.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like RAMP4 PF06624.12 EWM26759.1 - 1.1e-24 86.3 0.4 1.4e-24 85.9 0.4 1.2 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 HSP20 PF00011.21 EWM26760.1 - 1.2e-21 76.8 1.7 1.5e-21 76.4 1.7 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EWM26760.1 - 2.4e-09 36.6 0.0 3.7e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Frataxin_Cyay PF01491.16 EWM26760.1 - 0.0065 16.5 0.1 0.4 10.8 0.0 2.2 2 0 0 2 2 2 1 Frataxin-like domain FKBP26_C PF18046.1 EWM26760.1 - 0.0075 16.3 0.4 0.29 11.2 0.1 2.2 2 0 0 2 2 2 1 FKBP26_C-terminal ATP13 PF12921.7 EWM26761.1 - 0.0033 17.3 0.0 0.015 15.2 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial ATPase expression PPR PF01535.20 EWM26761.1 - 0.016 15.4 1.0 8.7 6.8 0.0 4.6 5 0 0 5 5 5 0 PPR repeat Tim17 PF02466.19 EWM26762.1 - 1.1e-26 93.3 7.5 1.4e-26 93.0 7.5 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.9 EWM26762.1 - 0.084 13.0 1.1 0.084 13.0 1.1 2.2 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide ECH_1 PF00378.20 EWM26763.1 - 5.3e-22 78.4 0.0 6.8e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EWM26763.1 - 1.8e-17 63.8 0.0 2.4e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase NDK PF00334.19 EWM26764.1 - 2.9e-52 176.3 0.0 6.4e-52 175.1 0.0 1.5 2 0 0 2 2 2 1 Nucleoside diphosphate kinase DUF3168 PF11367.8 EWM26765.1 - 0.009 16.2 0.1 0.013 15.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3168) CHAD PF05235.14 EWM26765.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 CHAD domain MM_CoA_mutase PF01642.22 EWM26766.1 - 1.8e-235 782.3 0.3 2.2e-235 782.0 0.3 1.1 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 EWM26766.1 - 2.8e-15 56.4 0.5 6.5e-15 55.2 0.5 1.7 1 0 0 1 1 1 1 B12 binding domain NPR2 PF06218.11 EWM26767.1 - 7.8e-77 258.9 0.0 8.2e-75 252.2 0.0 2.2 1 1 0 1 1 1 1 Nitrogen permease regulator 2 PAS_9 PF13426.7 EWM26768.1 - 1.3e-18 67.1 0.0 4.5e-18 65.4 0.0 1.8 2 0 0 2 2 2 1 PAS domain bZIP_2 PF07716.15 EWM26768.1 - 7.4e-08 32.3 11.4 1.3e-07 31.6 11.4 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EWM26768.1 - 2.7e-07 30.6 8.6 4.6e-07 29.8 8.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor PAS_3 PF08447.12 EWM26768.1 - 9.2e-07 29.1 0.0 1.9e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 EWM26768.1 - 0.0004 20.4 0.0 0.0009 19.2 0.0 1.5 1 0 0 1 1 1 1 PAS fold HAP1_N PF04849.13 EWM26768.1 - 0.0016 17.7 2.9 0.0022 17.2 2.9 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region PAS_4 PF08448.10 EWM26768.1 - 0.017 15.4 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 PAS fold GIT_CC PF16559.5 EWM26768.1 - 0.022 14.6 0.1 0.054 13.4 0.1 1.7 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_Maf PF03131.17 EWM26768.1 - 0.024 15.1 5.3 0.046 14.3 5.3 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor TolA_bind_tri PF16331.5 EWM26768.1 - 0.044 13.9 0.5 0.11 12.6 0.5 1.7 1 0 0 1 1 1 0 TolA binding protein trimerisation HSP70 PF00012.20 EWM26769.1 - 1.5e-264 878.8 8.5 1.7e-264 878.6 8.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EWM26769.1 - 4.5e-15 55.3 5.5 8.2e-14 51.2 0.2 3.0 3 0 0 3 3 3 2 MreB/Mbl protein FtsA PF14450.6 EWM26769.1 - 0.0027 18.1 2.5 2.5 8.5 0.0 3.5 3 1 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 EWM26769.1 - 0.0067 16.2 0.0 0.017 14.8 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain GFRP PF06399.13 EWM26769.1 - 0.0067 16.3 0.0 0.019 14.8 0.0 1.7 1 0 0 1 1 1 1 GTP cyclohydrolase I feedback regulatory protein (GFRP) VSG_B PF13206.6 EWM26769.1 - 0.014 14.6 8.2 0.025 13.9 8.2 1.3 1 0 0 1 1 1 0 Trypanosomal VSG domain PPDK_N PF01326.19 EWM26769.1 - 0.02 14.2 1.8 0.033 13.5 1.8 1.3 1 0 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain RNA_pol_Rpb1_6 PF04992.14 EWM26769.1 - 0.066 13.0 0.5 0.19 11.5 0.5 1.8 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 Dynamin_M PF01031.20 EWM26769.1 - 0.23 10.6 2.2 1.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Dynamin central region Anti-adapt_IraP PF10796.9 EWM26769.1 - 0.81 10.3 6.9 1.5 9.4 5.4 2.3 2 0 0 2 2 2 0 Sigma-S stabilisation anti-adaptor protein ATP-synt_B PF00430.18 EWM26769.1 - 1.1 9.3 19.2 0.19 11.8 14.7 2.0 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) TFIIA PF03153.13 EWM26770.1 - 0.0094 16.0 6.8 0.021 14.8 6.8 1.5 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Med3 PF11593.8 EWM26770.1 - 0.92 8.6 12.0 1.5 7.9 12.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Spt20 PF12090.8 EWM26770.1 - 4.3 6.9 18.0 7.2 6.1 18.0 1.2 1 0 0 1 1 1 0 Spt20 family Mer2 PF09074.10 EWM26771.1 - 0.016 15.0 1.1 0.016 15.0 1.1 2.2 2 1 1 3 3 3 0 Mer2 DUF2120 PF09893.9 EWM26771.1 - 0.12 12.5 0.5 5.7 7.0 0.2 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) Spore_III_AB PF09548.10 EWM26771.1 - 0.78 9.8 5.2 0.77 9.8 0.3 2.3 1 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) PI3_PI4_kinase PF00454.27 EWM26772.1 - 1.6e-26 93.7 0.0 6.9e-21 75.2 0.0 2.3 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PH PF00169.29 EWM26772.1 - 4.3e-11 43.2 0.0 9.2e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EWM26772.1 - 0.00032 21.1 3.2 0.0046 17.4 3.2 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 EWM26772.1 - 0.0026 18.0 0.0 0.0078 16.5 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 EWM26772.1 - 0.024 15.0 0.2 0.18 12.2 0.2 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain Adeno_VII PF03228.14 EWM26772.1 - 0.079 13.6 0.2 5.1 7.8 0.0 2.9 3 0 0 3 3 3 0 Adenoviral core protein VII Bclx_interact PF08945.10 EWM26772.1 - 0.16 11.8 0.4 0.4 10.5 0.4 1.7 1 0 0 1 1 1 0 Bcl-x interacting, BH3 domain Trefoil PF00088.18 EWM26772.1 - 1.3 9.0 3.6 1.1 9.2 0.1 2.4 2 0 0 2 2 2 0 Trefoil (P-type) domain DUF2518 PF10726.9 EWM26773.1 - 0.1 12.3 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of function (DUF2518) DUF5379 PF17350.2 EWM26773.1 - 0.11 12.7 0.1 0.17 12.2 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5379) Kinesin PF00225.23 EWM26774.1 - 1e-109 366.5 0.2 2.5e-109 365.2 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EWM26774.1 - 1.4e-43 148.4 0.0 3.3e-43 147.2 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding Polysacc_deac_1 PF01522.21 EWM26774.1 - 0.018 14.9 0.3 0.054 13.4 0.3 1.8 1 0 0 1 1 1 0 Polysaccharide deacetylase LCM PF04072.14 EWM26775.1 - 4.1e-34 118.2 0.0 9e-34 117.1 0.0 1.5 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase COG5 PF10392.9 EWM26776.1 - 4e-13 49.7 2.2 5.9e-13 49.1 0.4 2.2 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Vps54_N PF10475.9 EWM26776.1 - 0.0037 16.6 2.3 0.0068 15.7 2.3 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 EWM26776.1 - 0.6 8.6 3.7 0.96 7.9 3.7 1.2 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 HisKA PF00512.25 EWM26776.1 - 0.7 10.0 3.4 2.2 8.4 0.4 3.4 2 1 1 3 3 3 0 His Kinase A (phospho-acceptor) domain HEAT_2 PF13646.6 EWM26777.1 - 4.2e-42 142.4 10.5 2.6e-14 53.4 0.4 3.9 2 2 2 4 4 4 4 HEAT repeats HEAT_PBS PF03130.16 EWM26777.1 - 1.2e-23 81.3 8.1 0.0003 21.2 0.0 6.5 7 0 0 7 7 7 5 PBS lyase HEAT-like repeat HEAT PF02985.22 EWM26777.1 - 7.9e-10 38.1 1.0 0.044 14.1 0.0 5.7 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 EWM26777.1 - 1e-05 25.9 5.6 0.52 10.9 0.3 4.9 4 2 0 4 4 4 3 HEAT-like repeat Cnd1 PF12717.7 EWM26777.1 - 0.013 15.5 0.0 8.1 6.5 0.0 3.8 3 1 2 5 5 5 0 non-SMC mitotic condensation complex subunit 1 T2SSK PF03934.13 EWM26777.1 - 0.018 14.4 0.2 0.048 13.0 0.1 1.7 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein K PUB_1 PF18486.1 EWM26777.1 - 0.073 12.9 0.0 0.26 11.2 0.0 1.9 1 0 0 1 1 1 0 PNGase/UBA- or UBX-containing domain Arm PF00514.23 EWM26777.1 - 0.074 13.1 0.0 8.9 6.5 0.0 3.2 2 1 0 2 2 2 0 Armadillo/beta-catenin-like repeat tRNA-synt_1c PF00749.21 EWM26778.1 - 1.1e-98 330.1 0.1 1.7e-98 329.4 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EWM26778.1 - 2.4e-36 125.2 0.0 4.1e-36 124.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain WHEP-TRS PF00458.20 EWM26778.1 - 2.8e-09 37.0 0.2 7.5e-09 35.6 0.2 1.8 1 0 0 1 1 1 1 WHEP-TRS domain GST_C PF00043.25 EWM26778.1 - 8.6e-07 29.1 0.0 5.7e-06 26.5 0.0 2.4 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EWM26778.1 - 1.8e-05 24.8 0.1 0.00058 20.0 0.0 2.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EWM26778.1 - 0.00083 19.3 0.2 0.002 18.1 0.2 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 EWM26778.1 - 0.13 11.6 4.4 0.076 12.3 0.2 2.3 2 1 1 3 3 3 0 tRNA synthetases class I (C) catalytic domain Hydrolase_6 PF13344.6 EWM26779.1 - 1e-19 70.5 0.0 3.7e-19 68.7 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EWM26779.1 - 3.5e-14 52.6 0.1 4.3e-13 49.1 0.0 2.3 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 EWM26779.1 - 0.14 12.4 0.0 15 5.8 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase UCH PF00443.29 EWM26780.1 - 9.1e-17 61.4 0.0 1.1e-16 61.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EWM26780.1 - 0.00044 19.9 0.0 0.0005 19.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RabGAP-TBC PF00566.18 EWM26781.1 - 6.1e-52 176.4 0.0 1.6e-27 96.6 0.1 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Ribosomal_L19 PF01245.20 EWM26783.1 - 3.5e-17 62.3 0.0 4.8e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L19 UQ_con PF00179.26 EWM26784.1 - 3.8e-26 91.4 0.0 5.3e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EWM26784.1 - 1.4e-05 24.8 0.0 2.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UFC1 PF08694.11 EWM26784.1 - 0.056 13.1 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 UEV PF05743.13 EWM26784.1 - 0.058 13.2 0.0 0.096 12.6 0.0 1.4 1 0 0 1 1 1 0 UEV domain RWD PF05773.22 EWM26784.1 - 0.1 12.9 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 RWD domain ATG11 PF10377.9 EWM26785.1 - 2.2e-20 73.1 0.0 6.1e-20 71.6 0.0 1.7 2 0 0 2 2 2 1 Autophagy-related protein 11 APG17 PF04108.12 EWM26785.1 - 1.8e-05 24.0 0.5 1.8e-05 24.0 0.5 3.3 3 1 0 4 4 4 1 Autophagy protein Apg17 Mto2_bdg PF12808.7 EWM26785.1 - 0.45 10.8 7.3 3.4 8.0 0.3 3.7 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Mod_r PF07200.13 EWM26785.1 - 6.5 6.9 6.3 3.5 7.7 0.7 3.0 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Glyco_tran_28_C PF04101.16 EWM26786.1 - 2.5e-23 82.9 0.1 7.3e-21 74.9 0.1 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain CBM49 PF09478.10 EWM26787.1 - 0.00019 21.7 0.1 4.2 7.8 0.0 5.0 5 1 0 5 5 5 2 Carbohydrate binding domain CBM49 TPR_2 PF07719.17 EWM26788.1 - 1e-10 40.9 3.0 0.017 15.2 0.7 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EWM26788.1 - 2.7e-09 36.4 2.5 0.0067 16.2 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat FKBP_C PF00254.28 EWM26788.1 - 1.2e-08 35.1 0.0 2.3e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_16 PF13432.6 EWM26788.1 - 1.5e-06 28.7 1.4 0.00031 21.3 0.5 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EWM26788.1 - 0.0017 19.0 3.0 6.4 7.9 1.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EWM26788.1 - 0.0018 18.4 1.1 5.6 7.4 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EWM26788.1 - 0.0064 16.4 0.1 3.3 7.9 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EWM26788.1 - 0.011 16.2 5.9 0.05 14.1 1.9 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EWM26788.1 - 0.017 15.4 1.6 0.12 12.7 0.3 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 EWM26788.1 - 0.054 13.9 0.1 13 6.5 0.0 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 EWM26788.1 - 0.06 13.0 1.2 13 5.6 0.0 3.2 3 0 0 3 3 3 0 TPR repeat DUF3449 PF11931.8 EWM26788.1 - 0.11 12.3 3.4 0.22 11.3 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Bromodomain PF00439.25 EWM26789.1 - 4.7e-24 84.3 0.0 3.8e-13 49.3 0.0 3.3 2 1 0 2 2 2 2 Bromodomain DNMT1-RFD PF12047.8 EWM26789.1 - 1.8e-09 37.8 0.0 9.6e-07 28.9 0.0 2.6 2 0 0 2 2 2 2 Cytosine specific DNA methyltransferase replication foci domain WSD PF15613.6 EWM26789.1 - 9.8e-08 32.4 0.6 3.9e-06 27.3 0.6 2.7 1 1 0 1 1 1 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif WHIM1 PF15612.6 EWM26789.1 - 0.0002 20.8 0.0 0.00044 19.7 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Auxin_resp PF06507.13 EWM26789.1 - 0.0031 17.7 0.0 0.0074 16.5 0.0 1.6 1 0 0 1 1 1 1 Auxin response factor Bromodomain PF00439.25 EWM26790.1 - 4.7e-24 84.3 0.0 3.8e-13 49.3 0.0 3.3 2 1 0 2 2 2 2 Bromodomain DNMT1-RFD PF12047.8 EWM26790.1 - 1.8e-09 37.8 0.0 9.6e-07 28.9 0.0 2.6 2 0 0 2 2 2 2 Cytosine specific DNA methyltransferase replication foci domain WSD PF15613.6 EWM26790.1 - 9.8e-08 32.4 0.6 3.9e-06 27.3 0.6 2.7 1 1 0 1 1 1 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif WHIM1 PF15612.6 EWM26790.1 - 0.0002 20.8 0.0 0.00044 19.7 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Auxin_resp PF06507.13 EWM26790.1 - 0.0031 17.7 0.0 0.0074 16.5 0.0 1.6 1 0 0 1 1 1 1 Auxin response factor Yip1 PF04893.17 EWM26791.1 - 2.6e-10 40.3 10.9 3.9e-10 39.7 10.9 1.3 1 0 0 1 1 1 1 Yip1 domain Rib_5-P_isom_A PF06026.14 EWM26792.1 - 1.5e-42 145.2 0.1 2.1e-42 144.7 0.1 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Sugar-bind PF04198.13 EWM26792.1 - 0.064 12.4 0.0 0.098 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain Rib_5-P_isom_A PF06026.14 EWM26793.1 - 1.2e-42 145.4 0.1 1.5e-42 145.1 0.1 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Lectin_C PF00059.21 EWM26794.1 - 1.5e-08 35.3 0.0 8.6e-08 32.9 0.0 2.3 2 0 0 2 2 2 1 Lectin C-type domain WSC PF01822.19 EWM26794.1 - 2.3e-06 27.7 10.0 2.3e-06 27.7 10.0 2.7 3 0 0 3 3 3 1 WSC domain Fascin PF06268.13 EWM26794.1 - 0.039 14.2 0.0 0.13 12.5 0.0 1.9 1 0 0 1 1 1 0 Fascin domain SH2 PF00017.24 EWM26795.1 - 5.7e-05 23.1 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 SH2 domain tRNA-synt_1c PF00749.21 EWM26798.1 - 2e-99 332.4 0.0 2.5e-99 332.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain TMEM252 PF15664.5 EWM26798.1 - 0.2 11.4 0.1 0.77 9.5 0.1 1.9 2 0 0 2 2 2 0 Transmembrane protein 252 family Dynein_light PF01221.18 EWM26799.1 - 5.9e-42 141.9 1.2 8.8e-42 141.3 1.2 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 GCV_H PF01597.19 EWM26801.1 - 2.9e-10 40.1 0.0 4.3e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage H-protein Arf PF00025.21 EWM26802.1 - 1.4e-78 262.3 0.1 1.6e-78 262.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EWM26802.1 - 1.1e-14 54.6 0.0 1.6e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EWM26802.1 - 7.9e-13 48.3 0.0 8.9e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EWM26802.1 - 1.2e-12 47.6 0.0 1.5e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EWM26802.1 - 3.8e-12 46.0 0.6 5.1e-08 32.5 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EWM26802.1 - 1.7e-09 37.4 0.0 2e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EWM26802.1 - 1.8e-05 24.8 0.0 2.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EWM26802.1 - 0.0083 15.5 0.1 0.011 15.1 0.1 1.3 1 1 0 1 1 1 1 6-phosphofructo-2-kinase Complex1_LYR PF05347.15 EWM26803.1 - 8.1e-13 48.2 0.2 1.4e-12 47.5 0.2 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 EWM26803.1 - 0.00019 22.0 0.0 0.00027 21.5 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.6 EWM26803.1 - 0.00096 19.9 0.7 0.0017 19.0 0.7 1.4 1 1 0 1 1 1 1 Complex1_LYR-like AdoHcyase PF05221.17 EWM26806.1 - 0.29 10.3 0.0 0.32 10.1 0.0 1.1 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase Band_7 PF01145.25 EWM26807.1 - 7e-21 75.0 0.9 9.8e-21 74.6 0.9 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.8 EWM26807.1 - 0.02 15.0 0.9 0.033 14.3 0.9 1.4 1 0 0 1 1 1 0 Mediator complex subunit 2 ThiF PF00899.21 EWM26809.1 - 1.3e-42 145.9 0.0 1.9e-42 145.3 0.0 1.2 1 0 0 1 1 1 1 ThiF family ATG7_N PF16420.5 EWM26809.1 - 1.3e-19 71.0 0.0 1.8e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus Shikimate_DH PF01488.20 EWM26809.1 - 0.17 12.0 0.0 0.84 9.7 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Paf1 PF03985.13 EWM26809.1 - 4.3 6.2 5.9 6.1 5.7 5.9 1.1 1 0 0 1 1 1 0 Paf1 GTP_EFTU PF00009.27 EWM26810.1 - 2.2e-62 210.0 0.0 3.5e-62 209.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 EWM26810.1 - 3.7e-26 91.0 0.0 1.6e-25 89.0 0.0 2.2 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.24 EWM26810.1 - 4e-21 74.8 0.0 8.2e-21 73.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 EWM26810.1 - 3.4e-06 26.8 0.0 1.4e-05 24.8 0.0 2.1 1 1 1 2 2 2 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 EWM26810.1 - 1.5e-05 25.3 0.1 5.6e-05 23.5 0.1 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EWM26810.1 - 4.5e-05 23.5 0.1 9.3e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RF3_C PF16658.5 EWM26810.1 - 0.0011 18.7 0.1 0.0023 17.7 0.1 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain AIG1 PF04548.16 EWM26810.1 - 0.051 12.9 0.0 0.086 12.1 0.0 1.2 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.18 EWM26810.1 - 0.17 11.4 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B DUF3138 PF11336.8 EWM26810.1 - 0.49 8.9 1.9 0.87 8.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Chloroa_b-bind PF00504.21 EWM26813.1 - 4.2e-40 137.9 0.0 5.5e-40 137.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Trypsin PF00089.26 EWM26814.1 - 1.3e-10 41.4 0.1 1.6e-09 38.0 0.1 2.1 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 EWM26814.1 - 7.2e-10 39.9 0.0 1.2e-09 39.2 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain WLM PF08325.10 EWM26815.1 - 1.5e-34 119.7 0.0 3.2e-34 118.7 0.0 1.6 1 1 0 1 1 1 1 WLM domain PUB PF09409.10 EWM26815.1 - 1.2e-13 50.8 0.0 2.8e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 PUB domain UBA PF00627.31 EWM26815.1 - 2.4e-05 24.1 0.8 6.3e-05 22.8 0.4 2.0 2 0 0 2 2 2 1 UBA/TS-N domain ubiquitin PF00240.23 EWM26815.1 - 0.00042 20.0 0.1 0.00093 18.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family WIYLD PF10440.9 EWM26815.1 - 0.0063 16.3 0.0 5.4 6.9 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin-binding WIYLD domain DUF45 PF01863.17 EWM26815.1 - 0.11 12.5 1.2 0.24 11.4 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF45 ABC1 PF03109.16 EWM26816.1 - 3.6e-24 85.2 0.0 7.3e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 EWM26816.1 - 4.7e-05 23.1 0.0 0.00016 21.3 0.0 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 EWM26816.1 - 5.4e-05 23.2 1.6 0.00043 20.3 0.2 2.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 EWM26816.1 - 0.0091 15.4 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM26816.1 - 0.12 11.7 0.0 0.34 10.1 0.0 1.7 2 0 0 2 2 2 0 Protein tyrosine kinase GPI-anchored PF10342.9 EWM26817.1 - 0.0041 17.8 1.4 0.006 17.3 0.1 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family FtsJ PF01728.19 EWM26818.1 - 2.3e-46 158.1 0.0 2.8e-46 157.8 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase FtsJ PF01728.19 EWM26819.1 - 5.1e-38 130.9 0.0 6.3e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Thioredoxin_8 PF13905.6 EWM26820.1 - 2.2e-23 82.4 0.0 2.9e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 EWM26820.1 - 2.3e-09 37.1 0.0 3.4e-09 36.5 0.0 1.3 1 1 0 1 1 1 1 Redoxin Thioredoxin PF00085.20 EWM26820.1 - 1.4e-08 34.7 0.0 7.9e-07 29.0 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin AhpC-TSA PF00578.21 EWM26820.1 - 4.4e-07 29.8 0.0 7.3e-07 29.1 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 EWM26820.1 - 1.4e-05 25.2 0.0 0.00028 21.0 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EWM26820.1 - 1.8e-05 25.1 0.0 3.6e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 EWM26820.1 - 0.012 15.5 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 EWM26820.1 - 0.017 14.9 0.0 0.041 13.6 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin DUF953 PF06110.11 EWM26820.1 - 0.066 12.8 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Glutaredoxin PF00462.24 EWM26820.1 - 0.11 12.7 0.1 0.25 11.6 0.0 1.7 1 1 1 2 2 2 0 Glutaredoxin DUF5436 PF17504.2 EWM26821.1 - 0.13 12.6 0.1 0.31 11.4 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5436) Bromodomain PF00439.25 EWM26822.1 - 4.1e-17 62.0 0.0 8e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 EWM26822.1 - 1.4e-11 44.7 0.3 3.3e-11 43.5 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EWM26822.1 - 1.1e-07 31.8 0.1 3.6e-07 30.2 0.1 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EWM26822.1 - 5.7e-05 23.5 0.6 0.00012 22.4 0.6 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MSA-2c PF12238.8 EWM26822.1 - 0.042 13.9 2.1 0.68 9.9 0.7 2.2 2 0 0 2 2 2 0 Merozoite surface antigen 2c COX7a PF02238.15 EWM26823.1 - 0.028 14.8 0.2 0.18 12.2 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VII FlxA PF14282.6 EWM26823.1 - 1.1 9.3 14.5 1 9.4 1.1 2.4 2 0 0 2 2 2 0 FlxA-like protein DAGAT PF03982.13 EWM26824.1 - 2.9e-42 144.6 0.0 3.9e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.21 EWM26824.1 - 0.0012 18.5 0.0 0.0029 17.2 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase DAGAT PF03982.13 EWM26825.1 - 2.4e-29 102.2 0.0 3.3e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.21 EWM26825.1 - 0.00092 18.8 0.0 0.0023 17.6 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase APO_RNA-bind PF05634.11 EWM26826.1 - 0.038 13.3 0.1 0.058 12.8 0.1 1.2 1 0 0 1 1 1 0 APO RNA-binding CCB1 PF12046.8 EWM26827.1 - 0.23 10.8 3.8 0.68 9.3 0.2 2.1 1 1 0 2 2 2 0 Cofactor assembly of complex C subunit B Lectin_C PF00059.21 EWM26828.1 - 1.4e-25 90.1 3.7 2e-10 41.3 0.0 4.7 4 0 0 4 4 4 3 Lectin C-type domain UL45 PF05473.12 EWM26828.1 - 1.3e-08 34.7 6.7 0.067 12.8 0.1 3.4 3 0 0 3 3 3 3 UL45 protein, carbohydrate-binding C-type lectin-like WSC PF01822.19 EWM26828.1 - 2.4e-06 27.6 12.6 2.4e-06 27.6 12.6 2.3 2 0 0 2 2 2 1 WSC domain TPR_1 PF00515.28 EWM26829.1 - 6.2e-11 41.6 0.8 4.8e-06 26.2 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EWM26829.1 - 2.3e-08 33.5 3.5 0.00041 20.3 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EWM26829.1 - 1.4e-05 25.5 4.1 0.0043 17.8 0.1 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EWM26829.1 - 1.4e-05 24.9 0.9 0.091 13.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EWM26829.1 - 0.00083 20.0 1.4 0.00083 20.0 1.4 2.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EWM26829.1 - 0.0012 19.1 5.8 0.25 11.6 0.6 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EWM26829.1 - 0.0016 18.0 0.2 0.087 12.5 0.1 3.1 3 0 0 3 3 3 1 TPR repeat TPR_6 PF13174.6 EWM26829.1 - 0.0017 18.9 0.7 1.8 9.4 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.17 EWM26829.1 - 0.02 15.3 5.2 0.38 11.2 1.6 2.8 1 1 1 2 2 2 0 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.6 EWM26829.1 - 0.027 14.6 0.1 0.057 13.5 0.1 1.6 1 1 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat DUF3856 PF12968.7 EWM26829.1 - 0.034 14.2 0.2 0.098 12.7 0.2 1.8 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) TPR_10 PF13374.6 EWM26829.1 - 0.12 12.3 4.8 0.73 9.8 0.4 3.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 EWM26829.1 - 0.3 11.3 5.1 4.6 7.5 0.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EWM26829.1 - 0.32 11.1 3.8 20 5.5 0.2 3.4 2 2 0 2 2 2 0 Tetratricopeptide repeat IBR PF01485.21 EWM26830.1 - 0.041 14.1 13.5 0.076 13.2 13.5 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain HMG_CoA_synt_N PF01154.17 EWM26831.1 - 2.1e-80 268.7 0.1 4.4e-80 267.6 0.1 1.6 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 EWM26831.1 - 9.6e-78 261.6 0.0 1.7e-77 260.8 0.0 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal ketoacyl-synt PF00109.26 EWM26831.1 - 4.2e-14 52.8 3.3 1.1e-11 44.9 3.3 2.5 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EWM26831.1 - 1.7e-06 27.7 10.6 0.00027 20.7 3.1 4.4 3 1 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 EWM26831.1 - 0.0071 16.5 0.9 0.37 11.0 0.0 3.5 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DHHC PF01529.20 EWM26832.1 - 5.9e-35 120.3 9.1 5.9e-35 120.3 9.1 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase Rab5ip PF07019.12 EWM26832.1 - 0.36 11.4 3.3 0.92 10.1 2.8 1.9 1 1 1 2 2 2 0 Rab5-interacting protein (Rab5ip) DUF2070 PF09843.9 EWM26832.1 - 0.86 7.8 3.3 1.8 6.8 3.3 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Rhodanese PF00581.20 EWM26834.1 - 0.0038 17.7 0.0 0.068 13.7 0.0 2.7 2 1 0 2 2 2 1 Rhodanese-like domain Siva PF05458.12 EWM26835.1 - 2.3e-10 40.4 11.6 3.8e-10 39.7 11.6 1.3 1 0 0 1 1 1 1 Cd27 binding protein (Siva) Sugar_tr PF00083.24 EWM26836.1 - 7.2e-90 302.0 15.1 1.7e-52 178.8 1.1 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EWM26836.1 - 4.9e-17 61.9 29.7 4.9e-17 61.9 29.7 2.2 1 1 0 2 2 2 1 Major Facilitator Superfamily Mon1 PF03164.14 EWM26837.1 - 3.7e-79 266.7 0.0 1.9e-78 264.4 0.0 1.8 1 1 0 1 1 1 1 Trafficking protein Mon1 E3_UbLigase_R4 PF13764.6 EWM26839.1 - 5e-102 342.5 0.0 1.5e-49 169.0 0.0 3.4 2 1 0 2 2 2 2 E3 ubiquitin-protein ligase UBR4 ZZ PF00569.17 EWM26839.1 - 9.7e-07 28.5 4.1 9.7e-07 28.5 4.1 2.9 2 1 1 3 3 3 1 Zinc finger, ZZ type Siva PF05458.12 EWM26839.1 - 7.2 6.3 15.2 0.025 14.3 3.8 2.3 2 0 0 2 2 2 0 Cd27 binding protein (Siva) Longin PF13774.6 EWM26842.1 - 0.094 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Regulated-SNARE-like domain DUF2407_C PF13373.6 EWM26843.1 - 9.1e-23 81.0 0.4 1.7e-22 80.1 0.4 1.5 1 0 0 1 1 1 1 DUF2407 C-terminal domain ubiquitin PF00240.23 EWM26843.1 - 1.7e-08 34.1 0.0 2.6e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 EWM26843.1 - 0.0069 16.9 0.0 0.016 15.8 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Proteasome PF00227.26 EWM26844.1 - 1.1e-07 31.5 0.0 3.5e-06 26.6 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit ABC_membrane PF00664.23 EWM26845.1 - 2.8e-112 374.8 21.2 1.1e-60 205.6 1.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EWM26845.1 - 2.1e-69 232.3 0.0 6.9e-34 117.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 EWM26845.1 - 1.6e-10 41.6 0.4 0.00053 20.4 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 EWM26845.1 - 2.4e-09 36.7 0.0 0.0018 17.6 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin SMC_N PF02463.19 EWM26845.1 - 2.9e-09 36.7 3.1 0.0038 16.7 2.3 4.7 3 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EWM26845.1 - 4.6e-08 32.7 0.2 0.0075 16.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EWM26845.1 - 9.9e-08 32.1 0.0 0.0013 18.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase APS_kinase PF01583.20 EWM26845.1 - 3.2e-07 30.4 0.1 0.031 14.2 0.0 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase G-alpha PF00503.20 EWM26845.1 - 8.2e-06 25.2 0.0 0.035 13.3 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_22 PF13401.6 EWM26845.1 - 2e-05 24.9 1.7 0.43 10.9 0.1 3.6 2 2 0 2 2 2 2 AAA domain AAA_7 PF12775.7 EWM26845.1 - 6.4e-05 22.5 0.0 0.29 10.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_30 PF13604.6 EWM26845.1 - 6.6e-05 22.7 1.0 0.43 10.3 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.14 EWM26845.1 - 0.00015 21.7 0.2 1.5 8.8 0.0 3.4 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 EWM26845.1 - 0.00032 20.3 0.1 0.52 9.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 EWM26845.1 - 0.00055 20.2 0.1 1.3 9.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EWM26845.1 - 0.00062 20.3 0.0 2.5 8.6 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_21 PF13304.6 EWM26845.1 - 0.00064 19.6 0.2 5.2 6.8 0.0 3.4 3 1 1 4 4 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 EWM26845.1 - 0.00071 19.7 0.0 1.2 9.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 EWM26845.1 - 0.0013 18.9 0.1 1.3 9.1 0.0 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain DUF815 PF05673.13 EWM26845.1 - 0.0023 17.1 0.0 1.7 7.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 EWM26845.1 - 0.0033 17.5 0.3 1.2 9.3 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase KAP_NTPase PF07693.14 EWM26845.1 - 0.0066 15.7 0.0 2.6 7.2 0.0 2.3 2 0 0 2 2 2 1 KAP family P-loop domain AAA_15 PF13175.6 EWM26845.1 - 0.0076 16.0 0.0 0.26 10.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 EWM26845.1 - 0.013 14.9 2.1 2 7.7 0.0 2.6 3 0 0 3 3 2 0 FtsK/SpoIIIE family PRK PF00485.18 EWM26845.1 - 0.013 15.2 0.0 4.7 6.9 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.6 EWM26845.1 - 0.014 15.1 0.0 4.6 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EWM26845.1 - 0.016 15.5 5.0 6.2 7.1 0.5 4.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.23 EWM26845.1 - 0.019 15.0 0.3 1.7 8.6 0.0 2.8 3 0 0 3 3 2 0 Dynamin family ABC_ATPase PF09818.9 EWM26845.1 - 0.022 13.6 3.7 0.59 8.9 0.1 2.6 3 0 0 3 3 2 0 Predicted ATPase of the ABC class Sigma54_activat PF00158.26 EWM26845.1 - 0.032 14.0 0.0 4 7.1 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_23 PF13476.6 EWM26845.1 - 0.036 14.5 0.1 6 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain L51_S25_CI-B8 PF05047.16 EWM26845.1 - 0.05 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain NB-ARC PF00931.22 EWM26845.1 - 0.056 12.6 0.1 10 5.2 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain ATP_bind_1 PF03029.17 EWM26845.1 - 0.061 13.1 0.1 8.8 6.0 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 EWM26845.1 - 0.081 13.3 0.0 14 6.1 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Roc PF08477.13 EWM26845.1 - 0.085 13.1 0.2 15 5.8 0.0 2.9 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 EWM26845.1 - 0.095 12.6 1.0 43 4.0 0.0 3.3 3 0 0 3 3 3 0 NTPase ATP-synt_ab PF00006.25 EWM26845.1 - 0.1 12.2 0.0 9.8 5.8 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activ_2 PF14532.6 EWM26845.1 - 0.11 12.6 0.0 2 8.5 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_17 PF13207.6 EWM26845.1 - 0.13 12.7 1.8 8.6 6.8 0.0 3.5 4 0 0 4 4 3 0 AAA domain Mg_chelatase PF01078.21 EWM26845.1 - 0.13 11.6 0.0 4.1 6.7 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 EWM26845.1 - 0.15 12.0 3.0 10 6.0 0.1 3.1 4 0 0 4 4 3 0 NACHT domain Septin PF00735.18 EWM26845.1 - 0.2 10.9 0.1 6.9 5.9 0.0 2.2 2 0 0 2 2 2 0 Septin GRIP PF01465.20 EWM26846.1 - 1.3e-12 47.4 0.0 2.8e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 GRIP domain Bcr-Abl_Oligo PF09036.10 EWM26846.1 - 0.014 15.4 0.5 0.014 15.4 0.5 4.1 3 1 1 4 4 4 0 Bcr-Abl oncoprotein oligomerisation domain CTD_bind PF04818.13 EWM26848.1 - 0.034 15.0 0.0 0.1 13.4 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase II-binding domain. Thoc2 PF11732.8 EWM26848.1 - 0.22 11.6 0.1 0.9 9.6 0.0 1.9 2 0 0 2 2 2 0 Transcription- and export-related complex subunit UreF PF01730.16 EWM26850.1 - 1.6e-17 64.3 4.8 2.5e-17 63.7 4.8 1.3 1 0 0 1 1 1 1 UreF Vps16_N PF04841.13 EWM26851.1 - 2.1e-46 158.5 0.0 1e-21 77.2 0.0 3.1 3 0 0 3 3 3 3 Vps16, N-terminal region Vps16_C PF04840.12 EWM26851.1 - 9.4e-43 146.5 3.1 2.2e-29 102.5 0.9 2.9 2 1 0 2 2 2 2 Vps16, C-terminal region RsfS PF02410.15 EWM26852.1 - 9.6e-18 64.5 0.0 1.7e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation SCAB_CC PF16712.5 EWM26852.1 - 0.075 12.9 0.7 0.14 12.0 0.7 1.3 1 0 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein Abhydrolase_6 PF12697.7 EWM26853.1 - 7.7e-18 65.9 0.8 1.3e-17 65.1 0.5 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EWM26853.1 - 2e-12 46.9 0.0 4.5e-12 45.8 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EWM26853.1 - 4.6e-08 33.0 0.0 2e-07 30.9 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 EWM26853.1 - 0.00093 19.4 0.0 0.0017 18.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.13 EWM26853.1 - 0.002 18.0 0.0 0.004 17.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EWM26853.1 - 0.0049 16.7 0.2 0.69 9.7 0.3 2.5 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EWM26853.1 - 0.011 15.3 0.0 3.3 7.1 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF1869 PF08956.10 EWM26853.1 - 0.013 15.4 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1869) Abhydrolase_4 PF08386.10 EWM26853.1 - 0.021 14.9 0.0 0.072 13.2 0.0 1.9 2 0 0 2 2 2 0 TAP-like protein DLH PF01738.18 EWM26853.1 - 0.082 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Tfb4 PF03850.14 EWM26854.1 - 6.3e-70 235.8 1.0 6.2e-56 189.9 2.5 2.1 2 0 0 2 2 2 2 Transcription factor Tfb4 Tfb4 PF03850.14 EWM26855.1 - 8.5e-70 235.4 0.9 6.2e-56 189.9 2.5 2.1 2 0 0 2 2 2 2 Transcription factor Tfb4 Amino_oxidase PF01593.24 EWM26856.1 - 1.5e-24 87.1 0.0 7.7e-17 61.7 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EWM26856.1 - 2.8e-13 49.9 0.2 8.4e-13 48.3 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EWM26856.1 - 3.3e-10 40.1 0.3 2.2e-09 37.4 0.3 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EWM26856.1 - 1.2e-08 34.5 1.1 1.9e-07 30.5 0.9 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 EWM26856.1 - 1.1e-06 28.3 0.0 1.7e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EWM26856.1 - 5.7e-05 22.0 0.1 0.0022 16.7 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 EWM26856.1 - 0.00013 21.3 0.9 0.0045 16.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EWM26856.1 - 0.00042 20.8 0.8 0.0096 16.5 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EWM26856.1 - 0.001 18.4 0.2 0.0021 17.4 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EWM26856.1 - 0.0017 17.5 0.1 0.0023 17.1 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 EWM26856.1 - 0.0045 16.2 0.2 0.0083 15.4 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 EWM26856.1 - 0.068 12.2 0.0 0.14 11.1 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EWM26856.1 - 0.16 11.2 0.1 0.29 10.4 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 EWM26856.1 - 0.22 11.5 1.7 8.4 6.4 0.1 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding Lyase_1 PF00206.20 EWM26857.1 - 1.6e-85 287.3 0.0 2.3e-85 286.7 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 EWM26857.1 - 1.7e-23 83.1 0.0 5.1e-23 81.6 0.0 1.9 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Lyase_1 PF00206.20 EWM26858.1 - 8.7e-86 288.1 0.0 1.2e-85 287.7 0.0 1.2 1 0 0 1 1 1 1 Lyase Get5_bdg PF16843.5 EWM26858.1 - 0.18 11.3 0.1 9 5.9 0.0 2.4 2 0 0 2 2 2 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein DASH_Hsk3 PF08227.11 EWM26859.1 - 0.012 16.0 0.5 0.041 14.2 0.0 1.9 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like Sde2_N_Ubi PF13019.6 EWM26859.1 - 0.086 12.7 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain TPR_12 PF13424.6 EWM26860.1 - 8.9e-08 32.3 19.4 0.052 13.8 0.1 6.1 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 EWM26860.1 - 0.039 14.1 15.2 0.2 11.9 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 EWM26860.1 - 0.093 12.9 2.8 0.13 12.4 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat UPF0047 PF01894.17 EWM26862.1 - 4.1e-37 126.8 0.0 7.1e-37 126.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Rad60-SLD PF11976.8 EWM26863.1 - 1.2e-05 25.1 0.4 3e-05 23.7 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like GAS PF13851.6 EWM26863.1 - 0.006 16.0 18.1 0.01 15.2 18.1 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding ERM PF00769.19 EWM26863.1 - 0.02 14.7 22.8 0.035 13.9 22.8 1.5 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF4472 PF14739.6 EWM26863.1 - 0.14 12.9 15.9 0.042 14.6 11.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) V_ATPase_I PF01496.19 EWM26863.1 - 0.32 8.9 8.3 0.44 8.4 8.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6_N PF17675.1 EWM26863.1 - 0.5 10.9 29.4 0.1 13.2 24.4 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Tektin PF03148.14 EWM26863.1 - 0.64 8.7 21.7 1.8 7.2 14.7 2.2 1 1 1 2 2 2 0 Tektin family BLOC1_2 PF10046.9 EWM26863.1 - 0.71 10.2 8.4 0.85 10.0 6.5 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HSBP1 PF06825.12 EWM26863.1 - 0.76 9.7 4.7 0.22 11.4 0.5 2.4 2 1 0 2 2 1 0 Heat shock factor binding protein 1 DUF3450 PF11932.8 EWM26863.1 - 0.93 8.7 19.6 0.016 14.6 10.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF4407 PF14362.6 EWM26863.1 - 1.1 8.6 17.2 1.7 7.9 17.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fmp27_WPPW PF10359.9 EWM26863.1 - 2 7.2 12.2 3.4 6.4 12.2 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF1664 PF07889.12 EWM26863.1 - 2.6 8.1 5.1 6.9 6.7 4.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Vicilin_N PF04702.12 EWM26863.1 - 2.6 7.9 9.6 5.8 6.7 9.6 1.6 1 0 0 1 1 1 0 Vicilin N terminal region DUF4164 PF13747.6 EWM26863.1 - 3.2 8.1 24.4 0.052 13.8 10.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) HALZ PF02183.18 EWM26863.1 - 4 7.8 11.9 0.71 10.1 5.0 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper LMBR1 PF04791.16 EWM26863.1 - 5.6 5.7 4.8 7.6 5.3 4.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Cas_DxTHG PF09455.10 EWM26863.1 - 6.7 6.2 7.3 10 5.6 7.3 1.2 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family Matrilin_ccoil PF10393.9 EWM26863.1 - 7.3 6.5 7.5 0.94 9.4 0.5 3.1 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin FUSC PF04632.12 EWM26863.1 - 7.6 4.9 9.1 11 4.4 9.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Nup54 PF13874.6 EWM26863.1 - 7.9 6.6 15.8 15 5.7 15.8 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 PAP_fibrillin PF04755.12 EWM26864.1 - 4e-30 105.2 1.1 1.3e-24 87.2 0.0 2.0 1 1 1 2 2 2 2 PAP_fibrillin Sacchrp_dh_NADP PF03435.18 EWM26865.1 - 1.8e-12 47.7 0.0 9.1e-12 45.4 0.0 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain CENP-R PF06729.12 EWM26865.1 - 0.0031 17.4 0.0 0.0051 16.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component, CENP-R NAD_binding_10 PF13460.6 EWM26865.1 - 0.08 12.8 0.0 0.22 11.4 0.0 1.7 1 1 0 1 1 1 0 NAD(P)H-binding NmrA PF05368.13 EWM26865.1 - 0.092 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Pyr_redox_2 PF07992.14 EWM26866.1 - 1.2e-06 28.0 0.0 1.7e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF4448 PF14610.6 EWM26867.1 - 0.00018 21.4 0.0 0.00029 20.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Podoplanin PF05808.11 EWM26867.1 - 0.039 14.1 0.4 0.14 12.2 0.0 2.1 2 1 0 2 2 2 0 Podoplanin PPR_2 PF13041.6 EWM26868.1 - 1.6e-14 53.8 2.2 0.0012 19.0 0.0 7.1 7 2 3 10 10 10 4 PPR repeat family PPR_3 PF13812.6 EWM26868.1 - 1.5e-10 41.0 0.0 0.036 14.1 0.0 5.7 5 1 2 7 7 7 4 Pentatricopeptide repeat domain PPR_long PF17177.4 EWM26868.1 - 1.1e-09 37.9 0.5 0.0004 19.8 0.0 3.2 3 0 0 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 EWM26868.1 - 2.8e-07 30.3 16.9 0.93 9.9 0.0 9.3 10 0 0 10 10 10 3 PPR repeat ECSIT PF06239.11 EWM26868.1 - 0.07 12.2 0.1 0.2 10.8 0.1 1.8 1 1 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway CENP-Q PF13094.6 EWM26868.1 - 0.089 13.0 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Fer4_20 PF14691.6 EWM26869.1 - 0.0083 15.9 0.2 0.016 14.9 0.2 1.4 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster GATase_2 PF00310.21 EWM26870.1 - 7.2e-24 84.3 0.1 8.4e-24 84.1 0.1 1.0 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GXGXG PF01493.19 EWM26873.1 - 8.1e-18 64.7 0.0 1.1e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 GXGXG motif Myosin_head PF00063.21 EWM26874.1 - 2.3e-41 141.8 0.0 2.9e-41 141.5 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) ORC6 PF05460.13 EWM26874.1 - 0.44 9.8 1.5 0.57 9.4 1.5 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) COPI_assoc PF08507.10 EWM26875.1 - 0.00047 20.2 11.0 0.0012 18.9 11.0 1.7 1 1 0 1 1 1 1 COPI associated protein Cg6151-P PF10233.9 EWM26875.1 - 0.022 15.1 5.6 0.03 14.6 5.6 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein CG6151-P LapA_dom PF06305.11 EWM26875.1 - 0.17 11.7 0.1 0.17 11.7 0.1 2.7 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain YtpI PF14007.6 EWM26875.1 - 2.3 8.4 8.1 8.3 6.6 8.1 1.9 1 1 1 2 2 2 0 YtpI-like protein DUF3040 PF11239.8 EWM26875.1 - 5.1 7.4 9.0 14 6.0 4.8 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) DUF3487 PF11990.8 EWM26875.1 - 6.7 6.6 11.0 2 8.3 1.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3487) DUF373 PF04123.13 EWM26875.1 - 8.2 5.8 8.9 2.8 7.3 0.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF373) FoP_duplication PF13865.6 EWM26878.1 - 2.9e-14 53.4 21.9 2.9e-14 53.4 21.9 4.4 3 1 1 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 Nucleoporin_N PF08801.11 EWM26879.1 - 2.4e-08 33.2 0.0 2.9e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like HSP70 PF00012.20 EWM26880.1 - 4.2e-23 81.4 0.0 1.7e-22 79.4 0.0 1.7 2 0 0 2 2 2 1 Hsp70 protein BcrAD_BadFG PF01869.20 EWM26880.1 - 0.0003 20.4 0.0 0.00038 20.0 0.0 1.2 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family MreB_Mbl PF06723.13 EWM26880.1 - 0.0084 15.0 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 MreB/Mbl protein TLC PF03219.14 EWM26888.1 - 3.7e-08 32.5 0.6 4.1e-08 32.4 0.6 1.1 1 0 0 1 1 1 1 TLC ATP/ADP transporter UPF0016 PF01169.19 EWM26889.1 - 3.7e-10 40.0 0.2 7.1e-10 39.1 0.2 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0016 PI3_PI4_kinase PF00454.27 EWM26890.1 - 9.9e-63 212.3 0.0 1.4e-62 211.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EWM26890.1 - 9e-19 67.0 0.9 1.4e-18 66.4 0.0 1.8 2 0 0 2 2 2 1 FATC domain APH PF01636.23 EWM26890.1 - 0.02 14.8 0.2 0.075 12.9 0.3 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Mvb12 PF09452.10 EWM26890.1 - 0.15 12.5 0.0 0.41 11.1 0.0 1.7 1 0 0 1 1 1 0 ESCRT-I subunit Mvb12 DUF3446 PF11928.8 EWM26891.1 - 0.0038 17.5 1.1 0.0038 17.5 1.1 5.1 1 1 3 4 4 4 1 Early growth response N-terminal domain Cellulase PF00150.18 EWM26893.1 - 3.9e-34 118.4 0.1 4.7e-34 118.1 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Caf4 PF11615.8 EWM26893.1 - 0.1 12.6 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 CCR4-associated factor 4 PP2C PF00481.21 EWM26894.1 - 6.6e-35 121.0 0.0 3.7e-16 59.5 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EWM26894.1 - 0.0037 16.9 0.4 0.018 14.7 0.2 2.0 2 0 0 2 2 2 1 Protein phosphatase 2C Flavodoxin_2 PF02525.17 EWM26895.1 - 9.1e-30 103.8 0.0 1e-29 103.7 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 EWM26895.1 - 5.6e-12 45.7 0.0 9.5e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Mito_carr PF00153.27 EWM26896.1 - 9.3e-28 96.0 0.1 1e-14 54.2 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Cupin_8 PF13621.6 EWM26897.1 - 1e-15 58.2 0.0 1.5e-14 54.4 0.0 2.5 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 EWM26897.1 - 4.9e-14 52.7 0.2 4.7e-07 30.2 0.1 2.8 2 0 0 2 2 2 2 JmjC domain, hydroxylase Cupin_4 PF08007.12 EWM26897.1 - 0.063 12.7 0.0 0.16 11.4 0.0 1.5 1 1 0 1 1 1 0 Cupin superfamily protein Cupin_2 PF07883.11 EWM26897.1 - 0.1 12.3 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 Cupin domain RbsD_FucU PF05025.13 EWM26898.1 - 1.2e-37 129.3 0.0 1.4e-37 129.1 0.0 1.0 1 0 0 1 1 1 1 RbsD / FucU transport protein family DUF5590 PF17881.1 EWM26898.1 - 0.074 13.1 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5590) YTH PF04146.15 EWM26899.1 - 1.4e-34 119.4 0.1 1.4e-34 119.4 0.1 2.0 2 0 0 2 2 2 1 YT521-B-like domain Vac7 PF12751.7 EWM26900.1 - 0.044 13.2 0.0 0.059 12.8 0.0 1.3 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 NIF PF03031.18 EWM26902.1 - 7.5e-22 77.8 0.0 1.2e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 EWM26902.1 - 0.0015 18.2 0.1 0.0042 16.8 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin family Vac7 PF12751.7 EWM26903.1 - 0.041 13.3 0.3 0.098 12.1 0.3 1.6 1 1 0 1 1 1 0 Vacuolar segregation subunit 7 Vac7 PF12751.7 EWM26904.1 - 0.1 12.1 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 PCMT PF01135.19 EWM26905.1 - 5.7e-66 222.3 0.0 6.9e-66 222.0 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EWM26905.1 - 6.2e-11 42.3 0.0 1.1e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM26905.1 - 6.7e-10 39.5 0.0 1.2e-09 38.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EWM26905.1 - 2.2e-07 30.6 0.0 3.2e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EWM26905.1 - 3e-07 31.0 0.0 6e-07 30.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EWM26905.1 - 1.3e-06 28.4 0.0 1.9e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EWM26905.1 - 1.3e-06 28.0 0.0 1.9e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_3 PF01596.17 EWM26905.1 - 2.7e-06 26.7 0.0 7.7e-06 25.2 0.0 1.7 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_32 PF13679.6 EWM26905.1 - 3.3e-06 27.2 0.0 4.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 EWM26905.1 - 3.9e-06 26.7 0.0 4.9e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit MTS PF05175.14 EWM26905.1 - 8.5e-06 25.4 0.0 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 EWM26905.1 - 2.3e-05 23.8 0.0 3.2e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 EWM26905.1 - 0.00016 22.3 0.0 0.00032 21.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EWM26905.1 - 0.00021 20.8 0.0 0.00033 20.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase AviRa PF11599.8 EWM26905.1 - 0.00089 18.8 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 RRNA methyltransferase AviRa Methyltransf_18 PF12847.7 EWM26905.1 - 0.0013 18.7 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EWM26905.1 - 0.0049 15.8 0.0 0.0071 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) FtsJ PF01728.19 EWM26905.1 - 0.0049 17.0 0.0 0.0076 16.4 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase tRNA_U5-meth_tr PF05958.11 EWM26905.1 - 0.013 14.5 0.0 0.017 14.1 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase MetW PF07021.12 EWM26905.1 - 0.02 14.5 0.1 0.052 13.1 0.0 1.7 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Methyltr_RsmB-F PF01189.17 EWM26905.1 - 0.062 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 EWM26906.1 - 2.3e-39 135.3 0.0 3e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EWM26906.1 - 5.2e-11 42.6 0.0 7.5e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM26906.1 - 4.8e-09 36.8 0.0 9.5e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EWM26906.1 - 1.9e-07 30.8 0.0 2.9e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EWM26906.1 - 3.4e-07 30.8 0.0 7.8e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EWM26906.1 - 2.4e-06 27.6 0.0 3.5e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EWM26906.1 - 3.2e-06 26.7 0.0 4.9e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EWM26906.1 - 5e-06 26.5 0.0 7.5e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EWM26906.1 - 7.5e-06 25.6 0.1 1.1e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 EWM26906.1 - 2.1e-05 24.0 0.0 2.9e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase GCD14 PF08704.10 EWM26906.1 - 2.8e-05 23.9 0.0 3.9e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_3 PF01596.17 EWM26906.1 - 0.00011 21.5 0.0 0.00036 19.8 0.0 1.7 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_4 PF02390.17 EWM26906.1 - 0.00015 21.3 0.0 0.00024 20.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase AviRa PF11599.8 EWM26906.1 - 0.00066 19.2 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 RRNA methyltransferase AviRa Methyltransf_12 PF08242.12 EWM26906.1 - 0.0011 19.6 0.0 0.0024 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EWM26906.1 - 0.0017 18.3 0.0 0.0027 17.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EWM26906.1 - 0.0037 16.2 0.0 0.0051 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) FtsJ PF01728.19 EWM26906.1 - 0.0045 17.1 0.0 0.0075 16.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase tRNA_U5-meth_tr PF05958.11 EWM26906.1 - 0.0083 15.1 0.0 0.0096 14.9 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase MetW PF07021.12 EWM26906.1 - 0.012 15.3 0.1 0.033 13.8 0.0 1.8 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Methyltr_RsmB-F PF01189.17 EWM26906.1 - 0.047 13.3 0.0 0.071 12.7 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Ribosomal_S10 PF00338.22 EWM26907.1 - 4.4e-24 84.6 0.6 5.3e-24 84.3 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e RACo_linker PF17650.1 EWM26907.1 - 0.062 13.2 0.0 1.9 8.4 0.0 2.2 1 1 1 2 2 2 0 RACo linker region PriA_C PF18074.1 EWM26907.1 - 0.065 14.1 0.2 0.13 13.1 0.1 1.5 2 0 0 2 2 2 0 Primosomal protein N C-terminal domain TRM13 PF05206.14 EWM26907.1 - 0.089 12.3 0.3 0.13 11.8 0.3 1.2 1 0 0 1 1 1 0 Methyltransferase TRM13 Utp12 PF04003.12 EWM26907.1 - 0.09 13.1 0.2 8.3 6.8 0.1 2.0 2 0 0 2 2 2 0 Dip2/Utp12 Family GBR2_CC PF18455.1 EWM26907.1 - 0.28 11.3 0.2 0.28 11.3 0.2 2.1 2 1 1 3 3 3 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain YpsA PF06908.11 EWM26909.1 - 0.054 13.5 0.0 0.076 13.0 0.0 1.2 1 0 0 1 1 1 0 YspA SLOG family LRR_6 PF13516.6 EWM26910.1 - 0.018 15.1 0.0 2.4 8.5 0.0 4.1 3 0 0 3 3 3 0 Leucine Rich repeat F-box PF00646.33 EWM26910.1 - 0.039 13.8 0.4 0.16 11.9 0.4 2.2 1 0 0 1 1 1 0 F-box domain LRR_1 PF00560.33 EWM26910.1 - 0.29 11.8 1.2 1.1e+02 3.9 0.0 5.2 4 0 0 4 4 4 0 Leucine Rich Repeat Arrestin_N PF00339.29 EWM26911.1 - 8.1e-09 35.7 0.0 2.6e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EWM26911.1 - 1.3e-08 35.4 0.0 0.0021 18.5 0.0 2.9 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain ChlI PF13541.6 EWM26911.1 - 0.13 12.1 0.0 15 5.5 0.0 2.4 2 0 0 2 2 2 0 Subunit ChlI of Mg-chelatase Cys_Met_Meta_PP PF01053.20 EWM26911.1 - 0.16 10.5 0.0 0.3 9.6 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DNA_pol3_alpha PF07733.12 EWM26911.1 - 0.21 11.2 0.0 0.43 10.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha NTPase domain Methyltransf_31 PF13847.6 EWM26913.1 - 1.2e-13 51.1 0.0 2.4e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM26913.1 - 1.9e-10 41.3 0.0 9.5e-10 39.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EWM26913.1 - 7.7e-09 35.3 0.0 1.5e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EWM26913.1 - 2e-08 34.4 4.5 6.5e-08 32.7 0.4 3.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EWM26913.1 - 5.4e-06 27.1 0.0 2.8e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM26913.1 - 0.00029 21.4 0.0 0.00093 19.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EWM26913.1 - 0.0015 18.3 0.0 0.015 15.0 0.0 2.1 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 EWM26913.1 - 0.0035 16.8 0.0 0.0068 15.9 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase GidB PF02527.15 EWM26913.1 - 0.0036 16.6 0.0 0.0077 15.6 0.0 1.5 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G PrmA PF06325.13 EWM26913.1 - 0.015 14.7 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 EWM26913.1 - 0.03 13.6 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_23 PF13489.6 EWM26913.1 - 0.031 14.1 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 EWM26913.1 - 0.13 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Cyclin_N PF00134.23 EWM26914.1 - 6.5e-28 97.0 0.0 8.5e-25 86.9 0.0 2.3 1 1 1 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 EWM26914.1 - 1.7e-22 79.7 0.1 3.6e-22 78.7 0.1 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain F-box-like PF12937.7 EWM26914.1 - 0.0071 16.2 0.1 0.022 14.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EWM26914.1 - 0.016 15.1 0.2 0.63 10.0 0.0 2.7 2 0 0 2 2 2 0 F-box domain ING PF12998.7 EWM26914.1 - 0.16 12.5 0.0 0.39 11.3 0.0 1.5 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding EcKinase PF02958.20 EWM26915.1 - 0.32 10.3 3.6 0.57 9.4 3.6 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase MFS_1 PF07690.16 EWM26916.1 - 2.8e-52 177.8 29.6 2.8e-52 177.8 29.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EWM26916.1 - 1.9e-09 36.9 8.1 3.3e-09 36.1 7.9 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 EWM26916.1 - 0.00064 18.1 2.9 0.2 9.9 0.0 3.4 2 2 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family BT1 PF03092.16 EWM26916.1 - 0.0064 14.8 4.4 0.0075 14.6 0.0 2.2 2 0 0 2 2 2 1 BT1 family Pkinase PF00069.25 EWM26917.1 - 1.9e-31 109.4 0.0 2e-30 106.1 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM26917.1 - 7e-09 35.4 0.0 2e-08 33.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EWM26917.1 - 0.00087 19.3 0.1 0.0026 17.7 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EWM26917.1 - 0.0014 17.4 0.0 0.0029 16.5 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EWM26917.1 - 0.0054 16.3 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.11 EWM26917.1 - 0.041 13.0 0.0 0.068 12.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Polyketide_cyc PF03364.20 EWM26918.1 - 1.8e-16 60.5 0.3 2.7e-16 60.0 0.3 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 EWM26918.1 - 2.8e-09 37.4 0.1 6.3e-09 36.2 0.1 1.6 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport CutA1 PF03091.15 EWM26918.1 - 0.016 15.0 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein COXG PF06240.13 EWM26918.1 - 0.19 11.5 0.0 0.46 10.2 0.0 1.6 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit G (CoxG) Coatomer_E PF04733.14 EWM26919.1 - 9.2e-36 123.7 0.1 1e-35 123.6 0.1 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 EWM26919.1 - 5.3e-07 30.0 2.1 2.1e-05 24.9 0.5 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EWM26919.1 - 3.7e-06 27.5 1.2 1e-05 26.0 0.4 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EWM26919.1 - 1.2e-05 25.6 0.0 0.057 14.1 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EWM26919.1 - 1.2e-05 25.0 1.0 4e-05 23.4 0.2 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EWM26919.1 - 0.0001 21.9 0.0 0.00036 20.2 0.2 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EWM26919.1 - 0.00056 20.1 1.8 0.0017 18.6 0.5 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EWM26919.1 - 0.0019 18.3 0.1 0.0041 17.2 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EWM26919.1 - 0.003 17.6 0.1 0.006 16.6 0.1 1.5 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 EWM26919.1 - 0.0074 16.2 0.1 0.022 14.8 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 EWM26919.1 - 0.012 16.0 0.5 0.67 10.5 0.1 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EWM26919.1 - 0.014 15.3 0.6 0.047 13.6 0.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EWM26919.1 - 0.028 15.2 1.2 0.76 10.8 0.1 3.3 1 1 3 4 4 4 0 Tetratricopeptide repeat Benyvirus_P25 PF05744.11 EWM26919.1 - 0.048 12.9 0.0 0.063 12.6 0.0 1.1 1 0 0 1 1 1 0 Benyvirus P25/P26 protein Type_III_YscG PF09477.10 EWM26919.1 - 0.1 12.7 0.1 5.7 7.1 0.0 2.2 1 1 1 2 2 2 0 Bacterial type II secretion system chaperone protein (type_III_yscG) Ion_trans PF00520.31 EWM26920.1 - 2.1e-15 56.6 47.1 1.7e-08 34.0 15.9 2.2 2 0 0 2 2 2 2 Ion transport protein Phage_Gp23 PF10669.9 EWM26920.1 - 0.031 14.6 4.6 1.9 8.9 0.0 3.8 3 0 0 3 3 3 0 Protein gp23 (Bacteriophage A118) SLATT_4 PF18186.1 EWM26920.1 - 0.037 13.7 0.0 0.096 12.3 0.0 1.7 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 DUF3493 PF11998.8 EWM26921.1 - 4.7e-22 78.0 0.7 1.1e-21 76.8 0.2 1.8 2 0 0 2 2 2 1 Low psii accumulation1 / Rep27 FixS PF03597.15 EWM26921.1 - 1.8 8.3 3.5 3.3 7.5 0.1 2.8 3 0 0 3 3 3 0 Cytochrome oxidase maturation protein cbb3-type RNA_pol_Rpc34 PF05158.12 EWM26922.1 - 4.8e-51 174.1 0.5 6.2e-51 173.8 0.5 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.12 EWM26922.1 - 0.043 14.0 0.6 0.074 13.2 0.6 1.4 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC RNA_pol_Rpc34 PF05158.12 EWM26923.1 - 2e-57 195.1 0.5 1.3e-50 172.7 0.2 2.0 1 1 1 2 2 2 2 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.12 EWM26923.1 - 0.035 14.3 0.6 0.065 13.4 0.6 1.4 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC RNA_pol_Rpc34 PF05158.12 EWM26924.1 - 4.8e-51 174.1 0.5 6.2e-51 173.8 0.5 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.12 EWM26924.1 - 0.043 14.0 0.6 0.074 13.2 0.6 1.4 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC IBR PF01485.21 EWM26925.1 - 8.5e-15 54.7 40.6 1.8e-09 37.7 8.1 4.3 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain Myb_DNA-binding PF00249.31 EWM26926.1 - 4.6e-11 42.7 0.3 2.2e-10 40.5 0.1 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain ZZ PF00569.17 EWM26926.1 - 4.4e-06 26.4 3.5 4.4e-06 26.4 3.5 2.0 2 0 0 2 2 2 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 EWM26926.1 - 0.00013 22.2 0.1 0.00049 20.3 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Sgf11 PF08209.11 EWM26926.1 - 0.56 9.8 0.1 0.56 9.8 0.1 2.1 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) VGCC_beta4Aa_N PF12052.8 EWM26926.1 - 6.7 6.9 8.2 19 5.4 8.2 1.9 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal Coatomer_E PF04733.14 EWM26927.1 - 9.1e-13 48.3 0.0 1.1e-12 48.0 0.0 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit Glyoxal_oxid_N PF07250.11 EWM26927.1 - 0.1 11.8 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus SWIRM PF04433.17 EWM26928.1 - 6.4e-05 23.2 0.0 0.00037 20.8 0.0 2.0 1 1 0 1 1 1 1 SWIRM domain WD40 PF00400.32 EWM26929.1 - 1.7e-05 25.4 12.9 0.2 12.6 1.6 5.1 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM26929.1 - 0.011 16.0 0.0 0.064 13.6 0.0 2.2 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DUF3934 PF13070.6 EWM26929.1 - 0.84 10.2 3.1 2 8.9 3.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3934) RIO1 PF01163.22 EWM26930.1 - 7.8e-53 178.9 0.0 1.9e-26 92.8 0.0 2.2 2 0 0 2 2 2 2 RIO1 family APH PF01636.23 EWM26930.1 - 1.7e-07 31.4 0.2 2.8e-05 24.2 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EWM26930.1 - 0.0075 15.1 0.1 0.017 13.9 0.1 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EWM26930.1 - 0.018 14.4 1.7 0.11 11.8 0.6 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family SRPRB PF09439.10 EWM26931.1 - 2.2e-36 125.0 0.0 3.2e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 EWM26931.1 - 9.8e-15 54.4 0.0 1.4e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EWM26931.1 - 5.7e-07 29.6 0.0 1.1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EWM26931.1 - 0.00022 21.4 0.0 0.00046 20.4 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EWM26931.1 - 0.00076 18.9 0.0 0.00094 18.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EWM26931.1 - 0.0013 18.3 0.0 0.23 11.0 0.0 2.2 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain cobW PF02492.19 EWM26931.1 - 0.0095 15.5 0.1 1.1 8.9 0.0 2.2 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 EWM26931.1 - 0.011 16.0 0.0 0.034 14.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EWM26931.1 - 0.013 15.9 0.0 0.036 14.5 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain Ras PF00071.22 EWM26931.1 - 0.018 14.7 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Ras family ATP_bind_1 PF03029.17 EWM26931.1 - 0.061 13.1 0.0 1.6 8.5 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein NYAP_N PF15439.6 EWM26931.1 - 0.097 11.9 0.2 0.15 11.2 0.2 1.2 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter AAA_7 PF12775.7 EWM26931.1 - 0.14 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 EWM26931.1 - 0.17 11.9 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EWM26931.1 - 0.2 11.8 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 EWM26931.1 - 0.24 10.5 0.0 2.6 7.1 0.0 2.0 1 1 1 2 2 2 0 G-protein alpha subunit PorB PF11565.8 EWM26933.1 - 0.28 11.6 2.1 1.1 9.7 0.4 2.2 2 0 0 2 2 2 0 Alpha helical Porin B Fascin PF06268.13 EWM26935.1 - 5.4e-05 23.4 0.0 7.5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Fascin domain FRG1 PF06229.12 EWM26935.1 - 0.00056 19.7 0.0 0.00063 19.5 0.0 1.2 1 0 0 1 1 1 1 FRG1-like domain ATP_sub_h PF10775.9 EWM26935.1 - 0.081 12.9 0.2 0.13 12.3 0.2 1.3 1 0 0 1 1 1 0 ATP synthase complex subunit h Mis12 PF05859.12 EWM26940.1 - 7.6e-09 35.7 0.0 9.9e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Mis12 protein zf_CCCH_4 PF18345.1 EWM26941.1 - 4.9e-06 26.4 1.7 1e-05 25.4 1.7 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 EWM26941.1 - 6e-05 22.8 0.9 0.00012 21.9 0.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EWM26941.1 - 6.5e-05 22.6 0.7 0.00012 21.7 0.7 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EWM26941.1 - 0.022 15.3 0.5 0.043 14.3 0.5 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 EWM26941.1 - 0.27 11.9 2.1 0.4 11.4 0.1 2.0 2 0 0 2 2 2 0 Torus domain CrgA PF06781.12 EWM26944.1 - 0.048 13.7 0.0 0.09 12.8 0.0 1.6 1 0 0 1 1 1 0 Cell division protein CrgA Synthase_beta PF11421.8 EWM26944.1 - 3.2 8.5 10.3 0.68 10.7 4.6 2.2 2 0 0 2 2 2 0 ATP synthase F1 beta subunit SNARE_assoc PF09335.11 EWM26945.1 - 4.7e-08 33.5 3.3 6.7e-08 33.0 0.8 2.0 2 0 0 2 2 2 1 SNARE associated Golgi protein CrgA PF06781.12 EWM26945.1 - 0.054 13.6 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 Cell division protein CrgA Phage_holin_3_6 PF07332.11 EWM26945.1 - 2.6 8.1 6.0 1.9 8.6 0.2 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III SASA PF03629.18 EWM26950.1 - 0.00044 20.0 0.1 0.0062 16.2 0.1 2.1 1 1 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase E3_binding PF02817.17 EWM26950.1 - 0.54 10.7 2.6 2.4 8.6 2.6 2.3 1 1 0 1 1 1 0 e3 binding domain Ig_mannosidase PF17753.1 EWM26951.1 - 1.3e-18 66.5 0.0 1.9e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Ig-fold domain EamA PF00892.20 EWM26952.1 - 0.00014 22.1 27.7 0.0058 16.8 5.2 3.8 3 1 0 3 3 3 2 EamA-like transporter family Rab5ip PF07019.12 EWM26953.1 - 2.2e-13 50.6 6.4 2.7e-13 50.3 6.4 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Cyd_oper_YbgE PF09600.10 EWM26953.1 - 0.26 11.7 5.8 5.6 7.4 0.8 2.4 2 0 0 2 2 2 0 Cyd operon protein YbgE (Cyd_oper_YbgE) BING4CT PF08149.11 EWM26955.1 - 0.033 14.0 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 BING4CT (NUC141) domain Acid_PPase PF12689.7 EWM26956.1 - 7.7e-18 64.9 0.1 8.5e-13 48.5 0.0 2.5 1 1 1 2 2 2 2 Acid Phosphatase DUF2608 PF11019.8 EWM26956.1 - 0.017 14.6 0.0 0.076 12.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) WD40 PF00400.32 EWM26958.1 - 1e-14 54.6 0.8 7.2e-11 42.5 0.2 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM26958.1 - 2.6e-06 27.6 0.0 0.00016 21.9 0.0 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EWM26958.1 - 5.5e-06 25.6 0.2 0.0028 16.7 0.0 2.1 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein LisH_TPL PF17814.1 EWM26959.1 - 1.3e-16 59.9 0.9 2.2e-16 59.2 0.9 1.4 1 0 0 1 1 1 1 LisH-like dimerisation domain WD40 PF00400.32 EWM26959.1 - 2.1e-15 56.8 0.1 0.00015 22.5 0.0 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EWM26959.1 - 9.7e-08 31.3 0.0 0.012 14.7 0.0 2.3 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 EWM26959.1 - 1.1e-07 32.0 0.0 1.6e-06 28.3 0.0 2.3 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain DUF5100 PF17029.5 EWM26959.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5100) DUF1682 PF07946.14 EWM26962.1 - 3.3e-29 102.1 0.0 4.2e-29 101.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF1772 PF08592.11 EWM26963.1 - 1.1 9.6 7.7 2.3 8.5 0.3 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF1772) DUF1682 PF07946.14 EWM26964.1 - 6.1e-17 61.8 5.0 7.6e-17 61.5 5.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Presenilin PF01080.17 EWM26964.1 - 0.29 9.8 1.7 0.32 9.7 1.7 1.0 1 0 0 1 1 1 0 Presenilin PIEZO PF15917.5 EWM26964.1 - 0.66 9.4 11.2 0.84 9.1 11.2 1.0 1 0 0 1 1 1 0 Piezo Radial_spoke_3 PF06098.11 EWM26964.1 - 2.7 7.2 18.9 3.3 6.9 18.9 1.1 1 0 0 1 1 1 0 Radial spoke protein 3 zf-MYND PF01753.18 EWM26966.1 - 7.5e-08 32.3 8.1 7.5e-08 32.3 8.1 2.3 2 0 0 2 2 2 1 MYND finger TspO_MBR PF03073.15 EWM26967.1 - 1.9e-05 24.7 0.7 1.9e-05 24.7 0.7 2.2 2 1 0 3 3 3 1 TspO/MBR family CBP_BcsN PF17038.5 EWM26967.1 - 0.049 13.0 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsN DAP3 PF10236.9 EWM26968.1 - 3e-20 72.6 0.0 5.1e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 EWM26968.1 - 2.4e-05 24.8 0.0 4.5e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 EWM26968.1 - 0.0048 16.0 0.0 0.0074 15.4 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase_2 PF01637.18 EWM26968.1 - 0.16 11.8 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 EWM26968.1 - 0.19 12.1 0.0 0.56 10.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain RabGAP-TBC PF00566.18 EWM26970.1 - 2e-25 89.7 0.0 2.7e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SDA1 PF05285.12 EWM26971.1 - 0.017 14.6 7.6 0.019 14.4 7.6 1.2 1 0 0 1 1 1 0 SDA1 DUF2052 PF09747.9 EWM26971.1 - 1.1 9.4 14.8 1.3 9.1 14.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) FAM176 PF14851.6 EWM26971.1 - 3.3 7.3 11.4 5.1 6.7 11.4 1.3 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.12 EWM26971.1 - 4.5 5.4 15.3 5.3 5.1 15.3 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EWM26971.1 - 5.6 5.1 12.9 6.7 4.9 12.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 EWM26971.1 - 7.1 4.6 18.0 8.6 4.3 18.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi CobT PF06213.12 EWM26971.1 - 7.4 5.9 16.1 10 5.4 16.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Mpp10 PF04006.12 EWM26971.1 - 7.8 4.8 16.8 9.2 4.6 16.8 1.0 1 0 0 1 1 1 0 Mpp10 protein BSP_II PF05432.11 EWM26971.1 - 9 5.9 22.2 11 5.6 22.2 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Cupin_4 PF08007.12 EWM26972.1 - 5.3e-13 49.1 0.2 0.0002 20.9 0.0 3.2 3 0 0 3 3 3 3 Cupin superfamily protein Cupin_8 PF13621.6 EWM26972.1 - 1.4e-12 47.9 0.0 2.4e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 EWM26972.1 - 0.024 14.4 0.0 0.54 10.0 0.0 2.6 2 0 0 2 2 2 0 Cupin domain JmjC PF02373.22 EWM26972.1 - 0.14 12.6 0.0 0.64 10.5 0.0 1.9 2 0 0 2 2 2 0 JmjC domain, hydroxylase SIS PF01380.22 EWM26972.1 - 0.2 11.5 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 SIS domain CorA PF01544.18 EWM26973.1 - 1.2e-29 103.6 0.5 1.1e-27 97.1 0.1 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein EF-hand_6 PF13405.6 EWM26973.1 - 0.00062 19.5 0.0 0.39 10.8 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EWM26973.1 - 0.007 15.8 0.0 0.11 12.1 0.0 2.4 2 0 0 2 2 2 1 EF hand ET PF01684.16 EWM26974.1 - 0.051 13.9 1.2 0.12 12.8 1.2 1.6 1 0 0 1 1 1 0 ET module Glyoxalase PF00903.25 EWM26975.1 - 6.5e-14 52.2 0.0 8.5e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EWM26975.1 - 9.8e-10 38.7 0.0 1.3e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EWM26975.1 - 0.0026 18.5 0.0 0.0035 18.1 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 EWM26975.1 - 0.03 14.5 0.0 0.053 13.6 0.0 1.4 1 1 0 1 1 1 0 Glyoxalase-like domain Hist_deacetyl PF00850.19 EWM26976.1 - 2.6e-61 207.8 0.0 3.3e-61 207.4 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Aminotran_1_2 PF00155.21 EWM26977.1 - 4.8e-40 137.8 0.0 5.9e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EWM26977.1 - 0.063 12.5 0.0 0.14 11.4 0.0 1.5 2 0 0 2 2 2 0 Beta-eliminating lyase PIG-S PF10510.9 EWM26978.1 - 2.1e-07 30.2 0.0 2.5e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein DSHCT PF08148.12 EWM26979.1 - 8.9e-51 171.8 0.2 3.9e-50 169.7 0.1 2.0 2 0 0 2 2 2 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 EWM26979.1 - 2.2e-16 60.6 0.0 2.6e-15 57.1 0.0 2.2 1 1 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.31 EWM26979.1 - 7.9e-07 29.4 0.0 2.3e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Phage_holin_5_1 PF06946.11 EWM26980.1 - 0.13 12.7 1.1 0.37 11.2 0.2 2.1 2 0 0 2 2 2 0 Bacteriophage A118-like holin, Hol118 RPN6_N PF18055.1 EWM26981.1 - 1e-35 122.6 0.9 1e-35 122.6 0.9 2.2 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 EWM26981.1 - 4e-15 56.2 0.4 7.3e-14 52.1 0.1 2.9 3 0 0 3 3 3 1 PCI domain RPN6_C_helix PF18503.1 EWM26981.1 - 1.8e-07 30.8 0.0 5.7e-07 29.2 0.0 1.9 2 0 0 2 2 2 1 26S proteasome subunit RPN6 C-terminal helix domain DUF410 PF04190.13 EWM26981.1 - 0.019 14.8 0.1 4.6 7.0 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF410) RPN7 PF10602.9 EWM26981.1 - 0.047 13.4 0.1 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 26S proteasome subunit RPN7 DDRGK PF09756.9 EWM26981.1 - 0.075 12.6 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 DDRGK domain DUF630 PF04783.12 EWM26981.1 - 0.1 12.8 1.0 2.9 8.1 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF630) TPR_7 PF13176.6 EWM26981.1 - 0.47 10.6 2.4 1.7 8.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EWM26981.1 - 5.3 7.4 16.4 3.5 8.0 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 EWM26981.1 - 6.6 7.1 20.6 0.79 10.1 3.4 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat DoxX_3 PF13781.6 EWM26983.1 - 0.013 16.1 0.5 0.013 16.1 0.5 1.7 2 0 0 2 2 2 0 DoxX-like family GATA PF00320.27 EWM26983.1 - 0.068 12.8 0.9 0.11 12.1 0.9 1.3 1 0 0 1 1 1 0 GATA zinc finger Virul_fac_BrkB PF03631.15 EWM26983.1 - 0.55 9.8 9.5 0.59 9.7 5.9 2.3 2 1 0 2 2 2 0 Virulence factor BrkB MASE3 PF17159.4 EWM26983.1 - 1.2 8.8 5.6 0.13 11.9 1.2 1.5 2 0 0 2 2 2 0 Membrane-associated sensor domain EBP PF05241.12 EWM26984.1 - 1.6e-47 161.3 1.3 1.6e-47 161.3 1.3 1.9 2 0 0 2 2 2 1 Emopamil binding protein DUF716 PF04819.12 EWM26984.1 - 0.022 14.4 0.5 0.044 13.4 0.3 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF716) TctB PF07331.11 EWM26984.1 - 0.7 10.2 10.0 1.9 8.8 9.0 2.0 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family MPC PF03650.13 EWM26988.1 - 5.7e-36 123.0 0.1 6.3e-36 122.9 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers DUF5489 PF17592.2 EWM26988.1 - 0.036 14.6 0.0 0.05 14.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5489) CorA PF01544.18 EWM26989.1 - 3.8e-20 72.4 0.4 1.3e-16 60.8 0.1 2.4 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Polyketide_cyc PF03364.20 EWM26990.1 - 1.2e-14 54.7 0.0 1.5e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport FAM104 PF15434.6 EWM26991.1 - 0.086 13.4 0.1 0.11 13.1 0.1 1.2 1 0 0 1 1 1 0 Family 104 DUF1180 PF06679.12 EWM26991.1 - 2 8.8 4.7 1.3 9.4 1.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) DEAD PF00270.29 EWM26992.1 - 1.4e-11 44.5 0.0 1.9e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EWM26992.1 - 0.021 14.9 0.0 0.024 14.6 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 EWM26992.1 - 0.15 12.0 0.0 0.18 11.7 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea LON_substr_bdg PF02190.16 EWM26994.1 - 3.1e-14 53.3 0.0 3.8e-14 53.1 0.0 1.0 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Mannitol_dh_C PF08125.13 EWM26995.1 - 7.1e-66 222.2 0.0 1.1e-65 221.5 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 EWM26995.1 - 4e-34 117.9 0.0 1.5e-25 90.1 0.0 2.6 2 0 0 2 2 2 2 Mannitol dehydrogenase Rossmann domain SNF2_N PF00176.23 EWM26996.1 - 4.3e-81 272.4 0.0 7.3e-81 271.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EWM26996.1 - 4.6e-07 30.2 0.7 8.5e-07 29.3 0.1 1.9 2 0 0 2 2 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 EWM26996.1 - 5.5e-07 29.4 9.5 5.5e-07 29.4 9.5 2.6 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 EWM26996.1 - 2.9e-06 27.1 6.4 2.9e-06 27.1 6.4 3.6 3 0 0 3 3 3 1 PHD-finger zf-C3HC4_3 PF13920.6 EWM26996.1 - 6.8e-06 25.8 9.1 6.8e-06 25.8 9.1 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EWM26996.1 - 1.1e-05 25.4 6.7 4.5e-05 23.4 6.7 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EWM26996.1 - 2.5e-05 24.1 8.9 2.5e-05 24.1 8.9 3.3 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 EWM26996.1 - 2.6e-05 24.5 8.6 2.6e-05 24.5 8.6 4.3 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 EWM26996.1 - 0.00051 19.8 9.3 0.00051 19.8 9.3 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EWM26996.1 - 3.4 7.6 19.5 0.061 13.2 11.0 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EWM26996.1 - 3.7 7.4 16.7 0.016 15.0 6.8 2.3 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain 14-3-3 PF00244.20 EWM26996.1 - 4.3 6.8 15.4 0.25 10.8 0.5 2.9 3 0 0 3 3 3 0 14-3-3 protein LYTB PF02401.18 EWM26997.1 - 2.5e-77 259.7 0.1 3e-77 259.4 0.1 1.1 1 0 0 1 1 1 1 LytB protein Cellulose_synt PF03552.14 EWM26998.1 - 1.7e-29 102.9 7.2 4.8e-19 68.4 2.2 3.2 1 1 2 3 3 3 3 Cellulose synthase Glyco_tranf_2_3 PF13641.6 EWM26998.1 - 2.9e-17 63.3 0.0 6.5e-17 62.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EWM26998.1 - 5.2e-17 62.4 2.9 5.2e-17 62.4 2.9 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EWM26998.1 - 3e-12 46.7 0.0 6.1e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EWM26998.1 - 7.8e-11 41.7 0.0 3.5e-10 39.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 EWM26998.1 - 0.00035 19.3 0.0 0.2 10.2 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase ABC_membrane PF00664.23 EWM26999.1 - 1.2e-50 172.7 3.9 1.4e-50 172.4 3.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_membrane_3 PF13748.6 EWM26999.1 - 0.11 11.7 1.7 0.12 11.6 0.6 1.5 2 0 0 2 2 2 0 ABC transporter transmembrane region ABC_membrane PF00664.23 EWM27000.1 - 2.8e-50 171.5 3.9 3.5e-50 171.2 3.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EWM27000.1 - 1.5e-28 100.0 0.0 2.8e-28 99.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 EWM27000.1 - 0.00018 21.8 0.1 0.001 19.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 EWM27000.1 - 0.00085 18.8 0.0 0.089 12.2 0.0 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EWM27000.1 - 0.0038 17.6 0.1 0.015 15.7 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 EWM27000.1 - 0.014 15.2 0.1 0.31 10.7 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein ABC_ATPase PF09818.9 EWM27000.1 - 0.031 13.1 0.0 0.054 12.3 0.0 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_18 PF13238.6 EWM27000.1 - 0.066 13.8 0.0 0.2 12.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain Rad17 PF03215.15 EWM27000.1 - 0.073 13.0 0.2 0.33 10.8 0.0 2.1 3 0 0 3 3 3 0 Rad17 P-loop domain Mg_chelatase PF01078.21 EWM27000.1 - 0.079 12.3 0.0 0.24 10.8 0.0 1.8 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 EWM27000.1 - 0.092 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EWM27000.1 - 0.12 12.3 0.1 6.1 6.7 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA PF00004.29 EWM27000.1 - 0.15 12.5 0.1 1.8 9.0 0.1 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PRK PF00485.18 EWM27000.1 - 0.19 11.5 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Lon_C PF05362.13 EWM27001.1 - 1.5e-69 233.7 0.9 4.3e-69 232.2 0.1 2.0 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 EWM27001.1 - 1.5e-22 80.4 0.0 3.3e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 EWM27001.1 - 3.9e-07 29.9 0.0 1.4e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 EWM27001.1 - 1.5e-05 25.2 0.0 5.3e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EWM27001.1 - 5.3e-05 23.2 0.0 9.2e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.11 EWM27001.1 - 8.1e-05 21.7 0.0 0.00017 20.7 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 EWM27001.1 - 0.0002 21.1 0.0 0.00062 19.5 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EWM27001.1 - 0.0027 18.0 2.7 0.15 12.3 0.2 3.4 3 1 0 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 EWM27001.1 - 0.0045 16.9 0.1 0.033 14.1 0.0 2.4 3 0 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 EWM27001.1 - 0.0047 17.3 0.2 0.0047 17.3 0.2 2.6 3 1 0 3 3 3 1 AAA ATPase domain AAA_23 PF13476.6 EWM27001.1 - 0.0047 17.4 5.0 0.23 12.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EWM27001.1 - 0.0098 15.6 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 EWM27001.1 - 0.019 15.5 0.0 0.046 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EWM27001.1 - 0.039 14.3 0.0 0.076 13.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 EWM27001.1 - 0.071 12.3 0.0 0.18 11.0 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain TIP49 PF06068.13 EWM27001.1 - 0.15 11.3 0.1 0.28 10.3 0.1 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain SKI PF01202.22 EWM27001.1 - 0.21 11.7 1.9 0.23 11.6 0.1 2.0 2 0 0 2 2 2 0 Shikimate kinase PALP PF00291.25 EWM27002.1 - 7.8e-62 209.3 0.9 7.8e-62 209.3 0.9 1.5 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 EWM27002.1 - 0.007 16.4 0.5 0.065 13.2 0.3 2.5 1 1 1 2 2 2 1 Zinc-binding dehydrogenase zf-GRF PF06839.12 EWM27003.1 - 3.2e-17 62.3 3.4 4.4e-17 61.9 1.2 2.4 2 0 0 2 2 2 1 GRF zinc finger zf-C4_Topoisom PF01396.19 EWM27003.1 - 0.035 13.9 1.6 0.035 13.9 1.6 5.3 6 0 0 6 6 6 0 Topoisomerase DNA binding C4 zinc finger Zn_ribbon_SprT PF17283.2 EWM27003.1 - 2.2 8.3 9.5 4.6 7.2 0.4 4.2 4 0 0 4 4 4 0 SprT-like zinc ribbon domain NUDIX PF00293.28 EWM27004.1 - 2e-11 44.1 0.0 2.7e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF4916 PF16262.5 EWM27004.1 - 5.2e-05 22.8 0.0 0.00062 19.3 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4916) CPSase_L_D2 PF02786.17 EWM27005.1 - 5.6e-73 244.9 0.3 1.1e-72 244.0 0.1 1.6 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EWM27005.1 - 1.7e-44 150.9 0.1 3.1e-43 146.8 0.1 2.5 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EWM27005.1 - 1.2e-34 118.6 0.0 3.1e-34 117.3 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EWM27005.1 - 1.2e-14 53.9 0.2 3e-14 52.6 0.2 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme PCC_BT PF18140.1 EWM27005.1 - 3.2e-12 46.9 0.0 2.3e-11 44.1 0.0 2.4 2 1 0 2 2 2 1 Propionyl-coenzyme A carboxylase BT domain ATP-grasp PF02222.22 EWM27005.1 - 3.4e-10 39.8 0.1 7.8e-10 38.6 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EWM27005.1 - 2.2e-09 37.1 0.1 6.3e-09 35.7 0.1 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 EWM27005.1 - 0.00032 20.8 0.2 0.00085 19.4 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 EWM27005.1 - 0.00068 19.5 0.1 0.0013 18.5 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 EWM27005.1 - 0.00097 18.5 0.0 0.0064 15.8 0.0 2.0 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp RimK PF08443.11 EWM27005.1 - 0.0022 17.6 0.0 0.0067 16.0 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain Biotin_lipoyl_2 PF13533.6 EWM27005.1 - 0.0029 17.4 0.0 0.007 16.2 0.0 1.6 1 0 0 1 1 1 1 Biotin-lipoyl like ATP-grasp_5 PF13549.6 EWM27005.1 - 0.045 13.2 0.0 0.09 12.2 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Peptidase_M16_C PF05193.21 EWM27006.1 - 3.2e-44 151.1 0.0 2.4e-20 73.3 0.0 3.7 3 1 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EWM27006.1 - 5.7e-16 58.8 0.0 1.3e-15 57.6 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) zf-MYND PF01753.18 EWM27007.1 - 2e-07 31.0 9.4 3.8e-07 30.1 9.4 1.5 1 0 0 1 1 1 1 MYND finger EamA PF00892.20 EWM27008.1 - 2.9e-12 46.9 32.3 1.3e-07 31.9 8.5 2.3 2 0 0 2 2 2 2 EamA-like transporter family EMP70 PF02990.16 EWM27009.1 - 2e-201 670.2 10.7 2.4e-201 669.9 10.7 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Fe-ADH PF00465.19 EWM27010.1 - 1.2e-67 228.3 0.0 1.6e-67 227.9 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EWM27010.1 - 4.4e-12 46.2 0.8 6.6e-06 26.0 0.4 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Ras PF00071.22 EWM27011.1 - 1e-38 132.5 0.0 1.5e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EWM27011.1 - 6.2e-26 91.0 0.0 1.1e-25 90.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EWM27011.1 - 9e-12 44.8 0.0 1.5e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EWM27011.1 - 3.8e-05 23.1 0.1 0.00025 20.5 0.0 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EWM27011.1 - 0.0002 20.8 0.0 0.00031 20.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EWM27011.1 - 0.00024 21.2 0.0 0.00047 20.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EWM27011.1 - 0.0029 17.2 0.0 0.0089 15.6 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 EWM27011.1 - 0.025 13.7 0.0 0.26 10.4 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.6 EWM27011.1 - 0.051 13.9 0.0 0.086 13.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 EWM27011.1 - 0.065 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Xan_ur_permease PF00860.20 EWM27012.1 - 3.5e-20 72.1 25.0 1.6e-13 50.2 8.8 2.3 2 0 0 2 2 2 2 Permease family BenE PF03594.13 EWM27012.1 - 4.9e-05 22.3 3.8 4.9e-05 22.3 3.8 3.0 3 1 0 3 3 3 1 Benzoate membrane transport protein Sulfate_transp PF00916.20 EWM27012.1 - 0.00017 20.5 4.5 0.00017 20.5 4.5 3.2 2 1 1 3 3 3 1 Sulfate permease family ABC2_membrane PF01061.24 EWM27013.1 - 3.2e-25 88.8 23.7 3.2e-25 88.8 23.7 1.9 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.27 EWM27013.1 - 1.2e-23 84.2 0.0 1.8e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EWM27013.1 - 3e-05 24.0 0.0 0.013 15.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EWM27013.1 - 0.00025 20.7 0.1 0.00067 19.4 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EWM27013.1 - 0.0016 19.0 0.1 0.0026 18.3 0.1 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EWM27013.1 - 0.0016 18.3 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EWM27013.1 - 0.0035 17.7 0.0 0.0059 17.0 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 EWM27013.1 - 0.0063 16.1 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EWM27013.1 - 0.0082 16.4 0.0 0.024 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 EWM27013.1 - 0.0094 15.4 0.0 0.02 14.3 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RNA_helicase PF00910.22 EWM27013.1 - 0.1 13.0 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 EWM27013.1 - 0.15 12.5 0.0 1.6 9.2 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 EWM27013.1 - 0.24 10.6 0.0 0.36 10.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain DUF4191 PF13829.6 EWM27013.1 - 1.4 8.2 2.9 3 7.1 2.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Topoisom_bac PF01131.20 EWM27014.1 - 5.1e-30 104.8 0.0 6.3e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 EWM27014.1 - 2.3e-16 59.9 0.0 3.7e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 EWM27014.1 - 0.012 16.0 0.0 0.021 15.3 0.0 1.4 1 0 0 1 1 1 0 Toprim domain Pox_T4_N PF04491.12 EWM27016.1 - 0.061 13.2 0.2 1.4 8.8 0.1 2.3 2 0 0 2 2 2 0 Poxvirus T4 protein, N terminus zf-CHCC PF10276.9 EWM27017.1 - 1.9e-13 50.2 1.0 2.6e-13 49.8 1.0 1.2 1 0 0 1 1 1 1 Zinc-finger domain DUF1479 PF07350.12 EWM27018.1 - 3.2e-05 22.9 0.0 0.0047 15.7 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF1479) PhyH PF05721.13 EWM27018.1 - 0.043 14.1 0.1 7.1 6.8 0.1 2.3 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Coq4 PF05019.13 EWM27019.1 - 3.4e-87 291.4 0.0 4.2e-87 291.1 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 UDPGP PF01704.18 EWM27020.1 - 4.5e-39 134.2 0.0 6.3e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 EWM27020.1 - 0.0099 16.2 0.5 0.039 14.3 0.1 2.3 2 1 0 2 2 2 1 MobA-like NTP transferase domain PP2C PF00481.21 EWM27021.1 - 1.6e-68 231.1 0.1 1.9e-68 230.9 0.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EWM27021.1 - 4.9e-07 29.6 0.2 8.9e-07 28.8 0.1 1.4 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.12 EWM27021.1 - 0.002 18.1 0.4 0.006 16.5 0.4 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 EWM27022.1 - 8.2e-57 192.8 0.1 1e-56 192.5 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EWM27022.1 - 0.0019 17.9 0.1 0.0031 17.2 0.1 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EWM27022.1 - 0.0042 17.0 0.2 0.011 15.7 0.2 1.8 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Surp PF01805.20 EWM27024.1 - 4.8e-15 55.3 0.0 1.1e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.22 EWM27024.1 - 2.8e-12 46.3 0.0 6.1e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 EWM27024.1 - 3e-06 27.9 0.0 6e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Hist_deacetyl PF00850.19 EWM27025.1 - 2.6e-64 217.6 0.0 5e-64 216.7 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain Ank_2 PF12796.7 EWM27025.1 - 3.1e-35 120.6 12.1 1.7e-13 51.0 0.3 4.5 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EWM27025.1 - 6.3e-22 77.7 5.6 4.2e-06 27.2 0.1 5.7 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EWM27025.1 - 1.3e-20 73.1 4.0 0.00098 19.4 0.1 6.1 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 EWM27025.1 - 2.7e-19 68.7 8.0 0.0036 17.7 0.1 6.8 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 EWM27025.1 - 6.9e-18 62.9 4.6 0.06 13.9 0.0 6.7 6 0 0 6 6 6 5 Ankyrin repeat BUD22 PF09073.10 EWM27025.1 - 0.83 8.9 10.6 1.6 8.0 10.6 1.3 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 EWM27025.1 - 1.6 8.0 12.1 2.8 7.3 12.1 1.3 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 EWM27025.1 - 2.5 6.1 23.7 3.7 5.5 23.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 EWM27025.1 - 3.6 7.3 10.6 6.7 6.4 10.6 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pox_Ag35 PF03286.14 EWM27025.1 - 9.3 6.0 9.0 20 4.9 9.0 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Chloroa_b-bind PF00504.21 EWM27030.1 - 1.2e-43 149.4 0.1 1.7e-43 148.9 0.1 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Pentapeptide PF00805.22 EWM27031.1 - 1.8e-13 49.9 4.3 2.5e-09 36.6 1.4 3.4 2 1 0 3 3 3 2 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 EWM27031.1 - 4.9e-11 42.7 1.3 5.1e-10 39.4 0.9 2.3 1 1 0 2 2 2 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 EWM27031.1 - 1.6e-08 34.5 1.8 3.2e-05 24.0 0.2 3.0 2 1 1 3 3 3 2 Pentapeptide repeats (9 copies) CTP_transf_1 PF01148.20 EWM27032.1 - 7.2e-48 163.7 2.4 8.5e-48 163.4 2.4 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Rhomboid PF01694.22 EWM27033.1 - 3.3e-20 72.6 18.9 8e-20 71.4 16.4 2.3 2 0 0 2 2 2 1 Rhomboid family DER1 PF04511.15 EWM27033.1 - 0.0012 18.8 13.4 0.0027 17.7 13.4 1.6 1 1 0 1 1 1 1 Der1-like family ATPase_gene1 PF09527.10 EWM27033.1 - 0.014 15.5 4.3 0.014 15.5 4.3 2.4 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter DUF1751 PF08551.10 EWM27033.1 - 0.024 15.2 7.7 0.024 15.2 7.7 2.1 2 1 1 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) PRKCSH-like PF12999.7 EWM27035.1 - 1.2e-47 161.9 1.2 3e-47 160.6 1.2 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 EWM27035.1 - 2.6e-27 95.4 0.1 2.6e-27 95.4 0.1 1.6 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 EWM27035.1 - 2.7e-05 25.1 0.6 2.7e-05 25.1 0.6 1.9 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein UPF0242 PF06785.11 EWM27035.1 - 0.0065 16.6 7.0 0.37 10.9 1.7 2.5 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0242) N-terminus FadA PF09403.10 EWM27035.1 - 0.19 12.3 0.1 0.19 12.3 0.1 3.0 3 1 0 3 3 3 0 Adhesion protein FadA Ldl_recept_a PF00057.18 EWM27035.1 - 0.47 10.7 12.4 0.093 13.0 1.5 2.6 1 1 1 2 2 2 0 Low-density lipoprotein receptor domain class A Roughex PF06020.11 EWM27036.1 - 0.035 13.2 8.5 0.051 12.7 8.5 1.2 1 0 0 1 1 1 0 Drosophila roughex protein CDC45 PF02724.14 EWM27036.1 - 0.05 11.9 0.1 0.058 11.7 0.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.9 EWM27036.1 - 0.053 12.4 2.2 0.066 12.1 2.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain FAM176 PF14851.6 EWM27036.1 - 0.79 9.4 6.6 19 4.9 6.5 2.2 2 0 0 2 2 2 0 FAM176 family DUF3446 PF11928.8 EWM27036.1 - 1.5 9.2 13.5 0.33 11.3 10.0 1.7 2 0 0 2 2 2 0 Early growth response N-terminal domain Presenilin PF01080.17 EWM27036.1 - 3.8 6.2 8.2 7.5 5.2 5.8 2.0 2 0 0 2 2 2 0 Presenilin DUF4834 PF16118.5 EWM27036.1 - 6 7.9 6.1 2.2e+02 2.9 6.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Pro_isomerase PF00160.21 EWM27037.1 - 1.5e-33 116.3 0.0 2e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPT PF03151.16 EWM27038.1 - 1.7e-24 86.7 14.8 2e-24 86.4 14.8 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 EWM27038.1 - 1.2e-05 24.7 18.4 1.5e-05 24.4 18.4 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EWM27038.1 - 0.0005 20.3 24.1 0.0018 18.5 11.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family PseudoU_synth_2 PF00849.22 EWM27039.1 - 1.1e-13 51.5 0.0 1.9e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 EWM27039.1 - 3.3e-06 26.7 0.6 8e-06 25.5 0.1 2.0 2 0 0 2 2 2 1 S4 domain UDG PF03167.19 EWM27040.1 - 9.9e-22 77.6 0.0 2.2e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Chloroa_b-bind PF00504.21 EWM27041.1 - 5.3e-32 111.6 0.1 7e-32 111.2 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein PEPCK_ATP PF01293.20 EWM27042.1 - 1.2e-184 614.4 0.0 1.4e-184 614.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase CBM_2 PF00553.19 EWM27042.1 - 0.17 12.2 0.5 1.9 8.9 0.0 2.4 2 0 0 2 2 2 0 Cellulose binding domain PEPCK_ATP PF01293.20 EWM27043.1 - 1.8e-219 729.2 0.0 2.1e-219 728.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase eIF2_C PF09173.11 EWM27044.1 - 3.6e-33 113.7 0.1 9.1e-33 112.4 0.1 1.8 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 EWM27044.1 - 7.4e-24 84.4 0.3 6.1e-23 81.4 0.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EWM27044.1 - 7.6e-14 51.9 2.5 2.3e-13 50.3 0.8 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EWM27044.1 - 0.0048 17.0 0.0 0.0094 16.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EWM27044.1 - 0.024 14.4 0.2 0.4 10.4 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 EWM27044.1 - 0.056 13.5 0.2 0.16 12.0 0.1 1.8 1 1 1 2 2 2 0 Dynamin family EamA PF00892.20 EWM27045.1 - 0.00014 22.1 8.5 0.00027 21.1 8.5 1.6 1 1 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 EWM27045.1 - 0.0024 17.9 0.4 0.0031 17.5 0.4 1.3 1 0 0 1 1 1 1 Putative transmembrane family 234 CRT-like PF08627.10 EWM27045.1 - 0.026 13.5 0.1 0.034 13.1 0.1 1.1 1 0 0 1 1 1 0 CRT-like, chloroquine-resistance transporter-like Phage_holin_3_6 PF07332.11 EWM27045.1 - 0.46 10.5 5.2 2.3 8.3 2.9 2.6 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III WD40 PF00400.32 EWM27047.1 - 1.9e-18 66.5 0.4 5e-06 27.2 0.0 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM27047.1 - 1.9e-06 28.1 0.0 0.068 13.5 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EWM27047.1 - 0.37 11.3 4.2 0.56 10.8 0.4 3.2 5 0 0 5 5 5 0 PQQ-like domain Acyltransferase PF01553.21 EWM27048.1 - 0.00055 19.6 0.0 0.00098 18.7 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Peptidase_M50 PF02163.22 EWM27049.1 - 7e-52 176.2 0.0 8.5e-52 175.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M50 PDZ_6 PF17820.1 EWM27049.1 - 1.7e-11 43.8 0.2 4e-11 42.6 0.2 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EWM27049.1 - 2.1e-10 40.8 0.0 4.8e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EWM27049.1 - 8.7e-05 22.8 0.0 0.00026 21.3 0.0 1.8 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EWM27049.1 - 0.042 13.8 0.1 0.12 12.4 0.1 1.8 1 0 0 1 1 1 0 Tricorn protease PDZ domain GRASP55_65 PF04495.14 EWM27049.1 - 0.18 12.1 0.0 0.33 11.3 0.0 1.3 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain Glyco_hydro_47 PF01532.20 EWM27051.1 - 1.5e-144 482.3 0.0 1.9e-144 482.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 HIRA_B PF09453.10 EWM27055.1 - 0.091 12.6 0.6 0.22 11.4 0.6 1.7 1 0 0 1 1 1 0 HIRA B motif SR-25 PF10500.9 EWM27055.1 - 0.25 10.9 6.9 0.62 9.6 6.9 1.7 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein dbPDZ_assoc PF16610.5 EWM27055.1 - 1.7 8.9 8.5 0.069 13.4 0.8 2.8 2 0 0 2 2 2 0 Unstructured region between two PDZ domains on Dlg5 NUDIX PF00293.28 EWM27059.1 - 9.8e-11 41.8 0.6 1.4e-10 41.3 0.6 1.2 1 0 0 1 1 1 1 NUDIX domain Spt20 PF12090.8 EWM27060.1 - 0.7 9.5 8.2 0.87 9.1 8.2 1.1 1 0 0 1 1 1 0 Spt20 family Pex14_N PF04695.13 EWM27060.1 - 9.6 6.8 13.4 13 6.4 13.4 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-4CXXC_R1 PF10497.9 EWM27061.1 - 3.4 8.0 11.6 0.13 12.5 4.4 2.3 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 VPS9 PF02204.18 EWM27062.1 - 5.4e-12 45.8 0.0 1.1e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PfkB PF00294.24 EWM27063.1 - 1.4e-40 139.5 0.0 4.2e-26 92.0 0.0 2.0 2 0 0 2 2 2 2 pfkB family carbohydrate kinase DUF2953 PF11167.8 EWM27063.1 - 0.15 12.2 0.1 0.33 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) Gln-synt_C PF00120.24 EWM27066.1 - 1.2e-14 54.0 0.0 4.9e-12 45.5 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EWM27066.1 - 8.3e-14 51.1 0.0 1.4e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Aminotran_5 PF00266.19 EWM27067.1 - 1.2e-146 488.4 0.0 1.4e-146 488.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EWM27067.1 - 2e-05 24.0 0.0 3.7e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EWM27067.1 - 3.2e-05 22.6 0.2 0.00024 19.8 0.0 2.0 1 1 1 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme DnaJ PF00226.31 EWM27069.1 - 5.6e-22 77.6 0.0 1.1e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.28 EWM27069.1 - 1e-17 63.1 20.1 9.2e-05 22.1 0.1 7.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 EWM27069.1 - 9.9e-14 50.3 34.4 0.0009 19.2 0.8 7.7 9 0 0 9 9 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 EWM27069.1 - 5.7e-09 35.5 0.1 8.4e-06 25.4 0.0 3.5 3 0 0 3 3 3 2 TPR repeat TPR_19 PF14559.6 EWM27069.1 - 3.4e-06 27.5 4.7 0.072 13.6 0.4 4.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EWM27069.1 - 0.0013 18.8 13.0 2.4 8.6 0.2 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 EWM27069.1 - 0.096 13.1 0.2 31 5.3 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EWM27069.1 - 0.13 12.3 5.6 2.3 8.3 0.1 4.0 4 0 0 4 4 4 0 Putative TPR-like repeat ANAPC3 PF12895.7 EWM27069.1 - 0.21 11.9 11.1 3.6 7.9 0.2 4.1 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EWM27069.1 - 0.45 10.7 8.5 18 5.6 0.2 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 EWM27069.1 - 0.73 10.0 13.0 0.21 11.7 0.3 4.8 3 2 1 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 EWM27069.1 - 4.3 8.1 24.6 0.61 10.8 0.3 5.7 6 1 1 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 EWM27069.1 - 5.9 7.8 7.7 1.5e+02 3.4 0.1 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EWM27069.1 - 6.7 7.1 27.6 0.22 11.9 1.1 6.5 6 2 2 8 8 8 0 Tetratricopeptide repeat TPR_16 PF13432.6 EWM27070.1 - 1.5e-18 67.2 54.6 6.5e-06 26.7 0.1 11.9 9 2 2 11 11 10 6 Tetratricopeptide repeat TPR_2 PF07719.17 EWM27070.1 - 3.9e-17 60.9 29.7 0.0078 16.2 0.0 12.8 14 0 0 14 14 12 5 Tetratricopeptide repeat TPR_1 PF00515.28 EWM27070.1 - 1.1e-15 56.7 7.3 0.06 13.2 0.0 9.9 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_8 PF13181.6 EWM27070.1 - 1.9e-13 49.4 2.5 0.14 12.4 0.0 8.2 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 EWM27070.1 - 3.6e-13 49.6 30.8 0.0084 16.4 0.3 9.3 6 3 5 11 11 11 7 Tetratricopeptide repeat TPR_19 PF14559.6 EWM27070.1 - 3.3e-10 40.3 35.6 0.037 14.5 0.0 10.4 10 1 1 11 11 10 5 Tetratricopeptide repeat TPR_11 PF13414.6 EWM27070.1 - 1.6e-09 37.3 6.6 0.25 11.1 0.0 7.9 9 0 0 9 9 9 3 TPR repeat TPR_6 PF13174.6 EWM27070.1 - 2.7e-09 37.0 17.2 2.4 9.0 0.0 10.5 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_14 PF13428.6 EWM27070.1 - 2.2e-06 28.0 66.2 0.12 13.3 0.8 14.6 10 4 7 17 17 13 4 Tetratricopeptide repeat TPR_9 PF13371.6 EWM27070.1 - 2.6e-06 27.5 26.9 0.25 11.5 1.5 6.5 6 0 0 6 6 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EWM27070.1 - 5.6e-06 26.5 13.2 0.5 10.6 0.0 6.5 4 3 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EWM27070.1 - 3.2e-05 24.0 2.0 54 4.5 0.0 8.6 10 0 0 10 10 8 0 Tetratricopeptide repeat NARP1 PF12569.8 EWM27070.1 - 0.0027 16.7 15.8 0.027 13.4 0.0 4.5 5 0 0 5 5 5 2 NMDA receptor-regulated protein 1 TPR_7 PF13176.6 EWM27070.1 - 0.0036 17.2 14.8 8.3 6.7 0.0 8.6 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_10 PF13374.6 EWM27070.1 - 0.019 14.8 23.1 0.4 10.6 0.1 8.1 9 0 0 9 9 9 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EWM27070.1 - 0.081 12.6 4.5 0.44 10.2 0.1 3.7 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) Macoilin PF09726.9 EWM27070.1 - 4.2 5.8 16.2 6.4 5.2 16.2 1.1 1 0 0 1 1 1 0 Macoilin family Golgin_A5 PF09787.9 EWM27070.1 - 5.7 6.3 14.9 11 5.3 14.9 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF2401 PF10287.9 EWM27074.1 - 0.045 13.3 0.1 0.063 12.9 0.1 1.1 1 0 0 1 1 1 0 Putative TOS1-like glycosyl hydrolase (DUF2401) Leader_Trp PF08255.11 EWM27074.1 - 0.25 11.4 0.3 0.25 11.4 0.3 2.0 2 0 0 2 2 2 0 Trp-operon Leader Peptide Ribosomal_S17 PF00366.20 EWM27075.1 - 8.2e-23 80.3 1.0 1.2e-22 79.7 1.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 FAD_binding_3 PF01494.19 EWM27076.1 - 6.7e-19 68.3 0.3 1.6e-18 67.1 0.3 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EWM27076.1 - 7.3e-05 22.1 0.7 0.0041 16.4 0.1 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EWM27076.1 - 8.9e-05 22.7 0.1 0.00023 21.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF1980 PF09323.10 EWM27076.1 - 0.02 14.8 0.8 0.38 10.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Pyr_redox PF00070.27 EWM27076.1 - 0.066 13.8 0.0 1.5 9.4 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase C4bp_oligo PF18453.1 EWM27076.1 - 0.076 13.2 0.0 6.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Oligomerization domain of C4b-binding protein alpha AFG1_ATPase PF03969.16 EWM27077.1 - 1.2e-88 297.5 0.1 6e-57 193.2 0.1 3.7 2 1 1 3 3 3 3 AFG1-like ATPase AAA_16 PF13191.6 EWM27077.1 - 4.8e-06 27.1 0.3 4.8e-06 27.1 0.3 2.7 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EWM27077.1 - 0.00096 19.4 0.0 0.0021 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EWM27077.1 - 0.021 15.3 0.0 0.062 13.7 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 EWM27077.1 - 0.051 12.8 0.0 0.15 11.3 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 EWM27077.1 - 0.14 12.1 0.3 0.87 9.6 0.1 2.5 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) TFIIA PF03153.13 EWM27078.1 - 0.039 14.0 12.0 0.038 14.0 12.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PhoR PF11808.8 EWM27078.1 - 0.064 13.7 1.2 0.11 12.9 1.2 1.4 1 0 0 1 1 1 0 Phosphate regulon sensor protein PhoR DUF4336 PF14234.6 EWM27079.1 - 3.7e-83 279.3 0.0 9.3e-69 232.0 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4336) TP_methylase PF00590.20 EWM27080.1 - 4.5e-27 95.4 0.4 6.9e-27 94.8 0.4 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Zn_clus PF00172.18 EWM27081.1 - 1.6e-07 31.3 10.0 1.6e-07 31.3 10.0 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 EWM27082.1 - 1.6e-32 112.9 0.0 2.1e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM27082.1 - 7e-13 48.5 0.0 1e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EWM27082.1 - 0.0085 16.0 0.0 0.078 12.9 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family tRNA-synt_His PF13393.6 EWM27083.1 - 4.3e-45 154.3 0.0 6.3e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EWM27083.1 - 4.7e-13 49.1 0.0 8.2e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EWM27083.1 - 3.3e-08 33.7 0.0 6.3e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 EWM27083.1 - 0.015 14.8 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) tRNA-synt_His PF13393.6 EWM27084.1 - 4.3e-45 154.3 0.0 6.4e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EWM27084.1 - 4.9e-13 49.0 0.0 8.3e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EWM27084.1 - 3.3e-08 33.7 0.0 6.3e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 EWM27084.1 - 0.015 14.8 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) ABC_tran PF00005.27 EWM27085.1 - 5.4e-50 169.5 0.1 1.3e-26 93.7 0.0 3.1 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 EWM27085.1 - 2.6e-21 76.7 0.2 9.5e-06 25.6 0.0 4.2 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_CTD PF16326.5 EWM27085.1 - 1e-10 41.7 6.1 1e-10 41.7 6.1 3.3 3 1 1 4 4 4 1 ABC transporter C-terminal domain SMC_N PF02463.19 EWM27085.1 - 4.3e-10 39.4 0.8 0.0055 16.2 0.1 4.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_tran_Xtn PF12848.7 EWM27085.1 - 4.9e-10 39.3 11.7 8.7e-10 38.5 4.7 3.4 3 0 0 3 3 3 1 ABC transporter RsgA_GTPase PF03193.16 EWM27085.1 - 3e-06 27.2 0.8 0.09 12.7 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 EWM27085.1 - 4e-06 27.1 0.1 0.0052 16.9 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EWM27085.1 - 8.9e-06 26.3 14.7 0.048 14.2 0.0 4.2 3 1 1 4 4 4 2 AAA domain AAA_29 PF13555.6 EWM27085.1 - 1.3e-05 24.8 2.6 0.054 13.2 0.1 2.9 3 0 0 3 3 3 2 P-loop containing region of AAA domain MeaB PF03308.16 EWM27085.1 - 1.7e-05 23.9 0.1 0.057 12.4 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 EWM27085.1 - 2e-05 24.6 0.2 0.16 12.1 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.6 EWM27085.1 - 0.00059 19.7 3.9 0.83 9.3 0.1 3.4 4 0 0 4 4 3 2 AAA ATPase domain AAA_22 PF13401.6 EWM27085.1 - 0.0016 18.7 3.6 25 5.1 0.0 4.3 4 0 0 4 4 4 0 AAA domain AAA_16 PF13191.6 EWM27085.1 - 0.0044 17.4 10.7 0.15 12.4 0.0 3.8 3 1 1 4 4 4 2 AAA ATPase domain AAA_27 PF13514.6 EWM27085.1 - 0.0052 16.4 2.2 2.7 7.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 EWM27085.1 - 0.0059 16.5 0.1 1.9 8.4 0.0 2.6 2 0 0 2 2 2 1 NACHT domain ATP-synt_ab PF00006.25 EWM27085.1 - 0.007 16.1 0.0 0.53 9.9 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.6 EWM27085.1 - 0.0084 16.7 0.1 5.4 7.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EWM27085.1 - 0.014 15.1 5.1 1.4 8.6 0.0 3.1 4 0 0 4 4 3 0 AAA domain AAA PF00004.29 EWM27085.1 - 0.015 15.7 0.5 19 5.7 0.1 3.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EWM27085.1 - 0.043 13.3 0.1 9.8 5.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 EWM27085.1 - 0.068 12.7 0.3 15 5.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.15 EWM27085.1 - 0.14 12.1 0.1 14 5.6 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_14 PF13173.6 EWM27085.1 - 0.15 12.1 0.8 24 5.0 0.2 3.3 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 EWM27085.1 - 0.15 11.2 3.5 3 7.0 1.3 3.0 2 1 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 EWM27085.1 - 0.23 11.9 0.3 13 6.2 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.23 EWM27085.1 - 0.35 10.9 7.3 1.2 9.1 0.2 3.0 4 0 0 4 4 2 0 Dynamin family DUF87 PF01935.17 EWM27085.1 - 0.41 10.7 2.5 2.5 8.1 0.0 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain cobW PF02492.19 EWM27085.1 - 0.91 9.1 2.3 12 5.4 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Peptidase_S41 PF03572.18 EWM27086.1 - 1e-44 152.1 1.1 1.6e-44 151.4 1.1 1.3 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 EWM27086.1 - 7.6e-12 44.9 0.2 1.6e-11 43.9 0.2 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EWM27086.1 - 1.5e-09 38.1 0.0 3.2e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EWM27086.1 - 8.7e-07 29.2 0.2 2e-06 28.0 0.2 1.6 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EWM27086.1 - 0.0038 17.2 0.2 0.014 15.3 0.1 2.0 2 0 0 2 2 2 1 Tricorn protease PDZ domain Tricorn_C1 PF14684.6 EWM27086.1 - 0.027 14.5 0.3 0.049 13.7 0.3 1.3 1 0 0 1 1 1 0 Tricorn protease C1 domain Frataxin_Cyay PF01491.16 EWM27088.1 - 4.5e-31 107.1 0.0 9.9e-31 106.0 0.0 1.5 2 0 0 2 2 2 1 Frataxin-like domain ABC2_membrane PF01061.24 EWM27089.1 - 1.5e-22 80.0 24.1 1.5e-22 80.0 24.1 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 EWM27089.1 - 6.8e-20 72.0 0.0 1e-19 71.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EWM27089.1 - 0.00016 21.6 0.0 0.065 13.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EWM27089.1 - 0.0013 19.3 0.1 0.002 18.7 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EWM27089.1 - 0.0024 18.2 0.1 0.0039 17.6 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EWM27089.1 - 0.0031 17.4 0.0 0.0051 16.7 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_28 PF13521.6 EWM27089.1 - 0.0083 16.4 0.1 0.014 15.6 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EWM27089.1 - 0.01 15.6 0.3 0.024 14.4 0.3 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EWM27089.1 - 0.027 14.7 0.1 0.055 13.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EWM27089.1 - 0.048 13.2 0.1 0.097 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 EWM27089.1 - 0.078 12.4 0.0 4.5 6.7 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain cobW PF02492.19 EWM27089.1 - 0.21 11.2 0.0 0.33 10.5 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF1242 PF06842.12 EWM27090.1 - 9e-12 44.6 0.3 1.8e-11 43.6 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) OMPdecase PF00215.24 EWM27091.1 - 8.2e-27 94.2 0.0 1.7e-26 93.3 0.0 1.5 1 1 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.27 EWM27091.1 - 9.5e-19 67.5 0.1 2e-18 66.4 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain ThiG PF05690.14 EWM27091.1 - 0.013 14.8 0.4 0.48 9.7 0.2 2.4 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG E2F_CC-MB PF16421.5 EWM27092.1 - 6.1e-27 93.8 0.1 8.8e-27 93.3 0.1 1.2 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.20 EWM27092.1 - 2.2e-23 82.1 0.1 3.8e-23 81.3 0.1 1.4 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain UPF0242 PF06785.11 EWM27092.1 - 0.016 15.3 0.6 0.023 14.8 0.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4423 PF14394.6 EWM27092.1 - 0.071 12.8 0.5 0.1 12.3 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) B-block_TFIIIC PF04182.12 EWM27092.1 - 0.13 12.4 0.0 0.36 11.0 0.0 1.8 1 1 0 1 1 1 0 B-block binding subunit of TFIIIC ASH PF15780.5 EWM27093.1 - 9.9e-07 28.9 0.0 0.00011 22.4 0.0 2.7 2 0 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 EWM27093.1 - 0.05 13.9 0.0 0.3 11.3 0.0 2.3 3 0 0 3 3 3 0 Transmembrane protein 131-like CBF PF03914.17 EWM27094.1 - 6.5e-35 120.7 0.0 3.3e-34 118.4 0.0 2.3 2 0 0 2 2 2 1 CBF/Mak21 family Adaptin_N PF01602.20 EWM27094.1 - 0.032 12.8 0.0 0.087 11.4 0.0 1.6 2 0 0 2 2 2 0 Adaptin N terminal region Cnd1 PF12717.7 EWM27094.1 - 0.17 11.9 0.1 0.42 10.6 0.0 1.6 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 SUIM_assoc PF16619.5 EWM27094.1 - 8.6 6.5 12.3 26 5.0 12.3 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Acyl_transf_1 PF00698.21 EWM27095.1 - 2.8e-27 96.1 0.4 3.4e-27 95.8 0.4 1.1 1 0 0 1 1 1 1 Acyl transferase domain SQS_PSY PF00494.19 EWM27096.1 - 8.4e-55 186.1 2.2 9.6e-55 185.9 2.2 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase DNA_ligase_A_N PF04675.14 EWM27097.1 - 1.6e-27 97.0 0.0 2.2e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.21 EWM27097.1 - 1.9e-19 70.1 0.0 1.2e-18 67.5 0.0 2.1 2 0 0 2 2 2 1 ATP dependent DNA ligase domain Lipase_3 PF01764.25 EWM27098.1 - 6.4e-17 61.7 0.1 1.3e-16 60.8 0.1 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EWM27098.1 - 0.034 14.7 0.4 0.034 14.7 0.4 2.4 1 1 0 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EWM27098.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 EWM27098.1 - 0.13 11.8 0.0 2.1 7.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) PGAP1 PF07819.13 EWM27098.1 - 0.2 11.4 0.0 0.32 10.7 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DAO PF01266.24 EWM27099.1 - 8.4e-25 88.1 2.2 1e-24 87.8 2.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EWM27099.1 - 8.2e-05 22.8 0.0 0.00021 21.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 EWM27099.1 - 0.00024 20.4 0.0 0.00037 19.8 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 EWM27099.1 - 0.00032 20.0 0.0 0.014 14.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EWM27099.1 - 0.0023 17.1 0.1 0.0041 16.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EWM27099.1 - 0.015 15.8 0.0 0.032 14.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EWM27099.1 - 0.017 15.1 0.1 0.07 13.1 0.1 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 EWM27099.1 - 0.18 10.9 0.2 0.29 10.2 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A MT0933_antitox PF14013.6 EWM27100.1 - 0.0036 17.6 0.5 0.51 10.7 0.1 2.9 1 1 1 2 2 2 2 MT0933-like antitoxin protein Apolipoprotein PF01442.18 EWM27100.1 - 0.013 15.4 0.3 0.019 14.8 0.3 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 EWM27100.1 - 0.05 13.7 0.0 1 9.5 0.0 2.1 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF2277 PF10041.9 EWM27100.1 - 0.2 12.0 0.1 0.2 12.0 0.1 1.9 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2277) MT0933_antitox PF14013.6 EWM27101.1 - 0.0038 17.5 0.6 0.52 10.7 0.1 2.9 1 1 1 2 2 2 1 MT0933-like antitoxin protein Apolipoprotein PF01442.18 EWM27101.1 - 0.014 15.3 0.4 0.021 14.7 0.4 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 EWM27101.1 - 0.049 13.7 0.0 1 9.4 0.0 2.2 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF4592 PF15262.6 EWM27101.1 - 0.17 12.5 0.6 0.3 11.8 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4592) DUF2277 PF10041.9 EWM27101.1 - 0.2 12.0 0.1 0.2 12.0 0.1 1.9 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2277) LETM1 PF07766.13 EWM27102.1 - 2.7e-24 86.0 0.0 3.8e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 LETM1-like protein Ion_trans PF00520.31 EWM27103.1 - 6.7e-29 100.8 10.1 8.8e-29 100.4 10.1 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EWM27103.1 - 4.3e-05 23.4 7.7 0.00014 21.7 7.7 2.0 1 1 0 1 1 1 1 Ion channel HR1 PF02185.16 EWM27103.1 - 0.037 14.1 1.9 1.3 9.2 0.2 2.5 2 0 0 2 2 2 0 Hr1 repeat GEMIN8 PF15348.6 EWM27103.1 - 0.31 11.3 6.8 0.058 13.7 3.4 1.4 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 ABC1 PF03109.16 EWM27104.1 - 3.7e-33 114.2 0.0 7e-33 113.3 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EWM27104.1 - 0.044 13.7 5.0 0.075 12.9 0.8 3.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 EWM27104.1 - 0.13 11.9 0.0 0.45 10.1 0.0 1.8 2 0 0 2 2 2 0 RIO1 family zf-C2H2 PF00096.26 EWM27105.1 - 1.4e-20 72.5 17.5 5.3e-05 23.4 0.1 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EWM27105.1 - 7.1e-15 54.7 23.5 2e-05 24.8 0.6 6.2 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EWM27105.1 - 1.2e-12 47.5 23.8 0.0097 16.7 0.2 5.6 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EWM27105.1 - 1.7e-09 37.7 1.2 0.25 11.7 0.0 4.8 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EWM27105.1 - 1.1e-06 28.8 5.0 0.0038 17.6 0.1 4.5 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 EWM27105.1 - 0.00039 20.1 10.1 0.087 12.6 1.5 4.5 4 0 0 4 4 4 2 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 EWM27105.1 - 0.016 14.9 1.1 0.016 14.9 1.1 4.7 5 0 0 5 5 4 0 zinc-finger C2H2-type FOXP-CC PF16159.5 EWM27105.1 - 0.066 13.9 5.8 0.88 10.2 0.2 3.8 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 EWM27105.1 - 0.071 13.1 17.7 0.55 10.3 0.0 5.4 5 0 0 5 5 5 0 C2H2-type zinc finger zf_ZIC PF18366.1 EWM27105.1 - 0.21 11.7 2.0 33 4.7 0.0 3.9 4 0 0 4 4 4 0 Zic proteins zinc finger domain zf-C2HE PF16278.5 EWM27105.1 - 0.25 11.8 6.4 0.44 11.0 0.2 3.8 3 1 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-LYAR PF08790.11 EWM27105.1 - 0.82 9.6 6.7 2.1 8.3 0.4 3.7 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf-BED PF02892.15 EWM27105.1 - 1 9.4 5.9 3.1 7.9 0.7 3.3 2 1 1 3 3 3 0 BED zinc finger CRAL_TRIO PF00650.20 EWM27106.1 - 7.6e-15 55.0 0.0 1.1e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EWM27106.1 - 0.00042 20.5 0.0 0.00073 19.7 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain TP_methylase PF00590.20 EWM27107.1 - 3.4e-22 79.4 0.1 8.2e-22 78.2 0.1 1.6 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Tim17 PF02466.19 EWM27108.1 - 5.3e-08 33.2 4.8 6.7e-08 32.9 4.8 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TMEM126 PF07114.11 EWM27108.1 - 0.039 13.3 0.0 0.074 12.4 0.0 1.6 1 1 0 1 1 1 0 Transmembrane protein 126 WES_acyltransf PF03007.16 EWM27108.1 - 0.32 10.7 1.1 0.96 9.2 0.8 1.7 2 0 0 2 2 2 0 Wax ester synthase-like Acyl-CoA acyltransferase domain PhyH PF05721.13 EWM27109.1 - 5.4e-25 88.9 0.0 6.9e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DTW PF03942.15 EWM27110.1 - 1.2e-11 44.8 0.0 1.6e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 DTW domain RRM_1 PF00076.22 EWM27111.1 - 1.6e-10 40.6 0.0 0.00068 19.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1356 PF07092.12 EWM27112.1 - 0.18 11.0 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) DUF1356 PF07092.12 EWM27113.1 - 0.18 11.0 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) Ebp2 PF05890.12 EWM27114.1 - 7.3e-69 232.3 6.7 1.2e-68 231.6 6.7 1.3 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Actin PF00022.19 EWM27115.1 - 9.9e-35 119.9 0.0 4.6e-14 51.8 0.0 4.0 4 0 0 4 4 4 4 Actin DUF760 PF05542.11 EWM27116.1 - 7.1e-20 71.2 0.4 1.4e-10 41.3 0.2 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF760) Form_Nir_trans PF01226.17 EWM27117.1 - 8.9e-63 211.8 25.7 1.1e-62 211.5 25.7 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter 3Beta_HSD PF01073.19 EWM27119.1 - 7.4e-63 212.2 0.0 9.3e-63 211.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EWM27119.1 - 2.8e-35 121.9 0.1 4e-35 121.4 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EWM27119.1 - 7.6e-19 68.3 0.1 1.3e-17 64.2 0.1 2.4 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EWM27119.1 - 7.1e-18 65.2 0.5 7.1e-18 65.2 0.5 1.5 2 0 0 2 2 2 1 NAD(P)H-binding Cyt-b5 PF00173.28 EWM27119.1 - 8.7e-17 61.0 0.3 8.1e-16 57.9 0.1 2.4 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_4 PF07993.12 EWM27119.1 - 1.5e-14 53.8 1.6 6.1e-11 42.0 0.1 2.4 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 EWM27119.1 - 1.5e-11 43.9 0.1 1.9e-11 43.6 0.1 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EWM27119.1 - 4.2e-07 29.4 3.2 1.9e-06 27.2 3.2 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 EWM27119.1 - 0.00023 20.8 2.2 0.00039 20.0 2.2 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 EWM27119.1 - 0.0021 18.0 0.2 1.7 8.5 0.0 2.3 2 0 0 2 2 2 2 KR domain adh_short PF00106.25 EWM27119.1 - 0.044 13.2 0.3 0.083 12.3 0.2 1.4 1 1 0 1 1 1 0 short chain dehydrogenase NAD_binding_7 PF13241.6 EWM27119.1 - 0.085 13.3 0.1 0.16 12.4 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding KIND PF16474.5 EWM27119.1 - 0.091 12.7 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain CoA_binding_2 PF13380.6 EWM27119.1 - 0.11 13.0 0.4 0.39 11.2 0.4 2.0 1 1 0 1 1 1 0 CoA binding domain DUF3176 PF11374.8 EWM27120.1 - 0.015 15.5 0.6 1.1 9.5 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3176) Cupin_8 PF13621.6 EWM27124.1 - 1.5e-17 64.2 0.2 4e-17 62.8 0.2 1.6 1 1 0 1 1 1 1 Cupin-like domain Sulfotransfer_3 PF13469.6 EWM27124.1 - 3.2e-05 24.4 0.0 0.0044 17.4 0.0 2.9 1 1 1 2 2 2 2 Sulfotransferase family Peptidase_S8 PF00082.22 EWM27126.1 - 6.7e-23 81.4 0.1 1.5e-22 80.2 0.1 1.5 1 0 0 1 1 1 1 Subtilase family MT-A70 PF05063.14 EWM27127.1 - 5.9e-40 137.0 0.0 1.3e-39 135.9 0.0 1.6 1 0 0 1 1 1 1 MT-A70 Cons_hypoth95 PF03602.15 EWM27127.1 - 0.041 13.5 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein 95 LSM PF01423.22 EWM27128.1 - 1.4e-21 76.0 0.5 1.9e-21 75.5 0.5 1.2 1 0 0 1 1 1 1 LSM domain CFEM PF05730.11 EWM27129.1 - 0.01 15.9 1.6 0.053 13.6 1.6 2.3 1 0 0 1 1 1 0 CFEM domain DUF829 PF05705.14 EWM27130.1 - 2.9e-30 105.9 0.1 6.8e-30 104.7 0.1 1.6 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Aminotran_3 PF00202.21 EWM27131.1 - 6.5e-117 390.6 0.0 7.6e-117 390.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 EWM27131.1 - 0.077 12.3 0.0 0.19 11.0 0.0 1.7 1 1 0 1 1 1 0 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EWM27131.1 - 0.18 11.0 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Tyrosinase PF00264.20 EWM27132.1 - 4.5e-31 108.9 12.0 2.2e-17 64.1 0.2 2.8 2 1 1 3 3 3 2 Common central domain of tyrosinase CBM_1 PF00734.18 EWM27132.1 - 1.9e-07 30.9 13.7 4e-07 29.9 13.7 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain ALAD PF00490.21 EWM27133.1 - 2.9e-137 457.1 0.0 3.5e-137 456.8 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase EF1_GNE PF00736.19 EWM27134.1 - 1.4e-27 95.6 1.4 2.2e-27 95.0 1.4 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain Stm1_N PF09598.10 EWM27134.1 - 0.05 14.5 1.5 0.05 14.5 1.5 1.7 2 0 0 2 2 2 0 Stm1 UBA2_C PF16195.5 EWM27134.1 - 0.08 13.6 7.3 0.15 12.8 7.3 1.4 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus TRPM_tetra PF16519.5 EWM27134.1 - 2.9 8.0 5.0 0.41 10.8 0.9 1.6 2 0 0 2 2 2 0 Tetramerisation domain of TRPM AAA PF00004.29 EWM27136.1 - 1.8e-42 144.9 0.0 3.3e-42 144.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EWM27136.1 - 1.5e-11 43.9 0.1 3e-11 42.9 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EWM27136.1 - 2.8e-06 27.8 0.2 0.00072 20.0 0.1 2.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EWM27136.1 - 8.3e-05 22.9 0.2 0.0036 17.6 0.2 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EWM27136.1 - 0.00044 20.0 0.0 0.0014 18.4 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EWM27136.1 - 0.0006 20.1 0.0 0.0011 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 EWM27136.1 - 0.00061 19.1 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 EWM27136.1 - 0.0017 18.5 0.0 0.0034 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EWM27136.1 - 0.0017 18.3 0.2 0.048 13.6 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 EWM27136.1 - 0.0072 15.5 0.0 0.019 14.1 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF815) TsaE PF02367.17 EWM27136.1 - 0.0098 15.9 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EWM27136.1 - 0.012 16.2 0.0 0.033 14.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.12 EWM27136.1 - 0.014 14.7 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.6 EWM27136.1 - 0.023 14.9 0.0 0.053 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EWM27136.1 - 0.032 13.9 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 EWM27136.1 - 0.072 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 EWM27136.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FtsH_ext PF06480.15 EWM27136.1 - 0.12 12.7 0.0 0.38 11.1 0.0 1.9 2 0 0 2 2 2 0 FtsH Extracellular AAA_3 PF07726.11 EWM27136.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EWM27136.1 - 0.15 11.9 0.1 0.49 10.3 0.0 1.8 1 1 0 2 2 2 0 NACHT domain Sugar_tr PF00083.24 EWM27139.1 - 1.9e-100 336.9 20.8 2.3e-100 336.6 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EWM27139.1 - 2.7e-34 118.6 28.2 6.1e-31 107.6 28.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LtrA PF06772.11 EWM27139.1 - 0.00028 20.2 11.6 0.00028 20.2 11.6 2.0 2 1 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) Ald_Xan_dh_C2 PF02738.18 EWM27140.1 - 8.2e-143 476.8 0.0 1.2e-142 476.2 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Fer2_2 PF01799.20 EWM27140.1 - 4.3e-24 84.3 0.3 1.1e-23 83.0 0.3 1.8 1 0 0 1 1 1 1 [2Fe-2S] binding domain FAD_binding_5 PF00941.21 EWM27140.1 - 1.7e-17 63.7 0.0 1.4e-16 60.7 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 EWM27140.1 - 2e-17 63.5 0.0 5.2e-17 62.2 0.0 1.8 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain FAD_binding_3 PF01494.19 EWM27140.1 - 5.1e-16 58.9 0.0 6.8e-08 32.1 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain CO_deh_flav_C PF03450.17 EWM27140.1 - 1.6e-10 41.1 1.5 1.6e-10 41.1 1.5 3.5 3 1 0 3 3 3 1 CO dehydrogenase flavoprotein C-terminal domain FAD_binding_2 PF00890.24 EWM27140.1 - 0.24 10.5 3.7 0.49 9.4 3.7 1.5 1 0 0 1 1 1 0 FAD binding domain Fer2 PF00111.27 EWM27140.1 - 0.31 11.0 2.3 0.92 9.5 2.3 1.8 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain NAD_binding_8 PF13450.6 EWM27140.1 - 0.32 11.2 2.5 1.1 9.5 2.5 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Cnn_1N PF07989.11 EWM27141.1 - 7 6.9 11.0 1.5 9.1 2.5 3.1 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 NTF2 PF02136.20 EWM27142.1 - 1.4e-23 83.8 0.0 1.5e-23 83.6 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Sec7 PF01369.20 EWM27144.1 - 7.5e-70 234.3 0.0 1.6e-69 233.3 0.0 1.6 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EWM27144.1 - 3.1e-42 144.2 1.6 3.1e-42 144.2 1.6 4.0 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 EWM27144.1 - 6.6e-34 117.1 1.6 3.4e-33 114.8 0.1 2.8 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF1981 PF09324.10 EWM27144.1 - 2.4e-32 110.6 0.3 4.3e-30 103.4 0.1 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) Mon2_C PF16206.5 EWM27144.1 - 0.017 13.3 0.0 0.048 11.8 0.1 1.6 2 0 0 2 2 2 0 C-terminal region of Mon2 protein B56 PF01603.20 EWM27144.1 - 0.12 11.3 6.0 0.19 10.6 0.8 2.3 2 0 0 2 2 2 0 Protein phosphatase 2A regulatory B subunit (B56 family) PH PF00169.29 EWM27145.1 - 7.4e-18 65.0 0.2 8.9e-18 64.7 0.2 1.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EWM27145.1 - 4e-07 30.4 3.8 6.5e-06 26.5 3.8 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 EWM27145.1 - 0.00095 19.2 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 EWM27145.1 - 0.0026 18.0 0.1 0.004 17.4 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 EWM27145.1 - 0.019 15.3 0.2 0.25 11.7 0.2 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain YL1_C PF08265.11 EWM27145.1 - 0.08 12.7 0.3 0.16 11.8 0.1 1.6 2 0 0 2 2 2 0 YL1 nuclear protein C-terminal domain PH_6 PF15406.6 EWM27145.1 - 0.098 12.9 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain Ribonuclease_3 PF00636.26 EWM27146.1 - 5.2e-29 101.0 0.0 2.6e-13 50.5 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EWM27146.1 - 1.7e-21 76.7 0.0 1e-09 38.6 0.0 3.4 3 1 0 3 3 3 2 Ribonuclease-III-like DEAD PF00270.29 EWM27146.1 - 7.5e-15 55.1 0.0 1.3e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EWM27146.1 - 8e-15 55.1 0.0 2.2e-14 53.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EWM27146.1 - 1.9e-09 37.7 0.0 4e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Dicer_dimer PF03368.14 EWM27146.1 - 2.1e-08 34.2 0.0 1.1e-07 31.8 0.0 2.2 2 0 0 2 2 2 1 Dicer dimerisation domain IstB_IS21 PF01695.17 EWM27146.1 - 3.8e-05 23.5 0.2 0.00015 21.6 0.0 2.0 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_22 PF13401.6 EWM27146.1 - 0.002 18.4 0.1 0.0057 16.9 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EWM27146.1 - 0.026 14.9 0.0 0.13 12.7 0.0 2.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 EWM27146.1 - 0.034 14.3 0.0 0.1 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EWM27146.1 - 0.041 13.6 0.3 0.081 12.6 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_19 PF13245.6 EWM27146.1 - 0.063 13.6 0.0 0.25 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 EWM27146.1 - 0.11 11.8 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 EWM27146.1 - 0.12 12.3 0.0 0.37 10.7 0.0 1.8 1 0 0 1 1 1 0 NACHT domain Thioredoxin PF00085.20 EWM27147.1 - 1.4e-23 82.8 0.0 1.7e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EWM27147.1 - 2.7e-08 34.2 0.0 8.2e-08 32.7 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EWM27147.1 - 9e-08 32.2 0.0 1.4e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EWM27147.1 - 0.001 18.9 0.0 0.002 18.0 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 EWM27147.1 - 0.007 16.7 0.0 0.013 15.8 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 EWM27147.1 - 0.052 13.3 0.0 0.2 11.4 0.0 1.8 1 1 1 2 2 2 0 Redoxin TraF PF13728.6 EWM27147.1 - 0.13 12.0 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein DUF1995 PF09353.10 EWM27148.1 - 4.6e-23 82.3 0.0 5.9e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) Vps54 PF07928.12 EWM27149.1 - 2.8e-42 144.3 4.1 7.7e-42 142.9 4.1 1.8 1 0 0 1 1 1 1 Vps54-like protein Vps54_N PF10475.9 EWM27149.1 - 6.9e-08 32.1 0.0 1.4e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 EWM27149.1 - 0.0056 16.8 1.1 0.47 10.6 1.0 2.8 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Apolipoprotein PF01442.18 EWM27149.1 - 0.35 10.7 9.1 11 5.9 2.4 4.1 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain IATP PF04568.12 EWM27149.1 - 2.4 8.6 6.0 0.3 11.6 0.1 2.5 3 0 0 3 3 3 0 Mitochondrial ATPase inhibitor, IATP DUF1491 PF07372.12 EWM27150.1 - 0.091 13.1 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1491) Glyco_trans_1_4 PF13692.6 EWM27152.1 - 1.7e-27 96.4 0.1 4.4e-27 95.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EWM27152.1 - 2.8e-26 92.1 0.0 5.3e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EWM27152.1 - 3.4e-21 76.0 0.6 5.9e-21 75.2 0.6 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EWM27152.1 - 7.2e-13 49.3 0.0 2.7e-12 47.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EWM27152.1 - 3.7e-11 43.3 0.0 7.8e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 EWM27152.1 - 0.033 14.2 0.1 0.049 13.7 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like Phage_Mu_Gam PF07352.12 EWM27153.1 - 0.0098 15.8 0.2 0.041 13.8 0.0 1.9 2 0 0 2 2 2 1 Bacteriophage Mu Gam like protein aGPT-Pplase3 PF18746.1 EWM27153.1 - 0.031 13.7 0.0 0.075 12.4 0.0 1.5 2 0 0 2 2 2 0 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 3 Ribosomal_L18_c PF14204.6 EWM27153.1 - 9.4 7.3 6.5 10 7.2 0.5 2.8 2 2 2 4 4 4 0 Ribosomal L18 C-terminal region PPR_2 PF13041.6 EWM27154.1 - 4e-36 123.0 0.1 4.2e-10 39.7 0.0 6.8 2 1 5 7 7 7 6 PPR repeat family PPR_3 PF13812.6 EWM27154.1 - 3.5e-32 110.3 0.0 5.5e-15 55.2 0.0 5.2 3 1 3 6 6 6 5 Pentatricopeptide repeat domain PPR PF01535.20 EWM27154.1 - 7.7e-31 104.2 4.9 1.7e-05 24.8 0.0 6.3 6 0 0 6 6 6 5 PPR repeat PPR_long PF17177.4 EWM27154.1 - 1.1e-17 64.2 0.0 4.5e-09 36.0 0.0 2.3 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EWM27154.1 - 3e-16 58.8 0.0 6e-05 22.7 0.0 5.5 5 0 0 5 5 5 3 PPR repeat Pkinase PF00069.25 EWM27155.1 - 1.2e-64 218.2 0.0 3.8e-64 216.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM27155.1 - 3.8e-33 114.9 0.0 2e-22 79.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.22 EWM27155.1 - 0.00075 19.1 0.4 0.0021 17.7 0.4 1.7 1 0 0 1 1 1 1 RIO1 family DIRP PF06584.13 EWM27156.1 - 5.2e-18 65.2 0.7 1.2e-17 64.0 0.7 1.6 1 0 0 1 1 1 1 DIRP bZIP_C PF12498.8 EWM27156.1 - 0.0036 18.3 0.2 0.063 14.3 0.1 2.5 2 0 0 2 2 2 1 Basic leucine-zipper C terminal ASF1_hist_chap PF04729.13 EWM27157.1 - 1.1e-67 226.8 0.3 1.5e-67 226.4 0.3 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Nop14 PF04147.12 EWM27157.1 - 1.2 7.2 10.5 1.5 6.9 10.5 1.1 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.16 EWM27157.1 - 2.7 7.1 6.0 4.6 6.4 6.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit ABC2_membrane_5 PF13346.6 EWM27158.1 - 0.014 15.0 0.8 0.02 14.5 0.7 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein TauD PF02668.16 EWM27159.1 - 6.5e-29 101.5 0.0 1.9e-28 100.0 0.0 1.6 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 7TM_GPCR_Srz PF10325.9 EWM27159.1 - 0.17 11.2 0.2 0.24 10.7 0.2 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srz 7TM_GPCR_Srsx PF10320.9 EWM27160.1 - 0.057 12.8 0.7 0.079 12.3 0.7 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx ABC2_membrane PF01061.24 EWM27161.1 - 4.4e-13 49.1 15.2 4.4e-13 49.1 15.2 1.7 2 0 0 2 2 2 1 ABC-2 type transporter Spo7 PF03907.13 EWM27161.1 - 0.069 12.6 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Spo7-like protein ABC2_membrane_3 PF12698.7 EWM27161.1 - 0.32 10.1 11.9 0.5 9.4 11.9 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein DOT1 PF08123.13 EWM27163.1 - 1.4e-14 54.2 0.0 2.5e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 AICARFT_IMPCHas PF01808.18 EWM27164.1 - 2e-82 277.0 0.0 2.7e-82 276.6 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 EWM27164.1 - 3.8e-25 87.9 0.0 8e-25 86.9 0.0 1.6 1 0 0 1 1 1 1 MGS-like domain Lyase_1 PF00206.20 EWM27165.1 - 2.6e-18 66.5 0.0 4.3e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 EWM27165.1 - 5.5e-17 62.1 0.1 1.9e-16 60.3 0.1 2.0 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Ribosomal_S9 PF00380.19 EWM27166.1 - 1.8e-33 115.6 0.1 2.1e-33 115.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 HGTP_anticodon PF03129.20 EWM27167.1 - 2.9e-22 78.6 0.1 1.7e-21 76.1 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EWM27167.1 - 3.5e-11 43.4 0.0 7.9e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ERG4_ERG24 PF01222.17 EWM27168.1 - 5.4e-131 437.3 1.8 1e-119 400.1 1.5 3.0 3 0 0 3 3 3 3 Ergosterol biosynthesis ERG4/ERG24 family Ras PF00071.22 EWM27169.1 - 6.5e-64 214.4 0.0 7.8e-64 214.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EWM27169.1 - 2e-36 124.9 0.1 1.2e-35 122.3 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EWM27169.1 - 7.4e-16 58.1 0.0 8.9e-16 57.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EWM27169.1 - 6.4e-06 25.7 0.0 8.3e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EWM27169.1 - 2e-05 24.3 0.1 5.1e-05 22.9 0.1 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EWM27169.1 - 0.00034 20.1 0.1 0.0012 18.4 0.0 1.6 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EWM27169.1 - 0.00076 19.6 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EWM27169.1 - 0.0019 18.1 0.2 0.27 11.1 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase MCM PF00493.23 EWM27169.1 - 0.025 13.7 0.0 0.073 12.1 0.0 1.7 2 0 0 2 2 2 0 MCM P-loop domain AAA_29 PF13555.6 EWM27169.1 - 0.041 13.6 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 EWM27169.1 - 0.095 12.7 0.0 0.31 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EWM27169.1 - 0.12 12.6 0.1 0.44 10.8 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EWM27169.1 - 0.12 12.7 0.0 0.24 11.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain DAGAT PF03982.13 EWM27171.1 - 3.2e-32 111.6 0.0 4e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Ribosomal_L9_N PF01281.19 EWM27172.1 - 5.3e-15 54.7 1.3 8.1e-15 54.1 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.14 EWM27172.1 - 5e-05 23.7 0.0 9.5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L9, C-terminal domain Aminotran_3 PF00202.21 EWM27173.1 - 1.1e-48 165.9 0.0 1.6e-27 96.2 0.0 3.1 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.6 EWM27173.1 - 5.7e-20 72.0 0.0 1.2e-19 71.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DNA_pol_phi PF04931.13 EWM27174.1 - 1.3e-80 271.6 0.0 6.2e-80 269.3 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase phi DAGAT PF03982.13 EWM27175.1 - 1.7e-41 142.1 0.0 1.9e-41 141.9 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase MTHFR PF02219.17 EWM27176.1 - 3.8e-91 305.4 0.0 5.8e-91 304.8 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Csm1_N PF18504.1 EWM27176.1 - 0.059 13.7 0.3 0.16 12.4 0.3 1.7 1 0 0 1 1 1 0 Csm1 N-terminal domain PRKG1_interact PF15898.5 EWM27176.1 - 0.08 13.8 0.1 0.23 12.4 0.1 1.8 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Ssu72 PF04722.13 EWM27177.1 - 2e-53 180.8 0.0 2.5e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 Ssu72-like protein PBP1_TM PF14812.6 EWM27177.1 - 0.075 13.4 3.8 0.15 12.5 3.8 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ferrochelatase PF00762.19 EWM27178.1 - 5.9e-112 373.8 0.0 7.1e-112 373.6 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 EWM27178.1 - 0.00012 22.4 0.1 0.16 12.3 0.0 2.6 2 0 0 2 2 2 2 CbiX HgmA PF04209.13 EWM27178.1 - 0.13 10.9 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 homogentisate 1,2-dioxygenase Gmx_para_CXXCG PF09535.10 EWM27178.1 - 0.14 11.4 0.0 0.33 10.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (Gmx_para_CXXCG) NIF PF03031.18 EWM27179.1 - 1.8e-40 138.3 0.0 2.5e-40 137.8 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase UDG PF03167.19 EWM27180.1 - 2.2e-09 37.5 0.0 3.5e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily ABC_tran PF00005.27 EWM27181.1 - 1.5e-20 74.1 0.1 4.2e-20 72.7 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EWM27181.1 - 6.5e-05 22.9 0.1 0.054 13.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EWM27181.1 - 0.00018 22.0 0.0 0.00062 20.2 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 EWM27181.1 - 0.00092 19.5 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EWM27181.1 - 0.0012 18.8 0.1 0.003 17.5 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 EWM27181.1 - 0.0013 19.3 0.1 0.0042 17.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EWM27181.1 - 0.0024 18.2 0.0 0.0074 16.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 EWM27181.1 - 0.0025 17.3 0.1 0.073 12.5 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 EWM27181.1 - 0.0029 17.2 0.0 0.0052 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 EWM27181.1 - 0.0035 17.3 0.0 0.0067 16.4 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 EWM27181.1 - 0.0037 17.7 0.0 0.021 15.3 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 EWM27181.1 - 0.0061 16.3 0.2 0.018 14.8 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EWM27181.1 - 0.0061 17.1 0.7 0.02 15.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 EWM27181.1 - 0.014 14.7 0.4 0.026 13.9 0.4 1.3 1 0 0 1 1 1 0 KaiC Rad51 PF08423.11 EWM27181.1 - 0.02 14.2 0.1 0.034 13.4 0.1 1.3 1 0 0 1 1 1 0 Rad51 PduV-EutP PF10662.9 EWM27181.1 - 0.051 13.3 0.0 0.37 10.5 0.1 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 EWM27181.1 - 0.068 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 EWM27181.1 - 0.094 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein ATPase_2 PF01637.18 EWM27181.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 EWM27181.1 - 0.19 12.1 0.0 0.37 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 EWM27181.1 - 0.19 11.4 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EWM27181.1 - 0.21 11.3 0.3 0.4 10.4 0.3 1.3 1 0 0 1 1 1 0 AAA domain Ribosomal_L1 PF00687.21 EWM27182.1 - 1.1e-45 155.9 0.0 1.4e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family ESCRT-II PF05871.12 EWM27184.1 - 1.1e-38 132.6 0.0 1.5e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit TPR_2 PF07719.17 EWM27185.1 - 5.4e-12 44.9 15.8 0.00032 20.6 0.0 8.5 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_12 PF13424.6 EWM27185.1 - 1.8e-10 41.0 4.0 0.0034 17.6 0.5 6.1 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EWM27185.1 - 5.5e-09 36.5 4.3 0.0028 18.3 0.0 4.5 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 EWM27185.1 - 3.3e-08 33.9 8.9 0.00099 19.6 0.0 5.1 5 1 1 6 6 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EWM27185.1 - 4.2e-07 30.1 11.0 0.0017 18.5 1.5 4.5 1 1 3 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EWM27185.1 - 9.6e-07 28.4 1.7 10 6.4 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EWM27185.1 - 1.4e-05 25.5 1.5 0.092 13.6 0.0 5.2 4 2 2 6 6 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EWM27185.1 - 0.00021 21.0 17.2 0.032 14.0 0.1 7.0 9 1 1 10 10 10 2 Tetratricopeptide repeat TPR_6 PF13174.6 EWM27185.1 - 0.00032 21.1 0.4 1.3 9.8 0.0 5.4 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EWM27185.1 - 0.0075 15.9 12.2 0.05 13.3 1.4 4.4 4 0 0 4 4 4 2 TPR repeat TPR_18 PF13512.6 EWM27185.1 - 0.025 14.7 4.8 2.6 8.2 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EWM27185.1 - 0.059 13.4 9.1 1.5 8.8 4.2 3.9 2 1 3 5 5 5 0 Putative TPR-like repeat TPR_9 PF13371.6 EWM27185.1 - 0.088 13.0 2.2 6.9 6.9 0.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EWM27185.1 - 0.12 12.6 9.6 3.1 8.3 0.1 5.9 7 0 0 7 7 6 0 Tetratricopeptide repeat MIT PF04212.18 EWM27185.1 - 0.41 10.7 4.5 8.6 6.5 0.7 4.0 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 EWM27185.1 - 0.9 9.5 5.5 0.95 9.4 0.0 3.7 5 0 0 5 5 3 0 Tetratricopeptide repeat N2227 PF07942.12 EWM27186.1 - 1.4e-75 254.0 0.0 8e-39 133.5 0.0 2.1 2 0 0 2 2 2 2 N2227-like protein Tim17 PF02466.19 EWM27187.1 - 0.068 13.6 2.3 0.12 12.7 2.3 1.4 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Tim17 PF02466.19 EWM27188.1 - 0.00014 22.2 1.5 0.0003 21.1 1.5 1.5 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Romo1 PF10247.9 EWM27188.1 - 1.5 9.2 5.8 5.1 7.5 5.8 2.0 1 1 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 Methyltransf_25 PF13649.6 EWM27190.1 - 7.6e-11 42.6 0.1 3.5e-10 40.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EWM27190.1 - 2.7e-10 40.2 0.0 4.1e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EWM27190.1 - 8.1e-10 38.7 0.0 1.5e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM27190.1 - 5.1e-08 33.5 0.1 5e-07 30.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 EWM27190.1 - 1.4e-05 24.2 0.1 2.2e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Met_10 PF02475.16 EWM27190.1 - 0.0005 19.9 0.0 0.00098 18.9 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.6 EWM27190.1 - 0.00053 19.9 0.0 0.0012 18.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EWM27190.1 - 0.0021 17.6 0.2 0.0036 16.9 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 EWM27190.1 - 0.0039 16.5 0.0 0.0059 15.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 EWM27190.1 - 0.0069 17.1 0.0 0.016 16.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EWM27190.1 - 0.17 11.6 0.1 0.35 10.6 0.1 1.5 1 0 0 1 1 1 0 Lysine methyltransferase Cons_hypoth95 PF03602.15 EWM27190.1 - 0.21 11.2 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 SIR2 PF02146.17 EWM27191.1 - 2.8e-20 73.0 0.0 4.7e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 EWM27191.1 - 0.017 14.9 0.0 0.57 9.9 0.0 2.6 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain EB1 PF03271.17 EWM27192.1 - 7.2e-10 38.9 2.2 7.2e-10 38.9 2.2 2.0 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.31 EWM27192.1 - 7.4e-10 39.0 0.6 1.3e-09 38.2 0.6 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Suppressor_APC PF11414.8 EWM27192.1 - 0.0005 20.1 1.8 0.00059 19.9 0.7 1.7 2 0 0 2 2 2 1 Adenomatous polyposis coli tumour suppressor protein CH_2 PF06294.11 EWM27192.1 - 0.0022 18.1 0.2 0.0047 17.0 0.2 1.6 1 0 0 1 1 1 1 CH-like domain in sperm protein SUIM_assoc PF16619.5 EWM27192.1 - 0.0062 16.6 0.5 0.015 15.3 0.5 1.7 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Herpes_UL6 PF01763.16 EWM27192.1 - 0.016 13.7 0.1 0.02 13.4 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like JIP_LZII PF16471.5 EWM27192.1 - 0.039 14.1 1.2 0.11 12.7 1.2 1.7 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II bZIP_1 PF00170.21 EWM27192.1 - 0.051 13.7 0.3 0.13 12.4 0.3 1.6 1 0 0 1 1 1 0 bZIP transcription factor EB1 PF03271.17 EWM27193.1 - 6.7e-10 39.1 2.2 6.7e-10 39.1 2.2 2.1 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.31 EWM27193.1 - 6.7e-10 39.1 0.6 1.2e-09 38.3 0.6 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Suppressor_APC PF11414.8 EWM27193.1 - 0.00046 20.2 1.8 0.00054 20.0 0.7 1.7 2 0 0 2 2 2 1 Adenomatous polyposis coli tumour suppressor protein CH_2 PF06294.11 EWM27193.1 - 0.002 18.2 0.2 0.0043 17.1 0.2 1.6 1 0 0 1 1 1 1 CH-like domain in sperm protein SUIM_assoc PF16619.5 EWM27193.1 - 0.0061 16.6 0.5 0.014 15.4 0.5 1.6 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Herpes_UL6 PF01763.16 EWM27193.1 - 0.015 13.9 0.1 0.018 13.6 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like JIP_LZII PF16471.5 EWM27193.1 - 0.037 14.2 1.2 0.1 12.8 1.2 1.7 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II bZIP_1 PF00170.21 EWM27193.1 - 0.05 13.7 0.3 0.12 12.5 0.3 1.5 1 0 0 1 1 1 0 bZIP transcription factor Aha1_N PF09229.11 EWM27195.1 - 6e-22 78.3 0.0 1.1e-21 77.4 0.0 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal TPR_1 PF00515.28 EWM27195.1 - 3.3e-13 48.8 5.3 2.8e-07 30.1 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EWM27195.1 - 2.3e-08 33.5 5.2 0.0028 17.6 0.1 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EWM27195.1 - 7.2e-08 32.1 2.7 0.00084 19.4 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EWM27195.1 - 3.1e-07 29.9 1.4 0.69 9.7 0.5 3.4 3 0 0 3 3 3 3 TPR repeat TPR_14 PF13428.6 EWM27195.1 - 8e-06 26.2 0.4 0.015 16.0 0.0 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EWM27195.1 - 0.00046 20.4 1.0 0.39 11.2 0.1 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EWM27195.1 - 0.0007 20.2 12.5 0.0024 18.5 4.5 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TOM20_plant PF06552.12 EWM27195.1 - 0.022 14.5 2.7 0.078 12.7 1.6 2.2 2 1 1 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_19 PF14559.6 EWM27195.1 - 0.4 11.2 4.0 14 6.3 0.7 3.3 2 1 1 4 4 4 0 Tetratricopeptide repeat NUDIX PF00293.28 EWM27196.1 - 1.9e-13 50.6 0.1 2.9e-13 50.0 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain Syntaxin-18_N PF10496.9 EWM27197.1 - 3.3e-07 30.5 0.0 5.4e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 SNARE-complex protein Syntaxin-18 N-terminus DUF3510 PF12022.8 EWM27197.1 - 0.022 15.1 0.0 0.039 14.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) G2BR PF18442.1 EWM27197.1 - 5.5 6.7 7.3 6.5 6.5 0.7 2.5 3 0 0 3 3 3 0 E3 gp78 Ube2g2-binding region (G2BR) NAD_kinase PF01513.21 EWM27198.1 - 6.6e-15 55.1 0.0 1.2e-08 34.5 0.0 2.6 2 1 0 2 2 2 2 ATP-NAD kinase DAGK_cat PF00781.24 EWM27198.1 - 0.0023 17.6 0.0 0.0042 16.7 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF647 PF04884.14 EWM27199.1 - 4.7e-80 268.7 1.4 6.4e-80 268.2 1.4 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DUF1336 PF07059.12 EWM27200.1 - 2e-58 198.2 0.0 2.9e-58 197.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) START PF01852.19 EWM27200.1 - 3.8e-15 55.9 0.0 8.3e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 START domain PH PF00169.29 EWM27200.1 - 2.2e-10 41.0 0.1 1.9e-07 31.6 0.0 2.4 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 EWM27200.1 - 0.00063 20.1 0.2 0.0048 17.3 0.2 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 EWM27200.1 - 0.034 14.4 0.2 0.23 11.8 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain G10 PF01125.17 EWM27201.1 - 2.4e-53 179.8 1.3 4e-53 179.1 1.3 1.4 1 0 0 1 1 1 1 G10 protein Ribosomal_60s PF00428.19 EWM27201.1 - 0.03 14.9 12.5 0.054 14.1 12.5 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Paf1 PF03985.13 EWM27201.1 - 4.5 6.2 8.1 6.5 5.6 8.1 1.2 1 0 0 1 1 1 0 Paf1 XPG_I PF00867.18 EWM27203.1 - 5.8e-16 58.6 0.0 1.1e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EWM27203.1 - 9.3e-14 51.7 0.0 1.8e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain Aminotran_1_2 PF00155.21 EWM27204.1 - 2.4e-83 280.3 0.0 2.7e-83 280.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Thioredoxin_8 PF13905.6 EWM27205.1 - 1.5e-46 156.6 0.1 1.6e-29 102.1 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 EWM27205.1 - 3.7e-11 43.0 0.3 7.9e-07 29.0 0.0 3.4 2 1 1 3 3 3 2 AhpC/TSA family Thioredoxin PF00085.20 EWM27205.1 - 9.4e-10 38.4 0.7 7.2e-07 29.1 0.3 3.0 3 1 1 4 4 4 2 Thioredoxin Thioredoxin_2 PF13098.6 EWM27205.1 - 4.2e-08 33.6 1.3 6.1e-06 26.7 0.1 2.8 3 0 0 3 3 3 1 Thioredoxin-like domain Redoxin PF08534.10 EWM27205.1 - 0.0003 20.5 0.0 0.0016 18.2 0.0 2.1 2 0 0 2 2 2 1 Redoxin Thioredoxin_7 PF13899.6 EWM27205.1 - 0.00031 20.9 0.0 0.0014 18.8 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 EWM27205.1 - 0.088 12.6 0.0 2 8.2 0.0 2.8 3 0 0 3 3 3 0 Thioredoxin ATPase PF06745.13 EWM27205.1 - 0.17 11.2 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 KaiC SCO1-SenC PF02630.14 EWM27205.1 - 0.18 11.7 0.3 1 9.3 0.0 2.3 3 0 0 3 3 3 0 SCO1/SenC CK_II_beta PF01214.18 EWM27206.1 - 1.6e-48 165.0 0.0 7.4e-30 104.1 0.0 2.2 2 0 0 2 2 2 2 Casein kinase II regulatory subunit Mito_carr PF00153.27 EWM27207.1 - 2.4e-34 117.1 8.1 7.7e-19 67.4 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Methyltransf_25 PF13649.6 EWM27208.1 - 3e-05 24.7 0.0 9e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EWM27208.1 - 5.2e-05 22.8 0.0 8.4e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 EWM27208.1 - 5.9e-05 23.7 0.1 0.001 19.8 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain TPR_2 PF07719.17 EWM27208.1 - 0.00079 19.4 0.1 0.004 17.2 0.1 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat Imm_superinfect PF14373.6 EWM27208.1 - 0.0059 16.5 0.1 0.015 15.2 0.1 1.7 1 0 0 1 1 1 1 Superinfection immunity protein TPR_1 PF00515.28 EWM27208.1 - 0.0068 16.2 0.0 0.017 14.9 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat Methyltransf_23 PF13489.6 EWM27208.1 - 0.01 15.7 0.0 0.033 14.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 EWM27208.1 - 0.033 13.8 0.0 0.073 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain TPR_14 PF13428.6 EWM27208.1 - 0.86 10.6 5.6 0.53 11.3 1.1 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 EWM27208.1 - 5.9 7.6 10.7 0.51 11.0 0.4 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat RIBIOP_C PF04950.12 EWM27209.1 - 1.2e-104 349.9 0.0 2e-104 349.2 0.0 1.3 1 1 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Nop53 PF07767.11 EWM27209.1 - 5 6.4 14.1 2.7 7.3 10.8 2.0 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Dynamin_N PF00350.23 EWM27210.1 - 1.7e-07 31.4 0.0 5e-05 23.4 0.0 3.0 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 EWM27210.1 - 0.00012 22.1 0.0 0.00033 20.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF5600 PF18150.1 EWM27210.1 - 0.0043 17.6 0.1 1.3 9.6 0.0 2.6 3 0 0 3 3 3 2 Domain of unknown function (DUF5600) ERO1 PF04137.15 EWM27211.1 - 5.6e-117 390.9 0.0 6.9e-117 390.6 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Glyco_trans_1_4 PF13692.6 EWM27212.1 - 3.2e-11 43.8 0.0 8.3e-11 42.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EWM27212.1 - 3.3e-10 39.8 0.0 6.2e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EWM27212.1 - 0.024 15.0 2.5 0.029 14.7 0.0 2.4 3 0 0 3 3 3 0 Glycosyl transferases group 1 WD40 PF00400.32 EWM27213.1 - 2.7e-08 34.3 14.3 0.0048 17.7 0.2 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM27213.1 - 3.6e-05 24.0 0.0 0.82 10.0 0.0 3.4 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1513 PF07433.11 EWM27213.1 - 0.042 12.9 0.7 8.4 5.4 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) Nup160 PF11715.8 EWM27213.1 - 0.17 10.5 0.2 8.4 4.9 0.0 2.7 3 0 0 3 3 3 0 Nucleoporin Nup120/160 RNase_PH PF01138.21 EWM27214.1 - 5.5e-35 120.8 0.2 2.2e-21 76.7 0.0 2.4 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EWM27214.1 - 1.8e-17 63.1 0.3 1.3e-12 47.6 0.0 3.0 2 1 0 2 2 2 2 3' exoribonuclease family, domain 2 S1 PF00575.23 EWM27214.1 - 1.5e-13 50.9 0.9 4.9e-13 49.2 0.3 2.2 2 0 0 2 2 2 1 S1 RNA binding domain IMS PF00817.20 EWM27215.1 - 1.2e-44 152.0 0.1 1.9e-44 151.3 0.1 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EWM27215.1 - 2e-08 34.9 0.3 5.4e-08 33.6 0.3 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain UBM PF14377.6 EWM27215.1 - 5.8e-05 22.4 0.1 0.00019 20.8 0.1 1.9 1 0 0 1 1 1 1 Ubiquitin binding region IMS_HHH PF11798.8 EWM27215.1 - 0.065 13.6 0.2 0.17 12.3 0.2 1.6 1 0 0 1 1 1 0 IMS family HHH motif RrnaAD PF00398.20 EWM27216.1 - 1.1e-37 129.6 0.0 4.1e-37 127.7 0.0 1.7 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.6 EWM27216.1 - 0.00072 19.4 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EWM27216.1 - 0.0051 16.4 0.0 0.0084 15.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EWM27216.1 - 0.0061 17.2 0.0 0.012 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM27216.1 - 0.038 14.6 0.0 0.077 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 EWM27216.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase zf-C3HC4_3 PF13920.6 EWM27218.1 - 8.6e-08 31.9 1.5 8.6e-08 31.9 1.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EWM27218.1 - 2.9e-06 27.0 2.6 2.9e-06 27.0 2.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EWM27218.1 - 3.4e-06 27.3 4.3 3.4e-06 27.3 4.3 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EWM27218.1 - 0.00015 21.5 3.7 0.00015 21.5 3.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EWM27218.1 - 0.00016 21.5 3.2 0.00016 21.5 3.2 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EWM27218.1 - 0.00016 21.9 2.0 0.00016 21.9 2.0 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EWM27218.1 - 0.0018 18.2 2.8 0.0018 18.2 2.8 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EWM27218.1 - 0.0077 16.2 5.3 0.011 15.8 1.6 2.6 2 0 0 2 2 2 1 RING-type zinc-finger ApoM PF11032.8 EWM27218.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 ApoM domain ABC2_membrane PF01061.24 EWM27219.1 - 5.8e-68 228.4 55.5 9.1e-37 126.5 20.9 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EWM27219.1 - 1e-33 116.7 0.0 8.6e-18 65.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 EWM27219.1 - 1.9e-11 43.7 43.2 1.7e-07 30.7 12.5 2.9 2 1 0 2 2 2 2 ABC-2 family transporter protein PDR_assoc PF08370.11 EWM27219.1 - 8.3e-10 38.3 1.6 3.1e-09 36.4 1.6 2.0 1 0 0 1 1 1 1 Plant PDR ABC transporter associated AAA_21 PF13304.6 EWM27219.1 - 3.3e-07 30.4 0.0 0.04 13.7 0.0 4.1 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EWM27219.1 - 0.00028 20.6 1.2 0.042 13.6 0.5 2.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EWM27219.1 - 0.00037 20.4 0.4 0.0098 15.8 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EWM27219.1 - 0.00038 20.9 4.7 0.089 13.2 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_28 PF13521.6 EWM27219.1 - 0.00071 19.8 3.2 0.65 10.2 0.1 3.2 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.6 EWM27219.1 - 0.0022 17.6 0.7 2.5 7.6 0.3 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 EWM27219.1 - 0.0051 17.2 1.5 0.55 10.6 0.1 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 EWM27219.1 - 0.0058 16.4 1.7 2.2 8.0 0.1 2.6 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 EWM27219.1 - 0.02 14.9 0.5 6.5 6.9 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.6 EWM27219.1 - 0.029 14.1 0.1 4 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 EWM27219.1 - 0.038 13.5 0.1 4.8 6.7 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_30 PF13604.6 EWM27219.1 - 0.042 13.6 0.5 6.3 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EWM27219.1 - 0.05 13.9 1.9 1.5 9.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EWM27219.1 - 0.065 13.5 2.4 2.7 8.3 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.6 EWM27219.1 - 0.065 13.7 0.2 5.3 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EWM27219.1 - 0.078 12.9 0.1 0.76 9.6 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_15 PF13175.6 EWM27219.1 - 0.098 12.3 0.0 18 4.9 0.0 3.0 4 0 0 4 4 3 0 AAA ATPase domain Dynamin_N PF00350.23 EWM27219.1 - 0.14 12.2 0.6 12 5.9 0.0 2.5 2 0 0 2 2 2 0 Dynamin family Zeta_toxin PF06414.12 EWM27219.1 - 0.15 11.3 0.9 8 5.7 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin RseA_C PF03873.13 EWM27220.1 - 1.7 9.0 3.9 1.4 9.2 0.2 2.7 3 0 0 3 3 3 0 Anti sigma-E protein RseA, C-terminal domain TMEM206 PF15122.6 EWM27222.1 - 0.017 14.3 0.2 0.018 14.2 0.2 1.1 1 0 0 1 1 1 0 TMEM206 protein family FCH PF00611.23 EWM27222.1 - 0.073 13.4 0.0 0.076 13.3 0.0 1.1 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain HEAT_2 PF13646.6 EWM27223.1 - 0.027 14.8 0.3 0.96 9.9 0.1 2.4 2 0 0 2 2 2 0 HEAT repeats Arm PF00514.23 EWM27223.1 - 0.053 13.6 1.4 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EWM27223.1 - 0.11 12.9 1.1 11 6.6 0.0 2.9 2 0 0 2 2 2 0 HEAT repeat Kinesin PF00225.23 EWM27224.1 - 5.3e-100 334.6 0.0 7.8e-100 334.0 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EWM27224.1 - 1.2e-22 80.4 0.0 2.9e-21 76.0 0.0 2.4 1 1 0 1 1 1 1 Microtubule binding HOOK PF05622.12 EWM27224.1 - 6.7 4.7 9.7 0.42 8.7 0.7 2.6 3 0 0 3 3 3 0 HOOK protein GRIP PF01465.20 EWM27225.1 - 0.049 13.6 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 GRIP domain Dus PF01207.17 EWM27226.1 - 2e-56 191.4 0.0 2.8e-56 190.9 0.0 1.3 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) MR_MLE_C PF13378.6 EWM27226.1 - 0.012 15.2 0.1 0.046 13.3 0.1 1.9 1 1 0 1 1 1 0 Enolase C-terminal domain-like ThiG PF05690.14 EWM27226.1 - 0.085 12.2 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG BKACE PF05853.12 EWM27226.1 - 0.11 11.8 0.1 0.2 10.9 0.1 1.4 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme PEP_hydrolase PF09370.10 EWM27226.1 - 0.24 10.6 0.0 14 4.8 0.0 2.6 2 1 1 3 3 3 0 Phosphoenolpyruvate hydrolase-like Tub PF01167.18 EWM27227.1 - 3.4e-31 108.9 0.0 5e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Tub family DUF3527 PF12043.8 EWM27227.1 - 0.00026 20.7 0.0 0.00053 19.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3527) SelR PF01641.18 EWM27229.1 - 1.6e-38 131.5 0.1 2.3e-38 131.0 0.1 1.2 1 0 0 1 1 1 1 SelR domain SpoVS PF04232.12 EWM27229.1 - 0.19 11.5 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 Stage V sporulation protein S (SpoVS) SET PF00856.28 EWM27230.1 - 2.2e-18 67.2 2.0 2.1e-17 64.0 0.3 2.9 3 1 0 3 3 3 1 SET domain AWS PF17907.1 EWM27230.1 - 4.2e-08 33.1 6.8 4.2e-08 33.1 6.8 2.9 3 0 0 3 3 3 1 AWS domain PHD_2 PF13831.6 EWM27230.1 - 2.6e-06 26.9 4.0 7.2e-06 25.5 4.0 1.8 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 EWM27230.1 - 1.9e-05 24.5 12.6 1.9e-05 24.5 12.6 2.2 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 EWM27231.1 - 8.4e-11 42.0 3.5 1.4e-10 41.3 3.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EWM27231.1 - 7.6e-08 32.1 3.1 1.4e-07 31.2 3.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EWM27231.1 - 3.3e-06 26.7 0.6 3.3e-06 26.7 0.6 1.8 2 0 0 2 2 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EWM27231.1 - 5.4e-06 26.3 0.4 1.1e-05 25.3 0.0 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EWM27231.1 - 7e-06 26.2 4.3 2.1e-05 24.7 4.3 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EWM27231.1 - 8.7e-06 25.5 2.2 1.5e-05 24.8 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EWM27231.1 - 0.00011 22.0 4.9 0.00024 20.9 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EWM27231.1 - 0.00022 21.1 4.4 0.00037 20.4 4.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EWM27231.1 - 0.0021 17.9 5.3 0.0059 16.4 5.3 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 EWM27231.1 - 0.0093 15.6 4.6 0.016 14.8 4.6 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 EWM27231.1 - 0.019 14.8 1.1 0.034 14.0 1.1 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 EWM27231.1 - 0.077 13.1 1.9 0.15 12.1 1.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger XRN_M PF17846.1 EWM27232.1 - 4.1e-135 451.2 0.0 4.9e-95 319.1 0.0 2.3 2 0 0 2 2 2 2 Xrn1 helical domain XRN_N PF03159.18 EWM27232.1 - 8.9e-95 316.7 0.0 2e-94 315.6 0.0 1.6 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus Spt20 PF12090.8 EWM27232.1 - 2.2 7.8 9.1 4.7 6.8 9.1 1.4 1 0 0 1 1 1 0 Spt20 family HALZ PF02183.18 EWM27233.1 - 0.008 16.4 0.3 0.015 15.5 0.3 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper ACD PF16671.5 EWM27233.1 - 0.066 11.5 1.3 3.2 6.0 0.3 2.1 2 0 0 2 2 2 0 Actin cross-linking domain bZIP_1 PF00170.21 EWM27233.1 - 0.18 11.9 0.7 0.35 11.0 0.7 1.4 1 0 0 1 1 1 0 bZIP transcription factor ZapB PF06005.12 EWM27233.1 - 0.26 11.8 3.4 2.4 8.7 2.0 2.2 2 0 0 2 2 2 0 Cell division protein ZapB YabA PF06156.13 EWM27233.1 - 0.32 11.6 0.7 0.51 11.0 0.7 1.3 1 0 0 1 1 1 0 Initiation control protein YabA Trimer_CC PF08954.11 EWM27233.1 - 0.4 10.3 3.6 2.1 8.0 3.6 2.3 1 0 0 1 1 1 0 Trimerisation motif bZIP_2 PF07716.15 EWM27234.1 - 1e-10 41.5 30.2 5.8e-07 29.5 12.9 2.6 2 0 0 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 EWM27234.1 - 6.1e-06 26.2 22.5 0.0022 18.0 6.7 2.5 2 0 0 2 2 2 2 bZIP transcription factor SR-25 PF10500.9 EWM27234.1 - 0.008 15.8 8.0 0.008 15.8 8.0 3.3 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein bZIP_Maf PF03131.17 EWM27234.1 - 0.5 10.9 21.3 0.43 11.1 3.9 2.7 2 0 0 2 2 2 0 bZIP Maf transcription factor Exo_endo_phos PF03372.23 EWM27235.1 - 0.1 12.1 1.1 0.15 11.6 1.1 1.3 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Cellulose_synt PF03552.14 EWM27236.1 - 0.015 13.8 1.6 0.25 9.8 0.1 2.1 1 1 1 2 2 2 0 Cellulose synthase CcmF_C PF16327.5 EWM27236.1 - 2.2 7.5 7.3 16 4.7 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c-type biogenesis protein CcmF C-terminal DUF2070 PF09843.9 EWM27236.1 - 2.4 6.3 13.4 0.9 7.8 10.7 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) IGPD PF00475.18 EWM27237.1 - 7.8e-58 194.9 3.2 1.5e-57 193.9 3.2 1.5 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase HAD_2 PF13419.6 EWM27237.1 - 2e-18 67.1 0.0 9.4e-18 64.9 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EWM27237.1 - 5.6e-10 39.8 0.1 1.5e-08 35.2 0.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EWM27237.1 - 8e-09 35.4 0.9 2.8e-08 33.7 0.0 2.4 3 0 0 3 3 3 1 HAD-hyrolase-like HAD PF12710.7 EWM27237.1 - 0.027 14.9 0.3 0.063 13.7 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase ATP-synt_DE_N PF02823.16 EWM27238.1 - 1.5e-14 53.7 0.2 2.6e-14 52.9 0.2 1.5 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Pyridoxal_deC PF00282.19 EWM27238.1 - 0.077 11.7 0.0 0.098 11.4 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain zf-TAZ PF02135.16 EWM27239.1 - 1.1e-09 38.6 12.4 1.1e-09 38.6 12.4 2.2 2 0 0 2 2 2 1 TAZ zinc finger Sdh5 PF03937.16 EWM27240.1 - 2.2e-19 69.2 0.0 3.6e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase CHORD PF04968.12 EWM27241.1 - 1.1e-46 157.4 21.6 5.2e-25 87.9 10.4 2.4 2 0 0 2 2 2 2 CHORD BTK PF00779.19 EWM27241.1 - 0.007 16.2 7.6 0.37 10.7 0.4 3.7 4 0 0 4 4 4 2 BTK motif TFR_dimer PF04253.15 EWM27242.1 - 1.6e-28 99.2 0.0 2.4e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EWM27242.1 - 1.9e-18 66.9 0.0 3.4e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EWM27242.1 - 3.4e-14 52.6 0.0 1.1e-13 50.9 0.0 1.9 2 0 0 2 2 2 1 PA domain SBP_bac_5 PF00496.22 EWM27242.1 - 0.00093 18.3 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle Fer2_4 PF13510.6 EWM27242.1 - 0.17 12.0 0.0 0.41 10.7 0.0 1.6 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain SAC3_GANP PF03399.16 EWM27243.1 - 2.9e-26 92.6 0.3 7.3e-25 87.9 0.3 2.1 1 1 0 1 1 1 1 SAC3/GANP family SdiA-regulated PF06977.11 EWM27244.1 - 0.057 12.6 0.0 4.9 6.3 0.0 2.9 3 0 0 3 3 3 0 SdiA-regulated PQQ_2 PF13360.6 EWM27244.1 - 0.1 12.1 0.0 0.97 9.0 0.0 2.3 2 1 0 2 2 2 0 PQQ-like domain GSH_synth_ATP PF03917.17 EWM27247.1 - 1.9e-110 369.2 0.0 5.1e-110 367.8 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 EWM27247.1 - 1.4e-32 112.1 0.0 2.3e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic glutathione synthase FA_desaturase PF00487.24 EWM27249.1 - 6.8e-20 72.0 25.2 6.8e-20 72.0 25.2 2.4 2 1 1 3 3 3 1 Fatty acid desaturase Cyt-b5 PF00173.28 EWM27249.1 - 3.9e-10 39.7 0.0 7.6e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pkinase PF00069.25 EWM27250.1 - 1.1e-28 100.4 0.0 1.7e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM27250.1 - 5.3e-20 71.8 0.0 2.9e-19 69.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EWM27250.1 - 6.8e-05 22.9 0.0 0.0065 16.4 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EWM27250.1 - 0.03 13.1 0.0 0.053 12.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 EWM27250.1 - 0.069 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like PGP_phosphatase PF09419.10 EWM27251.1 - 5.3e-45 153.0 0.0 7.2e-45 152.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 EWM27251.1 - 0.0046 17.0 0.0 0.0093 16.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like DUF1772 PF08592.11 EWM27252.1 - 3.4e-19 69.5 0.8 5.9e-19 68.7 0.8 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) DnaJ PF00226.31 EWM27254.1 - 8.6e-15 54.6 0.0 1.7e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Nop14 PF04147.12 EWM27255.1 - 8.2e-06 24.3 35.6 8.8e-06 24.2 35.6 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 EWM27255.1 - 7.2e-05 22.4 38.7 8.9e-05 22.1 38.7 1.2 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 EWM27255.1 - 0.00031 20.2 37.0 0.00043 19.8 37.0 1.2 1 0 0 1 1 1 1 BUD22 Mpp10 PF04006.12 EWM27255.1 - 0.0072 14.8 41.7 0.0098 14.4 41.7 1.2 1 0 0 1 1 1 1 Mpp10 protein FRQ PF09421.10 EWM27255.1 - 0.082 10.9 15.1 0.098 10.7 15.1 1.1 1 0 0 1 1 1 0 Frequency clock protein V_ATPase_I PF01496.19 EWM27255.1 - 0.26 9.1 13.7 0.31 8.9 13.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lin-8 PF03353.15 EWM27255.1 - 0.28 10.7 19.6 0.3 10.6 19.6 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Presenilin PF01080.17 EWM27255.1 - 0.34 9.6 22.1 0.37 9.5 22.1 1.2 1 0 0 1 1 1 0 Presenilin Raftlin PF15250.6 EWM27255.1 - 0.38 9.5 14.1 0.39 9.4 14.1 1.3 1 0 0 1 1 1 0 Raftlin Peptidase_S64 PF08192.11 EWM27255.1 - 0.48 8.9 9.4 0.52 8.7 9.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF2151 PF10221.9 EWM27255.1 - 1.4 7.4 13.8 1.5 7.3 13.8 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator SID-1_RNA_chan PF13965.6 EWM27255.1 - 2.7 6.3 3.8 3.4 6.0 3.8 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Hid1 PF12722.7 EWM27255.1 - 6.5 4.7 19.1 6.5 4.8 19.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.22 EWM27255.1 - 7.8 5.6 14.8 10 5.2 14.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SLC12 PF03522.15 EWM27255.1 - 8.9 5.2 14.6 11 4.9 14.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF5427 PF10310.9 EWM27255.1 - 9.4 5.1 26.7 14 4.5 26.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) PAP2 PF01569.21 EWM27256.1 - 5.2e-20 71.6 5.8 8.3e-20 70.9 5.8 1.3 1 0 0 1 1 1 1 PAP2 superfamily MerC PF03203.14 EWM27256.1 - 0.024 15.1 3.5 0.077 13.5 0.1 2.5 2 0 0 2 2 2 0 MerC mercury resistance protein YtpI PF14007.6 EWM27256.1 - 0.086 13.0 0.2 19 5.5 0.0 2.6 2 0 0 2 2 2 0 YtpI-like protein CbtB PF09489.10 EWM27256.1 - 0.68 10.1 2.6 1.1 9.4 0.7 2.3 1 1 1 2 2 2 0 Probable cobalt transporter subunit (CbtB) Epimerase PF01370.21 EWM27257.1 - 3.6e-26 92.1 0.0 7.4e-26 91.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EWM27257.1 - 2.9e-18 66.4 0.0 1.1e-17 64.4 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EWM27257.1 - 4.5e-05 22.7 0.0 0.011 14.8 0.0 2.3 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein UDPG_MGDP_dh_N PF03721.14 EWM27257.1 - 0.0017 17.9 0.0 0.0039 16.8 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3Beta_HSD PF01073.19 EWM27257.1 - 0.051 12.6 0.0 0.094 11.7 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Pyr_redox_2 PF07992.14 EWM27257.1 - 0.079 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase VWA_2 PF13519.6 EWM27258.1 - 1.4e-08 35.4 0.0 2.8e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain WW PF00397.26 EWM27258.1 - 0.00016 21.7 0.0 0.00042 20.4 0.0 1.7 1 0 0 1 1 1 1 WW domain Brix PF04427.18 EWM27259.1 - 2.6e-38 132.1 0.0 3.7e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 Brix domain MCU PF04678.13 EWM27259.1 - 1.9 8.5 3.8 3.4 7.7 3.8 1.4 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF1682 PF07946.14 EWM27259.1 - 6.6 5.8 10.3 10 5.2 10.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) UQ_con PF00179.26 EWM27260.1 - 2.2e-13 50.1 0.0 3.3e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DEAD PF00270.29 EWM27261.1 - 4.1e-49 166.7 0.0 1.7e-48 164.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EWM27261.1 - 9.2e-34 116.1 0.0 8e-33 113.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EWM27261.1 - 3.5e-06 27.1 0.0 3.4e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit YopX PF09643.10 EWM27262.1 - 0.089 12.9 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 YopX protein Not1 PF04054.15 EWM27263.1 - 1.3e-143 478.4 0.0 1.3e-143 478.4 0.0 3.4 3 1 1 4 4 4 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 EWM27263.1 - 3.8e-84 281.6 2.1 2.5e-80 269.1 0.3 2.6 2 0 0 2 2 2 2 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 EWM27263.1 - 8.4e-66 220.8 0.0 8.4e-66 220.8 0.0 5.2 5 0 0 5 5 5 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 EWM27263.1 - 5.4e-59 198.3 0.4 5.4e-59 198.3 0.4 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 EWM27263.1 - 4.3e-13 49.6 0.0 4.3e-13 49.6 0.0 5.2 5 0 0 5 5 5 1 CCR4-NOT transcription complex subunit 1 HEAT repeat SUIM_assoc PF16619.5 EWM27263.1 - 0.0017 18.4 0.1 0.0017 18.4 0.1 9.9 6 2 2 8 8 8 1 Unstructured region C-term to UIM in Ataxin3 HEAT PF02985.22 EWM27265.1 - 8.9e-16 56.6 13.5 0.014 15.6 0.0 9.9 12 0 0 12 12 12 4 HEAT repeat HEAT_EZ PF13513.6 EWM27265.1 - 4.4e-14 52.6 16.0 8.5e-11 42.1 0.0 7.7 8 1 0 8 8 8 1 HEAT-like repeat IBN_N PF03810.19 EWM27265.1 - 1.3e-10 41.1 0.4 2.8e-09 36.7 0.5 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 EWM27265.1 - 3.4e-10 40.2 8.0 0.0014 19.0 0.0 6.8 4 2 4 8 8 8 5 HEAT repeats Cnd1 PF12717.7 EWM27265.1 - 4.3e-05 23.6 0.0 0.0051 16.9 0.0 3.5 2 2 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EWM27265.1 - 6.3e-05 23.5 0.4 57 4.4 0.0 5.8 5 1 2 7 7 7 0 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 EWM27265.1 - 0.00016 21.3 0.1 0.51 9.9 0.1 3.9 5 1 0 5 5 5 2 CLASP N terminal Arm PF00514.23 EWM27265.1 - 0.0011 18.9 8.3 0.56 10.3 0.0 6.5 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 EWM27265.1 - 0.0025 16.4 0.9 0.081 11.5 0.0 3.1 2 1 2 4 4 4 1 Adaptin N terminal region IFRD PF05004.13 EWM27265.1 - 0.027 13.6 1.2 20 4.1 0.0 4.7 4 1 1 5 5 5 0 Interferon-related developmental regulator (IFRD) DUF577 PF04510.12 EWM27265.1 - 0.033 14.1 0.0 0.13 12.1 0.0 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF577) Cnd3 PF12719.7 EWM27265.1 - 0.07 12.3 1.8 1.5 7.9 0.4 3.4 3 1 1 4 4 4 0 Nuclear condensing complex subunits, C-term domain Synaptobrevin PF00957.21 EWM27266.1 - 5.1e-21 74.3 4.6 5.1e-21 74.3 4.6 1.6 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.6 EWM27266.1 - 1.6e-05 24.8 0.0 3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF805 PF05656.14 EWM27266.1 - 0.013 15.9 0.1 0.022 15.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF805) Memo PF01875.17 EWM27269.1 - 4.2e-78 262.2 0.0 4.8e-78 262.0 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein STI1 PF17830.1 EWM27269.1 - 0.064 13.2 0.0 5 7.1 0.0 3.3 4 0 0 4 4 4 0 STI1 domain TPR_16 PF13432.6 EWM27271.1 - 1.5e-05 25.5 0.0 3.6e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 EWM27271.1 - 0.00066 19.9 0.4 0.011 16.0 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EWM27271.1 - 0.00096 19.1 0.0 0.23 11.7 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EWM27271.1 - 0.0027 17.4 0.0 0.0053 16.4 0.0 1.5 1 0 0 1 1 1 1 TPR repeat TPR_19 PF14559.6 EWM27271.1 - 0.028 14.9 0.0 0.082 13.4 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 EWM27271.1 - 0.076 12.9 0.0 1.5 8.8 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EWM27271.1 - 0.14 12.4 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 FGE-sulfatase PF03781.16 EWM27272.1 - 2.2e-71 240.5 8.2 2.8e-71 240.2 8.2 1.1 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Actin PF00022.19 EWM27273.1 - 2.3e-98 329.5 0.0 2.6e-98 329.3 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EWM27273.1 - 0.00011 21.2 0.0 0.003 16.4 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein DUF1644 PF07800.12 EWM27273.1 - 0.071 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) LMBR1 PF04791.16 EWM27274.1 - 6.4e-53 180.4 37.2 4e-32 111.8 5.4 2.0 1 1 1 2 2 2 2 LMBR1-like membrane protein SAP PF02037.27 EWM27275.1 - 7.5e-06 25.6 0.1 1.7e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 SAP domain MRP-S33 PF08293.11 EWM27276.1 - 6.7e-08 32.7 0.0 1.4e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 DcpS_C PF11969.8 EWM27277.1 - 2e-23 83.0 0.0 4.2e-23 82.0 0.0 1.6 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS_C PF11969.8 EWM27278.1 - 1.9e-11 44.5 0.0 4.4e-11 43.2 0.0 1.6 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Glyco_transf_90 PF05686.12 EWM27280.1 - 2.7e-28 99.0 0.0 3.7e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 TPR_MLP1_2 PF07926.12 EWM27281.1 - 3.8e-10 39.9 25.4 3.8e-10 39.9 25.4 14.9 5 5 10 15 15 15 4 TPR/MLP1/MLP2-like protein PhaC_N PF07167.13 EWM27281.1 - 0.17 11.5 4.0 2.1 8.0 0.9 3.5 2 0 0 2 2 2 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus TPR_10 PF13374.6 EWM27281.1 - 3.2 7.7 9.0 0.36 10.8 0.5 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA PF00004.29 EWM27282.1 - 5.6e-17 62.4 0.0 9.8e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EWM27282.1 - 6.7e-15 55.2 0.0 3.3e-13 49.8 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 EWM27282.1 - 8.5e-08 32.3 0.0 1.5e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 EWM27282.1 - 4.6e-06 27.1 0.0 6.4e-05 23.4 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_11 PF13086.6 EWM27282.1 - 6.8e-05 22.8 0.1 0.0003 20.7 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.6 EWM27282.1 - 8.7e-05 22.3 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EWM27282.1 - 0.0001 22.1 0.0 0.00032 20.5 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EWM27282.1 - 0.00012 22.3 0.0 0.0099 16.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EWM27282.1 - 0.00026 21.1 0.0 0.00064 19.8 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 EWM27282.1 - 0.0006 19.9 0.0 0.0013 18.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EWM27282.1 - 0.00075 18.9 0.0 0.036 13.5 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 EWM27282.1 - 0.0018 17.6 0.0 0.024 13.9 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 EWM27282.1 - 0.0019 18.5 0.0 0.0082 16.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EWM27282.1 - 0.0023 17.9 0.0 0.01 15.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EWM27282.1 - 0.0048 16.7 0.0 0.0093 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EWM27282.1 - 0.0075 15.8 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_3 PF07726.11 EWM27282.1 - 0.013 15.3 0.0 0.037 13.9 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 EWM27282.1 - 0.015 14.5 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATPase_2 PF01637.18 EWM27282.1 - 0.037 14.0 0.0 0.05 13.5 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea PhoH PF02562.16 EWM27282.1 - 0.043 13.3 0.2 2.5 7.5 0.0 2.5 2 1 0 2 2 2 0 PhoH-like protein DEAD PF00270.29 EWM27282.1 - 0.047 13.5 0.1 0.42 10.4 0.0 2.0 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_28 PF13521.6 EWM27282.1 - 0.058 13.6 0.1 0.13 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain MCM PF00493.23 EWM27282.1 - 0.11 11.6 0.0 0.27 10.3 0.0 1.6 1 1 0 1 1 1 0 MCM P-loop domain AAA_23 PF13476.6 EWM27282.1 - 0.12 12.8 0.0 0.14 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EWM27282.1 - 0.16 11.6 0.0 13 5.4 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain RsgA_GTPase PF03193.16 EWM27282.1 - 0.17 11.8 0.0 0.76 9.7 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase C2 PF00168.30 EWM27283.1 - 2.1e-08 34.4 0.0 6.9e-08 32.7 0.0 1.9 1 0 0 1 1 1 1 C2 domain SMP_LBD PF17047.5 EWM27283.1 - 0.00065 19.2 0.0 0.00096 18.7 0.0 1.3 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain HTH_Tnp_Tc5 PF03221.16 EWM27285.1 - 0.051 13.6 0.1 5.6 7.1 0.1 2.8 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain Flavin_Reduct PF01613.18 EWM27285.1 - 0.12 12.5 0.0 0.36 10.9 0.0 1.7 2 0 0 2 2 2 0 Flavin reductase like domain ABC_tran PF00005.27 EWM27286.1 - 2e-49 167.6 0.0 1.6e-24 87.0 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EWM27286.1 - 3.6e-19 69.7 0.9 0.00019 21.4 0.0 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 EWM27286.1 - 3.1e-12 46.4 4.3 8.9e-12 44.9 3.1 2.1 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EWM27286.1 - 4.8e-07 29.4 3.1 1.4 8.3 0.0 4.2 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EWM27286.1 - 6e-06 25.9 0.5 0.051 13.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EWM27286.1 - 4.7e-05 23.4 0.0 0.12 12.5 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase MeaB PF03308.16 EWM27286.1 - 0.0015 17.6 0.3 0.73 8.8 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 EWM27286.1 - 0.0015 18.4 0.7 0.82 9.5 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 EWM27286.1 - 0.0018 18.8 6.9 0.17 12.4 0.0 3.1 4 0 0 4 4 3 2 AAA domain SbcCD_C PF13558.6 EWM27286.1 - 0.002 18.3 0.7 7 7.0 0.1 3.8 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 EWM27286.1 - 0.0076 16.5 1.3 3.3 7.9 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 EWM27286.1 - 0.027 14.2 0.3 5.2 6.7 0.1 2.6 2 0 0 2 2 2 0 AAA domain Herpes_UL25 PF01499.16 EWM27286.1 - 0.03 12.8 0.1 0.046 12.3 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family NB-ARC PF00931.22 EWM27286.1 - 0.037 13.2 0.3 2.8 7.1 0.2 2.8 2 1 0 2 2 2 0 NB-ARC domain Roc PF08477.13 EWM27286.1 - 0.044 14.0 0.1 9.2 6.5 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 EWM27286.1 - 0.072 12.7 3.7 0.87 9.1 0.5 3.8 3 1 0 3 3 3 0 AAA domain AAA_15 PF13175.6 EWM27286.1 - 0.072 12.8 0.0 5.1 6.7 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.23 EWM27286.1 - 0.25 11.4 0.3 32 4.5 0.1 2.6 2 0 0 2 2 2 0 Dynamin family AAA_22 PF13401.6 EWM27286.1 - 0.33 11.2 3.3 5.2 7.4 0.0 3.3 4 0 0 4 4 3 0 AAA domain AAA_13 PF13166.6 EWM27286.1 - 0.35 9.4 3.3 8.7 4.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain DLIC PF05783.11 EWM27286.1 - 0.57 8.9 10.5 0.75 8.6 0.0 3.0 4 0 0 4 4 4 0 Dynein light intermediate chain (DLIC) AAA_16 PF13191.6 EWM27286.1 - 1.3 9.4 5.7 1.9 8.8 0.0 3.2 2 1 0 2 2 2 0 AAA ATPase domain MRP-L46 PF11788.8 EWM27286.1 - 1.6 9.5 6.4 0.28 11.9 1.4 2.2 3 0 0 3 3 2 0 39S mitochondrial ribosomal protein L46 AAA_18 PF13238.6 EWM27286.1 - 1.6 9.3 7.6 2.6 8.6 0.0 3.3 3 1 0 3 3 3 0 AAA domain AAA_30 PF13604.6 EWM27286.1 - 2.2 7.9 5.4 13 5.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 EWM27286.1 - 7 6.5 5.2 7.8 6.4 0.1 2.3 2 0 0 2 2 2 0 NACHT domain TB2_DP1_HVA22 PF03134.19 EWM27288.1 - 4.8e-13 48.8 3.8 2.6e-05 24.0 0.1 3.6 3 1 0 3 3 3 2 TB2/DP1, HVA22 family YchF-GTPase_C PF06071.13 EWM27290.1 - 5e-38 129.2 1.3 1.5e-37 127.6 0.3 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EWM27290.1 - 1.8e-21 76.3 0.0 1e-20 73.9 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EWM27290.1 - 2.1e-07 30.6 0.0 4.4e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B CHAD PF05235.14 EWM27290.1 - 0.073 13.0 0.0 0.096 12.6 0.0 1.3 1 0 0 1 1 1 0 CHAD domain Roc PF08477.13 EWM27290.1 - 0.11 12.7 0.0 0.67 10.2 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF349 PF03993.12 EWM27290.1 - 0.25 11.6 2.0 0.52 10.6 2.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) CCDC-167 PF15188.6 EWM27290.1 - 1.4 9.4 4.9 0.45 10.9 1.9 1.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 CRAL_TRIO PF00650.20 EWM27291.1 - 1.7e-31 109.1 0.0 2.3e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EWM27291.1 - 3.9e-10 40.0 0.0 5.5e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain JmjC PF02373.22 EWM27292.1 - 1.7e-20 73.5 0.0 5.7e-20 71.9 0.0 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 EWM27292.1 - 1.6e-19 70.6 2.7 1.2e-18 67.8 0.0 2.6 2 1 0 2 2 2 1 Cupin-like domain DUF755 PF05501.11 EWM27292.1 - 0.024 14.9 12.1 0.042 14.1 11.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Cupin_2 PF07883.11 EWM27292.1 - 0.11 12.2 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Cupin domain DUF2347 PF09804.9 EWM27292.1 - 6.7 6.2 5.7 2.7 7.5 3.2 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) Ribosomal_L17 PF01196.19 EWM27294.1 - 1.9e-35 121.6 0.6 2.3e-35 121.3 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L17 Acetyltransf_1 PF00583.25 EWM27295.1 - 6.6e-33 113.4 0.0 5.1e-16 59.0 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EWM27295.1 - 2.3e-21 76.0 0.0 1e-10 41.9 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EWM27295.1 - 5.1e-18 65.2 0.0 4.6e-09 36.3 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EWM27295.1 - 1.3e-14 55.0 0.0 5.1e-06 27.2 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 EWM27295.1 - 3.1e-14 52.7 0.0 6.9e-06 25.9 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_9 PF13527.7 EWM27295.1 - 2.4e-09 37.3 0.1 1.4e-05 25.2 0.0 3.3 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EWM27295.1 - 7.1e-08 32.7 0.0 0.0044 17.2 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EWM27295.1 - 8.4e-07 28.8 0.0 0.036 13.8 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EWM27295.1 - 0.0013 18.8 0.1 2.7 8.2 0.0 2.4 2 0 0 2 2 2 2 GCN5-related N-acetyl-transferase PanZ PF12568.8 EWM27295.1 - 0.0071 16.1 0.1 1.9 8.2 0.0 2.7 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_18 PF18014.1 EWM27295.1 - 0.027 14.3 0.0 1.1 9.1 0.0 2.9 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain ABC_tran PF00005.27 EWM27296.1 - 1.9e-43 148.3 0.2 3.1e-21 76.3 0.0 3.0 3 1 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EWM27296.1 - 5.4e-25 87.2 2.6 5.4e-25 87.2 2.6 3.5 5 0 0 5 5 3 1 ABC transporter AAA_21 PF13304.6 EWM27296.1 - 1e-17 64.9 10.0 7.3e-06 26.0 0.1 4.8 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EWM27296.1 - 1.4e-13 50.8 1.2 5e-05 22.8 0.0 3.5 2 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EWM27296.1 - 1.7e-08 35.1 1.0 0.0037 17.7 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.6 EWM27296.1 - 1.8e-06 28.3 0.2 0.0025 18.1 0.2 2.9 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EWM27296.1 - 3.2e-06 27.4 0.7 0.094 13.0 0.1 3.1 2 2 0 2 2 2 2 AAA domain NACHT PF05729.12 EWM27296.1 - 1.1e-05 25.4 0.0 0.024 14.6 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_29 PF13555.6 EWM27296.1 - 4.4e-05 23.1 0.1 0.07 12.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain NB-ARC PF00931.22 EWM27296.1 - 5.1e-05 22.6 0.1 0.23 10.6 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain RsgA_GTPase PF03193.16 EWM27296.1 - 0.00015 21.8 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 EWM27296.1 - 0.0002 21.4 0.0 0.025 14.7 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.6 EWM27296.1 - 0.00073 19.3 0.0 1.2 8.8 0.0 3.4 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.6 EWM27296.1 - 0.0011 19.2 0.1 0.086 13.1 0.0 3.5 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 EWM27296.1 - 0.0012 19.1 0.3 3.8 7.7 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_24 PF13479.6 EWM27296.1 - 0.0012 18.6 0.1 0.57 9.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EWM27296.1 - 0.0013 18.8 0.9 3.3 7.8 0.2 3.9 4 1 0 4 4 3 1 AAA domain MeaB PF03308.16 EWM27296.1 - 0.0021 17.1 0.1 0.47 9.4 0.0 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 EWM27296.1 - 0.0027 17.7 0.9 4.9 7.2 0.0 4.2 5 0 0 5 5 4 0 AAA domain (dynein-related subfamily) AAA PF00004.29 EWM27296.1 - 0.0047 17.4 0.0 4.9 7.6 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EWM27296.1 - 0.0063 16.9 0.7 6.3 7.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 EWM27296.1 - 0.0064 16.2 11.4 0.88 9.2 0.8 4.4 3 2 1 5 5 5 2 AAA ATPase domain cobW PF02492.19 EWM27296.1 - 0.0067 16.0 0.3 2.1 7.9 0.1 2.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 EWM27296.1 - 0.0074 16.7 0.1 9 6.7 0.0 3.2 2 1 1 3 3 3 0 RNA helicase AAA_18 PF13238.6 EWM27296.1 - 0.0085 16.6 5.6 2.4 8.7 0.0 4.2 6 0 0 6 6 4 1 AAA domain NTPase_1 PF03266.15 EWM27296.1 - 0.0088 16.0 0.1 4.2 7.2 0.0 2.8 2 0 0 2 2 2 1 NTPase DUF87 PF01935.17 EWM27296.1 - 0.0095 16.0 2.8 0.046 13.8 0.0 3.3 4 0 0 4 4 3 1 Helicase HerA, central domain MobB PF03205.14 EWM27296.1 - 0.028 14.3 0.1 11 5.9 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.6 EWM27296.1 - 0.03 13.9 0.2 2 7.9 0.0 2.9 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EWM27296.1 - 0.056 12.7 0.0 0.31 10.3 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin Roc PF08477.13 EWM27296.1 - 0.075 13.3 0.0 17 5.6 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase KAP_NTPase PF07693.14 EWM27296.1 - 0.078 12.2 0.8 1.7 7.8 0.0 2.9 3 1 0 3 3 3 0 KAP family P-loop domain AAA_27 PF13514.6 EWM27296.1 - 0.091 12.3 3.3 0.2 11.2 0.0 2.7 3 0 0 3 3 2 0 AAA domain ATPase_2 PF01637.18 EWM27296.1 - 0.15 12.0 1.5 14 5.5 0.0 2.9 3 1 0 3 3 2 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 EWM27296.1 - 0.16 12.5 20.5 0.16 12.4 0.0 4.3 3 1 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 EWM27296.1 - 0.22 11.6 0.0 0.22 11.6 0.0 3.2 3 1 0 3 3 2 0 Dynamin family AAA_17 PF13207.6 EWM27296.1 - 4.9 7.6 7.2 19 5.7 0.2 3.3 4 0 0 4 4 2 0 AAA domain ATP-grasp_4 PF13535.6 EWM27297.1 - 3.4e-11 43.0 0.0 6e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 EWM27297.1 - 1.3e-07 31.6 0.0 2.1e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 EWM27297.1 - 1.4e-06 28.5 0.0 2.4e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 EWM27297.1 - 0.00065 19.5 0.0 0.029 14.1 0.0 2.5 3 0 0 3 3 3 1 ATP-grasp in the biosynthetic pathway with Ter operon GSH-S_ATP PF02955.16 EWM27297.1 - 0.048 13.1 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain LAL_C2 PF18603.1 EWM27297.1 - 0.11 12.7 0.0 1.8 8.8 0.0 2.4 2 0 0 2 2 2 0 L-amino acid ligase C-terminal domain 2 DNA_pol_D_N PF18018.1 EWM27298.1 - 6.4e-32 110.4 0.0 9.6e-32 109.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 EWM27299.1 - 8.4e-33 113.5 2.1 1.1e-32 113.1 2.1 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Mt_ATP-synt_D PF05873.12 EWM27301.1 - 4.5e-12 46.1 3.6 6e-12 45.7 3.6 1.2 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Bap31_Bap29_C PF18035.1 EWM27301.1 - 0.016 15.2 0.0 0.051 13.6 0.0 1.8 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Apyrase PF06079.11 EWM27305.1 - 1.3e-35 123.0 0.0 1.7e-35 122.7 0.0 1.0 1 0 0 1 1 1 1 Apyrase RNA_pol_Rpo13 PF12136.8 EWM27306.1 - 3.4e-05 23.6 12.2 0.023 14.6 5.7 2.8 2 0 0 2 2 2 2 RNA polymerase Rpo13 subunit HTH domain Glyoxalase_6 PF18029.1 EWM27306.1 - 0.0052 17.5 0.1 0.0052 17.5 0.1 2.4 2 0 0 2 2 2 1 Glyoxalase-like domain CPSF_A PF03178.15 EWM27308.1 - 4.8e-23 82.0 0.0 7.3e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 CPSF A subunit region DUF547 PF04784.14 EWM27309.1 - 7.5e-05 22.8 0.0 0.0001 22.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF547 Pkinase PF00069.25 EWM27310.1 - 2.4e-28 99.2 0.0 4.3e-17 62.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EWM27310.1 - 3e-18 66.0 0.0 1.9e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EWM27310.1 - 0.00061 19.8 0.1 0.67 9.8 0.0 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EWM27310.1 - 0.03 13.1 0.0 0.054 12.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase MMS1_N PF10433.9 EWM27312.1 - 1.6e-10 40.3 0.0 2e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Cpn60_TCP1 PF00118.24 EWM27313.1 - 3.3e-28 98.6 0.2 6.8e-28 97.5 0.2 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Aa_trans PF01490.18 EWM27314.1 - 2.4e-62 211.0 7.1 2.7e-33 115.3 0.2 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EWM27314.1 - 0.00011 21.4 0.9 0.00011 21.4 0.9 2.7 3 0 0 3 3 3 2 Tryptophan/tyrosine permease family Cpn60_TCP1 PF00118.24 EWM27315.1 - 1.7e-35 122.6 1.1 5.4e-35 121.0 1.1 1.7 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF4400 PF14348.6 EWM27315.1 - 0.15 11.6 0.8 0.56 9.7 0.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4400) Myb_DNA-binding PF00249.31 EWM27317.1 - 1.1e-06 28.7 0.8 1.1e-06 28.7 0.8 2.5 2 1 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EWM27318.1 - 4.8e-13 49.1 4.5 1.1e-06 28.7 2.5 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EWM27318.1 - 9.9e-10 38.5 1.2 2.7e-07 30.7 0.6 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Peptidase_M3_N PF08439.10 EWM27318.1 - 0.052 13.8 0.1 0.2 11.9 0.0 1.9 2 0 0 2 2 2 0 Oligopeptidase F DAO PF01266.24 EWM27319.1 - 2.3e-51 175.5 0.8 2.8e-51 175.2 0.8 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EWM27319.1 - 8.9e-05 22.6 1.6 0.0019 18.4 0.3 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EWM27319.1 - 0.00025 20.4 0.5 0.0024 17.2 0.4 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EWM27319.1 - 0.00034 20.0 0.0 0.0006 19.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 EWM27319.1 - 0.011 15.4 0.4 0.02 14.5 0.4 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA LDcluster4 PF18306.1 EWM27319.1 - 0.018 14.6 0.8 0.028 14.0 0.1 1.6 2 0 0 2 2 2 0 SLOG cluster4 family Thi4 PF01946.17 EWM27319.1 - 0.054 12.7 0.5 0.054 12.7 0.5 1.8 3 0 0 3 3 3 0 Thi4 family tRNA_Me_trans PF03054.16 EWM27320.1 - 3.9e-94 315.4 0.0 6.2e-94 314.7 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase SufE PF02657.15 EWM27320.1 - 3.5e-17 62.4 0.0 5.5e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Fe-S metabolism associated domain Asn_synthase PF00733.21 EWM27320.1 - 0.0013 18.5 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase ThiI PF02568.14 EWM27320.1 - 0.0074 15.9 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 EWM27320.1 - 0.074 12.5 0.0 0.22 11.0 0.0 1.7 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Lysine_decarbox PF03641.14 EWM27321.1 - 1.2e-25 90.1 0.0 4.2e-25 88.4 0.0 1.8 2 0 0 2 2 2 1 Possible lysine decarboxylase LDcluster4 PF18306.1 EWM27321.1 - 4e-08 33.0 0.0 7.2e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 SLOG cluster4 family TPX2 PF06886.11 EWM27321.1 - 0.15 12.4 0.8 0.39 11.0 0.8 1.6 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) Lysine_decarbox PF03641.14 EWM27322.1 - 8.7e-23 80.9 0.1 3.2e-22 79.0 0.0 1.8 2 0 0 2 2 2 1 Possible lysine decarboxylase LDcluster4 PF18306.1 EWM27322.1 - 4.1e-08 33.0 0.0 7.6e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 SLOG cluster4 family Retrotrans_gag PF03732.17 EWM27322.1 - 0.066 13.5 0.4 0.13 12.6 0.4 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein TPX2 PF06886.11 EWM27322.1 - 0.14 12.4 0.8 0.37 11.0 0.8 1.6 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) RVT_N PF13655.6 EWM27323.1 - 0.42 10.9 3.4 3.3 8.0 0.2 3.4 3 1 0 3 3 3 0 N-terminal domain of reverse transcriptase GBP_C PF02841.14 EWM27323.1 - 8.1 5.7 48.6 5.4 6.3 20.8 2.7 1 1 1 2 2 2 0 Guanylate-binding protein, C-terminal domain Homeobox_KN PF05920.11 EWM27325.1 - 1.5e-13 50.4 0.2 2.4e-13 49.7 0.2 1.3 1 0 0 1 1 1 1 Homeobox KN domain zf-RING_2 PF13639.6 EWM27325.1 - 1.9e-08 34.5 6.5 3.5e-08 33.7 6.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EWM27325.1 - 1e-05 25.3 4.3 1.7e-05 24.6 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EWM27325.1 - 7.2e-05 23.0 5.2 0.00017 21.8 5.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EWM27325.1 - 9e-05 22.2 6.4 9e-05 22.2 6.4 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Homeodomain PF00046.29 EWM27325.1 - 0.0001 22.1 0.3 0.00022 21.0 0.0 1.7 2 0 0 2 2 2 1 Homeodomain zf-C3HC4_3 PF13920.6 EWM27325.1 - 0.00012 21.9 4.5 0.00018 21.3 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EWM27325.1 - 0.00026 21.0 3.9 0.00052 20.0 3.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EWM27325.1 - 0.00027 20.8 7.6 0.00076 19.3 7.7 1.6 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 EWM27325.1 - 0.056 13.1 1.8 0.097 12.3 0.9 1.8 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 EWM27325.1 - 0.062 13.3 3.9 0.23 11.4 4.1 1.8 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_11 PF17123.5 EWM27325.1 - 0.072 12.8 0.2 0.072 12.8 0.2 2.0 2 0 0 2 2 1 0 RING-like zinc finger RINGv PF12906.7 EWM27325.1 - 0.1 12.7 0.2 0.22 11.6 0.2 1.5 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.29 EWM27325.1 - 0.97 9.4 3.3 1.7 8.6 3.3 1.4 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 EWM27325.1 - 4 7.7 5.7 1.9 8.7 1.5 2.4 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.6 EWM27325.1 - 6.9 6.8 14.8 0.049 13.7 3.3 2.3 2 0 0 2 2 2 0 RING-type zinc-finger TIP120 PF08623.10 EWM27326.1 - 1.3e-34 119.4 0.1 6.2e-33 113.9 0.0 3.4 4 0 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT PF02985.22 EWM27326.1 - 2.2e-10 39.9 12.2 0.085 13.2 0.0 8.7 9 0 0 9 9 8 2 HEAT repeat HEAT_2 PF13646.6 EWM27326.1 - 8.4e-10 38.9 19.8 0.0095 16.3 0.1 7.8 6 1 2 8 8 8 4 HEAT repeats HEAT_EZ PF13513.6 EWM27326.1 - 1.6e-07 31.7 30.7 0.076 13.5 0.1 10.9 11 2 1 12 12 12 3 HEAT-like repeat Adaptin_N PF01602.20 EWM27326.1 - 2e-06 26.6 0.2 0.21 10.1 0.2 5.1 4 1 1 5 5 5 2 Adaptin N terminal region Tti2 PF10521.9 EWM27326.1 - 0.00019 21.1 0.2 0.5 9.9 0.0 4.0 4 0 0 4 4 4 1 Tti2 family RTP1_C1 PF10363.9 EWM27326.1 - 0.0025 18.0 5.2 62 3.8 0.1 6.7 7 0 0 7 7 7 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_UF PF18817.1 EWM27326.1 - 0.016 15.5 0.0 0.05 13.9 0.0 1.8 1 0 0 1 1 1 0 Repeat of uncharacterized protein PH0542 DRIM PF07539.12 EWM27326.1 - 0.027 12.8 2.5 0.28 9.4 0.0 3.5 4 1 0 4 4 4 0 Down-regulated in metastasis DUF3385 PF11865.8 EWM27326.1 - 0.056 13.3 0.0 1.2e+02 2.5 0.0 5.0 5 1 0 5 5 5 0 Domain of unknown function (DUF3385) HEAT_PBS PF03130.16 EWM27326.1 - 1.9 9.4 10.1 42 5.2 0.1 5.9 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Radial_spoke PF04712.12 EWM27326.1 - 5 5.9 5.1 20 4.0 5.9 1.5 2 0 0 2 2 2 0 Radial spokehead-like protein ClpS PF02617.17 EWM27327.1 - 2e-11 43.5 0.0 3.6e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS PknG_TPR PF16918.5 EWM27327.1 - 0.0017 17.2 0.1 0.0023 16.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase G tetratricopeptide repeat DUF4512 PF14975.6 EWM27328.1 - 0.16 12.7 1.0 0.33 11.7 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) MCM PF00493.23 EWM27329.1 - 4.4e-97 323.6 0.0 3.5e-84 281.4 0.0 2.3 2 0 0 2 2 2 2 MCM P-loop domain MCM_OB PF17207.3 EWM27329.1 - 5.1e-35 120.1 0.1 8.3e-35 119.4 0.1 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EWM27329.1 - 1.3e-26 92.8 0.0 2.6e-26 91.8 0.0 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 EWM27329.1 - 1.3e-08 34.5 0.1 3.7e-05 23.2 0.0 3.1 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EWM27329.1 - 1.1e-06 28.6 0.1 5.8e-06 26.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EWM27329.1 - 0.00022 21.1 0.0 0.001 18.9 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EWM27329.1 - 0.15 11.8 0.0 16 5.2 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Asp PF00026.23 EWM27330.1 - 1.2e-32 113.6 0.0 4.5e-32 111.7 0.0 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EWM27330.1 - 4e-22 79.3 0.6 4e-22 79.3 0.6 2.2 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EWM27330.1 - 1.8e-13 50.6 0.0 1.8e-12 47.4 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Atx10homo_assoc PF09759.9 EWM27331.1 - 8.3e-30 102.7 0.5 2.9e-29 101.0 0.1 2.2 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain TFIID_20kDa PF03847.13 EWM27332.1 - 2.3e-15 56.9 0.0 2.8e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TFIID-18kDa PF02269.16 EWM27332.1 - 0.0066 16.5 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-T_C PF15511.6 EWM27332.1 - 0.014 15.5 0.0 0.018 15.2 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 EWM27332.1 - 0.043 14.1 0.0 0.062 13.6 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Asp_protease_2 PF13650.6 EWM27333.1 - 8.8e-16 58.3 6.3 0.0034 18.0 0.1 4.6 4 0 0 4 4 4 4 Aspartyl protease gag-asp_proteas PF13975.6 EWM27333.1 - 2.7e-10 40.7 1.2 0.021 15.4 0.0 5.0 4 1 0 4 4 4 4 gag-polyprotein putative aspartyl protease Metallophos PF00149.28 EWM27334.1 - 2.2e-32 113.2 0.0 2.8e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EWM27334.1 - 7.5e-17 61.5 0.4 1.4e-16 60.6 0.4 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain DUF410 PF04190.13 EWM27335.1 - 2.6e-23 83.1 0.0 1.4e-20 74.2 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF410) TPR_7 PF13176.6 EWM27335.1 - 0.087 12.9 1.1 1.3 9.2 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_transf_34 PF05637.12 EWM27337.1 - 1.3e-05 25.1 1.0 0.94 9.1 0.8 3.1 3 0 0 3 3 3 3 galactosyl transferase GMA12/MNN10 family 4HBT PF03061.22 EWM27338.1 - 2e-07 31.3 0.1 0.00031 21.1 0.0 2.5 2 0 0 2 2 2 2 Thioesterase superfamily Methyltransf_16 PF10294.9 EWM27339.1 - 5.9e-27 94.5 0.0 8.3e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase DUF938 PF06080.12 EWM27339.1 - 0.0027 17.5 0.0 0.0041 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_23 PF13489.6 EWM27339.1 - 0.0047 16.8 0.0 0.011 15.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Hema_esterase PF03996.15 EWM27339.1 - 0.021 14.6 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Hemagglutinin esterase MTS PF05175.14 EWM27339.1 - 0.065 12.8 0.0 0.092 12.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 EWM27339.1 - 0.075 13.8 0.0 0.48 11.2 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain DSPc PF00782.20 EWM27340.1 - 2.1e-28 98.8 0.0 3.8e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EWM27340.1 - 0.002 17.7 0.0 0.003 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Acyl_transf_3 PF01757.22 EWM27341.1 - 7.4e-19 68.0 37.2 7.4e-19 68.0 37.2 1.8 2 0 0 2 2 2 1 Acyltransferase family OAD_gamma PF04277.13 EWM27341.1 - 0.2 12.2 1.2 0.58 10.8 0.0 2.4 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DUF308 PF03729.13 EWM27341.1 - 0.37 11.1 4.1 0.77 10.1 0.4 3.1 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) Scs3p PF10261.9 EWM27345.1 - 0.025 14.1 0.4 0.038 13.5 0.4 1.3 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM DUF5134 PF17197.4 EWM27345.1 - 2.2 8.2 4.9 6 6.8 1.4 3.1 2 1 2 4 4 4 0 Domain of unknown function (DUF5134) Rrn6 PF10214.9 EWM27347.1 - 0.00082 18.0 12.7 0.001 17.7 12.7 1.2 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor MCM_bind PF09739.9 EWM27347.1 - 0.0025 16.3 1.1 0.0032 16.0 1.1 1.0 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor DUF1645 PF07816.11 EWM27347.1 - 0.003 18.2 11.3 0.003 18.2 11.3 1.4 2 0 0 2 2 1 1 Protein of unknown function (DUF1645) SR-25 PF10500.9 EWM27347.1 - 0.0067 16.1 24.5 0.01 15.4 24.5 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein GREB1 PF15782.5 EWM27347.1 - 0.038 11.1 5.3 0.044 10.9 5.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TEX19 PF15553.6 EWM27347.1 - 0.099 12.6 0.6 0.16 11.9 0.6 1.4 1 0 0 1 1 1 0 Testis-expressed protein 19 Macoilin PF09726.9 EWM27347.1 - 0.17 10.4 9.0 0.2 10.2 9.0 1.0 1 0 0 1 1 1 0 Macoilin family DUF755 PF05501.11 EWM27347.1 - 0.22 11.8 23.9 0.34 11.2 23.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) SPX PF03105.19 EWM27347.1 - 0.41 10.5 12.2 0.55 10.1 12.2 1.2 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 EWM27347.1 - 0.49 9.2 10.5 0.56 9.0 10.5 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1635 PF07795.11 EWM27347.1 - 0.65 9.8 7.2 1.1 9.1 7.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) PI3K_1B_p101 PF10486.9 EWM27347.1 - 0.65 7.7 11.8 0.82 7.4 11.8 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit BUD22 PF09073.10 EWM27347.1 - 1.1 8.5 13.6 1.5 8.1 13.6 1.1 1 0 0 1 1 1 0 BUD22 Presenilin PF01080.17 EWM27347.1 - 1.2 7.8 4.7 1.5 7.5 4.7 1.1 1 0 0 1 1 1 0 Presenilin Lin-8 PF03353.15 EWM27347.1 - 2.2 7.8 8.9 2.8 7.4 8.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RAP1 PF07218.11 EWM27347.1 - 2.2 6.4 11.2 2.6 6.2 11.2 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) bZIP_Maf PF03131.17 EWM27349.1 - 1.1e-05 25.9 8.2 2.7e-05 24.6 8.2 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.21 EWM27349.1 - 4.3e-05 23.5 14.3 0.0012 18.9 15.0 2.1 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EWM27349.1 - 0.0011 19.0 11.2 0.0019 18.3 11.2 1.3 1 0 0 1 1 1 1 Basic region leucine zipper GAS PF13851.6 EWM27349.1 - 0.29 10.5 8.0 0.43 9.9 8.0 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Macoilin PF09726.9 EWM27349.1 - 1.3 7.5 5.8 2.1 6.8 5.8 1.2 1 0 0 1 1 1 0 Macoilin family DUF218 PF02698.17 EWM27350.1 - 0.00021 21.3 1.2 0.0017 18.3 1.2 2.1 1 1 0 1 1 1 1 DUF218 domain Apolipoprotein PF01442.18 EWM27351.1 - 3.3e-06 27.1 21.0 3.9e-05 23.6 9.5 2.6 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 EWM27351.1 - 0.0012 19.4 24.9 0.045 14.4 0.4 3.9 1 1 1 3 3 3 3 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 EWM27351.1 - 0.013 16.1 33.4 1.8e+04 -13.3 33.4 4.6 1 1 0 1 1 0 0 YtxH-like protein BshC PF10079.9 EWM27351.1 - 0.066 12.0 5.9 4 6.1 0.0 2.0 1 1 1 2 2 2 0 Bacillithiol biosynthesis BshC ApoLp-III PF07464.11 EWM27351.1 - 0.097 12.8 16.7 0.58 10.2 10.2 2.8 1 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF4170 PF13773.6 EWM27351.1 - 0.45 10.7 3.2 1.2 9.4 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4170) REF PF05755.12 EWM27351.1 - 1.1 9.0 15.4 7.3 6.3 7.0 3.1 1 1 0 2 2 2 0 Rubber elongation factor protein (REF) POTRA_TamA_1 PF17243.2 EWM27351.1 - 1.2 9.2 7.5 6.3 7.0 0.3 2.7 3 0 0 3 3 3 0 POTRA domain TamA domain 1 DUF948 PF06103.11 EWM27351.1 - 1.6 9.0 8.5 5.7 7.3 0.1 3.3 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Mt_ATP-synt_B PF05405.14 EWM27351.1 - 6.4 6.4 10.4 9.9 5.8 0.1 2.6 1 1 2 3 3 3 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Oleosin PF01277.17 EWM27351.1 - 9.1 6.1 11.3 24 4.7 1.2 3.5 2 1 1 3 3 3 0 Oleosin DUF4203 PF13886.6 EWM27352.1 - 5.5e-19 68.6 22.7 9.5e-19 67.9 22.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Dpy19 PF10034.9 EWM27352.1 - 0.12 10.6 2.2 0.13 10.4 2.2 1.3 1 0 0 1 1 1 0 Q-cell neuroblast polarisation Presenilin PF01080.17 EWM27352.1 - 0.33 9.7 8.4 0.7 8.6 8.4 1.6 1 0 0 1 1 1 0 Presenilin FAM176 PF14851.6 EWM27352.1 - 0.54 9.9 1.6 4.7 6.9 0.1 2.6 3 0 0 3 3 3 0 FAM176 family TFIIA PF03153.13 EWM27354.1 - 0.022 14.7 3.8 0.023 14.7 3.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 EWM27354.1 - 0.21 11.2 6.7 0.26 10.9 6.7 1.1 1 0 0 1 1 1 0 Spt20 family PNISR PF15996.5 EWM27354.1 - 0.25 11.6 8.0 0.38 11.0 8.0 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Presenilin PF01080.17 EWM27354.1 - 0.91 8.2 1.4 0.94 8.2 1.4 1.1 1 0 0 1 1 1 0 Presenilin Synaphin PF05835.12 EWM27354.1 - 2.5 8.4 9.9 0.2 12.0 2.5 2.6 3 0 0 3 3 3 0 Synaphin protein DUF962 PF06127.11 EWM27358.1 - 1.7e-27 95.3 1.0 1.2e-26 92.6 1.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF962) TMEM43 PF07787.12 EWM27358.1 - 1 8.7 4.3 0.64 9.4 1.5 1.8 2 0 0 2 2 2 0 Transmembrane protein 43 DUF983 PF06170.12 EWM27358.1 - 1.8 9.0 0.0 1.8 9.0 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF983) Acyl_transf_3 PF01757.22 EWM27359.1 - 2.1e-16 60.0 39.8 2.8e-09 36.5 31.7 2.7 2 1 0 2 2 2 2 Acyltransferase family PAP_fibrillin PF04755.12 EWM27360.1 - 7.8e-07 29.2 0.0 1e-06 28.9 0.0 1.1 1 0 0 1 1 1 1 PAP_fibrillin CoA_trans PF01144.23 EWM27361.1 - 1.3e-08 34.5 0.0 1.4e-08 34.4 0.0 1.0 1 0 0 1 1 1 1 Coenzyme A transferase CoA_trans PF01144.23 EWM27362.1 - 1.8e-85 285.7 0.0 2.1e-76 256.1 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AhpC-TSA PF00578.21 EWM27365.1 - 1.3e-33 115.5 0.1 1.6e-33 115.3 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EWM27365.1 - 4.6e-19 68.6 0.1 5.9e-19 68.2 0.1 1.1 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.14 EWM27365.1 - 0.013 15.4 0.1 0.023 14.6 0.1 1.4 1 1 0 1 1 1 0 SCO1/SenC Lectin_leg-like PF03388.13 EWM27367.1 - 1.3e-33 116.3 0.1 1.6e-33 116.0 0.1 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 EWM27367.1 - 1.7e-07 31.5 0.2 2.4e-07 31.0 0.2 1.1 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 EWM27367.1 - 4.6e-06 26.4 0.0 1e-05 25.2 0.0 1.6 1 1 0 1 1 1 1 Legume lectin domain AAA PF00004.29 EWM27368.1 - 1.3e-20 74.2 0.0 2.4e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EWM27368.1 - 7.4e-08 32.5 0.0 2.4e-07 30.8 0.0 1.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EWM27368.1 - 0.00026 21.3 0.4 0.047 14.0 0.1 3.5 2 2 1 3 3 3 1 AAA domain AAA_PrkA PF08298.11 EWM27368.1 - 0.00051 19.1 0.0 0.0017 17.3 0.0 1.8 2 0 0 2 2 2 1 PrkA AAA domain AAA_16 PF13191.6 EWM27368.1 - 0.00061 20.2 0.1 0.00061 20.2 0.1 2.5 2 2 0 2 2 2 1 AAA ATPase domain LON_substr_bdg PF02190.16 EWM27368.1 - 0.0011 18.9 0.8 0.0014 18.6 0.1 1.5 2 0 0 2 2 1 1 ATP-dependent protease La (LON) substrate-binding domain RuvB_N PF05496.12 EWM27368.1 - 0.0035 17.1 0.0 0.011 15.5 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain RsgA_GTPase PF03193.16 EWM27368.1 - 0.0069 16.3 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_3 PF07726.11 EWM27368.1 - 0.0092 15.8 0.0 0.032 14.1 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EWM27368.1 - 0.014 15.9 5.2 0.077 13.5 0.0 2.4 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.6 EWM27368.1 - 0.014 16.0 0.4 0.037 14.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EWM27368.1 - 0.016 15.1 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.17 EWM27368.1 - 0.018 14.8 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 EWM27368.1 - 0.021 15.0 1.3 0.046 13.9 0.0 2.2 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 EWM27368.1 - 0.041 14.3 0.0 0.17 12.3 0.0 1.9 2 0 0 2 2 2 0 RNA helicase TsaE PF02367.17 EWM27368.1 - 0.081 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SKI PF01202.22 EWM27368.1 - 0.088 12.9 1.8 0.26 11.4 0.1 2.2 2 0 0 2 2 2 0 Shikimate kinase SMC_N PF02463.19 EWM27368.1 - 0.13 11.7 0.0 3.2 7.1 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ABC_tran PF00005.27 EWM27368.1 - 0.19 12.2 1.0 1.2 9.6 0.1 2.2 2 0 0 2 2 2 0 ABC transporter AAA_11 PF13086.6 EWM27368.1 - 0.79 9.5 2.9 8.7 6.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain CPBP PF02517.16 EWM27369.1 - 3.1e-11 43.5 1.4 3.1e-11 43.5 1.4 1.8 2 0 0 2 2 2 1 CPBP intramembrane metalloprotease Lon_C PF05362.13 EWM27370.1 - 2.2e-72 242.9 1.6 2.8e-48 164.2 0.5 2.1 2 0 0 2 2 2 2 Lon protease (S16) C-terminal proteolytic domain ChlI PF13541.6 EWM27370.1 - 7.8e-07 29.0 0.0 3.7e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase Birna_VP4 PF01768.16 EWM27370.1 - 0.011 15.5 0.2 0.028 14.2 0.1 1.6 2 0 0 2 2 2 0 Birnavirus VP4 protein ABC_membrane PF00664.23 EWM27371.1 - 5.6e-61 206.6 15.7 4.4e-31 108.5 2.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EWM27371.1 - 8e-08 32.9 0.0 1.7e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EWM27372.1 - 4.4e-47 161.0 9.6 5.8e-31 108.1 1.9 2.4 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EWM27372.1 - 1.4e-39 135.7 0.0 4.9e-29 101.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EWM27372.1 - 9.4e-07 28.5 0.0 0.047 13.1 0.0 3.0 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EWM27372.1 - 3.7e-05 23.7 0.4 0.079 12.7 0.0 3.2 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EWM27372.1 - 0.0013 18.9 0.5 2.3 8.5 0.0 3.3 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 EWM27372.1 - 0.046 13.8 0.2 0.1 12.7 0.2 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF2427 PF10348.9 EWM27373.1 - 1.4 8.8 4.2 0.77 9.6 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) OTU PF02338.19 EWM27374.1 - 7.4e-26 91.1 0.1 1.3e-25 90.3 0.0 1.4 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EWM27374.1 - 4e-05 23.2 0.0 0.05 13.1 0.0 2.2 1 1 0 2 2 2 2 Peptidase C65 Otubain OHA PF14418.6 EWM27374.1 - 0.049 13.4 0.0 0.096 12.5 0.0 1.4 1 0 0 1 1 1 0 OST-HTH Associated domain Mu-like_Pro PF10123.9 EWM27374.1 - 0.095 12.2 1.5 0.13 11.8 1.5 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein NINJA_B PF16136.5 EWM27374.1 - 0.97 9.8 6.2 1.6 9.1 6.2 1.3 1 0 0 1 1 1 0 Putative nuclear localisation signal Pex14_N PF04695.13 EWM27375.1 - 0.00021 22.0 13.1 0.00025 21.7 13.1 1.2 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2722 PF10846.8 EWM27375.1 - 0.00072 18.6 13.7 0.00078 18.5 13.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) CCDC53 PF10152.9 EWM27375.1 - 0.0098 16.3 5.4 0.012 16.1 5.4 1.2 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex Presenilin PF01080.17 EWM27375.1 - 0.05 12.4 2.6 0.063 12.0 2.6 1.2 1 0 0 1 1 1 0 Presenilin Suf PF05843.14 EWM27375.1 - 0.087 12.8 10.8 0.1 12.6 10.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Hydin_ADK PF17213.3 EWM27375.1 - 0.25 11.6 2.7 0.35 11.1 2.7 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain SpoIIP PF07454.11 EWM27375.1 - 0.29 10.6 4.3 0.34 10.3 4.3 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) TFIIA PF03153.13 EWM27375.1 - 0.57 10.1 29.2 0.73 9.8 29.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2076 PF09849.9 EWM27375.1 - 0.81 9.7 26.0 0.99 9.4 26.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Rrn6 PF10214.9 EWM27375.1 - 2 6.8 14.5 2.3 6.6 14.5 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Lin-8 PF03353.15 EWM27375.1 - 2 7.9 12.8 2.6 7.5 12.8 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PepSY_TM PF03929.16 EWM27375.1 - 2.3 7.8 5.5 2.7 7.6 5.5 1.1 1 0 0 1 1 1 0 PepSY-associated TM region eIF-3_zeta PF05091.12 EWM27375.1 - 2.7 6.8 9.5 3.2 6.6 9.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAT1 PF09770.9 EWM27375.1 - 3.1 5.9 17.8 3.8 5.7 17.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.16 EWM27375.1 - 3.8 7.5 4.3 4.5 7.3 4.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CobT PF06213.12 EWM27375.1 - 8.2 5.7 12.5 10 5.4 12.5 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CAP PF00188.26 EWM27382.1 - 0.018 15.9 0.1 0.031 15.1 0.1 1.4 1 0 0 1 1 1 0 Cysteine-rich secretory protein family BUD22 PF09073.10 EWM27382.1 - 0.22 10.8 30.3 0.25 10.6 30.3 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 EWM27382.1 - 1.8 7.9 37.8 2.1 7.7 37.8 1.2 1 0 0 1 1 1 0 SDA1 Peptidase_C14 PF00656.22 EWM27383.1 - 1.8e-31 110.0 0.0 2.8e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 Caspase domain NOT2_3_5 PF04153.18 EWM27383.1 - 6.1e-08 32.8 7.1 1.8e-07 31.3 6.1 2.1 2 1 0 2 2 2 1 NOT2 / NOT3 / NOT5 family HSP33 PF01430.19 EWM27383.1 - 0.92 8.9 3.1 0.26 10.7 0.1 1.6 2 0 0 2 2 2 0 Hsp33 protein Metallophos PF00149.28 EWM27385.1 - 2e-15 57.8 0.1 3.2e-15 57.2 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 EWM27385.1 - 1.6e-12 48.1 0.0 4e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C fn3_PAP PF17808.1 EWM27385.1 - 2.2e-12 47.1 0.0 1.9e-11 44.1 0.0 2.3 1 1 0 1 1 1 1 Fn3-like domain from Purple Acid Phosphatase Pur_ac_phosph_N PF16656.5 EWM27385.1 - 2.1e-11 44.3 0.0 1.6e-10 41.4 0.0 2.4 1 1 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain PP2C PF00481.21 EWM27389.1 - 5.8e-76 255.5 0.1 2.1e-59 201.2 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 EWM27389.1 - 0.044 13.7 0.0 4 7.3 0.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) DGF-1_C PF11040.8 EWM27389.1 - 2.1 8.4 6.1 3.3 7.8 0.2 3.2 3 0 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus BUD22 PF09073.10 EWM27390.1 - 0.0083 15.5 28.3 0.011 15.1 28.3 1.2 1 0 0 1 1 1 1 BUD22 NPR3 PF03666.13 EWM27390.1 - 0.012 14.4 6.6 0.016 14.0 6.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CAP PF00188.26 EWM27390.1 - 0.014 16.2 0.1 0.027 15.3 0.1 1.4 1 0 0 1 1 1 0 Cysteine-rich secretory protein family SDA1 PF05285.12 EWM27390.1 - 0.043 13.2 36.7 0.062 12.7 36.7 1.2 1 0 0 1 1 1 0 SDA1 SAPS PF04499.15 EWM27390.1 - 0.67 8.7 12.9 0.75 8.5 12.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2076 PF09849.9 EWM27390.1 - 0.86 9.6 25.5 1.2 9.1 25.5 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF2786 PF10979.8 EWM27390.1 - 1.2 9.1 6.6 5.3 7.0 3.8 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2786) Mpp10 PF04006.12 EWM27390.1 - 1.6 7.1 25.6 2.1 6.7 25.6 1.1 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 EWM27390.1 - 2.2 6.4 40.0 2.9 6.0 40.0 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 EWM27390.1 - 4.9 5.1 47.8 7.4 4.5 47.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF913 PF06025.12 EWM27390.1 - 5.1 6.0 6.3 7.3 5.5 6.3 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Afi1 PF07792.12 EWM27390.1 - 5.1 7.6 17.7 12 6.4 17.7 1.6 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Presenilin PF01080.17 EWM27390.1 - 5.6 5.6 6.4 7 5.3 6.4 1.1 1 0 0 1 1 1 0 Presenilin BUD22 PF09073.10 EWM27391.1 - 0.0084 15.5 28.3 0.011 15.1 28.3 1.2 1 0 0 1 1 1 1 BUD22 NPR3 PF03666.13 EWM27391.1 - 0.012 14.4 6.6 0.017 14.0 6.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CAP PF00188.26 EWM27391.1 - 0.014 16.2 0.1 0.027 15.3 0.1 1.5 1 0 0 1 1 1 0 Cysteine-rich secretory protein family SDA1 PF05285.12 EWM27391.1 - 0.044 13.2 36.7 0.063 12.7 36.7 1.2 1 0 0 1 1 1 0 SDA1 SAPS PF04499.15 EWM27391.1 - 0.68 8.7 12.9 0.75 8.5 12.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2076 PF09849.9 EWM27391.1 - 0.86 9.6 25.5 1.2 9.1 25.5 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF2786 PF10979.8 EWM27391.1 - 1.2 9.1 6.6 5.4 7.0 3.8 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2786) Mpp10 PF04006.12 EWM27391.1 - 1.6 7.1 25.6 2.1 6.7 25.6 1.1 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 EWM27391.1 - 2.2 6.4 40.0 2.9 6.0 40.0 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 EWM27391.1 - 4.9 5.1 47.8 7.4 4.5 47.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF913 PF06025.12 EWM27391.1 - 5.2 6.0 6.3 7.4 5.4 6.3 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Afi1 PF07792.12 EWM27391.1 - 5.2 7.6 17.7 12 6.4 17.7 1.6 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Presenilin PF01080.17 EWM27391.1 - 5.7 5.6 6.4 7.1 5.3 6.4 1.1 1 0 0 1 1 1 0 Presenilin Kelch_4 PF13418.6 EWM27393.1 - 0.00014 21.8 1.7 0.62 10.1 0.0 3.8 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.25 EWM27393.1 - 0.049 13.2 0.3 12 5.5 0.1 2.8 2 0 0 2 2 2 0 Kelch motif Glyco_transf_49 PF13896.6 EWM27394.1 - 4.7e-39 134.7 0.0 2.6e-31 109.2 0.0 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan DEDD_Tnp_IS110 PF01548.17 EWM27396.1 - 0.0044 16.9 0.1 0.0069 16.3 0.1 1.3 1 0 0 1 1 1 1 Transposase BNR PF02012.20 EWM27397.1 - 0.13 12.3 1.1 0.77 10.0 1.1 2.4 1 0 0 1 1 1 0 BNR/Asp-box repeat WD40 PF00400.32 EWM27397.1 - 1.9 9.5 6.1 22 6.1 6.1 2.8 1 1 0 1 1 1 0 WD domain, G-beta repeat HTH_39 PF14090.6 EWM27398.1 - 0.072 12.8 0.0 11 5.9 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain SoxG PF04268.12 EWM27398.1 - 0.11 12.6 0.0 3.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Sarcosine oxidase, gamma subunit family SfsA_N PF17746.1 EWM27399.1 - 0.032 14.4 0.0 0.061 13.5 0.0 1.4 1 0 0 1 1 1 0 SfsA N-terminal OB domain WD40 PF00400.32 EWM27399.1 - 0.057 14.3 0.2 0.2 12.6 0.2 2.0 1 0 0 1 1 1 0 WD domain, G-beta repeat adh_short_C2 PF13561.6 EWM27400.1 - 4.3e-46 157.4 1.4 5.3e-46 157.1 1.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EWM27400.1 - 9.3e-40 136.2 0.2 1.2e-39 135.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EWM27400.1 - 7.4e-07 29.3 0.0 1.3e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_7 PF13241.6 EWM27400.1 - 0.012 16.0 0.1 0.04 14.4 0.1 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding RVT_1 PF00078.27 EWM27401.1 - 3.1e-08 33.4 0.0 4.3e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 EWM27401.1 - 0.0011 19.0 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Ank_2 PF12796.7 EWM27403.1 - 1.4e-22 80.1 0.0 2.1e-10 41.0 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EWM27403.1 - 1.3e-21 76.6 0.1 3.3e-08 33.9 0.0 4.5 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EWM27403.1 - 3.3e-19 68.7 0.1 9.1e-06 25.9 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EWM27403.1 - 4.1e-19 68.1 0.3 0.00023 21.5 0.1 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 EWM27403.1 - 1.1e-16 59.2 0.4 0.00048 20.4 0.1 5.4 5 0 0 5 5 5 4 Ankyrin repeat Pkinase PF00069.25 EWM27404.1 - 9.7e-07 28.4 0.0 7.9e-05 22.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain DUF4412 PF14371.6 EWM27404.1 - 0.018 14.8 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4412) Pkinase_fungal PF17667.1 EWM27404.1 - 0.037 12.8 0.0 0.051 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EWM27404.1 - 0.086 12.8 0.1 0.6 10.0 0.0 2.2 2 1 0 3 3 3 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EWM27404.1 - 0.25 10.6 0.0 0.36 10.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like HopJ PF08888.11 EWM27405.1 - 3.4e-33 114.1 0.0 5.3e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 HopJ type III effector protein Voltage_CLC PF00654.20 EWM27406.1 - 2.8e-76 257.1 24.8 2.8e-76 257.1 24.8 1.7 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EWM27406.1 - 0.00046 20.6 0.3 0.037 14.5 0.0 2.7 2 0 0 2 2 2 1 CBS domain TAT_signal PF10518.9 EWM27406.1 - 0.24 11.3 3.2 1.3 9.0 3.2 2.3 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence AAA PF00004.29 EWM27407.1 - 5.1e-18 65.8 0.0 8.1e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EWM27407.1 - 0.00039 20.9 0.1 0.00091 19.6 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EWM27407.1 - 0.016 15.5 0.0 0.08 13.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EWM27407.1 - 0.064 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EWM27407.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 EWM27407.1 - 0.24 11.7 0.0 0.42 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain adh_short PF00106.25 EWM27409.1 - 2.2e-16 59.9 0.0 1.9e-06 27.5 0.0 3.9 4 0 0 4 4 4 3 short chain dehydrogenase adh_short_C2 PF13561.6 EWM27409.1 - 3.1e-05 23.6 0.0 0.0054 16.3 0.0 3.1 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EWM27409.1 - 0.018 14.5 0.0 4.3 6.7 0.0 2.3 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family KR PF08659.10 EWM27409.1 - 0.025 14.5 0.1 0.051 13.5 0.1 1.5 1 1 0 1 1 1 0 KR domain REV PF00424.18 EWM27409.1 - 0.14 12.2 0.8 0.4 10.7 0.8 1.7 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) THF_DHG_CYH_C PF02882.19 EWM27409.1 - 0.21 10.9 0.0 0.35 10.2 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain YTH PF04146.15 EWM27410.1 - 4.3e-41 140.6 0.0 4.3e-41 140.6 0.0 2.6 2 1 0 2 2 1 1 YT521-B-like domain Dev_Cell_Death PF10539.9 EWM27410.1 - 1.6e-17 63.5 0.0 3e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Development and cell death domain zf-CCCH PF00642.24 EWM27410.1 - 5.8e-10 38.8 24.0 6.4e-07 29.1 0.4 5.0 5 0 0 5 5 5 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EWM27410.1 - 1.1e-07 31.7 28.9 0.02 15.0 7.9 5.0 4 1 1 5 5 5 3 Zinc finger domain Torus PF16131.5 EWM27410.1 - 0.00012 22.8 3.4 0.015 16.0 0.0 4.7 5 0 0 5 5 4 3 Torus domain zf-CCCH_4 PF18044.1 EWM27410.1 - 0.0026 17.5 23.8 0.0088 15.8 0.8 4.2 4 0 0 4 4 4 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 EWM27410.1 - 0.0067 16.6 2.1 0.0067 16.6 2.1 3.5 4 0 0 4 4 4 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 EWM27410.1 - 0.38 11.3 30.7 0.06 13.9 1.3 4.2 4 0 0 4 4 4 0 RNA-binding, Nab2-type zinc finger Presenilin PF01080.17 EWM27410.1 - 2.1 7.0 7.6 3.4 6.3 7.6 1.2 1 0 0 1 1 1 0 Presenilin Hydin_ADK PF17213.3 EWM27410.1 - 2.8 8.2 9.3 5.2 7.3 9.3 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Neur_chan_memb PF02932.16 EWM27410.1 - 3.4 7.6 5.0 6.2 6.8 5.0 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Spt20 PF12090.8 EWM27410.1 - 4.1 7.0 30.4 0.49 10.0 3.9 2.3 2 0 0 2 2 2 0 Spt20 family PKI PF02827.16 EWM27410.1 - 9.7 6.5 7.5 20 5.5 0.7 3.0 2 0 0 2 2 2 0 cAMP-dependent protein kinase inhibitor Mad3_BUB1_I PF08311.12 EWM27411.1 - 4.5e-39 133.2 0.6 6.3e-39 132.8 0.6 1.2 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_I_2 PF17014.5 EWM27411.1 - 0.0012 18.9 0.0 0.0036 17.4 0.0 1.6 1 1 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein Ank_2 PF12796.7 EWM27412.1 - 4.8e-24 84.8 0.0 1.3e-08 35.3 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EWM27412.1 - 6.4e-22 77.3 0.1 3.5e-06 27.2 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EWM27412.1 - 1.3e-17 63.9 0.1 4.8e-08 33.4 0.0 3.2 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EWM27412.1 - 1.4e-16 60.1 0.0 2e-05 24.8 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 EWM27412.1 - 2.2e-16 58.3 0.1 0.00071 19.8 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat FeThRed_A PF02941.15 EWM27413.1 - 9.9e-08 32.0 0.0 1.6e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Ferredoxin thioredoxin reductase variable alpha chain Mito_carr PF00153.27 EWM27416.1 - 8.3e-41 137.8 6.2 3.2e-14 52.6 0.0 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF1992 PF09350.10 EWM27416.1 - 1.2e-13 51.0 0.0 6.4e-13 48.7 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) DUF3306 PF11748.8 EWM27416.1 - 0.15 12.9 2.5 0.16 12.8 1.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) BAF1_ABF1 PF04684.13 EWM27416.1 - 0.49 9.4 2.3 0.7 8.9 2.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor OAD_gamma PF04277.13 EWM27416.1 - 3.5 8.3 6.7 7.4 7.2 6.7 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain PFK PF00365.20 EWM27417.1 - 3e-60 204.0 0.0 5.1e-32 111.3 0.0 3.8 2 2 0 2 2 2 2 Phosphofructokinase TPP_enzyme_N PF02776.18 EWM27417.1 - 0.1 12.2 2.4 1.9 8.1 0.0 3.4 4 0 0 4 4 4 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Asp PF00026.23 EWM27418.1 - 1.2e-34 120.2 0.0 1.1e-21 77.7 0.0 2.7 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EWM27418.1 - 3.6e-10 40.4 0.0 7.6e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EWM27418.1 - 5.1e-05 23.1 0.0 8.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal PI3K_1B_p101 PF10486.9 EWM27418.1 - 0.26 9.0 0.2 0.37 8.5 0.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF4637 PF15470.6 EWM27418.1 - 6.1 6.5 8.6 13 5.5 8.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Exo_endo_phos PF03372.23 EWM27419.1 - 4.4e-08 32.9 0.0 1.2e-07 31.5 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Methyltransf_12 PF08242.12 EWM27420.1 - 0.00031 21.4 0.0 0.00064 20.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM27420.1 - 0.00042 21.0 0.0 0.00096 19.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EWM27420.1 - 0.0015 18.1 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DnaJ_CXXCXGXG PF00684.19 EWM27420.1 - 0.0027 18.0 4.8 0.14 12.5 0.3 2.7 2 0 0 2 2 2 2 DnaJ central domain Methyltransf_31 PF13847.6 EWM27420.1 - 0.011 15.5 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Anti-TRAP PF15777.5 EWM27420.1 - 0.068 13.1 1.2 2.3 8.2 0.1 2.6 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Methyltransf_4 PF02390.17 EWM27420.1 - 0.072 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_23 PF13489.6 EWM27420.1 - 0.16 11.8 0.0 0.34 10.7 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain MetW PF07021.12 EWM27420.1 - 0.22 11.1 0.3 0.56 9.8 0.1 1.7 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW GST_C_3 PF14497.6 EWM27422.1 - 3.2e-12 46.5 0.0 6.4e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EWM27422.1 - 3.2e-05 24.1 0.0 6.7e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EWM27422.1 - 0.001 19.1 0.1 0.0025 17.8 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF677 PF05055.12 EWM27422.1 - 0.13 11.1 0.0 1 8.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF677) Mo-co_dimer PF03404.16 EWM27423.1 - 3.5e-35 121.0 0.1 4.6e-35 120.6 0.1 1.1 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 EWM27423.1 - 3e-16 59.5 0.2 4.8e-16 58.8 0.2 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Big_7 PF17957.1 EWM27423.1 - 0.0039 17.9 0.0 0.0069 17.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial Ig domain BNR PF02012.20 EWM27423.1 - 0.017 15.0 0.0 0.092 12.8 0.0 2.4 1 0 0 1 1 1 0 BNR/Asp-box repeat PRR20 PF15708.5 EWM27424.1 - 0.028 14.4 0.9 0.042 13.8 0.9 1.2 1 0 0 1 1 1 0 Proline-rich protein family 20 Cyt-b5 PF00173.28 EWM27425.1 - 7e-10 38.9 0.0 1.1e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MEA1 PF06910.11 EWM27426.1 - 1.8e-06 28.6 2.4 2e-05 25.2 0.1 2.4 2 0 0 2 2 2 1 Male enhanced antigen 1 (MEA1) Ribosomal_60s PF00428.19 EWM27426.1 - 8.1 7.1 11.1 0.14 12.7 3.3 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein zf-Tim10_DDP PF02953.15 EWM27429.1 - 5.6e-16 57.9 2.4 1.1e-15 57.0 2.4 1.5 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Hormone_recep PF00104.30 EWM27429.1 - 0.0046 16.6 0.2 0.0062 16.1 0.2 1.1 1 0 0 1 1 1 1 Ligand-binding domain of nuclear hormone receptor GATase PF00117.28 EWM27434.1 - 1.3e-25 90.3 0.0 1.7e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EWM27434.1 - 0.049 13.4 0.0 0.067 12.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase C26 DFRP_C PF16543.5 EWM27436.1 - 3.7e-15 56.2 14.9 3.7e-15 56.2 14.9 3.9 1 1 3 4 4 4 1 DRG Family Regulatory Proteins, Tma46 PAS_7 PF12860.7 EWM27436.1 - 0.23 11.6 2.7 0.67 10.1 0.1 2.5 1 1 1 3 3 3 0 PAS fold Chorismate_bind PF00425.18 EWM27439.1 - 3.9e-85 285.5 0.0 5.5e-85 285.0 0.0 1.1 1 0 0 1 1 1 1 chorismate binding enzyme UCH PF00443.29 EWM27440.1 - 1e-55 189.0 0.0 1.3e-55 188.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EWM27440.1 - 1.3e-20 74.2 0.1 3.8e-10 39.9 0.0 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase MyTH4 PF00784.17 EWM27440.1 - 0.086 13.3 0.1 0.22 12.0 0.1 1.6 1 0 0 1 1 1 0 MyTH4 domain Ribosomal_L27A PF00828.19 EWM27441.1 - 1.2e-31 110.1 0.1 1.9e-31 109.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Cation_ATPase_C PF00689.21 EWM27443.1 - 0.015 15.0 0.2 0.018 14.7 0.2 1.1 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus Mannosyl_trans3 PF11051.8 EWM27444.1 - 0.011 15.1 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Glyco_transf_8 PF01501.20 EWM27444.1 - 0.013 15.1 0.1 0.43 10.1 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 8 PELOTA_1 PF15608.6 EWM27444.1 - 0.14 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 PELOTA RNA binding domain DcpS_C PF11969.8 EWM27445.1 - 1.3e-17 64.3 0.9 2.2e-17 63.5 0.9 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 EWM27445.1 - 5.6e-12 46.2 0.1 1.1e-11 45.3 0.1 1.5 1 0 0 1 1 1 1 HIT domain zf-C2HE PF16278.5 EWM27445.1 - 7.3e-11 42.4 0.1 1.6e-10 41.2 0.1 1.6 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger DUF1180 PF06679.12 EWM27448.1 - 0.25 11.8 0.6 0.43 11.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) ArsA_ATPase PF02374.15 EWM27451.1 - 6.5e-108 360.5 0.0 5.7e-95 318.0 0.0 2.0 1 1 1 2 2 2 2 Anion-transporting ATPase CbiA PF01656.23 EWM27451.1 - 1.2e-11 44.8 0.0 3e-11 43.5 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EWM27451.1 - 3.4e-11 43.4 0.0 1.4e-10 41.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 EWM27451.1 - 6.1e-06 25.9 0.2 3.4e-05 23.4 0.1 2.0 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 EWM27451.1 - 1.1e-05 25.0 0.2 0.00045 19.7 0.1 2.2 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 EWM27451.1 - 3.8e-05 23.3 0.0 9.9e-05 21.9 0.0 1.6 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ PhoH PF02562.16 EWM27451.1 - 0.00023 20.7 0.0 0.0005 19.6 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein SRP54 PF00448.22 EWM27451.1 - 0.0015 18.2 0.2 0.0061 16.2 0.1 1.9 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.6 EWM27451.1 - 0.015 14.9 0.0 0.22 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EWM27451.1 - 0.037 13.8 0.0 0.23 11.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain Thyroglob_assoc PF16597.5 EWM27451.1 - 0.043 14.1 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 Thyroglobulin_1 repeat associated disordered domain DUF2868 PF11067.8 EWM27451.1 - 0.047 13.2 0.0 0.071 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) NB-ARC PF00931.22 EWM27451.1 - 0.14 11.3 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain SNAP PF14938.6 EWM27452.1 - 2.1e-19 70.0 8.7 3e-19 69.5 8.7 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP Cuticle_3 PF11018.8 EWM27452.1 - 0.0023 18.2 2.3 0.0036 17.5 2.3 1.3 1 0 0 1 1 1 1 Pupal cuticle protein C1 TOM20_plant PF06552.12 EWM27452.1 - 0.0088 15.8 0.5 0.028 14.2 0.9 1.5 2 0 0 2 2 2 1 Plant specific mitochondrial import receptor subunit TOM20 DUF3463 PF11946.8 EWM27452.1 - 0.1 12.4 0.1 0.17 11.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3463) Peptidase_M20 PF01546.28 EWM27453.1 - 7.6e-28 97.6 0.0 1.1e-27 97.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EWM27453.1 - 1.6e-14 53.8 0.0 8.8e-14 51.3 0.0 2.2 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EWM27453.1 - 6.5e-05 22.7 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 TruB_N PF01509.18 EWM27454.1 - 0.069 13.5 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 TruB family pseudouridylate synthase (N terminal domain) Sel1 PF08238.12 EWM27454.1 - 0.09 13.5 0.3 1.1 10.1 0.1 2.8 2 0 0 2 2 2 0 Sel1 repeat Mito_fiss_reg PF05308.11 EWM27454.1 - 0.18 11.8 4.8 2.6 8.1 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial fission regulator DDE_Tnp_1_2 PF13586.6 EWM27454.1 - 0.34 11.3 1.6 0.73 10.2 0.0 2.4 3 0 0 3 3 3 0 Transposase DDE domain Hist_deacetyl PF00850.19 EWM27455.1 - 3.1e-52 178.0 0.0 5.4e-52 177.2 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain IBR PF01485.21 EWM27456.1 - 1.1e-13 51.2 48.1 2.7e-09 37.1 1.4 5.4 4 1 1 5 5 5 3 IBR domain, a half RING-finger domain RWD PF05773.22 EWM27456.1 - 2.3e-12 47.2 0.0 7.1e-12 45.6 0.0 1.8 1 1 0 1 1 1 1 RWD domain zf-C3HC4 PF00097.25 EWM27456.1 - 0.0024 17.7 2.4 0.0024 17.7 2.4 5.1 5 1 1 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EWM27456.1 - 0.012 15.7 4.7 0.012 15.7 4.7 4.1 4 0 0 4 4 4 0 RING-type zinc-finger Methyltransf_16 PF10294.9 EWM27458.1 - 2.4e-26 92.5 0.0 1.7e-25 89.8 0.0 2.3 2 1 0 2 2 2 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EWM27458.1 - 0.013 15.3 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 EWM27458.1 - 0.27 10.6 0.1 0.43 9.9 0.1 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G APH PF01636.23 EWM27460.1 - 4e-10 40.0 1.4 6e-10 39.4 1.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Aa_trans PF01490.18 EWM27461.1 - 1.1e-07 30.9 2.0 1.4e-07 30.6 2.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ABC2_membrane PF01061.24 EWM27462.1 - 6.3e-29 100.9 21.9 6.3e-29 100.9 21.9 2.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 EWM27462.1 - 4.5e-26 92.0 0.1 7.9e-26 91.2 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EWM27462.1 - 9.8e-05 22.3 0.4 0.03 14.1 0.2 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EWM27462.1 - 0.00014 21.5 0.4 0.00032 20.4 0.4 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EWM27462.1 - 0.0033 17.8 0.3 0.0084 16.5 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 EWM27462.1 - 0.0069 16.0 0.3 0.017 14.7 0.1 1.7 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 EWM27462.1 - 0.0072 15.8 0.5 0.2 11.0 0.5 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EWM27462.1 - 0.014 15.3 1.1 0.022 14.7 0.1 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 EWM27462.1 - 0.015 15.8 0.0 0.036 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EWM27462.1 - 0.016 15.1 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 EWM27462.1 - 0.025 14.5 0.0 0.058 13.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 EWM27462.1 - 0.027 14.7 0.0 0.066 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Laminin_EGF PF00053.24 EWM27462.1 - 0.076 13.2 5.0 0.34 11.1 5.0 2.1 1 0 0 1 1 1 0 Laminin EGF domain AAA_23 PF13476.6 EWM27462.1 - 0.083 13.4 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain EGF_2 PF07974.13 EWM27462.1 - 0.16 12.4 3.2 0.16 12.4 0.9 2.3 2 0 0 2 2 1 0 EGF-like domain Mito_carr PF00153.27 EWM27463.1 - 4.7e-57 189.9 2.5 1.3e-19 69.9 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Gp_dh_C PF02800.20 EWM27464.1 - 2.9e-69 231.7 0.0 3.9e-69 231.3 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EWM27464.1 - 1.1e-18 67.4 0.0 2.6e-18 66.2 0.0 1.7 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain REV PF00424.18 EWM27466.1 - 0.11 12.5 1.2 0.16 12.0 1.2 1.2 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) OrfB_IS605 PF01385.19 EWM27466.1 - 0.38 11.0 3.1 0.6 10.3 3.1 1.3 1 0 0 1 1 1 0 Probable transposase Biotin_lipoyl PF00364.22 EWM27468.1 - 0.16 11.8 0.0 1.1 9.2 0.0 2.2 1 1 0 2 2 2 0 Biotin-requiring enzyme ThiC_Rad_SAM PF01964.18 EWM27469.1 - 3.9e-194 645.2 0.0 4.7e-194 645.0 0.0 1.1 1 0 0 1 1 1 1 Radical SAM ThiC family ThiC-associated PF13667.6 EWM27469.1 - 2.6e-07 30.4 0.0 8.1e-07 28.8 0.0 1.9 1 0 0 1 1 1 1 ThiC-associated domain TAF PF02969.17 EWM27470.1 - 6.5e-12 45.4 0.1 1.1e-11 44.7 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 EWM27470.1 - 6.9e-06 26.4 0.1 1.1e-05 25.8 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 EWM27470.1 - 0.001 19.0 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CBFD_NFYB_HMF PF00808.23 EWM27470.1 - 0.0038 17.5 0.2 0.0063 16.8 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF4 PF05236.14 EWM27470.1 - 0.066 13.0 0.0 0.069 12.9 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family TFIID-31kDa PF02291.15 EWM27470.1 - 0.14 12.2 0.1 0.45 10.6 0.0 1.8 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit DOT1 PF08123.13 EWM27471.1 - 1.1e-10 41.4 0.0 3.7e-10 39.7 0.0 1.7 1 1 0 1 1 1 1 Histone methylation protein DOT1 FAE1_CUT1_RppA PF08392.12 EWM27472.1 - 1.5e-103 346.1 0.0 2.4e-87 292.9 0.1 2.1 2 0 0 2 2 2 2 FAE1/Type III polyketide synthase-like protein Chal_sti_synt_C PF02797.15 EWM27472.1 - 1.1e-11 44.9 0.0 2.2e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III_C PF08541.10 EWM27472.1 - 2e-11 43.9 0.0 2.3e-10 40.5 0.0 2.3 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 EWM27472.1 - 6.2e-05 22.8 0.0 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Chal_sti_synt_N PF00195.19 EWM27472.1 - 0.00037 20.0 0.1 0.00065 19.2 0.1 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain FHA PF00498.26 EWM27474.1 - 6.1e-15 55.3 0.0 1.1e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EWM27474.1 - 2.5e-05 24.5 0.0 6.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain TAF6_C PF07571.13 EWM27476.1 - 4.3e-13 49.4 0.0 7.4e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain DUF2264 PF10022.9 EWM27476.1 - 0.032 13.3 0.0 0.042 12.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2264) PP2C PF00481.21 EWM27477.1 - 2.8e-11 43.5 0.0 1.3e-10 41.4 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C ABC2_membrane PF01061.24 EWM27479.1 - 9.6e-35 119.9 21.2 1.5e-34 119.2 21.2 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EWM27479.1 - 2.6e-25 89.5 0.0 4.1e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 EWM27479.1 - 0.00016 21.4 0.5 0.00032 20.4 0.5 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EWM27479.1 - 0.00023 21.1 0.0 0.0039 17.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 EWM27479.1 - 0.00024 20.3 12.5 0.00024 20.3 12.5 1.6 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_23 PF13476.6 EWM27479.1 - 0.00061 20.4 0.1 0.001 19.6 0.1 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EWM27479.1 - 0.00065 19.6 0.1 0.0069 16.3 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 EWM27479.1 - 0.012 15.1 0.0 0.56 9.6 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 EWM27479.1 - 0.017 14.7 0.0 0.04 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 EWM27479.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Dynamin family AAA_28 PF13521.6 EWM27479.1 - 0.13 12.5 0.2 0.26 11.5 0.2 1.5 1 0 0 1 1 1 0 AAA domain ABC2_membrane_2 PF12679.7 EWM27479.1 - 0.84 8.9 6.1 1.8 7.8 6.1 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein RRM_1 PF00076.22 EWM27480.1 - 4.3e-21 74.5 0.0 6.7e-21 73.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zinc_ribbon_4 PF13717.6 EWM27480.1 - 3.3e-10 39.7 0.3 5.7e-10 39.0 0.3 1.4 1 0 0 1 1 1 1 zinc-ribbon domain RRM_5 PF13893.6 EWM27480.1 - 0.00014 21.4 0.0 0.00021 20.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zinc_ribbon_5 PF13719.6 EWM27480.1 - 0.022 14.5 1.5 0.058 13.2 1.5 1.8 1 1 0 1 1 1 0 zinc-ribbon domain RRM_7 PF16367.5 EWM27480.1 - 0.053 13.6 0.1 0.12 12.6 0.1 1.6 1 0 0 1 1 1 0 RNA recognition motif DUF1428 PF07237.11 EWM27480.1 - 0.055 13.7 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) Elf1 PF05129.13 EWM27480.1 - 0.058 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like RRM_occluded PF16842.5 EWM27480.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif Zn_ribbon_recom PF13408.6 EWM27480.1 - 0.13 12.8 1.0 18 5.9 0.1 2.4 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain efThoc1 PF11957.8 EWM27481.1 - 5.5e-37 127.6 0.0 6.6e-37 127.3 0.0 1.0 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor RabGAP-TBC PF00566.18 EWM27482.1 - 9.7e-11 41.7 0.0 2.7e-10 40.3 0.0 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Ribosomal_L28e PF01778.17 EWM27483.1 - 1.4e-36 125.7 0.4 1.4e-36 125.7 0.4 2.3 3 0 0 3 3 3 1 Ribosomal L28e protein family Mak16 PF04874.14 EWM27483.1 - 2.6e-26 92.1 36.5 2.6e-26 92.1 36.5 2.7 1 1 1 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 EWM27483.1 - 0.0056 16.1 17.6 0.0073 15.7 17.6 1.2 1 0 0 1 1 1 1 BUD22 DUF4820 PF16091.5 EWM27483.1 - 0.3 10.4 5.7 0.61 9.4 5.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) TFIIA PF03153.13 EWM27483.1 - 0.48 10.4 9.7 0.6 10.0 9.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Na_trans_assoc PF06512.13 EWM27483.1 - 3 8.1 15.4 4.6 7.5 15.4 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated Exonuc_VII_L PF02601.15 EWM27483.1 - 7.7 6.0 8.3 10 5.6 8.0 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit efThoc1 PF11957.8 EWM27484.1 - 2.1e-24 86.1 0.0 6.6e-24 84.4 0.0 1.8 1 1 1 2 2 2 1 THO complex subunit 1 transcription elongation factor Nitroreductase PF00881.24 EWM27486.1 - 7.9e-23 81.4 0.0 8.8e-22 77.9 0.0 2.2 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 EWM27486.1 - 0.00054 19.6 0.0 0.31 10.6 0.0 2.1 2 0 0 2 2 2 2 Putative TM nitroreductase Ldh_1_C PF02866.18 EWM27487.1 - 4.2e-48 163.4 0.1 8.4e-48 162.5 0.1 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EWM27487.1 - 1.1e-45 155.2 0.0 1.8e-45 154.5 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EWM27487.1 - 0.00052 19.1 0.0 0.00079 18.5 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 EWM27487.1 - 0.00064 20.2 0.1 0.0046 17.4 0.0 2.3 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 EWM27487.1 - 0.011 15.0 1.3 0.054 12.8 0.4 2.5 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Lipase_GDSL_2 PF13472.6 EWM27491.1 - 7.9e-23 81.8 0.0 1.3e-22 81.1 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EWM27491.1 - 3.7e-17 63.0 0.0 6e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SgrT PF15894.5 EWM27491.1 - 0.13 12.2 0.1 86 3.2 0.0 3.4 3 1 1 4 4 4 0 Inhibitor of glucose uptake transporter SgrT GMC_oxred_N PF00732.19 EWM27492.1 - 1.7e-78 264.0 0.0 2.6e-78 263.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EWM27492.1 - 2.2e-35 122.3 0.0 5.6e-35 121.0 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EWM27492.1 - 0.00011 22.4 0.5 0.00026 21.2 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EWM27492.1 - 0.00054 19.2 3.8 0.0086 15.2 0.0 2.6 3 0 0 3 3 3 2 FAD binding domain Lycopene_cycl PF05834.12 EWM27492.1 - 0.0028 16.8 0.0 0.0054 15.8 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EWM27492.1 - 0.0062 15.8 0.4 0.015 14.5 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EWM27492.1 - 0.0067 16.1 6.5 0.04 13.5 4.9 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase Med29 PF11568.8 EWM27492.1 - 0.059 13.6 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 Mediator complex subunit 29 Mito_carr PF00153.27 EWM27493.1 - 8.8e-65 214.7 0.7 2.1e-23 82.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1328 PF07043.13 EWM27493.1 - 5.6 7.3 8.0 26 5.1 2.8 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1328) Ammonium_transp PF00909.21 EWM27494.1 - 1.6e-114 382.8 34.0 1.9e-114 382.5 34.0 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family DUF456 PF04306.13 EWM27494.1 - 0.00029 21.1 13.5 0.00029 21.1 13.5 3.4 4 0 0 4 4 4 1 Protein of unknown function (DUF456) Gly-zipper_YMGG PF13441.6 EWM27494.1 - 0.42 10.4 9.0 1.7 8.4 9.0 2.1 1 0 0 1 1 1 0 YMGG-like Gly-zipper Rer1 PF03248.13 EWM27495.1 - 1e-65 220.6 10.9 1.3e-65 220.3 10.9 1.1 1 0 0 1 1 1 1 Rer1 family DUF2208 PF09973.9 EWM27495.1 - 0.036 13.7 0.2 0.036 13.7 0.2 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) Ccdc124 PF06244.12 EWM27496.1 - 2.9e-32 111.9 4.7 2.9e-32 111.9 4.7 2.7 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 EWM27496.1 - 0.005 17.2 1.1 0.005 17.2 1.1 2.9 4 0 0 4 4 4 1 HMG (high mobility group) box Noelin-1 PF12308.8 EWM27496.1 - 0.0077 16.2 2.4 0.014 15.4 2.4 1.4 1 0 0 1 1 1 1 Neurogenesis glycoprotein SOBP PF15279.6 EWM27496.1 - 1.4 9.4 4.6 1.7 9.2 4.6 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein CDRT4 PF15213.6 EWM27496.1 - 6.7 7.3 7.5 2.8 8.6 3.7 2.1 1 1 1 2 2 2 0 CMT1A duplicated region transcript 4 protein Thioredoxin PF00085.20 EWM27497.1 - 0.0061 16.5 0.0 0.027 14.5 0.0 1.9 1 1 1 2 2 2 1 Thioredoxin DUF5529 PF17669.1 EWM27498.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5529) AAA_25 PF13481.6 EWM27499.1 - 0.00034 20.3 0.4 0.002 17.8 0.3 1.9 2 0 0 2 2 2 1 AAA domain RecA PF00154.21 EWM27499.1 - 0.0017 17.9 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 EWM27499.1 - 0.012 14.9 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Rad51 DUF393 PF04134.12 EWM27501.1 - 1.1e-21 78.3 0.0 1.6e-21 77.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF393 Dynactin_p22 PF07426.11 EWM27502.1 - 1.8e-06 28.0 0.0 5.9e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 Dynactin subunit p22 ATP-synt_ab PF00006.25 EWM27503.1 - 2.7e-36 125.2 0.0 5.8e-36 124.1 0.0 1.5 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.6 EWM27503.1 - 0.00083 19.0 0.0 0.004 16.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EWM27503.1 - 0.0017 18.8 0.0 0.0083 16.7 0.0 2.0 2 0 0 2 2 2 1 ABC transporter ATPase PF06745.13 EWM27503.1 - 0.0054 16.1 0.0 0.0093 15.3 0.0 1.4 1 0 0 1 1 1 1 KaiC MMR_HSR1 PF01926.23 EWM27503.1 - 0.0087 16.1 0.0 0.089 12.9 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase MeaB PF03308.16 EWM27503.1 - 0.033 13.2 0.1 0.068 12.2 0.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 EWM27503.1 - 0.041 13.1 0.0 0.076 12.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain TsaE PF02367.17 EWM27503.1 - 0.045 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 EWM27503.1 - 0.074 13.3 0.0 0.21 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EWM27503.1 - 0.18 12.2 0.0 1.4 9.4 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EWM27503.1 - 0.2 11.4 0.0 0.77 9.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EWM27503.1 - 0.22 11.9 0.0 4.7 7.6 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 EWM27503.1 - 0.24 11.8 2.1 0.88 9.9 0.0 2.7 2 2 0 2 2 2 0 AAA ATPase domain Ribosomal_L15e PF00827.17 EWM27504.1 - 3.5e-88 294.4 7.9 4e-88 294.2 7.9 1.0 1 0 0 1 1 1 1 Ribosomal L15 UTP15_C PF09384.10 EWM27505.1 - 1.2e-40 138.5 0.0 1.7e-40 138.1 0.0 1.2 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 EWM27505.1 - 1.3e-17 63.8 6.8 0.00031 21.5 0.1 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM27505.1 - 7.5e-09 35.8 0.0 0.053 13.8 0.0 3.4 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain DUF3965 PF13112.6 EWM27505.1 - 0.12 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3965) AAA_26 PF13500.6 EWM27506.1 - 2.3e-18 66.7 0.0 4.3e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Hydrolase_4 PF12146.8 EWM27507.1 - 1.9e-12 47.0 0.0 3e-07 30.0 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EWM27507.1 - 3.7e-07 31.0 0.4 0.00017 22.3 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EWM27507.1 - 1.7e-06 27.9 0.0 0.0057 16.3 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EWM27507.1 - 6.1e-06 25.9 0.0 0.0001 21.9 0.0 2.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 EWM27507.1 - 0.015 14.8 0.0 0.16 11.5 0.0 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 EWM27507.1 - 0.036 13.9 0.0 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF818 PF05677.12 EWM27507.1 - 0.18 10.8 0.0 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) WD40 PF00400.32 EWM27509.1 - 1.9e-64 212.0 16.4 3.8e-08 33.9 0.0 8.7 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM27509.1 - 6.7e-25 87.2 0.5 8.7e-05 22.7 0.2 6.2 2 2 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 EWM27509.1 - 2.1e-09 37.8 0.0 3.7e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 EWM27509.1 - 1.6e-08 33.9 0.0 0.67 8.8 0.0 5.4 4 2 2 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EWM27509.1 - 3.4e-08 33.2 0.3 1.6 8.8 0.0 4.7 4 0 0 4 4 4 3 WD40-like Beta Propeller Repeat Nup160 PF11715.8 EWM27509.1 - 1.1e-05 24.4 2.4 0.15 10.7 0.2 4.0 2 2 2 4 4 4 2 Nucleoporin Nup120/160 eIF2A PF08662.11 EWM27509.1 - 1.3e-05 25.2 0.1 0.021 14.7 0.0 3.5 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 EWM27509.1 - 0.00018 20.9 0.2 3 7.1 0.0 4.1 2 2 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.9 EWM27509.1 - 0.021 14.5 2.3 35 4.2 0.1 3.7 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Frtz PF11768.8 EWM27509.1 - 0.067 11.5 0.0 3.4 5.9 0.0 2.3 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz nos_propeller PF18764.1 EWM27509.1 - 0.21 11.6 0.5 35 4.4 0.0 3.5 4 0 0 4 4 4 0 Nitrous oxide reductase propeller repeat TFIIIC_delta PF12657.7 EWM27509.1 - 0.21 11.5 1.7 33 4.3 0.4 3.4 2 1 0 2 2 2 0 Transcription factor IIIC subunit delta N-term WD40_like PF17005.5 EWM27509.1 - 0.22 10.8 0.0 17 4.6 0.0 2.9 3 0 0 3 3 3 0 WD40-like domain PALB2_WD40 PF16756.5 EWM27509.1 - 0.25 10.2 2.2 4.3 6.2 0.3 2.8 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Glyco_hydro_3 PF00933.21 EWM27510.1 - 1.6e-69 234.8 0.0 2.1e-69 234.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EWM27510.1 - 1e-29 104.0 0.0 1.8e-29 103.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Med26 PF08711.11 EWM27511.1 - 0.068 13.2 0.1 0.31 11.1 0.1 2.2 2 1 0 2 2 2 0 TFIIS helical bundle-like domain Lipase_3 PF01764.25 EWM27512.1 - 1.2e-18 67.4 0.0 2e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PE-PPE PF08237.11 EWM27512.1 - 0.062 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 PE-PPE domain FSH1 PF03959.13 EWM27512.1 - 0.086 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Mtc PF03820.17 EWM27515.1 - 8.7e-61 205.7 0.0 1.1e-60 205.4 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Hist_deacetyl PF00850.19 EWM27517.1 - 2.8e-56 191.2 0.0 4.1e-56 190.7 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Lactamase_B PF00753.27 EWM27517.1 - 0.068 13.2 0.0 0.31 11.0 0.0 2.0 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Hen1_L PF12623.7 EWM27517.1 - 0.16 11.0 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 RNA repair, ligase-Pnkp-associating, region of Hen1 Cupin_4 PF08007.12 EWM27518.1 - 4.6e-37 128.2 0.0 1.6e-30 106.7 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein Cupin_8 PF13621.6 EWM27518.1 - 3.4e-08 33.5 0.0 0.0058 16.4 0.0 2.3 1 1 1 2 2 2 2 Cupin-like domain Cupin_2 PF07883.11 EWM27518.1 - 0.0072 16.0 0.0 0.031 14.0 0.0 2.0 2 0 0 2 2 2 1 Cupin domain JmjC PF02373.22 EWM27518.1 - 0.11 12.9 0.0 0.46 10.9 0.0 2.0 1 1 0 1 1 1 0 JmjC domain, hydroxylase ARD PF03079.14 EWM27518.1 - 0.17 12.0 0.0 0.39 10.9 0.0 1.5 1 0 0 1 1 1 0 ARD/ARD' family DDE_5 PF13546.6 EWM27519.1 - 0.053 12.9 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease Presenilin PF01080.17 EWM27520.1 - 3.9e-116 388.1 0.0 1e-115 386.8 0.0 1.6 1 1 0 1 1 1 1 Presenilin Zip PF02535.22 EWM27521.1 - 9.4e-23 80.9 10.7 6e-14 52.0 5.7 3.1 2 1 0 2 2 2 2 ZIP Zinc transporter CPP1-like PF11833.8 EWM27521.1 - 0.7 9.5 9.2 0.031 13.9 1.4 2.5 2 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like SNF2_N PF00176.23 EWM27522.1 - 1.2e-47 162.4 0.0 1.7e-47 161.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EWM27522.1 - 7e-13 48.9 0.0 1.9e-12 47.5 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EWM27522.1 - 0.0037 17.3 0.0 0.0088 16.1 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3535 PF12054.8 EWM27522.1 - 0.0041 16.4 0.0 0.024 13.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) HEAT_EZ PF13513.6 EWM27522.1 - 0.011 16.2 0.1 7.9 7.1 0.0 3.7 2 0 0 2 2 2 0 HEAT-like repeat HEAT PF02985.22 EWM27522.1 - 0.015 15.5 0.1 0.45 10.9 0.0 3.2 2 0 0 2 2 2 0 HEAT repeat SWI2_SNF2 PF18766.1 EWM27522.1 - 0.16 11.6 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase Endonuclease_NS PF01223.23 EWM27523.1 - 2.9e-54 184.3 0.0 3.7e-54 183.9 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease CTU2 PF10288.9 EWM27524.1 - 0.78 10.0 5.4 0.25 11.6 0.2 2.9 3 0 0 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 AAA_13 PF13166.6 EWM27524.1 - 1 7.9 14.2 0.88 8.1 4.9 3.2 3 0 0 3 3 3 0 AAA domain TPD52 PF04201.15 EWM27524.1 - 1.6 8.3 17.9 0.42 10.2 0.7 3.6 3 1 0 3 3 3 0 Tumour protein D52 family PCI PF01399.27 EWM27525.1 - 3.5e-14 53.2 0.0 7.5e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 PCI domain eIF3_N PF09440.10 EWM27525.1 - 2e-10 41.2 2.5 4.1e-10 40.2 2.5 1.6 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain OTU PF02338.19 EWM27526.1 - 1.9e-14 54.3 0.0 1.1e-13 51.8 0.0 2.3 1 1 0 1 1 1 1 OTU-like cysteine protease Lipase_3 PF01764.25 EWM27527.1 - 6.8e-25 87.6 0.0 1.2e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) C2 PF00168.30 EWM27527.1 - 1.2e-11 44.8 0.0 2.1e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 C2 domain DUF2974 PF11187.8 EWM27527.1 - 0.045 13.3 0.0 2.8 7.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) BRCT PF00533.26 EWM27528.1 - 3.6e-06 27.3 0.0 0.038 14.4 0.0 2.4 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EWM27528.1 - 3.1e-05 24.3 0.0 0.00032 21.0 0.0 2.3 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 EWM27528.1 - 0.22 11.4 0.0 2.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain FAD_binding_2 PF00890.24 EWM27529.1 - 1.1e-78 265.2 2.7 1.9e-78 264.4 2.7 1.4 1 0 0 1 1 1 1 FAD binding domain ApbE PF02424.15 EWM27529.1 - 3.5e-46 157.8 0.0 1e-31 110.4 0.0 2.2 2 0 0 2 2 2 2 ApbE family NAD_binding_1 PF00175.21 EWM27529.1 - 3.1e-14 53.5 0.0 6.6e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_oxidored PF12831.7 EWM27529.1 - 3.9e-10 39.7 2.4 5.8e-10 39.1 1.3 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 EWM27529.1 - 8.3e-10 38.8 2.6 3.5e-09 36.7 1.1 2.8 2 2 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_6 PF00970.24 EWM27529.1 - 1.9e-09 37.8 0.0 3.9e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_8 PF13450.6 EWM27529.1 - 4.7e-08 33.2 2.4 2e-06 27.9 1.5 3.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EWM27529.1 - 2.1e-06 27.1 5.2 5.2e-05 22.5 2.5 3.0 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EWM27529.1 - 4.7e-06 26.1 0.1 8.3e-05 22.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EWM27529.1 - 6.1e-05 21.9 5.4 0.00041 19.2 2.8 2.4 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 EWM27529.1 - 0.0001 21.6 1.7 0.0002 20.7 1.7 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 EWM27529.1 - 0.0047 17.5 1.5 0.15 12.6 1.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EWM27529.1 - 0.013 14.8 1.1 0.022 14.0 1.1 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 EWM27529.1 - 0.017 14.3 1.7 0.027 13.7 0.5 1.9 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.6 EWM27529.1 - 0.035 13.4 0.8 0.1 11.8 0.1 2.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DXP_reductoisom PF02670.16 EWM27529.1 - 0.061 14.0 0.0 0.49 11.1 0.0 2.4 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Helicase_C PF00271.31 EWM27530.1 - 2.3e-28 98.8 0.1 4.2e-28 97.9 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1525 PF07511.11 EWM27530.1 - 0.73 10.0 3.5 3.2 7.9 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1525) Tau95 PF09734.9 EWM27531.1 - 9.1e-23 81.6 0.0 1.6e-22 80.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 EWM27531.1 - 1.3e-15 57.7 0.0 5.2e-15 55.8 0.0 2.0 1 1 0 1 1 1 1 Tau95 Triple barrel domain Sin_N PF04801.13 EWM27532.1 - 3.1e-70 237.5 0.0 5e-70 236.9 0.0 1.2 1 0 0 1 1 1 1 Sin-like protein conserved region HPIP PF15226.6 EWM27533.1 - 0.1 13.0 0.3 0.21 12.0 0.3 1.5 1 0 0 1 1 1 0 HCF-1 beta-propeller-interacting protein family Spc24 PF08286.11 EWM27534.1 - 5.9e-10 39.3 2.4 1.5e-09 38.1 0.1 2.1 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 Laminin_II PF06009.12 EWM27534.1 - 0.021 14.8 1.0 0.021 14.8 1.0 2.1 1 1 1 2 2 2 0 Laminin Domain II DUF1690 PF07956.11 EWM27534.1 - 1.7 9.1 6.6 2.3 8.6 2.7 2.9 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) ApoLp-III PF07464.11 EWM27534.1 - 2.2 8.3 8.5 6 7.0 2.6 2.2 1 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) ZapB PF06005.12 EWM27534.1 - 3.4 8.2 8.2 5.8e+02 1.0 8.2 2.6 1 1 0 1 1 1 0 Cell division protein ZapB Sipho_Gp157 PF05565.11 EWM27534.1 - 3.9 7.5 10.9 0.6 10.1 1.5 2.1 1 1 1 2 2 2 0 Siphovirus Gp157 DivIC PF04977.15 EWM27534.1 - 4 7.3 7.0 2.1 8.2 1.1 2.4 1 1 0 2 2 2 0 Septum formation initiator Aminotran_1_2 PF00155.21 EWM27535.1 - 2.1e-55 188.4 0.0 2.7e-55 188.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EWM27535.1 - 1.7e-06 26.8 0.0 3.6e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Methyltransf_25 PF13649.6 EWM27536.1 - 2.5e-11 44.1 0.0 1.2e-10 41.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EWM27536.1 - 8.4e-10 38.7 0.0 1.3e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM27536.1 - 6.3e-08 33.2 0.0 1.2e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EWM27536.1 - 4.5e-07 30.5 0.0 9.3e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EWM27536.1 - 3e-06 27.1 0.0 4.3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EWM27536.1 - 6.3e-06 26.1 0.0 1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EWM27536.1 - 0.00023 20.6 0.0 0.0003 20.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EWM27536.1 - 0.00037 20.1 0.0 0.00091 18.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EWM27536.1 - 0.00065 19.7 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EWM27536.1 - 0.0022 17.4 0.0 0.0075 15.6 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_PK PF05891.12 EWM27536.1 - 0.0093 15.5 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_2 PF00891.18 EWM27536.1 - 0.025 13.9 0.0 0.064 12.5 0.0 1.7 2 1 0 2 2 2 0 O-methyltransferase domain tRNA-synt_1d PF00750.19 EWM27537.1 - 9e-122 406.3 0.0 1.2e-121 405.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EWM27537.1 - 5.4e-31 107.2 0.1 1.4e-30 105.9 0.1 1.8 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 EWM27537.1 - 3e-23 82.2 0.0 7.6e-23 80.9 0.0 1.7 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.19 EWM27537.1 - 0.042 13.2 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain RRM_1 PF00076.22 EWM27539.1 - 3.1e-41 139.0 0.0 4.5e-22 77.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EWM27539.1 - 7.9e-08 32.3 0.0 0.0064 16.6 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 EWM27539.1 - 3.3e-06 26.9 0.0 0.083 12.8 0.0 2.8 2 1 0 2 2 2 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EWM27539.1 - 0.0095 15.9 0.0 3 7.9 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Cation_efflux PF01545.21 EWM27540.1 - 1.5e-38 132.5 28.5 4.5e-38 131.0 28.5 1.7 1 1 0 1 1 1 1 Cation efflux family BioT2 PF15368.6 EWM27540.1 - 0.059 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Spermatogenesis family BioT2 UPF0054 PF02130.17 EWM27540.1 - 0.3 10.9 0.1 0.3 10.9 0.1 2.8 2 0 0 2 2 2 0 Uncharacterized protein family UPF0054 DUF4834 PF16118.5 EWM27540.1 - 1.6 9.8 0.0 1.6 9.8 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) DUF1348 PF07080.11 EWM27541.1 - 4.6e-61 204.5 9.0 6e-61 204.1 9.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 EWM27541.1 - 4.5e-08 33.7 1.0 8.5e-08 32.8 1.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 EWM27541.1 - 0.0011 19.3 0.2 0.0018 18.6 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.12 EWM27541.1 - 0.1 12.4 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 EWM27542.1 - 0.00019 22.0 0.1 0.00041 20.9 0.1 1.6 1 0 0 1 1 1 1 SnoaL-like domain Ank_2 PF12796.7 EWM27543.1 - 6.8e-07 29.8 0.0 0.0019 18.7 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EWM27543.1 - 6.6e-06 26.3 1.6 0.16 12.4 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EWM27543.1 - 2.1e-05 25.0 0.1 0.0059 17.2 0.1 3.1 1 1 3 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EWM27543.1 - 0.0017 18.7 4.0 0.043 14.4 0.0 4.0 5 1 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 EWM27543.1 - 0.028 14.7 0.2 0.87 10.0 0.0 2.6 2 1 0 2 2 2 0 Ankyrin repeats (many copies) DnaJ PF00226.31 EWM27544.1 - 1.3e-18 66.9 1.2 2e-18 66.3 1.2 1.3 1 0 0 1 1 1 1 DnaJ domain tRNA_deacylase PF04414.12 EWM27547.1 - 5.2e-47 160.0 0.0 8.1e-47 159.4 0.0 1.3 1 0 0 1 1 1 1 D-aminoacyl-tRNA deacylase WD40 PF00400.32 EWM27547.1 - 4.2e-37 125.5 24.2 2.6e-05 24.9 1.2 11.2 10 0 0 10 10 10 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM27547.1 - 2.7e-07 30.8 4.9 1.2 9.5 0.1 6.5 6 1 0 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain DUF2798 PF11391.8 EWM27547.1 - 0.0033 17.4 0.5 0.0097 15.9 0.5 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2798) Ge1_WD40 PF16529.5 EWM27547.1 - 0.0081 15.1 0.2 13 4.6 0.0 3.9 4 0 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein IMS PF00817.20 EWM27548.1 - 3.6e-37 127.6 0.0 6.5e-37 126.8 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EWM27548.1 - 1e-16 61.7 0.0 2.7e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 EWM27548.1 - 8.3e-12 45.4 0.0 1.4e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EWM27548.1 - 3.7e-10 40.1 0.0 7.4e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.8 EWM27548.1 - 0.0017 18.5 0.0 0.006 16.8 0.0 2.0 1 0 0 1 1 1 1 IMS family HHH motif PTCB-BRCT PF12738.7 EWM27548.1 - 0.0062 16.5 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain REV1_C PF16727.5 EWM27548.1 - 0.028 14.8 0.2 0.11 12.9 0.2 2.1 1 0 0 1 1 1 0 DNA repair protein REV1 C-terminal domain UBM PF14377.6 EWM27548.1 - 0.054 13.0 13.8 0.061 12.8 0.5 3.4 3 0 0 3 3 3 0 Ubiquitin binding region Citrate_synt PF00285.21 EWM27549.1 - 4.2e-101 338.6 0.0 5.2e-101 338.3 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Acetyltransf_1 PF00583.25 EWM27550.1 - 2.4e-15 56.8 0.0 5.1e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EWM27550.1 - 1.6e-09 38.0 0.0 2.6e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EWM27550.1 - 2.6e-09 37.1 0.1 4.4e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EWM27550.1 - 3e-05 23.9 0.1 5.8e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 EWM27550.1 - 0.00022 20.9 0.0 0.00036 20.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EWM27550.1 - 0.011 15.8 0.1 0.027 14.6 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain UCH PF00443.29 EWM27551.1 - 2.1e-73 247.0 0.0 3.6e-73 246.2 0.0 1.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EWM27551.1 - 4.4e-19 68.9 0.0 9e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 EWM27551.1 - 1.6e-13 50.9 0.0 7.2e-05 22.5 0.0 3.3 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-ribbon_3 PF13248.6 EWM27551.1 - 0.35 10.3 2.0 3.5 7.2 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 EWM27551.1 - 1 9.4 4.7 1.4 8.9 0.6 2.4 2 0 0 2 2 2 0 zinc-ribbons EF-hand_6 PF13405.6 EWM27553.1 - 1.1e-09 37.5 0.1 0.00036 20.2 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EWM27553.1 - 1.6e-08 33.5 2.0 0.00011 21.5 0.3 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EWM27553.1 - 1.7e-06 28.4 1.5 0.037 14.5 0.1 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EWM27553.1 - 2.4e-06 26.8 2.7 0.00078 18.8 0.4 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EWM27553.1 - 0.0047 16.7 0.4 0.51 10.2 0.2 2.3 2 0 0 2 2 2 1 EF-hand domain pair LapA_dom PF06305.11 EWM27553.1 - 0.054 13.3 0.2 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain SPARC_Ca_bdg PF10591.9 EWM27553.1 - 0.71 10.2 3.2 6.5 7.1 3.2 2.3 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_6 PF13405.6 EWM27554.1 - 1.1e-09 37.4 0.2 0.00037 20.2 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EWM27554.1 - 1.6e-08 33.5 2.0 0.00011 21.5 0.3 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EWM27554.1 - 1.8e-06 28.3 1.6 0.037 14.5 0.1 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EWM27554.1 - 2.4e-06 26.8 2.7 0.00077 18.8 0.4 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EWM27554.1 - 0.0047 16.7 0.4 0.51 10.2 0.2 2.3 2 0 0 2 2 2 1 EF-hand domain pair LapA_dom PF06305.11 EWM27554.1 - 0.05 13.4 0.2 0.15 11.9 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain SPARC_Ca_bdg PF10591.9 EWM27554.1 - 0.75 10.1 3.4 7.1 7.0 3.4 2.3 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Macoilin PF09726.9 EWM27555.1 - 0.72 8.3 1.9 1 7.8 1.9 1.3 1 0 0 1 1 1 0 Macoilin family PHD PF00628.29 EWM27556.1 - 0.00037 20.3 10.1 0.00068 19.5 10.1 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.7 EWM27556.1 - 0.0056 17.2 0.7 0.013 16.1 0.7 1.6 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding Vps35 PF03635.17 EWM27556.1 - 0.13 10.8 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 35 Kinesin PF00225.23 EWM27557.1 - 5.6e-113 377.2 0.9 5.6e-113 377.2 0.9 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EWM27557.1 - 6e-26 91.2 0.4 6e-26 91.2 0.4 2.4 2 0 0 2 2 2 1 Microtubule binding PIF1 PF05970.14 EWM27557.1 - 0.0053 16.0 0.1 0.01 15.0 0.1 1.4 1 0 0 1 1 1 1 PIF1-like helicase Kinesin_assoc PF16183.5 EWM27557.1 - 0.013 15.6 13.8 0.22 11.7 11.8 2.8 2 1 0 2 2 2 0 Kinesin-associated Peptidase_S49_N PF08496.10 EWM27558.1 - 0.12 12.4 0.7 0.13 12.3 0.7 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1295 PF06966.12 EWM27559.1 - 1.4e-43 149.1 1.2 1.7e-43 148.8 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 EWM27559.1 - 0.00048 20.5 0.0 0.0019 18.6 0.0 1.9 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EWM27559.1 - 0.0013 19.1 3.6 0.0026 18.1 0.0 2.7 2 1 1 3 3 3 1 Phospholipid methyltransferase Steroid_dh PF02544.16 EWM27559.1 - 0.11 12.5 0.0 0.11 12.5 0.0 2.3 2 1 0 3 3 3 0 3-oxo-5-alpha-steroid 4-dehydrogenase E1-E2_ATPase PF00122.20 EWM27560.1 - 1.5e-25 89.8 0.0 2.2e-24 86.0 0.0 2.6 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EWM27560.1 - 1.5e-13 51.5 0.0 0.00022 21.6 0.0 3.4 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.8 EWM27560.1 - 0.0006 19.9 0.0 0.0013 18.9 0.0 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter Cation_ATPase PF13246.6 EWM27560.1 - 0.00065 19.7 0.0 0.0017 18.4 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Chorismate_synt PF01264.21 EWM27560.1 - 0.043 12.5 0.0 0.073 11.8 0.0 1.3 1 0 0 1 1 1 0 Chorismate synthase Cation_ATPase_N PF00690.26 EWM27560.1 - 0.082 12.6 2.1 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus ANF_receptor PF01094.28 EWM27561.1 - 2.8e-13 49.7 0.0 4.1e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region GTP_cyclohydro2 PF00925.20 EWM27561.1 - 0.013 15.2 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 GTP cyclohydrolase II S4 PF01479.25 EWM27562.1 - 0.0097 15.6 0.1 0.099 12.4 0.2 2.3 1 1 1 2 2 2 1 S4 domain TMEM214 PF10151.9 EWM27562.1 - 0.071 11.6 0.5 0.093 11.2 0.5 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator AATase PF07247.12 EWM27563.1 - 7.7e-06 24.7 0.1 0.00047 18.8 0.0 2.3 2 0 0 2 2 2 2 Alcohol acetyltransferase WES_acyltransf PF03007.16 EWM27563.1 - 0.00011 22.1 0.1 0.00066 19.5 0.0 2.1 2 0 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Condensation PF00668.20 EWM27563.1 - 0.00016 20.5 0.1 0.13 10.9 0.1 3.0 3 0 0 3 3 3 2 Condensation domain Radical_SAM PF04055.21 EWM27564.1 - 3.2e-09 37.4 0.0 7.2e-09 36.2 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.6 EWM27564.1 - 0.0019 18.3 0.0 0.0035 17.4 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 EWM27564.1 - 0.021 15.1 0.0 0.032 14.5 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S single cluster domain Peptidase_M41 PF01434.18 EWM27565.1 - 1.2e-62 211.2 0.6 2.1e-62 210.4 0.6 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EWM27565.1 - 3.4e-43 147.2 0.0 5.9e-43 146.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EWM27565.1 - 4e-10 39.3 0.0 1.1e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EWM27565.1 - 1.7e-05 24.9 0.0 4.2e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EWM27565.1 - 8.9e-05 22.3 0.0 0.0011 18.7 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EWM27565.1 - 0.00033 21.1 0.5 0.0048 17.3 0.5 2.3 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 EWM27565.1 - 0.00047 19.5 0.0 0.00083 18.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 EWM27565.1 - 0.0018 18.5 0.5 0.23 11.7 0.0 2.7 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 EWM27565.1 - 0.0072 16.1 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EWM27565.1 - 0.021 14.2 0.4 0.041 13.3 0.4 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EWM27565.1 - 0.043 14.4 0.0 0.13 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EWM27565.1 - 0.069 13.4 0.0 0.19 11.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_17 PF13207.6 EWM27565.1 - 0.08 13.4 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EWM27565.1 - 0.081 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Peptidase_M50B PF13398.6 EWM27565.1 - 0.089 12.4 0.1 0.089 12.4 0.1 1.9 2 0 0 2 2 2 0 Peptidase M50B-like AAA_2 PF07724.14 EWM27565.1 - 0.13 12.4 0.0 0.98 9.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) DUF1624 PF07786.12 EWM27565.1 - 0.21 11.1 0.1 0.35 10.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1624) Pkinase PF00069.25 EWM27566.1 - 4.5e-35 121.3 0.0 1.1e-34 120.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM27566.1 - 9.9e-32 110.2 0.0 2.2e-27 96.0 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EWM27566.1 - 0.00034 20.6 0.2 0.0019 18.2 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EWM27566.1 - 0.0019 17.1 0.0 0.0061 15.4 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 EWM27566.1 - 0.011 14.7 0.0 0.016 14.2 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 EWM27566.1 - 0.015 14.9 0.1 0.026 14.1 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.11 EWM27566.1 - 0.087 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Arm PF00514.23 EWM27567.1 - 5.6e-10 38.9 0.4 1.6e-06 28.0 0.0 3.5 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EWM27567.1 - 0.0035 17.7 2.0 0.0064 16.8 0.5 2.3 2 1 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.6 EWM27567.1 - 0.11 13.1 0.8 0.37 11.3 0.1 2.4 3 0 0 3 3 3 0 HEAT-like repeat DUF1515 PF07439.11 EWM27569.1 - 0.0011 18.9 2.6 0.011 15.7 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1515) DEAD_2 PF06733.15 EWM27570.1 - 3.1e-51 173.5 1.5 2.5e-50 170.5 0.8 2.2 2 0 0 2 2 2 1 DEAD_2 Helicase_C_2 PF13307.6 EWM27570.1 - 5.1e-43 147.2 0.0 2.2e-42 145.2 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain HBB PF06777.11 EWM27570.1 - 2.4e-30 105.6 0.1 7.4e-25 87.7 0.0 2.7 2 0 0 2 2 2 2 Helical and beta-bridge domain ResIII PF04851.15 EWM27570.1 - 2e-07 31.2 0.0 0.00022 21.3 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 EWM27570.1 - 0.00096 19.0 0.1 0.17 11.6 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase MIP PF00230.20 EWM27571.1 - 8.9e-30 104.1 23.9 7.8e-16 58.5 7.4 2.3 2 0 0 2 2 2 2 Major intrinsic protein HSP90 PF00183.18 EWM27572.1 - 3.8e-187 623.3 18.7 6.3e-187 622.6 18.7 1.3 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 EWM27572.1 - 1.6e-12 48.0 0.0 3.6e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EWM27572.1 - 8.8e-09 35.3 1.1 1.9e-08 34.3 0.2 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Prp18 PF02840.15 EWM27572.1 - 0.09 12.8 0.2 0.99 9.5 0.0 2.6 2 0 0 2 2 2 0 Prp18 domain Peptidase_C48 PF02902.19 EWM27573.1 - 1.3e-21 77.4 0.1 2.4e-09 37.4 0.0 3.4 3 0 0 3 3 3 3 Ulp1 protease family, C-terminal catalytic domain Myb_DNA-binding PF00249.31 EWM27574.1 - 0.0078 16.4 0.0 0.061 13.5 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain CTP_synth_N PF06418.14 EWM27575.1 - 2.7e-95 318.7 0.0 3.8e-95 318.2 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EWM27575.1 - 8.3e-51 172.5 0.0 1.2e-50 171.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EWM27575.1 - 1.1e-06 28.5 1.1 0.021 14.6 0.2 3.3 2 1 1 3 3 3 2 Peptidase C26 DJ-1_PfpI PF01965.24 EWM27575.1 - 0.017 14.9 0.1 0.035 13.9 0.1 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family AA_permease_2 PF13520.6 EWM27576.1 - 4.2e-28 98.3 37.8 5.1e-28 98.1 37.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EWM27576.1 - 1.1e-23 83.6 33.6 1.4e-23 83.2 33.6 1.0 1 0 0 1 1 1 1 Amino acid permease OB_NTP_bind PF07717.16 EWM27577.1 - 9.7e-16 57.9 0.0 1.9e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EWM27577.1 - 4.8e-15 55.8 0.0 1.1e-14 54.6 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EWM27577.1 - 1.8e-14 54.1 0.0 3.8e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EWM27577.1 - 1.2e-08 35.0 0.1 2.6e-08 33.9 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EWM27577.1 - 0.0003 21.1 0.1 0.00077 19.7 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EWM27577.1 - 0.00068 20.0 0.1 0.0015 18.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EWM27577.1 - 0.0036 16.7 0.0 0.0068 15.8 0.0 1.3 1 0 0 1 1 1 1 KaiC FtsK_SpoIIIE PF01580.18 EWM27577.1 - 0.025 13.9 0.0 0.059 12.7 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.6 EWM27577.1 - 0.035 13.8 0.2 0.084 12.6 0.2 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EWM27577.1 - 0.046 14.1 0.2 0.18 12.2 0.2 2.0 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EWM27577.1 - 0.054 14.0 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.26 EWM27577.1 - 0.07 12.8 0.1 0.82 9.4 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 EWM27577.1 - 0.084 12.4 0.0 0.27 10.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EWM27577.1 - 0.087 12.9 0.0 1.3 9.1 0.0 2.3 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 EWM27577.1 - 0.098 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein LETM1 PF07766.13 EWM27578.1 - 2.2e-98 328.9 0.4 2.2e-98 328.9 0.4 2.4 3 0 0 3 3 2 1 LETM1-like protein EF-hand_7 PF13499.6 EWM27578.1 - 6.8e-09 36.1 0.1 1.9e-08 34.6 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EWM27578.1 - 1e-06 27.8 0.0 0.071 12.7 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EWM27578.1 - 7.9e-06 25.4 0.1 0.045 13.7 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EWM27578.1 - 5.5e-05 22.9 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EWM27578.1 - 7.8e-05 22.0 0.1 0.24 10.9 0.0 2.5 2 0 0 2 2 2 2 EF hand Carn_acyltransf PF00755.20 EWM27578.1 - 0.017 13.8 0.4 0.032 12.9 0.4 1.4 1 0 0 1 1 1 0 Choline/Carnitine o-acyltransferase SPARC_Ca_bdg PF10591.9 EWM27578.1 - 0.064 13.6 0.3 0.064 13.6 0.3 2.5 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF4248 PF14053.6 EWM27578.1 - 0.12 12.4 0.1 0.65 10.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) SAP PF02037.27 EWM27578.1 - 0.22 11.3 0.0 0.22 11.3 0.0 2.8 3 0 0 3 3 3 0 SAP domain U79_P34 PF03064.16 EWM27578.1 - 0.24 10.7 7.5 0.43 9.9 7.5 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF1682 PF07946.14 EWM27578.1 - 1 8.5 16.1 3 7.0 16.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Eapp_C PF10238.9 EWM27578.1 - 1.1 9.3 4.6 2.5 8.2 4.6 1.6 1 0 0 1 1 1 0 E2F-associated phosphoprotein GAGA_bind PF06217.12 EWM27578.1 - 9.1 6.5 8.8 1.9 8.7 4.8 1.9 2 0 0 2 2 2 0 GAGA binding protein-like family Ribosomal_L25p PF01386.19 EWM27579.1 - 2e-15 57.1 0.0 4.2e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Ribosomal L25p family Ribosomal_TL5_C PF14693.6 EWM27579.1 - 6.1e-12 45.7 0.0 1.4e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein TL5, C-terminal domain ANAPC4 PF12896.7 EWM27580.1 - 2.1e-25 89.5 0.0 3.2e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 EWM27580.1 - 1.6e-17 63.6 0.0 3.3e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain DUF4506 PF14958.6 EWM27581.1 - 0.00015 21.3 0.0 0.00028 20.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4506) BLUF PF04940.12 EWM27581.1 - 0.18 12.0 0.1 0.33 11.1 0.1 1.4 1 0 0 1 1 1 0 Sensors of blue-light using FAD ERCC4 PF02732.15 EWM27582.1 - 0.042 14.1 0.1 0.047 13.9 0.1 1.1 1 0 0 1 1 1 0 ERCC4 domain FeS_assembly_P PF01883.19 EWM27583.1 - 8.7e-15 54.7 0.2 1.6e-14 53.8 0.0 1.5 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein B56 PF01603.20 EWM27585.1 - 1.1e-10 41.1 0.0 2e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DSPc PF00782.20 EWM27586.1 - 4e-23 81.7 0.1 5.8e-23 81.2 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EWM27586.1 - 0.00012 21.8 0.1 0.00032 20.3 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase CTP_transf_like PF01467.26 EWM27586.1 - 0.00056 20.1 0.0 0.0014 18.8 0.0 1.7 1 0 0 1 1 1 1 Cytidylyltransferase-like Y_phosphatase2 PF03162.13 EWM27586.1 - 0.031 13.9 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EWM27586.1 - 0.1 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family FAM75 PF14650.6 EWM27586.1 - 4.3 6.8 11.5 6.8 6.1 11.5 1.2 1 0 0 1 1 1 0 FAM75 family SBF PF01758.16 EWM27587.1 - 1.3e-36 126.2 16.7 2.5e-36 125.2 16.7 1.5 1 0 0 1 1 1 1 Sodium Bile acid symporter family SBF_like PF13593.6 EWM27587.1 - 5.3e-16 58.8 24.0 7.8e-16 58.3 24.0 1.3 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Adeno_E3 PF06040.11 EWM27587.1 - 5.3 7.2 5.6 16 5.6 1.2 2.5 1 1 1 2 2 2 0 Adenovirus E3 protein DHHC PF01529.20 EWM27588.1 - 1.1e-37 129.1 10.9 1.1e-37 129.1 10.9 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase UCR_UQCRX_QCR9 PF05365.12 EWM27589.1 - 2.6e-13 49.7 1.5 2.6e-13 49.7 1.5 1.5 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Lactamase_B_2 PF12706.7 EWM27590.1 - 2.8e-11 43.3 0.3 7.3e-11 41.9 0.3 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EWM27590.1 - 0.0062 16.6 0.5 0.019 15.0 0.2 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Terminase_4 PF05119.12 EWM27590.1 - 0.081 13.4 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 Phage terminase, small subunit Mito_carr PF00153.27 EWM27591.1 - 6.3e-69 228.0 2.5 7.3e-24 83.5 0.3 3.7 3 2 0 3 3 3 3 Mitochondrial carrier protein Mad3_BUB1_II PF08171.11 EWM27591.1 - 0.096 12.9 0.1 0.21 11.8 0.1 1.5 1 0 0 1 1 1 0 Mad3/BUB1 homology region 2 EF-hand_1 PF00036.32 EWM27592.1 - 8.4e-08 31.2 0.3 0.066 12.8 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EWM27592.1 - 6.2e-06 25.7 0.2 0.5 10.4 0.1 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 EWM27592.1 - 2.6e-05 24.6 0.3 0.0042 17.5 0.1 3.1 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 EWM27592.1 - 0.023 14.2 0.4 4.3 7.0 0.1 3.1 3 0 0 3 3 3 0 EF hand EF-hand_8 PF13833.6 EWM27592.1 - 0.028 14.3 0.4 14 5.7 0.0 2.9 2 1 0 2 2 2 0 EF-hand domain pair Acyltransferase PF01553.21 EWM27593.1 - 1.2e-14 54.1 0.0 2.1e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase XRN_M PF17846.1 EWM27594.1 - 1.4e-97 327.4 0.0 3.1e-97 326.3 0.0 1.5 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 EWM27594.1 - 2.3e-92 308.8 0.0 3.6e-92 308.2 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 EWM27594.1 - 1.1e-21 77.5 0.0 2.6e-12 46.9 0.0 2.4 1 1 1 2 2 2 2 Exoribonuclease Xrn1 D1 domain SH3_12 PF18129.1 EWM27594.1 - 2.6e-21 75.5 0.4 1.2e-20 73.4 0.0 2.2 2 0 0 2 2 2 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 EWM27594.1 - 0.016 15.3 0.0 0.044 13.9 0.0 1.8 1 0 0 1 1 1 0 Exoribonuclease 1 Domain-3 DUF1471 PF07338.13 EWM27594.1 - 0.13 12.2 0.2 0.33 11.0 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) NUDIX PF00293.28 EWM27595.1 - 1.3e-17 64.1 0.0 2.6e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain zf-RING_2 PF13639.6 EWM27596.1 - 2.9e-13 49.9 5.1 2.9e-13 49.9 5.1 3.2 3 1 0 3 3 3 1 Ring finger domain zf-RING_11 PF17123.5 EWM27596.1 - 5.2e-09 35.7 1.3 5.2e-09 35.7 1.3 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EWM27596.1 - 1.2e-08 34.7 3.8 1.2e-08 34.7 3.8 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EWM27596.1 - 7e-08 32.2 2.8 7e-08 32.2 2.8 2.8 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EWM27596.1 - 1.1e-07 32.0 3.4 1.1e-07 32.0 3.4 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EWM27596.1 - 5.6e-06 26.2 3.4 5.6e-06 26.2 3.4 3.5 4 0 0 4 4 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EWM27596.1 - 1.8e-05 24.5 5.2 1.8e-05 24.5 5.2 3.5 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EWM27596.1 - 9.4e-05 22.4 2.0 9.4e-05 22.4 2.0 3.6 4 0 0 4 4 4 1 RING-type zinc-finger zinc_ribbon_16 PF17034.5 EWM27596.1 - 0.12 12.6 5.0 0.44 10.8 1.3 2.5 2 0 0 2 2 2 0 Zinc-ribbon like family zf-ANAPC11 PF12861.7 EWM27596.1 - 0.12 12.4 5.8 0.083 13.0 1.7 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 EWM27596.1 - 0.79 9.9 9.8 0.095 12.8 4.3 2.4 2 1 0 2 2 2 0 RING-variant domain GST_N_3 PF13417.6 EWM27597.1 - 2.3e-12 47.1 0.0 1e-10 41.8 0.0 3.1 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EWM27597.1 - 3.9e-09 36.7 0.1 1.2e-08 35.1 0.1 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EWM27597.1 - 4.6e-06 26.6 0.1 1.4e-05 25.0 0.1 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 EWM27597.1 - 0.0012 19.0 0.0 0.0078 16.4 0.0 2.1 2 0 0 2 2 2 1 Glutaredoxin GST_C PF00043.25 EWM27597.1 - 0.025 14.8 0.0 0.055 13.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain 6PF2K PF01591.18 EWM27598.1 - 3.6e-53 180.2 0.0 5.3e-53 179.6 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EWM27598.1 - 2.6e-31 108.8 0.0 5.3e-31 107.8 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AMPK1_CBM PF16561.5 EWM27598.1 - 1.5e-22 79.6 0.1 2.8e-22 78.7 0.1 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AAA_33 PF13671.6 EWM27598.1 - 0.00013 22.1 0.3 0.00065 19.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 EWM27598.1 - 0.065 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 R3H PF01424.22 EWM27598.1 - 0.1 12.6 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 R3H domain IstB_IS21 PF01695.17 EWM27598.1 - 0.11 12.2 0.0 0.33 10.7 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_22 PF13401.6 EWM27598.1 - 0.14 12.4 0.0 0.38 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EWM27598.1 - 0.21 11.5 0.0 0.41 10.5 0.0 1.4 1 0 0 1 1 1 0 NTPase Ribosomal_L18 PF17135.4 EWM27599.1 - 4.8e-84 280.4 2.3 5.3e-84 280.3 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 EWM27599.1 - 0.0086 16.8 0.3 0.025 15.3 0.3 1.9 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A His_Phos_1 PF00300.22 EWM27600.1 - 5.7e-34 117.5 0.0 8.2e-28 97.4 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Exc PF07825.11 EWM27600.1 - 0.048 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Excisionase-like protein Abhydrolase_6 PF12697.7 EWM27601.1 - 6.9e-07 30.1 2.2 9.1e-07 29.7 2.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EWM27601.1 - 3.3e-06 26.9 0.9 6.3e-05 22.7 1.0 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EWM27601.1 - 4.8e-05 22.7 0.0 0.00011 21.5 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DNMT1-RFD PF12047.8 EWM27602.1 - 3.6e-06 27.1 0.0 7.9e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain SCAB_CC PF16712.5 EWM27602.1 - 0.065 13.1 6.8 0.14 12.0 6.8 1.5 1 0 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein TP53IP5 PF15331.6 EWM27602.1 - 2 8.5 10.1 4 7.5 9.2 1.9 2 0 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 MFAP1 PF06991.11 EWM27603.1 - 1.1e-60 205.3 23.7 1.1e-60 205.3 23.7 2.1 1 1 1 2 2 2 1 Microfibril-associated/Pre-mRNA processing UPF0240 PF06784.11 EWM27603.1 - 0.09 12.8 4.5 0.076 13.1 2.7 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0240) Cupin_6 PF12852.7 EWM27604.1 - 0.007 16.1 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Cupin Pho88 PF10032.9 EWM27606.1 - 4e-09 36.0 0.1 1.6e-08 34.0 0.1 1.8 1 1 0 1 1 1 1 Phosphate transport (Pho88) YadA_anchor PF03895.15 EWM27606.1 - 0.0085 16.2 0.0 0.024 14.7 0.0 1.8 1 0 0 1 1 1 1 YadA-like membrane anchor domain Glyco_hydro_1 PF00232.18 EWM27607.1 - 5.1e-164 546.0 0.2 6.6e-164 545.6 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 DNA_pol_B_exo2 PF10108.9 EWM27607.1 - 0.057 13.1 0.9 0.11 12.1 0.9 1.4 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Photo_RC PF00124.19 EWM27607.1 - 0.096 11.9 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Photosynthetic reaction centre protein AA_permease_2 PF13520.6 EWM27608.1 - 2.8e-56 191.2 34.7 3.6e-56 190.8 34.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EWM27608.1 - 2.1e-46 158.5 32.8 2.8e-46 158.1 32.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 EWM27608.1 - 5.8e-06 26.3 5.2 5.8e-06 26.3 5.2 3.2 4 0 0 4 4 4 1 C-terminus of AA_permease DUF4131 PF13567.6 EWM27608.1 - 1.4 8.6 12.0 1.6 8.3 0.3 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) UCH PF00443.29 EWM27609.1 - 1.2e-44 152.8 0.0 2.1e-44 152.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EWM27609.1 - 3e-21 76.4 0.0 5.5e-20 72.2 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Nop14 PF04147.12 EWM27609.1 - 5.7 5.0 7.9 14 3.7 7.9 1.6 1 0 0 1 1 1 0 Nop14-like family UCR_Fe-S_N PF10399.9 EWM27610.1 - 0.0011 18.3 0.6 0.0024 17.2 0.1 1.8 2 0 0 2 2 2 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal PsbQ PF05757.11 EWM27610.1 - 0.02 14.6 0.8 0.037 13.8 0.8 1.4 1 1 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) DUF1216 PF06746.11 EWM27610.1 - 0.12 12.4 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) BORCS7 PF16088.5 EWM27611.1 - 0.022 15.0 0.5 0.037 14.3 0.5 1.3 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 7 RepB_primase PF16793.5 EWM27611.1 - 0.058 13.5 0.0 0.072 13.2 0.0 1.3 1 0 0 1 1 1 0 RepB DNA-primase from phage plasmid Ran-binding PF05508.11 EWM27611.1 - 0.13 11.3 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 RanGTP-binding protein DUF3667 PF12412.8 EWM27612.1 - 0.0096 15.4 0.2 0.02 14.4 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3667) UBA_4 PF14555.6 EWM27613.1 - 2.4e-07 30.4 0.2 4.2e-07 29.7 0.2 1.3 1 0 0 1 1 1 1 UBA-like domain DUF3418 PF11898.8 EWM27613.1 - 0.023 13.4 0.2 0.03 13.0 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) Kinase-PolyVal PF18762.1 EWM27613.1 - 0.06 13.3 0.0 0.094 12.7 0.0 1.2 1 0 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins PPR_3 PF13812.6 EWM27614.1 - 0.049 13.7 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 Pentatricopeptide repeat domain Rad51 PF08423.11 EWM27615.1 - 8e-120 398.8 0.1 1.1e-119 398.4 0.1 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 EWM27615.1 - 3.4e-15 56.2 0.1 5.6e-15 55.5 0.1 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 EWM27615.1 - 8.9e-10 38.5 0.1 1.5e-09 37.8 0.1 1.3 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EWM27615.1 - 1.9e-09 37.2 0.4 4.1e-09 36.1 0.1 1.7 2 1 0 2 2 2 1 KaiC HHH_5 PF14520.6 EWM27615.1 - 3.3e-08 34.0 0.1 2e-07 31.5 0.0 2.3 3 0 0 3 3 3 1 Helix-hairpin-helix domain AAA_24 PF13479.6 EWM27615.1 - 0.0027 17.5 0.0 0.0083 15.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.15 EWM27615.1 - 0.0032 16.9 2.6 0.19 11.0 0.1 2.9 2 1 0 3 3 3 1 DnaB-like helicase C terminal domain HhH-GPD PF00730.25 EWM27615.1 - 0.0041 17.5 0.0 0.0073 16.8 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH_2 PF12826.7 EWM27615.1 - 0.031 14.4 0.0 0.091 12.9 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif PAXNEB PF05625.11 EWM27615.1 - 0.043 13.0 0.3 0.088 11.9 0.3 1.4 1 0 0 1 1 1 0 PAXNEB protein AAA_22 PF13401.6 EWM27615.1 - 0.046 14.0 0.1 0.12 12.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain OppC_N PF12911.7 EWM27616.1 - 0.44 10.6 2.1 25 4.9 0.0 2.2 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Methyltransf_11 PF08241.12 EWM27618.1 - 3.7e-20 72.4 0.0 1.2e-19 70.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM27618.1 - 9.6e-16 58.3 0.0 4.4e-15 56.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EWM27618.1 - 3.3e-12 46.5 0.0 1.1e-11 44.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM27618.1 - 1.5e-11 44.3 0.0 2.6e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EWM27618.1 - 1e-10 41.4 0.0 1.8e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 EWM27618.1 - 1.8e-09 37.3 0.0 3.2e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EWM27618.1 - 8.6e-07 29.6 0.0 3e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Sterol_MT_C PF08498.10 EWM27618.1 - 0.00028 21.2 0.1 0.0019 18.4 0.1 2.3 2 0 0 2 2 2 1 Sterol methyltransferase C-terminal DUF498 PF04430.14 EWM27619.1 - 5.7e-31 106.8 0.0 1e-29 102.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF498/DUF598) Aa_trans PF01490.18 EWM27620.1 - 6.6e-60 202.9 20.8 8.1e-60 202.6 20.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ldh_2 PF02615.14 EWM27621.1 - 3.5e-78 263.1 3.7 1.7e-77 260.9 3.7 1.8 1 1 0 1 1 1 1 Malate/L-lactate dehydrogenase Acetyltransf_1 PF00583.25 EWM27621.1 - 0.071 13.3 0.0 4 7.7 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 EWM27621.1 - 0.12 12.5 0.5 0.75 10.0 0.1 2.3 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase CDC45 PF02724.14 EWM27622.1 - 0.49 8.6 3.4 0.53 8.5 0.1 2.0 2 0 0 2 2 2 0 CDC45-like protein SMC_N PF02463.19 EWM27623.1 - 1.1e-07 31.5 0.0 2e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EWM27623.1 - 1.3e-05 25.3 0.0 3.8e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 EWM27623.1 - 0.00024 21.7 0.0 0.00024 21.7 0.0 3.2 3 1 0 3 3 3 1 AAA domain ABC_tran PF00005.27 EWM27623.1 - 0.026 15.1 0.5 0.25 11.8 0.5 2.8 1 1 0 1 1 1 0 ABC transporter ALS2CR11 PF15729.5 EWM27623.1 - 0.47 9.5 2.0 0.83 8.7 2.0 1.3 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 candidate 11 Apt1 PF10351.9 EWM27623.1 - 9.8 4.9 9.8 84 1.8 9.3 2.4 2 1 0 2 2 2 0 Golgi-body localisation protein domain Pyrid_oxidase_2 PF13883.6 EWM27625.1 - 1.5e-39 135.7 0.0 1.8e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase SDA1 PF05285.12 EWM27626.1 - 0.0039 16.7 18.2 0.0062 16.0 18.2 1.3 1 0 0 1 1 1 1 SDA1 SAPS PF04499.15 EWM27626.1 - 0.017 14.0 2.1 0.023 13.5 2.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DNA_pol_phi PF04931.13 EWM27626.1 - 0.026 12.6 25.6 0.033 12.3 25.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Zip PF02535.22 EWM27626.1 - 0.068 12.4 0.4 0.063 12.5 0.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Mpp10 PF04006.12 EWM27626.1 - 0.12 10.8 21.5 0.15 10.4 21.5 1.1 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 EWM27626.1 - 0.13 10.5 22.7 0.16 10.1 22.7 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 EWM27626.1 - 0.25 10.7 17.0 0.36 10.1 17.0 1.2 1 0 0 1 1 1 0 BUD22 Tim54 PF11711.8 EWM27626.1 - 0.25 10.1 10.1 0.4 9.4 10.1 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Sporozoite_P67 PF05642.11 EWM27626.1 - 0.32 9.0 3.4 0.5 8.4 3.4 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PI3K_1B_p101 PF10486.9 EWM27626.1 - 0.45 8.2 6.2 0.57 7.9 6.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SpoIIP PF07454.11 EWM27626.1 - 0.52 9.7 8.9 0.67 9.4 8.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Eapp_C PF10238.9 EWM27626.1 - 0.6 10.2 4.1 0.96 9.5 4.1 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein MRNIP PF15749.5 EWM27626.1 - 0.88 10.3 7.0 1.6 9.5 7.0 1.3 1 0 0 1 1 1 0 MRN-interacting protein Connexin PF00029.19 EWM27626.1 - 1.9 8.2 9.0 2.8 7.6 9.0 1.2 1 0 0 1 1 1 0 Connexin CDC45 PF02724.14 EWM27626.1 - 2.2 6.5 18.6 2.9 6.1 18.6 1.1 1 0 0 1 1 1 0 CDC45-like protein TEX19 PF15553.6 EWM27626.1 - 2.3 8.1 8.8 5 7.1 8.8 1.6 1 0 0 1 1 1 0 Testis-expressed protein 19 DDRGK PF09756.9 EWM27626.1 - 2.3 7.7 24.3 4.1 6.9 24.3 1.3 1 0 0 1 1 1 0 DDRGK domain DUF3408 PF11888.8 EWM27626.1 - 2.5 8.2 16.2 4.4 7.4 16.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Presenilin PF01080.17 EWM27626.1 - 2.6 6.7 7.8 3.6 6.3 7.8 1.1 1 0 0 1 1 1 0 Presenilin DUF3391 PF11871.8 EWM27626.1 - 2.7 8.5 9.8 4.5 7.8 9.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) NPR3 PF03666.13 EWM27626.1 - 3.5 6.3 6.8 4.5 5.9 6.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CPSF100_C PF13299.6 EWM27626.1 - 5 7.3 10.5 9.3 6.4 10.5 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal XRN_M PF17846.1 EWM27626.1 - 7.1 5.5 7.8 11 4.8 7.8 1.2 1 0 0 1 1 1 0 Xrn1 helical domain XAP5 PF04921.14 EWM27626.1 - 7.4 6.3 12.3 13 5.5 12.3 1.4 1 0 0 1 1 1 0 XAP5, circadian clock regulator AIF_C PF14721.6 EWM27626.1 - 7.4 6.9 7.1 12 6.2 7.1 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Vfa1 PF08432.10 EWM27626.1 - 7.8 6.8 12.8 12 6.1 12.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 MDM1 PF15501.6 EWM27626.1 - 9.7 5.2 15.3 16 4.4 15.3 1.3 1 0 0 1 1 1 0 Nuclear protein MDM1 Aa_trans PF01490.18 EWM27627.1 - 3.8e-61 207.0 7.2 5.3e-61 206.5 7.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Helicase_C PF00271.31 EWM27628.1 - 1e-15 58.1 0.0 4.2e-15 56.0 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 EWM27628.1 - 2.7e-15 56.6 0.0 1e-14 54.7 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EWM27628.1 - 1.8e-13 50.7 0.0 4.2e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EWM27628.1 - 1.2e-08 35.0 0.0 2.6e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 EWM27628.1 - 0.00088 19.6 0.0 0.0032 17.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EWM27628.1 - 0.0014 18.9 0.1 0.0048 17.2 0.1 1.9 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EWM27628.1 - 0.0086 15.2 0.0 0.028 13.5 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 EWM27628.1 - 0.013 15.1 0.1 0.031 13.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EWM27628.1 - 0.09 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Endosulfine PF04667.17 EWM27630.1 - 0.0032 17.5 0.4 0.087 13.0 0.1 2.7 2 0 0 2 2 2 1 cAMP-regulated phosphoprotein/endosulfine conserved region Spc7 PF08317.11 EWM27631.1 - 6e-05 22.1 11.0 0.00011 21.2 10.7 1.5 1 1 0 1 1 1 1 Spc7 kinetochore protein BLOC1_2 PF10046.9 EWM27631.1 - 0.00019 21.7 1.9 0.025 14.8 0.1 3.0 2 2 1 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6_N PF17675.1 EWM27631.1 - 0.00076 20.0 0.9 0.00076 20.0 0.9 2.5 2 1 0 2 2 2 1 Apg6 coiled-coil region Yuri_gagarin PF15934.5 EWM27631.1 - 0.19 11.5 10.9 0.48 10.2 6.3 2.2 2 0 0 2 2 2 0 Yuri gagarin GAS PF13851.6 EWM27631.1 - 0.45 9.9 14.2 1.9 7.8 3.9 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Snapin_Pallidin PF14712.6 EWM27631.1 - 1.1 9.7 4.1 6.3 7.3 0.3 2.9 2 1 0 3 3 3 0 Snapin/Pallidin Spectrin PF00435.21 EWM27631.1 - 1.2 9.7 10.6 0.42 11.1 0.6 2.9 2 1 1 3 3 3 0 Spectrin repeat Cep57_CLD_2 PF14197.6 EWM27631.1 - 8.8 6.5 15.5 0.41 10.8 2.2 3.0 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Abhydrolase_6 PF12697.7 EWM27632.1 - 3.1e-17 63.9 2.0 4.1e-17 63.5 2.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EWM27632.1 - 4.6e-05 22.8 0.0 8.4e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 AAA_lid_2 PF17863.1 EWM27632.1 - 0.1 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA lid domain Esterase PF00756.20 EWM27632.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Cupin_2 PF07883.11 EWM27633.1 - 0.00019 21.1 0.8 0.00049 19.8 0.7 1.7 1 1 1 2 2 2 1 Cupin domain Cupin_7 PF12973.7 EWM27633.1 - 0.0076 16.1 0.1 0.012 15.5 0.1 1.4 1 0 0 1 1 1 1 ChrR Cupin-like domain Ectoine_synth PF06339.12 EWM27633.1 - 0.035 14.3 0.1 0.061 13.5 0.1 1.4 1 0 0 1 1 1 0 Ectoine synthase DUF4437 PF14499.6 EWM27633.1 - 0.075 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) OKR_DC_1 PF01276.20 EWM27635.1 - 1.8e-43 148.8 0.0 7.8e-43 146.7 0.0 1.9 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain OKR_DC_1_C PF03711.15 EWM27635.1 - 1.9e-07 31.5 0.0 3.5e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, C-terminal domain SepSecS PF05889.13 EWM27635.1 - 3.5e-05 22.7 0.0 5.5e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Aminotran_1_2 PF00155.21 EWM27635.1 - 0.0024 17.1 0.0 0.0062 15.8 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EWM27635.1 - 0.075 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family NOG1_N PF17835.1 EWM27636.1 - 1.4e-18 67.3 1.6 2e-18 66.8 1.6 1.2 1 0 0 1 1 1 1 NOG1 N-terminal helical domain MMR_HSR1 PF01926.23 EWM27636.1 - 8e-17 61.4 0.0 2.8e-16 59.6 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase NOG1 PF06858.14 EWM27636.1 - 3.7e-16 58.6 0.0 7.6e-16 57.6 0.0 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) FeoB_N PF02421.18 EWM27636.1 - 2e-08 33.9 0.3 4.6e-08 32.7 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 EWM27636.1 - 0.0051 16.2 0.1 0.022 14.1 0.0 2.0 2 0 0 2 2 2 1 AIG1 family RsgA_GTPase PF03193.16 EWM27636.1 - 0.033 14.1 0.2 0.25 11.3 0.0 2.4 3 1 0 3 3 3 0 RsgA GTPase TniB PF05621.11 EWM27636.1 - 0.065 12.6 0.0 0.23 10.9 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein CPT PF07931.12 EWM27636.1 - 0.13 12.0 0.0 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Roc PF08477.13 EWM27636.1 - 0.16 12.2 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 EWM27636.1 - 0.16 11.6 0.1 0.33 10.6 0.0 1.4 2 0 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.23 EWM27636.1 - 0.17 12.0 0.3 25 4.9 0.0 2.5 1 1 1 2 2 2 0 Dynamin family Ribosomal_S26e PF01283.19 EWM27637.1 - 6.5e-41 139.1 7.2 6.5e-41 139.1 7.2 1.5 2 0 0 2 2 2 1 Ribosomal protein S26e FCH PF00611.23 EWM27639.1 - 1.4e-07 31.7 0.2 1e-06 28.9 0.1 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Ras PF00071.22 EWM27640.1 - 1.6e-64 216.4 0.1 2e-64 216.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EWM27640.1 - 2.6e-34 118.0 0.0 4.6e-34 117.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EWM27640.1 - 1.7e-16 60.2 0.1 2.1e-16 59.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EWM27640.1 - 1.4e-05 24.6 0.1 2e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EWM27640.1 - 3.1e-05 23.6 0.1 7e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EWM27640.1 - 0.004 17.1 0.0 2.1 8.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EWM27640.1 - 0.004 16.6 0.0 0.0056 16.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EWM27640.1 - 0.0057 16.7 0.0 0.0097 16.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 EWM27640.1 - 0.14 11.6 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region MmcB-like PF06319.12 EWM27640.1 - 0.17 11.5 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 DNA repair protein MmcB-like AAA_29 PF13555.6 EWM27640.1 - 0.18 11.6 0.0 0.68 9.7 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain Topoisom_I PF01028.20 EWM27641.1 - 1e-85 286.7 0.0 1e-85 286.7 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 EWM27641.1 - 4.9e-80 268.0 1.9 5.3e-80 267.9 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 EWM27641.1 - 1.1e-34 118.1 0.2 3.2e-34 116.7 0.2 1.8 1 0 0 1 1 1 1 C-terminal topoisomerase domain Med9 PF07544.13 EWM27641.1 - 2.2 8.4 9.8 12 6.1 0.7 2.8 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DHR10 PF18595.1 EWM27641.1 - 8.9 6.4 22.5 1.7 8.7 6.3 2.7 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Aminotran_5 PF00266.19 EWM27642.1 - 1.2e-89 300.9 0.0 1.5e-89 300.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EWM27642.1 - 2.8e-05 23.5 0.1 4.6e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EWM27642.1 - 0.0027 17.1 0.1 0.0045 16.4 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family WD40 PF00400.32 EWM27643.1 - 2.4e-51 170.6 27.9 1.7e-09 38.1 0.6 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM27643.1 - 1.2e-12 47.9 0.8 0.025 14.9 0.0 5.0 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EWM27643.1 - 6.5e-05 21.8 4.1 0.72 8.4 0.0 5.0 4 2 1 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EWM27643.1 - 0.0026 16.8 0.0 6.5 5.6 0.0 3.9 3 2 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EWM27643.1 - 0.011 15.1 0.0 3.3 6.9 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain DUF1513 PF07433.11 EWM27643.1 - 0.012 14.8 0.0 5 6.1 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) PD40 PF07676.12 EWM27643.1 - 0.051 13.5 0.6 17 5.5 0.0 4.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Med31 PF05669.12 EWM27644.1 - 1.2e-32 111.8 5.6 1.5e-32 111.4 5.6 1.1 1 0 0 1 1 1 1 SOH1 DHHC PF01529.20 EWM27645.1 - 4.6e-40 136.8 2.8 4.6e-40 136.8 2.8 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase HD_4 PF13328.6 EWM27646.1 - 1.4e-45 154.8 0.0 2.8e-45 153.8 0.0 1.5 1 0 0 1 1 1 1 HD domain RelA_SpoT PF04607.17 EWM27646.1 - 3.2e-22 79.0 0.0 5.9e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins HD PF01966.22 EWM27646.1 - 2.7e-10 40.5 0.1 7.9e-10 39.0 0.1 1.9 2 0 0 2 2 2 1 HD domain TGS PF02824.21 EWM27646.1 - 9.4e-10 38.4 0.0 3.6e-09 36.5 0.0 2.0 2 0 0 2 2 2 1 TGS domain ACT_4 PF13291.6 EWM27646.1 - 0.0064 17.1 0.0 0.14 12.8 0.0 2.9 3 0 0 3 3 3 1 ACT domain VASt PF16016.5 EWM27647.1 - 3.1e-20 73.1 1.5 5.3e-20 72.4 1.5 1.3 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain VASt PF16016.5 EWM27648.1 - 9.5e-16 58.6 2.5 1.3e-15 58.1 2.5 1.2 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain Taxilin PF09728.9 EWM27649.1 - 0.019 14.2 56.2 0.59 9.3 10.6 3.1 2 1 1 3 3 3 0 Myosin-like coiled-coil protein Spc7 PF08317.11 EWM27649.1 - 0.49 9.2 49.7 0.033 13.1 20.0 3.4 1 1 1 3 3 3 0 Spc7 kinetochore protein NPV_P10 PF05531.12 EWM27649.1 - 4.3 7.9 16.7 17 6.0 0.4 5.1 3 2 2 5 5 5 0 Nucleopolyhedrovirus P10 protein FIST PF08495.10 EWM27650.1 - 9.4e-10 38.8 0.1 0.00035 20.6 0.0 3.5 2 1 1 3 3 3 3 FIST N domain FIST_C PF10442.9 EWM27650.1 - 6.1e-07 29.5 0.0 1.3e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 FIST C domain F-box-like PF12937.7 EWM27650.1 - 0.006 16.4 0.4 0.021 14.7 0.4 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EWM27650.1 - 0.063 13.2 0.3 0.17 11.8 0.3 1.7 1 0 0 1 1 1 0 F-box domain Pur_DNA_glyco PF02245.16 EWM27651.1 - 3.2e-49 166.7 0.0 4.6e-49 166.2 0.0 1.2 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) LCM PF04072.14 EWM27652.1 - 6.6e-17 62.0 0.0 2.6e-16 60.1 0.0 1.9 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase 4HBT PF03061.22 EWM27653.1 - 8.3e-07 29.3 0.1 0.00078 19.8 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily PPR PF01535.20 EWM27654.1 - 8.5e-28 94.6 2.1 2e-05 24.5 0.1 9.1 9 0 0 9 9 9 7 PPR repeat PPR_2 PF13041.6 EWM27654.1 - 2.8e-25 88.2 0.1 0.00039 20.5 0.0 8.2 5 3 5 10 10 10 5 PPR repeat family PPR_long PF17177.4 EWM27654.1 - 3.4e-11 42.9 0.0 0.014 14.8 0.0 3.9 2 1 1 4 4 4 3 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 EWM27654.1 - 1e-10 41.5 0.0 0.086 12.9 0.0 4.9 4 1 1 5 5 5 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 EWM27654.1 - 1.7e-09 37.2 0.0 0.096 12.4 0.0 6.8 8 0 0 8 8 8 2 PPR repeat TPR_7 PF13176.6 EWM27654.1 - 0.0022 17.9 0.4 4.9 7.4 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 EWM27654.1 - 0.033 13.4 0.9 0.43 9.7 0.3 2.5 1 1 0 2 2 2 0 Tetratricopeptide repeat Smr PF01713.21 EWM27654.1 - 0.046 14.1 0.0 0.21 12.0 0.0 2.2 1 0 0 1 1 1 0 Smr domain UPRTase PF14681.6 EWM27654.1 - 0.09 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Adap_comp_sub PF00928.21 EWM27656.1 - 4.4e-87 291.8 0.0 5.6e-87 291.5 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EWM27656.1 - 6.4e-07 29.4 1.0 1.2e-06 28.5 1.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Longin PF13774.6 EWM27656.1 - 0.061 13.4 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 Regulated-SNARE-like domain DUF3748 PF12566.8 EWM27657.1 - 0.085 12.8 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3748) Myb_DNA-binding PF00249.31 EWM27658.1 - 6.9e-15 55.0 0.2 1.7e-14 53.7 0.2 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EWM27658.1 - 0.0034 17.6 0.2 0.0072 16.5 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EWM27658.1 - 0.024 14.5 0.1 0.044 13.7 0.1 1.4 1 0 0 1 1 1 0 Myb DNA-binding like OTU PF02338.19 EWM27659.1 - 5.6e-17 62.4 0.1 2.2e-16 60.5 0.0 2.0 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EWM27659.1 - 0.00012 21.6 0.0 0.11 12.0 0.0 2.2 2 0 0 2 2 2 2 Peptidase C65 Otubain SEC-C PF02810.15 EWM27659.1 - 0.0051 16.7 11.8 0.011 15.7 11.8 1.6 1 0 0 1 1 1 1 SEC-C motif Myb_DNA-binding PF00249.31 EWM27659.1 - 0.049 13.8 0.0 4.4 7.6 0.0 2.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain Plant_NMP1 PF06694.11 EWM27659.1 - 0.19 10.8 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) PRR20 PF15708.5 EWM27660.1 - 0.013 15.4 3.4 0.022 14.6 3.4 1.3 1 0 0 1 1 1 0 Proline-rich protein family 20 DUF5536 PF17688.1 EWM27660.1 - 0.19 11.6 0.3 0.41 10.5 0.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5536) DUF2997 PF11211.8 EWM27661.1 - 0.0072 16.1 1.9 0.0083 15.9 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2997) Methyltransf_16 PF10294.9 EWM27662.1 - 5.1e-08 32.8 0.0 7.7e-07 29.0 0.0 2.1 1 1 0 1 1 1 1 Lysine methyltransferase DUF1744 PF08490.12 EWM27663.1 - 9.1e-106 353.8 0.0 1.9e-105 352.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 EWM27663.1 - 1.4e-67 228.3 0.0 2e-67 227.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 EWM27663.1 - 6.6e-11 41.6 0.2 7e-10 38.2 0.2 2.6 1 1 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 EWM27663.1 - 2.4e-07 30.6 0.3 7.5e-07 29.0 0.3 1.7 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 EWM27663.1 - 7.4e-07 29.3 0.2 3.5e-06 27.1 0.0 2.3 2 0 0 2 2 2 1 RNase_H superfamily Pectate_lyase_3 PF12708.7 EWM27664.1 - 0.13 12.1 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Pectate lyase superfamily protein Aldedh PF00171.22 EWM27665.1 - 5e-113 378.1 1.2 5.9e-113 377.8 1.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TCR PF03638.15 EWM27666.1 - 1.6e-09 37.9 24.5 1.6e-09 37.9 24.5 2.1 2 0 0 2 2 2 1 Tesmin/TSO1-like CXC domain, cysteine-rich domain F-box-like PF12937.7 EWM27666.1 - 0.00038 20.3 0.0 0.00076 19.3 0.0 1.5 1 0 0 1 1 1 1 F-box-like Ribosomal_L27A PF00828.19 EWM27667.1 - 6.2e-23 81.9 0.6 8e-23 81.5 0.6 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF5026 PF16429.5 EWM27667.1 - 0.083 13.0 0.8 0.12 12.4 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5026) Acetyltransf_3 PF13302.7 EWM27668.1 - 5.9e-16 59.4 0.0 1e-15 58.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EWM27668.1 - 8.2e-10 38.9 0.0 1.4e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 EWM27668.1 - 0.014 15.0 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GlutR_N PF05201.15 EWM27669.1 - 3.2e-39 134.0 0.0 6.5e-39 133.0 0.0 1.5 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.20 EWM27669.1 - 4.7e-34 117.4 0.0 1e-33 116.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GlutR_dimer PF00745.20 EWM27669.1 - 3.3e-22 78.8 4.1 3.3e-22 78.8 2.8 1.8 2 0 0 2 2 2 1 Glutamyl-tRNAGlu reductase, dimerisation domain OCD_Mu_crystall PF02423.15 EWM27669.1 - 1.5e-05 24.1 0.0 2.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.17 EWM27669.1 - 0.0004 20.9 0.5 0.0013 19.3 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EWM27669.1 - 0.0053 16.9 0.2 0.012 15.8 0.2 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 EWM27669.1 - 0.0053 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GFO_IDH_MocA PF01408.22 EWM27669.1 - 0.021 15.7 0.0 0.067 14.0 0.0 1.9 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DBD_HTH PF18430.1 EWM27669.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Putative DNA-binding domain Polyketide_cyc PF03364.20 EWM27671.1 - 5.3e-07 29.9 0.2 9.7e-07 29.0 0.2 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 EWM27671.1 - 0.013 15.8 0.3 0.031 14.6 0.3 1.6 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport DEAD PF00270.29 EWM27673.1 - 3.9e-37 127.7 0.1 7.1e-37 126.9 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EWM27673.1 - 6.8e-25 87.6 0.0 1.6e-24 86.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EWM27673.1 - 0.005 16.9 0.0 0.016 15.2 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Presenilin PF01080.17 EWM27673.1 - 0.25 10.0 5.5 0.036 12.8 0.3 1.9 2 0 0 2 2 2 0 Presenilin Pkinase PF00069.25 EWM27674.1 - 3e-36 125.1 0.0 2.9e-25 89.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EWM27674.1 - 4e-36 124.6 0.0 5.9e-31 107.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EWM27674.1 - 3.5e-08 33.1 0.0 5.5e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EWM27674.1 - 3.2 7.6 7.4 24 4.7 7.4 2.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family TALPID3 PF15324.6 EWM27675.1 - 0.24 9.0 6.6 0.26 8.9 6.6 1.0 1 0 0 1 1 1 0 Hedgehog signalling target DAG_kinase_N PF14513.6 EWM27675.1 - 0.33 11.1 3.2 0.37 11.0 3.2 1.1 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus NAM-associated PF14303.6 EWM27675.1 - 0.76 10.5 9.5 0.78 10.5 9.5 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Apelin PF15360.6 EWM27675.1 - 5.9 7.5 6.5 17 6.1 0.3 2.5 1 1 2 3 3 3 0 APJ endogenous ligand zf-RanBP PF00641.18 EWM27676.1 - 0.001 18.3 5.6 0.0017 17.6 5.6 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Zn_clus PF00172.18 EWM27679.1 - 4.2e-06 26.8 14.3 1e-05 25.6 14.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SPX PF03105.19 EWM27679.1 - 0.71 9.7 3.7 5.6 6.8 1.7 2.1 2 0 0 2 2 2 0 SPX domain CS PF04969.16 EWM27682.1 - 9.5e-10 39.4 0.0 1.4e-09 38.9 0.0 1.2 1 0 0 1 1 1 1 CS domain LapA_dom PF06305.11 EWM27682.1 - 0.095 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DnaJ PF00226.31 EWM27683.1 - 4.5e-26 90.7 0.6 4.5e-26 90.7 0.6 1.8 2 0 0 2 2 2 1 DnaJ domain DUF1977 PF09320.11 EWM27683.1 - 4.4e-16 59.0 1.2 4.4e-16 59.0 1.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) TPR_2 PF07719.17 EWM27683.1 - 0.00036 20.4 0.4 0.0055 16.7 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EWM27683.1 - 0.063 13.1 0.2 0.18 11.7 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 EWM27683.1 - 4.9 8.3 6.2 1.7 9.7 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Ion_trans PF00520.31 EWM27685.1 - 5.1e-19 68.5 39.4 1.6e-11 43.9 20.2 2.8 2 1 1 3 3 3 2 Ion transport protein CDP-OH_P_transf PF01066.21 EWM27687.1 - 1.2e-16 61.2 0.4 1.2e-16 61.2 0.4 3.0 3 2 0 3 3 3 1 CDP-alcohol phosphatidyltransferase SRP9-21 PF05486.12 EWM27688.1 - 0.00031 21.1 0.1 0.012 16.0 0.1 2.5 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) PRY PF13765.6 EWM27688.1 - 0.077 12.6 0.1 1.6 8.4 0.0 2.2 2 0 0 2 2 2 0 SPRY-associated domain AAA PF00004.29 EWM27689.1 - 4.6e-40 137.1 0.0 9.5e-40 136.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EWM27689.1 - 6.1e-10 38.7 0.2 1.2e-09 37.9 0.2 1.4 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EWM27689.1 - 4.3e-09 36.2 0.1 8.9e-09 35.2 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 EWM27689.1 - 9.6e-06 25.9 0.3 0.0039 17.5 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 EWM27689.1 - 1.7e-05 24.9 0.1 0.00015 21.8 0.1 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 EWM27689.1 - 6e-05 22.3 0.0 9.8e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 EWM27689.1 - 7e-05 23.0 0.0 0.00014 22.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EWM27689.1 - 0.00037 20.9 0.2 0.0026 18.2 0.1 2.1 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EWM27689.1 - 0.0012 18.6 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 EWM27689.1 - 0.0029 17.0 0.1 0.26 10.6 0.1 2.2 1 1 1 2 2 2 1 KaiC IstB_IS21 PF01695.17 EWM27689.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 EWM27689.1 - 0.018 15.4 0.0 0.035 14.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.13 EWM27689.1 - 0.025 13.8 0.0 0.045 12.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_3 PF07726.11 EWM27689.1 - 0.03 14.2 0.0 0.083 12.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EWM27689.1 - 0.039 14.1 0.0 0.073 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EWM27689.1 - 0.044 13.5 0.0 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 EWM27689.1 - 0.045 13.5 0.1 0.16 11.7 0.1 1.8 2 0 0 2 2 2 0 AAA domain Prot_ATP_OB_N PF17758.1 EWM27689.1 - 0.047 13.3 1.4 0.084 12.5 0.1 2.1 3 0 0 3 3 1 0 Proteasomal ATPase OB N-terminal domain TsaE PF02367.17 EWM27689.1 - 0.072 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 EWM27689.1 - 0.081 12.1 0.0 0.75 8.9 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.6 EWM27689.1 - 0.089 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EWM27689.1 - 0.092 12.3 0.3 0.83 9.2 0.1 2.1 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EWM27689.1 - 0.096 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 EWM27689.1 - 0.1 12.5 0.1 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.16 EWM27689.1 - 0.12 11.8 0.2 0.31 10.5 0.1 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 EWM27689.1 - 0.19 11.2 0.1 0.43 10.1 0.0 1.5 2 0 0 2 2 1 0 P-loop containing dynein motor region DUF2075 PF09848.9 EWM27689.1 - 0.22 10.7 0.1 0.32 10.2 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Phos_pyr_kin PF08543.12 EWM27690.1 - 2.3e-75 253.2 0.4 3.5e-75 252.6 0.4 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TMP-TENI PF02581.17 EWM27690.1 - 1e-46 158.6 0.1 9.8e-46 155.4 0.0 2.4 3 0 0 3 3 3 1 Thiamine monophosphate synthase PfkB PF00294.24 EWM27690.1 - 1.2e-07 31.4 0.1 7.7e-06 25.4 0.0 2.2 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Carb_kinase PF01256.17 EWM27690.1 - 7.2e-05 22.4 2.1 0.06 12.8 0.8 2.5 2 1 0 2 2 2 2 Carbohydrate kinase ThiG PF05690.14 EWM27690.1 - 0.02 14.2 0.1 0.042 13.2 0.1 1.5 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG HK PF02110.15 EWM27690.1 - 0.14 11.5 0.9 0.44 9.9 0.0 2.1 3 0 0 3 3 3 0 Hydroxyethylthiazole kinase family Sod_Cu PF00080.20 EWM27691.1 - 8.2e-18 64.9 0.0 5.1e-14 52.6 0.1 2.3 2 0 0 2 2 2 2 Copper/zinc superoxide dismutase (SODC) Sod_Cu PF00080.20 EWM27692.1 - 8.3e-18 64.9 0.0 5.1e-14 52.6 0.1 2.3 2 0 0 2 2 2 2 Copper/zinc superoxide dismutase (SODC) Lipase_3 PF01764.25 EWM27693.1 - 5.4e-06 26.3 0.1 2.5e-05 24.2 0.1 2.1 1 1 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 EWM27693.1 - 0.0087 15.3 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EWM27693.1 - 0.097 12.8 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_6 PF12697.7 EWM27693.1 - 0.94 10.0 6.6 0.52 10.9 0.1 3.1 3 0 0 3 3 3 0 Alpha/beta hydrolase family GlcNAc PF11397.8 EWM27694.1 - 6.2e-63 213.4 0.1 8.7e-63 212.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) 60KD_IMP PF02096.20 EWM27696.1 - 5.7e-13 49.1 0.0 9.4e-13 48.4 0.0 1.3 1 1 0 1 1 1 1 60Kd inner membrane protein Cwf_Cwc_15 PF04889.12 EWM27697.1 - 2e-58 198.0 23.4 2.3e-58 197.8 23.4 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 EWM27697.1 - 0.16 11.4 27.7 0.22 10.9 27.7 1.2 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.12 EWM27697.1 - 1.2 7.7 26.2 1.4 7.4 26.2 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 EWM27697.1 - 2.1 6.5 26.1 2.4 6.3 26.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EWM27697.1 - 2.2 6.5 19.1 2.4 6.4 19.1 1.1 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 EWM27697.1 - 6.1 6.9 32.6 3.3 7.8 30.8 1.5 1 1 0 1 1 1 0 YL1 nuclear protein TRAPP PF04051.16 EWM27698.1 - 2.2e-35 121.5 0.1 2.6e-35 121.3 0.1 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component C_GCAxxG_C_C PF09719.10 EWM27698.1 - 0.025 14.8 0.0 2.4 8.5 0.0 2.2 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) Pro_3_hydrox_C PF05373.11 EWM27698.1 - 0.061 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 L-proline 3-hydroxylase, C-terminal MatP_C PF17414.2 EWM27698.1 - 0.17 12.1 0.1 0.36 11.1 0.1 1.5 1 0 0 1 1 1 0 MatP C-terminal ribbon-helix-helix domain RRM_1 PF00076.22 EWM27699.1 - 5.9e-22 77.3 0.0 9.7e-09 34.9 0.0 4.2 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EWM27699.1 - 6.5e-09 35.5 0.0 0.012 15.4 0.0 3.3 3 0 0 3 3 3 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 EWM27699.1 - 0.00069 19.6 0.0 5.7 7.1 0.0 3.9 3 0 0 3 3 3 2 Limkain b1 RRM_5 PF13893.6 EWM27699.1 - 0.062 12.9 0.0 13 5.4 0.0 2.5 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 2OG-FeII_Oxy PF03171.20 EWM27700.1 - 0.00015 22.2 0.1 0.00024 21.5 0.1 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EWM27700.1 - 0.11 13.3 0.0 0.18 12.6 0.0 1.4 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal Chorion_3 PF05387.11 EWM27701.1 - 0.87 9.2 5.6 1.4 8.5 5.6 1.2 1 0 0 1 1 1 0 Chorion family 3 Nuc_sug_transp PF04142.15 EWM27702.1 - 1.3e-101 339.9 18.1 5.6e-64 216.3 2.3 2.0 2 0 0 2 2 2 2 Nucleotide-sugar transporter UAA PF08449.11 EWM27702.1 - 3.2e-06 26.6 7.8 5.7e-06 25.8 0.0 2.8 2 1 1 3 3 3 2 UAA transporter family EamA PF00892.20 EWM27702.1 - 6.9e-06 26.3 3.2 6.9e-06 26.3 3.2 3.6 3 2 0 3 3 3 1 EamA-like transporter family PUNUT PF16913.5 EWM27702.1 - 0.00025 20.4 3.4 0.0005 19.4 3.4 1.4 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport Chromate_transp PF02417.15 EWM27702.1 - 8.6 6.5 13.3 0.11 12.7 2.7 2.5 2 1 0 2 2 2 0 Chromate transporter GPDPase_memb PF10110.9 EWM27703.1 - 0.025 13.3 0.0 0.029 13.2 0.0 1.1 1 0 0 1 1 1 0 Membrane domain of glycerophosphoryl diester phosphodiesterase CRAL_TRIO PF00650.20 EWM27704.1 - 1e-24 87.1 0.0 1.6e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EWM27704.1 - 2.1e-06 27.9 0.0 3.3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF5624 PF18538.1 EWM27704.1 - 0.032 14.3 0.0 0.063 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) DUF592 PF04574.13 EWM27704.1 - 0.068 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF592) Lectin_N PF03954.14 EWM27705.1 - 0.13 12.1 0.7 0.34 10.6 0.1 2.1 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain MTP18 PF10558.9 EWM27706.1 - 7.7e-16 58.5 2.4 2.8e-10 40.4 0.7 2.2 1 1 1 2 2 2 2 Mitochondrial 18 KDa protein (MTP18) CLASP_N PF12348.8 EWM27708.1 - 4.3e-05 23.2 0.1 7.1e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 CLASP N terminal Claudin_3 PF06653.11 EWM27708.1 - 0.029 14.3 1.1 0.05 13.5 1.1 1.3 1 0 0 1 1 1 0 Tight junction protein, Claudin-like DUF92 PF01940.16 EWM27709.1 - 4.6e-54 183.3 12.4 7.7e-54 182.6 12.4 1.4 1 1 0 1 1 1 1 Integral membrane protein DUF92 Ribosomal_L18A PF01775.17 EWM27710.1 - 1.2e-52 177.1 0.3 1.9e-52 176.5 0.3 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Porin_3 PF01459.22 EWM27711.1 - 8.1e-26 91.1 0.2 9.4e-26 90.9 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic porin Leukocidin PF07968.12 EWM27711.1 - 0.026 14.4 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 Leukocidin/Hemolysin toxin family JAB PF01398.21 EWM27712.1 - 1.5e-09 37.8 0.0 3.5e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 EWM27712.1 - 6.3e-06 26.0 0.8 7.5e-05 22.5 0.0 2.7 3 0 0 3 3 3 1 Prokaryotic homologs of the JAB domain PWWP PF00855.17 EWM27712.1 - 0.00031 21.1 0.2 0.00072 19.9 0.2 1.6 1 0 0 1 1 1 1 PWWP domain Mpv17_PMP22 PF04117.12 EWM27713.1 - 2.3e-14 53.3 0.9 5.8e-14 52.1 0.2 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family XAF1_C PF18608.1 EWM27713.1 - 0.029 13.9 0.3 0.057 13.0 0.3 1.5 1 0 0 1 1 1 0 XIAP-associated factor 1 C-terminal domain Methyltransf_21 PF05050.12 EWM27714.1 - 3.5e-09 36.9 0.0 1.5e-08 34.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_23 PF13489.6 EWM27714.1 - 0.014 15.2 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EWM27714.1 - 0.041 14.6 0.0 0.086 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 EWM27714.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) APOBEC1 PF18769.1 EWM27714.1 - 0.14 12.5 0.0 0.58 10.4 0.0 2.1 2 0 0 2 2 2 0 APOBEC1 AAA PF00004.29 EWM27715.1 - 8e-54 181.6 0.0 1e-32 113.3 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EWM27715.1 - 3.2e-20 71.7 0.8 4.4e-10 39.2 0.1 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EWM27715.1 - 6.8e-12 46.1 8.7 0.00066 20.1 0.1 4.9 3 2 2 5 5 4 3 AAA ATPase domain IstB_IS21 PF01695.17 EWM27715.1 - 1.7e-08 34.4 0.0 0.0019 18.0 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.12 EWM27715.1 - 1.9e-07 31.2 4.1 4.3e-05 23.5 0.5 3.2 2 2 1 3 3 3 1 NACHT domain AAA_5 PF07728.14 EWM27715.1 - 3.2e-07 30.4 0.0 0.0061 16.6 0.1 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EWM27715.1 - 3.5e-07 30.8 0.0 0.017 15.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 EWM27715.1 - 8.3e-07 29.3 0.0 0.0027 17.8 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 EWM27715.1 - 9.3e-07 28.4 0.1 0.0048 16.2 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_25 PF13481.6 EWM27715.1 - 4.6e-06 26.3 0.7 0.0009 18.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EWM27715.1 - 4.8e-06 26.9 2.8 0.01 16.1 0.1 3.8 2 2 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EWM27715.1 - 6.2e-06 26.5 4.2 0.063 13.5 0.1 3.2 2 1 1 3 3 3 2 AAA domain RuvB_N PF05496.12 EWM27715.1 - 2.5e-05 24.1 0.0 0.3 10.8 0.0 2.7 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EWM27715.1 - 4e-05 23.8 0.0 0.24 11.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 EWM27715.1 - 0.00014 21.8 0.1 0.36 10.8 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 EWM27715.1 - 0.0002 21.1 0.1 0.0084 15.8 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_24 PF13479.6 EWM27715.1 - 0.0005 19.8 0.0 0.078 12.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EWM27715.1 - 0.00053 19.8 0.8 0.41 10.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EWM27715.1 - 0.00078 19.8 0.1 0.4 11.1 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 EWM27715.1 - 0.001 18.6 0.0 0.82 9.1 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_29 PF13555.6 EWM27715.1 - 0.0014 18.3 0.5 0.36 10.6 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain ATPase PF06745.13 EWM27715.1 - 0.0018 17.7 0.0 0.1 12.0 0.0 2.3 2 0 0 2 2 2 1 KaiC Mg_chelatase PF01078.21 EWM27715.1 - 0.0019 17.6 1.3 0.49 9.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 EWM27715.1 - 0.0021 18.6 0.1 0.39 11.2 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_14 PF13173.6 EWM27715.1 - 0.0059 16.6 0.0 0.73 9.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 EWM27715.1 - 0.0084 15.4 0.7 2.9 7.1 0.1 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 EWM27715.1 - 0.013 14.6 0.0 0.076 12.1 0.0 2.2 2 1 0 2 2 2 0 Type II/IV secretion system protein AAA_17 PF13207.6 EWM27715.1 - 0.014 15.9 0.3 0.98 9.8 0.1 2.6 2 0 0 2 2 2 0 AAA domain Hpr_kinase_C PF07475.12 EWM27715.1 - 0.027 14.0 0.4 0.38 10.3 0.0 2.2 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain CPT PF07931.12 EWM27715.1 - 0.031 14.1 0.1 6 6.7 0.0 2.6 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein DUF815 PF05673.13 EWM27715.1 - 0.034 13.3 0.0 0.84 8.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_19 PF13245.6 EWM27715.1 - 0.055 13.8 0.6 9.7 6.5 0.2 2.4 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EWM27715.1 - 0.056 12.9 2.2 0.14 11.5 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein RecA PF00154.21 EWM27715.1 - 0.06 12.8 0.0 0.099 12.1 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein Viral_helicase1 PF01443.18 EWM27715.1 - 0.089 12.5 0.0 0.62 9.8 0.0 2.3 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_21 PF13304.6 EWM27715.1 - 0.13 12.1 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system PduV-EutP PF10662.9 EWM27715.1 - 0.14 11.9 0.0 2.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_11 PF13086.6 EWM27715.1 - 0.15 11.8 0.0 3 7.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_6 PF12774.7 EWM27715.1 - 0.21 10.5 0.1 10 5.0 0.0 2.1 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Zeta_toxin PF06414.12 EWM27715.1 - 0.32 10.3 2.4 1.8 7.8 0.5 2.3 2 0 0 2 2 2 0 Zeta toxin CbiA PF01656.23 EWM27715.1 - 0.69 10.0 1.9 2.1 8.4 0.2 2.4 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain U-box PF04564.15 EWM27716.1 - 2.7e-17 62.7 0.0 4.8e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 U-box domain FHA PF00498.26 EWM27716.1 - 7.5e-17 61.4 0.0 4.2e-07 30.2 0.1 2.4 2 0 0 2 2 2 2 FHA domain zf-Nse PF11789.8 EWM27716.1 - 2.6e-05 23.9 0.0 4.8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 EWM27716.1 - 0.0004 20.5 0.0 0.0011 19.0 0.0 1.7 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein Yop-YscD_cpl PF16697.5 EWM27716.1 - 0.0074 16.6 0.0 0.22 11.9 0.0 2.6 2 1 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Cellulase PF00150.18 EWM27718.1 - 6.1e-14 52.1 0.5 9.3e-14 51.5 0.5 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MatE PF01554.18 EWM27720.1 - 2.8e-36 124.6 15.8 2.6e-23 82.5 5.0 2.5 2 0 0 2 2 2 2 MatE Polysacc_synt PF01943.17 EWM27720.1 - 0.03 13.7 7.2 0.98 8.7 0.8 2.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein PPR_2 PF13041.6 EWM27721.1 - 1.4e-53 178.8 0.0 2.9e-10 40.2 0.0 12.0 10 2 3 13 13 13 9 PPR repeat family PPR PF01535.20 EWM27721.1 - 2.3e-41 137.2 15.7 0.00022 21.3 0.0 15.4 16 1 0 16 16 16 9 PPR repeat PPR_3 PF13812.6 EWM27721.1 - 2.4e-33 114.0 0.0 7.1e-08 32.4 0.0 9.8 7 3 3 10 10 10 7 Pentatricopeptide repeat domain PPR_1 PF12854.7 EWM27721.1 - 2.3e-30 104.0 3.5 2.2e-07 30.4 0.0 9.6 10 1 0 10 10 10 6 PPR repeat PPR_long PF17177.4 EWM27721.1 - 3.4e-12 46.2 6.7 1.4e-05 24.6 0.4 5.1 5 2 1 6 6 6 4 Pentacotripeptide-repeat region of PRORP Smr PF01713.21 EWM27721.1 - 3.3e-06 27.4 0.0 1.5e-05 25.2 0.0 2.2 2 0 0 2 2 2 1 Smr domain TPR_19 PF14559.6 EWM27721.1 - 0.0051 17.3 0.6 0.35 11.4 0.0 4.0 3 1 2 5 5 5 1 Tetratricopeptide repeat Glyco_trans_4_3 PF12000.8 EWM27721.1 - 0.13 11.9 0.1 2.5 7.8 0.1 2.7 1 1 1 2 2 2 0 Glycosyl transferase family 4 group ELYS PF13934.6 EWM27721.1 - 0.61 10.0 4.4 11 5.9 0.1 3.9 4 1 1 5 5 5 0 Nuclear pore complex assembly RMI1_N PF08585.12 EWM27722.1 - 8.3e-32 110.7 0.1 3.5e-19 69.4 0.3 2.4 1 1 1 2 2 2 2 RecQ mediated genome instability protein RMI1_C PF16099.5 EWM27722.1 - 1.1e-06 28.5 0.0 2.3e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Recq-mediated genome instability protein 1, C-terminal OB-fold Pkr1 PF08636.10 EWM27723.1 - 5.4e-10 39.3 1.4 1e-09 38.4 1.4 1.4 1 0 0 1 1 1 1 ER protein Pkr1 TspO_MBR PF03073.15 EWM27723.1 - 0.0075 16.3 0.6 0.012 15.7 0.6 1.3 1 0 0 1 1 1 1 TspO/MBR family DUF5418 PF17439.2 EWM27723.1 - 0.012 15.7 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5418) DUF1772 PF08592.11 EWM27723.1 - 0.26 11.6 4.1 0.12 12.7 0.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) TPR_12 PF13424.6 EWM27724.1 - 6e-20 71.3 1.7 5.5e-11 42.6 0.2 2.4 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 EWM27724.1 - 3.4e-19 68.1 7.6 7.4e-10 38.4 0.3 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EWM27724.1 - 5.6e-05 23.0 0.5 0.0011 19.1 0.2 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EWM27724.1 - 0.00022 21.8 2.2 0.00061 20.4 0.2 2.8 3 1 0 3 3 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EWM27724.1 - 0.00037 20.4 1.4 0.0032 17.4 0.6 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 EWM27724.1 - 0.001 19.5 1.6 0.19 12.4 0.0 3.7 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EWM27724.1 - 0.0015 18.0 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 MalT-like TPR region TPR_1 PF00515.28 EWM27724.1 - 0.003 17.3 0.5 0.023 14.5 0.3 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EWM27724.1 - 0.0072 16.6 2.5 0.32 11.5 0.0 3.7 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EWM27724.1 - 0.089 12.5 0.1 0.31 10.8 0.2 1.9 2 1 0 2 2 2 0 TPR repeat TPR_7 PF13176.6 EWM27724.1 - 0.22 11.6 8.0 1.9 8.7 0.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 EWM27724.1 - 1.3 10.0 4.4 8.5 7.5 0.2 3.1 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EWM27725.1 - 1.5e-33 114.9 8.8 7.9e-11 42.1 0.1 4.3 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 EWM27725.1 - 7.6e-27 92.4 24.7 1.2e-09 37.8 0.3 7.6 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 EWM27725.1 - 5.1e-08 33.4 4.9 0.001 19.7 0.2 5.1 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EWM27725.1 - 2.3e-07 30.3 8.8 0.035 13.9 0.3 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EWM27725.1 - 5.1e-06 26.2 13.1 0.0049 16.9 0.6 5.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 EWM27725.1 - 1.1e-05 25.4 3.2 0.48 10.9 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EWM27725.1 - 1.7e-05 24.4 3.5 0.41 10.4 0.1 3.9 3 0 0 3 3 3 3 TPR repeat TPR_MalT PF17874.1 EWM27725.1 - 0.00052 19.5 1.4 0.0046 16.4 0.1 2.2 1 1 0 2 2 2 1 MalT-like TPR region TPR_8 PF13181.6 EWM27725.1 - 0.0016 18.5 0.2 0.0016 18.5 0.2 4.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.14 EWM27725.1 - 0.0027 18.2 2.3 0.28 11.9 0.0 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EWM27725.1 - 0.34 11.0 15.8 2.9 8.1 0.2 5.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 EWM27725.1 - 0.78 10.7 6.2 11 7.1 0.1 4.3 4 1 1 5 5 4 0 Tetratricopeptide repeat OHCU_decarbox PF09349.10 EWM27727.1 - 6.7e-30 104.6 0.0 9.4e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 OHCU decarboxylase SAP PF02037.27 EWM27728.1 - 7.2e-06 25.6 0.4 1.2e-05 25.0 0.4 1.3 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 EWM27728.1 - 0.0021 17.8 0.1 0.0033 17.1 0.1 1.4 1 0 0 1 1 1 1 HeH/LEM domain adh_short PF00106.25 EWM27730.1 - 6.1e-23 81.3 0.0 8.6e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EWM27730.1 - 1.1e-17 64.4 0.0 1.6e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase YccJ PF13993.6 EWM27730.1 - 0.2 12.0 0.0 0.45 10.9 0.0 1.5 1 0 0 1 1 1 0 YccJ-like protein ACPS PF01648.20 EWM27731.1 - 1.1e-13 51.3 0.0 5.8e-13 49.0 0.0 2.1 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily DUF765 PF05570.11 EWM27731.1 - 0.064 13.4 0.2 0.064 13.4 0.2 2.3 2 0 0 2 2 2 0 Circovirus protein of unknown function (DUF765) Ribonuc_red_lgC PF02867.15 EWM27732.1 - 3.4e-184 613.2 0.0 4.2e-184 612.9 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EWM27732.1 - 5.7e-24 83.9 0.1 2e-23 82.2 0.1 2.0 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EWM27732.1 - 3.6e-17 62.7 0.0 1.3e-16 61.0 0.0 2.0 1 0 0 1 1 1 1 ATP cone domain Hom_end_hint PF05203.16 EWM27732.1 - 0.017 15.1 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 Hom_end-associated Hint DUF3228 PF11539.8 EWM27735.1 - 2.2e-78 262.2 0.0 2.6e-78 262.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) Thioredoxin PF00085.20 EWM27735.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin CDC73_C PF05179.14 EWM27736.1 - 8.2e-42 142.6 0.1 1.3e-41 141.9 0.1 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 EWM27736.1 - 3e-07 30.1 0.1 7.4e-07 28.8 0.1 1.7 1 1 0 1 1 1 1 Paf1 complex subunit CDC73 N-terminal HEAT PF02985.22 EWM27737.1 - 1.4e-14 52.9 20.7 0.005 17.0 0.2 11.0 11 0 0 11 11 11 4 HEAT repeat HEAT_EZ PF13513.6 EWM27737.1 - 3.8e-14 52.8 40.2 0.00054 20.4 0.0 11.1 11 3 2 13 13 13 5 HEAT-like repeat HEAT_2 PF13646.6 EWM27737.1 - 2.4e-10 40.7 8.5 0.072 13.5 0.0 6.7 3 3 4 7 7 7 5 HEAT repeats Vac14_Fab1_bd PF12755.7 EWM27737.1 - 2.9e-08 34.2 0.0 0.015 15.9 0.0 4.5 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EWM27737.1 - 3.2e-08 33.8 0.0 0.31 11.1 0.0 4.4 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 EWM27737.1 - 2.3e-06 27.4 0.1 2.6e-05 24.0 0.0 2.9 2 1 1 3 3 3 1 Importin-beta N-terminal domain Arm PF00514.23 EWM27737.1 - 0.00028 20.8 11.3 0.11 12.6 0.2 6.2 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 EWM27737.1 - 0.007 15.0 0.0 3.4 6.1 0.0 3.1 3 0 0 3 3 3 2 Adaptin N terminal region CLASP_N PF12348.8 EWM27737.1 - 0.017 14.7 0.1 3.1 7.3 0.0 3.7 3 1 0 3 3 3 0 CLASP N terminal DUF3510 PF12022.8 EWM27738.1 - 3.2e-28 98.7 0.0 9.1e-28 97.2 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) COG2 PF06148.11 EWM27738.1 - 1.8e-22 79.9 0.8 1.8e-22 79.9 0.8 1.8 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 RPN1_RPN2_N PF17781.1 EWM27740.1 - 3.3e-116 388.0 0.4 5.1e-116 387.4 0.4 1.3 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain PC_rep PF01851.22 EWM27740.1 - 3.5e-23 80.8 15.5 1.1e-06 28.8 0.5 6.7 7 0 0 7 7 7 4 Proteasome/cyclosome repeat RPN1_C PF18051.1 EWM27740.1 - 3.1e-20 71.9 0.1 6.9e-20 70.8 0.1 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal HEAT_2 PF13646.6 EWM27740.1 - 2.2e-06 27.9 16.0 0.0059 17.0 1.4 5.6 4 1 1 6 6 6 3 HEAT repeats Adaptin_N PF01602.20 EWM27740.1 - 3e-05 22.8 0.1 0.79 8.2 0.0 3.8 3 1 1 4 4 4 2 Adaptin N terminal region HEAT_EZ PF13513.6 EWM27740.1 - 0.00011 22.6 0.3 0.057 13.9 0.1 3.8 2 0 0 2 2 2 1 HEAT-like repeat HEAT PF02985.22 EWM27740.1 - 0.0002 21.4 0.2 19 5.9 0.0 5.2 5 0 0 5 5 4 0 HEAT repeat TPR_15 PF13429.6 EWM27740.1 - 0.0014 17.9 0.7 0.0034 16.6 0.7 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Utp13 PF08625.11 EWM27740.1 - 0.0042 17.0 1.2 0.019 14.9 0.2 2.4 2 0 0 2 2 2 1 Utp13 specific WD40 associated domain Cnd1 PF12717.7 EWM27740.1 - 0.0067 16.5 0.0 2.1 8.4 0.0 2.8 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 EWM27740.1 - 0.027 14.5 5.1 2.9 8.1 0.0 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Rieske PF00355.26 EWM27741.1 - 4.6e-18 64.9 0.0 8.3e-18 64.1 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 EWM27741.1 - 1.9e-15 56.7 0.6 5.1e-15 55.4 0.1 1.9 2 0 0 2 2 2 1 Pheophorbide a oxygenase GPP34 PF05719.11 EWM27741.1 - 0.066 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) Actin PF00022.19 EWM27742.1 - 2.3e-34 118.7 0.0 7e-34 117.1 0.0 1.8 1 0 0 1 1 1 1 Actin Pex24p PF06398.11 EWM27742.1 - 0.034 13.2 1.0 4.2 6.2 0.0 2.6 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin HALZ PF02183.18 EWM27742.1 - 0.063 13.5 5.9 0.72 10.1 0.4 4.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF365 PF04033.12 EWM27742.1 - 3.8 7.8 7.9 2.1 8.6 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF365) Aldedh PF00171.22 EWM27743.1 - 1.1e-165 551.7 0.0 1.2e-165 551.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Lambda_CIII PF02061.16 EWM27743.1 - 0.056 13.5 0.1 0.16 12.1 0.1 1.8 1 0 0 1 1 1 0 Lambda Phage CIII Na_H_Exchanger PF00999.21 EWM27744.1 - 9.2e-60 202.4 40.7 1.5e-59 201.7 40.7 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 EWM27744.1 - 3.1e-24 85.4 0.0 6e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Glutaredoxin PF00462.24 EWM27744.1 - 0.013 15.7 0.1 0.2 11.9 0.0 2.5 2 0 0 2 2 2 0 Glutaredoxin TFIIA PF03153.13 EWM27744.1 - 0.099 12.6 15.6 0.15 12.1 15.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 EWM27744.1 - 0.17 12.5 11.2 0.29 11.8 11.2 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1394 PF07159.12 EWM27745.1 - 9.6e-58 195.8 0.0 1.2e-57 195.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) RETICULATA-like PF11891.8 EWM27746.1 - 3e-39 134.7 0.5 4e-36 124.5 0.5 2.2 1 1 0 1 1 1 1 Protein RETICULATA-related TPD PF14811.6 EWM27747.1 - 1.8e-37 128.2 0.0 4.8e-37 126.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function TPD sequence-motif HTH_38 PF13936.6 EWM27747.1 - 0.028 14.2 0.0 0.068 13.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 EWM27747.1 - 0.07 12.9 0.1 0.32 10.9 0.1 2.2 2 0 0 2 2 2 0 Homeodomain-like domain MaoC_dehydratas PF01575.19 EWM27749.1 - 1.8e-26 92.1 0.0 2.5e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 MaoC like domain Rab5-bind PF09311.11 EWM27753.1 - 0.00092 18.7 7.1 0.0014 18.1 7.1 1.1 1 0 0 1 1 1 1 Rabaptin-like protein DUF812 PF05667.11 EWM27753.1 - 0.011 14.6 3.2 0.016 14.1 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Golgin_A5 PF09787.9 EWM27753.1 - 0.038 13.5 7.3 0.058 12.9 7.3 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Tropomyosin_1 PF12718.7 EWM27753.1 - 0.042 14.0 10.9 0.064 13.4 10.9 1.2 1 0 0 1 1 1 0 Tropomyosin like HJURP_C PF12347.8 EWM27753.1 - 0.064 13.3 0.2 0.064 13.3 0.2 2.5 2 0 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat Jnk-SapK_ap_N PF09744.9 EWM27753.1 - 0.12 12.6 11.3 0.2 11.9 11.3 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Sas10 PF09368.10 EWM27753.1 - 1.1 9.8 8.9 0.55 10.7 6.3 1.9 1 1 0 1 1 1 0 Sas10 C-terminal domain DUF724 PF05266.14 EWM27753.1 - 1.7 8.4 7.8 2.7 7.8 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Occludin_ELL PF07303.13 EWM27753.1 - 1.9 9.3 9.2 3.4 8.4 9.2 1.3 1 0 0 1 1 1 0 Occludin homology domain NUDIX PF00293.28 EWM27754.1 - 5.9e-21 74.9 0.1 9.6e-21 74.2 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain Nudix_hydro PF18290.1 EWM27754.1 - 4.2e-18 65.1 0.0 9.2e-18 64.0 0.0 1.6 1 0 0 1 1 1 1 Nudix hydrolase domain GDP_Man_Dehyd PF16363.5 EWM27755.1 - 3.8e-28 98.9 0.0 6.3e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EWM27755.1 - 1.9e-23 83.2 0.0 2.5e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EWM27755.1 - 3.2e-07 29.6 0.0 4.4e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EWM27755.1 - 1.1e-06 28.0 0.0 0.039 13.1 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 EWM27755.1 - 1.8e-06 27.3 0.1 8.9e-06 25.0 0.1 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EWM27755.1 - 0.0017 17.6 0.0 0.0025 17.0 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 EWM27755.1 - 0.0022 17.5 0.0 0.0045 16.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Reprolysin_3 PF13582.6 EWM27755.1 - 0.02 15.4 2.6 0.025 15.1 0.1 2.2 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like KR PF08659.10 EWM27755.1 - 0.052 13.4 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 KR domain DUF2325 PF10087.9 EWM27755.1 - 0.087 13.0 1.2 0.26 11.4 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) UDPG_MGDP_dh_N PF03721.14 EWM27755.1 - 0.19 11.3 0.1 0.29 10.7 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HSF_DNA-bind PF00447.17 EWM27756.1 - 6e-17 62.1 0.2 1e-16 61.3 0.2 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding PX PF00787.24 EWM27757.1 - 2e-24 85.7 0.0 3.8e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 EWM27757.1 - 4.7e-11 42.7 0.0 8.8e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Vps5 C terminal like Spo7 PF03907.13 EWM27759.1 - 0.0018 17.8 0.2 0.0024 17.4 0.2 1.1 1 0 0 1 1 1 1 Spo7-like protein DUF2116 PF09889.9 EWM27759.1 - 0.089 12.8 2.2 0.15 12.1 2.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Beach PF02138.18 EWM27760.1 - 5.5e-110 367.1 0.0 7.2e-110 366.7 0.0 1.1 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 EWM27760.1 - 2e-13 50.6 0.9 0.00088 20.0 0.1 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat PH_BEACH PF14844.6 EWM27760.1 - 2.5e-07 30.7 0.5 4.6e-05 23.4 0.1 3.4 3 1 0 3 3 3 1 PH domain associated with Beige/BEACH GRAM PF02893.20 EWM27760.1 - 0.014 15.2 0.0 8.7 6.3 0.0 2.8 3 0 0 3 3 3 0 GRAM domain NACHT PF05729.12 EWM27760.1 - 0.1 12.5 0.0 0.34 10.8 0.0 1.8 2 0 0 2 2 2 0 NACHT domain ANAPC4_WD40 PF12894.7 EWM27760.1 - 0.13 12.6 0.0 12 6.3 0.0 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF382 PF04037.13 EWM27761.1 - 3.1e-53 179.3 0.5 7.4e-53 178.1 0.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.16 EWM27761.1 - 1.7e-18 66.2 6.0 4.2e-18 64.9 6.0 1.8 1 0 0 1 1 1 1 PSP GDP_Man_Dehyd PF16363.5 EWM27762.1 - 2e-16 60.4 0.0 7.8e-16 58.4 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EWM27762.1 - 2.1e-14 53.6 0.0 3.1e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family FAST_1 PF06743.15 EWM27763.1 - 4.4e-16 58.6 0.0 0.0027 17.6 0.0 5.0 3 1 2 5 5 5 5 FAST kinase-like protein, subdomain 1 TRAPPC9-Trs120 PF08626.11 EWM27764.1 - 1.1e-05 23.1 0.0 1.3e-05 22.9 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Glyco_hydro_3 PF00933.21 EWM27766.1 - 3.5e-59 200.8 0.0 4.5e-59 200.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EWM27766.1 - 6.4e-39 134.0 0.0 9.6e-39 133.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 EWM27766.1 - 1.2e-09 38.1 0.0 2.5e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Lipase_3 PF01764.25 EWM27768.1 - 7.8e-13 48.5 0.0 2.6e-10 40.3 0.0 2.3 1 1 1 2 2 2 2 Lipase (class 3) Abhydrolase_3 PF07859.13 EWM27768.1 - 0.11 12.4 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Pan3_PK PF18101.1 EWM27769.1 - 2e-14 53.7 0.0 3.2e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 EWM27769.1 - 1.6e-07 31.0 0.0 2.4e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Cofilin_ADF PF00241.20 EWM27770.1 - 1.7e-34 118.2 0.0 2.1e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein EF-hand_4 PF12763.7 EWM27771.1 - 7.4e-10 38.7 0.0 1.5e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand DUF812 PF05667.11 EWM27771.1 - 0.00068 18.7 4.3 0.00085 18.3 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) EF-hand_1 PF00036.32 EWM27771.1 - 0.001 18.5 0.0 0.27 10.9 0.0 2.4 2 0 0 2 2 2 1 EF hand WEMBL PF05701.11 EWM27771.1 - 0.028 13.1 24.0 0.04 12.6 24.0 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Fez1 PF06818.15 EWM27771.1 - 0.038 14.4 14.1 0.064 13.7 14.1 1.4 1 0 0 1 1 1 0 Fez1 EF-hand_6 PF13405.6 EWM27771.1 - 0.13 12.3 0.0 26 5.1 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain ZapB PF06005.12 EWM27771.1 - 0.17 12.3 20.0 1.3 9.5 2.2 3.6 1 1 2 3 3 3 0 Cell division protein ZapB Laminin_II PF06009.12 EWM27771.1 - 0.2 11.7 6.7 0.36 10.9 3.8 2.2 1 1 0 2 2 2 0 Laminin Domain II DUF4407 PF14362.6 EWM27771.1 - 0.28 10.5 24.3 0.043 13.2 12.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) KASH_CCD PF14662.6 EWM27771.1 - 0.35 10.7 15.8 0.26 11.1 13.6 1.8 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH YabA PF06156.13 EWM27771.1 - 0.36 11.5 8.0 3.6 8.3 0.9 2.5 1 1 1 2 2 2 0 Initiation control protein YabA AIP3 PF03915.13 EWM27771.1 - 0.41 9.7 6.2 1.1 8.3 6.2 1.7 1 1 0 1 1 1 0 Actin interacting protein 3 ERM PF00769.19 EWM27771.1 - 2.4 7.9 28.5 0.44 10.3 13.9 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family CENP-F_leu_zip PF10473.9 EWM27771.1 - 3.5 7.6 18.8 0.059 13.4 4.3 3.0 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rx_N PF18052.1 EWM27771.1 - 3.8 7.9 7.0 8.3 6.8 0.1 3.1 1 1 2 3 3 3 0 Rx N-terminal domain DUF2968 PF11180.8 EWM27771.1 - 4.1 7.0 19.7 5.8 6.5 1.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) ADIP PF11559.8 EWM27771.1 - 6.2 6.9 17.1 4.9 7.2 1.7 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding GAS PF13851.6 EWM27771.1 - 9 5.6 15.4 84 2.4 15.4 2.2 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Orn_Arg_deC_N PF02784.16 EWM27772.1 - 2e-27 96.1 0.0 2.8e-26 92.4 0.0 2.6 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EWM27772.1 - 2.7e-08 33.9 0.0 3.5e-08 33.6 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Hexapep PF00132.24 EWM27773.1 - 3e-08 33.1 8.5 0.024 14.4 0.1 4.3 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EWM27773.1 - 0.095 12.5 0.3 0.095 12.5 0.3 2.9 3 1 1 4 4 4 0 Hexapeptide repeat of succinyl-transferase Utp8 PF10395.9 EWM27774.1 - 0.0013 17.3 0.5 0.0016 17.1 0.5 1.0 1 0 0 1 1 1 1 Utp8 family Lep_receptor_Ig PF06328.11 EWM27774.1 - 0.14 12.1 0.1 0.22 11.5 0.1 1.3 1 0 0 1 1 1 0 Ig-like C2-type domain IF3_C PF00707.22 EWM27775.1 - 3.3e-26 91.1 1.1 5.2e-26 90.4 1.1 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 EWM27775.1 - 1.4e-21 76.5 0.1 2.5e-21 75.7 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain mIF3 PF14877.6 EWM27775.1 - 0.0026 17.4 2.6 0.004 16.8 2.6 1.3 1 0 0 1 1 1 1 Mitochondrial translation initiation factor Pterin_bind PF00809.22 EWM27776.1 - 1e-78 264.4 0.3 1.4e-78 264.0 0.3 1.1 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 EWM27776.1 - 3e-27 95.4 0.0 7.7e-27 94.0 0.0 1.7 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) XPG_I PF00867.18 EWM27777.1 - 6.1e-25 87.4 0.0 1e-24 86.7 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EWM27777.1 - 3.3e-19 69.2 0.0 5.6e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 EWM27777.1 - 4.9e-05 22.9 0.0 7.4e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 EWM27777.1 - 0.027 15.1 0.0 0.057 14.0 0.0 1.5 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold XRN_M PF17846.1 EWM27777.1 - 0.05 12.6 0.0 0.069 12.1 0.0 1.2 1 0 0 1 1 1 0 Xrn1 helical domain TPR_3 PF07720.12 EWM27777.1 - 0.081 13.0 0.0 0.28 11.2 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA PF00004.29 EWM27778.1 - 5.3e-94 311.6 0.0 2.4e-45 154.2 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EWM27778.1 - 1.4e-24 85.6 10.5 2.1e-12 46.7 1.2 2.9 3 0 0 3 3 2 2 AAA+ lid domain CDC48_N PF02359.18 EWM27778.1 - 2e-13 50.3 0.0 4.9e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 EWM27778.1 - 2.3e-13 50.2 0.0 2.9e-05 23.9 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EWM27778.1 - 6.5e-13 49.4 0.1 7.4e-05 23.2 0.0 3.8 2 2 1 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 EWM27778.1 - 3.8e-11 43.4 0.0 2.6e-05 24.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EWM27778.1 - 2.1e-10 40.7 0.0 2.5e-05 24.3 0.0 3.4 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EWM27778.1 - 2.3e-10 40.8 0.0 0.0004 20.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 EWM27778.1 - 1e-08 34.8 0.0 0.002 17.4 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 EWM27778.1 - 1.3e-08 35.2 0.2 0.056 13.7 0.0 3.9 2 2 2 4 4 4 2 AAA domain Mg_chelatase PF01078.21 EWM27778.1 - 1.5e-07 31.0 0.2 0.0097 15.3 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI CDC48_2 PF02933.17 EWM27778.1 - 2.3e-07 30.5 0.0 5.8e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_18 PF13238.6 EWM27778.1 - 2.5e-07 31.3 0.0 0.039 14.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EWM27778.1 - 8.5e-07 29.3 0.0 0.032 14.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 EWM27778.1 - 1.8e-06 28.0 0.0 0.035 14.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.6 EWM27778.1 - 4.2e-06 27.2 0.0 0.085 13.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EWM27778.1 - 6.7e-06 26.4 0.0 0.2 11.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 EWM27778.1 - 7.5e-06 25.8 0.0 0.16 11.7 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Viral_helicase1 PF01443.18 EWM27778.1 - 1.4e-05 24.9 0.0 0.0076 16.0 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ATPase PF06745.13 EWM27778.1 - 2.9e-05 23.5 0.0 0.31 10.4 0.0 2.7 2 1 0 3 3 3 2 KaiC AAA_7 PF12775.7 EWM27778.1 - 3.4e-05 23.4 0.0 0.24 10.9 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region NACHT PF05729.12 EWM27778.1 - 4.2e-05 23.5 0.1 0.57 10.1 0.0 3.1 3 0 0 3 3 3 2 NACHT domain ABC_tran PF00005.27 EWM27778.1 - 4.5e-05 24.0 0.0 0.41 11.2 0.0 3.1 3 0 0 3 3 2 2 ABC transporter AAA_24 PF13479.6 EWM27778.1 - 5.5e-05 23.0 0.0 0.079 12.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 EWM27778.1 - 6e-05 23.0 0.0 0.19 11.8 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Vps4_C PF09336.10 EWM27778.1 - 6.6e-05 22.8 0.2 0.00051 20.0 0.0 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_25 PF13481.6 EWM27778.1 - 0.00016 21.4 0.8 0.7 9.4 0.1 3.3 2 1 1 3 3 3 2 AAA domain Zeta_toxin PF06414.12 EWM27778.1 - 0.00027 20.3 0.0 0.68 9.2 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin Parvo_NS1 PF01057.17 EWM27778.1 - 0.00032 19.9 0.1 0.55 9.3 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ATPase_2 PF01637.18 EWM27778.1 - 0.00033 20.6 0.1 1.3 8.9 0.0 2.8 2 1 0 2 2 2 2 ATPase domain predominantly from Archaea DUF815 PF05673.13 EWM27778.1 - 0.0005 19.3 0.0 0.72 9.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Bac_DnaA PF00308.18 EWM27778.1 - 0.00068 19.5 0.0 0.7 9.7 0.0 2.4 2 0 0 2 2 2 1 Bacterial dnaA protein Sigma54_activat PF00158.26 EWM27778.1 - 0.0007 19.3 0.0 0.64 9.7 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain NB-ARC PF00931.22 EWM27778.1 - 0.0013 18.0 0.0 1 8.5 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain AAA_3 PF07726.11 EWM27778.1 - 0.0018 18.2 0.0 2.7 7.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Cytidylate_kin2 PF13189.6 EWM27778.1 - 0.0022 18.2 1.2 1.2 9.2 0.0 3.0 3 1 0 3 3 2 1 Cytidylate kinase-like family PhoH PF02562.16 EWM27778.1 - 0.0022 17.5 0.4 2.5 7.5 0.0 2.7 2 0 0 2 2 2 2 PhoH-like protein Rad17 PF03215.15 EWM27778.1 - 0.0034 17.3 0.0 0.41 10.5 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 EWM27778.1 - 0.0056 16.8 0.0 4.2 7.5 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain SKI PF01202.22 EWM27778.1 - 0.0073 16.4 0.1 5.4 7.1 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase AAA_19 PF13245.6 EWM27778.1 - 0.01 16.2 0.3 2.7 8.3 0.1 3.2 3 1 0 3 3 3 0 AAA domain DUF2075 PF09848.9 EWM27778.1 - 0.014 14.6 0.0 1.8 7.7 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Cytidylate_kin PF02224.18 EWM27778.1 - 0.029 14.1 0.1 4.8 6.9 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase AAA_11 PF13086.6 EWM27778.1 - 0.038 13.8 0.0 7.7 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EWM27778.1 - 0.069 12.9 1.5 2.8 7.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 EWM27778.1 - 0.07 13.0 0.0 17 5.3 0.0 2.6 2 0 0 2 2 2 0 NTPase TniB PF05621.11 EWM27778.1 - 0.072 12.5 0.0 3.2 7.1 0.0 2.8 3 1 0 3 3 2 0 Bacterial TniB protein AAA_29 PF13555.6 EWM27778.1 - 0.086 12.6 0.0 3.9 7.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain RecA PF00154.21 EWM27778.1 - 0.1 12.1 0.0 7.5 5.9 0.0 2.8 3 0 0 3 3 3 0 recA bacterial DNA recombination protein CPT PF07931.12 EWM27778.1 - 0.12 12.2 0.0 1.4 8.7 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein PduV-EutP PF10662.9 EWM27778.1 - 0.15 11.8 0.0 13 5.5 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Hydin_ADK PF17213.3 EWM27778.1 - 3.1 8.0 9.5 4.4 7.5 0.0 4.0 5 0 0 5 5 3 0 Hydin Adenylate kinase-like domain Pan3_PK PF18101.1 EWM27779.1 - 0.00041 20.3 0.0 0.00053 20.0 0.0 1.2 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Beach PF02138.18 EWM27782.1 - 4.8e-97 324.6 0.0 6.5e-97 324.2 0.0 1.1 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 EWM27782.1 - 4.3e-08 33.2 0.0 8e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH B12D PF06522.11 EWM27784.1 - 6.2e-07 29.1 0.0 1.2e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Histone PF00125.24 EWM27785.1 - 2e-40 138.2 0.5 3e-40 137.6 0.5 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EWM27785.1 - 0.0045 17.3 0.1 0.0069 16.7 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EWM27785.1 - 0.025 14.7 0.2 0.044 13.9 0.1 1.4 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold TPR_1 PF00515.28 EWM27786.1 - 0.011 15.6 0.7 0.019 14.8 0.7 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat RRM_1 PF00076.22 EWM27790.1 - 1.2e-08 34.6 0.0 2.3e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 EWM27791.1 - 1.7e-30 104.6 8.0 1.1e-08 35.5 0.1 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat WD40_like PF17005.5 EWM27791.1 - 6e-07 29.1 0.0 0.00038 19.9 0.0 2.7 3 0 0 3 3 3 2 WD40-like domain ANAPC4_WD40 PF12894.7 EWM27791.1 - 0.00017 21.8 0.0 5 7.5 0.0 4.4 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EWM27791.1 - 0.0042 16.1 0.0 0.32 9.9 0.0 2.4 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Oxidored-like PF09791.9 EWM27792.1 - 0.017 14.8 2.1 0.035 13.8 2.1 1.5 1 0 0 1 1 1 0 Oxidoreductase-like protein, N-terminal MFS_1 PF07690.16 EWM27793.1 - 9.9e-15 54.3 53.3 5e-07 29.0 25.7 3.4 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 EWM27793.1 - 5.8e-06 25.1 1.2 5.8e-06 25.1 1.2 2.9 2 1 1 3 3 3 1 MFS/sugar transport protein NEMP PF10225.9 EWM27793.1 - 0.0032 17.2 2.5 0.0059 16.3 2.5 1.3 1 0 0 1 1 1 1 NEMP family PC-Esterase PF13839.6 EWM27794.1 - 0.00031 20.6 0.0 0.034 13.9 0.0 2.8 2 1 0 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Peptidase_S9 PF00326.21 EWM27795.1 - 1.1e-42 145.9 0.0 1.8e-42 145.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S51 PF03575.17 EWM27795.1 - 1.5e-29 103.1 0.0 2.4e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 Peptidase_S15 PF02129.18 EWM27795.1 - 3.2e-09 36.8 0.1 2e-05 24.4 0.1 2.3 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 EWM27795.1 - 1.3e-08 34.4 0.4 0.00044 19.6 0.3 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EWM27795.1 - 8.7e-07 28.8 0.3 0.00059 19.6 0.6 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 EWM27795.1 - 7.9e-06 25.6 0.1 2.7e-05 23.8 0.1 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 EWM27795.1 - 0.00013 22.7 5.0 0.00013 22.7 5.0 3.4 2 2 0 2 2 2 1 Alpha/beta hydrolase family BAAT_C PF08840.11 EWM27795.1 - 0.00045 20.2 0.0 0.0012 18.9 0.0 1.7 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal LIP PF03583.14 EWM27795.1 - 0.0022 17.4 0.5 0.0038 16.6 0.5 1.3 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_3 PF07859.13 EWM27795.1 - 0.0035 17.2 1.9 1.3 8.8 0.0 3.1 4 0 0 4 4 4 2 alpha/beta hydrolase fold Esterase PF00756.20 EWM27795.1 - 0.017 14.8 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative esterase COesterase PF00135.28 EWM27795.1 - 0.044 12.6 0.3 0.072 11.9 0.3 1.2 1 0 0 1 1 1 0 Carboxylesterase family Abhydrolase_4 PF08386.10 EWM27795.1 - 0.13 12.4 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein Aft1_HRA PF11786.8 EWM27796.1 - 0.0022 18.3 1.2 0.0045 17.3 1.2 1.5 1 0 0 1 1 1 1 Aft1 HRA domain Pkinase PF00069.25 EWM27797.1 - 7.9e-43 146.7 0.0 1e-42 146.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM27797.1 - 4e-25 88.6 0.0 1.1e-24 87.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EWM27797.1 - 9.3e-08 31.2 0.0 1.1e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EWM27797.1 - 7.8e-06 25.4 0.1 1.1e-05 24.9 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EWM27797.1 - 0.00074 18.9 0.0 0.00086 18.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EWM27797.1 - 0.019 14.9 0.1 0.029 14.3 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EWM27797.1 - 0.12 11.3 0.1 0.15 11.0 0.1 1.0 1 0 0 1 1 1 0 Haspin like kinase domain Cu-oxidase_3 PF07732.15 EWM27798.1 - 5.4e-05 23.2 0.2 0.016 15.2 0.2 2.5 1 1 0 1 1 1 1 Multicopper oxidase UBA PF00627.31 EWM27799.1 - 6e-22 77.2 8.6 1.1e-10 41.1 0.0 3.2 4 0 0 4 4 4 2 UBA/TS-N domain ubiquitin PF00240.23 EWM27799.1 - 1.7e-13 50.1 0.0 3e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.11 EWM27799.1 - 1.3e-11 44.0 0.0 3.1e-11 42.8 0.0 1.7 2 0 0 2 2 2 1 XPC-binding domain UBA_3 PF09288.10 EWM27799.1 - 0.00026 20.7 0.0 0.42 10.5 0.0 2.5 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain Rad60-SLD_2 PF13881.6 EWM27799.1 - 0.00081 19.5 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.16 EWM27799.1 - 0.0012 18.5 0.4 0.031 14.0 0.1 3.2 3 1 0 3 3 3 1 CUE domain WIYLD PF10440.9 EWM27799.1 - 0.021 14.6 0.1 6.7 6.6 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain DUF1421 PF07223.11 EWM27799.1 - 0.028 14.2 0.2 10 6.1 0.0 2.7 3 0 0 3 3 3 0 UBA-like domain (DUF1421) Rad60-SLD PF11976.8 EWM27799.1 - 0.082 12.7 0.1 0.23 11.3 0.1 1.8 2 1 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like HBS1_N PF08938.10 EWM27799.1 - 0.37 11.1 2.1 39 4.6 3.8 2.6 2 0 0 2 2 2 0 HBS1 N-terminus Transthyretin PF00576.21 EWM27800.1 - 6.3e-39 133.1 0.0 7.9e-39 132.8 0.0 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family ABC2_membrane PF01061.24 EWM27801.1 - 4.4e-40 137.3 7.9 7.1e-40 136.7 7.9 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EWM27801.1 - 7e-23 81.7 0.0 1.4e-22 80.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EWM27801.1 - 4.1e-06 27.3 0.2 9.6e-06 26.1 0.2 1.6 1 0 0 1 1 1 1 AAA ATPase domain ABC2_membrane_3 PF12698.7 EWM27801.1 - 0.00022 20.5 6.3 0.00022 20.5 6.3 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 EWM27801.1 - 0.00036 20.5 0.1 0.00081 19.3 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase Rad17 PF03215.15 EWM27801.1 - 0.00057 19.9 0.0 0.001 19.0 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 EWM27801.1 - 0.0016 18.8 0.0 0.0083 16.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 EWM27801.1 - 0.0044 16.9 0.9 0.31 10.8 0.4 2.2 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EWM27801.1 - 0.02 14.6 0.1 0.048 13.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 EWM27801.1 - 0.026 13.6 0.2 0.048 12.7 0.2 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 EWM27801.1 - 0.044 13.9 0.0 0.35 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EWM27801.1 - 0.044 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 EWM27801.1 - 0.047 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EWM27801.1 - 0.052 14.0 0.1 0.099 13.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 EWM27801.1 - 0.087 12.2 0.0 1.9 7.8 0.0 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 EWM27801.1 - 0.12 12.0 0.1 0.4 10.2 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EWM27801.1 - 0.13 12.5 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EWM27801.1 - 0.16 12.1 0.3 0.4 10.8 0.3 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF4407 PF14362.6 EWM27802.1 - 5.5 6.2 20.0 1.6 8.0 8.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Fer2 PF00111.27 EWM27804.1 - 2.1e-13 50.0 1.3 3.9e-13 49.1 1.3 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain HAD PF12710.7 EWM27806.1 - 0.14 12.5 0.7 0.31 11.4 0.5 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase CYTH PF01928.21 EWM27807.1 - 0.0017 18.3 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 CYTH domain MspA PF09203.11 EWM27807.1 - 0.071 13.0 6.7 0.16 11.8 6.7 1.6 1 0 0 1 1 1 0 MspA Cu-oxidase_2 PF07731.14 EWM27808.1 - 2.1e-07 30.8 0.0 2.4e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Multicopper oxidase ATG_C PF09333.11 EWM27812.1 - 2.3e-07 31.1 0.0 4.2e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Sporozoite_P67 PF05642.11 EWM27812.1 - 0.0026 16.0 3.5 0.0033 15.6 3.5 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen ATP-synt_C PF00137.21 EWM27812.1 - 7.7 7.0 9.5 19 5.7 5.4 2.5 1 1 1 2 2 2 0 ATP synthase subunit C HECT PF00632.25 EWM27813.1 - 1.5e-29 103.4 0.0 1.9e-29 103.1 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HECT PF00632.25 EWM27814.1 - 7.7e-09 35.5 0.0 7.7e-09 35.5 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Zn_peptidase PF04228.13 EWM27816.1 - 0.026 14.0 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase UBM PF14377.6 EWM27817.1 - 1.5e-18 65.5 17.5 1.1e-11 43.8 1.8 4.4 3 1 1 4 4 4 3 Ubiquitin binding region CSTF_C PF14304.6 EWM27817.1 - 4.9 6.8 9.6 31 4.3 0.1 4.5 4 1 1 5 5 5 0 Transcription termination and cleavage factor C-terminal DUF913 PF06025.12 EWM27821.1 - 3e-20 72.6 0.1 3.8e-20 72.2 0.1 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) Flu_NP PF00506.18 EWM27821.1 - 0.1 11.2 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Influenza virus nucleoprotein UbiA PF01040.18 EWM27823.1 - 4.3e-10 39.3 0.4 1.6e-09 37.5 0.4 1.9 1 1 1 2 2 2 1 UbiA prenyltransferase family Mrr_N PF14338.6 EWM27824.1 - 0.097 12.8 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 Mrr N-terminal domain UbiA PF01040.18 EWM27825.1 - 4e-09 36.1 0.5 9.2e-09 35.0 0.3 1.6 1 1 1 2 2 2 1 UbiA prenyltransferase family F-box-like PF12937.7 EWM27826.1 - 0.084 12.8 0.0 1.6 8.7 0.0 2.9 2 1 0 2 2 2 0 F-box-like N1221 PF07923.13 EWM27826.1 - 0.097 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 N1221-like protein F-box-like PF12937.7 EWM27827.1 - 0.084 12.8 0.0 1.6 8.7 0.0 2.9 2 1 0 2 2 2 0 F-box-like N1221 PF07923.13 EWM27827.1 - 0.097 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 N1221-like protein Amidohydro_2 PF04909.14 EWM27828.1 - 3.3e-23 82.9 0.3 4.5e-23 82.5 0.3 1.3 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.14 EWM27829.1 - 3.4e-22 79.6 0.1 4.7e-22 79.1 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase Helicase_C PF00271.31 EWM27830.1 - 7e-27 94.0 0.0 1.2e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.6 EWM27830.1 - 0.041 14.1 0.0 0.18 12.0 0.0 1.9 2 0 0 2 2 2 0 Helicase C-terminal domain MCLC PF05934.11 EWM27830.1 - 0.29 9.8 3.5 0.38 9.4 3.5 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) IHABP4_N PF16174.5 EWM27830.1 - 0.31 11.6 9.9 0.6 10.7 9.9 1.4 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal RNA_pol_Rpc4 PF05132.14 EWM27830.1 - 3.7 8.0 5.4 5.9 7.3 5.4 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 EGF_2 PF07974.13 EWM27831.1 - 0.062 13.7 0.5 0.062 13.7 0.5 2.6 3 0 0 3 3 3 0 EGF-like domain Laminin_EGF PF00053.24 EWM27831.1 - 0.2 11.8 7.4 0.1 12.7 4.3 2.2 2 1 0 2 2 2 0 Laminin EGF domain ABC_membrane PF00664.23 EWM27832.1 - 6.2e-62 209.7 18.5 5.3e-38 131.2 4.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EWM27832.1 - 4.7e-43 147.0 0.0 6.8e-27 94.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 EWM27832.1 - 1.3e-05 25.6 0.1 0.12 12.7 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 EWM27832.1 - 1.5e-05 24.5 0.0 0.17 11.3 0.0 3.9 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EWM27832.1 - 0.00074 19.8 0.6 2.1 8.6 0.1 3.1 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 EWM27832.1 - 0.002 18.7 0.0 1.9 8.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EWM27832.1 - 0.0021 17.8 0.0 0.29 10.9 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EWM27832.1 - 0.0024 17.7 0.3 1.1 9.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EWM27832.1 - 0.0031 17.6 0.1 0.12 12.5 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_25 PF13481.6 EWM27832.1 - 0.0038 16.8 0.1 0.39 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EWM27832.1 - 0.02 14.8 0.0 5.6 6.8 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase T2SSE PF00437.20 EWM27832.1 - 0.069 12.2 0.0 1.1 8.2 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF87 PF01935.17 EWM27832.1 - 0.07 13.2 0.5 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_24 PF13479.6 EWM27832.1 - 0.11 12.2 0.9 11 5.7 0.1 2.8 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 EWM27832.1 - 0.17 12.3 0.5 5.4 7.4 0.1 2.9 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 EWM27832.1 - 0.24 11.3 0.0 1 9.2 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF5345 PF17280.2 EWM27832.1 - 0.25 11.4 1.1 5.4 7.1 0.1 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5345) ABC_membrane PF00664.23 EWM27833.1 - 4e-62 210.3 18.6 4.3e-38 131.5 4.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EWM27833.1 - 6.8e-29 101.1 0.0 3.3e-13 50.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 EWM27833.1 - 3.4e-05 24.3 0.3 0.099 13.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 EWM27833.1 - 0.0015 19.1 0.0 1.6 9.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EWM27833.1 - 0.0016 18.2 0.0 0.24 11.1 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EWM27833.1 - 0.0023 18.0 0.1 0.1 12.7 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_25 PF13481.6 EWM27833.1 - 0.0035 16.9 0.1 0.33 10.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EWM27833.1 - 0.0081 16.4 0.3 3.8 7.8 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EWM27833.1 - 0.0095 15.8 0.1 1 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EWM27833.1 - 0.016 15.1 0.0 4.8 7.0 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase SMC_N PF02463.19 EWM27833.1 - 0.046 13.1 0.0 23 4.4 0.0 2.9 2 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 EWM27833.1 - 0.053 12.6 0.0 0.94 8.5 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF87 PF01935.17 EWM27833.1 - 0.056 13.5 0.5 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain DUF5345 PF17280.2 EWM27833.1 - 0.17 11.9 1.1 4.6 7.3 0.1 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5345) ATPase_2 PF01637.18 EWM27833.1 - 0.2 11.5 0.0 0.87 9.4 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EWM27833.1 - 0.51 10.0 2.8 9.1 5.9 0.1 2.6 3 0 0 3 3 3 0 AAA domain ECH_1 PF00378.20 EWM27835.1 - 4.9e-69 232.4 0.0 6.4e-69 232.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EWM27835.1 - 4.2e-18 65.9 0.0 6.6e-18 65.3 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase SDH_sah PF01972.16 EWM27835.1 - 0.012 14.6 0.0 0.028 13.4 0.0 1.6 2 0 0 2 2 2 0 Serine dehydrogenase proteinase IFT46_B_C PF12317.8 EWM27836.1 - 1.2e-28 100.3 0.1 1.8e-28 99.7 0.1 1.2 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal NAD_binding_1 PF00175.21 EWM27838.1 - 9.1e-11 42.4 0.3 4e-09 37.1 0.3 2.9 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EWM27838.1 - 0.00015 21.9 0.0 0.14 12.3 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain XPG_N PF00752.17 EWM27839.1 - 2.2e-30 105.1 0.0 3.9e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EWM27839.1 - 1.2e-29 102.5 0.8 1.7e-29 102.0 0.0 1.7 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 EWM27839.1 - 2.7e-07 31.1 1.3 9.5e-07 29.3 0.0 2.4 2 1 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold 5_3_exonuc_N PF02739.16 EWM27839.1 - 0.00048 20.1 0.0 0.0038 17.1 0.0 2.0 1 1 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain eIF3_subunit PF08597.10 EWM27839.1 - 0.014 15.3 2.7 0.014 15.3 2.7 1.7 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit XRN_N PF03159.18 EWM27839.1 - 0.017 14.6 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus BT1 PF03092.16 EWM27840.1 - 1.8e-43 148.6 17.6 6.2e-32 110.5 4.8 2.9 1 1 1 3 3 3 3 BT1 family BT1 PF03092.16 EWM27841.1 - 3.9e-14 51.8 9.4 9e-12 44.0 2.0 3.0 2 1 1 3 3 3 3 BT1 family Ank_2 PF12796.7 EWM27842.1 - 3.5e-15 56.4 0.0 1.3e-08 35.3 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EWM27842.1 - 8.8e-12 45.0 0.6 0.16 12.3 0.0 5.5 5 1 0 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EWM27842.1 - 2.8e-11 42.6 3.1 0.0058 17.0 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 EWM27842.1 - 4.8e-11 43.0 0.8 2.6e-05 24.7 0.1 4.1 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EWM27842.1 - 1.2e-09 38.2 3.4 0.0052 17.2 0.1 5.8 6 0 0 6 6 6 3 Ankyrin repeat Glycos_transf_2 PF00535.26 EWM27846.1 - 1.4e-11 44.5 0.0 1.9e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EWM27846.1 - 0.00037 20.5 0.0 0.0005 20.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Fringe PF02434.16 EWM27846.1 - 0.0055 16.2 0.0 0.0074 15.7 0.0 1.2 1 0 0 1 1 1 1 Fringe-like Glyco_tranf_2_2 PF10111.9 EWM27846.1 - 0.073 12.5 0.0 0.13 11.7 0.0 1.5 1 1 1 2 2 2 0 Glycosyltransferase like family 2 Rhamno_transf PF11316.8 EWM27846.1 - 0.18 11.1 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Putative rhamnosyl transferase zf-C3HC4_3 PF13920.6 EWM27847.1 - 4.4e-06 26.5 13.8 5.7e-06 26.1 13.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ADD_DNMT3 PF17980.1 EWM27847.1 - 0.11 12.5 0.2 0.11 12.5 0.2 2.2 1 1 1 2 2 2 0 Cysteine rich ADD domain in DNMT3 Defb50 PF17546.2 EWM27847.1 - 0.19 11.7 4.5 0.07 13.1 2.3 1.4 2 0 0 2 2 2 0 Beta defensin 50 Fuseless PF15993.5 EWM27848.1 - 7.2e-21 74.7 14.4 1.3e-14 54.1 9.7 2.9 2 1 0 2 2 2 2 Fuseless Bcl-2_BAD PF10514.9 EWM27848.1 - 0.022 15.3 3.1 1.2 9.6 0.7 2.4 2 0 0 2 2 2 0 Pro-apoptotic Bcl-2 protein, BAD Retrotran_gag_2 PF14223.6 EWM27849.1 - 4.4e-05 23.2 0.2 6.6e-05 22.6 0.2 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF1759 PF03564.15 EWM27849.1 - 0.0085 16.0 0.2 0.012 15.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) YchF-GTPase_C PF06071.13 EWM27850.1 - 1.1e-40 137.7 0.0 2.2e-40 136.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EWM27850.1 - 7e-23 80.9 0.0 1.4e-22 79.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EWM27850.1 - 1e-07 31.6 0.1 2.8e-07 30.2 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 EWM27850.1 - 0.14 12.7 0.1 0.39 11.2 0.1 1.7 1 0 0 1 1 1 0 ABC transporter MnmE_helical PF12631.7 EWM27850.1 - 0.15 12.2 0.1 0.23 11.6 0.1 1.3 1 0 0 1 1 1 0 MnmE helical domain zf-CCHC PF00098.23 EWM27851.1 - 0.00092 19.2 4.5 0.00092 19.2 4.5 2.8 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 EWM27851.1 - 0.14 12.1 11.9 0.069 13.1 3.0 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.6 EWM27851.1 - 0.9 9.3 12.6 1.1 9.1 2.1 2.7 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 EWM27851.1 - 3.6 7.4 7.2 2 8.2 0.4 3.0 4 0 0 4 4 4 0 Zinc knuckle DUF179 PF02622.15 EWM27853.1 - 3e-14 53.3 0.0 5.1e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 Methyltransf_25 PF13649.6 EWM27854.1 - 1.5e-20 73.7 0.0 9.3e-12 45.5 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EWM27854.1 - 2.7e-17 63.2 0.0 8e-12 45.7 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 EWM27854.1 - 8.4e-12 45.1 0.0 1.7e-06 27.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_PK PF05891.12 EWM27854.1 - 3.3e-07 30.1 0.0 6.3e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.6 EWM27854.1 - 4.5e-05 23.3 0.0 0.09 12.6 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain NodS PF05401.11 EWM27854.1 - 0.0007 19.3 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.20 EWM27854.1 - 0.0045 16.1 0.0 0.0078 15.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.14 EWM27854.1 - 0.016 14.8 0.0 0.57 9.7 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase small domain TehB PF03848.14 EWM27854.1 - 0.059 12.8 0.0 3.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Tellurite resistance protein TehB 4HBT PF03061.22 EWM27855.1 - 1.1e-12 48.2 0.0 2.2e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 EWM27855.1 - 0.005 17.3 0.0 0.0086 16.6 0.0 1.6 1 1 0 1 1 1 1 Thioesterase-like superfamily CAP59_mtransfer PF11735.8 EWM27856.1 - 4.1e-54 183.8 0.0 3e-32 112.2 0.0 2.3 2 0 0 2 2 2 2 Cryptococcal mannosyltransferase 1 RSN1_7TM PF02714.15 EWM27857.1 - 2.8e-58 197.4 17.7 2.8e-58 197.4 17.7 2.1 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EWM27857.1 - 1.8e-31 109.0 1.9 2.4e-27 95.6 0.1 3.6 3 0 0 3 3 3 2 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EWM27857.1 - 4.7e-09 36.7 0.0 6.8e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Anoctamin PF04547.12 EWM27857.1 - 0.0055 15.6 5.5 0.012 14.5 5.5 1.5 1 1 0 1 1 1 1 Calcium-activated chloride channel DUF3267 PF11667.8 EWM27857.1 - 0.28 11.5 0.1 0.28 11.5 0.1 3.7 4 1 0 5 5 5 0 Putative zincin peptidase MFS_1 PF07690.16 EWM27858.1 - 1e-38 133.2 31.6 1.5e-24 86.6 17.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EWM27858.1 - 1.5e-12 47.2 2.5 1.5e-12 47.2 2.5 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 EWM27858.1 - 6.7e-12 45.0 8.2 2.5e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 MFS_1 like family MFS_2 PF13347.6 EWM27858.1 - 6.8e-10 38.1 7.7 7.1e-06 24.8 0.4 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_4 PF06779.14 EWM27858.1 - 0.00055 19.4 19.1 0.0057 16.0 19.1 2.1 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB PA PF02225.22 EWM27859.1 - 2.3e-06 27.5 0.0 3.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 PA domain SRP19 PF01922.17 EWM27860.1 - 3.1e-26 92.2 0.0 6e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 SRP19 protein K_channel_TID PF07941.11 EWM27860.1 - 0.016 15.6 15.3 0.26 11.8 10.5 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain TPR_8 PF13181.6 EWM27861.1 - 3.4e-11 42.4 11.3 0.00092 19.2 0.1 9.9 12 0 0 12 12 9 1 Tetratricopeptide repeat TPR_2 PF07719.17 EWM27861.1 - 1.3e-10 40.6 18.1 7.3e-05 22.6 0.2 10.0 11 0 0 11 11 10 2 Tetratricopeptide repeat Suf PF05843.14 EWM27861.1 - 6.5e-10 39.5 14.8 0.0054 16.8 4.3 5.6 4 2 0 4 4 4 3 Suppressor of forked protein (Suf) TPR_14 PF13428.6 EWM27861.1 - 1.7e-09 37.7 32.0 0.0026 18.4 0.0 12.8 10 3 5 15 15 12 1 Tetratricopeptide repeat TPR_15 PF13429.6 EWM27861.1 - 2.7e-09 36.7 21.9 0.00059 19.1 0.2 6.9 6 2 1 7 7 7 3 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EWM27861.1 - 4.9e-09 36.2 17.1 0.011 15.8 0.0 7.8 6 2 1 8 8 8 3 Mad3/BUB1 homology region 1 TPR_1 PF00515.28 EWM27861.1 - 3.1e-06 26.8 11.5 0.0092 15.8 0.2 7.7 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_7 PF13176.6 EWM27861.1 - 1.9e-05 24.4 7.4 0.011 15.8 0.1 6.7 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 EWM27861.1 - 2.2e-05 24.9 9.8 5.5 7.6 0.0 7.6 8 0 0 8 8 7 2 Tetratricopeptide repeat HAT PF02184.16 EWM27861.1 - 3.8e-05 23.5 3.9 5.5 7.0 0.1 5.8 4 0 0 4 4 4 1 HAT (Half-A-TPR) repeat NRDE-2 PF08424.10 EWM27861.1 - 4.9e-05 22.6 10.2 0.0025 17.0 1.9 5.0 3 2 2 5 5 5 1 NRDE-2, necessary for RNA interference TPR_12 PF13424.6 EWM27861.1 - 0.00069 19.9 11.3 0.024 14.9 0.0 5.6 5 1 0 5 5 4 1 Tetratricopeptide repeat RPN7 PF10602.9 EWM27861.1 - 0.001 18.8 0.7 1.8 8.2 0.2 3.1 2 1 0 2 2 2 2 26S proteasome subunit RPN7 TPR_16 PF13432.6 EWM27861.1 - 0.031 14.9 0.0 0.031 14.9 0.0 6.4 7 0 0 7 7 6 0 Tetratricopeptide repeat DALR_1 PF05746.15 EWM27861.1 - 0.076 13.2 0.1 0.57 10.4 0.1 2.7 1 1 0 1 1 1 0 DALR anticodon binding domain TPR_17 PF13431.6 EWM27861.1 - 0.1 13.0 12.9 4.6 7.8 0.0 6.8 8 1 0 8 8 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 EWM27861.1 - 0.13 11.9 5.4 1.7 8.4 0.2 4.8 5 0 0 5 5 5 0 TPR repeat TPR_4 PF07721.14 EWM27861.1 - 1.5 9.6 0.0 1.5 9.6 0.0 4.3 5 0 0 5 5 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EWM27861.1 - 2.9 8.7 20.7 4.9 8.0 0.2 7.9 10 1 0 10 10 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EWM27861.1 - 7.3 6.6 15.5 0.22 11.5 0.1 5.4 5 0 0 5 5 4 0 Tetratricopeptide repeat Nrap_D3 PF17404.2 EWM27863.1 - 8.6e-36 123.4 0.0 1.3e-35 122.8 0.0 1.3 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D4 PF17405.2 EWM27863.1 - 2.9e-29 102.0 0.1 5.2e-29 101.1 0.1 1.3 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 EWM27863.1 - 3.2e-22 79.0 0.0 5.2e-19 68.6 0.0 3.4 2 1 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap PF03813.14 EWM27863.1 - 2.5e-19 69.8 0.0 2.3e-18 66.7 0.0 2.1 1 1 0 1 1 1 1 Nrap protein domain 1 Nrap_D2 PF17403.2 EWM27863.1 - 8.4e-18 64.6 0.0 2.7e-16 59.7 0.0 2.3 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap_D6 PF17407.2 EWM27863.1 - 1.4e-12 47.9 0.0 2.4e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 6 CRCB PF02537.15 EWM27866.1 - 3.5e-28 97.7 9.0 4.7e-17 62.1 0.6 2.2 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) Spore_permease PF03845.13 EWM27866.1 - 1 8.1 5.0 0.67 8.7 2.1 1.9 2 0 0 2 2 2 0 Spore germination protein DUF1180 PF06679.12 EWM27866.1 - 2.2 8.7 0.0 2.2 8.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) Sua5_yciO_yrdC PF01300.18 EWM27868.1 - 7.6e-45 152.6 0.7 2.9e-43 147.5 0.0 2.9 2 1 0 2 2 2 1 Telomere recombination SUA5 PF03481.13 EWM27868.1 - 1e-09 39.0 0.0 2.4e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Hydrolase_3 PF08282.12 EWM27870.1 - 2.8e-50 171.4 0.0 9.8e-29 100.8 0.0 2.0 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EWM27870.1 - 1.5e-11 44.4 0.0 1.6e-09 37.7 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 EWM27870.1 - 9.1e-07 29.4 0.0 0.00015 22.1 0.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 EWM27870.1 - 0.0072 15.5 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase HAD PF12710.7 EWM27870.1 - 0.053 13.9 0.2 4.5 7.6 0.0 2.9 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EWM27870.1 - 0.2 11.8 0.0 0.93 9.6 0.0 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EWM27870.1 - 0.26 11.4 0.0 0.83 9.7 0.0 1.7 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF2870 PF11069.8 EWM27871.1 - 5.2e-32 110.1 0.0 1.1e-31 109.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) ABC_membrane PF00664.23 EWM27872.1 - 9.5e-63 212.4 24.7 1.2e-33 116.9 7.1 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 EWM27872.1 - 5.1e-52 176.0 0.0 3.4e-29 102.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EWM27872.1 - 3.1e-08 33.3 3.2 0.036 13.5 0.3 4.1 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EWM27872.1 - 7.4e-06 25.6 1.4 0.11 12.3 0.3 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EWM27872.1 - 1.3e-05 25.3 0.2 0.013 15.6 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 EWM27872.1 - 8.4e-05 23.2 3.5 0.22 12.0 0.1 3.1 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EWM27872.1 - 0.00016 22.1 2.3 0.06 13.7 0.4 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EWM27872.1 - 0.00017 21.5 0.4 0.41 10.5 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 EWM27872.1 - 0.00034 20.5 7.0 0.12 12.1 0.2 3.6 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EWM27872.1 - 0.00081 19.0 1.6 0.058 13.0 0.1 2.8 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 EWM27872.1 - 0.006 16.9 2.4 1.3 9.3 0.1 3.1 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.17 EWM27872.1 - 0.0073 16.4 2.2 0.48 10.5 0.0 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_30 PF13604.6 EWM27872.1 - 0.0092 15.7 0.4 0.4 10.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 EWM27872.1 - 0.012 15.6 0.1 0.07 13.0 0.0 2.3 2 1 0 2 2 2 0 NTPase Dynamin_N PF00350.23 EWM27872.1 - 0.015 15.3 0.8 5.1 7.1 0.1 3.0 3 0 0 3 3 3 0 Dynamin family FtsK_SpoIIIE PF01580.18 EWM27872.1 - 0.023 14.1 0.4 5.4 6.3 0.1 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 EWM27872.1 - 0.046 13.0 0.8 5 6.3 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin SbcCD_C PF13558.6 EWM27872.1 - 0.071 13.4 0.0 17 5.7 0.0 3.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit T2SSE PF00437.20 EWM27872.1 - 0.13 11.3 0.3 18 4.3 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 EWM27872.1 - 0.28 10.1 3.4 1.4 7.8 0.1 2.5 2 1 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Adeno_IVa2 PF02456.15 EWM27872.1 - 0.35 9.6 0.9 7 5.3 0.1 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein PMSR PF01625.21 EWM27874.1 - 1.2e-56 191.1 0.1 1.6e-56 190.7 0.1 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Abhydrolase_6 PF12697.7 EWM27875.1 - 1.9e-06 28.6 0.4 3e-06 28.0 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 EWM27875.1 - 3.8e-06 26.0 0.0 0.0014 17.6 0.0 3.0 3 0 0 3 3 3 1 Chlorophyllase enzyme Ser_hydrolase PF06821.13 EWM27875.1 - 0.0006 19.7 0.0 0.001 19.0 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase Thioesterase PF00975.20 EWM27875.1 - 0.0058 16.8 0.0 0.009 16.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain ETF PF01012.21 EWM27875.1 - 0.022 14.6 0.1 0.037 13.9 0.1 1.2 1 0 0 1 1 1 0 Electron transfer flavoprotein domain Abhydrolase_3 PF07859.13 EWM27875.1 - 0.05 13.5 0.0 0.079 12.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Transketolase_C PF02780.20 EWM27875.1 - 0.058 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Transketolase, C-terminal domain Abhydrolase_1 PF00561.20 EWM27875.1 - 0.09 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EWM27875.1 - 0.14 11.4 0.0 0.38 10.0 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF3530 PF12048.8 EWM27875.1 - 0.18 11.2 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) LIDHydrolase PF10230.9 EWM27875.1 - 0.2 11.2 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF900 PF05990.12 EWM27875.1 - 0.22 11.0 0.0 0.37 10.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Ank_4 PF13637.6 EWM27876.1 - 7.2e-14 52.0 0.1 5.6e-07 30.0 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EWM27876.1 - 4.6e-13 49.6 0.0 1.4e-12 48.0 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EWM27876.1 - 1.5e-09 37.3 0.0 0.001 19.4 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EWM27876.1 - 1.2e-08 35.0 0.0 2.8e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EWM27876.1 - 3.6e-08 33.5 0.0 0.0003 21.1 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat zf-RING_2 PF13639.6 EWM27877.1 - 2.9e-11 43.5 5.5 1.1e-10 41.7 5.5 2.1 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EWM27877.1 - 1.6e-08 34.7 3.7 1.6e-08 34.7 3.7 2.7 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EWM27877.1 - 4e-06 26.6 4.5 4e-06 26.6 4.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EWM27877.1 - 9.4e-05 22.1 3.1 9.4e-05 22.1 3.1 2.1 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 EWM27877.1 - 0.00018 21.3 4.7 0.00018 21.3 4.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Atx10homo_assoc PF09759.9 EWM27877.1 - 0.00033 20.6 0.3 0.031 14.3 0.0 3.4 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain zf-RING_5 PF14634.6 EWM27877.1 - 0.0011 18.8 3.4 0.0031 17.4 3.4 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EWM27877.1 - 0.0022 18.0 0.9 0.01 15.8 0.9 2.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EWM27877.1 - 0.0023 17.8 2.2 0.0048 16.7 2.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EWM27877.1 - 0.0053 16.8 1.6 0.016 15.2 1.6 1.9 1 0 0 1 1 1 1 RING-type zinc-finger TIP120 PF08623.10 EWM27877.1 - 0.036 13.9 0.1 13 5.6 0.0 3.1 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) RINGv PF12906.7 EWM27877.1 - 0.11 12.7 5.4 0.25 11.5 5.4 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 EWM27877.1 - 0.58 10.0 5.5 0.22 11.4 2.5 1.9 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain EMC1_C PF07774.13 EWM27878.1 - 4.6e-56 189.9 0.0 6.5e-56 189.4 0.0 1.2 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 EWM27878.1 - 2.7e-06 27.1 0.5 0.3 10.6 0.0 3.5 2 1 1 3 3 3 3 PQQ-like domain Peptidase_M20 PF01546.28 EWM27879.1 - 2.3e-25 89.5 0.0 3.2e-24 85.8 0.0 2.5 2 2 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.32 EWM27879.1 - 1.6e-14 54.0 5.6 2.3e-05 25.1 0.2 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat M20_dimer PF07687.14 EWM27879.1 - 2.2e-10 40.4 0.0 5.9e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EWM27879.1 - 0.077 12.7 0.0 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 Peptidase family M28 SLIDE PF09111.10 EWM27880.1 - 1.3e-37 128.3 1.2 4.7e-37 126.5 1.2 2.0 1 0 0 1 1 1 1 SLIDE HAND PF09110.11 EWM27880.1 - 5.8e-11 43.1 0.1 5.8e-11 43.1 0.1 3.1 3 0 0 3 3 3 1 HAND Myb_DNA-bind_6 PF13921.6 EWM27880.1 - 0.00011 22.3 0.7 0.0005 20.3 0.7 2.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EWM27880.1 - 0.0055 16.9 1.8 0.014 15.6 0.3 2.5 3 0 0 3 3 3 1 Myb-like DNA-binding domain TetR_C_11 PF16859.5 EWM27880.1 - 3.6 7.9 7.6 0.2 12.0 1.1 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Esterase_phd PF10503.9 EWM27881.1 - 1.2e-12 47.9 0.1 1.7e-12 47.3 0.1 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 EWM27881.1 - 3.2e-06 26.8 0.0 8.8e-06 25.3 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 EWM27881.1 - 0.0064 15.4 0.0 0.01 14.7 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_3 PF07859.13 EWM27881.1 - 0.0081 16.0 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold LapA_dom PF06305.11 EWM27881.1 - 0.022 14.6 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Abhydrolase_1 PF00561.20 EWM27881.1 - 0.023 14.4 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 EWM27881.1 - 0.028 14.1 0.0 0.046 13.4 0.0 1.4 1 1 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.8 EWM27881.1 - 0.06 12.6 0.2 0.11 11.8 0.2 1.4 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EWM27881.1 - 0.071 12.9 0.1 0.18 11.5 0.1 1.6 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EWM27881.1 - 0.076 13.6 5.6 0.024 15.3 2.4 1.8 2 1 0 2 2 2 0 Alpha/beta hydrolase family AXE1 PF05448.12 EWM27881.1 - 0.15 10.7 0.0 0.4 9.3 0.0 1.6 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Sugar_tr PF00083.24 EWM27882.1 - 2.4e-99 333.3 24.8 2.8e-99 333.0 24.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EWM27882.1 - 4e-28 98.4 32.3 4e-28 98.4 32.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily L51_S25_CI-B8 PF05047.16 EWM27883.1 - 1.5e-07 31.3 0.0 2.3e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF5536 PF17688.1 EWM27883.1 - 0.15 12.0 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5536) GATase_4 PF13230.6 EWM27884.1 - 1.8e-11 43.4 0.0 3.7e-10 39.2 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 EWM27884.1 - 7.1e-11 42.4 0.0 1.4e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain WD40 PF00400.32 EWM27884.1 - 0.00035 21.3 0.3 0.0096 16.8 0.0 2.9 2 0 0 2 2 2 1 WD domain, G-beta repeat PQQ_3 PF13570.6 EWM27884.1 - 0.0014 19.0 1.5 5.9 7.5 0.0 3.9 3 0 0 3 3 3 2 PQQ-like domain Nup160 PF11715.8 EWM27884.1 - 0.33 9.6 0.1 9.1 4.8 0.0 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 SRP_TPR_like PF17004.5 EWM27885.1 - 6.9e-11 42.2 0.1 1.7e-09 37.7 0.0 2.7 3 0 0 3 3 3 1 Putative TPR-like repeat TPR_19 PF14559.6 EWM27885.1 - 9.8e-11 42.0 27.2 0.052 14.1 0.0 7.6 5 2 3 8 8 8 5 Tetratricopeptide repeat ANAPC3 PF12895.7 EWM27885.1 - 1.4e-09 38.0 0.3 0.00086 19.5 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EWM27885.1 - 1.3e-05 24.9 22.6 0.0057 16.7 0.0 8.6 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_8 PF13181.6 EWM27885.1 - 1.8e-05 24.5 4.5 0.12 12.7 0.0 6.1 7 0 0 7 7 5 1 Tetratricopeptide repeat PPR PF01535.20 EWM27885.1 - 3.3e-05 23.8 0.3 0.49 10.8 0.0 5.1 5 0 0 5 5 5 1 PPR repeat TPR_1 PF00515.28 EWM27885.1 - 9.9e-05 22.0 3.7 0.038 13.8 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat SRP72 PF08492.12 EWM27885.1 - 0.00027 21.3 6.9 0.0007 20.0 6.9 1.6 1 0 0 1 1 1 1 SRP72 RNA-binding domain TPR_11 PF13414.6 EWM27885.1 - 0.00096 18.8 3.7 0.13 12.0 0.0 4.8 5 0 0 5 5 5 1 TPR repeat TPR_12 PF13424.6 EWM27885.1 - 0.0019 18.4 32.0 0.017 15.4 0.1 8.0 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 EWM27885.1 - 0.0065 17.2 45.1 0.18 12.7 0.0 10.7 9 2 2 11 11 11 1 Tetratricopeptide repeat TPR_16 PF13432.6 EWM27885.1 - 0.017 15.8 60.8 0.024 15.3 1.5 8.7 4 3 4 9 9 8 0 Tetratricopeptide repeat TPR_10 PF13374.6 EWM27885.1 - 0.017 14.9 14.0 0.24 11.3 0.1 6.4 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 EWM27885.1 - 0.047 13.8 21.5 0.13 12.4 1.4 6.5 5 1 1 6 6 6 0 Tetratricopeptide repeat PPR_1 PF12854.7 EWM27885.1 - 0.055 13.2 0.2 4 7.2 0.0 3.4 3 0 0 3 3 3 0 PPR repeat DUF4810 PF16068.5 EWM27885.1 - 0.16 12.5 0.2 37 5.0 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4810) TPR_4 PF07721.14 EWM27885.1 - 0.21 12.3 44.9 3.8 8.4 0.6 9.2 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 EWM27885.1 - 2 9.2 0.0 2 9.2 0.0 7.3 9 0 0 9 9 6 0 Tetratricopeptide repeat TPR_20 PF14561.6 EWM27885.1 - 9.9 6.6 18.0 12 6.3 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat SNF2_N PF00176.23 EWM27886.1 - 4.5e-47 160.5 0.0 5.6e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EWM27886.1 - 7.3e-07 29.5 0.0 2.2e-06 28.0 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SWI2_SNF2 PF18766.1 EWM27886.1 - 6.5e-05 22.7 0.0 9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 SWI2/SNF2 ATPase ResIII PF04851.15 EWM27886.1 - 0.00012 22.1 0.0 0.0002 21.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EWM27886.1 - 0.0091 15.2 0.0 0.076 12.2 0.0 2.2 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_14 PF13173.6 EWM27886.1 - 0.0095 16.0 0.0 0.026 14.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 EWM27886.1 - 0.013 15.3 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase DEAD_2 PF06733.15 EWM27886.1 - 0.018 14.6 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 DEAD_2 DUF4604 PF15377.6 EWM27890.1 - 2 8.8 8.2 0.61 10.5 5.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Peptidase_C1 PF00112.23 EWM27891.1 - 9.6e-52 176.2 0.1 1.7e-51 175.4 0.1 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EWM27891.1 - 6.9e-10 39.2 0.2 1.3e-09 38.4 0.2 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EWM27891.1 - 0.0015 17.4 0.3 0.0023 16.8 0.3 1.1 1 0 0 1 1 1 1 Peptidase C1-like family DUF809 PF05663.11 EWM27892.1 - 1.2 9.2 3.9 1.9 8.7 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF809) HHV6-IE PF03753.13 EWM27893.1 - 0.021 12.3 0.8 0.025 12.1 0.8 1.0 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein Sporozoite_P67 PF05642.11 EWM27893.1 - 0.19 9.8 9.3 0.23 9.5 9.3 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Apt1 PF10351.9 EWM27893.1 - 0.99 8.2 5.3 1.1 8.0 5.3 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain EamA PF00892.20 EWM27894.1 - 1.8e-19 70.2 15.0 1.6e-09 38.1 7.9 2.9 2 1 0 2 2 2 2 EamA-like transporter family CAF1-p150_C2 PF15539.6 EWM27894.1 - 0.017 14.6 0.2 0.028 13.9 0.2 1.2 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term PK PF00224.21 EWM27895.1 - 2.5e-144 480.5 1.2 7.5e-144 478.9 1.2 1.7 2 0 0 2 2 2 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EWM27895.1 - 9.8e-26 90.3 0.5 2.1e-25 89.2 0.5 1.6 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain Suc_Fer-like PF06999.12 EWM27895.1 - 2.8e-24 86.1 0.0 9.6e-24 84.3 0.0 1.9 2 0 0 2 2 2 1 Sucrase/ferredoxin-like HpcH_HpaI PF03328.14 EWM27895.1 - 0.0028 16.8 0.0 0.0053 15.9 0.0 1.5 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DUF872 PF05915.12 EWM27896.1 - 1.5e-12 47.7 0.0 1.6e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) DUF3040 PF11239.8 EWM27896.1 - 0.033 14.5 0.7 0.25 11.7 0.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) Sdh_cyt PF01127.22 EWM27896.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.4 1 1 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Gram_pos_anchor PF00746.21 EWM27896.1 - 6.8 6.7 6.1 8.2 6.5 0.5 2.2 2 0 0 2 2 2 0 LPXTG cell wall anchor motif SOBP PF15279.6 EWM27898.1 - 1.2 9.7 4.0 1.7 9.1 4.0 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein AAA_23 PF13476.6 EWM27899.1 - 0.076 13.5 5.3 0.079 13.5 5.3 1.2 1 0 0 1 1 1 0 AAA domain Ilar_coat PF01787.16 EWM27899.1 - 0.16 11.8 2.2 0.11 12.2 0.7 1.4 1 1 0 1 1 1 0 Ilarvirus coat protein DUF4407 PF14362.6 EWM27899.1 - 0.37 10.1 8.1 0.46 9.8 8.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RR_TM4-6 PF06459.12 EWM27899.1 - 8 6.2 14.0 9 6.0 14.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RRM_1 PF00076.22 EWM27900.1 - 1.1e-44 150.1 0.0 1.3e-15 57.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EWM27900.1 - 0.00016 21.6 0.0 0.0028 17.7 0.0 2.3 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.6 EWM27900.1 - 0.00079 19.4 0.1 0.0048 16.9 0.0 2.1 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EWM27900.1 - 0.0012 18.9 0.1 0.14 12.3 0.0 3.0 3 0 0 3 3 3 1 RNA recognition motif Limkain-b1 PF11608.8 EWM27900.1 - 0.04 14.0 0.0 3 8.0 0.0 2.6 2 0 0 2 2 2 0 Limkain b1 VIT1 PF01988.19 EWM27901.1 - 0.00078 19.4 0.4 0.0012 18.7 0.4 1.3 1 0 0 1 1 1 1 VIT family Na_H_Exchanger PF00999.21 EWM27902.1 - 7.1e-53 179.8 45.4 9.2e-53 179.4 45.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family MIF4G PF02854.19 EWM27903.1 - 1.2e-32 113.3 0.1 6.6e-16 58.6 0.0 2.6 3 0 0 3 3 2 2 MIF4G domain Upf2 PF04050.14 EWM27903.1 - 2.8e-15 57.2 17.3 1.1e-14 55.4 12.8 2.4 1 1 1 2 2 1 1 Up-frameshift suppressor 2 RXT2_N PF08595.11 EWM27903.1 - 0.016 15.2 6.0 0.034 14.2 6.0 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Nop14 PF04147.12 EWM27903.1 - 0.02 13.2 17.3 0.042 12.1 17.3 1.5 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EWM27903.1 - 0.19 10.0 8.4 0.27 9.5 8.4 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4471 PF14740.6 EWM27903.1 - 0.53 9.5 2.9 0.92 8.7 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) FmiP_Thoc5 PF09766.9 EWM27903.1 - 0.72 9.1 6.3 1.3 8.2 6.3 1.3 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 Myc_N PF01056.18 EWM27903.1 - 1.2 8.9 17.2 2.5 7.9 17.2 1.5 1 0 0 1 1 1 0 Myc amino-terminal region TRAP_alpha PF03896.16 EWM27903.1 - 1.4 8.0 10.5 2.4 7.3 10.5 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Eapp_C PF10238.9 EWM27903.1 - 1.5 8.9 4.9 2.9 8.0 4.9 1.4 1 0 0 1 1 1 0 E2F-associated phosphoprotein F-protein PF00469.20 EWM27903.1 - 1.9 8.0 7.3 3.6 7.1 7.3 1.4 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef NOA36 PF06524.12 EWM27903.1 - 4 6.7 13.8 6.4 6.0 13.8 1.2 1 0 0 1 1 1 0 NOA36 protein FancD2 PF14631.6 EWM27903.1 - 4 4.7 5.8 5.6 4.2 5.8 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease RR_TM4-6 PF06459.12 EWM27903.1 - 4.5 7.0 12.7 8 6.2 12.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4746 PF15928.5 EWM27903.1 - 5.2 6.4 16.6 10 5.5 16.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Dsh_C PF12316.8 EWM27903.1 - 5.2 7.4 6.8 12 6.2 6.8 1.6 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF913 PF06025.12 EWM27903.1 - 5.6 5.8 7.6 9.2 5.1 7.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) GOLD_2 PF13897.6 EWM27903.1 - 7.9 7.0 13.0 16 6.0 13.0 1.4 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking NPR3 PF03666.13 EWM27903.1 - 8 5.1 6.4 12 4.5 6.4 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MIF4G PF02854.19 EWM27904.1 - 1.6e-16 60.6 0.0 4.3e-16 59.2 0.0 1.7 2 1 0 2 2 1 1 MIF4G domain Upf2 PF04050.14 EWM27904.1 - 2.1e-15 57.6 17.7 1.5e-14 54.9 13.7 2.4 1 1 1 2 2 1 1 Up-frameshift suppressor 2 RXT2_N PF08595.11 EWM27904.1 - 0.012 15.6 6.0 0.025 14.6 6.0 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Nop14 PF04147.12 EWM27904.1 - 0.02 13.1 17.8 0.044 12.0 17.8 1.5 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EWM27904.1 - 0.13 10.6 8.3 0.17 10.2 8.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4471 PF14740.6 EWM27904.1 - 0.41 9.8 3.0 0.71 9.0 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) Myc_N PF01056.18 EWM27904.1 - 0.53 10.1 16.5 1.1 9.1 16.5 1.5 1 0 0 1 1 1 0 Myc amino-terminal region FmiP_Thoc5 PF09766.9 EWM27904.1 - 0.55 9.5 6.3 1 8.6 6.3 1.3 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 TRAP_alpha PF03896.16 EWM27904.1 - 0.88 8.7 10.3 1.6 7.9 10.3 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Eapp_C PF10238.9 EWM27904.1 - 1.1 9.3 5.0 2.2 8.4 5.0 1.4 1 0 0 1 1 1 0 E2F-associated phosphoprotein F-protein PF00469.20 EWM27904.1 - 1.4 8.5 7.3 2.8 7.5 7.3 1.4 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef NOA36 PF06524.12 EWM27904.1 - 2 7.7 13.1 3.1 7.0 13.1 1.2 1 0 0 1 1 1 0 NOA36 protein Zip PF02535.22 EWM27904.1 - 2.4 7.3 3.6 3.5 6.7 3.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4746 PF15928.5 EWM27904.1 - 2.9 7.2 16.2 5.8 6.3 16.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) FancD2 PF14631.6 EWM27904.1 - 3 5.1 5.8 4.2 4.7 5.8 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease PI3K_1B_p101 PF10486.9 EWM27904.1 - 3.2 5.4 4.9 4.2 5.0 4.9 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RR_TM4-6 PF06459.12 EWM27904.1 - 3.3 7.5 12.8 6 6.6 12.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Dsh_C PF12316.8 EWM27904.1 - 3.9 7.8 6.9 9.7 6.5 6.9 1.7 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF913 PF06025.12 EWM27904.1 - 5.1 6.0 7.8 8 5.3 7.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) GOLD_2 PF13897.6 EWM27904.1 - 5.9 7.4 13.0 12 6.4 13.0 1.5 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking NPR3 PF03666.13 EWM27904.1 - 6.9 5.3 6.5 9.7 4.8 6.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DNA_pol_phi PF04931.13 EWM27904.1 - 7.7 4.5 22.2 11 3.9 22.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi Pyr_redox_2 PF07992.14 EWM27905.1 - 3.1e-64 217.0 1.4 4e-64 216.7 1.4 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EWM27905.1 - 3.8e-28 98.0 0.0 7.3e-28 97.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EWM27905.1 - 1.8e-18 66.9 0.6 9e-15 55.0 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EWM27905.1 - 5.2e-17 62.0 0.0 4.9e-14 52.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EWM27905.1 - 1.2e-07 31.5 0.6 1.1e-06 28.3 0.8 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 EWM27905.1 - 2.4e-06 26.9 0.4 1.5e-05 24.3 0.2 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 EWM27905.1 - 4e-06 25.8 0.9 0.093 11.4 0.9 3.2 3 0 0 3 3 3 3 HI0933-like protein K_oxygenase PF13434.6 EWM27905.1 - 5.8e-06 25.7 0.0 2.8e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 EWM27905.1 - 0.0011 18.4 0.2 0.089 12.1 0.4 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EWM27905.1 - 0.0066 15.8 0.0 2.1 7.7 0.0 2.5 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EWM27905.1 - 0.025 15.0 0.1 1.8 9.0 0.1 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.24 EWM27905.1 - 0.045 12.8 9.1 0.021 13.9 3.2 2.8 3 0 0 3 3 3 0 FAD binding domain NAD_binding_8 PF13450.6 EWM27905.1 - 0.11 12.7 1.9 0.37 11.1 1.9 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 EWM27905.1 - 0.12 12.3 1.8 2.4 8.0 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 EWM27905.1 - 0.15 11.2 0.2 0.31 10.2 0.2 1.4 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 EWM27905.1 - 5.4 6.5 12.6 0.32 10.5 4.2 2.9 3 1 0 4 4 4 0 FAD dependent oxidoreductase CBS PF00571.28 EWM27906.1 - 6.7e-07 29.7 0.0 1.1e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 CBS domain LRR_6 PF13516.6 EWM27907.1 - 1.9e-08 33.7 13.7 1.1 9.5 0.7 8.0 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.7 EWM27907.1 - 0.00016 22.0 13.5 0.82 10.2 0.6 7.2 8 2 0 8 8 8 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EWM27907.1 - 0.00018 21.2 12.4 0.46 10.3 0.6 6.2 5 1 0 5 5 5 3 Leucine rich repeat LRR_1 PF00560.33 EWM27907.1 - 2.5 9.0 17.6 22 6.1 0.1 7.6 9 0 0 9 9 9 0 Leucine Rich Repeat AAA PF00004.29 EWM27908.1 - 1e-42 145.7 0.0 1.6e-42 145.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EWM27908.1 - 4.6e-06 26.3 0.1 8.7e-06 25.4 0.1 1.4 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EWM27908.1 - 3.2e-05 23.7 0.0 0.00012 21.8 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 EWM27908.1 - 0.00053 19.8 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 EWM27908.1 - 0.00057 20.3 5.6 0.0056 17.1 0.1 3.0 2 2 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EWM27908.1 - 0.00059 20.1 0.1 0.017 15.4 0.1 2.4 1 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EWM27908.1 - 0.0015 18.7 0.0 0.0034 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EWM27908.1 - 0.0019 18.2 0.2 0.022 14.7 0.1 2.8 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EWM27908.1 - 0.0028 16.9 0.0 0.0042 16.4 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 EWM27908.1 - 0.0034 17.9 0.0 0.012 16.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EWM27908.1 - 0.0034 17.0 1.5 0.012 15.2 0.3 2.3 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EWM27908.1 - 0.0048 17.1 0.7 0.088 13.0 0.0 2.6 2 1 1 3 3 3 1 AAA domain Mg_chelatase PF01078.21 EWM27908.1 - 0.0052 16.2 0.5 0.016 14.6 0.1 1.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 EWM27908.1 - 0.021 14.9 0.0 0.055 13.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 EWM27908.1 - 0.023 15.1 0.0 0.039 14.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 EWM27908.1 - 0.026 14.5 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 EWM27908.1 - 0.03 14.1 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 EWM27908.1 - 0.035 13.2 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase PF06745.13 EWM27908.1 - 0.05 12.9 0.0 0.085 12.2 0.0 1.2 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.26 EWM27908.1 - 0.066 12.9 0.0 0.5 10.1 0.0 2.3 3 0 0 3 3 3 0 Sigma-54 interaction domain PhoH PF02562.16 EWM27908.1 - 0.077 12.4 0.3 0.19 11.2 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein NACHT PF05729.12 EWM27908.1 - 0.12 12.2 0.2 0.91 9.4 0.1 2.0 2 0 0 2 2 2 0 NACHT domain AAA_3 PF07726.11 EWM27908.1 - 0.13 12.1 0.0 0.36 10.7 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EWM27908.1 - 0.16 11.5 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2075 PF09848.9 EWM27908.1 - 0.19 10.9 0.0 0.25 10.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Pox_A_type_inc PF04508.12 EWM27908.1 - 0.21 11.5 0.5 0.43 10.5 0.5 1.4 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Pkinase PF00069.25 EWM27909.1 - 6.8e-33 114.2 0.0 1e-32 113.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM27909.1 - 1.8e-23 83.1 0.0 1.8e-22 79.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EWM27909.1 - 0.0002 20.8 0.0 0.00039 19.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EWM27909.1 - 0.00022 20.6 0.2 0.015 14.6 0.1 2.8 2 1 0 2 2 2 1 Kinase-like TMF_TATA_bd PF12325.8 EWM27909.1 - 0.017 15.3 3.0 1.8 8.8 0.1 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Chibby PF14645.6 EWM27909.1 - 0.02 15.3 1.0 0.042 14.3 0.0 1.9 2 0 0 2 2 2 0 Chibby family APH PF01636.23 EWM27909.1 - 0.021 14.8 0.1 0.021 14.8 0.1 3.2 2 2 1 3 3 3 0 Phosphotransferase enzyme family ATG16 PF08614.11 EWM27909.1 - 0.42 10.8 5.7 2.8 8.1 0.1 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) HOOK PF05622.12 EWM27909.1 - 0.43 8.7 3.2 0.31 9.2 0.9 1.7 2 0 0 2 2 2 0 HOOK protein Cnn_1N PF07989.11 EWM27909.1 - 0.46 10.7 4.5 2.7 8.2 1.4 2.3 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF1995 PF09353.10 EWM27910.1 - 2e-25 90.0 0.0 2.8e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) SRPRB PF09439.10 EWM27910.1 - 0.21 11.0 0.1 0.32 10.4 0.1 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Voltage_CLC PF00654.20 EWM27911.1 - 0.0003 20.2 1.2 0.061 12.6 0.0 2.1 1 1 1 2 2 2 2 Voltage gated chloride channel LCE PF14672.6 EWM27911.1 - 0.037 14.6 7.7 0.037 14.6 7.7 1.8 2 0 0 2 2 2 0 Late cornified envelope DUF2530 PF10745.9 EWM27911.1 - 0.051 13.8 0.5 0.11 12.8 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) Spt20 PF12090.8 EWM27911.1 - 1.3 8.6 7.7 1.9 8.1 7.7 1.3 1 0 0 1 1 1 0 Spt20 family SR-25 PF10500.9 EWM27911.1 - 1.6 8.3 12.4 3.5 7.2 12.4 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3797 PF12677.7 EWM27912.1 - 0.0016 18.2 0.6 0.06 13.3 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3797) zf-LSD1 PF06943.12 EWM27912.1 - 0.014 15.2 0.9 0.089 12.6 0.0 2.3 2 0 0 2 2 2 0 LSD1 zinc finger Zn_Tnp_IS91 PF14319.6 EWM27912.1 - 0.025 14.6 0.1 0.041 13.9 0.1 1.3 1 0 0 1 1 1 0 Transposase zinc-binding domain hNIFK_binding PF12196.8 EWM27912.1 - 0.28 10.7 1.5 0.49 9.9 1.5 1.4 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK eIF-5_eIF-2B PF01873.17 EWM27912.1 - 0.43 10.5 1.9 3.4 7.6 0.0 2.1 1 1 1 2 2 2 0 Domain found in IF2B/IF5 Hist_deacetyl PF00850.19 EWM27914.1 - 2.2e-78 263.8 0.0 3.8e-78 263.1 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain ECH_1 PF00378.20 EWM27915.1 - 3.7e-59 200.0 0.0 4.6e-59 199.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EWM27915.1 - 1.9e-29 103.2 0.1 2.9e-26 92.7 0.2 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase DUF647 PF04884.14 EWM27916.1 - 1.4e-79 267.2 1.9 1.8e-79 266.8 1.9 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DUF4487 PF14868.6 EWM27916.1 - 0.15 10.9 0.1 0.21 10.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4487) DUF3938 PF13074.6 EWM27916.1 - 0.18 12.0 2.2 16 5.8 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3938) AAA_33 PF13671.6 EWM27917.1 - 0.0012 19.0 0.1 0.0096 16.1 0.0 2.1 1 1 2 3 3 3 1 AAA domain ABC2_membrane PF01061.24 EWM27919.1 - 2e-27 96.0 25.4 3.2e-27 95.3 25.4 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EWM27919.1 - 1.5e-18 67.6 0.0 2.4e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EWM27919.1 - 1.1e-09 38.5 0.0 0.00058 19.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EWM27919.1 - 9.4e-05 23.0 0.9 0.00018 22.1 0.9 1.4 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 EWM27919.1 - 0.00032 20.2 0.0 0.71 9.3 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 EWM27919.1 - 0.0017 17.6 20.3 0.0017 17.6 20.3 1.6 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_29 PF13555.6 EWM27919.1 - 0.004 16.9 0.1 0.012 15.4 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EWM27919.1 - 0.0053 16.7 0.0 0.0092 15.9 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EWM27919.1 - 0.007 16.8 0.0 0.015 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EWM27919.1 - 0.033 14.5 0.0 0.19 12.0 0.0 2.2 2 1 1 3 3 3 0 AAA domain AAA_18 PF13238.6 EWM27919.1 - 0.042 14.4 0.0 0.44 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EWM27919.1 - 0.13 11.8 0.8 0.28 10.7 0.4 1.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EWM27919.1 - 0.14 11.9 0.0 0.34 10.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 EWM27919.1 - 0.17 10.6 0.2 0.27 10.0 0.2 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class PPR_2 PF13041.6 EWM27920.1 - 2.1e-31 107.9 0.1 2.1e-06 27.8 0.0 9.5 7 2 3 10 10 10 7 PPR repeat family PPR PF01535.20 EWM27920.1 - 9.6e-31 103.9 18.4 2.8e-05 24.0 0.1 11.9 12 0 0 12 12 12 6 PPR repeat PPR_3 PF13812.6 EWM27920.1 - 1.9e-14 53.5 0.0 3e-09 36.8 0.0 5.3 6 0 0 6 6 6 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 EWM27920.1 - 2.1e-11 43.3 0.1 0.017 14.8 0.0 7.1 10 0 0 10 10 10 3 PPR repeat PPR_long PF17177.4 EWM27920.1 - 7.7e-08 32.0 0.0 2.8e-05 23.6 0.0 2.8 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP TPR_10 PF13374.6 EWM27920.1 - 0.0017 18.2 3.3 2.1 8.4 0.0 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EWM27920.1 - 0.0042 17.0 1.1 14 5.9 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 EWM27920.1 - 0.018 15.6 7.6 25 5.5 0.0 6.6 7 1 0 8 8 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 EWM27920.1 - 0.052 13.9 9.3 5.3 7.4 0.0 5.8 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 EWM27920.1 - 0.091 12.9 3.5 32 5.0 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EWM27920.1 - 1 10.2 6.7 1.5e+02 3.4 0.0 5.8 7 0 0 7 7 5 0 Tetratricopeptide repeat Methyltransf_11 PF08241.12 EWM27921.1 - 7.4e-13 49.0 0.0 1.9e-12 47.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM27921.1 - 1.2e-06 29.1 0.0 3.2e-06 27.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM27921.1 - 1.7e-06 27.9 0.0 2.8e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EWM27921.1 - 6.5e-05 23.6 0.0 0.00015 22.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EWM27921.1 - 0.00064 19.1 0.0 0.00089 18.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EWM27921.1 - 0.0022 17.8 0.0 0.0049 16.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 EWM27921.1 - 0.016 13.8 0.0 0.023 13.3 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.15 EWM27921.1 - 0.068 13.0 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase SNARE PF05739.19 EWM27922.1 - 4.2e-10 39.5 3.5 5.9e-10 39.0 0.5 2.4 2 0 0 2 2 2 1 SNARE domain RmuC PF02646.16 EWM27922.1 - 0.32 10.1 5.2 1.5 7.9 0.8 2.5 2 1 0 2 2 2 0 RmuC family NPV_P10 PF05531.12 EWM27922.1 - 3.7 8.1 6.7 75 3.9 0.1 3.8 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Methyltransf_8 PF05148.15 EWM27923.1 - 1.4e-63 214.7 0.2 3.6e-62 210.1 0.0 2.6 2 1 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 EWM27923.1 - 0.00037 21.1 0.2 0.00069 20.2 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM27923.1 - 0.016 15.9 0.1 0.033 14.9 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain DMPK_coil PF08826.10 EWM27924.1 - 1.9 8.7 5.1 9.9 6.4 5.1 2.2 1 1 0 1 1 1 0 DMPK coiled coil domain like PKD_channel PF08016.12 EWM27927.1 - 1.4e-08 33.9 2.4 2.5e-08 33.0 2.4 1.3 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 EWM27927.1 - 0.00034 19.9 18.0 0.0019 17.5 18.0 2.0 1 1 0 1 1 1 1 Ion transport protein MS_channel PF00924.18 EWM27928.1 - 1.6e-20 73.6 4.4 2e-20 73.3 2.3 1.9 2 0 0 2 2 2 1 Mechanosensitive ion channel PTS_EIIC_2 PF13303.6 EWM27928.1 - 0.62 9.0 7.0 0.17 10.8 4.1 1.4 2 0 0 2 2 2 0 Phosphotransferase system, EIIC COPIIcoated_ERV PF07970.12 EWM27929.1 - 4.8e-29 101.8 0.0 6.7e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EWM27929.1 - 1.5e-16 60.5 0.1 3.5e-16 59.3 0.1 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Abhydrolase_6 PF12697.7 EWM27930.1 - 1.7e-08 35.3 2.4 4e-08 34.1 2.4 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EWM27930.1 - 2.3e-05 23.8 0.2 2.3e-05 23.8 0.2 2.9 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 EWM27930.1 - 0.08 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Mannitol_dh_C PF08125.13 EWM27932.1 - 1.3e-05 24.8 0.0 0.00027 20.5 0.0 2.3 1 1 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain OsmC PF02566.19 EWM27933.1 - 5.8e-14 52.4 0.0 9.1e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein LRRNT PF01462.18 EWM27933.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain SF-assemblin PF06705.11 EWM27934.1 - 4.1e-34 118.0 18.5 4.7e-34 117.8 18.5 1.0 1 0 0 1 1 1 1 SF-assemblin/beta giardin T2SSF PF00482.23 EWM27934.1 - 0.04 13.9 5.4 0.11 12.5 5.4 1.8 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F HK97-gp10_like PF04883.12 EWM27934.1 - 0.069 14.1 2.4 0.63 11.1 0.4 2.5 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component YqhG PF11079.8 EWM27934.1 - 1.1 8.1 3.1 5.8 5.8 0.9 2.1 2 0 0 2 2 2 0 Bacterial protein YqhG of unknown function ApoLp-III PF07464.11 EWM27934.1 - 7.6 6.6 9.2 4.9 7.2 2.6 3.1 2 2 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Prefoldin_2 PF01920.20 EWM27935.1 - 2.2e-15 56.5 1.0 2.2e-15 56.5 1.0 2.1 2 0 0 2 2 2 1 Prefoldin subunit TPR_1 PF00515.28 EWM27935.1 - 6.3e-11 41.6 6.4 1.7e-06 27.6 0.5 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EWM27935.1 - 1.4e-10 40.4 13.5 3.2e-06 26.8 0.5 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 EWM27935.1 - 1.9e-08 33.9 1.8 1.1e-06 28.2 0.3 2.9 2 1 1 3 3 3 1 TPR repeat TPR_14 PF13428.6 EWM27935.1 - 4.7e-08 33.2 6.5 0.0011 19.6 0.1 4.0 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EWM27935.1 - 4.5e-07 30.4 12.6 1.2e-05 25.9 0.4 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EWM27935.1 - 2.2e-06 27.4 2.0 0.034 14.4 0.4 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EWM27935.1 - 6.3e-06 26.6 4.0 0.013 16.0 1.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 EWM27935.1 - 0.00073 20.0 5.4 0.25 12.0 0.1 3.6 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EWM27935.1 - 0.0016 18.3 0.7 3.2 8.0 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EWM27935.1 - 0.0021 18.1 2.0 0.0038 17.3 0.3 2.3 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 EWM27935.1 - 0.0022 18.2 1.9 20 5.8 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TOM20_plant PF06552.12 EWM27935.1 - 0.0059 16.4 1.7 0.72 9.6 1.7 2.2 1 1 0 1 1 1 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_9 PF13371.6 EWM27935.1 - 0.0081 16.3 1.0 0.33 11.1 0.6 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EWM27935.1 - 0.011 16.1 3.2 0.072 13.4 0.8 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat Sugarporin_N PF11471.8 EWM27935.1 - 0.012 15.6 6.4 0.076 13.0 1.2 2.9 1 1 1 2 2 2 0 Maltoporin periplasmic N-terminal extension DUF4778 PF16008.5 EWM27935.1 - 0.7 9.9 3.5 1.2 9.1 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) COQ9 PF08511.11 EWM27936.1 - 5.8e-23 80.4 0.1 1.3e-22 79.4 0.1 1.6 1 0 0 1 1 1 1 COQ9 T4_tail_cap PF11091.8 EWM27936.1 - 0.051 12.5 0.8 0.096 11.6 0.1 1.7 2 0 0 2 2 2 0 Tail-tube assembly protein Trypsin_2 PF13365.6 EWM27937.1 - 2.1e-32 113.1 2.8 3e-32 112.6 2.8 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 EWM27937.1 - 1.6e-16 60.8 0.1 2.2e-16 60.3 0.1 1.2 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 EWM27937.1 - 2.1e-13 50.4 0.0 4e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EWM27937.1 - 1.2e-10 41.0 0.1 3e-10 39.8 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EWM27937.1 - 1.7e-07 31.5 0.2 4.4e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 PDZ domain Peptidase_S46 PF10459.9 EWM27937.1 - 4e-06 25.8 0.8 0.044 12.4 0.1 2.1 2 0 0 2 2 2 2 Peptidase S46 GRASP55_65 PF04495.14 EWM27937.1 - 0.0034 17.7 0.0 0.006 16.9 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain Tricorn_PDZ PF14685.6 EWM27937.1 - 0.0081 16.1 0.1 0.022 14.7 0.1 1.7 1 0 0 1 1 1 1 Tricorn protease PDZ domain Peptidase_S32 PF05579.13 EWM27937.1 - 0.021 14.0 1.9 1.5 7.9 1.9 2.2 1 1 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 LSM PF01423.22 EWM27937.1 - 0.068 12.9 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 LSM domain SET PF00856.28 EWM27938.1 - 5.7e-08 33.3 0.0 1.9e-06 28.4 0.0 2.2 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 EWM27938.1 - 0.00069 19.6 2.4 0.00069 19.6 2.4 2.2 2 0 0 2 2 2 1 MYND finger TPIP1 PF15338.6 EWM27938.1 - 0.063 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 p53-regulated apoptosis-inducing protein 1 CCT PF06203.14 EWM27939.1 - 7.1e-06 26.0 9.1 1.2e-05 25.2 9.1 1.4 1 0 0 1 1 1 1 CCT motif DUF2744 PF10910.8 EWM27939.1 - 1.1 9.3 4.7 1.9 8.5 0.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2744) Pyr_redox_2 PF07992.14 EWM27940.1 - 2e-37 129.0 0.0 2.6e-37 128.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EWM27940.1 - 1.7e-10 41.3 0.1 3.9e-09 36.9 0.2 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase MIR PF02815.19 EWM27941.1 - 4.7e-12 46.1 0.2 9.7e-08 32.1 0.0 3.2 1 1 1 2 2 2 2 MIR domain MIR PF02815.19 EWM27942.1 - 3.6e-12 46.5 0.1 2.3e-07 30.8 0.0 3.3 1 1 1 2 2 2 2 MIR domain NUDIX PF00293.28 EWM27943.1 - 8.9e-12 45.2 0.3 1.6e-11 44.4 0.3 1.4 1 0 0 1 1 1 1 NUDIX domain CAP_N PF01213.19 EWM27945.1 - 1.1 8.6 5.8 3.3 7.1 5.8 1.7 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Pro_isomerase PF00160.21 EWM27946.1 - 2.6e-12 47.3 0.0 4.7e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CCDC24 PF15669.5 EWM27946.1 - 7.8 6.3 6.4 13 5.6 6.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family RHD3 PF05879.12 EWM27948.1 - 0.00044 18.6 0.5 0.00056 18.2 0.5 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GMC_oxred_N PF00732.19 EWM27948.1 - 0.024 14.0 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 GMC oxidoreductase Activator_LAG-3 PF11498.8 EWM27948.1 - 1.1 8.1 12.4 1.8 7.5 12.4 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Epimerase PF01370.21 EWM27949.1 - 2.4e-20 73.0 0.0 4.3e-20 72.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EWM27949.1 - 1.2e-17 63.8 0.0 1.8e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EWM27949.1 - 2.2e-16 60.2 0.0 5e-16 59.0 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EWM27949.1 - 1e-10 41.2 0.0 8.1e-10 38.3 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 EWM27949.1 - 4.9e-08 32.4 0.0 2.4e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EWM27949.1 - 1.8e-05 24.0 0.0 6e-05 22.3 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 EWM27949.1 - 0.018 15.0 0.2 0.066 13.1 0.2 1.8 1 1 0 1 1 1 0 KR domain PRORP PF16953.5 EWM27950.1 - 3.8e-40 137.9 0.0 5.8e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 Protein-only RNase P PPR_long PF17177.4 EWM27950.1 - 5.3e-31 107.6 0.0 7.9e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 EWM27950.1 - 3.5e-14 52.7 0.0 8.5e-05 22.7 0.0 3.8 3 1 1 4 4 4 2 PPR repeat family PPR_3 PF13812.6 EWM27950.1 - 8.2e-09 35.4 0.0 0.0044 17.1 0.0 2.3 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR PF01535.20 EWM27950.1 - 6.9e-08 32.2 0.0 0.0079 16.4 0.0 4.0 3 1 0 3 3 3 2 PPR repeat RNase_Zc3h12a PF11977.8 EWM27950.1 - 0.00012 21.9 0.0 0.0003 20.6 0.0 1.5 1 1 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain PPR_1 PF12854.7 EWM27950.1 - 0.00013 21.6 0.1 0.0029 17.3 0.0 2.8 3 0 0 3 3 3 1 PPR repeat TF_Zn_Ribbon PF08271.12 EWM27950.1 - 0.16 11.5 0.1 0.35 10.4 0.1 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding TPR_14 PF13428.6 EWM27950.1 - 3.7 8.6 11.4 13 6.9 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3450 PF11932.8 EWM27951.1 - 0.00059 19.2 7.8 0.00059 19.2 7.8 12.5 3 2 8 12 12 12 3 Protein of unknown function (DUF3450) ABC1 PF03109.16 EWM27952.1 - 1.8e-28 99.1 0.0 5e-28 97.7 0.0 1.8 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EWM27952.1 - 0.00057 19.9 0.3 0.0017 18.3 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 EWM27952.1 - 0.019 14.3 0.1 2 7.7 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain EF-hand_8 PF13833.6 EWM27953.1 - 3.4e-23 81.2 4.1 2.8e-12 46.3 0.8 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.6 EWM27953.1 - 9.8e-22 77.2 1.6 8.7e-10 38.9 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EWM27953.1 - 1.7e-17 61.6 7.6 1.2e-07 30.7 0.4 4.2 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 EWM27953.1 - 3.7e-15 54.5 4.3 3.2e-05 23.5 0.1 4.2 3 1 0 4 4 4 3 EF-hand domain EF-hand_9 PF14658.6 EWM27953.1 - 2.5e-12 47.0 0.1 9.9e-09 35.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EWM27953.1 - 6.2e-09 35.0 5.5 0.00014 21.2 0.1 3.6 4 1 0 4 4 4 2 EF hand EF-hand_4 PF12763.7 EWM27953.1 - 0.00033 20.6 0.1 0.51 10.3 0.1 2.2 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 EWM27953.1 - 0.0055 16.7 0.0 1.2 9.0 0.0 2.8 2 1 1 3 3 3 1 Caleosin related protein DUF3008 PF11450.8 EWM27953.1 - 0.006 16.7 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknwon function (DUF3008) Hydrolase_4 PF12146.8 EWM27953.1 - 0.0097 15.2 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 MotA_activ PF09114.10 EWM27953.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Transcription factor MotA, activation domain Glycos_transf_1 PF00534.20 EWM27954.1 - 4.4e-24 84.9 0.0 6.8e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EWM27954.1 - 1.3e-21 77.4 0.0 3.7e-21 76.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EWM27954.1 - 2.1e-15 57.1 0.0 5.8e-15 55.7 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EWM27954.1 - 1.6e-07 31.9 0.0 6.9e-07 29.8 0.0 2.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EWM27954.1 - 0.0013 19.1 0.0 0.0038 17.6 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 GSDH PF07995.11 EWM27955.1 - 2.2e-22 79.8 0.0 9.2e-22 77.8 0.0 1.9 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase CENP-C_C PF11699.8 EWM27956.1 - 0.0028 17.8 0.0 0.12 12.6 0.0 2.4 2 0 0 2 2 2 1 Mif2/CENP-C like DinB_2 PF12867.7 EWM27956.1 - 0.004 17.7 0.0 0.012 16.1 0.0 1.9 1 0 0 1 1 1 1 DinB superfamily Mif2_N PF15624.6 EWM27956.1 - 0.008 16.9 4.6 0.008 16.9 4.6 3.3 3 1 0 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.11 EWM27956.1 - 0.0093 15.7 0.0 0.055 13.2 0.0 2.4 2 0 0 2 2 2 1 Cupin domain DUF4674 PF15719.5 EWM27956.1 - 0.18 11.8 4.1 0.47 10.5 4.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) Ribosomal_L3 PF00297.22 EWM27957.1 - 4.6e-20 71.9 0.9 5.9e-18 65.0 0.3 2.2 1 1 1 2 2 2 2 Ribosomal protein L3 SYS1 PF09801.9 EWM27958.1 - 1.3e-40 138.8 1.3 1.5e-40 138.7 1.3 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network zf-CCCH_4 PF18044.1 EWM27959.1 - 4.7e-09 35.8 5.2 8.6e-09 35.0 5.2 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger Med26 PF08711.11 EWM27959.1 - 0.005 16.8 0.3 0.011 15.7 0.3 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain zf_CCCH_4 PF18345.1 EWM27959.1 - 0.0052 16.8 3.0 0.0052 16.8 3.0 1.8 2 0 0 2 2 2 1 Zinc finger domain GPP34 PF05719.11 EWM27959.1 - 0.0097 16.0 2.2 0.023 14.7 2.2 1.6 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) zf-CCCH PF00642.24 EWM27959.1 - 0.021 14.8 4.5 0.054 13.4 4.5 1.7 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) NMD3 PF04981.13 EWM27960.1 - 6.3e-57 192.8 0.1 8.8e-57 192.4 0.1 1.2 1 0 0 1 1 1 1 NMD3 family Yippee-Mis18 PF03226.14 EWM27960.1 - 0.011 15.9 0.0 0.025 14.8 0.0 1.6 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF3117 PF11314.8 EWM27960.1 - 0.017 14.9 0.1 0.054 13.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3117) HypA PF01155.19 EWM27960.1 - 2.2 8.3 7.5 0.73 9.9 0.4 2.7 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA CTD_bind PF04818.13 EWM27961.1 - 1.5e-12 48.2 0.0 4.5e-12 46.6 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. SKA1 PF07160.12 EWM27961.1 - 3.1 7.6 10.3 11 5.8 7.2 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 CTD_bind PF04818.13 EWM27962.1 - 1.4e-12 48.2 0.0 4.3e-12 46.7 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. SKA1 PF07160.12 EWM27962.1 - 3 7.6 10.3 10 5.9 7.2 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 eIF-1a PF01176.19 EWM27963.1 - 1.1e-23 82.8 0.3 1.5e-23 82.4 0.3 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 eIF-1a PF01176.19 EWM27964.1 - 1.1e-23 82.8 0.3 1.5e-23 82.4 0.3 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 DUF900 PF05990.12 EWM27965.1 - 0.0003 20.4 0.3 0.00093 18.8 0.3 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Thioesterase PF00975.20 EWM27965.1 - 0.0026 17.9 1.1 0.0046 17.1 1.1 1.4 1 0 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.25 EWM27965.1 - 0.028 14.3 0.2 0.45 10.4 0.1 2.3 2 0 0 2 2 2 0 Lipase (class 3) Ser_hydrolase PF06821.13 EWM27965.1 - 0.081 12.8 5.5 0.15 11.9 5.5 1.4 1 0 0 1 1 1 0 Serine hydrolase Hydrolase_4 PF12146.8 EWM27967.1 - 0.00017 20.9 0.0 0.0003 20.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EWM27967.1 - 0.00033 20.4 0.2 0.011 15.3 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EWM27967.1 - 0.046 13.4 0.1 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 Putative esterase NUDIX PF00293.28 EWM27968.1 - 1.7e-11 44.3 0.0 3.3e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain DUF1266 PF06889.11 EWM27968.1 - 0.11 12.6 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) RPN2_C PF18004.1 EWM27971.1 - 0.037 13.9 0.1 0.053 13.4 0.1 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain NOA36 PF06524.12 EWM27971.1 - 2.3 7.4 4.8 3.2 7.0 4.8 1.1 1 0 0 1 1 1 0 NOA36 protein DUF1118 PF06549.12 EWM27972.1 - 3.5e-06 27.3 7.5 3.5e-06 27.3 7.5 2.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1118) DUF1499 PF07386.11 EWM27973.1 - 1.6e-13 51.2 0.0 2.6e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1499) PNTB_4TM PF12769.7 EWM27973.1 - 0.16 12.5 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 4TM region of pyridine nucleotide transhydrogenase, mitoch RelA_SpoT PF04607.17 EWM27974.1 - 3.7e-23 82.0 0.0 1e-22 80.6 0.0 1.8 1 1 0 1 1 1 1 Region found in RelA / SpoT proteins HD_4 PF13328.6 EWM27974.1 - 1.7e-14 53.8 0.3 3.2e-14 52.9 0.3 1.4 1 0 0 1 1 1 1 HD domain CaM_binding PF07839.11 EWM27974.1 - 0.017 15.9 0.0 0.051 14.3 0.0 1.8 1 0 0 1 1 1 0 Plant calmodulin-binding domain TGS PF02824.21 EWM27974.1 - 0.15 12.2 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 TGS domain COX15-CtaA PF02628.15 EWM27976.1 - 3.8e-107 358.1 11.3 2.2e-106 355.6 11.3 1.8 1 1 0 1 1 1 1 Cytochrome oxidase assembly protein CTP_transf_1 PF01148.20 EWM27977.1 - 4e-61 207.1 22.4 2.4e-60 204.6 22.4 1.9 1 1 0 1 1 1 1 Cytidylyltransferase family SNAP PF14938.6 EWM27979.1 - 0.0053 16.2 0.0 0.0092 15.4 0.0 1.3 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 EWM27979.1 - 0.015 15.3 1.7 0.1 12.7 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EWM27979.1 - 0.031 14.4 1.7 1.9 8.8 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Hira PF07569.11 EWM27979.1 - 0.1 12.3 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 TUP1-like enhancer of split TPR_14 PF13428.6 EWM27979.1 - 0.3 12.0 8.6 12 7.0 0.3 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 EWM27979.1 - 7.1 6.6 11.6 0.1 12.5 0.4 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EWM27979.1 - 8.1 6.8 7.1 1.2 9.4 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Lipase_3 PF01764.25 EWM27980.1 - 1.4e-16 60.7 0.0 4.1e-16 59.1 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 EWM27980.1 - 0.0003 20.6 0.0 0.00051 19.8 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EWM27980.1 - 0.00073 20.2 0.1 0.00073 20.2 0.1 3.2 3 0 0 3 3 3 1 Alpha/beta hydrolase family DUF2974 PF11187.8 EWM27980.1 - 0.012 15.1 0.0 2.1 7.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 EWM27980.1 - 0.18 11.1 0.0 0.36 10.1 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF676 PF05057.14 EWM27980.1 - 0.21 11.1 0.0 0.38 10.2 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 EWM27981.1 - 2.8e-23 83.7 0.4 4e-23 83.2 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EWM27981.1 - 3.4e-19 69.0 0.0 9.9e-16 57.7 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EWM27981.1 - 1.8e-14 54.0 0.2 2.1e-11 44.0 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 EWM27981.1 - 4.1e-05 23.4 0.0 0.0048 16.7 0.0 3.0 3 0 0 3 3 3 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 EWM27981.1 - 0.00082 19.0 0.0 0.36 10.4 0.0 2.2 2 0 0 2 2 2 2 Lipid-droplet associated hydrolase Thioesterase PF00975.20 EWM27981.1 - 0.0091 16.1 0.0 0.084 13.0 0.0 2.2 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_4 PF08386.10 EWM27981.1 - 0.034 14.3 0.0 0.086 13.0 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein UPF0227 PF05728.12 EWM27981.1 - 0.036 14.0 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) SLT_L PF14718.6 EWM27981.1 - 0.1 12.7 0.2 2.5 8.3 0.1 2.5 2 0 0 2 2 2 0 Soluble lytic murein transglycosylase L domain Peptidase_S9 PF00326.21 EWM27981.1 - 0.16 11.4 0.0 1.2 8.5 0.0 2.4 2 1 0 2 2 2 0 Prolyl oligopeptidase family Ldh_1_N PF00056.23 EWM27982.1 - 2.4e-29 102.2 0.1 3.9e-29 101.5 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EWM27982.1 - 2e-13 50.6 0.2 1.1e-12 48.3 0.2 2.1 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain CofC PF01983.16 EWM27982.1 - 0.13 11.4 0.0 0.38 9.9 0.0 1.7 2 0 0 2 2 2 0 Guanylyl transferase CofC like 2TM PF13239.6 EWM27983.1 - 0.0005 20.3 6.2 0.0013 19.0 6.2 1.7 1 0 0 1 1 1 1 2TM domain Fe_bilin_red PF05996.12 EWM27984.1 - 2e-49 168.3 0.0 2.4e-49 168.1 0.0 1.1 1 0 0 1 1 1 1 Ferredoxin-dependent bilin reductase RRP7 PF12923.7 EWM27985.1 - 3.5e-32 111.0 13.7 3.5e-32 111.0 13.7 1.9 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 EWM27985.1 - 1.7e-06 27.9 0.1 4.6e-06 26.5 0.1 1.7 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 EWM27985.1 - 0.02 15.0 0.0 0.066 13.3 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif AAA_23 PF13476.6 EWM27985.1 - 0.032 14.7 3.9 0.049 14.1 3.9 1.3 1 0 0 1 1 1 0 AAA domain YscK PF06578.12 EWM27985.1 - 0.13 11.8 0.2 0.23 10.9 0.2 1.4 1 0 0 1 1 1 0 YOP proteins translocation protein K (YscK) Arg_decarbox_C PF17944.1 EWM27985.1 - 0.58 10.8 3.1 0.5 11.0 0.2 2.3 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension Fez1 PF06818.15 EWM27985.1 - 0.94 9.9 13.4 1.5 9.3 13.4 1.2 1 0 0 1 1 1 0 Fez1 DUF4404 PF14357.6 EWM27985.1 - 1.2 9.8 9.9 0.2 12.3 4.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF4407 PF14362.6 EWM27985.1 - 8.4 5.7 14.0 13 5.0 14.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_L21p PF00829.21 EWM27986.1 - 1.5e-27 95.8 4.6 1.9e-27 95.5 4.6 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein CCB2_CCB4 PF11152.8 EWM27987.1 - 2.1e-37 128.4 0.0 2.7e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Cofactor assembly of complex C subunit B, CCB2/CCB4 DUF1768 PF08719.11 EWM27988.1 - 1.3e-21 77.6 0.1 2.2e-21 76.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) RRM_1 PF00076.22 EWM27988.1 - 3.8e-11 42.6 0.0 1e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FHA PF00498.26 EWM27988.1 - 4.7e-08 33.3 0.0 8.5e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain Pyridoxal_deC PF00282.19 EWM27989.1 - 8.2e-17 61.0 0.0 1.5e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EWM27989.1 - 6.6e-07 28.6 0.0 1.1e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DUF4530 PF15039.6 EWM27989.1 - 0.0028 17.8 4.9 0.0039 17.3 3.9 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4530) Pkinase PF00069.25 EWM27991.1 - 1.3e-46 159.1 0.0 1.1e-30 106.9 0.0 2.8 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EWM27991.1 - 1.7e-32 112.7 0.0 1.1e-15 57.6 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.6 EWM27991.1 - 0.0015 17.9 0.0 0.0043 16.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like GCV_T PF01571.21 EWM27992.1 - 0.00061 19.2 0.0 0.00089 18.7 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DUF4033 PF13225.6 EWM27994.1 - 2.1e-24 85.3 0.2 3.8e-24 84.5 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4033) NAD_binding_2 PF03446.15 EWM27995.1 - 9.9e-46 155.8 3.4 1.4e-45 155.3 3.4 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EWM27995.1 - 5.8e-36 123.4 0.0 1.2e-35 122.3 0.0 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 EWM27995.1 - 1.7e-10 40.6 0.5 3.9e-10 39.4 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EWM27995.1 - 1.9e-06 28.4 0.0 3.9e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 EWM27995.1 - 7.8e-05 22.3 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 EWM27995.1 - 0.0036 17.2 0.4 0.0072 16.2 0.1 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 EWM27995.1 - 0.0045 17.2 0.0 0.0093 16.2 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain ApbA PF02558.16 EWM27995.1 - 0.027 14.1 1.0 0.18 11.5 0.0 2.5 2 1 1 3 3 3 0 Ketopantoate reductase PanE/ApbA FHA PF00498.26 EWM27996.1 - 2.9e-12 46.7 0.1 7.1e-12 45.5 0.1 1.6 1 0 0 1 1 1 1 FHA domain RINGv PF12906.7 EWM27996.1 - 1.1e-11 44.6 3.4 2.9e-11 43.3 3.4 1.8 1 1 0 1 1 1 1 RING-variant domain Yop-YscD_cpl PF16697.5 EWM27996.1 - 6.3e-07 29.6 0.0 5.8e-06 26.5 0.0 2.3 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain ABC_membrane PF00664.23 EWM27997.1 - 2.8e-35 122.3 15.1 4.8e-35 121.5 15.1 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EWM27997.1 - 3.8e-33 114.9 0.0 6.8e-33 114.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter MENTAL PF10457.9 EWM27997.1 - 0.00027 20.8 0.7 0.0006 19.7 0.7 1.5 1 0 0 1 1 1 1 Cholesterol-capturing domain AAA_16 PF13191.6 EWM27997.1 - 0.0013 19.2 0.4 0.0043 17.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 EWM27997.1 - 0.002 17.6 0.1 1.1 8.6 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EWM27997.1 - 0.015 15.4 0.0 0.05 13.7 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_membrane_3 PF13748.6 EWM27997.1 - 0.025 13.8 2.2 0.055 12.7 0.5 2.4 2 0 0 2 2 2 0 ABC transporter transmembrane region AAA_29 PF13555.6 EWM27997.1 - 0.03 14.1 0.2 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF87 PF01935.17 EWM27997.1 - 0.032 14.3 0.0 0.35 10.9 0.0 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 EWM27997.1 - 0.05 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase DUF4351 PF14261.6 EWM27997.1 - 0.081 13.0 0.0 0.26 11.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) 2-oxoacid_dh PF00198.23 EWM27998.1 - 3.4e-58 196.8 0.0 4.5e-58 196.4 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EWM27998.1 - 4.5e-15 55.2 0.3 8.3e-15 54.4 0.3 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EWM27998.1 - 8.6e-14 51.6 0.2 2.3e-13 50.2 0.2 1.8 1 0 0 1 1 1 1 e3 binding domain Tafi-CsgC PF10610.9 EWM27998.1 - 0.14 12.4 0.5 3.7 7.8 0.0 2.9 3 0 0 3 3 3 0 Thin aggregative fimbriae synthesis protein T2SSB PF16537.5 EWM27998.1 - 0.17 11.5 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system protein B DEC-1_N PF04625.13 EWM27998.1 - 3.4 6.6 15.7 5.4 5.9 15.7 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region IQ PF00612.27 EWM27999.1 - 0.0012 18.5 7.8 0.0015 18.1 1.8 2.6 2 0 0 2 2 2 2 IQ calmodulin-binding motif Uso1_p115_head PF04869.14 EWM28000.1 - 0.00066 18.9 0.0 0.0017 17.6 0.0 1.7 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region RT_RNaseH PF17917.1 EWM28000.1 - 0.09 13.1 0.7 0.56 10.5 0.0 2.8 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase RBD-FIP PF09457.10 EWM28000.1 - 0.53 10.3 6.2 20 5.2 0.6 4.8 2 0 0 2 2 2 0 FIP domain DUF1336 PF07059.12 EWM28001.1 - 1.2e-47 162.9 0.0 1.5e-47 162.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) Biopterin_H PF00351.21 EWM28002.1 - 5.9e-134 446.3 0.0 8.6e-134 445.8 0.0 1.2 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 EWM28002.1 - 9.8e-10 38.0 0.0 2.3e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 EWM28002.1 - 0.041 14.5 0.0 0.076 13.6 0.0 1.4 1 0 0 1 1 1 0 ACT domain Ribosomal_L27 PF01016.19 EWM28003.1 - 8.7e-34 115.4 1.3 1.1e-33 115.0 1.3 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein Ribosomal_60s PF00428.19 EWM28004.1 - 0.0055 17.3 8.5 0.0055 17.3 8.5 3.1 4 1 0 4 4 4 1 60s Acidic ribosomal protein Radial_spoke PF04712.12 EWM28004.1 - 0.041 12.8 8.7 0.079 11.9 8.7 1.4 1 0 0 1 1 1 0 Radial spokehead-like protein RIC3 PF15361.6 EWM28004.1 - 0.11 12.8 0.1 0.11 12.8 0.1 2.4 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 DUF4484 PF14831.6 EWM28004.1 - 0.35 10.9 2.6 3.2 7.8 1.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) DNA_pol_phi PF04931.13 EWM28004.1 - 0.42 8.7 12.4 0.79 7.8 12.4 1.3 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 EWM28004.1 - 1.4 8.1 9.1 4.1 6.7 9.1 1.7 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 EWM28004.1 - 5.1 6.8 10.7 0.24 11.0 3.0 2.7 3 0 0 3 3 3 0 FAM176 family Myc_N PF01056.18 EWM28004.1 - 9.3 6.0 10.1 3.3 7.5 6.8 1.8 2 0 0 2 2 2 0 Myc amino-terminal region Prenylcys_lyase PF07156.14 EWM28006.1 - 2.5e-67 227.6 0.0 3.1e-67 227.3 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 EWM28006.1 - 3.8e-11 43.0 0.2 7.5e-11 42.1 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EWM28006.1 - 1.8e-06 27.5 0.1 5.8e-06 25.8 0.1 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 EWM28006.1 - 3.2e-06 27.0 2.2 0.00036 20.2 0.6 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EWM28006.1 - 0.00023 20.5 1.0 0.0055 16.0 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EWM28006.1 - 0.072 13.1 0.9 0.28 11.2 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 EWM28006.1 - 0.093 13.3 0.2 0.26 11.9 0.2 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EWM28006.1 - 0.14 11.4 0.5 0.25 10.6 0.1 1.5 2 0 0 2 2 2 0 Thi4 family Pkinase PF00069.25 EWM28007.1 - 1.1e-64 218.3 0.0 1.5e-64 217.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM28007.1 - 5.4e-28 98.0 0.0 8.7e-28 97.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EWM28007.1 - 0.0021 18.0 0.4 0.013 15.4 0.3 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EWM28007.1 - 0.0053 15.7 0.0 0.0084 15.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EWM28007.1 - 0.0096 15.5 0.3 0.077 12.6 0.0 2.0 1 1 1 2 2 2 1 RIO1 family Kdo PF06293.14 EWM28007.1 - 0.037 13.4 0.8 0.062 12.7 0.8 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cytochrom_C PF00034.21 EWM28008.1 - 1.1e-08 36.1 0.0 2e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 EWM28008.1 - 1.1e-08 35.2 0.0 3.4e-08 33.7 0.0 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 EWM28008.1 - 4.8e-06 26.3 0.2 2e-05 24.3 0.2 1.9 1 1 0 1 1 1 1 Cytochrome c-550 domain Haem_bd PF14376.6 EWM28008.1 - 0.11 12.5 0.1 0.43 10.5 0.0 1.9 1 1 1 2 2 2 0 Haem-binding domain 60KD_IMP PF02096.20 EWM28009.1 - 4.9e-56 189.2 1.5 6.6e-56 188.8 1.5 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein Glyco_transf_20 PF00982.21 EWM28009.1 - 0.22 10.2 0.0 0.31 9.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 20 DUF2721 PF11026.8 EWM28010.1 - 1.5 8.7 6.0 16 5.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) CPSase_L_D2 PF02786.17 EWM28011.1 - 1.9e-112 373.9 0.3 4e-83 278.1 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 EWM28011.1 - 1.4e-50 170.4 0.0 3.2e-50 169.2 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 EWM28011.1 - 9.7e-40 136.4 0.0 4.5e-38 130.9 0.0 3.2 3 0 0 3 3 3 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 EWM28011.1 - 1.2e-34 119.2 0.0 3.5e-34 117.8 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 EWM28011.1 - 4.2e-18 65.5 0.1 2.1e-08 34.0 0.1 2.4 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.22 EWM28011.1 - 2.4e-16 59.7 0.0 1.4e-15 57.3 0.0 2.4 3 0 0 3 3 3 1 MGS-like domain Dala_Dala_lig_C PF07478.13 EWM28011.1 - 1.2e-14 54.3 0.1 5.4e-07 29.4 0.0 2.3 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 EWM28011.1 - 1e-11 44.7 0.1 9.5e-06 25.4 0.1 2.8 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 EWM28011.1 - 0.0054 16.8 0.0 1.9 8.5 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_5 PF13549.6 EWM28011.1 - 0.014 14.9 0.0 5.4 6.4 0.0 2.6 2 0 0 2 2 2 0 ATP-grasp domain Peptidase_C26 PF07722.13 EWM28011.1 - 0.02 14.7 1.3 0.44 10.3 0.0 3.0 3 0 0 3 3 3 0 Peptidase C26 GARS_A PF01071.19 EWM28011.1 - 0.04 13.7 0.8 0.2 11.4 0.1 2.4 3 0 0 3 3 3 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Mg-por_mtran_C PF07109.11 EWM28013.1 - 6e-36 122.7 0.3 1.3e-35 121.6 0.1 1.7 2 0 0 2 2 2 1 Magnesium-protoporphyrin IX methyltransferase C-terminus Methyltransf_25 PF13649.6 EWM28013.1 - 8.6e-12 45.6 0.1 2.1e-11 44.4 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EWM28013.1 - 1.5e-10 41.2 0.0 4.2e-10 39.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EWM28013.1 - 4.2e-09 37.0 0.0 9.9e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM28013.1 - 1.3e-06 28.3 0.0 2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM28013.1 - 4.2e-06 27.3 0.1 1.4e-05 25.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 EWM28013.1 - 9.2e-06 25.1 0.0 2.5e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 EWM28013.1 - 0.00035 20.1 0.2 0.00062 19.3 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 EWM28013.1 - 0.00059 19.3 0.4 0.0045 16.4 0.3 2.3 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EWM28013.1 - 0.0016 18.4 0.0 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EWM28013.1 - 0.0094 15.5 0.4 0.02 14.4 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.7 EWM28013.1 - 0.022 14.7 0.4 0.33 10.9 0.1 2.4 3 0 0 3 3 3 0 Methyltransferase domain CheR PF01739.18 EWM28013.1 - 0.11 12.0 0.1 2.2 7.7 0.0 2.2 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Met_10 PF02475.16 EWM28013.1 - 0.13 12.0 0.1 1.5 8.5 0.1 2.1 1 1 1 2 2 2 0 Met-10+ like-protein Methyltransf_30 PF05430.11 EWM28013.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase PepSY_2 PF13670.6 EWM28013.1 - 0.99 9.4 0.0 0.99 9.4 0.0 3.3 3 1 0 3 3 2 0 Peptidase propeptide and YPEB domain PWI PF01480.17 EWM28014.1 - 0.0033 17.7 0.0 0.0046 17.3 0.0 1.2 1 0 0 1 1 1 1 PWI domain Zip PF02535.22 EWM28015.1 - 0.75 8.9 2.6 0.97 8.6 2.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 EWM28015.1 - 1.6 7.4 3.0 2 7.1 3.0 1.1 1 0 0 1 1 1 0 Presenilin eIF-5_eIF-2B PF01873.17 EWM28016.1 - 1.9e-34 118.1 0.0 3.9e-34 117.0 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 EWM28016.1 - 1.3e-16 60.5 0.7 1.3e-16 60.5 0.7 3.1 3 0 0 3 3 2 1 eIF4-gamma/eIF5/eIF2-epsilon Zn_Tnp_IS1595 PF12760.7 EWM28016.1 - 0.0073 16.3 0.9 0.015 15.3 0.9 1.5 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DUF1682 PF07946.14 EWM28016.1 - 0.022 14.0 17.9 0.035 13.3 17.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Rrn6 PF10214.9 EWM28016.1 - 0.023 13.2 0.5 0.03 12.8 0.5 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DDHD PF02862.17 EWM28016.1 - 0.13 12.4 2.3 0.24 11.6 2.3 1.5 1 0 0 1 1 1 0 DDHD domain Apt1 PF10351.9 EWM28016.1 - 0.15 10.9 9.5 0.2 10.4 9.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC27 PF09507.10 EWM28016.1 - 0.38 10.1 34.4 0.66 9.3 34.4 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TFIIF_alpha PF05793.12 EWM28016.1 - 0.95 8.0 44.4 1.8 7.1 44.4 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Med19 PF10278.9 EWM28016.1 - 1.5 8.7 36.7 0.81 9.6 34.8 1.5 1 1 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 SAPS PF04499.15 EWM28016.1 - 6.1 5.5 9.7 9.4 4.9 9.7 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.16 EWM28016.1 - 8.5 6.4 9.0 16 5.5 9.0 1.5 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GDP_Man_Dehyd PF16363.5 EWM28017.1 - 7.5e-67 226.1 0.0 9e-67 225.8 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EWM28017.1 - 1.1e-57 195.3 0.0 1.4e-57 194.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EWM28017.1 - 5.4e-22 78.3 0.0 8.2e-15 54.7 0.0 2.0 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EWM28017.1 - 4.6e-20 71.8 0.0 7.4e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EWM28017.1 - 5.4e-17 61.8 0.2 3.5e-15 55.9 0.1 2.8 1 1 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 EWM28017.1 - 1.3e-13 50.7 0.0 1.7e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EWM28017.1 - 0.011 15.7 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding DUF2431 PF10354.9 EWM28020.1 - 3.5e-27 95.7 0.0 6.1e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Peptidase_S10 PF00450.22 EWM28021.1 - 3.9e-97 326.3 0.0 4.9e-97 326.0 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase fn3 PF00041.21 EWM28021.1 - 0.029 14.7 0.0 0.059 13.7 0.0 1.5 1 0 0 1 1 1 0 Fibronectin type III domain NMN_transporter PF04973.12 EWM28022.1 - 0.024 14.6 0.1 0.033 14.2 0.1 1.1 1 0 0 1 1 1 0 Nicotinamide mononucleotide transporter Wzz PF02706.15 EWM28022.1 - 0.3 11.4 2.4 0.37 11.1 1.3 1.7 1 1 1 2 2 2 0 Chain length determinant protein zf-RING_UBOX PF13445.6 EWM28023.1 - 1.6e-06 28.1 9.8 1.6e-06 28.1 9.8 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EWM28023.1 - 3.4e-05 23.6 7.4 3.4e-05 23.6 7.4 3.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EWM28023.1 - 0.00016 21.5 13.7 0.00048 19.9 13.7 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF_2 PF15965.5 EWM28023.1 - 0.00039 20.8 4.5 0.00039 20.8 4.5 2.0 1 1 1 2 2 1 1 TRAF-like zinc-finger zf-C3HC4_4 PF15227.6 EWM28023.1 - 0.00054 20.1 8.8 0.00054 20.1 8.8 2.2 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 EWM28023.1 - 0.0019 18.5 14.3 0.0019 18.5 14.3 2.7 2 1 0 2 2 2 1 Ring finger domain zf-Nse PF11789.8 EWM28023.1 - 0.0043 16.8 5.3 0.013 15.3 5.3 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.6 EWM28023.1 - 0.011 15.6 17.6 0.013 15.5 13.9 2.4 1 1 1 2 2 2 0 zinc-RING finger domain zf-TRAF PF02176.18 EWM28023.1 - 0.027 15.1 1.4 0.027 15.1 1.4 2.8 2 1 1 3 3 2 0 TRAF-type zinc finger Drc1-Sld2 PF11719.8 EWM28023.1 - 0.32 10.5 11.7 0.53 9.8 11.7 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein Nop14 PF04147.12 EWM28023.1 - 0.49 8.5 41.8 0.71 8.0 41.8 1.1 1 0 0 1 1 1 0 Nop14-like family zf-C3HC4_3 PF13920.6 EWM28023.1 - 1.1 9.1 13.4 7.6 6.5 13.4 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Lin-8 PF03353.15 EWM28023.1 - 1.5 8.3 11.2 2.4 7.6 11.2 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SDA1 PF05285.12 EWM28023.1 - 3.9 6.8 40.5 7.2 5.9 40.5 1.3 1 0 0 1 1 1 0 SDA1 Sina PF03145.16 EWM28023.1 - 8.4 6.3 11.7 0.03 14.3 2.3 1.6 2 0 0 2 2 1 0 Seven in absentia protein family AAA_2 PF07724.14 EWM28024.1 - 4.6e-40 137.5 0.0 8.1e-40 136.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 EWM28024.1 - 5.1e-13 49.6 0.0 1e-12 48.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EWM28024.1 - 7.6e-12 45.1 0.1 1.5e-11 44.2 0.1 1.4 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein MCM PF00493.23 EWM28024.1 - 3.8e-06 26.2 0.1 6.5e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain AAA_22 PF13401.6 EWM28024.1 - 1.5e-05 25.3 0.2 0.00011 22.4 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EWM28024.1 - 7.9e-05 22.7 0.1 0.00024 21.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EWM28024.1 - 0.00026 20.4 0.0 0.0052 16.2 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EWM28024.1 - 0.00033 20.4 0.1 0.008 15.9 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.6 EWM28024.1 - 0.0004 20.9 0.0 0.0009 19.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EWM28024.1 - 0.0005 19.8 0.1 0.0021 17.8 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activ_2 PF14532.6 EWM28024.1 - 0.0024 18.0 0.0 0.0096 16.0 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain ABC_tran PF00005.27 EWM28024.1 - 0.0029 18.1 0.0 0.0062 17.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EWM28024.1 - 0.0047 17.3 0.1 0.02 15.2 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 EWM28024.1 - 0.014 15.4 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EWM28024.1 - 0.015 15.1 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein T2SSE PF00437.20 EWM28024.1 - 0.015 14.3 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein zf-FPG_IleRS PF06827.14 EWM28024.1 - 0.023 14.6 0.2 0.059 13.2 0.2 1.8 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS Cys_rich_CPXG PF14255.6 EWM28024.1 - 0.05 13.5 0.4 0.11 12.4 0.4 1.5 1 0 0 1 1 1 0 Cysteine-rich CPXCG TsaE PF02367.17 EWM28024.1 - 0.053 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EWM28024.1 - 0.062 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 EWM28024.1 - 0.062 13.4 0.0 0.17 12.0 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 EWM28024.1 - 0.069 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EWM28024.1 - 0.072 13.0 0.1 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.6 EWM28024.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 EWM28024.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system PhoH PF02562.16 EWM28024.1 - 0.14 11.6 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Abhydrolase_6 PF12697.7 EWM28025.1 - 0.0077 16.8 0.3 0.014 16.0 0.3 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EWM28025.1 - 0.028 14.5 0.0 0.05 13.7 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.25 EWM28025.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase2 PF12740.7 EWM28025.1 - 0.2 10.6 0.3 0.94 8.3 0.0 2.2 3 0 0 3 3 3 0 Chlorophyllase enzyme TMEM223 PF14640.6 EWM28026.1 - 3.9e-09 36.9 0.2 0.0005 20.3 0.0 2.4 2 0 0 2 2 2 2 Transmembrane protein 223 ATP-synt PF00231.19 EWM28027.1 - 3.9e-78 263.0 0.1 4.4e-78 262.8 0.1 1.0 1 0 0 1 1 1 1 ATP synthase Tfb2 PF03849.14 EWM28029.1 - 8.7e-57 192.7 0.0 1.3e-56 192.1 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Rieske PF00355.26 EWM28030.1 - 2e-17 62.9 0.0 6.6e-17 61.2 0.0 1.8 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain PAP_fibrillin PF04755.12 EWM28030.1 - 3.4e-13 50.0 0.0 1.3e-08 35.1 0.0 2.9 2 1 0 2 2 2 2 PAP_fibrillin Rieske_2 PF13806.6 EWM28030.1 - 4.4e-06 26.6 0.0 9.1e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain FYVE PF01363.21 EWM28032.1 - 2.3e-15 56.5 3.5 3.9e-15 55.7 3.5 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 EWM28032.1 - 0.019 15.2 1.2 0.035 14.3 1.2 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Epimerase PF01370.21 EWM28034.1 - 1.1e-23 84.0 0.0 1.6e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EWM28034.1 - 4.1e-22 78.5 0.0 5.5e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EWM28034.1 - 1.5e-13 50.9 0.0 1.8e-12 47.3 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EWM28034.1 - 4.5e-13 49.5 0.0 1e-12 48.3 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EWM28034.1 - 7.6e-13 48.5 0.0 1.4e-10 41.1 0.0 2.3 2 0 0 2 2 2 2 NmrA-like family NAD_binding_4 PF07993.12 EWM28034.1 - 4.3e-11 42.5 0.0 1.2e-10 41.1 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 EWM28034.1 - 0.00019 21.4 0.0 0.00054 19.9 0.0 1.7 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 EWM28034.1 - 0.0014 18.1 0.0 0.0039 16.7 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 EWM28034.1 - 0.0068 15.6 0.0 0.015 14.4 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NEMP PF10225.9 EWM28036.1 - 6.4e-10 39.1 1.6 2.3e-09 37.3 1.6 1.8 1 1 0 1 1 1 1 NEMP family DUF3433 PF11915.8 EWM28036.1 - 0.024 15.1 0.5 0.024 15.1 0.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3433) Arv1 PF04161.13 EWM28037.1 - 7.6e-37 127.5 2.1 2.1e-36 126.1 1.2 1.8 2 0 0 2 2 2 1 Arv1-like family SIR2 PF02146.17 EWM28037.1 - 0.18 11.7 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 Sir2 family CN_hydrolase PF00795.22 EWM28040.1 - 1.4e-63 214.6 0.0 1.8e-63 214.4 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase RAG1 PF12940.7 EWM28040.1 - 0.011 13.8 0.0 0.016 13.4 0.0 1.1 1 0 0 1 1 1 0 Recombination-activation protein 1 (RAG1), recombinase CBFD_NFYB_HMF PF00808.23 EWM28041.1 - 2.9e-28 97.9 0.3 4.1e-28 97.5 0.3 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EWM28041.1 - 0.00039 20.8 0.1 0.00087 19.7 0.1 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EWM28041.1 - 0.0026 17.9 0.0 0.0039 17.3 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 EWM28041.1 - 0.075 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID-18kDa PF02269.16 EWM28041.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Fe-ADH PF00465.19 EWM28042.1 - 1.5e-35 122.7 0.2 1.7e-35 122.5 0.2 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EWM28042.1 - 1.8e-05 24.6 0.0 0.0002 21.2 0.0 2.0 1 1 1 2 2 2 1 Iron-containing alcohol dehydrogenase adh_short PF00106.25 EWM28043.1 - 5.3e-27 94.5 0.0 2.5e-19 69.5 0.1 3.0 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EWM28043.1 - 2.7e-15 56.6 0.0 2e-12 47.2 0.0 3.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM28043.1 - 0.00045 20.2 0.0 0.00064 19.7 0.0 1.2 1 0 0 1 1 1 1 KR domain RRM_1 PF00076.22 EWM28044.1 - 9.9e-05 22.1 0.0 0.00017 21.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4407 PF14362.6 EWM28044.1 - 0.034 13.5 1.8 0.051 12.9 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) XS PF03468.14 EWM28044.1 - 0.081 13.2 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 XS domain GRP PF07172.11 EWM28044.1 - 0.41 11.4 15.4 2.2 9.0 7.2 2.6 3 0 0 3 3 3 0 Glycine rich protein family PRP38 PF03371.15 EWM28045.1 - 4.2e-52 176.5 0.0 5.4e-52 176.2 0.0 1.1 1 0 0 1 1 1 1 PRP38 family YjeF_N PF03853.15 EWM28046.1 - 4.6e-42 143.8 0.0 6.5e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus CutA1 PF03091.15 EWM28046.1 - 2.7e-34 117.0 0.0 4.5e-34 116.3 0.0 1.4 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein TBP PF00352.21 EWM28047.1 - 1.1e-59 198.4 0.0 1e-30 105.5 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EWM28047.1 - 0.0074 16.4 0.0 0.75 10.0 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) XPG_N PF00752.17 EWM28048.1 - 3.8e-29 101.1 0.0 9e-29 99.9 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EWM28048.1 - 9.9e-25 86.7 0.0 2.3e-24 85.6 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 EWM28048.1 - 0.0032 17.0 0.1 0.0069 15.9 0.1 1.5 1 0 0 1 1 1 1 XPG domain containing Ribosomal_60s PF00428.19 EWM28048.1 - 0.051 14.2 4.5 0.23 12.1 4.5 2.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein Methyltr_RsmB-F PF01189.17 EWM28049.1 - 3.4e-22 79.1 0.0 5.8e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F NusB PF01029.18 EWM28049.1 - 2.5e-14 53.6 0.0 4.5e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 NusB family DUF4936 PF16290.5 EWM28050.1 - 0.078 13.7 0.2 0.39 11.4 0.1 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4936) Zn_clus PF00172.18 EWM28051.1 - 2.7e-07 30.6 12.0 5.8e-07 29.5 12.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ER PF01133.17 EWM28052.1 - 4e-36 123.0 0.2 4.4e-36 122.8 0.2 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary Thioredoxin PF00085.20 EWM28053.1 - 3e-23 81.8 0.0 4.4e-23 81.2 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EWM28053.1 - 1.9e-05 24.9 0.0 2.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 EWM28053.1 - 3.1e-05 23.5 0.0 3.9e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 EWM28053.1 - 0.00022 21.0 0.0 0.00028 20.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EWM28053.1 - 0.00024 21.5 0.1 0.0014 19.1 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 EWM28053.1 - 0.00033 20.6 0.1 0.00045 20.1 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA family Glutaredoxin PF00462.24 EWM28053.1 - 0.00054 20.1 0.0 0.00096 19.3 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Redoxin PF08534.10 EWM28053.1 - 0.00065 19.4 0.3 0.0022 17.7 0.2 1.8 1 1 1 2 2 2 1 Redoxin DUF953 PF06110.11 EWM28053.1 - 0.0043 16.7 0.1 0.0063 16.1 0.1 1.4 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Phosducin PF02114.16 EWM28053.1 - 0.0078 15.2 0.0 0.0095 14.9 0.0 1.2 1 0 0 1 1 1 1 Phosducin Thioredoxin_7 PF13899.6 EWM28053.1 - 0.059 13.6 0.1 0.15 12.3 0.1 1.8 1 1 0 1 1 1 0 Thioredoxin-like HyaE PF07449.11 EWM28053.1 - 0.092 12.7 0.1 0.9 9.5 0.0 2.0 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE PseudoU_synth_1 PF01416.20 EWM28056.1 - 3.9e-33 114.2 0.0 1.8e-24 86.3 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase LTD PF00932.19 EWM28057.1 - 2.5e-08 34.2 0.0 4.5e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Lamin Tail Domain GAS PF13851.6 EWM28057.1 - 2.8e-07 30.1 69.0 0.0013 18.1 6.7 4.3 2 2 1 4 4 4 3 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 EWM28057.1 - 5e-05 23.3 71.2 0.00032 20.7 7.7 6.7 3 1 3 6 6 6 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF948 PF06103.11 EWM28057.1 - 0.0018 18.5 16.4 2.9 8.2 0.1 5.5 4 1 0 4 4 4 2 Bacterial protein of unknown function (DUF948) Rootletin PF15035.6 EWM28057.1 - 0.0033 17.5 20.3 0.0033 17.5 20.3 5.1 3 1 1 5 5 5 1 Ciliary rootlet component, centrosome cohesion Phage_GP20 PF06810.11 EWM28057.1 - 0.013 15.4 47.4 0.047 13.5 7.1 5.4 3 1 3 6 6 6 0 Phage minor structural protein GP20 BORCS8 PF10167.9 EWM28057.1 - 0.034 14.1 4.7 0.68 9.9 0.1 3.4 3 0 0 3 3 3 0 BLOC-1-related complex sub-unit 8 NPV_P10 PF05531.12 EWM28057.1 - 0.035 14.6 19.4 0.19 12.2 0.8 5.7 5 1 0 5 5 5 0 Nucleopolyhedrovirus P10 protein TSC22 PF01166.18 EWM28057.1 - 0.042 14.1 1.3 0.042 14.1 1.3 9.2 6 3 4 10 10 10 0 TSC-22/dip/bun family FlaC_arch PF05377.11 EWM28057.1 - 0.044 14.2 40.6 0.44 11.0 0.9 8.6 6 3 2 8 8 8 0 Flagella accessory protein C (FlaC) Bap31_Bap29_C PF18035.1 EWM28057.1 - 0.05 13.6 0.0 0.05 13.6 0.0 5.7 4 2 1 5 5 5 0 Bap31/Bap29 cytoplasmic coiled-coil domain HALZ PF02183.18 EWM28057.1 - 0.055 13.7 50.8 0.45 10.8 2.0 8.7 8 1 0 8 8 8 0 Homeobox associated leucine zipper KASH_CCD PF14662.6 EWM28057.1 - 0.082 12.7 72.9 0.11 12.3 8.1 6.2 2 1 4 6 6 6 0 Coiled-coil region of CCDC155 or KASH TPR_MLP1_2 PF07926.12 EWM28057.1 - 0.094 12.8 72.2 0.27 11.3 1.4 6.5 4 1 1 5 5 5 0 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 EWM28057.1 - 0.66 10.5 82.3 26 5.4 7.5 5.8 1 1 2 3 3 2 0 Apg6 coiled-coil region Fez1 PF06818.15 EWM28057.1 - 0.66 10.4 67.5 0.63 10.5 17.0 4.2 2 1 1 3 3 3 0 Fez1 DASH_Dam1 PF08653.10 EWM28057.1 - 0.74 9.7 18.2 0.16 11.8 0.2 6.0 7 1 1 8 8 6 0 DASH complex subunit Dam1 Baculo_PEP_C PF04513.12 EWM28057.1 - 0.94 9.5 18.7 8.3 6.5 0.3 4.6 3 2 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 EWM28057.1 - 1.3 9.1 35.0 2.3 8.3 4.9 5.5 2 1 2 5 5 5 0 Protein of unknown function (DUF1664) CALCOCO1 PF07888.11 EWM28057.1 - 2.1 7.1 72.6 5.5 5.8 36.4 2.7 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like bZIP_1 PF00170.21 EWM28057.1 - 2.1 8.5 70.4 1.7 8.8 3.8 10.5 6 3 4 10 10 10 0 bZIP transcription factor YabA PF06156.13 EWM28057.1 - 2.3 8.9 58.8 0.25 12.0 2.3 7.7 2 1 4 6 6 6 0 Initiation control protein YabA FH2 PF02181.23 EWM28057.1 - 2.8 7.0 37.9 1.9 7.5 1.4 4.4 2 1 1 4 4 4 0 Formin Homology 2 Domain DUF4407 PF14362.6 EWM28057.1 - 3.5 6.9 52.7 0.09 12.1 12.0 3.6 1 1 1 2 2 1 0 Domain of unknown function (DUF4407) COG5 PF10392.9 EWM28057.1 - 6.8 6.9 23.7 1.7 8.8 0.2 5.0 2 2 3 5 5 5 0 Golgi transport complex subunit 5 AAA_13 PF13166.6 EWM28057.1 - 7.9 5.0 46.2 0.1 11.3 17.2 2.6 1 1 1 2 2 2 0 AAA domain MatP_C PF17414.2 EWM28057.1 - 8.7 6.6 7.3 46 4.3 0.8 3.5 2 1 0 2 2 2 0 MatP C-terminal ribbon-helix-helix domain MFS_1 PF07690.16 EWM28058.1 - 2.9e-27 95.5 38.0 1.5e-25 89.9 16.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CRM1_C PF08767.11 EWM28059.1 - 5.4e-112 374.1 1.2 1.1e-111 373.1 0.1 2.1 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 EWM28059.1 - 2.7e-36 124.9 5.5 1.3e-35 122.7 5.5 2.3 1 0 0 1 1 1 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 EWM28059.1 - 5.2e-33 112.5 1.7 2.4e-32 110.4 1.7 2.3 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 EWM28059.1 - 4.8e-31 106.6 1.0 3.9e-30 103.7 1.0 2.4 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 EWM28059.1 - 1.3e-18 66.2 0.3 2.8e-18 65.1 0.3 1.6 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 EWM28059.1 - 2.1e-10 40.3 0.6 1.1e-09 38.0 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF4543 PF15076.6 EWM28059.1 - 0.11 12.7 0.1 0.35 11.0 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4543) DUF3638 PF12340.8 EWM28060.1 - 2.7e-29 102.1 0.1 1.4e-28 99.8 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 EWM28060.1 - 2.9e-15 55.4 0.1 7.6e-15 54.0 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Thioredoxin_8 PF13905.6 EWM28060.1 - 1.2e-11 44.8 0.0 3.2e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like EF-hand_7 PF13499.6 EWM28060.1 - 1.1e-07 32.2 0.1 5.5e-07 29.9 0.1 2.3 1 0 0 1 1 1 1 EF-hand domain pair zf-RanBP PF00641.18 EWM28060.1 - 3.2e-05 23.2 2.4 3.2e-05 23.2 2.4 3.8 4 0 0 4 4 4 2 Zn-finger in Ran binding protein and others EF-hand_1 PF00036.32 EWM28060.1 - 0.00016 21.0 0.0 0.015 14.8 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EWM28060.1 - 0.0002 21.1 0.1 0.0032 17.3 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 EWM28060.1 - 0.0024 17.7 0.2 0.076 12.9 0.1 2.6 1 1 1 2 2 2 2 EF-hand domain pair UBA PF00627.31 EWM28060.1 - 0.011 15.6 0.3 0.011 15.6 0.3 2.8 3 0 0 3 3 3 0 UBA/TS-N domain EF-hand_5 PF13202.6 EWM28060.1 - 0.021 14.3 0.0 0.075 12.6 0.0 2.0 1 0 0 1 1 1 0 EF hand Glyco_transf_92 PF01697.27 EWM28062.1 - 2.6e-13 50.3 0.1 4.9e-13 49.3 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 EWM28062.1 - 1.2e-09 38.6 0.0 2.9e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glycos_transf_2 PF00535.26 EWM28062.1 - 0.016 15.0 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 EWM28063.1 - 2.6e-13 50.3 0.1 4.9e-13 49.3 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 EWM28063.1 - 1.2e-09 38.6 0.0 2.9e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glycos_transf_2 PF00535.26 EWM28063.1 - 0.016 15.0 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 IQ PF00612.27 EWM28065.1 - 1.6e-20 70.9 192.7 0.00075 19.1 0.9 25.8 23 2 2 25 25 25 21 IQ calmodulin-binding motif CH PF00307.31 EWM28065.1 - 5e-05 23.4 0.3 0.017 15.3 0.0 3.3 2 1 0 2 2 2 1 Calponin homology (CH) domain Ribosomal_S8 PF00410.19 EWM28066.1 - 2.7e-20 72.6 0.0 3.6e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 adh_short PF00106.25 EWM28067.1 - 3.6e-44 150.6 0.0 4.9e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EWM28067.1 - 2.2e-22 79.7 0.0 2.9e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM28067.1 - 4.2e-07 30.0 0.0 1.4e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 KR domain Glyco_transf_5 PF08323.11 EWM28067.1 - 0.023 14.4 0.0 0.19 11.4 0.0 2.0 2 0 0 2 2 2 0 Starch synthase catalytic domain Epimerase PF01370.21 EWM28067.1 - 0.036 13.5 0.0 0.28 10.6 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 EWM28067.1 - 0.083 12.3 0.0 0.41 10.0 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EWM28067.1 - 0.12 13.0 0.0 0.35 11.5 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 EWM28067.1 - 0.18 10.9 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein COesterase PF00135.28 EWM28068.1 - 2.1e-106 356.9 0.0 3.6e-106 356.1 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EWM28068.1 - 0.00039 20.3 0.3 0.0016 18.3 0.4 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EWM28068.1 - 0.041 13.4 0.6 0.074 12.5 0.6 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Rad4 PF03835.15 EWM28069.1 - 3.6e-11 43.0 0.0 6.5e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain PUB PF09409.10 EWM28069.1 - 6.3e-10 38.9 0.0 1.6e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 PUB domain Transglut_core PF01841.19 EWM28069.1 - 4.3e-09 36.8 0.2 9.1e-09 35.8 0.2 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily TBK1_ULD PF18396.1 EWM28069.1 - 0.041 13.8 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain BTK PF00779.19 EWM28070.1 - 0.0051 16.6 3.9 0.24 11.2 1.3 2.5 2 0 0 2 2 2 2 BTK motif MNNL PF07657.13 EWM28070.1 - 0.13 12.3 3.9 0.19 11.8 0.1 2.3 1 1 1 2 2 2 0 N terminus of Notch ligand CHORD PF04968.12 EWM28070.1 - 0.17 12.7 8.9 3.5 8.4 8.9 2.6 1 1 0 1 1 1 0 CHORD ubiquitin PF00240.23 EWM28075.1 - 4.2e-28 96.9 0.1 5.4e-28 96.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EWM28075.1 - 9.2e-14 51.0 0.2 1.2e-13 50.7 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EWM28075.1 - 0.002 18.5 0.1 0.008 16.6 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 EWM28075.1 - 0.017 15.2 0.2 1.1 9.4 0.1 2.1 2 0 0 2 2 2 0 Ubiquitin-like domain TBK1_ULD PF18396.1 EWM28075.1 - 0.027 14.4 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain RBD PF02196.15 EWM28075.1 - 0.11 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Raf-like Ras-binding domain Ubiquitin_5 PF18037.1 EWM28075.1 - 0.11 12.8 0.0 0.19 12.1 0.0 1.4 1 1 0 1 1 1 0 Ubiquitin-like domain Thioredoxin PF00085.20 EWM28076.1 - 1.3e-19 70.1 0.0 2.6e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin PUB PF09409.10 EWM28076.1 - 1.2e-16 60.4 0.0 2.3e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 PUB domain UBA PF00627.31 EWM28076.1 - 7.8e-06 25.7 0.0 0.00021 21.1 0.0 2.9 2 0 0 2 2 2 1 UBA/TS-N domain AhpC-TSA PF00578.21 EWM28076.1 - 0.0058 16.6 0.0 0.046 13.6 0.0 2.2 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_7 PF13899.6 EWM28076.1 - 0.021 15.0 0.1 0.083 13.1 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like XRN_N PF03159.18 EWM28076.1 - 0.021 14.3 0.0 0.047 13.1 0.0 1.5 1 1 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus Thioredoxin_9 PF14595.6 EWM28076.1 - 0.024 14.4 0.0 0.024 14.4 0.0 2.0 2 1 0 2 2 2 0 Thioredoxin Thioredoxin_8 PF13905.6 EWM28076.1 - 0.13 12.6 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.6 EWM28076.1 - 0.16 12.4 0.4 0.9 10.0 0.0 2.4 2 1 0 2 2 2 0 Thioredoxin-like domain DUF874 PF05917.11 EWM28076.1 - 0.19 10.7 5.3 0.29 10.1 5.3 1.1 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) OST3_OST6 PF04756.13 EWM28076.1 - 0.26 10.6 0.0 0.41 9.9 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family zf-RING_2 PF13639.6 EWM28077.1 - 2.4e-06 27.8 9.8 7.3e-06 26.2 9.8 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EWM28077.1 - 2.9e-06 26.9 2.5 7.2e-06 25.6 2.5 1.7 1 0 0 1 1 1 1 RING-like zinc finger FANCL_C PF11793.8 EWM28077.1 - 0.00099 19.2 3.8 0.0021 18.2 3.8 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 EWM28077.1 - 0.22 11.8 9.8 1 9.7 9.8 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EWM28077.1 - 0.32 10.9 5.6 0.75 9.7 5.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EWM28077.1 - 0.72 9.7 8.7 4.2 7.3 8.7 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EWM28077.1 - 1.9 8.2 8.6 7.7 6.2 8.6 2.0 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type SirA PF10747.9 EWM28079.1 - 1.4 9.2 5.0 0.44 10.9 0.1 2.4 2 0 0 2 2 2 0 Sporulation inhibitor of replication protein SirA AMP-binding PF00501.28 EWM28080.1 - 4.1e-74 249.7 0.0 6e-74 249.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EWM28080.1 - 0.0023 18.8 0.1 0.0072 17.3 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 EWM28081.1 - 3.9e-74 249.8 0.0 5.5e-74 249.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EWM28081.1 - 0.0021 19.0 0.1 0.007 17.3 0.1 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SET PF00856.28 EWM28082.1 - 0.00099 19.5 0.0 0.0047 17.3 0.0 2.3 1 1 0 1 1 1 1 SET domain RNA_pol_Rpb8 PF03870.15 EWM28083.1 - 3.8e-38 130.8 0.0 4.9e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 EWM28083.1 - 0.0038 17.3 0.1 1.8 8.7 0.0 2.4 2 1 0 2 2 2 2 DNA-directed RNA polymerase, subunit G DndB PF14072.6 EWM28085.1 - 0.00018 20.8 0.1 0.0014 18.0 0.0 2.0 2 0 0 2 2 2 1 DNA-sulfur modification-associated DUF262 PF03235.14 EWM28085.1 - 0.011 15.9 0.0 0.015 15.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 AstE_AspA PF04952.14 EWM28085.1 - 0.18 10.8 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family SGS PF05002.15 EWM28086.1 - 1.3e-29 102.1 3.9 2.6e-29 101.1 3.9 1.5 1 0 0 1 1 1 1 SGS domain CS PF04969.16 EWM28086.1 - 1e-14 55.3 0.0 2.1e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 CS domain TPR_1 PF00515.28 EWM28086.1 - 1.2e-06 28.1 0.1 0.022 14.6 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EWM28086.1 - 2.6e-06 27.1 3.7 0.019 15.1 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EWM28086.1 - 0.003 18.2 12.2 0.047 14.3 5.1 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EWM28086.1 - 0.0062 17.1 4.1 1.8 9.3 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EWM28086.1 - 0.011 16.2 1.3 0.052 14.1 0.1 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EWM28086.1 - 0.024 14.8 0.1 0.9 9.9 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 EWM28086.1 - 0.046 13.9 4.0 0.064 13.4 1.2 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EWM28086.1 - 0.064 13.5 0.6 0.12 12.6 0.6 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EWM28086.1 - 0.089 13.2 0.2 0.35 11.3 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EWM28086.1 - 0.16 12.3 1.9 0.53 10.6 0.3 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EWM28086.1 - 0.25 12.3 10.7 0.6 11.1 0.5 3.7 2 1 2 4 4 3 0 Tetratricopeptide repeat Pyrid_oxidase_2 PF13883.6 EWM28087.1 - 3.1e-24 85.8 0.0 4.5e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF2470 PF10615.9 EWM28087.1 - 2.6e-12 47.2 0.1 4.5e-12 46.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Putative_PNPOx PF01243.20 EWM28087.1 - 6.4e-06 26.3 0.0 1.3e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF2070 PF09843.9 EWM28088.1 - 0.027 12.8 1.0 0.031 12.6 1.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF5319 PF17252.2 EWM28088.1 - 0.068 13.4 0.1 0.17 12.1 0.1 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5319) 7tm_6 PF02949.20 EWM28088.1 - 0.24 10.4 5.4 0.096 11.7 2.1 1.9 1 1 1 2 2 2 0 7tm Odorant receptor DUF2207 PF09972.9 EWM28088.1 - 2.7 6.7 4.2 1.2 7.8 0.0 1.9 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) SET PF00856.28 EWM28089.1 - 1.1e-09 39.0 0.0 2.5e-09 37.7 0.0 1.8 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.18 EWM28089.1 - 0.0029 17.7 9.5 0.0029 17.7 9.5 3.2 4 0 0 4 4 4 1 MYND finger EXS PF03124.14 EWM28090.1 - 7.3e-66 222.7 2.9 8.8e-66 222.5 2.9 1.0 1 0 0 1 1 1 1 EXS family LSM PF01423.22 EWM28091.1 - 3.4e-19 68.3 0.0 3.9e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EWM28091.1 - 0.0071 16.5 0.0 0.0089 16.1 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain PPR PF01535.20 EWM28093.1 - 1.5e-21 75.1 0.2 0.0032 17.6 0.0 7.0 8 0 0 8 8 8 5 PPR repeat PPR_2 PF13041.6 EWM28093.1 - 3.8e-21 75.0 0.0 2.7e-07 30.7 0.0 6.1 4 1 3 7 7 7 5 PPR repeat family PPR_3 PF13812.6 EWM28093.1 - 3.3e-14 52.7 0.0 1e-05 25.5 0.0 5.4 4 2 0 5 5 5 2 Pentatricopeptide repeat domain PPR_long PF17177.4 EWM28093.1 - 2.3e-13 50.0 0.0 6.7e-08 32.1 0.0 3.1 1 1 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EWM28093.1 - 1.3e-10 40.8 0.0 0.04 13.6 0.0 5.5 6 0 0 6 6 6 4 PPR repeat TPR_14 PF13428.6 EWM28093.1 - 0.0063 17.2 9.8 3.6 8.6 0.2 5.9 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 EWM28093.1 - 0.0077 16.2 0.1 8.4 6.7 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 EWM28093.1 - 0.0083 16.7 3.9 2.3 9.1 0.3 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EWM28093.1 - 0.033 13.8 0.4 1.1 9.0 0.0 2.9 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_6 PF13174.6 EWM28093.1 - 0.63 10.8 2.5 38 5.2 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Na_H_Exchanger PF00999.21 EWM28094.1 - 4.9e-35 121.0 41.7 7.3e-35 120.5 41.7 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family THOC7 PF05615.13 EWM28094.1 - 0.0046 17.2 2.4 0.0099 16.2 2.4 1.6 1 0 0 1 1 1 1 Tho complex subunit 7 Prefoldin_2 PF01920.20 EWM28094.1 - 0.011 15.7 1.9 0.026 14.5 1.9 1.6 1 0 0 1 1 1 0 Prefoldin subunit Atg14 PF10186.9 EWM28094.1 - 0.057 12.5 4.2 1.2 8.2 4.2 2.1 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2205 PF10224.9 EWM28094.1 - 0.14 12.2 6.7 0.094 12.7 1.4 2.7 2 1 1 3 3 3 0 Short coiled-coil protein DUF1664 PF07889.12 EWM28094.1 - 0.25 11.4 3.6 0.41 10.7 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) VIT1 PF01988.19 EWM28095.1 - 1.1e-55 188.8 0.2 1.4e-55 188.5 0.2 1.1 1 0 0 1 1 1 1 VIT family DNA_pol_A PF00476.20 EWM28096.1 - 1.9e-90 303.6 0.1 3.6e-80 269.8 0.3 2.2 2 0 0 2 2 2 2 DNA polymerase family A Helicase_C PF00271.31 EWM28096.1 - 6.6e-15 55.4 0.1 9.7e-11 42.0 0.0 2.7 1 1 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 EWM28096.1 - 4.8e-14 52.5 0.0 1.7e-13 50.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EWM28096.1 - 3e-05 24.1 0.0 5.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_5 PF14520.6 EWM28096.1 - 0.039 14.6 0.0 0.13 12.9 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain Tubulin PF00091.25 EWM28097.1 - 6.1e-43 147.3 1.5 9.2e-43 146.7 1.5 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain NAD_binding_10 PF13460.6 EWM28097.1 - 0.0022 17.9 0.3 0.0082 16.1 0.3 1.9 1 1 0 1 1 1 1 NAD(P)H-binding Tubulin_2 PF13809.6 EWM28097.1 - 0.015 14.6 8.2 0.47 9.6 5.4 2.7 1 1 1 2 2 2 0 Tubulin like Sulfatase PF00884.23 EWM28099.1 - 8.1e-44 150.2 0.0 1.2e-43 149.7 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EWM28099.1 - 9.5e-05 22.1 1.4 0.003 17.2 1.4 2.6 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 EWM28099.1 - 0.0005 18.8 0.2 0.0012 17.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 EWM28099.1 - 0.0077 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily HSP90 PF00183.18 EWM28100.1 - 1.3e-164 548.9 2.2 8.6e-164 546.2 2.2 1.9 1 1 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.6 EWM28100.1 - 3.1e-11 43.3 0.2 1e-10 41.6 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EWM28100.1 - 2.5e-10 40.8 0.0 6e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Histidinol_dh PF00815.20 EWM28101.1 - 7e-122 407.3 2.5 8.5e-122 407.1 2.5 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase DUF1995 PF09353.10 EWM28102.1 - 9.1e-23 81.3 0.0 1.3e-22 80.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) DUF2470 PF10615.9 EWM28102.1 - 0.0091 16.6 0.0 0.017 15.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) PALP PF00291.25 EWM28104.1 - 1.2e-75 254.7 5.5 1.7e-75 254.2 5.5 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 EWM28104.1 - 2.6e-34 116.8 0.0 1.5e-18 66.4 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase GTP_EFTU PF00009.27 EWM28105.1 - 5.5e-46 156.6 0.1 2.8e-45 154.3 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EWM28105.1 - 6.1e-15 55.0 0.0 1.6e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EWM28105.1 - 8.4e-08 32.5 0.3 2.7e-07 30.9 0.3 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EWM28105.1 - 0.00012 22.2 0.0 0.00037 20.5 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 EWM28105.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Septin EFG_II PF14492.6 EWM28105.1 - 0.11 12.6 0.0 0.43 10.7 0.0 2.0 1 0 0 1 1 1 0 Elongation Factor G, domain II RRM_1 PF00076.22 EWM28106.1 - 2e-52 174.9 0.0 2.1e-19 69.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EWM28106.1 - 2.1e-08 34.2 0.0 0.19 11.9 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif ABC2_membrane PF01061.24 EWM28107.1 - 7.7e-30 103.9 16.9 1.2e-29 103.2 16.9 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EWM28107.1 - 1.4e-17 64.5 0.0 2.1e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EWM28107.1 - 0.00053 19.2 19.8 0.00081 18.6 19.8 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 EWM28107.1 - 0.0036 17.2 0.1 0.006 16.5 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EWM28107.1 - 0.022 15.2 0.1 0.051 13.9 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain Adeno_E1B_55K_N PF04623.12 EWM28107.1 - 0.069 13.9 0.7 61 4.4 0.0 3.4 3 0 0 3 3 3 0 Adenovirus E1B protein N-terminus SMC_N PF02463.19 EWM28107.1 - 0.09 12.2 0.0 13 5.1 0.1 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ABC2_membrane_2 PF12679.7 EWM28107.1 - 1.1 8.5 15.7 6.2 6.0 14.2 2.1 1 1 1 2 2 2 0 ABC-2 family transporter protein Sec1 PF00995.23 EWM28108.1 - 6e-103 346.0 0.0 7.3e-103 345.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family PrmA PF06325.13 EWM28110.1 - 2.6e-42 145.3 0.0 4.2e-42 144.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EWM28110.1 - 9.9e-07 28.5 0.1 3.6e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EWM28110.1 - 1.2e-05 25.1 0.0 2.7e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM28110.1 - 2.5e-05 24.9 0.0 8.4e-05 23.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EWM28110.1 - 0.00097 19.1 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM28110.1 - 0.0042 17.7 0.0 0.012 16.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EWM28110.1 - 0.016 15.0 0.1 0.038 13.8 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 EWM28110.1 - 0.029 14.1 0.0 0.062 13.0 0.0 1.5 1 1 0 1 1 1 0 Met-10+ like-protein PCMT PF01135.19 EWM28110.1 - 0.039 13.7 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.15 EWM28110.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Senescence PF06911.12 EWM28110.1 - 0.17 12.2 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Senescence-associated protein CBM53 PF16760.5 EWM28111.1 - 0.0021 18.6 0.0 0.0038 17.8 0.0 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) zf-RING_UBOX PF13445.6 EWM28114.1 - 6.3e-09 35.7 10.1 7.5e-09 35.5 7.9 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EWM28114.1 - 6.6e-08 32.3 15.4 1.4e-07 31.2 15.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EWM28114.1 - 2.5e-07 30.4 14.9 4.4e-07 29.7 14.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EWM28114.1 - 3.5e-07 30.4 15.2 6.3e-07 29.6 15.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EWM28114.1 - 5.2e-06 26.2 11.7 9.3e-06 25.4 11.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EWM28114.1 - 6.5e-05 23.1 10.5 0.00014 22.1 10.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EWM28114.1 - 0.00039 20.1 5.7 0.0007 19.3 5.7 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 EWM28114.1 - 0.00042 20.2 13.7 0.00042 20.2 13.7 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EWM28114.1 - 0.0029 17.6 6.5 0.0054 16.7 6.5 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 EWM28114.1 - 0.012 15.8 15.0 0.021 15.0 15.0 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 EWM28114.1 - 0.012 15.4 8.5 0.023 14.5 8.5 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 EWM28114.1 - 0.018 15.1 11.3 0.043 14.0 11.3 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 EWM28114.1 - 0.083 12.8 13.0 0.17 11.8 13.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Ribosomal_S9 PF00380.19 EWM28115.1 - 5.4e-45 152.8 0.1 1.4e-44 151.5 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S9/S16 tRNA_synt_1c_R2 PF04557.15 EWM28116.1 - 0.24 12.3 1.8 0.3 12.0 0.2 2.0 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 NinE PF05322.11 EWM28116.1 - 0.44 10.5 1.9 3.8 7.5 0.1 2.6 3 0 0 3 3 3 0 NINE Protein 5_3_exonuc_N PF02739.16 EWM28117.1 - 7.5e-28 97.4 0.0 1.1e-27 96.9 0.0 1.2 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 EWM28117.1 - 5.1e-22 78.3 0.0 1e-21 77.3 0.0 1.4 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 EWM28117.1 - 0.00024 21.6 0.0 0.00062 20.3 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 EWM28117.1 - 0.00097 19.2 0.0 0.0023 18.0 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPRY PF00622.28 EWM28118.1 - 0.0003 20.9 0.1 0.00077 19.6 0.0 1.6 2 0 0 2 2 2 1 SPRY domain Foie-gras_1 PF11817.8 EWM28119.1 - 1.7e-07 31.1 0.3 3.2e-07 30.2 0.3 1.4 1 0 0 1 1 1 1 Foie gras liver health family 1 TRAPPC10 PF12584.8 EWM28119.1 - 0.00027 20.7 0.0 0.00064 19.5 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 TPR_14 PF13428.6 EWM28119.1 - 0.06 14.2 0.9 0.9 10.5 0.9 3.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 EWM28119.1 - 0.099 12.9 4.3 0.06 13.6 0.9 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 EWM28119.1 - 1.5 9.6 6.7 1.6 9.5 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EWM28119.1 - 1.5 9.1 4.1 1.6 9.0 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat G10 PF01125.17 EWM28120.1 - 0.096 12.5 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 G10 protein RPN7 PF10602.9 EWM28121.1 - 3.2e-41 140.9 0.0 4.9e-41 140.3 0.0 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EWM28121.1 - 1.1e-15 58.0 0.0 2.5e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.17 EWM28121.1 - 0.24 11.6 2.6 3.8 7.8 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat RPN7 PF10602.9 EWM28122.1 - 2.9e-41 141.1 0.0 4.7e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EWM28122.1 - 9.8e-16 58.2 0.0 2.4e-15 56.9 0.0 1.7 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 EWM28122.1 - 0.21 11.8 2.6 3.7 7.9 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TatD_DNase PF01026.21 EWM28123.1 - 2.5e-41 141.7 0.0 3.7e-41 141.2 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase GTP_EFTU PF00009.27 EWM28125.1 - 4.4e-49 166.7 0.0 6.3e-49 166.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 EWM28125.1 - 1.2e-30 106.6 5.4 2.2e-30 105.7 5.4 1.5 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 EWM28125.1 - 7.3e-25 87.1 0.0 1.5e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 EWM28125.1 - 3.9e-24 84.5 0.0 9.5e-24 83.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EWM28125.1 - 8.4e-10 38.9 0.0 2e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EWM28125.1 - 4e-07 30.0 0.0 9.3e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EWM28125.1 - 9.8e-05 22.4 0.0 0.00018 21.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 EWM28125.1 - 0.001 18.4 0.0 0.002 17.5 0.0 1.4 1 1 0 1 1 1 1 Septin Ras PF00071.22 EWM28125.1 - 0.031 13.9 0.0 0.11 12.1 0.0 1.9 1 1 0 1 1 1 0 Ras family Roc PF08477.13 EWM28125.1 - 0.036 14.3 0.0 0.16 12.2 0.0 2.0 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 EWM28125.1 - 0.13 11.9 0.1 4.1 6.9 0.1 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain ABM PF03992.16 EWM28126.1 - 7.1e-05 22.8 0.0 0.0001 22.3 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Pkinase PF00069.25 EWM28127.1 - 2.6e-44 151.6 0.0 5.6e-44 150.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM28127.1 - 5e-23 81.7 0.0 7.6e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EWM28127.1 - 0.00037 20.5 2.1 0.15 12.0 0.0 3.0 2 2 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EWM28127.1 - 0.0035 16.7 0.0 0.0073 15.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EWM28127.1 - 0.01 15.4 0.1 0.038 13.6 0.1 1.8 1 1 1 2 2 2 0 RIO1 family FTA2 PF13095.6 EWM28127.1 - 0.14 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 EWM28127.1 - 0.21 10.6 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 HisG PF01634.18 EWM28128.1 - 1.2e-52 178.1 0.1 1.7e-52 177.6 0.1 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 EWM28128.1 - 5.3e-25 87.4 0.0 9.7e-25 86.5 0.0 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 EWM28128.1 - 0.0011 19.0 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like LysR_substrate PF03466.20 EWM28128.1 - 0.051 12.9 0.0 0.12 11.8 0.0 1.5 1 1 0 1 1 1 0 LysR substrate binding domain LRR_6 PF13516.6 EWM28129.1 - 3.5e-13 48.5 2.4 4e-05 23.3 0.0 4.8 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.33 EWM28129.1 - 0.028 14.9 0.4 2.4 9.0 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich Repeat TTc_toxin_rep PF18807.1 EWM28129.1 - 0.09 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Tripartite Tc toxins repeat LRR_4 PF12799.7 EWM28129.1 - 0.27 11.7 1.8 1.4 9.5 0.1 2.6 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) ETF PF01012.21 EWM28129.1 - 0.29 11.0 3.9 1.4 8.8 0.2 2.6 2 1 0 2 2 2 0 Electron transfer flavoprotein domain TPR_2 PF07719.17 EWM28130.1 - 7.8e-08 31.9 1.8 5.3e-06 26.1 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EWM28130.1 - 8e-08 31.8 1.0 7.7e-07 28.7 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat Methyltransf_28 PF02636.17 EWM28130.1 - 2.6e-06 27.3 0.0 0.039 13.6 0.0 2.1 2 0 0 2 2 2 2 Putative S-adenosyl-L-methionine-dependent methyltransferase TPR_7 PF13176.6 EWM28130.1 - 1.6e-05 24.6 2.5 0.00026 20.8 0.4 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EWM28130.1 - 0.00011 22.4 0.6 0.00035 20.8 0.5 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 EWM28130.1 - 0.0047 17.0 0.2 0.029 14.6 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EWM28130.1 - 0.0065 16.1 0.1 0.04 13.6 0.0 2.3 2 0 0 2 2 2 1 TPR repeat TPR_10 PF13374.6 EWM28130.1 - 0.015 15.2 1.0 0.034 14.0 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EWM28130.1 - 0.017 15.3 0.1 0.041 14.1 0.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EWM28130.1 - 0.077 13.9 0.4 1.7 9.7 0.0 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EWM28130.1 - 0.12 13.1 1.3 1.2 9.9 0.0 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat RepC PF06504.11 EWM28130.1 - 0.13 11.4 0.0 1.3 8.1 0.0 2.0 2 0 0 2 2 2 0 Replication protein C (RepC) SKIP_SNW PF02731.15 EWM28131.1 - 3e-67 225.3 3.2 3e-67 225.3 3.2 1.5 2 0 0 2 2 2 1 SKIP/SNW domain DUF2756 PF10956.8 EWM28131.1 - 0.06 13.9 1.5 9.5 6.8 0.1 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF2756) G6B PF15096.6 EWM28132.1 - 0.0093 15.8 0.1 0.042 13.6 0.0 2.1 2 0 0 2 2 2 1 G6B family NAD_binding_2 PF03446.15 EWM28133.1 - 1.5e-26 93.5 0.1 2.3e-26 92.8 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 EWM28133.1 - 2.7e-07 30.1 0.0 3.8e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_11 PF14833.6 EWM28133.1 - 7.2e-07 29.5 0.3 2.4e-06 27.8 0.3 1.9 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase IlvN PF07991.12 EWM28133.1 - 4e-05 23.3 0.0 7.1e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 EWM28133.1 - 0.00072 20.1 0.0 0.0021 18.6 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 EWM28133.1 - 0.011 15.6 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Mpv17_PMP22 PF04117.12 EWM28134.1 - 1.7e-20 73.0 0.0 3.1e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family RRM_1 PF00076.22 EWM28135.1 - 2.1e-21 75.5 0.0 3.6e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YppG PF14179.6 EWM28135.1 - 0.14 12.9 0.2 0.14 12.9 0.2 4.3 3 1 0 3 3 3 0 YppG-like protein SUIM_assoc PF16619.5 EWM28135.1 - 4.6 7.4 24.8 0.66 10.1 7.7 3.6 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 EWM28135.1 - 7.4 6.4 27.1 0.8 9.6 7.7 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Exo_endo_phos PF03372.23 EWM28136.1 - 1e-09 38.3 0.0 2.1e-09 37.3 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family T2SSM_b PF10741.9 EWM28136.1 - 0.12 12.2 0.1 0.58 10.0 0.0 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b Peptidase_S28 PF05577.12 EWM28137.1 - 2.6e-79 267.1 0.0 3.1e-79 266.8 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 EWM28137.1 - 8.5e-06 25.2 0.0 9.8e-05 21.7 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S37 PF05576.11 EWM28137.1 - 1.1e-05 24.4 0.0 1.9e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 PS-10 peptidase S37 Abhydrolase_1 PF00561.20 EWM28137.1 - 5.2e-05 23.0 0.0 8.5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2920 PF11144.8 EWM28137.1 - 0.05 12.8 0.0 0.087 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Peptidase_S9 PF00326.21 EWM28137.1 - 0.072 12.6 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EWM28137.1 - 0.081 13.5 4.7 0.49 11.0 4.6 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family Glyoxalase_4 PF13669.6 EWM28137.1 - 0.14 12.4 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TPR_2 PF07719.17 EWM28138.1 - 6.3e-05 22.8 6.3 0.81 10.0 0.0 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EWM28138.1 - 0.00061 20.3 0.3 0.099 13.2 0.0 3.7 2 1 1 3 3 2 1 Tetratricopeptide repeat PHD PF00628.29 EWM28138.1 - 0.0051 16.7 12.8 0.014 15.3 12.8 1.8 1 0 0 1 1 1 1 PHD-finger TPR_16 PF13432.6 EWM28138.1 - 0.0056 17.3 12.2 0.023 15.4 0.3 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EWM28138.1 - 0.0073 17.0 16.6 0.021 15.6 0.1 6.3 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EWM28138.1 - 0.022 14.6 1.2 1.5 8.8 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 EWM28138.1 - 0.043 13.2 0.6 0.18 11.1 0.1 2.2 2 0 0 2 2 2 0 MalT-like TPR region ANAPC3 PF12895.7 EWM28138.1 - 0.11 12.7 1.3 22 5.4 0.1 4.0 4 0 0 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 EWM28138.1 - 0.17 11.6 0.0 1.7 8.4 0.0 2.6 2 0 0 2 2 2 0 TPR repeat Lsr2 PF11774.8 EWM28138.1 - 0.42 10.8 1.6 1.5 9.0 1.6 1.9 1 0 0 1 1 1 0 Lsr2 TPR_12 PF13424.6 EWM28138.1 - 0.47 10.8 9.3 6.9 7.0 0.8 4.8 5 1 0 5 5 5 0 Tetratricopeptide repeat Zf_RING PF16744.5 EWM28138.1 - 6.8 6.9 9.8 16 5.7 8.4 2.3 2 0 0 2 2 2 0 KIAA1045 RING finger Vma12 PF11712.8 EWM28139.1 - 4.7e-09 36.4 0.0 6.7e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase RmlD_sub_bind PF04321.17 EWM28140.1 - 0.0021 17.2 0.0 0.0035 16.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EWM28140.1 - 0.0081 15.6 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Adaptin_N PF01602.20 EWM28142.1 - 1.9e-112 376.5 0.0 2.5e-112 376.1 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EWM28142.1 - 5.6e-16 59.0 4.5 1.5e-13 51.1 0.4 2.9 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EWM28142.1 - 1e-05 25.8 0.6 0.034 14.5 0.1 4.4 3 1 1 4 4 4 2 HEAT repeats RTP1_C1 PF10363.9 EWM28142.1 - 0.00015 21.9 1.3 0.45 10.7 0.1 3.9 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 EWM28142.1 - 0.073 13.4 5.4 16 6.1 0.1 5.1 6 0 0 6 6 6 0 HEAT repeat Metallophos PF00149.28 EWM28143.1 - 4.2e-11 43.7 0.0 7.7e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EWM28143.1 - 4.6e-08 33.4 0.0 8.3e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 EWM28143.1 - 0.03 13.6 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Img2 PF05046.14 EWM28143.1 - 0.13 12.6 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) PCI PF01399.27 EWM28145.1 - 1.6e-06 28.6 0.0 2.7e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 PCI domain DUF2859 PF11072.8 EWM28145.1 - 0.042 13.6 0.4 0.095 12.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2859) SlyX PF04102.12 EWM28145.1 - 0.085 13.5 1.9 0.22 12.1 0.0 2.8 3 0 0 3 3 3 0 SlyX TPR_6 PF13174.6 EWM28145.1 - 0.087 13.5 0.0 9.5 7.1 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Paf67 PF10255.9 EWM28145.1 - 0.15 11.0 0.3 0.31 10.0 0.1 1.5 2 0 0 2 2 2 0 RNA polymerase I-associated factor PAF67 RuBisCo_chap_C PF18087.1 EWM28147.1 - 1.8e-12 47.1 0.0 2.8e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Rubisco Assembly chaperone C-terminal domain polyprenyl_synt PF00348.17 EWM28148.1 - 1.7e-68 230.4 0.0 2.1e-68 230.1 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 EWM28148.1 - 0.048 13.3 0.0 0.077 12.6 0.0 1.2 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Glu_cyclase_2 PF05096.12 EWM28149.1 - 7.6e-80 268.0 0.1 9e-80 267.7 0.1 1.0 1 0 0 1 1 1 1 Glutamine cyclotransferase PepSY PF03413.19 EWM28149.1 - 0.027 15.0 0.3 2.9 8.5 0.0 2.4 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain SGL PF08450.12 EWM28149.1 - 0.086 12.4 0.3 3.9 7.0 0.1 2.6 2 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region CSN8_PSD8_EIF3K PF10075.9 EWM28150.1 - 5e-21 75.2 0.0 8.6e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family DnaJ PF00226.31 EWM28151.1 - 9.6e-19 67.3 0.8 1.4e-18 66.7 0.8 1.3 1 0 0 1 1 1 1 DnaJ domain Tmemb_185A PF10269.9 EWM28151.1 - 2.6e-13 50.2 20.4 1.6e-12 47.7 19.7 2.7 1 1 1 2 2 2 2 Transmembrane Fragile-X-F protein BTB PF00651.31 EWM28152.1 - 1.7e-18 66.9 0.0 1.1e-08 35.3 0.0 4.5 3 1 1 4 4 4 3 BTB/POZ domain Ank_4 PF13637.6 EWM28152.1 - 1.4e-08 35.1 0.3 5.6e-08 33.2 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EWM28152.1 - 1.9e-06 28.4 0.1 5.4e-06 26.9 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EWM28152.1 - 6.5e-05 23.2 0.3 0.051 14.1 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EWM28152.1 - 9.4e-05 22.5 0.2 0.2 12.3 0.1 3.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 EWM28152.1 - 0.0015 18.8 0.0 0.0045 17.3 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) BET PF17035.5 EWM28152.1 - 0.074 13.2 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation C2-set PF05790.15 EWM28152.1 - 0.15 12.2 0.0 1.4 9.1 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin C2-set domain tRNA_synthFbeta PF17759.1 EWM28153.1 - 1e-43 149.3 0.0 1.4e-43 148.8 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 EWM28153.1 - 2.2e-31 107.9 0.0 6.9e-31 106.3 0.0 1.9 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 EWM28153.1 - 1.1e-20 74.0 0.0 1.9e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 EWM28153.1 - 5.1e-15 55.5 0.0 1.2e-12 47.9 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain tRNA-synt_2d PF01409.20 EWM28153.1 - 0.18 11.3 0.0 0.63 9.5 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) ketoacyl-synt PF00109.26 EWM28154.1 - 1.4e-56 191.9 0.0 2e-56 191.4 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EWM28154.1 - 1e-28 99.7 0.3 1.9e-28 98.9 0.3 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EWM28154.1 - 4.9e-05 22.8 0.2 8.1e-05 22.1 0.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain NTP_transf_2 PF01909.23 EWM28155.1 - 1e-08 35.3 0.0 3e-08 33.8 0.0 1.8 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 EWM28155.1 - 2.7e-07 30.7 0.1 9e-06 25.8 0.0 2.7 2 0 0 2 2 2 1 Cid1 family poly A polymerase Polbeta PF18765.1 EWM28155.1 - 0.044 13.9 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 EWM28156.1 - 1e-08 35.3 0.0 3e-08 33.8 0.0 1.8 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 EWM28156.1 - 2.7e-07 30.7 0.1 9e-06 25.8 0.0 2.7 2 0 0 2 2 2 1 Cid1 family poly A polymerase Polbeta PF18765.1 EWM28156.1 - 0.044 13.9 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Mito_carr PF00153.27 EWM28157.1 - 9.1e-56 185.8 0.5 5.5e-20 71.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Methyltransf_4 PF02390.17 EWM28158.1 - 8.2e-48 162.1 0.0 1.1e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 EWM28158.1 - 4.5e-05 24.1 0.0 8.4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EWM28158.1 - 5.2e-05 22.8 0.0 0.0002 21.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 EWM28158.1 - 0.0059 17.2 0.0 0.021 15.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EWM28158.1 - 0.0073 17.0 0.0 0.015 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EWM28158.1 - 0.035 13.8 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF2431 PF10354.9 EWM28158.1 - 0.14 12.4 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) RrnaAD PF00398.20 EWM28158.1 - 0.17 10.9 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 EWM28158.1 - 0.2 11.6 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain UCH PF00443.29 EWM28159.1 - 4.4e-11 42.7 0.0 9.3e-11 41.7 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EWM28159.1 - 4.2e-05 23.3 0.1 0.22 11.1 0.0 2.3 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF4667 PF15700.5 EWM28159.1 - 0.033 14.3 16.8 0.034 14.2 8.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) ANAPC1 PF12859.7 EWM28159.1 - 2.4 8.7 18.5 0.49 11.0 9.7 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 CoaE PF01121.20 EWM28160.1 - 4e-42 143.9 0.0 5e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase ANTAR PF03861.14 EWM28160.1 - 0.019 14.8 5.1 0.022 14.6 1.6 2.3 1 1 1 2 2 2 0 ANTAR domain UCR_UQCRX_QCR9 PF05365.12 EWM28160.1 - 0.38 10.7 1.1 0.7 9.9 1.1 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF4395 PF14340.6 EWM28161.1 - 0.0017 18.7 2.2 0.0045 17.3 2.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4395) DUF4131 PF13567.6 EWM28161.1 - 0.26 10.9 0.9 0.46 10.1 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Acyl_transf_3 PF01757.22 EWM28162.1 - 8.6e-20 71.1 30.8 8.6e-20 71.1 30.8 2.2 3 0 0 3 3 3 1 Acyltransferase family OppC_N PF12911.7 EWM28162.1 - 0.042 13.8 3.7 18 5.4 0.1 4.2 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C DUF2275 PF10039.9 EWM28162.1 - 0.27 11.3 1.5 2.7 8.0 0.0 2.7 3 0 0 3 3 3 0 Predicted integral membrane protein (DUF2275) DNA_pol_A_exo1 PF01612.20 EWM28163.1 - 2.5e-17 63.1 0.0 3.6e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease F_actin_cap_B PF01115.17 EWM28164.1 - 1.5e-68 231.0 0.0 1.8e-68 230.7 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein, beta subunit CAAX_1 PF15895.5 EWM28164.1 - 0.0077 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 CAAX box cerebral protein 1 Sulf_transp PF04143.14 EWM28165.1 - 1.2e-11 44.7 19.3 1e-09 38.4 6.8 3.4 2 2 0 3 3 3 2 Sulphur transport Pox_MCEL PF03291.16 EWM28166.1 - 1.3e-38 133.0 0.0 3.1e-32 112.0 0.0 2.6 2 1 0 2 2 2 2 mRNA capping enzyme Methyltransf_25 PF13649.6 EWM28166.1 - 1e-07 32.5 0.2 1.9e-05 25.3 0.2 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM28166.1 - 8.5e-07 29.5 0.2 4.2e-05 24.1 0.2 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM28166.1 - 7.3e-06 25.9 0.0 2.6e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EWM28166.1 - 7.7e-06 26.6 0.0 3.1e-05 24.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Mito_carr PF00153.27 EWM28167.1 - 1.5e-43 146.6 1.8 1.3e-14 53.9 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein ABC2_membrane PF01061.24 EWM28168.1 - 2.9e-36 124.9 10.1 2.9e-36 124.9 10.1 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 EWM28168.1 - 1.2e-20 74.5 0.0 1.9e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 EWM28168.1 - 0.00073 19.2 0.1 0.0019 17.9 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EWM28168.1 - 0.0038 17.2 0.1 0.0076 16.2 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EWM28168.1 - 0.0044 17.4 0.0 0.0072 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EWM28168.1 - 0.0052 16.6 0.2 0.55 10.0 0.1 2.2 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EWM28168.1 - 0.074 12.6 0.0 0.21 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EWM28168.1 - 0.22 12.0 0.0 0.4 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain LIAS_N PF16881.5 EWM28169.1 - 2.9e-11 43.7 0.3 8.1e-11 42.3 0.2 1.9 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 EWM28169.1 - 3.2e-10 40.6 0.0 5.2e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily ABC2_membrane PF01061.24 EWM28170.1 - 3.1e-32 111.7 22.9 4.5e-32 111.2 22.9 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EWM28170.1 - 1.7e-24 86.9 0.0 3.1e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EWM28170.1 - 7.5e-11 41.7 9.6 7.5e-11 41.7 9.6 1.9 1 1 0 2 2 2 1 ABC-2 family transporter protein AAA_16 PF13191.6 EWM28170.1 - 0.00078 19.9 0.1 0.0023 18.4 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EWM28170.1 - 0.0011 18.8 0.0 0.023 14.5 0.0 2.5 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 EWM28171.1 - 1.3e-37 129.2 0.0 5.7e-37 127.1 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EWM28171.1 - 4e-15 55.3 0.4 2.2e-14 53.0 0.1 2.5 2 0 0 2 2 2 1 AAA+ lid domain Vps4_C PF09336.10 EWM28171.1 - 1.2e-07 31.6 0.0 4.6e-07 29.7 0.0 2.0 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 EWM28171.1 - 8.8e-05 22.3 0.0 0.00016 21.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 EWM28171.1 - 0.00015 21.6 0.0 0.0048 16.6 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.6 EWM28171.1 - 0.00099 18.7 0.2 0.015 14.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EWM28171.1 - 0.0011 19.0 0.0 0.0098 15.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EWM28171.1 - 0.0011 19.2 0.2 0.021 15.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EWM28171.1 - 0.0019 18.6 0.4 0.013 15.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 EWM28171.1 - 0.0031 16.8 0.0 0.0056 15.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 EWM28171.1 - 0.0034 16.8 0.0 0.0068 15.8 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 EWM28171.1 - 0.005 17.1 0.9 0.015 15.6 0.1 2.2 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 EWM28171.1 - 0.0053 16.9 0.0 0.02 15.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 EWM28171.1 - 0.0059 16.6 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EWM28171.1 - 0.013 16.1 1.5 0.037 14.6 0.3 2.6 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EWM28171.1 - 0.035 14.3 0.5 0.16 12.2 0.5 2.2 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EWM28171.1 - 0.043 13.3 0.0 0.084 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EWM28171.1 - 0.045 14.2 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 EWM28171.1 - 0.051 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EWM28171.1 - 0.055 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.16 EWM28171.1 - 0.08 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein TsaE PF02367.17 EWM28171.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 EWM28171.1 - 0.17 11.0 0.2 0.38 9.8 0.0 1.6 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 NMT PF01233.19 EWM28172.1 - 3.4e-73 244.8 0.0 5.4e-73 244.1 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 EWM28172.1 - 4.4e-67 225.7 0.0 6.8e-67 225.0 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_1 PF00583.25 EWM28172.1 - 0.017 15.4 0.0 0.04 14.1 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 EWM28172.1 - 0.037 14.1 0.0 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Arf PF00025.21 EWM28173.1 - 5.2e-62 208.4 0.0 5.8e-62 208.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EWM28173.1 - 1.7e-09 37.3 0.2 6.7e-06 25.5 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EWM28173.1 - 3.1e-09 36.6 0.0 3.9e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EWM28173.1 - 3.9e-09 36.7 0.0 6.3e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EWM28173.1 - 2.3e-08 33.7 0.0 2.9e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EWM28173.1 - 3e-08 33.8 0.0 3.8e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EWM28173.1 - 0.00021 20.7 0.0 0.00023 20.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EWM28173.1 - 0.0016 18.0 0.0 0.09 12.3 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.19 EWM28173.1 - 0.0082 15.8 0.0 0.69 9.5 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Antibiotic_NAT PF02522.14 EWM28173.1 - 0.009 15.8 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 1 Aminoglycoside 3-N-acetyltransferase PduV-EutP PF10662.9 EWM28173.1 - 0.052 13.3 0.0 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 EWM28173.1 - 0.15 12.4 0.0 0.23 11.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EWM28173.1 - 0.15 12.6 0.0 0.23 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 EWM28173.1 - 0.15 11.6 0.1 0.51 9.8 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B Peptidase_S8 PF00082.22 EWM28174.1 - 8.6e-75 251.8 0.9 1.1e-74 251.4 0.9 1.1 1 0 0 1 1 1 1 Subtilase family 2OG-FeII_Oxy_2 PF13532.6 EWM28175.1 - 1.6e-14 54.6 0.0 2.3e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Mito_fiss_reg PF05308.11 EWM28177.1 - 0.097 12.7 0.7 0.11 12.6 0.7 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator ABC2_membrane_3 PF12698.7 EWM28178.1 - 1.1e-64 218.8 41.2 1.3e-41 142.9 13.7 3.0 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 EWM28178.1 - 1.8e-55 187.2 0.0 3.9e-30 105.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EWM28178.1 - 2.1e-18 67.2 0.4 4.1e-06 26.8 0.0 4.8 4 1 1 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EWM28178.1 - 0.00036 20.5 0.1 0.0092 15.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 EWM28178.1 - 0.0013 19.3 1.0 0.18 12.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EWM28178.1 - 0.0014 18.4 0.2 0.053 13.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EWM28178.1 - 0.0015 18.2 2.6 0.011 15.4 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EWM28178.1 - 0.014 15.2 0.1 2.1 7.9 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain SMC_N PF02463.19 EWM28178.1 - 0.015 14.7 0.0 10 5.5 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EWM28178.1 - 0.023 14.8 0.2 11 6.2 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Mg_chelatase PF01078.21 EWM28178.1 - 0.03 13.7 0.8 1.4 8.2 0.0 3.2 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI SRP54 PF00448.22 EWM28178.1 - 0.07 12.8 3.3 2.8 7.5 0.2 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 EWM28178.1 - 0.1 12.8 0.1 3.7 7.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 EWM28178.1 - 0.2 11.4 0.7 1.1 9.0 0.1 2.1 2 0 0 2 2 2 0 MukB N-terminal ABC2_membrane PF01061.24 EWM28178.1 - 1.6 8.1 49.3 0.035 13.5 17.9 4.1 4 0 0 4 4 4 0 ABC-2 type transporter ABC2_membrane_2 PF12679.7 EWM28178.1 - 3.9 6.7 37.2 6.4 6.0 8.7 3.4 3 0 0 3 3 3 0 ABC-2 family transporter protein NACHT PF05729.12 EWM28181.1 - 5.3e-10 39.5 0.0 1e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 NACHT domain SH2 PF00017.24 EWM28181.1 - 1e-09 38.3 0.1 2.2e-09 37.3 0.1 1.6 1 0 0 1 1 1 1 SH2 domain CHAT PF12770.7 EWM28181.1 - 6.9e-09 35.5 0.1 1.3e-08 34.6 0.1 1.4 1 0 0 1 1 1 1 CHAT domain AAA_16 PF13191.6 EWM28181.1 - 4.9e-07 30.3 1.8 1.5e-05 25.4 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain NB-ARC PF00931.22 EWM28181.1 - 3.5e-06 26.4 0.0 1.8e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 NB-ARC domain ATPase_2 PF01637.18 EWM28181.1 - 0.0011 18.9 0.0 0.0024 17.8 0.0 1.6 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA PF00004.29 EWM28181.1 - 0.0013 19.2 0.0 0.0036 17.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EWM28181.1 - 0.0018 18.5 0.0 0.0053 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 EWM28181.1 - 0.002 17.4 0.0 0.0034 16.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain NTPase_1 PF03266.15 EWM28181.1 - 0.0091 15.9 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 NTPase RNA_helicase PF00910.22 EWM28181.1 - 0.015 15.7 0.0 0.029 14.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Cbl_N3 PF02762.14 EWM28181.1 - 0.022 14.6 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain DUF2075 PF09848.9 EWM28181.1 - 0.094 11.9 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 EWM28181.1 - 0.1 12.9 0.0 0.22 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain DnaB_C PF03796.15 EWM28181.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 EWM28181.1 - 0.16 11.3 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2967 PF11179.8 EWM28181.1 - 4.4 5.3 4.7 6.5 4.7 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Apolipoprotein PF01442.18 EWM28182.1 - 0.00074 19.4 3.5 0.00098 19.1 3.5 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain YtxH PF12732.7 EWM28182.1 - 0.0075 16.8 3.5 0.15 12.6 1.4 2.3 1 1 1 2 2 2 2 YtxH-like protein DUF883 PF05957.13 EWM28182.1 - 0.012 16.1 6.0 3.4 8.3 6.1 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) ATP-synt_DE PF00401.20 EWM28182.1 - 3.8 7.9 8.9 2.5 8.4 0.5 2.9 2 1 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Chloroa_b-bind PF00504.21 EWM28183.1 - 1.5e-31 110.1 0.0 1.9e-31 109.8 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DSPc PF00782.20 EWM28184.1 - 6.6e-26 90.7 0.0 1.1e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EWM28184.1 - 0.0018 18.4 0.2 0.005 17.0 0.1 1.7 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 EWM28184.1 - 0.0061 16.2 0.0 0.0086 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Glutaredoxin2_C PF04399.13 EWM28187.1 - 2.4e-27 95.3 0.0 3.2e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain GST_N_3 PF13417.6 EWM28187.1 - 4.5e-09 36.6 0.0 9.9e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EWM28187.1 - 4.6e-07 30.0 0.0 8.5e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 EWM28187.1 - 0.015 15.5 0.0 0.043 14.0 0.0 1.8 1 0 0 1 1 1 0 Glutaredoxin SOUL PF04832.12 EWM28188.1 - 5.9e-43 146.9 0.2 1.3e-42 145.9 0.0 1.6 2 0 0 2 2 2 1 SOUL heme-binding protein SOUL PF04832.12 EWM28189.1 - 5.9e-43 146.9 0.2 1.3e-42 145.9 0.0 1.6 2 0 0 2 2 2 1 SOUL heme-binding protein DEAD PF00270.29 EWM28190.1 - 1.7e-18 67.0 0.0 3.2e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EWM28190.1 - 5.7e-16 58.8 0.0 3.7e-14 53.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EWM28190.1 - 1.6e-13 51.2 3.1 3.4e-13 50.1 1.7 2.2 2 0 0 2 2 2 1 RecQ zinc-binding ResIII PF04851.15 EWM28190.1 - 0.0071 16.4 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit GTP_cyclohydroI PF01227.22 EWM28191.1 - 1.1e-76 256.3 0.5 1.5e-76 255.8 0.5 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 EWM28191.1 - 0.0026 17.9 0.0 0.0045 17.1 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein Ku PF02735.16 EWM28192.1 - 8.6e-28 97.4 0.0 1.3e-27 96.9 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 EWM28192.1 - 1.8e-21 76.9 0.0 3.3e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain SAP PF02037.27 EWM28192.1 - 1.3e-09 37.6 2.6 3.1e-09 36.4 2.6 1.7 1 0 0 1 1 1 1 SAP domain Ku_C PF03730.14 EWM28192.1 - 1.9e-06 28.5 0.0 6e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm 6PF2K PF01591.18 EWM28193.1 - 1.5e-53 181.4 0.0 2.2e-53 180.9 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EWM28193.1 - 1.7e-34 119.2 0.0 3.5e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EWM28193.1 - 2.6e-06 27.7 0.0 4.6e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EWM28193.1 - 0.034 13.6 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DER1 PF04511.15 EWM28194.1 - 3e-55 187.1 10.5 3.6e-55 186.9 10.5 1.1 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.22 EWM28194.1 - 0.013 15.5 6.6 0.013 15.5 6.6 1.5 2 0 0 2 2 2 0 Rhomboid family Fer2 PF00111.27 EWM28195.1 - 3.5e-08 33.3 1.7 6.2e-08 32.5 1.7 1.5 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Cupredoxin_1 PF13473.6 EWM28195.1 - 0.025 14.7 0.0 0.045 13.9 0.0 1.5 1 0 0 1 1 1 0 Cupredoxin-like domain GMC_oxred_N PF00732.19 EWM28196.1 - 7.5e-70 235.6 0.0 8.9e-38 130.3 0.0 2.2 1 1 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 EWM28196.1 - 9.1e-36 123.5 0.0 1.4e-35 122.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EWM28196.1 - 0.0001 21.5 0.0 0.00014 21.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EWM28196.1 - 0.00013 21.2 0.1 0.043 12.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EWM28196.1 - 0.0011 19.2 0.1 0.0045 17.2 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EWM28196.1 - 0.0013 18.4 0.2 0.0067 16.1 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EWM28196.1 - 0.0029 16.9 0.0 0.0047 16.2 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EWM28196.1 - 0.0029 16.9 0.0 0.0085 15.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EWM28196.1 - 0.12 11.1 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein TPR_14 PF13428.6 EWM28197.1 - 4.4e-31 104.9 39.8 0.00038 21.0 0.1 14.7 5 4 11 16 16 16 12 Tetratricopeptide repeat PRP1_N PF06424.12 EWM28197.1 - 3e-27 95.8 3.6 3.1e-27 95.8 2.3 1.7 2 0 0 2 2 1 1 PRP1 splicing factor, N-terminal TPR_19 PF14559.6 EWM28197.1 - 1.5e-22 79.8 12.0 1.3e-06 28.9 0.1 10.5 8 3 2 11 11 11 5 Tetratricopeptide repeat TPR_16 PF13432.6 EWM28197.1 - 1.2e-14 54.7 19.6 0.0095 16.6 1.3 8.2 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 EWM28197.1 - 4.4e-12 45.5 4.2 20 5.9 0.0 10.4 9 2 1 10 10 10 0 Tetratricopeptide repeat TPR_2 PF07719.17 EWM28197.1 - 1.4e-10 40.4 14.4 0.005 16.9 0.0 9.7 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_8 PF13181.6 EWM28197.1 - 4.2e-10 39.0 1.5 0.26 11.6 0.0 7.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 EWM28197.1 - 2e-05 24.2 1.8 0.29 11.0 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat NRDE-2 PF08424.10 EWM28197.1 - 0.00042 19.5 16.1 0.14 11.2 0.2 5.7 3 2 2 5 5 5 2 NRDE-2, necessary for RNA interference TPR_9 PF13371.6 EWM28197.1 - 0.0005 20.2 13.6 1.8 8.8 0.0 6.2 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 EWM28197.1 - 0.0011 19.3 4.5 5.1 7.5 0.0 5.9 6 1 1 7 7 7 2 Tetratricopeptide repeat SCAN PF02023.17 EWM28197.1 - 0.045 13.6 2.7 1.9 8.4 0.2 3.8 2 1 2 4 4 4 0 SCAN domain DUF3417 PF11897.8 EWM28197.1 - 0.14 12.7 0.8 1.8 9.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3417) TPR_11 PF13414.6 EWM28197.1 - 0.42 10.3 6.5 11 5.8 0.0 5.9 7 0 0 7 7 7 0 TPR repeat TPR_6 PF13174.6 EWM28197.1 - 2.1 9.1 19.1 12 6.7 0.0 9.1 12 0 0 12 12 9 0 Tetratricopeptide repeat PseudoU_synth_2 PF00849.22 EWM28198.1 - 2.1e-24 86.4 0.0 3.7e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 EWM28198.1 - 3e-05 23.7 0.0 6.1e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 S4 domain PA-IL PF07828.12 EWM28198.1 - 0.016 15.2 0.1 0.03 14.3 0.1 1.5 1 0 0 1 1 1 0 PA-IL-like protein DUF2149 PF09919.9 EWM28198.1 - 0.31 11.3 1.1 1.5 9.1 0.3 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) TFIIA PF03153.13 EWM28199.1 - 0.018 15.1 6.6 0.019 15.0 6.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RRM_1 PF00076.22 EWM28200.1 - 1e-22 79.7 0.0 5.7e-12 45.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_4 PF15227.6 EWM28200.1 - 2.5e-08 34.0 6.7 4.6e-08 33.1 6.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 EWM28200.1 - 1.3e-07 31.3 5.5 2.3e-07 30.6 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EWM28200.1 - 1.6e-07 31.2 4.2 3.2e-07 30.3 4.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EWM28200.1 - 2.4e-06 27.3 4.5 4.2e-06 26.5 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EWM28200.1 - 2.9e-05 23.9 4.4 5.4e-05 23.1 4.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EWM28200.1 - 9.6e-05 22.1 6.8 0.00019 21.2 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EWM28200.1 - 0.00013 22.3 7.2 0.00022 21.5 7.2 1.4 1 0 0 1 1 1 1 Ring finger domain RNA_bind PF08675.11 EWM28200.1 - 0.00014 21.8 0.0 0.0054 16.7 0.0 2.3 2 0 0 2 2 2 1 RNA binding domain RRM_7 PF16367.5 EWM28200.1 - 0.001 19.1 0.0 0.089 12.9 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif zinc_ribbon_9 PF14369.6 EWM28200.1 - 0.095 13.0 3.5 1.7 9.0 0.7 2.7 2 0 0 2 2 2 0 zinc-ribbon Prok-RING_4 PF14447.6 EWM28200.1 - 0.16 11.8 6.9 0.66 9.9 7.2 1.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EWM28200.1 - 0.35 10.7 2.1 0.31 10.9 0.4 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Methyltransf_11 PF08241.12 EWM28201.1 - 5.3e-21 75.1 0.0 9.6e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM28201.1 - 3.4e-19 69.3 0.0 7e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EWM28201.1 - 1.8e-11 43.9 0.0 2.5e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EWM28201.1 - 3.6e-11 43.7 0.0 6.1e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM28201.1 - 3.9e-09 36.5 0.0 7.5e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EWM28201.1 - 4.9e-08 33.0 0.0 7.2e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EWM28201.1 - 1.2e-05 24.9 0.0 9.2e-05 22.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 EWM28201.1 - 0.00017 20.9 0.0 0.00027 20.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Rsm22 PF09243.10 EWM28201.1 - 0.00018 20.9 0.0 0.00026 20.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_24 PF13578.6 EWM28201.1 - 0.0027 18.7 0.0 0.0046 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EWM28201.1 - 0.014 15.6 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_8 PF05148.15 EWM28201.1 - 0.019 14.8 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase PCMT PF01135.19 EWM28201.1 - 0.049 13.4 0.0 0.085 12.6 0.0 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 EWM28201.1 - 0.072 12.6 0.0 0.39 10.2 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase ABC1 PF03109.16 EWM28203.1 - 2.9e-31 108.1 0.0 5.6e-31 107.2 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 EWM28203.1 - 8.8e-05 22.0 0.0 0.028 13.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 EWM28203.1 - 0.001 19.1 0.9 0.001 19.1 0.9 2.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family C2 PF00168.30 EWM28204.1 - 3.6e-09 36.8 0.0 5.1e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 C2 domain CTP_transf_like PF01467.26 EWM28205.1 - 1.6e-31 109.4 0.0 2.9e-18 66.4 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 EWM28205.1 - 0.0043 16.9 0.1 4.4 7.2 0.0 3.2 3 0 0 3 3 3 2 FAD synthetase LapA_dom PF06305.11 EWM28205.1 - 2 8.3 5.3 0.36 10.7 1.3 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Met_gamma_lyase PF06838.11 EWM28206.1 - 6.9e-154 512.2 0.0 1.1e-153 511.5 0.0 1.3 1 1 0 1 1 1 1 Methionine gamma-lyase Aminotran_1_2 PF00155.21 EWM28206.1 - 0.00015 21.1 0.0 0.048 12.8 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EWM28206.1 - 0.001 17.7 0.0 0.48 8.9 0.0 2.1 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme DAGAT PF03982.13 EWM28207.1 - 9.3e-34 116.7 0.0 1.3e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.21 EWM28207.1 - 0.0024 17.5 0.0 0.0053 16.4 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase Tom7 PF08038.12 EWM28207.1 - 0.03 14.0 0.0 0.082 12.6 0.0 1.7 1 0 0 1 1 1 0 TOM7 family PH PF00169.29 EWM28208.1 - 1.6e-06 28.6 0.0 3.5e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 EWM28208.1 - 0.0025 18.2 0.0 0.0055 17.1 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 EWM28208.1 - 0.17 12.2 0.0 0.44 10.8 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain PPR_2 PF13041.6 EWM28211.1 - 7.9e-53 176.5 0.0 3.2e-05 24.0 0.0 15.3 10 4 6 16 16 16 13 PPR repeat family PPR PF01535.20 EWM28211.1 - 1.2e-48 160.0 16.5 0.0035 17.5 0.0 19.2 19 1 0 19 19 19 11 PPR repeat PPR_3 PF13812.6 EWM28211.1 - 5.1e-38 129.0 0.0 2.1e-06 27.7 0.0 11.5 10 2 3 13 13 13 7 Pentatricopeptide repeat domain PPR_long PF17177.4 EWM28211.1 - 3e-23 82.3 1.2 1.4e-05 24.5 0.0 6.1 2 2 3 6 6 6 5 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EWM28211.1 - 9.5e-16 57.2 4.7 0.22 11.2 0.0 9.9 10 0 0 10 10 10 4 PPR repeat TPR_12 PF13424.6 EWM28211.1 - 2.6e-06 27.6 7.4 0.0042 17.3 0.3 5.9 5 1 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EWM28211.1 - 0.0029 17.8 0.5 16 5.8 0.0 5.0 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EWM28211.1 - 0.016 15.2 9.1 25 5.2 0.0 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 EWM28211.1 - 0.028 14.5 10.9 74 3.8 0.2 6.7 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 EWM28211.1 - 0.092 13.6 43.9 6 8.0 1.6 13.0 12 2 2 15 15 15 0 Tetratricopeptide repeat TPR_6 PF13174.6 EWM28211.1 - 0.88 10.3 8.9 71 4.4 0.0 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 EWM28211.1 - 1.2 9.7 29.0 16 6.1 0.4 9.5 7 3 2 10 10 10 0 Tetratricopeptide repeat TPR_10 PF13374.6 EWM28211.1 - 3.3 7.7 12.7 8.1 6.5 0.0 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF4506 PF14958.6 EWM28212.1 - 8.1e-05 22.2 0.0 0.00016 21.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4506) WD40 PF00400.32 EWM28213.1 - 1.5e-38 130.1 11.4 3.1e-08 34.2 0.0 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM28213.1 - 1.7e-12 47.5 0.9 0.066 13.5 0.1 5.5 2 2 5 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EWM28213.1 - 5.4e-11 41.8 3.5 0.011 14.5 0.0 4.9 2 1 3 5 5 5 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EWM28213.1 - 7.7e-08 31.7 0.0 0.24 10.3 0.0 4.6 3 1 1 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EWM28213.1 - 0.00025 19.9 0.9 0.15 10.8 0.0 3.5 1 1 3 4 4 4 2 Nup133 N terminal like Cytochrom_D1 PF02239.16 EWM28213.1 - 0.021 13.4 0.0 3.5 6.1 0.0 2.4 2 1 0 2 2 2 0 Cytochrome D1 heme domain Hira PF07569.11 EWM28213.1 - 0.1 12.3 0.9 21 4.7 0.1 3.2 2 1 1 3 3 3 0 TUP1-like enhancer of split WD40 PF00400.32 EWM28214.1 - 3e-24 84.8 23.4 1.9e-05 25.3 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.8 EWM28214.1 - 0.11 11.1 0.7 0.2 10.3 0.3 1.6 2 0 0 2 2 2 0 Nucleoporin Nup120/160 rhaM PF05336.13 EWM28215.1 - 0.078 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 L-rhamnose mutarotase Amidohydro_3 PF07969.11 EWM28216.1 - 3.5e-81 274.1 0.0 4e-81 273.9 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 EWM28216.1 - 6.6e-16 58.5 0.0 1.1e-11 44.7 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 EWM28217.1 - 3.1e-81 274.2 0.0 3.6e-81 274.0 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 EWM28217.1 - 6.4e-16 58.6 0.0 1.1e-11 44.7 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family Golgin_A5 PF09787.9 EWM28218.1 - 0.00016 21.3 5.6 0.00016 21.3 5.6 1.6 2 0 0 2 2 2 1 Golgin subfamily A member 5 Baculo_PEP_C PF04513.12 EWM28218.1 - 0.65 10.0 3.8 1.7 8.7 1.2 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fez1 PF06818.15 EWM28218.1 - 8.2 6.8 13.6 0.67 10.4 8.3 1.9 2 0 0 2 2 2 0 Fez1 TFIIA PF03153.13 EWM28218.1 - 9.7 6.1 17.2 0.96 9.4 5.9 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit IU_nuc_hydro PF01156.19 EWM28219.1 - 4.7e-81 272.7 0.0 5.8e-81 272.4 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase PPR_3 PF13812.6 EWM28220.1 - 5.3e-111 362.7 0.0 3.1e-13 49.6 0.0 13.6 8 5 4 13 13 13 12 Pentatricopeptide repeat domain PPR_2 PF13041.6 EWM28220.1 - 1.7e-107 351.5 8.6 1.4e-12 47.6 0.0 15.8 8 3 10 18 18 18 17 PPR repeat family PPR_1 PF12854.7 EWM28220.1 - 6.1e-103 336.2 3.8 1.1e-08 34.7 0.0 19.5 20 0 0 20 20 20 16 PPR repeat PPR PF01535.20 EWM28220.1 - 2.6e-96 309.4 23.0 4.3e-06 26.6 0.1 21.2 21 1 0 21 21 21 17 PPR repeat PPR_long PF17177.4 EWM28220.1 - 4.9e-54 182.9 8.1 2.8e-13 49.7 0.0 7.7 2 2 5 7 7 7 6 Pentacotripeptide-repeat region of PRORP Aa_trans PF01490.18 EWM28220.1 - 1.7e-31 109.3 18.4 2.9e-31 108.6 18.4 1.4 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TPR_14 PF13428.6 EWM28220.1 - 1.4e-19 69.1 43.0 2 9.5 0.1 18.0 8 4 9 18 18 18 4 Tetratricopeptide repeat TPR_19 PF14559.6 EWM28220.1 - 1.8e-12 47.6 14.4 0.36 11.4 0.1 9.9 8 2 1 10 10 10 3 Tetratricopeptide repeat Wzy_C_2 PF11846.8 EWM28220.1 - 3.2e-07 30.5 14.4 10 6.0 0.0 10.5 6 2 5 12 12 12 1 Virulence factor membrane-bound polymerase, C-terminal TPR_4 PF07721.14 EWM28220.1 - 6.1e-06 26.4 20.8 0.19 12.4 0.1 10.8 11 0 0 11 11 9 1 Tetratricopeptide repeat TPR_7 PF13176.6 EWM28220.1 - 6.4e-06 25.8 0.2 9.4 6.5 0.0 7.6 8 0 0 8 8 8 1 Tetratricopeptide repeat MRP-S27 PF10037.9 EWM28220.1 - 0.00021 20.3 0.0 0.23 10.3 0.0 3.2 2 1 1 4 4 4 2 Mitochondrial 28S ribosomal protein S27 MFS_Mycoplasma PF07672.13 EWM28220.1 - 0.14 11.4 1.2 0.28 10.4 1.2 1.4 1 0 0 1 1 1 0 Mycoplasma MFS transporter Ferritin PF00210.24 EWM28220.1 - 0.23 11.4 0.1 10 6.1 0.0 2.9 3 0 0 3 3 3 0 Ferritin-like domain B12-binding_2 PF02607.17 EWM28220.1 - 3.2 8.3 8.4 1.5e+02 2.9 0.1 6.4 4 2 1 5 5 5 0 B12 binding domain Tim44 PF04280.15 EWM28221.1 - 0.04 14.0 0.1 0.088 12.9 0.1 1.6 1 0 0 1 1 1 0 Tim44-like domain BID PF06393.11 EWM28221.1 - 0.17 11.4 0.1 0.32 10.5 0.1 1.4 1 0 0 1 1 1 0 BH3 interacting domain (BID) Alg6_Alg8 PF03155.15 EWM28221.1 - 0.2 10.6 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 ALG6, ALG8 glycosyltransferase family DUF2431 PF10354.9 EWM28222.1 - 1.4e-26 93.8 0.0 2.3e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) zf-C2H2 PF00096.26 EWM28222.1 - 9e-09 35.3 12.8 0.0033 17.8 1.1 5.1 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EWM28222.1 - 1.1e-08 35.2 12.3 0.07 14.0 0.0 4.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.7 EWM28222.1 - 2.3e-06 27.8 4.8 0.73 10.3 0.0 4.7 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EWM28222.1 - 3.3e-05 24.1 11.9 0.19 12.0 0.0 4.7 5 0 0 5 5 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 EWM28222.1 - 0.018 15.7 0.7 0.083 13.6 0.1 2.4 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 EWM28222.1 - 0.019 15.3 8.4 3.1 8.2 0.4 3.8 2 2 1 3 3 3 0 C2H2 type zinc-finger (2 copies) C1_1 PF00130.22 EWM28222.1 - 0.055 13.4 1.2 7.5 6.5 0.7 2.8 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_6 PF13912.6 EWM28222.1 - 0.055 13.5 15.2 1.7 8.7 0.5 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EWM28222.1 - 0.11 13.0 15.9 1.3 9.6 0.0 5.3 6 0 0 6 6 5 0 Zinc-finger double domain zinc_ribbon_15 PF17032.5 EWM28222.1 - 0.12 13.1 2.3 14 6.5 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon family zf-Di19 PF05605.12 EWM28222.1 - 0.28 11.5 4.1 8 6.8 0.0 3.5 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-SNAP50_C PF12251.8 EWM28222.1 - 0.28 10.8 4.7 0.098 12.3 0.7 1.9 2 0 0 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal zf-C2H2_11 PF16622.5 EWM28222.1 - 0.51 10.2 4.7 3.3 7.6 0.1 3.7 4 0 0 4 4 4 0 zinc-finger C2H2-type SF3b10 PF07189.11 EWM28223.1 - 1.2e-37 127.8 0.1 1.4e-37 127.6 0.1 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) RRM_3 PF08777.11 EWM28223.1 - 0.028 14.4 0.0 0.039 14.0 0.0 1.2 1 0 0 1 1 1 0 RNA binding motif Longin PF13774.6 EWM28223.1 - 0.12 12.5 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Regulated-SNARE-like domain DSPc PF00782.20 EWM28224.1 - 2.7e-05 24.0 0.0 6.4e-05 22.8 0.0 1.5 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EWM28224.1 - 0.00038 20.1 0.0 0.00055 19.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EWM28224.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Tyrosine phosphatase family Adaptin_binding PF10199.9 EWM28225.1 - 8.8e-06 26.3 0.2 1.7e-05 25.4 0.2 1.5 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 adh_short PF00106.25 EWM28226.1 - 2.6e-43 147.7 0.0 3.6e-43 147.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EWM28226.1 - 1.7e-21 76.9 0.0 3.3e-21 75.9 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM28226.1 - 1.2e-09 38.3 0.0 4.1e-09 36.6 0.0 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EWM28226.1 - 0.0015 18.1 0.0 0.046 13.2 0.0 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EWM28226.1 - 0.025 14.4 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding PhoR PF11808.8 EWM28226.1 - 0.11 13.0 0.5 0.28 11.6 0.5 1.7 1 0 0 1 1 1 0 Phosphate regulon sensor protein PhoR Peptidase_S9 PF00326.21 EWM28227.1 - 5.7e-33 114.2 0.0 1.6e-31 109.5 0.0 2.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 EWM28227.1 - 1.9e-26 92.8 0.0 2.5e-22 79.3 0.0 2.7 2 1 0 2 2 2 2 Prolyl oligopeptidase, N-terminal beta-propeller domain Hydrolase_4 PF12146.8 EWM28227.1 - 0.0025 17.1 0.0 0.005 16.1 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Solute_trans_a PF03619.16 EWM28229.1 - 5.8e-80 268.6 13.3 7.6e-80 268.2 13.3 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF373 PF04123.13 EWM28229.1 - 0.34 10.3 4.2 0.64 9.4 4.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF373) RWD PF05773.22 EWM28230.1 - 9.4e-15 54.9 0.5 1.7e-14 54.1 0.0 1.7 2 0 0 2 2 2 1 RWD domain DFRP_C PF16543.5 EWM28230.1 - 0.0058 17.1 7.1 0.0058 17.1 7.1 3.3 1 1 2 3 3 3 1 DRG Family Regulatory Proteins, Tma46 YL1 PF05764.13 EWM28230.1 - 0.42 10.7 27.1 0.033 14.3 21.0 2.0 2 0 0 2 2 2 0 YL1 nuclear protein DUF2457 PF10446.9 EWM28230.1 - 0.5 9.5 20.8 0.98 8.5 20.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Fer2 PF00111.27 EWM28231.1 - 2.1e-14 53.2 1.4 2.9e-14 52.8 1.4 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain SP2 PF03014.14 EWM28231.1 - 0.052 12.0 0.0 0.062 11.7 0.0 1.1 1 0 0 1 1 1 0 Structural protein 2 Spore_YhaL PF14147.6 EWM28232.1 - 0.12 12.1 0.3 0.48 10.1 0.3 2.1 1 0 0 1 1 1 0 Sporulation protein YhaL APS_kinase PF01583.20 EWM28233.1 - 5.7e-64 214.8 0.0 1.1e-63 213.9 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.17 EWM28233.1 - 2.7e-54 183.9 0.0 5.1e-54 183.0 0.0 1.4 1 0 0 1 1 1 1 ATP-sulfurylase Pyrophosphatase PF00719.19 EWM28233.1 - 4.4e-38 130.6 0.0 6.5e-38 130.1 0.0 1.3 1 0 0 1 1 1 1 Inorganic pyrophosphatase PUA_2 PF14306.6 EWM28233.1 - 1.1e-34 119.4 0.0 9.1e-34 116.4 0.0 2.6 3 0 0 3 3 3 1 PUA-like domain AAA_33 PF13671.6 EWM28233.1 - 6.1e-05 23.2 0.0 0.00014 22.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EWM28233.1 - 0.00067 19.0 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 EWM28233.1 - 0.0017 18.9 0.0 0.0043 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EWM28233.1 - 0.011 16.3 0.0 0.022 15.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 EWM28233.1 - 0.013 15.2 0.1 0.041 13.6 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain KTI12 PF08433.10 EWM28233.1 - 0.083 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_17 PF13207.6 EWM28233.1 - 0.16 12.4 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EWM28233.1 - 0.18 11.5 0.0 0.42 10.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EWM28233.1 - 0.19 12.1 0.0 0.44 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase HMG_box PF00505.19 EWM28234.1 - 3.1e-18 65.9 2.7 3.1e-18 65.9 2.7 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EWM28234.1 - 2.6e-13 50.3 1.3 2.6e-13 50.3 1.3 2.3 2 0 0 2 2 2 1 HMG-box domain CDC45 PF02724.14 EWM28234.1 - 0.85 7.8 10.3 0.88 7.8 10.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2201_N PF13203.6 EWM28234.1 - 4.3 6.9 11.5 7.9 6.0 11.5 1.6 1 1 0 1 1 1 0 Putative metallopeptidase domain YABBY PF04690.13 EWM28234.1 - 5.9 7.4 8.0 1.4 9.4 0.1 2.1 1 1 1 2 2 2 0 YABBY protein Cyclin_N PF00134.23 EWM28235.1 - 7e-19 67.8 0.0 1.2e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EWM28235.1 - 6.9e-06 26.1 0.1 1.7e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain RRM_1 PF00076.22 EWM28236.1 - 2e-15 56.3 0.0 6.4e-07 29.1 0.0 4.9 5 0 0 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S5 PF00333.20 EWM28236.1 - 3.8e-15 55.6 0.1 3.8e-15 55.6 0.1 2.4 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EWM28236.1 - 5.8e-07 28.9 0.0 1.2e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain RRM_7 PF16367.5 EWM28236.1 - 1.4e-05 25.2 0.0 0.92 9.7 0.0 3.8 4 0 0 4 4 4 2 RNA recognition motif SET PF00856.28 EWM28237.1 - 1.3e-07 32.2 0.0 0.00013 22.4 0.0 2.2 1 1 0 1 1 1 1 SET domain HydF_tetramer PF18133.1 EWM28238.1 - 0.0046 16.7 0.3 1.2 8.9 0.0 3.3 3 0 0 3 3 3 1 Hydrogen maturase F tetramerization domain tRNA_bind PF01588.20 EWM28239.1 - 5.6e-29 100.1 0.0 1.1e-28 99.2 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain fn3 PF00041.21 EWM28239.1 - 1.3e-07 31.9 0.0 2.7e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 EWM28239.1 - 0.11 13.1 0.2 0.46 11.1 0.2 2.0 1 1 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain ZnuA PF01297.17 EWM28240.1 - 0.017 14.6 0.1 0.078 12.4 0.0 1.8 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic WXG100 PF06013.12 EWM28240.1 - 4.4 7.6 8.2 9.4 6.5 0.1 3.2 3 0 0 3 3 3 0 Proteins of 100 residues with WXG ZnuA PF01297.17 EWM28241.1 - 0.02 14.3 0.1 0.04 13.3 0.0 1.4 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic HAD_2 PF13419.6 EWM28241.1 - 0.16 12.1 0.0 0.3 11.1 0.0 1.6 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase WXG100 PF06013.12 EWM28241.1 - 0.89 9.8 7.9 5.4 7.3 0.1 3.1 3 0 0 3 3 3 0 Proteins of 100 residues with WXG IFT57 PF10498.9 EWM28242.1 - 1.6e-14 53.7 6.9 6e-14 51.8 0.9 2.6 1 1 1 2 2 2 1 Intra-flagellar transport protein 57 Fib_alpha PF08702.10 EWM28242.1 - 0.0069 16.6 10.3 0.015 15.5 10.3 1.5 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Neur_chan_memb PF02932.16 EWM28242.1 - 2.5 8.1 5.7 3.9 7.4 5.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Rieske PF00355.26 EWM28243.1 - 1.7e-13 50.3 0.3 4e-13 49.1 0.1 1.7 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain CytB6-F_Fe-S PF08802.10 EWM28243.1 - 4.7e-12 45.7 0.9 4.7e-12 45.7 0.9 1.8 2 0 0 2 2 2 1 Cytochrome B6-F complex Fe-S subunit WHAMM-JMY_N PF15920.5 EWM28243.1 - 0.011 15.5 0.2 0.03 14.2 0.2 1.7 1 0 0 1 1 1 0 N-terminal of Junction-mediating and WASP homolog-associated Cyt-b5 PF00173.28 EWM28245.1 - 3.4e-17 62.3 0.1 7e-17 61.3 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PWWP PF00855.17 EWM28247.1 - 4.5e-12 46.2 0.3 1.6e-11 44.4 0.3 2.0 1 0 0 1 1 1 1 PWWP domain Med26 PF08711.11 EWM28247.1 - 4.8e-09 36.1 0.4 3.5e-08 33.3 0.0 2.3 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Sec7 PF01369.20 EWM28249.1 - 4e-47 160.2 0.0 6.5e-47 159.6 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EWM28249.1 - 2.9e-15 56.5 1.0 5.5e-15 55.6 0.3 1.8 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal PH PF00169.29 EWM28249.1 - 1.4e-06 28.8 0.1 2.8e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 EWM28249.1 - 0.00013 21.8 2.5 0.013 15.3 2.5 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain ACBP PF00887.19 EWM28249.1 - 0.00082 19.5 0.0 0.0022 18.2 0.0 1.7 1 0 0 1 1 1 1 Acyl CoA binding protein DUF2464 PF10240.9 EWM28249.1 - 0.0028 17.3 0.0 0.46 10.0 0.0 2.5 1 1 2 3 3 3 3 Multivesicular body subunit 12 COPIIcoated_ERV PF07970.12 EWM28250.1 - 1.4e-69 234.4 0.0 1.8e-69 233.9 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EWM28250.1 - 4.5e-23 81.4 0.0 8.8e-23 80.5 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF1980 PF09323.10 EWM28250.1 - 0.17 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) G0-G1_switch_2 PF15103.6 EWM28250.1 - 4.3 7.8 5.0 7.8 7.0 0.7 2.3 2 0 0 2 2 2 0 G0/G1 switch protein 2 Methyltransf_32 PF13679.6 EWM28251.1 - 5.1e-33 114.3 0.3 2.7e-31 108.7 0.1 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM28251.1 - 4.1e-15 55.9 0.0 7.8e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM28251.1 - 2.4e-08 34.6 0.1 5.7e-08 33.4 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM28251.1 - 0.00045 20.8 0.0 0.001 19.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EWM28251.1 - 0.0022 17.8 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 EWM28251.1 - 0.0024 17.7 0.0 0.0045 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TRM13 PF05206.14 EWM28251.1 - 0.0029 17.2 0.0 1.6 8.2 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase TRM13 Methyltransf_12 PF08242.12 EWM28251.1 - 0.062 14.0 0.0 0.22 12.3 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain CAP160 PF07918.11 EWM28251.1 - 0.17 11.7 0.0 0.4 10.4 0.0 1.6 1 0 0 1 1 1 0 CAP160 repeat LNS2 PF08235.13 EWM28252.1 - 7.1e-51 172.8 0.0 1.1e-50 172.3 0.0 1.1 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Peptidase_C53 PF05550.11 EWM28252.1 - 0.052 13.2 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Pestivirus Npro endopeptidase C53 Lipin_N PF04571.14 EWM28252.1 - 0.075 13.0 0.0 20 5.2 0.0 2.9 3 0 0 3 3 3 0 lipin, N-terminal conserved region DMRL_synthase PF00885.19 EWM28253.1 - 4.8e-54 182.0 0.1 6.5e-54 181.6 0.1 1.2 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase DUF1719 PF08224.11 EWM28253.1 - 0.12 11.4 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1719) TMEM164 PF14808.6 EWM28255.1 - 2.4e-19 69.7 7.4 3e-19 69.4 7.4 1.0 1 0 0 1 1 1 1 TMEM164 family SBF PF01758.16 EWM28256.1 - 1.3e-33 116.3 14.3 1.3e-33 116.3 14.3 1.9 2 1 1 3 3 3 1 Sodium Bile acid symporter family Adap_comp_sub PF00928.21 EWM28257.1 - 1.8e-67 227.5 0.0 2.5e-67 227.0 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EWM28257.1 - 0.0024 17.8 0.0 0.0038 17.2 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain WD40 PF00400.32 EWM28258.1 - 2.9e-13 50.0 2.6 0.0022 18.8 0.3 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM28258.1 - 0.00012 22.3 0.1 0.22 11.8 0.0 3.9 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain AA_kinase PF00696.28 EWM28259.1 - 4.9e-46 157.3 0.0 8.4e-46 156.5 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 EWM28259.1 - 1.4e-06 28.0 2.7 0.018 14.8 0.0 3.1 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.6 EWM28259.1 - 2e-06 27.5 2.2 9.4e-05 22.1 0.5 2.6 2 0 0 2 2 2 1 ACT domain SecD-TM1 PF13721.6 EWM28259.1 - 0.0055 17.1 0.1 2.4 8.7 0.0 2.8 2 0 0 2 2 2 2 SecD export protein N-terminal TM region DUF2007 PF09413.10 EWM28259.1 - 0.015 15.4 0.4 0.15 12.2 0.1 2.7 3 0 0 3 3 3 0 Putative prokaryotic signal transducing protein DUF4611 PF15387.6 EWM28259.1 - 0.17 12.1 0.2 0.8 10.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) PknG_TPR PF16918.5 EWM28259.1 - 0.17 10.5 2.1 2.6 6.7 0.9 2.2 2 0 0 2 2 2 0 Protein kinase G tetratricopeptide repeat ECH_2 PF16113.5 EWM28260.1 - 1.5e-48 166.0 0.0 1.2e-29 103.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EWM28260.1 - 2e-10 40.4 0.0 3.8e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase HSCB_C PF07743.13 EWM28261.1 - 0.094 13.2 0.2 0.094 13.2 0.2 2.2 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain Brix PF04427.18 EWM28262.1 - 7.8e-30 104.4 0.0 1.2e-29 103.8 0.0 1.3 1 0 0 1 1 1 1 Brix domain Bromodomain PF00439.25 EWM28262.1 - 0.073 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Bromodomain Orn_Arg_deC_N PF02784.16 EWM28263.1 - 9.7e-79 264.2 0.0 1.3e-78 263.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EWM28263.1 - 1.3e-16 60.6 0.0 9.1e-16 57.9 0.0 2.1 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Peptidase_M24 PF00557.24 EWM28264.1 - 6.1e-43 147.0 0.0 1.1e-42 146.1 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 SRP72 PF08492.12 EWM28264.1 - 0.73 10.3 8.0 3.6 8.1 1.5 2.5 2 0 0 2 2 2 0 SRP72 RNA-binding domain DUF4604 PF15377.6 EWM28264.1 - 1.2 9.5 26.2 2.1 8.7 26.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) LYRIC PF15686.5 EWM28264.1 - 1.4 8.4 17.9 2.1 7.8 17.9 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family SRP-alpha_N PF04086.13 EWM28264.1 - 7.6 6.4 16.5 13 5.6 16.1 1.5 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Nitroreductase PF00881.24 EWM28266.1 - 7.9e-20 71.6 0.2 3.6e-19 69.4 0.2 1.9 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 EWM28266.1 - 0.16 11.5 0.0 0.46 10.0 0.0 1.6 2 0 0 2 2 2 0 Putative TM nitroreductase MMR_HSR1 PF01926.23 EWM28267.1 - 3.3e-53 178.6 0.4 7.1e-28 97.0 0.2 2.6 3 0 0 3 3 3 2 50S ribosome-binding GTPase KH_dom-like PF14714.6 EWM28267.1 - 4.5e-29 100.6 0.0 7.7e-29 99.8 0.0 1.4 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.18 EWM28267.1 - 3.5e-22 78.6 0.4 2.9e-13 49.6 0.1 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 EWM28267.1 - 4.8e-18 65.4 2.1 2.6e-09 36.9 0.5 5.0 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 EWM28267.1 - 3.1e-12 46.3 0.0 1.8e-05 24.2 0.0 2.8 3 0 0 3 3 3 2 AIG1 family Dynamin_N PF00350.23 EWM28267.1 - 7.2e-10 39.2 0.1 0.0085 16.2 0.0 4.7 5 0 0 5 5 5 2 Dynamin family Roc PF08477.13 EWM28267.1 - 1.5e-09 38.1 0.1 0.0037 17.5 0.0 3.4 2 2 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 EWM28267.1 - 9.3e-08 32.2 0.0 0.033 14.1 0.0 3.5 3 0 0 3 3 3 2 RsgA GTPase Ras PF00071.22 EWM28267.1 - 6.5e-07 29.1 0.3 0.00018 21.1 0.2 2.8 2 1 0 2 2 2 1 Ras family ABC_tran PF00005.27 EWM28267.1 - 1.2e-06 29.0 0.0 0.037 14.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter TniB PF05621.11 EWM28267.1 - 3.3e-06 26.6 0.0 0.056 12.8 0.0 2.9 2 1 1 3 3 3 2 Bacterial TniB protein AAA_24 PF13479.6 EWM28267.1 - 4.2e-05 23.4 0.0 0.13 12.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain cobW PF02492.19 EWM28267.1 - 0.00023 20.8 0.7 0.032 13.8 0.3 3.2 2 1 1 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 EWM28267.1 - 0.00054 20.4 0.1 0.75 10.2 0.0 3.2 2 1 0 3 3 3 1 AAA ATPase domain MeaB PF03308.16 EWM28267.1 - 0.00057 18.9 2.8 2 7.3 0.0 3.4 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 EWM28267.1 - 0.00069 20.2 0.0 2.1 8.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain Guanylate_kin PF00625.21 EWM28267.1 - 0.00077 19.2 0.0 0.043 13.5 0.0 2.4 2 0 0 2 2 2 1 Guanylate kinase RNA_helicase PF00910.22 EWM28267.1 - 0.00085 19.7 0.0 0.32 11.4 0.0 3.0 3 0 0 3 3 3 1 RNA helicase AAA_22 PF13401.6 EWM28267.1 - 0.001 19.4 0.0 2.4 8.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain NTPase_1 PF03266.15 EWM28267.1 - 0.014 15.3 0.0 1.4 8.8 0.0 2.6 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.22 EWM28267.1 - 0.043 13.0 0.0 12 5.0 0.0 2.7 3 1 0 3 3 2 0 NB-ARC domain FtsK_SpoIIIE PF01580.18 EWM28267.1 - 0.045 13.1 0.2 12 5.1 0.0 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family ATPase_2 PF01637.18 EWM28267.1 - 0.058 13.3 0.1 5.8 6.8 0.1 2.6 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EWM28267.1 - 0.06 13.4 0.0 3.4 7.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 EWM28267.1 - 0.079 12.2 0.0 4.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Septin AAA_25 PF13481.6 EWM28267.1 - 0.082 12.5 0.2 2.2 7.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain SRPRB PF09439.10 EWM28267.1 - 0.085 12.3 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit KTI12 PF08433.10 EWM28267.1 - 0.11 11.9 0.0 1.6 8.1 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_28 PF13521.6 EWM28267.1 - 0.12 12.6 0.0 8.2 6.6 0.0 2.9 2 1 1 3 3 3 0 AAA domain AAA_29 PF13555.6 EWM28267.1 - 0.14 12.0 0.0 19 5.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_33 PF13671.6 EWM28267.1 - 0.15 12.3 0.0 10 6.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 EWM28267.1 - 0.17 12.3 0.0 8.9 6.7 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 EWM28267.1 - 0.29 10.8 0.0 22 4.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.23 EWM28268.1 - 8.2e-25 87.8 0.0 1.4e-24 87.0 0.0 1.4 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EWM28268.1 - 1.8e-05 24.8 0.0 5.5e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 EWM28268.1 - 0.011 15.1 0.8 0.18 11.1 0.0 2.4 2 0 0 2 2 2 0 AIG1 family NAPRTase_C PF17956.1 EWM28268.1 - 0.078 13.4 1.0 0.56 10.7 0.0 2.7 3 0 0 3 3 3 0 Nicotinate phosphoribosyltransferase C-terminal domain AAA_16 PF13191.6 EWM28268.1 - 0.19 12.1 0.7 5.5 7.3 0.0 3.2 3 2 0 3 3 3 0 AAA ATPase domain AAA_23 PF13476.6 EWM28268.1 - 0.22 12.0 2.3 0.55 10.7 0.3 2.6 2 1 1 3 3 3 0 AAA domain Aa_trans PF01490.18 EWM28269.1 - 1.9e-05 23.6 9.0 9.7e-05 21.2 2.3 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EWM28269.1 - 0.012 14.7 0.5 0.012 14.7 0.5 2.1 2 0 0 2 2 2 0 Tryptophan/tyrosine permease family PNP_UDP_1 PF01048.20 EWM28270.1 - 1.4e-26 93.2 0.0 2.4e-26 92.5 0.0 1.4 1 1 0 1 1 1 1 Phosphorylase superfamily GYR PF02756.14 EWM28270.1 - 0.055 13.2 2.4 0.15 11.8 2.4 1.8 1 0 0 1 1 1 0 GYR motif Arginosuc_synth PF00764.19 EWM28271.1 - 3.7e-155 517.0 0.0 4.3e-155 516.8 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 EWM28271.1 - 0.042 13.4 0.0 0.086 12.3 0.0 1.5 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC DUF4427 PF14468.6 EWM28271.1 - 0.081 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4427) PDZ_6 PF17820.1 EWM28272.1 - 3.8e-07 29.9 0.0 1.3e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EWM28272.1 - 0.00012 22.4 0.2 0.00034 20.9 0.2 1.8 1 0 0 1 1 1 1 PDZ domain DUF3168 PF11367.8 EWM28272.1 - 0.031 14.5 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3168) ARL17 PF15840.5 EWM28272.1 - 0.99 9.8 4.1 9.7 6.6 0.3 3.3 3 0 0 3 3 3 0 ADP-ribosylation factor-like protein 17 MPLKIP PF15502.6 EWM28273.1 - 7.2e-05 22.9 0.0 0.00016 21.8 0.0 1.7 1 0 0 1 1 1 1 M-phase-specific PLK1-interacting protein APH PF01636.23 EWM28274.1 - 1.8e-22 80.4 0.0 2.7e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EWM28274.1 - 5e-08 32.8 0.5 2.9e-06 27.0 0.1 2.2 2 0 0 2 2 2 2 Choline/ethanolamine kinase EcKinase PF02958.20 EWM28274.1 - 0.009 15.4 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Methyltransf_23 PF13489.6 EWM28276.1 - 3.7e-18 65.9 0.0 5.1e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM28276.1 - 1.7e-15 57.4 0.0 2.6e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM28276.1 - 1.6e-14 54.4 0.0 2.7e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EWM28276.1 - 2.1e-14 54.1 0.0 3e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EWM28276.1 - 4.6e-12 45.8 0.0 6.3e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EWM28276.1 - 1.4e-10 41.1 0.0 1.9e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EWM28276.1 - 0.0011 18.8 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 EWM28276.1 - 0.0012 18.2 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_8 PF05148.15 EWM28276.1 - 0.0028 17.6 0.1 0.0097 15.8 0.0 1.8 2 1 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_24 PF13578.6 EWM28276.1 - 0.018 16.0 0.0 0.035 15.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EWM28276.1 - 0.025 13.8 0.0 0.12 11.5 0.0 1.8 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family DUF938 PF06080.12 EWM28276.1 - 0.085 12.6 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Ribosomal_L20 PF00453.18 EWM28277.1 - 1.5e-42 144.1 3.7 1.9e-42 143.7 3.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L20 Radical_SAM PF04055.21 EWM28279.1 - 3.3e-30 105.7 0.0 6.5e-30 104.7 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 EWM28279.1 - 8.3e-19 67.5 0.0 1.8e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 EWM28279.1 - 9.1e-06 25.6 0.0 2.3e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 TRAM domain FPN1 PF06963.12 EWM28280.1 - 6.2e-93 311.7 17.5 8.1e-93 311.3 17.5 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Insulin_TMD PF17870.1 EWM28280.1 - 2.2 8.4 3.9 3.5 7.8 0.4 2.8 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment DAHP_synth_2 PF01474.16 EWM28282.1 - 7e-129 430.1 0.0 7.8e-129 430.0 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Xan_ur_permease PF00860.20 EWM28284.1 - 4.6e-27 94.7 38.8 5.5e-27 94.5 38.8 1.0 1 0 0 1 1 1 1 Permease family MFS_MOT1 PF16983.5 EWM28284.1 - 0.013 15.9 10.4 0.013 15.9 10.4 3.2 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily Aa_trans PF01490.18 EWM28285.1 - 1.8e-30 106.0 0.0 4e-30 104.8 0.0 1.5 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Use1 PF09753.9 EWM28286.1 - 5e-23 82.1 0.0 6.3e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF2207 PF09972.9 EWM28286.1 - 0.19 10.4 0.2 0.26 10.0 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) KLRAQ PF10205.9 EWM28286.1 - 0.71 10.2 7.0 0.26 11.5 1.3 2.5 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein Fer2 PF00111.27 EWM28287.1 - 2.6e-09 36.9 4.0 4e-09 36.3 4.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Tim44 PF04280.15 EWM28288.1 - 0.00091 19.3 0.1 0.0031 17.6 0.1 1.8 2 0 0 2 2 2 1 Tim44-like domain Actin PF00022.19 EWM28289.1 - 3.1e-122 408.1 0.0 1.3e-121 406.1 0.0 1.7 1 1 0 1 1 1 1 Actin PseudoU_synth_2 PF00849.22 EWM28290.1 - 3.1e-26 92.4 0.2 3e-24 85.9 0.2 2.3 2 0 0 2 2 2 2 RNA pseudouridylate synthase FUSC PF04632.12 EWM28290.1 - 0.11 10.9 4.4 0.16 10.5 4.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DEK_C PF08766.11 EWM28291.1 - 0.0089 15.9 0.0 0.026 14.4 0.0 1.8 2 0 0 2 2 2 1 DEK C terminal domain N-SET PF11764.8 EWM28291.1 - 0.026 14.6 0.8 0.05 13.7 0.7 1.5 1 1 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N THUMP PF02926.17 EWM28292.1 - 3.7e-06 27.1 0.0 6.9e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 THUMP domain LysR_substrate PF03466.20 EWM28292.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 LysR substrate binding domain NiFe_hyd_SSU_C PF14720.6 EWM28293.1 - 0.1 13.0 0.3 0.6 10.5 0.1 2.1 2 0 0 2 2 2 0 NiFe/NiFeSe hydrogenase small subunit C-terminal Ribosomal_L6e PF01159.19 EWM28294.1 - 0.34 11.5 7.5 0.92 10.1 7.5 1.7 1 0 0 1 1 1 0 Ribosomal protein L6e FlaG PF03646.15 EWM28294.1 - 0.35 11.0 11.7 1.2 9.4 11.7 1.9 1 0 0 1 1 1 0 FlaG protein Phage_int_SAM_1 PF02899.17 EWM28295.1 - 0.00021 21.5 2.4 0.0036 17.6 0.3 3.1 3 0 0 3 3 3 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 EWM28295.1 - 0.00068 19.9 0.3 4 7.8 0.1 3.5 3 0 0 3 3 3 2 Phage integrase SAM-like domain Phage_int_SAM_4 PF13495.6 EWM28295.1 - 0.015 15.7 0.9 5.1 7.6 0.0 2.8 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_1 PF02899.17 EWM28296.1 - 0.00021 21.5 2.4 0.0036 17.6 0.3 3.1 3 0 0 3 3 3 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_5 PF13102.6 EWM28296.1 - 0.00068 19.9 0.3 4 7.8 0.1 3.5 3 0 0 3 3 3 2 Phage integrase SAM-like domain Phage_int_SAM_4 PF13495.6 EWM28296.1 - 0.015 15.7 0.9 5.1 7.6 0.0 2.8 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain HEAT PF02985.22 EWM28298.1 - 1.7e-09 37.1 11.9 0.021 15.0 0.0 7.8 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.6 EWM28298.1 - 1.1e-08 35.4 4.7 0.0076 16.6 0.1 5.4 4 1 0 5 5 5 2 HEAT repeats CLASP_N PF12348.8 EWM28298.1 - 0.00012 21.8 0.0 0.014 14.9 0.0 3.1 3 0 0 3 3 3 1 CLASP N terminal HEAT_EZ PF13513.6 EWM28298.1 - 0.0027 18.2 8.5 14 6.3 0.0 5.7 7 0 0 7 7 7 2 HEAT-like repeat ACDC PF14733.6 EWM28298.1 - 0.03 14.6 0.0 20 5.6 0.0 3.4 3 0 0 3 3 3 0 AP2-coincident C-terminal TPPII PF12580.8 EWM28299.1 - 2.1e-50 170.8 0.0 3.1e-50 170.3 0.0 1.2 1 0 0 1 1 1 1 Tripeptidyl peptidase II Bystin PF05291.11 EWM28300.1 - 2.1e-122 408.0 0.0 2.8e-122 407.6 0.0 1.2 1 0 0 1 1 1 1 Bystin ubiquitin PF00240.23 EWM28302.1 - 5.9e-20 70.8 0.0 1e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EWM28302.1 - 1.3e-05 24.9 0.0 1.3e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EWM28302.1 - 0.0015 19.0 1.1 0.0037 17.8 0.0 2.2 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain DUF5076 PF16826.5 EWM28302.1 - 0.0024 17.8 1.1 0.0039 17.1 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF5076) DUF2052 PF09747.9 EWM28302.1 - 0.018 15.2 3.0 2.1 8.5 0.5 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Rad60-SLD_2 PF13881.6 EWM28302.1 - 0.084 13.0 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Tubulin PF00091.25 EWM28302.1 - 0.15 12.2 2.3 0.27 11.4 2.3 1.4 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain ubiquitin PF00240.23 EWM28303.1 - 6.6e-20 70.6 0.0 1.1e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EWM28303.1 - 1.5e-05 24.7 0.0 1.5e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EWM28303.1 - 0.0018 18.8 1.1 0.0041 17.7 0.0 2.1 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain DUF5076 PF16826.5 EWM28303.1 - 0.0027 17.6 1.1 0.0044 16.9 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF5076) DUF2052 PF09747.9 EWM28303.1 - 0.02 15.0 2.8 2.3 8.3 0.5 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Rad60-SLD_2 PF13881.6 EWM28303.1 - 0.094 12.8 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Tubulin PF00091.25 EWM28303.1 - 0.17 12.0 2.3 0.3 11.3 2.3 1.4 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain ELO PF01151.18 EWM28304.1 - 6.8e-67 225.6 11.2 8.7e-67 225.3 11.2 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family TPR_2 PF07719.17 EWM28305.1 - 8.2e-20 69.3 13.7 3.3e-05 23.7 0.1 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.28 EWM28305.1 - 1.7e-19 68.7 11.0 3.4e-06 26.6 0.1 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 EWM28305.1 - 8.1e-12 44.6 13.5 0.0056 16.3 0.2 6.0 3 2 3 6 6 6 4 TPR repeat TPR_12 PF13424.6 EWM28305.1 - 2.8e-09 37.1 7.6 0.0014 18.9 1.8 4.4 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EWM28305.1 - 6.3e-09 35.3 10.7 0.012 15.8 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 EWM28305.1 - 3e-08 34.2 30.1 0.00093 19.8 3.1 5.8 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 EWM28305.1 - 8.7e-08 32.2 20.6 0.00079 19.5 0.0 6.1 4 1 3 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 EWM28305.1 - 9.5e-08 31.9 1.8 2.9 8.5 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EWM28305.1 - 2.3e-07 30.4 5.6 0.14 12.2 0.0 5.3 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 EWM28305.1 - 1.7e-05 24.5 16.3 0.0009 19.0 0.3 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 EWM28305.1 - 7.7e-05 23.1 12.8 1 10.1 0.2 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat BTAD PF03704.17 EWM28305.1 - 0.022 15.2 0.2 0.022 15.2 0.2 2.9 2 1 0 3 3 2 0 Bacterial transcriptional activator domain DUF3856 PF12968.7 EWM28305.1 - 0.059 13.4 1.3 0.39 10.8 0.4 2.7 2 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_4 PF07721.14 EWM28305.1 - 0.067 13.8 6.3 17 6.4 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 EWM28305.1 - 0.067 14.0 27.3 1.2 10.2 0.1 7.2 4 2 4 8 8 7 0 Tetratricopeptide repeat SAM_KSR1 PF13543.6 EWM28305.1 - 0.067 13.3 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 TPR_19 PF14559.6 EWM28305.1 - 0.14 12.7 0.2 0.14 12.7 0.2 4.4 2 1 4 6 6 5 0 Tetratricopeptide repeat Thioredoxin PF00085.20 EWM28306.1 - 4e-19 68.5 0.0 5.1e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EWM28306.1 - 0.0001 22.7 0.0 0.00021 21.7 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 EWM28306.1 - 0.0017 18.3 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 EWM28306.1 - 0.0042 16.8 0.0 0.0048 16.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 EWM28306.1 - 0.0074 16.0 0.0 0.0094 15.7 0.0 1.3 1 0 0 1 1 1 1 Redoxin Glutaredoxin PF00462.24 EWM28306.1 - 0.0095 16.1 0.0 0.014 15.6 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Plavaka PF18759.1 EWM28306.1 - 0.04 13.2 0.0 0.049 12.9 0.0 1.1 1 0 0 1 1 1 0 Plavaka transposase HyaE PF07449.11 EWM28306.1 - 0.099 12.6 0.0 0.22 11.5 0.0 1.7 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.6 EWM28306.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_8 PF13905.6 EWM28306.1 - 0.11 12.9 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like GARS_A PF01071.19 EWM28309.1 - 9.1e-65 218.1 0.0 1.3e-64 217.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Formyl_trans_N PF00551.19 EWM28309.1 - 4.7e-33 114.4 0.0 1.1e-32 113.3 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase GARS_N PF02844.15 EWM28309.1 - 3.9e-29 101.3 0.0 1.1e-28 99.8 0.0 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 EWM28309.1 - 8.8e-18 64.4 2.3 1.8e-17 63.4 0.3 2.7 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, C domain CPSase_L_D2 PF02786.17 EWM28309.1 - 5.9e-07 29.2 0.1 2.2e-06 27.3 0.1 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 EWM28309.1 - 0.00013 21.6 0.0 0.00022 20.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 EWM28309.1 - 0.0014 18.3 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain FIST PF08495.10 EWM28309.1 - 0.0028 17.7 1.3 3.6 7.6 0.1 3.4 3 1 1 4 4 4 1 FIST N domain ATP-grasp_3 PF02655.14 EWM28309.1 - 0.018 15.1 0.0 0.04 14.0 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_2 PF08442.10 EWM28309.1 - 0.024 14.2 0.0 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain RimK PF08443.11 EWM28309.1 - 0.025 14.2 0.0 0.049 13.2 0.0 1.5 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Cpn10 PF00166.21 EWM28310.1 - 9.7e-28 96.1 0.0 1.3e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Prp31_C PF09785.9 EWM28311.1 - 1.4e-09 38.9 0.2 2e-09 38.4 0.2 1.2 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.18 EWM28312.1 - 3.5e-13 49.5 0.0 4.8e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 EWM28312.1 - 2e-11 44.8 6.7 2e-11 44.8 6.7 1.6 2 0 0 2 2 2 1 Prp31 C terminal domain RRM_1 PF00076.22 EWM28316.1 - 4.5e-17 61.6 0.0 7.7e-17 60.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EWM28316.1 - 3.1e-05 23.6 0.0 5.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S7 PF00177.21 EWM28318.1 - 2.3e-35 121.5 3.1 2.8e-35 121.2 3.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e PhyH PF05721.13 EWM28319.1 - 0.00014 22.2 0.0 0.0021 18.3 0.0 2.3 2 1 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) D-ser_dehydrat PF14031.6 EWM28319.1 - 0.089 13.5 0.0 0.21 12.2 0.0 1.7 1 0 0 1 1 1 0 Putative serine dehydratase domain FAD_binding_3 PF01494.19 EWM28320.1 - 1.2e-17 64.2 0.1 3.3e-10 39.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 EWM28320.1 - 5.4e-05 22.4 0.0 0.00012 21.3 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EWM28320.1 - 0.00015 21.5 0.0 0.00031 20.4 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EWM28320.1 - 0.0002 20.7 0.0 0.00034 19.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EWM28320.1 - 0.00025 21.2 0.1 0.00061 20.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EWM28320.1 - 0.0037 16.7 0.1 0.0052 16.2 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EWM28320.1 - 0.0053 16.0 0.0 0.0081 15.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EWM28320.1 - 0.011 14.9 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 EWM28320.1 - 0.013 14.2 0.0 0.021 13.6 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 EWM28320.1 - 0.061 12.2 0.0 0.083 11.7 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.22 EWM28320.1 - 0.082 12.0 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Glu_dehyd_C PF16912.5 EWM28320.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Pyr_redox PF00070.27 EWM28320.1 - 0.17 12.4 0.0 0.34 11.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase IGPS PF00218.21 EWM28323.1 - 7.9e-14 51.4 0.0 1.3e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase ADH_zinc_N PF00107.26 EWM28323.1 - 0.087 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ABC_membrane PF00664.23 EWM28324.1 - 4e-41 141.5 0.0 5e-41 141.2 0.0 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region BTD PF09270.10 EWM28324.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Beta-trefoil DNA-binding domain CAP_N PF01213.19 EWM28324.1 - 1.5 8.2 3.8 2.5 7.5 3.8 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal MMR_HSR1 PF01926.23 EWM28325.1 - 7e-42 142.1 0.3 3.2e-21 75.6 0.1 4.2 4 1 0 4 4 4 3 50S ribosome-binding GTPase KH_dom-like PF14714.6 EWM28325.1 - 4.4e-21 75.0 0.1 8.3e-21 74.1 0.1 1.5 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.18 EWM28325.1 - 1.8e-16 60.0 0.1 1.4e-07 31.2 0.0 3.7 3 0 0 3 3 3 3 Ferrous iron transport protein B GTP_EFTU PF00009.27 EWM28325.1 - 2.2e-14 53.5 0.0 2.4e-07 30.5 0.0 4.8 3 2 0 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EWM28325.1 - 5.8e-09 36.2 0.1 0.22 11.6 0.0 5.0 5 0 0 5 5 5 3 Dynamin family RsgA_GTPase PF03193.16 EWM28325.1 - 7.2e-06 26.0 0.0 0.44 10.4 0.1 4.2 4 0 0 4 4 4 1 RsgA GTPase Arf PF00025.21 EWM28325.1 - 4.6e-05 22.9 0.0 0.26 10.7 0.0 3.8 4 0 0 4 4 4 1 ADP-ribosylation factor family Roc PF08477.13 EWM28325.1 - 0.00018 21.7 0.1 0.56 10.4 0.0 4.3 4 0 0 4 4 4 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 EWM28325.1 - 0.00073 20.1 0.4 0.23 11.9 0.0 3.0 3 1 0 3 3 3 1 ABC transporter AAA_16 PF13191.6 EWM28325.1 - 0.00083 19.8 0.2 2.5 8.4 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain Ras PF00071.22 EWM28325.1 - 0.0061 16.2 0.0 7 6.2 0.0 3.8 4 1 0 4 4 4 1 Ras family cobW PF02492.19 EWM28325.1 - 0.015 14.9 0.7 0.43 10.1 0.0 3.4 4 0 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EWM28325.1 - 0.035 13.1 10.6 2.2 7.2 0.1 4.5 5 0 0 5 5 4 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 EWM28325.1 - 0.035 14.4 1.1 6.4 7.0 0.3 3.9 2 2 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EWM28325.1 - 0.099 12.4 0.0 12 5.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Atg14 PF10186.9 EWM28325.1 - 3.7 6.6 6.8 7.1 5.6 6.8 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_18 PF13238.6 EWM28325.1 - 4.6 7.8 6.9 20 5.8 0.0 4.0 4 2 0 4 4 3 0 AAA domain Pyrid_oxidase_2 PF13883.6 EWM28326.1 - 5e-13 49.4 0.0 1.1e-12 48.2 0.0 1.6 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF2470 PF10615.9 EWM28326.1 - 1.6e-12 47.9 0.2 3.5e-12 46.8 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Putative_PNPOx PF01243.20 EWM28326.1 - 1.4e-07 31.5 0.0 3.4e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase UBX PF00789.20 EWM28327.1 - 6.3e-13 48.7 0.0 1.3e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 EWM28327.1 - 8.8e-10 38.3 0.0 1.8e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UPF0242 PF06785.11 EWM28327.1 - 2.1 8.4 10.3 3.5 7.7 10.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus APH PF01636.23 EWM28327.1 - 2.7 7.9 9.4 5 7.0 9.4 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4746 PF15928.5 EWM28327.1 - 3.8 6.9 8.7 6.6 6.1 8.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Borrelia_P83 PF05262.11 EWM28327.1 - 4.7 5.6 9.0 6.6 5.1 9.0 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein SepSecS PF05889.13 EWM28329.1 - 9.2e-104 347.2 0.0 7.2e-42 143.5 0.0 3.4 3 1 0 3 3 3 3 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS SinI PF08671.10 EWM28329.1 - 0.027 14.3 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 Anti-repressor SinI DUF2002 PF09400.10 EWM28329.1 - 0.079 13.0 0.2 0.23 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2002) RAP1 PF07218.11 EWM28329.1 - 1.3 7.3 2.7 2.1 6.5 2.7 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) HgmA PF04209.13 EWM28330.1 - 1.3e-193 643.5 0.0 1.5e-193 643.3 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase HgmA PF04209.13 EWM28331.1 - 5.2e-119 397.7 0.0 6.6e-119 397.4 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase MtN3_slv PF03083.16 EWM28332.1 - 2.8e-24 85.0 9.4 9.1e-15 54.5 2.0 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange TMEM206 PF15122.6 EWM28332.1 - 0.073 12.2 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 TMEM206 protein family MtN3_slv PF03083.16 EWM28333.1 - 4.9e-23 81.0 7.9 8.9e-15 54.5 2.0 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange TMEM206 PF15122.6 EWM28333.1 - 0.074 12.2 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 TMEM206 protein family DUF2070 PF09843.9 EWM28333.1 - 9.1 4.4 9.4 13 3.9 9.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Mpv17_PMP22 PF04117.12 EWM28334.1 - 3.5e-13 49.6 0.0 6.4e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Itfg2 PF15907.5 EWM28335.1 - 3.8e-19 68.9 0.0 9.2e-10 38.1 0.0 3.9 3 1 0 3 3 3 3 Integrin-alpha FG-GAP repeat-containing protein 2 BBS2_Mid PF14783.6 EWM28335.1 - 3.2e-07 30.4 0.0 0.03 14.4 0.0 3.9 4 0 0 4 4 4 2 Ciliary BBSome complex subunit 2, middle region VCBS PF13517.6 EWM28335.1 - 2.8e-06 27.8 0.4 0.08 13.5 0.0 3.6 4 0 0 4 4 4 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 EWM28335.1 - 8e-06 25.9 2.4 0.096 12.8 0.3 2.9 2 0 0 2 2 2 2 FG-GAP repeat CoA_transf_3 PF02515.17 EWM28335.1 - 0.0095 15.1 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 CoA-transferase family III BBS1 PF14779.6 EWM28335.1 - 0.32 10.4 0.1 4.3 6.7 0.0 2.4 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 1 Nore1-SARAH PF16517.5 EWM28336.1 - 0.63 10.0 2.7 0.51 10.3 0.4 2.1 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain AAA_16 PF13191.6 EWM28338.1 - 2.5e-06 28.0 0.0 5.1e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 EWM28338.1 - 4e-05 23.3 0.1 0.0096 15.5 0.0 2.6 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 EWM28338.1 - 0.00013 22.5 0.2 0.00039 21.0 0.0 1.8 1 1 1 2 2 2 1 ABC transporter AAA_22 PF13401.6 EWM28338.1 - 0.0002 21.6 0.0 0.00097 19.4 0.0 2.0 1 1 1 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EWM28338.1 - 0.0012 18.9 0.0 0.0044 17.1 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Rad17 PF03215.15 EWM28338.1 - 0.0013 18.7 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain ATPase_2 PF01637.18 EWM28338.1 - 0.0015 18.5 0.0 0.0031 17.5 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EWM28338.1 - 0.0016 18.4 0.0 0.0042 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 EWM28338.1 - 0.002 17.4 0.0 0.0026 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA PF00004.29 EWM28338.1 - 0.002 18.5 0.0 0.0046 17.4 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EWM28338.1 - 0.0022 17.9 0.1 0.0071 16.3 0.0 1.9 1 1 1 2 2 2 1 RsgA GTPase Zeta_toxin PF06414.12 EWM28338.1 - 0.0025 17.1 2.8 0.19 11.0 0.0 2.3 1 1 1 2 2 2 1 Zeta toxin RNA_helicase PF00910.22 EWM28338.1 - 0.0028 18.0 0.0 0.0074 16.7 0.0 1.7 2 0 0 2 2 1 1 RNA helicase AAA_33 PF13671.6 EWM28338.1 - 0.0042 17.2 1.6 0.0079 16.4 0.1 2.3 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 EWM28338.1 - 0.0078 16.1 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_28 PF13521.6 EWM28338.1 - 0.0079 16.4 0.6 0.033 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EWM28338.1 - 0.0099 15.6 0.0 0.024 14.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 EWM28338.1 - 0.012 15.4 0.0 1.6 8.5 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 EWM28338.1 - 0.012 16.1 0.7 0.064 13.8 0.0 2.3 3 0 0 3 3 3 0 AAA domain Adeno_IVa2 PF02456.15 EWM28338.1 - 0.014 14.2 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_5 PF07728.14 EWM28338.1 - 0.033 14.2 0.1 0.097 12.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 EWM28338.1 - 0.037 13.6 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 EWM28338.1 - 0.042 13.6 0.0 0.24 11.1 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Viral_helicase1 PF01443.18 EWM28338.1 - 0.05 13.3 1.0 0.068 12.9 0.1 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase CLP1_P PF16575.5 EWM28338.1 - 0.06 13.1 0.6 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop SRP54 PF00448.22 EWM28338.1 - 0.07 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_29 PF13555.6 EWM28338.1 - 0.1 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EWM28338.1 - 0.11 13.0 1.2 0.38 11.2 0.0 2.1 1 1 1 2 2 2 0 AAA domain NTPase_1 PF03266.15 EWM28338.1 - 0.17 11.8 0.4 0.49 10.3 0.1 1.9 2 0 0 2 2 2 0 NTPase AAA_11 PF13086.6 EWM28338.1 - 2.5 7.8 7.5 1.5 8.5 0.1 2.1 1 1 1 2 2 2 0 AAA domain Spt4 PF06093.13 EWM28342.1 - 1e-23 83.2 0.1 2.2e-23 82.2 0.1 1.6 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger CDC27 PF09507.10 EWM28342.1 - 0.44 9.9 24.3 0.58 9.5 24.3 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 LAP1C PF05609.12 EWM28342.1 - 0.74 8.8 15.1 0.87 8.6 15.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Raftlin PF15250.6 EWM28342.1 - 1.4 7.5 12.5 1.6 7.4 12.5 1.2 1 0 0 1 1 1 0 Raftlin DUF262 PF03235.14 EWM28342.1 - 1.5 8.9 7.2 2 8.5 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 RecQ_Zn_bind PF16124.5 EWM28342.1 - 1.8 9.4 7.0 5.6 7.8 7.0 2.0 1 1 0 1 1 1 0 RecQ zinc-binding Presenilin PF01080.17 EWM28342.1 - 2.6 6.7 18.1 2.8 6.6 18.1 1.1 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 EWM28342.1 - 3.1 5.8 14.7 3.6 5.6 14.7 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SLC12 PF03522.15 EWM28342.1 - 6.7 5.6 10.8 8.1 5.3 10.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 YidD PF01809.18 EWM28345.1 - 1.4e-24 85.7 0.0 2.4e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 Putative membrane protein insertion efficiency factor Fapy_DNA_glyco PF01149.24 EWM28346.1 - 0.1 13.2 0.0 0.14 12.8 0.0 1.2 1 0 0 1 1 1 0 Formamidopyrimidine-DNA glycosylase N-terminal domain TPR_11 PF13414.6 EWM28347.1 - 5.7e-07 29.1 0.0 0.00021 20.9 0.0 2.2 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 EWM28347.1 - 0.00027 20.9 0.0 0.48 10.8 0.0 3.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EWM28347.1 - 0.00051 20.0 0.0 0.13 12.4 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EWM28347.1 - 0.00089 19.5 0.0 0.21 12.0 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EWM28347.1 - 0.0038 17.7 0.0 0.01 16.4 0.0 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 EWM28347.1 - 0.011 15.9 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 EWM28347.1 - 0.02 15.7 0.0 11 7.2 0.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EWM28347.1 - 0.059 13.2 0.0 3.8 7.5 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EWM28347.1 - 0.099 13.3 0.0 2.3 8.9 0.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF4192 PF13830.6 EWM28347.1 - 0.14 12.2 0.0 0.27 11.2 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4192) TPR_1 PF00515.28 EWM28348.1 - 0.013 15.3 0.3 0.013 15.3 0.3 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EWM28348.1 - 0.02 15.0 1.5 0.026 14.6 0.4 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Thr_synth_N PF14821.6 EWM28349.1 - 2.3e-18 66.2 0.0 1.2e-17 63.9 0.0 2.1 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 EWM28349.1 - 4.3e-07 29.6 0.5 2e-05 24.1 0.0 2.0 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme F-box PF00646.33 EWM28350.1 - 5.6e-05 22.9 1.5 0.00014 21.6 1.5 1.7 1 0 0 1 1 1 1 F-box domain IceA2 PF05862.11 EWM28358.1 - 0.014 15.3 0.1 0.024 14.6 0.1 1.4 1 0 0 1 1 1 0 Helicobacter pylori IceA2 protein Pec_lyase_C PF00544.19 EWM28358.1 - 0.078 12.5 0.0 0.081 12.5 0.0 1.1 1 0 0 1 1 1 0 Pectate lyase DUF1232 PF06803.12 EWM28359.1 - 0.29 10.9 1.6 4.8 7.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1232) NuA4 PF09340.10 EWM28361.1 - 9.6e-14 51.0 0.1 2.3e-13 49.8 0.0 1.6 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 SUIM_assoc PF16619.5 EWM28361.1 - 0.063 13.4 0.0 0.15 12.1 0.0 1.6 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF1843 PF08898.10 EWM28361.1 - 0.19 12.3 0.8 0.33 11.5 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) GNAT_like PF18407.1 EWM28362.1 - 0.036 14.4 0.4 0.036 14.4 0.4 1.8 2 0 0 2 2 2 0 GCN5-related N-acetyltransferase like domain DUF1738 PF08401.11 EWM28364.1 - 0.00043 20.4 0.7 0.00072 19.7 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1738) Prothymosin PF03247.14 EWM28364.1 - 0.014 15.9 10.7 0.014 15.9 10.7 2.7 3 0 0 3 3 3 0 Prothymosin/parathymosin family DNA_pol_phi PF04931.13 EWM28364.1 - 0.035 12.2 3.4 0.041 12.0 3.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF4746 PF15928.5 EWM28364.1 - 0.082 12.3 2.6 0.11 11.8 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Pox_Ag35 PF03286.14 EWM28364.1 - 0.095 12.5 0.6 0.15 11.8 0.6 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PBP1_TM PF14812.6 EWM28364.1 - 0.29 11.5 5.0 0.66 10.4 5.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.14 EWM28364.1 - 0.41 8.9 3.2 0.51 8.6 3.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EWM28364.1 - 0.54 8.4 6.1 0.67 8.1 6.1 1.1 1 0 0 1 1 1 0 Nop14-like family RPA43_OB PF17875.1 EWM28364.1 - 0.56 10.8 3.6 0.94 10.1 3.6 1.3 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Paf1 PF03985.13 EWM28364.1 - 1.6 7.6 8.2 2.3 7.1 8.2 1.2 1 0 0 1 1 1 0 Paf1 LMBR1 PF04791.16 EWM28367.1 - 1.1e-11 44.4 0.4 1.4e-11 44.0 0.4 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein PH PF00169.29 EWM28367.1 - 3.1e-06 27.7 0.4 6.1e-06 26.7 0.2 1.5 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 EWM28367.1 - 0.045 14.0 0.1 0.083 13.2 0.1 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain PH_2 PF08458.10 EWM28367.1 - 0.057 13.8 0.5 0.12 12.7 0.5 1.5 1 0 0 1 1 1 0 Plant pleckstrin homology-like region PH_11 PF15413.6 EWM28367.1 - 0.17 12.3 0.9 0.68 10.4 0.9 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain ubiquitin PF00240.23 EWM28370.1 - 0.013 15.3 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family DUF2407 PF10302.9 EWM28370.1 - 0.039 14.5 0.0 0.069 13.7 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Asparaginase_2 PF01112.18 EWM28374.1 - 1.7e-69 234.2 1.7 1e-66 225.1 0.1 2.1 1 1 1 2 2 2 2 Asparaginase zf-MYND PF01753.18 EWM28375.1 - 3.7e-07 30.1 10.4 6.7e-07 29.3 10.4 1.5 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 EWM28376.1 - 4.3e-07 29.9 10.4 7.9e-07 29.1 10.4 1.5 1 0 0 1 1 1 1 MYND finger HA2 PF04408.23 EWM28378.1 - 6.4e-21 74.7 0.0 7.2e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Helicase associated domain (HA2) DUF3146 PF11344.8 EWM28378.1 - 0.2 11.4 0.2 0.55 9.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3146) PH PF00169.29 EWM28382.1 - 0.0023 18.4 0.1 0.0031 18.0 0.1 1.2 1 0 0 1 1 1 1 PH domain Ion_trans PF00520.31 EWM28383.1 - 2.5e-28 98.9 1.9 3.3e-28 98.6 1.9 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EWM28383.1 - 2.1e-10 40.4 2.0 2.1e-10 40.4 2.0 2.8 2 1 0 2 2 2 1 Ion channel Ion_trans PF00520.31 EWM28384.1 - 2.5e-28 99.0 1.2 3.4e-28 98.5 1.2 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EWM28384.1 - 2.6e-10 40.1 1.9 2.6e-10 40.1 1.9 2.7 2 1 0 2 2 2 1 Ion channel DUF1772 PF08592.11 EWM28384.1 - 0.0047 17.3 0.3 0.02 15.2 0.0 2.3 2 2 1 3 3 3 1 Domain of unknown function (DUF1772) IncFII_repA PF02387.15 EWM28384.1 - 0.023 13.9 0.5 0.035 13.4 0.5 1.2 1 0 0 1 1 1 0 IncFII RepA protein family Mt_ATP-synt_D PF05873.12 EWM28384.1 - 0.083 12.7 4.7 0.13 12.2 4.7 1.2 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) FAM165 PF14981.6 EWM28384.1 - 1.1 9.1 3.1 3.5 7.5 3.1 1.9 1 0 0 1 1 1 0 FAM165 family Ion_trans PF00520.31 EWM28385.1 - 2.5e-28 98.9 1.9 3.3e-28 98.6 1.9 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EWM28385.1 - 2.1e-10 40.4 2.0 2.1e-10 40.4 2.0 2.8 2 1 0 2 2 2 1 Ion channel Methyltr_RsmB-F PF01189.17 EWM28387.1 - 1.7e-28 99.7 0.0 1.1e-13 51.3 0.0 2.4 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F PUA PF01472.20 EWM28387.1 - 5.4e-05 23.1 0.1 0.00011 22.0 0.1 1.5 1 0 0 1 1 1 1 PUA domain FtsJ PF01728.19 EWM28387.1 - 0.0083 16.2 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltr_RsmF_N PF17125.5 EWM28387.1 - 0.12 12.9 0.1 0.2 12.1 0.1 1.3 1 0 0 1 1 1 0 N-terminal domain of 16S rRNA methyltransferase RsmF SET PF00856.28 EWM28390.1 - 2.3e-08 34.6 0.0 0.02 15.2 0.0 3.6 2 2 0 2 2 2 2 SET domain LZ_Tnp_IS66 PF13007.7 EWM28390.1 - 0.32 11.8 4.3 0.42 11.4 0.5 2.4 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain Ferlin_C PF16165.5 EWM28390.1 - 1.6 8.7 4.8 0.9 9.5 0.6 2.1 2 0 0 2 2 2 0 Ferlin C-terminus ABC2_membrane PF01061.24 EWM28391.1 - 2.6e-17 62.9 19.3 2.9e-17 62.8 19.3 1.0 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 EWM28391.1 - 0.078 12.1 15.9 0.087 11.9 15.9 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein Exo_endo_phos PF03372.23 EWM28392.1 - 0.041 13.4 0.1 0.097 12.2 0.0 1.7 2 0 0 2 2 2 0 Endonuclease/Exonuclease/phosphatase family TP53IP5 PF15331.6 EWM28392.1 - 0.36 11.0 3.7 0.64 10.1 3.7 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 SDA1 PF05285.12 EWM28392.1 - 0.96 8.8 27.2 1.5 8.2 27.2 1.1 1 0 0 1 1 1 0 SDA1 Lin-8 PF03353.15 EWM28392.1 - 3 7.3 15.5 4.4 6.8 15.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TFIIF_alpha PF05793.12 EWM28392.1 - 7.1 5.1 26.7 10 4.6 26.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC27 PF09507.10 EWM28392.1 - 8.8 5.6 21.2 13 5.0 21.2 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Glyco_hydro_8 PF01270.17 EWM28394.1 - 2.3e-25 89.2 6.2 3.4e-25 88.6 6.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 8 CASP_C PF08172.12 EWM28396.1 - 1.9e-57 194.5 0.1 3.1e-57 193.8 0.0 1.3 1 1 0 1 1 1 1 CASP C terminal Golgin_A5 PF09787.9 EWM28396.1 - 0.0017 17.9 0.4 0.0017 17.9 0.4 2.4 2 1 0 3 3 3 1 Golgin subfamily A member 5 Rootletin PF15035.6 EWM28396.1 - 0.042 13.9 1.8 0.093 12.7 0.4 2.0 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion SlyX PF04102.12 EWM28396.1 - 0.13 12.9 0.5 26 5.5 0.7 2.8 3 0 0 3 3 3 0 SlyX CEP209_CC5 PF16574.5 EWM28396.1 - 0.34 11.1 3.7 9.5 6.4 0.1 2.4 2 0 0 2 2 2 0 Coiled-coil region of centrosome protein CE290 ABC_tran_CTD PF16326.5 EWM28396.1 - 0.56 10.5 4.4 1.3 9.4 0.6 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain DivIC PF04977.15 EWM28396.1 - 0.94 9.3 4.6 0.86 9.4 0.1 2.6 2 1 1 3 3 3 0 Septum formation initiator DUF4140 PF13600.6 EWM28396.1 - 4.2 7.9 6.3 19 5.8 0.5 2.7 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Sulfate_transp PF00916.20 EWM28397.1 - 2.3e-18 66.1 20.3 3.3e-18 65.6 20.3 1.2 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 EWM28397.1 - 7.7e-11 41.9 0.0 0.00025 21.1 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain STAS PF01740.21 EWM28397.1 - 6.4e-06 25.8 0.0 2.2e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 STAS domain Sulfate_transp PF00916.20 EWM28398.1 - 6.7e-18 64.6 10.0 1.1e-17 63.9 10.0 1.2 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 EWM28398.1 - 2.8e-11 43.3 0.2 0.00023 21.2 0.0 3.2 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain STAS PF01740.21 EWM28398.1 - 5.4e-06 26.0 0.0 1.9e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 STAS domain Sybindin PF04099.12 EWM28399.1 - 1.3e-22 80.2 0.0 2e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family RNA_pol_3_Rpc31 PF11705.8 EWM28402.1 - 1.6e-07 31.8 0.7 4e-07 30.5 0.7 1.8 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 RNA_pol_3_Rpc31 PF11705.8 EWM28403.1 - 2.3e-07 31.3 0.0 3.2e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 CD36 PF01130.21 EWM28404.1 - 1.3e-32 112.9 0.0 2.9e-18 65.7 0.0 2.4 2 1 0 2 2 2 2 CD36 family PBP1_TM PF14812.6 EWM28404.1 - 0.0032 17.8 1.0 0.006 16.9 1.0 1.4 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 EWM28404.1 - 1.2 8.8 6.5 2.2 7.9 6.5 1.4 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 EWM28404.1 - 1.7 7.9 15.6 2.6 7.3 15.6 1.1 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 EWM28404.1 - 5.6 7.0 9.3 10 6.1 9.3 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal PBP PF01161.20 EWM28405.1 - 1.2e-16 61.2 0.0 1.6e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein zf-UBP PF02148.19 EWM28406.1 - 1.1e-13 51.3 2.0 4.2e-13 49.4 2.0 1.9 1 1 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein IF3_N PF05198.16 EWM28407.1 - 7e-16 58.3 0.1 1.4e-15 57.3 0.1 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain IF3_C PF00707.22 EWM28407.1 - 4.9e-06 26.4 0.0 9e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain ABC_tran PF00005.27 EWM28408.1 - 1.5e-41 142.2 0.0 2.6e-26 92.8 0.0 3.9 3 1 0 3 3 3 3 ABC transporter ABC_membrane PF00664.23 EWM28408.1 - 1.3e-27 97.2 15.9 1.8e-26 93.4 8.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EWM28408.1 - 2e-07 30.7 0.0 0.041 13.3 0.0 3.2 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EWM28408.1 - 0.0037 17.3 0.2 0.058 13.5 0.1 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.6 EWM28408.1 - 0.017 14.9 0.0 0.76 9.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 EWM28408.1 - 0.029 14.3 1.6 3.3 7.6 0.1 3.1 3 0 0 3 3 3 0 Rad17 P-loop domain CsgG PF03783.14 EWM28408.1 - 0.048 12.9 1.6 0.14 11.5 1.6 1.7 1 0 0 1 1 1 0 Curli production assembly/transport component CsgG AAA_16 PF13191.6 EWM28408.1 - 0.12 12.7 0.0 0.5 10.7 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.17 EWM28408.1 - 0.13 12.3 0.1 0.26 11.4 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 EWM28408.1 - 0.23 11.2 0.8 1.3 8.9 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Phage_holin_3_6 PF07332.11 EWM28408.1 - 3.2 7.8 7.6 14 5.7 2.4 3.0 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Abhydrolase_1 PF00561.20 EWM28409.1 - 7.7e-09 35.6 0.8 7.2e-06 25.8 0.1 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EWM28409.1 - 2.8e-08 34.6 2.3 2.8e-08 34.6 1.2 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EWM28409.1 - 0.0066 16.0 0.0 0.024 14.1 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EWM28409.1 - 0.0073 15.6 0.3 0.027 13.7 0.1 2.0 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_8 PF06259.12 EWM28409.1 - 0.0087 15.7 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase BAAT_C PF08840.11 EWM28409.1 - 0.085 12.8 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 EWM28409.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.20 EWM28410.1 - 7.7e-09 35.6 0.8 7.2e-06 25.8 0.1 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EWM28410.1 - 2.8e-08 34.6 2.3 2.8e-08 34.6 1.2 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EWM28410.1 - 0.0066 16.0 0.0 0.024 14.1 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EWM28410.1 - 0.0073 15.6 0.3 0.027 13.7 0.1 2.0 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_8 PF06259.12 EWM28410.1 - 0.0087 15.7 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase BAAT_C PF08840.11 EWM28410.1 - 0.085 12.8 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 EWM28410.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase CSN8_PSD8_EIF3K PF10075.9 EWM28412.1 - 3.7e-07 30.2 0.0 7.3e-07 29.3 0.0 1.4 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family ABC_membrane PF00664.23 EWM28413.1 - 2.6e-06 27.3 3.4 0.00012 21.8 0.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region DUF713 PF05218.14 EWM28415.1 - 0.012 15.4 4.3 0.012 15.4 4.3 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF713) ORF11CD3 PF10549.9 EWM28415.1 - 0.47 10.6 4.8 0.55 10.4 0.3 3.3 4 0 0 4 4 4 0 ORF11CD3 domain YlqD PF11068.8 EWM28415.1 - 1.8 8.9 41.9 0.82 10.0 5.2 4.1 2 1 2 4 4 4 0 YlqD protein Bacillus_HBL PF05791.11 EWM28415.1 - 4 7.2 9.2 11 5.8 0.1 3.6 3 1 1 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) DUF1664 PF07889.12 EWM28415.1 - 9.6 6.3 21.8 1.6 8.8 0.3 4.5 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) WD40 PF00400.32 EWM28416.1 - 7.5e-13 48.7 9.0 0.0045 17.8 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM28416.1 - 1.6e-06 28.4 0.1 4.2e-05 23.8 0.1 2.8 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EWM28416.1 - 0.0014 18.6 0.0 0.0084 16.0 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EWM28416.1 - 0.0023 16.6 0.0 0.054 12.1 0.0 2.1 2 0 0 2 2 2 1 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 EWM28416.1 - 0.022 13.7 0.4 0.042 12.8 0.4 1.4 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain ABC_membrane PF00664.23 EWM28417.1 - 2.6e-46 158.5 19.4 2.5e-29 102.8 9.5 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 EWM28417.1 - 4.1e-44 150.4 0.0 5.9e-28 98.1 0.0 2.8 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EWM28417.1 - 1.7e-09 37.4 0.1 0.14 11.5 0.0 4.2 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EWM28417.1 - 1.4e-06 27.9 1.7 0.0094 15.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EWM28417.1 - 2.5e-06 27.5 0.2 0.12 12.1 0.0 3.5 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EWM28417.1 - 1.2e-05 25.3 0.4 0.0096 16.0 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase MeaB PF03308.16 EWM28417.1 - 4.1e-05 22.7 0.7 0.091 11.7 0.2 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 EWM28417.1 - 0.00013 22.4 0.3 0.22 11.9 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 EWM28417.1 - 0.00095 19.7 4.9 0.1 13.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 EWM28417.1 - 0.0017 18.6 2.8 1.8 8.9 0.1 3.3 3 0 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 EWM28417.1 - 0.0045 16.9 0.8 2.7 7.9 0.3 2.4 2 0 0 2 2 2 2 RsgA GTPase T2SSE PF00437.20 EWM28417.1 - 0.0069 15.5 0.3 0.12 11.5 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_18 PF13238.6 EWM28417.1 - 0.0069 16.9 0.1 6 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EWM28417.1 - 0.011 15.3 1.8 0.24 11.0 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 EWM28417.1 - 0.017 14.4 0.1 5.4 6.2 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.15 EWM28417.1 - 0.02 14.8 0.1 2.8 7.8 0.0 2.4 2 0 0 2 2 2 0 NTPase MobB PF03205.14 EWM28417.1 - 0.026 14.4 0.2 6.2 6.7 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.22 EWM28417.1 - 0.029 13.5 2.3 0.57 9.3 0.2 2.7 3 0 0 3 3 3 0 NB-ARC domain NACHT PF05729.12 EWM28417.1 - 0.035 14.0 1.2 2.5 8.0 0.1 2.9 3 0 0 3 3 2 0 NACHT domain AAA_25 PF13481.6 EWM28417.1 - 0.039 13.5 0.5 7.4 6.1 0.1 2.6 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 EWM28417.1 - 0.054 13.3 0.2 11 5.7 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 EWM28417.1 - 0.055 13.6 0.0 11 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EWM28417.1 - 0.058 13.1 0.6 0.78 9.4 0.2 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 EWM28417.1 - 0.061 12.8 0.1 2.4 7.6 0.1 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF87 PF01935.17 EWM28417.1 - 0.065 13.3 0.4 0.48 10.5 0.1 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain DUF815 PF05673.13 EWM28417.1 - 0.069 12.3 0.0 3.4 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA PF00004.29 EWM28417.1 - 0.081 13.3 0.3 19 5.7 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EWM28417.1 - 0.18 11.8 0.2 31 4.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EWM28417.1 - 0.2 12.1 0.1 3.7 8.0 0.1 2.4 2 0 0 2 2 2 0 RNA helicase Rad17 PF03215.15 EWM28417.1 - 0.21 11.5 0.2 27 4.6 0.1 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain PduV-EutP PF10662.9 EWM28417.1 - 0.24 11.2 1.5 3.4 7.4 0.2 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 EWM28417.1 - 0.4 10.7 2.0 25 4.9 0.1 2.6 2 0 0 2 2 2 0 Dynamin family AMPK1_CBM PF16561.5 EWM28418.1 - 4e-32 110.3 0.5 6.3e-32 109.7 0.5 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 EWM28418.1 - 7.1e-23 80.7 1.9 1.2e-22 79.9 1.9 1.3 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM_48 PF02922.18 EWM28418.1 - 0.07 13.5 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) DUF4795 PF16043.5 EWM28419.1 - 3.6 7.1 11.6 1.3 8.6 0.4 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4795) AAA_5 PF07728.14 EWM28421.1 - 1.8e-24 86.3 0.0 1.6e-23 83.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EWM28421.1 - 1.1e-05 25.3 0.0 3.4e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_6 PF12774.7 EWM28421.1 - 0.00012 21.2 0.0 0.0028 16.7 0.0 2.6 2 1 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region AAA_16 PF13191.6 EWM28421.1 - 0.00022 21.6 0.4 0.00065 20.1 0.4 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 EWM28421.1 - 0.00075 19.7 0.0 0.0015 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EWM28421.1 - 0.00082 19.4 0.0 0.003 17.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EWM28421.1 - 0.00084 19.6 0.0 0.0013 19.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EWM28421.1 - 0.0022 17.4 0.3 0.24 10.8 0.2 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EWM28421.1 - 0.0026 17.7 0.0 0.0043 17.0 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dynein_heavy PF03028.15 EWM28421.1 - 0.0042 17.2 0.0 0.008 16.3 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain AAA PF00004.29 EWM28421.1 - 0.014 15.8 0.0 0.046 14.1 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EWM28421.1 - 0.031 14.6 0.2 2.1 8.6 0.4 3.0 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EWM28421.1 - 0.035 14.7 0.0 0.06 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EWM28421.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein dNK PF01712.19 EWM28421.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase CPT PF07931.12 EWM28421.1 - 0.16 11.8 0.0 2.8 7.7 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Kinesin PF00225.23 EWM28422.1 - 1.4e-20 73.5 0.0 1.4e-20 73.5 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain Mcp5_PH PF12814.7 EWM28422.1 - 0.033 14.3 0.0 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology Kinesin PF00225.23 EWM28423.1 - 7.7e-37 127.0 0.6 1.1e-36 126.5 0.0 1.4 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EWM28423.1 - 1.3e-23 83.6 0.0 1.8e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding PIF1 PF05970.14 EWM28423.1 - 0.073 12.2 0.3 0.13 11.4 0.3 1.3 1 0 0 1 1 1 0 PIF1-like helicase DUF707 PF05212.12 EWM28424.1 - 2.4e-31 109.1 3.5 1.2e-25 90.5 0.2 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF707) DUF3381 PF11861.8 EWM28425.1 - 3.4 7.4 7.4 5.8 6.7 7.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3381) Mak10 PF04112.13 EWM28426.1 - 4.9e-26 91.2 0.4 4.4e-24 84.9 0.0 3.2 2 2 0 2 2 2 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase L_biotic_typeA PF04604.13 EWM28426.1 - 0.17 11.8 0.1 0.4 10.6 0.1 1.6 1 0 0 1 1 1 0 Type-A lantibiotic eIF3_subunit PF08597.10 EWM28426.1 - 0.18 11.7 2.2 0.79 9.6 0.3 2.3 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit VWA_CoxE PF05762.14 EWM28427.1 - 7.7e-05 22.2 0.1 0.054 12.9 0.0 2.3 2 0 0 2 2 2 2 VWA domain containing CoxE-like protein VWA_2 PF13519.6 EWM28427.1 - 0.02 15.5 0.0 0.037 14.7 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain Totivirus_coat PF05518.11 EWM28427.1 - 8.2 4.3 6.5 5 5.0 4.7 1.5 1 1 1 2 2 2 0 Totivirus coat protein Flavodoxin_1 PF00258.25 EWM28428.1 - 3e-29 102.1 0.0 5e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 EWM28428.1 - 1.5e-20 73.7 0.0 2.4e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_3 PF12641.7 EWM28428.1 - 0.042 13.5 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin domain Flavodoxin_5 PF12724.7 EWM28428.1 - 0.1 12.8 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain Pro_isomerase PF00160.21 EWM28429.1 - 2.8e-51 173.9 0.0 3.6e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Yippee-Mis18 PF03226.14 EWM28430.1 - 9.6e-13 48.3 0.1 1.8e-12 47.4 0.1 1.4 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Spt20 PF12090.8 EWM28430.1 - 0.022 14.4 8.0 0.035 13.7 8.0 1.4 1 0 0 1 1 1 0 Spt20 family XdhC_CoxI PF02625.16 EWM28430.1 - 0.1 12.8 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 XdhC and CoxI family ATPase-cat_bd PF12156.8 EWM28430.1 - 0.24 12.2 0.1 0.24 12.2 0.1 2.7 2 0 0 2 2 2 0 Putative metal-binding domain of cation transport ATPase Drc1-Sld2 PF11719.8 EWM28430.1 - 0.33 10.4 10.9 1.8 8.0 6.4 2.0 2 0 0 2 2 2 0 DNA replication and checkpoint protein BUD22 PF09073.10 EWM28430.1 - 0.4 10.0 19.2 0.57 9.5 19.2 1.2 1 0 0 1 1 1 0 BUD22 PIEZO PF15917.5 EWM28430.1 - 0.85 9.0 9.2 1.6 8.1 9.2 1.4 1 0 0 1 1 1 0 Piezo CSRNP_N PF16019.5 EWM28430.1 - 1.2 9.0 9.4 2.7 7.8 9.4 1.6 1 1 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus LAP1C PF05609.12 EWM28430.1 - 1.3 8.0 10.5 2 7.4 10.5 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SDA1 PF05285.12 EWM28430.1 - 1.4 8.3 22.1 2 7.8 22.1 1.1 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 EWM28430.1 - 6.6 4.7 21.8 9.7 4.1 21.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC27 PF09507.10 EWM28430.1 - 7 5.9 15.3 10 5.4 15.3 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TLD PF07534.16 EWM28431.1 - 5.1e-36 123.9 0.2 6.4e-36 123.6 0.2 1.1 1 0 0 1 1 1 1 TLD YqhR PF11085.8 EWM28433.1 - 0.57 10.1 3.7 0.39 10.6 2.0 1.6 1 1 0 1 1 1 0 Conserved membrane protein YqhR HGWP PF03578.15 EWM28434.1 - 0.1 12.1 0.3 0.2 11.2 0.3 1.4 1 0 0 1 1 1 0 HGWP repeat SNARE_assoc PF09335.11 EWM28436.1 - 9.2e-10 39.1 4.6 1.8e-05 25.2 0.1 2.8 3 0 0 3 3 2 2 SNARE associated Golgi protein GRP PF07172.11 EWM28436.1 - 0.0001 22.9 2.1 0.0001 22.9 2.1 3.1 4 0 0 4 4 4 1 Glycine rich protein family DUF2852 PF11014.8 EWM28436.1 - 0.087 13.0 0.0 8.6 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) DUF3357 PF11837.8 EWM28436.1 - 0.11 13.0 0.1 2.6 8.5 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) Abhydrolase_9_N PF15420.6 EWM28436.1 - 0.21 11.5 3.3 8.6 6.3 1.0 2.2 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Ninjurin PF04923.12 EWM28436.1 - 0.25 11.3 0.0 0.25 11.3 0.0 1.9 3 0 0 3 3 3 0 Ninjurin FtsL PF04999.13 EWM28436.1 - 0.35 10.9 1.3 4.9 7.2 0.2 2.4 2 0 0 2 2 2 0 Cell division protein FtsL DUF2207 PF09972.9 EWM28436.1 - 0.75 8.5 4.6 4.2 6.0 0.1 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DHHC PF01529.20 EWM28436.1 - 1.3 9.1 4.6 34 4.5 2.7 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF4131 PF13567.6 EWM28436.1 - 1.9 8.1 8.8 2.3 7.8 1.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) UPF0182 PF03699.13 EWM28436.1 - 2.9 5.9 3.9 2.1 6.4 0.7 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0182) mTERF PF02536.14 EWM28437.1 - 0.00084 18.4 0.0 0.0022 17.0 0.0 1.6 1 1 0 1 1 1 1 mTERF ABC2_membrane PF01061.24 EWM28438.1 - 2.4e-30 105.5 11.1 2.4e-30 105.5 11.1 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 EWM28438.1 - 4.7e-26 91.9 0.0 6.5e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EWM28438.1 - 1.4e-11 44.1 8.9 2.4e-11 43.3 8.9 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 EWM28438.1 - 1.2e-06 28.5 0.8 0.00016 21.6 0.0 2.2 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EWM28438.1 - 9.9e-05 22.3 0.1 0.00018 21.5 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 EWM28438.1 - 0.0046 17.5 0.1 0.0073 16.8 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EWM28438.1 - 0.01 16.3 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 EWM28438.1 - 0.011 15.2 0.0 0.26 10.7 0.0 2.0 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EWM28438.1 - 0.033 13.9 0.2 0.073 12.8 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 EWM28438.1 - 0.047 14.1 0.3 0.53 10.7 0.3 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 EWM28438.1 - 0.066 12.8 0.2 0.12 12.0 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 EWM28438.1 - 0.069 13.4 0.1 0.32 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 EWM28438.1 - 0.18 11.5 0.0 7.2 6.2 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.15 EWM28438.1 - 0.21 11.5 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain V-SNARE_C PF12352.8 EWM28439.1 - 1.8e-11 44.1 1.4 1.8e-11 44.1 1.4 1.8 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EWM28439.1 - 3.1e-06 27.0 0.1 7e-06 25.9 0.1 1.6 1 0 0 1 1 1 1 Sec20 CCDC106 PF15794.5 EWM28439.1 - 0.013 15.3 0.2 0.016 14.9 0.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF429 PF04250.13 EWM28439.1 - 0.014 15.2 1.2 0.027 14.3 1.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF429) TACC_C PF05010.14 EWM28439.1 - 0.12 12.2 0.3 1.3 8.7 0.3 2.0 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal PGK PF00162.19 EWM28439.1 - 0.16 10.9 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoglycerate kinase Mur_ligase_M PF08245.12 EWM28440.1 - 7.1e-10 39.2 0.0 2e-09 37.7 0.0 1.6 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 EWM28440.1 - 0.094 13.0 0.0 0.31 11.3 0.0 1.9 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain CENP-B_dimeris PF09026.10 EWM28440.1 - 0.12 12.8 0.8 0.27 11.7 0.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Form-deh_trans PF09163.11 EWM28440.1 - 3.6 7.5 4.6 11 5.9 4.6 1.8 1 0 0 1 1 1 0 Formate dehydrogenase N, transmembrane Paf1 PF03985.13 EWM28440.1 - 9.1 5.2 7.0 13 4.6 7.0 1.1 1 0 0 1 1 1 0 Paf1 AMP-binding PF00501.28 EWM28443.1 - 2.2e-24 85.8 0.0 2.4e-24 85.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 EWM28444.1 - 1.1e-11 44.0 0.1 1.3e-11 43.8 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme TMEM252 PF15664.5 EWM28446.1 - 0.033 13.9 1.4 0.89 9.3 0.2 2.3 2 0 0 2 2 2 0 Transmembrane protein 252 family MetOD1 PF18546.1 EWM28446.1 - 0.035 14.1 0.0 0.05 13.6 0.0 1.2 1 0 0 1 1 1 0 Metanogen output domain 1 FliG_C PF01706.16 EWM28447.1 - 0.15 12.2 0.1 0.29 11.4 0.1 1.4 1 0 0 1 1 1 0 FliG C-terminal domain DUF747 PF05346.11 EWM28448.1 - 9.4e-66 222.5 5.2 1.1e-65 222.2 5.2 1.0 1 0 0 1 1 1 1 Eukaryotic membrane protein family vMSA PF00695.19 EWM28448.1 - 0.087 11.9 1.3 0.16 11.0 1.3 1.3 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Atrophin-1 PF03154.15 EWM28448.1 - 3.6 5.8 6.2 4.7 5.4 6.2 1.1 1 0 0 1 1 1 0 Atrophin-1 family HemY_N PF07219.13 EWM28448.1 - 4.9 7.4 7.8 1.4 9.1 0.2 2.4 2 0 0 2 2 2 0 HemY protein N-terminus Asp_Arg_Hydrox PF05118.15 EWM28449.1 - 6.9e-41 139.7 0.4 8.3e-20 71.2 0.0 2.1 2 0 0 2 2 2 2 Aspartyl/Asparaginyl beta-hydroxylase OCIA PF07051.11 EWM28449.1 - 0.11 12.6 0.1 0.28 11.2 0.1 1.6 1 0 0 1 1 1 0 Ovarian carcinoma immunoreactive antigen (OCIA) Asp_Arg_Hydrox PF05118.15 EWM28450.1 - 3.9e-38 130.7 0.1 1.5e-18 67.1 0.1 2.1 2 0 0 2 2 2 2 Aspartyl/Asparaginyl beta-hydroxylase OCIA PF07051.11 EWM28450.1 - 0.11 12.5 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 Ovarian carcinoma immunoreactive antigen (OCIA) Mem_trans PF03547.18 EWM28452.1 - 0.22 9.9 0.5 0.28 9.5 0.5 1.2 1 0 0 1 1 1 0 Membrane transport protein NOA36 PF06524.12 EWM28452.1 - 0.23 10.8 16.1 0.43 9.9 16.1 1.3 1 0 0 1 1 1 0 NOA36 protein Ribosomal_S24e PF01282.19 EWM28456.1 - 5.2e-32 109.6 0.7 1.3e-31 108.3 0.0 1.9 1 1 1 2 2 2 1 Ribosomal protein S24e GTP_EFTU PF00009.27 EWM28457.1 - 1.4e-57 194.4 0.1 1.9e-57 194.0 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EWM28457.1 - 5.3e-05 23.3 0.0 0.0001 22.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 EWM28457.1 - 0.013 15.1 0.3 0.035 13.7 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 EWM28457.1 - 0.013 15.4 0.1 0.11 12.3 0.0 2.2 2 1 0 2 2 2 0 RsgA GTPase Ribosomal_S8 PF00410.19 EWM28457.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S8 Vps39_1 PF10366.9 EWM28457.1 - 0.16 12.3 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 GTP_EFTU_D3 PF03143.17 EWM28458.1 - 1.9e-28 99.0 0.0 2.6e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EWM28458.1 - 0.0054 17.1 0.0 0.027 14.8 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 DUF4129 PF13559.6 EWM28459.1 - 0.0018 18.5 1.1 0.91 9.8 0.0 3.6 2 1 1 3 3 3 2 Domain of unknown function (DUF4129) Acetyltransf_1 PF00583.25 EWM28460.1 - 7.4e-15 55.2 0.0 1.6e-14 54.1 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EWM28460.1 - 6.4e-09 35.8 0.0 1e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EWM28460.1 - 4.2e-07 30.3 0.0 7.7e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EWM28460.1 - 0.00063 19.7 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EWM28460.1 - 0.0026 17.8 0.0 0.0046 17.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EWM28460.1 - 0.0054 16.8 0.1 0.015 15.4 0.0 1.8 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Lentivirus_VIF PF05851.11 EWM28460.1 - 0.062 12.2 1.4 0.099 11.5 1.4 1.2 1 0 0 1 1 1 0 Lentivirus virion infectivity factor (VIF) dsDNA_bind PF01984.20 EWM28461.1 - 3.4e-28 98.1 7.0 4.1e-28 97.9 7.0 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Ribosomal_L9_C PF03948.14 EWM28461.1 - 0.057 13.9 0.4 0.091 13.2 0.4 1.4 1 0 0 1 1 1 0 Ribosomal protein L9, C-terminal domain HECT PF00632.25 EWM28462.1 - 4.2e-56 190.7 0.0 4.8e-56 190.5 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RMI1_C PF16099.5 EWM28464.1 - 0.072 12.9 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 Recq-mediated genome instability protein 1, C-terminal OB-fold TTL PF03133.15 EWM28465.1 - 1.1e-33 116.7 0.0 2.6e-33 115.4 0.0 1.5 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family LRR_6 PF13516.6 EWM28466.1 - 1.5e-20 71.4 7.2 0.0013 18.6 0.0 8.6 9 0 0 9 9 9 5 Leucine Rich repeat LRR_4 PF12799.7 EWM28466.1 - 6.4e-09 36.0 0.1 0.37 11.3 0.1 5.2 3 2 3 6 6 6 4 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EWM28466.1 - 0.00053 19.8 0.1 0.01 15.7 0.0 2.8 2 0 0 2 2 2 1 F-box-like LRR_1 PF00560.33 EWM28466.1 - 0.00075 19.7 12.6 25 5.9 0.1 7.7 7 2 0 7 7 7 1 Leucine Rich Repeat LRR_8 PF13855.6 EWM28466.1 - 0.0061 16.3 3.6 11 5.9 0.1 4.1 4 0 0 4 4 4 1 Leucine rich repeat FAD_binding_7 PF03441.14 EWM28467.1 - 2.7e-53 180.5 0.0 4.8e-53 179.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EWM28467.1 - 7.4e-29 100.9 0.0 1.2e-28 100.1 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase FAST_2 PF08368.12 EWM28467.1 - 0.11 13.3 0.0 0.21 12.4 0.0 1.4 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 2 AIRS_C PF02769.22 EWM28468.1 - 9.1e-08 32.4 0.1 1.2e-06 28.8 0.1 2.4 2 1 0 2 2 2 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 EWM28468.1 - 0.021 15.5 0.0 0.055 14.1 0.0 1.7 1 0 0 1 1 1 0 AIR synthase related protein, N-terminal domain DUF1345 PF07077.11 EWM28469.1 - 0.016 14.9 2.6 0.52 10.0 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) TMEM18 PF14770.6 EWM28469.1 - 6.1 6.9 8.1 3.7 7.6 1.6 2.8 2 1 1 3 3 3 0 Transmembrane protein 18 EMP24_GP25L PF01105.24 EWM28470.1 - 5.1e-31 108.0 0.0 6.3e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF1995 PF09353.10 EWM28471.1 - 5e-41 140.9 0.0 6.4e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) Ion_trans PF00520.31 EWM28472.1 - 2.5e-05 23.6 6.6 3.9e-05 23.0 6.6 1.2 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EWM28472.1 - 3.1e-05 22.9 2.6 4.8e-05 22.2 2.6 1.2 1 0 0 1 1 1 1 Polycystin cation channel COPI_assoc PF08507.10 EWM28473.1 - 4e-06 26.9 7.5 5.9e-06 26.4 7.5 1.2 1 0 0 1 1 1 1 COPI associated protein DUF1206 PF06724.11 EWM28473.1 - 0.0071 16.4 0.6 0.58 10.3 0.0 3.1 3 0 0 3 3 3 1 Domain of Unknown Function (DUF1206) PPR PF01535.20 EWM28474.1 - 6.4e-10 38.6 9.8 1.1 9.6 0.0 10.2 10 1 1 11 11 11 4 PPR repeat PPR_2 PF13041.6 EWM28474.1 - 1.1e-08 35.2 0.3 0.0022 18.1 0.0 5.5 5 0 0 5 5 5 2 PPR repeat family PPR_3 PF13812.6 EWM28474.1 - 5.1e-07 29.7 0.0 4.8e-05 23.4 0.0 3.4 2 1 1 3 3 3 1 Pentatricopeptide repeat domain MRP-S27 PF10037.9 EWM28474.1 - 0.00012 21.1 0.0 0.0003 19.8 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 PPR_long PF17177.4 EWM28474.1 - 0.0022 17.4 0.0 0.02 14.3 0.0 2.4 1 1 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EWM28474.1 - 0.0082 15.8 0.0 0.028 14.1 0.0 2.0 1 0 0 1 1 1 1 PPR repeat DUF1336 PF07059.12 EWM28475.1 - 2.7e-48 165.0 0.0 4.8e-48 164.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) Atg14 PF10186.9 EWM28475.1 - 0.0064 15.6 2.4 1.1 8.3 0.0 2.4 2 0 0 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 UvrA_inter PF17760.1 EWM28475.1 - 0.14 12.2 0.1 0.32 11.1 0.1 1.5 1 0 0 1 1 1 0 UvrA interaction domain BRE1 PF08647.11 EWM28475.1 - 0.69 10.0 9.4 3.8 7.6 0.3 2.6 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Apis_Csd PF11671.8 EWM28475.1 - 2.3 8.2 9.0 0.055 13.5 0.9 2.2 2 0 0 2 2 2 0 Complementary sex determiner protein Rad51 PF08423.11 EWM28476.1 - 6.3e-15 55.1 0.2 6.7e-15 55.0 0.2 1.1 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 EWM28476.1 - 4.4e-05 23.0 0.1 5e-05 22.7 0.1 1.1 1 0 0 1 1 1 1 KaiC RecA PF00154.21 EWM28476.1 - 0.00058 19.4 0.3 0.0007 19.1 0.3 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 EWM28476.1 - 0.00072 19.2 0.1 0.00089 18.9 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EWM28476.1 - 0.018 15.2 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.15 EWM28476.1 - 0.018 14.4 0.0 0.018 14.4 0.0 1.4 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Zot PF05707.12 EWM28476.1 - 0.048 13.3 0.0 3 7.4 0.0 2.1 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) PhoH PF02562.16 EWM28476.1 - 0.14 11.6 0.1 0.18 11.2 0.1 1.1 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EWM28476.1 - 0.16 12.4 0.2 0.24 11.9 0.2 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 EWM28476.1 - 0.19 11.0 0.1 0.23 10.7 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FTCD PF02971.14 EWM28477.1 - 0.25 11.4 0.3 0.33 11.0 0.3 1.1 1 0 0 1 1 1 0 Formiminotransferase domain Na_Ca_ex PF01699.24 EWM28478.1 - 8.1e-06 25.9 1.2 1e-05 25.5 1.2 1.1 1 0 0 1 1 1 1 Sodium/calcium exchanger protein COX8 PF02285.15 EWM28478.1 - 0.0094 15.8 0.5 0.0094 15.8 0.5 2.2 2 0 0 2 2 2 1 Cytochrome oxidase c subunit VIII WD40 PF00400.32 EWM28479.1 - 9.5e-12 45.3 0.6 0.00012 22.8 0.1 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM28479.1 - 2.5e-05 24.5 0.0 0.013 15.8 0.0 2.6 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain IBN_N PF03810.19 EWM28480.1 - 7.8e-07 28.9 0.0 2.9e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EWM28480.1 - 0.00024 21.2 0.0 0.0006 19.9 0.0 1.7 1 0 0 1 1 1 1 Exportin 1-like protein DUF4954 PF16314.5 EWM28481.1 - 1.4e-12 46.6 0.0 1.7e-09 36.4 0.0 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4954) CRAL_TRIO PF00650.20 EWM28482.1 - 6.1e-20 71.5 0.0 9e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain Proton_antipo_M PF00361.20 EWM28482.1 - 0.028 13.6 4.3 0.058 12.6 4.3 1.4 1 0 0 1 1 1 0 Proton-conducting membrane transporter DUF1460 PF07313.12 EWM28482.1 - 0.16 11.3 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) Epimerase PF01370.21 EWM28483.1 - 2.6e-20 72.9 0.0 7.9e-20 71.3 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EWM28483.1 - 2.8e-14 52.8 0.0 4.8e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EWM28483.1 - 3.9e-09 36.7 0.0 7.3e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EWM28483.1 - 6.8e-08 32.3 0.0 2.2e-07 30.6 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EWM28483.1 - 2e-07 30.5 0.1 2.3e-06 27.0 0.0 2.3 2 1 0 2 2 2 1 Male sterility protein NmrA PF05368.13 EWM28483.1 - 1.3e-05 24.9 0.0 2.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 EWM28483.1 - 0.15 11.2 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.25 EWM28483.1 - 0.23 10.9 0.0 0.38 10.2 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase AA_permease_2 PF13520.6 EWM28484.1 - 4.8e-39 134.4 35.8 1.2e-37 129.8 35.8 2.1 1 1 0 1 1 1 1 Amino acid permease His_Phos_1 PF00300.22 EWM28486.1 - 1.8e-36 125.7 0.1 2.4e-36 125.3 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF72 PF01904.18 EWM28487.1 - 2.8e-51 174.7 0.1 3.9e-51 174.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF72 SNF2_N PF00176.23 EWM28488.1 - 1e-59 202.1 0.0 1.7e-59 201.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EWM28488.1 - 1.6e-19 70.3 0.0 4.2e-19 68.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EWM28488.1 - 0.001 19.1 0.0 0.0028 17.7 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit MAGE PF01454.19 EWM28489.1 - 6.2e-17 62.0 0.0 2.8e-16 59.9 0.0 2.0 1 1 0 1 1 1 1 MAGE family AAA_23 PF13476.6 EWM28490.1 - 8.6e-24 85.2 33.8 8.6e-24 85.2 33.8 7.5 1 1 3 4 4 2 1 AAA domain AAA_21 PF13304.6 EWM28490.1 - 8.4e-10 38.9 1.1 0.00011 22.2 0.0 3.4 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EWM28490.1 - 4.3e-06 26.7 25.1 1.8e-05 24.6 0.0 4.8 2 2 1 3 3 3 1 AAA ATPase domain SMC_N PF02463.19 EWM28490.1 - 1.4e-05 24.6 39.3 0.00019 20.9 39.3 2.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EWM28490.1 - 0.00025 21.2 0.0 0.00084 19.5 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EWM28490.1 - 0.00064 19.4 0.0 0.0018 18.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF4618 PF15397.6 EWM28490.1 - 0.006 16.0 2.5 0.006 16.0 2.5 9.3 5 4 1 7 7 6 1 Domain of unknown function (DUF4618) ABC_tran PF00005.27 EWM28490.1 - 0.016 15.7 0.0 0.016 15.7 0.0 6.3 5 3 0 5 5 5 0 ABC transporter DUF5615 PF18480.1 EWM28490.1 - 0.1 12.4 0.0 0.32 10.8 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) NSP2-B_epitope PF14757.6 EWM28490.1 - 0.11 12.2 5.6 1.2 8.7 0.1 3.0 3 0 0 3 3 3 0 Immunogenic region of nsp2 protein of arterivirus polyprotein TBD PF12845.7 EWM28490.1 - 0.13 12.1 3.3 1.5 8.8 0.2 3.6 2 0 0 2 2 2 0 TBD domain AAA_16 PF13191.6 EWM28490.1 - 0.37 11.2 0.0 0.37 11.2 0.0 5.1 4 2 0 4 4 3 0 AAA ATPase domain MMR_HSR1 PF01926.23 EWM28491.1 - 5.9e-19 68.2 0.1 1.3e-18 67.1 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EWM28491.1 - 1e-09 38.1 0.0 1.5e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EWM28491.1 - 7.7e-06 25.9 0.0 0.00075 19.4 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EWM28491.1 - 5.4e-05 23.3 2.5 0.033 14.3 0.3 3.1 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 EWM28491.1 - 0.0016 18.0 0.8 0.026 14.1 0.0 2.6 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain IIGP PF05049.13 EWM28491.1 - 0.019 14.0 0.8 0.025 13.6 0.0 1.5 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) SRPRB PF09439.10 EWM28491.1 - 0.035 13.5 0.2 0.081 12.4 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 EWM28491.1 - 0.12 12.9 0.2 0.36 11.3 0.0 1.8 2 0 0 2 2 2 0 ABC transporter OmpH PF03938.14 EWM28491.1 - 0.59 10.5 10.3 1 9.7 10.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) EMC3_TMCO1 PF01956.16 EWM28491.1 - 4.3 7.0 4.9 11 5.7 4.9 1.8 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like PP2C PF00481.21 EWM28492.1 - 5.1e-28 98.4 0.1 3.8e-21 75.9 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EWM28492.1 - 3.7e-08 33.3 0.4 2.4e-07 30.6 0.4 2.3 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EWM28492.1 - 0.00019 21.4 0.4 0.00086 19.3 0.1 2.0 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) RPA_C PF08784.11 EWM28494.1 - 1.4e-11 45.0 0.8 3e-11 43.9 0.5 1.7 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 EWM28494.1 - 1.1e-06 28.6 0.6 1.9e-06 27.8 0.6 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 EWM28494.1 - 0.00041 20.2 0.1 0.00064 19.5 0.1 1.3 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 TBPIP PF07106.13 EWM28494.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain Keratin_2_head PF16208.5 EWM28494.1 - 0.41 10.8 28.4 0.041 14.0 5.6 2.3 2 0 0 2 2 2 0 Keratin type II head SET PF00856.28 EWM28495.1 - 1.9e-05 25.1 0.0 2.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 SET domain Cep57_CLD_2 PF14197.6 EWM28497.1 - 0.21 11.7 0.0 0.35 11.0 0.0 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 GTP_EFTU PF00009.27 EWM28498.1 - 1.1e-23 83.8 0.0 1.8e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EWM28498.1 - 3.8e-05 23.9 0.0 0.00011 22.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 EWM28498.1 - 0.001 19.2 0.2 0.0026 17.8 0.2 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 EWM28498.1 - 0.0033 17.8 0.1 0.012 16.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 PduV-EutP PF10662.9 EWM28498.1 - 0.011 15.5 0.0 4.6 7.0 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF3789 PF12664.7 EWM28498.1 - 0.047 13.4 0.6 0.047 13.4 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3789) RNA_pol_3_Rpc31 PF11705.8 EWM28499.1 - 0.01 16.1 15.6 0.014 15.6 15.6 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Exo_endo_phos PF03372.23 EWM28499.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.5 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DEAD PF00270.29 EWM28500.1 - 6.1e-44 149.9 0.1 1.2e-43 148.9 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EWM28500.1 - 5.2e-30 104.0 0.1 4.2e-29 101.1 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EWM28500.1 - 0.00018 21.6 0.0 0.00086 19.3 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit VPS13_C PF16909.5 EWM28501.1 - 1.7e-45 155.0 2.2 7.7e-42 143.1 0.1 2.4 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 EWM28501.1 - 1e-19 71.0 0.0 4e-18 65.8 0.0 3.2 4 0 0 4 4 4 1 SHR-binding domain of vacuolar-sorting associated protein 13 ATG_C PF09333.11 EWM28501.1 - 2.7e-08 34.0 0.0 7e-07 29.5 0.0 2.9 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Pex24p PF06398.11 EWM28501.1 - 3e-08 33.1 9.0 4.5e-08 32.5 9.0 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Yae1_N PF09811.9 EWM28502.1 - 1.4e-06 27.9 7.8 2.6e-06 27.0 7.8 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal RRM_1 PF00076.22 EWM28503.1 - 2.2e-30 104.3 0.7 1.4e-16 60.0 0.1 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EWM28503.1 - 0.00097 19.1 0.1 0.28 11.2 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EWM28503.1 - 0.0026 17.8 0.1 0.31 11.2 0.1 2.6 2 1 0 2 2 2 1 RNA recognition motif PHM7_cyt PF14703.6 EWM28503.1 - 8.6 6.6 7.1 57 3.9 0.0 3.9 3 2 2 5 5 5 0 Cytosolic domain of 10TM putative phosphate transporter DS PF01916.17 EWM28504.1 - 1.3e-127 425.0 0.0 1.5e-127 424.8 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase DUF4660 PF15559.6 EWM28505.1 - 0.14 12.5 7.0 0.22 11.9 1.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4660) ABC_tran_Xtn PF12848.7 EWM28506.1 - 1.3 9.1 11.4 0.031 14.3 2.6 2.4 2 0 0 2 2 2 0 ABC transporter Sulfotransfer_3 PF13469.6 EWM28507.1 - 2e-31 110.0 0.0 4e-31 109.1 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 EWM28507.1 - 9.2e-07 28.6 0.1 1.7e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_4 PF17784.1 EWM28507.1 - 0.0055 16.6 1.0 0.008 16.0 0.0 1.9 3 0 0 3 3 3 1 Sulfotransferase domain Cytochrom_B558a PF05038.13 EWM28507.1 - 0.41 10.2 1.8 1.2 8.7 0.4 2.0 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit DUF3591 PF12157.8 EWM28508.1 - 3.6e-55 187.4 0.0 1.5e-54 185.3 0.0 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF3591) DUF2020 PF09449.10 EWM28508.1 - 1 9.2 2.6 2.8 7.8 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2020) RNase_T PF00929.24 EWM28509.1 - 1e-14 55.4 0.0 1.8e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 EWM28509.1 - 0.00061 19.5 0.0 0.0024 17.6 0.0 1.8 1 1 0 1 1 1 1 3'-5' exonuclease UPF0240 PF06784.11 EWM28509.1 - 0.048 13.7 0.3 0.1 12.6 0.3 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) Lipocalin_2 PF08212.12 EWM28512.1 - 3.7e-13 49.6 0.0 5.5e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Lipocalin-like domain TGT PF01702.18 EWM28513.1 - 2e-104 349.5 0.0 1e-103 347.2 0.0 1.9 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase Isochorismatase PF00857.20 EWM28514.1 - 5.3e-24 85.3 0.3 7.6e-24 84.8 0.3 1.2 1 0 0 1 1 1 1 Isochorismatase family TPMT PF05724.11 EWM28515.1 - 4.2e-32 111.6 0.0 5.3e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 EWM28515.1 - 6.2e-08 33.2 0.0 9.8e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM28515.1 - 5.8e-07 29.4 0.0 7.8e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM28515.1 - 5.4e-05 23.8 0.0 8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EWM28515.1 - 0.0012 19.5 0.0 0.002 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain HPP PF04982.13 EWM28516.1 - 8.3e-40 135.8 6.8 1.3e-39 135.1 6.8 1.3 1 0 0 1 1 1 1 HPP family SBDS_C PF09377.10 EWM28517.1 - 4e-30 104.2 0.0 6.9e-30 103.4 0.0 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 EWM28517.1 - 1.9e-27 95.1 0.0 5.2e-27 93.8 0.0 1.8 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein zf-C2H2_jaz PF12171.8 EWM28517.1 - 0.0059 16.9 0.1 0.011 16.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EWM28517.1 - 0.078 13.4 0.2 0.49 10.9 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type PGA2 PF07543.12 EWM28517.1 - 9.1 6.3 18.0 20 5.1 18.0 1.7 1 0 0 1 1 1 0 Protein trafficking PGA2 GDPD PF03009.17 EWM28518.1 - 3.7e-45 154.7 0.0 1.1e-44 153.2 0.0 1.7 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Pyr_redox_2 PF07992.14 EWM28519.1 - 1.8e-21 76.7 0.0 2.7e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AIF_C PF14721.6 EWM28519.1 - 2e-15 57.3 0.0 7.6e-08 32.8 0.0 2.4 1 1 1 2 2 2 2 Apoptosis-inducing factor, mitochondrion-associated, C-term Pyr_redox PF00070.27 EWM28519.1 - 3.2e-06 27.6 0.4 7.7e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EWM28519.1 - 0.095 11.8 0.0 9.9 5.2 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) HECT PF00632.25 EWM28520.1 - 3.2e-85 286.3 0.0 4.6e-85 285.8 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1 PF00415.18 EWM28520.1 - 7.5e-46 154.5 30.0 7.1e-10 39.4 0.6 8.5 7 2 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EWM28520.1 - 6.2e-44 147.0 39.0 4e-08 32.8 1.9 7.3 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Dynamitin PF04912.14 EWM28520.1 - 0.014 14.7 0.2 0.023 14.0 0.2 1.2 1 0 0 1 1 1 0 Dynamitin ATP_bind_1 PF03029.17 EWM28521.1 - 5e-78 262.2 0.1 6.1e-78 261.9 0.1 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 EWM28521.1 - 2.8e-05 23.7 0.0 0.00029 20.4 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 EWM28521.1 - 0.00016 21.0 0.0 0.25 10.5 0.0 2.6 2 1 1 3 3 3 2 G-protein alpha subunit cobW PF02492.19 EWM28521.1 - 0.00019 21.1 0.0 0.25 10.9 0.0 2.2 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 EWM28521.1 - 0.00049 20.2 0.0 0.0028 17.7 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EWM28521.1 - 0.0007 20.0 0.0 0.0044 17.4 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain SRP54 PF00448.22 EWM28521.1 - 0.0009 18.9 0.0 0.0062 16.2 0.0 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain MeaB PF03308.16 EWM28521.1 - 0.00099 18.2 0.0 0.0064 15.5 0.0 1.9 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 EWM28521.1 - 0.0013 18.5 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Torsin PF06309.11 EWM28521.1 - 0.0013 18.8 0.0 0.0024 18.0 0.0 1.3 1 0 0 1 1 1 1 Torsin APS_kinase PF01583.20 EWM28521.1 - 0.0017 18.3 0.1 0.0041 17.0 0.0 1.7 2 0 0 2 2 1 1 Adenylylsulphate kinase RsgA_GTPase PF03193.16 EWM28521.1 - 0.002 18.0 0.0 0.64 9.9 0.0 2.8 3 0 0 3 3 3 1 RsgA GTPase PduV-EutP PF10662.9 EWM28521.1 - 0.0022 17.8 0.0 0.014 15.1 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 EWM28521.1 - 0.0025 17.7 0.0 0.0049 16.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain FeoB_N PF02421.18 EWM28521.1 - 0.0028 17.2 0.1 0.018 14.5 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_33 PF13671.6 EWM28521.1 - 0.0031 17.7 0.1 0.0061 16.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 EWM28521.1 - 0.0033 16.9 0.0 0.29 10.5 0.0 2.2 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MobB PF03205.14 EWM28521.1 - 0.007 16.3 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 EWM28521.1 - 0.0074 16.6 0.0 0.019 15.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain NB-ARC PF00931.22 EWM28521.1 - 0.0084 15.3 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_7 PF12775.7 EWM28521.1 - 0.0096 15.5 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region NTPase_1 PF03266.15 EWM28521.1 - 0.011 15.7 0.0 0.036 14.0 0.0 1.8 1 1 0 1 1 1 0 NTPase Zeta_toxin PF06414.12 EWM28521.1 - 0.021 14.1 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Arf PF00025.21 EWM28521.1 - 0.022 14.2 0.1 0.1 12.0 0.1 2.0 2 1 0 2 2 2 0 ADP-ribosylation factor family AAA_31 PF13614.6 EWM28521.1 - 0.03 14.2 0.0 0.45 10.4 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EWM28521.1 - 0.03 14.9 0.0 0.059 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain CLP1_P PF16575.5 EWM28521.1 - 0.035 13.9 0.0 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Rad17 PF03215.15 EWM28521.1 - 0.036 14.0 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Gtr1_RagA PF04670.12 EWM28521.1 - 0.04 13.3 0.0 1.8 7.9 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_28 PF13521.6 EWM28521.1 - 0.1 12.8 0.4 4.6 7.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 EWM28521.1 - 0.19 11.1 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Viral_helicase1 PF01443.18 EWM28521.1 - 0.2 11.4 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase eRF1_1 PF03463.15 EWM28523.1 - 0.14 12.2 0.1 0.27 11.2 0.1 1.4 1 0 0 1 1 1 0 eRF1 domain 1 Mito_fiss_reg PF05308.11 EWM28523.1 - 0.62 10.1 4.9 1.4 9.0 4.9 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF3645 PF12359.8 EWM28524.1 - 0.2 11.1 0.4 0.4 10.1 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3645) MMS19_N PF14500.6 EWM28526.1 - 2.4e-69 233.8 0.0 6.6e-68 229.1 0.0 2.5 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 EWM28526.1 - 2.8e-32 112.4 0.0 3.9e-30 105.3 0.0 3.5 3 2 0 3 3 3 1 RNAPII transcription regulator C-terminal Pas_Saposin PF09016.10 EWM28526.1 - 0.33 11.3 1.0 3.3 8.1 0.0 2.8 3 0 0 3 3 3 0 Pas factor saposin fold Med26 PF08711.11 EWM28527.1 - 1.1e-10 41.3 0.6 5.1e-10 39.2 0.5 2.2 2 0 0 2 2 2 1 TFIIS helical bundle-like domain CRAL_TRIO PF00650.20 EWM28528.1 - 3.4e-29 101.6 0.0 4.8e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EWM28528.1 - 0.0009 19.4 0.0 0.0018 18.5 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain PH PF00169.29 EWM28528.1 - 0.0034 17.9 0.0 0.0075 16.8 0.0 1.5 1 0 0 1 1 1 1 PH domain RRM_1 PF00076.22 EWM28529.1 - 2.4e-37 126.6 0.0 3.2e-17 62.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAP PF02037.27 EWM28529.1 - 6.4e-11 41.7 0.3 1.2e-10 40.8 0.3 1.5 1 0 0 1 1 1 1 SAP domain RRM_7 PF16367.5 EWM28529.1 - 1.9e-06 27.9 0.0 0.00025 21.1 0.0 3.4 3 0 0 3 3 3 1 RNA recognition motif Nup35_RRM_2 PF14605.6 EWM28529.1 - 2.7e-06 27.3 0.0 0.068 13.2 0.0 2.7 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 EWM28529.1 - 0.074 13.1 0.2 2.9 8.0 0.0 3.1 3 0 0 3 3 3 0 Limkain b1 Efg1 PF10153.9 EWM28529.1 - 0.97 9.8 3.9 5 7.5 0.0 2.7 2 0 0 2 2 2 0 rRNA-processing protein Efg1 DUF2052 PF09747.9 EWM28529.1 - 3.4 7.7 12.9 7.7 6.6 12.9 1.6 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Ion_trans PF00520.31 EWM28530.1 - 5.1e-40 137.2 36.7 2e-22 79.6 20.2 2.1 2 0 0 2 2 2 2 Ion transport protein Acetyltransf_1 PF00583.25 EWM28531.1 - 3.8e-14 52.9 0.0 5.8e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EWM28531.1 - 1.5e-10 41.1 0.0 3e-10 40.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EWM28531.1 - 3.3e-08 33.8 0.0 5.2e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EWM28531.1 - 5.4e-08 32.7 0.0 9.8e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein PanZ PF12568.8 EWM28531.1 - 0.0029 17.3 0.0 0.0053 16.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 EWM28531.1 - 0.028 14.5 0.1 0.09 12.9 0.0 1.8 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Sporozoite_P67 PF05642.11 EWM28531.1 - 1.5 6.8 4.6 2 6.4 4.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FbpC_C_terminal PF17845.1 EWM28532.1 - 0.053 13.6 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 FbpC C-terminal regulatory nucleotide binding domain YjbT PF17089.5 EWM28532.1 - 0.081 12.9 0.9 0.97 9.5 0.1 2.8 3 0 0 3 3 3 0 Uncharacterised protein family Tubulin PF00091.25 EWM28533.1 - 3.8e-69 232.8 0.0 6.7e-69 232.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EWM28533.1 - 1.2e-40 138.5 0.1 1.9e-40 137.9 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EWM28533.1 - 0.0001 22.6 0.0 0.00025 21.4 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EWM28533.1 - 0.003 17.3 0.0 0.0059 16.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EWM28533.1 - 0.02 14.1 0.0 0.039 13.2 0.0 1.4 1 0 0 1 1 1 0 Tubulin like EXOSC1 PF10447.9 EWM28534.1 - 3.6e-12 46.8 2.9 1.8e-07 31.7 0.3 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 EWM28534.1 - 9.2e-11 41.4 0.2 2.1e-10 40.2 0.2 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.23 EWM28534.1 - 0.13 12.6 0.5 0.96 9.8 0.5 2.3 1 1 0 1 1 1 0 S1 RNA binding domain LRR_6 PF13516.6 EWM28535.1 - 3.1e-06 26.8 21.9 0.35 11.1 0.1 6.3 6 0 0 6 6 6 4 Leucine Rich repeat LRR_4 PF12799.7 EWM28535.1 - 0.00023 21.5 18.9 0.33 11.4 1.5 5.0 3 2 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EWM28535.1 - 0.0025 18.1 18.0 2 9.3 0.1 6.9 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_8 PF13855.6 EWM28535.1 - 9 6.2 21.6 5.2 6.9 1.0 5.5 4 1 1 5 5 5 0 Leucine rich repeat SNO PF01174.19 EWM28536.1 - 3.8e-44 150.8 0.0 5.5e-36 124.2 0.0 2.1 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 EWM28536.1 - 4.1e-09 36.3 0.1 7.3e-09 35.5 0.1 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 EWM28536.1 - 8.9e-05 22.4 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_S51 PF03575.17 EWM28536.1 - 0.00016 21.4 0.0 0.00025 20.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 GATase PF00117.28 EWM28536.1 - 0.002 17.9 1.1 0.062 13.1 1.1 2.2 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EWM28536.1 - 0.035 13.8 1.7 2.3 7.9 0.3 3.0 2 1 0 2 2 2 0 Peptidase C26 TFIIA PF03153.13 EWM28537.1 - 7.4 6.4 6.6 0.76 9.7 0.5 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit HTH_11 PF08279.12 EWM28539.1 - 0.063 13.2 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 HTH domain Pertussis_S1 PF02917.14 EWM28539.1 - 0.092 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Pertussis toxin, subunit 1 N6_N4_Mtase PF01555.18 EWM28539.1 - 0.12 12.1 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 DNA methylase Guanylate_kin PF00625.21 EWM28540.1 - 1.9e-58 197.2 0.0 2.6e-58 196.7 0.0 1.2 1 0 0 1 1 1 1 Guanylate kinase RIIa PF02197.17 EWM28540.1 - 3.2e-05 23.5 0.9 8e-05 22.2 0.9 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit AAA_33 PF13671.6 EWM28540.1 - 0.00013 22.1 0.0 0.0012 19.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EWM28540.1 - 0.00061 20.3 0.0 0.0014 19.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EWM28540.1 - 0.0011 18.9 0.0 0.003 17.5 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EWM28540.1 - 0.0077 16.5 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EWM28540.1 - 0.023 15.1 0.0 0.044 14.2 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 EWM28540.1 - 0.023 14.8 0.0 0.045 13.8 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Septin PF00735.18 EWM28540.1 - 0.047 13.0 0.0 0.073 12.3 0.0 1.3 1 0 0 1 1 1 0 Septin T3SS_needle_E PF08988.10 EWM28540.1 - 0.052 13.7 0.1 0.21 11.8 0.0 2.0 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle RNA_helicase PF00910.22 EWM28540.1 - 0.057 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 EWM28540.1 - 0.1 13.1 0.0 0.25 11.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Rad17 PF03215.15 EWM28540.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain FKBP_C PF00254.28 EWM28541.1 - 1.8e-11 44.2 0.1 3.3e-11 43.3 0.1 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PIN_8 PF18476.1 EWM28543.1 - 1.2 9.0 4.5 2.6 7.8 4.5 1.5 1 0 0 1 1 1 0 PIN like domain TolA_bind_tri PF16331.5 EWM28543.1 - 1.8 8.7 10.4 5.6 7.1 8.5 2.4 2 0 0 2 2 2 0 TolA binding protein trimerisation Peptidase_M1 PF01433.20 EWM28544.1 - 1.2e-44 152.5 0.1 3e-44 151.2 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 EWM28544.1 - 3.3e-37 127.0 0.1 7.1e-37 126.0 0.1 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 EWM28544.1 - 3e-16 60.1 0.0 4.9e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Nup54 PF13874.6 EWM28545.1 - 9e-10 38.8 6.0 9e-10 38.8 6.0 2.9 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 DUF4105 PF13387.6 EWM28545.1 - 0.00095 18.8 0.0 1.7 8.2 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4105) TFIIA PF03153.13 EWM28545.1 - 0.042 13.9 26.0 0.21 11.6 10.4 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit FUSC PF04632.12 EWM28545.1 - 0.33 9.4 15.4 0.0047 15.5 7.8 1.7 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF1612 PF07756.12 EWM28545.1 - 0.42 10.9 5.4 0.4 11.0 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1612) Spt20 PF12090.8 EWM28545.1 - 3.6 7.1 27.0 0.03 14.0 10.5 2.4 2 0 0 2 2 2 0 Spt20 family DUF533 PF04391.12 EWM28545.1 - 4.1 6.9 13.5 4.5 6.8 1.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF533) Sporozoite_P67 PF05642.11 EWM28545.1 - 5.8 4.9 19.9 11 4.0 19.5 1.5 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Ribosomal_L10 PF00466.20 EWM28546.1 - 1.6e-20 73.1 0.0 3.6e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 EWM28546.1 - 2.1e-20 72.5 0.2 6e-20 71.0 0.2 1.8 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 EWM28546.1 - 3.1e-09 37.3 7.2 5.5e-09 36.5 7.2 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein Beta_elim_lyase PF01212.21 EWM28547.1 - 1.3e-86 290.5 0.1 1.7e-86 290.1 0.1 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EWM28547.1 - 1.1e-08 34.7 0.0 1.6e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EWM28547.1 - 2.8e-05 23.3 0.0 0.00036 19.6 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EWM28547.1 - 0.00033 20.1 0.1 0.015 14.6 0.1 2.6 3 0 0 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EWM28547.1 - 0.0017 16.9 0.0 0.0028 16.2 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SNF2_N PF00176.23 EWM28548.1 - 1.3e-11 43.9 0.0 1.7e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain PseudoU_synth_1 PF01416.20 EWM28549.1 - 6.7e-12 45.8 0.0 2.6e-08 34.3 0.0 3.2 3 0 0 3 3 3 2 tRNA pseudouridine synthase tRNA_NucTran2_2 PF13735.6 EWM28549.1 - 0.073 13.1 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative Dor1 PF04124.12 EWM28550.1 - 8e-48 162.8 2.6 5.7e-23 81.1 0.2 3.6 4 1 0 4 4 4 3 Dor1-like family Diphthamide_syn PF01866.17 EWM28552.1 - 6.8e-80 268.7 0.0 8.5e-80 268.4 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein SNF2_N PF00176.23 EWM28553.1 - 6.6e-62 209.3 0.1 6.6e-62 209.3 0.1 3.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EWM28553.1 - 1.9e-17 63.6 0.0 1.9e-17 63.6 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Linker_histone PF00538.19 EWM28553.1 - 5.3e-09 36.3 0.2 1.5e-08 34.9 0.2 1.9 1 0 0 1 1 1 1 linker histone H1 and H5 family C1_1 PF00130.22 EWM28553.1 - 0.0034 17.2 2.4 0.0034 17.2 2.4 2.5 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 EWM28553.1 - 0.0047 16.8 9.2 0.041 13.8 0.5 2.9 2 0 0 2 2 2 2 PHD-finger Zf_RING PF16744.5 EWM28553.1 - 1.8 8.8 9.4 0.47 10.6 0.2 3.0 2 0 0 2 2 2 0 KIAA1045 RING finger PLA2G12 PF06951.11 EWM28555.1 - 8.7e-13 48.6 15.0 5.2e-12 46.0 15.0 1.9 1 1 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) Img2 PF05046.14 EWM28556.1 - 1e-17 64.2 0.0 1.4e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Sec1 PF00995.23 EWM28557.1 - 2.5e-94 317.6 0.0 2.9e-94 317.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Sec1 PF00995.23 EWM28558.1 - 2.5e-94 317.6 0.0 2.9e-94 317.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family HNH_5 PF14279.6 EWM28559.1 - 1.2e-16 60.3 1.0 2.5e-16 59.3 1.0 1.5 1 0 0 1 1 1 1 HNH endonuclease HNH PF01844.23 EWM28559.1 - 6.9e-12 45.4 1.3 6.9e-12 45.4 1.3 1.9 2 0 0 2 2 2 1 HNH endonuclease HNH_4 PF13395.6 EWM28559.1 - 1.9e-11 43.7 0.0 3.3e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 HNH endonuclease Endonuclease_7 PF02945.15 EWM28559.1 - 0.029 14.3 1.3 0.061 13.2 1.3 1.5 1 0 0 1 1 1 0 Recombination endonuclease VII Glyco_hydro_8 PF01270.17 EWM28560.1 - 3.1e-30 105.2 3.4 4.7e-30 104.6 3.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 8 WD40 PF00400.32 EWM28561.1 - 5.7e-05 23.8 0.8 0.19 12.6 0.0 5.0 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM28561.1 - 0.005 17.1 0.0 0.25 11.6 0.0 3.1 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EWM28561.1 - 0.03 13.3 0.1 0.29 10.0 0.0 2.2 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TYW3 PF02676.14 EWM28561.1 - 0.26 10.6 0.9 0.43 9.9 0.9 1.3 1 0 0 1 1 1 0 Methyltransferase TYW3 Bmt2 PF11968.8 EWM28564.1 - 2.8e-38 132.0 0.0 3.7e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 EWM28564.1 - 0.00071 19.4 0.0 0.0014 18.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain CCDC158 PF15921.5 EWM28564.1 - 0.096 10.5 0.1 0.1 10.4 0.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 158 RRM_1 PF00076.22 EWM28565.1 - 1.5e-09 37.5 0.0 2.6e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 EWM28565.1 - 3.3e-07 31.0 0.1 5.8e-07 30.2 0.1 1.4 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 EWM28565.1 - 1.1e-06 28.5 1.9 2.1e-06 27.6 1.9 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 EWM28565.1 - 5.9e-06 26.1 1.8 5.9e-06 26.1 1.8 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EWM28565.1 - 9.1e-06 25.4 3.8 1.7e-05 24.5 3.8 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 EWM28565.1 - 0.015 15.5 0.1 0.031 14.5 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger containing family FYVE PF01363.21 EWM28565.1 - 0.02 15.0 1.6 0.023 14.8 0.4 1.8 2 0 0 2 2 2 0 FYVE zinc finger zf-CCCH_2 PF14608.6 EWM28565.1 - 0.095 13.2 2.3 0.2 12.2 2.3 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger GFO_IDH_MocA PF01408.22 EWM28567.1 - 7.7e-13 49.3 0.4 7e-12 46.2 0.4 2.1 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ECH_1 PF00378.20 EWM28568.1 - 3.5e-40 137.9 0.1 1.1e-38 132.9 0.1 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EWM28568.1 - 1.4e-25 90.5 0.1 1e-24 87.6 0.0 1.9 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Thioredoxin PF00085.20 EWM28569.1 - 0.00025 21.0 0.0 0.0081 16.1 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin FTR1 PF03239.14 EWM28570.1 - 0.068 12.3 3.4 0.097 11.8 3.4 1.2 1 0 0 1 1 1 0 Iron permease FTR1 family RPN7 PF10602.9 EWM28571.1 - 4.4e-42 143.7 5.4 6.4e-42 143.2 5.4 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EWM28571.1 - 8.1e-17 61.6 0.0 2.8e-16 59.9 0.0 2.0 2 0 0 2 2 2 1 PCI domain HSCB_C PF07743.13 EWM28571.1 - 1.8 9.1 5.1 0.41 11.2 0.2 2.4 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain eIF2A PF08662.11 EWM28572.1 - 1.9e-62 210.6 0.0 1.6e-61 207.6 0.0 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PQQ PF01011.21 EWM28572.1 - 0.029 14.3 0.0 0.08 12.9 0.0 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat WD40 PF00400.32 EWM28572.1 - 0.088 13.7 0.1 72 4.5 0.0 3.9 3 0 0 3 3 3 0 WD domain, G-beta repeat DUF3689 PF12463.8 EWM28574.1 - 2.3e-49 168.4 0.0 3.1e-35 122.0 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF3689) 60KD_IMP PF02096.20 EWM28575.1 - 1.2e-48 165.1 0.0 2e-48 164.4 0.0 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein B56 PF01603.20 EWM28576.1 - 1.6e-53 182.2 0.0 2.5e-53 181.6 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Pkinase PF00069.25 EWM28576.1 - 7.3e-31 107.5 0.0 1.1e-30 107.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM28576.1 - 5.8e-18 65.1 0.0 8.7e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AIG1 PF04548.16 EWM28576.1 - 0.057 12.7 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 AIG1 family RIO1 PF01163.22 EWM28576.1 - 0.078 12.6 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family TPR_12 PF13424.6 EWM28576.1 - 0.084 13.2 0.1 0.18 12.1 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Herpes_US9 PF06072.11 EWM28577.1 - 0.074 12.9 0.3 0.16 11.9 0.3 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 RRM_1 PF00076.22 EWM28578.1 - 1.3e-34 117.8 0.0 8.3e-18 64.0 0.0 4.0 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EWM28578.1 - 7e-08 32.5 0.0 0.0052 16.9 0.0 3.5 4 0 0 4 4 4 2 RNA recognition motif RRM_5 PF13893.6 EWM28578.1 - 0.024 14.3 0.0 0.19 11.4 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EWM28578.1 - 0.055 13.6 0.2 0.95 9.6 0.1 2.7 3 0 0 3 3 3 0 Limkain b1 PHM7_cyt PF14703.6 EWM28578.1 - 2.1 8.5 10.5 7.1 6.8 0.1 3.8 3 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter GrpE PF01025.19 EWM28579.1 - 4.3e-21 75.3 14.1 4.3e-21 75.3 14.1 2.0 2 1 0 2 2 2 1 GrpE Atg14 PF10186.9 EWM28579.1 - 0.014 14.5 4.4 0.018 14.1 3.6 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADH_N_2 PF16884.5 EWM28579.1 - 0.082 12.8 0.4 0.21 11.5 0.3 1.7 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase HIP1_clath_bdg PF16515.5 EWM28579.1 - 0.92 10.2 23.9 0.44 11.2 9.6 3.1 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 AAA_13 PF13166.6 EWM28579.1 - 0.93 8.0 10.2 0.015 14.0 3.4 1.7 2 0 0 2 2 2 0 AAA domain DUF4140 PF13600.6 EWM28579.1 - 0.96 9.9 14.9 0.19 12.2 6.2 2.8 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) GrpE PF01025.19 EWM28580.1 - 8.9e-09 35.2 12.0 1.9e-08 34.1 11.5 1.8 1 1 0 1 1 1 1 GrpE HIP1_clath_bdg PF16515.5 EWM28580.1 - 0.0071 16.9 15.7 0.38 11.4 9.6 2.3 1 1 1 2 2 2 2 Clathrin-binding domain of Huntingtin-interacting protein 1 AAA_13 PF13166.6 EWM28580.1 - 0.013 14.2 3.8 0.017 13.8 3.8 1.4 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.9 EWM28580.1 - 0.014 14.5 4.4 0.015 14.4 3.8 1.3 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4140 PF13600.6 EWM28580.1 - 0.81 10.2 10.1 0.21 12.1 6.5 1.9 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DNA_pol_phi PF04931.13 EWM28580.1 - 1.4 7.0 11.2 1.8 6.6 11.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Phlebovirus_NSM PF07246.11 EWM28580.1 - 1.4 8.2 4.7 2.2 7.6 4.7 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Exonuc_VII_L PF02601.15 EWM28580.1 - 2.6 7.6 6.5 3.8 7.0 6.3 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit OmpH PF03938.14 EWM28580.1 - 5.6 7.3 17.5 0.11 12.9 9.1 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) HBS1_N PF08938.10 EWM28580.1 - 5.7 7.3 10.5 17 5.8 10.5 1.8 1 1 0 1 1 1 0 HBS1 N-terminus YabA PF06156.13 EWM28580.1 - 5.8 7.6 7.4 2.6 8.7 4.1 2.0 1 1 1 2 2 2 0 Initiation control protein YabA DUF4407 PF14362.6 EWM28580.1 - 8.5 5.6 12.5 2.5 7.4 9.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) MgtE PF01769.16 EWM28581.1 - 9.5e-11 42.2 4.1 9.5e-11 42.2 4.1 2.6 3 1 1 4 4 4 1 Divalent cation transporter CBS PF00571.28 EWM28581.1 - 5.3e-09 36.4 1.7 1.5e-05 25.3 0.3 2.7 2 0 0 2 2 2 2 CBS domain Pkinase PF00069.25 EWM28582.1 - 4.2e-70 236.1 0.0 6.1e-70 235.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM28582.1 - 3.4e-38 131.4 0.0 5.3e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Arb2 PF09757.9 EWM28582.1 - 3.7e-05 23.0 0.0 6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Arb2 domain Haspin_kinase PF12330.8 EWM28582.1 - 0.00092 18.3 0.1 0.0017 17.4 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EWM28582.1 - 0.082 11.7 0.0 0.29 9.9 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 EWM28582.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EWM28582.1 - 0.17 11.2 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like AAA_32 PF13654.6 EWM28584.1 - 0.11 11.2 1.9 0.1 11.3 0.3 1.6 2 0 0 2 2 2 0 AAA domain AAA_32 PF13654.6 EWM28585.1 - 0.14 10.9 2.7 0.084 11.6 0.4 1.6 2 0 0 2 2 2 0 AAA domain GWT1 PF06423.12 EWM28586.1 - 1.1e-26 93.8 3.8 1.1e-26 93.8 3.8 2.6 2 0 0 2 2 2 1 GWT1 Pkinase PF00069.25 EWM28587.1 - 2.8e-53 181.0 0.0 1.8e-37 129.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EWM28587.1 - 2.8e-30 105.5 0.0 5.3e-24 84.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 EWM28587.1 - 6.2e-18 65.0 0.1 1.1e-17 64.2 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Guanylate_cyc PF00211.20 EWM28587.1 - 1.8e-15 57.0 0.0 2.8e-12 46.7 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain APH PF01636.23 EWM28587.1 - 0.015 15.2 1.9 0.022 14.7 0.1 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EWM28587.1 - 0.055 12.8 0.1 2.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Kinase-like FAM60A PF15396.6 EWM28587.1 - 2.1 8.3 8.2 3 7.8 0.0 2.9 2 0 0 2 2 2 0 Protein Family FAM60A G-patch PF01585.23 EWM28589.1 - 8.5e-12 44.8 0.0 1.6e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EWM28589.1 - 0.00076 19.5 0.5 0.0028 17.7 0.0 2.2 2 0 0 2 2 2 1 G-patch domain ubiquitin PF00240.23 EWM28590.1 - 1.7e-34 117.4 0.6 2.7e-34 116.7 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 EWM28590.1 - 6.2e-27 93.2 12.0 1.1e-26 92.5 12.0 1.4 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 EWM28590.1 - 1.9e-16 59.6 0.7 3.1e-16 58.9 0.7 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EWM28590.1 - 4.2e-06 27.1 0.4 2.6e-05 24.6 0.1 2.3 2 1 0 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EWM28590.1 - 0.0036 17.2 0.0 0.0056 16.6 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EWM28590.1 - 0.0078 16.3 0.0 0.021 14.9 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EWM28590.1 - 0.012 15.9 0.4 0.021 15.2 0.0 1.6 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 EWM28590.1 - 0.019 15.5 0.0 0.029 14.9 0.0 1.4 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EWM28590.1 - 0.06 13.4 0.8 13 5.9 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain ABC1 PF03109.16 EWM28591.1 - 6.1e-26 90.9 0.0 1.2e-25 90.0 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EWM28591.1 - 0.00075 19.5 5.2 0.00085 19.3 0.3 2.9 3 1 1 4 4 4 1 Phosphotransferase enzyme family Pkinase PF00069.25 EWM28591.1 - 0.17 11.2 0.0 0.59 9.4 0.0 1.8 3 0 0 3 3 3 0 Protein kinase domain ABC_membrane PF00664.23 EWM28592.1 - 7.4e-52 176.7 13.2 8.3e-30 104.4 1.3 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EWM28592.1 - 3.5e-47 160.4 0.0 1.9e-26 93.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 EWM28592.1 - 2.5e-07 31.2 0.2 0.038 14.4 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 EWM28592.1 - 8.4e-07 28.6 0.1 0.59 9.5 0.1 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EWM28592.1 - 6.1e-06 26.3 0.1 0.076 13.1 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EWM28592.1 - 5.8e-05 22.8 0.0 0.6 9.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EWM28592.1 - 5.9e-05 23.7 0.0 0.2 12.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EWM28592.1 - 8.1e-05 22.9 0.1 0.39 11.0 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 EWM28592.1 - 8.5e-05 23.0 0.2 0.4 11.1 0.1 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 EWM28592.1 - 0.00013 21.9 0.0 0.4 10.4 0.0 3.0 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EWM28592.1 - 0.00025 21.0 0.0 0.42 10.5 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase DUF815 PF05673.13 EWM28592.1 - 0.0048 16.1 0.1 3.2 6.8 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF815) AAA_7 PF12775.7 EWM28592.1 - 0.0052 16.3 0.0 3.1 7.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region ATPase_2 PF01637.18 EWM28592.1 - 0.0097 15.8 0.0 0.047 13.6 0.0 2.0 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Adeno_IVa2 PF02456.15 EWM28592.1 - 0.015 14.1 0.1 0.16 10.7 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein DUF87 PF01935.17 EWM28592.1 - 0.015 15.4 0.1 1.5 8.8 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain RNA_helicase PF00910.22 EWM28592.1 - 0.016 15.6 0.0 0.39 11.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase T2SSE PF00437.20 EWM28592.1 - 0.016 14.3 0.0 2.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.12 EWM28592.1 - 0.019 14.9 0.0 1.6 8.6 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Dynamin_N PF00350.23 EWM28592.1 - 0.025 14.6 0.1 4.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Dynamin family AAA_24 PF13479.6 EWM28592.1 - 0.034 13.9 0.0 4.3 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EWM28592.1 - 0.038 13.7 0.2 6.3 6.5 0.0 2.8 3 0 0 3 3 2 0 IstB-like ATP binding protein AAA_25 PF13481.6 EWM28592.1 - 0.068 12.7 1.7 0.54 9.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 EWM28592.1 - 0.074 12.2 0.2 21 4.2 0.0 3.3 4 0 0 4 4 4 0 NB-ARC domain AAA_5 PF07728.14 EWM28592.1 - 0.079 13.0 0.1 3 7.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EWM28592.1 - 0.08 12.7 1.1 2.3 7.9 0.9 2.9 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EWM28592.1 - 0.18 11.1 0.0 2 7.6 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin RseC_MucC PF04246.12 EWM28592.1 - 1.6 8.7 3.5 2.3 8.2 0.2 3.0 3 0 0 3 3 2 0 Positive regulator of sigma(E), RseC/MucC eIF-5a PF01287.20 EWM28594.1 - 5.6e-23 80.8 0.0 8.4e-23 80.3 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 EWM28594.1 - 1.8e-05 24.6 0.7 2.7e-05 24.1 0.7 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain 6PGD PF00393.19 EWM28595.1 - 8.6e-126 419.2 0.0 1e-125 418.9 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EWM28595.1 - 8.8e-44 149.5 0.0 1.3e-43 148.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 EWM28595.1 - 0.077 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pep_deformylase PF01327.21 EWM28596.1 - 1.2e-49 167.9 0.0 1.6e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase MTS PF05175.14 EWM28597.1 - 0.0011 18.6 0.5 0.088 12.3 0.1 2.8 2 1 0 2 2 2 1 Methyltransferase small domain Met_10 PF02475.16 EWM28597.1 - 0.047 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein Cons_hypoth95 PF03602.15 EWM28597.1 - 0.093 12.4 0.0 14 5.3 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical protein 95 TPR_2 PF07719.17 EWM28598.1 - 0.00063 19.7 10.0 2.6 8.4 0.2 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 EWM28598.1 - 0.0024 18.1 16.6 0.13 12.6 0.4 4.5 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EWM28598.1 - 0.0056 16.6 7.3 0.45 10.6 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EWM28598.1 - 0.02 14.7 3.2 15 5.6 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 EWM28598.1 - 0.035 14.0 14.9 7.8 6.5 0.2 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EWM28598.1 - 0.035 14.6 1.0 0.23 11.9 0.2 2.3 2 1 0 2 2 2 0 Alkyl sulfatase dimerisation TPR_8 PF13181.6 EWM28598.1 - 0.075 13.3 0.3 15 6.1 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat ABC2_membrane PF01061.24 EWM28599.1 - 7.8e-30 103.9 19.0 7.8e-30 103.9 19.0 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 EWM28599.1 - 4.5e-26 92.0 0.1 1.2e-25 90.6 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EWM28599.1 - 1.6e-05 24.9 0.0 0.18 11.6 0.0 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EWM28599.1 - 0.00023 21.6 0.5 0.00049 20.5 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 EWM28599.1 - 0.00044 19.7 0.0 0.004 16.6 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EWM28599.1 - 0.0012 18.8 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EWM28599.1 - 0.0064 16.2 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EWM28599.1 - 0.038 14.2 0.3 0.1 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EWM28599.1 - 0.059 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF1666 PF07891.12 EWM28599.1 - 0.13 12.0 0.4 0.28 10.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1666) AAA_18 PF13238.6 EWM28599.1 - 0.17 12.4 0.0 0.36 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain SR-25 PF10500.9 EWM28599.1 - 0.8 9.3 6.5 1.2 8.7 6.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Zip PF02535.22 EWM28599.1 - 0.9 8.7 8.3 0.2 10.8 1.0 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter ABC2_membrane_3 PF12698.7 EWM28599.1 - 0.92 8.6 27.7 0.058 12.5 22.9 1.4 2 0 0 2 2 2 0 ABC-2 family transporter protein Aa_trans PF01490.18 EWM28600.1 - 1.8 7.2 2.7 2.5 6.7 2.7 1.1 1 0 0 1 1 1 0 Transmembrane amino acid transporter protein Aa_trans PF01490.18 EWM28601.1 - 1.6 7.4 2.7 2.1 7.0 2.7 1.1 1 0 0 1 1 1 0 Transmembrane amino acid transporter protein Enolase_C PF00113.22 EWM28602.1 - 1.2e-151 504.1 0.1 1.2e-151 504.1 0.1 1.4 2 0 0 2 2 2 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EWM28602.1 - 9.9e-57 190.7 0.6 2e-56 189.7 0.6 1.6 1 0 0 1 1 1 1 Enolase, N-terminal domain MAAL_C PF07476.11 EWM28602.1 - 9.6e-07 28.2 1.1 1.4e-06 27.7 0.1 1.7 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_C PF13378.6 EWM28602.1 - 2.9e-06 27.0 0.0 4.6e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like PEMT PF04191.13 EWM28603.1 - 1.1e-11 45.0 7.1 1.4e-11 44.8 2.6 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 EWM28603.1 - 0.048 14.1 2.0 0.054 13.9 0.5 2.0 2 1 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family HTH_9 PF08221.11 EWM28604.1 - 9.7e-14 51.2 0.3 3.1e-09 36.8 0.0 4.1 4 0 0 4 4 4 2 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.13 EWM28604.1 - 0.0001 22.2 1.7 0.0031 17.3 0.1 3.1 2 1 0 2 2 2 1 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.17 EWM28604.1 - 0.014 15.3 0.5 0.034 14.0 0.5 1.7 1 0 0 1 1 1 0 TFIIE alpha subunit DUF389 PF04087.14 EWM28605.1 - 0.0073 16.4 0.6 0.036 14.1 0.8 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF389) DUF952 PF06108.12 EWM28605.1 - 0.14 12.1 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF952) DUF2721 PF11026.8 EWM28605.1 - 0.29 11.0 2.3 0.75 9.7 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) RelA_SpoT PF04607.17 EWM28606.1 - 2e-21 76.4 0.0 2.2e-15 56.9 0.0 2.4 2 0 0 2 2 2 2 Region found in RelA / SpoT proteins HD_4 PF13328.6 EWM28606.1 - 1.7e-10 40.8 1.6 1.7e-10 40.8 1.6 1.8 2 0 0 2 2 2 1 HD domain EF-hand_5 PF13202.6 EWM28606.1 - 1.6e-06 27.3 0.0 3.9e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EWM28606.1 - 4.8e-06 26.9 0.1 1.4e-05 25.5 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EWM28606.1 - 3.4e-05 23.1 0.0 7.6e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EWM28606.1 - 0.001 18.8 0.0 0.0037 17.1 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain ACC_central PF08326.12 EWM28606.1 - 0.12 10.6 0.0 0.19 9.9 0.0 1.2 1 0 0 1 1 1 0 Acetyl-CoA carboxylase, central region EF-hand_8 PF13833.6 EWM28606.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair AAA_28 PF13521.6 EWM28608.1 - 3.2e-26 92.5 0.0 5.5e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain DAP3 PF10236.9 EWM28608.1 - 0.0072 15.5 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 Thymidylate_kin PF02223.17 EWM28608.1 - 0.014 15.1 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase KTI12 PF08433.10 EWM28608.1 - 0.021 14.3 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_30 PF13604.6 EWM28608.1 - 0.08 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 EWM28608.1 - 0.15 11.0 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB T2SSE PF00437.20 EWM28608.1 - 0.17 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein HLH PF00010.26 EWM28609.1 - 3.9e-08 33.1 1.4 8.1e-08 32.1 1.4 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_4 PF08448.10 EWM28609.1 - 0.00057 20.1 0.4 0.0013 18.9 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 EWM28609.1 - 0.0012 19.1 0.0 0.002 18.3 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 EWM28609.1 - 0.0064 16.5 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 EWM28609.1 - 0.1 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 PAS fold PAS PF00989.25 EWM28609.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 PAS fold HLH PF00010.26 EWM28610.1 - 3.7e-08 33.2 1.4 7.9e-08 32.1 1.4 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_4 PF08448.10 EWM28610.1 - 0.00054 20.2 0.4 0.0013 19.0 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 EWM28610.1 - 0.0012 19.1 0.0 0.002 18.4 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 EWM28610.1 - 0.0063 16.5 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 EWM28610.1 - 0.1 12.9 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 PAS fold PAS PF00989.25 EWM28610.1 - 0.11 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 PAS fold zf-U1 PF06220.12 EWM28611.1 - 9.8e-10 38.0 2.0 2e-09 37.0 0.6 2.0 2 0 0 2 2 2 1 U1 zinc finger Mito_fiss_reg PF05308.11 EWM28611.1 - 4.1e-06 27.1 4.1 0.0023 18.1 1.4 2.3 2 0 0 2 2 2 2 Mitochondrial fission regulator CRAL_TRIO PF00650.20 EWM28612.1 - 6.9e-29 100.6 0.0 1e-28 100.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EWM28612.1 - 0.0036 17.5 0.0 0.0059 16.8 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain FA_hydroxylase PF04116.13 EWM28613.1 - 2.4e-23 82.9 10.6 2.4e-23 82.9 10.6 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily GWT1 PF06423.12 EWM28613.1 - 0.12 12.5 0.1 0.27 11.3 0.1 1.6 1 0 0 1 1 1 0 GWT1 PUB PF09409.10 EWM28614.1 - 3.9e-12 45.9 0.0 8.9e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 PUB domain Asp-B-Hydro_N PF05279.11 EWM28614.1 - 2 8.4 10.9 3 7.8 10.9 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4033 PF13225.6 EWM28615.1 - 5.6e-28 96.8 0.1 1.1e-27 95.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4033) RCC1 PF00415.18 EWM28616.1 - 3.4e-49 165.2 35.5 3e-12 46.9 0.1 7.8 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EWM28616.1 - 3e-33 112.9 25.0 1.2e-09 37.7 0.3 6.9 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.6 EWM28616.1 - 7.7e-13 48.7 0.3 3.4e-12 46.6 0.4 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EWM28616.1 - 8.1e-10 39.2 0.0 4e-09 36.9 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 EWM28616.1 - 5.6e-07 29.7 2.0 0.00035 20.9 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 EWM28616.1 - 1e-06 28.6 0.9 0.0037 17.6 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat zf-met PF12874.7 EWM28616.1 - 1.1e-05 25.6 2.3 3.1e-05 24.2 2.3 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Ank_5 PF13857.6 EWM28616.1 - 1.1e-05 25.6 1.3 0.036 14.4 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) zf-C2H2_jaz PF12171.8 EWM28616.1 - 5.4e-05 23.4 0.8 0.0001 22.5 0.8 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding SUKH-3 PF14433.6 EWM28616.1 - 7.2 7.1 8.9 15 6.0 0.0 4.1 4 1 1 5 5 5 0 SUKH-3 immunity protein Amidase PF01425.21 EWM28617.1 - 2e-90 304.0 0.0 1.7e-71 241.5 0.7 2.2 2 0 0 2 2 2 2 Amidase Amidase PF01425.21 EWM28618.1 - 2e-90 304.0 0.0 1.7e-71 241.5 0.7 2.2 2 0 0 2 2 2 2 Amidase UPF0029 PF01205.19 EWM28619.1 - 9.4e-31 106.3 0.1 1.7e-30 105.5 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 EWM28619.1 - 6.9e-13 48.9 0.0 1.1e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 RWD domain DUF1428 PF07237.11 EWM28619.1 - 0.13 12.5 0.1 0.51 10.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1428) CBFD_NFYB_HMF PF00808.23 EWM28620.1 - 8.3e-18 64.4 2.7 1.4e-17 63.7 2.7 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EWM28620.1 - 3.4e-10 40.4 1.6 3.8e-10 40.2 0.5 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-W PF15510.6 EWM28620.1 - 0.00096 19.3 0.0 0.0016 18.6 0.0 1.3 1 0 0 1 1 1 1 CENP-W protein CENP-T_C PF15511.6 EWM28620.1 - 0.0044 17.1 0.6 0.0072 16.4 0.6 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Hamartin PF04388.12 EWM28620.1 - 0.089 11.4 7.1 0.097 11.3 7.1 1.0 1 0 0 1 1 1 0 Hamartin protein GCD14 PF08704.10 EWM28621.1 - 4.1e-67 226.5 0.2 1.8e-37 129.4 0.1 2.8 2 1 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit GCD14_N PF14801.6 EWM28621.1 - 4.4e-08 32.9 0.2 9.2e-08 31.8 0.2 1.6 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_31 PF13847.6 EWM28621.1 - 0.00043 20.1 0.0 0.00082 19.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EWM28621.1 - 0.00047 20.0 0.0 0.00074 19.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 EWM28621.1 - 0.0025 18.5 0.0 0.0056 17.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EWM28621.1 - 0.09 12.1 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase zf-RING_2 PF13639.6 EWM28622.1 - 7.7e-05 22.9 13.9 7.7e-05 22.9 13.9 2.8 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 EWM28622.1 - 0.00022 21.0 14.5 0.00022 21.0 14.5 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EWM28622.1 - 0.0022 17.8 14.0 0.0022 17.8 14.0 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EWM28622.1 - 0.0069 16.4 10.9 0.0069 16.4 10.9 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EWM28622.1 - 0.024 14.8 16.0 0.024 14.8 16.0 2.5 2 1 2 4 4 4 0 zinc finger of C3HC4-type, RING DUF1178 PF06676.11 EWM28622.1 - 0.08 13.3 1.6 0.16 12.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) zf-RING_6 PF14835.6 EWM28622.1 - 2.8 7.9 12.0 0.5 10.3 7.6 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein TackOD1 PF18551.1 EWM28622.1 - 5.4 6.6 17.4 7.9 6.1 10.0 2.3 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 Prok-RING_4 PF14447.6 EWM28622.1 - 6.1 6.8 22.0 0.081 12.8 13.4 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Ribosomal_L36 PF00444.18 EWM28624.1 - 3e-19 68.9 3.9 4.5e-19 68.4 3.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L36 Crust_neurohorm PF01147.17 EWM28624.1 - 0.018 14.8 0.9 0.036 13.9 0.9 1.5 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family TPP_enzyme_M PF00205.22 EWM28626.1 - 1.4e-23 83.1 0.0 2.6e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EWM28626.1 - 3.4e-20 72.4 2.1 2.4e-19 69.6 0.0 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.18 EWM28626.1 - 2e-19 69.8 0.2 5.1e-19 68.5 0.2 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain DXP_synthase_N PF13292.6 EWM28626.1 - 0.0045 16.2 0.0 0.0077 15.5 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_N PF02776.18 EWM28627.1 - 1.3e-32 112.8 0.0 2.6e-32 111.8 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EWM28627.1 - 9.7e-24 83.7 0.0 1.7e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Inositol_P PF00459.25 EWM28628.1 - 5.7e-50 170.3 0.0 7.2e-50 170.0 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 EWM28628.1 - 0.00048 19.7 0.0 0.00079 19.0 0.0 1.3 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain FKBP_C PF00254.28 EWM28629.1 - 3.7e-20 72.1 0.0 5.4e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase MTS PF05175.14 EWM28631.1 - 2.6e-05 23.9 0.0 7e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EWM28631.1 - 0.013 16.2 0.0 0.033 14.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain PAC2 PF09754.9 EWM28631.1 - 0.055 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 PAC2 family PrmA PF06325.13 EWM28631.1 - 0.08 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Acid_PPase PF12689.7 EWM28632.1 - 5.5e-51 172.8 0.0 6.9e-51 172.4 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase NIF PF03031.18 EWM28632.1 - 7.2e-07 29.1 0.0 1e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Chlamy_scaf PF09675.10 EWM28632.1 - 0.051 13.9 0.0 0.11 12.8 0.0 1.5 1 1 0 1 1 1 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) DUF2608 PF11019.8 EWM28632.1 - 0.12 11.8 0.1 0.86 9.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) Hydrolase PF00702.26 EWM28632.1 - 0.14 12.4 0.0 0.69 10.1 0.0 1.8 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Pre-PUA PF17832.1 EWM28633.1 - 1.4e-27 96.2 0.0 2.4e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 EWM28633.1 - 1.6e-14 53.6 0.1 3.1e-14 52.7 0.1 1.5 1 0 0 1 1 1 1 PUA domain Sulfotransfer_1 PF00685.27 EWM28634.1 - 3.7e-13 49.6 0.0 6.7e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EWM28634.1 - 5.2e-10 40.1 0.2 7.4e-07 29.8 0.2 3.2 1 1 0 1 1 1 1 Sulfotransferase family Asp_Arg_Hydrox PF05118.15 EWM28634.1 - 1.3e-08 34.8 0.1 3e-08 33.6 0.1 1.6 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase PAP1 PF08601.10 EWM28634.1 - 1.1 8.9 12.4 1.7 8.3 12.4 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Mem_trans PF03547.18 EWM28636.1 - 3.1e-30 104.9 0.0 7.6e-30 103.6 0.0 1.5 1 1 0 1 1 1 1 Membrane transport protein CAP_GLY PF01302.25 EWM28637.1 - 2.5e-13 49.8 0.1 5.1e-13 48.8 0.1 1.5 1 1 0 1 1 1 1 CAP-Gly domain UPF0121 PF03661.13 EWM28638.1 - 2.9e-22 79.2 1.5 4.5e-22 78.6 1.5 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) TPR_2 PF07719.17 EWM28638.1 - 2.6e-10 39.6 6.8 0.00011 22.0 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EWM28638.1 - 2.3e-08 33.5 1.8 0.0076 16.0 0.0 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EWM28638.1 - 1.3e-06 28.0 1.8 0.044 13.5 0.2 3.8 2 1 2 4 4 4 2 TPR repeat TPR_14 PF13428.6 EWM28638.1 - 0.0018 18.9 0.6 0.0018 18.9 0.6 4.1 4 1 1 5 5 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EWM28638.1 - 0.0028 18.1 3.9 0.076 13.5 0.5 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EWM28638.1 - 0.017 15.3 1.6 8.6 6.9 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EWM28638.1 - 0.028 14.7 8.4 1.3 9.3 1.4 3.8 2 1 2 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.17 EWM28638.1 - 0.033 14.6 6.3 0.036 14.5 0.6 3.0 2 1 1 3 3 3 0 Bacterial transcriptional activator domain TPR_16 PF13432.6 EWM28638.1 - 0.065 13.9 15.0 0.46 11.2 2.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 EWM28638.1 - 0.081 13.1 2.4 2.5 8.3 0.8 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EWM28638.1 - 0.12 13.1 1.2 26 5.8 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-CGNR PF11706.8 EWM28639.1 - 0.05 13.5 5.0 4 7.4 0.0 2.7 2 0 0 2 2 2 0 CGNR zinc finger FHA PF00498.26 EWM28640.1 - 5.9e-10 39.4 0.0 1.1e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EWM28640.1 - 0.00015 22.1 0.0 0.00084 19.6 0.0 2.4 3 1 0 3 3 3 1 Inner membrane component of T3SS, cytoplasmic domain tRNA_int_end_N2 PF12928.7 EWM28642.1 - 2.1e-11 43.8 0.0 4.9e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term Ribosomal_S8e PF01201.22 EWM28642.1 - 0.15 12.2 0.6 0.33 11.1 0.6 1.5 1 0 0 1 1 1 0 Ribosomal protein S8e Snf7 PF03357.21 EWM28644.1 - 3.9e-20 72.2 16.8 4.8e-20 71.9 16.8 1.1 1 0 0 1 1 1 1 Snf7 DUF884 PF05959.11 EWM28644.1 - 0.0096 15.6 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF884) YlqD PF11068.8 EWM28644.1 - 0.25 11.7 7.8 0.29 11.5 6.5 1.7 1 1 1 2 2 2 0 YlqD protein Allexi_40kDa PF05549.11 EWM28644.1 - 0.28 10.7 3.1 0.3 10.6 2.4 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein DUF948 PF06103.11 EWM28644.1 - 1.7 9.0 4.2 14 6.0 0.7 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) LdpA_C PF12617.8 EWM28645.1 - 4e-34 117.8 0.0 3.9e-33 114.6 0.0 2.5 2 1 0 2 2 2 1 Iron-Sulfur binding protein C terminal FG-GAP PF01839.23 EWM28646.1 - 2.5e-31 107.4 51.2 2.7e-08 33.8 4.7 6.6 7 0 0 7 7 7 5 FG-GAP repeat VCBS PF13517.6 EWM28646.1 - 9e-17 61.4 25.8 1e-07 32.4 1.2 5.3 2 1 4 6 6 6 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF4719 PF15843.5 EWM28646.1 - 0.075 13.1 0.5 0.19 11.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4719) FG-GAP_2 PF14312.6 EWM28646.1 - 0.12 12.7 19.8 1 9.7 0.1 6.1 5 1 0 5 5 5 0 FG-GAP repeat TcdB_toxin_midN PF12256.8 EWM28646.1 - 0.19 11.1 8.2 3.6 6.9 0.0 4.7 5 0 0 5 5 5 0 Insecticide toxin TcdB middle/N-terminal region AnfO_nitrog PF09582.10 EWM28647.1 - 0.21 10.9 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) FtsJ PF01728.19 EWM28648.1 - 8.8e-25 87.8 0.0 2.8e-24 86.2 0.0 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase DUF2408 PF10303.9 EWM28651.1 - 4.8e-23 82.2 2.1 9.2e-10 39.2 0.1 3.3 1 1 2 3 3 3 3 Protein of unknown function (DUF2408) Snapin_Pallidin PF14712.6 EWM28651.1 - 5.4e-05 23.5 1.8 0.032 14.7 0.0 3.6 4 1 0 4 4 4 1 Snapin/Pallidin DUF2730 PF10805.8 EWM28651.1 - 0.0081 16.2 2.1 0.41 10.8 0.2 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2730) COG2 PF06148.11 EWM28651.1 - 0.0098 16.0 1.8 2.3 8.3 0.0 3.2 4 0 0 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 Helo_like_N PF17111.5 EWM28651.1 - 0.016 14.6 1.3 1.8 7.9 0.3 2.4 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins ABC_tran_CTD PF16326.5 EWM28651.1 - 0.032 14.5 5.3 4.3 7.7 0.1 3.4 3 0 0 3 3 3 0 ABC transporter C-terminal domain EzrA PF06160.12 EWM28651.1 - 0.04 12.1 3.7 0.2 9.8 0.5 2.7 3 0 0 3 3 3 0 Septation ring formation regulator, EzrA YabA PF06156.13 EWM28651.1 - 0.069 13.8 4.1 0.98 10.1 0.1 3.3 2 1 1 3 3 3 0 Initiation control protein YabA SPATA1_C PF15743.5 EWM28651.1 - 0.11 12.6 2.0 0.95 9.5 0.5 2.7 3 0 0 3 3 3 0 Spermatogenesis-associated C-terminus TRPM_tetra PF16519.5 EWM28651.1 - 0.11 12.6 1.4 0.42 10.8 0.7 2.2 2 0 0 2 2 2 0 Tetramerisation domain of TRPM Spc7 PF08317.11 EWM28651.1 - 0.21 10.4 8.8 0.6 8.9 1.1 2.9 1 1 2 3 3 3 0 Spc7 kinetochore protein XhlA PF10779.9 EWM28651.1 - 0.29 11.4 2.5 4.2 7.7 0.6 2.4 2 0 0 2 2 2 0 Haemolysin XhlA DUF4795 PF16043.5 EWM28651.1 - 0.4 10.2 4.0 8.2 6.0 0.2 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) KBP_C PF12309.8 EWM28653.1 - 2.2e-63 214.9 0.0 7.7e-63 213.2 0.0 1.7 1 1 0 1 1 1 1 KIF-1 binding protein C terminal MAGE_N PF12440.8 EWM28653.1 - 9.4 7.0 6.4 2.2 9.0 0.6 2.8 3 0 0 3 3 3 0 Melanoma associated antigen family N terminal Glyco_transf_8 PF01501.20 EWM28655.1 - 5e-13 49.2 0.0 5.4e-12 45.8 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 EWM28655.1 - 0.056 12.8 0.0 0.074 12.4 0.0 1.1 1 0 0 1 1 1 0 Mannosyltransferase putative Rpr2 PF04032.16 EWM28656.1 - 2.3e-10 40.6 0.9 4.9e-10 39.6 0.9 1.6 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Aldo_ket_red PF00248.21 EWM28657.1 - 1.3e-53 182.1 0.0 1.6e-53 181.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family MG2 PF01835.19 EWM28658.1 - 0.023 15.1 0.2 3 8.4 0.0 3.1 3 0 0 3 3 3 0 MG2 domain UQ_con PF00179.26 EWM28659.1 - 1.4e-37 128.4 0.0 2.2e-37 127.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EWM28659.1 - 0.064 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B Spt20 PF12090.8 EWM28659.1 - 0.14 11.7 4.2 0.2 11.3 4.2 1.2 1 0 0 1 1 1 0 Spt20 family SRP-alpha_N PF04086.13 EWM28659.1 - 1 9.2 4.2 1.5 8.7 4.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PPR_2 PF13041.6 EWM28661.1 - 4.7e-19 68.3 0.1 1.5e-08 34.7 0.0 4.1 3 1 1 4 4 4 4 PPR repeat family PPR PF01535.20 EWM28661.1 - 2e-16 59.0 1.9 0.00051 20.1 0.0 4.5 5 0 0 5 5 5 3 PPR repeat PPR_1 PF12854.7 EWM28661.1 - 1.6e-13 50.1 0.0 0.00093 18.8 0.0 4.7 5 0 0 5 5 5 3 PPR repeat PPR_3 PF13812.6 EWM28661.1 - 2.2e-12 46.9 0.0 4.6e-07 29.8 0.0 3.8 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_long PF17177.4 EWM28661.1 - 1.4e-06 27.8 0.1 0.0038 16.6 0.0 2.7 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP Clathrin PF00637.20 EWM28661.1 - 7.9e-05 22.6 0.0 0.014 15.2 0.0 2.9 2 1 0 2 2 2 1 Region in Clathrin and VPS TA_inhibitor PF17574.2 EWM28661.1 - 0.02 14.9 0.1 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 Inhibitor of toxin/antitoxin system (Gp4.5) DEAD PF00270.29 EWM28662.1 - 5.2e-22 78.4 0.0 8.8e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EWM28662.1 - 1.2e-13 51.5 0.0 1.8e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Sec63 PF02889.16 EWM28662.1 - 4.2e-10 39.2 0.0 8.5e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 Sec63 Brl domain Helicase_C PF00271.31 EWM28662.1 - 4.9e-08 33.3 0.0 4.9e-07 30.1 0.0 2.5 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EWM28662.1 - 0.0003 21.1 0.0 0.0008 19.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Prok-RING_1 PF14446.6 EWM28663.1 - 0.00052 19.9 5.8 0.0014 18.6 5.8 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-RING_2 PF13639.6 EWM28663.1 - 0.00053 20.3 7.7 0.00053 20.3 7.7 1.9 2 0 0 2 2 2 1 Ring finger domain PHD PF00628.29 EWM28663.1 - 0.0053 16.6 5.2 0.012 15.5 5.2 1.6 1 0 0 1 1 1 1 PHD-finger SWIM PF04434.17 EWM28663.1 - 0.012 15.3 0.1 0.028 14.1 0.1 1.6 1 0 0 1 1 1 0 SWIM zinc finger FANCL_C PF11793.8 EWM28663.1 - 0.087 13.0 2.1 0.2 11.8 2.1 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain TPR_12 PF13424.6 EWM28664.1 - 9e-10 38.7 12.3 1.5e-05 25.1 1.0 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 EWM28664.1 - 1.5e-08 33.9 0.5 6.3e-07 28.8 0.1 2.4 2 0 0 2 2 2 1 SHNi-TPR TPR_1 PF00515.28 EWM28664.1 - 5.7e-07 29.1 6.5 0.0011 18.7 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EWM28664.1 - 6e-06 26.0 7.4 0.02 15.0 0.1 4.4 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EWM28664.1 - 5e-05 23.0 8.9 0.063 13.2 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EWM28664.1 - 6.2e-05 22.7 2.4 0.27 11.4 0.1 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EWM28664.1 - 0.00052 20.0 3.7 0.013 15.7 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EWM28664.1 - 0.0037 17.7 1.3 1.6 9.3 0.2 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EWM28664.1 - 0.0064 17.1 4.8 1.5 9.6 0.1 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EWM28664.1 - 0.0066 16.7 1.1 22 5.7 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EWM28664.1 - 0.015 15.5 0.1 0.92 9.8 0.1 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EWM28664.1 - 0.019 15.8 3.9 4.3 8.4 0.1 3.5 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EWM28664.1 - 0.019 14.6 0.2 17 5.2 0.0 3.4 2 1 1 3 3 3 0 TPR repeat TPR_9 PF13371.6 EWM28664.1 - 0.047 13.8 1.8 13 6.1 0.4 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 EWM28664.1 - 0.1 13.3 0.0 45 5.1 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 EWM28664.1 - 1.2 9.9 6.7 4.5 8.0 0.0 3.6 3 1 0 3 3 2 0 Tetratricopeptide repeat Chloroa_b-bind PF00504.21 EWM28665.1 - 6.2e-36 124.4 0.1 9.5e-36 123.8 0.1 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein RNA_pol_Rpb1_2 PF00623.20 EWM28665.1 - 2.5e-21 76.6 0.0 4.3e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 EWM28665.1 - 1.4e-16 60.7 0.0 3.6e-16 59.4 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 1 adh_short PF00106.25 EWM28666.1 - 5.3e-46 156.5 0.1 7.7e-46 156.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EWM28666.1 - 1.9e-27 96.3 0.0 2.9e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM28666.1 - 1.8e-09 37.7 0.1 3e-09 37.1 0.1 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EWM28666.1 - 2.3e-07 30.5 0.0 1.2e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) DSPc PF00782.20 EWM28667.1 - 4.7e-14 52.3 0.0 6.9e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EWM28667.1 - 0.0026 18.0 0.4 0.005 17.1 0.4 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 EWM28667.1 - 0.059 12.9 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EWM28667.1 - 0.074 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate V-ATPase_G PF03179.15 EWM28668.1 - 2.7e-19 69.6 6.8 2.2e-16 60.3 0.9 2.2 2 0 0 2 2 2 2 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 EWM28668.1 - 0.67 10.1 5.2 4.2 7.5 0.3 2.4 2 1 0 2 2 2 0 ATP synthase B/B' CF(0) SUI1 PF01253.22 EWM28669.1 - 2.1e-19 69.8 0.0 3.4e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 Rab5ip PF07019.12 EWM28670.1 - 0.02 15.5 0.4 0.038 14.6 0.4 1.4 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) zf-C3HC PF07967.13 EWM28671.1 - 5.6e-27 94.4 0.2 2.8e-21 75.9 1.7 3.2 2 1 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 EWM28671.1 - 0.00011 22.3 4.6 0.32 11.2 0.0 3.9 3 1 0 3 3 3 3 Rsm1-like Sgf11 PF08209.11 EWM28671.1 - 0.11 12.1 1.4 0.18 11.4 0.1 2.1 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) REV1_C PF16727.5 EWM28671.1 - 0.34 11.3 1.8 15 6.1 0.0 2.5 2 0 0 2 2 2 0 DNA repair protein REV1 C-terminal domain Cys_Met_Meta_PP PF01053.20 EWM28673.1 - 1.1e-142 475.1 0.0 1.2e-142 474.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EWM28673.1 - 7.7e-05 22.2 0.7 0.001 18.5 0.7 2.5 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EWM28673.1 - 0.034 13.1 0.2 0.12 11.3 0.0 1.8 2 0 0 2 2 2 0 Aminotransferase class-V AA_permease_2 PF13520.6 EWM28674.1 - 5.8e-51 173.6 22.8 7.8e-51 173.2 22.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EWM28674.1 - 4.5e-23 81.6 22.2 6.7e-23 81.0 22.2 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 EWM28674.1 - 8e-08 32.2 8.8 8e-08 32.2 8.8 3.4 3 0 0 3 3 3 1 C-terminus of AA_permease Spore_permease PF03845.13 EWM28674.1 - 4.6e-06 25.7 7.6 8.4e-05 21.5 7.6 2.3 1 1 0 1 1 1 1 Spore germination protein Spindle_Spc25 PF08234.12 EWM28675.1 - 4.9e-22 77.9 0.3 9.1e-22 77.1 0.3 1.5 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 CCDC92 PF14916.6 EWM28675.1 - 0.0042 16.8 2.6 0.011 15.5 2.6 1.7 1 0 0 1 1 1 1 Coiled-coil domain of unknown function MAD PF05557.13 EWM28675.1 - 0.0061 15.0 12.6 0.0086 14.5 12.6 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Spc7 PF08317.11 EWM28675.1 - 0.0077 15.2 9.4 0.011 14.6 9.4 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 EWM28675.1 - 0.021 14.8 15.7 0.037 14.0 12.5 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RNAse_A_bac PF18431.1 EWM28675.1 - 0.071 14.1 0.6 0.18 12.8 0.3 1.8 1 1 1 2 2 2 0 Bacterial CdiA-CT RNAse A domain COG2 PF06148.11 EWM28675.1 - 0.092 12.8 3.6 0.082 13.0 1.4 1.9 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 PI3K_P85_iSH2 PF16454.5 EWM28675.1 - 0.33 10.5 10.0 0.99 9.0 10.0 1.7 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain EMP24_GP25L PF01105.24 EWM28675.1 - 0.42 10.5 4.2 0.53 10.2 2.0 2.0 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF4164 PF13747.6 EWM28675.1 - 0.55 10.5 20.1 0.23 11.7 7.9 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4164) SWI-SNF_Ssr4 PF08549.10 EWM28675.1 - 0.64 8.6 6.8 0.9 8.1 6.8 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) DUF724 PF05266.14 EWM28675.1 - 0.9 9.3 8.7 1.4 8.7 8.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Atg14 PF10186.9 EWM28675.1 - 1.3 8.0 10.8 0.97 8.5 9.5 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Nsp1_C PF05064.13 EWM28675.1 - 1.5 8.6 7.6 1.7 8.5 2.9 2.3 2 0 0 2 2 2 0 Nsp1-like C-terminal region APG6_N PF17675.1 EWM28675.1 - 1.8 9.1 22.9 0.9 10.1 17.0 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF5595 PF18077.1 EWM28675.1 - 2 8.6 5.3 12 6.1 1.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) Spc24 PF08286.11 EWM28675.1 - 6.2 7.1 9.7 1.9 8.8 2.2 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 MAPEG PF01124.18 EWM28676.1 - 6.3e-16 58.5 0.1 1.2e-15 57.6 0.1 1.4 1 1 0 1 1 1 1 MAPEG family ABA_GPCR PF12430.8 EWM28676.1 - 0.038 13.7 0.2 0.36 10.6 0.1 2.4 2 1 1 3 3 3 0 Abscisic acid G-protein coupled receptor Peptidase_S10 PF00450.22 EWM28677.1 - 3e-117 392.6 0.0 3.5e-117 392.3 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase EF_TS PF00889.19 EWM28678.1 - 1.2e-49 168.7 0.0 2.1e-49 168.0 0.0 1.4 1 1 0 1 1 1 1 Elongation factor TS Bromodomain PF00439.25 EWM28679.1 - 2e-13 50.2 0.0 4.1e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Bromodomain MSA-2c PF12238.8 EWM28679.1 - 0.59 10.1 9.3 0.67 9.9 8.3 1.6 2 0 0 2 2 2 0 Merozoite surface antigen 2c tRNA-synt_2d PF01409.20 EWM28680.1 - 1.2e-45 156.0 0.7 5.7e-45 153.7 0.7 2.0 1 1 0 1 1 1 1 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 EWM28680.1 - 2.2e-23 82.5 0.0 4.4e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain TauE PF01925.19 EWM28681.1 - 1.8e-26 93.3 26.5 9.4e-14 51.6 6.2 2.5 1 1 1 2 2 2 2 Sulfite exporter TauE/SafE Metal_resist PF13801.6 EWM28681.1 - 0.13 12.5 0.3 0.96 9.6 0.3 2.2 2 0 0 2 2 2 0 Heavy-metal resistance GDP_Man_Dehyd PF16363.5 EWM28682.1 - 9.5e-17 61.4 0.0 2.3e-16 60.1 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EWM28682.1 - 1.7e-12 47.3 0.0 2.4e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family VHL_C PF17211.3 EWM28682.1 - 0.1 12.7 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 VHL box domain RrnaAD PF00398.20 EWM28683.1 - 1.9e-56 191.1 0.1 2.3e-56 190.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EWM28683.1 - 1.1e-06 29.2 0.0 2.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM28683.1 - 0.0001 22.9 0.0 0.00021 21.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EWM28683.1 - 0.0011 18.5 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.19 EWM28683.1 - 0.0022 17.7 0.1 0.0035 17.1 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EWM28683.1 - 0.0093 15.5 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EWM28683.1 - 0.012 15.4 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 EWM28683.1 - 0.066 12.5 0.5 0.13 11.6 0.1 1.6 2 0 0 2 2 2 0 O-methyltransferase domain UPF0020 PF01170.18 EWM28683.1 - 0.068 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_23 PF13489.6 EWM28683.1 - 0.069 13.0 0.0 0.097 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EWM28683.1 - 0.11 13.2 0.0 0.23 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 EWM28683.1 - 0.15 11.7 0.0 0.34 10.5 0.0 1.5 2 0 0 2 2 2 0 Conserved hypothetical protein 95 BAR PF03114.18 EWM28684.1 - 6.8e-14 52.1 0.2 1.9e-13 50.6 0.2 1.7 1 1 0 1 1 1 1 BAR domain SH3_1 PF00018.28 EWM28684.1 - 1.3e-13 50.3 0.1 2.2e-13 49.6 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EWM28684.1 - 6.4e-13 48.3 0.1 1.1e-12 47.6 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EWM28684.1 - 6.1e-10 38.6 0.0 1.1e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain GHL10 PF02638.15 EWM28684.1 - 0.088 11.9 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase-like 10 Stathmin PF00836.19 EWM28684.1 - 0.2 11.6 1.7 0.4 10.6 1.7 1.5 1 0 0 1 1 1 0 Stathmin family Mito_fiss_reg PF05308.11 EWM28684.1 - 0.28 11.2 8.5 0.99 9.4 0.1 2.5 2 0 0 2 2 2 0 Mitochondrial fission regulator Occludin_ELL PF07303.13 EWM28684.1 - 0.37 11.5 5.6 0.55 11.0 2.1 2.5 3 0 0 3 3 3 0 Occludin homology domain KELK PF15796.5 EWM28684.1 - 0.62 10.5 5.7 0.19 12.2 1.0 2.5 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase CPSase_L_D2 PF02786.17 EWM28685.1 - 4.5e-76 255.0 0.1 7.8e-76 254.3 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 EWM28685.1 - 3.3e-67 226.1 0.0 5.1e-67 225.5 0.0 1.3 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 EWM28685.1 - 5.9e-37 126.6 0.2 1.7e-36 125.1 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EWM28685.1 - 2.4e-32 111.3 0.0 5.5e-32 110.1 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 EWM28685.1 - 2e-26 93.2 0.0 4e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 EWM28685.1 - 3.7e-18 65.1 3.4 1.3e-17 63.4 3.4 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp PF02222.22 EWM28685.1 - 5.7e-09 35.8 0.1 2.4e-08 33.7 0.1 2.0 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 EWM28685.1 - 1.1e-08 34.8 3.4 3.2e-06 26.9 0.3 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 EWM28685.1 - 1.4e-08 34.5 0.0 3.3e-08 33.3 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_ST PF14397.6 EWM28685.1 - 0.00011 21.6 0.0 0.0003 20.1 0.0 1.7 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp NQRA PF05896.11 EWM28685.1 - 0.00027 20.5 0.4 0.00049 19.6 0.4 1.3 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) HlyD_3 PF13437.6 EWM28685.1 - 0.00029 21.5 1.2 0.34 11.6 0.1 2.7 2 0 0 2 2 2 2 HlyD family secretion protein RimK PF08443.11 EWM28685.1 - 0.00048 19.8 0.0 0.002 17.7 0.0 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 EWM28685.1 - 0.0009 18.9 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EWM28685.1 - 0.0024 18.0 0.0 0.0097 16.0 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 EWM28685.1 - 0.013 14.7 0.3 0.087 12.0 0.1 2.1 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion DUF3182 PF11379.8 EWM28685.1 - 0.017 14.1 0.0 0.048 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3182) GARS_A PF01071.19 EWM28685.1 - 0.061 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GCV_H PF01597.19 EWM28685.1 - 0.19 11.6 0.0 13 5.7 0.1 2.5 2 0 0 2 2 2 0 Glycine cleavage H-protein Exo_endo_phos PF03372.23 EWM28686.1 - 2.7e-11 43.4 0.0 5.7e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1295 PF06966.12 EWM28688.1 - 1.7e-53 181.6 0.9 2.2e-53 181.2 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 EWM28688.1 - 0.00039 20.8 0.1 0.00039 20.8 0.1 2.3 3 0 0 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.14 EWM28688.1 - 0.0024 18.3 1.3 0.0062 16.9 0.0 2.3 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 EWM28688.1 - 0.036 14.1 0.0 0.085 12.8 0.0 1.6 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase Mcl1_mid PF12341.8 EWM28689.1 - 1.7e-74 250.9 0.0 4.3e-74 249.5 0.0 1.7 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 EWM28689.1 - 1.5e-11 44.6 1.1 0.0057 17.5 0.0 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM28689.1 - 7.1e-11 42.3 0.0 0.0023 18.2 0.0 4.7 3 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Glyoxalase_4 PF13669.6 EWM28689.1 - 0.11 12.7 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Mcl1_mid PF12341.8 EWM28690.1 - 1.3e-74 251.3 0.0 3.4e-74 249.9 0.0 1.7 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 EWM28690.1 - 1.2e-11 44.9 1.2 0.005 17.7 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM28690.1 - 4.5e-09 36.5 0.0 0.002 18.4 0.0 4.1 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Glyoxalase_4 PF13669.6 EWM28690.1 - 0.1 12.9 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MFS_1 PF07690.16 EWM28691.1 - 2.9e-21 75.8 21.6 1.8e-20 73.2 21.6 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily SPX PF03105.19 EWM28691.1 - 3.6e-10 40.3 9.4 0.00051 20.1 0.6 3.4 1 1 2 3 3 3 3 SPX domain Sugar_tr PF00083.24 EWM28691.1 - 5.7e-06 25.5 1.5 1.1e-05 24.6 1.5 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 EWM28691.1 - 1.2 7.3 5.7 1.2 7.3 0.1 2.5 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Myosin_head PF00063.21 EWM28692.1 - 1.7e-188 628.0 0.0 6.7e-125 417.9 0.0 3.1 2 1 0 2 2 2 2 Myosin head (motor domain) ATP-gua_Ptrans PF00217.19 EWM28692.1 - 1.7e-18 66.9 0.0 3.8e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 EWM28692.1 - 8.4e-08 32.5 0.0 3.1e-07 30.7 0.0 2.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain Myosin_N PF02736.19 EWM28692.1 - 0.00017 21.4 0.3 0.0004 20.2 0.3 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain RsgA_GTPase PF03193.16 EWM28692.1 - 0.048 13.6 0.1 0.45 10.4 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 EWM28692.1 - 0.063 13.6 0.0 0.37 11.1 0.0 2.4 1 0 0 1 1 1 0 AAA domain Hydantoinase_B PF02538.14 EWM28693.1 - 2.3e-204 679.6 0.0 3.6e-204 679.0 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EWM28693.1 - 5.1e-98 327.9 1.1 1e-97 326.9 1.1 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EWM28693.1 - 2.6e-59 199.9 0.1 3.4e-57 193.0 0.0 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region G-alpha PF00503.20 EWM28694.1 - 3.5e-100 335.6 4.0 5.8e-100 334.9 4.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EWM28694.1 - 1.2e-14 54.2 2.7 6.3e-11 42.0 0.4 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EWM28694.1 - 0.0039 16.6 3.4 0.12 11.7 0.3 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 EWM28694.1 - 0.03 14.0 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 EWM28694.1 - 0.039 14.2 1.9 5 7.4 0.2 2.7 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase adh_short PF00106.25 EWM28695.1 - 1.7e-47 161.4 0.1 2.1e-47 161.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EWM28695.1 - 1.6e-29 103.2 0.0 2.2e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM28695.1 - 2.2e-12 47.3 0.0 3.6e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EWM28695.1 - 3.1e-05 23.5 0.0 0.00037 20.0 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EWM28695.1 - 0.047 13.1 0.2 0.51 9.8 0.2 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family SOUL PF04832.12 EWM28696.1 - 1.5e-05 25.3 0.0 2.6e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 SOUL heme-binding protein DUF2358 PF10184.9 EWM28696.1 - 0.03 14.6 0.0 0.08 13.2 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2358) PhoLip_ATPase_C PF16212.5 EWM28697.1 - 5e-19 69.0 7.2 5.9e-19 68.8 7.2 1.1 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PP2C PF00481.21 EWM28699.1 - 1.7e-56 191.7 0.2 3.1e-56 190.9 0.2 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C FHA PF00498.26 EWM28699.1 - 2.3e-16 59.9 0.0 1.1e-12 48.1 0.0 3.1 3 0 0 3 3 3 2 FHA domain Yop-YscD_cpl PF16697.5 EWM28699.1 - 1.8e-10 41.0 0.0 6.4e-10 39.2 0.0 2.0 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain MT-A70 PF05063.14 EWM28700.1 - 3.6e-54 183.3 0.0 4.1e-54 183.1 0.0 1.0 1 0 0 1 1 1 1 MT-A70 Erythrovirus_X PF06795.11 EWM28701.1 - 0.13 12.6 0.0 0.4 11.0 0.0 1.7 2 0 0 2 2 2 0 Erythrovirus X protein Tab2_like PF06485.11 EWM28702.1 - 1.8e-78 263.8 0.0 2.2e-78 263.5 0.0 1.1 1 0 0 1 1 1 1 RNA-binding protein Tab2/Atab2 Syntaxin_2 PF14523.6 EWM28703.1 - 3.3e-06 27.4 9.9 4.5e-06 27.0 2.5 2.3 2 0 0 2 2 2 2 Syntaxin-like protein SNARE PF05739.19 EWM28703.1 - 3.7e-06 26.8 0.1 1e-05 25.4 0.1 1.7 1 0 0 1 1 1 1 SNARE domain Laminin_II PF06009.12 EWM28703.1 - 0.86 9.6 10.4 0.33 10.9 1.7 2.5 2 1 0 2 2 2 0 Laminin Domain II Syntaxin PF00804.25 EWM28703.1 - 1.6 8.4 16.2 1.2 8.8 3.7 2.7 2 1 1 3 3 3 0 Syntaxin Peptidase_S10 PF00450.22 EWM28705.1 - 7.6e-100 335.2 0.0 2.6e-99 333.5 0.0 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase DUF2920 PF11144.8 EWM28705.1 - 0.29 10.3 0.0 0.43 9.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Mito_carr PF00153.27 EWM28706.1 - 1e-10 41.4 2.7 2.5e-05 24.1 0.4 2.3 2 0 0 2 2 2 2 Mitochondrial carrier protein HMGL-like PF00682.19 EWM28707.1 - 4.7e-60 203.4 0.0 5.5e-60 203.2 0.0 1.0 1 0 0 1 1 1 1 HMGL-like Mito_carr PF00153.27 EWM28708.1 - 2.1e-41 139.7 7.5 1.7e-17 63.1 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Laminin_G_3 PF13385.6 EWM28710.1 - 0.00016 21.8 0.0 0.00035 20.7 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Nucleoporin_N PF08801.11 EWM28710.1 - 0.041 12.6 0.0 0.18 10.5 0.0 2.0 2 0 0 2 2 2 0 Nup133 N terminal like ANAPC4_WD40 PF12894.7 EWM28710.1 - 0.14 12.5 0.0 0.4 11.0 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain VPS13 PF16908.5 EWM28711.1 - 2.1e-36 125.9 0.0 2.5e-33 115.8 0.0 2.9 3 0 0 3 3 3 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 EWM28711.1 - 2.4e-36 125.1 0.0 6e-32 110.8 0.0 2.5 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 EWM28711.1 - 6.2e-32 111.0 0.0 7.1e-23 81.3 0.0 3.4 3 0 0 3 3 3 3 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 EWM28711.1 - 1e-27 96.5 0.1 2.3e-27 95.4 0.1 1.6 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13_mid_rpt PF16910.5 EWM28711.1 - 1.8e-09 37.4 0.0 0.00012 21.6 0.0 2.5 2 0 0 2 2 2 2 Repeating coiled region of VPS13 Pkinase PF00069.25 EWM28712.1 - 6.4e-45 153.6 0.0 1.2e-44 152.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM28712.1 - 4.6e-22 78.5 0.0 1e-21 77.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EWM28712.1 - 6.2e-05 21.9 0.0 0.00011 21.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EWM28712.1 - 7.6e-05 22.2 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EWM28712.1 - 0.00033 20.7 0.0 0.0071 16.3 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EWM28712.1 - 0.15 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family OTU PF02338.19 EWM28713.1 - 1.5e-06 28.7 0.0 2.6e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Ubiquitin_2 PF14560.6 EWM28713.1 - 0.00098 19.5 0.0 0.0018 18.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain UBA PF00627.31 EWM28713.1 - 0.002 18.0 0.4 0.0042 17.0 0.0 1.8 2 0 0 2 2 2 1 UBA/TS-N domain ubiquitin PF00240.23 EWM28713.1 - 0.022 14.5 0.2 0.1 12.4 0.2 2.0 1 1 0 1 1 1 0 Ubiquitin family Toxin_32 PF08120.11 EWM28713.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Tamulustoxin family UBA_4 PF14555.6 EWM28713.1 - 0.17 11.7 0.0 0.44 10.4 0.0 1.7 2 0 0 2 2 2 0 UBA-like domain Trypsin_2 PF13365.6 EWM28714.1 - 5e-26 92.4 1.5 1.8e-25 90.6 0.2 2.4 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 EWM28714.1 - 5.1e-09 36.3 0.0 1.9e-08 34.5 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EWM28714.1 - 3.8e-08 33.0 0.2 1.3e-06 28.1 0.1 2.6 2 0 0 2 2 2 1 PDZ domain Trypsin PF00089.26 EWM28714.1 - 1.5e-06 28.2 0.0 9.9e-06 25.5 0.0 2.1 2 0 0 2 2 2 1 Trypsin PDZ PF00595.24 EWM28714.1 - 0.027 14.8 0.0 0.19 12.1 0.0 2.3 2 0 0 2 2 2 0 PDZ domain DUF1840 PF08895.11 EWM28714.1 - 0.036 14.4 0.2 0.036 14.4 0.2 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF1840) Acyltransferase PF01553.21 EWM28715.1 - 3.7e-20 71.9 0.0 6.1e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 EWM28715.1 - 0.00013 22.0 0.0 0.00031 20.8 0.0 1.7 2 0 0 2 2 2 1 Acyltransferase C-terminus Ribosomal_L7Ae PF01248.26 EWM28716.1 - 8.4e-24 83.1 2.1 1.2e-23 82.7 2.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Polyketide_cyc PF03364.20 EWM28717.1 - 9.4e-07 29.1 0.1 1.8e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 EWM28717.1 - 0.00052 20.3 0.2 0.0011 19.3 0.2 1.5 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Methyltransf_PK PF05891.12 EWM28718.1 - 3.8e-58 196.6 0.0 8.3e-33 113.7 0.0 2.2 2 0 0 2 2 2 2 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 EWM28718.1 - 0.00011 22.8 0.0 0.082 13.6 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EWM28718.1 - 0.0011 19.6 0.0 0.19 12.4 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EWM28718.1 - 0.042 14.6 0.0 0.55 11.0 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain ParA PF10609.9 EWM28719.1 - 1.1e-73 247.7 0.4 2.9e-67 226.7 1.7 2.4 2 0 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase FeS_assembly_P PF01883.19 EWM28719.1 - 1.8e-19 69.7 1.0 6.6e-19 67.9 0.4 2.3 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein DUF971 PF06155.12 EWM28719.1 - 3.3e-14 53.3 0.0 6.8e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CbiA PF01656.23 EWM28719.1 - 1.4e-10 41.4 0.0 1.9e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EWM28719.1 - 1.5e-10 41.3 1.6 3.5e-09 36.8 0.0 2.5 3 0 0 3 3 3 1 AAA domain MipZ PF09140.11 EWM28719.1 - 1.9e-08 33.9 0.1 1.3e-06 27.9 0.0 2.2 2 0 0 2 2 2 1 ATPase MipZ Fer4_NifH PF00142.18 EWM28719.1 - 5.2e-05 22.8 0.0 0.0002 20.9 0.0 1.9 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 EWM28719.1 - 0.0012 18.3 0.0 0.0034 16.9 0.0 1.7 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ VirC1 PF07015.11 EWM28719.1 - 0.0061 15.9 0.1 0.02 14.2 0.1 1.8 2 0 0 2 2 2 1 VirC1 protein ArsA_ATPase PF02374.15 EWM28719.1 - 0.016 14.4 2.1 0.09 11.9 0.3 2.4 2 1 0 2 2 2 0 Anion-transporting ATPase SRP54 PF00448.22 EWM28719.1 - 0.13 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.17 EWM28720.1 - 3.8e-39 134.9 0.1 4.4e-39 134.7 0.1 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GDPD PF03009.17 EWM28722.1 - 8.1e-25 88.0 0.0 3.2e-20 73.0 0.0 2.1 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family PI-PLC-X PF00388.19 EWM28722.1 - 0.066 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain OrfB_Zn_ribbon PF07282.11 EWM28723.1 - 2.3e-09 37.0 1.1 3.9e-09 36.3 1.1 1.4 1 0 0 1 1 1 1 Putative transposase DNA-binding domain GRIM-19 PF06212.12 EWM28724.1 - 5.6e-31 107.2 0.1 6.4e-31 107.0 0.1 1.0 1 0 0 1 1 1 1 GRIM-19 protein TPR_14 PF13428.6 EWM28725.1 - 9.1e-30 100.8 24.6 8.7e-06 26.1 0.1 10.8 3 2 8 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.17 EWM28725.1 - 2.9e-29 98.8 24.7 0.00086 19.2 0.1 11.0 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_19 PF14559.6 EWM28725.1 - 9.1e-23 80.6 2.2 1e-06 29.2 0.0 6.5 4 1 3 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 EWM28725.1 - 6.9e-22 75.8 0.9 0.013 15.7 0.0 9.9 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 EWM28725.1 - 9.4e-22 77.4 19.2 3.8e-09 37.0 0.3 7.6 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 EWM28725.1 - 2.6e-21 74.4 3.3 0.1 13.1 0.0 9.3 8 1 1 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 EWM28725.1 - 4.3e-19 67.5 3.6 0.018 14.9 0.0 9.2 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_12 PF13424.6 EWM28725.1 - 5.6e-19 68.2 21.4 0.027 14.8 0.1 7.7 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_15 PF13429.6 EWM28725.1 - 8.2e-13 48.2 10.7 9.3e-05 21.8 1.6 4.0 1 1 2 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 EWM28725.1 - 1.4e-10 41.1 19.0 0.37 11.5 0.0 9.9 11 0 0 11 11 11 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EWM28725.1 - 1e-08 35.3 0.1 0.015 15.5 0.0 4.4 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 EWM28725.1 - 1.1e-06 28.6 0.9 6.6 6.9 0.0 7.1 9 0 0 9 9 9 2 MIT (microtubule interacting and transport) domain TPR_9 PF13371.6 EWM28725.1 - 4e-05 23.7 13.3 0.016 15.4 0.0 5.7 4 2 4 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 EWM28725.1 - 0.0004 20.2 14.4 55 4.1 0.0 8.6 9 1 1 10 10 9 0 Tetratricopeptide repeat NARP1 PF12569.8 EWM28725.1 - 0.00054 19.0 0.0 0.36 9.7 0.0 3.8 2 2 3 5 5 5 2 NMDA receptor-regulated protein 1 Mad3_BUB1_I PF08311.12 EWM28725.1 - 0.00062 19.7 6.6 14 5.7 0.1 6.0 6 1 1 7 7 7 0 Mad3/BUB1 homology region 1 FAT PF02259.23 EWM28725.1 - 0.0024 17.2 3.6 0.91 8.7 0.3 3.3 2 1 1 3 3 3 1 FAT domain TPR_11 PF13414.6 EWM28725.1 - 0.0064 16.1 2.1 37 4.1 0.0 5.8 4 2 1 5 5 5 0 TPR repeat HemY_N PF07219.13 EWM28725.1 - 0.047 13.9 1.5 4.4 7.6 0.0 3.5 3 0 0 3 3 3 0 HemY protein N-terminus Suf PF05843.14 EWM28725.1 - 0.048 13.7 0.7 12 5.8 0.1 3.4 2 2 1 3 3 3 0 Suppressor of forked protein (Suf) TPR_4 PF07721.14 EWM28725.1 - 0.064 13.9 12.7 2.7 8.9 0.1 5.3 5 1 1 6 6 3 0 Tetratricopeptide repeat PPR PF01535.20 EWM28725.1 - 0.14 12.5 5.7 9.4 6.7 0.0 5.8 6 0 0 6 6 6 0 PPR repeat TPR_10 PF13374.6 EWM28725.1 - 2.2 8.2 36.1 7.6 6.6 0.1 9.5 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_14 PF13428.6 EWM28726.1 - 3.9e-25 86.4 17.9 6.6e-06 26.5 0.1 8.9 3 1 6 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 EWM28726.1 - 1.3e-22 78.0 17.2 0.00066 19.6 0.1 9.2 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 EWM28726.1 - 1.3e-19 70.5 2.6 7.3e-07 29.6 0.0 5.6 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 EWM28726.1 - 3.8e-19 69.0 15.2 2.9e-09 37.4 0.3 6.7 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 EWM28726.1 - 8.6e-19 66.5 4.1 0.077 13.4 0.0 8.1 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 EWM28726.1 - 3.6e-18 64.2 0.8 0.0099 16.0 0.0 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 EWM28726.1 - 5.8e-15 55.4 13.3 0.02 15.2 0.1 5.8 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.28 EWM28726.1 - 1.3e-14 53.3 1.5 0.014 15.2 0.0 7.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_15 PF13429.6 EWM28726.1 - 8.5e-11 41.6 7.5 5e-05 22.7 4.0 3.8 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 EWM28726.1 - 1e-08 35.3 14.8 0.28 11.9 0.0 8.1 9 0 0 9 9 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EWM28726.1 - 1.6e-08 34.6 0.0 0.011 15.9 0.0 3.7 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EWM28726.1 - 4.3e-05 23.6 10.4 0.012 15.8 0.1 4.6 3 1 3 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 EWM28726.1 - 0.00019 21.2 9.1 45 4.4 0.0 7.3 7 1 1 8 8 8 0 Tetratricopeptide repeat MIT PF04212.18 EWM28726.1 - 0.0008 19.4 0.5 5.9 7.0 0.0 5.6 7 0 0 7 7 7 1 MIT (microtubule interacting and transport) domain NARP1 PF12569.8 EWM28726.1 - 0.00087 18.3 0.0 0.35 9.7 0.0 3.4 2 1 2 4 4 4 2 NMDA receptor-regulated protein 1 FAT PF02259.23 EWM28726.1 - 0.0031 16.8 4.1 1.3 8.1 2.3 3.2 2 1 0 2 2 2 1 FAT domain TPR_11 PF13414.6 EWM28726.1 - 0.0032 17.1 2.0 29 4.4 0.0 5.5 4 2 2 6 6 6 0 TPR repeat Mad3_BUB1_I PF08311.12 EWM28726.1 - 0.012 15.6 7.3 11 6.1 0.1 5.3 6 1 1 7 7 6 0 Mad3/BUB1 homology region 1 PPR PF01535.20 EWM28726.1 - 0.022 15.0 0.3 7.3 7.1 0.0 4.5 4 0 0 4 4 4 0 PPR repeat TPR_4 PF07721.14 EWM28726.1 - 0.59 10.9 11.7 2.1 9.2 0.1 4.5 4 1 1 5 5 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EWM28726.1 - 0.99 9.4 28.3 5.9 6.9 0.1 7.8 9 0 0 9 9 9 0 Tetratricopeptide repeat BTAD PF03704.17 EWM28726.1 - 4 7.9 11.2 0.93 9.9 0.1 4.0 3 2 0 4 4 3 0 Bacterial transcriptional activator domain Mito_carr PF00153.27 EWM28727.1 - 3e-13 49.5 7.7 0.0012 18.7 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Mpv17_PMP22 PF04117.12 EWM28728.1 - 4.4e-20 71.7 0.1 4.4e-20 71.7 0.1 2.0 3 0 0 3 3 3 1 Mpv17 / PMP22 family Gemini_AC4_5_2 PF08464.10 EWM28728.1 - 0.0073 16.2 0.8 2.2 8.3 0.1 2.5 2 0 0 2 2 2 2 Geminivirus AC4/5 conserved region DOT1 PF08123.13 EWM28729.1 - 1.4e-11 44.4 0.0 2e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_4 PF02390.17 EWM28729.1 - 0.0027 17.2 0.0 0.0039 16.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.20 EWM28729.1 - 0.01 15.1 0.0 0.013 14.8 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 EWM28729.1 - 0.041 14.5 0.0 0.064 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EWM28729.1 - 0.078 12.8 0.0 0.11 12.3 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 EWM28730.1 - 2.2e-11 43.7 0.0 3.6e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_4 PF02390.17 EWM28730.1 - 0.0038 16.7 0.0 0.0059 16.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.20 EWM28730.1 - 0.016 14.6 0.0 0.021 14.1 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 EWM28730.1 - 0.061 14.0 0.0 0.1 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EWM28730.1 - 0.12 12.1 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 EWM28731.1 - 2.2e-11 43.7 0.0 3.6e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_4 PF02390.17 EWM28731.1 - 0.0038 16.7 0.0 0.0059 16.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.20 EWM28731.1 - 0.016 14.6 0.0 0.021 14.1 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 EWM28731.1 - 0.061 14.0 0.0 0.1 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EWM28731.1 - 0.12 12.1 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 EWM28732.1 - 2.2e-11 43.7 0.0 3.6e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_4 PF02390.17 EWM28732.1 - 0.0038 16.7 0.0 0.0059 16.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.20 EWM28732.1 - 0.016 14.6 0.0 0.021 14.1 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 EWM28732.1 - 0.061 14.0 0.0 0.1 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EWM28732.1 - 0.12 12.1 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 EWM28733.1 - 1.3e-11 44.5 0.0 1.8e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_4 PF02390.17 EWM28733.1 - 0.0025 17.3 0.0 0.0037 16.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.20 EWM28733.1 - 0.0098 15.2 0.0 0.012 14.9 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 EWM28733.1 - 0.038 14.6 0.0 0.06 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EWM28733.1 - 0.072 12.9 0.0 0.1 12.4 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain SpoU_methylase PF00588.19 EWM28734.1 - 2.5e-09 37.4 0.0 4.4e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family GRIP PF01465.20 EWM28735.1 - 5.2e-13 48.7 0.0 1.4e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 GRIP domain Spc7 PF08317.11 EWM28735.1 - 0.00062 18.8 15.3 0.00062 18.8 15.3 7.3 4 2 2 6 6 6 4 Spc7 kinetochore protein Prefoldin_2 PF01920.20 EWM28735.1 - 0.0028 17.6 2.6 0.0028 17.6 2.6 11.4 9 3 1 11 11 11 3 Prefoldin subunit Surfac_D-trimer PF09006.11 EWM28735.1 - 0.46 10.4 7.3 18 5.3 0.1 5.3 5 0 0 5 5 5 0 Lung surfactant protein D coiled-coil trimerisation Golgin_A5 PF09787.9 EWM28735.1 - 9.2 5.6 111.3 0.02 14.4 14.7 6.4 4 2 2 6 6 6 0 Golgin subfamily A member 5 DUF1322 PF07032.11 EWM28736.1 - 0.07 13.7 0.0 0.96 10.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1322) PPR_2 PF13041.6 EWM28737.1 - 4e-50 167.8 0.0 2.5e-10 40.4 0.0 8.6 8 1 1 9 9 9 7 PPR repeat family PPR_1 PF12854.7 EWM28737.1 - 1.2e-34 117.7 0.6 0.016 14.9 0.0 11.2 11 0 0 11 11 11 9 PPR repeat PPR_3 PF13812.6 EWM28737.1 - 3.7e-32 110.2 0.0 8.4e-07 29.0 0.0 7.5 5 1 3 8 8 8 7 Pentatricopeptide repeat domain PPR PF01535.20 EWM28737.1 - 3.5e-27 92.7 19.8 0.00051 20.1 0.0 12.3 14 1 0 14 14 14 7 PPR repeat PPR_long PF17177.4 EWM28737.1 - 2.9e-12 46.4 4.4 2.7e-08 33.5 0.4 3.8 3 1 1 4 4 4 3 Pentacotripeptide-repeat region of PRORP DUF3368 PF11848.8 EWM28737.1 - 1 9.2 4.2 8 6.3 0.0 4.0 5 0 0 5 5 5 0 Domain of unknown function (DUF3368) B12-binding_2 PF02607.17 EWM28737.1 - 3.5 8.1 8.7 2.4 8.6 0.3 4.0 4 0 0 4 4 4 0 B12 binding domain Pkinase PF00069.25 EWM28738.1 - 3.5e-131 436.4 0.0 4.5e-65 219.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EWM28738.1 - 2.5e-70 236.7 0.0 1.7e-36 125.8 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EWM28738.1 - 1.1e-13 51.1 0.0 5.3e-06 25.9 0.0 3.6 4 0 0 4 4 4 2 Kinase-like APH PF01636.23 EWM28738.1 - 1.6e-06 28.2 4.3 0.0062 16.5 0.2 3.1 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 EWM28738.1 - 0.00016 21.1 0.0 0.23 10.8 0.0 2.6 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 EWM28738.1 - 0.00017 21.7 0.1 0.013 15.7 0.0 2.6 2 1 0 2 2 2 1 ABC1 family FTA2 PF13095.6 EWM28738.1 - 0.00018 21.2 0.3 0.84 9.2 0.0 3.0 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EWM28738.1 - 0.0009 18.1 0.0 0.35 9.6 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase Choline_kinase PF01633.20 EWM28738.1 - 0.022 14.3 0.0 3.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Choline/ethanolamine kinase YdjO PF14169.6 EWM28738.1 - 0.063 13.0 0.1 2 8.2 0.0 2.7 2 0 0 2 2 2 0 Cold-inducible protein YdjO Seadorna_VP7 PF07387.11 EWM28738.1 - 0.1 11.6 0.0 12 4.9 0.0 2.2 2 0 0 2 2 2 0 Seadornavirus VP7 Peptidase_S10 PF00450.22 EWM28739.1 - 1.2e-103 347.7 0.0 1.4e-102 344.3 0.0 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase DUF883 PF05957.13 EWM28740.1 - 1.4e-05 25.6 21.4 0.0053 17.3 1.1 4.7 1 1 4 6 6 6 3 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 EWM28740.1 - 6.9e-05 23.3 27.3 1.2 9.7 6.0 4.9 1 1 1 2 2 2 1 YtxH-like protein Apolipoprotein PF01442.18 EWM28740.1 - 0.023 14.6 15.5 0.019 14.9 9.7 2.5 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain LEA_4 PF02987.16 EWM28740.1 - 0.17 12.0 24.7 0.49 10.5 1.1 6.6 6 1 1 7 7 7 0 Late embryogenesis abundant protein ApoO PF09769.9 EWM28740.1 - 0.32 11.0 1.6 0.9 9.5 0.5 2.3 1 1 2 3 3 3 0 Apolipoprotein O RecG_N PF17190.4 EWM28740.1 - 0.45 11.3 2.7 0.54 11.0 0.7 2.1 2 1 0 2 2 2 0 RecG N-terminal helical domain MT0933_antitox PF14013.6 EWM28740.1 - 1.3 9.3 26.0 1.8 8.9 0.2 5.8 5 3 0 5 5 5 0 MT0933-like antitoxin protein DUF948 PF06103.11 EWM28740.1 - 2.9 8.2 6.5 1 9.7 1.6 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF3484 PF11983.8 EWM28740.1 - 3.4 8.8 0.0 3.4 8.8 0.0 3.9 3 1 0 3 3 3 0 Membrane-attachment and polymerisation-promoting switch Hamartin PF04388.12 EWM28740.1 - 3.5 6.2 7.8 4.3 5.9 7.8 1.1 1 0 0 1 1 1 0 Hamartin protein DUF883 PF05957.13 EWM28741.1 - 1.7e-06 28.5 21.7 0.005 17.4 1.0 4.7 1 1 5 6 6 6 5 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 EWM28741.1 - 0.00015 22.3 29.1 0.059 13.9 1.0 5.0 1 1 1 3 3 3 1 YtxH-like protein Apolipoprotein PF01442.18 EWM28741.1 - 0.001 19.0 16.5 0.014 15.3 9.5 2.5 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain LEA_4 PF02987.16 EWM28741.1 - 0.022 14.9 26.1 0.46 10.6 1.1 6.7 6 1 1 7 7 7 0 Late embryogenesis abundant protein RecG_N PF17190.4 EWM28741.1 - 0.45 11.3 2.8 0.5 11.1 0.7 2.2 2 1 0 2 2 2 0 RecG N-terminal helical domain MT0933_antitox PF14013.6 EWM28741.1 - 0.66 10.3 28.0 1.7 9.0 0.2 6.2 5 3 0 5 5 5 0 MT0933-like antitoxin protein ApoO PF09769.9 EWM28741.1 - 1.4 8.9 4.2 0.85 9.6 0.4 2.5 2 1 2 4 4 4 0 Apolipoprotein O DUF3484 PF11983.8 EWM28741.1 - 3.2 8.9 0.0 3.2 8.9 0.0 4.0 3 1 0 3 3 3 0 Membrane-attachment and polymerisation-promoting switch Hamartin PF04388.12 EWM28741.1 - 5.4 5.6 8.3 6.5 5.3 8.3 1.1 1 0 0 1 1 1 0 Hamartin protein ketoacyl-synt PF00109.26 EWM28742.1 - 3.6e-53 180.7 1.5 3.6e-53 180.7 1.5 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EWM28742.1 - 6.2e-35 119.8 2.0 1.4e-34 118.6 2.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EWM28742.1 - 0.00052 19.5 3.1 0.00066 19.1 0.6 2.2 3 0 0 3 3 3 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 EWM28742.1 - 0.0014 18.4 0.5 0.3 11.0 0.4 2.7 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Peptidase_M22 PF00814.25 EWM28743.1 - 8.8e-85 284.7 0.0 1.1e-84 284.4 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 EWM28743.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus UCR_14kD PF02271.16 EWM28744.1 - 2.8e-24 85.0 0.4 3.3e-24 84.7 0.4 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit MIF4G PF02854.19 EWM28745.1 - 2.4e-41 141.7 0.8 6.9e-28 97.7 0.6 2.3 2 0 0 2 2 2 2 MIF4G domain MA3 PF02847.17 EWM28745.1 - 9.4e-05 22.4 0.0 0.00023 21.1 0.0 1.7 1 0 0 1 1 1 1 MA3 domain Topo-VIb_trans PF09239.11 EWM28746.1 - 1.1e-54 184.5 0.0 2.9e-54 183.2 0.0 1.7 1 0 0 1 1 1 1 Topoisomerase VI B subunit, transducer HATPase_c_3 PF13589.6 EWM28746.1 - 1.2e-06 28.4 0.1 4e-05 23.5 0.0 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EWM28746.1 - 3.6e-06 27.5 0.0 2.5e-05 24.7 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Stimulus_sens_1 PF13756.6 EWM28746.1 - 0.053 14.1 0.2 8.2 7.1 0.0 2.6 1 1 1 2 2 2 0 Stimulus-sensing domain VPS13_C PF16909.5 EWM28747.1 - 2.9e-45 154.2 0.2 1.4e-40 139.0 0.2 3.2 2 1 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal C2 PF00168.30 EWM28747.1 - 6.5e-27 93.8 0.1 5.7e-20 71.5 0.1 2.7 2 0 0 2 2 2 2 C2 domain SHR-BD PF06650.12 EWM28747.1 - 6.5e-24 84.8 0.1 1.1e-13 51.2 0.0 4.3 4 0 0 4 4 4 3 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 EWM28747.1 - 1.4e-18 67.1 0.0 4e-18 65.6 0.0 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 EWM28747.1 - 4.9e-17 62.5 0.7 1.7e-16 60.7 0.2 2.3 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal PDZ_6 PF17820.1 EWM28747.1 - 0.0025 17.6 0.0 0.0056 16.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EWM28747.1 - 0.032 14.6 0.0 0.086 13.2 0.0 1.7 1 0 0 1 1 1 0 PDZ domain PDZ_2 PF13180.6 EWM28747.1 - 0.15 12.4 0.0 0.38 11.1 0.0 1.7 1 0 0 1 1 1 0 PDZ domain TPT PF03151.16 EWM28748.1 - 2.8e-11 43.3 11.6 3.8e-11 42.9 11.6 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 EWM28748.1 - 4.5e-07 29.4 12.5 7.1e-07 28.7 12.5 1.2 1 0 0 1 1 1 1 UAA transporter family DCB PF16213.5 EWM28749.1 - 0.00084 19.1 0.0 0.0047 16.6 0.0 2.0 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 PIF1 PF05970.14 EWM28750.1 - 1.4e-53 182.4 0.0 3.5e-38 131.7 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 EWM28750.1 - 1.8e-18 66.9 0.0 3.3e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EWM28750.1 - 5e-07 30.2 0.0 2.9e-06 27.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EWM28750.1 - 0.0024 18.1 0.0 0.012 15.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain SH3_13 PF18335.1 EWM28750.1 - 0.006 16.4 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain IstB_IS21 PF01695.17 EWM28750.1 - 0.007 16.1 0.1 1.3 8.7 0.0 2.4 1 1 1 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.6 EWM28750.1 - 0.01 16.2 0.1 0.068 13.6 0.1 2.2 1 1 0 1 1 1 0 AAA ATPase domain Herpes_Helicase PF02689.14 EWM28750.1 - 0.013 13.5 0.0 0.64 7.9 0.0 2.1 2 0 0 2 2 2 0 Helicase T2SSE PF00437.20 EWM28750.1 - 0.017 14.2 0.1 0.028 13.5 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Viral_helicase1 PF01443.18 EWM28750.1 - 0.022 14.5 0.0 0.29 10.8 0.1 2.6 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 EWM28750.1 - 0.04 13.7 0.0 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase NACHT PF05729.12 EWM28750.1 - 0.042 13.8 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain UvrD_C_2 PF13538.6 EWM28750.1 - 0.059 13.2 0.5 0.5 10.2 0.5 2.3 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA PF00004.29 EWM28750.1 - 0.075 13.5 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EWM28750.1 - 0.15 11.5 0.5 1 8.7 0.0 2.2 1 1 1 2 2 2 0 PhoH-like protein TsaE PF02367.17 EWM28750.1 - 0.15 12.1 0.3 0.62 10.1 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF1077 PF06417.12 EWM28752.1 - 4.7e-35 120.1 0.9 6.3e-35 119.7 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) PAS_7 PF12860.7 EWM28752.1 - 0.12 12.5 0.3 3.3 7.9 0.0 2.1 2 0 0 2 2 2 0 PAS fold tRNA-synt_1d PF00750.19 EWM28753.1 - 3.3e-117 391.3 0.0 4.6e-117 390.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EWM28753.1 - 9.6e-21 74.2 1.9 1.4e-19 70.5 0.2 2.4 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 EWM28753.1 - 4.9e-14 52.7 0.0 1.1e-13 51.5 0.0 1.7 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.19 EWM28753.1 - 0.0029 17.0 0.0 0.0045 16.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EWM28753.1 - 0.062 12.0 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EWM28753.1 - 0.11 10.8 0.0 0.17 10.1 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) WD40 PF00400.32 EWM28754.1 - 1.6e-27 95.2 25.7 3.6e-07 30.8 0.2 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat DNA_photolyase PF00875.18 EWM28754.1 - 3.7e-15 56.3 0.2 8.7e-15 55.1 0.2 1.6 1 0 0 1 1 1 1 DNA photolyase ANAPC4_WD40 PF12894.7 EWM28754.1 - 1.9e-09 37.7 0.1 0.069 13.5 0.1 4.4 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain FAD_binding_7 PF03441.14 EWM28754.1 - 0.0011 18.5 0.3 0.0017 17.8 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase CBFB_NFYA PF02045.15 EWM28755.1 - 5.9e-26 90.9 5.5 1.2e-25 89.9 5.5 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B adh_short_C2 PF13561.6 EWM28756.1 - 7.7e-51 172.9 2.6 1.1e-50 172.4 2.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EWM28756.1 - 1.5e-41 142.0 0.5 1.9e-41 141.7 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EWM28756.1 - 8.8e-10 38.8 1.1 1.7e-09 37.8 1.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EWM28756.1 - 0.0057 16.1 0.4 0.01 15.3 0.4 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family SEF14_adhesin PF06443.11 EWM28756.1 - 0.016 15.1 0.8 0.034 14.0 0.6 1.7 1 1 0 1 1 1 0 SEF14-like adhesin Polysacc_synt_2 PF02719.15 EWM28756.1 - 0.041 13.0 0.1 0.056 12.6 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.6 EWM28756.1 - 0.094 13.4 0.1 0.19 12.4 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain DAGK_cat PF00781.24 EWM28757.1 - 5.1e-25 87.5 0.0 9.5e-25 86.7 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Cofilin_ADF PF00241.20 EWM28758.1 - 9.2e-19 67.4 0.0 2e-08 34.0 0.0 2.3 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein M20_dimer PF07687.14 EWM28759.1 - 8e-20 70.8 0.0 1.2e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 EWM28759.1 - 0.00012 21.9 0.1 0.00037 20.2 0.1 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 zf-C2H2 PF00096.26 EWM28760.1 - 0.0003 21.1 5.8 0.072 13.6 0.9 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EWM28760.1 - 0.43 11.5 8.4 8.4 7.5 1.9 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EWM28760.1 - 0.67 10.5 8.1 0.34 11.4 0.4 3.1 3 0 0 3 3 3 0 Zinc-finger double domain Inositol_P PF00459.25 EWM28761.1 - 2.8e-48 164.8 0.2 8.3e-48 163.2 0.2 1.6 1 1 0 1 1 1 1 Inositol monophosphatase family Dysbindin PF04440.16 EWM28762.1 - 0.06 13.5 0.1 14 5.8 0.0 2.6 2 0 0 2 2 2 0 Dysbindin (Dystrobrevin binding protein 1) PPR PF01535.20 EWM28763.1 - 1.4e-19 68.9 1.2 1.3e-05 25.1 0.0 4.8 5 0 0 5 5 5 4 PPR repeat PPR_2 PF13041.6 EWM28763.1 - 4.5e-18 65.2 0.0 3.5e-06 27.1 0.0 4.0 2 1 2 4 4 4 3 PPR repeat family PPR_1 PF12854.7 EWM28763.1 - 6.1e-17 61.0 0.1 0.00019 21.1 0.0 4.5 4 0 0 4 4 4 4 PPR repeat PPR_3 PF13812.6 EWM28763.1 - 4.1e-05 23.6 0.0 0.16 12.1 0.0 3.1 2 1 1 3 3 3 3 Pentatricopeptide repeat domain PPR_long PF17177.4 EWM28763.1 - 0.021 14.2 0.0 4.4 6.6 0.0 2.2 1 1 1 2 2 2 0 Pentacotripeptide-repeat region of PRORP TPR_1 PF00515.28 EWM28765.1 - 3.7e-15 55.0 13.4 1.1e-05 25.0 0.5 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EWM28765.1 - 5.1e-12 44.9 13.0 6.9e-05 22.7 0.9 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EWM28765.1 - 1.2e-06 28.2 5.7 0.001 19.1 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EWM28765.1 - 2.7e-06 27.9 7.0 0.0013 19.4 3.9 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EWM28765.1 - 1.6e-05 24.5 7.5 0.0096 15.6 0.7 3.3 2 1 1 3 3 3 3 TPR repeat TPR_14 PF13428.6 EWM28765.1 - 0.00016 22.2 6.3 0.0074 17.0 1.6 3.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EWM28765.1 - 0.00092 19.3 1.9 0.0028 17.8 1.9 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat BTAD PF03704.17 EWM28765.1 - 0.0012 19.3 4.2 0.067 13.6 0.4 3.2 1 1 1 2 2 2 1 Bacterial transcriptional activator domain TPR_17 PF13431.6 EWM28765.1 - 0.021 15.2 7.3 0.043 14.2 0.8 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3856 PF12968.7 EWM28765.1 - 0.077 13.1 0.3 3.3 7.8 0.1 3.5 2 1 1 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_10 PF13374.6 EWM28765.1 - 0.13 12.1 3.7 8.8 6.3 0.1 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EWM28765.1 - 0.22 12.0 7.6 0.19 12.3 1.9 3.3 1 1 2 3 3 3 0 Tetratricopeptide repeat Arm PF00514.23 EWM28765.1 - 0.31 11.2 2.5 96 3.2 0.0 4.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat TPR_12 PF13424.6 EWM28765.1 - 0.47 10.8 18.1 0.035 14.4 3.4 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EWM28765.1 - 0.84 10.4 9.4 0.92 10.3 0.9 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF525 PF04379.14 EWM28767.1 - 1.9e-09 37.6 0.0 4.4e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 ApaG domain GAIN_A PF18619.1 EWM28767.1 - 0.015 15.4 0.1 11 6.3 0.0 2.8 2 0 0 2 2 2 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A Zip PF02535.22 EWM28768.1 - 5e-39 134.4 29.8 1.7e-26 93.2 16.7 2.3 1 1 1 2 2 2 2 ZIP Zinc transporter DUF4342 PF14242.6 EWM28768.1 - 4.7 7.3 5.5 18 5.4 5.5 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) V-SNARE PF05008.15 EWM28769.1 - 6.8e-10 39.2 0.1 6.8e-10 39.2 0.1 2.2 3 1 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 EWM28769.1 - 1.8e-09 37.8 3.6 1.8e-09 37.8 3.6 2.1 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EWM28769.1 - 0.00029 20.7 0.8 0.0018 18.1 0.1 2.5 2 2 1 3 3 3 1 Sec20 SOGA PF11365.8 EWM28769.1 - 0.0076 17.3 1.9 2 9.6 0.1 2.6 2 0 0 2 2 2 1 Protein SOGA Halo_GVPC PF05465.13 EWM28769.1 - 0.017 15.4 0.5 0.038 14.3 0.5 1.6 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat Med8 PF10232.9 EWM28769.1 - 0.026 14.1 1.6 0.058 13.0 0.1 1.8 1 1 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 Laminin_II PF06009.12 EWM28769.1 - 0.1 12.6 4.1 0.46 10.5 1.4 2.2 2 0 0 2 2 2 0 Laminin Domain II SlyX PF04102.12 EWM28769.1 - 0.14 12.8 0.6 0.14 12.8 0.6 3.2 3 1 0 3 3 3 0 SlyX DUF641 PF04859.12 EWM28769.1 - 0.14 12.4 3.9 6 7.2 0.5 2.5 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF948 PF06103.11 EWM28769.1 - 0.34 11.2 1.4 15 5.9 0.1 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) KxDL PF10241.9 EWM28769.1 - 0.43 10.9 2.6 3.8 7.9 0.4 3.0 2 1 1 3 3 3 0 Uncharacterized conserved protein DUF1664 PF07889.12 EWM28769.1 - 0.61 10.1 4.6 4.8 7.2 1.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) XhlA PF10779.9 EWM28769.1 - 0.73 10.1 3.0 2.1 8.6 1.1 2.5 2 0 0 2 2 2 0 Haemolysin XhlA LURAP PF14854.6 EWM28769.1 - 1 9.3 3.7 1.6 8.7 1.0 2.1 2 0 0 2 2 2 0 Leucine rich adaptor protein V-SNARE PF05008.15 EWM28770.1 - 5.4e-10 39.5 0.1 5.4e-10 39.5 0.1 2.1 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 EWM28770.1 - 8.5e-07 29.2 1.8 8.5e-07 29.2 1.8 2.2 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Vps53_N PF04100.12 EWM28770.1 - 0.012 14.6 3.3 1.4 7.8 1.8 2.2 2 0 0 2 2 2 0 Vps53-like, N-terminal Halo_GVPC PF05465.13 EWM28770.1 - 0.014 15.6 0.5 0.033 14.4 0.5 1.7 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat SOGA PF11365.8 EWM28770.1 - 0.019 16.1 2.6 1.7 9.8 0.1 2.6 2 0 0 2 2 2 0 Protein SOGA Med8 PF10232.9 EWM28770.1 - 0.025 14.2 2.8 0.13 11.9 2.8 2.0 1 1 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 SlyX PF04102.12 EWM28770.1 - 0.058 14.0 1.3 0.058 14.0 1.3 3.2 3 1 0 3 3 3 0 SlyX Laminin_II PF06009.12 EWM28770.1 - 0.15 12.1 1.7 2 8.4 0.3 2.3 2 0 0 2 2 2 0 Laminin Domain II Tropomyosin PF00261.20 EWM28770.1 - 0.19 11.1 7.5 1.4 8.2 0.6 2.3 2 0 0 2 2 2 0 Tropomyosin DUF641 PF04859.12 EWM28770.1 - 0.22 11.8 4.8 7.3 6.9 0.8 2.5 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) Spc7 PF08317.11 EWM28770.1 - 0.91 8.3 4.8 1.1 8.1 3.9 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein XhlA PF10779.9 EWM28770.1 - 1 9.6 3.4 2.1 8.6 1.2 2.3 2 0 0 2 2 2 0 Haemolysin XhlA MPP6 PF10175.9 EWM28771.1 - 2.4e-12 47.5 12.5 4.9e-12 46.5 12.5 1.4 1 1 0 1 1 1 1 M-phase phosphoprotein 6 DUF2802 PF10975.8 EWM28772.1 - 0.16 12.1 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) Ly49 PF08391.10 EWM28772.1 - 0.26 11.7 0.4 1.4 9.3 0.8 1.9 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region polyprenyl_synt PF00348.17 EWM28774.1 - 7.9e-60 202.1 0.0 1e-59 201.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Myf5 PF12232.8 EWM28774.1 - 8.8 7.2 8.4 20 6.0 7.8 1.9 1 1 0 1 1 1 0 Myogenic determination factor 5 polyprenyl_synt PF00348.17 EWM28775.1 - 4.9e-60 202.7 0.0 6.3e-60 202.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase BolA PF01722.18 EWM28777.1 - 1.2e-13 51.1 0.0 2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 BolA-like protein PLU-1 PF08429.11 EWM28778.1 - 4.2e-63 213.6 37.3 3.3e-27 95.6 0.5 7.3 5 1 2 7 7 7 7 PLU-1-like protein PHD PF00628.29 EWM28778.1 - 1.5e-13 50.4 28.2 2.9e-07 30.3 7.6 2.6 2 0 0 2 2 2 2 PHD-finger ELM2 PF01448.24 EWM28778.1 - 0.00016 22.4 0.0 0.00058 20.6 0.0 2.1 1 0 0 1 1 1 1 ELM2 domain Med9 PF07544.13 EWM28778.1 - 0.13 12.4 1.2 1.4 9.0 0.0 3.5 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF948 PF06103.11 EWM28778.1 - 0.16 12.2 2.5 14 6.0 0.1 4.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) FlgT_N PF16548.5 EWM28778.1 - 0.19 12.3 1.8 6 7.5 0.2 2.8 2 0 0 2 2 2 0 Flagellar assembly protein T, N-terminal domain C1_1 PF00130.22 EWM28778.1 - 0.99 9.3 28.9 0.0077 16.1 4.8 3.7 3 1 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 EWM28778.1 - 1.7 8.3 15.1 0.19 11.3 3.7 2.6 2 0 0 2 2 2 0 PHD-finger DUF4704 PF15787.5 EWM28779.1 - 0.24 10.6 0.0 0.32 10.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4704) GidB PF02527.15 EWM28780.1 - 4.8e-32 110.8 0.0 6.9e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.6 EWM28780.1 - 2.4e-05 24.2 0.0 3.6e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EWM28780.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain FUN14 PF04930.15 EWM28781.1 - 4.5e-12 46.2 0.0 1.2e-11 44.8 0.0 1.7 2 0 0 2 2 2 1 FUN14 family tRNA_m1G_MT PF01746.21 EWM28782.1 - 8.4e-27 94.1 0.3 1.2e-26 93.6 0.0 1.4 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase TruB_N PF01509.18 EWM28783.1 - 9.8e-46 155.8 0.0 1.3e-45 155.4 0.0 1.2 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EWM28783.1 - 0.00035 20.7 0.0 0.0008 19.5 0.0 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain HECT PF00632.25 EWM28785.1 - 2.6e-77 260.4 0.0 3.2e-77 260.0 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DnaJ_C PF01556.18 EWM28785.1 - 0.076 13.1 0.0 3.7 7.6 0.0 3.0 2 1 2 4 4 4 0 DnaJ C terminal domain DAD PF02109.16 EWM28787.1 - 2.8e-35 120.9 5.4 3.2e-35 120.7 5.4 1.1 1 0 0 1 1 1 1 DAD family Vps36-NZF-N PF16988.5 EWM28788.1 - 0.25 10.7 9.2 0.79 9.2 0.3 3.0 2 1 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 EWM28788.1 - 0.34 11.0 10.4 0.47 10.5 0.9 3.6 1 1 2 3 3 3 0 Sec23/Sec24 zinc finger RecR PF02132.15 EWM28788.1 - 0.64 9.6 6.3 1.2 8.8 0.1 3.0 2 1 1 3 3 3 0 RecR protein Cript PF10235.9 EWM28788.1 - 0.98 10.0 6.3 8.8 7.0 6.3 2.3 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT zf-RanBP PF00641.18 EWM28788.1 - 7.2 6.0 12.9 1.4 8.3 1.1 3.3 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others V-SNARE_C PF12352.8 EWM28789.1 - 1e-07 32.1 1.9 1e-07 32.1 1.9 1.8 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 EWM28789.1 - 1.8e-06 28.2 0.2 1.8e-06 28.2 0.2 2.4 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Synaptobrevin PF00957.21 EWM28789.1 - 4.2e-05 23.2 1.1 4.2e-05 23.2 1.1 1.9 1 1 0 2 2 2 1 Synaptobrevin Sec20 PF03908.13 EWM28789.1 - 0.011 15.7 0.5 0.035 14.0 0.2 1.9 1 1 0 1 1 1 0 Sec20 HpaB_N PF11794.8 EWM28789.1 - 0.021 14.5 0.7 0.028 14.1 0.7 1.2 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Laminin_II PF06009.12 EWM28789.1 - 0.064 13.3 3.6 0.12 12.3 1.7 2.0 1 1 1 2 2 2 0 Laminin Domain II ATP-grasp_4 PF13535.6 EWM28790.1 - 7.5e-08 32.1 0.0 2.1e-07 30.6 0.0 1.8 2 1 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EWM28790.1 - 4.3e-06 26.9 0.0 7.8e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 EWM28790.1 - 1.2e-05 25.2 0.0 1.9e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_Ter PF15632.6 EWM28790.1 - 0.00013 21.8 0.0 0.028 14.2 0.0 2.9 3 1 0 3 3 3 1 ATP-grasp in the biosynthetic pathway with Ter operon LAL_C2 PF18603.1 EWM28790.1 - 0.00069 19.7 0.0 0.0019 18.3 0.0 1.7 2 0 0 2 2 2 1 L-amino acid ligase C-terminal domain 2 ATP-grasp_4 PF13535.6 EWM28791.1 - 7.5e-08 32.1 0.0 2.1e-07 30.6 0.0 1.8 2 1 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EWM28791.1 - 4.3e-06 26.9 0.0 7.8e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 EWM28791.1 - 1.2e-05 25.2 0.0 1.9e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_Ter PF15632.6 EWM28791.1 - 0.00013 21.8 0.0 0.028 14.2 0.0 2.9 3 1 0 3 3 3 1 ATP-grasp in the biosynthetic pathway with Ter operon LAL_C2 PF18603.1 EWM28791.1 - 0.00069 19.7 0.0 0.0019 18.3 0.0 1.7 2 0 0 2 2 2 1 L-amino acid ligase C-terminal domain 2 Mob_synth_C PF06463.13 EWM28792.1 - 1.1e-33 115.9 0.0 2.2e-33 114.9 0.0 1.5 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 EWM28792.1 - 6e-27 95.1 0.0 9.4e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EWM28792.1 - 8.2e-07 29.4 0.0 1.4e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EWM28792.1 - 0.0032 17.6 0.0 0.0058 16.8 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain VHS PF00790.19 EWM28793.1 - 5.9e-24 84.5 0.0 8.9e-24 83.9 0.0 1.3 1 0 0 1 1 1 1 VHS domain ADK PF00406.22 EWM28794.1 - 3.7e-46 157.0 0.0 4.4e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EWM28794.1 - 3.1e-19 69.8 0.0 6.9e-19 68.6 0.0 1.5 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 EWM28794.1 - 1.4e-14 53.8 0.0 2.1e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 EWM28794.1 - 0.00017 22.1 0.0 0.00052 20.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EWM28794.1 - 0.00059 20.0 0.2 0.0063 16.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 EWM28794.1 - 0.0098 15.6 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase AAA PF00004.29 EWM28794.1 - 0.15 12.5 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HIT PF01230.23 EWM28795.1 - 6.2e-19 68.6 0.0 1.1e-18 67.7 0.0 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EWM28795.1 - 8.2e-11 42.4 0.0 1.5e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EWM28795.1 - 0.048 13.5 0.0 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 PX PF00787.24 EWM28796.1 - 1.8e-12 47.3 1.3 2.6e-12 46.7 1.3 1.3 1 0 0 1 1 1 1 PX domain Erg28 PF03694.13 EWM28797.1 - 2.3e-27 95.6 5.6 2.3e-27 95.6 5.6 1.5 2 0 0 2 2 2 1 Erg28 like protein DUF1467 PF07330.12 EWM28797.1 - 3.2 7.8 8.5 11 6.0 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1467) E1-E2_ATPase PF00122.20 EWM28798.1 - 5.6e-06 26.0 0.0 5e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 E1-E2 ATPase DUF1279 PF06916.13 EWM28799.1 - 9.1e-14 51.8 1.1 2.8e-13 50.2 1.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) HSP20 PF00011.21 EWM28800.1 - 1e-23 83.4 2.0 1.3e-23 83.1 2.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EWM28800.1 - 8.2e-13 47.7 0.2 1.5e-12 46.9 0.2 1.5 1 1 0 1 1 1 1 HSP20-like domain found in ArsA DUF4097 PF13349.6 EWM28800.1 - 0.018 14.4 0.3 0.023 14.1 0.3 1.1 1 0 0 1 1 1 0 Putative adhesin DUF2807 PF10988.8 EWM28800.1 - 0.082 12.7 0.9 1.1 9.1 0.3 2.0 1 1 1 2 2 2 0 Putative auto-transporter adhesin, head GIN domain Aldose_epim PF01263.20 EWM28801.1 - 1.2e-26 93.7 0.1 2e-26 93.0 0.1 1.4 1 1 0 1 1 1 1 Aldose 1-epimerase DUF3943 PF13084.6 EWM28801.1 - 0.14 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3943) ABC1 PF03109.16 EWM28802.1 - 2.4e-17 63.2 0.0 1e-13 51.5 0.0 2.6 2 0 0 2 2 2 2 ABC1 family Pkinase PF00069.25 EWM28802.1 - 1.1e-05 24.9 0.0 8.3e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain RIO1 PF01163.22 EWM28802.1 - 4.3e-05 23.2 0.0 9.9e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EWM28802.1 - 0.0018 18.3 0.1 0.0099 15.8 0.0 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EWM28802.1 - 0.0071 15.7 0.0 0.13 11.5 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EWM28803.1 - 3.6e-65 220.0 0.0 4.6e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM28803.1 - 3.3e-31 108.5 0.0 4.3e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EWM28803.1 - 7.1e-06 25.7 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EWM28803.1 - 5.3e-05 22.7 0.1 9e-05 21.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EWM28803.1 - 0.0016 17.8 0.0 0.0047 16.3 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EWM28803.1 - 0.0038 16.0 0.0 0.015 14.1 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EWM28803.1 - 0.042 13.7 0.1 0.57 10.1 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family GST_N PF02798.20 EWM28805.1 - 4.7e-12 46.1 0.0 7.9e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EWM28805.1 - 1.8e-07 31.0 0.1 1.7e-06 27.9 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EWM28805.1 - 1e-06 29.1 0.0 2e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EWM28805.1 - 2e-05 24.8 0.0 3.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EWM28805.1 - 3.9e-05 23.8 0.0 6.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EWM28805.1 - 0.00033 20.8 0.0 0.00062 19.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SPT_ssu-like PF11779.8 EWM28806.1 - 2.6e-10 39.7 3.1 3.6e-10 39.3 3.1 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like dCMP_cyt_deam_1 PF00383.23 EWM28807.1 - 1.1e-18 66.9 0.0 1.8e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EWM28807.1 - 2.6e-07 30.5 0.0 4.1e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase Inv-AAD PF18785.1 EWM28807.1 - 7.2e-05 22.7 0.0 0.00024 21.0 0.0 1.8 1 1 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase Nitro_FeMo-Co PF02579.17 EWM28807.1 - 0.027 14.8 0.4 0.68 10.3 0.1 2.6 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor V4R PF02830.18 EWM28807.1 - 0.079 13.0 0.2 2 8.5 0.0 2.9 3 0 0 3 3 3 0 V4R domain APOBEC_N PF08210.11 EWM28807.1 - 0.19 11.6 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 APOBEC-like N-terminal domain DEAD PF00270.29 EWM28808.1 - 5.8e-13 49.0 0.0 5.9e-12 45.7 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.15 EWM28808.1 - 3.8e-12 46.6 0.0 4e-10 40.0 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 EWM28808.1 - 0.071 12.2 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 EWM28808.1 - 0.076 13.3 1.5 15 5.8 0.0 4.0 5 0 0 5 5 5 0 AAA domain DUF1749 PF08538.10 EWM28809.1 - 6.1e-34 117.5 0.0 7.5e-34 117.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Hydrolase_4 PF12146.8 EWM28809.1 - 0.083 12.1 0.0 6.7 5.9 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 NYN_YacP PF05991.11 EWM28811.1 - 8.9e-26 90.8 0.2 8.9e-26 90.8 0.2 1.8 2 0 0 2 2 2 1 YacP-like NYN domain DUF1378 PF07125.11 EWM28811.1 - 0.085 13.0 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) Methyltransf_4 PF02390.17 EWM28812.1 - 1.5e-35 122.2 0.0 2e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.6 EWM28812.1 - 0.0035 17.1 0.0 0.0063 16.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EWM28812.1 - 0.059 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EWM28812.1 - 0.066 13.0 0.0 0.28 11.0 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EWM28812.1 - 0.091 13.5 0.0 0.17 12.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EWM28812.1 - 0.096 12.2 0.0 0.29 10.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain Mei5_like PF17021.5 EWM28812.1 - 0.24 11.5 0.9 0.7 9.9 0.7 1.9 2 0 0 2 2 2 0 Putative double-strand recombination repair-like DNase_NucA_NucB PF14040.6 EWM28813.1 - 0.1 13.0 0.1 0.19 12.1 0.1 1.4 1 0 0 1 1 1 0 Deoxyribonuclease NucA/NucB DUF5337 PF17272.2 EWM28813.1 - 0.25 11.2 0.8 0.44 10.4 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5337) DNase_NucA_NucB PF14040.6 EWM28814.1 - 0.1 13.0 0.1 0.19 12.1 0.1 1.4 1 0 0 1 1 1 0 Deoxyribonuclease NucA/NucB DUF5337 PF17272.2 EWM28814.1 - 0.15 11.9 0.3 0.35 10.7 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5337) DUF1664 PF07889.12 EWM28815.1 - 0.0061 16.6 6.0 0.0061 16.6 6.0 3.8 2 1 0 3 3 3 2 Protein of unknown function (DUF1664) Bacillus_HBL PF05791.11 EWM28815.1 - 8.5 6.2 12.7 0.54 10.1 1.7 3.1 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DNA_pol_A_exo1 PF01612.20 EWM28817.1 - 2e-40 138.3 0.2 3.6e-40 137.5 0.2 1.4 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 EWM28817.1 - 5.7e-13 48.6 0.0 1e-11 44.7 0.0 2.6 2 0 0 2 2 2 1 HRDC domain PMC2NT PF08066.12 EWM28817.1 - 1.6e-07 31.9 0.1 5.1e-07 30.3 0.1 1.9 1 0 0 1 1 1 1 PMC2NT (NUC016) domain Bromo_TP PF07524.13 EWM28818.1 - 1.7e-10 40.8 0.1 2.5e-10 40.2 0.1 1.2 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.9 EWM28818.1 - 4.5e-09 36.7 0.4 4.5e-09 36.7 0.4 2.3 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term TFIID-31kDa PF02291.15 EWM28818.1 - 0.15 12.2 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Apolipoprotein PF01442.18 EWM28819.1 - 3.6e-05 23.7 0.4 0.00044 20.2 0.1 2.0 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain PRA1 PF03208.19 EWM28820.1 - 9.5e-25 86.9 0.2 1.5e-24 86.2 0.2 1.2 1 0 0 1 1 1 1 PRA1 family protein DUF2207 PF09972.9 EWM28820.1 - 0.34 9.6 2.3 0.61 8.8 2.3 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Neurensin PF14927.6 EWM28820.1 - 1.4 8.6 3.4 3.2 7.4 3.4 1.6 1 1 0 1 1 1 0 Neurensin CAP_GLY PF01302.25 EWM28822.1 - 3.1e-21 75.2 0.6 4.9e-21 74.5 0.6 1.3 1 0 0 1 1 1 1 CAP-Gly domain QWRF PF04484.12 EWM28822.1 - 4.6 6.9 16.1 1.8 8.2 8.5 2.1 2 0 0 2 2 2 0 QWRF family RNA_pol_Rpb1_5 PF04998.17 EWM28823.1 - 2.2e-85 286.3 0.0 3e-85 285.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_3 PF04983.18 EWM28823.1 - 1.1e-31 109.9 0.0 1.8e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EWM28823.1 - 4.8e-20 71.5 0.0 1.4e-19 70.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_2 PF00623.20 EWM28823.1 - 3.2e-18 66.5 0.1 5.9e-18 65.6 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 Comm PF15957.5 EWM28824.1 - 0.02 15.3 0.3 2.6 8.4 0.1 2.9 2 0 0 2 2 2 0 Commissureless Herpes_UL14 PF03580.14 EWM28824.1 - 0.083 13.1 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus UL14-like protein DUF4064 PF13273.6 EWM28824.1 - 0.18 12.1 0.0 0.18 12.1 0.0 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF4064) DUF1974 PF09317.11 EWM28825.1 - 7.4e-60 202.9 0.2 2.6e-59 201.1 0.2 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1974) Acyl-CoA_dh_N PF02771.16 EWM28825.1 - 6.9e-18 65.3 0.0 2.9e-17 63.3 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 EWM28825.1 - 8.2e-14 52.1 1.3 2e-13 50.8 1.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EWM28825.1 - 3.5e-08 33.5 0.0 8e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DUF1974 PF09317.11 EWM28826.1 - 7.4e-60 202.9 0.2 2.6e-59 201.1 0.2 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1974) Acyl-CoA_dh_N PF02771.16 EWM28826.1 - 6.9e-18 65.3 0.0 2.9e-17 63.3 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 EWM28826.1 - 8.2e-14 52.1 1.3 2e-13 50.8 1.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EWM28826.1 - 3.5e-08 33.5 0.0 8e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Chorein_N PF12624.7 EWM28827.1 - 2.7e-09 37.1 0.0 8.4e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 DUF1786 PF08735.10 EWM28827.1 - 0.022 14.0 0.0 0.06 12.6 0.0 1.6 2 0 0 2 2 2 0 Putative pyruvate format-lyase activating enzyme (DUF1786) Aminotran_3 PF00202.21 EWM28828.1 - 4.1e-94 315.5 0.0 4.8e-94 315.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III UPF0669 PF17065.5 EWM28829.1 - 1.6e-15 57.4 0.0 0.0015 18.3 0.0 7.9 8 0 0 8 8 8 6 Putative cytokine, C6ORF120 fn3 PF00041.21 EWM28829.1 - 0.1 13.0 0.1 0.59 10.5 0.0 2.3 2 0 0 2 2 2 0 Fibronectin type III domain RmlD_sub_bind PF04321.17 EWM28830.1 - 1.2e-17 64.0 0.0 5.5e-17 61.8 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EWM28830.1 - 1.3e-14 54.3 0.0 2.2e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EWM28830.1 - 2.7e-05 23.7 0.3 0.012 15.0 0.0 2.6 2 1 1 3 3 3 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EWM28830.1 - 3.5e-05 22.9 0.1 0.00013 21.1 0.1 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EWM28830.1 - 4.1e-05 22.9 0.0 7.9e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EWM28830.1 - 0.038 13.2 0.0 0.079 12.1 0.0 1.6 1 1 0 1 1 1 0 Male sterility protein PP2C PF00481.21 EWM28831.1 - 7.9e-67 225.6 0.0 1e-66 225.3 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EWM28831.1 - 5.4e-06 26.2 0.2 9e-06 25.5 0.2 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 EWM28832.1 - 7.9e-67 225.6 0.0 1e-66 225.3 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EWM28832.1 - 5.4e-06 26.2 0.2 9e-06 25.5 0.2 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Redoxin PF08534.10 EWM28833.1 - 2.4e-28 98.7 0.0 2.9e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EWM28833.1 - 2.6e-09 37.0 0.0 3.2e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family MMR_HSR1_Xtn PF16897.5 EWM28834.1 - 9.5e-33 112.4 0.1 1.6e-32 111.6 0.1 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EWM28834.1 - 1.2e-21 76.9 0.0 3.1e-21 75.6 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EWM28834.1 - 3e-10 39.9 0.0 5.9e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EWM28834.1 - 1.6e-06 28.2 0.0 0.017 15.1 0.0 2.4 2 0 0 2 2 2 2 Dynamin family AIG1 PF04548.16 EWM28834.1 - 0.0013 18.1 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 AIG1 family AAA_16 PF13191.6 EWM28834.1 - 0.019 15.3 0.0 0.037 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 EWM28834.1 - 0.069 13.1 0.1 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase SRPRB PF09439.10 EWM28834.1 - 0.11 11.9 0.1 0.26 10.7 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Roc PF08477.13 EWM28834.1 - 0.12 12.5 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 EWM28834.1 - 0.15 12.3 0.1 0.3 11.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1_Xtn PF16897.5 EWM28835.1 - 9.5e-33 112.4 0.1 1.6e-32 111.6 0.1 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EWM28835.1 - 1.2e-21 76.9 0.0 3.1e-21 75.6 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EWM28835.1 - 3e-10 39.9 0.0 5.9e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EWM28835.1 - 1.6e-06 28.2 0.0 0.017 15.1 0.0 2.4 2 0 0 2 2 2 2 Dynamin family AIG1 PF04548.16 EWM28835.1 - 0.0013 18.1 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 AIG1 family AAA_16 PF13191.6 EWM28835.1 - 0.019 15.3 0.0 0.037 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 EWM28835.1 - 0.069 13.1 0.1 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase SRPRB PF09439.10 EWM28835.1 - 0.11 11.9 0.1 0.26 10.7 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Roc PF08477.13 EWM28835.1 - 0.12 12.5 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 EWM28835.1 - 0.15 12.3 0.1 0.3 11.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain CDP-OH_P_transf PF01066.21 EWM28836.1 - 3.1e-11 43.9 0.2 7.5e-11 42.6 0.2 1.7 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase E3_UFM1_ligase PF09743.9 EWM28837.1 - 3.4e-69 233.5 0.0 4.3e-69 233.2 0.0 1.1 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 Hexapep PF00132.24 EWM28838.1 - 1.9e-13 49.6 3.4 0.00042 19.9 0.0 4.2 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EWM28838.1 - 5.2e-07 29.3 1.0 0.00026 20.7 0.0 3.5 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 EWM28838.1 - 0.12 11.3 0.0 0.37 9.7 0.0 1.8 1 1 0 1 1 1 0 L-fucokinase Fe-S_biosyn PF01521.20 EWM28839.1 - 1.7e-17 63.6 0.0 2.2e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis FAP PF07174.11 EWM28839.1 - 0.47 9.9 14.8 0.77 9.2 14.8 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) GST_C_2 PF13410.6 EWM28840.1 - 1.1e-14 54.2 0.2 3e-14 52.8 0.2 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EWM28840.1 - 3.9e-11 43.1 0.0 1.1e-10 41.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EWM28840.1 - 1.9e-07 31.2 0.0 3.2e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EWM28840.1 - 0.00024 21.2 0.0 0.00042 20.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EWM28840.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EWM28841.1 - 1.4e-14 53.8 0.2 3.7e-14 52.5 0.2 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EWM28841.1 - 5e-11 42.7 0.0 1.4e-10 41.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EWM28841.1 - 2.5e-07 30.8 0.0 4.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EWM28841.1 - 0.00031 20.9 0.0 0.00052 20.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EWM28841.1 - 0.13 12.0 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SR-25 PF10500.9 EWM28842.1 - 0.021 14.4 5.7 0.045 13.4 5.7 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein OTCace PF00185.24 EWM28844.1 - 2.8e-46 157.4 0.0 4.8e-46 156.7 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 EWM28844.1 - 5.5e-44 149.8 0.0 8.4e-44 149.2 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 EWM28845.1 - 2.8e-46 157.4 0.0 4.8e-46 156.7 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 EWM28845.1 - 5.5e-44 149.8 0.0 8.4e-44 149.2 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 EWM28846.1 - 2.7e-46 157.5 0.0 4.7e-46 156.7 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 EWM28846.1 - 5.3e-44 149.8 0.0 8.1e-44 149.2 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Peptidase_C1 PF00112.23 EWM28848.1 - 4.6e-21 75.9 0.2 7.7e-21 75.2 0.2 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EWM28848.1 - 2e-07 31.3 0.2 3.1e-07 30.7 0.2 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EWM28848.1 - 0.24 10.1 0.0 0.37 9.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase C1-like family TPR_9 PF13371.6 EWM28849.1 - 0.00083 19.5 2.1 0.00084 19.4 0.3 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EWM28849.1 - 0.0053 16.8 0.1 0.058 13.5 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EWM28850.1 - 0.00083 19.5 2.1 0.00084 19.4 0.3 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EWM28850.1 - 0.0053 16.8 0.1 0.058 13.5 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Aldo_ket_red PF00248.21 EWM28851.1 - 3.7e-41 141.3 0.0 1.1e-34 120.1 0.0 2.2 2 0 0 2 2 2 2 Aldo/keto reductase family TPR_9 PF13371.6 EWM28851.1 - 0.0033 17.6 1.4 0.0033 17.6 1.4 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EWM28851.1 - 0.13 12.0 0.1 0.31 10.8 0.1 1.6 1 0 0 1 1 1 0 TPR repeat TPR_2 PF07719.17 EWM28851.1 - 0.36 11.1 6.1 0.27 11.4 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TMEM70 PF06979.12 EWM28852.1 - 1.9e-19 70.4 3.4 2e-08 34.7 1.8 2.5 3 0 0 3 3 3 2 Assembly, mitochondrial proton-transport ATP synth complex DUF4708 PF15813.5 EWM28852.1 - 0.13 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4708) HOIP-UBA PF16678.5 EWM28853.1 - 0.11 12.5 1.0 0.24 11.4 0.0 1.8 2 0 0 2 2 2 0 HOIP UBA domain pair TetR_C_23 PF17931.1 EWM28853.1 - 0.18 11.9 1.2 0.28 11.3 0.3 1.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HK97-gp10_like PF04883.12 EWM28853.1 - 0.19 12.7 1.5 0.52 11.3 0.0 2.2 2 1 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component UBA PF00627.31 EWM28854.1 - 2.6e-09 36.8 0.9 4.3e-09 36.1 0.9 1.4 1 0 0 1 1 1 1 UBA/TS-N domain Rhomboid PF01694.22 EWM28854.1 - 0.00011 22.3 2.9 0.00011 22.3 2.9 1.6 2 0 0 2 2 2 1 Rhomboid family CUE PF02845.16 EWM28854.1 - 0.014 15.1 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 CUE domain DER1 PF04511.15 EWM28854.1 - 0.025 14.5 0.2 0.037 13.9 0.2 1.2 1 0 0 1 1 1 0 Der1-like family CTP_transf_like PF01467.26 EWM28855.1 - 8.7e-05 22.7 0.0 0.00073 19.8 0.0 2.4 1 1 0 1 1 1 1 Cytidylyltransferase-like DUF1571 PF07608.11 EWM28855.1 - 0.17 11.3 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1571) Lipase_3 PF01764.25 EWM28856.1 - 1.1e-27 96.6 0.0 1.9e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Spike_torovirin PF17072.5 EWM28856.1 - 0.022 12.0 0.5 0.029 11.5 0.5 1.0 1 0 0 1 1 1 0 Torovirinae spike glycoprotein Abhydrolase_6 PF12697.7 EWM28856.1 - 0.026 15.1 0.7 0.04 14.5 0.7 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 EWM28856.1 - 0.16 11.7 0.0 0.83 9.4 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Pkinase PF00069.25 EWM28857.1 - 5e-59 199.8 0.0 6.3e-38 130.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EWM28857.1 - 4e-26 91.8 0.2 7.2e-18 64.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EWM28857.1 - 0.00041 19.8 0.1 0.0017 17.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EWM28857.1 - 0.00045 19.6 0.0 0.0013 18.1 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EWM28857.1 - 0.0053 15.7 0.0 0.0084 15.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EWM28857.1 - 0.084 12.8 0.2 0.084 12.8 0.2 3.2 3 1 1 4 4 4 0 Phosphotransferase enzyme family DUF3987 PF13148.6 EWM28857.1 - 0.17 10.9 3.1 0.28 10.2 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) RIO1 PF01163.22 EWM28857.1 - 0.18 11.4 0.1 0.18 11.4 0.1 1.7 2 0 0 2 2 2 0 RIO1 family OmpH PF03938.14 EWM28857.1 - 0.19 12.1 5.9 0.33 11.3 5.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CENP-H PF05837.12 EWM28857.1 - 2.6 8.5 6.3 6.2 7.3 6.3 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Complex1_LYR PF05347.15 EWM28859.1 - 0.0011 19.0 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Mito_carr PF00153.27 EWM28860.1 - 7.7e-55 182.8 1.5 1.2e-19 70.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein VHP PF02209.19 EWM28862.1 - 0.093 12.8 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Villin headpiece domain zf-Mss51 PF13824.6 EWM28862.1 - 3 8.0 5.4 2.5 8.2 3.0 2.1 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Nop53 PF07767.11 EWM28863.1 - 0.001 18.6 8.6 0.001 18.6 8.6 2.2 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) HI0933_like PF03486.14 EWM28864.1 - 2.1e-40 138.7 0.4 1.4e-24 86.5 1.4 2.0 1 1 1 2 2 2 2 HI0933-like protein GIDA PF01134.22 EWM28864.1 - 0.13 11.3 0.1 0.17 11.0 0.1 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Ribonuc_red_sm PF00268.21 EWM28865.1 - 4e-116 387.4 0.2 4.7e-116 387.1 0.2 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain GDC-P PF02347.16 EWM28868.1 - 6.1e-10 38.5 0.0 7.1e-10 38.3 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage system P-protein PRIMA1 PF16101.5 EWM28870.1 - 5 7.2 10.2 2.5 8.1 8.2 1.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 HATPase_c PF02518.26 EWM28872.1 - 4.8e-21 75.4 0.5 4.5e-19 69.0 0.5 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EWM28872.1 - 1.6e-18 66.9 0.0 2.9e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EWM28872.1 - 2.7e-12 46.6 0.0 5.9e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain 4HBT PF03061.22 EWM28873.1 - 5.8e-08 33.0 0.4 0.0069 16.7 0.0 2.5 2 0 0 2 2 2 2 Thioesterase superfamily DUF4442 PF14539.6 EWM28873.1 - 0.063 13.4 0.0 0.54 10.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4442) EVE PF01878.18 EWM28874.1 - 9.1e-51 171.7 0.0 1.6e-50 170.9 0.0 1.4 1 0 0 1 1 1 1 EVE domain KIX_2 PF16987.5 EWM28875.1 - 0.013 15.4 0.3 0.026 14.5 0.3 1.4 1 0 0 1 1 1 0 KIX domain GFRP PF06399.13 EWM28876.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) Glyco_hydro_1 PF00232.18 EWM28877.1 - 9.5e-169 561.6 0.5 1.2e-168 561.3 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Nramp PF01566.18 EWM28880.1 - 3e-112 375.2 11.9 3e-112 375.2 11.9 2.0 1 1 1 2 2 2 1 Natural resistance-associated macrophage protein HMGL-like PF00682.19 EWM28880.1 - 4.8e-95 318.1 0.2 7.1e-95 317.5 0.2 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 EWM28880.1 - 1.6e-25 89.6 0.3 3e-25 88.7 0.3 1.4 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Hydrolase_4 PF12146.8 EWM28881.1 - 7.3e-27 94.2 0.0 7e-25 87.7 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EWM28881.1 - 5.1e-08 33.8 6.7 5.1e-08 33.8 6.7 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ribosomal_L27A PF00828.19 EWM28882.1 - 2.1e-22 80.2 1.7 2.9e-22 79.7 0.0 2.1 3 0 0 3 3 3 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A IBR PF01485.21 EWM28883.1 - 4.4 7.6 13.4 0.081 13.2 5.8 2.0 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain PA PF02225.22 EWM28884.1 - 7.3e-11 41.9 0.0 1.8e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 PA domain N-glycanase_C PF09113.10 EWM28884.1 - 0.0075 16.1 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Peptide-N-glycosidase F, C terminal RNB PF00773.19 EWM28885.1 - 2.9e-96 322.7 0.0 3.5e-96 322.3 0.0 1.1 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 EWM28885.1 - 1.7e-20 72.8 0.0 3.4e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_S1 PF17215.3 EWM28885.1 - 2.6e-11 43.3 0.0 5.1e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 S1 domain CSD2 PF17876.1 EWM28885.1 - 8.7e-08 32.2 0.0 2.1e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Cold shock domain TAP42 PF04177.12 EWM28886.1 - 2.4e-59 201.1 1.8 2.9e-59 200.8 1.8 1.1 1 0 0 1 1 1 1 TAP42-like family PIN_4 PF13638.6 EWM28887.1 - 0.0039 17.5 0.1 0.0052 17.1 0.1 1.2 1 0 0 1 1 1 1 PIN domain HAD PF12710.7 EWM28889.1 - 9.5e-15 55.5 0.1 2.6e-14 54.0 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EWM28889.1 - 1e-13 52.1 0.0 1.7e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EWM28889.1 - 0.011 15.1 0.0 0.033 13.6 0.0 1.6 1 1 0 1 1 1 0 Putative Phosphatase Acid_phosphat_B PF03767.14 EWM28889.1 - 0.012 15.2 0.1 0.5 9.9 0.0 2.6 2 1 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) HAD PF12710.7 EWM28890.1 - 8.9e-15 55.6 0.1 2.5e-14 54.1 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EWM28890.1 - 7.2e-14 52.6 0.0 1.2e-13 51.8 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 EWM28890.1 - 0.0052 16.4 0.1 0.5 9.9 0.0 2.6 2 1 0 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) Put_Phosphatase PF06888.12 EWM28890.1 - 0.027 13.9 0.0 0.079 12.3 0.0 1.6 1 1 0 1 1 1 0 Putative Phosphatase DUF3823_C PF18003.1 EWM28891.1 - 0.13 12.9 0.0 0.16 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3823_C) DUF3772 PF12607.8 EWM28891.1 - 2 8.2 7.4 0.29 10.9 2.8 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3772) VASt PF16016.5 EWM28895.1 - 3.5e-20 73.0 0.0 6.2e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 EWM28895.1 - 6.4e-17 61.5 0.0 1e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 GRAM domain Tad PF13400.6 EWM28895.1 - 1.4 9.2 4.3 13 6.2 3.5 2.4 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like FCH PF00611.23 EWM28896.1 - 1.9e-05 24.8 0.0 5.4e-05 23.4 0.0 1.9 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain BAR PF03114.18 EWM28896.1 - 0.0036 17.0 0.6 0.0092 15.6 0.0 1.7 2 0 0 2 2 2 1 BAR domain Dak2 PF02734.17 EWM28896.1 - 0.35 10.7 4.0 1.7 8.5 4.0 2.0 1 1 0 1 1 1 0 DAK2 domain DUF737 PF05300.11 EWM28896.1 - 8.2 6.7 8.6 2.2e+02 2.1 8.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF737) PepX_C PF08530.10 EWM28898.1 - 1.9e-23 83.6 0.0 2.4e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain PepX_C PF08530.10 EWM28899.1 - 1.9e-23 83.6 0.0 2.4e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Fungus-induced PF10917.8 EWM28900.1 - 0.1 12.9 3.0 0.24 11.7 3.0 1.6 1 0 0 1 1 1 0 Fungus-induced protein Fungus-induced PF10917.8 EWM28901.1 - 0.11 12.8 3.0 0.25 11.7 3.0 1.5 1 0 0 1 1 1 0 Fungus-induced protein Peptidase_S15 PF02129.18 EWM28902.1 - 2.8e-37 128.8 0.0 4.1e-36 125.0 0.0 2.0 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 EWM28902.1 - 0.0039 16.7 0.3 0.0076 15.7 0.3 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EWM28902.1 - 0.092 12.0 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 EWM28903.1 - 4.2e-33 115.1 0.0 1.4e-32 113.3 0.0 1.7 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 EWM28903.1 - 0.0035 16.8 0.3 0.0061 16.1 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EWM28903.1 - 0.076 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 TPT PF03151.16 EWM28905.1 - 0.00061 19.2 3.3 0.00088 18.7 3.3 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family PLDc_2 PF13091.6 EWM28907.1 - 0.0077 16.1 0.0 0.0093 15.9 0.0 1.1 1 0 0 1 1 1 1 PLD-like domain PLDc PF00614.22 EWM28907.1 - 0.19 12.0 1.0 0.68 10.2 1.0 1.8 1 1 0 1 1 1 0 Phospholipase D Active site motif PLDc_2 PF13091.6 EWM28909.1 - 1.1e-05 25.3 0.0 2.3e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 PLD-like domain DnaG_DnaB_bind PF08278.11 EWM28909.1 - 0.083 13.5 0.1 0.17 12.5 0.1 1.6 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding PIP5K PF01504.18 EWM28910.1 - 1e-17 64.3 0.1 3.9e-09 36.1 0.0 2.0 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Polysacc_lyase PF14099.6 EWM28912.1 - 7.6e-23 81.5 0.3 1.3e-22 80.7 0.3 1.2 1 0 0 1 1 1 1 Polysaccharide lyase zf-CCCH_3 PF15663.5 EWM28914.1 - 1.4e-08 34.9 6.8 2.7e-08 34.0 6.6 1.5 1 1 0 1 1 1 1 Zinc-finger containing family zf_CCCH_4 PF18345.1 EWM28914.1 - 0.0014 18.6 2.9 0.0014 18.6 2.9 3.0 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_4 PF18044.1 EWM28914.1 - 1.2 9.0 8.9 11 5.9 3.7 2.4 2 0 0 2 2 2 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EWM28914.1 - 1.5 9.4 7.9 0.39 11.3 2.6 2.6 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger DUF3593 PF12159.8 EWM28918.1 - 2.4e-25 88.4 0.5 3.5e-25 87.8 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3593) Mito_carr PF00153.27 EWM28919.1 - 2.1e-08 34.0 0.1 7.4e-08 32.2 0.1 1.8 1 1 0 1 1 1 1 Mitochondrial carrier protein T4-Gluco-transf PF09198.10 EWM28919.1 - 0.048 13.3 0.0 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 Bacteriophage T4 beta-glucosyltransferase EF-hand_7 PF13499.6 EWM28922.1 - 9.4e-22 77.2 0.0 3.3e-10 40.2 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EWM28922.1 - 3.9e-19 66.7 1.1 0.0011 18.4 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EWM28922.1 - 2.5e-18 65.7 1.4 8.3e-05 22.4 0.0 4.3 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EWM28922.1 - 3.5e-14 51.5 0.4 0.018 15.0 0.0 4.6 4 0 0 4 4 4 4 EF-hand domain 5_nucleotid_C PF02872.18 EWM28922.1 - 2.7e-13 50.4 0.0 4.8e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain EF-hand_5 PF13202.6 EWM28922.1 - 2.3e-11 42.6 2.7 0.0051 16.2 0.0 4.5 4 0 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.9 EWM28922.1 - 0.0063 16.8 0.2 0.088 13.1 0.0 2.5 3 0 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region bPH_2 PF03703.14 EWM28923.1 - 8.6e-14 51.5 0.3 1.3e-13 51.0 0.3 1.3 1 0 0 1 1 1 1 Bacterial PH domain DUF1205 PF06722.12 EWM28923.1 - 0.094 12.8 0.0 0.93 9.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1205) DUF3563 PF12086.8 EWM28924.1 - 0.048 13.4 0.1 0.13 12.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3563) PPR PF01535.20 EWM28924.1 - 0.17 12.2 0.0 1.6 9.2 0.0 2.5 2 0 0 2 2 2 0 PPR repeat WDCP PF15390.6 EWM28926.1 - 0.64 8.3 5.4 1.2 7.5 5.4 1.4 1 1 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Fip1 PF05182.13 EWM28927.1 - 4.8e-16 58.0 0.1 9.7e-16 57.0 0.1 1.5 1 0 0 1 1 1 1 Fip1 motif DUF1115 PF06544.12 EWM28927.1 - 0.11 12.6 0.0 0.11 12.6 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1115) DNA_pol_phi PF04931.13 EWM28927.1 - 3.4 5.7 14.1 6.3 4.8 14.1 1.4 1 0 0 1 1 1 0 DNA polymerase phi RNA_pol_3_Rpc31 PF11705.8 EWM28927.1 - 5.9 7.1 29.4 0.047 13.9 8.7 3.2 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 AhpC-TSA PF00578.21 EWM28928.1 - 2.1e-33 114.9 0.0 3e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EWM28928.1 - 2.9e-13 49.8 0.0 4.1e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin DIOX_N PF14226.6 EWM28929.1 - 1.7e-22 80.4 0.0 2.8e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EWM28929.1 - 8.7e-15 55.1 0.0 6.5e-07 29.8 0.0 2.6 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily Med3 PF11593.8 EWM28931.1 - 1.8 7.7 10.3 3.8 6.6 10.3 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CDK2AP PF09806.9 EWM28931.1 - 3.6 7.6 6.4 0.32 11.0 0.4 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein APOBEC_N PF08210.11 EWM28932.1 - 0.099 12.5 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain DUF2738 PF10927.8 EWM28932.1 - 0.2 10.7 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2738) Ribonuc_2-5A PF06479.12 EWM28934.1 - 2.8e-34 118.0 0.0 4.1e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 EWM28934.1 - 1.4e-27 96.8 0.0 9.8e-15 54.6 0.0 3.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EWM28934.1 - 8.7e-14 51.4 0.0 8.6e-10 38.3 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 EWM28934.1 - 0.004 16.5 0.0 0.0069 15.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ PF01011.21 EWM28935.1 - 0.0021 17.9 0.1 1.8 8.6 0.2 2.7 2 0 0 2 2 2 2 PQQ enzyme repeat PQQ_2 PF13360.6 EWM28935.1 - 0.0066 16.1 3.9 1.4 8.4 0.2 3.4 2 2 2 4 4 4 3 PQQ-like domain PQQ_3 PF13570.6 EWM28935.1 - 0.0092 16.4 5.6 4.2 8.0 0.0 4.7 5 1 0 5 5 5 2 PQQ-like domain DUF600 PF04634.12 EWM28936.1 - 0.0076 16.3 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF600 Nab1 PF04902.12 EWM28937.1 - 0.11 12.9 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 Conserved region in Nab1 Cupin_2 PF07883.11 EWM28938.1 - 0.00014 21.5 0.5 0.00056 19.6 0.5 2.0 1 1 0 1 1 1 1 Cupin domain Auxin_BP PF02041.16 EWM28938.1 - 0.017 14.8 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Auxin binding protein Cupin_2 PF07883.11 EWM28939.1 - 0.00014 21.5 0.5 0.00056 19.6 0.5 2.0 1 1 0 1 1 1 1 Cupin domain Auxin_BP PF02041.16 EWM28939.1 - 0.017 14.8 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Auxin binding protein Pkinase PF00069.25 EWM28941.1 - 1.7e-57 194.8 0.0 2.1e-57 194.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM28941.1 - 1.1e-29 103.6 0.0 1.3e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EWM28941.1 - 2.3e-07 30.0 0.0 3e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EWM28941.1 - 0.00075 18.9 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EWM28941.1 - 0.0011 19.0 1.4 0.024 14.6 0.2 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EWM28941.1 - 0.0099 15.2 0.0 0.024 14.0 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EWM28941.1 - 0.04 13.0 0.0 0.067 12.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 EWM28941.1 - 0.042 12.8 0.0 0.12 11.3 0.0 1.7 1 1 0 1 1 1 0 Haspin like kinase domain U3_assoc_6 PF08640.11 EWM28943.1 - 0.064 13.3 0.1 0.38 10.9 0.1 2.1 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 Mito_carr PF00153.27 EWM28945.1 - 2.9e-48 161.7 7.5 9.7e-21 73.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Acatn PF13000.7 EWM28946.1 - 6.8e-05 21.6 1.5 8.6e-05 21.2 1.5 1.1 1 0 0 1 1 1 1 Acetyl-coenzyme A transporter 1 Acatn PF13000.7 EWM28947.1 - 1.1e-25 90.2 0.0 1.3e-25 90.0 0.0 1.0 1 0 0 1 1 1 1 Acetyl-coenzyme A transporter 1 IRK PF01007.20 EWM28949.1 - 0.0002 21.2 0.3 0.0037 17.1 0.3 2.0 1 1 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain DNA_pol_E_B PF04042.16 EWM28950.1 - 3.8e-31 108.1 0.0 5.8e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 EWM28950.1 - 5.7e-06 26.5 0.0 8.8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Med3 PF11593.8 EWM28950.1 - 0.24 10.5 1.0 0.42 9.8 1.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal ABC1 PF03109.16 EWM28951.1 - 2.5e-20 72.8 0.0 4.7e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 EWM28951.1 - 0.00068 19.1 0.0 0.0056 16.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain WaaY PF06176.11 EWM28951.1 - 0.0015 18.2 0.2 0.14 11.7 0.1 2.3 2 0 0 2 2 2 2 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.23 EWM28951.1 - 0.004 17.1 0.1 3.8 7.4 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family DnaJ_C PF01556.18 EWM28954.1 - 0.00022 21.3 0.1 0.00022 21.3 0.1 1.5 2 0 0 2 2 2 1 DnaJ C terminal domain PdaC PF13739.6 EWM28954.1 - 0.17 12.9 3.9 0.25 12.4 3.9 1.3 1 1 0 1 1 1 0 Deacetylase PdaC CBS PF00571.28 EWM28955.1 - 1.9e-09 37.8 1.0 0.0015 18.9 0.0 2.2 2 0 0 2 2 2 2 CBS domain Shisa PF13908.6 EWM28955.1 - 0.083 13.1 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DnaJ PF00226.31 EWM28956.1 - 2.5e-10 40.3 0.0 3.4e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Kp4 PF09044.10 EWM28956.1 - 0.088 12.9 0.3 1.2 9.2 0.4 2.2 2 0 0 2 2 2 0 Kp4 Ribosomal_L5e PF17144.4 EWM28957.1 - 4.9e-80 267.3 2.3 4.9e-80 267.3 2.3 2.4 2 1 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 EWM28957.1 - 4.1e-27 94.9 3.3 4.1e-27 94.9 3.3 2.3 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 EWM28957.1 - 0.00069 20.0 0.1 0.0019 18.5 0.1 1.7 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Apelin PF15360.6 EWM28957.1 - 0.33 11.6 1.4 0.73 10.4 0.0 2.1 2 0 0 2 2 2 0 APJ endogenous ligand Torus PF16131.5 EWM28958.1 - 0.04 14.6 0.1 0.09 13.5 0.1 1.5 1 0 0 1 1 1 0 Torus domain zf-CCCH_4 PF18044.1 EWM28958.1 - 0.21 11.5 2.7 0.49 10.3 2.7 1.7 1 0 0 1 1 1 0 CCCH-type zinc finger zf-CCCH_3 PF15663.5 EWM28958.1 - 0.25 11.6 2.0 2 8.6 0.2 2.2 2 0 0 2 2 2 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 EWM28958.1 - 0.55 10.8 10.1 0.77 10.3 3.6 2.6 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 EWM28958.1 - 1.9 8.5 6.7 1.2 9.2 2.1 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Zip PF02535.22 EWM28959.1 - 0.0012 18.2 7.3 0.0016 17.8 7.3 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter CDC45 PF02724.14 EWM28959.1 - 0.0037 15.6 4.6 0.0042 15.4 4.6 1.1 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 EWM28959.1 - 0.0058 14.9 7.1 0.0066 14.7 7.1 1.0 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 EWM28959.1 - 0.024 14.1 10.9 0.029 13.8 10.9 1.1 1 0 0 1 1 1 0 SDA1 SAPS PF04499.15 EWM28959.1 - 3.6 6.3 6.4 4.5 6.0 6.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein LRR_8 PF13855.6 EWM28961.1 - 9.2e-11 41.3 0.6 6.1e-06 25.9 0.0 3.0 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 EWM28961.1 - 5.8e-09 36.1 2.8 8.3e-06 26.1 0.1 2.8 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EWM28961.1 - 2.6e-05 23.9 0.5 0.056 13.5 0.0 3.1 3 0 0 3 3 3 2 Leucine Rich repeat LRR_9 PF14580.6 EWM28961.1 - 0.00013 21.5 0.0 0.00028 20.4 0.0 1.6 1 1 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 EWM28961.1 - 0.012 16.0 6.2 0.95 10.3 0.2 3.7 3 1 0 3 3 3 0 Leucine Rich Repeat Mucin PF01456.17 EWM28962.1 - 3.8e-07 30.2 4.6 5.5e-07 29.7 4.6 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein PT PF04886.12 EWM28962.1 - 0.025 14.1 24.1 0.025 14.1 24.1 3.5 1 1 2 3 3 3 0 PT repeat Fib_alpha PF08702.10 EWM28963.1 - 0.015 15.5 7.6 0.021 15.0 7.6 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Peptidase_M41 PF01434.18 EWM28963.1 - 0.15 11.9 5.3 0.18 11.7 5.3 1.3 1 0 0 1 1 1 0 Peptidase family M41 eIF3_N PF09440.10 EWM28963.1 - 1.2 9.5 11.4 1.4 9.4 10.7 1.4 1 1 0 1 1 1 0 eIF3 subunit 6 N terminal domain UPF0242 PF06785.11 EWM28963.1 - 9.9 6.2 19.7 15 5.6 19.7 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus STPPase_N PF16891.5 EWM28966.1 - 2.2e-06 28.0 0.0 5e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain WWE PF02825.20 EWM28967.1 - 0.016 15.8 0.3 0.15 12.7 0.3 2.2 1 1 0 1 1 1 0 WWE domain PMSR PF01625.21 EWM28968.1 - 1.1e-50 171.8 0.0 1.5e-50 171.3 0.0 1.2 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase FKBP_C PF00254.28 EWM28968.1 - 8.5e-11 42.0 0.0 8.2e-10 38.9 0.0 2.1 1 1 1 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase PMSR PF01625.21 EWM28969.1 - 1.1e-50 171.8 0.0 1.5e-50 171.3 0.0 1.2 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase FKBP_C PF00254.28 EWM28969.1 - 8.5e-11 42.0 0.0 8.2e-10 38.9 0.0 2.1 1 1 1 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Transket_pyr PF02779.24 EWM28970.1 - 1.1e-14 54.6 0.0 1.5e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DUF5549 PF17703.1 EWM28970.1 - 1.2 8.8 5.0 2.2 7.9 5.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5549) CAF1C_H4-bd PF12265.8 EWM28971.1 - 2.1e-14 53.5 0.0 3.1e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Thioredoxin_4 PF13462.6 EWM28972.1 - 2.9e-10 40.6 0.0 4.3e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 EWM28972.1 - 0.039 13.7 0.4 4.2 7.1 0.1 2.6 1 1 1 2 2 2 0 DSBA-like thioredoxin domain SLH PF00395.20 EWM28972.1 - 0.16 12.0 0.0 22 5.2 0.0 2.7 3 0 0 3 3 3 0 S-layer homology domain BPL_LplA_LipB PF03099.19 EWM28973.1 - 2.2e-11 43.8 0.0 3.4e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DJ-1_PfpI PF01965.24 EWM28974.1 - 1.2e-39 135.8 0.1 1.4e-39 135.5 0.1 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI PF01965.24 EWM28975.1 - 1.6e-39 135.4 0.1 2e-39 135.1 0.1 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family adh_short PF00106.25 EWM28976.1 - 5.9e-40 136.8 0.0 2.1e-38 131.8 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EWM28976.1 - 2.9e-24 85.9 0.0 7.4e-23 81.3 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 EWM28976.1 - 6.8e-08 32.2 0.0 1.7e-06 27.6 0.0 2.2 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) KR PF08659.10 EWM28976.1 - 1.1e-06 28.7 0.0 2e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 EWM28977.1 - 5.1e-40 137.0 0.0 1.9e-38 131.9 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EWM28977.1 - 2.5e-24 86.1 0.0 6.6e-23 81.5 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 EWM28977.1 - 2.8e-08 33.5 0.0 7.7e-07 28.8 0.0 2.2 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) KR PF08659.10 EWM28977.1 - 1.1e-06 28.7 0.0 1.8e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 KR domain PPTA PF01239.22 EWM28978.1 - 1.3e-33 113.8 7.2 3.7e-10 39.2 0.4 5.2 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat PH PF00169.29 EWM28978.1 - 0.12 12.9 0.2 0.38 11.3 0.0 1.9 3 0 0 3 3 3 0 PH domain RPE65 PF03055.15 EWM28979.1 - 1.7e-28 100.0 0.0 1.9e-28 99.9 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein AAA_5 PF07728.14 EWM28981.1 - 3.7e-06 27.0 0.5 5.2e-05 23.3 0.0 2.2 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EWM28981.1 - 0.00011 22.6 0.0 0.0002 21.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EWM28981.1 - 0.00038 19.9 0.9 0.0031 16.9 0.0 2.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 EWM28981.1 - 0.00045 20.4 0.0 0.00087 19.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 EWM28981.1 - 0.00083 18.7 0.0 0.0011 18.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Sigma54_activat PF00158.26 EWM28981.1 - 0.00099 18.9 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 EWM28981.1 - 0.002 18.5 0.1 0.0042 17.5 0.1 1.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 EWM28981.1 - 0.0041 17.4 0.3 0.008 16.4 0.1 1.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EWM28981.1 - 0.0047 17.2 0.0 0.0088 16.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EWM28981.1 - 0.0078 16.8 0.0 0.015 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain MCM PF00493.23 EWM28981.1 - 0.0085 15.2 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain T2SSE PF00437.20 EWM28981.1 - 0.022 13.8 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein CPT PF07931.12 EWM28981.1 - 0.03 14.2 0.0 0.073 12.9 0.0 1.7 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein TsaE PF02367.17 EWM28981.1 - 0.032 14.2 0.0 0.32 11.0 0.0 2.1 1 1 1 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TniB PF05621.11 EWM28981.1 - 0.037 13.4 0.0 0.051 13.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein AAA_33 PF13671.6 EWM28981.1 - 0.048 13.8 0.4 0.22 11.7 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EWM28981.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EWM28981.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 EWM28981.1 - 0.15 11.5 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Trep_Strep PF09605.10 EWM28982.1 - 0.0048 16.9 8.7 0.0062 16.5 8.7 1.1 1 0 0 1 1 1 1 Hypothetical bacterial integral membrane protein (Trep_Strep) MARVEL PF01284.23 EWM28982.1 - 0.28 11.2 17.0 13 5.8 17.0 2.2 1 1 0 1 1 1 0 Membrane-associating domain ThrE PF06738.12 EWM28982.1 - 8.8 5.6 12.6 14 5.0 12.6 1.3 1 1 0 1 1 1 0 Putative threonine/serine exporter AAA_2 PF07724.14 EWM28983.1 - 6.8e-18 65.4 0.0 1.7e-17 64.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.9 EWM28983.1 - 2.8e-05 24.1 0.1 5e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 EWM28983.1 - 8.9e-05 22.9 0.0 0.00023 21.6 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Acyltransf_C PF16076.5 EWM28984.1 - 1.4e-10 41.1 0.1 2.5e-10 40.3 0.1 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.21 EWM28984.1 - 3.4e-06 26.7 0.0 6.3e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DUF3390 PF11870.8 EWM28984.1 - 0.17 12.3 0.5 1.4e+02 2.9 0.0 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3390) Putative_PNPOx PF01243.20 EWM28985.1 - 4.1e-11 42.9 0.0 8e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 EWM28985.1 - 0.00021 21.3 0.0 0.00045 20.2 0.0 1.6 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase GRP PF07172.11 EWM28985.1 - 0.41 11.4 25.1 1.3 9.8 25.1 1.9 1 1 0 1 1 1 0 Glycine rich protein family YqeY PF09424.10 EWM28987.1 - 5.7e-41 139.9 7.6 6.7e-41 139.7 7.6 1.0 1 0 0 1 1 1 1 Yqey-like protein GatB_Yqey PF02637.18 EWM28987.1 - 0.0037 17.2 4.3 0.011 15.6 4.3 1.9 1 1 0 1 1 1 1 GatB domain DUF445 PF04286.12 EWM28987.1 - 0.069 13.0 2.7 0.11 12.3 2.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Radial_spoke PF04712.12 EWM28987.1 - 0.077 11.9 0.5 0.098 11.6 0.5 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein Polyketide_cyc PF03364.20 EWM28988.1 - 7.6e-07 29.4 0.2 1.4e-06 28.5 0.2 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 EWM28988.1 - 1.4e-05 25.4 0.1 7.7e-05 23.0 0.1 2.0 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport ParcG PF10274.9 EWM28989.1 - 1.9e-42 145.5 0.0 2.3e-42 145.2 0.0 1.0 1 0 0 1 1 1 1 Parkin co-regulated protein MMS19_C PF12460.8 EWM28989.1 - 0.16 11.0 0.2 0.2 10.7 0.2 1.1 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal SET PF00856.28 EWM28991.1 - 8.9e-12 45.7 1.4 5.8e-10 39.8 1.4 2.1 1 1 0 1 1 1 1 SET domain SET PF00856.28 EWM28994.1 - 0.0029 18.0 0.0 0.0049 17.3 0.0 1.3 1 0 0 1 1 1 1 SET domain Pkinase PF00069.25 EWM28995.1 - 1.3e-30 106.7 0.0 1.8e-30 106.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM28995.1 - 9.5e-19 67.7 0.0 1.2e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EWM28995.1 - 0.036 12.8 0.0 0.061 12.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase M_domain PF12938.7 EWM28995.1 - 0.64 9.8 4.2 0.83 9.4 4.2 1.1 1 0 0 1 1 1 0 M domain of GW182 DUF998 PF06197.13 EWM28996.1 - 0.15 11.7 0.9 0.22 11.1 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF998) LysE PF01810.18 EWM28996.1 - 0.24 10.8 1.0 0.35 10.3 1.0 1.1 1 0 0 1 1 1 0 LysE type translocator DUF998 PF06197.13 EWM28997.1 - 0.15 11.7 0.9 0.22 11.1 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF998) LysE PF01810.18 EWM28997.1 - 0.24 10.8 1.0 0.35 10.3 1.0 1.1 1 0 0 1 1 1 0 LysE type translocator Pterin_4a PF01329.19 EWM29000.1 - 3.4e-30 104.0 0.5 4.3e-30 103.7 0.5 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase IF-2 PF11987.8 EWM29000.1 - 0.088 12.9 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 Translation-initiation factor 2 SBBP PF06739.11 EWM29001.1 - 0.0035 17.3 3.0 0.0067 16.4 3.0 1.5 1 0 0 1 1 1 1 Beta-propeller repeat Pkinase PF00069.25 EWM29002.1 - 0.0047 16.3 0.0 0.0056 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SURF6 PF04935.12 EWM29003.1 - 0.06 13.1 13.9 0.059 13.2 3.3 2.1 2 0 0 2 2 2 0 Surfeit locus protein 6 AATF-Che1 PF13339.6 EWM29003.1 - 0.76 10.4 7.1 0.54 10.9 1.7 2.3 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor Vfa1 PF08432.10 EWM29003.1 - 4.3 7.6 9.1 5.5 7.3 0.6 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF3381 PF11861.8 EWM29003.1 - 5 6.9 16.5 4.1 7.2 2.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Apt1 PF10351.9 EWM29004.1 - 0.12 11.2 0.8 0.17 10.7 0.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Cupin_8 PF13621.6 EWM29005.1 - 2e-54 185.0 0.0 2.5e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EWM29005.1 - 4.1e-05 23.2 0.5 0.0056 16.2 0.2 2.9 3 0 0 3 3 3 2 Cupin superfamily protein JmjC PF02373.22 EWM29005.1 - 0.037 14.5 0.0 0.079 13.4 0.0 1.5 1 0 0 1 1 1 0 JmjC domain, hydroxylase Trm112p PF03966.16 EWM29006.1 - 1.9e-06 28.3 0.0 2.3e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Trm112p-like protein Proteasome PF00227.26 EWM29007.1 - 1.5e-39 135.4 0.1 2.2e-39 134.9 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EWM29007.1 - 5.1e-15 54.8 0.4 2.2e-14 52.8 0.1 2.2 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature CENP-B_dimeris PF09026.10 EWM29009.1 - 0.24 11.8 2.8 0.43 11.0 2.4 1.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain SE PF08491.10 EWM29010.1 - 3.9e-86 288.5 0.0 5.5e-86 288.0 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 EWM29010.1 - 3.5e-14 52.8 0.1 2.8e-06 26.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EWM29010.1 - 2.2e-08 34.1 0.5 0.00032 20.4 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EWM29010.1 - 2.1e-05 24.6 0.6 5.5e-05 23.3 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EWM29010.1 - 2.9e-05 23.3 0.2 0.00011 21.5 0.1 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EWM29010.1 - 9.2e-05 21.8 0.1 0.00015 21.1 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EWM29010.1 - 0.0001 21.7 0.0 0.00053 19.3 0.0 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 EWM29010.1 - 0.00011 21.4 1.8 0.00012 21.3 0.8 1.5 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EWM29010.1 - 0.00037 19.3 0.5 0.00052 18.8 0.5 1.1 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 EWM29010.1 - 0.00076 18.9 0.2 0.0011 18.4 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EWM29010.1 - 0.036 13.3 0.0 0.055 12.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EWM29010.1 - 0.041 13.8 0.2 0.071 13.0 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 EWM29010.1 - 0.065 12.1 0.2 0.18 10.6 0.2 1.7 2 0 0 2 2 2 0 Tryptophan halogenase Shikimate_DH PF01488.20 EWM29010.1 - 0.17 12.0 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 EWM29010.1 - 0.2 12.3 0.3 0.37 11.4 0.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EWM29010.1 - 0.38 9.7 1.6 3.3 6.6 0.2 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Nup84_Nup100 PF04121.13 EWM29011.1 - 7.9e-19 67.3 0.5 8.8e-19 67.1 0.5 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 DEAD PF00270.29 EWM29012.1 - 4.3e-24 85.2 0.0 7.7e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EWM29012.1 - 1.3e-19 70.6 0.1 2.7e-19 69.5 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain WSD PF15613.6 EWM29014.1 - 1.2e-11 45.0 1.7 4.8e-11 43.0 0.0 3.0 3 0 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Spo0A_C PF08769.11 EWM29014.1 - 0.044 13.9 0.0 0.12 12.4 0.0 1.7 2 0 0 2 2 2 0 Sporulation initiation factor Spo0A C terminal DUF3130 PF11328.8 EWM29014.1 - 0.22 11.8 0.2 0.49 10.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3130 DUF2130 PF09903.9 EWM29015.1 - 0.001 18.4 0.0 0.0015 17.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2130) ATG16 PF08614.11 EWM29015.1 - 0.03 14.5 1.0 0.073 13.3 1.0 1.6 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Osmo_CC PF08946.10 EWM29015.1 - 0.18 12.1 5.1 5.5 7.3 0.4 2.4 1 1 1 2 2 2 0 Osmosensory transporter coiled coil RRP36 PF06102.12 EWM29016.1 - 4e-45 153.7 20.5 4e-45 153.7 20.5 1.8 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 Ribosomal_L13 PF00572.18 EWM29017.1 - 6.6e-50 168.5 0.2 9e-50 168.1 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 PWWP PF00855.17 EWM29018.1 - 0.0096 16.3 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 PWWP domain Y_phosphatase3 PF13350.6 EWM29020.1 - 2.7e-41 142.1 0.0 5e-41 141.2 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 EWM29020.1 - 9.7e-07 28.5 0.0 5.6e-06 26.0 0.0 2.0 2 0 0 2 2 2 1 Tyrosine phosphatase family SPX PF03105.19 EWM29020.1 - 0.36 10.7 3.0 0.44 10.4 3.0 1.1 1 0 0 1 1 1 0 SPX domain ATP-synt_Eps PF04627.13 EWM29021.1 - 2.7e-15 56.1 1.3 3.8e-15 55.6 1.3 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain DUF3721 PF12518.8 EWM29022.1 - 0.71 9.8 4.0 14 5.6 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function RRS1 PF04939.12 EWM29024.1 - 5.6e-53 179.1 1.9 8.2e-53 178.6 1.9 1.3 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) WYL_2 PF10902.8 EWM29024.1 - 0.18 12.2 0.3 0.37 11.2 0.3 1.4 1 0 0 1 1 1 0 WYL_2, Sm-like SH3 beta-barrel fold PRKCSH PF07915.13 EWM29025.1 - 1.9e-20 73.7 0.6 4.9e-12 46.7 0.2 2.5 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 EWM29025.1 - 1.1e-10 41.4 5.0 0.00026 20.7 0.3 3.8 1 1 2 3 3 3 3 Glucosidase II beta subunit-like protein HlyE PF06109.13 EWM29026.1 - 0.2 10.9 0.0 0.25 10.6 0.0 1.1 1 0 0 1 1 1 0 Haemolysin E (HlyE) TPK_catalytic PF04263.16 EWM29027.1 - 1.3e-33 115.6 0.0 2.5e-33 114.7 0.0 1.5 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 EWM29027.1 - 1.1e-13 50.7 0.0 2.2e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Atx10homo_assoc PF09759.9 EWM29029.1 - 7.2e-07 29.2 2.7 0.014 15.4 0.0 3.7 4 0 0 4 4 4 2 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 EWM29029.1 - 0.00014 21.8 1.9 0.42 10.7 0.1 4.2 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat RNA_pol_Rpb2_6 PF00562.28 EWM29030.1 - 2.4e-124 415.4 0.1 3.2e-124 414.9 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EWM29030.1 - 1.1e-53 181.7 0.1 1.5e-53 181.3 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EWM29030.1 - 3.7e-42 144.1 0.2 7.9e-42 143.0 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EWM29030.1 - 8.8e-32 109.4 0.1 1.9e-31 108.3 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 EWM29030.1 - 2.2e-25 88.6 0.0 5.1e-25 87.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 EWM29030.1 - 5.6e-20 71.4 0.1 1.3e-19 70.3 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 EWM29030.1 - 9.6e-18 64.5 0.4 2.2e-17 63.3 0.4 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Beta-lactamase PF00144.24 EWM29032.1 - 2.4e-35 122.4 0.0 3.7e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 EWM29032.1 - 0.041 13.5 0.0 14 5.2 0.0 2.6 2 1 1 3 3 3 0 Beta-lactamase enzyme family SET PF00856.28 EWM29033.1 - 3e-17 63.5 0.0 2.2e-16 60.7 0.0 1.9 1 1 0 1 1 1 1 SET domain Alba PF01918.21 EWM29034.1 - 0.016 15.0 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 Alba E2F_TDP PF02319.20 EWM29035.1 - 4.5e-31 106.7 3.1 2.9e-18 65.7 0.1 2.2 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain DUF3824 PF12868.7 EWM29035.1 - 8.6 7.0 8.4 1.2 9.8 1.0 2.3 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) ArfGap PF01412.18 EWM29036.1 - 1.9e-15 56.9 0.2 2.1e-15 56.8 0.2 1.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Opiods_neuropep PF01160.18 EWM29036.1 - 0.0037 17.3 0.9 0.0053 16.8 0.9 1.2 1 0 0 1 1 1 1 Vertebrate endogenous opioids neuropeptide ZF-HD_dimer PF04770.12 EWM29036.1 - 0.029 14.7 0.3 0.034 14.5 0.3 1.2 1 0 0 1 1 1 0 ZF-HD protein dimerisation region zf-B_box PF00643.24 EWM29036.1 - 0.031 14.4 2.4 0.059 13.5 2.4 1.5 1 1 0 1 1 1 0 B-box zinc finger HSA PF07529.13 EWM29037.1 - 6.4e-13 48.8 0.3 6.4e-13 48.8 0.3 3.9 3 0 0 3 3 3 1 HSA SNF2_N PF00176.23 EWM29037.1 - 1e-07 31.0 0.0 3e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Myb_DNA-bind_6 PF13921.6 EWM29037.1 - 0.042 14.1 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain SDA1 PF05285.12 EWM29037.1 - 0.11 11.9 23.9 0.3 10.5 11.8 3.0 2 0 0 2 2 2 0 SDA1 Laminin_II PF06009.12 EWM29038.1 - 0.0014 18.7 2.4 0.0014 18.7 2.4 4.7 3 3 2 5 5 5 2 Laminin Domain II Leu_zip PF15294.6 EWM29038.1 - 6.8 6.1 49.1 1.6 8.2 2.6 4.2 1 1 2 4 4 4 0 Leucine zipper Spc7 PF08317.11 EWM29038.1 - 7.2 5.4 69.3 0.044 12.7 5.1 4.9 2 1 3 5 5 5 0 Spc7 kinetochore protein NGP1NT PF08153.12 EWM29039.1 - 1.1e-43 148.4 0.0 2.4e-43 147.4 0.0 1.5 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 EWM29039.1 - 6e-15 55.3 7.6 2.5e-14 53.3 0.0 3.3 4 0 0 4 4 3 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EWM29039.1 - 1e-06 28.3 0.4 5.4e-05 22.8 0.1 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EWM29039.1 - 5.9e-06 26.3 0.0 1.6e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 RsgA GTPase Arf PF00025.21 EWM29039.1 - 1.5e-05 24.5 0.1 0.093 12.2 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 EWM29039.1 - 0.012 15.8 0.2 6.8 6.9 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase BUD22 PF09073.10 EWM29039.1 - 0.082 12.2 37.8 0.14 11.5 37.8 1.3 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 EWM29039.1 - 0.098 12.1 44.7 0.049 13.1 42.4 1.7 2 0 0 2 2 2 0 SDA1 CDC45 PF02724.14 EWM29039.1 - 0.61 8.3 32.1 0.98 7.6 32.1 1.2 1 0 0 1 1 1 0 CDC45-like protein SID-1_RNA_chan PF13965.6 EWM29039.1 - 1.1 7.5 3.6 1.5 7.2 3.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SAPS PF04499.15 EWM29039.1 - 2.4 6.8 15.6 3.8 6.2 15.6 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 EWM29039.1 - 2.4 6.2 49.7 3.5 5.7 49.7 1.1 1 0 0 1 1 1 0 Nop14-like family FancD2 PF14631.6 EWM29039.1 - 2.7 5.3 10.0 3.8 4.8 10.0 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Neur_chan_memb PF02932.16 EWM29039.1 - 3.4 7.6 5.4 6.3 6.8 5.4 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NPR3 PF03666.13 EWM29039.1 - 3.9 6.2 17.7 5.8 5.6 17.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CobT PF06213.12 EWM29039.1 - 4.1 6.7 39.2 7.7 5.8 39.2 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Mpp10 PF04006.12 EWM29039.1 - 4.3 5.6 46.0 6.5 5.1 46.0 1.1 1 0 0 1 1 1 0 Mpp10 protein Lin-8 PF03353.15 EWM29039.1 - 6.5 6.2 23.9 11 5.5 23.9 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DAGAT PF03982.13 EWM29040.1 - 3.5e-22 78.7 0.0 3.4e-20 72.2 0.0 2.1 2 0 0 2 2 2 2 Diacylglycerol acyltransferase SEP PF08059.13 EWM29040.1 - 0.048 14.2 0.0 0.088 13.4 0.0 1.4 1 0 0 1 1 1 0 SEP domain UDPGP PF01704.18 EWM29041.1 - 1.4e-11 43.7 0.0 2.8e-11 42.7 0.0 1.4 2 0 0 2 2 2 1 UTP--glucose-1-phosphate uridylyltransferase B12D PF06522.11 EWM29042.1 - 4.2e-05 23.3 0.0 0.0001 22.0 0.0 1.6 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit GTP_cyclohydro2 PF00925.20 EWM29043.1 - 1.9e-57 193.4 0.0 4.7e-57 192.1 0.0 1.6 2 0 0 2 2 2 1 GTP cyclohydrolase II DHBP_synthase PF00926.19 EWM29043.1 - 1.8e-05 24.3 0.0 0.21 11.1 0.0 3.8 3 1 0 3 3 3 2 3,4-dihydroxy-2-butanone 4-phosphate synthase Importin_rep_4 PF18808.1 EWM29045.1 - 3e-05 24.2 0.0 0.0017 18.6 0.0 3.3 1 1 0 1 1 1 1 Importin repeat IFRD PF05004.13 EWM29045.1 - 0.052 12.7 0.0 0.33 10.0 0.0 2.4 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) Adaptin_N PF01602.20 EWM29045.1 - 0.095 11.2 0.3 4.7 5.7 0.0 3.2 2 1 0 3 3 3 0 Adaptin N terminal region AP_endonuc_2 PF01261.24 EWM29045.1 - 0.13 11.7 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel HEAT PF02985.22 EWM29045.1 - 2.5 8.6 16.4 1e+02 3.6 0.1 8.5 8 0 0 8 8 8 0 HEAT repeat PhyH PF05721.13 EWM29048.1 - 5.4e-54 183.6 0.1 6.4e-54 183.4 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) HhH-GPD PF00730.25 EWM29049.1 - 1.5e-13 51.1 0.0 3.5e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NADH-G_4Fe-4S_3 PF10588.9 EWM29049.1 - 0.15 11.6 1.7 2.1 7.9 0.0 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Epimerase PF01370.21 EWM29050.1 - 1.8e-10 40.7 0.0 1.1e-09 38.1 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EWM29050.1 - 0.00021 20.5 0.0 0.0094 15.1 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 EWM29050.1 - 0.0018 17.7 0.0 0.057 12.8 0.0 2.3 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 EWM29050.1 - 0.049 13.7 0.0 0.099 12.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RNA_pol_Rpb5_C PF01191.19 EWM29051.1 - 5.2e-31 106.3 0.8 8.3e-31 105.7 0.1 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 EWM29051.1 - 1e-18 67.7 0.0 1.5e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain CTP_synth_N PF06418.14 EWM29051.1 - 0.098 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 CTP synthase N-terminus Coagulase PF08764.10 EWM29051.1 - 0.13 12.4 0.1 0.17 12.0 0.1 1.1 1 0 0 1 1 1 0 Staphylococcus aureus coagulase Asp PF00026.23 EWM29052.1 - 5.2e-20 72.1 0.0 2.9e-06 26.9 0.0 4.2 3 1 0 3 3 3 3 Eukaryotic aspartyl protease TAXi_N PF14543.6 EWM29052.1 - 2.4e-10 40.9 0.6 4.9e-09 36.7 0.6 2.3 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EWM29052.1 - 5.4e-06 26.3 0.0 0.036 13.9 0.0 3.2 3 0 0 3 3 3 2 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 EWM29052.1 - 0.00024 21.7 0.2 8 7.2 0.0 3.5 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 EWM29052.1 - 0.084 13.4 0.0 9.9 6.8 0.0 3.3 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease AATase PF07247.12 EWM29053.1 - 7.5e-12 44.6 0.0 9.1e-11 41.0 0.0 2.1 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.20 EWM29053.1 - 0.00035 19.4 0.2 0.0012 17.6 0.0 1.8 2 0 0 2 2 2 1 Condensation domain RRM_1 PF00076.22 EWM29054.1 - 3.6e-72 238.2 0.6 2.9e-15 55.8 0.2 6.3 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EWM29054.1 - 1.7e-06 27.6 0.0 0.25 10.9 0.0 4.1 3 1 1 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transgly PF00912.22 EWM29054.1 - 0.00014 21.4 0.0 0.0003 20.3 0.0 1.5 1 0 0 1 1 1 1 Transglycosylase RRM_7 PF16367.5 EWM29054.1 - 0.0069 16.5 0.0 17 5.6 0.0 4.5 5 0 0 5 5 5 1 RNA recognition motif RRM_Rrp7 PF17799.1 EWM29054.1 - 0.098 12.5 0.0 24 4.7 0.0 3.5 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain BRAP2 PF07576.12 EWM29054.1 - 0.18 12.0 0.0 0.61 10.4 0.0 1.8 2 0 0 2 2 2 0 BRCA1-associated protein 2 DUF2098 PF09871.9 EWM29054.1 - 1.2 9.6 0.0 1.2 9.6 0.0 3.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2098) Mito_carr PF00153.27 EWM29056.1 - 5.9e-69 228.1 0.0 1.8e-22 79.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EWM29056.1 - 0.002 17.3 0.0 3.5 6.7 0.0 3.1 3 0 0 3 3 3 2 Gammaproteobacterial serine protease PALP PF00291.25 EWM29059.1 - 4.2e-65 220.1 1.7 5.4e-65 219.7 1.7 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NAD_binding_7 PF13241.6 EWM29059.1 - 0.023 15.1 0.0 0.056 13.9 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Abhydrolase_1 PF00561.20 EWM29060.1 - 1.4e-06 28.2 0.0 1.8e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EWM29060.1 - 5.8e-06 27.1 0.1 7e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EWM29060.1 - 3.5e-05 23.2 0.0 0.00014 21.2 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 EWM29060.1 - 0.002 17.7 0.0 0.0031 17.0 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 EWM29060.1 - 0.0036 17.1 0.0 0.0057 16.4 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF900 PF05990.12 EWM29060.1 - 0.0054 16.3 0.0 0.0083 15.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) LIDHydrolase PF10230.9 EWM29060.1 - 0.013 15.0 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DLH PF01738.18 EWM29060.1 - 0.015 14.8 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Palm_thioest PF02089.15 EWM29060.1 - 0.033 14.0 0.0 0.05 13.4 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Lipase_3 PF01764.25 EWM29060.1 - 0.035 14.0 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) LCAT PF02450.15 EWM29060.1 - 0.16 11.1 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Cyclin_N PF00134.23 EWM29061.1 - 1.4e-13 50.7 0.0 2.5e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 EWM29061.1 - 0.067 13.2 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Transcription factor TFIIB repeat Spem1 PF15670.5 EWM29061.1 - 1.3 8.5 6.7 2.7 7.5 0.0 2.2 2 0 0 2 2 2 0 Spermatid maturation protein 1 Ras PF00071.22 EWM29062.1 - 7.4e-59 198.0 0.1 9.5e-59 197.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EWM29062.1 - 7.3e-36 123.0 0.1 1.1e-35 122.4 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EWM29062.1 - 1.1e-12 47.8 0.1 1.5e-12 47.3 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EWM29062.1 - 8.7e-07 29.0 0.1 1.3e-06 28.4 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EWM29062.1 - 0.00062 19.7 0.1 0.028 14.3 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EWM29062.1 - 0.00078 19.0 0.1 0.0025 17.4 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain KAP_NTPase PF07693.14 EWM29062.1 - 0.004 16.4 0.0 0.0079 15.5 0.0 1.3 1 1 0 1 1 1 1 KAP family P-loop domain AAA_22 PF13401.6 EWM29062.1 - 0.0083 16.4 0.1 0.038 14.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EWM29062.1 - 0.0093 15.7 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.12 EWM29062.1 - 0.0096 15.3 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 EWM29062.1 - 0.01 16.2 0.1 0.024 15.0 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 EWM29062.1 - 0.046 13.7 0.0 0.55 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 EWM29062.1 - 0.056 14.0 0.0 0.095 13.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter SRPRB PF09439.10 EWM29062.1 - 0.087 12.2 0.0 0.17 11.3 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 EWM29062.1 - 0.1 12.0 0.0 0.39 10.1 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 EWM29062.1 - 0.19 11.2 0.0 0.41 10.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Pro_CA PF00484.19 EWM29063.1 - 8.3e-35 120.4 0.3 3.1e-34 118.5 0.0 1.8 2 0 0 2 2 2 1 Carbonic anhydrase Minor_capsid_3 PF12691.7 EWM29063.1 - 0.035 14.5 0.0 0.059 13.7 0.0 1.3 1 0 0 1 1 1 0 Minor capsid protein from bacteriophage Tup_N PF08581.10 EWM29063.1 - 0.067 13.5 1.1 0.12 12.7 1.1 1.4 1 0 0 1 1 1 0 Tup N-terminal MitMem_reg PF13012.6 EWM29063.1 - 0.11 12.9 0.1 0.24 11.8 0.1 1.6 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function PPR_2 PF13041.6 EWM29064.1 - 1.9e-115 376.9 0.0 7e-13 48.5 0.0 17.0 10 4 7 17 17 16 15 PPR repeat family PPR PF01535.20 EWM29064.1 - 1.6e-110 353.9 16.7 3.7e-07 30.0 0.0 21.1 21 0 0 21 21 21 16 PPR repeat PPR_1 PF12854.7 EWM29064.1 - 5.1e-83 272.4 0.0 1.1e-06 28.2 0.0 18.4 18 1 0 18 18 18 14 PPR repeat PPR_3 PF13812.6 EWM29064.1 - 1.5e-77 255.6 0.0 2.2e-12 46.9 0.0 12.4 10 2 1 12 12 12 10 Pentatricopeptide repeat domain PPR_long PF17177.4 EWM29064.1 - 6.3e-43 146.6 0.7 2.4e-14 53.2 0.0 6.7 4 3 2 6 6 6 4 Pentacotripeptide-repeat region of PRORP ANAPC3 PF12895.7 EWM29064.1 - 4.1e-13 49.4 2.3 0.27 11.5 0.0 8.1 7 1 1 8 8 8 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EWM29064.1 - 1e-10 41.9 15.2 0.49 10.9 0.8 9.7 9 1 1 10 10 10 2 Tetratricopeptide repeat MRP-S27 PF10037.9 EWM29064.1 - 1.3e-10 40.7 0.0 0.021 13.7 0.0 5.8 5 2 3 8 8 8 5 Mitochondrial 28S ribosomal protein S27 TPR_14 PF13428.6 EWM29064.1 - 7.4e-10 38.8 33.0 1.4 10.0 0.0 15.4 12 2 6 18 18 17 1 Tetratricopeptide repeat Clathrin PF00637.20 EWM29064.1 - 4.3e-09 36.4 0.0 0.61 10.0 0.0 6.9 6 2 2 8 8 7 2 Region in Clathrin and VPS HrpB1_HrpK PF09613.10 EWM29064.1 - 2.8e-07 30.2 21.3 0.053 13.2 0.1 8.9 5 2 5 11 11 11 2 Bacterial type III secretion protein (HrpB1_HrpK) TPR_7 PF13176.6 EWM29064.1 - 2.9e-07 30.1 14.0 25 5.2 0.0 12.2 15 0 0 15 15 13 0 Tetratricopeptide repeat COX5A PF02284.16 EWM29064.1 - 4.7e-06 26.6 0.5 0.073 13.1 0.0 6.0 6 2 2 8 8 7 1 Cytochrome c oxidase subunit Va ECSIT PF06239.11 EWM29064.1 - 0.00017 20.8 0.0 27 3.8 0.0 6.5 7 3 1 8 8 8 0 Evolutionarily conserved signalling intermediate in Toll pathway Glyco_trans_4_3 PF12000.8 EWM29064.1 - 0.001 18.8 0.2 2.7 7.7 0.0 4.1 3 1 1 4 4 4 1 Glycosyl transferase family 4 group ELYS PF13934.6 EWM29064.1 - 0.0021 18.1 0.4 15 5.5 0.3 4.1 3 1 1 4 4 4 0 Nuclear pore complex assembly SRP_TPR_like PF17004.5 EWM29064.1 - 0.012 15.6 0.0 48 4.0 0.0 5.0 4 1 1 5 5 5 0 Putative TPR-like repeat TPR_12 PF13424.6 EWM29064.1 - 0.019 15.2 22.8 5.3 7.4 0.9 10.6 13 1 0 13 13 13 0 Tetratricopeptide repeat Ank_4 PF13637.6 EWM29064.1 - 0.025 15.1 0.1 11 6.8 0.0 4.5 3 2 2 5 5 4 0 Ankyrin repeats (many copies) TPR_4 PF07721.14 EWM29064.1 - 0.041 14.5 33.0 0.39 11.5 0.1 11.3 12 0 0 12 12 12 0 Tetratricopeptide repeat TPR_2 PF07719.17 EWM29064.1 - 3.6 7.9 22.1 56 4.2 0.1 9.5 12 0 0 12 12 9 0 Tetratricopeptide repeat HRM PF02793.22 EWM29064.1 - 3.9 7.8 9.4 33 4.9 0.0 5.6 4 2 1 5 5 4 0 Hormone receptor domain TPR_10 PF13374.6 EWM29064.1 - 4.4 7.3 18.3 18 5.3 0.2 6.9 7 0 0 7 7 6 0 Tetratricopeptide repeat Synaptobrevin PF00957.21 EWM29065.1 - 8.2e-18 64.0 0.4 1.3e-17 63.3 0.4 1.3 1 0 0 1 1 1 1 Synaptobrevin Snf7 PF03357.21 EWM29066.1 - 3.4e-12 46.3 4.9 4.8e-12 45.8 4.9 1.2 1 0 0 1 1 1 1 Snf7 zf-ribbon_3 PF13248.6 EWM29066.1 - 0.2 11.1 4.0 0.35 10.4 4.0 1.4 1 0 0 1 1 1 0 zinc-ribbon domain FAD_binding_2 PF00890.24 EWM29067.1 - 1.6e-124 416.2 4.2 2.2e-124 415.8 4.2 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EWM29067.1 - 2e-43 147.4 2.6 2.9e-43 146.9 2.6 1.2 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 EWM29067.1 - 5e-06 26.0 0.3 3.8e-05 23.1 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EWM29067.1 - 6.6e-05 22.3 0.2 0.011 15.0 0.1 2.4 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 EWM29067.1 - 0.0002 20.5 4.6 0.0014 17.7 3.3 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.24 EWM29067.1 - 0.0014 18.3 1.0 0.003 17.2 0.5 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EWM29067.1 - 0.0091 15.3 0.4 0.0091 15.3 0.4 2.4 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 EWM29067.1 - 0.02 13.6 2.2 0.038 12.7 1.4 1.9 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 EWM29067.1 - 0.045 12.8 0.0 0.087 11.9 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.7 EWM29067.1 - 1 8.6 11.7 0.16 11.3 6.5 2.3 2 1 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EWM29068.1 - 4.1e-114 381.9 0.8 5.6e-114 381.5 0.8 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EWM29068.1 - 1.7e-43 147.7 2.6 2.4e-43 147.2 2.6 1.2 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term FAD_binding_2 PF00890.24 EWM29069.1 - 2.2e-114 382.8 0.8 2.6e-114 382.6 0.8 1.0 1 0 0 1 1 1 1 FAD binding domain Med26 PF08711.11 EWM29070.1 - 2.7e-09 36.9 0.2 6.7e-09 35.6 0.2 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain SesA PF17107.5 EWM29070.1 - 0.44 10.8 2.9 1.3 9.2 1.0 2.4 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases SR-25 PF10500.9 EWM29070.1 - 3.6 7.1 34.8 0.048 13.3 13.1 2.6 1 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein PNGaseA PF12222.8 EWM29071.1 - 1.2e-54 185.8 2.2 1e-51 176.2 0.0 2.8 2 1 0 2 2 2 2 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF2151 PF10221.9 EWM29072.1 - 5.5 5.5 30.6 7.1 5.1 30.6 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator DUF3123 PF11321.8 EWM29072.1 - 5.6 7.7 10.8 0.86 10.3 1.4 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3123) GST_N_3 PF13417.6 EWM29073.1 - 4.2e-13 49.5 0.0 8.8e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EWM29073.1 - 6e-08 32.9 0.0 1.2e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EWM29073.1 - 1.4e-07 31.7 0.0 2.4e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EWM29073.1 - 9.5e-05 22.4 0.0 0.0002 21.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EWM29073.1 - 0.004 17.3 0.0 0.03 14.5 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EWM29073.1 - 0.0041 17.8 0.0 0.0089 16.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Glutaredoxin PF00462.24 EWM29073.1 - 0.005 17.0 0.1 0.019 15.2 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin GST_C_3 PF14497.6 EWM29073.1 - 0.024 14.8 0.0 0.055 13.7 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EWM29073.1 - 0.074 13.6 0.3 0.3 11.7 0.0 2.1 2 1 1 3 3 3 0 Glutathione S-transferase, C-terminal domain Pkinase PF00069.25 EWM29074.1 - 4.7e-68 229.4 0.0 6.1e-68 229.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM29074.1 - 1.2e-32 113.3 0.0 1.8e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 EWM29074.1 - 4.8e-10 39.9 0.0 9.4e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 EWM29074.1 - 1.3e-07 31.8 0.2 3e-07 30.6 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 EWM29074.1 - 1.2e-05 25.6 1.6 6.5e-05 23.3 1.6 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain Kdo PF06293.14 EWM29074.1 - 0.017 14.5 0.1 0.029 13.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EWM29074.1 - 0.023 13.6 0.1 0.035 13.0 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 EWM29074.1 - 0.15 11.0 0.5 0.25 10.3 0.5 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 EWM29074.1 - 0.18 11.4 0.3 0.32 10.6 0.3 1.3 1 0 0 1 1 1 0 RIO1 family PepX_C PF08530.10 EWM29076.1 - 1.6e-23 83.8 0.0 4.6e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 EWM29076.1 - 6e-23 81.8 0.6 4.2e-22 79.0 0.0 2.2 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 EWM29076.1 - 0.14 11.6 0.0 0.32 10.4 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family Myotub-related PF06602.14 EWM29077.1 - 1.5e-115 385.9 0.0 2.1e-115 385.4 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 EWM29077.1 - 0.0004 20.4 0.0 0.00066 19.7 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family HTH_29 PF13551.6 EWM29077.1 - 0.048 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix DUF846 PF05832.12 EWM29078.1 - 1.9e-54 183.4 12.6 2.5e-54 183.1 12.6 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) YwiC PF14256.6 EWM29078.1 - 0.0075 16.6 5.1 0.29 11.4 0.3 2.1 2 0 0 2 2 2 2 YwiC-like protein DUF4972 PF16342.5 EWM29078.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4972) DUF2207 PF09972.9 EWM29078.1 - 5.2 5.7 5.2 6.2 5.5 0.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Thr_synth_N PF14821.6 EWM29080.1 - 1.5e-21 76.4 0.0 3.4e-21 75.2 0.0 1.7 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 EWM29080.1 - 1.8e-10 40.7 0.0 0.00042 19.8 0.0 3.2 2 1 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme SUIM_assoc PF16619.5 EWM29080.1 - 0.0098 15.9 0.5 0.053 13.6 0.2 2.5 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 RLL PF10036.9 EWM29081.1 - 1.5e-44 152.8 0.0 1.8e-44 152.6 0.0 1.0 1 0 0 1 1 1 1 RNA transcription, translation and transport factor protein EH_Signature PF15611.6 EWM29081.1 - 0.052 13.0 0.1 0.081 12.3 0.1 1.2 1 0 0 1 1 1 0 EH_Signature domain DUF1440 PF07274.12 EWM29081.1 - 0.17 12.3 0.0 0.26 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1440) RNase_P_Rpp14 PF01900.19 EWM29082.1 - 2.1e-25 89.0 0.0 2.6e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family RNase_P_Rpp14 PF01900.19 EWM29083.1 - 2.1e-25 89.0 0.0 2.6e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family Pkinase PF00069.25 EWM29084.1 - 2.6e-22 79.4 0.0 8.1e-22 77.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM29084.1 - 5.2e-19 68.5 0.0 1.8e-18 66.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase HATPase_c_3 PF13589.6 EWM29084.1 - 1e-16 61.0 0.0 2.4e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Morc6_S5 PF17942.1 EWM29084.1 - 5.4e-14 52.4 0.0 9.3e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Morc6 ribosomal protein S5 domain 2-like zf-CW PF07496.15 EWM29084.1 - 1.8e-07 31.1 2.0 3.5e-07 30.2 2.0 1.5 1 0 0 1 1 1 1 CW-type Zinc Finger HATPase_c PF02518.26 EWM29084.1 - 6.2e-05 23.5 0.0 0.00014 22.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase U79_P34 PF03064.16 EWM29084.1 - 0.51 9.7 6.2 0.9 8.9 6.2 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Prefoldin_2 PF01920.20 EWM29085.1 - 3.8e-16 59.0 1.0 4.9e-16 58.6 1.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit STAT_alpha PF01017.20 EWM29085.1 - 0.0025 17.7 0.3 0.0033 17.4 0.3 1.1 1 0 0 1 1 1 1 STAT protein, all-alpha domain RasGAP_C PF03836.15 EWM29085.1 - 0.0071 16.5 0.2 0.01 16.0 0.2 1.2 1 0 0 1 1 1 1 RasGAP C-terminus FapA PF03961.13 EWM29085.1 - 0.017 13.8 0.1 0.041 12.5 0.0 1.6 1 1 1 2 2 2 0 Flagellar Assembly Protein A JAKMIP_CC3 PF16034.5 EWM29085.1 - 0.028 14.3 2.6 0.087 12.8 0.2 2.0 2 0 0 2 2 2 0 JAKMIP CC3 domain TnpV PF14198.6 EWM29085.1 - 0.039 13.9 0.6 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 Transposon-encoded protein TnpV Occludin_ELL PF07303.13 EWM29085.1 - 0.048 14.4 0.4 1.3 9.7 0.0 2.0 2 0 0 2 2 2 0 Occludin homology domain RmuC PF02646.16 EWM29085.1 - 0.071 12.2 4.0 2.4 7.2 0.2 2.0 1 1 1 2 2 2 0 RmuC family DUF5082 PF16888.5 EWM29085.1 - 0.092 13.0 5.3 1.1 9.6 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) APG6_N PF17675.1 EWM29085.1 - 0.18 12.3 9.2 0.088 13.3 1.6 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region Seryl_tRNA_N PF02403.22 EWM29085.1 - 0.32 11.3 3.7 1.7 8.9 0.3 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain bZIP_1 PF00170.21 EWM29085.1 - 6.6 6.9 8.6 5.6 7.1 1.4 2.3 2 0 0 2 2 2 0 bZIP transcription factor adh_short_C2 PF13561.6 EWM29086.1 - 1.4e-53 181.8 0.9 1.6e-53 181.6 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EWM29086.1 - 5.5e-50 169.6 3.4 6.7e-50 169.3 3.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EWM29086.1 - 1e-11 45.1 2.5 1.5e-11 44.6 2.5 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EWM29086.1 - 0.00032 20.2 0.4 0.00084 18.9 0.4 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EWM29086.1 - 0.0016 17.5 0.1 0.0021 17.1 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EWM29086.1 - 0.0052 16.2 0.1 0.0076 15.7 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 EWM29086.1 - 0.0053 16.7 0.2 0.0083 16.0 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain OHA PF14418.6 EWM29086.1 - 0.11 12.4 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 OST-HTH Associated domain SpoU_methylase PF00588.19 EWM29087.1 - 1.7e-27 96.4 0.0 2.3e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family WSC PF01822.19 EWM29088.1 - 2.9e-08 33.8 7.9 2.9e-08 33.8 7.9 2.2 2 0 0 2 2 2 1 WSC domain Lectin_C PF00059.21 EWM29088.1 - 0.00029 21.5 0.0 0.0013 19.4 0.0 2.1 2 0 0 2 2 2 1 Lectin C-type domain DUF2844 PF11005.8 EWM29088.1 - 0.2 11.7 0.0 0.38 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2844) Disaggr_repeat PF06848.11 EWM29089.1 - 0.12 12.0 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Disaggregatase related repeat Nuf2 PF03800.14 EWM29090.1 - 1.8e-41 141.5 0.3 3.5e-41 140.6 0.3 1.5 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 EWM29090.1 - 4.7e-16 58.9 18.8 4.7e-16 58.9 18.8 5.0 2 1 3 5 5 5 2 Designed helical repeat protein 10 domain Seryl_tRNA_N PF02403.22 EWM29090.1 - 0.16 12.2 45.0 1.9 8.8 11.1 4.2 1 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Prominin PF05478.11 EWM29090.1 - 0.29 9.1 14.1 0.085 10.8 1.7 2.1 1 1 0 2 2 2 0 Prominin Golgin_A5 PF09787.9 EWM29090.1 - 0.73 9.2 41.5 0.83 9.1 18.0 2.5 1 1 1 2 2 2 0 Golgin subfamily A member 5 BLOC1_2 PF10046.9 EWM29090.1 - 1 9.7 17.7 0.54 10.6 2.2 4.0 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sec34 PF04136.15 EWM29090.1 - 2.9 7.7 13.6 4.2 7.2 2.2 3.6 3 1 1 4 4 4 0 Sec34-like family NAD_binding_5 PF07994.12 EWM29092.1 - 7.6e-140 465.8 0.0 9e-140 465.6 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 EWM29092.1 - 4.5e-48 162.0 0.2 8.8e-48 161.1 0.2 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase YCII PF03795.14 EWM29094.1 - 9.8e-13 48.3 0.0 2.2e-11 44.0 0.0 2.3 2 0 0 2 2 2 1 YCII-related domain Nuc_sug_transp PF04142.15 EWM29095.1 - 1.5e-113 379.2 16.4 1.8e-113 378.9 16.4 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 EWM29095.1 - 4e-06 27.0 1.9 4e-06 27.0 1.9 2.5 2 0 0 2 2 2 1 EamA-like transporter family UAA PF08449.11 EWM29095.1 - 5.6e-05 22.5 15.3 6.2e-05 22.3 13.7 1.8 1 1 0 1 1 1 1 UAA transporter family CRT-like PF08627.10 EWM29095.1 - 0.00017 20.7 1.5 0.00017 20.7 1.5 2.3 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 EWM29095.1 - 0.01 15.2 20.0 0.039 13.3 4.7 3.0 2 2 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.6 EWM29095.1 - 0.011 15.3 9.3 0.023 14.3 9.3 1.5 1 0 0 1 1 1 0 Putative multidrug resistance efflux transporter DUF1230 PF06799.11 EWM29095.1 - 0.029 14.5 0.3 0.029 14.5 0.3 2.2 2 0 0 2 2 2 0 Conserved in the green lineage and diatoms 27 DUF1129 PF06570.11 EWM29095.1 - 5.7 6.4 7.1 0.34 10.4 0.1 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) DMT_6 PF04342.12 EWM29095.1 - 7.4 6.8 13.8 0.22 11.7 3.2 2.9 2 1 1 3 3 3 0 Putative member of DMT superfamily (DUF486) Citrate_bind PF16114.5 EWM29096.1 - 7.6e-90 299.2 0.0 1.3e-89 298.4 0.0 1.4 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 EWM29096.1 - 1.4e-22 80.3 0.1 1.7e-19 70.1 0.1 2.8 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 EWM29096.1 - 1.9e-15 57.0 0.0 7.8e-15 55.0 0.0 2.1 3 0 0 3 3 3 1 CoA-ligase ATP-grasp_2 PF08442.10 EWM29096.1 - 3.3e-10 39.9 0.0 5.8e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CoA_binding PF02629.19 EWM29096.1 - 7.4e-09 36.2 0.0 2.2e-08 34.7 0.0 1.9 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.6 EWM29096.1 - 0.00063 19.6 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain ABC1 PF03109.16 EWM29098.1 - 5.2e-26 91.2 0.0 1.2e-25 90.0 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EWM29098.1 - 2.9e-05 24.1 2.0 0.00068 19.6 0.6 2.6 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.25 EWM29098.1 - 0.027 13.8 0.3 0.062 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein kinase domain Tetraspanin PF00335.20 EWM29099.1 - 1.1e-07 31.8 14.3 3.7e-07 30.1 14.3 1.7 1 1 0 1 1 1 1 Tetraspanin family DUF778 PF05608.12 EWM29100.1 - 9e-33 114.2 8.3 8.8e-18 65.3 0.2 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF778) adh_short PF00106.25 EWM29101.1 - 1.1e-30 106.5 0.1 2.1e-28 99.1 0.0 2.9 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EWM29101.1 - 5.5e-17 62.1 0.0 3.9e-15 56.1 0.0 2.4 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM29101.1 - 1.2e-06 28.6 0.2 1.3e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 KR domain 2-Hacid_dh_C PF02826.19 EWM29101.1 - 0.073 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GSHPx PF00255.19 EWM29103.1 - 6.2e-39 131.9 0.4 9.1e-39 131.4 0.4 1.3 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 EWM29103.1 - 0.0002 21.2 0.1 0.0003 20.7 0.1 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EWM29103.1 - 0.00025 20.8 0.1 0.00041 20.1 0.1 1.4 1 0 0 1 1 1 1 Redoxin tRNA-synt_2 PF00152.20 EWM29104.1 - 2.8e-76 256.6 0.0 3.6e-76 256.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EWM29104.1 - 3.5e-17 62.1 0.3 6.9e-17 61.2 0.3 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EWM29104.1 - 0.00025 20.6 0.0 0.091 12.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) ATG16 PF08614.11 EWM29105.1 - 0.00047 20.4 3.2 0.00047 20.4 3.2 6.1 4 1 3 7 7 7 1 Autophagy protein 16 (ATG16) HMMR_N PF15905.5 EWM29105.1 - 0.0013 18.3 11.8 0.0013 18.3 11.8 4.0 3 1 0 3 3 3 2 Hyaluronan mediated motility receptor N-terminal ORC5_C PF14630.6 EWM29106.1 - 3.4e-33 115.4 0.0 1.2e-32 113.6 0.0 2.0 2 1 0 2 2 2 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 EWM29106.1 - 4.3e-09 37.0 2.8 1.2e-07 32.3 2.8 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EWM29106.1 - 0.033 14.5 0.0 0.13 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EWM29106.1 - 0.19 12.2 0.0 0.4 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase RNA_pol_3_Rpc31 PF11705.8 EWM29106.1 - 1.7 8.8 18.1 0.69 10.1 12.8 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 EWM29106.1 - 6.9 5.9 10.0 12 5.1 10.0 1.3 1 0 0 1 1 1 0 NOA36 protein SLBP_RNA_bind PF15247.6 EWM29107.1 - 3.1e-26 91.3 2.9 3.1e-26 91.3 2.9 2.1 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain SecE PF00584.20 EWM29108.1 - 9.1e-15 54.3 0.0 1.3e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex DEAD PF00270.29 EWM29109.1 - 1.5e-41 142.0 0.0 4.9e-41 140.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EWM29109.1 - 3.5e-30 104.6 0.5 1.7e-29 102.4 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain zf-CCHC PF00098.23 EWM29109.1 - 0.0027 17.7 1.5 0.0027 17.7 1.5 2.3 3 0 0 3 3 3 1 Zinc knuckle ResIII PF04851.15 EWM29109.1 - 0.019 15.0 0.0 0.061 13.3 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 EWM29109.1 - 0.049 12.9 0.0 0.091 12.0 0.0 1.5 1 0 0 1 1 1 0 SecA DEAD-like domain OxoDH_E1alpha_N PF12573.8 EWM29110.1 - 0.1 12.4 3.2 0.4 10.5 0.1 2.8 2 0 0 2 2 2 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal Amidase PF01425.21 EWM29112.1 - 1.2e-59 202.4 0.0 1.4e-59 202.3 0.0 1.0 1 0 0 1 1 1 1 Amidase TAP_C PF03943.13 EWM29113.1 - 1.4 8.6 4.0 3.2 7.5 0.0 2.8 3 0 0 3 3 3 0 TAP C-terminal domain ArfGap PF01412.18 EWM29114.1 - 8.1e-15 54.9 0.3 1.2e-14 54.4 0.3 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF2451 PF10474.9 EWM29115.1 - 8.5e-47 159.9 0.0 2.1e-46 158.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 EWM29115.1 - 3.1e-09 36.5 2.6 5.3e-09 35.8 2.6 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex TPT PF03151.16 EWM29116.1 - 8e-20 71.4 20.3 1e-19 71.0 20.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family CBP_GIL PF10995.8 EWM29116.1 - 0.25 10.0 0.3 0.33 9.6 0.3 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis GIL DUF2897 PF11446.8 EWM29116.1 - 0.56 10.1 2.3 17 5.4 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) TMCO5 PF14992.6 EWM29116.1 - 0.9 9.1 1.7 1.5 8.4 1.7 1.3 1 0 0 1 1 1 0 TMCO5 family TPT PF03151.16 EWM29117.1 - 9.5e-20 71.1 20.1 1.2e-19 70.8 20.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family CBP_GIL PF10995.8 EWM29117.1 - 0.31 9.7 0.3 0.42 9.2 0.3 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis GIL DUF2897 PF11446.8 EWM29117.1 - 0.79 9.7 2.3 20 5.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) GXWXG PF14231.6 EWM29119.1 - 0.019 15.1 0.5 0.06 13.4 0.5 2.0 1 1 0 1 1 1 0 GXWXG protein tRNA-synt_1 PF00133.22 EWM29120.1 - 7.8e-192 638.7 0.0 1.1e-191 638.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EWM29120.1 - 4.9e-29 101.3 0.0 8.5e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EWM29120.1 - 8.7e-20 70.8 0.0 4.6e-11 42.1 0.0 3.2 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EWM29120.1 - 0.00029 20.3 0.0 0.5 9.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.6 EWM29120.1 - 0.012 15.2 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 DehI PF10778.9 EWM29120.1 - 0.18 12.0 0.6 1.4 9.1 0.2 2.4 3 0 0 3 3 3 0 Halocarboxylic acid dehydrogenase DehI zf-FPG_IleRS PF06827.14 EWM29120.1 - 6 6.8 7.3 32 4.5 7.3 2.1 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS SHS2_Rpb7-N PF03876.17 EWM29121.1 - 0.17 12.3 0.0 0.66 10.4 0.0 1.9 2 0 0 2 2 2 0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Glyco_hydro_3 PF00933.21 EWM29122.1 - 6.7e-64 216.3 0.0 8.8e-64 215.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EWM29122.1 - 1.2e-35 123.3 0.0 2e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 EWM29122.1 - 6.6e-11 42.2 0.0 1.4e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain zf-C2H2_12 PF18658.1 EWM29123.1 - 0.0064 16.0 1.5 0.014 14.9 1.5 1.6 1 0 0 1 1 1 1 Zinc-finger C2H2-type adh_short PF00106.25 EWM29124.1 - 7.1e-20 71.3 0.0 1.6e-13 50.6 0.0 2.7 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EWM29124.1 - 2.5e-06 27.3 0.1 0.00013 21.6 0.0 2.4 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM29124.1 - 0.031 14.2 0.0 1.8 8.4 0.0 2.2 2 0 0 2 2 2 0 KR domain PRTP PF01366.18 EWM29125.1 - 0.13 10.3 3.1 0.21 9.6 3.1 1.2 1 0 0 1 1 1 0 Herpesvirus processing and transport protein CorA PF01544.18 EWM29125.1 - 1.1 8.5 3.4 1.5 8.1 1.0 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Sec10 PF07393.11 EWM29126.1 - 5.2e-47 160.7 0.9 1.9e-19 69.6 0.0 4.0 4 0 0 4 4 4 4 Exocyst complex component Sec10 DUF5536 PF17688.1 EWM29126.1 - 0.095 12.6 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5536) BT1 PF03092.16 EWM29128.1 - 2.5e-48 164.6 15.5 3.4e-31 108.1 8.5 2.5 2 1 1 3 3 3 2 BT1 family PUCC PF03209.15 EWM29128.1 - 0.1 11.6 9.8 0.13 11.3 7.1 2.3 1 1 1 2 2 2 0 PUCC protein KH_6 PF15985.5 EWM29129.1 - 2e-10 40.9 0.0 3.3e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 KH domain Tubulin PF00091.25 EWM29130.1 - 6.4e-69 232.1 0.0 1e-68 231.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EWM29130.1 - 2.5e-47 160.2 0.3 5.3e-47 159.1 0.3 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EWM29130.1 - 5.3e-06 26.7 0.0 1.5e-05 25.3 0.0 1.7 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 EWM29130.1 - 0.015 14.5 0.0 0.029 13.5 0.0 1.4 1 0 0 1 1 1 0 Tubulin like Tubulin_3 PF14881.6 EWM29130.1 - 0.074 12.7 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Tubulin domain UPF0669 PF17065.5 EWM29130.1 - 0.087 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative cytokine, C6ORF120 RhoGAP PF00620.27 EWM29131.1 - 3.5e-21 75.6 0.1 7.5e-21 74.5 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.23 EWM29131.1 - 4e-09 36.4 0.0 7.1e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MCM PF00493.23 EWM29132.1 - 2.8e-65 219.5 0.0 6.4e-59 198.8 0.0 2.2 2 0 0 2 2 2 2 MCM P-loop domain MCM_OB PF17207.3 EWM29132.1 - 3.2e-24 85.2 0.3 6.2e-24 84.2 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 EWM29132.1 - 6.1e-09 35.6 0.1 1.3e-05 24.7 0.0 2.6 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EWM29132.1 - 8.5e-07 29.1 0.0 1.9e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MCM_N PF14551.6 EWM29132.1 - 5.4e-06 26.9 0.1 1.1e-05 26.0 0.1 1.5 1 0 0 1 1 1 1 MCM N-terminal domain AAA_16 PF13191.6 EWM29132.1 - 0.034 14.5 0.0 0.088 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 EWM29132.1 - 0.049 13.0 0.0 0.087 12.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_3 PF07726.11 EWM29132.1 - 0.073 12.9 0.0 0.22 11.4 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MCM_lid PF17855.1 EWM29132.1 - 0.12 12.8 0.1 0.25 11.8 0.1 1.6 1 0 0 1 1 1 0 MCM AAA-lid domain COX16 PF14138.6 EWM29133.1 - 2.7e-13 50.2 1.0 1.2e-12 48.1 1.0 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 EMP24_GP25L PF01105.24 EWM29134.1 - 7.1e-34 117.3 0.0 8.4e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF1206 PF06724.11 EWM29134.1 - 0.063 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) MeaB PF03308.16 EWM29135.1 - 8.2e-81 270.9 0.0 3.2e-79 265.7 0.0 2.0 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 EWM29135.1 - 8.3e-09 35.3 0.0 2.9e-08 33.5 0.0 1.9 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 EWM29135.1 - 0.00014 21.7 0.0 0.00041 20.2 0.0 1.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 EWM29135.1 - 0.0023 18.5 0.3 0.011 16.3 0.1 2.1 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 EWM29135.1 - 0.0055 16.8 0.0 0.011 15.8 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.6 EWM29135.1 - 0.0059 16.3 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EWM29135.1 - 0.0068 16.5 0.1 0.021 14.9 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.6 EWM29135.1 - 0.0074 16.0 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EWM29135.1 - 0.01 15.1 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 EWM29135.1 - 0.014 15.1 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EWM29135.1 - 0.018 15.3 0.0 0.046 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EWM29135.1 - 0.018 15.5 0.0 0.04 14.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter KAP_NTPase PF07693.14 EWM29135.1 - 0.022 14.0 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain AAA_33 PF13671.6 EWM29135.1 - 0.057 13.6 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EWM29135.1 - 0.059 13.7 0.1 0.13 12.6 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EWM29135.1 - 0.08 13.4 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GTP_EFTU PF00009.27 EWM29135.1 - 0.081 12.5 0.0 4 6.9 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_23 PF13476.6 EWM29135.1 - 0.082 13.4 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EWM29135.1 - 0.094 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 NTPase KTI12 PF08433.10 EWM29135.1 - 0.097 12.1 0.1 0.27 10.6 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 RNA_helicase PF00910.22 EWM29135.1 - 0.16 12.4 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF2256 PF10013.9 EWM29135.1 - 1.1 9.5 6.7 2 8.6 1.0 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) EMP70 PF02990.16 EWM29136.1 - 9.4e-206 684.5 7.6 1.3e-205 684.0 7.6 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 DUF4229 PF14012.6 EWM29136.1 - 1.1 9.4 0.0 1.1 9.4 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4229) MFS_1 PF07690.16 EWM29137.1 - 1.7e-29 102.9 10.1 2.3e-29 102.4 10.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EWM29137.1 - 5e-12 45.4 6.8 6.3e-12 45.1 6.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EWM29137.1 - 6.4e-05 21.6 1.6 8e-05 21.2 1.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ATG22 PF11700.8 EWM29137.1 - 0.035 12.8 1.5 0.061 11.9 1.5 1.3 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like CLTH PF10607.9 EWM29139.1 - 6.3e-24 84.5 0.0 9.1e-24 84.0 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain U-box PF04564.15 EWM29139.1 - 0.0081 16.3 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 U-box domain DUF2183 PF09949.9 EWM29140.1 - 0.00069 19.9 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) DUF2183 PF09949.9 EWM29141.1 - 0.00065 20.0 0.0 0.0015 18.8 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) S1 PF00575.23 EWM29144.1 - 1e-12 48.2 0.0 6.1e-07 29.7 0.0 2.6 2 0 0 2 2 2 2 S1 RNA binding domain RNase_II_C_S1 PF18614.1 EWM29144.1 - 7.5e-09 35.4 1.1 0.00033 20.5 0.1 2.4 2 0 0 2 2 2 2 RNase II-type exonuclease C-terminal S1 domain DUF2423 PF10338.9 EWM29145.1 - 0.00015 22.0 3.1 0.00015 22.0 3.1 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2423) zf-CCHC_5 PF14787.6 EWM29145.1 - 0.013 15.2 1.6 4.1 7.2 0.0 2.6 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Clathrin PF00637.20 EWM29146.1 - 1.8e-184 605.0 32.0 4.5e-31 107.6 0.4 8.4 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 EWM29146.1 - 1.5e-26 92.0 0.2 1.5e-26 92.0 0.2 3.9 5 0 0 5 5 5 1 Clathrin-H-link Clathrin_propel PF01394.20 EWM29146.1 - 5.7e-09 35.8 0.0 0.04 14.2 0.0 5.3 5 0 0 5 5 5 2 Clathrin propeller repeat Clathrin-link PF09268.10 EWM29146.1 - 6.3e-05 22.3 0.1 0.00016 20.9 0.1 1.8 1 0 0 1 1 1 1 Clathrin, heavy-chain linker TPR_14 PF13428.6 EWM29146.1 - 7.2e-05 23.3 8.0 4.8 8.3 0.0 9.2 9 1 0 9 9 9 1 Tetratricopeptide repeat TPR_2 PF07719.17 EWM29146.1 - 8.2e-05 22.4 3.6 1.8 8.9 0.1 6.2 5 0 0 5 5 5 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 EWM29146.1 - 0.00072 18.7 1.8 0.12 11.3 0.1 3.1 4 0 0 4 4 4 2 Coatomer WD associated region TPR_1 PF00515.28 EWM29146.1 - 0.068 13.0 6.1 1.3 8.9 0.3 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EWM29146.1 - 0.11 12.7 3.3 0.2 11.9 0.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EWM29146.1 - 0.6 10.5 9.8 6.4 7.2 0.1 6.0 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EWM29146.1 - 1.1 10.1 5.6 4.4 8.1 0.1 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat HCO3_cotransp PF00955.21 EWM29147.1 - 2.6e-119 399.4 11.1 3.4e-64 217.5 0.7 2.2 1 1 1 2 2 2 2 HCO3- transporter family NdhL PF10716.9 EWM29148.1 - 0.042 13.8 0.9 0.062 13.3 0.9 1.2 1 0 0 1 1 1 0 NADH dehydrogenase transmembrane subunit RSN1_7TM PF02714.15 EWM29149.1 - 3.4e-57 193.9 26.1 5.5e-57 193.2 26.1 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EWM29149.1 - 9.9e-33 113.1 0.1 9.9e-33 113.1 0.1 2.6 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EWM29149.1 - 5.3e-28 98.4 0.0 7.4e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter NTP_transf_2 PF01909.23 EWM29150.1 - 0.00077 19.7 0.0 0.002 18.4 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 EWM29150.1 - 0.0018 18.5 0.0 0.0091 16.2 0.0 2.3 1 0 0 1 1 1 1 Cid1 family poly A polymerase LON_substr_bdg PF02190.16 EWM29151.1 - 2.4e-12 47.2 0.0 3.2e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 EWM29151.1 - 2.7e-09 36.7 10.6 6.1e-09 35.6 10.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EWM29151.1 - 3.5e-07 30.0 9.3 3.5e-07 30.0 9.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EWM29151.1 - 4e-07 29.8 12.5 8e-07 28.8 12.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EWM29151.1 - 8.4e-07 29.2 9.9 2.3e-06 27.8 9.9 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EWM29151.1 - 8.4e-06 25.7 8.2 2.1e-05 24.4 8.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EWM29151.1 - 1.9e-05 24.5 9.6 3.9e-05 23.5 9.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 EWM29151.1 - 0.00017 21.3 1.9 0.00045 19.9 1.9 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 EWM29151.1 - 0.002 18.4 5.1 0.0057 16.9 5.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 EWM29151.1 - 0.0034 17.5 9.7 0.0075 16.4 9.7 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 EWM29151.1 - 0.012 15.8 10.2 0.012 15.8 10.2 2.0 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EWM29151.1 - 3 7.8 19.9 0.041 13.7 12.1 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 SHMT PF00464.19 EWM29153.1 - 7.5e-177 587.9 0.0 8.9e-177 587.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 EWM29153.1 - 9e-06 25.2 0.0 1.9e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Macro PF01661.21 EWM29153.1 - 0.0056 16.7 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 Macro domain SHMT PF00464.19 EWM29154.1 - 8.3e-177 587.7 0.0 1e-176 587.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 EWM29154.1 - 9.9e-06 25.0 0.0 2.1e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Macro PF01661.21 EWM29154.1 - 0.0044 17.1 0.1 0.013 15.6 0.0 1.8 2 0 0 2 2 2 1 Macro domain GDP_Man_Dehyd PF16363.5 EWM29155.1 - 7.6e-63 212.9 0.0 2.2e-62 211.4 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EWM29155.1 - 1.8e-54 184.8 0.0 2.3e-54 184.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EWM29155.1 - 3.1e-17 62.5 0.0 4.3e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EWM29155.1 - 4.2e-14 52.4 0.0 2.3e-13 49.9 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EWM29155.1 - 9.6e-14 51.1 0.0 3.2e-13 49.4 0.0 1.8 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EWM29155.1 - 2.2e-09 36.9 0.0 3.9e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein KR PF08659.10 EWM29155.1 - 6.5e-07 29.4 0.2 1.8e-06 28.0 0.2 1.7 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 EWM29155.1 - 2.5e-05 23.8 0.2 0.001 18.6 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.6 EWM29155.1 - 0.00023 21.1 0.0 0.00098 19.1 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding DAO PF01266.24 EWM29155.1 - 0.042 13.4 0.0 0.26 10.8 0.0 1.9 1 1 1 2 2 2 0 FAD dependent oxidoreductase Sacchrp_dh_NADP PF03435.18 EWM29155.1 - 0.14 12.4 0.1 0.47 10.7 0.1 1.9 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain CDC45 PF02724.14 EWM29157.1 - 0.1 10.9 3.5 0.14 10.5 3.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Spt5_N PF11942.8 EWM29157.1 - 0.23 12.5 11.4 0.47 11.5 11.4 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal COPI_C PF06957.11 EWM29157.1 - 1.1 7.9 3.2 1.4 7.6 3.2 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus NOA36 PF06524.12 EWM29157.1 - 2.7 7.2 6.5 4.9 6.4 6.5 1.4 1 0 0 1 1 1 0 NOA36 protein Tcf25 PF04910.14 EWM29158.1 - 7.3e-47 160.1 0.0 9.9e-47 159.7 0.0 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_12 PF13424.6 EWM29158.1 - 0.11 12.8 0.2 0.4 11.0 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Pro_isomerase PF00160.21 EWM29161.1 - 9.6e-40 136.4 0.0 1.6e-39 135.7 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 EWM29161.1 - 6.4e-16 57.9 0.1 1.1e-15 57.2 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EWM29161.1 - 0.18 11.4 0.0 0.4 10.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MTHFR PF02219.17 EWM29162.1 - 8e-105 350.3 0.0 1.2e-104 349.7 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase UQ_con PF00179.26 EWM29163.1 - 1.2e-51 174.1 0.0 1.3e-51 173.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EWM29163.1 - 0.0049 16.6 0.0 0.0062 16.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EWM29163.1 - 0.011 16.0 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 EWM29163.1 - 0.063 13.1 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 UEV domain AAA PF00004.29 EWM29164.1 - 2.6e-13 50.6 0.1 2.5e-12 47.4 0.0 2.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 EWM29164.1 - 4.9e-11 42.6 0.1 4.9e-11 42.6 0.1 2.1 2 1 0 2 2 2 1 AAA lid domain AAA_5 PF07728.14 EWM29164.1 - 0.00074 19.5 0.7 0.044 13.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EWM29164.1 - 0.0016 17.8 0.8 0.091 12.1 0.1 2.8 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 EWM29164.1 - 0.0073 16.6 2.1 0.56 10.5 0.2 3.4 3 1 0 4 4 4 1 AAA domain AAA_7 PF12775.7 EWM29164.1 - 0.01 15.4 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 EWM29164.1 - 0.018 14.7 1.8 0.16 11.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain DUF5401 PF17380.2 EWM29164.1 - 0.02 13.0 2.8 0.027 12.6 2.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) IstB_IS21 PF01695.17 EWM29164.1 - 0.021 14.6 0.1 0.059 13.1 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.6 EWM29164.1 - 0.083 13.4 1.4 0.16 12.5 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EWM29164.1 - 0.089 13.0 0.1 0.089 13.0 0.1 2.4 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 EWM29164.1 - 0.092 12.7 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 NTPase ResIII PF04851.15 EWM29164.1 - 0.094 12.7 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_33 PF13671.6 EWM29164.1 - 0.1 12.8 0.0 0.1 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EWM29164.1 - 0.11 12.2 0.4 1.3 8.7 0.1 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain APS_kinase PF01583.20 EWM29164.1 - 0.12 12.3 0.5 1.8 8.4 0.0 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_19 PF13245.6 EWM29164.1 - 0.14 12.5 0.7 0.43 10.9 0.1 2.1 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 EWM29164.1 - 0.14 11.8 0.3 0.29 10.8 0.1 1.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EWM29164.1 - 0.22 11.9 1.2 0.63 10.4 0.1 2.1 1 1 1 2 2 2 0 AAA ATPase domain SKIP_SNW PF02731.15 EWM29164.1 - 0.26 10.9 6.2 0.44 10.2 6.2 1.3 1 0 0 1 1 1 0 SKIP/SNW domain AAA PF00004.29 EWM29165.1 - 2.6e-13 50.6 0.1 2.5e-12 47.4 0.0 2.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 EWM29165.1 - 4.9e-11 42.6 0.1 4.9e-11 42.6 0.1 2.1 2 1 0 2 2 2 1 AAA lid domain AAA_5 PF07728.14 EWM29165.1 - 0.00074 19.5 0.7 0.044 13.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EWM29165.1 - 0.0016 17.8 0.8 0.091 12.1 0.1 2.8 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 EWM29165.1 - 0.0073 16.6 2.1 0.56 10.5 0.2 3.4 3 1 0 4 4 4 1 AAA domain AAA_7 PF12775.7 EWM29165.1 - 0.01 15.4 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 EWM29165.1 - 0.018 14.7 1.8 0.16 11.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain DUF5401 PF17380.2 EWM29165.1 - 0.02 13.0 2.8 0.027 12.6 2.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) IstB_IS21 PF01695.17 EWM29165.1 - 0.021 14.6 0.1 0.059 13.1 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.6 EWM29165.1 - 0.083 13.4 1.4 0.16 12.5 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EWM29165.1 - 0.089 13.0 0.1 0.089 13.0 0.1 2.4 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 EWM29165.1 - 0.092 12.7 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 NTPase ResIII PF04851.15 EWM29165.1 - 0.094 12.7 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_33 PF13671.6 EWM29165.1 - 0.1 12.8 0.0 0.1 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EWM29165.1 - 0.11 12.2 0.4 1.3 8.7 0.1 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain APS_kinase PF01583.20 EWM29165.1 - 0.12 12.3 0.5 1.8 8.4 0.0 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_19 PF13245.6 EWM29165.1 - 0.14 12.5 0.7 0.43 10.9 0.1 2.1 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 EWM29165.1 - 0.14 11.8 0.3 0.29 10.8 0.1 1.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EWM29165.1 - 0.22 11.9 1.2 0.63 10.4 0.1 2.1 1 1 1 2 2 2 0 AAA ATPase domain SKIP_SNW PF02731.15 EWM29165.1 - 0.26 10.9 6.2 0.44 10.2 6.2 1.3 1 0 0 1 1 1 0 SKIP/SNW domain TPR_14 PF13428.6 EWM29167.1 - 8.1e-50 163.2 25.6 2e-05 25.0 0.0 16.4 4 4 13 17 17 17 10 Tetratricopeptide repeat TPR_2 PF07719.17 EWM29167.1 - 1.2e-49 162.4 19.0 0.00095 19.1 0.0 17.6 19 0 0 19 19 18 12 Tetratricopeptide repeat TPR_19 PF14559.6 EWM29167.1 - 7.4e-39 132.1 4.4 0.0029 18.1 0.0 10.6 8 3 2 11 11 11 9 Tetratricopeptide repeat TPR_16 PF13432.6 EWM29167.1 - 1.3e-38 131.4 14.0 8.7e-06 26.3 0.8 11.3 11 1 0 11 11 11 6 Tetratricopeptide repeat TPR_12 PF13424.6 EWM29167.1 - 4.5e-32 110.2 27.3 6.1e-05 23.2 1.5 12.2 9 4 2 11 11 11 7 Tetratricopeptide repeat TPR_8 PF13181.6 EWM29167.1 - 1.9e-30 102.5 5.7 0.044 14.0 0.0 14.3 15 0 0 15 15 15 5 Tetratricopeptide repeat TPR_17 PF13431.6 EWM29167.1 - 6.2e-29 98.3 0.0 0.015 15.6 0.0 14.4 16 0 0 16 16 15 6 Tetratricopeptide repeat TPR_1 PF00515.28 EWM29167.1 - 2e-24 84.4 2.7 0.01 15.6 0.0 13.1 14 0 0 14 14 12 3 Tetratricopeptide repeat TPR_7 PF13176.6 EWM29167.1 - 2.5e-18 64.7 15.4 0.15 12.2 0.0 12.5 13 1 1 14 14 12 4 Tetratricopeptide repeat Suf PF05843.14 EWM29167.1 - 1e-16 61.8 3.9 0.0031 17.6 0.0 6.7 5 3 1 7 7 7 4 Suppressor of forked protein (Suf) TPR_11 PF13414.6 EWM29167.1 - 3e-15 55.6 0.0 0.00034 20.2 0.0 7.6 9 1 1 10 10 7 2 TPR repeat TPR_6 PF13174.6 EWM29167.1 - 2.9e-13 49.5 20.9 0.26 12.0 0.0 14.3 15 0 0 15 15 14 1 Tetratricopeptide repeat TPR_15 PF13429.6 EWM29167.1 - 6.3e-13 48.6 11.2 0.011 14.9 0.0 8.0 2 2 2 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 EWM29167.1 - 2.2e-11 43.7 17.6 0.0045 17.1 0.0 8.2 6 2 3 9 9 9 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EWM29167.1 - 2.8e-09 37.1 1.0 3.4 7.9 0.0 7.1 6 2 2 8 8 7 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 EWM29167.1 - 4.7e-08 32.8 18.7 0.03 13.7 4.1 6.3 2 1 5 7 7 7 3 MalT-like TPR region Coatomer_E PF04733.14 EWM29167.1 - 1.2e-07 31.5 0.4 0.046 13.1 0.0 5.1 5 1 0 5 5 5 2 Coatomer epsilon subunit Mad3_BUB1_I PF08311.12 EWM29167.1 - 1.6e-07 31.3 8.0 22 5.0 0.0 10.0 10 2 1 11 11 10 0 Mad3/BUB1 homology region 1 DUF4810 PF16068.5 EWM29167.1 - 1.4e-06 28.7 3.4 2.4 8.8 0.0 7.3 6 2 2 9 9 7 1 Domain of unknown function (DUF4810) PPR_1 PF12854.7 EWM29167.1 - 3.6e-06 26.6 15.5 4.5 7.1 0.1 8.3 8 0 0 8 8 8 2 PPR repeat PPR PF01535.20 EWM29167.1 - 2e-05 24.5 28.9 4.1 7.9 0.1 11.5 14 0 0 14 14 9 1 PPR repeat TPR_10 PF13374.6 EWM29167.1 - 3e-05 23.7 30.1 2.2 8.3 0.4 11.3 13 0 0 13 13 12 2 Tetratricopeptide repeat NARP1 PF12569.8 EWM29167.1 - 7.2e-05 21.9 7.8 0.074 12.0 0.0 5.0 5 1 0 6 6 6 2 NMDA receptor-regulated protein 1 TPR_4 PF07721.14 EWM29167.1 - 9.1e-05 22.7 27.5 1.2 9.9 0.4 11.0 12 0 0 12 12 10 1 Tetratricopeptide repeat TPR_21 PF09976.9 EWM29167.1 - 0.00029 20.6 10.9 0.69 9.6 0.0 5.7 3 2 2 5 5 5 1 Tetratricopeptide repeat-like domain MIT PF04212.18 EWM29167.1 - 0.0034 17.4 2.1 77 3.5 0.0 6.9 8 0 0 8 8 5 0 MIT (microtubule interacting and transport) domain TAtT PF16811.5 EWM29167.1 - 0.0072 15.7 1.6 8.6 5.6 0.0 3.9 4 0 0 4 4 4 0 TRAP transporter T-component TPR_20 PF14561.6 EWM29167.1 - 0.084 13.2 5.6 29 5.1 0.1 5.5 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_5 PF12688.7 EWM29167.1 - 0.092 13.0 9.9 0.38 11.0 0.2 4.7 5 0 0 5 5 5 0 Tetratrico peptide repeat SNAP PF14938.6 EWM29167.1 - 0.14 11.5 1.5 48 3.2 0.1 4.3 2 1 1 4 4 4 0 Soluble NSF attachment protein, SNAP ANAPC5 PF12862.7 EWM29167.1 - 0.24 11.5 2.6 15 5.8 0.4 4.1 3 1 1 4 4 3 0 Anaphase-promoting complex subunit 5 PPR_2 PF13041.6 EWM29167.1 - 5.6 7.2 16.1 36 4.7 0.1 8.1 9 1 0 9 9 8 0 PPR repeat family Isochorismatase PF00857.20 EWM29168.1 - 0.0012 19.1 0.0 0.58 10.3 0.0 2.5 2 0 0 2 2 2 2 Isochorismatase family PAS_9 PF13426.7 EWM29169.1 - 4e-16 59.1 0.0 1.3e-15 57.5 0.0 1.8 2 0 0 2 2 2 1 PAS domain bZIP_2 PF07716.15 EWM29169.1 - 1.3e-07 31.5 10.5 1.3e-07 31.5 10.5 1.7 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 EWM29169.1 - 6.8e-07 29.3 9.3 1.7e-06 28.0 9.3 1.6 1 0 0 1 1 1 1 bZIP transcription factor PAS PF00989.25 EWM29169.1 - 6.2e-06 26.2 0.0 1.4e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EWM29169.1 - 0.00038 20.7 0.0 0.00073 19.8 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 EWM29169.1 - 0.00059 20.1 0.0 0.001 19.3 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 EWM29169.1 - 0.012 15.6 0.0 0.031 14.3 0.0 1.7 1 0 0 1 1 1 0 PAS domain bZIP_Maf PF03131.17 EWM29169.1 - 0.13 12.8 9.7 0.11 13.0 4.8 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor CRAL_TRIO PF00650.20 EWM29171.1 - 1.6e-16 60.5 0.2 2.4e-16 59.9 0.2 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EWM29171.1 - 0.13 12.4 0.1 0.22 11.7 0.1 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 EWM29173.1 - 1.1e-16 61.0 0.2 1.5e-16 60.5 0.2 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EWM29173.1 - 0.099 12.8 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EWM29173.1 - 0.11 12.7 0.1 0.22 11.8 0.1 1.5 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain Lipase_GDSL PF00657.22 EWM29174.1 - 3e-14 53.5 0.0 3.8e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 EWM29174.1 - 6.4e-09 36.5 0.1 5.2e-08 33.5 0.1 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Pkinase PF00069.25 EWM29175.1 - 2.8e-73 246.6 0.0 4.8e-73 245.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM29175.1 - 2e-32 112.5 0.0 6.4e-32 110.8 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase FHA PF00498.26 EWM29175.1 - 8.4e-16 58.1 0.6 2e-15 56.9 0.1 1.9 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.6 EWM29175.1 - 4.1e-09 36.2 0.0 7.9e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EWM29175.1 - 1.1e-05 24.9 0.1 1.9e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EWM29175.1 - 2.4e-05 23.3 3.8 7.6e-05 21.7 0.0 2.7 3 0 0 3 3 3 1 Fungal protein kinase Yop-YscD_cpl PF16697.5 EWM29175.1 - 2.9e-05 24.3 0.1 0.00011 22.5 0.0 2.0 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain RIO1 PF01163.22 EWM29175.1 - 0.096 12.3 0.1 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.11 EWM29175.1 - 0.11 11.4 0.1 0.18 10.8 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Branch PF02485.21 EWM29176.1 - 0.0072 15.9 0.0 0.11 12.0 0.0 2.1 1 1 0 1 1 1 1 Core-2/I-Branching enzyme HA2 PF04408.23 EWM29177.1 - 1.1e-21 77.1 0.0 2e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EWM29177.1 - 8.1e-18 64.6 0.0 1.6e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EWM29177.1 - 9.6e-12 45.2 0.0 2e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EWM29177.1 - 4.3e-06 26.6 0.0 7.6e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EWM29177.1 - 2.7e-05 24.5 0.0 0.00019 21.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EWM29177.1 - 0.0056 16.4 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EWM29177.1 - 0.0057 17.2 0.0 0.02 15.4 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_19 PF13245.6 EWM29177.1 - 0.0095 16.3 0.0 0.02 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EWM29177.1 - 0.018 14.4 0.0 0.096 12.0 0.0 2.0 2 0 0 2 2 2 0 KaiC T2SSE PF00437.20 EWM29177.1 - 0.042 12.9 0.0 0.12 11.5 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 EWM29177.1 - 0.061 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 EWM29177.1 - 0.17 11.7 0.0 0.39 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRP54 PF00448.22 EWM29177.1 - 0.21 11.2 0.1 0.91 9.1 0.0 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF2895 PF11444.8 EWM29178.1 - 0.055 12.9 2.2 0.08 12.3 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2895) KASH_CCD PF14662.6 EWM29178.1 - 0.061 13.1 24.2 1.6 8.5 0.1 2.6 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF4407 PF14362.6 EWM29178.1 - 0.9 8.8 7.5 0.59 9.4 3.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) HTH_37 PF13744.6 EWM29178.1 - 2.1 8.4 7.8 0.12 12.4 1.5 2.2 3 0 0 3 3 3 0 Helix-turn-helix domain DUF1664 PF07889.12 EWM29178.1 - 3.2 7.8 12.7 0.66 10.0 3.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 EWM29178.1 - 3.3 6.7 19.9 0.34 10.0 15.4 1.5 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Prominin PF05478.11 EWM29178.1 - 6.1 4.7 6.1 12 3.8 0.0 2.1 2 0 0 2 2 2 0 Prominin MFS_1 PF07690.16 EWM29180.1 - 1.4e-08 34.0 39.7 1.4e-08 34.0 39.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 EWM29180.1 - 0.01 15.6 3.4 0.01 15.6 3.4 2.9 5 0 0 5 5 5 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) MFS_2 PF13347.6 EWM29180.1 - 0.02 13.5 31.8 0.14 10.7 10.9 3.7 2 2 0 2 2 2 0 MFS/sugar transport protein Myb_Cef PF11831.8 EWM29181.1 - 1e-40 139.8 0.0 1e-40 139.8 0.0 3.7 4 0 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 EWM29181.1 - 1.3e-20 73.3 4.6 1.8e-10 40.8 0.6 4.1 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EWM29181.1 - 1.3e-17 63.8 5.4 3e-12 46.6 2.4 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain TPT PF03151.16 EWM29182.1 - 1.9e-22 80.0 16.7 1.4e-13 50.9 1.6 2.0 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.11 EWM29182.1 - 0.00019 20.8 16.5 0.017 14.4 0.7 2.3 2 1 0 2 2 2 2 UAA transporter family EamA PF00892.20 EWM29182.1 - 0.00022 21.4 10.1 0.00022 21.4 10.1 2.7 2 1 0 2 2 2 1 EamA-like transporter family PUNUT PF16913.5 EWM29182.1 - 0.0015 17.8 15.6 0.0094 15.2 8.2 2.2 2 0 0 2 2 2 2 Purine nucleobase transmembrane transport C2 PF00168.30 EWM29183.1 - 0.001 19.3 0.0 0.002 18.4 0.0 1.4 1 0 0 1 1 1 1 C2 domain NIF PF03031.18 EWM29185.1 - 1.2e-48 164.9 0.1 2.3e-48 163.9 0.0 1.5 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase HAD PF12710.7 EWM29185.1 - 0.011 16.1 0.1 0.1 13.0 0.0 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Sld5 PF05916.11 EWM29187.1 - 2.3e-07 31.3 0.1 4e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 GINS complex protein FliT PF05400.13 EWM29187.1 - 0.0056 17.5 0.3 0.01 16.6 0.3 1.5 1 0 0 1 1 1 1 Flagellar protein FliT DUF842 PF05811.13 EWM29187.1 - 0.055 13.2 0.2 0.09 12.5 0.2 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) FOP_dimer PF09398.10 EWM29188.1 - 9.3e-05 22.6 0.0 0.00041 20.5 0.0 2.1 2 0 0 2 2 2 1 FOP N terminal dimerisation domain Patatin PF01734.22 EWM29189.1 - 1.6e-21 77.4 0.1 3.2e-21 76.4 0.1 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase cNMP_binding PF00027.29 EWM29189.1 - 7.1e-18 64.5 2.2 0.00032 20.7 0.0 6.5 7 0 0 7 7 7 3 Cyclic nucleotide-binding domain ATP12 PF07542.11 EWM29190.1 - 1e-29 103.2 0.0 1.8e-29 102.4 0.0 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein Asparaginase PF00710.20 EWM29191.1 - 1.8e-58 197.3 0.0 5.4e-58 195.7 0.0 1.7 2 0 0 2 2 2 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EWM29191.1 - 8.2e-23 80.8 0.2 1.3e-22 80.2 0.2 1.3 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Peptidase_M20 PF01546.28 EWM29192.1 - 2.9e-26 92.5 0.0 5.9e-26 91.5 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EWM29192.1 - 1.7e-15 56.8 0.0 3.3e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain PALP PF00291.25 EWM29194.1 - 2.8e-66 223.9 2.7 3.2e-66 223.7 2.7 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PAP_fibrillin PF04755.12 EWM29195.1 - 2.8e-05 24.2 0.0 0.029 14.3 0.0 2.3 2 0 0 2 2 2 2 PAP_fibrillin Pkinase PF00069.25 EWM29196.1 - 1.5e-69 234.3 0.0 1.9e-69 234.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM29196.1 - 1.1e-32 113.4 0.0 1.6e-32 112.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH_8 PF15409.6 EWM29196.1 - 0.00035 20.8 0.1 0.00076 19.7 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EWM29196.1 - 0.0032 17.9 0.0 0.0058 17.1 0.0 1.4 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 EWM29196.1 - 0.007 15.7 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EWM29196.1 - 0.0099 15.3 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EWM29196.1 - 0.035 14.0 0.0 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EWM29196.1 - 0.043 12.8 0.1 0.075 12.0 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain CbiX PF01903.17 EWM29197.1 - 1.7e-24 86.2 0.0 3.4e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 CbiX DUF4633 PF15464.6 EWM29197.1 - 0.0096 16.1 0.3 0.017 15.2 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4633) Androgen_recep PF02166.16 EWM29197.1 - 0.019 13.9 0.0 0.023 13.6 0.0 1.1 1 0 0 1 1 1 0 Androgen receptor Antimicrobial12 PF08107.11 EWM29197.1 - 0.092 12.5 0.8 0.17 11.6 0.8 1.4 1 0 0 1 1 1 0 Pleurocidin family CbiK PF06180.11 EWM29197.1 - 0.12 11.7 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) MMR_HSR1 PF01926.23 EWM29198.1 - 1.4e-10 41.2 0.1 3.2e-10 40.1 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EWM29198.1 - 0.0002 21.0 0.2 0.45 10.0 0.0 2.4 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EWM29198.1 - 0.0098 15.8 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase Roc PF08477.13 EWM29198.1 - 0.065 13.5 0.0 3.9 7.7 0.1 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase potato_inhibit PF00280.18 EWM29198.1 - 0.12 13.0 0.0 0.29 11.8 0.0 1.6 1 0 0 1 1 1 0 Potato inhibitor I family Spore_IV_A PF09547.10 EWM29198.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) Dynamin_N PF00350.23 EWM29198.1 - 0.15 12.1 4.7 1 9.4 0.0 3.4 3 0 0 3 3 3 0 Dynamin family FeoB_N PF02421.18 EWM29198.1 - 0.21 11.1 0.3 0.65 9.5 0.1 1.9 2 1 0 2 2 2 0 Ferrous iron transport protein B ATP_bind_1 PF03029.17 EWM29198.1 - 0.23 11.2 0.1 4.3 7.0 0.0 2.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Pkinase PF00069.25 EWM29199.1 - 6.3e-60 202.8 0.0 7.6e-60 202.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM29199.1 - 8.2e-47 159.7 0.0 1.2e-46 159.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EWM29199.1 - 0.0003 19.7 0.0 0.0004 19.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EWM29199.1 - 0.012 14.9 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 EWM29199.1 - 0.051 12.9 0.1 0.089 12.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EWM29199.1 - 0.06 12.3 0.0 0.29 10.0 0.0 1.9 1 1 0 1 1 1 0 Haspin like kinase domain SOR_SNZ PF01680.17 EWM29199.1 - 0.16 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 SOR/SNZ family Abhydrolase_5 PF12695.7 EWM29200.1 - 0.033 14.0 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Palm_thioest PF02089.15 EWM29200.1 - 0.18 11.6 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 EWM29201.1 - 0.02 14.6 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 EWM29201.1 - 0.039 13.7 0.0 0.066 13.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 EWM29201.1 - 0.077 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Hydrolase_4 PF12146.8 EWM29201.1 - 0.12 11.6 0.0 0.42 9.8 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Orn_Arg_deC_N PF02784.16 EWM29202.1 - 6.4e-30 104.3 0.0 9.2e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EWM29202.1 - 1.4e-17 63.7 0.0 1.9e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain PAP2_C PF14360.6 EWM29203.1 - 4.1e-16 59.3 2.0 9.4e-16 58.1 2.0 1.7 1 0 0 1 1 1 1 PAP2 superfamily C-terminal PAP2 PF01569.21 EWM29203.1 - 6.8e-08 32.4 1.2 6.8e-08 32.4 1.2 2.6 4 0 0 4 4 4 1 PAP2 superfamily PAP2_3 PF14378.6 EWM29203.1 - 0.0046 16.7 8.2 0.012 15.3 8.2 1.7 1 0 0 1 1 1 1 PAP2 superfamily Mito_carr PF00153.27 EWM29204.1 - 1.8e-57 191.3 4.5 3.1e-16 59.1 0.1 4.3 4 1 0 4 4 4 4 Mitochondrial carrier protein HIT PF01230.23 EWM29205.1 - 1.9e-28 99.0 0.0 4.1e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EWM29205.1 - 3.3e-22 79.1 0.0 5.4e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 EWM29206.1 - 1e-28 99.9 0.0 2.2e-28 98.9 0.0 1.5 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 EWM29206.1 - 4.2e-22 78.8 0.0 7.7e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF2613 PF11021.8 EWM29207.1 - 0.015 15.4 0.2 0.015 15.4 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) K_channel_TID PF07941.11 EWM29207.1 - 0.023 15.1 10.9 0.051 14.0 10.9 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain G0-G1_switch_2 PF15103.6 EWM29207.1 - 0.036 14.5 0.4 0.073 13.5 0.2 1.6 1 1 1 2 2 2 0 G0/G1 switch protein 2 LapA_dom PF06305.11 EWM29207.1 - 0.068 13.0 0.1 0.69 9.8 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF3318 PF11780.8 EWM29207.1 - 0.07 13.1 0.3 0.07 13.1 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3318) DUF4064 PF13273.6 EWM29207.1 - 0.084 13.1 0.4 0.34 11.2 0.0 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) MRI PF15325.6 EWM29207.1 - 0.2 12.7 1.2 0.28 12.3 0.4 1.6 2 0 0 2 2 2 0 Modulator of retrovirus infection Peptidase_C97 PF05903.14 EWM29208.1 - 2.5e-20 72.8 0.0 3.6e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain Peptidase_C97 PF05903.14 EWM29209.1 - 2.9e-28 98.6 0.0 3.8e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain PIP5K PF01504.18 EWM29210.1 - 5.1e-61 206.3 0.0 8.7e-61 205.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase CbiG_C PF01890.16 EWM29210.1 - 0.1 13.2 0.2 0.51 10.9 0.2 2.1 2 0 0 2 2 2 0 Cobalamin synthesis G C-terminus DEAD PF00270.29 EWM29212.1 - 1.2e-50 171.7 0.0 1.8e-50 171.1 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EWM29212.1 - 9.5e-31 106.4 0.0 3.5e-30 104.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EWM29212.1 - 6e-05 23.1 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EWM29212.1 - 7.9e-05 22.0 0.0 0.00012 21.4 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 EWM29212.1 - 0.042 14.1 0.8 0.11 12.8 0.1 2.0 2 1 0 2 2 2 0 AAA domain SWI2_SNF2 PF18766.1 EWM29212.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase NDK PF00334.19 EWM29213.1 - 1.7e-42 144.6 0.0 1.9e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.18 EWM29213.1 - 0.13 12.8 0.0 0.2 12.2 0.0 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ GTPase_binding PF09027.10 EWM29215.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 GTPase binding Kinesin PF00225.23 EWM29216.1 - 1.5e-98 329.8 0.0 8.1e-98 327.4 0.0 2.2 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EWM29216.1 - 3.7e-19 69.1 0.0 1.3e-18 67.4 0.0 2.0 1 0 0 1 1 1 1 Microtubule binding Syntaxin-6_N PF09177.11 EWM29217.1 - 1.8e-18 66.9 0.8 2.7e-18 66.3 0.8 1.3 1 0 0 1 1 1 1 Syntaxin 6, N-terminal DUF4208 PF13907.6 EWM29217.1 - 0.009 16.4 0.4 0.015 15.8 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) Acyltransferase PF01553.21 EWM29218.1 - 2.7e-27 95.0 0.0 5.1e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DUF374 PF04028.13 EWM29218.1 - 0.043 13.4 0.0 0.098 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF374) DUF4750 PF15938.5 EWM29218.1 - 0.098 12.3 1.4 0.19 11.4 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4750) CHCH PF06747.13 EWM29219.1 - 0.12 12.6 1.7 0.18 12.0 0.5 2.0 2 0 0 2 2 2 0 CHCH domain CX9C PF16860.5 EWM29219.1 - 0.88 9.6 4.1 1.5 8.9 0.3 2.5 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, GDA1_CD39 PF01150.17 EWM29220.1 - 8.5e-82 275.1 0.0 1.2e-81 274.6 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF2809 PF10990.8 EWM29220.1 - 0.11 13.2 0.1 0.23 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2809) PRIMA1 PF16101.5 EWM29220.1 - 0.16 12.0 3.6 0.35 10.9 3.6 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 EWM29220.1 - 2.2 7.7 6.3 3.8 6.9 6.3 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DEC-1_N PF04625.13 EWM29220.1 - 8.5 5.3 7.0 23 3.8 0.0 2.1 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Acyl_transf_1 PF00698.21 EWM29221.1 - 8.2e-61 206.2 0.0 1.5e-60 205.4 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.26 EWM29221.1 - 2.1e-41 142.2 0.0 4.9e-41 141.0 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EWM29221.1 - 3.3e-41 141.2 0.1 1.4e-39 135.9 0.0 2.9 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.12 EWM29221.1 - 2.6e-30 105.4 0.0 6.3e-30 104.2 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.22 EWM29221.1 - 1.5e-26 92.7 0.0 4.3e-26 91.2 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 EWM29221.1 - 2.6e-18 66.3 0.0 1.3e-17 64.0 0.0 2.1 1 1 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N PF00107.26 EWM29221.1 - 2.8e-17 62.9 1.8 1.2e-16 60.9 0.1 3.0 4 0 0 4 4 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EWM29221.1 - 2e-14 54.8 0.2 1.8e-13 51.7 0.0 3.0 3 0 0 3 3 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EWM29221.1 - 1e-13 51.2 0.1 4.5e-12 45.8 0.0 3.0 2 0 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.21 EWM29221.1 - 1.6e-10 40.9 0.0 3.7e-06 26.6 0.0 2.6 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family KAsynt_C_assoc PF16197.5 EWM29221.1 - 2.5e-09 37.6 0.0 7.7e-09 36.0 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 EWM29221.1 - 1.1e-06 28.9 0.1 2.7e-06 27.6 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.15 EWM29221.1 - 9.9e-06 24.9 0.0 0.016 14.4 0.0 2.6 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein ADH_N PF08240.12 EWM29221.1 - 1.8e-05 24.5 0.0 5.5e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain GDP_Man_Dehyd PF16363.5 EWM29221.1 - 3.8e-05 23.2 0.0 0.27 10.6 0.0 2.5 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Thiolase_N PF00108.23 EWM29221.1 - 0.00097 18.6 0.1 0.003 17.0 0.1 1.8 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 EWM29221.1 - 0.096 12.6 0.2 0.32 10.9 0.2 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ScsC_N PF18312.1 EWM29221.1 - 0.15 11.9 0.2 0.48 10.3 0.2 1.9 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain Sde2_N_Ubi PF13019.6 EWM29221.1 - 0.17 11.7 0.0 0.72 9.7 0.0 2.0 2 0 0 2 2 2 0 Silencing defective 2 N-terminal ubiquitin domain NmrA PF05368.13 EWM29221.1 - 0.19 11.3 1.2 1.8 8.0 0.0 2.8 3 0 0 3 3 3 0 NmrA-like family PseudoU_synth_2 PF00849.22 EWM29222.1 - 6.9e-28 97.8 0.0 1.2e-27 97.0 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase TruB_N PF01509.18 EWM29222.1 - 0.14 12.5 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 TruB family pseudouridylate synthase (N terminal domain) zf-RING_2 PF13639.6 EWM29223.1 - 2.3e-11 43.8 8.7 2.3e-11 43.8 8.7 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EWM29223.1 - 1.7e-07 30.9 17.9 3.2e-07 30.1 8.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EWM29223.1 - 2.1e-07 30.5 6.0 2.1e-07 30.5 6.0 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 EWM29223.1 - 3.5e-07 30.4 5.0 3.5e-07 30.4 5.0 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EWM29223.1 - 5.3e-07 29.4 16.3 1.2e-05 25.1 7.6 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EWM29223.1 - 4.1e-05 23.4 17.2 0.00012 21.9 7.2 2.3 2 0 0 2 2 2 2 zinc-RING finger domain Zn_ribbon_17 PF17120.5 EWM29223.1 - 0.00018 21.1 5.5 0.00018 21.1 5.5 2.2 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-ribbon_3 PF13248.6 EWM29223.1 - 0.00092 18.5 5.0 0.0051 16.2 1.7 2.4 2 0 0 2 2 2 1 zinc-ribbon domain zf-RING_UBOX PF13445.6 EWM29223.1 - 0.001 19.1 9.7 0.0063 16.5 5.2 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EWM29223.1 - 0.0011 18.8 8.5 0.0011 18.8 8.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EWM29223.1 - 0.002 18.2 2.0 0.002 18.2 2.0 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.7 EWM29223.1 - 0.0065 16.5 8.7 0.038 14.0 0.9 2.5 2 0 0 2 2 2 1 Double zinc ribbon PA PF02225.22 EWM29223.1 - 0.012 15.6 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 PA domain zf-C3H2C3 PF17122.5 EWM29223.1 - 0.019 15.0 1.7 0.019 15.0 1.7 2.6 2 1 0 2 2 2 0 Zinc-finger zinc_ribbon_2 PF13240.6 EWM29223.1 - 0.023 14.4 4.6 0.23 11.2 1.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Zn-C2H2_12 PF18112.1 EWM29223.1 - 0.14 12.6 3.4 0.41 11.2 0.2 2.6 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Prok-RING_4 PF14447.6 EWM29223.1 - 0.33 10.8 16.8 0.41 10.5 6.9 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.6 EWM29223.1 - 1.1 9.3 14.8 2.1 8.3 1.7 3.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zinc_ribbon_16 PF17034.5 EWM29223.1 - 1.1 9.4 6.8 0.12 12.6 1.4 2.0 2 0 0 2 2 2 0 Zinc-ribbon like family zinc_ribbon_15 PF17032.5 EWM29223.1 - 2.7 8.8 10.9 0.69 10.7 1.5 2.4 2 0 0 2 2 2 0 zinc-ribbon family Zn-ribbon_8 PF09723.10 EWM29223.1 - 2.8 8.1 8.6 5.1 7.3 1.3 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2_4 PF13894.6 EWM29223.1 - 3.2 8.8 8.7 17 6.6 0.0 4.0 3 1 1 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EWM29223.1 - 3.8 8.2 6.2 29 5.4 0.4 3.1 3 0 0 3 3 2 0 Zinc finger, C2H2 type HypA PF01155.19 EWM29223.1 - 8.1 6.5 8.6 1.1 9.3 0.6 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_4 PF14570.6 EWM29223.1 - 9.5 6.1 16.1 4 7.3 7.4 2.8 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain ANTH PF07651.16 EWM29224.1 - 1.6e-05 24.1 0.3 0.00096 18.2 0.2 3.0 2 1 0 2 2 2 1 ANTH domain YqfD PF06898.11 EWM29224.1 - 0.83 8.4 6.1 1.2 7.9 6.1 1.2 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD TFIIA PF03153.13 EWM29224.1 - 4.2 7.2 20.1 0.05 13.6 12.7 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CPSF100_C PF13299.6 EWM29224.1 - 4.7 7.4 9.4 9.8 6.3 9.4 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal OAD_gamma PF04277.13 EWM29224.1 - 5.1 7.8 6.3 1.5e+02 3.0 0.0 2.5 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Cwf_Cwc_15 PF04889.12 EWM29224.1 - 6.7 6.4 30.7 0.32 10.7 18.9 2.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Lipoprotein_2 PF00921.17 EWM29225.1 - 0.041 13.4 0.6 0.041 13.4 0.6 2.0 1 1 0 2 2 2 0 Borrelia lipoprotein S1 PF00575.23 EWM29226.1 - 2e-13 50.5 1.8 5.2e-13 49.1 1.8 1.8 1 0 0 1 1 1 1 S1 RNA binding domain zf-CCHC_3 PF13917.6 EWM29226.1 - 0.00015 21.7 0.6 0.0011 18.9 0.0 2.6 2 0 0 2 2 2 1 Zinc knuckle RNA_pol_Rpc4 PF05132.14 EWM29226.1 - 0.17 12.3 4.4 0.42 11.0 4.4 1.8 1 0 0 1 1 1 0 RNA polymerase III RPC4 ETF PF01012.21 EWM29227.1 - 3.7e-36 124.7 9.1 5.5e-36 124.1 9.1 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 EWM29227.1 - 1.3e-35 121.3 1.9 3.6e-34 116.6 0.2 2.4 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain PreAtp-grasp PF18604.1 EWM29227.1 - 0.046 13.4 0.1 2.8 7.6 0.0 2.4 2 0 0 2 2 2 0 Pre ATP-grasp domain TPP_enzyme_M PF00205.22 EWM29227.1 - 0.23 11.2 2.0 0.27 11.0 0.2 2.0 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain PA28_beta PF02252.18 EWM29228.1 - 1.4e-17 63.7 0.0 2.7e-12 46.6 0.0 2.4 2 0 0 2 2 2 2 Proteasome activator pa28 beta subunit Methyltransf_23 PF13489.6 EWM29229.1 - 2e-14 53.8 0.0 3.1e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EWM29229.1 - 2e-11 44.5 0.0 3.3e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM29229.1 - 5.9e-09 36.5 0.0 1.3e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM29229.1 - 3e-08 34.2 0.0 5.5e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EWM29229.1 - 0.00021 20.9 0.0 0.0004 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 EWM29229.1 - 0.00051 19.4 0.0 0.0013 18.1 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 EWM29229.1 - 0.0011 18.7 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EWM29229.1 - 0.0015 18.0 0.0 0.003 17.0 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.18 EWM29229.1 - 0.0032 16.8 0.0 0.0051 16.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EWM29229.1 - 0.065 12.4 0.0 0.11 11.6 0.0 1.4 1 1 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_24 PF13578.6 EWM29229.1 - 0.11 13.5 0.0 0.24 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Zn_clus PF00172.18 EWM29230.1 - 0.00019 21.5 9.2 0.00019 21.5 9.2 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ARS2 PF04959.13 EWM29231.1 - 1.3e-12 48.5 0.0 2.5e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Arsenite-resistance protein 2 DUF4187 PF13821.6 EWM29231.1 - 0.016 14.9 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) zf-C2H2 PF00096.26 EWM29231.1 - 0.04 14.4 0.3 0.088 13.3 0.3 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF3564 PF12087.8 EWM29231.1 - 0.13 12.2 0.4 0.26 11.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3564) ELFV_dehydrog PF00208.21 EWM29232.1 - 4.6e-30 105.1 0.0 7.8e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 EWM29232.1 - 2.4e-21 75.1 0.0 3.7e-18 64.6 0.0 2.7 2 1 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 EWM29232.1 - 0.11 12.3 0.1 0.35 10.8 0.0 1.8 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain SHMT PF00464.19 EWM29233.1 - 2.9e-173 576.1 0.0 3.6e-173 575.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 EWM29233.1 - 0.016 14.5 0.0 0.048 12.9 0.0 1.7 1 1 0 1 1 1 0 Beta-eliminating lyase TolA_bind_tri PF16331.5 EWM29233.1 - 0.17 12.0 0.2 2.4 8.3 0.0 2.3 2 0 0 2 2 2 0 TolA binding protein trimerisation RNA_pol_3_Rpc31 PF11705.8 EWM29235.1 - 0.017 15.4 24.3 0.02 15.1 24.3 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 EWM29235.1 - 0.018 14.4 16.3 0.021 14.1 16.3 1.1 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 EWM29235.1 - 0.064 12.8 20.5 0.067 12.8 20.5 1.1 1 0 0 1 1 1 0 PPP4R2 Pox_Ag35 PF03286.14 EWM29235.1 - 0.18 11.5 18.6 0.031 14.1 15.4 1.5 2 0 0 2 2 2 0 Pox virus Ag35 surface protein UPF0565 PF10561.9 EWM29235.1 - 0.2 10.9 2.6 0.24 10.5 2.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 DDHD PF02862.17 EWM29235.1 - 0.58 10.3 6.6 0.68 10.1 6.6 1.1 1 0 0 1 1 1 0 DDHD domain DUF913 PF06025.12 EWM29235.1 - 0.61 9.0 8.4 0.66 8.9 8.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Nop14 PF04147.12 EWM29235.1 - 0.78 7.9 25.8 0.85 7.8 25.8 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4746 PF15928.5 EWM29235.1 - 0.9 8.9 23.4 0.94 8.8 23.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF3684 PF12449.8 EWM29235.1 - 1.1 6.9 11.1 1.3 6.7 11.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3684) BSP_II PF05432.11 EWM29235.1 - 1.8 8.2 29.2 3.4 7.3 29.2 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Zip PF02535.22 EWM29235.1 - 2.5 7.2 5.8 2.4 7.3 5.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 EWM29235.1 - 2.6 6.7 11.1 2.7 6.7 11.1 1.1 1 0 0 1 1 1 0 Presenilin EIIBC-GUT_N PF03612.14 EWM29235.1 - 3.1 7.5 9.4 5.1 6.8 9.4 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Serinc PF03348.15 EWM29235.1 - 3.1 6.6 5.9 2.7 6.8 5.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) FYDLN_acid PF09538.10 EWM29235.1 - 5.6 7.7 20.4 1.3 9.7 17.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) RNA_polI_A34 PF08208.11 EWM29235.1 - 5.9 6.9 21.0 9 6.3 21.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Nop53 PF07767.11 EWM29235.1 - 5.9 6.2 31.9 8 5.7 31.9 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Neur_chan_memb PF02932.16 EWM29235.1 - 6.4 6.8 6.5 8.3 6.4 6.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hist_deacetyl PF00850.19 EWM29235.1 - 7.2 6.0 6.1 7.6 5.9 6.1 1.1 1 0 0 1 1 1 0 Histone deacetylase domain RPA43_OB PF17875.1 EWM29235.1 - 7.9 7.1 11.5 12 6.5 11.5 1.5 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Glucokinase PF02685.16 EWM29239.1 - 8.8e-66 222.1 0.0 1.9e-65 221.0 0.0 1.5 2 0 0 2 2 2 1 Glucokinase DUF563 PF04577.14 EWM29240.1 - 3.7e-19 69.7 0.0 6e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) PRK PF00485.18 EWM29242.1 - 0.0025 17.6 0.0 0.37 10.5 0.0 2.1 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family cobW PF02492.19 EWM29242.1 - 0.038 13.6 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.14 EWM29242.1 - 0.073 12.3 0.0 0.092 12.0 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain MIB_HERC2 PF06701.13 EWM29244.1 - 1.1e-10 41.6 4.4 2.8e-10 40.3 4.4 1.7 1 0 0 1 1 1 1 Mib_herc2 zf-Nse PF11789.8 EWM29244.1 - 1.1e-05 25.1 0.2 2.6e-05 23.9 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SPRY PF00622.28 EWM29244.1 - 0.0015 18.6 0.0 0.0037 17.4 0.0 1.6 1 0 0 1 1 1 1 SPRY domain U-box PF04564.15 EWM29244.1 - 0.012 15.8 0.0 0.036 14.2 0.0 1.9 1 0 0 1 1 1 0 U-box domain zf-C3HC4_4 PF15227.6 EWM29244.1 - 0.018 15.2 1.7 0.053 13.7 1.7 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EWM29244.1 - 0.023 14.7 0.4 0.023 14.7 0.4 2.7 2 1 1 3 3 3 0 RING-type zinc-finger zf-RING_2 PF13639.6 EWM29244.1 - 0.026 14.9 1.0 0.1 13.0 1.0 2.1 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.6 EWM29244.1 - 0.37 10.7 4.0 0.15 11.9 0.3 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EWM29244.1 - 0.51 10.7 1.8 0.56 10.5 0.1 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EWM29244.1 - 0.94 9.4 2.5 1.8 8.5 0.6 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Glycolytic PF00274.19 EWM29245.1 - 9.4e-139 462.0 0.0 1.2e-138 461.6 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I MOSC_N PF03476.16 EWM29247.1 - 1.3e-31 108.9 0.0 2.5e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 EWM29247.1 - 3e-27 95.2 0.0 6.8e-27 94.1 0.0 1.6 1 0 0 1 1 1 1 MOSC domain Peptidase_M24 PF00557.24 EWM29247.1 - 3.7e-24 85.6 0.1 6.2e-24 84.8 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3772 PF12607.8 EWM29248.1 - 0.042 13.6 0.3 9.8 6.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) PsbP PF01789.16 EWM29249.1 - 5.9e-19 68.7 0.0 8.6e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 PsbP Beach PF02138.18 EWM29252.1 - 4.4e-117 390.4 0.0 6.3e-117 389.9 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 EWM29252.1 - 1.2e-07 32.2 1.2 0.053 14.4 0.0 4.2 3 0 0 3 3 3 2 WD domain, G-beta repeat PH_BEACH PF14844.6 EWM29252.1 - 1.2e-06 28.5 0.1 3.1e-06 27.2 0.1 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH PNRC PF15365.6 EWM29252.1 - 3.6 7.5 7.1 15 5.5 7.1 2.2 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator motif UBA_4 PF14555.6 EWM29254.1 - 5.6e-09 35.7 0.0 9.2e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain Acetyltransf_13 PF13880.6 EWM29255.1 - 3.9e-22 78.0 0.2 8.4e-22 76.9 0.2 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 EWM29255.1 - 2.4e-13 49.6 0.4 2.4e-13 49.6 0.4 1.8 2 0 0 2 2 2 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.7 EWM29255.1 - 0.0022 18.4 0.1 0.0079 16.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EWM29255.1 - 0.013 15.8 0.1 0.1 12.9 0.1 2.2 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family DUF3877 PF12993.7 EWM29255.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) DUF4724 PF15852.5 EWM29256.1 - 5.4 7.6 6.7 15 6.2 0.2 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4724) TLC PF03219.14 EWM29257.1 - 2.3e-196 653.3 15.8 2.8e-196 653.0 15.8 1.0 1 0 0 1 1 1 1 TLC ATP/ADP transporter Mito_carr PF00153.27 EWM29258.1 - 7.9e-47 157.1 4.7 4.3e-15 55.4 0.1 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein CDC45 PF02724.14 EWM29260.1 - 0.0029 16.0 21.3 0.005 15.2 21.3 1.4 1 0 0 1 1 1 1 CDC45-like protein SpoIIP PF07454.11 EWM29260.1 - 0.71 9.3 23.2 2.5 7.5 23.2 2.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) ABC2_membrane_2 PF12679.7 EWM29260.1 - 0.96 8.7 2.0 1.2 8.3 2.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein CobT PF06213.12 EWM29260.1 - 1.6 8.1 37.1 3.3 7.0 37.1 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT ETF_QO PF05187.13 EWM29262.1 - 2.1e-25 88.9 0.0 4.2e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S FAD_binding_2 PF00890.24 EWM29262.1 - 1.9e-07 30.5 1.5 0.00085 18.5 1.3 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EWM29262.1 - 2.4e-07 30.9 0.0 7.3e-06 26.1 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EWM29262.1 - 1.3e-06 27.8 0.0 0.00012 21.4 0.0 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 EWM29262.1 - 8.3e-06 25.6 0.1 0.019 14.5 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EWM29262.1 - 0.00016 20.5 0.3 0.00048 18.9 0.3 1.7 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 EWM29262.1 - 0.0003 19.9 0.1 0.001 18.2 0.2 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EWM29262.1 - 0.00056 19.2 0.0 0.00075 18.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EWM29262.1 - 0.00082 18.7 0.3 0.0013 18.0 0.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EWM29262.1 - 0.0078 16.2 0.1 0.016 15.2 0.1 1.6 1 1 0 1 1 1 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 EWM29262.1 - 0.015 14.4 0.0 0.036 13.2 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 EWM29262.1 - 0.05 12.9 0.0 0.082 12.1 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 EWM29262.1 - 0.13 11.6 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 EWM29262.1 - 0.16 12.5 0.1 21 5.8 0.2 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Hydrolase PF00702.26 EWM29263.1 - 7.3e-07 29.7 0.1 5.3e-05 23.6 0.1 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EWM29263.1 - 2.7e-06 27.4 0.0 0.045 13.9 0.0 2.5 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EWM29263.1 - 3.6e-06 27.2 0.0 0.0024 18.0 0.0 2.6 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HAD PF12710.7 EWM29263.1 - 0.00064 20.2 0.2 0.0023 18.3 0.2 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DZR PF12773.7 EWM29263.1 - 0.0013 18.7 2.0 0.0041 17.1 2.0 1.8 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 EWM29263.1 - 0.0036 17.0 4.0 0.02 14.6 2.5 2.8 2 1 1 3 3 3 2 zinc-ribbon domain DHHC PF01529.20 EWM29263.1 - 0.038 14.1 0.5 0.064 13.4 0.5 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase UPF0547 PF10571.9 EWM29263.1 - 0.047 13.8 3.5 0.11 12.6 3.5 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 AAA_31 PF13614.6 EWM29264.1 - 2.6e-20 73.1 0.0 5e-20 72.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 EWM29264.1 - 9.7e-19 67.7 0.0 1.4e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 EWM29264.1 - 5.2e-14 52.3 0.5 9.2e-13 48.2 0.5 2.5 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase MipZ PF09140.11 EWM29264.1 - 8.2e-10 38.4 0.1 1.3e-09 37.7 0.1 1.4 1 1 0 1 1 1 1 ATPase MipZ CBP_BcsQ PF06564.12 EWM29264.1 - 5.4e-07 29.3 0.0 1.3e-06 28.1 0.0 1.6 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ ArsA_ATPase PF02374.15 EWM29264.1 - 8.5e-07 28.4 1.3 2e-06 27.2 1.3 1.5 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_24 PF13479.6 EWM29264.1 - 6.7e-05 22.7 0.0 9.8e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 EWM29264.1 - 0.00038 20.0 0.0 0.022 14.2 0.2 2.2 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MeaB PF03308.16 EWM29264.1 - 0.057 12.4 0.1 0.087 11.8 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 EWM29264.1 - 0.083 12.5 1.9 0.38 10.4 1.2 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain CLP1_P PF16575.5 EWM29264.1 - 0.099 12.4 0.1 0.24 11.2 0.1 1.6 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_25 PF13481.6 EWM29264.1 - 0.51 9.9 1.7 0.8 9.2 0.8 1.7 2 0 0 2 2 2 0 AAA domain Peptidase_C2 PF00648.21 EWM29265.1 - 9.1e-36 123.4 0.0 2.3e-35 122.1 0.0 1.6 1 1 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 EWM29265.1 - 6.1e-19 68.7 0.0 0.00032 21.0 0.0 4.8 4 1 0 4 4 4 4 Calpain large subunit, domain III MIT PF04212.18 EWM29265.1 - 7e-05 22.8 0.1 0.44 10.6 0.0 2.5 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain A_deaminase PF00962.22 EWM29266.1 - 2.3e-107 359.1 0.0 6e-107 357.8 0.0 1.6 1 1 0 1 1 1 1 Adenosine/AMP deaminase NCE101 PF11654.8 EWM29267.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Non-classical export protein 1 Glyco_transf_15 PF01793.16 EWM29268.1 - 3.1e-83 279.7 0.1 2.5e-48 165.0 0.5 2.8 2 1 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase Methyltransf_22 PF13383.6 EWM29268.1 - 6.9e-27 94.6 0.1 3.4e-26 92.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain DUF4185 PF13810.6 EWM29268.1 - 8.4e-09 35.1 0.3 5.1e-08 32.5 0.3 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4185) Methyltransf_21 PF05050.12 EWM29268.1 - 2.6e-06 27.6 0.0 6.1e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase FkbM domain RhoGAP PF00620.27 EWM29269.1 - 1.9e-25 89.5 0.0 2.9e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain ESSS PF10183.9 EWM29270.1 - 0.00045 20.4 0.1 0.00075 19.7 0.1 1.4 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Unstab_antitox PF09720.10 EWM29270.1 - 0.0034 17.4 1.4 0.0034 17.4 1.4 1.8 2 0 0 2 2 2 1 Putative addiction module component mit_SMPDase PF14724.6 EWM29271.1 - 6.8e-05 21.1 2.5 0.023 12.7 0.6 3.0 4 0 0 4 4 4 2 Mitochondrial-associated sphingomyelin phosphodiesterase NYD-SP28_assoc PF14775.6 EWM29272.1 - 2.4e-06 27.5 0.9 2.4e-06 27.5 0.9 4.2 4 0 0 4 4 4 1 Sperm tail C-terminal domain NleF_casp_inhib PF16809.5 EWM29272.1 - 0.41 10.6 6.0 0.16 11.9 0.7 2.5 2 1 0 2 2 2 0 NleF caspase inhibitor DUF5093 PF17011.5 EWM29272.1 - 0.84 9.9 6.6 0.1 12.9 0.9 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF5093) OmpH PF03938.14 EWM29272.1 - 3.6 7.9 35.3 0.25 11.7 13.5 3.2 1 1 1 3 3 3 0 Outer membrane protein (OmpH-like) SelK_SelG PF10961.8 EWM29273.1 - 5.4e-10 39.8 6.5 8.7e-10 39.1 6.5 1.4 1 1 0 1 1 1 1 Selenoprotein SelK_SelG FoP_duplication PF13865.6 EWM29273.1 - 8.3 7.0 8.8 12 6.5 8.8 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 SufE PF02657.15 EWM29274.1 - 1.6e-32 112.0 0.0 3e-32 111.0 0.0 1.5 1 0 0 1 1 1 1 Fe-S metabolism associated domain BolA PF01722.18 EWM29274.1 - 1.2e-26 92.8 0.0 2.6e-26 91.7 0.0 1.6 1 0 0 1 1 1 1 BolA-like protein GCFC PF07842.12 EWM29276.1 - 1e-15 58.1 0.0 5.4e-13 49.2 0.0 2.6 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein GCFC PF07842.12 EWM29277.1 - 4.5e-16 59.3 0.0 7.1e-13 48.8 0.0 2.7 1 1 1 2 2 2 2 GC-rich sequence DNA-binding factor-like protein DUF948 PF06103.11 EWM29277.1 - 0.18 12.1 0.2 3.9 7.8 0.0 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) GatB_N PF02934.15 EWM29278.1 - 1.9e-79 266.9 0.0 2.3e-79 266.6 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 EWM29278.1 - 2.8e-38 131.1 0.0 4.1e-38 130.6 0.0 1.3 1 0 0 1 1 1 1 GatB domain Acyl-CoA_dh_C PF12806.7 EWM29278.1 - 0.1 12.8 0.2 4.2 7.6 0.3 2.5 2 0 0 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like Tim17 PF02466.19 EWM29279.1 - 7.4e-28 97.2 4.2 7.4e-28 97.2 4.2 1.6 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family NUC173 PF08161.12 EWM29281.1 - 2.6e-39 135.0 0.5 6.2e-36 124.0 0.0 4.6 4 1 0 4 4 4 1 NUC173 domain Adaptin_N PF01602.20 EWM29281.1 - 0.00018 20.2 2.8 0.2 10.2 0.1 3.3 3 0 0 3 3 3 2 Adaptin N terminal region HEAT PF02985.22 EWM29281.1 - 0.024 14.9 15.5 9.5 6.8 0.1 8.0 8 0 0 8 8 8 0 HEAT repeat IPTL-CTERM PF18203.1 EWM29281.1 - 0.087 12.7 0.7 0.5 10.3 0.1 2.7 2 0 0 2 2 2 0 IPTL-CTERM motif HEAT_2 PF13646.6 EWM29281.1 - 0.088 13.2 13.8 0.67 10.4 0.4 6.1 5 1 2 7 7 7 0 HEAT repeats HSP70 PF00012.20 EWM29282.1 - 3.7e-61 207.1 0.0 1.1e-60 205.5 0.0 1.7 2 0 0 2 2 2 1 Hsp70 protein Pkinase PF00069.25 EWM29283.1 - 4.5e-71 239.3 0.8 5.6e-71 239.0 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM29283.1 - 9.1e-41 139.9 0.0 1.5e-40 139.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 EWM29283.1 - 3.5e-14 53.0 0.4 3.2e-09 37.1 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EWM29283.1 - 9.4e-12 43.6 1.2 5.9e-06 25.5 0.2 3.9 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 EWM29283.1 - 1.4e-09 37.1 0.4 0.047 13.6 0.1 3.8 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 EWM29283.1 - 4.8e-09 35.9 0.2 6.1e-05 22.8 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EWM29283.1 - 1.8e-05 24.0 0.3 0.16 11.6 0.0 2.8 3 0 0 3 3 3 2 EF hand Kdo PF06293.14 EWM29283.1 - 0.00015 21.2 0.7 0.00033 20.1 0.7 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EWM29283.1 - 0.0003 19.7 0.1 0.00075 18.4 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EWM29283.1 - 0.001 18.4 0.1 1 8.6 0.1 2.5 1 1 1 2 2 2 2 Kinase-like SPARC_Ca_bdg PF10591.9 EWM29283.1 - 0.002 18.5 0.2 0.0063 16.8 0.2 1.9 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region APH PF01636.23 EWM29283.1 - 0.0053 16.7 0.1 0.011 15.7 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 EWM29283.1 - 0.018 14.7 0.4 0.14 11.8 0.0 2.5 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 EF-hand_4 PF12763.7 EWM29283.1 - 0.072 13.0 0.2 0.17 11.8 0.2 1.6 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand YrbL-PhoP_reg PF10707.9 EWM29283.1 - 0.081 12.4 0.0 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Dockerin_1 PF00404.18 EWM29283.1 - 0.16 12.2 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 Dockerin type I domain E1-E2_ATPase PF00122.20 EWM29284.1 - 0.054 13.0 2.1 1.3 8.5 0.0 2.6 2 0 0 2 2 2 0 E1-E2 ATPase Synaptobrevin PF00957.21 EWM29285.1 - 7.7e-15 54.5 0.2 1.2e-14 53.8 0.2 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EWM29285.1 - 4.2e-09 36.3 0.0 6.9e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain MIS13 PF08202.11 EWM29285.1 - 0.054 12.8 0.4 0.077 12.3 0.4 1.1 1 0 0 1 1 1 0 Mis12-Mtw1 protein family Nsp1_C PF05064.13 EWM29285.1 - 0.091 12.6 0.3 0.27 11.1 0.1 1.9 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF1084 PF06454.11 EWM29286.1 - 2.5e-09 36.9 7.8 9.1e-09 35.1 7.8 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) DUF2070 PF09843.9 EWM29286.1 - 1.4 7.1 9.6 0.99 7.6 7.2 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) UMPH-1 PF05822.12 EWM29287.1 - 1.3e-25 90.3 0.0 1.7e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) DUF2854 PF11016.8 EWM29288.1 - 9.1e-43 145.7 0.0 1.3e-42 145.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2854) MacB_PCD PF12704.7 EWM29288.1 - 0.026 14.9 0.2 0.091 13.1 0.1 1.9 1 1 1 2 2 2 0 MacB-like periplasmic core domain DUF2854 PF11016.8 EWM29289.1 - 4.3e-09 36.4 0.0 7.1e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2854) CRT-like PF08627.10 EWM29290.1 - 9.7e-67 225.3 6.7 1.2e-66 225.0 6.7 1.1 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 EWM29290.1 - 8.9e-07 29.2 9.9 8.9e-07 29.2 9.9 3.2 2 1 1 3 3 3 1 EamA-like transporter family SLC35F PF06027.12 EWM29290.1 - 0.00011 21.9 6.1 0.0019 17.8 6.0 2.1 1 1 0 1 1 1 1 Solute carrier family 35 UAA PF08449.11 EWM29290.1 - 0.011 15.0 3.7 0.021 14.0 3.6 1.6 1 1 0 1 1 1 0 UAA transporter family TMEM208_SND2 PF05620.11 EWM29290.1 - 0.31 10.8 2.3 0.92 9.3 0.1 2.7 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Acetyltransf_1 PF00583.25 EWM29291.1 - 7.9e-33 113.2 0.2 3.9e-17 62.6 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EWM29291.1 - 2.5e-17 63.1 0.1 1.9e-09 37.8 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 EWM29291.1 - 1e-14 54.3 0.0 4.4e-06 26.6 0.0 2.3 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_10 PF13673.7 EWM29291.1 - 9.2e-14 51.5 0.0 4.8e-08 33.0 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EWM29291.1 - 1.2e-10 41.6 0.0 0.00036 20.6 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EWM29291.1 - 9.9e-09 35.5 0.0 0.0031 17.7 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EWM29291.1 - 1.4e-08 35.5 0.0 0.0022 18.7 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EWM29291.1 - 1.7e-08 34.2 0.0 0.00087 19.0 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain DUF5594 PF18057.1 EWM29291.1 - 0.0039 17.0 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF5594) Acetyltransf_CG PF14542.6 EWM29291.1 - 0.03 14.4 0.0 10 6.3 0.0 2.4 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase PPE PF00823.19 EWM29291.1 - 0.12 12.5 2.2 0.21 11.7 2.2 1.2 1 0 0 1 1 1 0 PPE family FAD_binding_1 PF00667.20 EWM29292.1 - 2.5e-53 180.9 0.0 3.8e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EWM29292.1 - 4.2e-34 117.8 0.3 7.3e-34 117.0 0.3 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EWM29292.1 - 1e-15 58.3 0.0 2.1e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.20 EWM29293.1 - 1.9e-53 181.3 0.0 3e-53 180.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EWM29293.1 - 3.5e-25 88.9 0.1 6.6e-25 88.0 0.1 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EWM29293.1 - 9.3e-16 58.4 0.0 1.8e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain MMgT PF10270.9 EWM29294.1 - 0.043 14.2 0.0 0.068 13.5 0.0 1.3 1 1 0 1 1 1 0 Membrane magnesium transporter zf-C3HC4_3 PF13920.6 EWM29295.1 - 1.9e-10 40.5 7.9 3.2e-10 39.7 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SH3_3 PF08239.11 EWM29295.1 - 9.5e-06 25.8 0.5 0.0088 16.3 0.1 2.6 2 1 0 2 2 2 2 Bacterial SH3 domain Nuc_N PF14448.6 EWM29295.1 - 0.013 15.3 0.1 1.8 8.5 0.0 2.6 2 0 0 2 2 2 0 Nuclease N terminal zf-RING_5 PF14634.6 EWM29295.1 - 0.05 13.6 9.0 0.11 12.5 9.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 EWM29295.1 - 0.64 10.4 10.5 1.1 9.6 10.5 1.4 1 0 0 1 1 1 0 Ring finger domain zf-P11 PF03854.14 EWM29295.1 - 0.72 9.6 4.5 1.6 8.5 4.5 1.6 1 0 0 1 1 1 0 P-11 zinc finger TRM13 PF05206.14 EWM29297.1 - 1.7e-54 185.1 0.0 1.5e-53 182.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase TRM13 zf-U11-48K PF05253.12 EWM29297.1 - 9.5e-09 35.0 0.5 9.5e-09 35.0 0.5 2.3 2 0 0 2 2 2 1 U11-48K-like CHHC zinc finger zf-TRM13_CCCH PF11722.8 EWM29297.1 - 1.5e-07 31.0 1.2 3.1e-07 30.0 1.2 1.6 1 0 0 1 1 1 1 CCCH zinc finger in TRM13 protein MTS PF05175.14 EWM29297.1 - 0.047 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain SpoU_methylase PF00588.19 EWM29298.1 - 2.3e-21 76.4 0.0 4.7e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 SpoU rRNA Methylase family Proteasome PF00227.26 EWM29299.1 - 2.8e-28 98.7 0.0 3.9e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit EF-hand_5 PF13202.6 EWM29300.1 - 8.9e-10 37.6 0.9 0.00041 19.7 0.6 2.5 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 EWM29300.1 - 1.5e-09 36.7 0.4 0.00011 21.5 0.4 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EWM29300.1 - 1e-08 34.4 0.3 0.0066 16.3 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EWM29300.1 - 1.2e-06 28.9 0.1 2.6e-06 27.8 0.1 1.6 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EWM29300.1 - 9.7e-05 22.1 0.2 0.46 10.4 0.4 2.4 2 0 0 2 2 2 2 EF-hand domain pair EMP24_GP25L PF01105.24 EWM29303.1 - 2e-29 102.8 0.0 3e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD 2TM PF13239.6 EWM29303.1 - 0.048 14.0 0.1 4.2 7.7 0.0 2.2 2 0 0 2 2 2 0 2TM domain TFIIB PF00382.19 EWM29304.1 - 1e-10 41.5 0.0 1.9e-05 24.6 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EWM29304.1 - 0.00014 21.3 1.1 0.00052 19.5 0.1 2.2 2 0 0 2 2 2 1 TFIIB zinc-binding Arteri_Gl PF00951.18 EWM29305.1 - 0.012 15.4 0.0 0.016 15.0 0.0 1.1 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein PCRF PF03462.18 EWM29306.1 - 4.9e-66 222.3 0.3 7.9e-66 221.6 0.3 1.3 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 EWM29306.1 - 3.9e-35 120.3 0.8 3.9e-35 120.3 0.8 1.7 2 0 0 2 2 2 1 RF-1 domain YtfJ_HI0045 PF09695.10 EWM29306.1 - 0.055 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (YtfJ_HI0045) ABC_tran_CTD PF16326.5 EWM29306.1 - 0.087 13.1 8.8 0.38 11.0 0.1 3.0 3 0 0 3 3 3 0 ABC transporter C-terminal domain KH_1 PF00013.29 EWM29308.1 - 8.5e-62 204.9 15.4 2.6e-17 62.4 0.7 4.6 5 0 0 5 5 5 4 KH domain KH_2 PF07650.17 EWM29308.1 - 9.2e-12 44.6 8.7 0.0072 16.1 0.1 4.3 4 0 0 4 4 4 3 KH domain KH_4 PF13083.6 EWM29308.1 - 2.5e-09 36.9 6.4 0.0075 16.1 0.1 3.7 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 EWM29308.1 - 7.9e-07 29.1 2.0 1.2 9.3 0.1 4.1 4 0 0 4 4 4 3 NusA-like KH domain TFIIA PF03153.13 EWM29308.1 - 4.1 7.3 32.0 9 6.2 32.0 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 EWM29308.1 - 8.1 4.6 22.8 11 4.1 22.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ABC1 PF03109.16 EWM29309.1 - 7.2e-17 61.7 0.0 2.3e-16 60.0 0.0 1.9 2 0 0 2 2 2 1 ABC1 family Pkinase PF00069.25 EWM29309.1 - 0.00047 19.6 0.0 0.004 16.6 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain RIO1 PF01163.22 EWM29309.1 - 0.023 14.3 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EWM29309.1 - 0.25 11.2 4.9 1.4 8.8 4.9 2.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family zf-RING_2 PF13639.6 EWM29312.1 - 4.6e-11 42.9 12.5 4.6e-11 42.9 12.5 3.4 3 1 0 3 3 3 1 Ring finger domain zf-RING_11 PF17123.5 EWM29312.1 - 1.7e-10 40.5 4.7 5.8e-10 38.7 4.7 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 EWM29312.1 - 1e-05 25.7 7.8 1e-05 25.7 7.8 2.4 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EWM29312.1 - 7.8e-05 22.6 7.3 0.00011 22.2 5.4 2.3 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EWM29312.1 - 8.8e-05 22.3 11.3 8.8e-05 22.3 11.3 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EWM29312.1 - 0.003 17.1 8.6 0.003 17.1 8.6 2.8 3 1 0 3 3 3 1 Zinc-ribbon, C4HC2 type BRCA-2_OB1 PF09103.10 EWM29313.1 - 2.1e-29 102.0 0.0 4.7e-29 100.8 0.0 1.7 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 EWM29313.1 - 4.5e-14 52.5 0.3 9e-13 48.3 0.0 2.5 2 1 0 2 2 2 1 BRCA2, helical Mpp10 PF04006.12 EWM29314.1 - 1.2e-90 304.8 22.4 1.4e-90 304.6 22.4 1.0 1 0 0 1 1 1 1 Mpp10 protein BSP_II PF05432.11 EWM29314.1 - 1.3 8.7 28.4 3.4 7.3 28.4 1.7 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) ubiquitin PF00240.23 EWM29315.1 - 5.9e-07 29.1 0.0 9.1e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Ist1 PF03398.14 EWM29316.1 - 2.3e-56 190.2 6.8 2.7e-56 190.0 6.8 1.0 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Ribosomal_L29e PF01779.17 EWM29317.1 - 1.2e-20 73.5 9.5 1.2e-20 73.5 9.5 1.7 2 0 0 2 2 2 1 Ribosomal L29e protein family GNT-I PF03071.15 EWM29317.1 - 0.032 13.0 0.1 0.036 12.8 0.1 1.1 1 0 0 1 1 1 0 GNT-I family C2 PF00168.30 EWM29317.1 - 0.048 13.9 0.0 0.076 13.3 0.0 1.5 1 1 0 1 1 1 0 C2 domain NAD_binding_10 PF13460.6 EWM29318.1 - 1.6e-18 67.3 1.1 4.3e-12 46.3 0.6 2.3 2 0 0 2 2 2 2 NAD(P)H-binding NmrA PF05368.13 EWM29318.1 - 5.6e-13 49.0 0.2 8.9e-13 48.3 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EWM29318.1 - 1.5e-07 31.1 0.2 4.7e-07 29.5 0.1 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EWM29318.1 - 6e-06 25.5 0.1 8.5e-06 25.0 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 EWM29318.1 - 0.00017 21.1 0.0 0.00039 19.9 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 EWM29318.1 - 0.0035 16.8 0.2 0.0054 16.2 0.2 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase CIA30 PF08547.12 EWM29318.1 - 0.0045 17.0 0.0 0.0093 16.0 0.0 1.5 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) KR PF08659.10 EWM29318.1 - 0.0057 16.6 0.2 0.016 15.2 0.2 1.8 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.18 EWM29318.1 - 0.099 12.9 0.1 0.21 11.9 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Serinc PF03348.15 EWM29319.1 - 0.046 12.7 0.0 0.046 12.7 0.0 1.8 2 0 0 2 2 2 0 Serine incorporator (Serinc) DUF3169 PF11368.8 EWM29319.1 - 2.5 7.5 0.0 2.5 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Trm112p PF03966.16 EWM29320.1 - 1.9e-16 60.4 0.0 2.6e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Trm112p-like protein DUF2939 PF11159.8 EWM29320.1 - 0.18 12.2 0.0 0.33 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) Bac_rhamnosid6H PF17389.2 EWM29321.1 - 3.5e-87 292.8 0.0 4.8e-87 292.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 EWM29321.1 - 1.4e-32 112.9 0.0 9.9e-32 110.1 0.0 2.1 1 1 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 EWM29321.1 - 2.3e-20 72.5 0.0 4.8e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 EWM29321.1 - 0.004 16.9 0.0 0.015 15.1 0.0 2.0 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain ERCC4 PF02732.15 EWM29322.1 - 1.8e-17 64.0 0.0 5.6e-17 62.4 0.0 1.8 1 1 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 EWM29322.1 - 4.7e-05 23.7 0.0 0.00013 22.2 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain SmpB PF01668.18 EWM29323.1 - 9.9e-46 155.2 0.2 1.2e-45 154.9 0.2 1.1 1 0 0 1 1 1 1 SmpB protein DUF4017 PF13209.6 EWM29323.1 - 0.11 12.5 0.3 0.25 11.3 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4017) PHD_2 PF13831.6 EWM29323.1 - 9.6 5.9 8.3 8.6 6.0 0.4 2.6 2 0 0 2 2 2 0 PHD-finger FKBP_C PF00254.28 EWM29325.1 - 7.5e-15 55.0 0.0 1.4e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Mesd PF10185.9 EWM29326.1 - 7.9e-09 35.6 0.5 1e-08 35.3 0.5 1.1 1 0 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor DUF2299 PF10061.9 EWM29326.1 - 0.024 14.4 0.0 0.046 13.5 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2299) LPAM_1 PF08139.12 EWM29326.1 - 1.5 9.5 5.0 2.6 8.7 5.0 1.4 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site BTB PF00651.31 EWM29327.1 - 9.9e-22 77.3 0.1 2.2e-21 76.2 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 EWM29327.1 - 3.9e-07 30.1 0.0 5e-06 26.5 0.0 2.4 1 1 0 1 1 1 1 BTB And C-terminal Kelch RPN13_C PF16550.5 EWM29328.1 - 1.1e-25 90.0 2.9 2.1e-25 89.1 2.9 1.5 1 0 0 1 1 1 1 UCH-binding domain Proteasom_Rpn13 PF04683.13 EWM29328.1 - 1.5e-22 79.9 0.1 2.2e-22 79.4 0.1 1.2 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Ribosomal_S11 PF00411.19 EWM29329.1 - 8.4e-47 158.1 0.9 1.1e-46 157.8 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 EWM29329.1 - 0.044 14.0 0.0 0.086 13.1 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) BKACE PF05853.12 EWM29329.1 - 0.09 12.1 0.2 0.12 11.7 0.2 1.2 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme E1_dh PF00676.20 EWM29330.1 - 1.3e-98 329.7 0.1 3.9e-98 328.1 0.0 1.8 2 0 0 2 2 2 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 EWM29330.1 - 0.0026 17.0 0.0 0.0056 15.9 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase HSF_DNA-bind PF00447.17 EWM29331.1 - 4.2e-30 104.2 0.0 6.1e-30 103.7 0.0 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding FlaC_arch PF05377.11 EWM29331.1 - 0.01 16.2 0.8 0.02 15.3 0.8 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) LPP PF04728.13 EWM29331.1 - 0.031 14.7 0.2 0.13 12.6 0.1 2.0 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Med3 PF11593.8 EWM29331.1 - 0.059 12.6 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal FAM176 PF14851.6 EWM29331.1 - 0.062 13.0 0.3 0.15 11.8 0.3 1.6 1 0 0 1 1 1 0 FAM176 family DivIC PF04977.15 EWM29331.1 - 0.086 12.6 0.2 0.18 11.6 0.2 1.4 1 0 0 1 1 1 0 Septum formation initiator Med9 PF07544.13 EWM29331.1 - 0.12 12.4 0.2 0.24 11.5 0.2 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Myc_N PF01056.18 EWM29331.1 - 0.24 11.2 1.0 0.35 10.7 1.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF4407 PF14362.6 EWM29331.1 - 1.5 8.1 4.6 2.2 7.6 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mpp10 PF04006.12 EWM29332.1 - 1.7e-19 69.8 6.6 1.9e-19 69.6 6.6 1.0 1 0 0 1 1 1 1 Mpp10 protein Paf1 PF03985.13 EWM29332.1 - 0.71 8.8 13.9 0.82 8.6 13.9 1.1 1 0 0 1 1 1 0 Paf1 DUF4746 PF15928.5 EWM29332.1 - 1.7 8.0 13.7 2.2 7.7 13.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CDC45 PF02724.14 EWM29332.1 - 6.3 5.0 12.4 7.3 4.7 12.4 1.1 1 0 0 1 1 1 0 CDC45-like protein IGPS PF00218.21 EWM29333.1 - 7.6e-14 51.5 0.0 1.2e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase FIST PF08495.10 EWM29333.1 - 0.00036 20.6 0.3 0.0017 18.4 0.1 2.2 3 0 0 3 3 3 1 FIST N domain TMP-TENI PF02581.17 EWM29333.1 - 0.015 14.7 0.0 0.041 13.2 0.0 1.7 1 0 0 1 1 1 0 Thiamine monophosphate synthase UCH PF00443.29 EWM29334.1 - 1.3e-25 90.3 0.0 1.9e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EWM29334.1 - 2.3e-13 50.3 1.3 4e-13 49.5 1.3 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EWM29334.1 - 2.5e-05 24.1 0.0 0.015 14.9 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 EWM29334.1 - 0.064 13.0 1.1 0.19 11.5 1.1 1.7 1 0 0 1 1 1 0 Variant UBP zinc finger PD40 PF07676.12 EWM29335.1 - 2.1e-06 27.5 0.2 0.0014 18.5 0.1 4.4 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat RVT_N PF13655.6 EWM29335.1 - 0.0038 17.5 0.0 0.83 10.0 0.0 2.5 2 0 0 2 2 2 2 N-terminal domain of reverse transcriptase DPPIV_N PF00930.21 EWM29335.1 - 0.0082 14.9 0.0 0.1 11.3 0.0 2.6 2 1 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region SIR2 PF02146.17 EWM29337.1 - 5.2e-41 140.5 0.0 7.1e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 EWM29337.1 - 0.036 13.8 0.0 0.51 10.1 0.0 2.5 2 1 1 3 3 3 0 Thiamine pyrophosphate enzyme, central domain UDPGT PF00201.18 EWM29338.1 - 3e-08 32.9 0.1 9.1e-06 24.7 0.0 2.2 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.20 EWM29338.1 - 0.087 12.9 0.0 0.54 10.3 0.0 2.1 2 0 0 2 2 2 0 Glycosyltransferase family 28 N-terminal domain GDI PF00996.18 EWM29339.1 - 6.3e-36 123.8 0.0 1.4e-20 73.3 0.0 3.7 2 1 0 2 2 2 2 GDP dissociation inhibitor CPBP PF02517.16 EWM29340.1 - 3.1e-17 62.7 4.4 3.1e-17 62.7 4.4 2.0 2 0 0 2 2 2 1 CPBP intramembrane metalloprotease CAP_GLY PF01302.25 EWM29341.1 - 2.4e-16 59.5 0.0 5.6e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 EWM29341.1 - 4.8e-12 45.9 6.0 0.0014 19.0 0.1 4.4 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EWM29341.1 - 4e-06 26.5 11.2 0.0037 17.0 0.1 4.4 3 2 1 4 4 4 2 Leucine rich repeat LRR_9 PF14580.6 EWM29341.1 - 2.6e-05 23.8 0.0 0.00071 19.1 0.0 2.4 2 0 0 2 2 2 1 Leucine-rich repeat DUF1028 PF06267.12 EWM29341.1 - 0.02 14.7 0.0 0.07 12.9 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF1028) Ubiquitin_2 PF14560.6 EWM29341.1 - 0.23 11.9 0.0 0.41 11.1 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain GFA PF04828.14 EWM29342.1 - 7e-07 29.5 1.2 7e-07 29.5 1.2 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme CoA_transf_3 PF02515.17 EWM29343.1 - 1.2e-131 439.2 0.0 1.4e-131 439.0 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III DUF1992 PF09350.10 EWM29344.1 - 1.4e-13 50.8 0.2 3.5e-13 49.5 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) TLC PF03219.14 EWM29345.1 - 1.1e-151 506.0 18.8 1.5e-151 505.5 18.8 1.1 1 0 0 1 1 1 1 TLC ATP/ADP transporter Myb_DNA-binding PF00249.31 EWM29346.1 - 0.001 19.2 0.2 0.0056 16.8 0.1 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain CIA30 PF08547.12 EWM29347.1 - 5.7e-32 110.9 0.0 8.6e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) NAD_binding_10 PF13460.6 EWM29347.1 - 1.5e-27 96.7 0.0 1.3e-14 54.5 0.0 2.2 2 0 0 2 2 2 2 NAD(P)H-binding NmrA PF05368.13 EWM29347.1 - 1.4e-08 34.5 0.0 3.5e-06 26.7 0.0 2.4 2 0 0 2 2 2 2 NmrA-like family Epimerase PF01370.21 EWM29347.1 - 3.1e-08 33.4 0.0 9.5e-08 31.8 0.0 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EWM29347.1 - 6.4e-07 29.0 0.2 1.1e-06 28.3 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase CBM_11 PF03425.13 EWM29347.1 - 2.1e-05 24.5 0.0 3.4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain (family 11) GDP_Man_Dehyd PF16363.5 EWM29347.1 - 0.00027 20.5 0.0 0.00052 19.5 0.0 1.4 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EWM29347.1 - 0.0008 18.6 0.0 0.025 13.7 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain KR PF08659.10 EWM29347.1 - 0.0021 18.0 0.2 0.0035 17.3 0.2 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 EWM29347.1 - 0.0023 17.1 0.4 0.36 10.0 0.4 2.4 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 EWM29347.1 - 0.013 14.6 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EWM29347.1 - 0.024 13.6 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding PF00501.28 EWM29348.1 - 2.3e-93 313.1 0.1 2.8e-93 312.8 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EWM29348.1 - 1.6e-25 89.9 0.9 2.6e-24 86.0 0.3 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EWM29348.1 - 4.9e-15 55.2 1.0 1.2e-14 54.0 1.0 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus TPR_1 PF00515.28 EWM29349.1 - 0.00025 20.7 0.1 0.00075 19.2 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EWM29349.1 - 0.0023 17.6 0.0 0.006 16.2 0.0 1.7 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.17 EWM29349.1 - 0.0035 17.3 0.4 0.012 15.7 0.1 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat 2Fe-2S_thioredx PF01257.19 EWM29349.1 - 0.014 15.2 0.1 0.11 12.4 0.1 2.3 1 1 1 2 2 2 0 Thioredoxin-like [2Fe-2S] ferredoxin TPR_7 PF13176.6 EWM29349.1 - 0.022 14.8 0.0 0.053 13.6 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 EWM29349.1 - 0.065 13.5 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TTL PF03133.15 EWM29350.1 - 5e-22 78.4 0.0 2e-11 43.5 0.0 3.1 3 0 0 3 3 3 3 Tubulin-tyrosine ligase family Zn_clus PF00172.18 EWM29352.1 - 8.7e-08 32.2 10.9 1.5e-07 31.4 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CRS1_YhbY PF01985.21 EWM29353.1 - 8.3e-07 29.1 1.1 2e-06 27.9 1.1 1.7 1 1 0 1 1 1 1 CRS1 / YhbY (CRM) domain Redoxin PF08534.10 EWM29355.1 - 1.3e-22 80.1 0.0 1.6e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EWM29355.1 - 2.1e-06 27.7 0.0 2.7e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Prefoldin_2 PF01920.20 EWM29355.1 - 0.29 11.1 0.0 0.44 10.5 0.0 1.2 1 0 0 1 1 1 0 Prefoldin subunit Aldose_epim PF01263.20 EWM29356.1 - 2.2e-75 253.8 0.0 6.5e-75 252.2 0.0 1.6 1 1 0 1 1 1 1 Aldose 1-epimerase S4 PF01479.25 EWM29356.1 - 0.031 14.0 0.0 0.07 12.9 0.0 1.6 1 0 0 1 1 1 0 S4 domain Bromodomain PF00439.25 EWM29357.1 - 1.6e-20 72.9 0.0 2.8e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 EWM29357.1 - 1.4e-10 41.2 0.1 2.3e-10 40.5 0.1 1.4 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Nop16 PF09420.10 EWM29357.1 - 0.061 13.4 0.7 0.084 12.9 0.7 1.2 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 Ofd1_CTDD PF10637.9 EWM29358.1 - 2.1e-60 204.2 0.0 6e-56 189.6 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 EWM29358.1 - 1.5e-24 86.4 0.0 3.1e-24 85.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 EWM29358.1 - 9.1e-15 55.3 0.0 1.5e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PDZ_6 PF17820.1 EWM29359.1 - 2.8e-07 30.3 0.1 5.4e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EWM29359.1 - 6.5e-06 26.4 0.0 1.4e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EWM29359.1 - 0.0018 18.6 0.0 0.0062 16.8 0.0 1.9 2 0 0 2 2 2 1 PDZ domain XPA_C PF05181.12 EWM29360.1 - 2e-11 43.7 0.0 3.7e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 EWM29360.1 - 0.00088 19.3 0.2 0.0014 18.6 0.2 1.3 1 0 0 1 1 1 1 XPA protein N-terminal CALM_bind PF16025.5 EWM29360.1 - 0.052 14.0 7.6 0.11 13.0 7.6 1.6 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding zf-RING_10 PF16685.5 EWM29360.1 - 0.11 12.6 0.4 0.28 11.4 0.4 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 ADD_DNMT3 PF17980.1 EWM29360.1 - 0.14 12.1 0.3 0.28 11.2 0.3 1.4 1 0 0 1 1 1 0 Cysteine rich ADD domain in DNMT3 TMEM247 PF15444.6 EWM29360.1 - 0.48 10.4 2.2 1.1 9.2 2.2 1.6 1 0 0 1 1 1 0 Transmembrane protein 247 Abhydrolase_1 PF00561.20 EWM29361.1 - 2.2e-06 27.5 0.2 1e-05 25.3 0.1 2.1 2 1 1 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EWM29361.1 - 0.00031 21.4 3.8 0.05 14.2 1.4 2.8 2 1 1 3 3 3 2 Alpha/beta hydrolase family DLH PF01738.18 EWM29361.1 - 0.008 15.7 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 EWM29361.1 - 0.013 14.7 0.0 0.053 12.8 0.0 1.8 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 EWM29361.1 - 0.015 15.0 0.0 0.032 14.0 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family WD40 PF00400.32 EWM29362.1 - 7.7e-36 121.5 20.4 5.4e-05 23.9 0.0 9.2 9 0 0 9 9 9 7 WD domain, G-beta repeat DENN PF02141.21 EWM29362.1 - 7e-15 55.5 0.4 1.5e-14 54.4 0.4 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 EWM29362.1 - 3.1e-06 27.1 0.7 3.1e-06 27.1 0.7 2.1 2 0 0 2 2 2 1 dDENN domain Nup160 PF11715.8 EWM29362.1 - 0.0063 15.2 4.4 0.25 10.0 0.5 3.3 2 1 2 4 4 4 2 Nucleoporin Nup120/160 RCC1 PF00415.18 EWM29363.1 - 2.4e-53 178.6 26.6 3.9e-10 40.2 0.4 7.9 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EWM29363.1 - 2.4e-29 100.5 36.4 9.1e-06 25.3 0.6 7.4 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat DUF4213 PF13938.6 EWM29363.1 - 0.00011 22.3 1.3 9.5 6.5 0.1 4.2 4 0 0 4 4 4 3 Putative heavy-metal chelation Hira PF07569.11 EWM29363.1 - 0.084 12.6 0.5 1 9.0 0.1 2.6 3 0 0 3 3 3 0 TUP1-like enhancer of split Zincin_1 PF06262.11 EWM29364.1 - 0.1 12.7 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Zincin-like metallopeptidase LSM PF01423.22 EWM29365.1 - 3.1e-15 55.6 0.1 4.1e-15 55.2 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EWM29365.1 - 0.00059 19.9 0.3 0.0012 18.9 0.1 1.6 2 0 0 2 2 2 1 Ataxin 2 SM domain DKCLD PF08068.12 EWM29366.1 - 1.8e-32 111.2 0.1 1.8e-31 108.0 0.2 2.3 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 EWM29366.1 - 1.7e-21 77.2 0.5 2e-18 67.2 0.5 3.3 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 EWM29366.1 - 2.4e-21 75.4 3.1 7.8e-21 73.8 3.1 2.0 1 0 0 1 1 1 1 PUA domain TruB_C_2 PF16198.5 EWM29366.1 - 1.3e-19 70.0 0.6 2.5e-19 69.2 0.6 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain UPF0113 PF03657.13 EWM29366.1 - 0.027 14.7 0.0 0.069 13.4 0.0 1.7 1 0 0 1 1 1 0 UPF0113 PUA domain RNA_polI_A34 PF08208.11 EWM29366.1 - 2.9 7.9 32.0 5.1 7.1 32.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 His_Phos_1 PF00300.22 EWM29368.1 - 8.4e-17 61.5 0.5 8.4e-17 61.5 0.5 2.0 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) DAO PF01266.24 EWM29369.1 - 4.9e-63 213.8 2.7 6.3e-63 213.5 2.7 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EWM29369.1 - 2.9e-11 43.1 3.9 1.1e-10 41.2 3.9 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EWM29369.1 - 3.4e-08 33.1 0.0 3.3e-06 26.6 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EWM29369.1 - 3.4e-07 29.8 0.7 5.3e-07 29.2 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EWM29369.1 - 8.4e-06 25.1 0.2 0.00017 20.8 0.7 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EWM29369.1 - 8.5e-05 21.8 0.6 0.0042 16.2 0.3 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.7 EWM29369.1 - 0.00012 21.6 0.2 0.0002 20.9 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EWM29369.1 - 0.00012 22.3 0.5 0.00025 21.2 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 EWM29369.1 - 0.00017 22.0 0.0 0.0004 20.8 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding HI0933_like PF03486.14 EWM29369.1 - 0.00022 20.1 0.7 0.0051 15.6 1.3 2.0 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 EWM29369.1 - 0.00052 19.3 0.7 0.00095 18.5 0.7 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 EWM29369.1 - 0.0014 19.1 0.3 0.0029 18.1 0.3 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EWM29369.1 - 0.0019 17.5 0.0 0.0031 16.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EWM29369.1 - 0.01 15.1 0.5 0.019 14.2 0.5 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 EWM29369.1 - 0.018 13.9 0.6 3.8 6.2 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase TrkA_N PF02254.18 EWM29369.1 - 0.033 14.4 0.0 0.069 13.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.6 EWM29369.1 - 0.04 13.9 0.2 5.3 7.0 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 EWM29369.1 - 0.086 12.4 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 EWM29369.1 - 0.16 12.2 0.2 0.63 10.3 0.1 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DAGAT PF03982.13 EWM29372.1 - 5.5e-35 120.7 0.0 8.5e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase FKBP_C PF00254.28 EWM29373.1 - 1.3e-35 121.6 0.0 1.9e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Bac_rhamnosid PF05592.11 EWM29373.1 - 0.12 12.4 0.0 3.8 7.6 0.0 2.1 1 1 1 2 2 2 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain Pneumo_att_G PF05539.11 EWM29374.1 - 0.61 9.6 2.4 0.97 9.0 2.4 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Mpv17_PMP22 PF04117.12 EWM29375.1 - 9.3e-13 48.2 0.2 9.3e-13 48.2 0.2 2.6 3 0 0 3 3 3 1 Mpv17 / PMP22 family Acyl_transf_1 PF00698.21 EWM29376.1 - 3.6e-60 204.1 0.1 8.8e-60 202.9 0.0 1.7 2 0 0 2 2 1 1 Acyl transferase domain KR PF08659.10 EWM29376.1 - 3.6e-42 144.3 0.2 2.2e-40 138.5 0.0 3.1 3 0 0 3 3 3 1 KR domain ketoacyl-synt PF00109.26 EWM29376.1 - 5.9e-41 140.7 0.0 1.5e-40 139.4 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain NAD_binding_4 PF07993.12 EWM29376.1 - 1.9e-30 105.9 0.0 4.8e-30 104.6 0.0 1.8 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.22 EWM29376.1 - 1.2e-26 93.1 0.0 4.4e-26 91.2 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 EWM29376.1 - 1.1e-17 64.3 0.0 4.6e-17 62.2 0.0 2.0 1 1 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N PF00107.26 EWM29376.1 - 2.3e-17 63.2 0.2 1.2e-16 60.9 0.1 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 EWM29376.1 - 1.1e-14 54.4 0.0 5.8e-13 48.7 0.0 3.0 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 EWM29376.1 - 4.4e-14 53.7 0.0 2.2e-13 51.4 0.0 2.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 EWM29376.1 - 2.5e-11 43.5 0.2 4.1e-06 26.4 0.0 3.1 3 1 0 3 3 3 2 NAD dependent epimerase/dehydratase family KAsynt_C_assoc PF16197.5 EWM29376.1 - 7.7e-10 39.2 0.1 2.9e-09 37.4 0.0 2.1 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension ADH_N PF08240.12 EWM29376.1 - 1.2e-06 28.3 0.0 4.5e-06 26.5 0.0 2.0 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 EWM29376.1 - 1.9e-06 28.1 0.1 4.6e-06 26.9 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 EWM29376.1 - 2.5e-06 27.2 0.1 1.4e-05 24.8 0.0 2.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 EWM29376.1 - 0.00047 19.4 0.0 0.017 14.2 0.0 2.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EWM29376.1 - 0.00065 19.2 0.0 0.19 11.1 0.0 2.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Thiolase_N PF00108.23 EWM29376.1 - 0.0011 18.4 0.1 0.0031 16.9 0.1 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 EWM29376.1 - 0.12 12.3 0.2 0.32 10.9 0.2 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III RasGEF_N PF00618.20 EWM29376.1 - 0.14 12.4 0.0 0.49 10.6 0.0 1.9 1 0 0 1 1 1 0 RasGEF N-terminal motif NAD_binding_10 PF13460.6 EWM29376.1 - 1.8 8.4 4.6 4.4 7.2 0.5 3.3 2 1 0 2 2 2 0 NAD(P)H-binding Sigma70_ner PF04546.13 EWM29376.1 - 8.7 6.2 9.2 0.65 9.8 3.1 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region PQ-loop PF04193.14 EWM29377.1 - 1.2e-27 95.4 5.3 1.3e-13 50.5 0.6 3.0 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 EWM29377.1 - 0.043 14.6 7.8 0.031 15.1 5.2 2.1 1 1 0 1 1 1 0 ER lumen protein retaining receptor TMEM189_B_dmain PF10520.9 EWM29378.1 - 6e-59 199.0 0.7 8.9e-59 198.5 0.7 1.3 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain FA_hydroxylase PF04116.13 EWM29378.1 - 7.4e-05 23.1 3.2 0.0001 22.7 2.6 1.5 1 1 0 1 1 1 1 Fatty acid hydroxylase superfamily WD40 PF00400.32 EWM29379.1 - 3.7e-15 56.0 10.4 0.00019 22.1 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM29379.1 - 0.00039 20.7 0.4 1.5 9.2 0.0 4.0 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 EWM29379.1 - 0.15 10.0 0.0 0.23 9.4 0.0 1.2 1 0 0 1 1 1 0 IKI3 family tRNA-synt_1g PF09334.11 EWM29380.1 - 8.3e-94 314.5 0.1 2.1e-53 181.5 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EWM29380.1 - 8e-36 123.5 1.0 7.4e-20 70.7 0.1 3.6 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA_bind PF01588.20 EWM29380.1 - 9.7e-28 96.1 0.1 1.9e-27 95.2 0.1 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain tRNA-synt_1e PF01406.19 EWM29380.1 - 2.1e-12 47.0 0.0 1.6e-05 24.4 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 EWM29380.1 - 6.3e-07 28.6 0.0 0.0018 17.3 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (K) Anticodon_1 PF08264.13 EWM29380.1 - 0.0034 17.4 0.0 0.0074 16.3 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA RNase_II_C_S1 PF18614.1 EWM29380.1 - 0.31 11.0 2.1 0.61 10.1 0.4 2.4 2 0 0 2 2 2 0 RNase II-type exonuclease C-terminal S1 domain Mannosyl_trans3 PF11051.8 EWM29381.1 - 9.4e-21 74.4 0.0 2.5e-14 53.3 0.0 2.1 1 1 0 2 2 2 2 Mannosyltransferase putative Mpv17_PMP22 PF04117.12 EWM29382.1 - 1.1e-21 76.8 2.2 2.5e-21 75.7 2.2 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family Solute_trans_a PF03619.16 EWM29383.1 - 7.7e-82 274.8 15.6 1e-81 274.3 15.6 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha SRP54 PF00448.22 EWM29383.1 - 6.5e-66 221.7 0.0 1.6e-65 220.4 0.0 1.7 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 EWM29383.1 - 2.5e-05 24.6 0.0 5.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain SRP54_N PF02881.19 EWM29383.1 - 5.6e-05 23.3 2.4 0.00012 22.3 1.1 2.2 1 1 1 2 2 2 1 SRP54-type protein, helical bundle domain AAA_30 PF13604.6 EWM29383.1 - 0.00055 19.7 0.1 0.002 17.9 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EWM29383.1 - 0.00073 20.0 0.0 0.0023 18.3 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EWM29383.1 - 0.0026 18.1 0.0 0.0074 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EWM29383.1 - 0.0087 16.0 0.0 0.028 14.3 0.0 1.9 1 0 0 1 1 1 1 NACHT domain Zeta_toxin PF06414.12 EWM29383.1 - 0.012 15.0 0.9 0.022 14.0 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.6 EWM29383.1 - 0.037 13.7 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EWM29383.1 - 0.086 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_31 PF13614.6 EWM29383.1 - 0.11 12.4 0.4 3.1 7.7 0.2 2.3 1 1 1 2 2 2 0 AAA domain ATPase_2 PF01637.18 EWM29383.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Helicase_RecD PF05127.14 EWM29383.1 - 0.17 11.8 0.2 0.47 10.3 0.1 1.8 2 0 0 2 2 2 0 Helicase Phage_Coat_Gp8 PF05371.12 EWM29383.1 - 0.33 10.8 1.3 4.6 7.1 0.1 2.7 2 0 0 2 2 2 0 Phage major coat protein, Gp8 Metallophos PF00149.28 EWM29385.1 - 6.5e-32 111.7 0.1 8.5e-32 111.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MFS_1 PF07690.16 EWM29386.1 - 1.6e-11 43.7 34.4 3.6e-11 42.6 34.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily IFRD PF05004.13 EWM29387.1 - 2.3e-46 158.3 1.0 3.3e-46 157.8 1.0 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) TetR_C_33 PF13305.6 EWM29387.1 - 0.92 10.3 4.9 6.4 7.6 1.0 3.7 2 2 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Urb2 PF10441.9 EWM29388.1 - 1.2e-21 77.6 0.0 1.3e-20 74.2 0.0 2.8 4 0 0 4 4 4 1 Urb2/Npa2 family DUF2173 PF09941.9 EWM29388.1 - 0.12 12.7 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2173) Cas_Cas02710 PF09670.10 EWM29389.1 - 0.022 13.6 0.3 0.028 13.3 0.3 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) DUF5544 PF17698.1 EWM29389.1 - 0.056 13.6 0.4 0.092 12.9 0.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5544) Glyco_hydro81C PF17652.1 EWM29390.1 - 2.3e-94 316.5 1.9 3.1e-94 316.1 1.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 EWM29390.1 - 2.2e-39 135.5 0.0 3.2e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Exo_endo_phos PF03372.23 EWM29391.1 - 3.4e-05 23.5 0.0 0.0001 21.9 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2569 PF10754.9 EWM29391.1 - 0.82 10.1 13.8 0.35 11.3 8.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) 7tm_1 PF00001.21 EWM29391.1 - 1.2 8.4 9.7 2.5 7.3 9.7 1.5 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Thiolase_N PF00108.23 EWM29392.1 - 1.8e-81 273.3 0.1 2.9e-81 272.7 0.0 1.3 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EWM29392.1 - 3.1e-42 143.1 2.5 1.1e-41 141.4 2.2 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain SpoVAD PF07451.11 EWM29392.1 - 0.016 13.9 0.3 0.034 12.8 0.3 1.4 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) ketoacyl-synt PF00109.26 EWM29392.1 - 0.025 14.2 3.4 0.2 11.2 1.3 2.5 2 1 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EWM29392.1 - 0.13 12.2 1.2 16 5.5 0.2 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III N2227 PF07942.12 EWM29393.1 - 6.1e-37 127.3 0.0 2e-21 76.4 0.0 2.2 2 0 0 2 2 2 2 N2227-like protein Methyltransf_11 PF08241.12 EWM29393.1 - 7.2e-06 26.6 0.0 0.027 15.1 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EWM29393.1 - 0.0017 19.0 0.0 0.34 11.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM29393.1 - 0.0025 17.6 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 EWM29393.1 - 0.0044 17.7 0.0 1.4 9.7 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_29 PF03141.16 EWM29393.1 - 0.021 13.4 0.0 0.032 12.8 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_23 PF13489.6 EWM29393.1 - 0.03 14.2 0.0 0.057 13.3 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain C2 PF00168.30 EWM29394.1 - 2.9e-11 43.6 0.0 5.1e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 C2 domain DUF3275 PF11679.8 EWM29394.1 - 0.037 14.0 0.6 0.065 13.2 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3275) Herpes_gE PF02480.16 EWM29394.1 - 0.04 12.7 0.1 0.056 12.2 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E PGF-CTERM PF18204.1 EWM29394.1 - 2 8.5 7.3 5.5 7.1 5.1 2.4 2 0 0 2 2 2 0 PGF-CTERM motif Cation_efflux PF01545.21 EWM29396.1 - 1.3e-38 132.7 9.6 2.7e-38 131.7 9.6 1.6 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EWM29396.1 - 3.3e-23 81.6 0.6 4.9e-16 58.6 0.1 2.5 2 0 0 2 2 2 2 Dimerisation domain of Zinc Transporter ProRS-C_1 PF09180.11 EWM29397.1 - 7e-18 64.6 0.0 1.3e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 EWM29397.1 - 1.3e-17 64.4 0.0 2e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EWM29397.1 - 1.7e-16 60.2 0.0 3.2e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain WHEP-TRS PF00458.20 EWM29397.1 - 1.8e-11 44.0 0.0 3.4e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 WHEP-TRS domain CPSase_L_D2 PF02786.17 EWM29398.1 - 1.6e-103 344.7 0.1 2.9e-77 258.9 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 EWM29398.1 - 3e-49 166.1 0.0 5.9e-49 165.2 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 EWM29398.1 - 4e-42 144.1 0.0 8.7e-42 143.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 EWM29398.1 - 2.1e-36 125.0 0.0 4.9e-36 123.7 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain MGS PF02142.22 EWM29398.1 - 1.8e-15 56.9 0.0 4.4e-14 52.4 0.0 3.2 3 0 0 3 3 3 1 MGS-like domain Dala_Dala_lig_C PF07478.13 EWM29398.1 - 2.3e-13 50.1 0.5 2.2e-05 24.1 0.2 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EWM29398.1 - 3.5e-13 49.5 0.1 8.5e-08 32.0 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 EWM29398.1 - 6.2e-12 45.4 0.0 2.4e-05 24.1 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 EWM29398.1 - 2.4e-05 24.2 0.2 0.002 17.9 0.2 2.4 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.14 EWM29398.1 - 0.00038 20.5 0.1 1.1 9.3 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain B12-binding PF02310.19 EWM29398.1 - 0.019 15.0 0.0 2.9 8.0 0.0 3.7 4 0 0 4 4 4 0 B12 binding domain CoA_binding_2 PF13380.6 EWM29398.1 - 0.046 14.2 0.1 0.55 10.7 0.0 2.9 3 0 0 3 3 3 0 CoA binding domain Aldedh PF00171.22 EWM29399.1 - 2.2e-139 465.0 0.6 2.2e-139 465.0 0.6 1.5 2 0 0 2 2 2 1 Aldehyde dehydrogenase family Trp_ring PF18669.1 EWM29399.1 - 0.054 13.7 0.3 0.26 11.5 0.0 2.3 2 0 0 2 2 2 0 Trimeric autotransporter adhesin Trp ring domain BCIP PF13862.6 EWM29400.1 - 1.2e-24 87.2 0.0 4.5e-24 85.4 0.0 2.0 1 1 1 2 2 2 1 p21-C-terminal region-binding protein tRNA_Me_trans PF03054.16 EWM29401.1 - 2.6e-112 375.1 0.0 5.2e-112 374.1 0.0 1.5 1 1 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 EWM29401.1 - 6.6e-05 22.2 0.0 0.00022 20.4 0.0 1.8 2 0 0 2 2 2 1 NAD synthase ThiI PF02568.14 EWM29401.1 - 0.00012 21.8 0.0 0.00019 21.1 0.0 1.2 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 EWM29401.1 - 0.0042 16.6 0.0 0.013 15.0 0.0 1.7 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 EWM29401.1 - 0.012 15.3 0.0 0.018 14.7 0.0 1.1 1 0 0 1 1 1 0 Asparagine synthase MEKHLA PF08670.11 EWM29403.1 - 1.2e-47 161.4 0.0 1.6e-47 161.0 0.0 1.1 1 0 0 1 1 1 1 MEKHLA domain Sigma70_r4 PF04545.16 EWM29404.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 Myb_DNA-binding PF00249.31 EWM29405.1 - 3e-13 49.7 0.3 6.3e-13 48.7 0.3 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EWM29405.1 - 0.0047 16.8 0.4 0.014 15.3 0.0 1.8 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 EWM29405.1 - 0.048 13.9 0.4 0.048 13.9 0.4 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain PAS_9 PF13426.7 EWM29406.1 - 1.9e-16 60.2 0.0 5.1e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 PAS domain bZIP_2 PF07716.15 EWM29406.1 - 1.8e-06 27.9 13.1 1.8e-06 27.9 13.1 2.1 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 EWM29406.1 - 7.7e-05 22.7 9.8 7.7e-05 22.7 9.8 2.3 3 0 0 3 3 3 1 bZIP transcription factor PAS_4 PF08448.10 EWM29406.1 - 0.0007 19.8 0.0 0.0017 18.6 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 EWM29406.1 - 0.003 17.8 0.0 0.0061 16.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 EWM29406.1 - 0.043 13.8 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 PAS fold Spt5_N PF11942.8 EWM29406.1 - 0.5 11.4 8.9 1.3 10.1 8.9 1.6 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal CDC45 PF02724.14 EWM29406.1 - 0.57 8.4 5.8 0.82 7.9 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 EWM29406.1 - 1 9.0 4.8 2.1 8.0 4.8 1.4 1 0 0 1 1 1 0 FAM176 family PGA2 PF07543.12 EWM29406.1 - 6.8 6.7 10.4 13 5.8 9.7 1.8 1 1 0 1 1 1 0 Protein trafficking PGA2 K_channel_TID PF07941.11 EWM29407.1 - 0.024 15.1 1.6 0.024 15.1 1.6 2.0 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain F-box-like PF12937.7 EWM29407.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 F-box-like TPR_1 PF00515.28 EWM29408.1 - 9.8e-44 145.5 27.5 2.4e-08 33.4 0.3 8.8 8 1 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.17 EWM29408.1 - 2.2e-35 117.9 31.2 2.1e-07 30.5 0.1 9.7 9 1 0 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 EWM29408.1 - 8.3e-32 108.6 20.4 2.5e-07 30.2 0.2 8.2 5 3 3 8 8 8 6 TPR repeat DnaJ PF00226.31 EWM29408.1 - 1.8e-25 88.8 2.9 5.3e-25 87.3 2.9 1.9 1 0 0 1 1 1 1 DnaJ domain TPR_8 PF13181.6 EWM29408.1 - 1.2e-23 81.3 17.8 0.00034 20.6 0.0 9.5 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 EWM29408.1 - 8.6e-20 71.1 31.5 1.3e-05 25.8 0.6 7.5 6 2 1 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 EWM29408.1 - 1.9e-19 69.9 31.2 1.6e-05 25.3 0.0 6.9 6 1 1 7 7 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 EWM29408.1 - 6.6e-19 67.0 29.0 2.2e-05 24.9 0.1 9.4 8 3 3 11 11 9 5 Tetratricopeptide repeat TPR_9 PF13371.6 EWM29408.1 - 9e-16 57.8 20.7 3.2e-07 30.4 0.2 6.4 3 3 2 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 EWM29408.1 - 1.2e-11 44.1 14.1 0.05 14.0 0.0 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 EWM29408.1 - 8.5e-11 42.0 26.7 0.00033 20.9 0.1 7.5 4 3 3 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 EWM29408.1 - 6.5e-09 35.2 13.3 0.57 10.3 0.0 6.9 8 0 0 8 8 6 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EWM29408.1 - 7.3e-09 35.6 15.2 0.00097 19.2 0.1 6.9 8 1 1 9 9 7 2 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 EWM29408.1 - 1.2e-07 31.9 23.8 0.076 13.2 0.3 5.4 4 2 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EWM29408.1 - 2.5e-06 27.7 19.2 0.0056 17.2 0.0 7.5 8 1 1 9 9 7 2 Tetratricopeptide repeat TPR_3 PF07720.12 EWM29408.1 - 1.8e-05 24.6 3.3 0.041 13.9 0.0 4.4 5 0 0 5 5 3 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EWM29408.1 - 0.00052 20.0 3.8 3.6 7.6 0.0 4.9 2 2 2 5 5 5 1 Putative TPR-like repeat Type_III_YscG PF09477.10 EWM29408.1 - 0.0087 16.1 0.0 0.03 14.4 0.0 2.0 1 0 0 1 1 1 1 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_10 PF13374.6 EWM29408.1 - 0.01 15.7 0.2 0.01 15.7 0.2 6.5 8 0 0 8 8 7 0 Tetratricopeptide repeat DUF3856 PF12968.7 EWM29408.1 - 0.051 13.6 6.7 6.3 6.9 0.0 5.7 5 2 0 6 6 6 0 Domain of Unknown Function (DUF3856) DUF5633 PF18656.1 EWM29408.1 - 0.075 12.9 3.1 0.32 10.9 3.1 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF5633) ArsR PF09824.9 EWM29408.1 - 0.08 12.5 0.0 9.1 5.9 0.0 3.0 3 0 0 3 3 3 0 ArsR transcriptional regulator V-SNARE PF05008.15 EWM29408.1 - 0.64 10.4 9.5 0.63 10.5 1.6 3.3 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus TOM20_plant PF06552.12 EWM29408.1 - 0.84 9.4 8.8 1.9 8.2 0.0 3.7 3 1 0 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 DUF2786 PF10979.8 EWM29408.1 - 2.6 8.0 10.9 2.8 7.9 3.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2786) TPR_4 PF07721.14 EWM29408.1 - 2.7 8.9 10.3 2.8 8.8 0.1 4.8 5 0 0 5 5 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 EWM29408.1 - 7 7.1 15.1 1.6 9.2 0.8 4.9 2 1 3 5 5 5 0 Tetratricopeptide repeat CSRNP_N PF16019.5 EWM29409.1 - 0.011 15.6 0.4 0.011 15.6 0.4 4.6 3 2 0 3 3 3 0 Cysteine/serine-rich nuclear protein N-terminus SAP PF02037.27 EWM29409.1 - 0.023 14.4 1.5 0.059 13.1 1.5 1.8 1 0 0 1 1 1 0 SAP domain Telomere_Sde2_2 PF13297.6 EWM29409.1 - 0.27 10.9 4.3 3.2 7.5 0.1 2.6 1 1 1 2 2 2 0 Telomere stability C-terminal Pro_isomerase PF00160.21 EWM29410.1 - 7.4e-21 75.1 0.0 1.3e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pyr_redox_2 PF07992.14 EWM29411.1 - 1.8e-65 221.1 4.6 2.4e-65 220.7 4.6 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EWM29411.1 - 1.1e-31 109.4 0.2 2.9e-31 108.0 0.2 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EWM29411.1 - 2e-20 73.1 6.4 9.2e-19 67.8 0.8 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EWM29411.1 - 2.4e-19 69.7 2.1 8.2e-15 54.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EWM29411.1 - 1.7e-05 24.1 6.8 0.0011 18.1 2.9 2.5 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 EWM29411.1 - 7.2e-05 21.7 3.6 0.023 13.4 1.0 2.7 3 0 0 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.7 EWM29411.1 - 0.00013 21.5 1.7 0.00019 20.9 1.7 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 EWM29411.1 - 0.00076 19.9 1.1 1.4 9.4 0.1 2.6 2 0 0 2 2 2 2 Putative NAD(P)-binding K_oxygenase PF13434.6 EWM29411.1 - 0.00092 18.5 0.0 0.0026 16.9 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EWM29411.1 - 0.00098 18.4 0.2 0.00098 18.4 0.2 1.7 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 EWM29411.1 - 0.0024 17.0 1.7 0.0024 17.0 1.7 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EWM29411.1 - 0.0037 16.6 1.6 0.65 9.3 0.2 2.6 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 EWM29411.1 - 0.0038 16.5 4.7 0.04 13.2 0.2 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EWM29411.1 - 0.0047 17.1 0.9 0.0047 17.1 0.9 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AA_kinase PF00696.28 EWM29411.1 - 0.022 14.3 0.4 2.5 7.7 0.0 2.3 2 1 0 2 2 2 0 Amino acid kinase family NAD_binding_9 PF13454.6 EWM29411.1 - 0.026 14.5 0.3 3.6 7.5 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 EWM29411.1 - 0.062 12.6 3.2 4 6.8 0.0 2.8 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 EWM29411.1 - 0.081 13.4 0.2 12 6.4 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain 3HCDH_N PF02737.18 EWM29411.1 - 0.54 10.1 5.4 5.2 6.9 0.2 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FA_desaturase PF00487.24 EWM29412.1 - 5.4e-28 98.5 22.8 5.4e-28 98.5 22.8 1.8 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 EWM29412.1 - 1.7e-13 50.5 0.0 4e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Imm12 PF15560.6 EWM29412.1 - 0.22 11.5 0.0 0.39 10.7 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 12 ANAPC10 PF03256.16 EWM29413.1 - 2.4e-70 236.0 0.0 3e-70 235.7 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 EWM29413.1 - 0.00039 20.5 0.2 0.00075 19.6 0.1 1.5 2 0 0 2 2 2 1 F5/8 type C domain PITH PF06201.13 EWM29413.1 - 0.082 13.1 0.0 0.41 10.9 0.0 1.8 2 0 0 2 2 2 0 PITH domain Ank_2 PF12796.7 EWM29414.1 - 2.3e-25 89.0 0.4 3.2e-08 34.0 0.0 3.7 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EWM29414.1 - 7.9e-22 77.3 5.3 1.8e-09 37.9 0.2 5.5 2 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EWM29414.1 - 1.5e-20 73.0 1.3 1e-05 25.7 0.3 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EWM29414.1 - 6.7e-15 54.8 6.9 0.0032 17.8 1.3 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 EWM29414.1 - 1.2e-11 43.7 2.0 0.21 12.3 0.0 6.1 6 0 0 6 6 6 3 Ankyrin repeat Peptidase_M22 PF00814.25 EWM29415.1 - 3.6e-69 233.5 0.6 1.4e-62 211.9 0.8 3.0 2 1 0 2 2 2 2 Glycoprotease family Carbam_trans_N PF02543.15 EWM29415.1 - 0.035 13.8 0.2 0.078 12.6 0.0 1.6 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus LSM14 PF12701.7 EWM29417.1 - 2.1e-28 98.2 0.1 2.9e-28 97.8 0.1 1.2 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 EWM29417.1 - 2.7e-07 30.6 0.0 4.6e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain FDF PF09532.10 EWM29417.1 - 0.0003 21.6 0.6 0.00066 20.5 0.0 1.7 2 0 0 2 2 2 1 FDF domain MSA-2c PF12238.8 EWM29417.1 - 4.1 7.4 6.2 5.6 6.9 6.2 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF4106 PF13388.6 EWM29417.1 - 7.8 5.6 12.9 11 5.2 12.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Thioesterase PF00975.20 EWM29418.1 - 3.7e-05 23.9 0.1 9.7e-05 22.6 0.1 1.7 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 EWM29418.1 - 0.00064 20.4 4.4 0.0015 19.2 4.4 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EWM29418.1 - 0.073 12.3 0.1 0.21 10.8 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 START PF01852.19 EWM29419.1 - 8.3e-17 61.3 0.1 4.9e-11 42.4 0.0 2.4 2 0 0 2 2 2 2 START domain ACBP PF00887.19 EWM29419.1 - 5.2e-14 52.2 0.0 1e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein PH PF00169.29 EWM29419.1 - 1.7e-12 47.8 0.0 3e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 PH domain 2-oxoacid_dh PF00198.23 EWM29419.1 - 3e-05 23.6 0.1 0.0002 20.9 0.0 2.0 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) PH_11 PF15413.6 EWM29419.1 - 0.0024 18.3 0.1 0.03 14.7 0.1 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 EWM29419.1 - 0.0055 16.9 0.1 0.45 10.8 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain DUF4532 PF15046.6 EWM29419.1 - 0.032 13.4 1.3 5.3 6.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4532) Pkinase PF00069.25 EWM29420.1 - 7.6e-22 77.9 0.0 9.9e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM29420.1 - 0.00021 20.7 0.0 0.00028 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EWM29420.1 - 0.0021 17.4 0.0 0.0026 17.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like SARAF PF06682.12 EWM29421.1 - 0.02 14.6 8.6 0.023 14.4 8.6 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF3292 PF11696.8 EWM29421.1 - 1.4 7.2 4.2 2.2 6.6 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) VATC PF18716.1 EWM29422.1 - 9e-12 44.7 0.9 1.7e-11 43.8 0.9 1.5 1 0 0 1 1 1 1 Vms1-associating treble clef domain PTE PF02126.18 EWM29422.1 - 4.6e-09 36.1 0.0 9.4e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Phosphotriesterase family HAD_SAK_2 PF18143.1 EWM29422.1 - 0.084 13.2 0.0 0.48 10.7 0.0 2.1 2 0 0 2 2 2 0 HAD domain in Swiss Army Knife RNA repair proteins NAD_Gly3P_dh_C PF07479.14 EWM29423.1 - 6.7e-48 162.6 0.0 1.1e-47 161.8 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 EWM29423.1 - 7.6e-46 155.9 0.0 1.1e-45 155.4 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 EWM29423.1 - 0.00023 21.7 0.0 0.004 17.7 0.0 2.4 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 EWM29423.1 - 0.012 16.0 0.0 0.026 15.0 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Pkinase PF00069.25 EWM29424.1 - 5.9e-31 107.8 0.0 8.3e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM29424.1 - 2.2e-17 63.2 0.1 3.1e-17 62.7 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EWM29424.1 - 0.0044 17.0 0.1 0.011 15.6 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EWM29424.1 - 0.012 15.3 0.2 0.023 14.3 0.2 1.4 1 0 0 1 1 1 0 RIO1 family Acyl-CoA_dh_1 PF00441.24 EWM29425.1 - 5.9e-37 127.2 2.3 9e-37 126.6 2.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EWM29425.1 - 3e-30 105.2 0.2 6.8e-30 104.0 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EWM29425.1 - 1.9e-23 82.4 0.1 3.6e-23 81.6 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EWM29425.1 - 6e-16 58.9 0.1 1.2e-15 58.0 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Lyase_aromatic PF00221.19 EWM29427.1 - 8e-23 80.8 3.0 1.6e-17 63.3 0.1 2.5 2 1 0 3 3 3 2 Aromatic amino acid lyase Fer2_3 PF13085.6 EWM29428.1 - 6.7e-32 109.7 0.0 1.3e-31 108.8 0.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 EWM29428.1 - 2e-09 37.8 5.7 2e-09 37.8 5.7 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 EWM29428.1 - 1.7e-08 34.5 3.3 1.7e-08 34.5 3.3 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EWM29428.1 - 2.6e-08 34.2 13.1 4.6e-08 33.4 8.2 2.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer2 PF00111.27 EWM29428.1 - 0.0014 18.6 2.6 0.0072 16.3 0.2 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 EWM29428.1 - 0.0045 17.5 13.2 0.0097 16.5 9.7 2.9 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 EWM29428.1 - 0.025 14.8 7.1 0.052 13.8 0.2 2.6 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 EWM29428.1 - 0.04 14.9 9.9 0.92 10.5 2.2 3.0 3 0 0 3 3 3 0 4Fe-4S double cluster binding domain Fer4_9 PF13187.6 EWM29428.1 - 0.11 12.7 15.1 0.033 14.3 9.6 2.6 2 1 1 3 3 3 0 4Fe-4S dicluster domain PGI PF00342.19 EWM29429.1 - 1.6e-181 604.2 0.0 2.2e-181 603.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoglucose isomerase NAD_binding_5 PF07994.12 EWM29429.1 - 2.4e-57 194.8 0.0 3.7e-57 194.1 0.0 1.3 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 EWM29429.1 - 8.7e-27 93.5 0.0 1.6e-26 92.7 0.0 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase PfkB PF00294.24 EWM29429.1 - 7.4e-17 61.6 2.4 1.6e-09 37.5 0.3 2.9 2 1 0 2 2 2 2 pfkB family carbohydrate kinase MinE PF03776.14 EWM29430.1 - 2.4e-14 53.1 0.5 3.6e-14 52.5 0.5 1.3 1 0 0 1 1 1 1 Septum formation topological specificity factor MinE ubiquitin PF00240.23 EWM29431.1 - 6.2e-35 118.8 0.5 1.6e-34 117.5 0.6 1.6 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.19 EWM29431.1 - 8.7e-20 70.6 3.7 8.7e-20 70.6 3.7 1.8 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 EWM29431.1 - 1.9e-16 59.7 0.7 1.9e-16 59.7 0.7 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EWM29431.1 - 2.3e-07 31.2 0.2 1.6e-05 25.2 0.1 2.7 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EWM29431.1 - 0.00029 20.9 0.5 0.00063 19.8 0.5 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Zn_ribbon_SprT PF17283.2 EWM29431.1 - 0.0011 18.8 2.0 0.0018 18.1 2.0 1.4 1 0 0 1 1 1 1 SprT-like zinc ribbon domain TBK1_ULD PF18396.1 EWM29431.1 - 0.0024 17.8 0.0 0.0034 17.3 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EWM29431.1 - 0.0032 17.8 0.8 0.011 16.0 0.1 2.0 1 1 0 2 2 2 1 Ubiquitin-like domain DUF2407 PF10302.9 EWM29431.1 - 0.004 17.7 0.6 0.0058 17.2 0.6 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EWM29431.1 - 0.026 14.6 0.8 9.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain Plexin_cytopl PF08337.12 EWM29431.1 - 0.033 12.9 2.4 0.68 8.5 2.4 2.5 1 1 0 1 1 1 0 Plexin cytoplasmic RasGAP domain Nudix_N_2 PF14803.6 EWM29431.1 - 0.12 12.3 2.6 0.5 10.3 2.3 2.2 2 0 0 2 2 2 0 Nudix N-terminal tRNA-synt_His PF13393.6 EWM29435.1 - 0.0029 16.9 0.0 0.0034 16.7 0.0 1.0 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EWM29436.1 - 7.9e-11 42.0 0.0 1.1e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 EWM29436.1 - 0.0014 18.2 0.0 0.0017 17.9 0.0 1.1 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs Amidohydro_2 PF04909.14 EWM29438.1 - 1.7e-05 24.7 0.0 2e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase AAA_16 PF13191.6 EWM29439.1 - 7.3e-10 39.5 0.5 2e-09 38.0 0.1 1.9 2 0 0 2 2 2 1 AAA ATPase domain ORC4_C PF14629.6 EWM29439.1 - 2.4e-08 33.6 0.2 4.4e-08 32.8 0.2 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_22 PF13401.6 EWM29439.1 - 5e-08 33.3 0.0 1.1e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EWM29439.1 - 8.9e-07 29.4 0.0 3.6e-06 27.4 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DAP3 PF10236.9 EWM29439.1 - 0.0033 16.7 0.0 0.036 13.2 0.0 2.2 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 TniB PF05621.11 EWM29439.1 - 0.0047 16.4 0.0 0.036 13.5 0.0 2.1 2 0 0 2 2 2 1 Bacterial TniB protein AAA_7 PF12775.7 EWM29439.1 - 0.0074 15.8 0.0 0.021 14.3 0.0 1.6 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF815 PF05673.13 EWM29439.1 - 0.01 15.0 0.0 0.026 13.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 EWM29439.1 - 0.046 13.7 0.0 0.55 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 EWM29439.1 - 0.15 12.4 0.0 0.51 10.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 EWM29439.1 - 0.18 11.8 0.0 6.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit 2-Hacid_dh_C PF02826.19 EWM29440.1 - 3.5e-51 173.1 0.0 5.8e-51 172.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EWM29440.1 - 4.3e-26 91.1 0.0 5.6e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EWM29440.1 - 2.3e-07 31.1 0.2 4.1e-06 27.1 0.0 2.4 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 EWM29440.1 - 1.6e-05 25.0 0.3 3.4e-05 24.0 0.3 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.21 EWM29440.1 - 0.031 13.6 0.2 0.058 12.7 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.12 EWM29440.1 - 0.1 12.2 0.0 0.47 10.0 0.0 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain XdhC_C PF13478.6 EWM29440.1 - 0.1 13.1 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain F420_oxidored PF03807.17 EWM29440.1 - 0.15 12.7 0.5 2 9.1 0.1 2.7 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 EWM29440.1 - 0.36 11.3 2.0 8.1 6.9 0.1 2.5 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_transf_22 PF03901.17 EWM29441.1 - 1.5e-74 251.8 0.3 2.2e-74 251.1 0.3 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family ELO PF01151.18 EWM29442.1 - 2.3e-67 227.2 15.0 3.3e-67 226.7 15.0 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF5556 PF17711.1 EWM29443.1 - 0.029 14.3 0.1 0.046 13.7 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5556) Methyltr_RsmB-F PF01189.17 EWM29444.1 - 7.1e-24 84.6 0.0 2.2e-14 53.6 0.0 2.5 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 EWM29444.1 - 2.2e-05 24.3 0.0 0.0094 15.8 0.0 2.6 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_25 PF13649.6 EWM29444.1 - 2.3e-05 25.0 0.9 0.00065 20.4 0.1 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM29444.1 - 0.00038 21.0 0.5 0.15 12.8 0.1 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 EWM29444.1 - 0.0005 19.9 0.1 0.27 11.1 0.1 2.3 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 EWM29444.1 - 0.0028 17.0 0.0 0.044 13.1 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 EWM29444.1 - 0.0035 17.5 0.1 0.032 14.4 0.1 2.1 2 0 0 2 2 2 1 FtsJ-like methyltransferase MTS PF05175.14 EWM29444.1 - 0.028 14.0 0.0 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain AMP-binding PF00501.28 EWM29446.1 - 2e-79 267.2 0.0 2.6e-79 266.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PEP_mutase PF13714.6 EWM29447.1 - 8e-52 176.1 0.0 1.1e-51 175.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 EWM29447.1 - 1.1e-12 47.2 0.1 1.7e-12 46.6 0.1 1.3 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.15 EWM29447.1 - 0.0074 15.7 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase WD40 PF00400.32 EWM29450.1 - 5.3e-36 122.0 4.6 2.3e-08 34.6 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM29450.1 - 4.8e-11 42.8 0.0 0.13 12.5 0.0 4.4 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EWM29450.1 - 0.0025 16.5 0.2 0.1 11.2 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.14 EWM29450.1 - 0.28 10.2 0.0 0.48 9.4 0.0 1.3 1 0 0 1 1 1 0 Coatomer WD associated region Rad60-SLD PF11976.8 EWM29451.1 - 5e-17 61.5 1.0 7.7e-17 60.9 1.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EWM29451.1 - 9.4e-11 41.3 0.9 1.4e-10 40.7 0.9 1.3 1 0 0 1 1 1 1 Ubiquitin family SRP9-21 PF05486.12 EWM29451.1 - 0.0079 16.6 2.5 0.011 16.1 2.5 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) RPE65 PF03055.15 EWM29452.1 - 6.2e-91 305.9 0.0 8.2e-91 305.5 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein RPE65 PF03055.15 EWM29453.1 - 5.6e-49 167.6 0.0 6.7e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein SAP PF02037.27 EWM29456.1 - 1e-10 41.1 1.2 9.3e-05 22.1 0.4 3.4 3 0 0 3 3 3 2 SAP domain DnaJ PF00226.31 EWM29456.1 - 3.6e-09 36.6 0.0 8.8e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain zf-C2HC_2 PF13913.6 EWM29456.1 - 0.022 14.7 2.2 0.022 14.7 2.2 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DZR PF12773.7 EWM29456.1 - 2.1 8.4 9.8 43 4.2 0.1 3.3 2 1 0 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 EWM29456.1 - 6.2 6.9 9.0 1.3 9.0 1.4 2.8 2 1 0 2 2 2 0 zinc-ribbons zf-TFIIB PF13453.6 EWM29456.1 - 6.6 6.2 9.0 36 3.8 0.4 3.6 3 0 0 3 3 3 0 Transcription factor zinc-finger DUF1731 PF08338.11 EWM29457.1 - 3.9e-15 55.4 0.2 1e-14 54.1 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) Epimerase PF01370.21 EWM29457.1 - 3.1e-07 30.1 0.2 1.3e-06 28.1 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EWM29457.1 - 0.13 11.4 0.7 9.5 5.3 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EWM29457.1 - 0.22 10.6 0.1 0.39 9.8 0.1 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Ldh_1_N PF00056.23 EWM29457.1 - 0.3 11.2 1.4 0.94 9.6 1.4 1.9 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain zf-MYND PF01753.18 EWM29459.1 - 1.2e-14 54.0 41.7 6.2e-09 35.8 17.8 3.6 5 0 0 5 5 5 2 MYND finger tRNA-synt_1b PF00579.25 EWM29460.1 - 8.4e-90 301.0 0.0 1.1e-89 300.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) UQ_con PF00179.26 EWM29462.1 - 2.2e-11 43.6 0.1 8.4e-11 41.7 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme PRIMA1 PF16101.5 EWM29462.1 - 2.6 8.1 4.9 5.1 7.2 4.9 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 dCMP_cyt_deam_1 PF00383.23 EWM29463.1 - 2e-05 24.4 0.0 3.8e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Orthopox_A5L PF06193.11 EWM29463.1 - 0.0096 15.4 2.4 0.013 15.0 2.4 1.1 1 0 0 1 1 1 1 Orthopoxvirus A5L protein-like TPPII_N PF12583.8 EWM29463.1 - 0.62 10.7 4.0 0.67 10.5 3.3 1.5 1 1 0 1 1 1 0 Tripeptidyl peptidase II N terminal dCMP_cyt_deam_1 PF00383.23 EWM29464.1 - 1.7e-25 88.8 0.0 2.6e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EWM29464.1 - 1.3e-11 44.4 0.0 1.9e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase Orthopox_A5L PF06193.11 EWM29464.1 - 0.014 14.9 2.2 0.019 14.4 2.2 1.2 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like PBP PF01161.20 EWM29466.1 - 2.3e-07 31.2 0.0 0.00012 22.3 0.0 2.4 2 1 0 2 2 2 2 Phosphatidylethanolamine-binding protein T4BSS_DotI_IcmL PF11393.8 EWM29466.1 - 0.16 11.5 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Type-IV b secretion system, inner-membrane complex component SLS PF14611.6 EWM29466.1 - 0.18 11.6 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator DUF5555 PF17710.1 EWM29467.1 - 0.12 11.9 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5555) MMPL PF03176.15 EWM29469.1 - 2.2e-43 148.5 16.9 4.2e-43 147.6 16.9 1.3 1 1 0 1 1 1 1 MMPL family MRAP PF15183.6 EWM29469.1 - 0.086 12.8 0.1 0.22 11.5 0.1 1.7 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family Sterol-sensing PF12349.8 EWM29469.1 - 6.1 6.7 12.2 11 5.9 6.0 2.8 2 1 0 2 2 2 0 Sterol-sensing domain of SREBP cleavage-activation WD40 PF00400.32 EWM29470.1 - 5.1e-12 46.1 1.7 0.0056 17.5 0.0 6.1 5 1 0 5 5 5 3 WD domain, G-beta repeat YabA PF06156.13 EWM29470.1 - 6e-05 23.6 0.3 0.00014 22.4 0.3 1.6 1 0 0 1 1 1 1 Initiation control protein YabA ANAPC4_WD40 PF12894.7 EWM29470.1 - 0.00026 21.2 0.0 0.52 10.6 0.0 3.7 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 EWM29470.1 - 0.18 11.0 0.0 0.33 10.1 0.0 1.4 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller NRBF2 PF08961.10 EWM29470.1 - 0.19 11.3 1.4 0.31 10.6 1.4 1.2 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator TSC22 PF01166.18 EWM29470.1 - 0.23 11.8 2.0 0.52 10.7 1.7 1.8 1 1 0 1 1 1 0 TSC-22/dip/bun family bZIP_1 PF00170.21 EWM29470.1 - 0.63 10.2 2.4 3.8 7.7 1.9 2.1 1 1 1 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.15 EWM29470.1 - 1.8 8.7 3.3 14 5.9 1.2 2.2 2 0 0 2 2 2 0 Basic region leucine zipper NAD_binding_1 PF00175.21 EWM29473.1 - 1.3e-33 115.9 0.0 3.3e-33 114.6 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EWM29473.1 - 2.7e-33 114.3 0.0 4.4e-33 113.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EWM29473.1 - 9.3e-06 25.8 0.0 0.00015 21.9 0.0 2.2 1 1 0 2 2 2 1 Ferric reductase NAD binding domain DUF4131 PF13567.6 EWM29473.1 - 0.072 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF5598 PF18127.1 EWM29474.1 - 0.051 14.0 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5598) PCI PF01399.27 EWM29476.1 - 3.8e-13 49.9 0.2 7.8e-13 48.9 0.2 1.5 1 0 0 1 1 1 1 PCI domain DUF2379 PF09543.10 EWM29476.1 - 0.047 13.9 0.1 0.13 12.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) DUF2379 PF09543.10 EWM29477.1 - 0.043 14.0 0.1 0.1 12.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) TPR_11 PF13414.6 EWM29477.1 - 0.28 10.9 1.7 13 5.6 0.1 3.2 3 0 0 3 3 3 0 TPR repeat Retrotran_gag_2 PF14223.6 EWM29479.1 - 1.9e-09 37.3 0.1 2.8e-09 36.7 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF1759 PF03564.15 EWM29479.1 - 0.014 15.3 0.1 0.02 14.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) Myb_DNA-binding PF00249.31 EWM29480.1 - 2.4e-31 107.7 5.0 7.4e-12 45.3 0.1 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EWM29480.1 - 7.8e-27 93.3 0.5 2.9e-13 49.8 0.0 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EWM29480.1 - 0.019 14.8 0.0 0.077 12.9 0.0 2.0 2 0 0 2 2 2 0 Myb DNA-binding like Helicase_C PF00271.31 EWM29482.1 - 4.9e-15 55.8 0.0 8.9e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain VWA_2 PF13519.6 EWM29484.1 - 0.0021 18.7 0.0 0.026 15.2 0.0 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain CYTL1 PF15153.6 EWM29484.1 - 0.077 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Cytokine-like protein 1 DUF3079 PF11278.8 EWM29484.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3079) Helicase_C PF00271.31 EWM29485.1 - 5.1e-19 68.6 0.0 7.8e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TLD PF07534.16 EWM29486.1 - 0.003 17.8 0.0 0.0069 16.6 0.0 1.5 2 0 0 2 2 2 1 TLD TLD PF07534.16 EWM29487.1 - 0.0027 17.9 0.0 0.006 16.8 0.0 1.5 2 0 0 2 2 2 1 TLD Bromodomain PF00439.25 EWM29490.1 - 1.2e-17 63.7 0.0 2.5e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Bromodomain zf-TAZ PF02135.16 EWM29490.1 - 7.5e-15 55.1 13.3 7.5e-15 55.1 13.3 2.2 2 0 0 2 2 2 1 TAZ zinc finger PHD PF00628.29 EWM29490.1 - 7.7e-08 32.1 3.8 2.5e-07 30.5 3.8 1.9 1 0 0 1 1 1 1 PHD-finger Presenilin PF01080.17 EWM29490.1 - 0.00057 18.8 6.0 0.00057 18.8 6.0 2.3 2 0 0 2 2 2 1 Presenilin DUF2722 PF10846.8 EWM29490.1 - 0.0011 18.0 11.9 0.0011 18.0 11.9 5.4 4 1 1 5 5 5 1 Protein of unknown function (DUF2722) DUF902 PF06001.13 EWM29490.1 - 1.1 9.8 6.5 2.2 8.8 6.5 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF902) Band_3_cyto PF07565.13 EWM29490.1 - 3.7 7.3 34.4 1.5 8.5 0.7 3.6 3 0 0 3 3 3 0 Band 3 cytoplasmic domain zf-TAZ PF02135.16 EWM29492.1 - 1.8e-06 28.3 7.3 3.1e-06 27.5 7.3 1.4 1 0 0 1 1 1 1 TAZ zinc finger PPR PF01535.20 EWM29493.1 - 0.00095 19.3 0.1 0.47 10.8 0.0 2.4 2 0 0 2 2 2 2 PPR repeat PPR_1 PF12854.7 EWM29493.1 - 0.0029 17.3 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 1 PPR repeat PPR_2 PF13041.6 EWM29493.1 - 0.075 13.2 0.0 8.4 6.7 0.0 2.3 2 0 0 2 2 2 0 PPR repeat family Ctr PF04145.15 EWM29496.1 - 2.1e-15 57.7 12.9 1.7e-14 54.7 12.9 2.0 1 1 0 1 1 1 1 Ctr copper transporter family Babuvirus_MP PF07234.11 EWM29496.1 - 0.022 14.9 0.0 0.096 12.9 0.0 1.9 2 0 0 2 2 2 0 Movement and RNA silencing protein RseC_MucC PF04246.12 EWM29496.1 - 8.7 6.3 5.7 3.8 7.5 1.6 2.0 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Ctr PF04145.15 EWM29497.1 - 8.5e-16 58.9 12.8 8e-15 55.7 12.8 2.0 1 1 0 1 1 1 1 Ctr copper transporter family Babuvirus_MP PF07234.11 EWM29497.1 - 0.011 15.9 0.0 0.056 13.6 0.0 1.9 2 0 0 2 2 2 0 Movement and RNA silencing protein DUF4704 PF15787.5 EWM29500.1 - 0.03 13.6 0.0 0.057 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4704) PPR_2 PF13041.6 EWM29502.1 - 3.8e-18 65.4 0.0 0.00024 21.2 0.0 5.6 3 1 2 5 5 5 4 PPR repeat family PPR_3 PF13812.6 EWM29502.1 - 6.2e-18 64.6 0.0 3.6e-06 27.0 0.0 4.5 4 0 0 4 4 4 3 Pentatricopeptide repeat domain PPR PF01535.20 EWM29502.1 - 3e-17 61.6 0.0 6.8e-05 22.8 0.0 5.1 4 0 0 4 4 4 4 PPR repeat PPR_1 PF12854.7 EWM29502.1 - 7.5e-10 38.3 0.0 0.0023 17.6 0.0 4.9 5 0 0 5 5 5 2 PPR repeat PPR_long PF17177.4 EWM29502.1 - 1e-05 25.1 0.0 0.00073 19.0 0.0 2.6 1 1 2 3 3 3 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 EWM29502.1 - 0.00013 22.5 6.7 0.016 16.0 0.2 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EWM29502.1 - 0.018 15.5 3.4 4.3 7.9 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 EWM29502.1 - 0.03 14.8 0.0 0.073 13.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial transcriptional activator domain TPR_MalT PF17874.1 EWM29502.1 - 0.078 12.3 0.9 3.5 6.9 0.0 2.5 2 1 0 2 2 2 0 MalT-like TPR region TPR_12 PF13424.6 EWM29502.1 - 0.09 13.1 2.4 22 5.4 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EWM29502.1 - 0.11 12.6 0.2 0.56 10.4 0.0 2.3 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 EWM29502.1 - 0.22 12.2 7.2 8.5 7.3 0.7 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat ACC_epsilon PF13822.6 EWM29502.1 - 0.36 11.5 7.0 3.9 8.2 0.0 3.6 3 0 0 3 3 3 0 Acyl-CoA carboxylase epsilon subunit JAB PF01398.21 EWM29503.1 - 3.5e-27 94.7 0.0 4.6e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease FAM176 PF14851.6 EWM29504.1 - 0.01 15.5 1.1 0.022 14.4 0.1 1.8 1 1 1 2 2 2 0 FAM176 family VDE PF07137.11 EWM29505.1 - 1.6e-21 76.9 4.6 2.1e-21 76.5 4.6 1.1 1 0 0 1 1 1 1 VDE lipocalin domain DUF4241 PF14025.6 EWM29505.1 - 0.03 14.6 0.0 0.047 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) NARP1 PF12569.8 EWM29506.1 - 0.18 10.7 3.1 0.24 10.3 3.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF755 PF05501.11 EWM29506.1 - 0.61 10.4 13.1 1 9.7 13.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Presenilin PF01080.17 EWM29506.1 - 0.98 8.1 1.9 1.2 7.8 1.9 1.1 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 EWM29506.1 - 1.5 7.5 4.1 1.9 7.2 4.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SWIRM-assoc_2 PF16496.5 EWM29506.1 - 1.6 7.5 6.6 2.3 7.0 6.6 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal CS PF04969.16 EWM29507.1 - 4.3e-10 40.5 0.1 4.3e-10 40.5 0.1 1.4 2 0 0 2 2 2 1 CS domain DUF1087 PF06465.13 EWM29507.1 - 0.037 14.0 0.1 0.11 12.6 0.1 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) DUF1654 PF07867.11 EWM29507.1 - 0.13 12.0 0.3 0.29 10.9 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) Forkhead_N PF08430.12 EWM29507.1 - 0.45 11.1 10.6 0.62 10.7 10.6 1.1 1 0 0 1 1 1 0 Forkhead N-terminal region RNA_pol_A_bac PF01000.26 EWM29508.1 - 5.8e-08 33.1 0.0 3e-07 30.8 0.0 2.1 2 1 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EWM29508.1 - 5.9e-08 32.0 0.0 6.3e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_7 PF12838.7 EWM29508.1 - 0.023 15.3 2.8 0.048 14.2 2.8 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain LAMTOR5 PF16672.5 EWM29508.1 - 0.11 12.5 0.0 2 8.4 0.0 2.2 2 0 0 2 2 2 0 Ragulator complex protein LAMTOR5 RNA_pol_A_bac PF01000.26 EWM29509.1 - 3.9e-11 43.3 0.0 6.3e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EWM29509.1 - 2e-10 40.0 0.0 2.1e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Attacin_N PF03768.15 EWM29510.1 - 0.042 14.0 0.0 0.061 13.5 0.0 1.2 1 0 0 1 1 1 0 Attacin, N-terminal region RabGAP-TBC PF00566.18 EWM29511.1 - 1.8e-38 132.4 0.0 2.8e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CHAD PF05235.14 EWM29511.1 - 0.0073 16.3 2.4 0.017 15.1 2.4 1.6 1 0 0 1 1 1 1 CHAD domain HD_3 PF13023.6 EWM29513.1 - 9e-43 146.0 0.1 1.2e-42 145.7 0.1 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 EWM29513.1 - 8e-12 45.3 0.0 1.1e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 EWM29513.1 - 0.00012 22.3 0.3 0.00018 21.7 0.3 1.2 1 0 0 1 1 1 1 HD domain HPP PF04982.13 EWM29513.1 - 0.056 13.6 0.1 0.08 13.1 0.1 1.4 1 0 0 1 1 1 0 HPP family EST1_DNA_bind PF10373.9 EWM29514.1 - 2.9e-13 49.9 0.0 4.5e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain DUF2017 PF09438.10 EWM29514.1 - 0.024 14.5 1.5 0.062 13.2 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2017) Fer2 PF00111.27 EWM29515.1 - 9.9e-11 41.4 1.3 1.6e-10 40.8 1.3 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain PG_binding_3 PF09374.10 EWM29515.1 - 0.13 12.5 0.0 0.32 11.3 0.0 1.7 2 0 0 2 2 2 0 Predicted Peptidoglycan domain ECH_1 PF00378.20 EWM29516.1 - 4.8e-48 163.7 0.0 5.6e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EWM29516.1 - 4.2e-27 95.5 0.0 7.3e-27 94.7 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Sec63 PF02889.16 EWM29517.1 - 7.9e-20 71.1 0.0 1.1e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.31 EWM29517.1 - 1e-19 70.4 0.1 2e-19 69.4 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain 7tm_1 PF00001.21 EWM29517.1 - 6.2 6.1 5.9 50 3.1 0.9 2.8 2 1 1 3 3 3 0 7 transmembrane receptor (rhodopsin family) Proteasome PF00227.26 EWM29521.1 - 1.1e-26 93.4 0.0 1.8e-22 79.8 0.0 2.0 2 0 0 2 2 2 2 Proteasome subunit Proteasome PF00227.26 EWM29522.1 - 1.3e-09 37.9 0.1 2.3e-05 24.0 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit FAD_binding_3 PF01494.19 EWM29523.1 - 8.7e-20 71.3 0.2 1.1e-09 38.0 0.2 2.5 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 EWM29523.1 - 0.0002 21.1 0.0 0.00041 20.1 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EWM29523.1 - 0.012 15.8 0.0 0.03 14.6 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.10 EWM29523.1 - 0.017 14.1 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Pyr_redox_2 PF07992.14 EWM29523.1 - 0.073 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EWM29523.1 - 1.1 8.2 3.3 0.85 8.6 0.3 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Methyltransf_11 PF08241.12 EWM29524.1 - 3.3e-15 56.5 0.0 7.3e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM29524.1 - 3e-14 53.5 0.0 7.3e-14 52.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM29524.1 - 7.5e-08 32.3 0.0 9.9e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EWM29524.1 - 7.5e-08 32.0 0.0 2.1e-07 30.5 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EWM29524.1 - 1.6e-07 31.3 0.0 2.1e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EWM29524.1 - 1.2e-06 29.1 0.0 3.1e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.15 EWM29524.1 - 0.0043 16.9 0.0 0.006 16.4 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase MetW PF07021.12 EWM29524.1 - 0.12 11.9 0.0 0.26 10.9 0.0 1.5 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Pyr_redox_2 PF07992.14 EWM29526.1 - 2.4e-32 112.4 0.2 3.9e-32 111.7 0.1 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EWM29526.1 - 4e-19 68.9 0.0 1.4e-18 67.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EWM29526.1 - 9.5e-11 42.1 0.4 8.3e-07 29.5 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EWM29526.1 - 7.9e-08 31.9 0.0 9.6e-05 21.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 EWM29526.1 - 0.00019 20.9 0.0 0.036 13.4 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 EWM29526.1 - 0.00039 19.6 0.8 0.0017 17.5 0.4 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EWM29526.1 - 0.00099 18.6 0.8 0.0014 18.1 0.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EWM29526.1 - 0.001 18.4 0.0 0.13 11.5 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 EWM29526.1 - 0.0011 17.7 0.2 0.0017 17.1 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 EWM29526.1 - 0.0017 17.6 0.9 0.0027 16.8 0.9 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EWM29526.1 - 0.021 15.1 0.3 0.021 15.1 0.3 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EWM29526.1 - 0.021 14.4 0.1 0.035 13.7 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase XdhC_C PF13478.6 EWM29526.1 - 0.079 13.5 0.0 9.4 6.8 0.0 2.5 2 0 0 2 2 2 0 XdhC Rossmann domain Phage_TTP_12 PF16461.5 EWM29526.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Lambda phage tail tube protein, TTP Lycopene_cycl PF05834.12 EWM29526.1 - 0.14 11.2 0.2 0.26 10.3 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein SNF2_N PF00176.23 EWM29527.1 - 5.7e-49 166.7 0.0 7.6e-49 166.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EWM29527.1 - 2.9e-10 40.5 0.0 6.8e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EWM29527.1 - 8.5e-10 38.9 0.0 1.5e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EWM29527.1 - 6.7e-06 26.0 0.0 1.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EWM29527.1 - 0.0011 18.7 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 EWM29527.1 - 0.0068 16.7 0.0 0.019 15.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain RhlB PF12300.8 EWM29527.1 - 0.012 15.7 1.1 0.012 15.7 1.1 2.4 2 1 0 2 2 2 0 ATP-dependent RNA helicase RhlB DUF1206 PF06724.11 EWM29528.1 - 1.4 9.1 5.0 16 5.7 0.0 3.5 4 0 0 4 4 4 0 Domain of Unknown Function (DUF1206) BmKX PF09132.10 EWM29529.1 - 0.48 10.4 7.3 1.3 9.0 0.3 3.4 3 0 0 3 3 3 0 BmKX DUF454 PF04304.13 EWM29530.1 - 0.011 15.7 2.5 0.13 12.3 1.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF454) VAR1 PF05316.12 EWM29530.1 - 0.093 11.8 0.1 0.1 11.6 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein (VAR1) Lactamase_B_2 PF12706.7 EWM29531.1 - 2e-15 56.9 0.2 3.2e-14 52.9 0.2 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EWM29531.1 - 0.33 10.9 4.9 1.6 8.7 5.0 2.3 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily DUF4082 PF13313.6 EWM29532.1 - 1.8e-19 70.2 0.2 5.9e-19 68.5 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4082) DUF4602 PF15375.6 EWM29533.1 - 7.4e-15 55.5 4.8 1.3e-14 54.6 4.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4602) UNC-50 PF05216.13 EWM29534.1 - 2.6e-65 220.1 10.8 3.2e-65 219.8 10.8 1.0 1 0 0 1 1 1 1 UNC-50 family Condensation PF00668.20 EWM29535.1 - 2.3e-06 26.5 0.0 1.6e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Condensation domain DAGAT PF03982.13 EWM29536.1 - 7.2e-33 113.8 0.0 1.2e-32 113.1 0.0 1.3 1 1 0 1 1 1 1 Diacylglycerol acyltransferase Not3 PF04065.15 EWM29537.1 - 8.1e-79 264.3 28.6 8.1e-79 264.3 28.6 3.1 3 0 0 3 3 3 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 EWM29537.1 - 3.1e-43 147.0 7.2 3.1e-43 147.0 7.2 4.1 3 1 0 3 3 3 1 NOT2 / NOT3 / NOT5 family DUF2849 PF11011.8 EWM29537.1 - 7.2 7.3 0.0 7.2 7.3 0.0 4.1 4 1 1 5 5 5 0 Protein of unknown function (DUF2849) Presenilin PF01080.17 EWM29539.1 - 7.7 5.2 8.6 12 4.6 8.6 1.2 1 0 0 1 1 1 0 Presenilin DNA_photolyase PF00875.18 EWM29541.1 - 4e-27 95.2 0.0 7.1e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase DUF1904 PF08921.11 EWM29541.1 - 0.21 11.9 0.0 0.85 9.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1904) Mpv17_PMP22 PF04117.12 EWM29542.1 - 2.4e-13 50.1 2.4 1.6e-12 47.5 0.2 2.8 3 0 0 3 3 3 1 Mpv17 / PMP22 family AA_kinase PF00696.28 EWM29543.1 - 9.1e-36 123.7 0.1 1.7e-35 122.8 0.1 1.5 1 0 0 1 1 1 1 Amino acid kinase family Aldedh PF00171.22 EWM29543.1 - 4.4e-13 48.6 2.1 9.2e-10 37.6 1.8 3.0 3 1 0 3 3 3 2 Aldehyde dehydrogenase family Biotin_lipoyl PF00364.22 EWM29544.1 - 1.2e-13 50.7 0.0 2e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme RhoGEF67_u2 PF16614.5 EWM29544.1 - 0.074 13.1 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Unstructured region two on RhoGEF 6 and 7 Myb_DNA-binding PF00249.31 EWM29546.1 - 0.00011 22.3 0.0 0.00021 21.4 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EWM29546.1 - 0.097 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Myb DNA-binding like SRP-alpha_N PF04086.13 EWM29546.1 - 0.95 9.3 5.4 1.2 9.0 5.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RAP1 PF07218.11 EWM29546.1 - 5 5.3 7.5 5.9 5.0 7.5 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pkinase PF00069.25 EWM29547.1 - 2.5e-64 217.2 0.0 3.4e-64 216.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM29547.1 - 2.1e-44 151.8 0.0 3.1e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EWM29547.1 - 2.7e-06 26.9 0.0 0.0011 18.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EWM29547.1 - 1.3e-05 24.2 0.1 3.5e-05 22.8 0.1 1.6 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EWM29547.1 - 0.001 18.5 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EWM29547.1 - 0.0053 16.7 0.4 2 8.3 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Sugar_tr PF00083.24 EWM29548.1 - 1.1e-35 123.4 24.0 5.5e-24 84.8 7.7 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EWM29548.1 - 5e-26 91.5 42.9 2.8e-24 85.7 25.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EWM29548.1 - 9.7e-05 21.1 19.7 0.082 11.4 1.3 2.9 1 1 1 2 2 2 2 MFS/sugar transport protein BT1 PF03092.16 EWM29548.1 - 0.0038 15.5 0.3 0.012 13.8 0.1 1.9 2 0 0 2 2 2 1 BT1 family Haem_degrading PF03928.14 EWM29549.1 - 1.8e-27 95.7 0.1 2.1e-27 95.5 0.1 1.0 1 0 0 1 1 1 1 Haem-degrading Ig_C17orf99 PF17736.1 EWM29549.1 - 0.14 12.2 0.1 0.21 11.6 0.1 1.2 1 0 0 1 1 1 0 C17orf99 Ig domain DUF1937 PF09152.10 EWM29549.1 - 0.17 12.7 0.1 0.28 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1937) DUF872 PF05915.12 EWM29550.1 - 0.27 11.4 1.3 0.56 10.4 0.9 1.8 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) DUF4718 PF15842.5 EWM29550.1 - 1.7 8.4 8.9 3.7 7.3 8.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) DUF872 PF05915.12 EWM29551.1 - 0.27 11.4 1.3 0.56 10.4 0.9 1.8 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) DUF4718 PF15842.5 EWM29551.1 - 1.7 8.4 8.9 3.7 7.3 8.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) NUDIX PF00293.28 EWM29552.1 - 1.5e-14 54.2 0.1 4.8e-14 52.5 0.1 1.8 1 0 0 1 1 1 1 NUDIX domain Herpes_MCP PF03122.14 EWM29552.1 - 0.13 9.7 0.0 0.18 9.2 0.0 1.0 1 0 0 1 1 1 0 Herpes virus major capsid protein AAA_28 PF13521.6 EWM29553.1 - 9e-21 74.8 0.0 1.2e-20 74.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain DAP3 PF10236.9 EWM29553.1 - 0.0007 18.9 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_30 PF13604.6 EWM29553.1 - 0.017 14.9 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 EWM29553.1 - 0.026 14.0 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 LRR_8 PF13855.6 EWM29554.1 - 1.1e-24 85.9 20.0 1.5e-06 27.9 0.2 4.7 3 1 0 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 EWM29554.1 - 7.3e-19 67.6 15.6 5.9e-05 23.4 0.5 6.3 3 2 4 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EWM29554.1 - 1.7e-11 43.0 16.7 1.3 9.8 0.1 9.3 9 0 0 9 9 9 4 Leucine Rich Repeat LRR_6 PF13516.6 EWM29554.1 - 8e-09 34.9 8.9 3.1 8.1 0.0 8.2 9 0 0 9 9 9 4 Leucine Rich repeat LRR_2 PF07723.13 EWM29554.1 - 0.23 12.2 2.0 1.1e+02 3.8 0.0 4.5 5 0 0 5 5 5 0 Leucine Rich Repeat p450 PF00067.22 EWM29556.1 - 4.8e-77 259.7 0.0 6.9e-77 259.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 NYN PF01936.18 EWM29557.1 - 0.016 15.7 0.5 0.085 13.3 0.0 2.3 3 0 0 3 3 3 0 NYN domain ECH_1 PF00378.20 EWM29558.1 - 1.2e-36 126.4 0.0 1.5e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EWM29558.1 - 3.4e-14 53.1 0.0 1.2e-13 51.3 0.0 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_C50 PF03568.17 EWM29559.1 - 4.8e-34 118.2 0.0 2.1e-19 70.0 0.0 2.1 2 0 0 2 2 2 2 Peptidase family C50 CHAT PF12770.7 EWM29559.1 - 1.1e-05 25.0 0.0 0.00014 21.4 0.0 2.3 1 1 0 1 1 1 1 CHAT domain Pantoate_transf PF02548.15 EWM29560.1 - 6.4e-108 360.0 0.9 6.4e-108 360.0 0.9 1.4 2 0 0 2 2 2 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 EWM29560.1 - 0.00017 21.1 0.4 0.00044 19.8 0.4 1.7 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Asp_Glu_race PF01177.22 EWM29560.1 - 0.021 14.7 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 Asp/Glu/Hydantoin racemase Glutaredoxin PF00462.24 EWM29561.1 - 6.7e-17 61.5 0.0 1.2e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin CA_like PF10563.9 EWM29561.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 1 0 1 1 1 0 Putative carbonic anhydrase Kinesin PF00225.23 EWM29562.1 - 2.1e-23 82.8 0.0 9.2e-19 67.5 0.0 3.0 3 0 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 EWM29562.1 - 6.8e-05 22.8 0.0 0.0013 18.7 0.0 2.5 2 0 0 2 2 2 1 Microtubule binding ICAM_N PF03921.14 EWM29562.1 - 0.063 13.0 1.4 0.15 11.8 1.4 1.6 1 0 0 1 1 1 0 Intercellular adhesion molecule (ICAM), N-terminal domain DUF4446 PF14584.6 EWM29562.1 - 9.7 6.2 13.2 0.43 10.6 1.5 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) PPR_2 PF13041.6 EWM29563.1 - 7.1e-55 183.0 0.1 8e-11 42.0 0.0 14.2 9 4 5 14 14 14 10 PPR repeat family PPR_3 PF13812.6 EWM29563.1 - 8.4e-45 150.7 0.0 1.7e-09 37.6 0.0 9.3 10 1 0 10 10 10 6 Pentatricopeptide repeat domain PPR_1 PF12854.7 EWM29563.1 - 1.3e-39 133.6 2.2 6.9e-08 32.1 0.0 12.4 13 0 0 13 13 13 6 PPR repeat PPR PF01535.20 EWM29563.1 - 3.7e-33 111.4 14.1 0.00014 21.8 0.0 13.6 15 0 0 15 15 15 8 PPR repeat PPR_long PF17177.4 EWM29563.1 - 3.8e-19 68.9 0.8 2.3e-07 30.4 0.0 5.5 4 1 1 6 6 6 3 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 EWM29563.1 - 0.00021 21.9 6.1 6 8.0 0.2 6.4 6 0 0 6 6 5 1 Tetratricopeptide repeat BTAD PF03704.17 EWM29563.1 - 0.00042 20.8 3.8 3.6 8.0 0.1 4.8 4 1 1 5 5 5 1 Bacterial transcriptional activator domain ECSIT PF06239.11 EWM29563.1 - 0.00051 19.2 0.0 9.7 5.2 0.0 4.0 3 1 1 4 4 4 1 Evolutionarily conserved signalling intermediate in Toll pathway TPR_7 PF13176.6 EWM29563.1 - 0.0056 16.6 0.7 1.8 8.7 0.1 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat RPM2 PF08579.11 EWM29563.1 - 0.12 12.8 0.0 2.7 8.4 0.0 3.0 3 1 0 3 3 3 0 Mitochondrial ribonuclease P subunit (RPM2) TPR_2 PF07719.17 EWM29563.1 - 2 8.8 5.3 21 5.6 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 EWM29563.1 - 9.8 7.1 13.5 7.5 7.5 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat SNase PF00565.17 EWM29564.1 - 5.6e-20 71.8 0.0 9.9e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Staphylococcal nuclease homologue DUF1658 PF07871.11 EWM29564.1 - 0.1 12.6 0.8 0.42 10.6 0.8 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1658) ORC2 PF04084.14 EWM29565.1 - 4.3e-58 196.8 0.0 7.1e-58 196.1 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex subunit 2 DUF1707 PF08044.11 EWM29565.1 - 0.018 15.1 1.0 0.071 13.2 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) TFIIA PF03153.13 EWM29566.1 - 0.13 12.2 8.2 0.21 11.6 8.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Bromodomain PF00439.25 EWM29567.1 - 9.6e-10 38.4 0.0 1.8e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Bromodomain WSD PF15613.6 EWM29567.1 - 2.3e-08 34.4 0.0 2.3e-08 34.4 0.0 6.1 6 0 0 6 6 6 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif FYRN PF05964.14 EWM29567.1 - 0.00012 21.9 0.0 0.00026 20.8 0.0 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus PHD PF00628.29 EWM29567.1 - 0.00028 20.7 5.4 0.00091 19.1 5.4 2.0 1 0 0 1 1 1 1 PHD-finger FYRC PF05965.14 EWM29567.1 - 0.052 13.7 2.1 0.24 11.6 0.0 2.9 3 0 0 3 3 3 0 F/Y rich C-terminus Velvet PF11754.8 EWM29567.1 - 4.3 7.2 16.5 17 5.2 16.5 2.0 1 0 0 1 1 1 0 Velvet factor Choline_transpo PF04515.12 EWM29568.1 - 2e-60 204.8 15.7 2e-60 204.8 15.7 2.1 2 1 0 2 2 2 1 Plasma-membrane choline transporter Stm1_N PF09598.10 EWM29568.1 - 4.1 8.3 6.5 6.9 7.6 5.7 1.7 1 1 0 1 1 1 0 Stm1 PDDEXK_1 PF12705.7 EWM29569.1 - 3.3e-38 132.1 0.0 3.9e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.17 EWM29569.1 - 3.4e-05 24.0 0.0 0.0026 17.9 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function DUF83 Dna2 PF08696.11 EWM29569.1 - 0.00019 21.3 0.0 0.00029 20.7 0.0 1.2 1 0 0 1 1 1 1 DNA replication factor Dna2 PDDEXK_1 PF12705.7 EWM29570.1 - 1.1e-28 100.8 0.0 1.5e-28 100.4 0.0 1.1 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Dna2 PF08696.11 EWM29570.1 - 0.00021 21.2 0.0 0.00031 20.6 0.0 1.2 1 0 0 1 1 1 1 DNA replication factor Dna2 Cas_Cas4 PF01930.17 EWM29570.1 - 0.075 13.1 0.0 5.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF83 CaMKII_AD PF08332.10 EWM29571.1 - 6.1e-11 42.6 0.0 1.2e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain OTU PF02338.19 EWM29571.1 - 8.8e-11 42.4 0.0 1.7e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease DUF4440 PF14534.6 EWM29571.1 - 1.4e-10 41.6 0.1 2.8e-10 40.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 EWM29571.1 - 1.1e-06 28.8 0.0 3.8e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 SnoaL-like domain MatE PF01554.18 EWM29576.1 - 3.4e-25 88.6 33.1 7.8e-17 61.4 8.2 3.0 3 1 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 EWM29576.1 - 4.1e-06 26.9 3.5 4.1e-06 26.9 3.5 4.3 2 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain PolyA_pol PF01743.20 EWM29577.1 - 8.5e-26 90.9 0.0 2.4e-25 89.4 0.0 1.8 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EWM29577.1 - 0.0044 16.8 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A F-box-like PF12937.7 EWM29578.1 - 0.00094 19.0 0.4 0.0026 17.6 0.4 1.8 1 0 0 1 1 1 1 F-box-like zf-CCCH PF00642.24 EWM29578.1 - 0.015 15.2 1.3 0.049 13.6 1.3 1.9 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) WD40 PF00400.32 EWM29578.1 - 0.28 12.1 2.2 0.76 10.8 0.1 2.9 2 0 0 2 2 2 0 WD domain, G-beta repeat MMR_HSR1 PF01926.23 EWM29579.1 - 8e-12 45.3 0.0 9.9e-11 41.7 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EWM29579.1 - 8.4e-07 29.0 0.0 0.00023 21.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EWM29579.1 - 0.003 17.1 0.0 0.014 14.9 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B PhoLip_ATPase_C PF16212.5 EWM29580.1 - 1e-64 218.7 5.5 1e-64 218.7 5.5 2.3 3 1 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EWM29580.1 - 2.8e-21 75.0 0.4 9.3e-21 73.3 0.4 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EWM29580.1 - 1.4e-11 44.4 0.0 1.1e-10 41.4 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EWM29580.1 - 8.2e-10 39.3 5.2 0.00014 22.2 2.9 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EWM29580.1 - 1.4e-06 28.0 0.1 3.3e-05 23.5 0.0 2.9 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EWM29580.1 - 0.002 17.9 0.0 0.0078 16.0 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EWM29580.1 - 0.0028 18.1 0.1 0.4 11.1 0.1 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF5316 PF17247.2 EWM29581.1 - 0.012 15.6 0.0 3.3 7.8 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5316) Sld5 PF05916.11 EWM29582.1 - 3.1e-08 34.0 0.0 4.6e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Helicase_C_2 PF13307.6 EWM29583.1 - 2.7e-51 174.2 0.0 5.3e-51 173.2 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 EWM29583.1 - 1.9e-46 157.9 0.0 3.5e-46 157.0 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 EWM29583.1 - 0.00013 22.1 0.0 0.071 13.1 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 EWM29583.1 - 0.00048 19.9 5.6 0.0011 18.7 5.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EWM29583.1 - 0.00064 19.5 5.2 0.0016 18.2 5.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EWM29583.1 - 0.00089 19.1 3.8 0.0024 17.7 3.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EWM29583.1 - 0.0028 17.6 4.0 0.0071 16.3 4.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger DEAD PF00270.29 EWM29583.1 - 0.0083 15.9 0.0 0.9 9.3 0.0 2.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase zf-RING_2 PF13639.6 EWM29583.1 - 1.3 9.5 15.5 0.047 14.0 9.3 1.9 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.6 EWM29583.1 - 3.1 7.8 9.1 57 3.8 8.6 2.5 1 1 1 2 2 2 0 zinc-RING finger domain Beta-lactamase PF00144.24 EWM29584.1 - 4.6e-22 78.7 0.1 1.1e-21 77.4 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase Band_7 PF01145.25 EWM29585.1 - 9.7e-30 103.9 0.0 2e-29 102.9 0.0 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 EWM29585.1 - 3.5e-13 49.4 0.4 7.5e-13 48.3 0.4 1.6 1 0 0 1 1 1 1 C-terminal region of band_7 Band_7_1 PF13421.6 EWM29585.1 - 0.02 14.6 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family Flot PF15975.5 EWM29585.1 - 7.9 6.7 11.2 14 5.9 6.0 2.7 1 1 1 2 2 2 0 Flotillin PCRF PF03462.18 EWM29586.1 - 1.2e-53 181.9 0.2 1.2e-53 181.9 0.2 1.8 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 EWM29586.1 - 1.3e-38 131.5 2.0 3e-38 130.3 2.0 1.7 1 0 0 1 1 1 1 RF-1 domain DUF2730 PF10805.8 EWM29586.1 - 0.06 13.5 0.3 22 5.2 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) Queuosine_synth PF02547.15 EWM29587.1 - 1.3e-92 310.4 0.0 1.3e-67 228.3 0.0 2.0 2 0 0 2 2 2 2 Queuosine biosynthesis protein PKD_channel PF08016.12 EWM29587.1 - 0.083 11.5 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Polycystin cation channel Rsm22 PF09243.10 EWM29591.1 - 1.4e-42 145.9 0.0 7.4e-42 143.5 0.0 1.9 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 EWM29591.1 - 3.8e-05 23.6 0.0 8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM29591.1 - 0.00038 21.1 0.0 0.00079 20.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM29591.1 - 0.013 16.1 0.0 0.045 14.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EWM29591.1 - 0.12 13.2 0.0 0.25 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EWM29591.1 - 0.17 11.7 0.0 0.91 9.3 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain RGS PF00615.19 EWM29592.1 - 1.2e-17 64.3 0.0 5.1e-15 55.8 0.0 3.2 3 0 0 3 3 3 2 Regulator of G protein signaling domain DENN PF02141.21 EWM29592.1 - 1.4e-10 41.4 2.0 2.1e-10 40.8 0.4 2.1 2 0 0 2 2 2 1 DENN (AEX-3) domain dDENN PF03455.19 EWM29592.1 - 0.044 13.8 1.3 0.12 12.4 1.3 1.7 1 0 0 1 1 1 0 dDENN domain Bin3 PF06859.12 EWM29593.1 - 4.3e-33 114.2 0.0 7.3e-33 113.4 0.0 1.4 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_23 PF13489.6 EWM29593.1 - 1.1e-11 44.8 0.0 2e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM29593.1 - 2.8e-09 37.0 0.0 2.4e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EWM29593.1 - 2.8e-09 37.6 0.0 0.00093 19.9 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 EWM29593.1 - 6.7e-09 36.3 0.0 0.00014 22.5 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EWM29593.1 - 5.1e-08 33.5 0.0 0.0049 17.5 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 EWM29593.1 - 0.057 12.8 0.0 0.28 10.5 0.0 1.9 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 EWM29593.1 - 0.077 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 EWM29595.1 - 1.3e-27 96.8 0.0 1.2e-19 70.7 0.0 2.2 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Amino_oxidase PF01593.24 EWM29595.1 - 3.4e-19 69.5 0.0 2.1e-16 60.3 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EWM29595.1 - 1.7e-10 40.9 0.1 3.6e-10 39.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Methyltransf_25 PF13649.6 EWM29595.1 - 0.00046 20.8 0.0 0.0016 19.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_9 PF13454.6 EWM29595.1 - 0.00047 20.2 0.3 0.0039 17.2 0.0 2.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding DOT1 PF08123.13 EWM29595.1 - 0.00065 19.3 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 DAO PF01266.24 EWM29595.1 - 0.0009 18.9 0.8 0.0021 17.7 0.8 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase MCRA PF06100.11 EWM29595.1 - 0.0023 16.8 0.0 0.0033 16.3 0.0 1.2 1 0 0 1 1 1 1 MCRA family Methyltransf_11 PF08241.12 EWM29595.1 - 0.0043 17.7 0.0 0.013 16.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Pyr_redox_2 PF07992.14 EWM29595.1 - 0.016 14.4 0.2 0.071 12.3 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EWM29595.1 - 0.027 13.6 0.2 1.2 8.2 0.0 2.5 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EWM29595.1 - 0.086 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 EWM29595.1 - 0.45 11.1 1.8 25 5.5 0.3 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Gal-3-0_sulfotr PF06990.11 EWM29597.1 - 8.7e-08 31.4 0.3 0.0027 16.6 0.2 2.1 1 1 1 2 2 2 2 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 EWM29597.1 - 9.2e-05 22.5 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family DUF4490 PF14892.6 EWM29598.1 - 2.2e-10 40.5 1.2 2.6e-10 40.3 1.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) GPI2 PF06432.11 EWM29599.1 - 2.7e-65 220.6 1.4 4.9e-65 219.8 1.4 1.4 1 1 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase HECT PF00632.25 EWM29600.1 - 9.9e-86 288.0 0.0 1.4e-85 287.5 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Hydrolase_6 PF13344.6 EWM29601.1 - 1.8e-30 105.0 0.0 3.3e-30 104.2 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EWM29601.1 - 1.2e-19 70.2 0.0 3.2e-19 68.7 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 EWM29601.1 - 1.4e-12 48.4 0.1 1.2e-10 42.1 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EWM29601.1 - 6e-07 29.7 0.3 0.00086 19.4 0.0 2.6 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 EWM29601.1 - 0.0061 16.2 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase DUF2608 PF11019.8 EWM29601.1 - 0.036 13.6 0.0 0.057 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) Gtr1_RagA PF04670.12 EWM29602.1 - 2.9e-95 318.0 0.3 4e-95 317.6 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 EWM29602.1 - 2.6e-09 36.8 0.0 6.5e-09 35.5 0.0 1.7 1 1 1 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 EWM29602.1 - 3e-09 37.1 0.0 3.9e-08 33.5 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EWM29602.1 - 6.9e-09 35.5 0.1 1.5e-08 34.4 0.0 1.6 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.23 EWM29602.1 - 0.00039 20.5 0.0 0.00072 19.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EWM29602.1 - 0.031 14.0 0.1 0.088 12.6 0.1 1.8 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 EWM29602.1 - 0.037 13.9 0.1 2.3 8.1 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 EWM29602.1 - 0.092 13.3 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter DUF815 PF05673.13 EWM29602.1 - 0.1 11.8 0.0 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) G-alpha PF00503.20 EWM29602.1 - 0.22 10.7 3.4 7.1 5.7 0.0 2.5 1 1 1 2 2 2 0 G-protein alpha subunit HSP90 PF00183.18 EWM29604.1 - 7.1e-233 774.2 23.7 7.1e-233 774.2 23.7 1.4 2 0 0 2 2 2 1 Hsp90 protein HATPase_c PF02518.26 EWM29604.1 - 3.3e-15 56.6 0.1 7.7e-15 55.4 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EWM29604.1 - 2.8e-11 43.4 0.1 9.7e-11 41.6 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glutaredoxin2_C PF04399.13 EWM29604.1 - 0.19 11.5 2.6 0.52 10.2 0.1 2.9 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain DUF2052 PF09747.9 EWM29604.1 - 5.8 7.0 18.9 0.27 11.3 10.9 2.3 2 1 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Tau95 PF09734.9 EWM29604.1 - 6.2 7.6 7.1 14 6.5 2.6 2.8 3 0 0 3 3 3 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain SpoU_methylase PF00588.19 EWM29606.1 - 9.3e-27 93.9 0.0 1.4e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family CRAL_TRIO PF00650.20 EWM29608.1 - 7.7e-22 77.7 0.0 1.2e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EWM29608.1 - 2.6e-07 30.9 0.0 4e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain TPT PF03151.16 EWM29609.1 - 4.5e-89 298.7 11.9 5.9e-89 298.2 11.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EWM29609.1 - 6.9e-09 36.0 25.5 4.6e-06 26.8 6.5 2.5 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EWM29609.1 - 0.0026 17.0 0.8 0.0026 17.0 0.8 2.9 2 1 1 4 4 4 1 UAA transporter family Ribosomal_L34e PF01199.18 EWM29610.1 - 2.5e-39 133.5 6.1 3.4e-39 133.1 6.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e Spermine_synth PF01564.17 EWM29611.1 - 5.2e-66 221.7 0.0 1.4e-65 220.3 0.0 1.6 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 EWM29611.1 - 6.2e-22 77.2 0.1 1e-21 76.5 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 EWM29611.1 - 7.5e-05 23.4 0.1 0.00028 21.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_30 PF05430.11 EWM29611.1 - 0.011 15.6 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.12 EWM29611.1 - 0.013 16.2 0.0 0.06 14.1 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EWM29611.1 - 0.13 11.8 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain zf-C3HC4_3 PF13920.6 EWM29613.1 - 8.4e-09 35.2 9.0 2.5e-08 33.6 9.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EWM29613.1 - 0.00013 21.8 10.1 0.00039 20.2 10.1 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 HATPase_c_3 PF13589.6 EWM29613.1 - 0.0053 16.6 0.1 1.7 8.5 0.0 3.6 2 2 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UBA PF00627.31 EWM29613.1 - 0.011 15.6 0.0 0.065 13.2 0.0 2.3 2 0 0 2 2 2 0 UBA/TS-N domain zf-C3HC4_2 PF13923.6 EWM29613.1 - 0.072 12.9 11.5 0.24 11.3 11.5 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EWM29613.1 - 0.21 11.7 9.1 0.84 9.7 9.1 2.2 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 EWM29613.1 - 0.31 11.0 12.2 0.94 9.5 12.2 1.9 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 EWM29613.1 - 0.31 10.9 13.6 0.37 10.7 11.8 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF2039 PF10217.9 EWM29613.1 - 2.5 8.5 5.4 5.3 7.5 5.4 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) SDP_N PF12278.8 EWM29614.1 - 6.7 6.9 8.1 0.52 10.4 1.6 2.3 2 0 0 2 2 2 0 Sex determination protein N terminal DENN PF02141.21 EWM29615.1 - 2e-36 125.7 0.3 4.5e-36 124.5 0.3 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 EWM29615.1 - 8.9e-12 44.8 1.1 2.1e-11 43.6 1.1 1.7 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.18 EWM29615.1 - 2e-10 41.3 0.1 5.5e-10 39.8 0.1 1.8 1 0 0 1 1 1 1 uDENN domain DUF2464 PF10240.9 EWM29615.1 - 4.4e-09 36.3 0.0 1.2e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 Multivesicular body subunit 12 PPR_2 PF13041.6 EWM29615.1 - 0.035 14.3 0.0 2.3 8.5 0.0 2.5 2 0 0 2 2 2 0 PPR repeat family CpXC PF14353.6 EWM29615.1 - 0.085 12.9 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 CpXC protein Tma16 PF11176.8 EWM29615.1 - 2 8.3 4.5 8.5 6.2 0.1 3.2 4 0 0 4 4 4 0 Translation machinery-associated protein 16 Bestrophin PF01062.21 EWM29617.1 - 4.9e-38 131.2 1.8 1.2e-37 129.9 0.7 1.8 2 0 0 2 2 2 1 Bestrophin, RFP-TM, chloride channel RNA_pol_Rpb1_5 PF04998.17 EWM29618.1 - 1.5e-88 296.7 0.0 2.6e-88 295.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 EWM29618.1 - 4.6e-84 282.4 0.0 8.5e-84 281.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 EWM29618.1 - 1.4e-76 256.4 0.1 2.4e-76 255.6 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 EWM29618.1 - 6.8e-54 182.6 0.0 1.1e-53 181.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 EWM29618.1 - 2.5e-48 164.0 0.0 5.8e-48 162.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EWM29618.1 - 3.5e-34 117.0 0.0 6.7e-34 116.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_7 PF04990.12 EWM29618.1 - 4.6e-25 88.2 0.4 9.4e-25 87.2 0.4 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 HTH_29 PF13551.6 EWM29618.1 - 0.1 12.6 0.0 12 6.1 0.0 3.0 3 0 0 3 3 3 0 Winged helix-turn helix Peptidase_C48 PF02902.19 EWM29619.1 - 6.2e-08 32.7 0.0 1.1e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain CENP-T_C PF15511.6 EWM29620.1 - 5.2e-08 33.0 0.0 6.7e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EWM29620.1 - 0.00058 20.2 0.1 0.00083 19.7 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 EWM29620.1 - 0.00091 19.4 0.1 0.0013 18.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EWM29620.1 - 0.0064 16.8 0.0 0.011 16.0 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EWM29620.1 - 0.013 15.9 0.2 0.016 15.5 0.1 1.3 1 1 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EWM29620.1 - 0.08 13.0 0.0 0.096 12.8 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EWM29620.1 - 0.15 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated RSN1_7TM PF02714.15 EWM29621.1 - 3.3e-46 157.8 20.5 7.3e-46 156.7 18.5 2.1 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EWM29621.1 - 2.9e-31 108.4 0.5 2.9e-31 108.4 0.5 2.1 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EWM29621.1 - 1.2e-21 77.7 0.0 2.7e-12 47.3 0.0 2.2 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter Anoctamin PF04547.12 EWM29621.1 - 0.0025 16.7 4.2 0.013 14.4 4.1 1.9 1 1 0 1 1 1 1 Calcium-activated chloride channel SlyX PF04102.12 EWM29621.1 - 2.1 9.1 3.9 1 10.0 1.3 1.8 2 0 0 2 2 2 0 SlyX Ribosomal_S21e PF01249.18 EWM29622.1 - 7.1e-35 119.0 0.3 8.3e-35 118.8 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e TBPIP PF07106.13 EWM29623.1 - 0.15 12.0 0.1 0.31 11.0 0.1 1.5 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain Pyr_redox_2 PF07992.14 EWM29624.1 - 7e-68 229.0 5.7 7e-68 229.0 5.7 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EWM29624.1 - 2.4e-38 130.8 3.2 1.2e-37 128.5 0.1 2.8 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EWM29624.1 - 5.9e-22 78.0 10.2 7.1e-21 74.6 0.2 4.1 3 1 3 6 6 6 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EWM29624.1 - 7.6e-09 35.4 1.1 2.8e-08 33.5 0.5 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 EWM29624.1 - 5.1e-07 29.1 5.6 7.2e-06 25.3 3.4 2.4 2 1 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EWM29624.1 - 3.4e-06 27.2 2.3 0.0081 16.4 0.4 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 EWM29624.1 - 0.0006 19.2 6.5 0.01 15.1 0.3 2.8 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 EWM29624.1 - 0.0007 18.8 3.6 0.0007 18.8 3.6 2.8 3 1 0 3 3 3 1 FAD binding domain K_oxygenase PF13434.6 EWM29624.1 - 0.0027 16.9 0.2 0.033 13.3 0.0 2.5 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EWM29624.1 - 0.0048 16.2 2.2 0.012 14.8 0.2 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 EWM29624.1 - 0.013 14.7 7.4 0.093 12.0 0.2 2.9 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EWM29624.1 - 0.019 13.7 11.1 0.32 9.7 2.1 3.7 2 1 2 4 4 4 0 HI0933-like protein FAD_binding_3 PF01494.19 EWM29624.1 - 0.078 12.2 10.3 2.7 7.1 1.4 3.5 2 1 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.18 EWM29624.1 - 0.079 12.8 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1415 PF07209.12 EWM29625.1 - 2.9e-39 134.5 0.0 2.9e-39 134.5 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1415) PPP1R32 PF15691.5 EWM29625.1 - 0.00082 18.6 0.1 0.0014 17.9 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 1 regulatory subunit 32 adh_short_C2 PF13561.6 EWM29626.1 - 1.3e-62 211.4 0.3 1.6e-62 211.1 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EWM29626.1 - 2.3e-54 183.9 0.3 2.7e-54 183.6 0.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EWM29626.1 - 2.4e-13 50.4 0.6 3.1e-13 50.0 0.6 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EWM29626.1 - 0.0011 18.5 0.1 0.0042 16.6 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family bVLRF1 PF18826.1 EWM29626.1 - 0.0087 15.9 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor NAD_binding_4 PF07993.12 EWM29626.1 - 0.037 13.2 0.1 0.15 11.2 0.1 1.9 1 1 0 1 1 1 0 Male sterility protein HAD_2 PF13419.6 EWM29627.1 - 5.5e-17 62.4 0.0 1.7e-16 60.8 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EWM29627.1 - 2.6e-07 31.1 0.0 0.0012 19.2 0.0 2.5 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EWM29627.1 - 3.1e-05 24.5 0.0 3.5e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.18 EWM29627.1 - 0.00058 19.7 0.0 0.0033 17.2 0.0 2.0 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Linker_histone PF00538.19 EWM29629.1 - 2.4e-12 47.1 0.0 2.4e-12 47.1 0.0 2.6 3 0 0 3 3 3 1 linker histone H1 and H5 family Str_synth PF03088.16 EWM29629.1 - 0.032 14.3 0.0 0.063 13.4 0.0 1.5 1 0 0 1 1 1 0 Strictosidine synthase Mitofilin PF09731.9 EWM29629.1 - 1.3 7.8 30.3 1.4 7.7 30.3 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Phytochelatin PF05023.14 EWM29630.1 - 5.8e-84 280.6 0.0 7.1e-83 277.0 0.0 2.2 1 1 0 1 1 1 1 Phytochelatin synthase Acetyltransf_10 PF13673.7 EWM29631.1 - 4e-09 36.5 0.0 6.4e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EWM29631.1 - 1.5e-06 28.4 0.7 3.1e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EWM29631.1 - 6.9e-05 23.2 0.1 6.9e-05 23.2 0.1 2.3 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EWM29631.1 - 0.0002 21.3 0.0 0.00051 20.0 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Pyr_redox_2 PF07992.14 EWM29632.1 - 3.9e-41 141.2 0.0 1.4e-40 139.4 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EWM29632.1 - 1.2e-05 25.7 0.0 0.00032 21.2 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase MA3 PF02847.17 EWM29633.1 - 1.4e-18 66.9 0.7 5.5e-18 65.0 0.1 2.4 3 1 0 3 3 3 1 MA3 domain MIF4G PF02854.19 EWM29633.1 - 1.9e-18 66.9 0.2 1e-16 61.3 0.0 2.9 4 0 0 4 4 4 1 MIF4G domain DUF4637 PF15470.6 EWM29633.1 - 0.67 9.7 23.5 1.7 8.3 23.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) BUD22 PF09073.10 EWM29633.1 - 1.9 7.7 18.5 3.7 6.8 18.5 1.4 1 0 0 1 1 1 0 BUD22 Zip PF02535.22 EWM29633.1 - 2.2 7.4 3.6 4.2 6.5 3.6 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 EWM29633.1 - 5.2 5.2 18.7 11 4.2 18.7 1.4 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 EWM29633.1 - 6.1 6.2 26.2 13 5.1 26.2 1.5 1 0 0 1 1 1 0 SDA1 RraA-like PF03737.15 EWM29634.1 - 5.5e-45 153.2 0.3 7e-45 152.9 0.3 1.1 1 0 0 1 1 1 1 Aldolase/RraA Cyt-b5 PF00173.28 EWM29635.1 - 1.6e-24 85.8 0.1 4.6e-13 49.1 0.1 2.4 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain PsbU PF06514.11 EWM29635.1 - 0.066 13.2 0.0 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 Photosystem II 12 kDa extrinsic protein (PsbU) GA PF01468.17 EWM29635.1 - 0.11 12.8 0.0 3 8.2 0.0 2.3 2 0 0 2 2 2 0 GA module Exo_endo_phos PF03372.23 EWM29636.1 - 3.3e-25 89.0 0.1 7.9e-25 87.7 0.1 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-C6H2 PF15801.5 EWM29636.1 - 2.5e-08 34.1 9.0 6.7e-08 32.7 9.0 1.8 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding ATP-synt_F PF01990.17 EWM29637.1 - 1.4e-33 115.1 0.1 1.6e-33 114.9 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DXP_synthase_N PF13292.6 EWM29637.1 - 0.043 13.0 0.0 0.043 13.0 0.0 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase DHQS PF01959.16 EWM29638.1 - 7.4e-78 261.9 1.7 6.4e-64 216.1 0.4 2.0 1 1 1 2 2 2 2 3-dehydroquinate synthase II Hint PF01079.20 EWM29638.1 - 0.027 14.0 0.1 0.1 12.1 0.0 1.8 2 0 0 2 2 2 0 Hint module PUA PF01472.20 EWM29638.1 - 0.071 13.1 0.2 3.9 7.5 0.1 2.8 3 0 0 3 3 3 0 PUA domain CH_2 PF06294.11 EWM29639.1 - 1.9e-28 98.4 0.0 3.7e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 EWM29639.1 - 5.4e-09 35.8 0.0 8.4e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 CAMSAP CH domain ATG16 PF08614.11 EWM29639.1 - 0.00088 19.6 0.1 0.0016 18.7 0.1 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Adeno_E1B_19K PF01691.16 EWM29639.1 - 0.15 11.6 0.1 0.32 10.5 0.1 1.5 1 0 0 1 1 1 0 Adenovirus E1B 19K protein / small t-antigen Tcp11 PF05794.13 EWM29640.1 - 3.1e-40 138.6 1.0 7.1e-40 137.4 1.0 1.6 1 0 0 1 1 1 1 T-complex protein 11 Pescadillo_N PF06732.11 EWM29641.1 - 2.1e-104 348.9 0.0 2.9e-104 348.4 0.0 1.1 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT_2 PF16589.5 EWM29641.1 - 9.5e-07 29.2 0.0 1.6e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RPE65 PF03055.15 EWM29642.1 - 4e-66 224.1 0.0 4.7e-66 223.9 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein TspO_MBR PF03073.15 EWM29643.1 - 1.1e-23 83.8 15.5 1.1e-23 83.8 15.5 1.7 2 0 0 2 2 2 1 TspO/MBR family Zip PF02535.22 EWM29643.1 - 0.039 13.2 0.8 0.061 12.5 0.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 EWM29643.1 - 0.062 13.1 5.9 0.089 12.6 5.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3827 PF12877.7 EWM29643.1 - 0.13 10.7 4.3 0.16 10.3 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) SID-1_RNA_chan PF13965.6 EWM29643.1 - 0.14 10.5 0.1 0.23 9.8 0.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 G0-G1_switch_2 PF15103.6 EWM29643.1 - 0.25 11.8 7.0 1.1 9.7 7.0 1.9 1 1 0 1 1 1 0 G0/G1 switch protein 2 DUF5427 PF10310.9 EWM29643.1 - 0.81 8.6 10.0 1.1 8.1 10.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Phage_holin_2_4 PF16082.5 EWM29643.1 - 4.5 7.1 0.0 4.5 7.1 0.0 3.1 2 1 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Presenilin PF01080.17 EWM29643.1 - 7.9 5.1 9.5 0.17 10.6 3.0 1.5 2 0 0 2 2 2 0 Presenilin Histone_H2A_C PF16211.5 EWM29644.1 - 1.1e-20 73.0 1.8 1.8e-20 72.3 1.8 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EWM29644.1 - 8.8e-15 55.2 0.0 1.1e-14 55.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EWM29644.1 - 0.00013 22.2 0.0 0.00017 21.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone NDUF_B7 PF05676.13 EWM29645.1 - 2.1e-27 94.6 3.8 2.3e-27 94.5 3.8 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 EWM29645.1 - 0.00024 21.1 1.7 0.00027 20.9 1.4 1.3 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Yippee-Mis18 PF03226.14 EWM29646.1 - 1.7e-21 76.4 0.0 2.5e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TraB PF01963.17 EWM29647.1 - 2.4e-08 34.2 0.4 0.001 19.0 0.0 2.2 2 0 0 2 2 2 2 TraB family His_Phos_1 PF00300.22 EWM29648.1 - 6.3e-48 163.0 0.2 6.2e-19 68.4 0.0 3.1 2 1 1 3 3 3 3 Histidine phosphatase superfamily (branch 1) PDZ_3 PF17815.1 EWM29652.1 - 1e-37 129.2 0.0 1.5e-37 128.7 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Trypsin_2 PF13365.6 EWM29652.1 - 5.9e-20 72.7 0.1 1.1e-19 71.9 0.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 EWM29652.1 - 2.1e-12 47.3 0.0 3.6e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 EWM29652.1 - 1.1e-07 32.0 0.0 3.3e-06 27.3 0.0 2.5 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EWM29652.1 - 0.00092 19.0 0.1 0.13 12.1 0.1 2.6 2 0 0 2 2 2 1 PDZ domain Peptidase_S46 PF10459.9 EWM29652.1 - 0.0011 17.7 0.1 0.0016 17.2 0.1 1.1 1 0 0 1 1 1 1 Peptidase S46 Peptidase_S7 PF00949.21 EWM29652.1 - 0.0042 16.9 0.5 0.0092 15.8 0.5 1.5 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease PDZ PF00595.24 EWM29652.1 - 0.0046 17.3 0.0 0.019 15.3 0.0 2.0 3 0 0 3 3 3 1 PDZ domain PDZ_3 PF17815.1 EWM29653.1 - 7.5e-38 129.6 0.0 1.1e-37 129.1 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Trypsin_2 PF13365.6 EWM29653.1 - 4.5e-20 73.1 0.1 7.9e-20 72.3 0.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 EWM29653.1 - 1.5e-12 47.8 0.0 2.6e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 EWM29653.1 - 7e-08 32.7 0.0 2.5e-06 27.7 0.0 2.5 2 1 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EWM29653.1 - 0.00058 19.6 0.1 0.11 12.4 0.1 2.7 2 0 0 2 2 2 1 PDZ domain Peptidase_S46 PF10459.9 EWM29653.1 - 0.00092 18.0 0.1 0.0013 17.5 0.1 1.1 1 0 0 1 1 1 1 Peptidase S46 PDZ PF00595.24 EWM29653.1 - 0.0032 17.8 0.0 0.015 15.6 0.0 2.1 3 0 0 3 3 3 1 PDZ domain Peptidase_S7 PF00949.21 EWM29653.1 - 0.0034 17.2 0.5 0.0073 16.1 0.5 1.5 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease Branch PF02485.21 EWM29654.1 - 1.5e-24 86.9 0.0 2.9e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 Core-2/I-Branching enzyme ProRS-C_1 PF09180.11 EWM29655.1 - 4.2e-23 81.3 0.6 8.8e-23 80.3 0.6 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA_edit PF04073.15 EWM29655.1 - 4.6e-21 75.2 0.5 8.6e-21 74.3 0.5 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain tRNA-synt_2b PF00587.25 EWM29655.1 - 4e-19 69.3 0.0 6.8e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EWM29655.1 - 4.9e-18 65.1 0.1 2.4e-17 62.9 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain Histone PF00125.24 EWM29656.1 - 2.5e-52 176.7 1.5 2.8e-52 176.5 1.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EWM29656.1 - 0.00025 21.3 0.0 0.00038 20.8 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EWM29656.1 - 0.00029 20.9 0.4 0.00046 20.3 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EWM29656.1 - 0.00038 21.1 2.1 0.00048 20.7 2.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 EWM29656.1 - 0.021 15.1 0.0 0.041 14.2 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EWM29656.1 - 0.11 12.6 0.2 0.19 11.8 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Ribo_biogen_C PF04034.13 EWM29657.1 - 2e-49 166.5 0.0 2.8e-49 166.1 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 EWM29657.1 - 4.8e-13 48.7 0.1 9.9e-13 47.7 0.1 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Asparaginase_2 PF01112.18 EWM29658.1 - 4.6e-65 219.6 1.0 7.8e-65 218.9 1.0 1.3 1 1 0 1 1 1 1 Asparaginase DUF3082 PF11282.8 EWM29659.1 - 4.4e-10 39.7 4.9 6.5e-10 39.1 4.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3082) SnoaL_2 PF12680.7 EWM29660.1 - 4.9e-12 46.4 0.0 8.9e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 EWM29660.1 - 1e-06 28.5 0.2 1.8e-06 27.8 0.2 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_4 PF13577.6 EWM29660.1 - 0.059 13.5 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 SnoaL-like domain NTF2 PF02136.20 EWM29660.1 - 0.088 13.4 0.0 0.21 12.2 0.0 1.6 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain PEN-2 PF10251.9 EWM29661.1 - 6.8e-18 64.9 0.5 3e-09 37.2 0.0 2.1 2 0 0 2 2 2 2 Presenilin enhancer-2 subunit of gamma secretase DUF2207 PF09972.9 EWM29661.1 - 0.15 10.8 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TOM13 PF08219.11 EWM29661.1 - 0.23 11.4 1.5 0.41 10.6 1.5 1.4 1 0 0 1 1 1 0 Outer membrane protein TOM13 RabGAP-TBC PF00566.18 EWM29662.1 - 3.3e-39 134.8 4.5 4.5e-39 134.3 1.6 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain PDZ_6 PF17820.1 EWM29662.1 - 0.016 15.1 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 PDZ domain CM_2 PF01817.21 EWM29663.1 - 0.037 14.4 0.5 1.4 9.3 0.0 2.5 2 1 0 2 2 2 0 Chorismate mutase type II Peptidase_M41 PF01434.18 EWM29664.1 - 7.5e-42 143.3 0.4 1.3e-41 142.6 0.4 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EWM29664.1 - 1.4e-39 135.5 0.0 3.1e-39 134.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EWM29664.1 - 1.1e-12 47.5 0.0 3.6e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EWM29664.1 - 1.1e-06 29.1 0.2 7.4e-06 26.5 0.2 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EWM29664.1 - 2.2e-06 27.7 0.7 0.00052 20.0 0.1 3.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EWM29664.1 - 1.5e-05 25.2 0.1 0.029 14.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain RuvB_N PF05496.12 EWM29664.1 - 2.2e-05 24.2 0.0 5.8e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EWM29664.1 - 0.00041 19.7 0.0 0.00072 18.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 EWM29664.1 - 0.0019 18.7 0.0 0.0042 17.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EWM29664.1 - 0.0028 17.1 0.2 0.012 15.0 0.3 2.0 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EWM29664.1 - 0.0032 17.2 0.0 0.0077 16.0 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.12 EWM29664.1 - 0.004 17.1 0.0 0.027 14.4 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_2 PF07724.14 EWM29664.1 - 0.0061 16.7 0.0 0.034 14.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 EWM29664.1 - 0.0071 16.4 0.0 0.02 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EWM29664.1 - 0.02 14.6 0.0 0.069 12.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EWM29664.1 - 0.026 14.7 0.0 0.061 13.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EWM29664.1 - 0.032 13.7 0.0 0.25 10.7 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 EWM29664.1 - 0.035 13.6 0.0 0.23 11.0 0.0 2.1 1 1 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 EWM29664.1 - 0.041 14.4 0.1 0.14 12.7 0.1 2.0 1 1 0 1 1 1 0 ABC transporter TsaE PF02367.17 EWM29664.1 - 0.078 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 EWM29664.1 - 0.098 12.4 0.0 0.4 10.4 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain Glu-tRNAGln PF02686.15 EWM29665.1 - 1.7e-07 31.4 0.4 2.4e-07 30.9 0.4 1.2 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit DUF1391 PF07151.12 EWM29665.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1391) Ras PF00071.22 EWM29666.1 - 2.6e-58 196.2 0.0 2.9e-58 196.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EWM29666.1 - 6.5e-35 120.0 0.0 1e-34 119.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EWM29666.1 - 4.9e-13 48.9 0.0 5.3e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EWM29666.1 - 8e-07 29.1 0.0 0.012 15.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EWM29666.1 - 0.00013 22.0 0.0 0.00018 21.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EWM29666.1 - 0.00018 21.1 0.0 0.0024 17.5 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EWM29666.1 - 0.0012 18.3 0.0 0.0014 18.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 EWM29666.1 - 0.0017 18.8 0.1 0.0029 18.0 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 EWM29666.1 - 0.012 15.0 0.0 0.045 13.2 0.0 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 EWM29666.1 - 0.019 14.7 0.1 0.028 14.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EWM29666.1 - 0.023 14.5 0.0 0.068 12.9 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EWM29666.1 - 0.027 14.7 0.0 0.055 13.7 0.0 1.7 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 EWM29666.1 - 0.04 14.4 0.1 0.07 13.6 0.1 1.5 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 EWM29666.1 - 0.071 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Septin PF00735.18 EWM29666.1 - 0.097 11.9 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Septin Hpr_kinase_C PF07475.12 EWM29666.1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_5 PF07728.14 EWM29666.1 - 0.16 11.9 0.1 1.3 9.0 0.0 2.3 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) DUF3641 PF12345.8 EWM29668.1 - 9.4e-53 177.9 0.0 1.6e-52 177.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3641) Radical_SAM PF04055.21 EWM29668.1 - 4.8e-10 40.1 0.0 2.5e-09 37.7 0.0 2.1 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 EWM29668.1 - 1.4e-05 25.3 0.0 2.9e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain GpcrRhopsn4 PF10192.9 EWM29669.1 - 2.9e-38 131.7 0.2 4.1e-38 131.3 0.2 1.1 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain EptA_B_N PF08019.12 EWM29669.1 - 0.083 12.8 9.0 1.8 8.4 0.3 3.3 1 1 2 3 3 3 0 Phosphoethanolamine transferase EptA/EptB DUF485 PF04341.12 EWM29669.1 - 0.32 11.0 3.2 4.8 7.2 1.9 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF485 TMEM189_B_dmain PF10520.9 EWM29670.1 - 3.4e-14 53.3 0.8 5.1e-14 52.8 0.3 1.6 2 0 0 2 2 2 1 B domain of TMEM189, localisation domain PGA_cap PF09587.10 EWM29671.1 - 0.017 14.6 0.0 0.021 14.3 0.0 1.1 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap Peptidase_S28 PF05577.12 EWM29672.1 - 3.5e-66 223.8 0.0 8.3e-66 222.6 0.0 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Amino_oxidase PF01593.24 EWM29673.1 - 1.2e-08 34.7 2.5 2.2e-05 24.0 0.0 2.5 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EWM29673.1 - 4.8e-05 23.5 3.7 5.5e-05 23.3 0.5 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EWM29673.1 - 0.001 18.3 7.8 0.083 12.0 0.0 2.5 3 0 0 3 3 3 2 FAD binding domain GMC_oxred_N PF00732.19 EWM29673.1 - 0.0026 17.2 0.0 0.0045 16.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase HI0933_like PF03486.14 EWM29673.1 - 0.031 13.0 0.2 0.61 8.7 0.2 2.1 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.14 EWM29673.1 - 0.08 12.2 0.4 0.45 9.7 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase EccE PF11203.8 EWM29673.1 - 0.48 10.8 5.4 0.13 12.6 1.7 2.0 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE FAD_oxidored PF12831.7 EWM29673.1 - 3.6 6.8 8.4 0.13 11.6 0.6 2.4 4 0 0 4 4 4 0 FAD dependent oxidoreductase Arm PF00514.23 EWM29674.1 - 2.5e-23 81.3 28.1 0.0007 19.6 0.0 12.9 14 0 0 14 14 14 6 Armadillo/beta-catenin-like repeat U-box PF04564.15 EWM29674.1 - 4.1e-13 49.3 0.0 1.4e-12 47.6 0.0 1.9 2 0 0 2 2 2 1 U-box domain Atx10homo_assoc PF09759.9 EWM29674.1 - 2.1e-09 37.3 12.3 0.3 11.1 0.1 7.9 6 2 3 9 9 9 3 Spinocerebellar ataxia type 10 protein domain Cytochrome-c551 PF10643.9 EWM29674.1 - 1.5e-05 24.7 1.3 1.7 8.2 0.0 6.4 4 2 1 6 6 6 1 Photosystem P840 reaction-centre cytochrome c-551 zf-Nse PF11789.8 EWM29674.1 - 2.9e-05 23.8 0.0 7.1e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Arm_2 PF04826.13 EWM29674.1 - 0.043 13.3 0.1 0.23 10.9 0.1 2.2 2 0 0 2 2 2 0 Armadillo-like RPAP1_N PF08621.10 EWM29674.1 - 5.4 6.9 5.4 17 5.2 0.0 3.8 4 0 0 4 4 4 0 RPAP1-like, N-terminal DNA_binding_1 PF01035.20 EWM29674.1 - 7.5 6.8 5.7 53 4.0 0.0 4.5 3 2 0 3 3 3 0 6-O-methylguanine DNA methyltransferase, DNA binding domain Zn_ribbon_17 PF17120.5 EWM29675.1 - 8.8e-11 41.3 13.1 8.8e-11 41.3 13.1 1.9 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zinc_ribbon_16 PF17034.5 EWM29675.1 - 0.0051 17.0 7.9 0.0051 17.0 7.9 2.3 1 1 1 2 2 2 1 Zinc-ribbon like family SNF2_N PF00176.23 EWM29676.1 - 6.3e-29 100.8 0.0 9.5e-29 100.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EWM29676.1 - 1.5e-06 28.5 0.0 2.8e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EWM29676.1 - 0.00021 21.4 0.0 0.0011 18.9 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit TRAUB PF08164.12 EWM29678.1 - 3.6e-16 59.5 0.2 1.7e-15 57.3 0.0 2.2 2 1 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 EWM29678.1 - 1.7e-13 51.5 1.2 8.3e-13 49.2 0.0 2.0 2 0 0 2 2 2 1 Apoptosis antagonizing transcription factor Cwf_Cwc_15 PF04889.12 EWM29678.1 - 0.0069 16.2 11.0 0.011 15.5 11.0 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.13 EWM29678.1 - 0.047 13.6 7.7 0.078 12.8 7.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region SspO PF08175.12 EWM29678.1 - 0.11 13.0 2.4 0.12 12.9 0.0 2.4 2 0 0 2 2 2 0 Small acid-soluble spore protein O family CDC45 PF02724.14 EWM29678.1 - 0.14 10.4 7.3 0.18 10.0 7.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EWM29678.1 - 0.17 10.1 16.1 0.23 9.6 16.1 1.1 1 0 0 1 1 1 0 Nop14-like family Roughex PF06020.11 EWM29678.1 - 0.34 10.0 7.6 0.47 9.5 7.6 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Pes-10 PF07149.11 EWM29678.1 - 8.7 5.3 11.4 12 4.8 11.4 1.1 1 0 0 1 1 1 0 Pes-10 RRN3 PF05327.11 EWM29678.1 - 9.1 4.7 8.1 13 4.2 8.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SET PF00856.28 EWM29679.1 - 1.9e-15 57.6 0.2 6.2e-14 52.7 0.0 2.1 2 0 0 2 2 2 1 SET domain DUF4703 PF15775.5 EWM29679.1 - 2.6 7.8 10.9 0.49 10.2 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4703) Nop16 PF09420.10 EWM29681.1 - 5.1e-07 29.9 0.8 0.0065 16.5 0.5 2.0 1 1 1 2 2 2 2 Ribosome biogenesis protein Nop16 LRR_6 PF13516.6 EWM29682.1 - 4.9e-39 129.1 18.6 4.8e-05 23.1 0.0 11.4 11 0 0 11 11 11 10 Leucine Rich repeat LRR_4 PF12799.7 EWM29682.1 - 1.6e-15 56.9 1.8 0.0032 17.9 0.1 6.6 4 1 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EWM29682.1 - 9.8e-09 34.9 12.5 0.11 12.3 0.2 6.6 2 2 4 6 6 6 6 Leucine rich repeat LRR_1 PF00560.33 EWM29682.1 - 1.9e-07 30.6 0.0 4.9 8.1 0.0 7.7 8 1 0 8 8 8 1 Leucine Rich Repeat CDP-OH_P_transf PF01066.21 EWM29685.1 - 1.7e-14 54.3 2.1 2.3e-14 53.9 0.2 2.0 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Gly_transf_sug PF04488.15 EWM29686.1 - 7.3e-11 42.6 0.0 1.3e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EWM29686.1 - 8.6e-05 22.0 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 EWM29686.1 - 0.0012 18.2 0.0 0.0018 17.7 0.0 1.1 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain Isochorismatase PF00857.20 EWM29687.1 - 2.8e-35 122.1 0.0 3.2e-35 121.9 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family NifU_N PF01592.16 EWM29688.1 - 2e-53 179.9 0.1 2.5e-53 179.6 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain AAA_25 PF13481.6 EWM29689.1 - 0.00014 21.6 0.0 0.041 13.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 EWM29689.1 - 0.00067 19.6 0.0 0.0013 18.6 0.0 1.4 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EWM29689.1 - 0.0011 19.4 0.1 0.0024 18.3 0.1 1.6 1 1 1 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 EWM29689.1 - 0.0038 17.6 0.0 0.044 14.2 0.0 2.1 2 0 0 2 2 2 1 RNA helicase AAA PF00004.29 EWM29689.1 - 0.0096 16.4 0.0 3.8 7.9 0.0 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Terminase_4 PF05119.12 EWM29689.1 - 0.028 14.8 0.0 0.05 14.0 0.0 1.4 1 0 0 1 1 1 0 Phage terminase, small subunit DUF4747 PF15931.5 EWM29689.1 - 0.15 11.7 0.0 0.19 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4747) PSII_BNR PF14870.6 EWM29690.1 - 6.1e-121 403.3 2.4 7.5e-121 403.0 2.4 1.0 1 0 0 1 1 1 1 Photosynthesis system II assembly factor YCF48 BNR PF02012.20 EWM29690.1 - 3e-07 29.4 8.4 1.6 9.1 0.1 6.1 6 0 0 6 6 6 4 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 EWM29690.1 - 7e-07 28.4 0.0 0.017 13.9 0.0 3.2 2 1 0 3 3 3 3 Sortilin, neurotensin receptor 3, TAT_signal PF10518.9 EWM29690.1 - 0.01 15.6 5.3 0.01 15.6 5.3 2.4 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence Peripla_BP_2 PF01497.18 EWM29690.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein UCR_Fe-S_N PF10399.9 EWM29690.1 - 3.5 7.0 9.4 3.2 7.2 0.4 2.5 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal peroxidase PF00141.23 EWM29691.1 - 9.7e-43 146.5 0.0 1.9e-42 145.5 0.0 1.5 1 1 0 1 1 1 1 Peroxidase CBM_2 PF00553.19 EWM29691.1 - 2.1 8.7 5.1 29 5.1 0.2 3.0 2 1 0 2 2 2 0 Cellulose binding domain Glyco_hydro_31 PF01055.26 EWM29692.1 - 6.8e-60 203.5 0.0 9.9e-60 202.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EWM29692.1 - 0.14 12.5 0.1 0.49 10.7 0.1 2.0 1 1 0 1 1 1 0 Galactose mutarotase-like CASP_C PF08172.12 EWM29693.1 - 0.066 12.5 0.0 0.089 12.1 0.0 1.1 1 0 0 1 1 1 0 CASP C terminal DUF1298 PF06974.13 EWM29694.1 - 1.2e-20 73.9 0.0 2e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) WES_acyltransf PF03007.16 EWM29694.1 - 6.7e-05 22.8 0.1 0.36 10.5 0.0 2.5 2 0 0 2 2 2 2 Wax ester synthase-like Acyl-CoA acyltransferase domain Condensation PF00668.20 EWM29694.1 - 0.077 11.6 0.0 4.6 5.8 0.0 2.1 2 0 0 2 2 2 0 Condensation domain Metallothio_Pro PF02069.16 EWM29694.1 - 0.23 11.7 0.0 0.43 10.8 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic metallothionein PCIF1_WW PF12237.8 EWM29696.1 - 1.3e-54 184.4 0.0 5.7e-52 175.8 0.0 2.4 2 0 0 2 2 2 2 Phosphorylated CTD interacting factor 1 WW domain Abhydrolase_3 PF07859.13 EWM29697.1 - 3.6e-60 203.4 0.1 1.7e-59 201.2 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 EWM29697.1 - 2.8e-08 33.1 0.1 9.4e-08 31.4 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 EWM29697.1 - 6.3e-08 32.4 0.0 3.5e-07 29.9 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 EWM29697.1 - 0.065 12.8 0.0 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Say1_Mug180 PF10340.9 EWM29697.1 - 0.08 11.8 0.0 0.16 10.8 0.0 1.4 1 1 0 1 1 1 0 Steryl acetyl hydrolase Glucan_synthase PF02364.15 EWM29698.1 - 8.3e-194 646.1 14.0 6.1e-170 567.2 11.0 2.8 1 1 1 2 2 2 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 EWM29698.1 - 6.4e-21 75.0 2.1 2.9e-20 72.9 2.1 2.2 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 RRM_1 PF00076.22 EWM29699.1 - 3.4e-23 81.2 0.4 3.3e-12 46.0 0.0 3.9 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EWM29699.1 - 5.8e-08 32.5 0.0 0.0075 16.1 0.0 2.7 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_7 PF16367.5 EWM29699.1 - 4.6e-07 29.9 0.0 0.0068 16.5 0.0 2.9 2 2 0 2 2 2 2 RNA recognition motif RRM_Rrp7 PF17799.1 EWM29699.1 - 0.013 15.3 0.0 7.4 6.4 0.0 2.9 1 1 1 3 3 3 0 Rrp7 RRM-like N-terminal domain Spo7_2_N PF15407.6 EWM29699.1 - 0.042 13.5 0.0 0.92 9.2 0.0 2.4 2 0 0 2 2 2 0 Sporulation protein family 7 cNMPbd_u2 PF16643.5 EWM29699.1 - 0.067 13.7 2.0 0.26 11.7 2.0 1.9 2 0 0 2 2 2 0 Unstructured region on cNMP-binding protein Sec63 PF02889.16 EWM29702.1 - 1e-123 411.5 0.0 6.5e-77 258.2 0.0 2.5 2 1 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EWM29702.1 - 4e-54 183.0 0.0 1.2e-26 93.6 0.0 2.9 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 EWM29702.1 - 5.2e-21 75.4 0.0 6.6e-11 42.5 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EWM29702.1 - 2.5e-16 60.0 0.2 3.2e-07 30.7 0.0 3.8 3 1 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 EWM29702.1 - 1.9e-07 31.4 0.2 0.013 15.8 0.1 2.9 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 EWM29702.1 - 0.00052 19.2 0.0 1.2 8.1 0.0 2.7 3 0 0 3 3 3 2 Type II/IV secretion system protein PhoH PF02562.16 EWM29702.1 - 0.00073 19.0 0.1 0.99 8.8 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_16 PF13191.6 EWM29702.1 - 0.0077 16.6 0.3 6.2 7.2 0.0 3.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 EWM29702.1 - 0.01 16.2 0.4 5.7 7.3 0.1 2.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EWM29702.1 - 0.02 14.6 0.3 1.4 8.6 0.0 3.0 4 0 0 4 4 4 0 IstB-like ATP binding protein UvrD-helicase PF00580.21 EWM29702.1 - 0.032 13.8 0.1 8.5 5.8 0.0 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_11 PF13086.6 EWM29702.1 - 0.089 12.6 0.0 6.6 6.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EWM29702.1 - 0.12 12.1 0.0 7.6 6.2 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 EWM29702.1 - 0.14 11.6 0.2 27 4.2 0.0 2.7 3 0 0 3 3 3 0 P-loop containing dynein motor region MRP-S33 PF08293.11 EWM29702.1 - 4.6 7.5 5.9 2.6e+02 1.9 0.0 3.6 3 0 0 3 3 3 0 Mitochondrial ribosomal subunit S27 CBS PF00571.28 EWM29703.1 - 4.5e-19 68.6 0.5 3.1e-10 40.4 0.0 2.5 2 0 0 2 2 2 2 CBS domain DHH PF01368.20 EWM29703.1 - 4.1e-10 39.8 0.5 1.2e-09 38.3 0.3 1.8 2 0 0 2 2 2 1 DHH family DHHA1 PF02272.19 EWM29703.1 - 0.046 14.1 0.1 0.1 13.0 0.1 1.7 1 0 0 1 1 1 0 DHHA1 domain FXR_C1 PF16096.5 EWM29703.1 - 0.14 12.4 0.0 1.1 9.6 0.0 2.1 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 PP-binding PF00550.25 EWM29704.1 - 6.7e-06 26.4 0.1 1.2e-05 25.5 0.1 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep_2 PF14602.6 EWM29704.1 - 0.00013 21.7 11.0 0.28 11.0 0.3 5.8 5 1 1 6 6 6 3 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 EWM29704.1 - 0.00037 20.1 22.4 0.16 11.7 0.5 7.5 8 1 0 8 8 8 3 Bacterial transferase hexapeptide (six repeats) HEAT PF02985.22 EWM29705.1 - 3.7e-18 64.0 18.7 0.093 13.0 0.8 11.3 11 0 0 11 11 10 5 HEAT repeat HEAT_2 PF13646.6 EWM29705.1 - 1.4e-11 44.6 10.7 0.82 10.1 0.0 9.2 7 2 4 11 11 11 3 HEAT repeats IFRD PF05004.13 EWM29705.1 - 7.5e-11 41.7 6.7 0.00049 19.3 0.0 5.1 5 0 0 5 5 5 3 Interferon-related developmental regulator (IFRD) Cnd1 PF12717.7 EWM29705.1 - 2.2e-10 40.8 7.9 0.037 14.1 0.0 6.6 7 0 0 7 7 7 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EWM29705.1 - 2.7e-09 37.5 0.0 7.3e-06 26.5 0.0 4.9 4 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region Tti2 PF10521.9 EWM29705.1 - 7.8e-08 32.2 1.2 0.0011 18.5 0.0 4.3 4 1 1 5 5 5 2 Tti2 family RIX1 PF08167.12 EWM29705.1 - 3.6e-07 30.1 4.7 0.03 14.1 0.3 4.4 5 0 0 5 5 5 3 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.6 EWM29705.1 - 7.3e-07 29.6 31.6 0.22 12.1 0.1 10.5 10 2 2 12 12 11 5 HEAT-like repeat CLASP_N PF12348.8 EWM29705.1 - 1e-06 28.5 1.5 0.001 18.7 0.0 5.5 4 3 2 6 6 6 2 CLASP N terminal IBN_N PF03810.19 EWM29705.1 - 1.1e-06 28.5 0.3 6.5e-06 26.0 0.1 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF577 PF04510.12 EWM29705.1 - 1.9e-05 24.7 0.4 7.6e-05 22.7 0.3 2.0 2 0 0 2 2 2 1 Family of unknown function (DUF577) Arm PF00514.23 EWM29705.1 - 4.2e-05 23.4 10.4 0.48 10.6 0.1 7.3 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat ParcG PF10274.9 EWM29705.1 - 0.00061 19.9 0.1 1.1 9.3 0.0 4.8 4 1 1 5 5 5 1 Parkin co-regulated protein Adaptin_N PF01602.20 EWM29705.1 - 0.0014 17.3 4.0 0.24 9.9 0.0 4.9 5 2 0 5 5 5 1 Adaptin N terminal region RasGEF_N_2 PF14663.6 EWM29705.1 - 0.011 16.2 4.3 5.3 7.5 0.2 4.3 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Ipi1_N PF12333.8 EWM29705.1 - 0.042 14.4 0.3 10 6.8 0.0 3.7 3 1 1 4 4 3 0 Rix1 complex component involved in 60S ribosome maturation CAS_CSE1 PF03378.15 EWM29705.1 - 0.14 10.6 2.3 15 4.0 0.0 4.5 6 0 0 6 6 6 0 CAS/CSE protein, C-terminus MMS19_C PF12460.8 EWM29705.1 - 0.41 9.7 11.4 8 5.5 0.0 5.2 5 2 1 6 6 6 0 RNAPII transcription regulator C-terminal ACP53EA PF06313.11 EWM29705.1 - 2.2 8.5 4.9 85 3.4 0.1 4.0 4 0 0 4 4 4 0 Drosophila ACP53EA protein INSIG PF07281.12 EWM29706.1 - 0.0055 16.4 1.9 0.86 9.2 0.4 2.5 2 1 0 2 2 2 2 Insulin-induced protein (INSIG) Pribosyltran_N PF13793.6 EWM29707.1 - 2.1e-51 172.8 0.4 1e-50 170.5 0.1 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EWM29707.1 - 1.2e-25 90.7 0.9 5e-25 88.6 0.6 2.0 1 1 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EWM29707.1 - 3.3e-12 46.2 0.7 1.2e-11 44.4 0.3 2.0 2 0 0 2 2 2 1 Phosphoribosyl transferase domain TraL PF07178.11 EWM29707.1 - 0.034 14.6 0.1 0.08 13.4 0.1 1.5 1 0 0 1 1 1 0 TraL protein WD40 PF00400.32 EWM29709.1 - 6.5e-19 67.9 11.5 0.002 18.9 0.4 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM29709.1 - 7.5e-07 29.4 0.0 0.65 10.3 0.0 5.0 4 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EWM29709.1 - 0.042 13.9 0.2 2.1 8.4 0.0 3.4 4 1 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Ge1_WD40 PF16529.5 EWM29709.1 - 0.073 12.0 0.0 2.3 7.1 0.0 2.8 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EWM29709.1 - 0.095 11.3 0.0 3.6 6.1 0.0 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 MORN PF02493.20 EWM29710.1 - 6.8e-48 157.8 45.1 4.2e-07 29.5 1.3 9.7 9 0 0 9 9 9 9 MORN repeat Peptidase_S9_N PF02897.15 EWM29711.1 - 3.3e-80 269.9 0.0 5e-80 269.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 EWM29711.1 - 1.1e-56 191.7 0.0 2.4e-56 190.5 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 EWM29711.1 - 0.0052 15.5 0.0 0.0092 14.7 0.0 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 EWM29711.1 - 0.049 13.5 0.0 0.94 9.3 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold Porin_3 PF01459.22 EWM29712.1 - 8.6e-40 136.9 0.0 1.1e-39 136.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic porin UnbV_ASPIC PF07593.12 EWM29712.1 - 0.00064 19.6 0.0 0.0018 18.2 0.0 1.7 1 0 0 1 1 1 1 ASPIC and UnbV Pantoate_ligase PF02569.15 EWM29713.1 - 1.1e-57 195.3 0.0 1.2e-57 195.2 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Ras PF00071.22 EWM29714.1 - 6.8e-59 198.1 0.1 9.5e-59 197.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EWM29714.1 - 4.8e-37 126.8 0.1 8.9e-37 126.0 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EWM29714.1 - 2.1e-14 53.4 0.1 3.1e-14 52.8 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EWM29714.1 - 4.5e-05 23.1 0.1 0.00013 21.6 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EWM29714.1 - 0.00019 20.9 0.0 0.00041 19.8 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EWM29714.1 - 0.00048 19.5 0.1 0.00072 19.0 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EWM29714.1 - 0.0007 19.5 0.0 0.47 10.3 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EWM29714.1 - 0.0012 18.9 0.1 0.0025 17.9 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 EWM29714.1 - 0.0046 16.5 0.0 0.0087 15.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 EWM29714.1 - 0.16 12.3 0.0 1.3 9.3 0.0 2.3 2 1 1 3 3 3 0 AAA domain Mannosyl_trans3 PF11051.8 EWM29715.1 - 3.5e-25 88.9 0.0 2.9e-23 82.6 0.0 2.1 1 1 0 1 1 1 1 Mannosyltransferase putative PP1_inhibitor PF05361.12 EWM29716.1 - 2.9e-08 33.8 1.3 4.1e-08 33.3 1.2 1.3 1 1 0 1 1 1 1 PKC-activated protein phosphatase-1 inhibitor BCDHK_Adom3 PF10436.9 EWM29716.1 - 0.083 12.7 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase SAPS PF04499.15 EWM29717.1 - 0.00028 19.8 0.0 0.0073 15.1 0.0 2.4 2 0 0 2 2 2 2 SIT4 phosphatase-associated protein AP3D1 PF06375.11 EWM29717.1 - 0.11 12.8 2.2 0.79 10.0 0.8 2.2 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 BCDHK_Adom3 PF10436.9 EWM29718.1 - 1.6e-26 93.1 0.0 2.4e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EWM29718.1 - 8.8e-12 45.5 0.0 5.8e-11 42.9 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EWM29718.1 - 0.00036 20.4 0.0 0.00083 19.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PDZ_6 PF17820.1 EWM29719.1 - 0.02 14.8 0.2 0.12 12.2 0.1 2.1 2 0 0 2 2 2 0 PDZ domain PDZ_2 PF13180.6 EWM29719.1 - 0.15 12.4 0.2 0.29 11.5 0.2 1.4 1 0 0 1 1 1 0 PDZ domain MYEOV2 PF15004.6 EWM29722.1 - 0.0014 19.0 0.5 0.0027 18.1 0.5 1.5 1 1 0 1 1 1 1 Myeloma-overexpressed-like Amidohydro_1 PF01979.20 EWM29723.1 - 1e-65 222.3 0.0 8.6e-45 153.5 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 EWM29723.1 - 1.4e-09 37.9 0.1 0.00074 19.1 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family ketoacyl-synt PF00109.26 EWM29724.1 - 6.5e-86 288.0 0.3 1.4e-85 286.9 0.1 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.28 EWM29724.1 - 4.2e-75 252.9 0.0 6.4e-75 252.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Acyl_transf_1 PF00698.21 EWM29724.1 - 7.1e-53 180.2 0.0 1.3e-52 179.3 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EWM29724.1 - 5.1e-44 149.1 0.0 2.4e-43 146.9 0.0 2.2 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 EWM29724.1 - 2.6e-11 43.7 0.1 6.5e-11 42.4 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 EWM29724.1 - 1.7e-07 30.9 0.5 5e-07 29.3 0.2 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 EWM29724.1 - 1.1e-06 29.0 0.0 3.1e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension SAT PF16073.5 EWM29724.1 - 0.0061 16.3 1.1 0.15 11.7 1.1 2.3 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis AMP-binding_C_2 PF14535.6 EWM29724.1 - 0.051 13.9 0.1 0.16 12.3 0.1 1.9 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Arf PF00025.21 EWM29725.1 - 2.7e-74 248.4 0.0 3e-74 248.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EWM29725.1 - 7.4e-16 58.4 0.0 1e-15 58.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EWM29725.1 - 7.7e-13 48.3 0.2 1.8e-08 34.0 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EWM29725.1 - 1.2e-12 47.7 0.0 1.4e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EWM29725.1 - 2.4e-12 46.7 0.0 2.9e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EWM29725.1 - 2e-09 37.5 0.0 3e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EWM29725.1 - 4.5e-08 32.7 0.0 5.5e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 EWM29725.1 - 2.5e-06 27.1 0.8 1.7e-05 24.4 0.8 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EWM29725.1 - 0.028 13.9 0.1 4.6 6.7 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 EWM29725.1 - 0.031 14.8 0.0 0.051 14.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EWM29725.1 - 0.044 14.3 0.1 0.11 13.0 0.1 1.6 1 1 0 1 1 1 0 ABC transporter MeaB PF03308.16 EWM29725.1 - 0.051 12.6 0.2 1.5 7.7 0.0 2.6 2 1 1 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Bromodomain PF00439.25 EWM29726.1 - 1e-17 64.0 0.0 1.9e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Bromodomain TIG PF01833.24 EWM29726.1 - 1.3e-08 34.8 0.0 3e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 IPT/TIG domain AAA PF00004.29 EWM29726.1 - 7.4e-06 26.4 0.0 4.1e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EWM29726.1 - 4.1e-05 24.0 0.0 0.00012 22.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 EWM29726.1 - 0.00058 19.8 0.1 0.037 13.9 0.0 2.8 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_22 PF13401.6 EWM29726.1 - 0.0015 18.8 0.0 0.0047 17.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EWM29726.1 - 0.0032 17.6 0.0 0.014 15.6 0.0 2.2 1 0 0 1 1 1 1 AAA domain HTH_5 PF01022.20 EWM29726.1 - 0.022 14.6 0.6 0.092 12.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family DUF815 PF05673.13 EWM29726.1 - 0.11 11.6 0.2 0.3 10.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Glyco_transf_28 PF03033.20 EWM29727.1 - 1.6e-19 70.3 0.0 4.1e-19 69.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain ATG_C PF09333.11 EWM29727.1 - 1.9e-08 34.5 0.1 6.3e-08 32.9 0.1 1.8 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain PH PF00169.29 EWM29727.1 - 8.8e-07 29.4 0.0 0.00036 21.0 0.0 2.3 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 EWM29727.1 - 0.0024 18.3 0.1 0.015 15.7 0.1 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain UDPGT PF00201.18 EWM29727.1 - 0.0027 16.6 0.0 0.0042 15.9 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 EWM29727.1 - 0.0045 17.0 0.0 0.0083 16.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain PH_8 PF15409.6 EWM29727.1 - 0.041 14.2 0.5 0.17 12.2 0.1 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain VPS13_C PF16909.5 EWM29727.1 - 0.32 10.8 0.3 1.6 8.5 0.2 1.9 1 1 1 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal RPE65 PF03055.15 EWM29728.1 - 3e-111 372.9 0.0 3.5e-111 372.7 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein TPR_14 PF13428.6 EWM29729.1 - 0.0057 17.4 8.1 1.7 9.6 0.5 5.1 2 1 1 3 3 3 2 Tetratricopeptide repeat DUF1168 PF06658.12 EWM29730.1 - 1.7e-06 27.9 17.8 2.2e-06 27.5 17.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) NARP1 PF12569.8 EWM29730.1 - 0.79 8.6 7.7 0.87 8.4 7.7 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4746 PF15928.5 EWM29730.1 - 4.6 6.6 8.4 5.7 6.3 8.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Enolase_C PF00113.22 EWM29732.1 - 2.9e-151 502.7 0.8 2.9e-151 502.7 0.8 1.4 2 0 0 2 2 2 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EWM29732.1 - 8.1e-60 200.7 0.1 1.8e-59 199.6 0.1 1.6 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EWM29732.1 - 4.6e-07 29.6 0.0 7.6e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 EWM29732.1 - 1.4e-05 24.3 0.6 2.5e-05 23.6 0.1 1.6 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus Snf7 PF03357.21 EWM29733.1 - 1e-12 48.0 7.1 1.2e-12 47.7 7.1 1.1 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 EWM29733.1 - 6.1e-05 23.0 3.9 0.0001 22.3 3.9 1.3 1 1 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Hamartin PF04388.12 EWM29733.1 - 0.026 13.2 0.2 0.033 12.9 0.2 1.1 1 0 0 1 1 1 0 Hamartin protein DUF4172 PF13776.6 EWM29733.1 - 0.029 14.7 0.7 0.32 11.4 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4172) Cortex-I_coil PF09304.10 EWM29733.1 - 0.03 14.5 4.5 0.1 12.8 4.3 2.0 1 1 0 1 1 1 0 Cortexillin I, coiled coil Nre_N PF04894.12 EWM29733.1 - 0.063 13.1 0.2 0.077 12.8 0.2 1.2 1 0 0 1 1 1 0 Archaeal Nre, N-terminal DUF4795 PF16043.5 EWM29733.1 - 0.17 11.5 4.2 0.29 10.7 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Peptidase_C97 PF05903.14 EWM29734.1 - 7.3e-30 103.8 0.0 9.8e-30 103.4 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain Flavokinase PF01687.17 EWM29736.1 - 1.6e-30 105.7 0.0 2.1e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Riboflavin kinase Peptidase_C1 PF00112.23 EWM29737.1 - 3.4e-55 187.5 0.8 4.5e-55 187.1 0.8 1.1 1 0 0 1 1 1 1 Papain family cysteine protease E1_DerP2_DerF2 PF02221.15 EWM29737.1 - 1.8e-12 47.9 0.2 3.6e-12 46.9 0.2 1.5 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 EWM29737.1 - 0.0035 17.7 0.1 0.0067 16.8 0.1 1.5 1 0 0 1 1 1 1 ML-like domain Propeptide_C1 PF08127.13 EWM29737.1 - 0.025 14.5 0.1 0.048 13.6 0.1 1.4 1 0 0 1 1 1 0 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.15 EWM29737.1 - 0.86 8.3 1.6 13 4.4 0.2 2.1 2 0 0 2 2 2 0 Peptidase C1-like family Kelch_1 PF01344.25 EWM29738.1 - 3.3e-76 250.7 19.1 1.5e-16 59.7 0.1 7.1 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 EWM29738.1 - 9e-47 155.9 1.5 5.3e-09 36.0 0.0 6.5 2 2 4 6 6 6 6 Kelch motif Kelch_2 PF07646.15 EWM29738.1 - 2.4e-34 116.0 5.9 9.3e-08 31.8 0.0 7.0 7 0 0 7 7 7 5 Kelch motif Kelch_3 PF13415.6 EWM29738.1 - 4.1e-27 93.9 6.8 1.6e-05 25.1 0.0 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain BACK PF07707.15 EWM29738.1 - 1.2e-26 92.7 0.4 3.1e-26 91.4 0.1 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTB PF00651.31 EWM29738.1 - 2.1e-26 92.3 0.1 1.9e-25 89.3 0.0 2.1 1 1 1 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.6 EWM29738.1 - 8.1e-22 77.0 0.3 0.00048 20.1 0.0 6.4 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EWM29738.1 - 3.6e-06 26.8 10.5 1.6 8.8 0.0 6.3 6 0 0 6 6 6 2 Kelch motif Glyoxal_oxid_N PF07250.11 EWM29738.1 - 0.11 11.7 0.9 9.2 5.4 0.0 2.6 2 1 0 2 2 2 0 Glyoxal oxidase N-terminus PQQ_3 PF13570.6 EWM29738.1 - 0.12 12.9 8.8 19 5.9 0.0 5.3 4 1 1 5 5 5 0 PQQ-like domain PheRS_DBD3 PF18553.1 EWM29739.1 - 0.013 15.8 0.1 0.022 15.0 0.1 1.4 1 0 0 1 1 1 0 PheRS DNA binding domain 3 Meth_synt_2 PF01717.18 EWM29739.1 - 0.11 11.7 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Cobalamin-independent synthase, Catalytic domain tify PF06200.14 EWM29740.1 - 0.24 10.8 0.3 0.39 10.1 0.3 1.3 1 0 0 1 1 1 0 tify domain RRM_1 PF00076.22 EWM29744.1 - 9.7e-09 34.9 0.2 1.9e-08 34.0 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Thioredoxin PF00085.20 EWM29745.1 - 6.9e-61 202.7 0.0 3.4e-30 104.1 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 EWM29745.1 - 2.6e-19 69.9 0.2 5.6e-19 68.8 0.2 1.6 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 EWM29745.1 - 6e-15 55.4 0.0 1.3e-07 31.3 0.0 2.1 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EWM29745.1 - 1.3e-10 41.7 0.4 0.0012 19.3 0.0 3.4 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EWM29745.1 - 7.3e-09 35.7 0.0 0.0013 18.8 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 EWM29745.1 - 8.6e-06 26.0 0.0 0.13 12.6 0.0 3.5 2 2 2 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.21 EWM29745.1 - 8.9e-06 25.6 0.0 0.1 12.5 0.0 2.6 3 0 0 3 3 3 2 AhpC/TSA family HyaE PF07449.11 EWM29745.1 - 0.00032 20.6 0.0 1.1 9.3 0.0 2.8 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE ERp29_N PF07912.13 EWM29745.1 - 0.00037 20.7 0.0 0.082 13.1 0.0 2.8 3 0 0 3 3 3 1 ERp29, N-terminal domain Redoxin PF08534.10 EWM29745.1 - 0.0045 16.7 0.1 1.2 8.9 0.0 2.3 2 0 0 2 2 2 2 Redoxin Thioredoxin_6 PF13848.6 EWM29745.1 - 0.018 15.0 0.0 0.3 11.0 0.0 2.4 1 1 0 1 1 1 0 Thioredoxin-like domain HECW1_helix PF18436.1 EWM29745.1 - 0.098 12.8 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 PITH PF06201.13 EWM29746.1 - 3.3e-38 131.3 0.0 4e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 PITH domain IER PF05760.12 EWM29747.1 - 0.0068 16.8 0.2 0.0085 16.4 0.2 1.1 1 0 0 1 1 1 1 Immediate early response protein (IER) Tim17 PF02466.19 EWM29748.1 - 4.9e-07 30.1 2.6 4.9e-07 30.1 2.6 2.0 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF1269 PF06897.12 EWM29748.1 - 0.8 10.0 5.0 7.2 7.0 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) Gly-zipper_OmpA PF13436.6 EWM29748.1 - 2.9 7.8 20.6 6 6.7 4.7 2.4 2 0 0 2 2 2 0 Glycine-zipper domain Gly-zipper_YMGG PF13441.6 EWM29748.1 - 6.7 6.5 20.0 1 9.1 3.1 2.4 2 0 0 2 2 2 0 YMGG-like Gly-zipper Mito_carr PF00153.27 EWM29749.1 - 3.7e-34 116.5 0.0 2.1e-09 37.2 0.0 4.8 3 3 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.25 EWM29750.1 - 2.2e-58 197.7 0.0 4.2e-58 196.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM29750.1 - 6.7e-29 100.9 0.0 1.1e-28 100.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EWM29750.1 - 9.9e-05 21.8 0.0 0.00019 20.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like AAA_11 PF13086.6 EWM29750.1 - 0.0014 18.5 0.5 0.0014 18.5 0.5 1.8 2 0 0 2 2 2 1 AAA domain APH PF01636.23 EWM29750.1 - 0.0031 17.4 0.0 0.0031 17.4 0.0 3.0 3 1 0 3 3 3 1 Phosphotransferase enzyme family SpecificRecomb PF10136.9 EWM29750.1 - 1.5 7.0 4.1 2.2 6.5 4.1 1.2 1 0 0 1 1 1 0 Site-specific recombinase DUF5320 PF17253.2 EWM29750.1 - 3.7 8.7 8.0 0.6 11.2 0.2 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5320) G_path_suppress PF15991.5 EWM29751.1 - 5.6 7.0 15.3 10 6.2 15.3 1.4 1 0 0 1 1 1 0 G-protein pathway suppressor Med14 PF08638.11 EWM29753.1 - 1.5e-19 70.2 0.0 2.4e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit MED14 GTP_EFTU PF00009.27 EWM29754.1 - 7.3e-53 179.0 0.0 1.8e-51 174.4 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EWM29754.1 - 2.3e-13 50.0 0.0 6.8e-13 48.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 EWM29754.1 - 5.9e-10 39.1 0.0 1.5e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 EWM29754.1 - 6.3e-08 32.9 0.0 1.5e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 EWM29754.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 Elongation factor G, domain IV Semialdhyde_dhC PF02774.18 EWM29755.1 - 2e-45 155.1 0.0 3.7e-45 154.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 EWM29755.1 - 3e-29 101.9 0.1 9.9e-29 100.2 0.1 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 EWM29755.1 - 0.14 11.7 0.0 3.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain zf-RING_2 PF13639.6 EWM29757.1 - 4.7e-10 39.6 14.9 8.1e-10 38.9 14.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EWM29757.1 - 1e-08 34.7 7.9 1e-08 34.7 7.9 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 EWM29757.1 - 8.6e-05 22.3 12.0 0.00015 21.6 12.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EWM29757.1 - 0.00048 19.9 16.0 0.0008 19.2 16.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EWM29757.1 - 0.00058 20.1 14.7 0.0018 18.5 14.7 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EWM29757.1 - 0.00075 19.4 15.9 0.0014 18.6 15.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EWM29757.1 - 0.006 16.6 8.3 0.006 16.6 8.3 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EWM29757.1 - 0.012 15.4 17.0 0.021 14.7 17.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EWM29757.1 - 0.41 10.3 16.0 0.03 13.9 11.1 1.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 EWM29757.1 - 1.1 9.3 11.2 4.2 7.5 11.2 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Methyltransf_31 PF13847.6 EWM29758.1 - 1e-09 38.3 0.0 1.6e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM29758.1 - 1.1e-09 38.9 0.0 3.1e-09 37.4 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM29758.1 - 1.5e-06 28.7 0.0 2.8e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EWM29758.1 - 3.7e-05 24.4 0.0 0.0001 23.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EWM29758.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain HD_4 PF13328.6 EWM29759.1 - 9.6e-42 142.4 0.7 2.4e-41 141.1 0.7 1.7 1 0 0 1 1 1 1 HD domain HD PF01966.22 EWM29759.1 - 1.7e-06 28.3 0.1 4.3e-06 26.9 0.1 1.8 1 1 0 1 1 1 1 HD domain TGS PF02824.21 EWM29759.1 - 0.00034 20.6 0.0 0.0087 16.1 0.0 2.7 3 0 0 3 3 3 1 TGS domain Dscam_C PF12355.8 EWM29759.1 - 0.0043 18.0 0.8 0.026 15.5 0.2 2.3 2 0 0 2 2 2 1 Down syndrome cell adhesion molecule C terminal Chloroa_b-bind PF00504.21 EWM29759.1 - 0.0082 16.7 0.4 0.23 12.0 0.1 2.7 2 0 0 2 2 2 1 Chlorophyll A-B binding protein RelA_SpoT PF04607.17 EWM29759.1 - 0.23 11.8 0.0 0.44 10.9 0.0 1.4 1 0 0 1 1 1 0 Region found in RelA / SpoT proteins SMC_N PF02463.19 EWM29760.1 - 1.3e-24 86.9 0.0 3e-24 85.7 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EWM29760.1 - 3.4e-18 66.9 0.0 3.4e-18 66.9 0.0 4.2 3 1 0 4 4 4 2 AAA domain AAA_21 PF13304.6 EWM29760.1 - 2e-06 27.9 0.5 0.0001 22.2 0.0 2.6 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EWM29760.1 - 7.1e-06 26.0 1.9 4.7e-05 23.3 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 EWM29760.1 - 9.5e-05 22.1 0.0 0.00022 20.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 EWM29760.1 - 0.00073 20.1 1.6 0.0068 16.9 0.0 3.3 3 0 0 3 3 3 1 ABC transporter FliD_C PF07195.12 EWM29760.1 - 0.0087 15.5 1.1 0.27 10.6 0.0 3.3 3 0 0 3 3 3 1 Flagellar hook-associated protein 2 C-terminus AAA_27 PF13514.6 EWM29760.1 - 0.042 13.4 0.0 0.042 13.4 0.0 4.2 4 1 2 6 6 6 0 AAA domain NACHT PF05729.12 EWM29760.1 - 0.059 13.3 0.1 0.17 11.8 0.1 1.9 1 0 0 1 1 1 0 NACHT domain AAA_13 PF13166.6 EWM29760.1 - 1.3 7.6 0.0 1.3 7.6 0.0 4.6 4 2 0 4 4 3 0 AAA domain Cauli_AT PF03233.13 EWM29760.1 - 5.6 6.9 8.0 18 5.2 5.4 3.0 2 1 0 2 2 2 0 Aphid transmission protein LON_substr_bdg PF02190.16 EWM29762.1 - 3.3e-06 27.1 0.0 5e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain RNase_PH PF01138.21 EWM29763.1 - 1.5e-23 83.7 0.0 2.3e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EWM29763.1 - 0.01 15.9 0.3 0.68 10.0 0.0 2.5 1 1 1 2 2 2 0 3' exoribonuclease family, domain 2 DUF5125 PF17163.4 EWM29763.1 - 0.16 12.2 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5125) Brix PF04427.18 EWM29765.1 - 7.8e-27 94.6 0.0 1.3e-26 94.0 0.0 1.2 1 0 0 1 1 1 1 Brix domain Aminotran_4 PF01063.19 EWM29766.1 - 4.8e-20 72.4 0.0 1.1e-19 71.2 0.0 1.6 1 1 0 1 1 1 1 Amino-transferase class IV PI3_PI4_kinase PF00454.27 EWM29767.1 - 3.5e-32 112.2 0.0 8.5e-30 104.4 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Myb_DNA-binding PF00249.31 EWM29768.1 - 5.4e-12 45.7 0.1 1e-07 32.1 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EWM29768.1 - 8.6e-05 22.7 3.0 0.0021 18.3 0.1 2.8 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EWM29768.1 - 0.0053 16.6 3.3 0.1 12.5 0.4 2.6 2 0 0 2 2 2 2 Myb DNA-binding like S1FA PF04689.13 EWM29769.1 - 0.061 13.5 0.9 0.098 12.8 0.9 1.3 1 0 0 1 1 1 0 DNA binding protein S1FA FixQ PF05545.11 EWM29769.1 - 0.078 13.0 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Ac76 PF05814.11 EWM29769.1 - 0.16 12.0 0.1 0.27 11.3 0.1 1.3 1 0 0 1 1 1 0 Orf76 (Ac76) Sec7 PF01369.20 EWM29770.1 - 2.3e-62 209.9 0.3 3.6e-62 209.3 0.3 1.3 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 EWM29770.1 - 4.3e-15 56.1 1.7 2.4e-10 40.9 0.0 3.7 2 2 0 2 2 2 2 PH domain PH_11 PF15413.6 EWM29770.1 - 3.7e-07 30.5 0.1 0.00028 21.3 0.0 2.8 2 0 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 EWM29770.1 - 0.062 13.6 0.6 31 5.0 0.0 4.0 5 0 0 5 5 5 0 Pleckstrin homology domain PH_4 PF15404.6 EWM29770.1 - 0.077 12.8 0.2 0.52 10.1 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain PH_6 PF15406.6 EWM29770.1 - 0.088 13.1 0.1 3.1 8.1 0.3 2.4 1 1 1 2 2 2 0 Pleckstrin homology domain Helicase_C_2 PF13307.6 EWM29771.1 - 2e-50 171.3 0.0 4.7e-50 170.1 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 EWM29771.1 - 4.9e-46 156.5 1.8 4.9e-46 156.5 1.8 2.3 2 1 1 3 3 3 1 DEAD_2 ResIII PF04851.15 EWM29771.1 - 0.00087 19.3 0.1 1 9.3 0.0 3.3 3 1 0 3 3 3 2 Type III restriction enzyme, res subunit AAA_11 PF13086.6 EWM29771.1 - 0.002 18.0 7.1 0.0096 15.7 1.0 3.0 2 1 0 2 2 2 1 AAA domain Nop25 PF09805.9 EWM29771.1 - 5.4 7.5 12.0 0.28 11.7 6.2 1.8 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Ank_4 PF13637.6 EWM29772.1 - 4.2e-25 87.8 0.3 4.9e-11 42.9 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EWM29772.1 - 6e-23 81.2 0.0 9.2e-15 55.0 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EWM29772.1 - 4.7e-21 74.6 0.2 4.5e-10 39.6 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EWM29772.1 - 2.3e-20 72.1 0.0 7.8e-05 23.0 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 EWM29772.1 - 6e-16 56.9 0.0 4.2e-05 23.6 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Iso_dh PF00180.20 EWM29773.1 - 1.5e-78 264.4 0.0 1.8e-78 264.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase CPBP PF02517.16 EWM29775.1 - 1.8e-14 53.9 5.9 1.8e-14 53.9 5.9 2.6 2 1 1 3 3 3 1 CPBP intramembrane metalloprotease Pro_isomerase PF00160.21 EWM29777.1 - 1.2e-08 35.3 0.0 3.1e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.25 EWM29778.1 - 3.8e-68 229.7 0.0 6.6e-68 228.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM29778.1 - 1.6e-33 116.1 0.0 2.1e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EWM29778.1 - 3.7e-05 23.2 0.0 7.2e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EWM29778.1 - 0.0011 18.4 0.1 0.0022 17.4 0.1 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EWM29778.1 - 0.0027 17.7 0.0 0.0042 17.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EWM29778.1 - 0.004 16.1 0.0 0.0055 15.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 EWM29778.1 - 0.028 13.5 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 EWM29778.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 EWM29778.1 - 0.19 11.3 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ras PF00071.22 EWM29779.1 - 1.6e-50 170.8 0.0 2.2e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EWM29779.1 - 6.1e-32 110.4 0.0 9.5e-32 109.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EWM29779.1 - 2.7e-12 46.5 0.0 3.9e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EWM29779.1 - 0.00067 19.7 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EWM29779.1 - 0.0047 16.8 0.1 0.15 11.9 0.1 2.4 1 1 1 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 EWM29779.1 - 0.0085 15.5 0.0 0.013 14.8 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EWM29779.1 - 0.012 15.0 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 EWM29779.1 - 0.015 15.0 0.0 0.039 13.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EWM29779.1 - 0.026 14.3 0.0 0.53 10.0 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 EWM29779.1 - 0.027 14.5 0.0 0.071 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MCM PF00493.23 EWM29779.1 - 0.028 13.5 0.0 0.047 12.8 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_16 PF13191.6 EWM29779.1 - 0.036 14.5 0.1 0.11 12.9 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain Maf_N PF08383.11 EWM29779.1 - 0.047 13.5 0.0 0.088 12.6 0.0 1.4 1 0 0 1 1 1 0 Maf N-terminal region Neuro_bHLH PF12533.8 EWM29779.1 - 0.061 14.5 0.0 0.14 13.4 0.0 1.6 1 0 0 1 1 1 0 Neuronal helix-loop-helix transcription factor FeoB_N PF02421.18 EWM29779.1 - 0.11 12.0 0.0 4.1 6.9 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B Carbam_trans_C PF16861.5 EWM29780.1 - 1.5e-63 213.4 0.0 2.6e-63 212.6 0.0 1.4 1 0 0 1 1 1 1 Carbamoyltransferase C-terminus Carbam_trans_N PF02543.15 EWM29780.1 - 8.4e-32 111.2 0.7 3.5e-29 102.5 0.7 3.0 1 1 0 1 1 1 1 Carbamoyltransferase N-terminus Peptidase_M22 PF00814.25 EWM29780.1 - 0.00041 20.2 0.0 0.0029 17.3 0.0 2.0 2 0 0 2 2 2 1 Glycoprotease family zf-RING_5 PF14634.6 EWM29781.1 - 0.00026 20.9 18.9 0.00061 19.7 18.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EWM29781.1 - 0.0029 17.4 14.2 0.0048 16.7 14.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SlyX PF04102.12 EWM29781.1 - 0.0068 17.0 0.7 0.0068 17.0 0.7 2.5 2 1 1 3 3 3 1 SlyX zf-RING_2 PF13639.6 EWM29781.1 - 0.0085 16.4 16.9 0.018 15.3 16.9 1.6 1 0 0 1 1 1 1 Ring finger domain Phlebovirus_NSM PF07246.11 EWM29781.1 - 0.038 13.4 0.8 0.059 12.7 0.8 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF1664 PF07889.12 EWM29781.1 - 0.06 13.4 0.6 0.12 12.4 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) LMBR1 PF04791.16 EWM29781.1 - 0.18 10.7 3.0 0.21 10.5 3.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Prok-RING_4 PF14447.6 EWM29781.1 - 0.19 11.6 13.8 0.38 10.6 13.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.14 EWM29781.1 - 0.7 9.8 4.8 0.29 11.0 0.9 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif HR1 PF02185.16 EWM29781.1 - 1.3 9.2 11.2 0.048 13.8 3.5 2.6 2 1 1 3 3 3 0 Hr1 repeat zf-C3HC4_2 PF13923.6 EWM29781.1 - 1.9 8.4 21.2 0.52 10.2 18.0 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) BRE1 PF08647.11 EWM29781.1 - 6.3 6.9 13.3 0.89 9.7 4.9 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF2203 PF09969.9 EWM29781.1 - 9.3 7.0 9.3 0.17 12.6 1.3 2.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) GATase_6 PF13522.6 EWM29782.1 - 4e-15 56.2 0.0 1.5e-14 54.4 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EWM29782.1 - 2.5e-13 50.0 0.0 1.8e-12 47.3 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 EWM29782.1 - 3.6e-07 29.8 0.0 7.5e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain TPR_1 PF00515.28 EWM29783.1 - 2.7e-21 74.4 9.5 2e-06 27.3 0.3 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 EWM29783.1 - 2.1e-19 68.0 9.9 7e-06 25.8 0.5 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 EWM29783.1 - 8.2e-09 35.0 10.4 0.0096 16.1 0.0 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 EWM29783.1 - 9.9e-09 35.4 6.2 0.00012 22.3 0.5 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EWM29783.1 - 3.7e-08 32.9 13.2 3.8e-06 26.5 1.4 5.0 3 2 2 5 5 5 2 TPR repeat TPR_16 PF13432.6 EWM29783.1 - 8.5e-08 32.7 15.1 0.00037 21.1 3.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 EWM29783.1 - 3.2e-07 30.4 0.6 0.031 14.4 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EWM29783.1 - 1.5e-06 27.8 8.8 0.85 9.8 0.1 6.1 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 EWM29783.1 - 1.7e-05 24.9 5.7 0.29 11.6 0.2 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EWM29783.1 - 2.4e-05 24.3 1.1 0.03 14.4 0.1 4.4 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 EWM29783.1 - 4.7e-05 23.8 8.9 0.38 11.3 0.1 4.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EWM29783.1 - 0.0012 19.4 11.0 0.21 12.5 0.1 5.7 4 2 3 7 7 7 1 Tetratricopeptide repeat MIT PF04212.18 EWM29783.1 - 0.0026 17.8 6.0 0.36 10.9 0.3 4.3 4 1 0 4 4 4 1 MIT (microtubule interacting and transport) domain Peptidase_M32 PF02074.15 EWM29783.1 - 0.015 14.1 1.9 0.41 9.4 0.1 2.1 1 1 1 2 2 2 0 Carboxypeptidase Taq (M32) metallopeptidase DUF3856 PF12968.7 EWM29783.1 - 0.091 12.8 4.8 15 5.6 0.1 4.5 3 1 1 4 4 4 0 Domain of Unknown Function (DUF3856) MerR-DNA-bind PF09278.11 EWM29783.1 - 0.11 13.0 0.0 0.42 11.2 0.0 2.0 1 0 0 1 1 1 0 MerR, DNA binding Rapsyn_N PF10579.9 EWM29783.1 - 0.12 12.5 0.1 1.1 9.4 0.0 2.7 4 0 0 4 4 4 0 Rapsyn N-terminal myristoylation and linker region TPR_6 PF13174.6 EWM29783.1 - 0.28 11.9 14.6 0.78 10.5 0.4 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat DisA-linker PF10635.9 EWM29783.1 - 0.34 10.7 3.2 18 5.1 0.0 3.3 3 1 0 3 3 3 0 DisA bacterial checkpoint controller linker region TPR_20 PF14561.6 EWM29783.1 - 0.51 10.7 7.6 35 4.8 0.0 4.2 3 1 2 5 5 5 0 Tetratricopeptide repeat DUF5113 PF17140.4 EWM29783.1 - 2.7 7.8 5.6 39 4.0 1.5 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF5113) TPR_10 PF13374.6 EWM29783.1 - 5.5 7.0 9.9 7.4 6.6 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat tRNA_bind PF01588.20 EWM29784.1 - 8.3e-28 96.4 0.1 3.1e-26 91.3 0.0 2.3 2 0 0 2 2 2 1 Putative tRNA binding domain GST_C_2 PF13410.6 EWM29784.1 - 0.014 15.4 0.0 0.04 13.9 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EWM29784.1 - 0.027 14.7 0.0 0.059 13.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EWM29784.1 - 0.027 14.7 0.0 0.12 12.6 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain ADH_N PF08240.12 EWM29785.1 - 1.4e-28 98.9 2.9 1.4e-28 98.9 2.9 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EWM29785.1 - 1.3e-22 80.2 1.3 2e-22 79.6 0.1 1.9 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EWM29785.1 - 4.7e-05 24.5 0.0 8.9e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EWM29785.1 - 0.00017 21.0 0.0 0.00027 20.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EWM29785.1 - 0.00043 19.7 0.1 0.00099 18.5 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 EWM29785.1 - 0.0079 16.4 0.1 0.013 15.7 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 EWM29785.1 - 0.079 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CoA_binding PF02629.19 EWM29785.1 - 0.092 13.4 0.0 2.7 8.7 0.0 2.4 2 0 0 2 2 2 0 CoA binding domain ADH_N PF08240.12 EWM29786.1 - 1.4e-28 98.9 2.9 1.4e-28 98.9 2.9 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EWM29786.1 - 1.3e-22 80.2 1.3 2e-22 79.6 0.1 1.9 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EWM29786.1 - 4.7e-05 24.5 0.0 8.9e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EWM29786.1 - 0.00017 21.0 0.0 0.00027 20.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EWM29786.1 - 0.00043 19.7 0.1 0.00099 18.5 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 EWM29786.1 - 0.0079 16.4 0.1 0.013 15.7 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 EWM29786.1 - 0.079 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CoA_binding PF02629.19 EWM29786.1 - 0.092 13.4 0.0 2.7 8.7 0.0 2.4 2 0 0 2 2 2 0 CoA binding domain PNP_UDP_1 PF01048.20 EWM29787.1 - 7.4e-29 100.6 0.1 9.5e-29 100.3 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Ribosomal_L5_C PF00673.21 EWM29788.1 - 8.3e-22 77.2 0.0 1.3e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EWM29788.1 - 2.1e-19 69.6 0.0 4.7e-19 68.5 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L5 HTH_ABP1_N PF18107.1 EWM29788.1 - 0.054 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain Pyr_redox_2 PF07992.14 EWM29789.1 - 9.8e-27 93.9 0.7 1.9e-14 53.6 0.4 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EWM29789.1 - 0.00029 20.2 0.1 0.026 13.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EWM29789.1 - 0.00054 20.0 0.7 0.17 11.9 0.1 3.3 2 1 0 3 3 3 1 FAD-NAD(P)-binding GIDA PF01134.22 EWM29789.1 - 0.0026 16.9 1.3 1.5 7.8 0.0 2.6 2 1 1 3 3 3 2 Glucose inhibited division protein A DAO PF01266.24 EWM29789.1 - 0.0074 15.9 0.7 0.018 14.6 0.7 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EWM29789.1 - 0.0089 15.1 0.1 0.91 8.5 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 EWM29789.1 - 0.0095 16.5 6.7 0.059 13.9 0.3 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EWM29789.1 - 0.013 14.4 0.3 0.028 13.3 0.3 1.5 1 0 0 1 1 1 0 Tryptophan halogenase Rubredoxin_C PF18267.1 EWM29789.1 - 0.05 13.5 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 Rubredoxin NAD+ reductase C-terminal domain NAD_binding_8 PF13450.6 EWM29789.1 - 0.054 13.7 0.1 0.15 12.3 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain PIP5K PF01504.18 EWM29790.1 - 4.3e-71 239.3 0.0 6.6e-71 238.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase EF-hand_6 PF13405.6 EWM29790.1 - 7.5e-11 41.1 0.9 0.003 17.3 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 EWM29790.1 - 2.2e-09 37.6 0.2 0.0049 17.3 0.1 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EWM29790.1 - 3.6e-09 35.5 1.7 0.0014 18.1 0.1 3.6 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 EWM29790.1 - 1.2e-07 30.9 1.9 0.0029 17.0 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EWM29790.1 - 2.6e-06 27.2 0.8 0.00014 21.7 0.0 2.6 1 1 1 2 2 2 1 EF-hand domain pair Chloroa_b-bind PF00504.21 EWM29791.1 - 3.5e-40 138.2 0.1 4.6e-40 137.8 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Glyco_hydro_31 PF01055.26 EWM29793.1 - 1.2e-143 479.5 3.0 1.5e-143 479.2 3.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EWM29793.1 - 2.8e-21 75.6 0.0 7.8e-21 74.2 0.0 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like NtCtMGAM_N PF16863.5 EWM29793.1 - 0.033 14.4 0.0 0.082 13.1 0.0 1.6 1 0 0 1 1 1 0 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase PH PF00169.29 EWM29794.1 - 1.8e-11 44.5 0.8 1.4e-05 25.5 0.0 3.4 3 1 0 3 3 3 2 PH domain PH_11 PF15413.6 EWM29794.1 - 0.0034 17.8 3.2 3.2 8.2 0.1 4.0 3 1 0 3 3 3 2 Pleckstrin homology domain WD40 PF00400.32 EWM29795.1 - 8.8e-19 67.5 0.5 0.00041 21.1 0.0 5.1 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF840 PF05801.11 EWM29795.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Lagovirus protein of unknown function (DUF840) GTP_EFTU PF00009.27 EWM29796.1 - 2.9e-53 180.3 0.1 5e-53 179.5 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EWM29796.1 - 2.6e-20 72.3 0.0 5.4e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EWM29796.1 - 4.8e-08 33.3 0.9 1.3e-07 31.9 0.2 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EWM29796.1 - 1.3e-07 31.7 0.3 2.6e-07 30.7 0.3 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 EWM29796.1 - 5e-05 22.7 0.1 0.0001 21.7 0.1 1.4 1 0 0 1 1 1 1 Septin FeoB_N PF02421.18 EWM29796.1 - 0.00041 19.9 0.1 0.0074 15.8 0.1 2.9 2 1 0 2 2 2 1 Ferrous iron transport protein B EFG_II PF14492.6 EWM29796.1 - 0.0011 19.0 0.1 0.0028 17.7 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.10 EWM29796.1 - 0.023 14.1 0.1 0.13 11.6 0.0 2.2 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit Arf PF00025.21 EWM29796.1 - 0.026 14.0 0.0 0.063 12.7 0.0 1.6 2 0 0 2 2 2 0 ADP-ribosylation factor family Dynamin_N PF00350.23 EWM29796.1 - 0.062 13.4 0.0 0.43 10.6 0.0 2.0 1 1 0 1 1 1 0 Dynamin family Roc PF08477.13 EWM29796.1 - 0.14 12.4 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase N6-adenineMlase PF10237.9 EWM29797.1 - 2.6e-37 128.1 0.0 3e-37 127.9 0.0 1.0 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase PLA2_B PF01735.18 EWM29798.1 - 4.1e-22 78.3 5.2 9.4e-11 40.8 0.0 3.5 3 1 0 3 3 3 3 Lysophospholipase catalytic domain SCP2 PF02036.17 EWM29799.1 - 5.2e-47 158.5 3.5 3.4e-23 82.0 0.1 2.2 2 0 0 2 2 2 2 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 EWM29799.1 - 1.4e-12 48.0 0.9 7.9e-06 26.2 0.1 2.2 2 0 0 2 2 2 2 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 EWM29799.1 - 1.7e-05 25.1 0.1 0.005 17.2 0.0 2.3 2 0 0 2 2 2 2 Sterol carrier protein domain SCP_3 PF17844.1 EWM29799.1 - 0.01 15.6 0.0 2.8 7.8 0.0 2.6 2 1 0 2 2 2 0 Bacterial SCP ortholog MTS PF05175.14 EWM29799.1 - 0.059 12.9 0.7 0.33 10.5 0.1 2.1 2 1 0 2 2 2 0 Methyltransferase small domain DUF1754 PF08555.10 EWM29799.1 - 0.29 11.9 3.6 1.5 9.6 1.3 2.3 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) EFP_N PF08207.12 EWM29800.1 - 3.5e-18 65.4 0.2 7.2e-18 64.4 0.2 1.6 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Elong-fact-P_C PF09285.11 EWM29800.1 - 1.6e-16 59.8 0.1 3.1e-16 58.9 0.1 1.5 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP PF01132.20 EWM29800.1 - 4.9e-15 55.3 0.2 1e-14 54.3 0.2 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain Hist_deacetyl PF00850.19 EWM29801.1 - 2e-81 273.8 0.2 2.5e-81 273.5 0.2 1.1 1 0 0 1 1 1 1 Histone deacetylase domain RRM_1 PF00076.22 EWM29802.1 - 8.6e-24 83.2 0.1 4.3e-11 42.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EWM29802.1 - 0.00071 19.2 0.0 0.083 12.5 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EWM29802.1 - 0.0021 17.9 0.0 1.3 8.9 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif SMN PF06003.12 EWM29802.1 - 1.1 8.5 3.1 1.5 8.0 3.1 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) GAS PF13851.6 EWM29803.1 - 0.0032 16.8 21.5 0.0032 16.8 21.5 6.4 4 1 3 7 7 7 2 Growth-arrest specific micro-tubule binding Vps23_core PF09454.10 EWM29803.1 - 0.16 12.0 1.6 7.3 6.6 0.1 3.5 3 0 0 3 3 3 0 Vps23 core domain Guanylate_kin PF00625.21 EWM29804.1 - 4.8e-54 182.8 0.0 6.3e-54 182.4 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 EWM29804.1 - 1.6e-05 25.1 0.0 4.2e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EWM29804.1 - 0.00065 19.6 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 EWM29804.1 - 0.005 17.4 0.0 0.011 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EWM29804.1 - 0.0067 16.7 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EWM29804.1 - 0.0071 16.7 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 EWM29804.1 - 0.0096 15.8 0.1 0.021 14.8 0.0 1.6 2 0 0 2 2 2 1 NTPase MMR_HSR1 PF01926.23 EWM29804.1 - 0.026 14.6 0.0 0.048 13.7 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 EWM29804.1 - 0.053 14.0 0.0 0.085 13.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 EWM29804.1 - 0.065 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 EWM29804.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_14 PF13173.6 EWM29804.1 - 0.13 12.3 0.2 0.47 10.5 0.0 2.2 2 1 0 2 2 2 0 AAA domain Proteasome_A_N PF10584.9 EWM29805.1 - 2.7e-08 33.3 0.2 4.1e-08 32.8 0.2 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Acyl-CoA_dh_1 PF00441.24 EWM29806.1 - 9.6e-35 120.0 5.9 1.4e-34 119.5 5.9 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EWM29806.1 - 3.5e-18 65.6 0.0 7e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EWM29806.1 - 9.1e-11 42.2 8.4 1.3e-10 41.6 7.9 1.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EWM29806.1 - 9.8e-11 42.3 0.0 3.3e-10 40.6 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain GUN4 PF05419.12 EWM29807.1 - 2.3e-44 150.9 0.0 2.9e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 GUN4-like Peptidase_M16_C PF05193.21 EWM29808.1 - 1.7e-09 37.9 0.0 4.3e-09 36.6 0.0 1.7 1 1 0 1 1 1 1 Peptidase M16 inactive domain NAC PF01849.18 EWM29809.1 - 1.4e-22 79.4 0.3 2.5e-22 78.6 0.3 1.5 1 0 0 1 1 1 1 NAC domain Sugar_tr PF00083.24 EWM29810.1 - 8.1e-103 344.7 25.4 2.7e-79 267.1 13.4 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EWM29810.1 - 1.9e-26 92.8 42.9 7.9e-21 74.4 19.1 3.3 2 1 1 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.13 EWM29810.1 - 5.1e-08 31.8 3.7 5.1e-08 31.8 3.7 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MbtH PF03621.13 EWM29810.1 - 0.14 11.6 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 MbtH-like protein PSI PF01437.25 EWM29810.1 - 0.28 11.8 3.4 0.73 10.4 3.4 1.7 1 0 0 1 1 1 0 Plexin repeat Abhydrolase_2 PF02230.16 EWM29812.1 - 7.1e-31 107.7 0.0 1.1e-30 107.0 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EWM29812.1 - 4.4e-06 26.3 0.1 0.011 15.2 0.1 2.7 2 1 1 3 3 3 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EWM29812.1 - 4.8e-06 26.0 0.3 0.003 16.9 0.0 3.2 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EWM29812.1 - 0.00012 22.0 0.1 0.00047 20.1 0.0 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EWM29812.1 - 0.00014 22.6 1.8 0.00019 22.1 1.5 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 EWM29812.1 - 0.0013 18.8 0.0 0.0041 17.2 0.0 1.8 1 0 0 1 1 1 1 TAP-like protein DLH PF01738.18 EWM29812.1 - 0.002 17.7 0.0 0.0041 16.7 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Esterase_phd PF10503.9 EWM29812.1 - 0.0021 17.6 0.0 0.0075 15.8 0.0 1.9 1 1 1 2 2 2 1 Esterase PHB depolymerase Abhydrolase_1 PF00561.20 EWM29812.1 - 0.0062 16.2 0.3 0.021 14.5 0.2 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 EWM29812.1 - 0.012 15.4 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family AXE1 PF05448.12 EWM29812.1 - 0.18 10.4 0.0 0.27 9.9 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) TAL_FSA PF00923.19 EWM29813.1 - 3.9e-196 650.0 0.0 6.8e-98 327.5 0.0 2.0 2 0 0 2 2 2 2 Transaldolase/Fructose-6-phosphate aldolase ALAD PF00490.21 EWM29813.1 - 0.044 12.9 0.1 8.5 5.4 0.0 2.2 2 0 0 2 2 2 0 Delta-aminolevulinic acid dehydratase MerR_2 PF13591.6 EWM29813.1 - 0.072 12.9 0.0 24 4.9 0.0 2.8 2 0 0 2 2 2 0 MerR HTH family regulatory protein RACo_linker PF17650.1 EWM29813.1 - 0.13 12.2 0.3 31 4.5 0.0 2.9 3 0 0 3 3 3 0 RACo linker region Phage_term_smal PF05944.12 EWM29813.1 - 0.16 12.0 0.0 2.6 8.0 0.0 2.3 2 0 0 2 2 2 0 Phage small terminase subunit FlpD PF02662.16 EWM29813.1 - 0.58 10.2 3.0 38 4.3 0.0 3.7 4 0 0 4 4 4 0 Methyl-viologen-reducing hydrogenase, delta subunit Utp21 PF04192.12 EWM29814.1 - 1.6e-42 145.6 0.0 2.3e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 EWM29814.1 - 5.4e-19 68.2 12.0 2.2e-06 28.3 0.0 8.5 10 0 0 10 10 10 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM29814.1 - 3.5e-12 46.5 0.0 0.011 16.0 0.0 6.5 4 2 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 EWM29814.1 - 0.00034 20.4 1.2 0.11 12.2 0.0 4.4 6 0 0 6 6 6 1 TUP1-like enhancer of split Nup160 PF11715.8 EWM29814.1 - 0.0042 15.8 0.2 2.1 6.9 0.1 3.7 3 1 1 4 4 4 1 Nucleoporin Nup120/160 ELYS-bb PF16687.5 EWM29814.1 - 0.13 10.8 0.0 0.28 9.8 0.0 1.6 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin Sulfatase PF00884.23 EWM29815.1 - 1.7e-46 159.1 0.0 2.6e-46 158.4 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EWM29815.1 - 1e-05 25.3 0.0 2.2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 EWM29815.1 - 0.051 12.9 0.0 0.076 12.4 0.0 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily Peptidase_S49 PF01343.18 EWM29816.1 - 2e-20 73.3 0.0 2.8e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family S49 Thioesterase PF00975.20 EWM29817.1 - 1.5e-29 103.8 0.0 2e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 EWM29817.1 - 0.00068 20.3 0.0 0.0014 19.2 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EWM29817.1 - 0.00076 19.2 0.0 0.0082 15.8 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 EWM29817.1 - 0.013 15.4 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) FSH1 PF03959.13 EWM29817.1 - 0.037 13.7 0.0 0.062 12.9 0.0 1.4 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_8 PF06259.12 EWM29817.1 - 0.043 13.4 0.1 1.6 8.4 0.0 2.4 1 1 1 2 2 2 0 Alpha/beta hydrolase Hydrolase_4 PF12146.8 EWM29817.1 - 0.077 12.3 0.0 0.32 10.2 0.0 2.0 1 1 0 1 1 1 0 Serine aminopeptidase, S33 SRAP PF02586.14 EWM29817.1 - 0.16 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 SOS response associated peptidase (SRAP) Cyclin_N PF00134.23 EWM29818.1 - 1.6e-07 31.1 0.0 0.00018 21.2 0.0 2.7 2 1 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 EWM29818.1 - 0.058 13.5 0.0 0.63 10.1 0.0 2.1 2 0 0 2 2 2 0 Cyclin, C-terminal domain TFIIB PF00382.19 EWM29818.1 - 0.14 12.2 0.1 24 5.0 0.0 2.5 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Imm27 PF15590.6 EWM29819.1 - 0.34 10.7 2.3 0.33 10.7 0.4 1.9 2 0 0 2 2 2 0 Immunity protein 27 HAD_2 PF13419.6 EWM29820.1 - 1.6e-24 87.0 0.0 2.1e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EWM29820.1 - 3.2e-12 47.2 0.0 1.3e-10 41.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EWM29820.1 - 9.6e-05 22.9 0.0 0.00016 22.2 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EWM29820.1 - 0.00011 22.3 0.0 0.013 15.6 0.0 2.6 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EWM29820.1 - 0.00013 22.0 0.0 0.00019 21.4 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like ICMT PF04140.14 EWM29821.1 - 4.4e-29 100.7 0.5 8.6e-29 99.8 0.5 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EWM29821.1 - 3.3e-13 50.0 0.4 3.3e-13 50.0 0.4 2.5 2 1 1 3 3 3 1 Phospholipid methyltransferase PP2C PF00481.21 EWM29822.1 - 2e-43 148.9 0.0 4.8e-43 147.7 0.0 1.5 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.12 EWM29822.1 - 0.00052 20.0 0.1 0.044 13.7 0.0 2.8 2 1 1 3 3 3 2 Stage II sporulation protein E (SpoIIE) PPR_2 PF13041.6 EWM29823.1 - 3.9e-31 107.0 0.0 1.1e-10 41.5 0.0 11.0 12 2 1 13 13 13 3 PPR repeat family PPR PF01535.20 EWM29823.1 - 1.2e-30 103.6 4.9 1.5e-06 28.1 0.0 13.4 15 0 0 15 15 15 5 PPR repeat PPR_3 PF13812.6 EWM29823.1 - 1.3e-17 63.6 0.0 0.00073 19.6 0.0 7.8 8 1 1 9 9 9 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 EWM29823.1 - 3.2e-14 52.3 1.0 0.00047 19.8 0.0 7.6 9 0 0 9 9 9 2 PPR repeat PPR_long PF17177.4 EWM29823.1 - 1.4e-09 37.6 2.7 0.0021 17.5 0.0 5.7 4 2 2 6 6 6 3 Pentacotripeptide-repeat region of PRORP DUF1932 PF09130.11 EWM29823.1 - 0.016 15.2 0.1 0.094 12.7 0.1 2.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1932) FANCF PF11107.8 EWM29823.1 - 0.26 10.5 1.5 0.63 9.2 1.5 1.7 1 0 0 1 1 1 0 Fanconi anemia group F protein (FANCF) TPR_14 PF13428.6 EWM29823.1 - 5.6 8.1 35.9 6.8 7.8 0.0 11.3 13 1 1 14 14 14 0 Tetratricopeptide repeat TPR_2 PF07719.17 EWM29824.1 - 6e-08 32.2 8.1 0.082 13.1 0.0 5.2 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 EWM29824.1 - 3.2e-07 30.6 12.2 0.0057 17.4 0.1 5.3 4 2 2 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 EWM29824.1 - 3.5e-07 30.1 0.0 0.031 14.6 0.0 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EWM29824.1 - 1.8e-06 27.5 2.0 1.2 9.0 0.0 4.5 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EWM29824.1 - 3.1e-06 27.0 4.0 0.34 11.2 0.0 5.0 5 1 2 7 7 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EWM29824.1 - 2.9e-05 24.5 11.4 0.0086 16.6 0.3 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 EWM29824.1 - 0.00015 21.1 7.0 0.065 12.4 0.1 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 EWM29824.1 - 0.0011 19.5 10.5 0.0016 19.0 0.6 3.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EWM29824.1 - 0.0066 16.4 8.5 1.2 9.4 0.0 5.1 7 1 0 7 7 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 EWM29824.1 - 0.011 15.6 2.2 15 5.6 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 EWM29824.1 - 0.011 15.4 0.0 2.1 8.1 0.0 3.2 3 0 0 3 3 3 0 TPR repeat ANAPC3 PF12895.7 EWM29824.1 - 0.058 13.6 1.5 6.4 7.1 0.0 3.2 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EWM29824.1 - 0.098 12.8 4.1 50 4.1 0.3 4.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EWM29824.1 - 0.39 11.5 7.8 29 5.6 0.0 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EWM29824.1 - 6.6 7.1 14.2 0.65 10.3 0.7 4.9 5 2 0 5 5 5 0 Tetratricopeptide repeat Ribosomal_60s PF00428.19 EWM29825.1 - 0.0018 18.8 10.1 0.0018 18.8 10.1 1.8 2 0 0 2 2 2 1 60s Acidic ribosomal protein PSK_trans_fac PF07704.11 EWM29825.1 - 0.2 12.4 7.7 0.65 10.8 7.7 1.9 1 0 0 1 1 1 0 Rv0623-like transcription factor DAGK_acc PF00609.19 EWM29826.1 - 1.7e-52 178.0 0.1 1.2e-33 116.7 0.0 2.2 2 0 0 2 2 2 2 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 EWM29826.1 - 3.8e-23 81.5 0.0 7.7e-23 80.5 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain ATG22 PF11700.8 EWM29826.1 - 0.064 11.9 0.4 6.7 5.2 0.0 2.1 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like FGGY_C PF02782.16 EWM29826.1 - 0.1 12.3 0.0 0.35 10.6 0.0 1.9 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain MAS20 PF02064.15 EWM29826.1 - 0.47 10.6 3.1 1.2 9.3 3.1 1.6 1 0 0 1 1 1 0 MAS20 protein import receptor Cas_Csy4 PF09618.10 EWM29826.1 - 0.6 10.2 5.9 1.4 9.0 5.9 1.5 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) TT_ORF1 PF02956.14 EWM29826.1 - 0.73 8.4 5.0 1.1 7.9 5.0 1.1 1 0 0 1 1 1 0 TT viral orf 1 REV PF00424.18 EWM29826.1 - 0.86 9.7 8.3 13 5.9 8.0 2.8 3 0 0 3 3 3 0 REV protein (anti-repression trans-activator protein) Presenilin PF01080.17 EWM29826.1 - 4.5 5.9 5.3 9.8 4.8 5.3 1.5 1 0 0 1 1 1 0 Presenilin Rrn6 PF10214.9 EWM29826.1 - 5.7 5.3 18.9 0.014 13.9 9.1 1.5 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor Baculo_PP31 PF05311.11 EWM29826.1 - 8.2 5.8 5.9 14 5.1 5.9 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) LSM PF01423.22 EWM29828.1 - 3.5e-15 55.4 0.1 4.8e-15 55.0 0.1 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EWM29828.1 - 0.13 12.0 0.1 0.13 12.0 0.1 1.6 2 0 0 2 2 2 0 Hfq protein S-methyl_trans PF02574.16 EWM29829.1 - 5.1e-48 164.2 0.2 6.1e-48 163.9 0.2 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase S-methyl_trans PF02574.16 EWM29830.1 - 1.5e-64 218.4 1.0 3.3e-36 125.5 0.1 2.0 2 0 0 2 2 2 2 Homocysteine S-methyltransferase Cuticle_3 PF11018.8 EWM29830.1 - 5.3e-06 26.8 0.1 2.9e-05 24.4 0.0 2.1 2 1 0 2 2 2 1 Pupal cuticle protein C1 Sugar_tr PF00083.24 EWM29831.1 - 4.6e-39 134.5 18.4 1.6e-26 93.2 4.0 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EWM29831.1 - 1.4e-28 99.8 44.5 3.2e-18 65.8 23.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Patatin PF01734.22 EWM29831.1 - 0.016 15.4 1.7 0.025 14.7 0.5 1.8 2 1 0 2 2 2 0 Patatin-like phospholipase TPR_16 PF13432.6 EWM29831.1 - 0.12 13.1 0.0 0.26 12.0 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat mTERF PF02536.14 EWM29832.1 - 2.3e-11 43.2 0.0 6.7e-08 31.8 0.0 3.3 2 1 2 4 4 4 2 mTERF ELO PF01151.18 EWM29833.1 - 2.7e-62 210.5 10.2 3.2e-62 210.3 10.2 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family PMBR PF09373.10 EWM29835.1 - 0.12 12.5 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 Pseudomurein-binding repeat Alkyl_sulf_dimr PF14863.6 EWM29836.1 - 3.7e-33 114.9 0.0 5.3e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.27 EWM29836.1 - 5.4e-23 82.0 0.7 1.1e-22 81.1 0.7 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EWM29836.1 - 0.00058 19.4 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Alkyl_sulf_C PF14864.6 EWM29836.1 - 0.00086 19.6 0.0 0.0016 18.7 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal HrpA_pilin PF09589.10 EWM29836.1 - 0.1 13.3 0.0 0.27 11.9 0.0 1.7 2 0 0 2 2 2 0 HrpA pilus formation protein SCP2 PF02036.17 EWM29836.1 - 0.13 12.8 0.0 0.3 11.6 0.0 1.6 1 0 0 1 1 1 0 SCP-2 sterol transfer family Aminotran_1_2 PF00155.21 EWM29837.1 - 1.5e-62 211.9 0.0 1.8e-62 211.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EWM29837.1 - 2.7e-05 23.7 0.0 4.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EWM29837.1 - 0.011 14.7 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EWM29837.1 - 0.018 13.6 0.0 0.42 9.1 0.0 2.2 1 1 1 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 EWM29837.1 - 0.033 12.9 0.0 0.056 12.2 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Bac_surface_Ag PF01103.23 EWM29838.1 - 3.6e-39 135.1 0.0 4.9e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 Surface antigen POTRA PF07244.15 EWM29838.1 - 0.00027 21.4 0.1 0.00048 20.6 0.1 1.4 1 0 0 1 1 1 1 Surface antigen variable number repeat Dak1 PF02733.17 EWM29839.1 - 7.8e-108 360.0 0.5 1.3e-107 359.3 0.5 1.4 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EWM29839.1 - 1.1e-39 136.1 1.0 2.1e-39 135.2 1.0 1.4 1 0 0 1 1 1 1 DAK2 domain DMRL_synthase PF00885.19 EWM29840.1 - 2.1e-11 43.8 2.8 3.8e-11 43.0 2.8 1.4 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase DUF1517 PF07466.11 EWM29841.1 - 1.4e-36 126.3 0.2 2e-36 125.9 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) DUF1147 PF06615.11 EWM29841.1 - 0.16 12.0 0.0 0.4 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) DUF1517 PF07466.11 EWM29842.1 - 1.5e-36 126.3 0.2 2e-36 125.8 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) DUF1147 PF06615.11 EWM29842.1 - 0.17 12.0 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) Acyl_transf_3 PF01757.22 EWM29843.1 - 1.9e-13 50.2 42.2 4.1e-13 49.1 42.2 1.6 1 1 0 1 1 1 1 Acyltransferase family DUF4381 PF14316.6 EWM29843.1 - 0.044 14.0 0.0 0.16 12.2 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) ATPase_gene1 PF09527.10 EWM29843.1 - 1.6 9.0 11.2 8.1 6.7 0.5 4.6 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter adh_short PF00106.25 EWM29844.1 - 4.1e-30 104.7 0.0 1.4e-29 103.0 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EWM29844.1 - 6e-21 75.1 0.0 1.4e-20 73.9 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM29844.1 - 1.1e-07 32.0 0.2 2.9e-07 30.6 0.0 1.7 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 EWM29844.1 - 2.8e-05 23.7 0.0 4.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EWM29844.1 - 0.023 14.1 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EWM29844.1 - 0.079 12.0 0.1 0.24 10.5 0.0 1.9 2 1 0 2 2 2 0 RmlD substrate binding domain NAD_binding_10 PF13460.6 EWM29844.1 - 0.12 12.2 0.1 0.52 10.2 0.1 1.9 1 1 0 1 1 1 0 NAD(P)H-binding DUF1776 PF08643.10 EWM29844.1 - 0.18 11.1 0.0 0.34 10.2 0.0 1.5 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Myosin_head PF00063.21 EWM29845.1 - 6.1e-194 646.0 0.0 2.1e-193 644.2 0.0 1.9 1 1 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 EWM29845.1 - 3.1e-21 73.1 138.1 0.0094 15.7 4.9 17.7 17 0 0 17 17 17 14 IQ calmodulin-binding motif PH PF00169.29 EWM29845.1 - 1.1e-11 45.2 0.2 2.8e-11 43.9 0.2 1.8 1 0 0 1 1 1 1 PH domain Ank_4 PF13637.6 EWM29845.1 - 2.1e-10 40.9 2.6 0.00039 20.9 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Aida_C2 PF14186.6 EWM29845.1 - 8.1e-10 38.5 0.0 2.2e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 Cytoskeletal adhesion Ank_5 PF13857.6 EWM29845.1 - 8.8e-10 38.6 5.7 0.026 14.9 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EWM29845.1 - 2.3e-07 31.3 0.8 3.7e-05 24.2 0.0 3.3 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.30 EWM29845.1 - 1.8e-05 25.0 2.6 0.28 11.7 0.0 4.9 4 1 0 4 4 4 2 Ankyrin repeat PH_11 PF15413.6 EWM29845.1 - 0.00016 22.1 0.1 0.00068 20.0 0.1 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain Ank_3 PF13606.6 EWM29845.1 - 0.07 13.7 5.9 16 6.4 0.0 5.7 6 0 0 6 6 6 0 Ankyrin repeat BCMA-Tall_bind PF09257.10 EWM29845.1 - 0.098 12.8 0.1 0.26 11.4 0.1 1.7 1 0 0 1 1 1 0 BCMA, TALL-1 binding UQ_con PF00179.26 EWM29846.1 - 7.1e-43 145.6 0.0 8e-43 145.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EWM29846.1 - 0.068 12.9 0.0 0.079 12.7 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family B DEAD PF00270.29 EWM29847.1 - 8.7e-42 142.9 0.0 1.3e-41 142.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EWM29847.1 - 2.3e-29 102.0 0.0 1.3e-28 99.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EWM29847.1 - 0.00013 22.0 0.0 0.00021 21.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Acetyltransf_13 PF13880.6 EWM29847.1 - 0.16 12.0 0.0 0.67 10.0 0.0 2.1 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase DUF608 PF04685.13 EWM29848.1 - 4.5e-143 476.8 2.9 1.5e-142 475.1 2.9 1.7 1 1 0 1 1 1 1 Glycosyl-hydrolase family 116, catalytic region Glyco_hydr_116N PF12215.8 EWM29848.1 - 1.8e-93 313.5 0.0 1.3e-76 258.0 0.0 2.4 2 0 0 2 2 2 2 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term DUF5127 PF17168.4 EWM29848.1 - 0.0074 16.1 0.0 0.017 14.9 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF5127) MFS_2 PF13347.6 EWM29849.1 - 4.6e-17 61.7 19.0 4.6e-17 61.7 19.0 1.6 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_1 PF07690.16 EWM29849.1 - 8.4e-09 34.8 19.0 8.4e-09 34.8 19.0 2.4 2 1 1 3 3 3 1 Major Facilitator Superfamily tRNA-synt_1g PF09334.11 EWM29850.1 - 9.5e-110 367.0 0.1 1.7e-64 218.0 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EWM29850.1 - 7.6e-27 93.8 1.9 8.7e-13 47.4 0.0 3.9 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 EWM29850.1 - 7.9e-13 48.4 0.0 3.1e-07 30.0 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Cyclin_N PF00134.23 EWM29851.1 - 2.4e-05 24.1 0.0 5.1e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Cyclin, N-terminal domain DUF2462 PF09495.10 EWM29852.1 - 0.011 16.4 12.7 0.011 16.4 12.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2462) DUF2533 PF10752.9 EWM29852.1 - 0.044 14.2 2.2 0.065 13.7 1.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2533) Peptidase_M15_2 PF05951.13 EWM29852.1 - 0.066 12.9 0.3 0.093 12.4 0.3 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) Spore_III_AB PF09548.10 EWM29852.1 - 0.078 13.1 3.3 0.082 13.0 3.3 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) PseudoU_synth_2 PF00849.22 EWM29853.1 - 1.8e-28 99.7 0.0 2.3e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase YccV-like PF08755.11 EWM29854.1 - 1.3e-27 96.2 0.0 8.9e-17 61.4 0.0 2.4 2 0 0 2 2 2 2 Hemimethylated DNA-binding protein YccV like Herpes_UL49_2 PF04823.12 EWM29854.1 - 0.15 12.1 0.1 0.42 10.7 0.1 1.7 1 0 0 1 1 1 0 Herpesvirus UL49 tegument protein Complex1_LYR PF05347.15 EWM29854.1 - 0.2 11.7 7.0 0.82 9.8 0.1 3.7 4 0 0 4 4 4 0 Complex 1 protein (LYR family) Bromodomain PF00439.25 EWM29855.1 - 1.5e-10 41.0 0.0 3.1e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Bromodomain COBRA1 PF06209.13 EWM29855.1 - 5.1e-09 35.5 0.1 0.00017 20.6 0.0 2.6 3 0 0 3 3 3 2 Cofactor of BRCA1 (COBRA1) RNA_pol_Rbc25 PF08292.12 EWM29856.1 - 2.2e-31 108.8 0.5 6.4e-30 104.0 0.5 2.2 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 EWM29856.1 - 7.2e-14 51.9 0.1 1.2e-13 51.2 0.1 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 EWM29856.1 - 0.11 12.8 0.2 0.31 11.4 0.0 1.8 2 0 0 2 2 2 0 S1 RNA binding domain HORMA PF02301.18 EWM29857.1 - 4.4e-22 78.7 0.1 6e-22 78.3 0.1 1.2 1 0 0 1 1 1 1 HORMA domain ATG13 PF10033.9 EWM29857.1 - 0.01 15.5 0.1 0.076 12.7 0.1 2.0 2 0 0 2 2 2 0 Autophagy-related protein 13 ATG101 PF07855.12 EWM29857.1 - 0.047 13.7 0.2 0.17 11.8 0.2 2.0 1 1 0 1 1 1 0 Autophagy-related protein 101 zf-DNL PF05180.12 EWM29858.1 - 2.3e-14 53.0 0.0 4.5e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 DNL zinc finger Elf1 PF05129.13 EWM29858.1 - 0.035 14.1 0.2 0.078 13.0 0.2 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like URO-D PF01208.17 EWM29859.1 - 1.7e-109 366.1 0.0 2e-109 365.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Chloroa_b-bind PF00504.21 EWM29860.1 - 2.4e-30 106.2 0.0 3e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein FA_hydroxylase PF04116.13 EWM29861.1 - 5e-23 81.9 17.4 5e-23 81.9 17.4 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Clathrin PF00637.20 EWM29862.1 - 4e-07 30.0 0.0 8.8e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Region in Clathrin and VPS Aminotran_5 PF00266.19 EWM29863.1 - 1.3e-15 57.3 0.0 5e-14 52.0 0.0 2.4 3 0 0 3 3 3 2 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EWM29863.1 - 0.012 15.0 0.7 0.25 10.6 0.5 2.9 3 1 0 3 3 3 0 DegT/DnrJ/EryC1/StrS aminotransferase family A_deaminase PF00962.22 EWM29864.1 - 3.5e-48 164.6 0.0 1.6e-29 103.3 0.0 2.1 2 0 0 2 2 2 2 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 EWM29864.1 - 0.0016 17.8 0.2 0.0016 17.8 0.2 1.5 2 0 0 2 2 2 1 Amidohydrolase family Methyltransf_11 PF08241.12 EWM29865.1 - 1.4e-22 80.2 0.0 2.2e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM29865.1 - 2e-17 63.6 0.0 3.4e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EWM29865.1 - 1e-15 57.9 0.0 1.5e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM29865.1 - 9.1e-11 41.8 0.0 1.3e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EWM29865.1 - 2.7e-10 40.9 0.0 4.4e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EWM29865.1 - 2e-09 37.1 0.0 2.9e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.14 EWM29865.1 - 0.0017 17.8 0.0 0.0026 17.2 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_29 PF03141.16 EWM29865.1 - 0.0028 16.3 0.0 0.0036 15.9 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MetW PF07021.12 EWM29865.1 - 0.015 14.9 0.0 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.15 EWM29865.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Acyltransferase PF01553.21 EWM29867.1 - 2e-13 50.1 0.0 7.1e-13 48.3 0.0 1.9 1 1 0 1 1 1 1 Acyltransferase HlyIII PF03006.20 EWM29868.1 - 8.3e-31 107.4 23.5 1.2e-30 107.0 23.5 1.2 1 0 0 1 1 1 1 Haemolysin-III related LRR_6 PF13516.6 EWM29868.1 - 5.5e-08 32.2 2.8 0.63 10.2 0.0 4.4 4 0 0 4 4 4 3 Leucine Rich repeat LRR_4 PF12799.7 EWM29868.1 - 0.2 12.1 1.0 1.9 9.0 0.1 2.6 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) Fer2 PF00111.27 EWM29870.1 - 0.00029 20.8 0.2 0.00042 20.2 0.2 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 EWM29870.1 - 0.013 15.5 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain PIG-F PF06699.11 EWM29871.1 - 1.5e-19 70.9 7.2 2e-19 70.4 7.2 1.4 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F TauE PF01925.19 EWM29871.1 - 3.3 7.3 17.1 0.14 11.8 1.9 3.3 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE Pyr_redox_2 PF07992.14 EWM29872.1 - 6.2e-16 58.5 0.0 4.5e-09 36.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EWM29872.1 - 0.036 12.9 0.4 0.36 9.6 0.0 2.5 3 0 0 3 3 3 0 Tryptophan halogenase DAO PF01266.24 EWM29872.1 - 0.12 12.0 2.8 1.5 8.3 2.8 2.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EWM29872.1 - 0.13 12.3 0.0 5.1 7.1 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Ank_5 PF13857.6 EWM29874.1 - 4.3e-17 62.0 0.3 2.5e-07 30.8 0.0 3.2 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EWM29874.1 - 1.2e-16 60.8 0.0 7.7e-08 32.7 0.0 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EWM29874.1 - 9e-14 51.2 0.1 0.00089 19.6 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EWM29874.1 - 2.2e-10 41.0 0.0 1.5e-05 25.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EWM29874.1 - 2.3e-10 39.8 0.2 0.15 12.7 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat FAST_1 PF06743.15 EWM29875.1 - 0.00027 20.8 0.2 4.7 7.2 0.0 4.1 4 1 0 4 4 4 2 FAST kinase-like protein, subdomain 1 RAP PF08373.10 EWM29875.1 - 0.13 12.4 0.0 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 RAP domain Lactamase_B PF00753.27 EWM29876.1 - 3e-14 53.5 0.4 4.1e-13 49.8 0.4 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF442 PF04273.13 EWM29876.1 - 0.0088 16.1 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Putative phosphatase (DUF442) Lactamase_B_2 PF12706.7 EWM29876.1 - 0.08 12.4 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Beta-lactamase superfamily domain TraB PF01963.17 EWM29877.1 - 1.8e-17 64.2 0.0 9.2e-09 35.6 0.0 2.1 2 0 0 2 2 2 2 TraB family WD40 PF00400.32 EWM29878.1 - 0.028 15.3 1.4 10 7.2 0.0 4.0 4 0 0 4 4 4 0 WD domain, G-beta repeat Nup160 PF11715.8 EWM29878.1 - 0.13 10.9 0.1 0.68 8.5 0.0 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Cyt-b5 PF00173.28 EWM29879.1 - 2.7e-10 40.3 0.0 5e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IQ PF00612.27 EWM29879.1 - 0.23 11.3 0.8 0.54 10.2 0.8 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif Tam41_Mmp37 PF09139.11 EWM29880.1 - 7.9e-101 337.7 0.0 9.3e-101 337.5 0.0 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial Ribosomal_S4e PF00900.20 EWM29882.1 - 2e-27 94.9 1.4 4.5e-27 93.8 0.1 2.2 3 0 0 3 3 3 1 Ribosomal family S4e 40S_S4_C PF16121.5 EWM29882.1 - 8.1e-26 89.4 0.1 1.4e-25 88.7 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 EWM29882.1 - 9.9e-21 73.6 5.3 1.8e-20 72.7 5.3 1.4 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 EWM29882.1 - 1.8e-09 37.1 0.0 3.4e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 EWM29882.1 - 3.5e-06 26.8 3.0 5.5e-06 26.2 0.0 2.8 4 0 0 4 4 4 1 KOW motif DUF3912 PF13051.6 EWM29882.1 - 0.052 13.8 0.6 0.2 12.0 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3912) zf-HC5HC2H_2 PF13832.6 EWM29883.1 - 2.2e-18 66.4 2.0 3.3e-18 65.9 2.0 1.3 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EWM29883.1 - 2.4e-10 40.5 1.2 1.2e-09 38.3 0.3 2.1 2 0 0 2 2 2 1 PHD-like zinc-binding domain C1_2 PF03107.16 EWM29883.1 - 3.2 8.1 9.3 0.42 11.0 0.4 3.4 4 0 0 4 4 4 0 C1 domain Metallophos PF00149.28 EWM29884.1 - 3.5e-10 40.7 0.0 6.3e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Mre11_DNA_bind PF04152.14 EWM29884.1 - 4.6e-08 33.6 0.0 6.8e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos_2 PF12850.7 EWM29884.1 - 7.9e-05 22.9 0.0 0.0012 19.1 0.0 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DNA_primase_lrg PF04104.14 EWM29885.1 - 4.2e-74 249.3 0.0 6.8e-74 248.6 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Phosphodiest PF01663.22 EWM29886.1 - 5.8e-10 39.3 0.0 1.5e-09 38.0 0.0 1.6 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF5136 PF17199.4 EWM29887.1 - 0.082 12.6 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF5136) Methyltransf_21 PF05050.12 EWM29888.1 - 1.2e-11 44.9 0.0 1.8e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain Voltage_CLC PF00654.20 EWM29889.1 - 8e-73 245.7 23.4 8e-73 245.7 23.4 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EWM29889.1 - 0.0095 16.4 0.1 1.3 9.5 0.0 2.5 2 0 0 2 2 2 2 CBS domain UEV PF05743.13 EWM29890.1 - 1.8e-34 118.2 0.0 2.5e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 UEV domain UQ_con PF00179.26 EWM29890.1 - 4.1e-06 26.5 0.1 6.6e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF3573 PF12097.8 EWM29891.1 - 0.093 11.5 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) STELLO PF03385.17 EWM29892.1 - 8.5e-18 64.3 0.0 1.4e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 STELLO glycosyltransferases Glyco_tranf_2_4 PF13704.6 EWM29892.1 - 2.9e-06 27.7 0.0 7.8e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 CDK2AP PF09806.9 EWM29893.1 - 0.63 10.1 5.3 1.3 9.0 5.3 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein CDK2AP PF09806.9 EWM29894.1 - 0.36 10.9 4.5 0.75 9.8 4.5 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Fer2 PF00111.27 EWM29895.1 - 1.4e-08 34.5 0.5 3.5e-08 33.3 0.5 1.6 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF309 PF03745.14 EWM29895.1 - 1.2 8.8 3.9 0.34 10.6 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF309) FAA_hydrolase PF01557.18 EWM29896.1 - 5.7e-56 189.6 0.0 6.5e-56 189.4 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Glutaredoxin PF00462.24 EWM29897.1 - 1.4e-38 130.9 0.0 3.1e-18 65.7 0.0 2.5 2 0 0 2 2 2 2 Glutaredoxin Thioredoxin PF00085.20 EWM29897.1 - 1.3e-09 37.9 0.0 5.9e-09 35.8 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin SH3BGR PF04908.15 EWM29897.1 - 5.6e-05 23.2 0.0 0.39 10.9 0.0 2.4 2 0 0 2 2 2 2 SH3-binding, glutamic acid-rich protein HyaE PF07449.11 EWM29897.1 - 0.0066 16.4 0.3 4 7.4 0.0 3.6 3 2 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin_2 PF13098.6 EWM29897.1 - 0.043 14.3 0.0 0.92 10.0 0.0 2.8 3 0 0 3 3 3 0 Thioredoxin-like domain GerD PF17898.1 EWM29897.1 - 0.049 13.6 0.0 3.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Spore germination GerD central core domain PBP_sp32 PF07222.12 EWM29898.1 - 0.011 15.1 0.1 0.011 15.1 0.1 1.5 2 0 0 2 2 2 0 Proacrosin binding protein sp32 Robl_LC7 PF03259.17 EWM29899.1 - 9e-14 51.0 0.0 1.1e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 EWM29899.1 - 0.0063 16.4 0.0 0.0081 16.1 0.0 1.2 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 DUF3377 PF11857.8 EWM29899.1 - 0.087 12.8 0.2 0.17 11.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Robl_LC7 PF03259.17 EWM29900.1 - 9e-14 51.0 0.0 1.1e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 EWM29900.1 - 0.0063 16.4 0.0 0.0081 16.1 0.0 1.2 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 DUF3377 PF11857.8 EWM29900.1 - 0.087 12.8 0.2 0.17 11.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Robl_LC7 PF03259.17 EWM29901.1 - 9e-14 51.0 0.0 1.1e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 EWM29901.1 - 0.0063 16.4 0.0 0.0081 16.1 0.0 1.2 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 DUF3377 PF11857.8 EWM29901.1 - 0.087 12.8 0.2 0.17 11.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) PQQ_2 PF13360.6 EWM29902.1 - 1.8e-10 40.8 0.4 0.00021 21.0 0.0 2.5 1 1 1 2 2 2 2 PQQ-like domain WD40 PF00400.32 EWM29902.1 - 4.7e-09 36.7 7.1 0.016 16.1 0.0 5.9 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM29902.1 - 1.2e-07 32.0 0.1 0.26 11.6 0.0 4.8 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EWM29902.1 - 0.00022 21.6 7.6 1.7 9.2 0.0 5.6 6 0 0 6 6 6 2 PQQ-like domain PQQ PF01011.21 EWM29902.1 - 0.00026 20.8 0.2 0.021 14.8 0.0 3.4 4 0 0 4 4 4 1 PQQ enzyme repeat NUP214 PF16755.5 EWM29902.1 - 0.12 11.6 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 Methyltransf_21 PF05050.12 EWM29904.1 - 1.5e-10 41.4 0.0 2.3e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_23 PF13489.6 EWM29904.1 - 0.0074 16.1 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RelB PF04221.12 EWM29904.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 RelB antitoxin Glycos_transf_1 PF00534.20 EWM29905.1 - 2.4e-31 108.6 0.0 3.9e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EWM29905.1 - 2.2e-16 60.5 0.0 4.2e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EWM29905.1 - 1.2e-10 41.7 1.2 3.2e-10 40.3 1.2 1.7 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 EWM29905.1 - 6.1e-05 23.3 0.0 0.00017 21.9 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EWM29905.1 - 0.00076 20.0 4.4 0.0013 19.2 2.6 2.1 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain GHMP_kinases_N PF00288.26 EWM29906.1 - 1.4e-11 44.5 0.4 4e-11 43.0 0.4 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EWM29906.1 - 2e-06 28.1 0.0 5.1e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Hist_deacetyl PF00850.19 EWM29907.1 - 3.6e-82 276.3 0.0 4.4e-82 276.0 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain OCRE PF17780.1 EWM29907.1 - 0.051 13.6 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 OCRE domain DUF1115 PF06544.12 EWM29908.1 - 4.4e-10 39.8 0.0 7.3e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) RWD PF05773.22 EWM29908.1 - 0.00039 20.7 0.0 0.00092 19.5 0.0 1.6 1 1 0 1 1 1 1 RWD domain Acylphosphatase PF00708.18 EWM29908.1 - 0.067 13.6 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Acylphosphatase UvrC_HhH_N PF08459.11 EWM29908.1 - 0.087 12.7 0.0 0.14 12.1 0.0 1.5 1 1 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal JmjC PF02373.22 EWM29909.1 - 7.3e-37 126.3 0.5 1.5e-36 125.3 0.5 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 EWM29909.1 - 6.1e-13 48.5 1.6 6.5e-13 48.4 0.2 1.8 2 0 0 2 2 2 1 jmjN domain zf-C5HC2 PF02928.16 EWM29909.1 - 4e-10 39.9 10.2 4e-10 39.9 10.2 1.9 2 0 0 2 2 2 1 C5HC2 zinc finger Herpes_BLLF1 PF05109.13 EWM29909.1 - 2.6 5.9 7.6 3.6 5.4 7.6 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) CDH PF02611.15 EWM29910.1 - 1.7e-06 27.8 0.4 8.7e-05 22.2 0.4 2.2 1 1 0 1 1 1 1 CDP-diacylglycerol pyrophosphatase CDH PF02611.15 EWM29911.1 - 2.1e-06 27.5 0.4 9.9e-05 22.1 0.4 2.2 1 1 0 1 1 1 1 CDP-diacylglycerol pyrophosphatase NCA2 PF08637.10 EWM29912.1 - 1.4e-48 165.5 0.9 7.4e-44 150.1 0.3 2.3 2 0 0 2 2 2 2 ATP synthase regulation protein NCA2 FAST_1 PF06743.15 EWM29914.1 - 1.3e-13 50.7 4.5 0.0044 16.9 0.0 7.0 8 0 0 8 8 8 4 FAST kinase-like protein, subdomain 1 RAP PF08373.10 EWM29914.1 - 0.001 19.1 0.0 0.0026 17.8 0.0 1.7 1 0 0 1 1 1 1 RAP domain SUIM_assoc PF16619.5 EWM29915.1 - 0.059 13.4 10.1 0.73 9.9 4.4 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 ATG101 PF07855.12 EWM29915.1 - 0.33 10.9 1.8 7.5 6.5 0.0 2.7 3 0 0 3 3 3 0 Autophagy-related protein 101 YihI PF04220.12 EWM29916.1 - 0.052 13.3 0.4 0.061 13.0 0.4 1.2 1 0 0 1 1 1 0 Der GTPase activator (YihI) PK PF00224.21 EWM29917.1 - 1.3e-121 405.7 0.2 2.1e-121 405.1 0.2 1.3 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EWM29917.1 - 7.1e-22 77.9 0.0 2.2e-21 76.2 0.0 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EWM29917.1 - 0.0038 16.4 0.4 0.015 14.4 0.2 2.0 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family p450 PF00067.22 EWM29918.1 - 1.2e-25 90.3 0.0 1.6e-15 56.8 0.0 2.4 3 0 0 3 3 3 2 Cytochrome P450 RRM_1 PF00076.22 EWM29919.1 - 1.3e-17 63.4 0.0 2.3e-12 46.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EWM29919.1 - 0.016 15.3 0.0 0.052 13.7 0.0 1.9 1 1 0 1 1 1 0 RNA recognition motif PBP PF01161.20 EWM29920.1 - 9.5e-17 61.6 0.1 1.4e-16 61.0 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Kinesin PF00225.23 EWM29922.1 - 3.7e-92 308.8 0.8 5.1e-92 308.3 0.8 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EWM29922.1 - 7.7e-20 71.4 0.0 4e-16 59.3 0.0 2.5 2 0 0 2 2 2 2 Microtubule binding PH PF00169.29 EWM29922.1 - 1.9e-05 25.1 0.0 6.9e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 PH domain Kinesin_assoc PF16183.5 EWM29922.1 - 0.0055 16.9 0.9 0.012 15.8 0.0 2.0 2 0 0 2 2 2 1 Kinesin-associated Bac_DnaA PF00308.18 EWM29922.1 - 0.18 11.6 0.0 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 Bacterial dnaA protein tRNA-synt_1b PF00579.25 EWM29924.1 - 2.4e-56 191.2 0.0 3e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA-synt_1b PF00579.25 EWM29925.1 - 2.4e-56 191.2 0.0 3.5e-56 190.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TPR_10 PF13374.6 EWM29927.1 - 8e-06 25.6 1.5 0.2 11.6 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EWM29927.1 - 1e-05 25.2 0.5 0.31 11.3 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EWM29927.1 - 1.7e-05 24.5 0.3 0.2 11.7 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EWM29927.1 - 0.00019 21.7 2.6 0.24 11.7 0.2 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EWM29927.1 - 0.0031 17.2 0.0 1.1 9.0 0.1 3.1 3 0 0 3 3 3 1 TPR repeat MIT PF04212.18 EWM29927.1 - 0.0066 16.5 0.0 0.25 11.4 0.0 2.8 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 EWM29927.1 - 0.064 13.5 0.0 31 5.1 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EWM29927.1 - 0.12 12.2 0.0 2.6 8.0 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EWM29927.1 - 0.17 12.8 9.5 4 8.5 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 EWM29927.1 - 2.3 8.9 9.5 0.67 10.7 0.4 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat AMP-binding PF00501.28 EWM29929.1 - 2.5e-59 201.0 0.1 3.5e-59 200.5 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EWM29929.1 - 8.2e-51 172.6 0.0 1.4e-50 171.9 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 EWM29929.1 - 8.6e-10 38.8 0.1 1.9e-09 37.7 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 EWM29929.1 - 7.9e-07 28.8 0.1 1.1e-05 25.1 0.1 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EWM29929.1 - 0.0027 16.7 0.0 0.037 13.0 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 EWM29929.1 - 0.065 14.2 0.3 0.32 12.0 0.0 2.3 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain GDP_Man_Dehyd PF16363.5 EWM29929.1 - 0.086 12.2 0.3 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DNA_primase_S PF01896.19 EWM29932.1 - 5.6e-55 186.1 0.0 9.6e-55 185.4 0.0 1.4 1 0 0 1 1 1 1 DNA primase small subunit Glutaredoxin PF00462.24 EWM29934.1 - 3.1e-18 65.8 0.1 6.7e-18 64.7 0.1 1.6 1 0 0 1 1 1 1 Glutaredoxin Glyoxalase PF00903.25 EWM29934.1 - 7e-08 32.7 0.0 0.0098 16.1 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EWM29934.1 - 3.7e-06 27.7 1.0 0.00022 22.0 0.3 2.6 2 1 0 2 2 2 1 Glyoxalase-like domain GST_N_3 PF13417.6 EWM29934.1 - 0.005 17.2 0.0 0.011 16.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF836 PF05768.14 EWM29934.1 - 0.018 15.4 0.0 0.035 14.5 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) GST_N_2 PF13409.6 EWM29934.1 - 0.023 15.0 0.0 0.048 14.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.6 EWM29934.1 - 0.04 14.4 0.0 0.088 13.3 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain DSBA PF01323.20 EWM29934.1 - 0.13 12.0 0.1 0.28 11.0 0.0 1.5 2 0 0 2 2 2 0 DSBA-like thioredoxin domain ADP_PFK_GK PF04587.15 EWM29935.1 - 0.13 10.8 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region RNA_pol_3_Rpc31 PF11705.8 EWM29935.1 - 0.22 11.8 11.3 0.32 11.2 11.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Tub_N PF16322.5 EWM29935.1 - 0.57 10.5 12.1 0.78 10.1 12.1 1.1 1 0 0 1 1 1 0 Tubby N-terminal Paf1 PF03985.13 EWM29935.1 - 1.4 7.8 19.4 1.8 7.5 19.4 1.1 1 0 0 1 1 1 0 Paf1 DUF4820 PF16091.5 EWM29935.1 - 1.6 8.1 5.0 2.3 7.5 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) NOA36 PF06524.12 EWM29935.1 - 3.1 7.1 9.3 3.9 6.7 9.3 1.1 1 0 0 1 1 1 0 NOA36 protein RR_TM4-6 PF06459.12 EWM29935.1 - 3.8 7.3 7.2 4.9 6.9 7.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pinin_SDK_N PF04697.13 EWM29935.1 - 5.3 7.7 13.4 10 6.8 13.4 1.5 1 0 0 1 1 1 0 pinin/SDK conserved region Nop14 PF04147.12 EWM29935.1 - 6.8 4.8 14.2 8.2 4.5 14.2 1.0 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.25 EWM29936.1 - 4.2e-62 209.9 0.0 5.1e-62 209.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM29936.1 - 1.6e-25 89.9 0.0 2.3e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EWM29936.1 - 2.7e-06 26.9 0.0 4.7e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EWM29936.1 - 0.025 13.5 0.0 0.038 12.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain CDC4_D PF16856.5 EWM29936.1 - 0.065 13.1 0.0 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 Cell division control protein 4 dimerisation domain ADH_N_2 PF16884.5 EWM29936.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.7 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase APH PF01636.23 EWM29936.1 - 0.13 12.1 0.2 1.1 9.1 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family PIP49_C PF12260.8 EWM29936.1 - 0.22 11.1 0.1 0.38 10.4 0.1 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Fructosamin_kin PF03881.14 EWM29937.1 - 2.2e-65 220.7 0.0 3.3e-65 220.2 0.0 1.2 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 EWM29937.1 - 9.4e-13 48.6 0.1 2.1e-12 47.5 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Peptidase_C97 PF05903.14 EWM29939.1 - 9.3e-21 74.2 0.0 1.3e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF5090 PF17009.5 EWM29940.1 - 7.2 6.5 7.9 5.3 7.0 5.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) Abhydrolase_6 PF12697.7 EWM29941.1 - 3.8e-18 66.9 4.4 3.8e-18 66.9 4.4 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EWM29941.1 - 3.5e-16 59.6 0.3 1.6e-15 57.4 0.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EWM29941.1 - 3e-11 43.1 0.1 4e-10 39.4 0.1 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EWM29941.1 - 0.19 11.4 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Chlorophyllase2 PF12740.7 EWM29941.1 - 0.21 10.5 0.0 0.3 10.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Voltage_CLC PF00654.20 EWM29943.1 - 3.5e-22 79.1 5.7 3.5e-22 79.1 5.7 2.0 2 1 1 3 3 3 1 Voltage gated chloride channel GHMP_kinases_N PF00288.26 EWM29944.1 - 1.7e-06 28.2 0.2 5.2e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EWM29944.1 - 0.00065 20.0 0.2 0.0017 18.7 0.0 1.8 2 0 0 2 2 2 1 GHMP kinases C terminal GidB PF02527.15 EWM29945.1 - 9.3e-33 113.1 0.0 1.3e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.6 EWM29945.1 - 4.2e-07 29.9 0.0 6.9e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EWM29945.1 - 0.00046 19.8 0.0 0.00074 19.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EWM29945.1 - 0.0016 19.1 0.0 0.0029 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EWM29945.1 - 0.016 15.0 0.0 0.06 13.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.17 EWM29945.1 - 0.021 14.3 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_12 PF08242.12 EWM29945.1 - 0.028 15.1 0.0 0.063 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EWM29945.1 - 0.15 11.4 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 EWM29945.1 - 0.2 11.4 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Y_phosphatase2 PF03162.13 EWM29946.1 - 0.012 15.3 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EWM29946.1 - 0.066 13.2 0.3 0.11 12.4 0.3 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Ribosomal_60s PF00428.19 EWM29947.1 - 4.8e-15 55.9 3.0 6.3e-15 55.5 3.0 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein eIF3_subunit PF08597.10 EWM29947.1 - 0.0021 18.0 0.5 0.003 17.5 0.5 1.2 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Patatin PF01734.22 EWM29948.1 - 7e-09 36.2 1.1 1.6e-08 35.0 1.1 1.7 1 1 0 1 1 1 1 Patatin-like phospholipase FliD_C PF07195.12 EWM29949.1 - 0.00057 19.4 0.4 0.0007 19.1 0.4 1.2 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 C-terminus ApoLp-III PF07464.11 EWM29949.1 - 0.00079 19.5 3.0 0.0012 19.0 3.0 1.2 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) Flot PF15975.5 EWM29949.1 - 0.047 13.9 4.6 0.074 13.2 4.6 1.3 1 0 0 1 1 1 0 Flotillin ATP-synt_B PF00430.18 EWM29949.1 - 0.28 11.3 6.9 0.49 10.5 6.9 1.4 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF3987 PF13148.6 EWM29949.1 - 0.52 9.3 3.7 0.68 8.9 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) FliD_C PF07195.12 EWM29950.1 - 0.0016 17.9 0.9 0.0016 17.9 0.9 2.0 1 1 1 2 2 2 1 Flagellar hook-associated protein 2 C-terminus ApoLp-III PF07464.11 EWM29950.1 - 0.002 18.2 14.6 0.0071 16.4 10.7 2.1 1 1 1 2 2 2 1 Apolipophorin-III precursor (apoLp-III) DUF4407 PF14362.6 EWM29950.1 - 0.073 12.4 16.9 0.085 12.2 16.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ALMT PF11744.8 EWM29950.1 - 0.16 10.7 8.4 0.19 10.5 8.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter LMBR1 PF04791.16 EWM29950.1 - 0.49 9.2 4.1 0.56 9.1 4.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Mitofilin PF09731.9 EWM29950.1 - 0.71 8.6 24.4 1.1 8.0 24.4 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein VSG_B PF13206.6 EWM29950.1 - 1.6 7.9 21.0 2 7.6 21.0 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain V_ATPase_I PF01496.19 EWM29950.1 - 1.9 6.3 5.6 2.2 6.1 5.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SAPS PF04499.15 EWM29950.1 - 2.1 7.0 10.0 2.5 6.8 10.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein AAA_11 PF13086.6 EWM29950.1 - 2.5 7.8 11.7 3.2 7.5 11.7 1.1 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.8 EWM29950.1 - 2.7 5.4 20.3 3.1 5.2 20.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FUSC PF04632.12 EWM29950.1 - 2.7 6.4 5.3 3.5 6.0 5.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Presenilin PF01080.17 EWM29950.1 - 3 6.5 11.2 3.7 6.2 11.2 1.2 1 0 0 1 1 1 0 Presenilin Uso1_p115_C PF04871.13 EWM29950.1 - 6 7.2 30.5 8.9 6.7 22.3 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF883 PF05957.13 EWM29950.1 - 6.6 7.4 27.2 12 6.6 6.3 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 EWM29950.1 - 6.9 7.3 28.2 1.8e+04 -7.4 28.2 3.1 1 1 0 1 1 0 0 YtxH-like protein VIR_N PF15912.5 EWM29950.1 - 8.5 5.9 8.8 12 5.4 8.8 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Neur_chan_memb PF02932.16 EWM29950.1 - 9.2 6.2 6.6 11 6.0 6.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ApoLp-III PF07464.11 EWM29951.1 - 0.001 19.2 11.4 0.003 17.7 11.4 1.7 1 1 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) FliD_C PF07195.12 EWM29951.1 - 0.0014 18.1 0.8 0.0014 18.1 0.8 1.9 1 1 1 2 2 2 1 Flagellar hook-associated protein 2 C-terminus DUF4407 PF14362.6 EWM29951.1 - 0.032 13.6 14.3 0.037 13.4 14.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Apolipoprotein PF01442.18 EWM29951.1 - 0.051 13.5 16.5 0.15 11.9 16.7 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain ALMT PF11744.8 EWM29951.1 - 0.12 11.2 6.0 0.13 11.0 6.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter LMBR1 PF04791.16 EWM29951.1 - 0.15 10.9 2.6 0.17 10.7 2.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF966 PF06136.13 EWM29951.1 - 0.24 11.1 9.8 0.27 10.9 9.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Mitofilin PF09731.9 EWM29951.1 - 0.32 9.8 19.2 0.43 9.3 19.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF3584 PF12128.8 EWM29951.1 - 0.32 8.4 17.0 0.39 8.2 17.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.11 EWM29951.1 - 0.36 9.7 10.4 0.46 9.3 10.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FUSC PF04632.12 EWM29951.1 - 0.99 7.9 5.4 1.3 7.5 5.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family V_ATPase_I PF01496.19 EWM29951.1 - 1 7.2 2.9 1.2 7.0 2.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family XRN_M PF17846.1 EWM29951.1 - 1.4 7.8 6.4 1.6 7.6 6.4 1.0 1 0 0 1 1 1 0 Xrn1 helical domain Exonuc_VII_L PF02601.15 EWM29951.1 - 1.7 8.2 13.1 4.1 6.9 13.1 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit VSG_B PF13206.6 EWM29951.1 - 1.7 7.8 17.5 2.2 7.5 17.5 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain SAPS PF04499.15 EWM29951.1 - 1.9 7.1 8.8 2.2 7.0 8.8 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MAD PF05557.13 EWM29951.1 - 2.1 6.6 13.8 2.5 6.4 13.8 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein DDHD PF02862.17 EWM29951.1 - 2.2 8.4 5.5 2.9 8.0 5.5 1.2 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 EWM29951.1 - 2.5 6.8 9.0 3 6.5 9.0 1.2 1 0 0 1 1 1 0 Presenilin Borrelia_P83 PF05262.11 EWM29951.1 - 3 6.3 22.3 3.7 5.9 22.3 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Neur_chan_memb PF02932.16 EWM29951.1 - 3.7 7.5 4.2 4.2 7.3 4.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF883 PF05957.13 EWM29951.1 - 4.8 7.9 24.0 9.6 6.9 7.1 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Hid1 PF12722.7 EWM29951.1 - 7 4.6 8.1 8 4.5 8.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TMPIT PF07851.13 EWM29951.1 - 7.7 5.7 9.5 36 3.5 9.5 1.9 1 1 0 1 1 1 0 TMPIT-like protein Rieske PF00355.26 EWM29953.1 - 3.5e-12 46.1 0.0 4.7e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 EWM29953.1 - 3.1e-09 36.7 0.0 3.7e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain IBR PF01485.21 EWM29954.1 - 1.7e-10 40.9 30.8 2e-07 31.1 4.0 3.7 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 EWM29954.1 - 0.017 14.9 5.5 0.017 14.9 5.5 3.8 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EWM29954.1 - 0.025 14.9 6.0 0.025 14.9 6.0 4.0 3 0 0 3 3 3 0 Ring finger domain Baculo_ME53 PF06061.11 EWM29954.1 - 0.081 12.1 1.2 0.14 11.3 1.2 1.3 1 0 0 1 1 1 0 Baculoviridae ME53 FH2 PF02181.23 EWM29955.1 - 1.8e-15 56.9 0.0 2.4e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain CAP_N PF01213.19 EWM29955.1 - 0.06 12.8 0.8 0.083 12.4 0.8 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Smr PF01713.21 EWM29956.1 - 6.3e-09 36.1 1.5 1.6e-08 34.8 1.5 1.7 1 1 0 1 1 1 1 Smr domain FH2 PF02181.23 EWM29957.1 - 0.00082 18.6 0.1 0.0011 18.2 0.1 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain SRP-alpha_N PF04086.13 EWM29957.1 - 0.0014 18.6 1.2 0.0018 18.3 1.2 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal Exo_endo_phos PF03372.23 EWM29958.1 - 4.4e-09 36.2 0.0 7.7e-05 22.3 0.0 2.5 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family GDP_Man_Dehyd PF16363.5 EWM29959.1 - 3.3e-07 30.0 0.0 3.7e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase zf-CCCH PF00642.24 EWM29960.1 - 0.0066 16.3 0.5 0.0066 16.3 0.5 2.2 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 EWM29960.1 - 0.046 14.2 1.2 0.046 14.2 1.2 2.8 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 EWM29960.1 - 0.64 10.2 13.5 3.4 7.9 2.4 3.6 3 1 0 3 3 3 0 Zinc finger domain GDP_Man_Dehyd PF16363.5 EWM29962.1 - 2.7e-25 89.5 0.1 3.5e-25 89.1 0.1 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EWM29962.1 - 1e-23 84.0 0.1 1.4e-23 83.7 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EWM29962.1 - 1.5e-08 34.3 0.1 2.2e-08 33.8 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.19 EWM29962.1 - 6.8e-08 31.9 0.0 8.8e-08 31.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EWM29962.1 - 7.4e-07 28.6 0.0 9.4e-07 28.2 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 EWM29962.1 - 5.3e-06 26.5 0.1 9.9e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 EWM29962.1 - 0.0004 19.6 0.0 0.00051 19.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short_C2 PF13561.6 EWM29962.1 - 0.0017 17.9 0.0 0.0021 17.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 EWM29962.1 - 0.0021 17.6 0.1 0.0029 17.2 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 EWM29962.1 - 0.0034 17.6 0.1 0.0051 17.1 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 EWM29962.1 - 0.0091 15.9 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EWM29962.1 - 0.012 15.2 0.1 0.016 14.8 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_10 PF13460.6 EWM29962.1 - 0.037 13.9 0.1 0.051 13.5 0.1 1.2 1 0 0 1 1 1 0 NAD(P)H-binding TrkA_N PF02254.18 EWM29962.1 - 0.073 13.3 0.1 0.2 11.9 0.1 1.8 2 0 0 2 2 2 0 TrkA-N domain ELFV_dehydrog PF00208.21 EWM29962.1 - 0.18 11.5 0.0 0.38 10.4 0.0 1.4 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Pkinase PF00069.25 EWM29965.1 - 3e-51 174.3 0.0 3.5e-51 174.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM29965.1 - 8.3e-29 100.6 0.0 9.5e-29 100.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EWM29965.1 - 0.0002 20.3 0.0 0.00028 19.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EWM29965.1 - 0.012 15.6 0.1 0.031 14.2 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EWM29965.1 - 0.012 14.9 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 EWM29965.1 - 0.047 13.0 0.4 0.79 9.0 0.0 2.5 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EWM29965.1 - 0.066 12.2 0.0 0.09 11.7 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 EWM29965.1 - 0.067 12.2 0.0 0.096 11.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Amino_oxidase PF01593.24 EWM29966.1 - 2e-55 188.9 0.0 2.6e-55 188.5 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EWM29966.1 - 2.7e-13 49.9 0.5 9.1e-13 48.2 0.5 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EWM29966.1 - 1.5e-05 24.8 1.7 0.001 18.7 1.9 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EWM29966.1 - 0.00018 22.0 0.2 0.33 11.5 0.6 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 EWM29966.1 - 0.00036 19.5 0.0 0.048 12.5 0.0 2.1 2 0 0 2 2 2 2 MCRA family FAD_binding_2 PF00890.24 EWM29966.1 - 0.00068 18.8 2.0 0.072 12.2 1.5 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EWM29966.1 - 0.00069 18.9 0.0 0.0082 15.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EWM29966.1 - 0.0017 17.2 0.6 0.011 14.5 0.8 2.2 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.19 EWM29966.1 - 0.013 14.8 0.4 0.02 14.1 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 EWM29966.1 - 0.014 14.7 0.3 0.027 13.8 0.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Rossmann-like PF10727.9 EWM29966.1 - 0.071 13.0 0.1 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 Rossmann-like domain DUF819 PF05684.12 EWM29967.1 - 3.8e-74 250.0 18.2 5e-74 249.6 18.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF819) TRAM_LAG1_CLN8 PF03798.16 EWM29968.1 - 4.3e-34 118.0 26.9 6e-34 117.5 26.9 1.2 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 EWM29968.1 - 0.00015 21.3 1.1 0.14 11.8 0.2 2.9 2 0 0 2 2 2 2 TRAM1-like protein RNase_T PF00929.24 EWM29970.1 - 3.7e-19 69.9 0.0 5.5e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 EWM29970.1 - 0.067 12.9 0.0 0.15 11.8 0.0 1.5 2 0 0 2 2 2 0 3'-5' exonuclease YCII PF03795.14 EWM29970.1 - 0.12 12.8 0.1 0.3 11.5 0.1 1.6 1 0 0 1 1 1 0 YCII-related domain UCH_1 PF13423.6 EWM29971.1 - 2.2e-06 27.5 0.0 3.2e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PQQ_3 PF13570.6 EWM29971.1 - 0.058 13.9 5.9 2.7 8.6 0.0 4.3 4 1 1 5 5 5 0 PQQ-like domain PK PF00224.21 EWM29972.1 - 1.8e-128 428.3 0.5 2.4e-128 427.9 0.5 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EWM29972.1 - 1.1e-19 70.8 0.1 3.3e-19 69.2 0.0 1.9 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EWM29972.1 - 0.00017 20.8 0.8 0.00067 18.8 0.3 2.0 1 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Glyco_hydro_3_C PF01915.22 EWM29972.1 - 0.013 15.4 0.1 0.017 15.1 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain VGPC1_C PF16799.5 EWM29972.1 - 0.12 12.4 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 C-terminal membrane-localisation domain of ion-channel, VCN1 DUF1961 PF09224.11 EWM29972.1 - 0.16 11.3 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1961) LEA_2 PF03168.13 EWM29974.1 - 0.03 14.9 0.0 0.075 13.6 0.0 1.7 1 1 0 1 1 1 0 Late embryogenesis abundant protein RhoGAP PF00620.27 EWM29975.1 - 9.5e-08 32.0 0.0 4.3e-05 23.4 0.0 3.0 2 1 0 2 2 2 2 RhoGAP domain Drc1-Sld2 PF11719.8 EWM29975.1 - 0.011 15.3 0.7 0.011 15.3 0.7 2.4 2 0 0 2 2 2 0 DNA replication and checkpoint protein His_Phos_1 PF00300.22 EWM29976.1 - 3.1e-10 40.1 0.0 4.4e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Glyco_hydro_9 PF00759.19 EWM29977.1 - 1.7e-118 396.7 2.6 2e-118 396.4 2.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 DUF4092 PF13322.6 EWM29977.1 - 0.077 12.9 0.1 0.46 10.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4092) Utp14 PF04615.13 EWM29978.1 - 2.3e-46 158.8 13.1 7.1e-46 157.2 13.1 1.6 1 1 0 1 1 1 1 Utp14 protein COPIIcoated_ERV PF07970.12 EWM29979.1 - 6e-62 209.4 0.0 8.6e-62 208.9 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EWM29979.1 - 9.8e-22 77.1 0.6 1.6e-21 76.4 0.6 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) SR-25 PF10500.9 EWM29981.1 - 2.6 7.6 4.9 4.3 6.9 4.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein UQ_con PF00179.26 EWM29983.1 - 2.5e-52 176.3 0.0 2.9e-52 176.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EWM29983.1 - 0.11 12.8 0.1 0.19 12.0 0.1 1.5 1 1 0 1 1 1 0 RWD domain DUF4611 PF15387.6 EWM29983.1 - 0.19 12.0 4.4 0.3 11.3 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Uso1_p115_C PF04871.13 EWM29983.1 - 1.7 9.1 10.6 2.5 8.5 10.6 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region NOA36 PF06524.12 EWM29983.1 - 3.6 6.8 7.5 4.5 6.5 7.5 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 EWM29983.1 - 8.9 4.3 7.2 11 3.9 7.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi UQ_con PF00179.26 EWM29984.1 - 3.8e-48 162.7 0.4 3.4e-47 159.6 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme DUF2570 PF10828.8 EWM29985.1 - 0.01 15.7 2.3 0.017 14.9 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Presenilin PF01080.17 EWM29985.1 - 0.83 8.4 2.3 0.78 8.4 2.3 1.1 1 0 0 1 1 1 0 Presenilin RapA_C PF12137.8 EWM29986.1 - 0.26 10.3 0.0 0.36 9.8 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal RapA_C PF12137.8 EWM29987.1 - 0.2 10.7 0.0 0.26 10.2 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal TPR_12 PF13424.6 EWM29988.1 - 4.8e-43 145.3 15.6 1.1e-16 60.8 1.0 6.1 4 2 1 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 EWM29988.1 - 1e-29 101.5 15.0 4.7e-07 29.5 0.1 7.4 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 EWM29988.1 - 2.7e-21 74.0 13.6 1.5e-05 24.6 0.4 8.4 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 EWM29988.1 - 1.3e-20 71.8 16.6 0.011 15.9 0.0 8.2 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 EWM29988.1 - 4.6e-18 64.2 17.0 0.00021 21.0 0.1 7.3 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 EWM29988.1 - 4.2e-16 57.7 20.4 0.00071 19.5 0.5 7.7 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 EWM29988.1 - 1.1e-08 35.6 17.0 0.0048 17.5 0.8 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 EWM29988.1 - 1.6e-07 31.6 19.5 0.085 13.7 0.8 7.8 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 EWM29988.1 - 2.9e-06 27.3 7.9 0.41 11.2 0.0 6.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EWM29988.1 - 1.5e-05 24.5 11.5 0.041 13.2 0.2 3.9 2 2 2 4 4 4 2 MalT-like TPR region RPN6_N PF18055.1 EWM29988.1 - 6.2e-05 23.3 0.2 1.5 9.2 0.0 4.0 2 1 1 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_19 PF14559.6 EWM29988.1 - 7.7e-05 23.1 20.0 1.1 9.8 1.3 6.5 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 EWM29988.1 - 0.00031 20.4 1.4 6.6 6.5 0.0 4.9 4 1 0 4 4 4 1 TPR repeat TPR_6 PF13174.6 EWM29988.1 - 0.0013 19.3 21.3 2 9.2 0.1 7.7 9 0 0 9 9 9 1 Tetratricopeptide repeat SPO22 PF08631.10 EWM29988.1 - 0.019 14.5 0.6 4.6 6.6 0.0 4.1 3 2 1 5 5 5 0 Meiosis protein SPO22/ZIP4 like ANAPC5 PF12862.7 EWM29988.1 - 0.091 12.8 1.3 8.3 6.6 0.0 3.5 4 1 1 5 5 4 0 Anaphase-promoting complex subunit 5 DUF2225 PF09986.9 EWM29988.1 - 0.16 11.6 1.2 13 5.5 0.2 3.0 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) Mad3_BUB1_I PF08311.12 EWM29988.1 - 0.25 11.3 1.9 2.5 8.1 0.1 3.0 4 0 0 4 4 3 0 Mad3/BUB1 homology region 1 CobT PF06213.12 EWM29988.1 - 0.84 9.0 10.3 0.66 9.3 1.4 2.8 2 1 1 3 3 3 0 Cobalamin biosynthesis protein CobT PLDc_N PF13396.6 EWM29989.1 - 1.7e-05 24.7 16.7 7.9e-05 22.5 16.7 1.9 1 1 0 1 1 1 1 Phospholipase_D-nuclease N-terminal DUF2788 PF10981.8 EWM29989.1 - 0.039 14.0 5.2 0.067 13.2 4.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2788) MARVEL PF01284.23 EWM29989.1 - 0.061 13.3 4.1 0.068 13.2 4.1 1.0 1 0 0 1 1 1 0 Membrane-associating domain LapA_dom PF06305.11 EWM29989.1 - 9.6 6.1 8.0 0.23 11.3 0.7 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Lipase_GDSL_2 PF13472.6 EWM29990.1 - 6.8e-06 26.6 0.1 1.1e-05 26.0 0.1 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EWM29990.1 - 0.001 19.1 0.0 0.021 14.8 0.0 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Hydrolase_6 PF13344.6 EWM29991.1 - 7.9e-15 54.8 0.0 1.3e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EWM29991.1 - 4.1e-11 42.8 0.0 8e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EWM29991.1 - 0.00099 19.4 0.0 0.12 12.6 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Diphthamide_syn PF01866.17 EWM29993.1 - 7.9e-111 370.3 0.0 9.2e-111 370.1 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein CRM1_C PF08767.11 EWM29994.1 - 0.00019 20.7 0.0 0.00042 19.6 0.0 1.5 2 0 0 2 2 2 1 CRM1 C terminal DUF3719 PF12516.8 EWM29994.1 - 0.18 11.5 0.0 0.43 10.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3719) Rhomboid PF01694.22 EWM29995.1 - 7.9e-19 68.1 4.0 7.9e-19 68.1 4.0 1.5 2 0 0 2 2 2 1 Rhomboid family DUF1751 PF08551.10 EWM29995.1 - 0.031 14.8 0.3 0.097 13.2 0.3 1.8 1 0 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) Kinesin PF00225.23 EWM29996.1 - 6.2e-83 278.5 0.0 3e-82 276.2 0.0 1.9 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EWM29996.1 - 1.4e-11 44.5 0.0 9.7e-11 41.8 0.0 2.1 1 1 0 1 1 1 1 Microtubule binding MIP PF00230.20 EWM29997.1 - 2.1e-20 73.4 10.9 3e-20 72.9 10.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein Ribosomal_L19e PF01280.20 EWM29998.1 - 1.2e-59 200.5 11.9 1.2e-59 200.5 11.9 1.8 2 0 0 2 2 2 1 Ribosomal protein L19e SH2_2 PF14633.6 EWM30000.1 - 5.1e-43 147.0 0.4 7.7e-43 146.4 0.4 1.2 1 0 0 1 1 1 1 SH2 domain SH2 PF00017.24 EWM30000.1 - 4.4e-06 26.7 0.0 1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 SH2 domain HHH_9 PF17674.1 EWM30000.1 - 1.6e-05 25.7 0.0 0.017 16.0 0.0 2.9 2 0 0 2 2 2 2 HHH domain S1 PF00575.23 EWM30000.1 - 0.0004 20.7 0.0 0.0011 19.3 0.0 1.8 1 0 0 1 1 1 1 S1 RNA binding domain ProQ_C PF17516.2 EWM30000.1 - 0.095 12.1 0.1 1.6 8.2 0.1 2.2 2 0 0 2 2 2 0 ProQ C-terminal domain DUF3493 PF11998.8 EWM30002.1 - 3e-19 68.9 0.0 6.3e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Low psii accumulation1 / Rep27 P53_TAD PF08563.11 EWM30002.1 - 0.04 13.4 0.4 0.49 9.9 0.0 2.5 2 0 0 2 2 2 0 P53 transactivation motif CAP_N PF01213.19 EWM30002.1 - 1.8 7.9 5.0 3.1 7.2 5.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal AAA PF00004.29 EWM30003.1 - 1.2e-91 304.0 0.0 7.9e-47 159.0 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EWM30003.1 - 1.1e-21 76.4 1.2 7.5e-12 44.9 0.1 2.8 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 EWM30003.1 - 3.2e-15 56.2 0.0 2.1e-07 30.8 0.0 2.7 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EWM30003.1 - 1.2e-11 45.3 1.0 0.0026 18.2 0.1 4.4 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 EWM30003.1 - 2.3e-10 40.9 1.4 0.022 15.0 0.0 4.3 4 2 1 5 5 4 2 AAA domain AAA_2 PF07724.14 EWM30003.1 - 2.7e-10 40.6 0.0 0.00021 21.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EWM30003.1 - 3e-10 40.4 0.0 0.00018 21.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EWM30003.1 - 1.1e-09 38.4 0.2 0.00095 19.2 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EWM30003.1 - 1.1e-08 34.7 0.0 0.00083 18.7 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain IstB_IS21 PF01695.17 EWM30003.1 - 6.1e-08 32.6 0.1 0.0075 16.0 0.1 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 EWM30003.1 - 2.2e-07 31.3 0.0 0.03 14.7 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.6 EWM30003.1 - 2.2e-07 31.5 0.0 0.022 15.3 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.6 EWM30003.1 - 3.3e-07 30.4 0.0 0.035 14.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EWM30003.1 - 4.8e-07 29.4 0.6 0.03 13.7 0.1 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EWM30003.1 - 5.9e-07 29.2 4.1 0.075 12.6 0.1 3.7 2 1 1 3 3 3 3 AAA domain AAA_28 PF13521.6 EWM30003.1 - 1.6e-06 28.4 0.0 0.082 13.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 EWM30003.1 - 1.9e-06 27.9 0.0 0.11 12.5 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 EWM30003.1 - 6.7e-06 26.1 0.0 0.15 12.0 0.0 2.3 2 0 0 2 2 2 2 Rad17 P-loop domain ABC_tran PF00005.27 EWM30003.1 - 7e-06 26.6 0.0 0.097 13.2 0.0 2.6 2 1 0 2 2 2 2 ABC transporter NACHT PF05729.12 EWM30003.1 - 1.3e-05 25.2 0.5 0.25 11.2 0.0 2.9 2 1 1 3 3 3 2 NACHT domain Zeta_toxin PF06414.12 EWM30003.1 - 3.1e-05 23.3 0.3 0.2 10.9 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin ATPase PF06745.13 EWM30003.1 - 3.8e-05 23.1 0.1 0.97 8.7 0.0 3.2 3 0 0 3 3 3 2 KaiC AAA_3 PF07726.11 EWM30003.1 - 5.2e-05 23.1 0.0 0.11 12.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 EWM30003.1 - 9.1e-05 22.9 0.1 0.54 10.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 EWM30003.1 - 0.00041 20.1 0.0 0.34 10.6 0.0 2.9 3 0 0 3 3 3 1 Sigma-54 interaction domain NB-ARC PF00931.22 EWM30003.1 - 0.00058 19.1 0.1 0.94 8.6 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain ATPase_2 PF01637.18 EWM30003.1 - 0.00075 19.5 0.0 1.8 8.4 0.0 3.2 2 2 1 3 3 3 1 ATPase domain predominantly from Archaea Cytidylate_kin2 PF13189.6 EWM30003.1 - 0.0009 19.4 0.0 0.1 12.7 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_7 PF12775.7 EWM30003.1 - 0.0011 18.6 0.0 0.99 8.9 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region Viral_helicase1 PF01443.18 EWM30003.1 - 0.0011 18.8 0.0 1.2 8.8 0.0 2.2 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Parvo_NS1 PF01057.17 EWM30003.1 - 0.002 17.2 0.1 0.3 10.1 0.0 2.1 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 PhoH PF02562.16 EWM30003.1 - 0.0023 17.4 0.6 1.3 8.4 0.1 2.4 2 0 0 2 2 2 1 PhoH-like protein Sigma54_activ_2 PF14532.6 EWM30003.1 - 0.0041 17.2 0.0 0.48 10.5 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_24 PF13479.6 EWM30003.1 - 0.0045 16.7 0.0 2.2 8.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain Hydin_ADK PF17213.3 EWM30003.1 - 0.0069 16.7 0.1 0.4 10.9 0.0 2.5 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain SKI PF01202.22 EWM30003.1 - 0.017 15.3 0.0 5.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase AAA_11 PF13086.6 EWM30003.1 - 0.017 14.9 0.0 2.4 7.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EWM30003.1 - 0.017 14.8 0.0 3.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF2075 PF09848.9 EWM30003.1 - 0.03 13.6 0.0 2.4 7.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.13 EWM30003.1 - 0.036 13.2 0.0 3.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) CPT PF07931.12 EWM30003.1 - 0.039 13.8 0.0 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Cytidylate_kin PF02224.18 EWM30003.1 - 0.039 13.7 0.2 5.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase NTPase_1 PF03266.15 EWM30003.1 - 0.047 13.6 0.1 9.4 6.1 0.0 2.6 2 1 0 2 2 2 0 NTPase ATP-synt_ab PF00006.25 EWM30003.1 - 0.064 12.9 0.0 2.2 7.9 0.0 2.6 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain Zot PF05707.12 EWM30003.1 - 0.068 12.8 0.0 0.64 9.6 0.0 2.5 3 1 0 3 3 1 0 Zonular occludens toxin (Zot) AAA_23 PF13476.6 EWM30003.1 - 0.24 11.9 0.0 29 5.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 EWM30003.1 - 0.27 10.8 0.2 10 5.6 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Bac_DnaA PF00308.18 EWM30003.1 - 0.28 11.0 0.1 16 5.3 0.0 2.5 2 1 0 2 2 2 0 Bacterial dnaA protein AAA_19 PF13245.6 EWM30003.1 - 0.28 11.5 5.1 14 6.0 0.1 3.3 3 1 0 3 3 3 0 AAA domain DNA_binding_1 PF01035.20 EWM30004.1 - 5.9e-22 77.6 0.1 1.1e-21 76.7 0.1 1.5 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain IstB_IS21 PF01695.17 EWM30004.1 - 0.094 12.4 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein HHH_7 PF14635.6 EWM30006.1 - 3.2e-15 56.4 0.0 1.2e-14 54.5 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif HTH_44 PF14641.6 EWM30006.1 - 2e-13 50.8 0.4 4.4e-13 49.7 0.4 1.5 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 YqgF PF14639.6 EWM30006.1 - 4.7e-13 49.2 0.0 1.5e-12 47.5 0.0 1.9 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 Tex_N PF09371.10 EWM30006.1 - 6.2e-05 22.8 0.5 0.07 12.8 0.0 4.0 3 1 0 3 3 3 1 Tex-like protein N-terminal domain Tex_YqgF PF16921.5 EWM30006.1 - 0.0011 19.4 0.0 0.0026 18.2 0.0 1.7 1 0 0 1 1 1 1 Tex protein YqgF-like domain V_ATPase_I PF01496.19 EWM30006.1 - 2.5 5.9 5.3 4.6 5.0 5.3 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TPR_1 PF00515.28 EWM30007.1 - 3.4e-19 67.8 10.6 1.7e-06 27.6 0.0 5.7 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 EWM30007.1 - 7.9e-18 63.1 10.1 1.2e-05 25.1 0.0 5.7 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 EWM30007.1 - 8.9e-15 54.1 8.7 0.0001 21.9 0.0 4.8 2 2 3 5 5 5 4 TPR repeat TPR_8 PF13181.6 EWM30007.1 - 9.1e-13 47.3 7.6 0.0006 19.8 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 EWM30007.1 - 1.4e-11 43.9 8.9 0.00033 20.8 0.1 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 EWM30007.1 - 2.1e-10 40.9 8.8 2.3e-06 28.0 0.3 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 EWM30007.1 - 7.5e-10 38.1 5.5 0.19 11.8 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EWM30007.1 - 2e-09 37.5 5.9 0.18 12.7 0.0 4.9 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 EWM30007.1 - 3e-09 37.0 14.8 0.00018 21.7 2.2 4.5 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.6 EWM30007.1 - 1.1e-08 35.5 6.7 0.0018 18.9 1.2 3.5 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_15 PF13429.6 EWM30007.1 - 5.4e-06 25.8 3.4 0.033 13.4 0.1 3.6 2 2 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 EWM30007.1 - 5.6e-06 26.4 1.2 0.024 14.8 0.1 3.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 EWM30007.1 - 3.3e-05 24.2 11.4 0.08 13.6 0.0 5.7 5 1 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EWM30007.1 - 0.00092 19.4 5.2 0.08 13.2 0.0 2.3 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EWM30007.1 - 0.002 17.9 11.8 2.8 7.9 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat Glyco_hyd_65N_2 PF14498.6 EWM30007.1 - 0.016 15.1 0.0 0.22 11.3 0.0 2.2 1 1 1 2 2 2 0 Glycosyl hydrolase family 65, N-terminal domain TPR_20 PF14561.6 EWM30007.1 - 0.026 14.9 1.2 0.77 10.1 0.1 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat ChAPs PF09295.10 EWM30007.1 - 0.23 10.4 0.4 2.2 7.2 0.1 1.9 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) ATP_bind_3 PF01171.20 EWM30009.1 - 2.7e-05 24.0 0.0 2.7e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 PP-loop family FoP_duplication PF13865.6 EWM30010.1 - 0.044 14.3 5.5 0.061 13.9 5.5 1.2 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 TPX2 PF06886.11 EWM30011.1 - 5.1 7.4 12.6 9.6 6.5 12.6 1.4 1 1 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) PSK_trans_fac PF07704.11 EWM30013.1 - 0.02 15.7 1.2 0.03 15.1 0.7 1.7 1 1 0 1 1 1 0 Rv0623-like transcription factor Maf_N PF08383.11 EWM30013.1 - 0.054 13.3 0.3 0.19 11.6 0.1 2.1 2 0 0 2 2 2 0 Maf N-terminal region TetR_C_32 PF09209.11 EWM30013.1 - 0.09 12.8 0.5 1.2 9.2 0.5 2.3 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain IMUP PF15761.5 EWM30014.1 - 0.25 12.0 7.1 0.51 11.1 7.1 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 EWM30014.1 - 0.52 9.9 9.6 0.87 9.2 9.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 EWM30014.1 - 5.6 7.3 10.2 9.3 6.5 10.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DnaJ PF00226.31 EWM30015.1 - 3.4e-14 52.7 0.0 7e-14 51.7 0.0 1.5 1 1 0 1 1 1 1 DnaJ domain zf-CSL PF05207.13 EWM30015.1 - 1e-11 44.3 0.6 5.4e-11 42.1 0.6 2.0 1 1 0 1 1 1 1 CSL zinc finger Phage_fiber_2 PF03406.13 EWM30015.1 - 0.066 12.8 0.7 0.066 12.8 0.7 1.7 2 0 0 2 2 2 0 Phage tail fibre repeat PrmC_N PF17827.1 EWM30016.1 - 3e-11 43.8 0.0 5.8e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 PrmC N-terminal domain MTS PF05175.14 EWM30016.1 - 3.2e-06 26.8 0.0 0.0025 17.4 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_31 PF13847.6 EWM30016.1 - 3.9e-06 26.7 0.0 5.8e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM30016.1 - 0.00016 22.3 0.0 0.00073 20.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EWM30016.1 - 0.0015 18.4 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EWM30016.1 - 0.0024 18.6 0.0 0.0051 17.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM30016.1 - 0.014 16.0 0.0 0.036 14.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 EWM30016.1 - 0.027 14.1 0.0 2.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical protein 95 PrmA PF06325.13 EWM30016.1 - 0.11 11.9 0.0 0.24 10.7 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Eco57I PF07669.11 EWM30016.1 - 0.23 12.0 0.0 0.37 11.3 0.0 1.3 1 0 0 1 1 1 0 Eco57I restriction-modification methylase WD40 PF00400.32 EWM30017.1 - 4.9e-15 55.7 7.9 0.00042 21.1 0.0 6.7 5 1 0 5 5 5 3 WD domain, G-beta repeat zf-CCCH_4 PF18044.1 EWM30017.1 - 0.002 17.9 1.7 0.0045 16.8 1.7 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger Nup160 PF11715.8 EWM30017.1 - 0.0039 15.9 0.0 0.15 10.6 0.0 2.6 2 1 1 3 3 3 1 Nucleoporin Nup120/160 PQQ_2 PF13360.6 EWM30017.1 - 0.013 15.1 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 PQQ-like domain Nucleoporin_N PF08801.11 EWM30017.1 - 0.25 10.0 0.0 18 3.9 0.0 3.2 4 1 1 5 5 5 0 Nup133 N terminal like Peptidase_S41 PF03572.18 EWM30018.1 - 6.9e-48 162.4 0.0 1e-47 161.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S41 PDZ PF00595.24 EWM30018.1 - 1.1e-06 28.9 0.0 5.1e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EWM30018.1 - 0.00014 21.6 0.1 0.00027 20.7 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EWM30018.1 - 0.002 18.4 0.1 0.0046 17.2 0.1 1.5 1 0 0 1 1 1 1 PDZ domain Tricorn_C1 PF14684.6 EWM30018.1 - 0.01 15.9 0.1 0.019 15.0 0.1 1.4 1 0 0 1 1 1 0 Tricorn protease C1 domain Polyketide_cyc2 PF10604.9 EWM30018.1 - 0.031 14.6 0.0 0.087 13.1 0.0 1.8 2 0 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport Fapy_DNA_glyco PF01149.24 EWM30020.1 - 9.1e-25 87.5 1.2 2.6e-24 86.1 0.1 2.2 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 EWM30020.1 - 7e-18 64.4 0.0 1.2e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Ribosomal_S13 PF00416.22 EWM30020.1 - 0.0049 17.3 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DUF639 PF04842.12 EWM30021.1 - 0.035 13.5 0.2 0.056 12.8 0.1 1.3 1 1 0 1 1 1 0 Plant protein of unknown function (DUF639) SNARE_assoc PF09335.11 EWM30022.1 - 3e-11 43.8 1.6 3.6e-11 43.6 0.5 1.6 2 0 0 2 2 2 1 SNARE associated Golgi protein SfLAP PF11139.8 EWM30022.1 - 0.0078 15.7 0.5 0.011 15.1 0.5 1.2 1 0 0 1 1 1 1 Sap, sulfolipid-1-addressing protein DUF4920 PF16267.5 EWM30024.1 - 0.036 14.0 0.0 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4920) Cation_ATPase_N PF00690.26 EWM30025.1 - 2.9e-09 36.5 0.0 6e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus E1-E2_ATPase PF00122.20 EWM30025.1 - 0.014 14.9 0.1 0.035 13.6 0.1 1.7 1 0 0 1 1 1 0 E1-E2 ATPase UPF0547 PF10571.9 EWM30026.1 - 0.074 13.1 1.3 0.12 12.5 1.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 CpXC PF14353.6 EWM30026.1 - 0.14 12.2 0.1 4.7 7.3 0.0 2.3 2 0 0 2 2 2 0 CpXC protein UPF0547 PF10571.9 EWM30027.1 - 0.074 13.1 1.3 0.12 12.5 1.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 CpXC PF14353.6 EWM30027.1 - 0.14 12.2 0.1 4.7 7.3 0.0 2.3 2 0 0 2 2 2 0 CpXC protein DUF5454 PF17535.2 EWM30028.1 - 0.026 13.9 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5454) C_Hendra PF16821.5 EWM30031.1 - 0.054 13.4 0.1 0.098 12.5 0.1 1.3 1 0 0 1 1 1 0 C protein from hendra and measles viruses Cation_ATPase_C PF00689.21 EWM30032.1 - 1.3e-11 44.5 0.0 1.8e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Lipase_3 PF01764.25 EWM30033.1 - 7.8e-32 110.1 0.0 1.2e-31 109.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 EWM30033.1 - 0.00033 20.0 0.0 0.00065 19.0 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EWM30033.1 - 0.0055 16.8 0.0 0.0093 16.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain DUF2974 PF11187.8 EWM30033.1 - 0.029 13.9 0.1 2 7.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 EWM30033.1 - 0.051 14.2 3.9 0.07 13.7 3.2 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.20 EWM30033.1 - 0.11 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase CEBP_ZZ PF16366.5 EWM30033.1 - 1.2 9.4 6.0 0.17 12.2 1.6 1.8 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Peptidase_S10 PF00450.22 EWM30035.1 - 6.7e-108 361.8 0.2 8.9e-108 361.4 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Hydrolase_4 PF12146.8 EWM30035.1 - 0.00018 20.9 0.0 0.0022 17.3 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 NPL4 PF05021.15 EWM30037.1 - 2.6e-05 23.7 0.1 0.19 11.0 0.0 2.1 2 0 0 2 2 2 2 NPL4 family Peptidase_S10 PF00450.22 EWM30038.1 - 1e-120 404.0 0.2 1.2e-120 403.7 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Hydrolase_4 PF12146.8 EWM30038.1 - 0.03 13.6 0.0 0.24 10.7 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 HNH PF01844.23 EWM30039.1 - 1.4e-06 28.3 0.5 3.4e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 HNH endonuclease HNH_5 PF14279.6 EWM30039.1 - 0.0049 16.7 0.6 0.02 14.7 0.0 2.2 2 0 0 2 2 2 1 HNH endonuclease SAP PF02037.27 EWM30039.1 - 0.0057 16.4 0.0 0.02 14.6 0.0 2.0 2 0 0 2 2 2 1 SAP domain DUF4460 PF14687.6 EWM30040.1 - 9.3e-14 51.4 0.7 1.9e-13 50.4 0.7 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4460) YopE_N PF09020.10 EWM30040.1 - 8.6 6.6 8.4 0.35 11.1 1.7 2.1 2 1 0 2 2 2 0 YopE, N terminal Ank_2 PF12796.7 EWM30041.1 - 1.1e-17 64.4 0.0 1.2e-06 29.0 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EWM30041.1 - 1.3e-14 54.0 2.5 1.8e-05 24.9 0.0 4.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EWM30041.1 - 3.9e-14 51.4 3.1 4e-05 23.7 0.0 5.3 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 EWM30041.1 - 1.8e-13 50.7 0.8 1.5e-05 25.4 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EWM30041.1 - 1.2e-10 41.4 0.3 0.00065 20.0 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Peptidase_M16_M PF16187.5 EWM30042.1 - 2e-73 247.1 0.5 3e-73 246.5 0.5 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 EWM30042.1 - 9.8e-31 107.2 0.0 5e-20 72.3 0.0 3.6 4 1 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EWM30042.1 - 1e-09 38.5 0.1 2.9e-09 37.0 0.1 1.9 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_M PF16187.5 EWM30043.1 - 1e-73 248.1 0.5 1.5e-73 247.6 0.5 1.2 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 EWM30043.1 - 1.4e-22 80.6 0.0 2.8e-20 73.1 0.0 3.1 3 1 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EWM30043.1 - 8e-10 38.9 0.1 1.9e-09 37.6 0.1 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Maf PF02545.14 EWM30044.1 - 6.8e-53 178.9 0.0 8e-53 178.7 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein GMC_oxred_N PF00732.19 EWM30046.1 - 9.8e-47 159.7 0.0 4.8e-45 154.2 0.0 2.6 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EWM30046.1 - 2.7e-23 83.1 0.0 5e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 EWM30046.1 - 2e-07 31.0 0.3 8.4e-07 28.9 0.3 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EWM30046.1 - 0.00026 21.1 0.0 0.00069 19.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EWM30046.1 - 0.0037 16.4 0.1 0.0067 15.5 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EWM30046.1 - 0.012 14.7 0.8 0.049 12.7 0.2 2.0 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 EWM30046.1 - 0.021 14.1 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 EWM30046.1 - 0.033 13.4 0.0 0.22 10.7 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DapB_C PF05173.14 EWM30047.1 - 5.1e-17 62.0 0.0 7.9e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus DapB_N PF01113.20 EWM30047.1 - 6.3e-11 42.5 0.2 2.1e-10 40.8 0.2 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DapB_N PF01113.20 EWM30048.1 - 4.2e-11 43.0 0.3 1.2e-10 41.5 0.3 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus HSP90 PF00183.18 EWM30050.1 - 1.3e-107 360.9 0.1 9.2e-102 341.6 0.0 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 EWM30050.1 - 3.4e-09 36.6 0.1 9.6e-09 35.2 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EWM30050.1 - 2e-07 31.5 0.1 4.6e-07 30.3 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PRESAN PF09687.10 EWM30050.1 - 0.81 10.3 3.3 25 5.4 0.2 2.5 2 0 0 2 2 2 0 Plasmodium RESA N-terminal NTR PF01759.21 EWM30051.1 - 0.015 15.1 0.3 0.056 13.2 0.1 2.0 2 0 0 2 2 2 0 UNC-6/NTR/C345C module DTHCT PF08070.11 EWM30051.1 - 7.7 7.3 6.8 14 6.4 0.1 2.9 2 1 0 2 2 2 0 DTHCT (NUC029) region RNase_PH PF01138.21 EWM30053.1 - 1.4e-29 103.2 0.0 3.6e-29 101.9 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EWM30053.1 - 8.1e-05 22.6 0.0 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 PUNUT PF16913.5 EWM30054.1 - 0.00044 19.6 0.1 0.00077 18.8 0.1 1.3 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport Nuc_sug_transp PF04142.15 EWM30054.1 - 0.00058 19.1 1.3 0.00093 18.4 1.3 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter SLC35F PF06027.12 EWM30054.1 - 0.0056 16.2 3.7 0.01 15.4 3.7 1.3 1 0 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 EWM30054.1 - 0.028 14.6 0.9 0.028 14.6 0.9 3.3 2 1 0 2 2 2 0 EamA-like transporter family TPT PF03151.16 EWM30054.1 - 0.051 12.9 7.0 0.081 12.3 7.0 1.3 1 1 0 1 1 1 0 Triose-phosphate Transporter family UbiA PF01040.18 EWM30055.1 - 4.9e-34 117.8 13.7 4.9e-34 117.8 13.7 1.7 2 0 0 2 2 2 1 UbiA prenyltransferase family Retrotran_gag_2 PF14223.6 EWM30056.1 - 4.3e-08 32.9 0.4 6.7e-08 32.3 0.4 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF1759 PF03564.15 EWM30056.1 - 0.0037 17.2 1.5 0.0085 16.0 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) SF1-HH PF16275.5 EWM30057.1 - 5.7e-28 97.5 0.5 1.4e-27 96.2 0.5 1.7 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 EWM30057.1 - 1.3e-07 31.4 2.6 4.6e-07 29.6 2.6 1.9 1 1 0 1 1 1 1 KH domain PHD_4 PF16866.5 EWM30057.1 - 0.0014 18.7 2.2 0.004 17.2 2.2 1.8 1 0 0 1 1 1 1 PHD-finger zf-CCHC PF00098.23 EWM30057.1 - 0.0073 16.4 2.3 0.0073 16.4 2.3 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.6 EWM30057.1 - 0.96 9.5 7.4 2 8.4 5.3 2.4 1 1 1 2 2 2 0 Zinc knuckle Mito_carr PF00153.27 EWM30058.1 - 1.6e-37 127.3 3.8 8.3e-14 51.3 0.2 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Cation_ATPase_C PF00689.21 EWM30060.1 - 0.029 14.1 4.0 0.055 13.2 4.0 1.4 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus PMP22_Claudin PF00822.20 EWM30061.1 - 0.0038 17.1 7.9 0.011 15.7 6.0 1.9 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin family DUF2569 PF10754.9 EWM30061.1 - 0.02 15.3 11.3 0.088 13.2 3.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) DUF2070 PF09843.9 EWM30061.1 - 0.029 12.7 10.7 0.035 12.4 10.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) SURF4 PF02077.15 EWM30061.1 - 0.045 13.3 1.0 0.045 13.3 1.0 1.9 1 1 1 2 2 2 0 SURF4 family DPM3 PF08285.11 EWM30061.1 - 4.3 7.6 10.5 1.1 9.5 0.4 2.3 1 1 1 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DHHC PF01529.20 EWM30061.1 - 9.4 6.3 10.7 1.9e+03 -1.2 10.7 2.1 1 1 0 1 1 1 0 DHHC palmitoyltransferase DUF4149 PF13664.6 EWM30063.1 - 3e-25 88.5 2.2 3e-25 88.5 2.2 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4149) DUF2620 PF10941.8 EWM30063.1 - 0.029 14.5 0.1 0.044 13.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF2620 LIDHydrolase PF10230.9 EWM30064.1 - 6.5e-07 29.2 0.0 6.2e-06 26.0 0.0 2.2 1 1 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 EWM30064.1 - 1.2e-06 29.3 6.0 1.7e-06 28.8 6.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EWM30064.1 - 0.061 12.9 0.0 0.094 12.3 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EWM30064.1 - 0.088 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 EWM30064.1 - 0.14 11.8 0.1 0.23 11.1 0.1 1.5 1 1 0 1 1 1 0 PGAP1-like protein ROK PF00480.20 EWM30065.1 - 2.2e-31 109.5 0.2 5.4e-22 78.6 1.3 2.0 2 0 0 2 2 2 2 ROK family TPP_enzyme_N PF02776.18 EWM30065.1 - 0.16 11.5 0.1 0.28 10.8 0.1 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Synaptobrevin PF00957.21 EWM30066.1 - 7.9e-28 96.1 0.2 1.1e-27 95.6 0.2 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EWM30066.1 - 2.5e-18 65.9 0.0 4.1e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Acetyltransf_1 PF00583.25 EWM30067.1 - 5.2e-11 42.8 0.0 9.1e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EWM30067.1 - 9.5e-10 38.8 0.0 1.6e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EWM30067.1 - 4e-08 33.2 0.0 6.6e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EWM30067.1 - 7.5e-06 25.8 0.0 3.1e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_15 PF17013.5 EWM30067.1 - 0.0053 16.2 0.0 0.0083 15.6 0.0 1.2 1 0 0 1 1 1 1 Putative acetyl-transferase AIG2_2 PF13772.6 EWM30067.1 - 0.15 12.5 0.1 0.28 11.6 0.1 1.4 1 0 0 1 1 1 0 AIG2-like family Acetyltransf_9 PF13527.7 EWM30067.1 - 0.19 11.8 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Kinetochor_Ybp2 PF08568.10 EWM30068.1 - 1e-07 30.9 0.0 2e-06 26.6 0.0 2.2 2 1 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin Elf1 PF05129.13 EWM30069.1 - 0.095 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like FAM117 PF15388.6 EWM30070.1 - 0.022 14.2 0.4 0.022 14.2 0.4 1.1 1 0 0 1 1 1 0 Protein Family FAM117 Chloroa_b-bind PF00504.21 EWM30071.1 - 5.3e-32 111.6 0.0 7.7e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Myb_DNA-binding PF00249.31 EWM30072.1 - 9e-25 86.6 4.5 5.5e-12 45.7 0.0 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EWM30072.1 - 1.1e-24 86.4 3.5 2.6e-16 59.6 0.3 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 EWM30072.1 - 2.8e-05 24.1 0.2 0.29 11.2 0.0 2.1 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 EWM30072.1 - 0.00013 21.8 1.8 0.031 14.2 0.2 2.1 1 1 1 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 EWM30072.1 - 0.00077 19.6 0.9 0.075 13.2 0.3 2.8 2 1 0 2 2 2 1 Rap1 Myb domain SLIDE PF09111.10 EWM30072.1 - 0.002 18.1 0.2 1.5 8.8 0.2 2.4 1 1 1 2 2 2 2 SLIDE Glutaredoxin2_C PF04399.13 EWM30073.1 - 0.17 11.7 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Amidohydro_1 PF01979.20 EWM30074.1 - 1.1e-66 225.5 2.5 8.1e-51 173.4 1.4 2.2 2 0 0 2 2 2 2 Amidohydrolase family Urease_alpha PF00449.20 EWM30074.1 - 1.3e-47 161.0 0.5 2.7e-47 160.0 0.5 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.18 EWM30074.1 - 1e-40 138.0 0.0 2.8e-40 136.6 0.0 1.8 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.20 EWM30074.1 - 3.1e-38 129.8 0.0 4e-37 126.2 0.0 2.4 2 0 0 2 2 2 1 Urease beta subunit Amidohydro_3 PF07969.11 EWM30074.1 - 4.4e-11 42.9 0.5 5.8e-07 29.3 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Y2_Tnp PF04986.13 EWM30074.1 - 0.21 11.7 0.0 0.39 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative transposase MFS_1 PF07690.16 EWM30075.1 - 1.1e-11 44.3 10.4 1.5e-11 43.9 10.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EWM30075.1 - 0.003 16.5 7.8 0.003 16.5 7.8 1.9 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 EWM30076.1 - 1.1e-11 44.3 10.4 1.5e-11 43.9 10.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EWM30076.1 - 0.003 16.5 7.8 0.003 16.5 7.8 1.9 2 1 0 2 2 2 1 Sugar (and other) transporter TauD PF02668.16 EWM30077.1 - 2.4e-58 198.1 0.0 2.9e-58 197.8 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 EWM30078.1 - 3.6e-21 75.5 5.1 4.9e-21 75.0 5.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 EWM30078.1 - 0.0066 15.1 7.6 0.098 11.2 6.9 2.1 1 1 1 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.13 EWM30078.1 - 0.023 13.1 2.1 0.033 12.6 2.1 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Dsh_C PF12316.8 EWM30078.1 - 0.052 13.9 9.5 0.078 13.4 9.5 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal CDC45 PF02724.14 EWM30078.1 - 0.24 9.7 8.8 0.33 9.2 8.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF443 PF04276.12 EWM30078.1 - 0.84 9.4 6.5 0.05 13.4 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Nop14 PF04147.12 EWM30078.1 - 1.2 7.3 13.1 1.5 6.9 13.1 1.0 1 0 0 1 1 1 0 Nop14-like family CCSAP PF15748.5 EWM30078.1 - 9.8 6.3 15.4 13 5.8 15.4 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated RR_TM4-6 PF06459.12 EWM30078.1 - 9.9 5.9 13.7 15 5.3 13.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MFS_1 PF07690.16 EWM30079.1 - 4.6e-21 75.1 5.2 6.2e-21 74.7 5.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 EWM30079.1 - 0.0051 15.4 7.7 0.071 11.7 6.9 2.1 1 1 1 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.13 EWM30079.1 - 0.019 13.4 2.2 0.026 12.9 2.2 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Dsh_C PF12316.8 EWM30079.1 - 0.053 13.9 9.5 0.078 13.4 9.5 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal CDC45 PF02724.14 EWM30079.1 - 0.24 9.7 8.8 0.33 9.2 8.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EWM30079.1 - 1.2 7.3 13.1 1.5 6.9 13.1 1.0 1 0 0 1 1 1 0 Nop14-like family DUF443 PF04276.12 EWM30079.1 - 1.3 8.8 6.8 0.068 13.0 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF443) CCSAP PF15748.5 EWM30079.1 - 9.8 6.3 15.4 13 5.8 15.4 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated RR_TM4-6 PF06459.12 EWM30079.1 - 9.9 5.9 13.7 15 5.3 13.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SMI1_KNR4 PF09346.10 EWM30080.1 - 3.7e-08 33.9 0.0 1.1e-07 32.3 0.0 1.8 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Nop14 PF04147.12 EWM30082.1 - 0.12 10.5 36.2 0.14 10.3 36.2 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2722 PF10846.8 EWM30082.1 - 0.29 10.0 4.7 0.33 9.8 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) V_ATPase_I PF01496.19 EWM30082.1 - 1.4 6.7 6.8 1.6 6.5 6.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mpp10 PF04006.12 EWM30082.1 - 2.7 6.3 35.3 3.6 5.9 35.3 1.1 1 0 0 1 1 1 0 Mpp10 protein TFIIA PF03153.13 EWM30082.1 - 2.8 7.8 22.1 3.4 7.6 22.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RNA_pol_Rpc4 PF05132.14 EWM30082.1 - 3.9 7.9 10.9 8.8 6.8 10.9 1.6 1 1 0 1 1 1 0 RNA polymerase III RPC4 BAF1_ABF1 PF04684.13 EWM30084.1 - 0.067 12.2 17.9 0.084 11.9 17.9 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SAPS PF04499.15 EWM30084.1 - 0.07 11.9 13.1 0.084 11.6 13.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GREB1 PF15782.5 EWM30084.1 - 0.16 9.1 23.5 0.19 8.8 23.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MMR1 PF08505.10 EWM30084.1 - 0.17 12.2 28.7 0.41 10.9 27.5 2.2 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein DUF4551 PF15087.6 EWM30084.1 - 0.24 10.2 17.1 0.4 9.5 17.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF4407 PF14362.6 EWM30084.1 - 0.32 10.3 20.7 0.43 9.9 20.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RR_TM4-6 PF06459.12 EWM30084.1 - 0.57 10.0 30.6 0.83 9.4 30.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Exonuc_VII_L PF02601.15 EWM30084.1 - 0.59 9.7 18.8 0.74 9.3 18.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit eIF-3_zeta PF05091.12 EWM30084.1 - 0.63 9.0 29.3 0.96 8.4 29.3 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Hid1 PF12722.7 EWM30084.1 - 0.78 7.8 27.7 1 7.4 27.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SID-1_RNA_chan PF13965.6 EWM30084.1 - 1 7.7 8.8 1.3 7.4 8.8 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SLC12 PF03522.15 EWM30084.1 - 1.1 8.2 26.0 1.4 7.9 26.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CDC45 PF02724.14 EWM30084.1 - 1.3 7.3 22.3 1.6 6.9 22.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 EWM30084.1 - 1.4 7.6 33.2 1.9 7.2 33.2 1.1 1 0 0 1 1 1 0 Presenilin BORG_CEP PF14957.6 EWM30084.1 - 1.4 10.1 20.7 0.32 12.1 16.9 2.0 2 0 0 2 2 1 0 Cdc42 effector DUF913 PF06025.12 EWM30084.1 - 1.7 7.6 14.2 2.3 7.1 14.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Peptidase_S64 PF08192.11 EWM30084.1 - 1.8 7.0 20.8 2.3 6.6 20.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 PA26 PF04636.13 EWM30084.1 - 1.9 7.3 18.0 2.6 6.9 18.0 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SprA-related PF12118.8 EWM30084.1 - 2.2 7.3 41.3 4 6.5 41.3 1.5 1 0 0 1 1 1 0 SprA-related family SRP-alpha_N PF04086.13 EWM30084.1 - 2.4 8.0 23.6 3.8 7.3 23.6 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal NST1 PF13945.6 EWM30084.1 - 2.4 8.2 34.6 3.9 7.5 34.6 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Neur_chan_memb PF02932.16 EWM30084.1 - 3.1 7.8 20.3 5.9 6.9 20.3 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM60A PF15396.6 EWM30084.1 - 3.4 7.6 19.4 5.1 7.1 19.4 1.2 1 0 0 1 1 1 0 Protein Family FAM60A PDDEXK_6 PF04720.12 EWM30084.1 - 3.7 7.4 14.9 5.4 6.9 14.9 1.2 1 0 0 1 1 1 0 PDDEXK-like family of unknown function CCSAP PF15748.5 EWM30084.1 - 4.2 7.5 36.9 0.16 12.1 31.2 1.5 2 0 0 2 2 1 0 Centriole, cilia and spindle-associated SpoIIP PF07454.11 EWM30084.1 - 5.3 6.4 26.6 8.6 5.7 26.6 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) HABP4_PAI-RBP1 PF04774.15 EWM30084.1 - 5.9 7.8 26.3 9.7 7.1 26.3 1.3 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family CPSF100_C PF13299.6 EWM30084.1 - 8.6 6.5 20.3 16 5.6 20.3 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Ndc1_Nup PF09531.10 EWM30084.1 - 8.6 4.9 26.8 13 4.4 26.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ABC2_membrane_2 PF12679.7 EWM30084.1 - 8.8 5.5 6.7 16 4.7 6.7 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein Tim54 PF11711.8 EWM30084.1 - 9.3 4.9 26.3 13 4.5 26.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 AUX_IAA PF02309.16 EWM30084.1 - 9.7 6.0 16.7 14 5.5 16.7 1.2 1 0 0 1 1 1 0 AUX/IAA family Pyridoxal_deC PF00282.19 EWM30087.1 - 4.1e-39 134.3 0.0 5.7e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Pyr_redox_2 PF07992.14 EWM30088.1 - 2.1e-23 83.0 0.0 2.6e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EWM30088.1 - 0.00046 20.7 0.0 0.0015 19.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EWM30088.1 - 0.0072 16.5 0.7 0.015 15.6 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Glucodextran_B PF09136.10 EWM30088.1 - 0.034 14.5 0.1 0.07 13.5 0.0 1.5 2 0 0 2 2 2 0 Glucodextranase, domain B Lycopene_cycl PF05834.12 EWM30088.1 - 0.13 11.3 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 EWM30088.1 - 0.23 10.5 0.0 4.3 6.3 0.0 2.0 1 1 1 2 2 2 0 Glucose inhibited division protein A Pyridoxal_deC PF00282.19 EWM30089.1 - 9.5e-13 47.6 0.0 1.2e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Pyr_redox_2 PF07992.14 EWM30090.1 - 1.4e-18 67.2 0.0 1.6e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EWM30090.1 - 3.9e-06 27.3 0.0 8e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SAS-6_N PF16531.5 EWM30093.1 - 1.8e-17 63.7 0.0 4.5e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal ATG16 PF08614.11 EWM30093.1 - 0.0034 17.6 46.4 0.026 14.8 22.9 3.6 2 1 1 3 3 3 2 Autophagy protein 16 (ATG16) Nup88 PF10168.9 EWM30093.1 - 0.48 8.2 19.6 0.98 7.2 19.6 1.5 1 1 0 1 1 1 0 Nuclear pore component Dynamin_N PF00350.23 EWM30094.1 - 2.1e-22 79.9 0.0 1.5e-10 41.4 0.0 2.7 1 1 1 2 2 2 2 Dynamin family MMR_HSR1 PF01926.23 EWM30094.1 - 1.9e-11 44.1 0.0 7.1e-11 42.2 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EWM30094.1 - 8.9e-06 25.4 0.0 5.2e-05 22.9 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EWM30094.1 - 2.1e-05 24.5 0.2 0.049 13.5 0.1 2.9 1 1 1 2 2 2 2 RsgA GTPase Ras PF00071.22 EWM30094.1 - 0.0035 17.0 0.0 0.068 12.8 0.0 2.5 1 1 1 2 2 2 1 Ras family Spore_IV_A PF09547.10 EWM30094.1 - 0.011 14.7 0.0 2 7.2 0.0 2.7 2 1 1 3 3 3 0 Stage IV sporulation protein A (spore_IV_A) FeoB_N PF02421.18 EWM30094.1 - 0.013 15.0 0.2 2.4 7.7 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B IIGP PF05049.13 EWM30094.1 - 0.054 12.5 0.3 0.19 10.8 0.0 1.9 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Septin PF00735.18 EWM30094.1 - 0.067 12.5 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Septin DUF4202 PF13875.6 EWM30094.1 - 0.072 13.0 1.8 0.11 12.4 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4202) Hemerythrin PF01814.23 EWM30094.1 - 0.8 10.3 7.6 0.93 10.1 0.8 3.9 4 0 0 4 4 4 0 Hemerythrin HHE cation binding domain YkyA PF10368.9 EWM30094.1 - 4.8 6.8 6.7 0.21 11.2 0.2 2.0 3 0 0 3 3 3 0 Putative cell-wall binding lipoprotein Dynamin_N PF00350.23 EWM30095.1 - 2e-22 80.0 0.0 1.4e-10 41.5 0.0 2.6 1 1 1 2 2 2 2 Dynamin family MMR_HSR1 PF01926.23 EWM30095.1 - 1.9e-11 44.1 0.0 6.4e-11 42.3 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EWM30095.1 - 8.4e-06 25.5 0.0 4.6e-05 23.0 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EWM30095.1 - 1.8e-05 24.7 0.1 0.045 13.6 0.1 2.8 1 1 1 2 2 2 2 RsgA GTPase Ras PF00071.22 EWM30095.1 - 0.003 17.2 0.0 0.062 12.9 0.0 2.5 1 1 1 2 2 2 1 Ras family Spore_IV_A PF09547.10 EWM30095.1 - 0.0095 14.9 0.0 1.9 7.4 0.0 2.7 2 1 1 3 3 3 1 Stage IV sporulation protein A (spore_IV_A) FeoB_N PF02421.18 EWM30095.1 - 0.013 15.1 0.2 2.3 7.7 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B IIGP PF05049.13 EWM30095.1 - 0.052 12.6 0.3 0.17 10.9 0.0 1.9 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Septin PF00735.18 EWM30095.1 - 0.062 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Septin DUF4202 PF13875.6 EWM30095.1 - 0.065 13.1 1.8 0.1 12.5 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4202) YkyA PF10368.9 EWM30095.1 - 0.16 11.6 1.5 0.19 11.4 0.2 1.7 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein PduV-EutP PF10662.9 EWM30095.1 - 0.16 11.7 0.0 1 9.1 0.0 2.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Hemerythrin PF01814.23 EWM30095.1 - 0.95 10.1 7.3 4.2 8.0 3.0 3.4 3 1 0 3 3 3 0 Hemerythrin HHE cation binding domain DUF5484 PF17583.2 EWM30096.1 - 0.082 12.6 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5484) RHS PF03527.14 EWM30096.1 - 0.09 12.5 0.2 0.41 10.4 0.1 2.1 2 0 0 2 2 2 0 RHS protein Lipid_DES PF08557.10 EWM30097.1 - 4.2e-17 61.3 0.5 4.2e-17 61.3 0.5 1.9 2 0 0 2 2 2 1 Sphingolipid Delta4-desaturase (DES) FA_desaturase PF00487.24 EWM30097.1 - 1.5e-11 44.7 3.2 2.6e-11 43.9 3.2 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DnaJ PF00226.31 EWM30098.1 - 7.6e-23 80.4 3.7 1.1e-22 79.9 3.7 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 EWM30098.1 - 4.7e-20 72.2 0.0 6.6e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain Lipase_3 PF01764.25 EWM30099.1 - 1e-05 25.4 1.0 8e-05 22.5 0.8 2.3 2 1 0 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EWM30099.1 - 0.00029 21.5 0.7 0.00029 21.5 0.7 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EWM30099.1 - 0.023 14.4 0.2 0.042 13.6 0.2 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF2048 PF09752.9 EWM30099.1 - 0.03 13.4 0.1 0.047 12.8 0.1 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Hydrolase_4 PF12146.8 EWM30099.1 - 0.033 13.5 0.0 0.058 12.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EWM30099.1 - 0.047 13.3 0.0 0.077 12.6 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 EWM30099.1 - 0.085 12.5 0.1 0.22 11.1 0.1 1.6 1 0 0 1 1 1 0 Putative esterase Thioesterase PF00975.20 EWM30099.1 - 0.093 12.8 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain UPF0051 PF01458.17 EWM30100.1 - 4.9e-49 167.0 0.2 7.3e-49 166.4 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) UCR_Fe-S_N PF10399.9 EWM30100.1 - 0.079 12.3 2.4 0.34 10.3 2.2 2.2 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal LAGLIDADG_3 PF14528.6 EWM30100.1 - 0.1 12.9 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 LAGLIDADG-like domain adh_short PF00106.25 EWM30101.1 - 6.1e-23 81.3 0.0 4.9e-19 68.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EWM30101.1 - 4.7e-10 39.4 0.0 7.8e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM30101.1 - 0.00099 19.1 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Glyco_hydro_18 PF00704.28 EWM30102.1 - 8.8e-20 71.6 0.0 1.2e-19 71.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 UAA PF08449.11 EWM30103.1 - 2.3e-53 181.4 13.2 2.7e-53 181.2 13.2 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EWM30103.1 - 4e-05 23.8 22.6 0.00079 19.6 10.4 2.3 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 EWM30103.1 - 0.0017 17.7 10.5 0.0024 17.3 10.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family Biotin_lipoyl PF00364.22 EWM30104.1 - 8.9e-20 70.3 1.0 1.1e-19 70.0 1.0 1.1 1 0 0 1 1 1 1 Biotin-requiring enzyme QRPTase_N PF02749.16 EWM30104.1 - 0.11 12.6 0.0 0.34 11.0 0.0 1.8 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain Biotin_lipoyl_2 PF13533.6 EWM30104.1 - 0.15 11.9 0.0 2.1 8.2 0.0 2.1 1 1 1 2 2 2 0 Biotin-lipoyl like GCV_H PF01597.19 EWM30104.1 - 0.16 11.8 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage H-protein Erythro_esteras PF05139.14 EWM30105.1 - 1.6e-86 291.3 2.6 1.8e-86 291.1 2.6 1.0 1 0 0 1 1 1 1 Erythromycin esterase Erythro_esteras PF05139.14 EWM30106.1 - 2e-97 327.1 2.0 2.8e-97 326.6 2.0 1.2 1 0 0 1 1 1 1 Erythromycin esterase Surp PF01805.20 EWM30106.1 - 0.1 12.6 0.0 0.37 10.8 0.0 1.9 2 0 0 2 2 2 0 Surp module IF-2B PF01008.17 EWM30107.1 - 2.3e-77 260.0 0.2 3e-77 259.6 0.2 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family APH PF01636.23 EWM30107.1 - 1.7e-17 64.1 0.1 6e-17 62.4 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EWM30107.1 - 0.0017 18.0 0.0 0.0029 17.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase tRNA_U5-meth_tr PF05958.11 EWM30108.1 - 0.00013 21.1 0.0 0.00025 20.1 0.0 1.4 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase MethyltransfD12 PF02086.15 EWM30108.1 - 0.023 14.4 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase TPR_1 PF00515.28 EWM30109.1 - 7.9e-15 54.0 0.0 0.0036 17.0 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EWM30109.1 - 5e-12 45.0 3.9 0.0055 16.7 0.0 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 EWM30109.1 - 6.3e-11 42.4 4.6 0.00013 22.2 1.2 3.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 EWM30109.1 - 6.8e-08 32.1 0.5 0.43 10.3 0.1 4.8 5 0 0 5 5 4 3 TPR repeat TPR_8 PF13181.6 EWM30109.1 - 3.5e-06 26.8 0.1 1.1 9.7 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 EWM30109.1 - 4.3e-06 26.8 5.5 1.2 9.4 1.3 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 EWM30109.1 - 2.5e-05 24.8 16.9 0.075 13.7 0.3 5.0 3 1 3 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 EWM30109.1 - 8.6e-05 22.3 7.2 0.25 11.3 0.1 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 EWM30109.1 - 0.00068 19.0 1.0 9.1 5.8 0.1 3.5 3 0 0 3 3 3 1 SHNi-TPR TPR_14 PF13428.6 EWM30109.1 - 0.0016 19.1 14.7 0.78 10.7 0.3 5.5 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EWM30109.1 - 0.0095 15.9 5.5 0.74 10.0 0.1 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF3856 PF12968.7 EWM30109.1 - 0.029 14.4 0.4 1.1 9.3 0.1 2.7 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) SnoaL_2 PF12680.7 EWM30109.1 - 0.07 13.8 3.0 0.073 13.7 0.3 2.2 2 0 0 2 2 2 0 SnoaL-like domain DegS PF05384.11 EWM30109.1 - 0.1 12.1 0.1 0.16 11.4 0.1 1.2 1 0 0 1 1 1 0 Sensor protein DegS TPR_4 PF07721.14 EWM30109.1 - 0.32 11.7 6.9 27 5.8 0.5 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat PAPS_reduct PF01507.19 EWM30110.1 - 7.1e-06 26.2 0.0 0.00022 21.3 0.0 2.0 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family Syja_N PF02383.18 EWM30111.1 - 1.8e-72 244.4 0.0 2.2e-72 244.1 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain PAPS_reduct PF01507.19 EWM30113.1 - 1.8e-12 47.7 0.0 3e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family TraI_2B PF18340.1 EWM30113.1 - 0.018 15.1 0.3 0.035 14.2 0.3 1.4 1 0 0 1 1 1 0 DNA relaxase TraI 2B/2B-like domain TT_ORF2a PF08197.11 EWM30113.1 - 0.035 14.1 0.6 0.13 12.3 0.1 2.1 2 0 0 2 2 2 0 pORF2a truncated protein Pkinase PF00069.25 EWM30117.1 - 1.4e-29 103.3 0.0 7.3e-24 84.5 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EWM30117.1 - 3e-19 69.3 0.0 3.1e-11 43.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EWM30117.1 - 0.075 11.8 0.0 0.098 11.4 0.0 1.3 1 1 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 EWM30118.1 - 1.4e-29 103.3 0.0 7.3e-24 84.5 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EWM30118.1 - 3e-19 69.3 0.0 3.1e-11 43.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EWM30118.1 - 0.075 11.8 0.0 0.098 11.4 0.0 1.3 1 1 0 1 1 1 0 Fungal protein kinase HAGH_C PF16123.5 EWM30120.1 - 6.6e-25 87.4 0.0 9.5e-25 86.9 0.0 1.2 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 EWM30120.1 - 1.1e-09 38.6 0.1 2.1e-07 31.1 0.1 2.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EWM30120.1 - 0.078 12.5 0.0 0.15 11.6 0.0 1.6 1 1 0 1 1 1 0 Beta-lactamase superfamily domain HAGH_C PF16123.5 EWM30121.1 - 7.5e-25 87.3 0.0 1.1e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 EWM30121.1 - 1.3e-09 38.4 0.1 2.5e-07 30.9 0.1 3.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EWM30121.1 - 0.09 12.3 0.0 0.14 11.6 0.0 1.5 1 1 0 1 1 1 0 Beta-lactamase superfamily domain SET PF00856.28 EWM30122.1 - 0.006 17.0 0.0 0.023 15.1 0.0 1.9 2 1 0 2 2 2 1 SET domain DUF2207 PF09972.9 EWM30124.1 - 9.1e-05 21.4 0.0 0.00012 21.0 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF418 PF04235.12 EWM30124.1 - 0.01 15.8 2.1 0.019 14.9 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF418) Glyco_trans_2_3 PF13632.6 EWM30124.1 - 0.067 13.1 0.2 0.12 12.3 0.2 1.4 1 0 0 1 1 1 0 Glycosyl transferase family group 2 DUF4061 PF13270.6 EWM30124.1 - 0.075 13.4 3.4 0.13 12.6 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) UPF0242 PF06785.11 EWM30125.1 - 0.089 12.9 4.3 0.12 12.5 4.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus MFS_1 PF07690.16 EWM30127.1 - 4.8e-21 75.1 26.3 4.8e-21 75.1 26.3 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF4407 PF14362.6 EWM30129.1 - 0.035 13.5 3.7 0.067 12.5 3.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GAS PF13851.6 EWM30129.1 - 0.041 13.2 0.5 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4763 PF15960.5 EWM30129.1 - 0.081 12.2 0.8 8.5 5.6 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) CEP63 PF17045.5 EWM30129.1 - 0.1 12.5 1.6 0.35 10.7 0.2 2.0 2 0 0 2 2 2 0 Centrosomal protein of 63 kDa BST2 PF16716.5 EWM30129.1 - 0.11 13.1 3.3 0.72 10.5 0.5 2.6 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 DUF4201 PF13870.6 EWM30129.1 - 0.14 11.9 1.5 0.38 10.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) HALZ PF02183.18 EWM30129.1 - 0.15 12.3 1.1 0.29 11.4 0.3 1.9 2 0 0 2 2 1 0 Homeobox associated leucine zipper TMCO5 PF14992.6 EWM30129.1 - 0.17 11.4 0.0 0.25 10.9 0.0 1.1 1 0 0 1 1 1 0 TMCO5 family bZIP_1 PF00170.21 EWM30129.1 - 0.18 11.9 0.1 0.18 11.9 0.1 3.3 4 0 0 4 4 4 0 bZIP transcription factor NYD-SP28 PF14772.6 EWM30129.1 - 0.63 10.1 5.2 0.4 10.7 0.8 2.7 3 0 0 3 3 3 0 Sperm tail DUF2383 PF09537.10 EWM30129.1 - 1.1 9.6 3.2 1.1 9.6 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF2383) TolA_bind_tri PF16331.5 EWM30129.1 - 3 8.0 7.8 7.5 6.7 1.3 2.8 2 0 0 2 2 2 0 TolA binding protein trimerisation Lar_restr_allev PF14354.6 EWM30130.1 - 0.0024 18.2 0.1 0.0054 17.1 0.1 1.6 1 0 0 1 1 1 1 Restriction alleviation protein Lar zf-CHC2 PF01807.20 EWM30130.1 - 0.13 12.1 0.6 1 9.2 0.6 2.1 1 1 0 1 1 1 0 CHC2 zinc finger Transglut_core PF01841.19 EWM30131.1 - 7.9e-11 42.4 0.3 2.5e-10 40.8 0.2 1.9 2 0 0 2 2 2 1 Transglutaminase-like superfamily Rad4 PF03835.15 EWM30131.1 - 7.2e-07 29.0 0.0 1.6e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain MCM_N PF14551.6 EWM30133.1 - 2e-13 50.8 0.0 3.1e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 MCM N-terminal domain AAA_25 PF13481.6 EWM30134.1 - 6.2e-24 84.7 0.0 1.7e-23 83.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.15 EWM30134.1 - 4.9e-13 49.0 0.0 7e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Toprim_2 PF13155.6 EWM30134.1 - 4.4e-11 43.1 0.0 1.2e-10 41.6 0.0 1.8 2 0 0 2 2 1 1 Toprim-like Toprim_4 PF13662.6 EWM30134.1 - 2.8e-07 30.9 0.0 2.8e-06 27.7 0.0 2.3 2 0 0 2 2 2 1 Toprim domain AAA_22 PF13401.6 EWM30134.1 - 1.6e-06 28.4 0.0 1.5e-05 25.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain ATPase PF06745.13 EWM30134.1 - 1.8e-05 24.2 0.0 3.3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 KaiC Toprim_3 PF13362.6 EWM30134.1 - 0.00013 22.2 0.0 0.0004 20.7 0.0 1.8 2 0 0 2 2 1 1 Toprim domain T2SSE PF00437.20 EWM30134.1 - 0.0015 17.7 0.0 0.0023 17.1 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 EWM30134.1 - 0.0015 19.0 0.1 0.0029 18.1 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EWM30134.1 - 0.0022 18.4 0.0 0.0061 17.0 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 EWM30134.1 - 0.0038 17.2 0.7 0.0062 16.5 0.1 1.7 2 0 0 2 2 1 1 NACHT domain AAA_29 PF13555.6 EWM30134.1 - 0.0041 16.8 0.9 0.018 14.8 0.2 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EWM30134.1 - 0.0041 17.6 0.2 0.0081 16.7 0.2 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EWM30134.1 - 0.0074 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RsgA_GTPase PF03193.16 EWM30134.1 - 0.0082 16.1 0.1 0.019 14.9 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase cobW PF02492.19 EWM30134.1 - 0.014 15.0 0.0 0.038 13.6 0.1 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 EWM30134.1 - 0.029 13.9 0.3 0.56 9.7 0.1 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 EWM30134.1 - 0.031 14.0 0.1 0.061 13.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 EWM30134.1 - 0.032 14.3 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 EWM30134.1 - 0.04 13.6 0.3 0.14 11.8 0.3 2.0 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 EWM30134.1 - 0.052 13.6 0.3 0.15 12.1 0.3 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EWM30134.1 - 0.056 13.7 0.3 0.18 12.0 0.2 1.9 1 1 1 2 2 2 0 AAA domain NTPase_1 PF03266.15 EWM30134.1 - 0.077 12.9 0.3 0.16 11.9 0.1 1.6 2 0 0 2 2 1 0 NTPase AAA_21 PF13304.6 EWM30134.1 - 0.09 12.6 0.7 0.27 11.0 0.1 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 EWM30134.1 - 0.19 12.2 0.1 0.6 10.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain DEAD PF00270.29 EWM30134.1 - 2.1 8.1 3.2 7.2 6.3 0.4 2.4 2 1 1 3 3 3 0 DEAD/DEAH box helicase MCM PF00493.23 EWM30135.1 - 4.4e-07 29.2 0.0 5.6e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 MCM P-loop domain SNAP PF14938.6 EWM30136.1 - 7.8e-38 130.5 9.1 9.1e-38 130.3 9.1 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 EWM30136.1 - 2e-06 28.0 3.9 0.0067 16.7 1.0 3.1 1 1 2 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EWM30136.1 - 1.4e-05 24.7 7.2 0.042 13.7 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EWM30136.1 - 4.8e-05 23.1 4.6 1.6 9.0 0.1 4.5 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EWM30136.1 - 5e-05 23.1 7.3 0.42 10.9 0.1 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 EWM30136.1 - 0.00022 21.2 8.3 0.19 12.0 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat MIT PF04212.18 EWM30136.1 - 0.0067 16.5 10.2 1.5 9.0 0.1 3.5 3 1 0 3 3 3 2 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 EWM30136.1 - 0.014 15.1 8.4 0.47 10.2 0.1 4.3 4 1 1 5 5 5 0 TPR repeat TOM20_plant PF06552.12 EWM30136.1 - 0.015 15.0 0.3 0.84 9.3 0.0 2.1 1 1 1 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_14 PF13428.6 EWM30136.1 - 0.021 15.6 2.5 29 5.9 0.0 4.1 3 2 2 5 5 5 0 Tetratricopeptide repeat DHR-2 PF06920.13 EWM30136.1 - 0.037 12.7 0.1 0.11 11.1 0.0 1.5 1 1 1 2 2 2 0 Dock homology region 2 RPN7 PF10602.9 EWM30136.1 - 0.05 13.3 2.3 0.47 10.1 0.0 2.7 1 1 1 3 3 3 0 26S proteasome subunit RPN7 TPR_6 PF13174.6 EWM30136.1 - 0.067 13.9 5.2 35 5.3 0.0 4.8 2 1 2 4 4 4 0 Tetratricopeptide repeat NRBF2_MIT PF17169.4 EWM30136.1 - 0.18 12.1 1.7 6.2 7.1 0.1 2.7 1 1 0 2 2 2 0 MIT domain of nuclear receptor-binding factor 2 TPR_19 PF14559.6 EWM30136.1 - 0.24 12.0 3.6 0.84 10.2 0.0 2.8 1 1 2 3 3 3 0 Tetratricopeptide repeat NSF PF02071.20 EWM30136.1 - 1.1 10.3 0.2 1.1 10.3 0.2 6.6 8 2 1 9 9 6 0 Aromatic-di-Alanine (AdAR) repeat Thiolase_N PF00108.23 EWM30137.1 - 1.4e-90 303.2 0.2 2e-90 302.7 0.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EWM30137.1 - 5e-43 145.7 2.9 3.1e-42 143.1 0.5 2.4 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EWM30137.1 - 7.4e-05 22.4 1.3 7.4e-05 22.4 1.3 2.8 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EWM30137.1 - 0.24 11.3 6.1 1.2 9.0 0.1 3.3 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III MCM PF00493.23 EWM30138.1 - 6e-33 113.8 0.0 8.4e-33 113.3 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 EWM30138.1 - 1.7e-26 92.4 1.5 2.9e-26 91.7 1.5 1.4 1 0 0 1 1 1 1 MCM AAA-lid domain DUF2201_N PF13203.6 EWM30138.1 - 0.46 10.0 3.6 1.2 8.6 3.6 1.8 1 1 0 1 1 1 0 Putative metallopeptidase domain PBP1_TM PF14812.6 EWM30138.1 - 0.64 10.4 9.9 0.18 12.2 6.5 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MCM PF00493.23 EWM30139.1 - 7.5e-27 93.9 0.1 9.3e-26 90.3 0.0 2.1 2 0 0 2 2 2 1 MCM P-loop domain MCM_lid PF17855.1 EWM30139.1 - 2.2e-26 92.1 1.5 4e-26 91.3 1.5 1.4 1 0 0 1 1 1 1 MCM AAA-lid domain DUF2201_N PF13203.6 EWM30139.1 - 0.55 9.8 3.2 1.5 8.4 3.2 1.8 1 1 0 1 1 1 0 Putative metallopeptidase domain PBP1_TM PF14812.6 EWM30139.1 - 8.4 6.8 13.5 0.24 11.8 6.5 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2009 PF09418.10 EWM30140.1 - 1.9e-23 83.3 1.2 2.4e-23 83.0 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) DUF2009 PF09418.10 EWM30141.1 - 1.6e-135 452.7 0.0 1.9e-135 452.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) Trp_Tyr_perm PF03222.13 EWM30142.1 - 2.2e-72 244.3 17.3 3.2e-72 243.8 17.3 1.1 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Aa_trans PF01490.18 EWM30142.1 - 2.7e-05 23.1 4.7 2.7e-05 23.1 4.7 1.9 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein GFO_IDH_MocA PF01408.22 EWM30143.1 - 5.5e-21 75.6 0.2 1.1e-20 74.7 0.2 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EWM30143.1 - 0.011 16.4 0.2 0.018 15.7 0.2 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Sulfatase PF00884.23 EWM30144.1 - 1.2e-10 41.3 0.8 3.9e-09 36.3 0.8 2.4 1 1 0 1 1 1 1 Sulfatase DUF229 PF02995.17 EWM30144.1 - 9.4e-07 27.8 0.0 2e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4149 PF13664.6 EWM30144.1 - 0.0065 16.8 3.6 0.073 13.4 1.2 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF4149) NARP1 PF12569.8 EWM30147.1 - 6.5e-128 427.9 11.8 8.3e-125 417.6 8.0 4.0 2 2 0 3 3 3 1 NMDA receptor-regulated protein 1 TPR_14 PF13428.6 EWM30147.1 - 2.2e-07 31.1 25.2 0.066 14.1 2.1 9.1 7 2 2 9 9 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 EWM30147.1 - 3.2e-07 29.9 0.5 0.013 15.1 0.0 4.0 4 0 0 4 4 4 2 TPR repeat TPR_19 PF14559.6 EWM30147.1 - 3.3e-06 27.5 24.6 0.014 15.9 0.5 8.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 EWM30147.1 - 2.4e-05 24.1 28.3 0.088 13.0 1.1 8.5 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 EWM30147.1 - 0.0033 17.2 17.0 0.23 11.3 0.1 6.3 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 EWM30147.1 - 0.0045 16.8 5.1 5.4 7.0 0.1 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EWM30147.1 - 0.0097 16.2 18.4 0.49 10.7 0.3 6.0 5 1 2 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 EWM30147.1 - 0.021 14.8 8.5 2.9 8.1 0.0 5.3 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 EWM30147.1 - 0.024 14.8 16.5 0.43 10.9 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 EWM30147.1 - 0.061 14.0 34.0 2.5 8.8 11.5 8.8 8 2 0 8 8 7 0 Tetratricopeptide repeat TAF4 PF05236.14 EWM30147.1 - 0.42 10.3 7.8 1.1 8.9 7.8 1.7 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF4355 PF14265.6 EWM30147.1 - 1.2 9.4 10.3 3.8 7.8 10.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) SRP_TPR_like PF17004.5 EWM30147.1 - 8.8 6.4 9.2 3.2 7.8 0.1 3.5 4 0 0 4 4 4 0 Putative TPR-like repeat Pkinase PF00069.25 EWM30150.1 - 2.3e-24 86.2 0.0 4.5e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM30150.1 - 2e-10 40.4 0.0 2e-10 40.4 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase TFIIA PF03153.13 EWM30150.1 - 0.066 13.2 30.7 0.14 12.1 30.7 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit 2OG-FeII_Oxy_2 PF13532.6 EWM30151.1 - 1.3e-14 54.9 0.0 3e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily STAR_dimer PF16544.5 EWM30151.1 - 0.064 12.8 0.1 13 5.4 0.1 3.1 3 0 0 3 3 3 0 Homodimerisation region of STAR domain protein DUF2749 PF10907.8 EWM30152.1 - 0.2 11.9 0.7 2.7 8.2 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) Ribosomal_L28 PF00830.19 EWM30153.1 - 2.2e-13 50.2 6.0 2.8e-13 49.8 6.0 1.2 1 0 0 1 1 1 1 Ribosomal L28 family DUF4881 PF16222.5 EWM30153.1 - 0.15 11.9 0.0 0.18 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4881) U-box PF04564.15 EWM30154.1 - 2.9e-21 75.4 0.1 3.8e-21 75.0 0.1 1.1 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 EWM30154.1 - 5.3e-05 23.3 0.0 8.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 EWM30154.1 - 0.095 12.5 0.0 0.36 10.7 0.0 1.8 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit CDC45 PF02724.14 EWM30154.1 - 1.2 7.3 7.4 1.2 7.3 7.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EWM30154.1 - 4.4 5.4 16.6 6.1 4.9 16.6 1.2 1 0 0 1 1 1 0 Nop14-like family Tim54 PF11711.8 EWM30154.1 - 7.6 5.2 11.1 2.1 7.1 8.2 1.5 1 1 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Cyclin_N PF00134.23 EWM30155.1 - 3.1e-13 49.6 0.2 4.4e-12 45.9 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain RB_B PF01857.20 EWM30155.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain FA_desaturase PF00487.24 EWM30156.1 - 1.1e-16 61.5 17.9 1.1e-16 61.5 17.9 2.1 1 1 1 2 2 2 1 Fatty acid desaturase PMM PF03332.13 EWM30159.1 - 5.9e-102 340.1 0.2 7e-102 339.9 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 EWM30159.1 - 9.2e-08 32.1 0.0 2e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EWM30159.1 - 0.057 12.9 0.0 0.5 9.9 0.0 1.9 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Ank_2 PF12796.7 EWM30160.1 - 1.3e-37 128.3 3.4 4.3e-10 40.0 0.0 4.1 2 1 3 5 5 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EWM30160.1 - 8e-27 93.3 2.4 6.1e-06 26.7 0.0 6.3 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EWM30160.1 - 4.7e-24 84.1 9.1 2.2e-06 27.8 0.0 7.0 3 2 5 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EWM30160.1 - 9.8e-24 80.9 1.5 0.00081 19.7 0.0 7.9 7 1 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 EWM30160.1 - 2.2e-18 65.8 15.0 0.0063 16.9 0.0 7.5 7 0 0 7 7 7 5 Ankyrin repeat TPR_2 PF07719.17 EWM30160.1 - 1.6e-08 34.0 4.0 0.008 16.2 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EWM30160.1 - 1.3e-06 28.0 0.6 0.5 10.3 0.5 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EWM30160.1 - 5.3e-06 27.0 12.3 0.0004 21.0 0.6 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EWM30160.1 - 0.00021 21.8 7.8 0.0053 17.3 0.0 3.7 3 1 2 5 5 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EWM30160.1 - 0.0009 19.4 0.1 0.038 14.2 0.0 2.4 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EWM30160.1 - 0.027 14.8 2.9 0.64 10.4 0.1 3.5 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EWM30160.1 - 0.42 10.9 2.6 30 5.2 0.2 3.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 EWM30160.1 - 4.2 8.5 11.9 5.2 8.2 0.6 4.9 3 1 2 5 5 4 0 Tetratricopeptide repeat Alg6_Alg8 PF03155.15 EWM30161.1 - 9.3e-138 460.2 10.4 1.2e-137 459.9 10.4 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family DUF3522 PF12036.8 EWM30161.1 - 9.9 6.4 10.1 0.12 12.6 0.5 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3522) CDC50 PF03381.15 EWM30162.1 - 6.9e-85 285.0 0.0 9e-85 284.6 0.0 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family zf-met PF12874.7 EWM30163.1 - 2.6e-06 27.6 1.1 4.3e-06 26.9 1.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EWM30163.1 - 5.7e-06 26.5 0.7 1.1e-05 25.6 0.7 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.12 EWM30163.1 - 0.00029 20.6 1.0 0.00055 19.6 1.0 1.5 1 0 0 1 1 1 1 U1 zinc finger DUF501 PF04417.12 EWM30163.1 - 0.088 12.6 0.2 0.23 11.3 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF501) SURF2 PF05477.11 EWM30163.1 - 7.6 6.2 11.1 0.68 9.6 5.8 1.9 2 1 0 2 2 2 0 Surfeit locus protein 2 (SURF2) Metallophos PF00149.28 EWM30166.1 - 1.8e-23 84.1 0.1 3e-23 83.4 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Sec2p PF06428.11 EWM30166.1 - 0.0016 18.4 1.9 0.003 17.5 1.9 1.4 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p NYD-SP28 PF14772.6 EWM30166.1 - 0.11 12.5 1.2 0.22 11.6 1.2 1.4 1 0 0 1 1 1 0 Sperm tail SET PF00856.28 EWM30169.1 - 4.8e-13 49.8 0.4 2.3e-11 44.3 0.0 3.1 3 1 0 3 3 3 1 SET domain AP3D1 PF06375.11 EWM30169.1 - 0.41 10.9 17.2 0.9 9.8 5.9 2.3 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 DUF4820 PF16091.5 EWM30169.1 - 2 7.8 5.8 0.23 10.8 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) CPSF100_C PF13299.6 EWM30169.1 - 6.7 6.9 10.1 18 5.5 1.7 3.1 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal ETRAMP PF09716.10 EWM30169.1 - 7.5 6.7 6.2 50 4.1 0.0 2.4 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Methyltransf_23 PF13489.6 EWM30170.1 - 1.4e-12 47.7 0.0 2.4e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM30170.1 - 3.5e-11 43.6 0.5 1.4e-10 41.7 0.5 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM30170.1 - 5e-11 43.2 0.2 1.6e-10 41.6 0.2 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EWM30170.1 - 3.3e-10 40.6 0.0 6e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EWM30170.1 - 0.0004 20.2 0.0 0.00061 19.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EWM30170.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain CCD48 PF15799.5 EWM30170.1 - 0.19 10.0 0.1 0.34 9.1 0.0 1.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 48 Pcc1 PF09341.10 EWM30171.1 - 6.5e-17 61.4 0.2 9.2e-17 60.9 0.2 1.2 1 0 0 1 1 1 1 Transcription factor Pcc1 HEAT PF02985.22 EWM30172.1 - 2.6e-34 114.3 50.5 0.0096 16.1 0.1 23.7 27 0 0 27 27 25 8 HEAT repeat HEAT_EZ PF13513.6 EWM30172.1 - 1.4e-29 102.1 79.1 0.001 19.5 0.6 23.2 22 3 3 25 25 25 9 HEAT-like repeat HEAT_2 PF13646.6 EWM30172.1 - 1.9e-22 79.5 63.7 7e-05 23.1 0.3 16.8 13 4 3 18 18 17 9 HEAT repeats Vac14_Fab1_bd PF12755.7 EWM30172.1 - 1.7e-14 54.2 0.0 0.6 10.7 0.0 8.9 7 1 1 8 8 8 5 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 EWM30172.1 - 5.9e-14 52.2 0.0 0.00031 20.4 0.0 7.7 8 1 0 8 8 8 2 CLASP N terminal Cnd1 PF12717.7 EWM30172.1 - 1e-11 45.2 0.1 0.43 10.6 0.0 8.5 6 1 3 9 9 9 2 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 EWM30172.1 - 7.5e-10 39.2 0.0 1.1 9.3 0.0 6.0 6 0 0 6 6 6 3 Parkin co-regulated protein Adaptin_N PF01602.20 EWM30172.1 - 8.9e-09 34.4 1.1 0.016 13.8 0.0 6.3 6 1 0 7 7 7 2 Adaptin N terminal region UME PF08064.13 EWM30172.1 - 1.4e-05 24.9 2.6 10 6.1 0.0 7.9 8 0 0 8 8 7 0 UME (NUC010) domain Ipi1_N PF12333.8 EWM30172.1 - 1.7e-05 25.4 0.0 3.7 8.2 0.1 6.5 7 0 0 7 7 5 1 Rix1 complex component involved in 60S ribosome maturation RIX1 PF08167.12 EWM30172.1 - 9.8e-05 22.2 3.3 0.51 10.0 0.2 4.7 4 0 0 4 4 4 2 rRNA processing/ribosome biogenesis IFRD PF05004.13 EWM30172.1 - 0.00018 20.8 10.7 0.84 8.7 0.0 7.3 9 1 0 9 9 9 1 Interferon-related developmental regulator (IFRD) RTP1_C1 PF10363.9 EWM30172.1 - 0.00039 20.6 0.3 3.1 8.0 0.0 5.1 4 0 0 4 4 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Tti2 PF10521.9 EWM30172.1 - 0.0016 18.0 2.5 7.9 5.9 0.0 5.3 5 0 0 5 5 5 1 Tti2 family Dopey_N PF04118.14 EWM30172.1 - 0.024 13.8 0.0 6.5 5.8 0.0 4.4 6 0 0 6 6 6 0 Dopey, N-terminal DNA_pol_phi PF04931.13 EWM30172.1 - 0.052 11.7 1.3 0.67 8.0 0.5 2.9 3 0 0 3 3 3 0 DNA polymerase phi PIN_6 PF17146.4 EWM30172.1 - 0.099 13.1 0.0 6.2 7.4 0.0 2.8 2 0 0 2 2 2 0 PIN domain of ribonuclease Cohesin_HEAT PF12765.7 EWM30172.1 - 0.15 12.4 18.5 22 5.5 0.0 9.1 9 0 0 9 9 9 0 HEAT repeat associated with sister chromatid cohesion DUF4042 PF13251.6 EWM30172.1 - 0.42 10.3 6.3 35 4.1 0.0 6.3 8 0 0 8 8 7 0 Domain of unknown function (DUF4042) MMS19_C PF12460.8 EWM30172.1 - 1.8 7.6 8.0 9 5.3 0.0 5.3 5 1 0 6 6 6 0 RNAPII transcription regulator C-terminal Acyl-CoA_dh_1 PF00441.24 EWM30173.1 - 5.7e-47 159.7 4.4 8.8e-47 159.1 4.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EWM30173.1 - 1.8e-26 93.0 0.0 3.2e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EWM30173.1 - 9.2e-26 89.9 0.0 2.1e-25 88.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EWM30173.1 - 1.5e-19 70.6 3.4 1.5e-19 70.6 3.4 1.9 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 EWM30173.1 - 0.063 13.8 0.0 0.12 13.0 0.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal URO-D PF01208.17 EWM30174.1 - 1.9e-77 260.7 0.1 2.3e-77 260.5 0.1 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) PKD_channel PF08016.12 EWM30174.1 - 0.13 10.9 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Polycystin cation channel RdRP_1 PF00680.20 EWM30174.1 - 0.14 10.6 0.0 0.2 10.1 0.0 1.1 1 0 0 1 1 1 0 RNA dependent RNA polymerase Voldacs PF03517.13 EWM30175.1 - 1.1e-16 61.2 0.7 5.4e-16 59.0 0.7 2.0 1 1 0 1 1 1 1 Regulator of volume decrease after cellular swelling Herpes_LMP1 PF05297.11 EWM30176.1 - 0.13 11.4 5.8 0.021 14.0 0.7 2.0 1 1 1 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) GBP PF02263.19 EWM30177.1 - 6.2e-14 51.9 0.0 1.6e-13 50.6 0.0 1.7 1 1 0 1 1 1 1 Guanylate-binding protein, N-terminal domain TolA_bind_tri PF16331.5 EWM30177.1 - 4.3 7.5 9.3 1.8 8.7 2.2 3.0 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF760 PF05542.11 EWM30178.1 - 2.9e-17 62.8 0.0 6.8e-09 36.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF760) Nop14 PF04147.12 EWM30178.1 - 0.19 9.9 2.7 0.25 9.5 2.7 1.1 1 0 0 1 1 1 0 Nop14-like family zf-C3HC4_3 PF13920.6 EWM30179.1 - 0.011 15.6 1.5 0.016 15.1 1.5 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EWM30179.1 - 0.018 15.4 2.0 0.027 14.8 2.0 1.2 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 EWM30179.1 - 0.03 14.3 0.6 0.046 13.7 0.6 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 EWM30179.1 - 0.077 12.9 0.7 0.12 12.3 0.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 EWM30179.1 - 0.17 12.0 2.0 0.25 11.5 2.0 1.2 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_2 PF13923.6 EWM30179.1 - 0.23 11.4 2.4 0.4 10.6 2.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EWM30179.1 - 0.24 11.3 2.8 0.41 10.5 2.8 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 LysM PF01476.20 EWM30180.1 - 2.2e-06 27.6 0.0 0.021 14.9 0.0 2.6 2 0 0 2 2 2 2 LysM domain PDZ PF00595.24 EWM30180.1 - 0.0025 18.1 0.1 0.0048 17.2 0.1 1.4 1 0 0 1 1 1 1 PDZ domain LysM PF01476.20 EWM30181.1 - 1.5e-06 28.1 0.0 0.018 15.1 0.0 2.5 2 0 0 2 2 2 2 LysM domain PDZ PF00595.24 EWM30181.1 - 0.002 18.4 0.1 0.0039 17.5 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EWM30181.1 - 0.12 12.2 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 PDZ domain PDZ_2 PF13180.6 EWM30181.1 - 0.17 12.2 0.0 0.41 11.0 0.0 1.6 1 0 0 1 1 1 0 PDZ domain zinc_ribbon_6 PF14599.6 EWM30182.1 - 9.8e-20 70.3 0.1 9.8e-20 70.3 0.1 2.6 3 0 0 3 3 3 1 Zinc-ribbon zf-CHY PF05495.12 EWM30182.1 - 7.9e-18 64.7 21.1 7.9e-18 64.7 21.1 4.1 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 EWM30182.1 - 6.1e-08 32.9 6.3 6.1e-08 32.9 6.3 4.9 3 1 1 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 EWM30182.1 - 1.1e-06 28.5 7.2 1.1e-06 28.5 7.2 4.7 3 3 1 4 4 4 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EWM30182.1 - 6.7e-06 26.0 2.3 6.7e-06 26.0 2.3 3.6 3 1 1 4 4 4 1 RING-type zinc-finger Hemerythrin PF01814.23 EWM30182.1 - 4.7e-05 24.0 4.5 0.00011 22.8 3.1 2.2 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain zf-C3HC4_2 PF13923.6 EWM30182.1 - 0.0017 18.1 7.3 0.0017 18.1 7.3 4.9 5 2 1 6 6 6 1 Zinc finger, C3HC4 type (RING finger) GDA1_CD39 PF01150.17 EWM30184.1 - 6.4e-64 216.2 0.0 8.4e-63 212.5 0.0 2.4 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Pex19 PF04614.12 EWM30185.1 - 3.2e-35 122.1 0.0 4.6e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Pex19 protein family SPX PF03105.19 EWM30185.1 - 0.0077 16.2 0.3 0.012 15.6 0.3 1.2 1 0 0 1 1 1 1 SPX domain HNF-1_N PF04814.13 EWM30185.1 - 0.18 12.4 0.9 0.27 11.8 0.9 1.2 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus DRIM PF07539.12 EWM30186.1 - 1.8e-56 191.7 0.0 7.6e-55 186.4 0.0 3.1 3 0 0 3 3 3 1 Down-regulated in metastasis HEAT PF02985.22 EWM30186.1 - 6.3e-06 26.0 4.9 0.0015 18.6 0.2 5.3 4 0 0 4 4 4 1 HEAT repeat Tti2 PF10521.9 EWM30186.1 - 0.011 15.3 0.0 0.17 11.4 0.0 2.8 2 0 0 2 2 2 0 Tti2 family Npa1 PF11707.8 EWM30186.1 - 0.087 12.2 0.9 0.33 10.3 0.9 2.0 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal HEAT_EZ PF13513.6 EWM30186.1 - 0.093 13.3 3.2 1.1 9.9 0.1 4.7 5 0 0 5 5 5 0 HEAT-like repeat HEAT_2 PF13646.6 EWM30186.1 - 0.83 10.1 10.8 1.7 9.1 0.1 5.9 7 0 0 7 7 7 0 HEAT repeats Patatin PF01734.22 EWM30187.1 - 5.5e-29 101.8 0.5 1.5e-28 100.4 0.0 2.1 2 0 0 2 2 2 1 Patatin-like phospholipase CIA30 PF08547.12 EWM30188.1 - 3.7e-28 98.6 0.0 4.7e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) 2OG-FeII_Oxy_3 PF13640.6 EWM30189.1 - 3.8e-09 37.3 0.0 7.3e-08 33.2 0.0 2.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily PT-VENN PF04829.13 EWM30189.1 - 0.75 9.9 2.7 1.7 8.8 2.7 1.6 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif RRM_1 PF00076.22 EWM30191.1 - 5.6e-06 26.1 0.0 9.6e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF525 PF04379.14 EWM30192.1 - 5.4e-09 36.2 0.1 1.3e-08 35.0 0.1 1.7 1 1 0 1 1 1 1 ApaG domain zf-CW PF07496.15 EWM30192.1 - 0.084 12.9 1.1 0.17 12.0 1.1 1.5 1 0 0 1 1 1 0 CW-type Zinc Finger SUIM_assoc PF16619.5 EWM30192.1 - 0.55 10.3 11.5 0.26 11.4 6.6 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Complex1_LYR PF05347.15 EWM30192.1 - 1.3 9.2 4.2 9.5 6.4 1.2 2.4 2 0 0 2 2 2 0 Complex 1 protein (LYR family) Asp_Arg_Hydrox PF05118.15 EWM30193.1 - 2.5e-39 134.6 0.0 3.3e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase DUF1241 PF06840.11 EWM30194.1 - 0.054 13.1 0.3 0.36 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1241) DUF4145 PF13643.6 EWM30194.1 - 0.06 13.5 0.0 0.082 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4145) Imm58 PF15581.6 EWM30194.1 - 0.082 13.0 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 58 DUF3489 PF11994.8 EWM30194.1 - 0.094 12.8 0.0 0.21 11.7 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3489) NAD_synthase PF02540.17 EWM30195.1 - 9.3e-07 28.2 0.0 0.00017 20.8 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Asn_synthase PF00733.21 EWM30195.1 - 2.6e-05 24.1 0.0 4.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.16 EWM30195.1 - 0.0014 17.5 0.0 0.057 12.2 0.0 2.2 2 0 0 2 2 2 2 tRNA methyl transferase NAP PF00956.18 EWM30196.1 - 5.3e-22 78.3 5.6 1.7e-18 66.8 0.8 2.9 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) Uds1 PF15456.6 EWM30196.1 - 0.045 13.9 1.4 0.077 13.2 1.4 1.4 1 0 0 1 1 1 0 Up-regulated During Septation NAP PF00956.18 EWM30197.1 - 4.8e-22 78.4 5.5 2.4e-18 66.3 0.6 2.8 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) Sacchrp_dh_C PF16653.5 EWM30198.1 - 0.055 13.6 0.1 1.5 8.9 0.0 2.1 1 1 0 2 2 2 0 Saccharopine dehydrogenase C-terminal domain Choline_kinase PF01633.20 EWM30199.1 - 1.3e-43 149.1 0.0 1.8e-43 148.6 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EWM30199.1 - 3.3e-17 63.2 0.0 2.5e-13 50.5 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Spb1_C PF07780.12 EWM30200.1 - 1e-54 185.4 14.4 1e-54 185.4 14.4 3.9 4 0 0 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.19 EWM30200.1 - 1e-51 175.5 0.0 1.9e-51 174.7 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 EWM30200.1 - 4.5e-40 137.1 3.9 4.5e-40 137.1 3.9 5.3 6 2 0 6 6 6 1 Domain of unknown function (DUF3381) DUF148 PF02520.17 EWM30200.1 - 0.0034 17.5 0.3 0.0034 17.5 0.3 2.1 2 0 0 2 2 2 1 Domain of unknown function DUF148 Methyltr_RsmB-F PF01189.17 EWM30200.1 - 0.24 11.0 1.8 0.66 9.6 0.1 2.3 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F DUF111 PF01969.17 EWM30201.1 - 9.1e-119 396.9 0.0 1.1e-118 396.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF111 DUF2964 PF11177.8 EWM30201.1 - 0.71 10.1 3.2 0.32 11.2 0.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2964) SelP_N PF04592.14 EWM30201.1 - 0.82 9.0 10.9 1.4 8.3 10.9 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CSN8_PSD8_EIF3K PF10075.9 EWM30203.1 - 1.6e-15 57.4 0.1 2.6e-15 56.6 0.1 1.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Mpv17_PMP22 PF04117.12 EWM30205.1 - 4.3e-05 23.6 0.0 8.1e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family FMN_dh PF01070.18 EWM30206.1 - 7.3e-142 472.5 0.7 8.3e-142 472.3 0.7 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.14 EWM30206.1 - 4.9e-05 22.8 0.7 0.019 14.3 0.1 2.6 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 EWM30206.1 - 0.00015 20.9 0.8 0.0021 17.1 0.2 2.6 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EWM30206.1 - 0.009 15.4 0.2 0.014 14.8 0.2 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase TMP-TENI PF02581.17 EWM30206.1 - 0.063 12.6 0.0 0.21 10.9 0.0 1.9 1 0 0 1 1 1 0 Thiamine monophosphate synthase Glu_synthase PF01645.17 EWM30206.1 - 0.07 12.2 0.2 0.15 11.2 0.1 1.5 2 0 0 2 2 2 0 Conserved region in glutamate synthase His_biosynth PF00977.21 EWM30206.1 - 0.11 11.9 0.0 1.1 8.7 0.0 2.1 1 1 1 2 2 2 0 Histidine biosynthesis protein DHO_dh PF01180.21 EWM30206.1 - 0.16 11.1 0.1 4.3 6.5 0.0 2.1 1 1 1 2 2 2 0 Dihydroorotate dehydrogenase PDT PF00800.18 EWM30208.1 - 6.7e-58 195.5 0.0 2.1e-56 190.6 0.0 2.7 3 0 0 3 3 3 1 Prephenate dehydratase PDH PF02153.17 EWM30208.1 - 3.6e-14 52.4 0.0 5.3e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 EWM30208.1 - 1.5e-08 35.1 0.0 3.3e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EWM30208.1 - 0.048 13.8 0.0 0.087 13.0 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.18 EWM30208.1 - 0.057 13.7 0.0 0.18 12.1 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Ephrin_lbd PF01404.19 EWM30208.1 - 0.23 11.5 0.1 0.42 10.6 0.1 1.3 1 0 0 1 1 1 0 Ephrin receptor ligand binding domain zf-C3HC4_2 PF13923.6 EWM30209.1 - 1.3e-09 37.8 7.6 1.3e-09 37.8 7.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EWM30209.1 - 1.1e-08 34.8 6.7 1.1e-08 34.8 6.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EWM30209.1 - 1.3e-08 34.9 6.1 1.3e-08 34.9 6.1 2.1 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 EWM30209.1 - 3e-06 27.5 7.7 3e-06 27.5 7.7 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EWM30209.1 - 7.2e-06 25.9 4.0 7.2e-06 25.9 4.0 1.9 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EWM30209.1 - 1.6e-05 24.8 15.7 9.5e-05 22.3 7.3 2.5 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EWM30209.1 - 2.3e-05 24.1 7.2 2.3e-05 24.1 7.2 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 EWM30209.1 - 4e-05 23.4 2.4 0.0001 22.1 2.4 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RanBP PF00641.18 EWM30209.1 - 0.0034 16.7 4.0 0.0034 16.7 4.0 2.5 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others SAP PF02037.27 EWM30209.1 - 0.0045 16.7 0.0 0.0097 15.6 0.0 1.5 1 0 0 1 1 1 1 SAP domain zf-rbx1 PF12678.7 EWM30209.1 - 0.026 14.8 9.1 0.026 14.8 9.1 2.5 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EWM30209.1 - 0.028 14.4 1.9 0.028 14.4 1.9 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Ribosomal_L21p PF00829.21 EWM30209.1 - 0.074 13.3 3.0 0.43 10.8 2.5 2.4 1 1 1 2 2 2 0 Ribosomal prokaryotic L21 protein Prok-RING_4 PF14447.6 EWM30209.1 - 0.21 11.5 16.0 0.051 13.4 8.2 3.0 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 EWM30209.1 - 0.91 9.7 10.9 0.19 11.9 4.0 2.6 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-C3HC4_5 PF17121.5 EWM30209.1 - 2.7 7.9 6.4 11 6.0 6.0 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Cation_ATPase_C PF00689.21 EWM30210.1 - 5.7e-42 143.5 2.8 5.7e-42 143.5 2.8 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EWM30210.1 - 1.1e-32 113.0 6.0 1.3e-32 112.7 0.1 3.1 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 EWM30210.1 - 3.7e-15 55.4 0.0 9.5e-15 54.1 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EWM30210.1 - 4.6e-13 49.1 0.0 9.3e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EWM30210.1 - 4.7e-12 46.6 3.5 3.7e-09 37.2 0.1 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EWM30210.1 - 0.0042 16.9 0.9 0.072 12.8 0.6 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase UDPGP PF01704.18 EWM30211.1 - 2.4e-17 62.7 0.0 5.8e-17 61.4 0.0 1.4 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Ham1p_like PF01725.16 EWM30212.1 - 1.9e-43 148.6 0.0 2.4e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 Ham1 family NOC3p PF07540.11 EWM30213.1 - 1.6e-22 79.8 0.0 5.5e-22 78.0 0.0 2.0 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.17 EWM30213.1 - 3.2e-14 53.3 7.1 3.4e-14 53.2 0.0 3.4 4 0 0 4 4 4 1 CBF/Mak21 family Nucleo_P87 PF07267.11 EWM30213.1 - 0.28 10.0 7.1 0.55 9.0 7.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 BSP_II PF05432.11 EWM30213.1 - 1.9 8.1 23.8 0.14 11.9 17.3 2.1 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) FAM176 PF14851.6 EWM30213.1 - 4.8 6.8 16.3 1.4 8.5 8.5 2.7 2 0 0 2 2 2 0 FAM176 family Eapp_C PF10238.9 EWM30213.1 - 4.9 7.2 13.0 21 5.2 6.6 2.6 2 0 0 2 2 2 0 E2F-associated phosphoprotein RPN2_C PF18004.1 EWM30213.1 - 5 7.0 19.4 1 9.3 12.8 2.4 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain PPR_2 PF13041.6 EWM30215.1 - 3.7e-54 180.7 0.0 7e-09 35.7 0.0 12.4 9 3 4 13 13 13 10 PPR repeat family PPR PF01535.20 EWM30215.1 - 1.5e-38 128.3 20.1 0.00037 20.5 0.0 16.0 18 0 0 18 18 18 8 PPR repeat PPR_3 PF13812.6 EWM30215.1 - 6.3e-34 115.9 0.0 1e-06 28.7 0.0 11.0 7 2 6 13 13 13 4 Pentatricopeptide repeat domain PPR_long PF17177.4 EWM30215.1 - 1.8e-25 89.6 1.3 1.9e-10 40.5 0.2 7.0 3 2 4 7 7 7 6 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EWM30215.1 - 1.1e-17 63.4 1.1 0.12 12.1 0.0 9.3 10 0 0 10 10 10 5 PPR repeat HrpB1_HrpK PF09613.10 EWM30215.1 - 0.0051 16.4 1.6 3 7.5 0.0 4.1 3 1 0 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) ANAPC3 PF12895.7 EWM30215.1 - 0.0096 16.1 4.7 9 6.6 0.2 5.1 4 2 1 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 HRDC PF00570.23 EWM30215.1 - 0.016 15.2 0.7 0.88 9.6 0.1 3.3 4 0 0 4 4 4 0 HRDC domain YfiO PF13525.6 EWM30215.1 - 0.18 11.5 3.3 1.6 8.4 0.0 3.7 5 0 0 5 5 5 0 Outer membrane lipoprotein Kinesin PF00225.23 EWM30216.1 - 1.3e-108 362.8 0.0 3.3e-108 361.6 0.0 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EWM30216.1 - 1.3e-23 83.5 0.0 4.2e-23 81.9 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding Microtub_bind PF13931.6 EWM30216.1 - 2.9e-05 24.5 0.2 2.9e-05 24.5 0.2 4.5 3 2 1 4 4 4 1 Kinesin-associated microtubule-binding Fes1 PF08609.10 EWM30216.1 - 0.94 10.4 8.5 0.46 11.4 1.6 4.0 3 1 0 3 3 3 0 Nucleotide exchange factor Fes1 IFT57 PF10498.9 EWM30216.1 - 1.1 8.2 18.1 0.02 13.8 9.6 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 BORCS7 PF16088.5 EWM30216.1 - 1.9 8.8 7.8 8.8 6.7 2.1 4.0 3 0 0 3 3 3 0 BLOC-1-related complex sub-unit 7 PKcGMP_CC PF16808.5 EWM30216.1 - 3.4 7.6 8.2 2.9 7.8 5.6 2.3 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase RAP PF08373.10 EWM30218.1 - 6.8e-14 51.7 0.0 1.3e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 RAP domain FAST_1 PF06743.15 EWM30218.1 - 0.0029 17.5 0.0 0.049 13.6 0.0 2.9 3 1 0 3 3 3 1 FAST kinase-like protein, subdomain 1 CRAL_TRIO PF00650.20 EWM30219.1 - 2.3e-20 72.9 0.0 4.8e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain PH PF00169.29 EWM30219.1 - 8.2e-09 35.9 0.0 1.9e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF2436 PF10365.9 EWM30219.1 - 0.019 14.7 0.0 0.057 13.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF2436) CRAL_TRIO_2 PF13716.6 EWM30219.1 - 0.026 14.7 0.1 0.051 13.7 0.1 1.5 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Ribosomal_L13 PF00572.18 EWM30220.1 - 7e-09 36.0 0.0 3.5e-07 30.5 0.0 2.5 2 1 0 2 2 2 1 Ribosomal protein L13 Pkinase PF00069.25 EWM30221.1 - 3.8e-65 219.9 0.0 5e-65 219.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM30221.1 - 1.2e-42 146.0 0.0 1.8e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EWM30221.1 - 4.9e-27 94.1 2.9 2.6e-14 53.3 0.0 2.6 2 0 0 2 2 2 2 P21-Rho-binding domain Kinase-like PF14531.6 EWM30221.1 - 5.5e-06 25.9 0.7 0.00095 18.6 0.0 2.8 2 1 1 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 EWM30221.1 - 0.00033 19.5 0.0 0.00048 19.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EWM30221.1 - 0.0044 16.0 0.0 0.0088 15.0 0.0 1.5 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EWM30221.1 - 0.0059 16.5 1.6 0.056 13.3 0.0 2.7 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 EWM30221.1 - 0.031 13.6 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EWM30221.1 - 0.036 13.1 0.0 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 CRAL_TRIO PF00650.20 EWM30222.1 - 4.6e-32 110.9 0.0 5.9e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EWM30222.1 - 4.8e-05 23.5 0.0 6.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Clat_adaptor_s PF01217.20 EWM30223.1 - 1.5e-41 141.6 5.1 8.7e-40 135.9 5.1 2.0 1 1 0 1 1 1 1 Clathrin adaptor complex small chain HOCHOB PF17943.1 EWM30223.1 - 0.036 14.8 0.1 0.11 13.3 0.0 1.9 2 0 0 2 2 2 0 Homeobox-cysteine loop-homeobox PseudoU_synth_1 PF01416.20 EWM30224.1 - 2.5e-22 79.4 0.0 1.4e-14 54.4 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase ORMDL PF04061.14 EWM30225.1 - 5.6e-36 123.4 3.2 6.5e-36 123.1 3.2 1.0 1 0 0 1 1 1 1 ORMDL family Acyl_transf_3 PF01757.22 EWM30225.1 - 0.099 11.7 8.3 0.16 11.0 8.4 1.5 1 1 0 1 1 1 0 Acyltransferase family Radical_SAM_C PF16199.5 EWM30226.1 - 1.2e-32 111.7 0.0 2.7e-32 110.6 0.0 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 EWM30226.1 - 5.3e-19 69.2 0.1 6.4e-18 65.7 0.1 2.4 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 EWM30226.1 - 1.7e-09 37.9 0.1 3.7e-09 36.8 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EWM30226.1 - 1.2e-06 28.5 0.1 2.9e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EWM30226.1 - 0.00076 19.9 0.2 0.0016 18.8 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EWM30226.1 - 0.047 13.7 0.0 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 FR47-like protein Rep_2 PF01719.17 EWM30226.1 - 0.093 12.5 0.0 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 Plasmid replication protein Peptidase_M16 PF00675.20 EWM30228.1 - 7e-19 68.3 0.0 1.3e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EWM30228.1 - 0.05 13.6 0.0 0.28 11.2 0.0 2.1 3 0 0 3 3 3 0 Peptidase M16 inactive domain Amino_oxidase PF01593.24 EWM30229.1 - 3e-13 49.9 0.0 7.4e-13 48.6 0.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EWM30229.1 - 2e-07 31.1 0.2 4.7e-07 29.9 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EWM30229.1 - 1.7e-05 24.3 0.8 2.6e-05 23.6 0.8 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EWM30229.1 - 0.0016 17.7 0.1 0.0028 16.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 EWM30229.1 - 0.0031 16.6 0.1 0.0051 16.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EWM30229.1 - 0.0065 15.7 0.0 0.02 14.1 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EWM30229.1 - 0.016 14.8 0.0 0.039 13.5 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 EWM30229.1 - 0.034 13.4 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 EWM30229.1 - 0.18 12.4 0.1 0.48 11.0 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ELO PF01151.18 EWM30230.1 - 3.5e-58 197.1 19.2 4.6e-58 196.7 19.2 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family SLATT_4 PF18186.1 EWM30230.1 - 0.039 13.6 0.1 0.069 12.8 0.1 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 RNA_pol_Rpb2_6 PF00562.28 EWM30232.1 - 3.7e-118 395.0 0.0 5.3e-118 394.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EWM30232.1 - 4.2e-50 170.1 0.0 6.2e-50 169.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 EWM30232.1 - 1.5e-32 111.8 0.2 3.8e-32 110.5 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 EWM30232.1 - 5.4e-22 78.4 0.0 1.6e-21 76.8 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 EWM30232.1 - 2.6e-21 75.6 0.0 4.9e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 EWM30232.1 - 3e-21 75.5 0.4 6.7e-21 74.3 0.4 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 EWM30232.1 - 1.6e-08 35.0 1.5 6.1e-08 33.1 1.5 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Viral_env_E26 PF11050.8 EWM30232.1 - 0.021 14.2 0.2 0.044 13.2 0.2 1.5 1 0 0 1 1 1 0 Virus envelope protein E26 Peptidase_M41 PF01434.18 EWM30233.1 - 4.6e-63 212.5 0.0 8.9e-63 211.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EWM30233.1 - 1.8e-44 151.4 0.1 9.8e-44 149.0 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EWM30233.1 - 6.6e-10 38.6 0.0 1.8e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 EWM30233.1 - 7.8e-07 29.4 0.0 3.7e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 FtsH Extracellular AAA_5 PF07728.14 EWM30233.1 - 0.00083 19.4 0.1 0.014 15.3 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EWM30233.1 - 0.002 17.9 0.0 0.0086 15.8 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EWM30233.1 - 0.0023 17.2 0.1 0.0044 16.3 0.1 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 EWM30233.1 - 0.004 17.6 0.2 0.13 12.7 0.1 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 EWM30233.1 - 0.0046 17.1 0.0 0.014 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EWM30233.1 - 0.0069 16.7 0.0 0.21 11.8 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EWM30233.1 - 0.0072 16.7 0.0 0.019 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EWM30233.1 - 0.028 14.7 0.0 0.074 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EWM30233.1 - 0.036 14.1 0.0 0.44 10.5 0.0 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EWM30233.1 - 0.075 13.2 0.1 0.19 11.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain TraF_2 PF13729.6 EWM30233.1 - 0.077 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein Mg_chelatase PF01078.21 EWM30233.1 - 0.09 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EWM30233.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 EWM30233.1 - 0.12 12.4 0.0 0.45 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 EWM30234.1 - 5.4e-18 65.4 0.0 1.1e-17 64.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EWM30234.1 - 1.2e-15 57.8 0.0 3.5e-15 56.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HRDC PF00570.23 EWM30234.1 - 5e-10 39.2 0.1 1.3e-09 37.9 0.1 1.8 1 0 0 1 1 1 1 HRDC domain RecQ_Zn_bind PF16124.5 EWM30234.1 - 8e-08 32.9 0.5 2.8e-07 31.1 0.5 2.0 1 0 0 1 1 1 1 RecQ zinc-binding HTH_40 PF14493.6 EWM30234.1 - 9e-08 32.5 0.0 2.3e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain RQC PF09382.10 EWM30234.1 - 3.2e-06 26.9 0.0 7.8e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 RQC domain ResIII PF04851.15 EWM30234.1 - 0.068 13.2 0.0 0.3 11.0 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PPR_2 PF13041.6 EWM30236.1 - 9.5e-68 224.2 0.0 4.9e-11 42.6 0.0 18.9 13 3 7 20 20 20 10 PPR repeat family PPR PF01535.20 EWM30236.1 - 1.4e-65 213.0 34.9 5.4e-06 26.3 0.0 21.4 22 0 0 22 22 22 17 PPR repeat PPR_3 PF13812.6 EWM30236.1 - 3.2e-41 139.2 0.0 1.1e-08 35.1 0.0 10.7 8 3 2 12 12 12 8 Pentatricopeptide repeat domain PPR_long PF17177.4 EWM30236.1 - 9.1e-30 103.6 1.1 1.7e-10 40.7 0.0 7.2 3 2 3 6 6 6 6 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EWM30236.1 - 4.6e-28 96.6 5.2 8.5e-06 25.4 0.0 15.0 16 1 0 16 16 16 4 PPR repeat ANAPC3 PF12895.7 EWM30236.1 - 1.1e-07 31.9 20.3 1.4 9.2 0.2 9.7 10 4 5 15 15 13 4 Anaphase-promoting complex, cyclosome, subunit 3 HrpB1_HrpK PF09613.10 EWM30236.1 - 3.7e-05 23.4 25.3 0.21 11.2 0.4 9.7 6 4 5 11 11 10 2 Bacterial type III secretion protein (HrpB1_HrpK) TPR_12 PF13424.6 EWM30236.1 - 5.6e-05 23.4 21.4 2.5 8.5 0.4 10.5 8 3 2 10 10 10 1 Tetratricopeptide repeat TPR_7 PF13176.6 EWM30236.1 - 0.00098 19.0 11.9 38 4.6 0.1 9.0 11 0 0 11 11 10 0 Tetratricopeptide repeat TPR_14 PF13428.6 EWM30236.1 - 0.0015 19.2 35.9 21 6.2 0.1 13.3 12 4 4 16 16 15 0 Tetratricopeptide repeat COX5A PF02284.16 EWM30236.1 - 0.0072 16.3 0.5 5.2 7.1 0.0 4.9 5 0 0 5 5 5 1 Cytochrome c oxidase subunit Va MRP-S27 PF10037.9 EWM30236.1 - 0.015 14.2 1.2 0.73 8.6 0.0 3.6 4 1 1 5 5 5 0 Mitochondrial 28S ribosomal protein S27 TPR_2 PF07719.17 EWM30236.1 - 0.1 12.8 16.4 17 5.8 0.1 9.8 12 1 0 12 12 11 0 Tetratricopeptide repeat TPR_4 PF07721.14 EWM30236.1 - 1.4 9.7 39.0 0.58 10.9 2.5 9.9 10 0 0 10 10 9 0 Tetratricopeptide repeat BTAD PF03704.17 EWM30236.1 - 1.8 9.0 28.8 0.31 11.5 0.2 6.8 6 1 1 7 7 7 0 Bacterial transcriptional activator domain TPR_6 PF13174.6 EWM30236.1 - 2.3 9.0 18.0 35 5.3 0.0 9.0 13 0 0 13 13 10 0 Tetratricopeptide repeat PPR_2 PF13041.6 EWM30237.1 - 5e-93 305.2 16.9 1.6e-12 47.4 0.1 12.8 6 2 7 13 13 13 11 PPR repeat family PPR PF01535.20 EWM30237.1 - 4.6e-90 289.8 4.5 7.5e-07 29.0 0.0 15.3 15 0 0 15 15 15 12 PPR repeat PPR_3 PF13812.6 EWM30237.1 - 4.6e-90 295.7 0.1 2.6e-13 49.9 0.1 9.5 7 3 4 11 11 10 10 Pentatricopeptide repeat domain PPR_1 PF12854.7 EWM30237.1 - 4.6e-89 291.8 0.0 3.7e-08 32.9 0.0 14.9 15 0 0 15 15 14 13 PPR repeat PPR_long PF17177.4 EWM30237.1 - 5.3e-40 137.0 0.0 6.9e-11 41.9 0.0 5.7 1 1 4 5 5 5 5 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 EWM30237.1 - 2.1e-16 59.2 4.8 3.1 8.9 0.0 11.3 10 2 2 12 12 10 2 Tetratricopeptide repeat Wzy_C_2 PF11846.8 EWM30237.1 - 1.1e-11 45.0 1.4 0.32 10.9 0.0 9.3 5 2 5 11 11 11 1 Virulence factor membrane-bound polymerase, C-terminal TPR_16 PF13432.6 EWM30237.1 - 6.9e-10 39.4 0.2 4.3 8.1 0.0 7.5 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_4 PF07721.14 EWM30237.1 - 1.8e-09 37.3 0.7 11 7.0 0.0 8.8 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_7 PF13176.6 EWM30237.1 - 1.5e-08 34.1 5.7 4.6 7.5 0.0 8.4 8 1 1 9 9 8 1 Tetratricopeptide repeat TPR_19 PF14559.6 EWM30237.1 - 3.6e-08 33.8 0.0 6.2 7.4 0.0 7.3 7 1 0 7 7 7 1 Tetratricopeptide repeat Clathrin PF00637.20 EWM30237.1 - 2.1e-06 27.7 0.0 0.14 12.0 0.0 5.1 4 1 2 6 6 6 1 Region in Clathrin and VPS HrpB1_HrpK PF09613.10 EWM30237.1 - 4.6e-06 26.3 0.3 0.0044 16.6 0.0 4.0 2 1 2 5 5 5 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_10 PF13374.6 EWM30237.1 - 8.7e-05 22.3 14.9 5.9 6.9 0.1 7.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_2 PF07719.17 EWM30237.1 - 0.00052 19.9 12.1 46 4.5 0.0 8.5 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_12 PF13424.6 EWM30237.1 - 0.00068 19.9 7.1 43 4.5 0.0 6.4 7 1 0 7 7 5 0 Tetratricopeptide repeat TPR_15 PF13429.6 EWM30237.1 - 0.00077 18.8 0.0 21 4.2 0.0 4.5 3 1 2 5 5 5 0 Tetratricopeptide repeat ECSIT PF06239.11 EWM30237.1 - 0.00096 18.3 0.0 10 5.2 0.0 4.8 3 2 0 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway DUF4177 PF13783.6 EWM30237.1 - 0.0035 17.6 0.1 80 3.6 0.0 6.2 6 1 1 7 7 7 0 Domain of unknown function (DUF4177) Ank_5 PF13857.6 EWM30237.1 - 0.039 14.3 0.8 23 5.4 0.0 5.3 6 1 0 6 6 6 0 Ankyrin repeats (many copies) IgG_binding_B PF01378.17 EWM30237.1 - 0.14 12.3 0.2 1.1 9.4 0.0 2.6 3 0 0 3 3 3 0 B domain TPR_6 PF13174.6 EWM30237.1 - 1.5 9.6 4.8 1.2e+02 3.6 0.1 5.7 7 1 0 7 7 5 0 Tetratricopeptide repeat PPR_2 PF13041.6 EWM30238.1 - 1.8e-93 306.6 16.8 1.5e-12 47.5 0.1 12.8 6 2 7 13 13 13 11 PPR repeat family PPR PF01535.20 EWM30238.1 - 2.2e-90 290.8 4.5 7.2e-07 29.0 0.0 15.3 15 0 0 15 15 15 12 PPR repeat PPR_3 PF13812.6 EWM30238.1 - 3e-90 296.3 0.1 2.4e-13 49.9 0.1 9.5 7 3 4 11 11 11 10 Pentatricopeptide repeat domain PPR_1 PF12854.7 EWM30238.1 - 2.4e-89 292.6 0.0 3.5e-08 33.0 0.0 14.9 15 0 0 15 15 14 13 PPR repeat PPR_long PF17177.4 EWM30238.1 - 4e-40 137.5 0.0 7.3e-11 41.8 0.0 5.7 1 1 5 6 6 6 5 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 EWM30238.1 - 1.3e-16 59.9 4.9 2.9 8.9 0.0 11.4 10 2 2 12 12 10 2 Tetratricopeptide repeat Wzy_C_2 PF11846.8 EWM30238.1 - 8e-12 45.5 1.5 0.31 10.9 0.0 9.4 5 2 5 11 11 11 1 Virulence factor membrane-bound polymerase, C-terminal TPR_16 PF13432.6 EWM30238.1 - 4.8e-10 39.9 0.2 4.1 8.1 0.0 7.6 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_4 PF07721.14 EWM30238.1 - 1.2e-09 37.8 0.7 10 7.1 0.0 8.8 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_7 PF13176.6 EWM30238.1 - 9.4e-09 34.7 5.6 4.4 7.6 0.0 8.5 8 1 1 9 9 8 1 Tetratricopeptide repeat TPR_19 PF14559.6 EWM30238.1 - 2.6e-08 34.3 0.0 5.9 7.5 0.0 7.4 7 1 0 8 8 7 1 Tetratricopeptide repeat Clathrin PF00637.20 EWM30238.1 - 1.7e-06 28.0 0.0 0.13 12.1 0.0 5.1 4 1 2 6 6 6 1 Region in Clathrin and VPS HrpB1_HrpK PF09613.10 EWM30238.1 - 3.8e-06 26.6 0.3 0.0043 16.7 0.0 4.0 2 1 2 5 5 5 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_10 PF13374.6 EWM30238.1 - 6.2e-05 22.7 14.9 5.6 7.0 0.1 7.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_2 PF07719.17 EWM30238.1 - 0.00036 20.4 12.1 43 4.6 0.0 8.6 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_15 PF13429.6 EWM30238.1 - 0.00062 19.1 0.0 19 4.3 0.0 4.5 3 1 2 5 5 5 0 Tetratricopeptide repeat ECSIT PF06239.11 EWM30238.1 - 0.00078 18.6 0.0 10 5.2 0.0 4.9 3 2 0 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway TPR_12 PF13424.6 EWM30238.1 - 0.00098 19.4 8.1 41 4.5 0.0 6.4 7 1 0 7 7 5 0 Tetratricopeptide repeat DUF4177 PF13783.6 EWM30238.1 - 0.0028 17.9 0.2 76 3.7 0.0 6.2 7 1 1 8 8 7 0 Domain of unknown function (DUF4177) Ank_5 PF13857.6 EWM30238.1 - 0.031 14.6 0.8 22 5.5 0.0 5.4 6 1 0 6 6 6 0 Ankyrin repeats (many copies) IgG_binding_B PF01378.17 EWM30238.1 - 0.13 12.4 0.2 1 9.4 0.0 2.6 3 0 0 3 3 3 0 B domain TPR_6 PF13174.6 EWM30238.1 - 1.2 9.9 4.8 1.2e+02 3.7 0.1 5.8 7 1 0 7 7 5 0 Tetratricopeptide repeat SNF2_N PF00176.23 EWM30239.1 - 1.3e-57 195.2 0.0 2.1e-57 194.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EWM30239.1 - 7.3e-19 68.2 0.0 2e-18 66.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 EWM30239.1 - 3.3e-10 39.6 0.1 5.7e-10 38.8 0.1 1.2 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF1086 PF06461.11 EWM30239.1 - 9.3e-06 25.5 0.0 3.2e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 Domain of Unknown Function (DUF1086) DUF1087 PF06465.13 EWM30239.1 - 8.8e-05 22.5 0.8 8.8e-05 22.5 0.8 2.3 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1087) CHDCT2 PF08074.11 EWM30239.1 - 0.00064 19.9 3.4 0.58 10.3 0.0 3.5 3 0 0 3 3 3 2 CHDCT2 (NUC038) domain FERM_M PF00373.18 EWM30239.1 - 0.14 12.5 0.1 26 5.3 0.0 2.5 2 0 0 2 2 2 0 FERM central domain SGT1 PF07093.11 EWM30240.1 - 1.7e-80 271.1 0.0 1e-45 156.3 0.0 3.0 3 0 0 3 3 3 3 SGT1 protein GAF PF01590.26 EWM30241.1 - 1.1e-07 32.5 2.4 0.3 11.7 0.0 6.6 7 0 0 7 7 7 2 GAF domain DUF3853 PF12964.7 EWM30241.1 - 0.067 13.4 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3853) Gln-synt_C PF00120.24 EWM30243.1 - 3.4e-67 226.9 0.0 2.9e-65 220.6 0.0 2.5 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain FAST_1 PF06743.15 EWM30244.1 - 4e-07 29.9 0.5 11 6.0 0.0 7.3 5 2 2 7 7 7 3 FAST kinase-like protein, subdomain 1 RAP PF08373.10 EWM30244.1 - 1.6e-05 24.9 0.0 5.4e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 RAP domain Aldo_ket_red PF00248.21 EWM30245.1 - 0.00028 20.2 0.0 0.00048 19.4 0.0 1.4 1 0 0 1 1 1 1 Aldo/keto reductase family PQ-loop PF04193.14 EWM30246.1 - 3e-31 106.9 13.3 4.4e-17 61.6 6.6 3.5 2 1 1 3 3 3 2 PQ loop repeat CitMHS PF03600.16 EWM30246.1 - 0.033 13.4 3.5 0.05 12.8 3.5 1.3 1 0 0 1 1 1 0 Citrate transporter DUF4190 PF13828.6 EWM30246.1 - 0.14 11.9 0.2 0.14 11.9 0.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4190) CaKB PF03185.15 EWM30246.1 - 0.61 9.7 2.6 1.2 8.7 1.6 2.0 1 1 1 2 2 2 0 Calcium-activated potassium channel, beta subunit DUF4705 PF15788.5 EWM30247.1 - 0.0015 18.8 2.0 0.0048 17.1 2.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4705) MMR_HSR1 PF01926.23 EWM30248.1 - 8e-22 77.5 0.0 1.5e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase KH_2 PF07650.17 EWM30248.1 - 2.3e-16 59.4 0.0 3.6e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 KH domain GTP_EFTU PF00009.27 EWM30248.1 - 2.4e-08 33.8 0.0 7.1e-06 25.7 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EWM30248.1 - 3.4e-07 29.9 0.0 7.6e-07 28.8 0.0 1.5 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EWM30248.1 - 7.6e-07 29.3 1.0 0.00081 19.5 0.6 2.3 1 1 1 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 EWM30248.1 - 3.2e-05 23.9 0.1 0.0012 18.8 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 EWM30248.1 - 9e-05 21.9 0.0 0.00045 19.6 0.0 1.9 2 0 0 2 2 2 1 AIG1 family Roc PF08477.13 EWM30248.1 - 0.0079 16.4 0.0 0.022 15.0 0.0 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 EWM30248.1 - 0.013 15.3 0.2 0.5 10.1 0.1 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Ras PF00071.22 EWM30248.1 - 0.015 14.9 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 Ras family SRPRB PF09439.10 EWM30248.1 - 0.065 12.7 0.0 0.17 11.3 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Ploopntkinase3 PF18751.1 EWM30248.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_22 PF13401.6 EWM30248.1 - 0.14 12.5 0.0 0.3 11.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain Rad4 PF03835.15 EWM30249.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Rad4 transglutaminase-like domain Cyto_heme_lyase PF01265.17 EWM30250.1 - 4.4e-61 207.0 0.3 7.1e-61 206.4 0.3 1.3 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase PWI PF01480.17 EWM30252.1 - 8.3e-13 48.5 0.3 1.8e-12 47.4 0.3 1.5 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 EWM30252.1 - 6e-09 35.6 0.0 1.1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC2_membrane PF01061.24 EWM30253.1 - 2.4e-39 134.9 11.4 3.3e-39 134.5 11.4 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EWM30253.1 - 8.2e-20 71.7 0.0 1.4e-19 70.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EWM30253.1 - 4.8e-05 22.6 5.8 4.8e-05 22.6 5.8 1.9 1 1 1 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 EWM30253.1 - 6.3e-05 22.9 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EWM30253.1 - 0.00044 19.9 0.1 0.0013 18.4 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EWM30253.1 - 0.0029 17.1 0.0 0.71 9.3 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 EWM30253.1 - 0.0042 16.7 0.0 0.009 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EWM30253.1 - 0.0071 16.8 0.1 0.019 15.4 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 EWM30253.1 - 0.025 14.9 0.2 0.12 12.7 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 EWM30253.1 - 0.06 13.6 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain CcmB PF03379.13 EWM30253.1 - 0.11 12.0 0.7 0.18 11.3 0.7 1.3 1 0 0 1 1 1 0 CcmB protein Ribosomal_S6e PF01092.19 EWM30253.1 - 0.13 12.2 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein S6e AAA_33 PF13671.6 EWM30253.1 - 0.13 12.4 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Prenyltransf PF01255.19 EWM30254.1 - 0.0073 15.8 0.1 0.013 15.0 0.1 1.4 2 0 0 2 2 2 1 Putative undecaprenyl diphosphate synthase GPS PF01825.21 EWM30254.1 - 0.099 13.2 0.1 0.23 12.0 0.1 1.6 1 0 0 1 1 1 0 GPCR proteolysis site, GPS, motif Fumerase_C PF05683.12 EWM30255.1 - 1.2e-86 289.3 0.0 2e-86 288.5 0.0 1.4 1 0 0 1 1 1 1 Fumarase C-terminus Fumerase PF05681.14 EWM30255.1 - 3.2e-85 285.8 0.0 4.8e-85 285.2 0.0 1.2 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) DUF2183 PF09949.9 EWM30256.1 - 0.00057 20.2 0.0 0.0011 19.2 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Sulfotransfer_2 PF03567.14 EWM30257.1 - 1.6e-05 25.0 0.1 0.0003 20.8 0.1 2.2 1 1 0 1 1 1 1 Sulfotransferase family AAA PF00004.29 EWM30258.1 - 4.3e-40 137.2 0.1 1.4e-39 135.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EWM30258.1 - 5e-19 68.0 0.2 1.1e-18 66.9 0.2 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EWM30258.1 - 1.9e-12 46.8 0.7 5.1e-12 45.4 0.7 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EWM30258.1 - 4.8e-08 33.1 0.2 2.9e-07 30.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EWM30258.1 - 8.2e-08 32.6 0.0 2.5e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 EWM30258.1 - 7.8e-05 22.5 0.6 0.0013 18.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EWM30258.1 - 8.9e-05 22.9 1.1 0.00072 20.0 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 EWM30258.1 - 0.00022 21.0 0.0 0.00077 19.2 0.1 2.0 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EWM30258.1 - 0.00052 20.3 0.1 0.01 16.1 0.0 2.4 1 1 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EWM30258.1 - 0.0021 18.0 0.0 1.5 8.7 0.0 2.7 1 1 1 2 2 2 2 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 EWM30258.1 - 0.0022 17.4 0.1 0.0045 16.4 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EWM30258.1 - 0.0028 17.2 0.0 0.0063 16.1 0.0 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_33 PF13671.6 EWM30258.1 - 0.0038 17.4 0.3 0.0087 16.2 0.0 1.9 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EWM30258.1 - 0.016 14.9 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 EWM30258.1 - 0.016 15.7 1.4 0.066 13.8 0.0 2.8 2 2 1 3 3 3 0 AAA domain AAA_14 PF13173.6 EWM30258.1 - 0.019 15.0 0.1 0.087 12.9 0.0 2.2 2 1 1 3 3 2 0 AAA domain Sigma54_activat PF00158.26 EWM30258.1 - 0.035 13.8 0.1 0.17 11.6 0.1 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.13 EWM30258.1 - 0.04 13.1 0.0 0.083 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 EWM30258.1 - 0.05 13.2 0.9 0.28 10.7 0.1 2.4 2 1 1 3 3 3 0 AAA domain Parvo_NS1 PF01057.17 EWM30258.1 - 0.079 12.0 0.1 0.29 10.2 0.0 1.9 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 EWM30258.1 - 0.11 12.4 0.2 0.3 11.0 0.1 1.8 2 0 0 2 2 1 0 NACHT domain ATPase PF06745.13 EWM30258.1 - 0.14 11.4 2.1 0.8 9.0 0.0 2.5 2 0 0 2 2 2 0 KaiC TsaE PF02367.17 EWM30258.1 - 0.15 12.1 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EWM30258.1 - 0.16 12.4 0.0 0.36 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.6 EWM30258.1 - 0.21 11.3 2.0 1 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF1192 PF06698.11 EWM30258.1 - 0.26 11.4 4.3 0.69 10.0 4.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) GrpE PF01025.19 EWM30258.1 - 0.89 9.2 6.4 1 9.0 4.8 1.9 2 0 0 2 2 2 0 GrpE Med8 PF10232.9 EWM30258.1 - 5.3 6.6 6.2 1.6 8.2 1.7 2.0 1 1 1 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 RRM_1 PF00076.22 EWM30260.1 - 9.3e-31 105.5 0.0 2.1e-15 56.3 0.0 4.3 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EWM30260.1 - 0.029 14.0 0.0 0.087 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EWM30260.1 - 0.06 13.4 0.1 0.35 11.0 0.0 2.3 2 0 0 2 2 2 0 Limkain b1 zf-RING_11 PF17123.5 EWM30260.1 - 0.14 11.9 0.3 0.35 10.6 0.3 1.7 1 0 0 1 1 1 0 RING-like zinc finger HSP90 PF00183.18 EWM30260.1 - 0.28 10.0 4.4 0.4 9.5 4.4 1.1 1 0 0 1 1 1 0 Hsp90 protein Presenilin PF01080.17 EWM30260.1 - 3.2 6.4 6.3 5 5.8 6.3 1.2 1 0 0 1 1 1 0 Presenilin IMPDH PF00478.25 EWM30261.1 - 7.6e-129 429.6 7.4 9.3e-129 429.3 7.4 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 EWM30261.1 - 3.8e-13 49.7 0.6 1.4e-05 25.5 0.1 3.0 2 1 0 2 2 2 2 CBS domain NMO PF03060.15 EWM30261.1 - 6.2e-08 32.4 3.5 3.3e-06 26.7 2.6 2.3 2 0 0 2 2 2 1 Nitronate monooxygenase FMN_dh PF01070.18 EWM30261.1 - 8.3e-07 28.4 1.6 1.5e-06 27.5 1.6 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 EWM30261.1 - 0.0014 18.1 6.6 0.003 17.0 2.7 2.8 3 1 0 3 3 3 1 Histidine biosynthesis protein ThiG PF05690.14 EWM30261.1 - 0.0015 17.9 0.6 0.0015 17.9 0.6 2.7 2 1 1 3 3 3 1 Thiazole biosynthesis protein ThiG NanE PF04131.14 EWM30261.1 - 0.0037 16.5 1.0 0.013 14.7 1.0 2.0 1 1 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase Aldolase PF01081.19 EWM30261.1 - 0.021 14.2 0.8 0.052 13.0 0.1 2.0 2 0 0 2 2 2 0 KDPG and KHG aldolase DUF561 PF04481.12 EWM30261.1 - 0.044 12.9 2.0 0.99 8.5 0.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF561) IceA2 PF05862.11 EWM30261.1 - 0.12 12.3 0.7 1.9 8.5 0.1 2.8 2 0 0 2 2 2 0 Helicobacter pylori IceA2 protein DHO_dh PF01180.21 EWM30261.1 - 0.21 10.8 5.1 1.1 8.4 1.0 2.5 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase AA_permease_2 PF13520.6 EWM30262.1 - 3.6e-32 111.7 31.2 7.6e-32 110.7 31.2 1.5 1 1 0 1 1 1 1 Amino acid permease DUF4281 PF14108.6 EWM30263.1 - 7e-33 113.7 4.2 1.3e-32 112.9 4.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4281) DivIVA PF05103.13 EWM30263.1 - 0.083 13.0 20.8 2.1 8.4 8.9 2.8 2 1 1 3 3 3 0 DivIVA protein V-ATPase_G_2 PF16999.5 EWM30263.1 - 0.28 11.6 22.8 0.81 10.1 9.2 2.8 2 1 1 3 3 3 0 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 EWM30263.1 - 3.3 7.8 27.5 1.1 9.3 23.2 2.4 2 1 1 3 3 3 0 ATP synthase B/B' CF(0) HrpE PF06188.12 EWM30263.1 - 5.3 6.9 13.2 10 5.9 7.0 2.4 1 1 1 2 2 2 0 HrpE/YscL/FliH and V-type ATPase subunit E 2Fe-2S_thioredx PF01257.19 EWM30264.1 - 1.1e-57 194.0 0.1 1.6e-57 193.4 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin PMI_typeI PF01238.21 EWM30265.1 - 1.7e-103 346.7 0.0 2.1e-103 346.4 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 EWM30265.1 - 0.00028 20.5 0.0 3.1 7.6 0.0 4.1 3 1 0 3 3 3 2 Cupin domain Cupin_1 PF00190.22 EWM30265.1 - 0.0071 16.0 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Cupin PTPlike_phytase PF14566.6 EWM30266.1 - 0.13 12.3 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate ELP6 PF09807.9 EWM30267.1 - 1.4e-16 60.7 0.1 1.2e-12 47.8 0.0 2.1 1 1 1 2 2 2 2 Elongation complex protein 6 TPT PF03151.16 EWM30268.1 - 3e-17 62.9 24.9 3.8e-17 62.6 24.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EWM30268.1 - 3.6e-08 33.7 33.1 1.2e-07 32.0 8.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family IBR PF01485.21 EWM30270.1 - 5.6e-08 32.9 9.7 5.6e-08 32.9 9.7 3.9 3 1 0 3 3 3 1 IBR domain, a half RING-finger domain Acetyltransf_1 PF00583.25 EWM30271.1 - 0.0063 16.7 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.6 EWM30271.1 - 0.026 15.2 0.0 0.07 13.8 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EWM30271.1 - 0.032 14.7 0.0 0.073 13.5 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PHF5 PF03660.14 EWM30271.1 - 0.1 12.8 0.1 0.15 12.3 0.1 1.2 1 0 0 1 1 1 0 PHF5-like protein OrfB_Zn_ribbon PF07282.11 EWM30271.1 - 0.48 10.4 2.5 0.96 9.4 2.5 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Methyltransf_5 PF01795.19 EWM30272.1 - 3.4e-78 263.3 0.0 5.3e-78 262.6 0.0 1.3 1 1 0 1 1 1 1 MraW methylase family Methyltransf_25 PF13649.6 EWM30272.1 - 0.012 16.3 0.1 0.036 14.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 EWM30272.1 - 0.016 14.5 0.0 0.18 11.1 0.0 2.0 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EWM30272.1 - 0.027 14.3 0.0 2.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 EWM30272.1 - 0.18 12.4 0.5 15 6.3 0.0 2.9 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_25 PF13649.6 EWM30273.1 - 4.8e-12 46.4 0.2 1.8e-09 38.2 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 EWM30273.1 - 2.5e-11 43.6 0.0 5.8e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM30273.1 - 4.2e-09 36.9 0.1 4.1e-08 33.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EWM30273.1 - 2.2e-08 34.7 0.0 7.3e-07 29.9 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Spermine_synth PF01564.17 EWM30273.1 - 0.012 15.0 0.0 0.035 13.5 0.0 1.7 1 0 0 1 1 1 0 Spermine/spermidine synthase domain MTS PF05175.14 EWM30273.1 - 0.03 13.9 0.0 1.2 8.7 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase small domain Complex1_LYR PF05347.15 EWM30274.1 - 1.9e-10 40.6 0.2 2.4e-10 40.3 0.2 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EWM30274.1 - 0.0033 18.1 0.5 0.0039 17.9 0.5 1.1 1 0 0 1 1 1 1 Complex1_LYR-like FANCI_S1-cap PF14674.6 EWM30274.1 - 0.057 13.5 0.0 0.082 13.0 0.0 1.3 1 0 0 1 1 1 0 FANCI solenoid 1 cap Beta-lactamase PF00144.24 EWM30274.1 - 0.14 11.4 0.1 0.14 11.3 0.1 1.2 1 0 0 1 1 1 0 Beta-lactamase ABC_membrane PF00664.23 EWM30275.1 - 8.5e-51 173.2 12.4 2.3e-29 102.9 1.7 2.4 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EWM30275.1 - 1.9e-42 145.1 0.0 1.3e-20 74.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 EWM30275.1 - 2.9e-10 40.2 0.1 0.0013 18.8 0.0 2.9 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_21 PF13304.6 EWM30275.1 - 6.9e-10 39.2 0.2 0.11 12.3 0.0 4.2 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EWM30275.1 - 1.5e-08 34.4 0.1 0.0023 17.4 0.0 4.1 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EWM30275.1 - 2e-06 27.4 0.5 0.045 13.5 0.0 3.1 3 0 0 3 3 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EWM30275.1 - 3.2e-06 27.1 0.1 0.0078 16.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 EWM30275.1 - 1.2e-05 25.5 2.4 0.014 15.5 0.1 2.4 2 0 0 2 2 2 2 Dynamin family AAA_22 PF13401.6 EWM30275.1 - 1.2e-05 25.6 0.1 0.3 11.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 EWM30275.1 - 8.3e-05 23.2 0.0 0.065 13.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EWM30275.1 - 9.4e-05 22.1 4.5 0.0011 18.5 0.2 2.7 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.6 EWM30275.1 - 0.00039 20.9 0.6 0.32 11.3 0.1 2.8 2 0 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 EWM30275.1 - 0.00046 20.4 0.1 0.86 9.8 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 EWM30275.1 - 0.00065 18.9 0.1 0.011 14.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 EWM30275.1 - 0.0052 16.3 0.2 1.8 8.0 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region FeoB_N PF02421.18 EWM30275.1 - 0.0053 16.3 0.2 3.9 7.0 0.1 2.8 3 0 0 3 3 2 1 Ferrous iron transport protein B cobW PF02492.19 EWM30275.1 - 0.0063 16.1 0.1 0.1 12.1 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 EWM30275.1 - 0.012 15.0 0.4 4.7 6.5 0.1 2.8 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_33 PF13671.6 EWM30275.1 - 0.014 15.6 0.3 1 9.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EWM30275.1 - 0.028 14.2 0.5 1.9 8.1 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 EWM30275.1 - 0.039 13.5 0.1 1.3 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EWM30275.1 - 0.04 13.9 0.1 4.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_15 PF13175.6 EWM30275.1 - 0.045 13.5 0.0 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.17 EWM30275.1 - 0.045 13.5 0.1 11 5.7 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein PduV-EutP PF10662.9 EWM30275.1 - 0.06 13.1 0.0 11 5.8 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.22 EWM30275.1 - 0.069 12.3 0.2 3 7.0 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.6 EWM30275.1 - 0.095 13.2 0.0 9.6 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EWM30275.1 - 0.11 12.5 0.1 1.8 8.4 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AIG1 PF04548.16 EWM30275.1 - 0.14 11.5 0.2 4.8 6.5 0.0 2.3 2 0 0 2 2 2 0 AIG1 family T2SSE PF00437.20 EWM30275.1 - 0.19 10.8 0.0 1.8 7.6 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein GTP_EFTU PF00009.27 EWM30275.1 - 0.21 11.1 0.0 2.1 7.9 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Septin PF00735.18 EWM30275.1 - 0.23 10.7 0.0 1.8 7.8 0.0 2.0 2 0 0 2 2 2 0 Septin DUF87 PF01935.17 EWM30275.1 - 0.37 10.8 6.2 1.8 8.6 0.2 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain MFS_1 PF07690.16 EWM30276.1 - 3.4e-35 121.6 26.8 3.4e-35 121.6 26.8 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EWM30276.1 - 4.8e-05 22.4 5.7 4.8e-05 22.4 5.7 3.1 1 1 2 3 3 3 2 MFS_1 like family MFS_3 PF05977.13 EWM30276.1 - 9.1e-05 21.0 15.9 0.00024 19.6 14.1 2.2 1 1 1 2 2 2 1 Transmembrane secretion effector Folate_carrier PF01770.18 EWM30276.1 - 0.014 14.2 3.5 0.034 12.9 3.5 1.6 1 0 0 1 1 1 0 Reduced folate carrier Sugar_tr PF00083.24 EWM30276.1 - 0.12 11.1 16.2 0.023 13.6 8.3 2.6 2 1 0 2 2 2 0 Sugar (and other) transporter OATP PF03137.20 EWM30276.1 - 0.4 8.9 8.1 0.046 12.0 1.2 2.7 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF4392 PF14336.6 EWM30277.1 - 5.6e-76 255.8 0.0 6.4e-76 255.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4392) Acyl_transf_3 PF01757.22 EWM30278.1 - 0.098 11.7 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Acyltransferase family ssDNA_TraI_N PF18272.1 EWM30278.1 - 0.1 12.7 1.3 0.14 12.2 0.2 1.8 2 0 0 2 2 2 0 single-stranded DNA binding TraI N-terminal subdomain Methyltransf_23 PF13489.6 EWM30279.1 - 8.5e-15 55.0 0.0 1.2e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM30279.1 - 4.4e-13 49.7 0.0 6.7e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EWM30279.1 - 7.6e-08 33.0 0.0 1.3e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EWM30279.1 - 6.3e-07 30.1 0.0 9.9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EWM30279.1 - 9.3e-05 21.9 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EWM30279.1 - 0.00054 19.8 0.0 0.00067 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EWM30279.1 - 0.014 15.0 0.0 0.025 14.2 0.0 1.5 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.15 EWM30279.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_29 PF03141.16 EWM30279.1 - 0.2 10.2 0.0 0.28 9.7 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase CS PF04969.16 EWM30280.1 - 8.5e-10 39.5 0.0 1.2e-09 39.0 0.0 1.3 1 0 0 1 1 1 1 CS domain DUF1522 PF07482.11 EWM30280.1 - 0.03 14.6 0.0 0.051 13.9 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1522) GTP_EFTU PF00009.27 EWM30281.1 - 5.4e-64 215.3 0.0 2.9e-63 212.9 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EWM30281.1 - 3.6e-30 104.2 0.1 1e-29 102.8 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 EWM30281.1 - 3.2e-20 71.9 0.0 1.5e-19 69.8 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.6 EWM30281.1 - 1.4e-14 53.9 0.0 3.5e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 EWM30281.1 - 3.9e-11 43.2 0.1 1.7e-10 41.1 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EWM30281.1 - 0.0012 18.9 0.2 0.0098 16.0 0.2 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EWM30281.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Dynamin family FAD_binding_4 PF01565.23 EWM30282.1 - 1.7e-07 31.0 0.0 2.6e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Reovirus_M2 PF05993.12 EWM30282.1 - 0.32 9.1 0.0 0.47 8.5 0.0 1.1 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) ArsA_ATPase PF02374.15 EWM30283.1 - 2.8e-130 433.9 0.0 7.7e-67 225.6 0.0 2.9 2 1 0 2 2 2 2 Anion-transporting ATPase CbiA PF01656.23 EWM30283.1 - 2.7e-20 72.7 0.0 4.1e-09 36.6 0.0 2.7 2 1 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EWM30283.1 - 1.5e-16 60.8 0.0 2.9e-07 30.6 0.1 3.9 4 0 0 4 4 4 2 AAA domain ParA PF10609.9 EWM30283.1 - 2.4e-13 50.1 10.8 0.00013 21.5 0.4 4.5 4 0 0 4 4 4 3 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 EWM30283.1 - 1.5e-07 31.1 1.0 0.0009 18.8 0.0 2.8 3 0 0 3 3 3 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 EWM30283.1 - 4e-07 29.9 1.9 0.033 13.8 0.2 3.1 3 0 0 3 3 3 2 SRP54-type protein, GTPase domain PhoH PF02562.16 EWM30283.1 - 2.4e-05 23.9 0.7 0.21 11.0 0.1 2.5 2 0 0 2 2 2 2 PhoH-like protein MeaB PF03308.16 EWM30283.1 - 0.00011 21.4 2.0 0.078 11.9 0.2 2.6 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB CBP_BcsQ PF06564.12 EWM30283.1 - 0.00025 20.6 1.2 0.43 10.0 0.1 2.3 2 0 0 2 2 2 2 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 EWM30283.1 - 0.0009 18.9 1.7 1.2 8.7 0.1 3.1 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EWM30283.1 - 0.00095 19.6 2.2 1.6 9.1 0.1 3.1 3 0 0 3 3 3 2 AAA ATPase domain IstB_IS21 PF01695.17 EWM30283.1 - 0.0014 18.4 0.3 1.4 8.6 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein MipZ PF09140.11 EWM30283.1 - 0.006 15.9 1.7 0.92 8.7 0.1 2.5 2 0 0 2 2 2 2 ATPase MipZ VirC1 PF07015.11 EWM30283.1 - 0.035 13.4 0.0 2.5 7.3 0.0 2.7 2 0 0 2 2 2 0 VirC1 protein DUF1611 PF07755.11 EWM30283.1 - 0.056 12.7 4.3 2.8 7.2 0.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1611_C) P-loop domain Zeta_toxin PF06414.12 EWM30283.1 - 0.056 12.7 1.2 1.4 8.2 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin LpxK PF02606.14 EWM30283.1 - 0.071 12.2 8.7 0.54 9.3 0.7 2.6 3 0 0 3 3 3 0 Tetraacyldisaccharide-1-P 4'-kinase DUF815 PF05673.13 EWM30283.1 - 0.091 11.9 0.0 1.7 7.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Kelch_3 PF13415.6 EWM30283.1 - 0.12 12.7 0.3 19 5.7 0.0 3.7 3 1 0 3 3 3 0 Galactose oxidase, central domain RsgA_GTPase PF03193.16 EWM30283.1 - 0.14 12.1 2.1 9 6.2 0.0 3.2 3 0 0 3 3 3 0 RsgA GTPase RNA_helicase PF00910.22 EWM30283.1 - 0.14 12.5 0.2 21 5.5 0.0 2.5 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.17 EWM30283.1 - 0.17 11.7 2.5 6.5 6.5 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein APS_kinase PF01583.20 EWM30283.1 - 0.19 11.6 2.4 9.1 6.1 0.1 2.8 3 0 0 3 3 3 0 Adenylylsulphate kinase AAA PF00004.29 EWM30283.1 - 0.32 11.4 2.2 27 5.2 0.1 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_26 PF13500.6 EWM30283.1 - 7.6 6.3 7.7 1.1e+02 2.5 0.1 4.0 4 0 0 4 4 4 0 AAA domain NACHT PF05729.12 EWM30283.1 - 9.6 6.1 7.5 48 3.8 0.2 3.3 3 0 0 3 3 3 0 NACHT domain HMG_box PF00505.19 EWM30285.1 - 4.5e-33 113.5 15.6 4.1e-16 59.2 4.7 2.9 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 EWM30285.1 - 3.4e-20 72.4 14.6 3.5e-13 49.9 1.9 3.1 3 0 0 3 3 3 2 HMG-box domain TRAP-gamma PF07074.12 EWM30285.1 - 0.4 10.2 0.9 0.79 9.3 0.0 1.8 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) YABBY PF04690.13 EWM30285.1 - 2.4 8.7 14.5 0.16 12.5 2.7 2.7 2 0 0 2 2 2 0 YABBY protein FYDLN_acid PF09538.10 EWM30285.1 - 6.1 7.6 7.2 0.69 10.6 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) HMG_box PF00505.19 EWM30286.1 - 4.5e-33 113.5 15.6 4.1e-16 59.2 4.7 2.9 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 EWM30286.1 - 3.4e-20 72.4 14.6 3.5e-13 49.9 1.9 3.1 3 0 0 3 3 3 2 HMG-box domain TRAP-gamma PF07074.12 EWM30286.1 - 0.4 10.2 0.9 0.79 9.3 0.0 1.8 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) YABBY PF04690.13 EWM30286.1 - 2.4 8.7 14.5 0.16 12.5 2.7 2.7 2 0 0 2 2 2 0 YABBY protein FYDLN_acid PF09538.10 EWM30286.1 - 6.1 7.6 7.2 0.69 10.6 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Tugs PF17840.1 EWM30288.1 - 0.017 15.3 0.0 0.028 14.6 0.0 1.3 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain ATG22 PF11700.8 EWM30288.1 - 0.025 13.2 0.0 0.05 12.2 0.0 1.4 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like RBM1CTR PF08081.11 EWM30288.1 - 0.23 11.5 3.0 0.43 10.7 3.0 1.3 1 0 0 1 1 1 0 RBM1CTR (NUC064) family p450 PF00067.22 EWM30289.1 - 2e-86 290.6 0.0 2.9e-86 290.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PNP_UDP_1 PF01048.20 EWM30290.1 - 1.5e-27 96.4 0.9 2.2e-27 95.8 0.9 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily Oxidored_q6 PF01058.22 EWM30291.1 - 2.2e-23 82.5 0.1 3.4e-23 81.9 0.1 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit PGI PF00342.19 EWM30292.1 - 6.7e-200 664.8 0.0 7.7e-200 664.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase FixQ PF05545.11 EWM30293.1 - 0.15 12.1 0.1 0.24 11.4 0.1 1.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Solute_trans_a PF03619.16 EWM30294.1 - 1e-21 77.7 6.7 1e-21 77.7 6.7 1.4 1 1 0 1 1 1 1 Organic solute transporter Ostalpha Phage_TTP_1 PF04630.12 EWM30296.1 - 0.23 10.8 0.0 0.31 10.3 0.0 1.1 1 0 0 1 1 1 0 Phage tail tube protein GST_N_3 PF13417.6 EWM30297.1 - 1e-16 61.1 0.0 2.2e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EWM30297.1 - 8.9e-16 58.0 0.0 2.1e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EWM30297.1 - 2.5e-07 30.6 0.0 7.8e-07 29.0 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EWM30297.1 - 0.00015 22.3 0.0 0.00028 21.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EWM30297.1 - 0.00049 20.3 0.0 0.0012 19.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EWM30297.1 - 0.0011 19.3 0.0 0.0026 18.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 EWM30297.1 - 0.0019 18.9 0.0 0.015 16.0 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain Glutaredoxin PF00462.24 EWM30297.1 - 0.005 17.0 0.0 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_C_3 PF14497.6 EWM30297.1 - 0.02 15.1 0.0 0.042 14.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Pkinase PF00069.25 EWM30299.1 - 4.9e-23 81.8 0.0 7.2e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM30299.1 - 1.3e-13 50.9 0.0 1.8e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EWM30299.1 - 2.1e-05 23.5 0.0 3.1e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EWM30299.1 - 0.057 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DNA_ligase_aden PF01653.18 EWM30300.1 - 6e-91 304.8 0.0 3.6e-69 233.3 0.0 3.1 2 1 0 2 2 2 2 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 EWM30300.1 - 1.9e-28 98.1 5.3 4.5e-28 97.0 5.3 1.6 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain HHH_2 PF12826.7 EWM30300.1 - 4.6e-09 36.2 0.0 5.9e-06 26.3 0.0 2.8 2 0 0 2 2 2 2 Helix-hairpin-helix motif DNA_ligase_ZBD PF03119.16 EWM30300.1 - 2.6e-06 27.3 6.4 6.6e-06 26.0 6.4 1.8 1 0 0 1 1 1 1 NAD-dependent DNA ligase C4 zinc finger domain BRCT PF00533.26 EWM30300.1 - 0.00029 21.1 0.0 0.0012 19.2 0.0 1.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EWM30300.1 - 0.0039 17.1 0.0 0.0081 16.1 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain zf-NADH-PPase PF09297.11 EWM30300.1 - 0.11 12.2 0.5 0.33 10.7 0.5 1.8 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain Sbt_1 PF05982.12 EWM30300.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Na+-dependent bicarbonate transporter superfamily Sas10 PF09368.10 EWM30301.1 - 6.9e-23 80.9 8.0 6.9e-23 80.9 8.0 2.8 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 EWM30301.1 - 8.1e-20 71.2 0.3 8.1e-20 71.2 0.3 3.5 3 1 1 4 4 4 1 Sas10/Utp3/C1D family YafQ_toxin PF15738.5 EWM30301.1 - 0.28 11.5 2.2 0.43 10.9 0.4 2.4 2 0 0 2 2 2 0 Bacterial toxin of type II toxin-antitoxin system, YafQ TLD PF07534.16 EWM30302.1 - 9.4e-24 84.2 0.0 2.1e-23 83.1 0.0 1.6 1 0 0 1 1 1 1 TLD RabGAP-TBC PF00566.18 EWM30302.1 - 2.3e-05 24.1 1.3 3.6e-05 23.5 1.3 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CD36 PF01130.21 EWM30303.1 - 5.2e-68 229.7 0.0 8.8e-67 225.6 0.0 2.4 2 1 0 2 2 2 1 CD36 family ATP1G1_PLM_MAT8 PF02038.16 EWM30303.1 - 0.0071 15.8 0.1 0.016 14.6 0.1 1.5 1 0 0 1 1 1 1 ATP1G1/PLM/MAT8 family UMP1 PF05348.11 EWM30303.1 - 0.061 13.5 0.0 0.21 11.8 0.0 1.8 2 0 0 2 2 2 0 Proteasome maturation factor UMP1 PRA-CH PF01502.18 EWM30304.1 - 4.5e-18 64.8 0.0 9.3e-18 63.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase DUF1751 PF08551.10 EWM30305.1 - 4.3e-06 27.2 5.1 4.3e-06 27.2 5.1 1.7 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Phosphatase PF15698.5 EWM30305.1 - 0.024 13.8 0.1 0.036 13.2 0.1 1.1 1 0 0 1 1 1 0 Phosphatase DUF1751 PF08551.10 EWM30306.1 - 1.4e-06 28.8 3.7 1.4e-06 28.8 3.7 1.6 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Phosphatase PF15698.5 EWM30306.1 - 0.02 14.1 0.1 0.029 13.5 0.1 1.1 1 0 0 1 1 1 0 Phosphatase Rhomboid PF01694.22 EWM30306.1 - 0.15 12.0 2.7 0.21 11.6 2.3 1.4 1 1 0 1 1 1 0 Rhomboid family TK PF00265.18 EWM30306.1 - 0.59 10.0 1.9 2 8.2 0.6 2.0 1 1 1 2 2 2 0 Thymidine kinase HSP70 PF00012.20 EWM30307.1 - 1.1e-125 420.1 11.2 8e-119 397.5 0.3 2.9 2 1 1 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 EWM30307.1 - 1.2e-06 27.6 0.5 1.9e-05 23.6 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein Apolipoprotein PF01442.18 EWM30307.1 - 1.7 8.5 9.3 1.1 9.1 1.1 2.9 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain adh_short PF00106.25 EWM30308.1 - 1e-24 87.1 0.0 1.2e-23 83.6 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EWM30308.1 - 2.3e-12 47.0 0.0 1.1e-11 44.8 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM30308.1 - 3.7e-07 30.2 0.0 5.7e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 KR domain RAP PF08373.10 EWM30309.1 - 1.1e-08 35.1 0.0 1.9e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 RAP domain Es2 PF09751.9 EWM30311.1 - 1.7e-50 173.1 0.0 1.3e-48 166.9 0.0 2.7 2 1 0 2 2 2 1 Nuclear protein Es2 CobN-Mg_chel PF02514.16 EWM30311.1 - 0.13 10.0 0.1 0.17 9.6 0.1 1.1 1 0 0 1 1 1 0 CobN/Magnesium Chelatase zf-C3HC4_3 PF13920.6 EWM30312.1 - 0.0082 16.0 13.2 0.017 15.0 13.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) GCV_T_C PF08669.11 EWM30312.1 - 0.031 14.2 0.6 4 7.4 0.1 2.4 1 1 1 2 2 2 0 Glycine cleavage T-protein C-terminal barrel domain zf-C3HC4 PF00097.25 EWM30312.1 - 0.16 11.8 16.0 0.34 10.8 16.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EWM30312.1 - 0.91 9.4 15.7 2.2 8.2 15.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EWM30312.1 - 2 8.5 15.2 4.2 7.4 15.2 1.6 1 0 0 1 1 1 0 zinc-RING finger domain IMS PF00817.20 EWM30313.1 - 0.0011 18.9 0.0 0.0047 16.9 0.0 2.0 1 1 0 1 1 1 1 impB/mucB/samB family Complex1_LYR PF05347.15 EWM30314.1 - 2.2e-15 56.4 0.2 3.1e-15 56.0 0.2 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EWM30314.1 - 0.00017 22.3 0.1 0.0002 22.0 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 EWM30314.1 - 0.00037 21.0 0.4 0.00045 20.8 0.4 1.3 1 1 0 1 1 1 1 Complex1_LYR-like GDE_N_bis PF14742.6 EWM30314.1 - 0.024 14.2 0.0 0.026 14.1 0.0 1.1 1 0 0 1 1 1 0 N-terminal domain of (some) glycogen debranching enzymes HSBP1 PF06825.12 EWM30316.1 - 1.3e-17 63.4 0.3 1.9e-17 62.8 0.3 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 HMMR_C PF15908.5 EWM30316.1 - 0.0026 18.1 0.0 0.0034 17.7 0.0 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor C-terminal RNA_pol_Rpb4 PF03874.16 EWM30317.1 - 2.5e-08 34.3 0.0 5.8e-08 33.1 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb4 Abhydrolase_1 PF00561.20 EWM30318.1 - 1.9e-13 50.6 0.1 6.8e-13 48.9 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EWM30318.1 - 7.9e-11 41.7 0.0 2.1e-10 40.3 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EWM30318.1 - 9.3e-10 39.5 0.1 3.4e-09 37.6 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF726 PF05277.12 EWM30318.1 - 0.0069 15.4 0.0 0.01 14.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Lipase_3 PF01764.25 EWM30318.1 - 0.055 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF900 PF05990.12 EWM30318.1 - 0.055 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF717 PF05338.12 EWM30319.1 - 0.1 12.7 0.1 0.44 10.7 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF717) PTPRCAP PF15713.5 EWM30319.1 - 0.55 10.5 4.9 1.2 9.4 4.9 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Methyltransf_15 PF09445.10 EWM30320.1 - 5.4e-37 126.9 0.0 1.2e-36 125.8 0.0 1.6 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 EWM30320.1 - 2.1e-06 27.6 0.0 4.7e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 EWM30320.1 - 2.2e-05 25.0 0.0 4.9e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EWM30320.1 - 7.1e-05 22.5 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 EWM30320.1 - 0.00025 20.8 0.0 0.00045 20.0 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 EWM30320.1 - 0.00044 20.1 0.0 0.00076 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EWM30320.1 - 0.0018 18.9 0.0 0.004 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 EWM30320.1 - 0.0045 16.2 0.0 0.0081 15.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.7 EWM30320.1 - 0.0046 16.9 0.0 0.0074 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EWM30320.1 - 0.015 14.7 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF3606 PF12244.8 EWM30320.1 - 1.7 8.7 5.2 29 4.7 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3606) Porphobil_deam PF01379.20 EWM30321.1 - 2.2e-75 252.6 0.0 2.9e-75 252.3 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 EWM30321.1 - 1.8e-17 63.4 0.3 3.2e-17 62.7 0.3 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain NAPRTase_N PF17767.1 EWM30323.1 - 4.6e-38 130.4 0.1 1e-37 129.3 0.1 1.6 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase_C PF17956.1 EWM30323.1 - 1.9e-30 105.5 0.0 3.1e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase PF04095.16 EWM30323.1 - 8.2e-10 38.7 0.0 1.4e-08 34.6 0.0 2.1 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family QRPTase_N PF02749.16 EWM30323.1 - 0.01 15.9 0.0 0.044 13.8 0.0 2.1 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, N-terminal domain Ribophorin_II PF05817.14 EWM30325.1 - 3.8e-64 217.4 0.0 4.6e-64 217.1 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Invasin_D3 PF09134.10 EWM30325.1 - 0.099 13.0 0.5 0.35 11.2 0.0 2.1 3 0 0 3 3 3 0 Invasin, domain 3 UQ_con PF00179.26 EWM30326.1 - 1.7e-34 118.4 0.0 2.6e-34 117.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EWM30326.1 - 0.011 16.1 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 0 RWD domain Toprim_2 PF13155.6 EWM30326.1 - 0.14 12.6 0.0 0.4 11.1 0.0 1.7 1 0 0 1 1 1 0 Toprim-like DUF4187 PF13821.6 EWM30327.1 - 7.4e-18 64.1 3.6 1.5e-17 63.1 3.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 EWM30327.1 - 1.9e-11 43.7 1.6 1.9e-11 43.7 1.6 1.8 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 EWM30327.1 - 7.5e-05 22.7 1.4 0.00017 21.6 1.4 1.6 1 0 0 1 1 1 1 G-patch domain ATP-synt_ab PF00006.25 EWM30329.1 - 1.3e-104 348.4 0.0 2.1e-104 347.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 EWM30329.1 - 3.4e-37 127.0 0.0 6.2e-37 126.1 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 EWM30329.1 - 2.7e-14 53.4 0.2 8.2e-14 51.9 0.2 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain EFP_N PF08207.12 EWM30330.1 - 1.4e-26 92.2 0.1 4.8e-26 90.6 0.1 2.0 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Elong-fact-P_C PF09285.11 EWM30330.1 - 1.9e-22 78.7 0.9 4.4e-22 77.6 0.6 1.8 2 0 0 2 2 2 1 Elongation factor P, C-terminal EFP PF01132.20 EWM30330.1 - 1.2e-15 57.3 1.4 2.1e-15 56.5 1.4 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain GATase_5 PF13507.6 EWM30331.1 - 4.9e-104 347.0 0.0 8.1e-104 346.3 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 EWM30331.1 - 6.3e-41 140.1 4.5 3.5e-23 82.5 0.3 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 EWM30331.1 - 8.6e-17 61.2 0.0 1.5e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 EWM30331.1 - 4e-10 40.1 0.0 9.5e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 EWM30331.1 - 0.02 15.6 0.1 0.34 11.6 0.0 2.9 2 1 1 3 3 3 0 AIR synthase related protein, N-terminal domain AAA_34 PF13872.6 EWM30332.1 - 6.4e-96 320.8 0.0 9.2e-96 320.3 0.0 1.2 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.6 EWM30332.1 - 1.1e-62 212.1 3.9 8.7e-62 209.2 3.9 2.1 1 1 0 1 1 1 1 C-terminal domain on Strawberry notch homologue ResIII PF04851.15 EWM30332.1 - 0.058 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit WD40 PF00400.32 EWM30333.1 - 2.9e-34 116.5 12.1 2.1e-07 31.5 1.3 8.6 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM30333.1 - 1.4e-17 63.7 0.0 0.00024 21.3 0.1 5.8 3 3 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EWM30333.1 - 1.6e-05 24.1 0.3 1 8.2 0.0 3.9 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EWM30333.1 - 0.022 14.7 0.1 2.8 8.0 0.0 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat IKI3 PF04762.12 EWM30333.1 - 0.092 10.7 0.0 3.6 5.4 0.0 2.1 2 0 0 2 2 2 0 IKI3 family PQQ_3 PF13570.6 EWM30333.1 - 0.88 10.1 9.5 1.2 9.7 0.2 4.3 4 0 0 4 4 4 0 PQQ-like domain ThiF PF00899.21 EWM30334.1 - 3.8e-96 321.1 0.0 3.1e-69 233.0 0.0 2.3 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EWM30334.1 - 5.3e-61 206.7 0.0 9e-61 206.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 EWM30334.1 - 1.1e-16 61.3 0.0 2.5e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 EWM30334.1 - 2.9e-07 30.6 0.0 6.8e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Shikimate_DH PF01488.20 EWM30334.1 - 3.9e-06 27.0 0.0 0.037 14.1 0.0 2.6 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EWM30334.1 - 0.00013 22.4 0.3 0.018 15.5 0.0 2.9 3 0 0 3 3 3 1 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 EWM30334.1 - 0.0032 16.7 0.0 0.47 9.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase E1_FCCH PF16190.5 EWM30334.1 - 0.0036 17.5 0.0 0.0091 16.2 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain Toprim_3 PF13362.6 EWM30334.1 - 0.0083 16.5 0.4 0.1 13.0 0.1 2.6 2 0 0 2 2 2 1 Toprim domain Pyr_redox PF00070.27 EWM30334.1 - 0.01 16.4 0.2 0.67 10.6 0.0 2.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EWM30334.1 - 0.032 14.5 2.8 1.7 8.9 0.0 3.5 4 0 0 4 4 4 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 EWM30334.1 - 0.052 12.9 0.0 6.5 6.1 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EWM30334.1 - 0.11 12.7 1.0 25 5.1 0.0 3.8 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Cupin_3 PF05899.12 EWM30334.1 - 0.12 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_2 PF07883.11 EWM30334.1 - 0.18 11.5 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 Cupin domain Aconitase PF00330.20 EWM30335.1 - 9e-148 493.1 0.0 1.1e-147 492.8 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EWM30335.1 - 5.6e-46 156.1 0.0 1.3e-45 154.9 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain Myb_Cef PF11831.8 EWM30335.1 - 0.16 11.6 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 pre-mRNA splicing factor component CTP_transf_1 PF01148.20 EWM30338.1 - 6e-56 190.1 15.8 7.8e-56 189.8 15.8 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Ndc1_Nup PF09531.10 EWM30338.1 - 4.7 5.8 6.9 6.3 5.4 6.0 1.7 1 1 1 2 2 2 0 Nucleoporin protein Ndc1-Nup Ribosomal_L37ae PF01780.19 EWM30340.1 - 4.8e-40 135.5 8.1 5.5e-40 135.3 8.1 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 EWM30340.1 - 0.0011 19.0 0.9 0.0018 18.4 0.9 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Elf1 PF05129.13 EWM30340.1 - 0.021 14.9 1.3 0.035 14.1 1.3 1.6 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like DUF2175 PF09943.9 EWM30340.1 - 0.024 14.9 0.4 2.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Zn_Tnp_IS1595 PF12760.7 EWM30340.1 - 0.16 12.0 2.1 0.38 10.8 2.2 1.6 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-Sec23_Sec24 PF04810.15 EWM30340.1 - 0.99 9.5 4.0 1.9 8.6 0.2 2.2 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger Malate_synthase PF01274.22 EWM30341.1 - 8.5e-114 380.7 0.0 1.1e-113 380.4 0.0 1.0 1 0 0 1 1 1 1 Malate synthase TRAM_LAG1_CLN8 PF03798.16 EWM30342.1 - 3.5e-27 95.4 13.5 3.9e-27 95.3 12.3 1.6 2 0 0 2 2 2 1 TLC domain SOG2 PF10428.9 EWM30343.1 - 0.0038 16.5 1.5 0.0049 16.1 1.5 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein Spectrin PF00435.21 EWM30343.1 - 0.008 16.6 2.0 0.042 14.4 2.0 1.9 1 1 0 1 1 1 1 Spectrin repeat API5 PF05918.11 EWM30343.1 - 1.9 7.2 12.5 6.2 5.5 7.9 2.0 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) Ndc1_Nup PF09531.10 EWM30343.1 - 6.7 5.3 5.3 7 5.2 5.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Filamin PF00630.19 EWM30344.1 - 9.3e-10 39.3 0.0 2.7e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 Filamin/ABP280 repeat zf-RING_UBOX PF13445.6 EWM30344.1 - 1.9e-09 37.4 4.0 6.3e-09 35.7 4.0 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EWM30344.1 - 7.2e-09 35.5 2.1 7.2e-09 35.5 2.1 2.9 3 1 1 4 4 3 1 zinc-RING finger domain zf-B_box PF00643.24 EWM30344.1 - 3.2e-06 27.2 26.6 3.7e-05 23.8 7.1 3.6 3 0 0 3 3 3 2 B-box zinc finger zf-C3HC4 PF00097.25 EWM30344.1 - 6.7e-06 25.9 2.5 6.7e-06 25.9 2.5 2.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EWM30344.1 - 6.9e-06 26.3 2.4 6.9e-06 26.3 2.4 3.4 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EWM30344.1 - 0.00037 20.3 2.3 0.00037 20.3 2.3 2.7 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EWM30344.1 - 0.00088 19.4 4.4 0.00088 19.4 4.4 3.4 4 0 0 4 4 3 1 zinc finger of C3HC4-type, RING NHL PF01436.21 EWM30344.1 - 0.039 14.0 2.7 26 5.1 0.0 3.9 4 0 0 4 4 4 0 NHL repeat Phasin PF05597.11 EWM30344.1 - 0.12 12.4 2.1 0.24 11.4 2.1 1.4 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) RasGAP_C PF03836.15 EWM30344.1 - 0.14 12.3 0.3 0.23 11.6 0.3 1.3 1 0 0 1 1 1 0 RasGAP C-terminus Prefoldin_2 PF01920.20 EWM30345.1 - 6.6e-20 71.0 1.4 7e-20 71.0 0.8 1.3 1 1 0 1 1 1 1 Prefoldin subunit PspA_IM30 PF04012.12 EWM30345.1 - 0.004 16.8 2.3 0.033 13.8 0.2 2.0 2 0 0 2 2 2 1 PspA/IM30 family MAD PF05557.13 EWM30345.1 - 0.032 12.6 2.4 0.94 7.8 0.2 2.0 2 0 0 2 2 2 0 Mitotic checkpoint protein SKA1 PF07160.12 EWM30345.1 - 0.055 13.3 3.2 0.061 13.2 0.6 1.8 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 FliJ PF02050.16 EWM30345.1 - 0.064 13.5 11.7 0.29 11.4 4.0 2.1 1 1 1 2 2 2 0 Flagellar FliJ protein GAT PF03127.14 EWM30345.1 - 0.066 13.5 1.5 0.17 12.2 0.9 1.8 2 0 0 2 2 2 0 GAT domain CLZ PF16526.5 EWM30345.1 - 0.11 12.9 2.6 0.16 12.4 0.1 2.1 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Spc24 PF08286.11 EWM30345.1 - 0.69 10.2 4.7 0.53 10.5 0.9 2.1 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 SlyX PF04102.12 EWM30345.1 - 2.7 8.7 7.5 12 6.6 1.7 2.5 2 1 0 2 2 2 0 SlyX DENN PF02141.21 EWM30346.1 - 2e-42 145.3 5.8 3.3e-42 144.5 5.8 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 EWM30346.1 - 2.9e-08 33.5 0.4 7e-08 32.3 0.4 1.7 1 0 0 1 1 1 1 dDENN domain PPR_2 PF13041.6 EWM30346.1 - 0.0012 19.0 0.0 0.0084 16.3 0.0 2.3 1 1 1 2 2 2 1 PPR repeat family PPR PF01535.20 EWM30346.1 - 0.015 15.5 0.0 0.27 11.6 0.0 2.6 2 0 0 2 2 2 0 PPR repeat DZR PF12773.7 EWM30346.1 - 0.053 13.5 0.5 0.13 12.4 0.5 1.5 1 0 0 1 1 1 0 Double zinc ribbon TF_Zn_Ribbon PF08271.12 EWM30346.1 - 0.14 11.7 0.3 0.3 10.6 0.3 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding DUF4989 PF16379.5 EWM30346.1 - 0.2 10.9 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4989) DENN PF02141.21 EWM30347.1 - 2e-42 145.3 5.8 3.3e-42 144.5 5.8 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 EWM30347.1 - 2.9e-08 33.5 0.4 7e-08 32.3 0.4 1.7 1 0 0 1 1 1 1 dDENN domain PPR_2 PF13041.6 EWM30347.1 - 0.0012 19.0 0.0 0.0084 16.3 0.0 2.3 1 1 1 2 2 2 1 PPR repeat family PPR PF01535.20 EWM30347.1 - 0.015 15.5 0.0 0.27 11.6 0.0 2.6 2 0 0 2 2 2 0 PPR repeat DZR PF12773.7 EWM30347.1 - 0.053 13.5 0.5 0.13 12.4 0.5 1.5 1 0 0 1 1 1 0 Double zinc ribbon TF_Zn_Ribbon PF08271.12 EWM30347.1 - 0.14 11.7 0.3 0.3 10.6 0.3 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding DUF4989 PF16379.5 EWM30347.1 - 0.2 10.9 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4989) Melibiase PF02065.18 EWM30348.1 - 1.4e-16 60.4 0.1 2.3e-16 59.7 0.1 1.2 1 0 0 1 1 1 1 Melibiase GHL6 PF14871.6 EWM30348.1 - 0.047 13.8 0.0 0.095 12.8 0.0 1.4 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 Raffinose_syn PF05691.12 EWM30348.1 - 0.22 9.3 0.0 0.4 8.4 0.0 1.3 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 MS_channel PF00924.18 EWM30349.1 - 1.6e-34 119.2 0.0 2.3e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel ExoD PF06055.12 EWM30349.1 - 0.04 13.3 0.2 0.088 12.2 0.2 1.5 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD CAP_N PF01213.19 EWM30349.1 - 3 7.3 5.2 5.1 6.5 5.2 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DEAD PF00270.29 EWM30350.1 - 5.2e-39 133.8 0.0 8.4e-39 133.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EWM30350.1 - 7.7e-22 77.7 0.0 4.7e-21 75.2 0.0 2.3 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EWM30350.1 - 3.8e-14 52.7 2.2 4.8e-14 52.3 0.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EWM30350.1 - 4.1e-06 26.9 0.0 9.4e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EWM30350.1 - 0.0082 16.4 0.1 0.058 13.7 0.1 2.3 1 1 0 1 1 1 1 AAA domain SNF2_N PF00176.23 EWM30350.1 - 0.011 14.5 0.0 0.025 13.3 0.0 1.5 2 0 0 2 2 2 0 SNF2 family N-terminal domain Cyclin_N PF00134.23 EWM30351.1 - 3.3e-07 30.1 0.0 5.4e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 EWM30351.1 - 1.5e-06 28.5 0.0 0.0001 22.6 0.0 2.4 2 0 0 2 2 2 1 Cyclin C-terminal domain Rad60-SLD_2 PF13881.6 EWM30352.1 - 1.9e-08 34.4 0.0 0.00019 21.5 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EWM30352.1 - 0.021 15.4 0.0 3 8.5 0.0 2.3 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain zf-A20 PF01754.16 EWM30353.1 - 2.8e-09 36.7 8.1 6.2e-09 35.6 8.1 1.6 1 0 0 1 1 1 1 A20-like zinc finger zf-AN1 PF01428.16 EWM30353.1 - 4e-09 36.5 7.7 4e-09 36.5 7.7 1.9 2 0 0 2 2 2 1 AN1-like Zinc finger DUF4428 PF14471.6 EWM30353.1 - 0.0088 15.9 4.9 0.3 11.0 0.3 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4428) Dscam_C PF12355.8 EWM30353.1 - 0.021 15.8 0.5 0.041 14.9 0.2 1.6 1 1 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal FYVE_2 PF02318.16 EWM30353.1 - 5.2 7.3 7.7 0.93 9.7 0.7 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger zf-A20 PF01754.16 EWM30354.1 - 2.8e-09 36.7 8.1 6.2e-09 35.6 8.1 1.6 1 0 0 1 1 1 1 A20-like zinc finger zf-AN1 PF01428.16 EWM30354.1 - 4e-09 36.5 7.7 4e-09 36.5 7.7 1.9 2 0 0 2 2 2 1 AN1-like Zinc finger DUF4428 PF14471.6 EWM30354.1 - 0.0088 15.9 4.9 0.3 11.0 0.3 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4428) Dscam_C PF12355.8 EWM30354.1 - 0.021 15.8 0.5 0.041 14.9 0.2 1.6 1 1 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal FYVE_2 PF02318.16 EWM30354.1 - 5.2 7.3 7.7 0.93 9.7 0.7 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger PA28_beta PF02252.18 EWM30356.1 - 1.5e-40 138.2 0.0 2.2e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 EWM30356.1 - 0.00055 19.9 1.2 0.0014 18.6 0.5 2.0 2 0 0 2 2 2 1 Proteasome activator pa28 alpha subunit DUF276 PF03434.13 EWM30356.1 - 0.04 13.1 0.1 0.059 12.5 0.1 1.2 1 0 0 1 1 1 0 DUF276 PikAIV_N PF18605.1 EWM30356.1 - 1.3 8.6 8.8 0.59 9.8 1.1 3.1 3 0 0 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Sec20 PF03908.13 EWM30357.1 - 2.2e-06 27.5 0.1 6.7e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 Sec20 V-SNARE PF05008.15 EWM30357.1 - 0.00024 21.4 1.9 0.00024 21.4 1.9 2.3 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 EWM30357.1 - 0.004 17.4 0.4 0.012 15.9 0.4 1.8 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus NPV_P10 PF05531.12 EWM30357.1 - 0.0072 16.8 0.7 1.8 9.1 0.5 3.1 3 0 0 3 3 3 1 Nucleopolyhedrovirus P10 protein MtrB PF05440.12 EWM30357.1 - 0.012 16.1 0.0 0.028 14.8 0.0 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B MerR-DNA-bind PF09278.11 EWM30357.1 - 0.028 14.9 0.2 33 5.1 0.1 3.2 3 0 0 3 3 3 0 MerR, DNA binding Sugarporin_N PF11471.8 EWM30357.1 - 0.041 13.8 2.4 0.05 13.6 0.7 2.1 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension DUF4407 PF14362.6 EWM30357.1 - 0.082 12.2 8.1 0.15 11.4 8.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Snapin_Pallidin PF14712.6 EWM30357.1 - 0.19 12.2 3.2 6.4 7.3 0.2 3.0 2 1 1 3 3 3 0 Snapin/Pallidin HemX PF04375.14 EWM30357.1 - 0.27 10.5 6.1 0.25 10.6 3.8 1.9 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4094 PF13334.6 EWM30357.1 - 0.31 11.5 4.5 0.82 10.1 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) ERM PF00769.19 EWM30357.1 - 0.35 10.6 10.2 0.047 13.5 2.4 2.3 2 1 0 2 2 2 0 Ezrin/radixin/moesin family Syntaxin-6_N PF09177.11 EWM30357.1 - 0.51 10.9 6.6 35 5.0 6.6 2.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Spc7 PF08317.11 EWM30357.1 - 0.84 8.4 8.6 2.1 7.1 1.4 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein XhlA PF10779.9 EWM30357.1 - 1 9.6 10.9 0.67 10.2 0.4 3.5 3 1 2 5 5 4 0 Haemolysin XhlA DUF4140 PF13600.6 EWM30357.1 - 1.1 9.7 8.3 3.2 8.2 0.5 2.9 3 2 0 3 3 2 0 N-terminal domain of unknown function (DUF4140) TMF_DNA_bd PF12329.8 EWM30357.1 - 1.3 9.1 12.2 4.1 7.5 0.8 3.6 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF16 PF01519.16 EWM30357.1 - 1.6 9.2 6.1 1.3 9.5 1.9 2.2 1 1 0 2 2 2 0 Protein of unknown function DUF16 Caskin-tail PF16632.5 EWM30357.1 - 2.2 8.8 5.5 1.8 9.0 1.2 2.5 2 0 0 2 2 2 0 C-terminal region of Caskin FlaC_arch PF05377.11 EWM30357.1 - 3.9 8.0 6.4 16 6.0 0.6 3.4 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) CCDC-167 PF15188.6 EWM30357.1 - 5.5 7.4 7.1 5.3 7.5 0.8 2.6 3 0 0 3 3 2 0 Coiled-coil domain-containing protein 167 Glycos_transf_2 PF00535.26 EWM30358.1 - 7.6e-31 107.2 0.0 9.4e-31 106.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EWM30358.1 - 1.7e-12 47.7 0.0 2.2e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EWM30358.1 - 6e-07 29.1 0.0 1.3e-06 28.0 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 EWM30358.1 - 0.04 13.4 0.0 0.052 13.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Syja_N PF02383.18 EWM30359.1 - 1.5e-81 274.2 0.0 2.5e-81 273.5 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain Virulence_fact PF13769.6 EWM30359.1 - 0.022 15.0 0.4 0.091 13.0 0.1 2.1 2 0 0 2 2 2 0 Virulence factor SPT16 PF08644.11 EWM30360.1 - 1.4e-51 174.6 0.2 3.6e-51 173.3 0.2 1.8 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 EWM30360.1 - 6.7e-27 94.5 0.0 1.2e-26 93.7 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 FACT-Spt16_Nlob PF14826.6 EWM30360.1 - 4.6e-25 88.3 0.0 1.2e-24 87.0 0.0 1.7 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Rtt106 PF08512.12 EWM30360.1 - 4.7e-12 46.2 0.3 1.1e-11 45.0 0.3 1.5 1 0 0 1 1 1 1 Histone chaperone Rttp106-like CK_II_beta PF01214.18 EWM30361.1 - 4e-67 225.6 2.1 5.4e-57 192.5 0.9 2.1 1 1 0 2 2 2 2 Casein kinase II regulatory subunit Herpes_capsid PF06112.11 EWM30361.1 - 0.7 9.9 9.2 5.4 7.0 1.7 2.3 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein VPS13_C PF16909.5 EWM30363.1 - 1.4e-20 73.8 2.6 1.3e-17 64.1 0.1 2.3 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 EWM30363.1 - 2.4e-14 53.4 0.0 8.8e-07 28.6 0.0 3.9 4 0 0 4 4 4 3 SHR-binding domain of vacuolar-sorting associated protein 13 EF-hand_7 PF13499.6 EWM30363.1 - 2.7e-06 27.7 0.1 6.4e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EWM30363.1 - 0.00015 21.1 0.1 0.00046 19.5 0.0 1.9 2 0 0 2 2 2 1 EF hand ATG_C PF09333.11 EWM30363.1 - 0.00018 21.8 0.0 0.00058 20.2 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain EF-hand_5 PF13202.6 EWM30363.1 - 0.00073 18.9 0.3 0.011 15.3 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EWM30363.1 - 0.0013 18.5 0.0 0.0046 16.8 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 EWM30363.1 - 0.15 11.9 0.1 0.55 10.1 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair Nup96 PF12110.8 EWM30364.1 - 4.2e-47 160.7 0.0 7.8e-47 159.8 0.0 1.5 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 EWM30364.1 - 1e-29 103.6 0.0 1.5e-29 103.0 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase WD40 PF00400.32 EWM30365.1 - 1.8e-42 142.5 16.8 4.4e-08 33.7 0.6 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.8 EWM30365.1 - 0.00032 19.5 4.6 0.43 9.1 0.0 4.4 1 1 3 5 5 5 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EWM30365.1 - 0.0014 18.9 2.4 16 5.9 0.1 4.6 1 1 5 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EWM30365.1 - 0.017 13.9 0.0 5.2 5.7 0.0 3.2 1 1 2 3 3 3 0 Nup133 N terminal like mRNA_cap_enzyme PF01331.19 EWM30366.1 - 0.19 11.5 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 mRNA capping enzyme, catalytic domain Snurportin1 PF11538.8 EWM30366.1 - 4 7.7 7.3 0.5 10.6 2.7 1.9 2 0 0 2 2 2 0 Snurportin1 RabGAP-TBC PF00566.18 EWM30367.1 - 3.1e-11 43.3 0.0 4.5e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Sensor PF13796.6 EWM30367.1 - 4.3 7.4 8.8 1.3 9.1 0.1 2.9 2 1 0 2 2 2 0 Putative sensor eIF3_subunit PF08597.10 EWM30368.1 - 5.8e-15 55.9 9.8 7.5e-15 55.5 9.8 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Nop14 PF04147.12 EWM30368.1 - 0.043 12.1 11.0 0.058 11.6 11.0 1.1 1 0 0 1 1 1 0 Nop14-like family Rrn6 PF10214.9 EWM30368.1 - 0.084 11.4 5.3 0.12 10.9 5.3 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor CDC45 PF02724.14 EWM30368.1 - 0.34 9.1 4.2 0.39 8.9 4.2 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4592 PF15262.6 EWM30368.1 - 1.4 9.6 5.4 1.9 9.2 3.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4592) FmiP_Thoc5 PF09766.9 EWM30369.1 - 5.8e-30 104.8 0.0 2.5e-26 92.8 0.0 2.1 2 0 0 2 2 2 2 Fms-interacting protein/Thoc5 RWD PF05773.22 EWM30369.1 - 0.16 12.3 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 RWD domain DivIC PF04977.15 EWM30369.1 - 0.39 10.5 2.1 13 5.7 0.1 2.7 2 0 0 2 2 2 0 Septum formation initiator Peptidase_M16_C PF05193.21 EWM30370.1 - 5.9e-35 120.9 0.0 1.2e-34 120.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EWM30370.1 - 2e-32 112.2 0.1 4.3e-32 111.2 0.0 1.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DUF1104 PF06518.11 EWM30370.1 - 0.13 12.6 0.5 0.37 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) RCC1 PF00415.18 EWM30371.1 - 3.9e-74 245.1 24.3 1.7e-15 57.4 0.0 8.3 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EWM30371.1 - 5e-42 140.9 31.7 5.3e-09 35.7 0.9 8.4 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat Uricase PF01014.18 EWM30372.1 - 4.3e-51 172.6 0.0 3.7e-29 101.6 0.4 2.1 2 0 0 2 2 2 2 Uricase FolB PF02152.18 EWM30372.1 - 0.052 14.1 0.2 0.13 12.8 0.1 1.7 2 0 0 2 2 2 0 Dihydroneopterin aldolase Proteasome PF00227.26 EWM30373.1 - 4.1e-17 62.3 0.0 8.4e-17 61.3 0.0 1.5 1 1 0 1 1 1 1 Proteasome subunit ACOX PF01756.19 EWM30374.1 - 2e-38 131.8 0.0 4.9e-31 107.7 0.0 2.2 2 0 0 2 2 2 2 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 EWM30374.1 - 1.1e-27 97.0 0.0 1.9e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 EWM30374.1 - 3.7e-12 46.3 0.0 9.4e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EWM30374.1 - 6.1e-05 23.3 0.1 0.004 17.4 0.0 2.9 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EWM30374.1 - 0.067 13.9 0.1 0.54 10.9 0.0 2.3 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain DnaJ PF00226.31 EWM30375.1 - 2e-25 88.7 3.6 3.7e-25 87.8 3.6 1.5 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.20 EWM30375.1 - 5.5e-18 64.9 0.0 9.1e-14 51.3 0.1 2.5 2 0 0 2 2 2 2 Thioredoxin Armet PF10208.9 EWM30375.1 - 2.5e-08 34.0 0.1 5.5e-08 32.9 0.1 1.6 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding Thioredoxin_3 PF13192.6 EWM30375.1 - 0.016 15.3 0.1 0.037 14.1 0.1 1.6 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_4 PF13462.6 EWM30375.1 - 0.041 14.0 0.7 0.29 11.3 0.2 2.5 2 1 1 3 3 3 0 Thioredoxin AhpC-TSA PF00578.21 EWM30375.1 - 0.056 13.4 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 AhpC/TSA family HyaE PF07449.11 EWM30375.1 - 0.19 11.7 0.0 0.73 9.8 0.0 2.0 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Nfu_N PF08712.11 EWM30376.1 - 3.6e-26 91.0 0.0 8.1e-26 89.9 0.0 1.6 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 EWM30376.1 - 1.3e-24 86.1 0.0 2.3e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain Pkinase PF00069.25 EWM30377.1 - 3e-62 210.4 0.0 6.9e-62 209.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM30377.1 - 7.9e-33 113.8 0.0 3.7e-27 95.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EWM30377.1 - 0.072 13.0 0.3 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family eIF-6 PF01912.18 EWM30379.1 - 1.4e-80 269.4 0.3 2.3e-80 268.7 0.3 1.3 1 0 0 1 1 1 1 eIF-6 family Peptidase_C48 PF02902.19 EWM30380.1 - 1.2e-11 44.8 0.0 3.4e-11 43.4 0.0 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Pkinase PF00069.25 EWM30382.1 - 7.9e-62 209.0 0.0 9.4e-62 208.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM30382.1 - 6.1e-32 110.9 0.0 8.3e-32 110.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EWM30382.1 - 1.2e-07 31.0 0.0 1.7e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EWM30382.1 - 1.3e-05 25.2 0.3 0.002 18.1 0.0 2.6 3 0 0 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 EWM30382.1 - 0.0029 17.0 0.3 0.0029 17.0 0.3 1.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EWM30382.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Aldo_ket_red PF00248.21 EWM30383.1 - 2.6e-71 240.2 0.0 3.3e-71 239.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF4336 PF14234.6 EWM30385.1 - 6.7e-76 255.5 4.8 4.6e-56 190.3 0.5 2.6 1 1 2 3 3 3 3 Domain of unknown function (DUF4336) Glucosamine_iso PF01182.20 EWM30386.1 - 1.7e-08 34.6 0.0 9.3e-07 28.9 0.0 2.5 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase PIG-L PF02585.17 EWM30386.1 - 2.8e-05 24.8 0.0 0.00075 20.1 0.0 3.0 2 1 0 2 2 2 1 GlcNAc-PI de-N-acetylase Ribosomal_L24e PF01246.20 EWM30387.1 - 2.2e-23 82.2 0.5 2.2e-23 82.2 0.5 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e MRP-L27 PF09809.9 EWM30388.1 - 1.7e-13 50.4 0.3 2.2e-13 50.0 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Ras PF00071.22 EWM30389.1 - 5.3e-58 195.2 0.1 7e-58 194.8 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EWM30389.1 - 1.8e-35 121.8 0.2 2.8e-35 121.2 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EWM30389.1 - 6.6e-16 58.3 0.1 1e-15 57.7 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EWM30389.1 - 1.2e-06 28.0 0.0 1.7e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EWM30389.1 - 2e-05 24.7 0.0 3.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EWM30389.1 - 0.001 18.7 0.1 0.0022 17.6 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EWM30389.1 - 0.001 18.5 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EWM30389.1 - 0.0064 16.9 0.0 0.016 15.6 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 EWM30389.1 - 0.038 13.4 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein DUF815 PF05673.13 EWM30389.1 - 0.047 12.8 0.0 0.16 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Septin PF00735.18 EWM30389.1 - 0.077 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Septin RsgA_GTPase PF03193.16 EWM30389.1 - 0.087 12.7 0.1 1.4 8.8 0.0 2.5 1 1 2 3 3 3 0 RsgA GTPase AAA_22 PF13401.6 EWM30389.1 - 0.14 12.4 0.0 0.52 10.6 0.0 2.0 2 1 0 2 2 2 0 AAA domain ABC2_membrane PF01061.24 EWM30390.1 - 6.1e-42 143.4 12.1 6.1e-42 143.4 12.1 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 EWM30390.1 - 3.8e-24 85.8 0.0 3.4e-23 82.7 0.0 2.1 2 0 0 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.7 EWM30390.1 - 1.8e-06 27.3 14.6 4.8e-06 25.9 14.4 1.8 1 1 1 2 2 2 1 ABC-2 family transporter protein SMC_N PF02463.19 EWM30390.1 - 3.6e-05 23.3 0.1 0.00035 20.1 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EWM30390.1 - 6.5e-05 23.4 0.1 0.00013 22.4 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EWM30390.1 - 0.00016 21.6 0.4 0.14 11.9 0.1 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EWM30390.1 - 0.0012 18.8 0.1 0.0023 17.8 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EWM30390.1 - 0.003 17.3 0.1 0.0081 15.9 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EWM30390.1 - 0.005 17.4 0.0 0.013 16.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EWM30390.1 - 0.0063 16.9 0.0 0.088 13.2 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EWM30390.1 - 0.0088 16.3 0.0 0.024 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 EWM30390.1 - 0.015 14.9 0.1 0.033 13.8 0.0 1.6 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 EWM30390.1 - 0.032 13.8 0.3 0.39 10.3 0.3 2.2 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EWM30390.1 - 0.034 14.2 0.1 0.081 13.0 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 EWM30390.1 - 0.074 12.4 0.0 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_24 PF13479.6 EWM30390.1 - 0.075 12.7 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EWM30390.1 - 0.076 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_28 PF13521.6 EWM30390.1 - 0.1 12.9 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 EWM30390.1 - 0.15 12.1 0.1 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 Dynamin family AAA_18 PF13238.6 EWM30390.1 - 0.16 12.6 0.0 0.3 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EWM30390.1 - 0.16 11.0 0.0 0.47 9.5 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein PduV-EutP PF10662.9 EWM30390.1 - 0.21 11.3 0.3 0.54 10.0 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Fe-S_biosyn PF01521.20 EWM30391.1 - 4.3e-13 49.4 0.0 6.1e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis tRNA-synt_2 PF00152.20 EWM30392.1 - 1e-83 281.1 0.1 1.4e-83 280.6 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EWM30392.1 - 2.2e-12 46.8 0.6 7.8e-12 45.0 0.5 2.0 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EWM30392.1 - 0.055 12.9 0.4 2.9 7.3 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) RMI1_N PF08585.12 EWM30393.1 - 1.7e-21 77.0 0.7 4.5e-15 56.0 0.1 2.1 1 1 1 2 2 2 2 RecQ mediated genome instability protein MMS1_N PF10433.9 EWM30394.1 - 1.5e-141 472.4 0.0 2.1e-141 471.9 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EWM30394.1 - 1.2e-83 281.1 0.0 1.6e-81 274.1 0.0 2.5 2 0 0 2 2 2 2 CPSF A subunit region SelK_SelG PF10961.8 EWM30395.1 - 0.0014 19.2 2.1 0.0021 18.6 1.7 1.5 1 1 0 1 1 1 1 Selenoprotein SelK_SelG PIP5K PF01504.18 EWM30396.1 - 1.4e-54 185.2 0.0 2.4e-53 181.1 0.0 2.1 1 1 1 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase TFIIA PF03153.13 EWM30396.1 - 0.11 12.4 8.2 0.15 12.0 8.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 EWM30396.1 - 1.4 9.5 9.4 28 5.4 10.4 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region F-box-like PF12937.7 EWM30397.1 - 3.1e-05 23.8 0.5 6e-05 22.9 0.5 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EWM30397.1 - 0.016 15.1 0.1 0.039 13.8 0.1 1.6 1 0 0 1 1 1 0 F-box domain TFIIA PF03153.13 EWM30397.1 - 0.041 13.9 3.4 0.054 13.5 3.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med3 PF11593.8 EWM30397.1 - 3.3 6.8 9.5 4.8 6.3 9.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal AIM24 PF01987.17 EWM30398.1 - 1e-17 64.6 0.1 1.3e-17 64.2 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 SMI1_KNR4 PF09346.10 EWM30398.1 - 0.059 13.8 0.0 0.096 13.1 0.0 1.2 1 0 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) DUF1445 PF07286.12 EWM30399.1 - 4e-64 214.9 0.0 5.2e-64 214.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) DBR1 PF05011.13 EWM30400.1 - 2.6e-27 96.0 0.0 3.9e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 EWM30400.1 - 1.1e-09 39.1 0.1 2.2e-09 38.1 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EWM30400.1 - 0.028 14.6 0.0 0.091 13.0 0.0 2.0 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain PIG-U PF06728.13 EWM30401.1 - 8.2e-30 104.1 20.5 1.1e-29 103.6 20.5 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U 8TM_micro PF17028.5 EWM30401.1 - 0.84 9.3 4.8 0.87 9.2 0.5 2.2 2 0 0 2 2 2 0 8TM Microsporidial transmembrane domain TFIIA PF03153.13 EWM30402.1 - 0.14 12.1 7.5 0.16 11.9 7.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2046 PF09755.9 EWM30403.1 - 1.5e-26 93.4 45.2 3.9e-19 69.0 21.6 2.2 1 1 1 2 2 2 2 Uncharacterized conserved protein H4 (DUF2046) Prominin PF05478.11 EWM30403.1 - 0.52 8.2 9.7 0.7 7.8 9.7 1.1 1 0 0 1 1 1 0 Prominin Herpes_UL6 PF01763.16 EWM30403.1 - 1.2 7.6 18.2 0.23 9.9 6.3 2.1 1 1 1 2 2 2 0 Herpesvirus UL6 like Baculo_PEP_C PF04513.12 EWM30403.1 - 1.6 8.7 11.8 8.1 6.5 8.9 2.7 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pap_E4 PF02711.14 EWM30405.1 - 0.29 12.1 5.0 0.48 11.4 5.0 1.4 1 0 0 1 1 1 0 E4 protein UAA PF08449.11 EWM30406.1 - 1.4e-61 208.3 18.5 1.9e-61 207.9 18.5 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EWM30406.1 - 0.00034 20.8 9.5 0.00034 20.8 9.5 3.0 2 1 0 3 3 3 2 EamA-like transporter family HIG_1_N PF04588.13 EWM30408.1 - 1.2e-17 63.8 1.7 7.9e-09 35.6 1.4 2.2 2 0 0 2 2 2 2 Hypoxia induced protein conserved region P5CR_dimer PF14748.6 EWM30409.1 - 2.2e-31 108.1 0.1 3.8e-31 107.4 0.1 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EWM30409.1 - 2e-15 57.1 0.0 3.9e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EWM30409.1 - 5e-06 26.8 0.0 8.9e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 EWM30409.1 - 0.00064 19.7 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 EWM30409.1 - 0.00076 19.4 0.3 0.011 15.6 0.1 2.1 1 1 1 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EWM30409.1 - 0.0009 19.3 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.22 EWM30409.1 - 0.0013 19.5 0.0 0.0026 18.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ApbA PF02558.16 EWM30409.1 - 0.003 17.2 0.0 0.0053 16.4 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_C PF03720.15 EWM30409.1 - 0.009 16.4 0.0 0.023 15.1 0.0 1.6 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 2-Hacid_dh_C PF02826.19 EWM30409.1 - 0.03 13.7 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Arabino_trans_N PF17689.1 EWM30409.1 - 0.053 13.7 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 Arabinosyltransferase concanavalin like domain NAD_binding_7 PF13241.6 EWM30409.1 - 0.13 12.7 0.0 0.66 10.4 0.0 2.1 1 1 1 2 2 2 0 Putative NAD(P)-binding Sulfotransfer_1 PF00685.27 EWM30410.1 - 2.4e-28 99.4 0.0 3.6e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EWM30410.1 - 6.6e-07 29.9 0.7 0.013 15.9 0.0 2.9 2 1 1 3 3 3 2 Sulfotransferase family DnaJ PF00226.31 EWM30411.1 - 4e-21 74.9 0.0 7.2e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain TMEM144 PF07857.12 EWM30412.1 - 8.3e-26 90.7 4.5 5.6e-23 81.4 1.0 2.0 2 0 0 2 2 2 2 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 EWM30412.1 - 1.5e-06 27.7 0.8 2.5e-06 27.0 0.8 1.3 1 0 0 1 1 1 1 Sugar transport protein Ureide_permease PF07168.11 EWM30412.1 - 0.87 8.3 4.8 0.93 8.2 4.8 1.3 1 1 0 1 1 1 0 Ureide permease TPR_2 PF07719.17 EWM30413.1 - 1.2e-07 31.3 3.7 0.0075 16.3 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EWM30413.1 - 0.04 13.7 0.4 12 5.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EWM30413.1 - 0.043 14.5 7.5 1.9 9.2 0.3 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EWM30413.1 - 0.09 13.6 6.0 19 6.4 0.8 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat HemY_N PF07219.13 EWM30413.1 - 0.14 12.4 0.4 2.2 8.5 0.0 2.6 3 0 0 3 3 3 0 HemY protein N-terminus Pkinase PF00069.25 EWM30414.1 - 1.4e-35 123.0 0.0 5.4e-20 71.9 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EWM30414.1 - 2.2e-12 46.8 0.2 4.8e-07 29.3 0.1 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase COPI_assoc PF08507.10 EWM30415.1 - 2.2e-09 37.5 4.9 3e-09 37.0 4.9 1.1 1 0 0 1 1 1 1 COPI associated protein Pex14_N PF04695.13 EWM30415.1 - 5.1 7.7 8.8 0.49 11.0 3.9 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Syntaxin-6_N PF09177.11 EWM30416.1 - 2e-05 25.1 4.2 2e-05 25.1 4.2 3.1 3 1 0 3 3 3 1 Syntaxin 6, N-terminal SNARE PF05739.19 EWM30416.1 - 0.0035 17.3 2.8 0.0035 17.3 2.8 2.4 2 0 0 2 2 2 1 SNARE domain DegS PF05384.11 EWM30416.1 - 0.011 15.2 4.7 0.011 15.2 4.7 2.4 2 0 0 2 2 2 0 Sensor protein DegS betaPIX_CC PF16523.5 EWM30416.1 - 0.25 11.2 7.9 0.36 10.7 4.3 2.7 2 1 0 2 2 2 0 betaPIX coiled coil DASH_Duo1 PF08651.10 EWM30416.1 - 0.32 10.8 4.5 0.6 9.9 0.4 2.9 3 0 0 3 3 3 0 DASH complex subunit Duo1 Lipoprotein_6 PF01441.19 EWM30416.1 - 0.67 9.9 8.3 0.59 10.1 1.7 2.6 2 1 1 3 3 3 0 Lipoprotein PhaP_Bmeg PF09602.10 EWM30416.1 - 3.4 7.6 14.5 0.89 9.5 4.4 3.1 2 2 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) CCDC-167 PF15188.6 EWM30416.1 - 4 7.8 7.3 3.1 8.2 0.1 3.0 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 AAA_13 PF13166.6 EWM30416.1 - 6 5.4 11.4 6.4 5.3 2.7 2.1 2 0 0 2 2 2 0 AAA domain COG5 PF10392.9 EWM30416.1 - 9.5 6.4 8.8 3.1 8.0 1.8 2.7 3 0 0 3 3 3 0 Golgi transport complex subunit 5 14-3-3 PF00244.20 EWM30417.1 - 9.8e-103 342.4 0.7 1.1e-102 342.2 0.7 1.0 1 0 0 1 1 1 1 14-3-3 protein Rhomboid PF01694.22 EWM30418.1 - 5.9e-10 39.3 7.5 5.9e-10 39.3 7.5 2.4 2 1 0 2 2 2 1 Rhomboid family PX PF00787.24 EWM30419.1 - 2.5e-16 59.6 0.0 5.6e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 PX domain RPAP1_N PF08621.10 EWM30419.1 - 0.11 12.3 1.1 0.29 10.9 1.1 1.7 1 0 0 1 1 1 0 RPAP1-like, N-terminal Tim17 PF02466.19 EWM30420.1 - 1.1e-12 48.3 7.1 1.6e-12 47.8 7.1 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Romo1 PF10247.9 EWM30420.1 - 0.0053 17.1 1.0 0.0053 17.1 1.0 2.0 2 0 0 2 2 2 1 Reactive mitochondrial oxygen species modulator 1 TIM21 PF08294.11 EWM30421.1 - 4.2e-15 55.9 0.0 6.7e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 TIM21 DUF5344 PF17279.2 EWM30422.1 - 0.13 12.9 0.0 0.2 12.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5344) Antimicrobial_8 PF08103.11 EWM30422.1 - 6.4 7.1 5.7 1.3 9.3 1.9 2.0 2 0 0 2 2 2 0 Uperin family ALG11_N PF15924.5 EWM30423.1 - 1.9e-81 273.1 0.0 3.1e-81 272.4 0.0 1.3 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 EWM30423.1 - 8.3e-27 93.8 0.0 1.4e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EWM30423.1 - 3.5e-14 53.4 0.0 1.2e-13 51.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Fer2_4 PF13510.6 EWM30424.1 - 7.5e-16 58.0 0.1 1.4e-15 57.1 0.1 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 EWM30424.1 - 3.7e-15 55.2 0.4 3.7e-15 55.2 0.4 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 EWM30424.1 - 5.1e-09 36.0 0.9 1.6e-08 34.3 0.1 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 EWM30424.1 - 0.025 14.4 1.4 1.7 8.6 0.4 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_19 PF06902.11 EWM30424.1 - 0.25 11.4 1.9 4.3 7.5 1.9 2.6 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster 4PPT_N PF17837.1 EWM30425.1 - 0.018 15.2 0.0 5.6 7.2 0.0 2.2 2 0 0 2 2 2 0 4'-phosphopantetheinyl transferase N-terminal domain Ten1_2 PF15490.6 EWM30426.1 - 1.1e-26 92.9 0.6 1.3e-26 92.7 0.6 1.0 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit Rep_fac-A_3 PF08661.11 EWM30426.1 - 2.2e-06 28.0 0.0 3.8e-06 27.2 0.0 1.4 1 1 0 1 1 1 1 Replication factor A protein 3 Actin PF00022.19 EWM30427.1 - 2.2e-86 290.0 0.0 1.4e-85 287.4 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EWM30427.1 - 0.18 10.6 0.0 0.31 9.8 0.0 1.4 1 0 0 1 1 1 0 MreB/Mbl protein 2OG-FeII_Oxy_2 PF13532.6 EWM30428.1 - 1.6e-08 35.0 0.0 2.6e-08 34.3 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_hydro_18 PF00704.28 EWM30429.1 - 1.4e-07 31.6 0.0 1.8e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Arm PF00514.23 EWM30430.1 - 6.1e-51 169.0 27.7 8.4e-10 38.4 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EWM30430.1 - 2e-19 69.7 14.1 1.4e-07 31.9 0.4 6.4 5 1 1 6 6 6 5 HEAT-like repeat IBB PF01749.20 EWM30430.1 - 8e-15 55.1 0.3 1.7e-14 54.0 0.3 1.6 1 0 0 1 1 1 1 Importin beta binding domain HEAT_2 PF13646.6 EWM30430.1 - 9e-12 45.2 9.6 0.0003 21.1 0.2 5.4 2 1 4 6 6 6 5 HEAT repeats HEAT PF02985.22 EWM30430.1 - 9.7e-12 44.1 12.4 0.0013 18.8 0.1 7.9 8 0 0 8 8 8 3 HEAT repeat Arm_3 PF16186.5 EWM30430.1 - 1.2e-11 44.0 3.9 1.7e-11 43.5 2.7 1.8 2 0 0 2 2 2 1 Atypical Arm repeat Cnd1 PF12717.7 EWM30430.1 - 2.4e-07 31.0 0.0 0.023 14.7 0.1 3.2 1 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 EWM30430.1 - 0.0046 17.5 6.8 12 6.9 0.0 6.2 6 1 0 6 6 6 1 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.9 EWM30430.1 - 0.0052 16.8 0.1 0.25 11.4 0.0 2.8 2 1 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain NopRA1 PF16201.5 EWM30430.1 - 0.072 12.7 0.1 75 2.8 0.0 3.8 2 2 2 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 WD40 PF00400.32 EWM30431.1 - 3.4e-10 40.3 7.1 1.8e-07 31.7 0.4 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM30431.1 - 6e-10 39.3 0.7 0.00099 19.4 0.2 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain DPPIV_N PF00930.21 EWM30431.1 - 0.028 13.2 0.5 0.13 11.0 0.1 2.0 1 1 1 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Abhydrolase_1 PF00561.20 EWM30432.1 - 5.8e-17 62.2 0.0 3.7e-12 46.4 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EWM30432.1 - 8.1e-15 54.7 0.1 1.2e-11 44.4 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EWM30432.1 - 9.1e-08 33.0 0.1 9.1e-08 33.0 0.1 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family AXE1 PF05448.12 EWM30432.1 - 4.2e-07 29.0 0.3 0.02 13.6 0.0 2.9 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 EWM30432.1 - 3e-06 26.9 0.0 0.023 14.2 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EWM30432.1 - 2.3e-05 24.3 0.3 4.9e-05 23.3 0.3 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EWM30432.1 - 2.6e-05 24.0 0.0 6.6e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.18 EWM30432.1 - 8.4e-05 22.3 0.0 0.0017 18.0 0.0 2.6 3 0 0 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) DUF818 PF05677.12 EWM30432.1 - 0.00029 19.9 0.0 0.0004 19.4 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) DLH PF01738.18 EWM30432.1 - 0.0007 19.2 0.0 0.014 15.0 0.0 2.3 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 EWM30432.1 - 0.0012 18.8 0.0 0.0081 16.1 0.0 2.0 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 EWM30432.1 - 0.022 14.6 0.0 0.45 10.3 0.0 2.4 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Beach PF02138.18 EWM30433.1 - 2.8e-35 122.1 0.0 4.2e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 EWM30433.1 - 9.6e-06 26.3 5.4 4.5 8.3 0.0 6.0 5 0 0 5 5 5 1 WD domain, G-beta repeat Pkinase PF00069.25 EWM30433.1 - 0.0016 17.8 0.0 0.0028 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain ANAPC4_WD40 PF12894.7 EWM30433.1 - 0.0027 18.0 0.1 4 7.8 0.0 3.5 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 EWM30433.1 - 0.045 13.7 0.1 1.2 9.2 0.0 3.0 3 0 0 3 3 3 0 PQQ enzyme repeat Nup160 PF11715.8 EWM30433.1 - 0.071 11.7 0.0 7.9 5.0 0.0 3.1 3 0 0 3 3 3 0 Nucleoporin Nup120/160 CENP-B_dimeris PF09026.10 EWM30433.1 - 6 7.3 5.3 27 5.2 3.6 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain HAD_2 PF13419.6 EWM30434.1 - 2.7e-16 60.2 0.0 1.4e-15 57.8 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EWM30434.1 - 2.5e-11 44.3 0.1 1.2e-10 42.0 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EWM30434.1 - 2.6e-06 27.4 0.0 4.7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EWM30434.1 - 0.04 14.3 0.1 0.099 13.0 0.1 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase IMS PF00817.20 EWM30435.1 - 2.6e-40 137.9 0.0 4.3e-40 137.1 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EWM30435.1 - 1.5e-15 58.0 0.1 3.3e-15 56.8 0.1 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain RNF220 PF15926.5 EWM30435.1 - 0.00033 20.4 0.2 0.00066 19.4 0.2 1.4 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase RNF220 Peptidase_C78 PF07910.13 EWM30439.1 - 1.7e-38 132.2 0.0 2.4e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.19 EWM30439.1 - 0.18 11.2 0.0 0.5 9.7 0.0 1.7 2 0 0 2 2 2 0 Peptidase family C54 Peptidase_C78 PF07910.13 EWM30440.1 - 1.3e-38 132.6 0.0 1.9e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.19 EWM30440.1 - 0.15 11.5 0.0 0.38 10.1 0.0 1.7 2 0 0 2 2 2 0 Peptidase family C54 Aldo_ket_red PF00248.21 EWM30441.1 - 2.5e-37 128.7 0.0 6.5e-37 127.3 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family TPR_8 PF13181.6 EWM30442.1 - 0.0015 18.6 6.5 0.79 10.1 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat Clathrin PF00637.20 EWM30442.1 - 0.0018 18.2 0.8 1.7 8.5 0.0 3.7 3 1 1 4 4 4 2 Region in Clathrin and VPS TPR_7 PF13176.6 EWM30442.1 - 0.0055 16.6 14.2 2.7 8.2 0.5 6.1 7 1 0 7 7 7 3 Tetratricopeptide repeat Nic96 PF04097.14 EWM30442.1 - 0.056 11.9 3.5 0.68 8.3 0.0 3.6 4 0 0 4 4 4 0 Nup93/Nic96 SNAP PF14938.6 EWM30442.1 - 0.093 12.1 0.1 0.093 12.1 0.1 3.3 3 1 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 EWM30442.1 - 0.63 10.3 22.9 1.1 9.5 0.2 7.2 8 1 0 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.28 EWM30442.1 - 0.73 9.8 8.5 5.4 7.0 0.2 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 EWM30442.1 - 0.81 9.4 4.7 1.1 9.0 0.4 3.1 3 0 0 3 3 3 0 TPR repeat TPR_10 PF13374.6 EWM30442.1 - 2.4 8.2 5.8 3.6 7.6 0.3 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EWM30442.1 - 6.9 7.0 21.5 1.3 9.4 1.3 6.4 6 2 0 7 7 7 0 Tetratricopeptide repeat O-FucT PF10250.9 EWM30443.1 - 2.2e-53 182.2 0.0 2.8e-53 181.8 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Form_Nir_trans PF01226.17 EWM30444.1 - 9.7e-60 201.8 25.7 1.3e-59 201.5 25.7 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter Mito_carr PF00153.27 EWM30445.1 - 2.3e-38 130.0 9.0 4.2e-15 55.4 0.0 4.7 5 0 0 5 5 5 4 Mitochondrial carrier protein EF-hand_1 PF00036.32 EWM30445.1 - 0.0092 15.5 0.3 0.02 14.4 0.3 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EWM30445.1 - 0.041 13.8 4.9 0.044 13.7 0.5 2.5 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 EWM30445.1 - 0.12 12.8 0.1 0.32 11.5 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair EamA PF00892.20 EWM30446.1 - 1.1e-08 35.3 31.5 1.4e-08 35.0 10.9 2.3 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 EWM30446.1 - 1.2e-07 31.4 17.3 1.5e-07 31.1 17.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family PCI PF01399.27 EWM30447.1 - 8.8e-06 26.2 0.1 3.2e-05 24.4 0.0 2.0 2 1 0 2 2 2 1 PCI domain CK2S PF15011.6 EWM30447.1 - 0.013 15.4 0.1 0.022 14.7 0.1 1.3 1 0 0 1 1 1 0 Casein Kinase 2 substrate Hrs_helical PF12210.8 EWM30447.1 - 0.06 13.9 2.2 0.11 13.0 2.2 1.5 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate CSN7a_helixI PF18392.1 EWM30447.1 - 0.065 13.1 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain PI3K_P85_iSH2 PF16454.5 EWM30447.1 - 0.073 12.7 2.2 0.12 11.9 2.2 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain MIP-T3_C PF17749.1 EWM30447.1 - 0.96 9.4 4.3 2.4 8.1 4.3 1.6 1 1 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region MIF4G_like PF09088.11 EWM30449.1 - 1.2e-12 48.0 0.1 2e-12 47.3 0.1 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 EWM30449.1 - 2.4e-10 40.3 0.0 3.9e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.19 EWM30449.1 - 4e-05 23.3 0.0 0.00011 21.9 0.0 1.6 1 1 0 1 1 1 1 MIF4G domain Pyr_redox_2 PF07992.14 EWM30450.1 - 1.9e-46 158.7 1.2 2.7e-46 158.2 1.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EWM30450.1 - 7.4e-29 100.2 2.8 4.9e-28 97.6 0.4 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EWM30450.1 - 1.5e-14 54.3 5.4 1.1e-12 48.3 0.2 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EWM30450.1 - 1.1e-08 34.9 0.5 1.9e-08 34.1 0.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EWM30450.1 - 5.2e-07 28.7 4.2 0.0016 17.2 0.3 3.1 2 1 1 3 3 3 2 HI0933-like protein NAD_binding_8 PF13450.6 EWM30450.1 - 1.7e-06 28.1 0.6 0.00096 19.3 0.1 3.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EWM30450.1 - 0.00016 20.9 3.7 0.00039 19.6 0.6 2.8 3 0 0 3 3 3 1 FAD binding domain 3HCDH_N PF02737.18 EWM30450.1 - 0.00048 20.1 0.4 0.0047 16.8 0.1 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EWM30450.1 - 0.0012 18.2 0.1 0.058 12.7 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 EWM30450.1 - 0.0087 15.3 0.3 1.9 7.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EWM30450.1 - 0.017 14.3 0.2 1.6 7.9 0.0 2.3 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.12 EWM30450.1 - 0.033 13.2 0.6 5.1 6.0 0.2 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein XdhC_C PF13478.6 EWM30450.1 - 0.052 14.1 0.1 2.7 8.5 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain TrkA_N PF02254.18 EWM30450.1 - 0.084 13.1 0.1 1 9.6 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain GIDA PF01134.22 EWM30450.1 - 0.14 11.2 2.2 0.5 9.4 0.1 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A DAO PF01266.24 EWM30450.1 - 5.4 6.5 10.8 19 4.7 0.0 3.7 2 2 1 4 4 4 0 FAD dependent oxidoreductase TPT PF03151.16 EWM30451.1 - 2.7e-103 345.3 14.9 3.2e-103 345.1 14.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EWM30451.1 - 2.4e-13 50.4 25.7 3.5e-08 33.7 5.2 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EWM30451.1 - 3.4e-05 23.2 8.9 3.7e-05 23.1 7.8 1.6 1 1 1 2 2 2 1 UAA transporter family DUF2070 PF09843.9 EWM30451.1 - 7.1 4.8 16.2 2.5 6.3 2.6 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Myb_DNA-binding PF00249.31 EWM30452.1 - 2e-12 47.1 0.3 3.7e-12 46.2 0.3 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EWM30452.1 - 0.00079 19.6 0.1 0.0014 18.8 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EWM30452.1 - 0.0023 17.8 0.2 0.0045 16.8 0.2 1.4 1 0 0 1 1 1 1 Myb DNA-binding like Ras PF00071.22 EWM30455.1 - 1.1e-48 164.9 0.0 1.4e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EWM30455.1 - 1.2e-30 106.2 0.0 2.4e-30 105.2 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EWM30455.1 - 2.2e-09 37.0 0.0 2.9e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EWM30455.1 - 3.6e-05 23.8 0.0 6.6e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 EWM30455.1 - 0.00016 22.0 0.0 0.00057 20.2 0.0 1.8 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.12 EWM30455.1 - 0.0011 18.4 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EWM30455.1 - 0.034 13.6 0.0 0.061 12.7 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.18 EWM30455.1 - 0.044 13.1 0.0 0.097 11.9 0.0 1.5 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 EWM30455.1 - 0.058 13.8 0.0 0.083 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 EWM30455.1 - 0.069 13.1 0.0 1.4 8.8 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 EWM30455.1 - 0.073 12.8 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain ArgoMid PF16487.5 EWM30455.1 - 0.089 13.1 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Mid domain of argonaute AAA_33 PF13671.6 EWM30455.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EWM30455.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE G-alpha PF00503.20 EWM30455.1 - 0.27 10.3 2.2 4.5 6.3 0.1 2.8 2 1 1 3 3 3 0 G-protein alpha subunit zf-CCCH PF00642.24 EWM30456.1 - 3.5e-33 112.9 35.9 7.4e-10 38.5 5.2 4.4 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EWM30456.1 - 6.2e-19 67.4 52.0 1.6e-05 24.8 5.2 4.5 5 0 0 5 5 5 4 Zinc finger domain zf-CCCH_4 PF18044.1 EWM30456.1 - 2.8e-11 43.0 38.3 0.00021 21.0 6.0 4.5 4 0 0 4 4 4 4 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EWM30456.1 - 4e-09 36.6 37.1 0.025 15.0 2.2 4.7 4 0 0 4 4 4 4 RNA-binding, Nab2-type zinc finger Torus PF16131.5 EWM30456.1 - 0.015 16.0 24.4 0.14 12.9 0.2 4.1 2 1 2 4 4 4 0 Torus domain zf-CCCH PF00642.24 EWM30457.1 - 1.4e-19 69.5 20.3 5.1e-10 39.0 5.2 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EWM30457.1 - 4.3e-09 36.1 29.8 1.1e-05 25.3 5.2 3.5 4 0 0 4 4 4 2 Zinc finger domain zf-CCCH_4 PF18044.1 EWM30457.1 - 2.5e-08 33.5 21.0 0.00014 21.5 6.0 3.4 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EWM30457.1 - 1.1e-05 25.7 21.5 0.017 15.5 2.2 3.7 3 0 0 3 3 3 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 EWM30457.1 - 0.00021 22.0 1.9 0.091 13.5 0.2 2.2 2 0 0 2 2 2 2 Torus domain O-FucT PF10250.9 EWM30459.1 - 8.3e-35 121.1 0.0 1.1e-34 120.6 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF1279 PF06916.13 EWM30460.1 - 1.2e-22 80.3 0.3 3.2e-22 78.9 0.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Proteasome PF00227.26 EWM30461.1 - 2.6e-26 92.3 0.4 6e-26 91.1 0.4 1.5 1 1 0 1 1 1 1 Proteasome subunit PP2C_2 PF13672.6 EWM30461.1 - 0.081 12.5 0.3 0.62 9.7 0.1 1.9 1 1 1 2 2 2 0 Protein phosphatase 2C Hep_59 PF07052.11 EWM30462.1 - 6.2e-09 36.6 0.0 6.2e-09 36.6 0.0 2.8 1 1 1 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 DUF1336 PF07059.12 EWM30463.1 - 1.1e-48 166.3 0.0 6.1e-48 163.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1336) PX PF00787.24 EWM30463.1 - 4e-15 55.8 0.0 8.2e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 PX domain Glyco_transf_64 PF09258.10 EWM30464.1 - 1.5e-54 184.9 0.0 4.5e-26 91.6 0.0 2.0 2 0 0 2 2 2 2 Glycosyl transferase family 64 domain BTK PF00779.19 EWM30465.1 - 3.2e-05 23.6 1.1 3.2e-05 23.6 1.1 3.1 3 0 0 3 3 3 1 BTK motif CHORD PF04968.12 EWM30465.1 - 4.6 8.0 14.3 1.7e+02 3.0 14.3 2.6 1 1 0 1 1 1 0 CHORD mRNA_decap_C PF16741.5 EWM30466.1 - 2.6e-05 23.4 0.1 4e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 mRNA-decapping enzyme C-terminus DCP1 PF06058.13 EWM30466.1 - 0.023 14.6 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 Dcp1-like decapping family Abhydrolase_6 PF12697.7 EWM30467.1 - 3.6e-18 67.0 0.9 5.2e-18 66.5 0.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EWM30467.1 - 4.3e-13 49.5 0.0 5.5e-12 45.9 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EWM30467.1 - 1.4e-10 40.9 0.0 4.8e-10 39.1 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 EWM30467.1 - 0.2 11.2 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 EWM30468.1 - 3.4e-17 63.8 0.3 4.6e-17 63.4 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EWM30468.1 - 4.3e-11 42.9 0.0 6.6e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EWM30468.1 - 2e-09 37.1 0.0 2.7e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 EWM30468.1 - 0.18 11.4 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Glyco_transf_15 PF01793.16 EWM30469.1 - 1.5e-42 146.0 0.0 7.4e-40 137.2 0.0 3.3 3 1 0 3 3 3 1 Glycolipid 2-alpha-mannosyltransferase Methyltransf_22 PF13383.6 EWM30469.1 - 1.9e-24 86.6 0.0 4e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 EWM30469.1 - 0.022 14.8 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase FkbM domain DUF3527 PF12043.8 EWM30469.1 - 0.2 11.2 0.0 0.33 10.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) adh_short PF00106.25 EWM30471.1 - 3.9e-45 153.7 0.0 5e-45 153.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EWM30471.1 - 1.7e-22 80.2 0.1 2.2e-22 79.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM30471.1 - 9.6e-13 48.4 0.0 1.6e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EWM30471.1 - 0.0022 17.9 0.8 0.012 15.5 0.1 2.3 3 0 0 3 3 3 1 NAD(P)H-binding Epimerase PF01370.21 EWM30471.1 - 0.091 12.2 0.0 0.15 11.5 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EWM30471.1 - 0.14 11.5 0.0 0.3 10.4 0.0 1.6 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) UAA PF08449.11 EWM30472.1 - 1.5e-65 221.4 6.7 1.8e-65 221.2 6.7 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EWM30472.1 - 3.5e-06 27.2 20.8 0.00023 21.4 11.5 2.3 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 EWM30472.1 - 2e-05 23.7 4.4 0.01 14.8 0.0 2.2 1 1 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like Nuc_sug_transp PF04142.15 EWM30472.1 - 0.0005 19.3 4.1 0.00065 19.0 4.1 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter SLC35F PF06027.12 EWM30472.1 - 0.033 13.7 3.3 0.051 13.1 3.3 1.3 1 0 0 1 1 1 0 Solute carrier family 35 TPT PF03151.16 EWM30472.1 - 0.094 12.0 6.3 0.34 10.2 6.2 1.8 1 1 0 1 1 1 0 Triose-phosphate Transporter family PNTB PF02233.16 EWM30473.1 - 2.8e-169 563.9 19.8 2.8e-169 563.9 19.8 2.0 2 0 0 2 2 2 2 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 EWM30473.1 - 2.3e-39 134.9 0.0 2.3e-39 134.9 0.0 3.0 5 0 0 5 5 5 1 Alanine dehydrogenase/PNT, C-terminal domain PNTB_4TM PF12769.7 EWM30473.1 - 1e-25 90.0 5.2 1e-25 90.0 5.2 3.8 4 0 0 4 4 4 1 4TM region of pyridine nucleotide transhydrogenase, mitoch TPP_enzyme_M PF00205.22 EWM30473.1 - 2.1e-08 34.0 0.1 1.2e-07 31.5 0.1 2.4 1 1 1 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Peptidase_M24 PF00557.24 EWM30474.1 - 3.1e-55 187.1 0.1 3.7e-55 186.8 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 FAM92 PF06730.11 EWM30475.1 - 1.2e-07 31.3 6.1 1.5e-07 31.1 6.1 1.1 1 0 0 1 1 1 1 FAM92 protein Vps5 PF09325.10 EWM30475.1 - 7.7e-05 22.4 6.0 0.00011 21.8 0.7 2.3 3 0 0 3 3 3 2 Vps5 C terminal like FA_desaturase_2 PF03405.14 EWM30476.1 - 5.4e-132 439.6 0.0 6.1e-132 439.4 0.0 1.0 1 0 0 1 1 1 1 Fatty acid desaturase Phenol_Hydrox PF02332.18 EWM30476.1 - 0.014 15.0 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Methane/Phenol/Toluene Hydroxylase DUF2213 PF09979.9 EWM30476.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2213) Rubrerythrin PF02915.17 EWM30476.1 - 0.15 12.5 0.0 25 5.3 0.0 2.3 2 0 0 2 2 2 0 Rubrerythrin PH PF00169.29 EWM30477.1 - 5.5e-09 36.5 0.2 1.4e-08 35.2 0.2 1.8 1 0 0 1 1 1 1 PH domain FAA_hydro_N_2 PF18288.1 EWM30477.1 - 0.044 14.2 0.1 0.26 11.8 0.1 2.5 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal domain 2 Lzipper-MIP1 PF14389.6 EWM30477.1 - 0.37 11.1 12.6 1 9.7 0.0 5.0 4 1 0 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 DUF4549 PF15082.6 EWM30477.1 - 1.9 8.3 5.5 2.3 8.0 0.9 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4549) GlcNAc PF11397.8 EWM30478.1 - 2.7e-68 231.0 0.1 1.1e-66 225.7 0.1 2.1 1 1 0 1 1 1 1 Glycosyltransferase (GlcNAc) UDPGP PF01704.18 EWM30479.1 - 7.5e-155 515.6 0.0 8.6e-155 515.4 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Rubis-subs-bind PF09273.11 EWM30480.1 - 8.9e-16 58.8 0.0 1.4e-15 58.1 0.0 1.3 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 EWM30480.1 - 3.7e-07 30.7 0.0 1.1e-06 29.2 0.0 1.8 2 0 0 2 2 2 1 SET domain Ish1 PF10281.9 EWM30480.1 - 0.15 12.4 0.0 6.2 7.2 0.0 2.6 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Fez1 PF06818.15 EWM30482.1 - 0.22 11.9 15.8 0.84 10.0 6.8 2.9 3 0 0 3 3 3 0 Fez1 Rx_N PF18052.1 EWM30482.1 - 1 9.7 4.2 6.4 7.1 0.2 3.0 2 0 0 2 2 2 0 Rx N-terminal domain dCMP_cyt_deam_1 PF00383.23 EWM30484.1 - 5.5e-23 80.8 0.4 1e-22 79.9 0.4 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EWM30484.1 - 3.3e-22 78.7 0.0 4.7e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase Inv-AAD PF18785.1 EWM30484.1 - 8.1e-06 25.7 0.6 0.00089 19.1 0.2 2.2 1 1 1 2 2 2 2 Invertebrate-AID/APOBEC-deaminase Bd3614-deam PF14439.6 EWM30484.1 - 0.00015 21.8 2.5 0.0016 18.5 2.5 2.1 1 1 0 1 1 1 1 Bd3614-like deaminase SNAD4 PF18750.1 EWM30484.1 - 0.0069 16.5 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC_N PF08210.11 EWM30484.1 - 0.012 15.5 0.0 0.027 14.4 0.0 1.4 1 1 0 1 1 1 0 APOBEC-like N-terminal domain NAD2 PF18782.1 EWM30484.1 - 0.065 13.4 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 APOBEC2 PF18772.1 EWM30484.1 - 0.074 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 APOBEC2 adh_short PF00106.25 EWM30487.1 - 2.1e-29 102.4 0.9 1e-25 90.4 0.1 2.4 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EWM30487.1 - 1.3e-20 73.9 0.4 9.2e-18 64.7 0.0 2.4 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM30487.1 - 1.5e-08 34.7 0.1 2.8e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EWM30487.1 - 0.013 15.0 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EWM30487.1 - 0.027 13.9 0.0 0.041 13.3 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 EWM30488.1 - 2.1e-29 102.4 0.9 1e-25 90.4 0.1 2.4 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EWM30488.1 - 1.3e-20 73.9 0.4 9.2e-18 64.7 0.0 2.4 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EWM30488.1 - 1.5e-08 34.7 0.1 2.8e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EWM30488.1 - 0.013 15.0 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EWM30488.1 - 0.027 13.9 0.0 0.041 13.3 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase UPF0054 PF02130.17 EWM30489.1 - 6.6e-30 103.5 0.0 6.6e-30 103.5 0.0 2.6 2 2 1 3 3 2 1 Uncharacterized protein family UPF0054 SDA1 PF05285.12 EWM30489.1 - 0.0063 16.0 18.2 0.0092 15.4 18.2 1.2 1 0 0 1 1 1 1 SDA1 PVL_ORF50 PF07768.11 EWM30489.1 - 0.087 13.1 5.2 0.24 11.7 5.2 1.7 1 0 0 1 1 1 0 PVL ORF-50-like family PPP4R2 PF09184.11 EWM30489.1 - 0.1 12.1 16.0 0.16 11.5 16.0 1.2 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 EWM30489.1 - 0.15 11.4 13.9 0.29 10.4 13.9 1.4 1 0 0 1 1 1 0 NOA36 protein BUD22 PF09073.10 EWM30489.1 - 0.23 10.7 16.0 0.35 10.2 16.0 1.2 1 0 0 1 1 1 0 BUD22 PA26 PF04636.13 EWM30489.1 - 0.78 8.6 7.3 1.1 8.1 7.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DGF-1_C PF11040.8 EWM30489.1 - 0.99 9.4 5.8 67 3.6 5.8 2.7 1 1 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Nop14 PF04147.12 EWM30489.1 - 2 6.5 20.9 2.8 6.0 20.9 1.1 1 0 0 1 1 1 0 Nop14-like family Nop25 PF09805.9 EWM30489.1 - 2.4 8.6 20.4 5.9 7.4 20.4 1.6 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) RNA_pol_3_Rpc31 PF11705.8 EWM30489.1 - 3.6 7.8 22.7 5.2 7.2 20.1 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Presenilin PF01080.17 EWM30489.1 - 3.9 6.2 6.4 5.3 5.7 6.4 1.1 1 0 0 1 1 1 0 Presenilin TFB6 PF17110.5 EWM30489.1 - 4.3 7.0 12.4 8 6.2 12.4 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DNA_pol_phi PF04931.13 EWM30489.1 - 5.4 5.0 20.8 8.7 4.3 20.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi Radical_SAM PF04055.21 EWM30490.1 - 2.1e-10 41.2 0.0 3.2e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily WD40 PF00400.32 EWM30491.1 - 2.7e-59 195.7 3.5 3.6e-07 30.8 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM30491.1 - 1.3e-17 63.9 0.0 0.0064 16.8 0.0 5.9 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EWM30491.1 - 1.8e-05 23.8 0.3 1.8 7.4 0.0 5.2 1 1 6 7 7 7 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EWM30491.1 - 6.3e-05 21.8 2.1 0.17 10.5 0.0 3.4 1 1 2 3 3 3 3 Nucleoporin Nup120/160 eIF2A PF08662.11 EWM30491.1 - 0.00016 21.6 0.0 0.016 15.1 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 EWM30491.1 - 0.017 13.5 0.0 0.13 10.5 0.0 2.3 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 EWM30491.1 - 0.068 12.5 0.0 16 4.7 0.0 3.2 2 2 1 3 3 3 0 WD40-like domain Hira PF07569.11 EWM30491.1 - 0.11 12.2 0.0 0.81 9.4 0.0 2.4 3 1 1 4 4 4 0 TUP1-like enhancer of split VHL PF01847.16 EWM30492.1 - 0.018 15.0 0.0 0.04 13.8 0.0 1.6 1 0 0 1 1 1 0 VHL beta domain DUF2764 PF10962.8 EWM30492.1 - 0.072 12.6 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2764) TT_ORF1 PF02956.14 EWM30493.1 - 2.2 6.8 7.4 2.3 6.8 7.4 1.0 1 0 0 1 1 1 0 TT viral orf 1 TFIIA PF03153.13 EWM30494.1 - 0.039 14.0 31.5 0.053 13.5 31.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med3 PF11593.8 EWM30494.1 - 2.6 7.1 15.7 4 6.5 15.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal ATG16 PF08614.11 EWM30494.1 - 4.4 7.5 27.2 11 6.1 27.2 1.7 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DnaJ_C PF01556.18 EWM30495.1 - 1.4e-32 112.9 0.0 1.9e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EWM30495.1 - 6.8e-23 80.6 0.7 1.2e-22 79.7 0.7 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EWM30495.1 - 0.0074 16.6 4.6 0.015 15.6 4.6 1.5 1 0 0 1 1 1 1 DnaJ central domain TB PF00683.17 EWM30495.1 - 0.045 13.5 1.2 0.088 12.6 1.2 1.4 1 0 0 1 1 1 0 TB domain DUF4336 PF14234.6 EWM30496.1 - 2.2e-19 69.8 0.0 1.8e-16 60.3 0.0 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4336) Chloroa_b-bind PF00504.21 EWM30498.1 - 1.9e-33 116.2 0.1 2.6e-33 115.8 0.1 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein TTL PF03133.15 EWM30499.1 - 2.6e-40 138.4 0.0 4.5e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family CAF1 PF04857.20 EWM30500.1 - 8.7e-77 258.4 0.0 1.2e-76 257.9 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.20 EWM30500.1 - 0.0033 17.1 0.0 0.95 9.1 0.0 2.3 2 0 0 2 2 2 2 3'-5' exonuclease RNA_bind PF08675.11 EWM30500.1 - 0.009 16.0 0.0 0.026 14.6 0.0 1.7 2 0 0 2 2 2 1 RNA binding domain Ank_2 PF12796.7 EWM30501.1 - 4.7e-30 104.0 0.0 9.8e-11 42.1 0.0 3.7 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EWM30501.1 - 5.5e-29 100.2 0.3 2.1e-10 40.9 0.0 4.7 3 1 1 4 4 4 4 Ankyrin repeats (many copies) DHHC PF01529.20 EWM30501.1 - 1e-25 90.4 17.4 5.5e-25 88.0 17.4 2.1 1 1 0 1 1 1 1 DHHC palmitoyltransferase Ank_5 PF13857.6 EWM30501.1 - 1.7e-23 82.4 2.9 1.6e-09 37.8 0.1 5.7 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EWM30501.1 - 1.2e-22 77.6 0.1 0.00027 21.1 0.0 7.7 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 EWM30501.1 - 2.5e-21 75.1 1.4 0.00018 21.8 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat 2-Hacid_dh_C PF02826.19 EWM30503.1 - 5.1e-61 205.1 0.0 1.2e-60 203.9 0.0 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EWM30503.1 - 1.5e-31 108.8 0.0 2.3e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 EWM30503.1 - 4.1e-09 36.0 0.1 2.7e-08 33.4 0.0 2.4 2 0 0 2 2 2 1 ACT domain IlvN PF07991.12 EWM30503.1 - 0.00068 19.2 0.0 0.0015 18.1 0.0 1.6 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 EWM30503.1 - 0.004 17.3 0.0 0.02 15.1 0.0 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 EWM30503.1 - 0.0091 16.1 0.1 0.042 13.9 0.0 2.1 2 1 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT_4 PF13291.6 EWM30503.1 - 0.012 16.2 0.0 0.036 14.7 0.0 1.8 1 0 0 1 1 1 0 ACT domain Aminotran_5 PF00266.19 EWM30504.1 - 7.9e-24 84.3 0.0 4.1e-18 65.5 0.0 3.2 1 1 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.16 EWM30504.1 - 7.7e-22 77.4 0.0 1.6e-21 76.4 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 EWM30504.1 - 8.3e-17 61.4 0.0 1.5e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 MOSC domain NifU PF01106.17 EWM30504.1 - 0.093 12.9 0.2 0.43 10.8 0.1 2.1 2 0 0 2 2 2 0 NifU-like domain SNF2_N PF00176.23 EWM30505.1 - 3.9e-49 167.3 0.0 6.6e-49 166.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EWM30505.1 - 7.6e-18 64.9 0.0 2.1e-17 63.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EWM30505.1 - 1e-05 25.6 0.0 3.1e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EWM30505.1 - 5.4e-05 23.0 0.0 9.8e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase APC_u14 PF16635.5 EWM30505.1 - 0.027 15.0 1.3 0.027 15.0 1.3 2.3 2 0 0 2 2 2 0 Unstructured region on APC between SAMP and APC_crr Lipase_3 PF01764.25 EWM30506.1 - 1.8e-13 50.6 0.0 3.2e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EWM30506.1 - 0.00037 21.2 0.1 0.00037 21.2 0.1 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EWM30506.1 - 0.074 13.2 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Thioesterase domain Cutinase PF01083.22 EWM30506.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Cutinase ParA PF10609.9 EWM30507.1 - 1.2e-87 293.4 0.1 9e-80 267.7 0.2 2.1 2 0 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EWM30507.1 - 1.2e-12 48.0 0.0 1e-11 45.0 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EWM30507.1 - 1.8e-08 34.5 0.0 2.6e-07 30.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 EWM30507.1 - 5.4e-07 29.1 0.1 6.5e-06 25.5 0.1 2.3 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.6 EWM30507.1 - 8.7e-06 25.4 0.0 1.6e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EWM30507.1 - 0.0004 20.3 0.5 0.00062 19.7 0.5 1.2 1 0 0 1 1 1 1 NACHT domain MipZ PF09140.11 EWM30507.1 - 0.00043 19.7 0.0 0.0013 18.0 0.0 1.8 1 1 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.6 EWM30507.1 - 0.0085 15.9 0.1 16 5.2 0.0 3.5 3 1 1 4 4 4 0 AAA domain RsgA_GTPase PF03193.16 EWM30507.1 - 0.029 14.3 0.1 0.14 12.0 0.1 2.0 2 0 0 2 2 2 0 RsgA GTPase DnaB_C PF03796.15 EWM30507.1 - 0.031 13.6 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain SRP54 PF00448.22 EWM30507.1 - 0.037 13.7 0.2 0.089 12.4 0.1 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 EWM30507.1 - 0.049 12.8 0.1 0.081 12.1 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain TsaE PF02367.17 EWM30507.1 - 0.052 13.5 0.1 0.089 12.8 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 EWM30507.1 - 0.22 11.2 0.0 0.39 10.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein ubiquitin PF00240.23 EWM30508.1 - 5.6e-17 61.3 0.0 8.3e-17 60.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EWM30508.1 - 0.0016 18.2 0.0 0.0027 17.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 EWM30508.1 - 0.0028 17.8 0.0 0.005 16.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EWM30508.1 - 0.011 16.2 0.0 0.026 15.0 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin-like domain ubiquitin PF00240.23 EWM30509.1 - 5.5e-17 61.3 0.0 8.3e-17 60.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 EWM30509.1 - 0.0016 18.5 0.0 0.005 16.9 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.8 EWM30509.1 - 0.0016 18.2 0.0 0.0027 17.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EWM30509.1 - 0.011 16.2 0.0 0.026 15.0 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-like domain ArfGap PF01412.18 EWM30510.1 - 2.3e-33 114.7 0.0 4.6e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Peptidase_M24 PF00557.24 EWM30511.1 - 6.8e-46 156.6 0.3 1.8e-45 155.2 0.1 1.8 2 0 0 2 2 2 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 EWM30511.1 - 3.2e-39 134.6 0.0 1.5e-38 132.5 0.0 2.2 3 1 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 EWM30511.1 - 9.5e-24 83.3 0.6 2.8e-23 81.7 0.1 2.1 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 EWM30511.1 - 8.2e-18 65.3 0.0 4.5e-15 56.5 0.0 3.0 2 1 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Pam16 PF03656.13 EWM30512.1 - 4e-23 81.8 1.8 5.1e-23 81.5 1.8 1.1 1 0 0 1 1 1 1 Pam16 Acid_PPase PF12689.7 EWM30512.1 - 0.042 13.7 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 Acid Phosphatase DUF5635 PF18685.1 EWM30512.1 - 0.12 12.4 0.4 0.49 10.4 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5635) Thioredoxin PF00085.20 EWM30513.1 - 2.7e-29 101.2 0.1 3e-29 101.0 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EWM30513.1 - 6.8e-07 29.5 0.0 1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EWM30513.1 - 3.4e-06 27.0 0.0 3.8e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 EWM30513.1 - 7.6e-06 26.3 0.3 5.6e-05 23.5 0.3 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 EWM30513.1 - 2.4e-05 24.1 0.1 2.8e-05 23.9 0.1 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.6 EWM30513.1 - 0.0004 20.5 0.1 0.00076 19.6 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 EWM30513.1 - 0.002 17.6 0.0 0.0022 17.4 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 EWM30513.1 - 0.0021 17.8 0.0 0.0024 17.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.24 EWM30513.1 - 0.019 15.2 0.2 0.027 14.7 0.2 1.4 1 1 0 1 1 1 0 Glutaredoxin PDZ PF00595.24 EWM30514.1 - 0.0019 18.5 0.0 0.0044 17.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Ribosomal_L2_C PF03947.18 EWM30514.1 - 0.06 13.5 0.9 1.6 8.9 0.1 2.2 2 0 0 2 2 2 0 Ribosomal Proteins L2, C-terminal domain DHHC PF01529.20 EWM30515.1 - 1.6e-30 105.9 6.5 1.6e-30 105.9 6.5 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase CCSMST1 PF15013.6 EWM30515.1 - 0.035 14.3 0.8 0.15 12.2 0.1 2.3 2 0 0 2 2 2 0 CCSMST1 family IGFBP PF00219.18 EWM30515.1 - 0.71 10.6 6.7 1.6 9.4 6.7 1.5 1 0 0 1 1 1 0 Insulin-like growth factor binding protein Response_reg PF00072.24 EWM30516.1 - 1.2e-20 73.8 0.2 2e-20 73.0 0.2 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 EWM30516.1 - 4.4e-16 59.4 0.0 4.1e-08 33.7 0.0 2.5 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EWM30516.1 - 2.8e-12 46.5 0.0 6e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain SDA1 PF05285.12 EWM30516.1 - 0.02 14.3 19.9 0.042 13.3 19.9 1.4 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EWM30516.1 - 0.1 10.8 20.1 0.16 10.2 20.1 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_pol_3_Rpc31 PF11705.8 EWM30516.1 - 0.12 12.7 17.3 0.21 11.8 17.3 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Sporozoite_P67 PF05642.11 EWM30516.1 - 2.4 6.1 6.4 4.5 5.2 6.4 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RR_TM4-6 PF06459.12 EWM30516.1 - 2.9 7.7 7.3 5.1 6.9 7.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1269 PF06897.12 EWM30517.1 - 0.0047 17.2 1.0 0.01 16.1 0.6 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1269) DUF5339 PF17274.2 EWM30517.1 - 0.061 14.2 0.9 0.12 13.2 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5339) Syntaxin-6_N PF09177.11 EWM30517.1 - 0.25 11.9 3.6 0.63 10.6 3.6 1.7 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Seryl_tRNA_N PF02403.22 EWM30517.1 - 0.33 11.2 6.0 2.8 8.2 0.7 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain tRNA-synt_1e PF01406.19 EWM30518.1 - 1.3e-106 356.4 0.0 1.7e-106 356.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DALR_2 PF09190.11 EWM30518.1 - 2.1e-11 44.1 0.0 4.9e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 DALR domain tRNA-synt_1g PF09334.11 EWM30518.1 - 5e-11 42.0 0.0 0.00015 20.6 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1f PF01921.18 EWM30518.1 - 6.2e-05 22.1 0.0 0.18 10.7 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (K) CS PF04969.16 EWM30519.1 - 1.4e-18 67.7 0.0 2.8e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 CS domain Nudc_N PF14050.6 EWM30519.1 - 7e-15 54.8 0.0 1.7e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. XRN_M PF17846.1 EWM30519.1 - 0.41 9.5 5.2 0.034 13.1 0.7 1.4 2 0 0 2 2 2 0 Xrn1 helical domain Fer4_13 PF13370.6 EWM30520.1 - 3.4e-10 40.3 0.0 5.8e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 EWM30520.1 - 4.4e-07 30.5 0.1 1.2e-06 29.1 0.1 1.8 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_2 PF12797.7 EWM30520.1 - 0.0026 17.7 3.2 0.0059 16.6 3.2 1.5 1 0 0 1 1 1 1 4Fe-4S binding domain Fer4_4 PF12800.7 EWM30520.1 - 0.0054 17.2 1.3 0.0054 17.2 1.3 1.6 2 0 0 2 2 1 1 4Fe-4S binding domain Fer4_7 PF12838.7 EWM30520.1 - 0.0065 17.0 0.2 0.13 12.9 0.1 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 EWM30520.1 - 0.0065 16.6 1.4 0.016 15.3 1.4 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 EWM30520.1 - 0.01 16.0 0.5 0.033 14.4 0.2 1.9 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4 PF00037.27 EWM30520.1 - 0.014 15.2 6.2 0.077 12.8 3.5 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 EWM30520.1 - 0.015 15.9 0.3 0.044 14.3 0.2 1.8 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 EWM30520.1 - 0.023 15.5 0.2 0.044 14.6 0.2 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 EWM30520.1 - 0.025 15.0 0.1 0.055 13.9 0.1 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 EWM30520.1 - 0.071 14.1 0.5 0.58 11.1 0.2 2.2 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 EWM30520.1 - 0.09 12.9 0.6 0.09 12.9 0.6 1.5 2 0 0 2 2 1 0 4Fe-4S dicluster domain Lactamase_B_5 PF14597.6 EWM30520.1 - 0.19 11.2 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Fer4_6 PF12837.7 EWM30520.1 - 3.6 7.8 6.5 5.1 7.3 2.8 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 EWM30520.1 - 7.4 7.8 6.9 4.9 8.3 3.8 2.0 2 0 0 2 2 2 0 4Fe-4S binding domain DEAD PF00270.29 EWM30521.1 - 6.8e-46 156.2 0.0 1.5e-45 155.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EWM30521.1 - 5.6e-26 91.1 0.0 4.1e-25 88.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EWM30521.1 - 0.003 17.6 0.0 0.0049 16.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EWM30521.1 - 0.11 12.8 0.0 0.64 10.3 0.0 2.3 1 1 0 1 1 1 0 AAA domain TFB6 PF17110.5 EWM30521.1 - 0.12 12.1 0.4 0.26 11.0 0.4 1.6 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH FUSC PF04632.12 EWM30522.1 - 3e-10 39.3 5.1 3e-10 39.3 5.1 2.6 3 0 0 3 3 3 1 Fusaric acid resistance protein family FUSC_2 PF13515.6 EWM30522.1 - 1.2e-07 31.8 12.2 1.2e-07 31.8 12.2 2.5 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 EWM30522.1 - 2.2e-06 26.8 12.1 4.4e-06 25.8 9.6 2.4 2 1 0 2 2 2 1 Aluminium activated malate transporter Rick_17kDa_Anti PF05433.15 EWM30522.1 - 0.14 12.1 0.2 0.3 11.0 0.2 1.6 1 0 0 1 1 1 0 Glycine zipper 2TM domain DUF547 PF04784.14 EWM30523.1 - 1.4e-22 80.0 0.0 7.3e-22 77.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF547 YL1 PF05764.13 EWM30523.1 - 0.00053 20.2 5.1 0.00053 20.2 5.1 2.3 2 0 0 2 2 2 1 YL1 nuclear protein PH PF00169.29 EWM30523.1 - 0.057 13.9 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 PH domain DUF2052 PF09747.9 EWM30523.1 - 4.8 7.3 16.8 0.04 14.1 7.2 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) N-SET PF11764.8 EWM30523.1 - 6.6 6.8 9.2 13 5.9 9.2 1.3 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N RR_TM4-6 PF06459.12 EWM30523.1 - 8.4 6.1 8.8 19 5.0 8.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4692 PF15763.5 EWM30524.1 - 0.021 15.3 0.2 0.06 13.8 0.0 1.8 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) DUF3328 PF11807.8 EWM30524.1 - 0.15 11.8 0.1 0.26 11.0 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) HAD_2 PF13419.6 EWM30525.1 - 3.7e-13 49.9 0.0 5.4e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EWM30525.1 - 1.1e-05 25.8 0.0 2.4e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EWM30525.1 - 0.00026 21.0 0.0 0.00051 20.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like SNARE PF05739.19 EWM30526.1 - 2.3e-13 49.9 1.1 2.3e-13 49.9 1.1 2.1 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.25 EWM30526.1 - 0.00012 21.8 5.0 0.00092 18.9 0.8 2.4 2 0 0 2 2 2 2 Syntaxin DSPc PF00782.20 EWM30527.1 - 1.3e-28 99.5 0.0 2.5e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EWM30527.1 - 0.0025 18.1 0.0 0.0055 17.0 0.0 1.6 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 EWM30527.1 - 0.054 13.1 0.6 0.37 10.3 0.0 2.2 2 0 0 2 2 2 0 Protein-tyrosine phosphatase Cofac_haem_bdg PF04187.13 EWM30528.1 - 3.6e-52 177.5 0.8 4.5e-52 177.1 0.8 1.1 1 0 0 1 1 1 1 Haem-binding uptake, Tiki superfamily, ChaN Erythro_esteras PF05139.14 EWM30528.1 - 0.037 13.8 0.1 0.11 12.3 0.1 1.5 1 1 0 1 1 1 0 Erythromycin esterase GFA PF04828.14 EWM30529.1 - 0.0065 16.8 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme AMP-binding PF00501.28 EWM30530.1 - 1.5e-42 145.7 0.0 2.1e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme RRM_1 PF00076.22 EWM30531.1 - 8.1e-17 60.8 0.0 1.7e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Vir_act_alpha_C PF10400.9 EWM30531.1 - 0.016 15.8 0.5 0.03 15.0 0.2 1.6 2 0 0 2 2 2 0 Virulence activator alpha C-term ING PF12998.7 EWM30531.1 - 0.068 13.8 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding CDC27 PF09507.10 EWM30531.1 - 0.43 9.9 5.8 0.52 9.6 5.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Cwf_Cwc_15 PF04889.12 EWM30531.1 - 4 7.1 8.9 5.3 6.7 8.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4175 PF13779.6 EWM30531.1 - 9.3 4.0 15.0 12 3.7 15.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) NAD_binding_10 PF13460.6 EWM30532.1 - 1.4e-33 116.3 0.0 2e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EWM30532.1 - 8.4e-08 32.0 0.5 0.00083 19.0 0.0 2.4 2 1 0 2 2 2 2 NmrA-like family 3Beta_HSD PF01073.19 EWM30532.1 - 1.2e-06 27.8 0.0 0.001 18.1 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EWM30532.1 - 2.9e-06 26.9 0.0 0.0019 17.7 0.0 2.5 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 EWM30532.1 - 0.00086 19.4 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 EWM30532.1 - 0.0013 17.9 0.0 0.14 11.3 0.0 2.2 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 EWM30532.1 - 0.0025 18.2 0.1 0.02 15.3 0.0 2.2 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.18 EWM30532.1 - 0.0083 16.4 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain WD40 PF00400.32 EWM30533.1 - 1e-42 143.3 16.0 5.8e-11 42.8 1.2 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 EWM30533.1 - 1.5e-32 112.5 0.1 2.1e-32 112.1 0.1 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 EWM30533.1 - 8.1e-12 45.3 0.1 0.015 15.6 0.0 4.8 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EWM30533.1 - 0.00082 19.3 0.0 0.02 14.8 0.0 2.3 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EWM30533.1 - 0.0024 16.6 0.1 0.51 8.9 0.0 2.5 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EWM30533.1 - 0.0033 16.4 0.0 14 4.5 0.0 4.0 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 EWM30533.1 - 0.061 12.6 1.4 13 5.0 0.0 3.4 2 1 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal LZ_Tnp_IS481 PF13011.6 EWM30533.1 - 0.1 13.1 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 LisH PF08513.11 EWM30533.1 - 0.18 11.8 0.1 6.2 6.9 0.0 2.5 2 0 0 2 2 2 0 LisH Arm PF00514.23 EWM30534.1 - 3.9e-07 29.9 1.1 0.0014 18.6 0.0 4.2 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 EWM30534.1 - 0.034 14.2 0.0 0.93 9.6 0.0 2.8 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain PE_PPE_C PF12484.8 EWM30534.1 - 1.1 10.2 5.9 26 5.8 5.9 2.6 1 1 0 1 1 1 0 Polymorphic PE/PPE proteins C terminal RRM_1 PF00076.22 EWM30536.1 - 9.2e-21 73.5 0.0 5.4e-14 51.8 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EWM30536.1 - 0.021 14.4 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HEAT PF02985.22 EWM30537.1 - 6.8e-07 29.0 0.6 0.97 9.9 0.0 5.2 5 0 0 5 5 5 3 HEAT repeat WD40 PF00400.32 EWM30537.1 - 0.00044 21.0 11.0 2 9.4 0.0 7.6 8 0 0 8 8 8 1 WD domain, G-beta repeat HEAT_2 PF13646.6 EWM30537.1 - 0.0024 18.2 0.0 0.54 10.7 0.0 3.4 3 0 0 3 3 3 1 HEAT repeats ANAPC4_WD40 PF12894.7 EWM30537.1 - 0.025 14.9 0.0 48 4.4 0.0 4.1 4 1 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain HEAT_EZ PF13513.6 EWM30537.1 - 0.039 14.5 0.2 0.82 10.2 0.0 3.4 4 0 0 4 4 4 0 HEAT-like repeat ANAPC5 PF12862.7 EWM30538.1 - 2.6e-24 85.1 1.9 1.1e-23 83.1 0.3 2.7 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.6 EWM30538.1 - 9.1e-05 22.7 17.4 0.0081 16.4 2.2 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EWM30538.1 - 0.025 15.4 0.4 0.025 15.4 0.4 6.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Ank_2 PF12796.7 EWM30539.1 - 9.5e-07 29.3 0.1 2.2e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EWM30539.1 - 0.00061 20.1 0.2 0.0046 17.4 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 EWM30539.1 - 0.0017 18.9 0.0 0.0042 17.6 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EWM30539.1 - 0.0091 16.4 0.1 0.057 14.0 0.0 2.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 EWM30539.1 - 0.19 12.1 0.1 0.9 9.9 0.0 2.1 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Syntaxin PF00804.25 EWM30540.1 - 4.3e-39 134.3 6.6 5.5e-39 133.9 6.6 1.1 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 EWM30540.1 - 6.1e-10 38.9 0.5 1.5e-09 37.7 0.5 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 EWM30540.1 - 8.4e-05 22.9 6.6 0.0013 19.1 4.9 2.8 1 1 2 3 3 3 1 Syntaxin-like protein SCP-1 PF05483.12 EWM30540.1 - 0.0019 16.3 0.6 0.0019 16.3 0.6 1.5 2 0 0 2 2 2 1 Synaptonemal complex protein 1 (SCP-1) Rbsn PF11464.8 EWM30540.1 - 0.0031 17.2 0.4 1 9.2 0.2 2.7 2 0 0 2 2 2 2 Rabenosyn Rab binding domain T2SSF PF00482.23 EWM30540.1 - 0.017 15.1 1.6 0.13 12.2 0.2 2.7 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein F ATP-synt_S1 PF05827.12 EWM30540.1 - 0.088 12.6 0.2 0.15 11.8 0.2 1.4 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) PAH PF02671.21 EWM30540.1 - 0.13 12.5 1.7 0.4 10.8 1.7 1.9 1 1 0 1 1 1 0 Paired amphipathic helix repeat RGS PF00615.19 EWM30540.1 - 0.51 10.6 3.9 2 8.7 0.2 2.5 1 1 2 3 3 3 0 Regulator of G protein signaling domain UPF0242 PF06785.11 EWM30540.1 - 0.96 9.5 9.2 0.23 11.5 3.7 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF5344 PF17279.2 EWM30540.1 - 6.2 7.5 7.9 1.7 9.3 1.8 3.1 3 2 1 4 4 4 0 Family of unknown function (DUF5344) Malate_synthase PF01274.22 EWM30541.1 - 2.7e-71 240.4 0.0 3.9e-33 114.5 0.0 4.1 4 0 0 4 4 4 4 Malate synthase p450 PF00067.22 EWM30542.1 - 2.3e-70 237.7 0.0 2.8e-70 237.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_transf_34 PF05637.12 EWM30543.1 - 0.00043 20.1 0.0 0.001 18.9 0.0 1.6 2 0 0 2 2 2 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 EWM30543.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF273 GDP_Man_Dehyd PF16363.5 EWM30544.1 - 4.1e-68 230.2 0.1 1.3e-65 222.0 0.0 2.0 1 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EWM30544.1 - 1.3e-59 201.6 0.1 1.6e-59 201.3 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EWM30544.1 - 3.1e-21 75.8 0.0 4.2e-16 58.9 0.1 2.0 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EWM30544.1 - 3.4e-21 75.5 0.0 4.8e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EWM30544.1 - 7.8e-16 58.0 0.1 7.8e-15 54.7 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 EWM30544.1 - 8.5e-15 54.6 0.0 1.4e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EWM30544.1 - 0.00027 20.9 0.0 0.00043 20.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding WD40 PF00400.32 EWM30546.1 - 9.7e-13 48.4 1.3 1.4e-05 25.7 0.1 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EWM30546.1 - 4.9e-07 30.0 0.0 0.12 12.7 0.0 3.1 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain FKBP_C PF00254.28 EWM30547.1 - 4.5e-18 65.4 0.0 6.4e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Oxidored_FMN PF00724.20 EWM30548.1 - 7.2e-83 278.7 0.0 9.1e-83 278.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family 2-ph_phosp PF04029.14 EWM30548.1 - 0.094 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 2-phosphosulpholactate phosphatase PPR PF01535.20 EWM30549.1 - 1.8e-16 59.1 2.5 0.05 13.9 0.0 8.1 8 1 0 8 8 8 4 PPR repeat PPR_2 PF13041.6 EWM30549.1 - 1.5e-14 53.9 0.1 0.014 15.6 0.0 8.1 8 1 1 9 9 9 3 PPR repeat family PPR_3 PF13812.6 EWM30549.1 - 1.8e-06 27.9 0.0 0.0027 17.7 0.0 3.6 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 EWM30549.1 - 0.0016 18.1 0.0 8.9 6.1 0.0 5.0 5 0 0 5 5 5 1 PPR repeat Smr PF01713.21 EWM30549.1 - 0.17 12.2 1.7 0.7 10.3 1.7 2.1 1 1 0 1 1 1 0 Smr domain TPR_14 PF13428.6 EWM30549.1 - 0.19 12.6 6.5 19 6.4 0.4 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat CytochromB561_N PF09786.9 EWM30550.1 - 1.3e-10 41.0 0.0 5.4e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 Cytochrome B561, N terminal Kinesin PF00225.23 EWM30551.1 - 1.4e-85 287.2 0.0 1.9e-85 286.7 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EWM30551.1 - 5.4e-12 45.9 0.0 9.5e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding UPF0242 PF06785.11 EWM30551.1 - 0.0021 18.2 7.1 0.0038 17.4 1.3 2.3 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus Stathmin PF00836.19 EWM30551.1 - 1.7 8.6 7.2 1.1 9.2 4.2 2.2 2 0 0 2 2 2 0 Stathmin family MFS_1 PF07690.16 EWM30552.1 - 1e-28 100.3 31.6 1e-28 100.3 31.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_S49 PF01343.18 EWM30553.1 - 7.8e-26 90.9 0.0 1.2e-25 90.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S49 Peptidase_S49_N PF08496.10 EWM30553.1 - 3.6e-10 40.1 0.0 3.6e-10 40.1 0.0 2.4 2 0 0 2 2 1 1 Peptidase family S49 N-terminal DNA_pol_phi PF04931.13 EWM30553.1 - 1.8e-07 29.7 13.9 2.6e-07 29.2 13.9 1.2 1 0 0 1 1 1 1 DNA polymerase phi Nop14 PF04147.12 EWM30553.1 - 0.00026 19.4 23.4 0.00035 19.0 23.4 1.1 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 EWM30553.1 - 0.001 17.5 20.9 0.0014 17.0 20.9 1.1 1 0 0 1 1 1 1 CDC45-like protein Presenilin PF01080.17 EWM30553.1 - 0.0014 17.5 1.8 0.0022 16.8 1.8 1.3 1 0 0 1 1 1 1 Presenilin DUF4471 PF14740.6 EWM30553.1 - 0.0055 16.0 0.5 0.012 14.9 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) Mpp10 PF04006.12 EWM30553.1 - 0.049 12.1 28.8 0.068 11.6 28.8 1.1 1 0 0 1 1 1 0 Mpp10 protein SpoIIIAH PF12685.7 EWM30553.1 - 0.094 12.5 9.6 0.17 11.7 9.6 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein BUD22 PF09073.10 EWM30553.1 - 0.099 12.0 27.1 0.18 11.1 27.1 1.3 1 0 0 1 1 1 0 BUD22 Suf PF05843.14 EWM30553.1 - 0.099 12.6 2.1 0.17 11.8 2.1 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SDA1 PF05285.12 EWM30553.1 - 0.24 10.8 30.6 0.34 10.3 30.6 1.1 1 0 0 1 1 1 0 SDA1 ECH_1 PF00378.20 EWM30553.1 - 0.26 10.6 1.6 9.7 5.4 0.5 2.2 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase Connexin PF00029.19 EWM30553.1 - 0.3 10.8 2.0 0.52 10.0 2.0 1.5 1 0 0 1 1 1 0 Connexin Tim54 PF11711.8 EWM30553.1 - 0.4 9.4 9.8 0.71 8.6 9.8 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PPP4R2 PF09184.11 EWM30553.1 - 0.84 9.2 24.8 1.4 8.4 24.8 1.3 1 0 0 1 1 1 0 PPP4R2 RNA_pol_Rpc4 PF05132.14 EWM30553.1 - 1.5 9.3 11.2 3.7 8.0 11.2 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 RNA_polI_A34 PF08208.11 EWM30553.1 - 1.5 8.9 16.7 3.4 7.7 16.7 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 NPR3 PF03666.13 EWM30553.1 - 2.1 7.1 14.4 3 6.5 14.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.12 EWM30553.1 - 2.2 8.0 16.8 3.6 7.3 16.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAPS PF04499.15 EWM30553.1 - 2.5 6.8 12.1 3.6 6.3 12.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CCSAP PF15748.5 EWM30553.1 - 3.4 7.8 17.0 0.13 12.5 11.3 1.5 2 0 0 2 2 1 0 Centriole, cilia and spindle-associated CDC27 PF09507.10 EWM30553.1 - 6.5 6.0 20.6 12 5.1 20.6 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF913 PF06025.12 EWM30553.1 - 8.3 5.3 9.9 14 4.5 9.9 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Zip PF02535.22 EWM30553.1 - 9 5.4 13.2 16 4.6 13.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1754 PF08555.10 EWM30555.1 - 1.8e-05 25.4 11.7 1.8e-05 25.4 11.7 1.5 1 1 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) IFRD PF05004.13 EWM30555.1 - 9.9 5.2 9.9 0.041 13.0 1.2 1.4 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) Sel1 PF08238.12 EWM30556.1 - 0.032 14.9 1.5 0.16 12.7 0.0 2.6 2 0 0 2 2 2 0 Sel1 repeat Pro_isomerase PF00160.21 EWM30557.1 - 2.2e-06 28.1 0.0 4.1e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Exonuc_VII_L PF02601.15 EWM30557.1 - 0.099 12.2 0.5 0.17 11.4 0.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit SCFA_trans PF02667.14 EWM30557.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Short chain fatty acid transporter DUF3552 PF12072.8 EWM30557.1 - 0.17 11.3 9.5 0.24 10.8 9.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF4303 PF14136.6 EWM30557.1 - 0.19 11.5 1.5 0.29 10.8 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) OmpH PF03938.14 EWM30557.1 - 2.6 8.4 7.3 4.4 7.6 7.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) LmjF365940-deam PF14421.6 EWM30558.1 - 4.3e-56 189.6 0.0 1.4e-55 188.0 0.0 1.9 1 1 0 1 1 1 1 A distinct subfamily of CDD/CDA-like deaminases dCMP_cyt_deam_1 PF00383.23 EWM30558.1 - 0.044 13.7 0.0 0.88 9.5 0.0 2.4 2 0 0 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region bZIP_1 PF00170.21 EWM30559.1 - 0.00023 21.2 3.9 0.00047 20.2 3.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EWM30559.1 - 0.041 14.0 6.6 0.095 12.8 6.6 1.5 1 0 0 1 1 1 0 Basic region leucine zipper PAS_4 PF08448.10 EWM30559.1 - 0.05 13.9 0.0 0.19 12.0 0.0 2.0 1 0 0 1 1 1 0 PAS fold Nup192 PF11894.8 EWM30560.1 - 2.5e-39 134.4 0.0 8.9e-18 63.0 0.0 5.2 5 1 0 5 5 5 4 Nuclear pore complex scaffold, nucleoporins 186/192/205 UPF0242 PF06785.11 EWM30560.1 - 3.3 7.8 4.2 14 5.8 0.6 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus MFS_5 PF05631.14 EWM30562.1 - 3.1e-60 204.0 3.6 2.4e-46 158.3 1.0 2.3 2 0 0 2 2 2 2 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 EWM30562.1 - 5e-22 78.3 27.3 5e-22 78.3 27.3 2.0 3 0 0 3 3 3 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EWM30562.1 - 0.00026 20.0 4.9 0.003 16.5 0.1 3.0 2 1 1 3 3 3 2 MFS_1 like family SOG2 PF10428.9 EWM30566.1 - 0.13 11.5 0.2 0.19 10.9 0.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TTL PF03133.15 EWM30567.1 - 1.4e-31 109.7 0.0 2.2e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family zf-HIT PF04438.16 EWM30568.1 - 1.5e-06 27.9 13.4 1.5e-06 27.9 13.4 1.6 2 0 0 2 2 2 1 HIT zinc finger YL1_C PF08265.11 EWM30568.1 - 0.039 13.7 0.3 0.055 13.3 0.3 1.2 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain LCM PF04072.14 EWM30569.1 - 7.3e-17 61.9 0.0 1.1e-16 61.3 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase DUF4033 PF13225.6 EWM30570.1 - 4.2e-33 113.2 0.3 7.3e-33 112.4 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4033) DUF4033 PF13225.6 EWM30571.1 - 4.2e-33 113.2 0.3 7.3e-33 112.4 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4033) Cellulase PF00150.18 EWM30572.1 - 5e-06 26.1 0.0 1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MTCP1 PF08991.10 EWM30573.1 - 6.1e-11 42.4 8.5 9.4e-11 41.8 8.5 1.3 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type Methyltransf_24 PF13578.6 EWM30574.1 - 5.6e-07 30.5 0.0 1.5e-06 29.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Glyco_transf_34 PF05637.12 EWM30575.1 - 1.1e-20 74.4 0.2 3.8e-10 39.9 0.0 2.2 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 EWM30575.1 - 3.5e-07 30.0 0.0 5e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF273 Nucleotid_trans PF03407.16 EWM30575.1 - 5.3e-05 23.3 0.1 0.00011 22.3 0.0 1.6 2 0 0 2 2 2 1 Nucleotide-diphospho-sugar transferase TatD_DNase PF01026.21 EWM30576.1 - 7e-49 166.5 0.0 8.9e-49 166.2 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase HflK_N PF12221.8 EWM30576.1 - 0.2 11.7 0.0 0.45 10.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial membrane protein N terminal P5CR_dimer PF14748.6 EWM30577.1 - 4.3e-41 139.4 2.8 4.3e-41 139.4 2.8 1.9 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EWM30577.1 - 5.8e-19 68.5 1.5 1.1e-18 67.6 0.3 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EWM30577.1 - 0.0003 21.0 0.2 0.00066 19.9 0.2 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase PDH PF02153.17 EWM30577.1 - 0.00042 19.4 0.2 0.00078 18.5 0.2 1.4 1 0 0 1 1 1 1 Prephenate dehydrogenase Rossmann-like PF10727.9 EWM30577.1 - 0.00074 19.4 0.4 0.00074 19.4 0.4 2.7 3 0 0 3 3 3 1 Rossmann-like domain NAD_Gly3P_dh_N PF01210.23 EWM30577.1 - 0.0017 18.4 0.1 0.0035 17.3 0.1 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UPF0113_N PF17833.1 EWM30578.1 - 2.4e-30 104.9 0.1 3.6e-30 104.4 0.1 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 EWM30578.1 - 3.9e-21 75.1 0.0 6e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain HA2 PF04408.23 EWM30580.1 - 1.1e-22 80.3 0.1 2.1e-22 79.4 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EWM30580.1 - 1e-20 73.8 0.1 2.4e-20 72.7 0.1 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EWM30580.1 - 3.6e-11 43.4 0.0 7.7e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EWM30580.1 - 6.6e-08 32.5 0.2 1.7e-07 31.2 0.2 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.9 EWM30580.1 - 0.00048 19.5 0.0 0.00073 18.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 EWM30580.1 - 0.0014 18.4 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EWM30580.1 - 0.0018 18.5 0.1 0.0087 16.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 EWM30580.1 - 0.0051 16.8 0.1 0.01 15.8 0.1 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_19 PF13245.6 EWM30580.1 - 0.0085 16.4 0.1 0.017 15.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EWM30580.1 - 0.011 16.2 0.0 0.3 11.6 0.0 2.4 2 0 0 2 2 2 0 ABC transporter ATPase PF06745.13 EWM30580.1 - 0.021 14.2 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 EWM30580.1 - 0.023 15.1 0.1 0.15 12.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 EWM30580.1 - 0.033 13.2 0.1 0.1 11.6 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein ResIII PF04851.15 EWM30580.1 - 0.039 13.9 0.0 10 6.1 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EWM30580.1 - 0.047 13.4 0.0 1.6 8.4 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein SRP54 PF00448.22 EWM30580.1 - 0.14 11.8 0.2 0.44 10.2 0.2 1.8 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AIRC PF00731.20 EWM30581.1 - 5.1e-64 214.3 0.2 1.1e-63 213.2 0.2 1.6 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 EWM30581.1 - 6.8e-56 188.5 0.0 1.4e-55 187.5 0.0 1.5 2 0 0 2 2 2 1 ATP-grasp domain PurK_C PF17769.1 EWM30581.1 - 5.2e-18 64.5 0.1 1.4e-17 63.1 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 EWM30581.1 - 0.00074 19.1 0.0 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 EWM30581.1 - 0.0017 17.9 0.0 0.003 17.1 0.0 1.5 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 EWM30581.1 - 0.0063 16.6 0.0 0.012 15.7 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp domain 2-Hacid_dh_C PF02826.19 EWM30581.1 - 0.0079 15.6 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HHH PF00633.23 EWM30582.1 - 0.038 13.9 0.2 0.1 12.5 0.2 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif SopD PF11047.8 EWM30582.1 - 0.09 11.9 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Salmonella outer protein D Rcd1 PF04078.13 EWM30583.1 - 1.2e-123 411.5 3.7 1.4e-123 411.3 3.7 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Rcd1 PF04078.13 EWM30584.1 - 7.8e-124 412.1 3.7 8.9e-124 411.9 3.7 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Rcd1 PF04078.13 EWM30585.1 - 7.1e-120 399.1 1.9 7.9e-120 399.0 1.9 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Rcd1 PF04078.13 EWM30586.1 - 7.1e-120 399.1 1.9 7.9e-120 399.0 1.9 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Adaptin_N PF01602.20 EWM30587.1 - 6.9e-86 288.9 3.1 9.8e-86 288.4 3.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 EWM30587.1 - 1.4e-55 186.8 0.0 3.1e-55 185.6 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 EWM30587.1 - 7.3e-49 165.3 0.0 1.2e-48 164.5 0.0 1.4 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.6 EWM30587.1 - 3.1e-10 40.3 3.8 0.00012 22.4 0.0 4.3 3 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.7 EWM30587.1 - 4.7e-09 36.5 0.3 2.6e-07 30.8 0.0 2.7 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EWM30587.1 - 6.5e-05 22.9 1.3 0.27 11.6 0.0 4.4 3 0 0 3 3 3 2 HEAT repeat Arm PF00514.23 EWM30587.1 - 0.00015 21.7 0.1 0.083 13.0 0.0 3.6 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EWM30587.1 - 0.00045 20.6 2.1 1.9 9.1 0.1 4.3 4 0 0 4 4 4 2 HEAT-like repeat Coatomer_g_Cpla PF16381.5 EWM30587.1 - 0.0012 18.9 0.0 0.0029 17.7 0.0 1.6 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform Alpha_adaptinC2 PF02883.20 EWM30587.1 - 0.18 12.1 0.0 0.46 10.8 0.0 1.6 1 0 0 1 1 1 0 Adaptin C-terminal domain FAD_binding_3 PF01494.19 EWM30588.1 - 1e-63 215.7 0.0 2.8e-63 214.3 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 EWM30588.1 - 0.00092 18.4 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EWM30588.1 - 0.0017 17.7 0.7 0.033 13.4 0.1 2.7 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EWM30588.1 - 0.0029 17.3 0.1 0.031 13.8 0.1 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EWM30588.1 - 0.0034 16.7 0.0 0.0063 15.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 EWM30588.1 - 0.012 14.3 0.0 0.022 13.5 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 EWM30588.1 - 0.015 14.7 0.1 0.022 14.1 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EWM30588.1 - 0.02 15.1 0.0 0.054 13.7 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.10 EWM30588.1 - 0.024 13.7 0.3 3.9 6.4 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase AlaDh_PNT_C PF01262.21 EWM30588.1 - 0.038 13.3 0.0 0.06 12.6 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 EWM30588.1 - 0.058 12.6 0.0 0.093 12.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EWM30588.1 - 0.062 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glu_dehyd_C PF16912.5 EWM30588.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus DUF4560 PF15118.6 EWM30588.1 - 0.14 12.1 0.0 0.43 10.5 0.0 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4560) GIDA PF01134.22 EWM30588.1 - 0.14 11.2 0.2 0.2 10.7 0.2 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A BolA PF01722.18 EWM30589.1 - 7.7e-16 58.1 0.0 1.6e-15 57.1 0.0 1.5 1 1 0 1 1 1 1 BolA-like protein MMR_HSR1 PF01926.23 EWM30590.1 - 1.7e-17 63.5 0.2 2.1e-14 53.6 0.0 2.9 3 0 0 3 3 3 2 50S ribosome-binding GTPase GN3L_Grn1 PF08701.11 EWM30590.1 - 6.4e-16 58.2 19.2 6.4e-16 58.2 19.2 3.7 3 0 0 3 3 2 1 GNL3L/Grn1 putative GTPase FeoB_N PF02421.18 EWM30590.1 - 9.2e-07 28.5 0.3 2e-05 24.2 0.0 2.4 2 1 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EWM30590.1 - 1.8e-05 24.7 0.2 0.1 12.5 0.2 2.5 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EWM30590.1 - 0.00033 20.3 0.0 0.032 13.8 0.0 3.1 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EWM30590.1 - 0.0013 18.8 3.9 0.017 15.2 3.4 3.0 2 1 0 2 2 2 1 Dynamin family cobW PF02492.19 EWM30590.1 - 0.061 12.9 0.5 0.68 9.5 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AIG1 PF04548.16 EWM30590.1 - 0.11 11.8 0.7 0.22 10.8 0.0 1.8 2 0 0 2 2 2 0 AIG1 family AAA_16 PF13191.6 EWM30590.1 - 0.37 11.2 0.0 0.37 11.2 0.0 3.2 3 1 0 3 3 3 0 AAA ATPase domain NOA36 PF06524.12 EWM30590.1 - 0.7 9.2 6.7 1.8 7.8 6.7 1.7 1 0 0 1 1 1 0 NOA36 protein Exop_C PF18559.1 EWM30590.1 - 0.84 9.5 7.5 6.2 6.7 0.6 2.4 2 0 0 2 2 2 0 Galactose-binding domain-like PP2C PF00481.21 EWM30591.1 - 5.8e-48 163.8 0.1 6.4e-47 160.3 0.0 2.3 2 1 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 EWM30591.1 - 0.0025 17.5 0.7 0.014 15.1 0.7 2.3 1 1 0 1 1 1 1 Protein phosphatase 2C CAP_N PF01213.19 EWM30591.1 - 0.74 9.2 3.7 1.3 8.4 3.7 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Myb_DNA-binding PF00249.31 EWM30593.1 - 7.6e-23 80.4 2.5 4.5e-11 42.8 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EWM30593.1 - 2.9e-21 75.5 1.7 5.6e-14 52.1 0.4 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF4245 PF14030.6 EWM30594.1 - 1.2 9.1 4.5 15 5.6 0.8 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4245) Mpv17_PMP22 PF04117.12 EWM30595.1 - 1.2e-18 67.1 1.5 1.9e-18 66.4 1.5 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family GTP_EFTU PF00009.27 EWM30596.1 - 1e-28 100.2 0.0 1.6e-28 99.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EWM30596.1 - 9.5e-08 32.3 3.1 2.5e-05 24.6 0.1 3.4 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EWM30596.1 - 1.7e-06 28.1 0.0 3.1e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EWM30596.1 - 0.00054 19.4 0.1 0.0021 17.5 0.1 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RIBIOP_C PF04950.12 EWM30596.1 - 0.0014 18.1 0.7 0.56 9.6 0.0 2.3 2 0 0 2 2 2 2 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal ATP_bind_1 PF03029.17 EWM30596.1 - 0.032 14.0 0.0 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 EWM30596.1 - 0.037 13.9 0.0 0.36 10.7 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase cobW PF02492.19 EWM30596.1 - 0.049 13.2 0.2 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Beach PF02138.18 EWM30597.1 - 1e-107 359.6 0.0 1.3e-107 359.3 0.0 1.1 1 0 0 1 1 1 1 Beige/BEACH domain Branch PF02485.21 EWM30599.1 - 3.8e-17 62.6 0.0 5.4e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme GRP PF07172.11 EWM30603.1 - 2.5 8.8 8.7 2.5e+02 2.4 8.7 2.5 1 1 0 1 1 1 0 Glycine rich protein family Myb_DNA-binding PF00249.31 EWM30605.1 - 1.6e-23 82.6 15.3 1.6e-12 47.4 0.4 2.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EWM30605.1 - 3.3e-10 40.1 7.4 3e-05 24.2 1.7 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EWM30605.1 - 1.5e-05 24.8 2.5 0.0079 16.1 0.3 2.4 2 0 0 2 2 2 2 Myb DNA-binding like Neisseria_PilC PF05567.11 EWM30605.1 - 0.013 14.5 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 Neisseria PilC beta-propeller domain Annexin PF00191.20 EWM30605.1 - 0.23 11.5 0.7 0.44 10.6 0.1 1.7 2 0 0 2 2 2 0 Annexin PABP PF00658.18 EWM30606.1 - 3.6e-27 94.3 0.4 3.6e-27 94.3 0.4 1.9 2 1 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_1 PF00076.22 EWM30606.1 - 4e-08 33.0 0.1 8.4e-08 31.9 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.18 EWM30609.1 - 0.018 15.2 15.7 0.04 14.0 15.7 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0029 PF01205.19 EWM30610.1 - 5.8e-28 97.3 0.0 9.4e-28 96.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 DUF1949 PF09186.11 EWM30610.1 - 0.012 15.5 0.1 0.021 14.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1949) EFG_C PF00679.24 EWM30610.1 - 0.021 14.8 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 Elongation factor G C-terminus SAC3_GANP PF03399.16 EWM30611.1 - 6.2e-23 81.6 0.1 2.1e-21 76.6 0.1 2.2 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 EWM30611.1 - 0.014 15.3 0.0 0.033 14.2 0.0 1.5 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family SpoU_methylase PF00588.19 EWM30614.1 - 2.1e-18 66.8 0.0 5.9e-18 65.4 0.0 1.6 1 1 0 1 1 1 1 SpoU rRNA Methylase family Pkinase PF00069.25 EWM30615.1 - 8.5e-70 235.1 0.0 1e-69 234.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM30615.1 - 2.8e-36 125.1 0.0 3.7e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EWM30615.1 - 0.00011 21.6 0.0 0.0002 20.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EWM30615.1 - 0.00026 20.4 0.0 0.00061 19.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EWM30615.1 - 0.012 15.6 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RRM_1 PF00076.22 EWM30616.1 - 3.8e-48 161.2 0.0 1.7e-20 72.6 0.1 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EWM30616.1 - 1.4e-09 37.6 0.0 0.00017 21.2 0.0 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EWM30616.1 - 0.00093 19.3 0.0 5.2 7.3 0.0 3.7 3 2 0 3 3 3 1 RNA recognition motif DUF4523 PF15023.6 EWM30616.1 - 0.0073 16.2 0.0 1 9.1 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF4523) Nup35_RRM_2 PF14605.6 EWM30616.1 - 0.022 14.8 0.1 1.5 8.8 0.0 3.0 3 1 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Fibrillarin PF01269.17 EWM30617.1 - 2.7e-95 317.8 0.0 3.2e-95 317.5 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 EWM30617.1 - 1.2e-07 31.7 0.0 1.5e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltr_RsmB-F PF01189.17 EWM30617.1 - 0.0028 17.3 0.0 0.0062 16.2 0.0 1.5 1 1 1 2 2 2 1 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 EWM30617.1 - 0.015 15.1 0.1 0.031 14.0 0.1 1.7 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF1214 PF06742.11 EWM30618.1 - 9.4e-27 93.6 0.0 1.2e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1214) Pyridox_oxase_2 PF12766.7 EWM30619.1 - 4.4e-24 85.0 0.0 2.3e-23 82.7 0.0 2.0 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 EWM30619.1 - 0.0009 19.4 0.0 0.0024 18.0 0.0 1.7 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Thioredoxin PF00085.20 EWM30622.1 - 9.5e-25 86.6 0.0 1.4e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EWM30622.1 - 0.0033 17.9 0.0 0.12 12.9 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 EWM30622.1 - 0.0047 16.8 0.0 0.0078 16.1 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 EWM30622.1 - 0.005 17.0 0.0 0.0087 16.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 EWM30622.1 - 0.024 14.4 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_8 PF13905.6 EWM30622.1 - 0.027 14.8 0.0 0.61 10.5 0.0 2.3 1 1 1 2 2 2 0 Thioredoxin-like HTH_6 PF01418.17 EWM30622.1 - 0.076 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family SH2 PF00017.24 EWM30623.1 - 3.7e-09 36.6 0.0 7.4e-09 35.6 0.0 1.5 1 1 0 1 1 1 1 SH2 domain Cbl_N3 PF02762.14 EWM30623.1 - 0.051 13.4 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain SUR7 PF06687.12 EWM30627.1 - 0.0043 16.7 0.5 0.0069 16.0 0.5 1.3 1 0 0 1 1 1 1 SUR7/PalI family SUR7 PF06687.12 EWM30628.1 - 0.047 13.3 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 SUR7/PalI family DUF1772 PF08592.11 EWM30628.1 - 0.075 13.3 2.9 0.14 12.4 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Kinesin PF00225.23 EWM30629.1 - 1.6e-16 60.2 0.0 2.7e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Pkinase PF00069.25 EWM30631.1 - 1.9e-63 214.3 0.0 2.4e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EWM30631.1 - 9.3e-44 149.6 0.0 1.2e-43 149.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EWM30631.1 - 1.4e-06 27.3 0.0 2.6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EWM30631.1 - 1.1e-05 25.0 0.0 1.6e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EWM30631.1 - 0.0013 18.1 0.9 0.002 17.5 0.9 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family KIND PF16474.5 EWM30631.1 - 0.17 11.8 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain Ion_trans PF00520.31 EWM30632.1 - 2.9e-15 56.2 10.5 3.8e-15 55.8 10.5 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EWM30632.1 - 1.3e-06 27.4 7.4 2.7e-06 26.3 7.3 1.6 1 1 0 1 1 1 1 Polycystin cation channel DUF1664 PF07889.12 EWM30632.1 - 0.014 15.5 0.8 2.5 8.1 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CLZ PF16526.5 EWM30632.1 - 0.32 11.4 3.6 0.35 11.3 1.2 2.2 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels AOX PF01786.17 EWM30635.1 - 2.9e-89 298.3 0.6 3.6e-89 298.0 0.6 1.1 1 0 0 1 1 1 1 Alternative oxidase TYW3 PF02676.14 EWM30637.1 - 0.11 11.9 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase TYW3 DUF563 PF04577.14 EWM30639.1 - 8e-15 55.5 0.0 1e-14 55.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF563) TRM13 PF05206.14 EWM30639.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase TRM13 Ribonuclease_3 PF00636.26 EWM30643.1 - 0.12 13.0 0.0 0.45 11.2 0.0 1.9 1 1 0 1 1 1 0 Ribonuclease III domain SSP160 PF06933.11 EWM30645.1 - 3.1 5.9 8.2 4 5.5 8.2 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Glyco_hydro_38N PF01074.22 EWM30646.1 - 0.0095 15.3 0.0 0.012 14.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain SR-25 PF10500.9 EWM30646.1 - 2.9 7.5 13.7 4.1 7.0 13.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DER1 PF04511.15 EWM30647.1 - 6.5e-30 104.5 5.8 9.3e-30 104.0 5.8 1.2 1 0 0 1 1 1 1 Der1-like family RNA_pol_3_Rpc31 PF11705.8 EWM30647.1 - 0.00049 20.4 22.0 0.0007 19.9 22.0 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 PPP4R2 PF09184.11 EWM30647.1 - 0.0074 15.9 12.8 0.011 15.4 12.8 1.2 1 0 0 1 1 1 1 PPP4R2 Nop14 PF04147.12 EWM30647.1 - 0.0078 14.5 19.7 0.01 14.1 19.7 1.1 1 0 0 1 1 1 1 Nop14-like family Tim54 PF11711.8 EWM30647.1 - 0.017 13.9 5.1 0.023 13.5 5.1 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PBP_sp32 PF07222.12 EWM30647.1 - 0.02 14.4 7.9 0.029 13.8 7.9 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Ureide_permease PF07168.11 EWM30647.1 - 0.032 13.0 0.0 0.056 12.2 0.0 1.4 1 0 0 1 1 1 0 Ureide permease SAPS PF04499.15 EWM30647.1 - 0.036 12.8 1.8 0.044 12.6 1.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4820 PF16091.5 EWM30647.1 - 0.041 13.2 6.1 0.061 12.7 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) RR_TM4-6 PF06459.12 EWM30647.1 - 0.043 13.7 8.0 0.055 13.3 8.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 EWM30647.1 - 0.049 12.9 0.0 0.067 12.4 0.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF740 PF05340.12 EWM30647.1 - 0.15 10.8 8.5 0.19 10.5 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) RPN2_C PF18004.1 EWM30647.1 - 0.17 11.8 11.5 0.26 11.2 11.5 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain BUD22 PF09073.10 EWM30647.1 - 0.17 11.2 17.4 0.22 10.8 17.4 1.1 1 0 0 1 1 1 0 BUD22 TFIIA PF03153.13 EWM30647.1 - 0.17 11.8 14.6 0.23 11.4 14.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Merozoite_SPAM PF07133.11 EWM30647.1 - 0.19 11.7 41.7 0.28 11.2 41.7 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Spore_coat_CotO PF14153.6 EWM30647.1 - 0.23 11.4 12.4 0.34 10.8 12.4 1.2 1 0 0 1 1 1 0 Spore coat protein CotO RNA_pol_Rpc4 PF05132.14 EWM30647.1 - 0.49 10.8 4.6 0.82 10.1 4.6 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 TFB6 PF17110.5 EWM30647.1 - 0.95 9.2 7.4 1.6 8.5 7.4 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH TRAP_alpha PF03896.16 EWM30647.1 - 0.97 8.6 13.3 1.4 8.0 13.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Connexin PF00029.19 EWM30647.1 - 1.2 8.8 4.4 2.1 8.0 4.4 1.3 1 0 0 1 1 1 0 Connexin SDA1 PF05285.12 EWM30647.1 - 1.3 8.3 22.5 1.8 7.9 22.5 1.1 1 0 0 1 1 1 0 SDA1 Mpp10 PF04006.12 EWM30647.1 - 1.5 7.2 23.8 1.9 6.8 23.8 1.0 1 0 0 1 1 1 0 Mpp10 protein DUF913 PF06025.12 EWM30647.1 - 1.5 7.7 4.5 2.1 7.3 4.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DNA_pol_phi PF04931.13 EWM30647.1 - 1.9 6.5 32.7 2.8 5.9 32.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi PI3K_1B_p101 PF10486.9 EWM30647.1 - 2.4 5.9 8.5 3.3 5.4 8.5 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CPSF100_C PF13299.6 EWM30647.1 - 2.6 8.2 7.2 4 7.6 7.2 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Vfa1 PF08432.10 EWM30647.1 - 3.2 8.0 11.9 4.7 7.5 11.9 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 LAP1C PF05609.12 EWM30647.1 - 4.1 6.4 10.4 5.6 5.9 10.4 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CDC45 PF02724.14 EWM30647.1 - 4.4 5.5 18.6 6.2 5.0 18.6 1.1 1 0 0 1 1 1 0 CDC45-like protein CSRNP_N PF16019.5 EWM30647.1 - 5.8 6.8 7.4 12 5.8 7.3 1.4 2 0 0 2 2 1 0 Cysteine/serine-rich nuclear protein N-terminus FYDLN_acid PF09538.10 EWM30647.1 - 6 7.6 20.9 9.7 6.9 20.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) NOA36 PF06524.12 EWM30647.1 - 6.2 6.1 20.5 10 5.3 20.5 1.3 1 0 0 1 1 1 0 NOA36 protein Pox_Ag35 PF03286.14 EWM30647.1 - 6.7 6.5 16.9 10 5.9 16.9 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NPR3 PF03666.13 EWM30647.1 - 7.2 5.3 9.7 9.9 4.8 9.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RXT2_N PF08595.11 EWM30647.1 - 8.3 6.4 14.8 15 5.6 14.8 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal SMN PF06003.12 EWM30648.1 - 6.3e-06 25.6 0.0 7.8e-06 25.3 0.0 1.0 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) DUF4110 PF13422.6 EWM30649.1 - 6.4e-07 29.4 0.7 6.4e-07 29.4 0.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.6 EWM30650.1 - 8.1e-34 115.4 9.3 2.3e-08 33.9 0.0 7.3 4 2 2 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 EWM30650.1 - 2.2e-30 103.9 4.7 7.4e-12 45.1 0.0 6.2 4 1 2 6 6 6 4 Kelch motif Kelch_3 PF13415.6 EWM30650.1 - 4.2e-30 103.4 13.1 9.2e-10 38.6 0.0 7.4 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.6 EWM30650.1 - 1.5e-26 91.9 4.7 2.3e-05 24.2 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.25 EWM30650.1 - 8.3e-17 60.5 8.4 4.3e-06 26.2 0.2 6.4 6 1 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 EWM30650.1 - 3.3e-10 39.5 11.9 0.0085 16.0 0.7 6.4 7 1 0 7 7 7 2 Kelch motif UPF0560 PF10577.9 EWM30650.1 - 6.5 5.1 5.1 13 4.1 5.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 FHA PF00498.26 EWM30652.1 - 2.6e-10 40.5 0.0 5.6e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain FAM76 PF16046.5 EWM30652.1 - 0.34 10.2 15.1 0.073 12.4 11.6 1.6 2 0 0 2 2 2 0 FAM76 protein DUF5082 PF16888.5 EWM30652.1 - 0.97 9.7 15.4 3.8 7.8 1.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Spc7 PF08317.11 EWM30652.1 - 1.6 7.6 31.6 0.63 8.9 0.6 2.7 1 1 2 3 3 3 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 EWM30652.1 - 2 8.5 33.8 2.3 8.3 2.8 3.7 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CorA PF01544.18 EWM30652.1 - 2.7 7.2 8.9 5.5 6.2 8.3 1.8 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Fib_alpha PF08702.10 EWM30652.1 - 5.1 7.3 9.9 11 6.2 3.8 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FliD_N PF02465.18 EWM30652.1 - 6.6 7.5 8.0 2.4 8.9 2.1 2.8 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 N-terminus LPP PF04728.13 EWM30652.1 - 7.9 7.0 7.6 32 5.0 0.3 3.5 2 1 1 3 3 3 0 Lipoprotein leucine-zipper PCIF1_WW PF12237.8 EWM30653.1 - 7.9e-36 123.2 0.5 1.4e-35 122.4 0.5 1.3 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain MRP-63 PF14978.6 EWM30653.1 - 0.33 11.6 4.5 0.62 10.7 3.3 1.9 2 0 0 2 2 2 0 Mitochondrial ribosome protein 63 PCIF1_WW PF12237.8 EWM30654.1 - 2e-31 108.9 0.2 3.7e-31 108.1 0.2 1.3 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain MRP-63 PF14978.6 EWM30654.1 - 0.2 12.3 4.3 0.48 11.1 3.3 2.0 2 0 0 2 2 2 0 Mitochondrial ribosome protein 63 Aminotran_3 PF00202.21 EWM30657.1 - 9.3e-57 192.5 0.2 2.2e-51 174.8 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class-III PTPLA PF04387.14 EWM30658.1 - 3.8e-38 130.8 4.0 5.3e-38 130.3 4.0 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Indigoidine_A PF04227.12 EWM30659.1 - 2.4e-121 404.6 1.7 2.9e-121 404.3 1.7 1.1 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 EWM30659.1 - 1.7e-08 34.1 0.0 4.1e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Peptidase_M1 PF01433.20 EWM30660.1 - 9e-30 103.9 1.0 1.3e-29 103.3 1.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EWM30660.1 - 3.3e-10 40.5 0.0 5.8e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain HEAT_2 PF13646.6 EWM30660.1 - 3.3e-08 33.8 4.6 8.1e-06 26.1 0.6 3.1 2 1 0 2 2 2 2 HEAT repeats DUF2381 PF09544.10 EWM30660.1 - 0.0081 15.7 0.4 0.015 14.8 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2381) HEAT_EZ PF13513.6 EWM30660.1 - 0.025 15.1 0.6 0.25 11.9 0.0 2.6 2 0 0 2 2 2 0 HEAT-like repeat DUF3458 PF11940.8 EWM30660.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3458) Ig-like fold PspB PF06667.12 EWM30660.1 - 0.19 11.8 1.6 13 6.0 0.4 2.6 2 0 0 2 2 2 0 Phage shock protein B HEAT PF02985.22 EWM30660.1 - 0.61 10.5 2.2 9.7 6.8 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat Peptidase_M1 PF01433.20 EWM30661.1 - 9.4e-30 103.8 1.0 1.4e-29 103.3 1.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EWM30661.1 - 4.1e-10 40.2 0.0 7.2e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain HEAT_2 PF13646.6 EWM30661.1 - 3.4e-08 33.7 4.6 8.4e-06 26.1 0.6 3.1 2 1 0 2 2 2 2 HEAT repeats DUF2381 PF09544.10 EWM30661.1 - 0.0083 15.7 0.4 0.016 14.8 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2381) HEAT_EZ PF13513.6 EWM30661.1 - 0.027 15.0 0.6 0.26 11.8 0.0 2.6 2 0 0 2 2 2 0 HEAT-like repeat DUF3458 PF11940.8 EWM30661.1 - 0.11 12.9 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3458) Ig-like fold PspB PF06667.12 EWM30661.1 - 0.2 11.7 1.6 13 5.9 0.4 2.6 2 0 0 2 2 2 0 Phage shock protein B HEAT PF02985.22 EWM30661.1 - 0.66 10.4 2.2 10 6.7 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat Lipase_3 PF01764.25 EWM30663.1 - 1.5e-27 96.2 0.0 2.5e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) C2 PF00168.30 EWM30663.1 - 1.7e-10 41.1 0.0 3.7e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain Acetyltransf_1 PF00583.25 EWM30664.1 - 1.3e-08 35.1 0.0 4.3e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 EWM30664.1 - 2.6e-08 34.0 0.0 7.7e-08 32.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EWM30664.1 - 2.7e-06 27.3 0.0 7.5e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EWM30664.1 - 2.7e-05 24.5 0.0 6.2e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EWM30664.1 - 0.0067 17.1 0.0 0.017 15.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EWM30664.1 - 0.021 14.9 0.1 0.062 13.4 0.1 1.8 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 EWM30664.1 - 0.051 13.5 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein Zn_clus PF00172.18 EWM30665.1 - 1e-05 25.5 4.4 2.4e-05 24.4 4.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2484 PF10658.9 EWM30666.1 - 0.23 11.8 2.8 2.5 8.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2484) Claudin_3 PF06653.11 EWM30666.1 - 0.26 11.2 11.6 10 6.1 11.5 2.3 1 1 0 1 1 1 0 Tight junction protein, Claudin-like CDC45 PF02724.14 EWM30667.1 - 0.0064 14.8 0.5 0.0087 14.4 0.5 1.1 1 0 0 1 1 1 1 CDC45-like protein SpoIIIAH PF12685.7 EWM30667.1 - 0.54 10.0 15.2 0.39 10.5 0.2 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein Exo_endo_phos PF03372.23 EWM30668.1 - 1.8e-06 27.7 0.0 7.1e-06 25.7 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family 2OG-FeII_Oxy_3 PF13640.6 EWM30669.1 - 1.9e-14 54.3 0.0 1.8e-13 51.2 0.0 2.2 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 EWM30669.1 - 0.0013 19.4 0.0 1.3 9.8 0.0 2.4 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 EWM30669.1 - 0.14 12.5 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Aminotran_3 PF00202.21 EWM30671.1 - 8.8e-06 24.6 0.0 1.2e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III BTB PF00651.31 EWM30672.1 - 1.8e-18 66.8 0.2 3.4e-15 56.2 0.0 3.2 2 1 1 3 3 3 2 BTB/POZ domain Kelch_5 PF13854.6 EWM30672.1 - 1.6e-10 40.7 0.0 0.0061 16.5 0.0 4.8 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 EWM30672.1 - 4.6e-05 23.2 0.4 5.9 7.0 0.0 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 EWM30672.1 - 0.0029 17.9 4.0 5.9 7.3 0.1 5.4 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_4 PF13418.6 EWM30672.1 - 0.0043 17.0 2.7 3.5 7.7 0.0 5.2 6 0 0 6 6 6 1 Galactose oxidase, central domain WD40 PF00400.32 EWM30672.1 - 0.072 14.0 3.8 0.91 10.5 0.2 3.7 3 0 0 3 3 3 0 WD domain, G-beta repeat STI1 PF17830.1 EWM30673.1 - 0.00026 20.8 2.0 0.022 14.7 0.3 3.2 2 0 0 2 2 2 1 STI1 domain MobL PF18555.1 EWM30673.1 - 0.042 13.1 0.9 0.055 12.7 0.9 1.2 1 0 0 1 1 1 0 MobL relaxases Tht1 PF04163.12 EWM30673.1 - 0.26 10.0 0.7 0.32 9.7 0.7 1.1 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein YkyA PF10368.9 EWM30673.1 - 2.7 7.6 9.0 2.7 7.6 2.9 2.5 2 1 1 3 3 3 0 Putative cell-wall binding lipoprotein GerD PF17898.1 EWM30673.1 - 4.5 7.3 8.3 2.6 8.0 0.1 3.3 3 1 0 3 3 3 0 Spore germination GerD central core domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Eustygmatophyta/Nannochloropsis_gaditana-NagaB31_1.0/GCA_000569095.1_NagaB31_1.0_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Eustygmatophyta/Nannochloropsis_gaditana-NagaB31_1.0/GCA_000569095.1_NagaB31_1.0_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Eustygmatophyta/Nannochloropsis_gaditana-NagaB31_1.0/GCA_000569095.1_NagaB31_1.0_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Eustygmatophyta/Nannochloropsis_gaditana-NagaB31_1.0/GCA_000569095.1_NagaB31_1.0_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 10:41:19 2019 # [ok]