# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- RNA_pol_Rpb1_5 PF04998.12 AFZ64212.1 - 1.5e-56 191.6 2.7 1.8e-54 184.8 1.9 2.6 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_4 PF05000.12 AFZ64212.1 - 4.9e-12 45.5 0.2 4e-11 42.6 0.0 2.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_3 PF04983.13 AFZ64212.1 - 4.5e-05 23.2 0.2 0.0003 20.5 0.0 2.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 Arg_repressor PF01316.16 AFZ64212.1 - 0.0027 17.2 0.0 0.085 12.4 0.0 2.7 2 0 0 2 2 2 1 Arginine repressor, DNA binding domain RNA_pol_Rpb2_6 PF00562.23 AFZ64213.1 - 1.2e-136 455.4 0.0 2.2e-136 454.6 0.0 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 AFZ64213.1 - 1.1e-27 96.2 0.1 2e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 AFZ64213.1 - 5e-27 93.9 0.0 1e-26 93.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.11 AFZ64213.1 - 2.7e-25 87.9 0.0 6.8e-25 86.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.9 AFZ64213.1 - 4e-25 88.3 1.9 1.3e-23 83.4 1.3 2.2 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_45 PF10385.4 AFZ64213.1 - 4e-06 26.5 0.0 9.6e-06 25.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase beta subunit external 1 domain SecA_DEAD PF07517.9 AFZ64214.1 - 3e-97 325.0 0.2 4.6e-97 324.4 0.1 1.2 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_PP_bind PF01043.15 AFZ64214.1 - 2.1e-30 105.4 0.0 8.1e-30 103.5 0.0 2.1 1 0 0 1 1 1 1 SecA preprotein cross-linking domain SecA_SW PF07516.8 AFZ64214.1 - 1.4e-16 60.9 4.5 8.5e-15 55.1 1.5 3.2 2 1 0 2 2 2 1 SecA Wing and Scaffold domain DEAD PF00270.24 AFZ64214.1 - 7e-07 28.8 0.1 1.7e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase RNA_pol_Rpb1_1 PF04997.7 AFZ64215.1 - 2.8e-59 201.0 4.9 5.5e-59 200.1 0.5 2.5 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 AFZ64215.1 - 2.1e-42 144.8 0.1 3e-40 137.9 0.0 3.4 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 AFZ64215.1 - 2.7e-11 43.4 0.2 2.4e-10 40.3 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 DUF1882 PF08966.6 AFZ64215.1 - 0.14 12.1 2.4 1.8 8.5 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF1882) Auto_anti-p27 PF06677.7 AFZ64215.1 - 0.63 9.8 3.5 1.3 8.8 2.4 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) PsaA_PsaB PF00223.14 AFZ64216.1 - 0 1155.4 36.0 0 1155.2 25.0 1.0 1 0 0 1 1 1 1 Photosystem I psaA/psaB protein PsaA_PsaB PF00223.14 AFZ64217.1 - 0 1078.6 35.7 0 1078.4 24.7 1.0 1 0 0 1 1 1 1 Photosystem I psaA/psaB protein Peptidase_M41 PF01434.13 AFZ64218.1 - 1.2e-58 198.0 0.1 1.2e-58 198.0 0.1 1.6 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.24 AFZ64218.1 - 2e-45 154.1 0.3 7.5e-45 152.3 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 AFZ64218.1 - 7.7e-07 28.9 0.3 4e-05 23.3 0.0 3.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) FtsH_ext PF06480.10 AFZ64218.1 - 1.3e-05 25.3 1.6 4.3e-05 23.6 0.1 2.6 3 0 0 3 3 2 1 FtsH Extracellular AAA_22 PF13401.1 AFZ64218.1 - 2.9e-05 24.1 0.3 0.0013 18.9 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AFZ64218.1 - 5.4e-05 23.2 0.9 0.0034 17.3 0.1 3.2 2 2 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 AFZ64218.1 - 8.6e-05 21.6 0.0 0.0005 19.1 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 AFZ64218.1 - 0.00014 21.5 0.4 0.00047 19.8 0.2 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 AFZ64218.1 - 0.00016 22.4 0.1 0.00063 20.5 0.0 2.2 2 1 0 2 2 1 1 AAA domain AAA_2 PF07724.9 AFZ64218.1 - 0.00019 21.3 0.1 0.00086 19.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 AFZ64218.1 - 0.0002 20.8 0.1 0.083 12.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 AFZ64218.1 - 0.00022 20.1 0.1 0.00022 20.1 0.1 1.8 2 0 0 2 2 2 1 TIP49 C-terminus AAA_14 PF13173.1 AFZ64218.1 - 0.00027 20.8 0.0 0.0011 18.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 AFZ64218.1 - 0.00087 18.4 0.3 0.014 14.5 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin IstB_IS21 PF01695.12 AFZ64218.1 - 0.0014 18.0 0.0 0.003 17.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 AFZ64218.1 - 0.0082 15.3 0.0 0.02 14.0 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 AFZ64218.1 - 0.014 15.6 0.8 0.098 12.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 AFZ64218.1 - 0.026 14.1 0.0 0.23 11.1 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 AFZ64218.1 - 0.03 14.2 0.0 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 AFZ64218.1 - 0.036 13.9 0.0 0.095 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 AFZ64218.1 - 0.041 13.3 0.0 0.13 11.6 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.1 AFZ64218.1 - 0.15 11.6 1.3 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 AFZ64218.1 - 8.4 6.6 9.9 26 5.0 0.1 2.7 2 0 0 2 2 2 0 AAA domain HSP70 PF00012.15 AFZ64219.1 - 1e-237 789.8 13.7 1.2e-237 789.7 9.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 AFZ64219.1 - 2.3e-23 82.2 2.8 1.5e-19 69.7 0.0 3.4 3 1 0 3 3 3 2 MreB/Mbl protein StbA PF06406.6 AFZ64219.1 - 0.0013 17.7 0.1 0.0013 17.7 0.0 2.4 3 0 0 3 3 3 1 StbA protein FtsA PF14450.1 AFZ64219.1 - 0.0015 18.3 6.0 0.73 9.6 0.1 4.0 2 2 0 2 2 2 2 Cell division protein FtsA Hydantoinase_A PF01968.13 AFZ64219.1 - 0.049 12.7 1.4 0.19 10.7 0.1 2.6 2 1 0 2 2 2 0 Hydantoinase/oxoprolinase FGGY_C PF02782.11 AFZ64219.1 - 0.054 13.1 0.0 0.29 10.7 0.0 2.1 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain PSII PF00421.14 AFZ64220.1 - 2.1e-198 659.3 6.4 2.4e-198 659.1 4.5 1.0 1 0 0 1 1 1 1 Photosystem II protein Oxidored_nitro PF00148.14 AFZ64221.1 - 8.5e-91 304.5 0.0 9.9e-91 304.3 0.0 1.0 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase PCP_red PF08369.5 AFZ64221.1 - 4.5e-15 55.2 0.0 9.8e-15 54.1 0.0 1.6 1 0 0 1 1 1 1 Proto-chlorophyllide reductase 57 kD subunit ATP-synt_ab PF00006.20 AFZ64222.1 - 3.9e-71 238.9 0.3 5.6e-71 238.4 0.2 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 AFZ64222.1 - 7e-23 81.2 2.0 1.6e-22 80.1 0.8 2.1 1 1 1 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 AFZ64222.1 - 2.6e-09 37.1 5.7 6.2e-09 35.9 3.9 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain KaiC PF06745.8 AFZ64222.1 - 6.1e-06 25.5 0.1 1.4e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 KaiC HAS-barrel PF09378.5 AFZ64222.1 - 0.0047 16.8 5.2 0.011 15.6 3.6 1.7 1 0 0 1 1 1 1 HAS barrel domain AAA_25 PF13481.1 AFZ64222.1 - 0.092 12.1 0.0 0.47 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 AFZ64223.1 - 1.6e-27 96.3 0.1 5.8e-27 94.4 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AFZ64223.1 - 0.00023 21.2 0.7 0.7 10.0 0.1 3.5 3 1 0 4 4 4 2 AAA domain AAA_17 PF13207.1 AFZ64223.1 - 0.00035 21.3 0.0 0.0017 19.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 AFZ64223.1 - 0.0013 18.4 1.5 0.19 11.3 0.1 2.5 1 1 1 2 2 2 2 NACHT domain DUF815 PF05673.8 AFZ64223.1 - 0.0035 16.2 0.1 0.027 13.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 AFZ64223.1 - 0.0051 16.7 0.0 0.0091 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 AFZ64223.1 - 0.019 14.9 0.4 0.76 9.7 0.0 2.6 2 1 1 3 3 3 0 AAA ATPase domain AAA_5 PF07728.9 AFZ64223.1 - 0.026 14.2 0.4 0.43 10.2 0.3 2.9 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 AFZ64223.1 - 0.12 11.4 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin KaiC PF06745.8 AFZ64223.1 - 0.19 10.8 1.3 0.49 9.4 0.0 2.3 3 0 0 3 3 3 0 KaiC UPF0051 PF01458.12 AFZ64224.1 - 1.7e-62 210.9 0.5 2.1e-62 210.5 0.4 1.1 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) DUF1250 PF06855.7 AFZ64224.1 - 0.098 12.1 0.1 0.25 10.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1250) TPP_enzyme_C PF02775.16 AFZ64225.1 - 4.3e-49 165.9 0.0 2.3e-48 163.6 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 AFZ64225.1 - 2.3e-47 160.1 0.0 4.1e-47 159.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.13 AFZ64225.1 - 6.6e-19 68.0 0.0 1.7e-18 66.6 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain ATP-synt_ab PF00006.20 AFZ64226.1 - 1.6e-62 210.8 0.1 3e-62 209.9 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 AFZ64226.1 - 1.1e-26 93.5 0.3 2.1e-26 92.6 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 AFZ64226.1 - 3.7e-13 49.4 0.2 8.7e-13 48.2 0.1 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain KaiC PF06745.8 AFZ64226.1 - 0.00036 19.7 0.2 0.00078 18.6 0.0 1.6 2 0 0 2 2 2 1 KaiC DUF258 PF03193.11 AFZ64226.1 - 0.0039 16.4 0.0 0.009 15.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 AFZ64226.1 - 0.007 16.0 0.0 0.019 14.6 0.0 1.7 2 0 0 2 2 2 1 Archaeal ATPase NB-ARC PF00931.17 AFZ64226.1 - 0.011 14.5 0.1 0.024 13.4 0.1 1.5 1 0 0 1 1 1 0 NB-ARC domain MobB PF03205.9 AFZ64226.1 - 0.013 15.2 0.1 0.8 9.4 0.0 2.8 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 AFZ64226.1 - 0.014 15.5 0.1 1.4 9.1 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 AFZ64226.1 - 0.022 15.0 0.0 0.17 12.1 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_25 PF13481.1 AFZ64226.1 - 0.052 12.9 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 AFZ64226.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 AFZ64226.1 - 0.15 12.2 0.0 0.42 10.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase RuBisCO_large PF00016.15 AFZ64227.1 - 4e-158 525.1 0.1 4.9e-158 524.8 0.1 1.1 1 0 0 1 1 1 1 Ribulose bisphosphate carboxylase large chain, catalytic domain RuBisCO_large_N PF02788.11 AFZ64227.1 - 1.2e-64 215.6 0.3 2.4e-64 214.6 0.2 1.5 1 0 0 1 1 1 1 Ribulose bisphosphate carboxylase large chain, N-terminal domain PSII PF00421.14 AFZ64228.1 - 1.2e-204 679.8 10.2 1.4e-204 679.6 7.1 1.0 1 0 0 1 1 1 1 Photosystem II protein Cpn60_TCP1 PF00118.19 AFZ64229.1 - 2.9e-49 168.0 5.6 3.3e-49 167.8 3.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AAA_2 PF07724.9 AFZ64230.1 - 5.8e-53 179.3 0.0 1e-52 178.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 AFZ64230.1 - 1.1e-16 60.4 0.0 3e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 AFZ64230.1 - 1.4e-13 50.7 0.0 3.3e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 AFZ64230.1 - 1.9e-09 37.8 0.0 2.3e-08 34.2 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AFZ64230.1 - 2.9e-06 27.4 0.3 0.00029 20.9 0.0 3.3 1 1 1 2 2 2 1 AAA domain Torsin PF06309.6 AFZ64230.1 - 1.2e-05 25.2 0.0 2.6e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Torsin Sigma54_activat PF00158.21 AFZ64230.1 - 1.7e-05 24.3 0.0 3.1e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Zeta_toxin PF06414.7 AFZ64230.1 - 3.4e-05 23.0 0.0 0.00011 21.3 0.0 1.8 1 1 1 2 2 2 1 Zeta toxin AAA_14 PF13173.1 AFZ64230.1 - 4.4e-05 23.3 0.0 0.00015 21.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.1 AFZ64230.1 - 6.3e-05 23.7 0.0 0.00041 21.1 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 AFZ64230.1 - 0.0002 21.3 0.2 0.0009 19.2 0.0 2.1 2 1 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.1 AFZ64230.1 - 0.00029 21.1 0.0 0.00065 20.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 AFZ64230.1 - 0.0041 17.2 1.5 0.034 14.3 0.0 2.8 3 0 0 3 3 2 1 RNA helicase AAA_33 PF13671.1 AFZ64230.1 - 0.0044 16.8 0.1 0.12 12.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 AFZ64230.1 - 0.011 14.6 0.1 0.022 13.6 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein IstB_IS21 PF01695.12 AFZ64230.1 - 0.033 13.6 0.0 0.092 12.1 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein DNA_pol3_delta2 PF13177.1 AFZ64230.1 - 0.036 13.7 0.0 0.69 9.5 0.0 2.4 1 1 0 1 1 1 0 DNA polymerase III, delta subunit DEAD PF00270.24 AFZ64230.1 - 0.041 13.3 0.1 0.42 10.0 0.1 2.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase RuvB_N PF05496.7 AFZ64230.1 - 0.042 12.8 0.0 0.12 11.4 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus UPF0079 PF02367.12 AFZ64230.1 - 0.047 13.3 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_3 PF07726.6 AFZ64230.1 - 0.065 12.8 0.0 4.6 6.8 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 AFZ64230.1 - 0.069 12.8 0.1 0.38 10.4 0.0 2.1 3 0 0 3 3 3 0 Archaeal ATPase AAA_10 PF12846.2 AFZ64230.1 - 0.074 12.4 0.0 0.14 11.5 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain RNA_pol_L PF01193.19 AFZ64231.1 - 9.8e-09 34.2 0.1 1.9e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_A_bac PF01000.21 AFZ64231.1 - 3e-05 24.1 0.1 0.00011 22.3 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain Oxidored_nitro PF00148.14 AFZ64232.1 - 2.1e-40 138.6 0.0 2.4e-40 138.4 0.0 1.0 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase ResB PF05140.9 AFZ64233.1 - 5.6e-59 199.9 2.4 2.4e-56 191.2 1.6 2.0 1 1 0 1 1 1 1 ResB-like family Mg_chelatase PF01078.16 AFZ64234.1 - 4.7e-10 38.9 0.0 1.9e-06 27.2 0.0 2.5 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 AFZ64234.1 - 7.7e-08 32.1 0.0 0.00047 19.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) MCM PF00493.18 AFZ64234.1 - 1.1e-06 27.6 0.0 0.0093 14.8 0.0 2.9 2 1 0 2 2 2 2 MCM2/3/5 family AAA_22 PF13401.1 AFZ64234.1 - 4.2e-06 26.9 0.1 9.8e-05 22.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 AFZ64234.1 - 1.6e-05 25.0 0.1 0.00014 21.8 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 AFZ64234.1 - 0.00018 20.9 0.0 0.00035 20.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Sigma54_activat PF00158.21 AFZ64234.1 - 0.00093 18.7 0.0 0.22 10.9 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA PF00004.24 AFZ64234.1 - 0.0065 16.6 0.0 0.098 12.8 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 AFZ64234.1 - 0.0071 15.3 0.0 0.025 13.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_18 PF13238.1 AFZ64234.1 - 0.011 16.0 0.1 0.45 10.8 0.0 2.7 3 0 0 3 3 2 0 AAA domain Miro PF08477.8 AFZ64234.1 - 0.016 15.6 0.0 0.045 14.2 0.0 1.8 2 0 0 2 2 1 0 Miro-like protein T2SE PF00437.15 AFZ64234.1 - 0.017 14.0 0.0 0.034 13.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_17 PF13207.1 AFZ64234.1 - 0.022 15.5 0.2 0.1 13.4 0.1 2.3 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 AFZ64234.1 - 0.027 14.7 0.0 0.15 12.3 0.0 2.0 2 0 0 2 2 2 0 ABC transporter MobB PF03205.9 AFZ64234.1 - 0.055 13.1 0.1 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 AFZ64234.1 - 0.084 12.7 0.0 0.43 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 AFZ64234.1 - 0.085 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_23 PF13476.1 AFZ64234.1 - 0.24 11.6 2.2 0.37 11.0 0.2 2.1 1 1 1 2 2 2 0 AAA domain GTP_EFTU PF00009.22 AFZ64235.1 - 2.4e-61 206.4 0.2 3.3e-61 206.0 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 AFZ64235.1 - 5.9e-34 116.1 1.4 1.6e-33 114.8 0.0 2.3 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 AFZ64235.1 - 9.4e-20 70.5 5.9 2.5e-19 69.1 4.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 AFZ64235.1 - 3.7e-06 26.8 0.2 1.2e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 AFZ64235.1 - 0.00014 21.3 2.3 0.00014 21.3 1.6 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Miro PF08477.8 AFZ64235.1 - 0.036 14.5 0.0 0.072 13.5 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein cobW PF02492.14 AFZ64235.1 - 0.072 12.5 0.8 0.13 11.6 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SecY PF00344.15 AFZ64236.1 - 9.3e-33 113.5 14.0 1.3e-32 113.0 9.7 1.2 1 0 0 1 1 1 1 SecY translocase DUF3681 PF12442.3 AFZ64236.1 - 0.12 12.5 1.2 3.9 7.6 1.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3681) AAA PF00004.24 AFZ64237.1 - 2.9e-15 56.6 0.0 6.9e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 AFZ64237.1 - 7.3e-08 32.6 0.2 6.3e-07 29.5 0.1 2.4 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 AFZ64237.1 - 1.2e-07 31.9 0.0 5.5e-05 23.3 0.0 3.2 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 AFZ64237.1 - 2.8e-05 23.8 0.0 0.00037 20.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 AFZ64237.1 - 9.7e-05 22.1 0.6 0.00059 19.6 0.0 2.5 3 1 1 4 4 4 1 Archaeal ATPase TniB PF05621.6 AFZ64237.1 - 0.00022 20.1 0.0 0.00039 19.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein NACHT PF05729.7 AFZ64237.1 - 0.00025 20.7 0.0 0.00057 19.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.1 AFZ64237.1 - 0.00083 19.2 0.1 0.0037 17.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 AFZ64237.1 - 0.0014 18.1 0.0 0.0027 17.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_10 PF12846.2 AFZ64237.1 - 0.0028 17.1 0.1 4.9 6.5 0.0 3.2 2 1 1 3 3 3 1 AAA-like domain Miro PF08477.8 AFZ64237.1 - 0.0056 17.1 0.0 0.056 13.9 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein AAA_25 PF13481.1 AFZ64237.1 - 0.0092 15.3 0.0 0.031 13.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AFZ64237.1 - 0.01 16.6 0.2 0.096 13.5 0.0 2.6 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 AFZ64237.1 - 0.011 15.4 0.1 0.16 11.6 0.0 2.4 2 0 0 2 2 2 0 NTPase Sigma54_activat PF00158.21 AFZ64237.1 - 0.023 14.1 0.0 0.065 12.7 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain DnaB_C PF03796.10 AFZ64237.1 - 0.029 13.2 0.0 0.054 12.3 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain RNA_helicase PF00910.17 AFZ64237.1 - 0.03 14.4 0.0 0.19 11.9 0.0 2.1 2 0 0 2 2 2 0 RNA helicase RuvB_N PF05496.7 AFZ64237.1 - 0.047 12.7 0.1 5.7 5.9 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 AFZ64237.1 - 0.051 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain DUF2075 PF09848.4 AFZ64237.1 - 0.068 12.1 0.0 0.18 10.7 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TIP49 PF06068.8 AFZ64237.1 - 0.075 11.7 0.0 0.42 9.2 0.0 1.9 2 0 0 2 2 2 0 TIP49 C-terminus DUF258 PF03193.11 AFZ64237.1 - 0.14 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Photo_RC PF00124.14 AFZ64238.1 - 2.5e-92 308.5 15.6 2.9e-92 308.3 10.8 1.0 1 0 0 1 1 1 1 Photosynthetic reaction centre protein Photo_RC PF00124.14 AFZ64239.1 - 3.7e-79 265.3 18.8 4.5e-79 265.1 13.0 1.0 1 0 0 1 1 1 1 Photosynthetic reaction centre protein Rubrerythrin PF02915.12 AFZ64240.1 - 1.5e-39 135.4 0.1 3.2e-39 134.3 0.0 1.6 1 0 0 1 1 1 1 Rubrerythrin rve_3 PF13683.1 AFZ64240.1 - 0.0033 16.9 0.2 0.0084 15.6 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain AAA PF00004.24 AFZ64241.1 - 6.2e-13 49.0 0.0 1.4e-12 47.9 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 AFZ64241.1 - 1.4e-06 28.4 0.0 0.053 13.6 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_17 PF13207.1 AFZ64241.1 - 2.2e-05 25.2 0.1 7.7e-05 23.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 AFZ64241.1 - 0.00051 19.9 0.0 0.00086 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 AFZ64241.1 - 0.00068 18.8 0.2 0.005 16.0 0.1 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 AFZ64241.1 - 0.00084 19.0 0.0 0.0016 18.1 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 AFZ64241.1 - 0.0012 19.1 0.1 0.0036 17.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 AFZ64241.1 - 0.0018 17.5 0.0 0.0033 16.6 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 NTPase_1 PF03266.10 AFZ64241.1 - 0.0038 16.9 0.0 0.0081 15.8 0.0 1.5 1 0 0 1 1 1 1 NTPase AAA_5 PF07728.9 AFZ64241.1 - 0.0038 16.9 0.0 0.0091 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 AFZ64241.1 - 0.0042 16.1 0.0 0.068 12.1 0.0 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ArgK PF03308.11 AFZ64241.1 - 0.007 15.1 0.2 0.02 13.6 0.1 1.7 1 1 1 2 2 2 1 ArgK protein RNA_helicase PF00910.17 AFZ64241.1 - 0.011 15.8 0.1 0.071 13.2 0.0 2.3 2 1 1 3 3 3 0 RNA helicase Torsin PF06309.6 AFZ64241.1 - 0.015 15.1 0.0 0.037 13.9 0.0 1.7 1 0 0 1 1 1 0 Torsin Zot PF05707.7 AFZ64241.1 - 0.018 14.5 0.1 0.38 10.2 0.1 2.3 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_28 PF13521.1 AFZ64241.1 - 0.028 14.3 0.0 0.049 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.4 AFZ64241.1 - 0.033 12.8 0.0 0.05 12.2 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.7 AFZ64241.1 - 0.035 13.1 0.0 0.065 12.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ResIII PF04851.10 AFZ64241.1 - 0.041 13.7 0.0 0.14 11.9 0.0 1.8 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_2 PF07724.9 AFZ64241.1 - 0.047 13.6 0.1 0.11 12.4 0.0 1.6 2 0 0 2 2 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 AFZ64241.1 - 0.064 12.6 0.1 0.14 11.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 AFZ64241.1 - 0.074 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.1 AFZ64241.1 - 0.091 12.3 0.1 0.19 11.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.15 AFZ64241.1 - 0.098 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Sigma54_activ_2 PF14532.1 AFZ64241.1 - 0.1 12.6 0.0 0.34 10.9 0.0 1.9 1 1 1 2 2 2 0 Sigma-54 interaction domain Apocytochr_F_C PF01333.14 AFZ64242.1 - 4.7e-47 158.6 2.8 7.6e-47 158.0 1.9 1.3 1 0 0 1 1 1 1 Apocytochrome F, C-terminal Cytochrom_C_asm PF01578.15 AFZ64243.1 - 3e-64 216.4 19.7 3e-64 216.4 13.7 2.2 2 1 0 2 2 2 1 Cytochrome C assembly protein Fer4_NifH PF00142.13 AFZ64244.1 - 3.9e-100 334.5 0.0 4.4e-100 334.3 0.0 1.0 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CbiA PF01656.18 AFZ64244.1 - 2e-18 66.4 0.0 2.9e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 AFZ64244.1 - 9e-09 34.7 0.4 9e-09 34.7 0.3 1.6 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.1 AFZ64244.1 - 3.7e-08 33.4 0.1 7.1e-07 29.2 0.1 2.3 1 1 0 1 1 1 1 AAA domain MipZ PF09140.6 AFZ64244.1 - 6.5e-05 22.1 0.1 0.00013 21.1 0.1 1.4 1 0 0 1 1 1 1 ATPase MipZ ArgK PF03308.11 AFZ64244.1 - 0.015 14.0 0.5 0.026 13.3 0.0 1.6 2 0 0 2 2 2 0 ArgK protein AAA_16 PF13191.1 AFZ64244.1 - 0.021 14.8 0.0 0.092 12.7 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.1 AFZ64244.1 - 0.021 14.2 0.0 0.048 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 AFZ64244.1 - 0.022 14.2 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_26 PF13500.1 AFZ64244.1 - 0.083 12.4 0.0 0.31 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 AFZ64244.1 - 0.22 11.3 1.7 1.4 8.7 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 ABC_tran PF00005.22 AFZ64245.1 - 1.5e-16 60.8 0.0 2.6e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 AFZ64245.1 - 1.7e-06 28.2 11.0 0.00039 20.4 5.2 3.0 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 AFZ64245.1 - 6.7e-05 23.6 0.1 0.00033 21.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 AFZ64245.1 - 0.0001 21.6 1.2 0.21 10.7 0.2 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_13 PF13166.1 AFZ64245.1 - 0.00051 18.6 0.0 0.00081 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 AFZ64245.1 - 0.0006 19.9 0.2 0.25 11.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 AFZ64245.1 - 0.0074 15.4 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 AFZ64245.1 - 0.0087 16.3 1.4 0.045 14.0 0.2 2.5 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 AFZ64245.1 - 0.012 15.9 2.7 0.018 15.3 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 AFZ64245.1 - 0.013 14.9 1.9 0.014 14.9 0.3 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_33 PF13671.1 AFZ64245.1 - 0.018 14.9 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 AFZ64245.1 - 0.041 13.2 0.0 0.076 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 AFZ64245.1 - 0.051 13.7 0.1 1.1 9.4 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MutS_V PF00488.16 AFZ64245.1 - 0.055 12.8 0.1 0.39 10.0 0.0 2.2 2 0 0 2 2 2 0 MutS domain V AAA_5 PF07728.9 AFZ64245.1 - 0.092 12.4 0.0 4.4 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 AFZ64245.1 - 0.1 12.5 0.0 0.29 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 AFZ64245.1 - 0.1 12.4 0.5 1 9.2 0.0 2.5 2 1 0 2 2 2 0 AAA domain Ribosomal_L2_C PF03947.13 AFZ64246.1 - 1.2e-58 196.4 0.2 1.9e-58 195.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 AFZ64246.1 - 1.7e-35 120.8 4.5 1.3e-34 117.9 3.2 2.1 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain ThiG PF05690.9 AFZ64247.1 - 3.2e-97 324.4 0.1 3.6e-97 324.2 0.1 1.0 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 AFZ64247.1 - 1.3e-08 34.4 0.2 6.7e-08 32.0 0.0 1.9 2 0 0 2 2 2 1 Histidine biosynthesis protein Dus PF01207.12 AFZ64247.1 - 5.6e-06 25.4 0.1 8.8e-06 24.7 0.1 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) FMN_dh PF01070.13 AFZ64247.1 - 7.3e-05 21.7 0.1 0.00012 21.0 0.0 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 AFZ64247.1 - 0.00034 19.6 0.3 0.00047 19.1 0.2 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NanE PF04131.9 AFZ64247.1 - 0.00087 18.2 0.2 0.0029 16.6 0.1 1.9 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase PcrB PF01884.12 AFZ64247.1 - 0.0075 15.5 0.2 0.012 14.8 0.1 1.3 1 0 0 1 1 1 1 PcrB family IGPS PF00218.16 AFZ64247.1 - 0.051 12.6 0.1 0.076 12.0 0.0 1.2 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase Ribosomal_L4 PF00573.17 AFZ64248.1 - 2.3e-38 131.5 0.1 3e-38 131.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family TatC PF00902.13 AFZ64249.1 - 5.5e-39 133.7 23.5 5.5e-39 133.7 16.3 1.2 1 1 0 1 1 1 1 Sec-independent protein translocase protein (TatC) Ribosomal_S2 PF00318.15 AFZ64250.1 - 3.4e-72 242.0 0.1 3.9e-72 241.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S2 UPF0193 PF05250.6 AFZ64250.1 - 0.012 15.1 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0193) ATP-synt_A PF00119.15 AFZ64251.1 - 1.1e-52 178.7 10.1 1.2e-52 178.5 7.0 1.0 1 0 0 1 1 1 1 ATP synthase A chain Glyco_trans_2_3 PF13632.1 AFZ64251.1 - 0.18 11.4 3.3 0.44 10.2 1.3 2.2 1 1 0 1 1 1 0 Glycosyl transferase family group 2 Ribosomal_L1 PF00687.16 AFZ64252.1 - 3e-45 154.2 0.2 3.5e-45 154.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Cytochrom_B_N_2 PF13631.1 AFZ64253.1 - 7.2e-40 136.5 7.1 7.2e-40 136.5 4.9 1.5 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_N PF00033.14 AFZ64253.1 - 2.2e-17 63.0 12.6 3e-17 62.6 8.7 1.1 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Ni_hydr_CYTB PF01292.15 AFZ64253.1 - 6.6e-06 25.6 4.3 6.6e-06 25.6 3.0 2.1 1 1 1 2 2 2 2 Prokaryotic cytochrome b561 DUF4405 PF14358.1 AFZ64253.1 - 1.3 9.1 17.2 0.044 13.9 4.4 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4405) Na_Ca_ex PF01699.19 AFZ64253.1 - 1.4 8.4 8.3 0.43 10.1 2.7 2.1 2 1 0 2 2 2 0 Sodium/calcium exchanger protein S4 PF01479.20 AFZ64254.1 - 8.5e-20 69.9 0.0 2.3e-19 68.5 0.0 1.8 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.14 AFZ64254.1 - 1e-19 70.6 10.1 1e-19 70.6 7.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain S4_2 PF13275.1 AFZ64254.1 - 0.0082 15.7 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 S4 domain Ribosomal_L3 PF00297.17 AFZ64255.1 - 4.7e-38 131.0 0.6 4.1e-36 124.7 0.4 2.1 1 1 0 1 1 1 1 Ribosomal protein L3 YGGT PF02325.12 AFZ64257.1 - 4.2e-06 26.6 0.4 1e-05 25.3 0.3 1.7 1 0 0 1 1 1 1 YGGT family Ycf4 PF02392.11 AFZ64258.1 - 6.9e-24 84.1 0.4 8.6e-24 83.8 0.2 1.0 1 0 0 1 1 1 1 Ycf4 PSI_PsaF PF02507.10 AFZ64259.1 - 7.2e-79 263.3 0.0 8.6e-79 263.1 0.0 1.0 1 0 0 1 1 1 1 Photosystem I reaction centre subunit III Ribosomal_L5_C PF00673.16 AFZ64260.1 - 1.6e-37 127.1 0.0 2.8e-37 126.3 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 AFZ64260.1 - 3.4e-16 58.7 0.8 5.7e-16 58.0 0.3 1.6 2 0 0 2 2 2 1 Ribosomal protein L5 DUF2862 PF11061.3 AFZ64260.1 - 0.048 13.3 0.4 0.23 11.2 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2862) Ribosomal_L6 PF00347.18 AFZ64261.1 - 7.3e-34 116.1 4.0 1.2e-19 70.5 0.3 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Lipocalin_6 PF13944.1 AFZ64261.1 - 0.02 15.0 0.4 1.5 8.9 0.0 2.2 1 1 0 2 2 2 0 Lipocalin-like domain Ribosomal_S5_C PF03719.10 AFZ64262.1 - 8.1e-26 89.1 1.8 1.5e-25 88.2 1.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 AFZ64262.1 - 5.8e-21 74.0 5.4 9.5e-21 73.3 3.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain PsaL PF02605.10 AFZ64263.1 - 1.2e-45 154.8 0.7 1.5e-45 154.4 0.5 1.1 1 0 0 1 1 1 1 Photosystem I reaction centre subunit XI DUF4199 PF13858.1 AFZ64263.1 - 0.015 15.2 1.4 0.021 14.7 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF624 PF04854.9 AFZ64263.1 - 0.093 12.6 1.2 0.26 11.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF624 DUF4538 PF15061.1 AFZ64263.1 - 0.16 11.2 0.5 0.32 10.3 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) Transgly_assoc PF04226.8 AFZ64263.1 - 0.78 9.8 7.8 5 7.2 0.5 2.5 2 0 0 2 2 2 0 Transglycosylase associated protein DUF1230 PF06799.6 AFZ64264.1 - 2.4e-36 124.7 3.6 3.1e-36 124.4 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1230) DUF2207 PF09972.4 AFZ64264.1 - 7.6 4.9 6.9 0.42 9.1 1.2 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) TPR_1 PF00515.23 AFZ64265.1 - 5.9e-20 69.9 16.6 1.2e-08 34.2 0.8 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 AFZ64265.1 - 6.4e-19 67.3 15.1 1.5e-12 46.9 4.0 3.1 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.12 AFZ64265.1 - 2.8e-15 54.8 13.9 1.3e-06 27.8 0.2 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 AFZ64265.1 - 4.6e-14 52.1 10.7 5.6e-12 45.4 3.0 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 AFZ64265.1 - 3.5e-10 38.9 19.4 7.4e-05 22.2 1.5 4.2 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 AFZ64265.1 - 4.7e-08 32.6 9.8 0.0011 18.9 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 AFZ64265.1 - 1.2e-07 30.9 9.0 0.00046 19.7 0.1 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 AFZ64265.1 - 4.7e-07 29.5 7.7 0.002 17.9 0.2 4.4 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 AFZ64265.1 - 1.2e-06 29.0 2.2 0.00017 22.1 0.7 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 AFZ64265.1 - 1.6e-06 28.2 0.7 0.86 10.4 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat MIT PF04212.13 AFZ64265.1 - 1.3e-05 24.9 14.6 0.012 15.4 2.5 3.2 2 1 1 3 3 3 3 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 AFZ64265.1 - 0.00013 22.2 7.8 0.066 13.7 0.1 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat EST1_DNA_bind PF10373.4 AFZ64265.1 - 0.00014 21.2 5.4 0.00077 18.7 0.9 2.7 3 0 0 3 3 3 1 Est1 DNA/RNA binding domain MipA PF06629.7 AFZ64265.1 - 0.00088 18.7 0.5 0.0014 18.0 0.3 1.2 1 0 0 1 1 1 1 MltA-interacting protein MipA Apc3 PF12895.2 AFZ64265.1 - 0.0018 18.3 7.2 0.013 15.5 2.3 2.6 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 AFZ64265.1 - 0.0041 16.9 0.2 0.96 9.3 0.1 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 AFZ64265.1 - 0.0093 16.2 1.9 0.0093 16.2 1.3 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat DUF3808 PF10300.4 AFZ64265.1 - 0.011 14.3 2.7 0.013 14.0 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) Fis1_TPR_C PF14853.1 AFZ64265.1 - 0.013 15.3 2.3 0.013 15.3 1.6 2.8 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat PaREP1 PF05942.6 AFZ64265.1 - 0.025 14.4 3.1 0.38 10.6 2.1 2.1 1 1 0 1 1 1 0 Archaeal PaREP1/PaREP8 family DUF2225 PF09986.4 AFZ64265.1 - 0.057 12.8 8.9 0.061 12.7 1.3 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) UPF0154 PF03672.8 AFZ64265.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) SPO22 PF08631.5 AFZ64265.1 - 0.22 10.5 4.5 0.085 11.9 0.8 2.0 2 1 1 3 3 3 0 Meiosis protein SPO22/ZIP4 like Cytochrom_C550 PF14495.1 AFZ64266.1 - 1e-60 203.1 0.0 1.1e-60 202.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c-550 domain Cytochrom_C PF00034.16 AFZ64266.1 - 2.6e-06 28.1 0.0 3.5e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 AFZ64266.1 - 1.1e-05 25.4 0.0 5.4e-05 23.2 0.0 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III ATP-synt_B PF00430.13 AFZ64267.1 - 2.7e-11 43.3 10.0 8e-11 41.8 6.9 1.7 1 1 0 1 1 1 1 ATP synthase B/B' CF(0) AAA_27 PF13514.1 AFZ64267.1 - 0.0056 14.4 1.6 0.007 14.1 1.1 1.0 1 0 0 1 1 1 1 AAA domain DUF2634 PF10934.3 AFZ64267.1 - 0.011 15.5 2.2 0.015 15.0 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2634) Nic96 PF04097.9 AFZ64267.1 - 0.012 13.7 2.7 0.013 13.6 0.9 1.5 1 1 0 1 1 1 0 Nup93/Nic96 T2SM PF04612.7 AFZ64267.1 - 0.035 13.9 0.3 0.056 13.2 0.2 1.4 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein M Citrate_ly_lig PF08218.6 AFZ64267.1 - 0.055 12.9 0.5 0.075 12.4 0.4 1.3 1 0 0 1 1 1 0 Citrate lyase ligase C-terminal domain Cas_Csa5 PF09702.5 AFZ64267.1 - 0.13 12.3 1.9 0.18 11.8 1.3 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa5) NADHdeh_related PF10125.4 AFZ64267.1 - 0.13 11.3 0.1 0.24 10.5 0.1 1.4 1 0 0 1 1 1 0 NADH dehydrogenase I, subunit N related protein ASD2 PF08687.6 AFZ64267.1 - 3.5 6.8 9.4 4.9 6.3 6.5 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Cytochrom_B_C PF00032.12 AFZ64268.1 - 1.1e-18 67.3 0.6 1.8e-18 66.6 0.4 1.3 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD Ribosomal_S7 PF00177.16 AFZ64269.1 - 1.9e-50 170.2 1.4 2.1e-50 170.1 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e TMP-TENI PF02581.12 AFZ64269.1 - 0.12 11.5 0.0 0.39 9.8 0.0 1.7 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI Ribosomal_L22 PF00237.14 AFZ64270.1 - 4e-33 113.5 0.7 5.4e-33 113.0 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_L21p PF00829.16 AFZ64271.1 - 3.1e-15 56.0 0.0 1.6e-11 44.1 0.0 2.4 1 1 1 2 2 2 2 Ribosomal prokaryotic L21 protein Ribosomal_L13 PF00572.13 AFZ64272.1 - 2.9e-45 153.4 0.1 3.3e-45 153.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 Ribosomal_L11_N PF03946.9 AFZ64273.1 - 1e-28 98.5 0.4 1.3e-27 95.0 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 AFZ64273.1 - 3.4e-26 91.1 1.9 5.8e-26 90.4 1.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain ATP-synt_DE_N PF02823.11 AFZ64274.1 - 1.1e-21 76.3 0.2 1.5e-21 75.9 0.1 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ATP-synt_DE PF00401.15 AFZ64274.1 - 1.6e-05 24.7 2.0 2.3e-05 24.1 1.4 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, long alpha-helix domain COG5 PF10392.4 AFZ64274.1 - 0.0039 17.1 0.2 0.0064 16.4 0.1 1.3 1 0 0 1 1 1 1 Golgi transport complex subunit 5 CorA PF01544.13 AFZ64274.1 - 0.022 13.7 0.3 0.021 13.8 0.2 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Ribosomal_L16 PF00252.13 AFZ64275.1 - 1.9e-48 163.5 1.1 2.1e-48 163.4 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e PsaD PF02531.11 AFZ64276.1 - 6.8e-59 197.0 0.0 7.9e-59 196.8 0.0 1.0 1 0 0 1 1 1 1 PsaD Ribosomal_S9 PF00380.14 AFZ64277.1 - 9.2e-40 135.6 0.5 1e-39 135.4 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L20 PF00453.13 AFZ64278.1 - 1.2e-42 144.1 5.4 1.6e-42 143.8 3.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L20 Ribosomal_S8 PF00410.14 AFZ64279.1 - 3.9e-42 143.1 0.2 4.4e-42 142.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S8 DUF1473 PF07341.6 AFZ64279.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1473) Ribosomal_L12 PF00542.14 AFZ64280.1 - 3.8e-29 100.4 10.9 4e-28 97.2 4.1 2.2 2 1 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain DUF4375 PF14300.1 AFZ64280.1 - 0.022 14.7 0.1 1.7 8.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) DUF128 PF01995.11 AFZ64280.1 - 0.05 12.5 0.0 0.077 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF128 DUF2551 PF10826.3 AFZ64280.1 - 0.061 13.2 0.1 0.31 10.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2551) Ribosomal_S11 PF00411.14 AFZ64281.1 - 6.7e-40 135.6 1.2 7.7e-40 135.4 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 Ribosomal_L18p PF00861.17 AFZ64281.1 - 0.016 15.4 0.3 0.018 15.2 0.2 1.1 1 0 0 1 1 1 0 Ribosomal L18p/L5e family ELFV_dehydrog PF00208.16 AFZ64281.1 - 0.021 14.3 0.5 0.05 13.1 0.3 1.6 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Ribosom_S12_S23 PF00164.20 AFZ64282.1 - 1.5e-53 179.3 2.4 1.7e-53 179.1 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S13 PF00416.17 AFZ64283.1 - 3.1e-38 130.5 0.7 3.6e-38 130.2 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 H2TH PF06831.9 AFZ64283.1 - 0.0013 18.4 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.6 AFZ64283.1 - 0.0019 16.8 0.0 0.002 16.7 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) YqzH PF14164.1 AFZ64283.1 - 0.096 12.6 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 YqzH-like protein Ribosomal_L19 PF01245.15 AFZ64284.1 - 6.3e-32 109.7 0.9 7.5e-32 109.4 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L19 Ribosomal_L14 PF00238.14 AFZ64285.1 - 1.3e-49 167.0 1.1 1.4e-49 166.9 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Cytochrome_CBB3 PF13442.1 AFZ64286.1 - 2.9e-17 62.5 0.0 3.6e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 AFZ64286.1 - 4.4e-09 35.9 0.1 1.2e-06 28.0 0.0 2.1 1 1 1 2 2 2 2 Cytochrome c-550 domain Cytochrom_C PF00034.16 AFZ64286.1 - 5.3e-09 36.7 0.1 1.2e-08 35.6 0.1 1.5 1 1 0 1 1 1 1 Cytochrome c Ribosomal_L23 PF00276.15 AFZ64287.1 - 2.2e-23 82.0 0.2 2.8e-23 81.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L23 Hph PF13694.1 AFZ64288.1 - 0.092 12.7 2.3 0.13 12.2 1.6 1.5 1 1 0 1 1 1 0 Sec63/Sec62 complex-interacting family Glyco_hydro_42C PF08533.5 AFZ64288.1 - 0.092 12.2 0.2 0.24 10.9 0.1 1.7 1 1 0 1 1 1 0 Beta-galactosidase C-terminal domain FACT-Spt16_Nlob PF14826.1 AFZ64288.1 - 0.12 11.9 2.6 0.15 11.6 1.7 1.4 1 1 0 1 1 1 0 FACT complex subunit SPT16 N-terminal lobe domain Ribosomal_S10 PF00338.17 AFZ64289.1 - 3.5e-20 71.6 0.1 6.6e-20 70.7 0.1 1.4 1 1 0 1 1 1 1 Ribosomal protein S10p/S20e Ribosomal_L27 PF01016.14 AFZ64290.1 - 1.1e-35 121.2 3.9 1.3e-35 120.9 2.7 1.1 1 0 0 1 1 1 1 Ribosomal L27 protein Ycf54 PF10674.4 AFZ64291.1 - 4.9e-30 103.4 0.6 5.6e-30 103.3 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2488) Ribosomal_S6 PF01250.12 AFZ64292.1 - 2.3e-11 43.3 0.0 2.6e-11 43.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S6 Ribosomal_L18p PF00861.17 AFZ64293.1 - 3e-33 114.5 0.0 3.3e-33 114.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal L18p/L5e family Fer2 PF00111.22 AFZ64294.1 - 8e-20 70.3 0.5 1e-19 70.0 0.3 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain WAK_assoc PF14380.1 AFZ64294.1 - 0.039 14.4 1.1 0.24 11.9 0.4 2.0 1 1 1 2 2 2 0 Wall-associated receptor kinase C-terminal Zn_Tnp_IS91 PF14319.1 AFZ64294.1 - 0.081 12.4 0.1 0.13 11.7 0.0 1.4 1 1 0 1 1 1 0 Transposase zinc-binding domain Ycf66_N PF07444.6 AFZ64295.1 - 4.9e-34 115.9 4.6 5.6e-34 115.7 3.2 1.0 1 0 0 1 1 1 1 Ycf66 protein N-terminus DUF368 PF04018.8 AFZ64295.1 - 0.03 13.5 0.8 0.031 13.4 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF368) Ribosomal_S14 PF00253.16 AFZ64296.1 - 9.2e-25 85.7 0.4 1.7e-24 84.9 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4391 PF14335.1 AFZ64296.1 - 0.0065 15.8 3.3 0.0085 15.5 2.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4391) DUF2499 PF10693.4 AFZ64297.1 - 6.8e-25 86.9 9.7 7.6e-25 86.7 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2499) DUF3624 PF12292.3 AFZ64297.1 - 0.047 14.0 5.0 0.052 13.9 2.8 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3624) zf-DHHC PF01529.15 AFZ64297.1 - 9.3 5.6 8.3 12 5.2 5.7 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Ribosomal_S20p PF01649.13 AFZ64298.1 - 7.6e-23 80.6 14.4 9e-23 80.4 10.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S20 Viral_DNA_bp PF00747.12 AFZ64298.1 - 0.028 11.6 1.6 0.03 11.5 1.1 1.0 1 0 0 1 1 1 0 ssDNA binding protein Mor PF08765.6 AFZ64298.1 - 0.13 12.0 1.0 0.34 10.7 0.1 1.9 1 1 1 2 2 2 0 Mor transcription activator family DUF1825 PF08855.5 AFZ64298.1 - 0.2 11.6 1.2 0.37 10.7 0.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1825) Ribosomal_S19 PF00203.16 AFZ64299.1 - 1.4e-32 111.0 0.2 1.7e-32 110.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 RuBisCO_small PF00101.15 AFZ64300.1 - 1.8e-13 50.1 0.0 3e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Ribulose bisphosphate carboxylase, small chain Ribosomal_S3_C PF00189.15 AFZ64301.1 - 2e-25 88.7 0.1 2.4e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain Ribosomal_S17 PF00366.15 AFZ64302.1 - 2.9e-25 88.1 1.5 3.2e-25 87.9 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_S16 PF00886.14 AFZ64303.1 - 6.5e-20 70.6 0.1 8e-20 70.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 ATP-synt_C PF00137.16 AFZ64304.1 - 1.4e-23 82.5 9.4 1.6e-23 82.3 6.5 1.1 1 0 0 1 1 1 1 ATP synthase subunit C Cytochrom_B559a PF00284.15 AFZ64305.1 - 1.6e-24 85.1 0.7 2e-24 84.7 0.5 1.2 1 0 0 1 1 1 1 Lumenal portion of Cytochrome b559, alpha (gene psbE) subunit Cytochrom_B559 PF00283.14 AFZ64305.1 - 5.5e-15 54.3 1.7 8.1e-15 53.7 1.1 1.3 1 0 0 1 1 1 1 Cytochrome b559, alpha (gene psbE) and beta (gene psbF)subunits Cg6151-P PF10233.4 AFZ64305.1 - 0.037 14.0 0.0 0.046 13.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein CG6151-P Fer4 PF00037.22 AFZ64306.1 - 8.3e-15 53.6 11.7 2.2e-07 30.1 1.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.1 AFZ64306.1 - 2.1e-10 40.2 27.6 5.6e-07 29.2 12.1 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.2 AFZ64306.1 - 5.1e-10 38.7 12.3 8.6e-06 25.4 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 AFZ64306.1 - 7.3e-10 39.0 15.0 1.1e-09 38.5 10.4 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 AFZ64306.1 - 2.9e-09 36.6 14.1 6.1e-09 35.6 9.8 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 AFZ64306.1 - 5.6e-09 36.1 14.4 8.7e-09 35.5 10.0 1.3 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 AFZ64306.1 - 1.6e-08 33.9 20.5 4.7e-05 23.0 2.4 2.5 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_18 PF13746.1 AFZ64306.1 - 2.3e-08 34.3 14.0 0.00054 20.3 2.7 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 AFZ64306.1 - 9.7e-08 32.6 9.7 0.0017 19.0 2.1 2.1 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_4 PF12800.2 AFZ64306.1 - 1.3e-07 31.3 20.7 0.00041 20.4 3.3 2.4 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 AFZ64306.1 - 3.7e-07 30.3 9.9 0.0031 17.8 1.4 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.1 AFZ64306.1 - 2.2e-06 27.6 28.0 0.0001 22.2 11.6 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.1 AFZ64306.1 - 6.6e-06 26.6 10.1 0.00059 20.3 1.1 2.1 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 AFZ64306.1 - 2.6e-05 24.4 22.0 0.0018 18.6 4.0 2.5 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_13 PF13370.1 AFZ64306.1 - 0.00034 20.9 12.4 0.015 15.6 1.9 2.2 2 0 0 2 2 2 2 4Fe-4S single cluster domain ThiS PF02597.15 AFZ64307.1 - 0.00012 22.4 0.0 0.00017 21.9 0.0 1.3 1 1 0 1 1 1 1 ThiS family Sialidase_penC PF12135.3 AFZ64307.1 - 0.3 10.7 1.7 0.37 10.4 0.3 1.8 2 0 0 2 2 2 0 Sialidase enzyme penultimate C terminal domain Ribosomal_L31 PF01197.13 AFZ64308.1 - 1.6e-24 85.6 0.3 1.8e-24 85.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L31 Ribosomal_S18 PF01084.15 AFZ64309.1 - 9.4e-19 67.0 0.5 1.2e-18 66.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S18 Ribosomal_L29 PF00831.18 AFZ64310.1 - 4.5e-09 35.8 0.9 5.3e-09 35.6 0.6 1.1 1 0 0 1 1 1 1 Ribosomal L29 protein DUF1891 PF09004.5 AFZ64310.1 - 0.051 12.9 1.9 0.089 12.1 1.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1891) PsbH PF00737.15 AFZ64311.1 - 5.1e-30 102.8 2.0 6.1e-30 102.5 1.4 1.1 1 0 0 1 1 1 1 Photosystem II 10 kDa phosphoprotein PSI_PsaE PF02427.12 AFZ64312.1 - 1.4e-31 107.6 1.6 1.5e-31 107.4 1.1 1.0 1 0 0 1 1 1 1 Photosystem I reaction centre subunit IV / PsaE Ribosomal_L33 PF00471.15 AFZ64313.1 - 1.9e-22 79.2 8.8 2.5e-22 78.8 6.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 RNA_POL_M_15KD PF02150.11 AFZ64313.1 - 0.0062 16.1 1.0 0.14 11.8 0.1 2.2 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit DUF1272 PF06906.6 AFZ64313.1 - 0.017 14.9 0.3 3 7.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DNA_ligase_ZBD PF03119.11 AFZ64313.1 - 0.027 14.1 1.1 0.038 13.6 0.3 1.6 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Zn-ribbon_8 PF09723.5 AFZ64313.1 - 0.041 13.8 1.3 0.91 9.5 0.1 2.1 2 0 0 2 2 2 0 Zinc ribbon domain HypA PF01155.14 AFZ64313.1 - 0.042 13.5 0.9 0.047 13.3 0.6 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family NOB1_Zn_bind PF08772.6 AFZ64313.1 - 0.053 13.3 5.6 0.88 9.4 3.9 2.2 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Lar_restr_allev PF14354.1 AFZ64313.1 - 0.13 12.6 1.4 4.2 7.7 0.1 2.1 1 1 1 2 2 2 0 Restriction alleviation protein Lar DZR PF12773.2 AFZ64313.1 - 0.26 11.1 4.1 2.1 8.2 3.0 2.0 1 1 1 2 2 2 0 Double zinc ribbon DUF866 PF05907.8 AFZ64313.1 - 0.29 10.6 2.1 0.3 10.5 1.4 1.0 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) DUF329 PF03884.9 AFZ64313.1 - 0.33 10.5 1.7 12 5.5 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF329) GFA PF04828.9 AFZ64313.1 - 0.6 10.0 5.7 4 7.4 4.0 1.9 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme zf-ISL3 PF14690.1 AFZ64313.1 - 1.7 8.7 7.4 0.73 9.9 0.9 2.7 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-ribbon_3 PF13248.1 AFZ64313.1 - 3.1 7.1 5.6 0.87 8.8 1.2 1.8 1 1 1 2 2 1 0 zinc-ribbon domain Ribosomal_L35p PF01632.14 AFZ64314.1 - 1.6e-16 59.9 11.8 1.7e-16 59.8 8.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L35 DUF1819 PF08849.6 AFZ64314.1 - 0.026 13.9 0.3 0.028 13.8 0.2 1.1 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) DUF4093 PF13331.1 AFZ64314.1 - 0.14 12.3 0.4 0.15 12.2 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4093) Ycf9 PF01737.12 AFZ64315.1 - 1.4e-10 40.4 3.1 1.5e-10 40.3 2.1 1.0 1 0 0 1 1 1 1 YCF9 RSN1_TM PF13967.1 AFZ64315.1 - 0.04 13.4 0.1 0.042 13.4 0.1 1.1 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport ABC2_membrane_5 PF13346.1 AFZ64315.1 - 0.044 13.0 2.0 0.046 13.0 1.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein ODV-E18 PF10717.4 AFZ64315.1 - 0.28 10.6 1.5 0.26 10.7 1.0 1.1 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Yip1 PF04893.12 AFZ64315.1 - 0.32 10.4 5.2 0.35 10.3 3.6 1.1 1 0 0 1 1 1 0 Yip1 domain SecG PF03840.9 AFZ64315.1 - 5.4 6.8 7.2 9.7 6.0 5.0 1.6 1 1 0 1 1 1 0 Preprotein translocase SecG subunit DUF401 PF04165.7 AFZ64316.1 - 0.1 11.5 1.6 0.11 11.5 1.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF401) DUF4149 PF13664.1 AFZ64316.1 - 0.11 12.5 1.1 0.13 12.3 0.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) DUF3753 PF12575.3 AFZ64316.1 - 2.6 7.8 6.3 1.9 8.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) Ribosomal_L32p PF01783.18 AFZ64317.1 - 2.3e-07 30.8 2.5 2.6e-07 30.7 1.8 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family PsbN PF02468.10 AFZ64318.1 - 3.2e-19 68.2 0.1 3.5e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Photosystem II reaction centre N protein (psbN) Ribosomal_L34 PF00468.12 AFZ64319.1 - 6e-15 54.6 12.8 6.7e-15 54.4 8.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L34 Ribosomal_L29 PF00831.18 AFZ64319.1 - 0.26 10.9 4.8 0.31 10.7 3.3 1.1 1 0 0 1 1 1 0 Ribosomal L29 protein DUF4629 PF15442.1 AFZ64319.1 - 0.38 10.8 4.0 0.42 10.7 2.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) PSI_PsaJ PF01701.13 AFZ64320.1 - 8.8e-24 82.9 0.7 1e-23 82.7 0.5 1.1 1 0 0 1 1 1 1 Photosystem I reaction centre subunit IX / PsaJ DUF2324 PF10086.4 AFZ64320.1 - 0.12 11.5 0.0 0.12 11.5 0.0 1.0 1 0 0 1 1 1 0 Putative membrane peptidase family (DUF2324) PsbK PF02533.10 AFZ64321.1 - 2.9e-23 81.5 7.7 3.1e-23 81.4 5.3 1.0 1 0 0 1 1 1 1 Photosystem II 4 kDa reaction centre component Cytochrom_B559 PF00283.14 AFZ64322.1 - 9.9e-19 66.3 2.3 1.3e-18 65.9 1.6 1.2 1 0 0 1 1 1 1 Cytochrome b559, alpha (gene psbE) and beta (gene psbF)subunits PsbJ PF01788.12 AFZ64323.1 - 1.6e-19 69.1 9.1 1.6e-19 69.1 6.3 1.0 1 0 0 1 1 1 1 PsbJ PsbX PF06596.6 AFZ64324.1 - 1.2e-18 66.5 3.7 1.2e-18 66.4 2.5 1.0 1 0 0 1 1 1 1 Photosystem II reaction centre X protein (PsbX) UPF0114 PF03350.11 AFZ64324.1 - 0.09 12.7 0.1 0.09 12.7 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein family, UPF0114 PsbI PF02532.9 AFZ64325.1 - 8.2e-20 70.1 0.9 9.4e-20 69.9 0.6 1.0 1 0 0 1 1 1 1 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Ribosomal_L36 PF00444.13 AFZ64326.1 - 7.3e-18 64.2 13.0 7.8e-18 64.1 9.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L36 PsbY PF06298.6 AFZ64327.1 - 1.2e-15 56.6 1.0 1.3e-15 56.6 0.7 1.0 1 0 0 1 1 1 1 Photosystem II protein Y (PsbY) Tad PF13400.1 AFZ64327.1 - 0.027 14.4 0.2 0.033 14.2 0.1 1.1 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like PLDc_N PF13396.1 AFZ64327.1 - 0.094 12.4 3.3 0.11 12.1 2.3 1.1 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal PetG PF02529.10 AFZ64328.1 - 8.7e-21 73.1 2.5 9e-21 73.1 1.8 1.0 1 0 0 1 1 1 1 Cytochrome B6-F complex subunit 5 COX14 PF14880.1 AFZ64328.1 - 0.025 14.2 0.7 0.028 14.0 0.5 1.1 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Na_H_antiport_1 PF06965.7 AFZ64328.1 - 0.06 12.1 0.3 0.06 12.1 0.2 1.0 1 0 0 1 1 1 0 Na+/H+ antiporter 1 Yip1 PF04893.12 AFZ64328.1 - 0.1 12.0 0.8 0.091 12.2 0.6 1.0 1 0 0 1 1 1 0 Yip1 domain PsbJ PF01788.12 AFZ64328.1 - 0.12 11.8 2.3 0.13 11.8 1.6 1.1 1 0 0 1 1 1 0 PsbJ PsbT PF01405.12 AFZ64329.1 - 1e-18 66.5 7.3 1.1e-18 66.4 5.0 1.0 1 0 0 1 1 1 1 Photosystem II reaction centre T protein YlaH PF14036.1 AFZ64329.1 - 0.018 15.1 0.9 0.018 15.1 0.6 1.0 1 0 0 1 1 1 0 YlaH-like protein PetN PF03742.9 AFZ64330.1 - 2.9e-15 55.5 9.1 3.1e-15 55.4 6.3 1.0 1 0 0 1 1 1 1 PetN DUF4094 PF13334.1 AFZ64330.1 - 0.14 12.5 0.9 0.15 12.4 0.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Oxidored_q1 PF00361.15 AFZ64331.1 - 1.9e-85 286.3 17.9 1.9e-85 286.3 12.4 3.9 4 2 0 4 4 4 1 NADH-Ubiquinone/plastoquinone (complex I), various chains Oxidored_q1_N PF00662.15 AFZ64331.1 - 9.3e-24 82.7 7.7 9.3e-24 82.7 5.3 2.8 2 0 0 2 2 2 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus NADH5_C PF06455.6 AFZ64331.1 - 2.1e-12 46.8 12.7 2.1e-12 46.8 8.8 4.5 3 2 0 3 3 3 1 NADH dehydrogenase subunit 5 C-terminus Oxidored_q1 PF00361.15 AFZ64332.1 - 6.1e-74 248.6 34.1 6.1e-74 248.6 23.6 3.7 2 1 2 4 4 4 1 NADH-Ubiquinone/plastoquinone (complex I), various chains ATP-synt_ab PF00006.20 AFZ64333.1 - 1.4e-64 217.5 0.0 1.9e-64 217.1 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 AFZ64333.1 - 9.7e-14 51.8 0.0 2.2e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 AFZ64333.1 - 9.1e-11 41.8 1.3 2.2e-10 40.6 0.9 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 AFZ64333.1 - 2.9e-08 33.4 2.2 3.4e-07 30.0 1.5 2.3 1 1 1 2 2 2 1 HAS barrel domain Molybdopterin PF00384.17 AFZ64334.1 - 3.9e-44 151.0 0.0 1.2e-42 146.1 0.0 2.3 1 1 0 1 1 1 1 Molybdopterin oxidoreductase DUF1982 PF09326.6 AFZ64334.1 - 0.00018 21.5 0.1 0.00052 20.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) COX1 PF00115.15 AFZ64335.1 - 8.8e-174 578.3 57.0 1.1e-173 578.0 39.5 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I COX1 PF00115.15 AFZ64336.1 - 2.8e-174 579.9 57.3 3.4e-174 579.6 39.7 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Oxidored_q1 PF00361.15 AFZ64337.1 - 7.9e-62 208.9 32.1 7.9e-62 208.9 22.3 3.6 3 1 0 3 3 3 1 NADH-Ubiquinone/plastoquinone (complex I), various chains Ribosomal_S3_C PF00189.15 AFZ64338.1 - 3.2e-18 65.7 1.1 3.2e-18 65.7 0.7 2.2 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain Complex1_49kDa PF00346.14 AFZ64339.1 - 8.4e-129 428.3 0.0 1e-128 428.0 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Cytochrom_B_N_2 PF13631.1 AFZ64340.1 - 7.5e-55 185.2 16.7 7.5e-55 185.2 11.6 2.0 3 0 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.12 AFZ64340.1 - 1.1e-38 131.5 3.0 1.1e-38 131.5 2.1 3.1 3 1 0 3 3 3 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_N PF00033.14 AFZ64340.1 - 6.2e-12 45.2 25.3 6.2e-12 45.2 17.5 2.5 2 1 0 2 2 2 2 Cytochrome b(N-terminal)/b6/petB NADHdh PF00146.16 AFZ64341.1 - 1.9e-133 444.3 20.7 2.2e-133 444.1 14.3 1.0 1 0 0 1 1 1 1 NADH dehydrogenase Peptidase_M50 PF02163.17 AFZ64341.1 - 0.025 13.5 0.0 0.068 12.1 0.0 1.9 1 1 0 1 1 1 0 Peptidase family M50 DUF4083 PF13314.1 AFZ64341.1 - 1.9 8.3 7.2 0.22 11.3 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) COX2 PF00116.15 AFZ64342.1 - 5e-51 171.5 0.2 1.1e-43 147.8 0.0 2.3 1 1 1 2 2 2 2 Cytochrome C oxidase subunit II, periplasmic domain COX2_TM PF02790.10 AFZ64342.1 - 6.8e-26 90.0 2.1 1.6e-25 88.8 1.4 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, transmembrane domain Ribosomal_L2_C PF03947.13 AFZ64343.1 - 3.3e-54 182.1 2.1 5.7e-54 181.3 1.5 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 AFZ64343.1 - 2.2e-20 72.4 0.4 5.7e-20 71.0 0.1 1.8 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain COX3 PF00510.13 AFZ64344.1 - 3.2e-122 406.9 29.9 3.7e-122 406.7 20.7 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III ATP-synt_A PF00119.15 AFZ64345.1 - 4.7e-52 176.6 31.3 6.7e-52 176.1 21.7 1.3 1 0 0 1 1 1 1 ATP synthase A chain S4 PF01479.20 AFZ64346.1 - 2.2e-10 39.7 0.0 4.7e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 S4 domain FERM_C PF09380.5 AFZ64346.1 - 0.89 9.8 4.8 5.8 7.2 0.1 2.3 2 0 0 2 2 2 0 FERM C-terminal PH-like domain TatC PF00902.13 AFZ64347.1 - 1.6e-33 115.9 39.7 1.6e-33 115.9 27.5 1.8 1 1 1 2 2 2 1 Sec-independent protein translocase protein (TatC) AIG1 PF04548.11 AFZ64348.1 - 0.041 12.9 0.8 0.41 9.7 0.0 2.2 1 1 1 2 2 2 0 AIG1 family DUF3750 PF12570.3 AFZ64348.1 - 0.11 12.7 0.1 0.2 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3750) AntA PF08346.7 AFZ64348.1 - 0.66 10.2 4.8 0.17 12.0 0.4 2.2 3 0 0 3 3 3 0 AntA/AntB antirepressor Ribosomal_S2 PF00318.15 AFZ64349.1 - 1e-26 93.4 1.7 2.3e-25 89.0 1.2 2.0 1 1 0 1 1 1 1 Ribosomal protein S2 Oxidored_q3 PF00499.15 AFZ64350.1 - 3.5e-25 88.4 34.2 6.1e-25 87.6 23.7 1.4 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Complex1_30kDa PF00329.14 AFZ64351.1 - 2e-33 114.7 0.0 2.6e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Ribosomal_L6 PF00347.18 AFZ64352.1 - 1.8e-11 44.3 0.0 1.5e-09 38.1 0.0 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_L5_C PF00673.16 AFZ64353.1 - 9e-08 31.7 0.1 1.7e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 AFZ64353.1 - 0.00047 19.8 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L5 Ribosomal_S11 PF00411.14 AFZ64354.1 - 7.5e-28 96.9 0.1 1.1e-27 96.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 DUF1394 PF07159.7 AFZ64354.1 - 0.12 11.5 0.3 0.19 10.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1394) Ribosomal_S7 PF00177.16 AFZ64355.1 - 3.6e-43 146.6 1.9 4e-43 146.5 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Tcf25 PF04910.9 AFZ64355.1 - 0.075 11.9 0.0 0.13 11.2 0.0 1.4 1 1 0 1 1 1 0 Transcriptional repressor TCF25 Ribosomal_L16 PF00252.13 AFZ64356.1 - 2.1e-42 144.0 0.3 2.4e-42 143.8 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_S13 PF00416.17 AFZ64357.1 - 1.8e-23 83.0 0.3 2.1e-23 82.7 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Ribosomal_L14 PF00238.14 AFZ64358.1 - 1.1e-38 131.7 4.2 1.2e-38 131.5 2.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Arc_PepC PF06819.6 AFZ64358.1 - 0.011 15.6 0.1 0.014 15.3 0.1 1.2 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminal Domain DUF1846 PF08903.6 AFZ64358.1 - 0.013 13.9 0.2 0.015 13.7 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1846) DUF4108 PF13390.1 AFZ64358.1 - 0.046 13.4 0.2 0.055 13.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4108) DNA_pol_B_palm PF14792.1 AFZ64358.1 - 0.14 12.1 0.5 0.23 11.5 0.4 1.5 1 1 0 1 1 1 0 DNA polymerase beta palm Oxidored_q4 PF00507.14 AFZ64359.1 - 2.7e-31 107.3 11.9 3.7e-31 106.9 8.3 1.3 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 DUF1279 PF06916.8 AFZ64359.1 - 0.067 13.5 1.0 0.099 12.9 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1279) DUF3937 PF13073.1 AFZ64359.1 - 0.093 12.6 0.2 0.093 12.6 0.1 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3937) DUF3270 PF11674.3 AFZ64359.1 - 3.7 7.6 11.8 0.74 9.8 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) zf-DHHC PF01529.15 AFZ64359.1 - 5.1 6.4 5.3 7.7 5.8 3.6 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase Ribosomal_S10 PF00338.17 AFZ64360.1 - 3.9e-13 49.0 0.5 4.5e-13 48.8 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Ribosomal_S14 PF00253.16 AFZ64361.1 - 8e-14 50.7 0.2 1.6e-13 49.7 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Ribosomal_S19 PF00203.16 AFZ64362.1 - 6.2e-17 60.9 0.2 1e-16 60.2 0.0 1.4 1 1 1 2 2 2 1 Ribosomal protein S19 ATP-synt_C PF00137.16 AFZ64363.1 - 4.8e-19 68.0 11.9 5.4e-19 67.8 8.3 1.0 1 0 0 1 1 1 1 ATP synthase subunit C MFS_3 PF05977.8 AFZ64363.1 - 0.27 9.3 4.8 0.28 9.2 3.3 1.0 1 0 0 1 1 1 0 Transmembrane secretion effector ABC2_membrane_4 PF12730.2 AFZ64363.1 - 0.32 10.1 5.0 0.39 9.8 3.5 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein UBN2_2 PF14227.1 EWM19899.1 - 3.5e-07 29.7 0.1 4.3e-07 29.5 0.1 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EWM19899.1 - 4.2e-05 23.3 0.1 4.9e-05 23.1 0.1 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Rop PF01815.11 EWM19899.1 - 0.053 12.9 0.1 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 Rop protein Pkinase PF00069.20 EWM19901.1 - 5.8e-18 64.9 0.2 6.5e-18 64.8 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM19901.1 - 2.6e-06 26.7 0.6 3e-06 26.4 0.5 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EWM19901.1 - 0.04 13.6 0.2 0.061 13.0 0.1 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family SIR2 PF02146.12 EWM19902.1 - 0.05 13.3 0.0 0.06 13.0 0.0 1.0 1 0 0 1 1 1 0 Sir2 family MMR_HSR1 PF01926.18 EWM19905.1 - 0.025 14.5 0.0 0.032 14.1 0.0 1.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase ketoacyl-synt PF00109.21 EWM19915.1 - 5.8e-37 127.5 1.1 6.8e-37 127.3 0.8 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.18 EWM19915.1 - 0.12 11.3 0.1 0.15 10.9 0.1 1.2 1 0 0 1 1 1 0 Thiolase, N-terminal domain RNB PF00773.14 EWM19922.1 - 2.9e-05 23.5 0.0 3.2e-05 23.3 0.0 1.0 1 0 0 1 1 1 1 RNB domain RVT_2 PF07727.9 EWM19924.1 - 8e-39 133.0 0.0 1e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNA_pol_I_A49 PF06870.7 EWM19924.1 - 0.05 12.1 0.0 0.071 11.6 0.0 1.2 1 0 0 1 1 1 0 A49-like RNA polymerase I associated factor Levi_coat PF01819.12 EWM19927.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Levivirus coat protein KAT11 PF08214.6 EWM19928.1 - 0.03 13.4 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Histone acetylation protein DUF448 PF04296.8 EWM19929.1 - 0.085 12.4 0.0 0.26 10.9 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF448) Lipoxygenase PF00305.14 EWM19931.1 - 8.2e-11 40.6 0.0 9.2e-11 40.4 0.0 1.0 1 0 0 1 1 1 1 Lipoxygenase DUF1759 PF03564.10 EWM19932.1 - 0.00042 20.1 0.3 0.0075 16.0 0.1 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1759) Cupin_8 PF13621.1 EWM19933.1 - 1.3e-05 24.8 0.0 1.8e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain ketoacyl-synt PF00109.21 EWM19936.1 - 1.2e-31 110.1 7.6 1.3e-31 110.0 5.3 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.18 EWM19936.1 - 0.001 18.0 1.3 0.0011 18.0 0.9 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EWM19936.1 - 0.0079 15.8 6.4 0.26 10.9 4.4 2.1 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PEP-utilisers_N PF05524.8 EWM19937.1 - 0.0019 17.9 6.3 0.0027 17.5 4.4 1.4 1 1 0 1 1 1 1 PEP-utilising enzyme, N-terminal BAAT_C PF08840.6 EWM19937.1 - 0.0044 16.7 0.1 0.0058 16.3 0.0 1.1 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Spc7 PF08317.6 EWM19937.1 - 0.032 12.8 1.9 0.041 12.5 1.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein MR_MLE_N PF02746.11 EWM19937.1 - 0.26 11.2 3.0 0.41 10.6 2.1 1.2 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Phage_Mu_Gam PF07352.7 EWM19937.1 - 0.54 9.7 8.3 1.9 8.0 5.8 1.9 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein DUF4407 PF14362.1 EWM19937.1 - 3 6.7 10.8 1.9 7.4 6.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TMEM18 PF14770.1 EWM19943.1 - 0.14 11.6 0.7 0.19 11.2 0.5 1.1 1 0 0 1 1 1 0 Transmembrane protein 18 ABC_tran PF00005.22 EWM19945.1 - 1.2e-06 28.9 0.0 1.5e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EWM19945.1 - 0.0025 17.8 0.0 0.0038 17.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 EWM19945.1 - 0.033 14.1 0.2 0.49 10.3 0.2 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit zf-CCHC PF00098.18 EWM19950.1 - 0.006 16.4 4.7 0.006 16.4 3.2 2.0 2 0 0 2 2 2 1 Zinc knuckle eIF3g PF12353.3 EWM19950.1 - 0.012 15.4 0.4 0.02 14.8 0.3 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_3 PF13917.1 EWM19950.1 - 0.094 12.4 3.9 0.19 11.5 2.7 1.5 1 1 0 1 1 1 0 Zinc knuckle ketoacyl-synt PF00109.21 EWM19952.1 - 4.1e-42 144.4 1.7 4.1e-42 144.4 1.2 1.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EWM19952.1 - 1.8e-12 47.1 0.2 4.7e-12 45.7 0.1 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EWM19952.1 - 0.00089 18.3 0.1 0.0065 15.4 0.0 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain DUF1455 PF07306.6 EWM19952.1 - 0.0037 17.3 1.2 0.0038 17.2 0.2 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1455) FAP PF07174.6 EWM19955.1 - 0.12 11.6 12.4 0.14 11.4 8.6 1.0 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) ORC6 PF05460.8 EWM19955.1 - 2.5 7.0 10.4 3.3 6.7 7.2 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF605 PF04652.11 EWM19955.1 - 7.3 5.8 13.7 8.1 5.7 9.5 1.0 1 0 0 1 1 1 0 Vta1 like DUF566 PF04484.7 EWM19955.1 - 7.7 5.9 12.6 8.5 5.7 8.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Mito_carr PF00153.22 EWM19958.1 - 2.4e-06 27.1 0.0 0.0093 15.6 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF4244 PF14029.1 EWM19959.1 - 0.052 12.6 0.0 0.092 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4244) Glyco_hydro_9 PF00759.14 EWM19961.1 - 7.5e-11 41.5 3.1 8.3e-11 41.4 2.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Sulfotransfer_3 PF13469.1 EWM19967.1 - 0.02 15.8 1.1 0.24 12.3 0.8 2.1 1 1 0 1 1 1 0 Sulfotransferase family DEAD PF00270.24 EWM19969.1 - 1e-21 77.1 0.0 1.2e-21 76.9 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase CMS1 PF14617.1 EWM19969.1 - 2.9e-05 23.2 0.0 3e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit PseudoU_synth_2 PF00849.17 EWM19971.1 - 2.5e-05 24.1 0.0 3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase Myosin_tail_1 PF01576.14 EWM19972.1 - 0.0021 15.8 4.4 0.0026 15.5 3.0 1.1 1 0 0 1 1 1 1 Myosin tail Pox_A_type_inc PF04508.7 EWM19972.1 - 0.055 13.2 1.2 6.9 6.7 0.9 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Fmp27_WPPW PF10359.4 EWM19972.1 - 0.055 11.8 0.1 0.062 11.7 0.1 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain IncA PF04156.9 EWM19972.1 - 0.067 12.7 1.3 0.084 12.4 0.9 1.1 1 0 0 1 1 1 0 IncA protein FliJ PF02050.11 EWM19972.1 - 0.086 12.9 1.8 0.12 12.4 1.3 1.2 1 0 0 1 1 1 0 Flagellar FliJ protein DUF972 PF06156.8 EWM19972.1 - 0.18 12.1 1.0 0.24 11.7 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF4140 PF13600.1 EWM19972.1 - 0.19 12.2 2.8 0.46 10.9 1.9 1.7 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) CENP-Q PF13094.1 EWM19972.1 - 0.21 11.6 6.2 0.33 10.9 4.3 1.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Spc7 PF08317.6 EWM19972.1 - 0.3 9.7 2.3 0.34 9.5 1.6 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein GAS PF13851.1 EWM19972.1 - 0.35 10.0 2.7 0.4 9.8 1.9 1.0 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Thiolase_N PF00108.18 EWM19975.1 - 0.0023 16.9 0.0 0.0025 16.8 0.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain PRP8_domainIV PF12134.3 EWM19977.1 - 9.5e-29 100.3 2.1 1e-28 100.2 1.4 1.0 1 0 0 1 1 1 1 PRP8 domain IV core gag_pre-integrs PF13976.1 EWM19981.1 - 1.7e-05 24.3 0.0 3.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain PEP-utilisers_N PF05524.8 EWM19982.1 - 0.11 12.2 8.4 0.16 11.7 5.8 1.4 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal Mito_fiss_reg PF05308.6 EWM19985.1 - 0.24 10.7 3.4 0.29 10.4 2.4 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF1759 PF03564.10 EWM19986.1 - 0.044 13.6 0.2 0.71 9.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) UBN2_2 PF14227.1 EWM19986.1 - 0.12 11.9 0.0 0.3 10.6 0.0 1.6 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type BNR_3 PF13859.1 EWM19987.1 - 0.00061 18.9 5.6 0.13 11.3 0.3 2.0 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.15 EWM19987.1 - 0.0068 16.0 9.5 0.054 13.3 1.0 3.8 5 0 0 5 5 5 2 BNR/Asp-box repeat PSII_BNR PF14870.1 EWM19987.1 - 0.016 14.1 7.2 0.22 10.4 5.0 1.9 1 1 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 BNR_2 PF13088.1 EWM19987.1 - 0.027 13.7 5.7 0.51 9.5 0.7 2.2 1 1 1 2 2 2 0 BNR repeat-like domain Rad4 PF03835.10 EWM19987.1 - 0.033 13.5 0.3 1.8 7.9 0.0 2.0 1 1 1 2 2 2 0 Rad4 transglutaminase-like domain Cerato-platanin PF07249.7 EWM19987.1 - 0.048 13.6 1.5 2.7 8.0 0.6 2.1 1 1 1 2 2 2 0 Cerato-platanin DUF4185 PF13810.1 EWM19987.1 - 0.062 12.2 7.4 0.41 9.5 0.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4185) SKG6 PF08693.5 EWM19987.1 - 0.76 9.1 3.7 2.6 7.4 0.3 2.4 2 0 0 2 2 2 0 Transmembrane alpha-helix domain BAAT_C PF08840.6 EWM19988.1 - 0.0062 16.2 0.0 0.0079 15.9 0.0 1.1 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal PEP-utilisers_N PF05524.8 EWM19988.1 - 0.031 14.0 5.5 0.053 13.3 3.8 1.5 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal Phage_Mu_Gam PF07352.7 EWM19988.1 - 0.076 12.5 6.6 0.048 13.1 3.1 1.5 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein ABC2_membrane_3 PF12698.2 EWM19989.1 - 1e-20 74.1 1.8 1.2e-20 73.8 1.2 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein XRCC1_N PF01834.11 EWM19989.1 - 0.07 12.6 0.0 0.094 12.1 0.0 1.2 1 0 0 1 1 1 0 XRCC1 N terminal domain Cyclin_C PF02984.14 EWM19991.1 - 5.8e-22 77.8 0.1 7.4e-22 77.4 0.1 1.1 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N PF00134.18 EWM19991.1 - 1.8e-05 24.3 0.0 0.0076 15.8 0.0 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain PEP-utilisers_N PF05524.8 EWM19993.1 - 0.0045 16.7 0.7 0.0072 16.1 0.5 1.4 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal Cullin PF00888.17 EWM19994.1 - 1.7e-25 89.6 1.4 2.2e-25 89.2 1.0 1.0 1 0 0 1 1 1 1 Cullin family MSC PF09402.5 EWM19994.1 - 2.5 6.7 5.6 4.4 5.9 3.9 1.3 1 1 0 1 1 1 0 Man1-Src1p-C-terminal domain U5_2-snRNA_bdg PF10597.4 EWM19995.1 - 2.8e-31 107.9 1.2 3.1e-31 107.7 0.8 1.0 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 Rrn6 PF10214.4 EWM19995.1 - 0.0062 14.7 0.1 0.0072 14.4 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor GIIM PF08388.6 EWM19995.1 - 0.049 13.4 0.0 0.068 12.9 0.0 1.2 1 0 0 1 1 1 0 Group II intron, maturase-specific domain ketoacyl-synt PF00109.21 EWM19998.1 - 7.4e-61 205.8 4.3 1.2e-60 205.1 3.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EWM19998.1 - 6.9e-12 45.2 0.3 1.3e-11 44.3 0.0 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EWM19998.1 - 2.3e-05 23.5 0.5 4e-05 22.7 0.2 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EWM19998.1 - 0.059 13.0 0.4 0.059 13.0 0.3 2.3 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III p450 PF00067.17 EWM20002.1 - 2.4e-06 26.3 0.0 2.6e-06 26.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cnl2_NKP2 PF09447.5 EWM20002.1 - 0.094 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Cnl2/NKP2 family protein ABC_tran PF00005.22 EWM20003.1 - 2.6e-09 37.4 0.0 3e-09 37.3 0.0 1.0 1 0 0 1 1 1 1 ABC transporter SbcCD_C PF13558.1 EWM20003.1 - 0.15 12.0 0.5 2.7 7.9 0.0 2.1 1 1 1 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF1841 PF08897.6 EWM20004.1 - 0.049 13.4 0.4 0.58 9.9 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1841) rve PF00665.21 EWM20005.1 - 3.7e-15 56.0 0.0 5.3e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain PEP-utilisers_N PF05524.8 EWM20009.1 - 0.01 15.6 4.0 0.015 15.0 2.8 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal BAAT_C PF08840.6 EWM20009.1 - 0.036 13.7 0.0 0.049 13.3 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Phage_Mu_Gam PF07352.7 EWM20009.1 - 1.2 8.6 7.6 1.5 8.3 3.9 1.9 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein GPI-anchored PF10342.4 EWM20012.1 - 0.0044 17.4 0.3 0.015 15.7 0.2 1.9 1 1 1 2 2 2 2 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family A2M_N PF01835.14 EWM20012.1 - 0.025 14.7 0.0 0.071 13.3 0.0 1.7 2 0 0 2 2 2 0 MG2 domain DUF3648 PF12364.3 EWM20013.1 - 0.047 13.6 0.1 0.07 13.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3648) ketoacyl-synt PF00109.21 EWM20016.1 - 5.4e-59 199.7 2.5 5.4e-59 199.7 1.7 1.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EWM20016.1 - 1.2e-23 83.2 0.6 2e-23 82.4 0.1 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain DUF3357 PF11837.3 EWM20017.1 - 0.12 12.2 0.1 18 5.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) PEP-utilisers_N PF05524.8 EWM20019.1 - 0.012 15.4 2.1 0.019 14.7 1.5 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Adenine_glyco PF03352.8 EWM20019.1 - 0.12 11.8 2.2 0.18 11.3 1.5 1.2 1 0 0 1 1 1 0 Methyladenine glycosylase vATP-synt_E PF01991.13 EWM20019.1 - 0.33 10.2 7.6 0.47 9.7 5.3 1.1 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit DUF1192 PF06698.6 EWM20019.1 - 6.5 6.6 8.4 11 5.9 2.4 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1192) Sds3 PF08598.6 EWM20020.1 - 0.015 14.8 4.2 0.023 14.2 2.9 1.3 1 0 0 1 1 1 0 Sds3-like RNaseH_C PF09293.5 EWM20020.1 - 0.28 11.0 2.5 5.7 6.8 1.8 2.3 1 1 0 1 1 1 0 T4 RNase H, C terminal Kri1 PF05178.7 EWM20020.1 - 0.91 9.8 6.8 1.3 9.3 4.7 1.2 1 0 0 1 1 1 0 KRI1-like family Robl_LC7 PF03259.12 EWM20022.1 - 0.0049 16.3 0.2 1.1 8.9 0.0 3.1 4 0 0 4 4 4 2 Roadblock/LC7 domain ABC_tran PF00005.22 EWM20024.1 - 6.3e-14 52.4 0.0 8.3e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 ABC transporter TPR_11 PF13414.1 EWM20028.1 - 4.5e-10 39.0 0.0 3.7e-07 29.6 0.0 1.9 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EWM20028.1 - 4.9e-06 26.0 0.0 0.025 14.4 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EWM20028.1 - 1.2e-05 25.5 0.0 1.6e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 EWM20028.1 - 7.7e-05 22.9 0.0 0.1 13.2 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EWM20028.1 - 8.1e-05 23.1 0.0 9.8e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 EWM20028.1 - 0.00015 21.6 0.0 0.0002 21.2 0.0 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 EWM20028.1 - 0.0018 18.2 0.0 1.9 8.8 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.5 EWM20028.1 - 0.0084 15.6 0.0 0.01 15.3 0.0 1.1 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_9 PF13371.1 EWM20028.1 - 0.027 14.3 0.1 0.036 13.9 0.1 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 EWM20028.1 - 0.055 13.0 0.0 0.99 9.1 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3808 PF10300.4 EWM20028.1 - 0.083 11.4 0.0 0.09 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) TPR_8 PF13181.1 EWM20028.1 - 0.15 11.9 0.0 13 5.8 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat Acyl_transf_1 PF00698.16 EWM20031.1 - 2.4e-48 165.1 0.1 2.8e-48 164.8 0.1 1.0 1 0 0 1 1 1 1 Acyl transferase domain UBN2_2 PF14227.1 EWM20038.1 - 0.0052 16.3 0.6 0.0089 15.5 0.4 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EWM20038.1 - 0.039 13.7 0.5 0.068 12.9 0.3 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type JmjN PF02375.12 EWM20038.1 - 0.052 13.0 0.0 7 6.2 0.0 2.5 2 0 0 2 2 2 0 jmjN domain Hint PF01079.15 EWM20038.1 - 0.096 11.8 0.0 0.25 10.5 0.0 1.6 2 0 0 2 2 2 0 Hint module zf-CCHC_5 PF14787.1 EWM20038.1 - 2.4 7.7 9.0 15 5.1 2.5 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger DUF21 PF01595.15 EWM20040.1 - 1.7e-11 43.7 0.4 3.3e-11 42.8 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF21 BAAT_C PF08840.6 EWM20041.1 - 0.017 14.8 0.1 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peripla_BP_2 PF01497.13 EWM20041.1 - 0.033 13.2 1.9 0.21 10.6 1.9 1.8 2 0 0 2 2 2 0 Periplasmic binding protein Phage_Mu_Gam PF07352.7 EWM20041.1 - 0.051 13.1 10.2 0.39 10.2 1.1 2.1 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein PEP-utilisers_N PF05524.8 EWM20041.1 - 0.089 12.5 8.9 0.17 11.7 6.1 1.5 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal MFS_1 PF07690.11 EWM20042.1 - 2.7e-07 29.6 7.8 2.8e-07 29.5 5.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily PUCC PF03209.10 EWM20042.1 - 0.12 11.1 2.3 0.12 11.0 1.6 1.1 1 0 0 1 1 1 0 PUCC protein Actin PF00022.14 EWM20044.1 - 2.6e-156 519.9 0.0 3e-156 519.7 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EWM20044.1 - 0.058 13.8 0.1 0.24 11.8 0.0 1.9 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) SBBP PF06739.6 EWM20045.1 - 0.0033 17.1 3.6 0.008 15.9 2.5 1.6 1 0 0 1 1 1 1 Beta-propeller repeat 4HB_MCP_1 PF12729.2 EWM20047.1 - 0.033 13.5 0.6 0.039 13.3 0.4 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction DUF1780 PF08682.5 EWM20047.1 - 0.083 12.3 0.0 0.083 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1780) TPR_12 PF13424.1 EWM20048.1 - 0.00045 20.1 0.9 0.14 12.0 0.0 3.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EWM20048.1 - 0.00089 18.8 3.7 0.0027 17.3 0.5 2.5 1 1 1 2 2 2 1 TPR repeat Apc3 PF12895.2 EWM20048.1 - 0.0013 18.8 3.8 0.011 15.7 0.0 3.0 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 EWM20048.1 - 0.0019 17.9 7.1 0.1 12.5 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EWM20048.1 - 0.002 17.6 1.1 0.039 13.5 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EWM20048.1 - 0.014 15.0 0.2 16 5.5 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EWM20048.1 - 0.024 14.4 0.0 0.076 12.8 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.1 EWM20048.1 - 0.027 14.3 0.1 0.027 14.3 0.1 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EWM20048.1 - 0.028 14.7 0.1 0.057 13.7 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 EWM20048.1 - 0.036 14.7 0.0 0.32 11.7 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EWM20048.1 - 0.1 12.8 0.9 0.4 11.0 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat ABC_tran PF00005.22 EWM20049.1 - 7.2e-07 29.5 0.0 1.1e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SbcCD_C PF13558.1 EWM20049.1 - 0.12 12.2 0.1 0.68 9.8 0.0 2.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Apolipoprotein PF01442.13 EWM20050.1 - 0.0004 19.9 2.0 0.0007 19.1 1.4 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Flagellin_C PF00700.16 EWM20050.1 - 0.11 12.7 3.8 6.6 6.9 0.8 3.6 1 1 2 3 3 3 0 Bacterial flagellin C-terminal helical region DUF2884 PF11101.3 EWM20050.1 - 0.18 11.1 2.6 0.25 10.6 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) CEP170_C PF15308.1 EWM20051.1 - 0.049 11.8 0.0 0.053 11.7 0.0 1.0 1 0 0 1 1 1 0 CEP170 C-terminus DUF2612 PF11041.3 EWM20051.1 - 0.08 12.5 0.0 0.095 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2612) UBN2_2 PF14227.1 EWM20053.1 - 2.7e-08 33.3 1.1 4.7e-08 32.6 0.8 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EWM20053.1 - 2.5e-06 27.2 0.3 4.2e-06 26.5 0.2 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF1759 PF03564.10 EWM20053.1 - 3e-05 23.8 0.8 0.00015 21.6 0.1 2.2 2 1 1 3 3 3 1 Protein of unknown function (DUF1759) zf-CCHC PF00098.18 EWM20053.1 - 0.016 15.1 4.7 0.016 15.1 3.2 2.2 2 0 0 2 2 2 0 Zinc knuckle eIF3g PF12353.3 EWM20053.1 - 0.038 13.8 1.5 0.06 13.2 0.4 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G PP-binding PF00550.20 EWM20053.1 - 0.062 13.5 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphopantetheine attachment site PEP-utilisers_N PF05524.8 EWM20054.1 - 0.0012 18.6 3.4 0.0019 18.0 2.3 1.4 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal DUF1789 PF08748.6 EWM20054.1 - 0.24 11.4 5.2 0.34 10.9 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1789) Phage_Mu_Gam PF07352.7 EWM20054.1 - 0.48 9.9 6.6 0.66 9.4 3.8 1.7 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein vATP-synt_E PF01991.13 EWM20054.1 - 0.86 8.8 11.0 1.2 8.3 7.6 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit DUF1843 PF08898.5 EWM20054.1 - 8.2 6.5 12.1 11 6.1 1.3 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF1843) Trp_oprn_chp PF09534.5 EWM20057.1 - 0.0055 16.3 1.5 0.0073 15.9 1.0 1.4 1 1 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) FixH PF05751.6 EWM20057.1 - 0.039 13.7 0.7 0.054 13.3 0.5 1.2 1 0 0 1 1 1 0 FixH Phage_Mu_Gam PF07352.7 EWM20060.1 - 0.076 12.5 9.3 0.21 11.0 1.9 2.1 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein BAAT_C PF08840.6 EWM20060.1 - 0.098 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal UBA_4 PF14555.1 EWM20062.1 - 0.027 13.9 0.2 0.36 10.4 0.1 2.1 1 1 1 2 2 2 0 UBA-like domain NeA_P2 PF12312.3 EWM20065.1 - 0.22 10.7 1.8 0.25 10.5 1.2 1.1 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein Mito_fiss_reg PF05308.6 EWM20065.1 - 1.1 8.6 3.6 1.1 8.5 2.5 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 EWM20065.1 - 4.9 6.3 6.1 6.1 6.0 4.2 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PEP-utilisers_N PF05524.8 EWM20066.1 - 0.012 15.4 0.7 0.018 14.7 0.5 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Rsm22 PF09243.5 EWM20067.1 - 0.041 12.9 0.3 0.047 12.7 0.2 1.0 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Collagen PF01391.13 EWM20068.1 - 3.1e-09 36.2 22.0 4.3e-09 35.7 15.2 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) DAP10 PF07213.6 EWM20068.1 - 0.074 12.8 0.1 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 DAP10 membrane protein Nodulin PF02451.10 EWM20068.1 - 0.15 11.4 0.1 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 Nodulin SSP160 PF06933.6 EWM20068.1 - 1.3 6.8 7.7 1.5 6.6 5.3 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 RVT_2 PF07727.9 EWM20071.1 - 4.8e-85 284.4 0.0 6.1e-85 284.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PhyH PF05721.8 EWM20072.1 - 3e-10 40.4 0.1 4.3e-10 39.9 0.1 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Hydrolase_like2 PF13246.1 EWM20076.1 - 2.6e-09 36.9 0.0 4.2e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit DUF2073 PF09846.4 EWM20076.1 - 0.13 11.9 0.1 0.26 10.9 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2073) PQQ_3 PF13570.1 EWM20077.1 - 0.19 12.0 6.7 0.92 9.8 0.1 3.1 3 1 0 3 3 3 0 PQQ-like domain LVIVD PF08309.6 EWM20077.1 - 0.64 9.0 17.4 0.17 10.9 0.3 3.5 4 0 0 4 4 4 0 LVIVD repeat FBPase PF00316.15 EWM20080.1 - 6.6e-17 61.3 0.2 7.7e-17 61.1 0.1 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Myb_DNA-binding PF00249.26 EWM20081.1 - 4.7e-11 42.5 1.2 7.9e-11 41.8 0.8 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF4407 PF14362.1 EWM20082.1 - 0.004 16.1 9.9 0.0055 15.7 6.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) PEP-utilisers_N PF05524.8 EWM20082.1 - 0.0061 16.3 11.9 0.0089 15.8 8.3 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal BAAT_C PF08840.6 EWM20082.1 - 0.036 13.7 0.1 0.05 13.3 0.1 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF4618 PF15397.1 EWM20082.1 - 0.038 13.3 2.2 0.045 13.0 1.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) Phage_Mu_Gam PF07352.7 EWM20082.1 - 0.056 12.9 14.4 0.11 12.0 3.7 2.2 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein TMPIT PF07851.8 EWM20082.1 - 0.14 11.1 0.7 0.24 10.4 0.5 1.3 1 0 0 1 1 1 0 TMPIT-like protein ATP-synt_B PF00430.13 EWM20082.1 - 0.85 9.4 16.8 1.4 8.7 11.7 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Bap31 PF05529.7 EWM20082.1 - 1.3 8.4 4.0 2.7 7.4 2.8 1.5 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF4140 PF13600.1 EWM20082.1 - 2.1 8.8 10.9 15 6.1 7.6 2.1 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF1192 PF06698.6 EWM20082.1 - 4.9 7.0 17.5 8 6.3 1.1 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF1192) DUF1843 PF08898.5 EWM20082.1 - 9.6 6.3 18.5 6.8 6.8 1.4 3.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1843) Lipase_3 PF01764.20 EWM20084.1 - 2.9e-05 23.7 0.0 3.4e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) ABC2_membrane_3 PF12698.2 EWM20089.1 - 0.14 11.2 4.7 0.18 10.8 3.3 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein rve PF00665.21 EWM20093.1 - 1.9e-20 73.1 0.0 3.2e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain PCYCGC PF13798.1 EWM20094.1 - 0.26 10.9 0.9 0.44 10.2 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function with PCYCGC motif ketoacyl-synt PF00109.21 EWM20096.1 - 1.4e-87 293.4 2.7 2.3e-87 292.6 1.9 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EWM20096.1 - 3.6e-23 81.6 0.1 7e-23 80.7 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EWM20096.1 - 1.1e-09 38.3 0.1 2.1e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EWM20096.1 - 0.00075 18.5 0.3 0.0014 17.6 0.2 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EWM20096.1 - 0.067 12.8 2.1 0.11 12.2 0.1 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FAE1_CUT1_RppA PF08392.7 EWM20096.1 - 0.11 11.5 0.1 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 FAE1/Type III polyketide synthase-like protein LCE PF14672.1 EWM20098.1 - 4.4 7.8 9.9 1.1 9.8 4.0 2.0 2 0 0 2 2 2 0 Late cornified envelope Urm1 PF09138.6 EWM20099.1 - 1.9e-06 27.9 0.2 2.1 8.5 0.0 4.2 2 1 2 4 4 4 2 Urm1 (Ubiquitin related modifier) OapA PF04225.7 EWM20099.1 - 1.3e-05 25.0 0.0 1.7 8.5 0.0 4.3 5 0 0 5 5 5 3 Opacity-associated protein A LysM-like domain LVIVD PF08309.6 EWM20099.1 - 0.0013 17.6 7.4 11 5.0 0.1 4.5 4 0 0 4 4 4 4 LVIVD repeat Glyco_hydro_12 PF01670.11 EWM20099.1 - 0.072 12.8 0.1 2.1 8.0 0.0 2.2 1 1 1 2 2 2 0 Glycosyl hydrolase family 12 DUF667 PF05018.8 EWM20102.1 - 2.6e-31 108.3 0.0 3.1e-31 108.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Peptidase_M8 PF01457.11 EWM20104.1 - 6.6e-06 24.7 0.0 8.9e-06 24.3 0.0 1.1 1 0 0 1 1 1 1 Leishmanolysin SprT-like PF10263.4 EWM20104.1 - 0.0024 17.5 0.0 0.0037 16.9 0.0 1.3 1 0 0 1 1 1 1 SprT-like family HTH_15 PF12324.3 EWM20104.1 - 0.11 12.2 0.1 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase Phage_Mu_Gam PF07352.7 EWM20106.1 - 0.066 12.7 3.0 0.096 12.2 1.9 1.3 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein Holin_LLH PF09682.5 EWM20106.1 - 0.11 12.6 1.9 0.15 12.1 1.3 1.2 1 0 0 1 1 1 0 Phage holin protein (Holin_LLH) Sulfotransfer_2 PF03567.9 EWM20106.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Sulfotransferase family PT PF04886.7 EWM20109.1 - 0.0021 17.3 76.3 34 3.8 5.5 3.5 2 1 0 2 2 2 1 PT repeat DUF4366 PF14283.1 EWM20112.1 - 0.07 12.5 0.2 0.082 12.3 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) K_channel_TID PF07941.6 EWM20112.1 - 0.12 12.5 10.2 0.24 11.6 2.7 2.1 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain ABC_tran PF00005.22 EWM20116.1 - 8.7e-10 39.0 0.0 1.2e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EWM20116.1 - 3.7e-06 27.1 0.0 5.1e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 EWM20116.1 - 0.015 15.1 0.2 0.21 11.5 0.2 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.4 EWM20116.1 - 0.02 13.4 0.1 0.32 9.5 0.0 2.0 1 1 0 1 1 1 0 Predicted ATPase of the ABC class Xan_ur_permease PF00860.15 EWM20117.1 - 5.7e-05 21.7 0.2 6.8e-05 21.5 0.2 1.0 1 0 0 1 1 1 1 Permease family PEP-utilisers_N PF05524.8 EWM20119.1 - 0.0015 18.2 8.4 0.0024 17.6 5.8 1.3 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal Spc7 PF08317.6 EWM20119.1 - 0.0032 16.1 5.4 0.0043 15.7 3.8 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein BAAT_C PF08840.6 EWM20119.1 - 0.027 14.1 0.2 0.04 13.6 0.1 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Phage_Mu_Gam PF07352.7 EWM20119.1 - 0.21 11.0 13.6 0.31 10.5 5.8 2.3 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein TMPIT PF07851.8 EWM20119.1 - 0.45 9.5 4.7 0.071 12.1 0.6 1.4 2 0 0 2 2 2 0 TMPIT-like protein DUF4140 PF13600.1 EWM20119.1 - 0.62 10.5 13.6 2.6 8.5 2.6 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Atg14 PF10186.4 EWM20119.1 - 0.63 8.9 2.7 0.86 8.4 1.9 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 EWM20119.1 - 4.8 6.7 12.0 12 5.4 2.9 2.4 1 1 1 2 2 2 0 Septum formation initiator PAT1 PF09770.4 EWM20120.1 - 4.2 5.4 8.8 5.2 5.1 6.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-like PF04071.7 EWM20121.1 - 0.3 10.7 1.5 2.6 7.8 0.1 2.7 3 0 0 3 3 3 0 Cysteine-rich small domain Ank PF00023.25 EWM20122.1 - 1.1e-05 24.9 1.4 0.015 15.1 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EWM20122.1 - 0.00014 22.1 0.0 0.00085 19.6 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EWM20122.1 - 0.0059 16.7 0.4 1.3 9.5 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 EWM20122.1 - 0.03 14.5 0.4 16 5.9 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeats (many copies) rve PF00665.21 EWM20124.1 - 1.7e-22 79.7 0.0 2.6e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EWM20124.1 - 1.4e-08 34.2 0.0 2.9e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 EWM20124.1 - 0.0074 15.7 0.0 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Val_tRNA-synt_C PF10458.4 EWM20131.1 - 4.8e-15 55.3 3.1 8.7e-15 54.5 2.2 1.4 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm Mnd1 PF03962.10 EWM20131.1 - 0.14 11.7 0.2 0.17 11.5 0.2 1.2 1 1 0 1 1 1 0 Mnd1 family Bacillus_HBL PF05791.6 EWM20131.1 - 0.15 11.4 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) gag_pre-integrs PF13976.1 EWM20134.1 - 5.8e-07 29.0 0.0 1.5e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain eIF3g PF12353.3 EWM20134.1 - 0.016 15.0 0.7 0.05 13.5 0.5 1.8 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC PF00098.18 EWM20134.1 - 0.028 14.3 3.3 0.028 14.3 2.3 3.1 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_4 PF14392.1 EWM20134.1 - 0.32 10.6 8.8 3 7.5 0.4 3.1 3 0 0 3 3 3 0 Zinc knuckle YuzL PF14115.1 EWM20137.1 - 5.8 7.2 7.4 1.7 9.0 0.5 2.8 3 0 0 3 3 3 0 YuzL-like protein UBA_e1_C PF09358.5 EWM20138.1 - 1.1e-37 128.9 0.0 1.4e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain Aa_trans PF01490.13 EWM20142.1 - 1.7e-21 76.2 10.1 1.9e-21 76.0 7.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PT PF04886.7 EWM20143.1 - 3.8e-07 29.2 143.5 0.014 14.7 20.5 6.6 2 1 4 6 6 6 5 PT repeat PEP-utilisers_N PF05524.8 EWM20145.1 - 0.017 14.9 0.9 0.026 14.3 0.7 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Phage_Mu_Gam PF07352.7 EWM20145.1 - 0.038 13.5 3.6 0.053 13.0 2.5 1.3 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein DUF1192 PF06698.6 EWM20145.1 - 4.8 7.0 7.4 6.5 6.6 0.6 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) Phage_Mu_Gam PF07352.7 EWM20146.1 - 0.027 13.9 4.1 0.038 13.5 2.8 1.3 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein PEP-utilisers_N PF05524.8 EWM20146.1 - 0.06 13.1 3.6 0.091 12.5 2.5 1.4 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal BAAT_C PF08840.6 EWM20146.1 - 0.076 12.7 0.0 0.092 12.4 0.0 1.1 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1843 PF08898.5 EWM20146.1 - 1.8 8.6 6.2 5.1 7.2 1.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1843) DUF1192 PF06698.6 EWM20146.1 - 2.5 7.9 7.8 4.4 7.1 0.6 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) WEMBL PF05701.6 EWM20148.1 - 0.0062 15.0 5.6 0.0078 14.7 3.9 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light OEP PF02321.13 EWM20148.1 - 0.57 9.7 4.1 0.79 9.2 2.8 1.2 1 0 0 1 1 1 0 Outer membrane efflux protein P22_Cro PF14549.1 EWM20149.1 - 0.038 13.7 0.0 0.064 12.9 0.0 1.4 1 1 0 1 1 1 0 DNA-binding transcriptional regulator Cro PT PF04886.7 EWM20154.1 - 0.00018 20.7 16.1 0.00018 20.7 11.2 4.0 2 1 0 2 2 2 1 PT repeat DUF4394 PF14339.1 EWM20154.1 - 0.095 11.9 0.9 1.4 8.1 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4394) WW PF00397.21 EWM20154.1 - 3.1 7.7 7.4 16 5.5 0.1 3.3 3 0 0 3 3 3 0 WW domain RVT_2 PF07727.9 EWM20156.1 - 1.7e-46 158.2 0.0 3.3e-46 157.2 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EWM20156.1 - 1.1e-22 80.4 0.0 1.8e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EWM20156.1 - 4.2e-08 32.7 0.0 8.6e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 EWM20156.1 - 0.077 12.5 0.0 0.2 11.1 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain PyrI_C PF02748.10 EWM20157.1 - 0.012 15.0 1.7 0.23 10.9 0.1 2.1 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Nucleotid_trans PF03407.11 EWM20159.1 - 2.4e-06 27.5 0.0 3.3e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase ADH_zinc_N PF00107.21 EWM20163.1 - 2.1e-17 62.9 0.0 3.6e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PS-DH PF14765.1 EWM20163.1 - 6.3e-13 48.5 0.1 1.7e-12 47.0 0.0 1.8 3 0 0 3 3 3 1 Polyketide synthase dehydratase ADH_N PF08240.7 EWM20163.1 - 1.2e-08 34.6 0.4 3.2e-08 33.3 0.3 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EWM20163.1 - 0.00055 19.5 0.1 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain BAAT_C PF08840.6 EWM20166.1 - 0.016 14.9 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peripla_BP_2 PF01497.13 EWM20166.1 - 0.078 12.0 3.2 0.65 9.0 3.2 1.8 2 1 0 2 2 2 0 Periplasmic binding protein PEP-utilisers_N PF05524.8 EWM20166.1 - 0.29 10.9 9.4 0.73 9.6 6.5 1.7 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal Glyco_transf_64 PF09258.5 EWM20167.1 - 1.6e-27 96.2 0.0 2.5e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Methyltransf_23 PF13489.1 EWM20167.1 - 1.6e-08 34.4 0.1 5.9e-08 32.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.1 EWM20167.1 - 2.5e-08 34.6 0.1 1.3e-05 25.9 0.0 2.7 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EWM20167.1 - 0.00011 22.6 0.0 0.00043 20.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM20167.1 - 0.00029 21.2 0.0 0.0034 17.8 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM20167.1 - 0.00082 19.9 0.0 0.9 10.1 0.0 2.9 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.1 EWM20167.1 - 0.0097 15.4 0.0 0.025 14.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain RVT_2 PF07727.9 EWM20168.1 - 3.7e-37 127.6 0.0 7.8e-37 126.5 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EWM20168.1 - 5e-22 78.2 0.0 8.3e-22 77.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EWM20168.1 - 1.6e-08 34.0 0.0 3.1e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 EWM20168.1 - 0.017 14.6 0.0 0.038 13.5 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Glycos_transf_2 PF00535.21 EWM20169.1 - 1.4e-09 37.8 0.0 1.8e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.1 EWM20169.1 - 0.00014 22.0 0.0 0.0002 21.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EWM20169.1 - 0.0066 16.2 0.1 0.012 15.3 0.0 1.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 RRM_6 PF14259.1 EWM20172.1 - 4.8e-07 29.6 0.0 8.6e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EWM20172.1 - 0.00045 19.7 0.0 0.00087 18.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PIRT PF15099.1 EWM20173.1 - 0.44 9.7 3.5 0.57 9.3 2.4 1.2 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family DUF2909 PF11137.3 EWM20173.1 - 1.1 9.0 5.6 15 5.4 0.3 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF2909) Autophagy_N PF03986.8 EWM20178.1 - 0.053 13.2 2.9 0.062 13.0 2.0 1.1 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain TolA PF06519.6 EWM20180.1 - 0.066 13.1 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 TolA C-terminal Trigger_N PF05697.8 EWM20183.1 - 0.041 13.6 0.0 0.06 13.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) BK_channel_a PF03493.13 EWM20186.1 - 0.028 14.3 0.6 4.3 7.3 0.0 2.6 2 0 0 2 2 2 0 Calcium-activated BK potassium channel alpha subunit UPF0118 PF01594.11 EWM20186.1 - 0.087 11.8 0.8 4.3 6.2 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF20 VirB3 PF05101.8 EWM20186.1 - 0.089 12.7 0.2 11 6.0 0.0 2.3 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein RVT_2 PF07727.9 EWM20187.1 - 3.1e-71 239.2 0.0 6.9e-69 231.5 0.0 2.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EWM20187.1 - 9.8e-13 48.2 0.0 3.1e-12 46.6 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain fn3 PF00041.16 EWM20188.1 - 1.8e-19 69.6 4.9 6.9e-09 35.7 0.3 2.7 3 0 0 3 3 3 2 Fibronectin type III domain DUF1494 PF07379.6 EWM20191.1 - 0.074 12.9 0.0 1.9 8.3 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1494) DUF1494 PF07379.6 EWM20192.1 - 0.074 12.9 0.0 1.9 8.3 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1494) DUF1494 PF07379.6 EWM20193.1 - 0.074 12.9 0.0 1.9 8.3 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1494) Glyco_transf_64 PF09258.5 EWM20194.1 - 1.3e-20 73.6 0.0 1.8e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain DUF563 PF04577.9 EWM20196.1 - 7.5e-24 84.7 0.0 1.3e-23 83.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DUF563 PF04577.9 EWM20197.1 - 7.3e-24 84.8 0.0 1.3e-23 84.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) UBN2 PF14223.1 EWM20198.1 - 0.011 15.5 0.2 0.011 15.5 0.1 1.0 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EWM20198.1 - 0.046 13.2 0.2 0.047 13.2 0.1 1.0 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type RVT_2 PF07727.9 EWM20200.1 - 2e-84 282.3 0.0 3.1e-84 281.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PNTB PF02233.11 EWM20202.1 - 0.01 14.6 0.1 0.013 14.2 0.1 1.1 1 0 0 1 1 1 0 NAD(P) transhydrogenase beta subunit ACT_3 PF10000.4 EWM20202.1 - 0.13 12.0 0.1 0.72 9.6 0.0 2.2 2 0 0 2 2 2 0 ACT domain DUF1494 PF07379.6 EWM20203.1 - 0.054 13.4 0.0 0.21 11.4 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1494) MFS_1 PF07690.11 EWM20208.1 - 1.6e-26 92.8 22.1 2.3e-26 92.3 15.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EWM20208.1 - 6.7e-07 28.2 16.9 1e-05 24.3 11.7 2.2 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EWM20208.1 - 2e-06 26.4 2.5 2e-06 26.4 1.8 1.9 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.2 EWM20208.1 - 9.1e-06 25.3 1.7 0.00012 21.7 1.3 2.1 2 0 0 2 2 2 1 MFS_1 like family OATP PF03137.15 EWM20208.1 - 0.044 11.8 6.2 0.013 13.5 1.1 1.9 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF981 PF06168.6 EWM20208.1 - 0.049 13.4 3.7 0.078 12.7 2.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF981) LacY_symp PF01306.14 EWM20208.1 - 0.16 10.4 8.3 0.21 10.1 5.7 1.1 1 0 0 1 1 1 0 LacY proton/sugar symporter Glycos_transf_2 PF00535.21 EWM20210.1 - 0.00069 19.3 0.1 0.0016 18.1 0.1 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 2 FAD_binding_4 PF01565.18 EWM20212.1 - 1.4e-24 86.1 2.3 3.5e-24 84.8 1.6 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EWM20212.1 - 4.2e-06 26.5 0.4 1e-05 25.3 0.3 1.7 1 0 0 1 1 1 1 Berberine and berberine like AvrPtoB-E3_ubiq PF09046.5 EWM20215.1 - 0.0026 17.7 0.0 0.0034 17.3 0.0 1.2 1 0 0 1 1 1 1 AvrPtoB E3 ubiquitin ligase RVT_2 PF07727.9 EWM20216.1 - 1.3e-27 96.3 0.0 1.5e-27 96.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EGF_2 PF07974.8 EWM20217.1 - 0.019 15.0 1.2 0.019 15.0 0.8 2.0 3 0 0 3 3 3 0 EGF-like domain RVT_2 PF07727.9 EWM20220.1 - 3.8e-11 42.4 0.0 4.9e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MGAT2 PF05060.9 EWM20221.1 - 0.02 13.8 0.1 0.029 13.2 0.1 1.3 1 0 0 1 1 1 0 N-acetylglucosaminyltransferase II (MGAT2) MOZART1 PF12554.3 EWM20222.1 - 0.057 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated Phage_Mu_Gam PF07352.7 EWM20226.1 - 0.049 13.1 6.2 0.042 13.3 2.5 2.2 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein DUF4618 PF15397.1 EWM20226.1 - 0.098 11.9 3.1 0.13 11.5 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DUF1690 PF07956.6 EWM20226.1 - 0.23 11.4 3.2 0.32 10.9 2.2 1.2 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) CAF-1_p150 PF11600.3 EWM20226.1 - 0.61 9.4 8.1 0.84 8.9 5.6 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Glyoxalase_2 PF12681.2 EWM20227.1 - 1.3e-13 51.4 0.1 1.9e-08 34.8 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase PF00903.20 EWM20227.1 - 1.7e-09 37.7 0.0 6.8e-08 32.5 0.0 2.2 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF3081 PF11280.3 EWM20227.1 - 0.00054 19.4 0.3 0.1 12.0 0.0 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF3081) DUF2959 PF11172.3 EWM20230.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) Syntaxin PF00804.20 EWM20230.1 - 0.13 12.4 0.1 0.19 11.8 0.1 1.3 1 1 0 1 1 1 0 Syntaxin Baculo_PEP_C PF04513.7 EWM20230.1 - 0.16 11.8 0.0 0.22 11.3 0.0 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus UBN2_2 PF14227.1 EWM20232.1 - 7.2e-08 32.0 0.6 1.7e-07 30.8 0.4 1.7 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EWM20232.1 - 0.00021 21.0 0.1 0.00039 20.1 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF1759 PF03564.10 EWM20232.1 - 0.00041 20.1 1.3 0.0016 18.2 0.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) zf-CCHC_4 PF14392.1 EWM20232.1 - 0.45 10.2 3.3 0.46 10.2 0.4 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.18 EWM20232.1 - 4.7 7.3 18.4 0.16 11.9 1.2 2.8 3 0 0 3 3 3 0 Zinc knuckle DUF2019 PF09450.5 EWM20233.1 - 0.0039 17.0 0.0 0.005 16.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2019) DUF4319 PF14203.1 EWM20233.1 - 0.0056 16.1 0.1 0.014 14.9 0.1 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4319) TBPIP PF07106.8 EWM20233.1 - 0.0065 16.0 0.7 0.0083 15.6 0.5 1.2 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fib_alpha PF08702.5 EWM20233.1 - 0.012 15.7 0.5 0.015 15.4 0.3 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family EzrA PF06160.7 EWM20233.1 - 0.019 13.1 0.6 0.022 12.9 0.4 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF4164 PF13747.1 EWM20233.1 - 0.047 13.8 0.3 0.44 10.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) MTD PF01993.13 EWM20233.1 - 0.091 11.7 0.3 0.12 11.3 0.2 1.1 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase RVT_2 PF07727.9 EWM20234.1 - 1.1e-56 191.5 0.0 1.6e-56 191.0 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNA_pol_I_A49 PF06870.7 EWM20234.1 - 0.086 11.3 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 A49-like RNA polymerase I associated factor ATP_synt_H PF05493.8 EWM20235.1 - 0.14 12.2 3.0 0.24 11.5 2.1 1.7 1 1 0 1 1 1 0 ATP synthase subunit H Epimerase PF01370.16 EWM20236.1 - 1.4e-33 116.3 0.0 1.9e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Exostosin PF03016.10 EWM20236.1 - 2.4e-30 105.6 0.0 4.4e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 Exostosin family 3Beta_HSD PF01073.14 EWM20236.1 - 1.1e-14 53.8 0.0 1.7e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EWM20236.1 - 1.2e-14 53.9 0.0 2e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EWM20236.1 - 1.2e-10 40.7 0.0 2e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EWM20236.1 - 5.7e-09 35.2 0.0 7.6e-08 31.6 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EWM20236.1 - 1.8e-08 34.5 0.0 2.9e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EWM20236.1 - 2.6e-07 30.5 0.0 4e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EWM20236.1 - 0.0035 16.6 0.0 0.0067 15.7 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family 2-Hacid_dh_C PF02826.14 EWM20236.1 - 0.26 10.4 0.0 0.43 9.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 EWM20236.1 - 0.27 11.2 0.1 0.53 10.2 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Epimerase PF01370.16 EWM20237.1 - 1.4e-33 116.3 0.0 1.9e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Exostosin PF03016.10 EWM20237.1 - 2.4e-30 105.6 0.0 4.4e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 Exostosin family 3Beta_HSD PF01073.14 EWM20237.1 - 1.1e-14 53.8 0.0 1.7e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EWM20237.1 - 1.2e-14 53.9 0.0 2e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EWM20237.1 - 1.2e-10 40.7 0.0 2e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EWM20237.1 - 5.7e-09 35.2 0.0 7.6e-08 31.6 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EWM20237.1 - 1.8e-08 34.5 0.0 2.9e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EWM20237.1 - 2.6e-07 30.5 0.0 4e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EWM20237.1 - 0.0035 16.6 0.0 0.0067 15.7 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family 2-Hacid_dh_C PF02826.14 EWM20237.1 - 0.26 10.4 0.0 0.43 9.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 EWM20237.1 - 0.27 11.2 0.1 0.53 10.2 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain MOZART1 PF12554.3 EWM20239.1 - 0.073 12.5 0.1 0.19 11.2 0.0 1.6 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated MOZART1 PF12554.3 EWM20240.1 - 0.063 12.7 0.1 0.31 10.5 0.0 2.0 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated Epimerase PF01370.16 EWM20243.1 - 5e-34 117.7 0.0 7.2e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Exostosin PF03016.10 EWM20243.1 - 3.5e-31 108.3 0.0 7e-31 107.3 0.0 1.5 1 1 0 1 1 1 1 Exostosin family 3Beta_HSD PF01073.14 EWM20243.1 - 3.9e-15 55.3 0.0 5.9e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EWM20243.1 - 5.4e-15 55.0 0.0 9.4e-15 54.2 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EWM20243.1 - 4.8e-10 38.7 0.0 8.3e-10 37.9 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EWM20243.1 - 2.4e-09 36.5 0.0 3.1e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EWM20243.1 - 6.4e-09 35.9 0.0 1e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EWM20243.1 - 1.3e-07 31.4 0.0 2.1e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EWM20243.1 - 0.005 16.1 0.0 0.0094 15.2 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 EWM20243.1 - 0.22 11.5 0.1 0.46 10.5 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_10 PF13460.1 EWM20243.1 - 0.32 10.9 0.1 0.61 10.0 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 EWM20244.1 - 5e-34 117.7 0.0 7.2e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Exostosin PF03016.10 EWM20244.1 - 3.5e-31 108.3 0.0 7e-31 107.3 0.0 1.5 1 1 0 1 1 1 1 Exostosin family 3Beta_HSD PF01073.14 EWM20244.1 - 3.9e-15 55.3 0.0 5.9e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EWM20244.1 - 5.4e-15 55.0 0.0 9.4e-15 54.2 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EWM20244.1 - 4.8e-10 38.7 0.0 8.3e-10 37.9 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EWM20244.1 - 2.4e-09 36.5 0.0 3.1e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EWM20244.1 - 6.4e-09 35.9 0.0 1e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EWM20244.1 - 1.3e-07 31.4 0.0 2.1e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EWM20244.1 - 0.005 16.1 0.0 0.0094 15.2 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 EWM20244.1 - 0.22 11.5 0.1 0.46 10.5 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_10 PF13460.1 EWM20244.1 - 0.32 10.9 0.1 0.61 10.0 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding Glycos_transf_2 PF00535.21 EWM20245.1 - 1.1e-09 38.1 0.0 1.5e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.1 EWM20245.1 - 9.3e-05 22.6 0.0 0.00013 22.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EWM20245.1 - 0.0083 15.9 0.1 0.016 15.0 0.0 1.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 PT PF04886.7 EWM20247.1 - 6.3e-11 41.3 65.9 69 2.8 35.6 4.2 2 1 0 2 2 2 0 PT repeat BNR PF02012.15 EWM20247.1 - 0.11 12.3 0.2 0.11 12.3 0.1 3.3 4 0 0 4 4 4 0 BNR/Asp-box repeat Alpha_adaptinC2 PF02883.15 EWM20247.1 - 0.13 12.5 0.0 0.13 12.5 0.0 2.4 2 1 0 2 2 2 0 Adaptin C-terminal domain DUF4106 PF13388.1 EWM20247.1 - 0.15 10.9 10.3 0.35 9.7 7.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) PAT1 PF09770.4 EWM20247.1 - 1.1 7.3 8.7 1.4 7.0 6.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 OB_RNB PF08206.6 EWM20249.1 - 0.0028 17.1 0.0 0.011 15.1 0.0 2.0 2 0 0 2 2 2 1 Ribonuclease B OB domain WW PF00397.21 EWM20250.1 - 1.5e-13 50.3 4.3 1.1e-06 28.3 1.2 3.1 2 0 0 2 2 2 2 WW domain SUN PF03856.8 EWM20251.1 - 8.8e-10 38.2 7.1 0.00033 20.0 0.1 2.6 2 0 0 2 2 2 2 Beta-glucosidase (SUN family) G8 PF10162.4 EWM20251.1 - 0.0021 17.8 0.1 0.0085 15.8 0.0 2.0 2 0 0 2 2 2 1 G8 domain Beta_helix PF13229.1 EWM20252.1 - 0.0034 17.1 1.2 0.023 14.4 0.9 2.1 1 1 0 1 1 1 1 Right handed beta helix region Chlam_PMP PF02415.12 EWM20252.1 - 0.06 13.6 0.6 0.06 13.6 0.4 6.1 7 0 0 7 7 7 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Abhydrolase_5 PF12695.2 EWM20252.1 - 0.096 12.4 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family RVT_2 PF07727.9 EWM20259.1 - 2e-09 36.8 0.1 2.8e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EWM20259.1 - 0.02 14.9 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain RVT_2 PF07727.9 EWM20261.1 - 6.5e-50 169.3 0.0 1.3e-47 161.8 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4376 PF14301.1 EWM20262.1 - 0.065 13.3 0.1 0.13 12.4 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4376) DUF4376 PF14301.1 EWM20263.1 - 0.065 13.3 0.1 0.13 12.4 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4376) UBN2_2 PF14227.1 EWM20264.1 - 4.7e-09 35.8 1.2 7.1e-09 35.2 0.9 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EWM20264.1 - 1.6e-06 27.8 0.3 2.8e-06 27.1 0.2 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF1759 PF03564.10 EWM20264.1 - 8.1e-06 25.7 0.7 3.2e-05 23.7 0.1 2.1 2 1 1 3 3 3 1 Protein of unknown function (DUF1759) zf-CCHC_4 PF14392.1 EWM20264.1 - 0.055 13.1 1.1 0.28 10.8 0.4 2.2 2 0 0 2 2 2 0 Zinc knuckle DUF288 PF03385.12 EWM20265.1 - 4.8e-15 54.9 0.0 7.1e-15 54.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF288 Glyco_tranf_2_4 PF13704.1 EWM20265.1 - 2e-07 31.2 0.1 8.2e-07 29.2 0.0 2.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cullin PF00888.17 EWM20265.1 - 0.16 10.4 0.0 0.24 9.9 0.0 1.1 1 0 0 1 1 1 0 Cullin family UBN2_2 PF14227.1 EWM20266.1 - 3.1e-05 23.4 1.5 4.2e-05 23.1 1.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EWM20266.1 - 0.00044 20.0 0.8 0.00067 19.4 0.5 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.1 EWM20266.1 - 0.047 13.3 0.4 0.093 12.4 0.3 1.6 1 0 0 1 1 1 0 Zinc knuckle UBA_e1_C PF09358.5 EWM20266.1 - 0.085 13.0 0.1 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-activating enzyme e1 C-terminal domain PP-binding PF00550.20 EWM20266.1 - 0.11 12.7 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphopantetheine attachment site JmjN PF02375.12 EWM20266.1 - 0.16 11.5 0.0 13 5.4 0.0 2.5 2 0 0 2 2 2 0 jmjN domain RVT_2 PF07727.9 EWM20268.1 - 0.0047 15.9 0.0 0.0065 15.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sulfotransfer_2 PF03567.9 EWM20269.1 - 3e-10 40.2 0.1 3.5e-08 33.4 0.0 2.1 2 0 0 2 2 2 2 Sulfotransferase family TIP49 PF06068.8 EWM20278.1 - 5.6e-12 45.0 0.1 1.7e-11 43.4 0.0 1.7 1 1 1 2 2 2 1 TIP49 C-terminus GST_N PF02798.15 EWM20279.1 - 5.2e-05 23.3 0.0 0.00012 22.2 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EWM20279.1 - 0.0024 18.0 0.0 0.004 17.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain CTP_synth_N PF06418.9 EWM20281.1 - 7.6e-16 58.0 0.6 9.7e-16 57.6 0.4 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EWM20284.1 - 6.6e-31 107.2 0.1 6.9e-30 103.9 0.0 2.4 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EWM20284.1 - 0.00094 18.6 0.1 0.12 11.7 0.0 2.2 2 0 0 2 2 2 2 Peptidase C26 adh_short PF00106.20 EWM20288.1 - 2.3e-06 27.6 0.5 2.8e-06 27.3 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EWM20288.1 - 0.00057 19.9 0.2 0.0007 19.6 0.1 1.1 1 0 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EWM20288.1 - 0.0063 16.2 0.1 0.0078 15.9 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2-Hacid_dh_C PF02826.14 EWM20288.1 - 0.016 14.3 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DFP PF04127.10 EWM20288.1 - 0.08 12.5 0.1 0.098 12.2 0.1 1.1 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein SpoU_methylase PF00588.14 EWM20290.1 - 5.7e-11 42.4 0.0 1.6e-10 41.0 0.0 1.6 1 1 0 1 1 1 1 SpoU rRNA Methylase family Ribonuclease_T2 PF00445.13 EWM20292.1 - 0.0047 16.5 0.0 0.0097 15.5 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease T2 family Meth_synt_2 PF01717.13 EWM20293.1 - 1e-80 271.1 0.0 2.4e-79 266.6 0.0 2.3 2 0 0 2 2 2 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EWM20293.1 - 2.8e-69 233.7 0.0 1.8e-63 214.6 0.0 2.7 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain Aldo_ket_red PF00248.16 EWM20294.1 - 6e-13 48.2 0.0 6.8e-13 48.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ion_trans_2 PF07885.11 EWM20296.1 - 2.2e-25 88.1 22.6 6.7e-14 51.3 6.2 2.3 2 0 0 2 2 2 2 Ion channel EF-hand_7 PF13499.1 EWM20296.1 - 2.5e-05 24.3 0.6 2.5e-05 24.3 0.4 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EWM20296.1 - 4.3e-05 22.5 0.2 0.36 10.2 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EWM20296.1 - 0.00011 21.7 0.1 0.25 11.3 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EWM20296.1 - 0.00028 20.4 0.0 0.62 9.7 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EWM20296.1 - 0.0018 17.5 1.4 0.45 9.9 0.1 2.7 3 0 0 3 3 3 2 EF hand DUF1510 PF07423.6 EWM20296.1 - 0.0056 16.0 0.5 0.0056 16.0 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) MFS_1 PF07690.11 EWM20296.1 - 0.016 13.9 6.2 3 6.4 4.7 2.1 2 0 0 2 2 2 0 Major Facilitator Superfamily Tetraspannin PF00335.15 EWM20296.1 - 0.038 13.2 0.0 0.07 12.4 0.0 1.4 1 0 0 1 1 1 0 Tetraspanin family Ion_trans PF00520.26 EWM20296.1 - 0.04 13.1 0.5 0.04 13.1 0.4 2.8 3 0 0 3 3 3 0 Ion transport protein CDC45 PF02724.9 EWM20296.1 - 0.12 10.3 7.5 0.18 9.8 5.2 1.2 1 0 0 1 1 1 0 CDC45-like protein CcmD PF04995.9 EWM20296.1 - 0.14 11.8 0.0 0.14 11.8 0.0 1.9 2 0 0 2 2 1 0 Heme exporter protein D (CcmD) DUF4611 PF15387.1 EWM20296.1 - 0.19 11.8 7.1 0.44 10.7 4.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) PBP1_TM PF14812.1 EWM20296.1 - 1.3 9.3 18.0 4 7.8 6.5 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_S49_N PF08496.5 EWM20296.1 - 4.6 7.0 8.8 5.6 6.7 0.0 2.6 3 0 0 3 3 3 0 Peptidase family S49 N-terminal Nucleoplasmin PF03066.10 EWM20296.1 - 9.7 5.6 10.6 19 4.7 7.3 1.4 1 0 0 1 1 1 0 Nucleoplasmin Ion_trans_2 PF07885.11 EWM20297.1 - 7.9e-26 89.5 21.8 5.5e-14 51.6 6.3 2.3 2 0 0 2 2 2 2 Ion channel DUF1510 PF07423.6 EWM20297.1 - 0.0043 16.4 0.5 0.0043 16.4 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) Tetraspannin PF00335.15 EWM20297.1 - 0.029 13.6 0.0 0.051 12.8 0.0 1.4 1 0 0 1 1 1 0 Tetraspanin family Ion_trans PF00520.26 EWM20297.1 - 0.032 13.4 0.5 0.032 13.4 0.4 2.7 3 0 0 3 3 3 0 Ion transport protein CDC45 PF02724.9 EWM20297.1 - 0.067 11.2 7.1 0.093 10.7 4.9 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4611 PF15387.1 EWM20297.1 - 0.096 12.8 6.4 0.2 11.8 4.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) CcmD PF04995.9 EWM20297.1 - 0.12 12.1 0.0 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Ycf1 PF05758.7 EWM20297.1 - 0.17 9.6 0.0 0.22 9.2 0.0 1.1 1 0 0 1 1 1 0 Ycf1 TRAP_alpha PF03896.11 EWM20297.1 - 0.48 9.3 2.0 0.81 8.6 1.4 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PBP1_TM PF14812.1 EWM20297.1 - 1 9.7 18.1 3.2 8.1 6.5 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_S49_N PF08496.5 EWM20297.1 - 1.1 9.1 6.6 4.2 7.1 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Nucleoplasmin PF03066.10 EWM20297.1 - 8.1 5.9 10.6 15 5.0 7.3 1.4 1 0 0 1 1 1 0 Nucleoplasmin SLR1-BP PF07333.7 EWM20299.1 - 3.4 7.9 6.2 11 6.3 0.6 2.3 1 1 1 2 2 2 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) DUF4215 PF13948.1 EWM20299.1 - 3.9 7.7 9.0 8.5 6.6 6.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4215) PLAC8 PF04749.12 EWM20303.1 - 4.7e-05 23.9 1.8 6.2e-05 23.5 1.2 1.1 1 0 0 1 1 1 1 PLAC8 family DUF4229 PF14012.1 EWM20303.1 - 3.1 7.7 10.3 0.64 9.9 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4229) p450 PF00067.17 EWM20304.1 - 0.094 11.2 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Cytochrome P450 zf-Dof PF02701.10 EWM20305.1 - 0.008 16.0 1.1 0.012 15.5 0.0 1.8 2 1 0 2 2 2 1 Dof domain, zinc finger PHO4 PF01384.15 EWM20309.1 - 5e-51 173.2 1.8 6.8e-51 172.8 1.2 1.2 1 0 0 1 1 1 1 Phosphate transporter family DUF1049 PF06305.6 EWM20309.1 - 0.039 13.4 0.1 0.31 10.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Paf1 PF03985.8 EWM20309.1 - 0.5 9.0 4.5 0.69 8.5 3.1 1.1 1 0 0 1 1 1 0 Paf1 ATP-synt_E PF05680.7 EWM20309.1 - 1.5 8.8 6.9 4.8 7.1 0.0 2.5 2 0 0 2 2 2 0 ATP synthase E chain CcmD PF04995.9 EWM20309.1 - 1.5 8.6 6.3 0.2 11.3 0.2 2.7 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) ubiquitin PF00240.18 EWM20311.1 - 3.1e-08 32.8 0.0 6.5e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Apolipoprotein PF01442.13 EWM20311.1 - 0.0032 17.0 0.2 0.0047 16.4 0.1 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Ubiquitin_2 PF14560.1 EWM20311.1 - 0.064 13.5 0.0 0.16 12.2 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-like domain Ank PF00023.25 EWM20314.1 - 6e-32 107.8 4.6 2.4e-09 36.5 0.1 5.0 4 1 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 EWM20314.1 - 2.7e-30 104.5 0.3 1.5e-16 60.4 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EWM20314.1 - 8.6e-23 79.8 1.0 5e-12 45.6 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EWM20314.1 - 5.8e-21 74.4 0.7 8.4e-09 35.7 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM20314.1 - 4e-17 60.6 0.2 3.4e-05 23.6 0.0 3.9 3 1 0 3 3 3 3 Ankyrin repeat p450 PF00067.17 EWM20316.1 - 7.6e-06 24.7 0.0 9.6e-06 24.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Daxx PF03344.10 EWM20317.1 - 0.018 13.5 14.7 0.037 12.5 10.2 1.4 1 0 0 1 1 1 0 Daxx Family DND1_DSRM PF14709.1 EWM20317.1 - 0.11 12.8 0.0 0.32 11.3 0.0 1.8 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Pkinase PF00069.20 EWM20318.1 - 2.3e-05 23.6 0.0 3.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 EWM20319.1 - 2.4e-05 23.6 0.0 3.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Metallophos PF00149.23 EWM20322.1 - 0.0036 16.7 0.1 0.0047 16.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EWM20322.1 - 0.0062 16.3 0.0 0.0087 15.9 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF1151 PF06625.6 EWM20323.1 - 1 9.0 11.3 3.7 7.2 7.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) TrkA_N PF02254.13 EWM20324.1 - 0.1 12.5 0.6 0.17 11.8 0.4 1.2 1 0 0 1 1 1 0 TrkA-N domain BNR PF02012.15 EWM20327.1 - 0.077 12.8 0.4 0.47 10.4 0.2 2.5 2 0 0 2 2 2 0 BNR/Asp-box repeat Myb_DNA-binding PF00249.26 EWM20330.1 - 1.9e-13 50.2 1.1 7.1e-12 45.1 0.1 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EWM20330.1 - 3.7e-12 46.1 0.6 1.5e-06 28.1 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain AT_hook PF02178.14 EWM20330.1 - 0.57 10.0 15.4 0.32 10.7 2.8 3.0 2 0 0 2 2 2 0 AT hook motif Gpi16 PF04113.9 EWM20336.1 - 3.3e-06 25.4 0.0 4.6e-06 24.9 0.0 1.1 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component AIG2 PF06094.7 EWM20337.1 - 1.6e-10 41.4 0.0 2.1e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family Gpi16 PF04113.9 EWM20338.1 - 1.4e-23 82.7 0.0 1.6e-23 82.5 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component RVT_2 PF07727.9 EWM20343.1 - 3.7e-47 160.3 0.0 4.2e-47 160.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNA_pol_I_A49 PF06870.7 EWM20343.1 - 0.11 11.1 0.1 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 A49-like RNA polymerase I associated factor RVT_2 PF07727.9 EWM20346.1 - 7.1e-81 270.7 0.0 1e-80 270.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-3CxxC PF13695.1 EWM20347.1 - 0.16 12.2 2.8 0.22 11.7 1.9 1.3 1 0 0 1 1 1 0 Zinc-binding domain zf-AN1 PF01428.11 EWM20355.1 - 7.5e-06 25.7 8.3 1.1e-05 25.1 5.7 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger GHL15 PF14885.1 EWM20359.1 - 0.33 11.1 1.8 36 4.6 0.1 3.2 3 0 0 3 3 3 0 Hypothetical glycosyl hydrolase family 15 Aconitase_C PF00694.14 EWM20360.1 - 0.0016 18.5 0.1 0.0036 17.4 0.0 1.8 1 1 0 1 1 1 1 Aconitase C-terminal domain Acyltransferase PF01553.16 EWM20361.1 - 6e-21 74.2 0.0 8e-20 70.6 0.0 2.2 2 0 0 2 2 2 1 Acyltransferase MORN PF02493.15 EWM20365.1 - 5.5e-23 79.2 27.6 7.9e-06 25.3 0.2 7.9 7 1 0 7 7 7 7 MORN repeat Beta_helix PF13229.1 EWM20365.1 - 0.36 10.5 3.6 0.53 10.0 2.5 1.3 1 0 0 1 1 1 0 Right handed beta helix region HTH_29 PF13551.1 EWM20369.1 - 0.026 14.6 0.6 0.037 14.1 0.2 1.3 1 1 0 1 1 1 0 Winged helix-turn helix Herpes_UL49_1 PF03117.9 EWM20370.1 - 0.062 12.3 0.4 0.09 11.8 0.3 1.2 1 1 0 1 1 1 0 UL49 family POM121 PF15229.1 EWM20371.1 - 0.043 13.2 0.5 0.064 12.6 0.3 1.5 1 1 0 1 1 1 0 POM121 family Glycos_transf_2 PF00535.21 EWM20379.1 - 0.00062 19.4 0.0 0.00084 19.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF2608 PF11019.3 EWM20379.1 - 0.016 14.2 0.0 0.019 13.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) zf-CCHC PF00098.18 EWM20381.1 - 0.0024 17.7 16.3 0.0074 16.1 3.2 2.8 2 0 0 2 2 2 2 Zinc knuckle eIF3g PF12353.3 EWM20381.1 - 0.044 13.7 0.4 0.044 13.7 0.3 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_4 PF14392.1 EWM20381.1 - 0.046 13.3 11.2 0.25 11.0 1.1 3.1 3 1 0 3 3 3 0 Zinc knuckle zf-CCHC_3 PF13917.1 EWM20381.1 - 0.15 11.7 11.4 0.057 13.1 1.8 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.1 EWM20381.1 - 0.28 10.6 15.5 0.45 10.0 1.4 3.0 2 1 1 3 3 3 0 GAG-polyprotein viral zinc-finger UBN2_2 PF14227.1 EWM20382.1 - 0.005 16.3 0.2 0.0076 15.7 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type NUDIX_4 PF14815.1 EWM20382.1 - 0.054 12.9 0.2 0.081 12.3 0.2 1.4 1 1 0 1 1 1 0 NUDIX domain Ku PF02735.11 EWM20383.1 - 0.065 12.6 4.4 0.12 11.7 3.1 1.5 1 0 0 1 1 1 0 Ku70/Ku80 beta-barrel domain AAA_11 PF13086.1 EWM20383.1 - 0.079 12.5 9.2 7 6.1 6.1 2.1 2 0 0 2 2 2 0 AAA domain Fmp27 PF10344.4 EWM20383.1 - 0.34 8.5 10.2 0.53 7.9 7.1 1.2 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 SAPS PF04499.10 EWM20383.1 - 0.45 9.0 8.0 0.49 8.9 5.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein EIIBC-GUT_N PF03612.9 EWM20383.1 - 1.2 8.6 9.6 2.8 7.5 4.9 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus RNase_H2-Ydr279 PF09468.5 EWM20383.1 - 1.6 7.8 12.9 2.9 7.0 8.9 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) FAM176 PF14851.1 EWM20383.1 - 3.1 7.4 15.5 5.1 6.7 6.3 2.4 2 0 0 2 2 2 0 FAM176 family Peptidase_S49_N PF08496.5 EWM20383.1 - 5 6.8 13.7 5.3 6.8 8.3 1.8 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF1428 PF07237.6 EWM20385.1 - 0.031 14.1 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) RVT_2 PF07727.9 EWM20386.1 - 4.9e-63 212.3 0.0 5.9e-63 212.0 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNA_pol_I_A49 PF06870.7 EWM20386.1 - 0.079 11.5 0.1 0.15 10.6 0.0 1.4 1 0 0 1 1 1 0 A49-like RNA polymerase I associated factor Rtf2 PF04641.7 EWM20387.1 - 5.6e-10 38.8 1.4 0.00017 20.9 0.0 3.3 2 2 1 3 3 3 2 Rtf2 RING-finger zf-Nse PF11789.3 EWM20387.1 - 1.5e-06 27.6 0.0 5.1e-05 22.6 0.0 2.5 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 EWM20387.1 - 3.1e-05 23.8 0.1 0.00059 19.7 0.0 2.9 3 0 0 3 3 3 1 U-box domain Ribosomal_L10 PF00466.15 EWM20387.1 - 0.074 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L10 DUF853 PF05872.7 EWM20387.1 - 0.17 10.2 0.6 0.24 9.6 0.4 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) TMEM18 PF14770.1 EWM20389.1 - 0.083 12.4 2.3 0.088 12.3 1.2 1.4 1 1 0 1 1 1 0 Transmembrane protein 18 Hormone_6 PF00236.13 EWM20390.1 - 0.057 13.2 0.2 0.09 12.6 0.1 1.3 1 0 0 1 1 1 0 Glycoprotein hormone p450 PF00067.17 EWM20393.1 - 1.7e-34 119.1 0.0 2.4e-21 75.7 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.17 EWM20396.1 - 0.16 10.4 0.0 0.19 10.2 0.0 1.1 1 0 0 1 1 1 0 Cytochrome P450 Macro PF01661.16 EWM20398.1 - 2e-13 50.2 0.0 5.8e-13 48.7 0.0 1.8 2 1 0 2 2 2 1 Macro domain IFT43 PF15305.1 EWM20398.1 - 0.082 12.9 2.7 0.15 12.0 1.9 1.4 1 0 0 1 1 1 0 Intraflagellar transport protein 43 Macoilin PF09726.4 EWM20398.1 - 7.7 4.6 7.8 11 4.1 5.4 1.1 1 0 0 1 1 1 0 Transmembrane protein UBA_4 PF14555.1 EWM20399.1 - 5.1e-12 45.1 0.0 8.5e-12 44.4 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain SAP PF02037.22 EWM20399.1 - 3.9e-06 26.2 0.4 7e-06 25.4 0.2 1.5 1 0 0 1 1 1 1 SAP domain UBA PF00627.26 EWM20399.1 - 0.0036 17.0 0.0 0.0067 16.2 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Telomere_Sde2_2 PF13297.1 EWM20399.1 - 0.087 12.1 0.1 0.16 11.2 0.1 1.4 1 0 0 1 1 1 0 Telomere stability C-terminal Arylsulfotrans PF05935.6 EWM20400.1 - 0.13 10.7 0.0 0.32 9.4 0.0 1.5 1 1 1 2 2 2 0 Arylsulfotransferase (ASST) Proteasome PF00227.21 EWM20402.1 - 1.2e-14 54.0 0.0 1e-07 31.4 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit DUF4057 PF13266.1 EWM20404.1 - 0.0088 15.5 0.7 0.012 15.1 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4057) MFS_1 PF07690.11 EWM20408.1 - 8.1e-15 54.3 18.5 9.5e-15 54.1 12.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EWM20408.1 - 0.0018 18.0 0.3 0.0045 16.7 0.0 1.8 2 0 0 2 2 2 1 MFS_1 like family MFS_3 PF05977.8 EWM20408.1 - 0.0031 15.6 6.4 0.0037 15.4 4.4 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector Herpes_TAF50 PF03326.8 EWM20411.1 - 0.057 12.3 0.5 0.067 12.1 0.4 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) PHD PF00628.24 EWM20412.1 - 3.3e-07 29.8 1.1 6.3e-07 28.9 0.8 1.4 1 0 0 1 1 1 1 PHD-finger Heme_oxygenase PF01126.15 EWM20414.1 - 5.7e-29 101.1 0.0 7.1e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Heme oxygenase RFC1 PF08519.7 EWM20414.1 - 0.016 14.9 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain MMR_HSR1 PF01926.18 EWM20415.1 - 3.6e-13 49.4 0.0 5.6e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EWM20415.1 - 1.1e-07 31.5 0.0 1.4e-05 24.5 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EWM20415.1 - 0.023 13.9 0.0 0.049 12.9 0.0 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B Dynamin_N PF00350.18 EWM20415.1 - 0.033 13.9 0.1 3.6 7.3 0.2 2.2 2 0 0 2 2 2 0 Dynamin family DUF258 PF03193.11 EWM20415.1 - 0.044 12.9 0.0 0.088 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 IIGP PF05049.8 EWM20415.1 - 0.087 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) GFO_IDH_MocA PF01408.17 EWM20418.1 - 9e-26 90.7 0.8 1.4e-25 90.1 0.5 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EWM20418.1 - 8e-12 44.9 0.0 1.4e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Saccharop_dh PF03435.13 EWM20418.1 - 0.00044 19.3 0.5 0.00062 18.8 0.3 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 EWM20418.1 - 0.0012 19.1 0.1 0.0025 18.1 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EWM20418.1 - 0.0014 19.0 0.1 0.0028 18.0 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_3 PF03447.11 EWM20418.1 - 0.0027 18.1 0.0 0.0052 17.1 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain TrkA_N PF02254.13 EWM20418.1 - 0.0037 17.2 0.1 0.0061 16.5 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain NeuB PF03102.9 EWM20418.1 - 0.0089 15.1 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 NeuB family Shikimate_DH PF01488.15 EWM20418.1 - 0.012 15.7 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 EWM20418.1 - 0.043 12.9 0.0 0.085 12.0 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EWM20418.1 - 0.07 13.3 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding HGD-D PF06050.8 EWM20418.1 - 0.084 11.6 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component YCII PF03795.9 EWM20419.1 - 1.5e-07 31.4 0.1 2.7e-07 30.6 0.1 1.4 1 1 0 1 1 1 1 YCII-related domain SMC_hinge PF06470.8 EWM20420.1 - 1e-09 38.3 0.0 3.2e-09 36.7 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain Reo_sigmaC PF04582.7 EWM20420.1 - 4.3e-06 26.1 19.0 0.00028 20.2 0.9 3.8 3 1 0 3 3 3 3 Reovirus sigma C capsid protein Trichoplein PF13868.1 EWM20421.1 - 0.12 10.7 4.8 0.15 10.4 3.3 1.1 1 0 0 1 1 1 0 Tumour suppressor, Mitostatin Rep_fac_C PF08542.6 EWM20422.1 - 1.2e-17 63.6 0.0 2.2e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EWM20422.1 - 1.4e-13 50.8 0.0 3.9e-13 49.3 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EWM20422.1 - 3e-11 43.6 0.0 6.8e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EWM20422.1 - 2.6e-06 27.5 0.1 0.00019 21.4 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.10 EWM20422.1 - 3e-06 26.2 0.0 0.0014 17.3 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 EWM20422.1 - 9e-06 25.3 0.0 3.7e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain Mg_chelatase PF01078.16 EWM20422.1 - 1.7e-05 24.0 0.0 0.00076 18.7 0.0 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 EWM20422.1 - 1.8e-05 23.9 0.0 4.6e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EWM20422.1 - 7.2e-05 22.9 0.0 0.00049 20.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 EWM20422.1 - 0.0075 15.0 0.0 0.14 10.8 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus AAA_11 PF13086.1 EWM20422.1 - 0.0083 15.7 0.0 0.017 14.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EWM20422.1 - 0.0091 15.4 0.1 0.022 14.2 0.0 1.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family DEAD PF00270.24 EWM20422.1 - 0.015 14.8 0.0 0.39 10.1 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_5 PF07728.9 EWM20422.1 - 0.015 15.0 0.0 0.77 9.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 EWM20422.1 - 0.016 14.6 0.1 5.9 6.2 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_30 PF13604.1 EWM20422.1 - 0.04 13.4 0.3 0.69 9.4 0.2 2.3 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EWM20422.1 - 0.054 12.8 0.0 0.28 10.5 0.0 2.1 3 0 0 3 3 3 0 AAA domain Trypsin_2 PF13365.1 EWM20423.1 - 5.6e-05 23.1 0.0 0.00062 19.7 0.0 2.5 2 1 0 2 2 2 1 Trypsin-like peptidase domain Trypsin_2 PF13365.1 EWM20424.1 - 5.6e-05 23.1 0.0 0.00062 19.7 0.0 2.5 2 1 0 2 2 2 1 Trypsin-like peptidase domain Sad1_UNC PF07738.8 EWM20425.1 - 3.9e-09 36.4 0.0 8.4e-09 35.3 0.0 1.5 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal RD3 PF14473.1 EWM20425.1 - 0.21 11.0 7.4 0.25 10.7 0.1 2.6 3 0 0 3 3 3 0 RD3 protein Choline_transpo PF04515.7 EWM20426.1 - 7.8e-24 84.0 0.2 9.2e-24 83.7 0.2 1.1 1 0 0 1 1 1 1 Plasma-membrane choline transporter Choline_transpo PF04515.7 EWM20427.1 - 2e-33 115.5 2.9 2.2e-33 115.4 2.0 1.0 1 0 0 1 1 1 1 Plasma-membrane choline transporter DUF307 PF03733.8 EWM20427.1 - 0.22 11.9 0.3 0.22 11.9 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF307) MS_channel PF00924.13 EWM20427.1 - 0.47 9.7 4.7 0.7 9.1 3.3 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel SPC12 PF06645.8 EWM20427.1 - 0.5 10.2 3.5 0.39 10.5 0.2 2.2 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) FtsX PF02687.16 EWM20427.1 - 1.6 8.5 6.8 3.6 7.3 4.5 1.7 1 1 1 2 2 2 0 FtsX-like permease family DUF3681 PF12442.3 EWM20430.1 - 0.045 13.9 0.8 0.078 13.1 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3681) DHH PF01368.15 EWM20431.1 - 7.9e-13 48.2 0.0 4.2e-12 45.9 0.0 2.0 1 1 0 1 1 1 1 DHH family CKS PF01111.14 EWM20432.1 - 6.5e-38 128.4 0.5 8.1e-38 128.1 0.3 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit APC_15aa PF05972.6 EWM20432.1 - 3.2 7.9 5.4 0.88 9.6 0.8 2.1 2 0 0 2 2 2 0 APC 15 residue motif CKS PF01111.14 EWM20433.1 - 3.4e-38 129.2 0.5 3.8e-38 129.1 0.3 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Lipoprotein_19 PF13617.1 EWM20440.1 - 0.68 9.6 2.3 0.36 10.4 0.3 1.5 2 0 0 2 2 2 0 YnbE-like lipoprotein DHFR_1 PF00186.14 EWM20443.1 - 7.4e-11 41.8 0.0 1.3e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Dihydrofolate reductase PPR_3 PF13812.1 EWM20444.1 - 0.069 13.4 0.0 3 8.3 0.0 2.6 2 0 0 2 2 2 0 Pentatricopeptide repeat domain PPR_2 PF13041.1 EWM20446.1 - 0.11 12.4 0.0 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 PPR repeat family Metallophos PF00149.23 EWM20450.1 - 4.2e-07 29.5 0.2 5.3e-07 29.2 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EWM20450.1 - 0.067 13.0 0.0 0.081 12.7 0.0 1.1 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Sep15_SelM PF08806.6 EWM20456.1 - 0.0059 16.3 0.0 0.0084 15.8 0.0 1.3 1 0 0 1 1 1 1 Sep15/SelM redox domain Peptidase_S10 PF00450.17 EWM20460.1 - 2.3e-14 53.4 0.0 3e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.17 EWM20461.1 - 6.4e-16 58.5 0.6 7.7e-16 58.2 0.4 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Lipoxygenase PF00305.14 EWM20464.1 - 0.0027 15.7 0.2 0.0043 15.1 0.1 1.3 1 1 0 1 1 1 1 Lipoxygenase Aminotran_1_2 PF00155.16 EWM20466.1 - 1.3e-10 40.7 0.0 6.1e-09 35.3 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class I and II Methyltransf_21 PF05050.7 EWM20468.1 - 3e-06 27.2 0.0 4.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain rve PF00665.21 EWM20469.1 - 3.9e-21 75.3 0.0 6.1e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EWM20469.1 - 8.6e-08 31.7 0.0 1.6e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 EWM20469.1 - 0.11 11.9 0.0 0.33 10.5 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain RVT_2 PF07727.9 EWM20471.1 - 9.8e-64 214.6 0.0 1.2e-63 214.3 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNA_pol_I_A49 PF06870.7 EWM20471.1 - 0.067 11.7 0.1 0.12 10.9 0.0 1.4 1 0 0 1 1 1 0 A49-like RNA polymerase I associated factor zf-CCHC PF00098.18 EWM20477.1 - 0.011 15.6 4.7 0.011 15.6 3.2 3.0 3 0 0 3 3 3 0 Zinc knuckle eIF3g PF12353.3 EWM20477.1 - 0.025 14.5 0.9 0.051 13.5 0.6 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_4 PF14392.1 EWM20477.1 - 0.56 9.9 10.0 3.1 7.5 0.4 3.2 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_3 PF13917.1 EWM20477.1 - 0.58 9.9 9.7 0.12 12.1 1.5 2.3 2 0 0 2 2 2 0 Zinc knuckle Hydrolase_like2 PF13246.1 EWM20479.1 - 6e-10 38.9 0.0 8.7e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit TPP_enzyme_C PF02775.16 EWM20480.1 - 0.15 11.6 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Cation_ATPase_N PF00690.21 EWM20481.1 - 7.4e-15 54.1 0.0 1.4e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus E1-E2_ATPase PF00122.15 EWM20481.1 - 1.2e-07 31.0 0.9 5.8e-07 28.7 0.0 1.9 1 1 1 2 2 2 1 E1-E2 ATPase Cyt_c_ox_IV PF12270.3 EWM20481.1 - 0.074 12.7 1.0 0.11 12.2 0.7 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV PT PF04886.7 EWM20483.1 - 4.6e-46 153.8 180.4 1.5e+04 -126.0 125.0 10.6 1 1 0 1 1 1 0 PT repeat PT PF04886.7 EWM20486.1 - 1.2e-20 72.5 101.8 3.3e-06 26.3 20.5 4.1 1 1 3 4 4 4 3 PT repeat WD40 PF00400.27 EWM20487.1 - 0.0027 17.5 0.6 5.3 7.0 0.0 3.6 4 0 0 4 4 4 2 WD domain, G-beta repeat Sulfotransfer_3 PF13469.1 EWM20489.1 - 2.1e-05 25.5 0.5 8.3e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Sulfotransferase family LSR PF05624.9 EWM20489.1 - 7 6.4 7.7 1.5 8.6 2.8 1.8 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) PSS PF03034.10 EWM20490.1 - 2.6e-62 210.7 11.2 3.5e-62 210.3 7.8 1.1 1 0 0 1 1 1 1 Phosphatidyl serine synthase EF_TS PF00889.14 EWM20492.1 - 1.2e-14 54.1 0.2 1.7e-14 53.6 0.2 1.2 1 0 0 1 1 1 1 Elongation factor TS UBA PF00627.26 EWM20492.1 - 3.2e-07 30.0 0.0 8.2e-07 28.6 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain 2OG-FeII_Oxy_3 PF13640.1 EWM20493.1 - 2.7e-18 66.3 0.1 4.2e-18 65.7 0.1 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EWM20493.1 - 1.4e-09 37.4 0.2 7e-08 32.0 0.0 2.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.1 EWM20493.1 - 0.017 15.3 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy PF03171.15 EWM20493.1 - 0.098 12.9 0.0 0.23 11.7 0.0 1.6 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily SR-25 PF10500.4 EWM20494.1 - 0.00085 18.8 7.4 0.001 18.5 5.1 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 EWM20494.1 - 0.15 11.4 2.4 0.22 10.8 1.7 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF755 PF05501.6 EWM20494.1 - 2.2 8.3 13.0 3 7.8 9.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF2890 PF11081.3 EWM20498.1 - 0.089 12.8 2.5 0.11 12.5 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Methyltransf_23 PF13489.1 EWM20508.1 - 7.4e-09 35.5 0.0 1.2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM20508.1 - 9.3e-09 35.0 0.0 1.7e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM20508.1 - 5e-06 27.0 0.0 9.1e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM20508.1 - 3.5e-05 24.2 0.0 7.5e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EWM20508.1 - 0.0001 21.4 0.0 0.0002 20.5 0.0 1.5 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EWM20508.1 - 0.0017 18.8 0.0 0.0041 17.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM20508.1 - 0.0027 18.0 0.0 0.0075 16.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 EWM20508.1 - 0.037 13.5 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Aminotran_1_2 PF00155.16 EWM20510.1 - 0.0011 18.0 0.0 0.1 11.5 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_1_2 PF00155.16 EWM20511.1 - 0.11 11.4 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II Sulfotransfer_2 PF03567.9 EWM20514.1 - 0.0014 18.3 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Epimerase PF01370.16 EWM20515.1 - 2.9e-37 128.3 0.0 3.7e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EWM20515.1 - 1.7e-10 40.2 0.0 8.2e-09 34.7 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EWM20515.1 - 1.9e-09 36.6 0.0 2.6e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EWM20515.1 - 1.6e-08 33.7 0.0 3.2e-08 32.7 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EWM20515.1 - 1.1e-06 28.6 0.0 1.7e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EWM20515.1 - 4.7e-06 26.3 0.0 6.8e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 EWM20515.1 - 0.00083 18.3 0.0 0.004 16.1 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein DUF616 PF04765.8 EWM20516.1 - 4.6e-09 35.8 0.0 6.2e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF616) Epimerase_Csub PF13950.1 EWM20516.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit Epimerase PF01370.16 EWM20516.1 - 0.11 11.8 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family IspD PF01128.14 EWM20517.1 - 0.11 11.9 0.1 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YcgR PF07317.7 EWM20518.1 - 0.11 12.2 0.1 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Flagellar regulator YcgR Ank_2 PF12796.2 EWM20522.1 - 6.5e-42 141.7 5.2 1.3e-19 70.3 0.1 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EWM20522.1 - 3.9e-28 95.8 4.4 3.7e-09 35.9 0.0 4.8 6 1 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 EWM20522.1 - 2.3e-27 94.8 0.3 2.5e-12 46.9 0.0 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EWM20522.1 - 7.7e-20 70.4 1.0 8.5e-11 41.7 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM20522.1 - 6e-18 63.1 1.9 5.5e-05 23.0 0.0 4.5 5 0 0 5 5 5 3 Ankyrin repeat DUF612 PF04747.7 EWM20522.1 - 0.098 11.5 1.7 0.12 11.3 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF612 Rhomboid PF01694.17 EWM20523.1 - 0.002 18.1 8.5 0.002 18.1 5.9 1.6 2 0 0 2 2 2 1 Rhomboid family DUF3784 PF12650.2 EWM20523.1 - 0.031 14.1 0.4 0.031 14.1 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF1751 PF08551.5 EWM20523.1 - 0.21 11.9 3.2 0.2 12.0 1.3 1.7 1 1 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) Carb_anhydrase PF00194.16 EWM20524.1 - 1.1e-14 54.0 0.0 5.8e-14 51.6 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.16 EWM20525.1 - 6e-16 58.1 0.0 2.5e-15 56.1 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Peptidase_C2 PF00648.16 EWM20533.1 - 8.2e-07 28.3 0.1 0.0029 16.6 0.1 2.1 2 0 0 2 2 2 2 Calpain family cysteine protease Exo_endo_phos PF03372.18 EWM20536.1 - 0.1 12.4 0.3 0.11 12.3 0.2 1.1 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF4551 PF15087.1 EWM20536.1 - 0.53 8.5 3.9 0.63 8.3 2.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Apt1 PF10351.4 EWM20536.1 - 6.1 5.5 6.6 7.6 5.2 4.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Exo_endo_phos PF03372.18 EWM20538.1 - 4.3e-07 30.1 0.0 5.9e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Na_H_Exchanger PF00999.16 EWM20543.1 - 2.5e-07 29.5 2.6 3.4e-07 29.1 1.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF4345 PF14248.1 EWM20543.1 - 0.015 14.7 0.3 0.02 14.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4345) DUF4153 PF13687.1 EWM20543.1 - 0.048 13.1 0.1 0.057 12.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4153) OCIA PF07051.6 EWM20543.1 - 0.16 11.3 0.5 0.35 10.2 0.4 1.5 1 1 0 1 1 1 0 Ovarian carcinoma immunoreactive antigen (OCIA) DUF1469 PF07332.6 EWM20543.1 - 0.21 11.3 3.7 0.3 10.8 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Ribosomal_L4 PF00573.17 EWM20545.1 - 2.8e-38 131.2 5.0 4e-38 130.7 3.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Mito_fiss_reg PF05308.6 EWM20545.1 - 0.013 14.8 4.6 0.021 14.1 3.2 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 EWM20545.1 - 0.48 9.6 9.3 0.75 9.0 6.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SURF1 PF02104.10 EWM20548.1 - 2e-14 53.9 0.0 2.6e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 SURF1 family Peptidase_M3 PF01432.15 EWM20550.1 - 3.8e-11 42.7 0.0 4.1e-11 42.6 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M3 Glyco_hydro_9 PF00759.14 EWM20555.1 - 3.9e-122 408.3 11.5 4.6e-122 408.1 8.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Longin PF13774.1 EWM20557.1 - 6.8e-23 80.0 0.0 9.7e-23 79.5 0.0 1.2 1 0 0 1 1 1 1 Regulated-SNARE-like domain 2OG-FeII_Oxy PF03171.15 EWM20558.1 - 9.7e-19 67.5 0.0 1.4e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Synaptobrevin PF00957.16 EWM20559.1 - 0.0013 18.2 0.0 0.0021 17.6 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin DIOX_N PF14226.1 EWM20560.1 - 1.3e-16 61.1 0.0 1.6e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Corona_NS8 PF12093.3 EWM20562.1 - 0.044 14.1 0.0 0.056 13.8 0.0 1.1 1 0 0 1 1 1 0 Coronavirus NS8 protein 1-cysPrx_C PF10417.4 EWM20562.1 - 0.11 12.1 0.8 0.23 11.1 0.2 1.7 2 0 0 2 2 2 0 C-terminal domain of 1-Cys peroxiredoxin TMF_DNA_bd PF12329.3 EWM20563.1 - 0.0036 17.0 7.2 0.0043 16.8 5.0 1.1 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding PX PF00787.19 EWM20563.1 - 0.017 14.9 0.6 0.022 14.5 0.4 1.3 1 1 0 1 1 1 0 PX domain GAS PF13851.1 EWM20563.1 - 0.042 13.0 8.0 0.051 12.7 5.6 1.0 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding MCC-bdg_PDZ PF10506.4 EWM20563.1 - 0.044 13.6 5.6 0.08 12.7 3.4 1.7 1 1 1 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Tropomyosin_1 PF12718.2 EWM20563.1 - 0.059 13.2 8.2 0.072 12.9 5.7 1.0 1 0 0 1 1 1 0 Tropomyosin like RTBV_P46 PF06216.6 EWM20563.1 - 0.15 10.9 2.0 0.17 10.6 1.4 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein TMF_TATA_bd PF12325.3 EWM20563.1 - 0.22 11.2 7.4 0.28 10.9 5.1 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding ATG16 PF08614.6 EWM20563.1 - 0.26 11.1 5.5 0.3 10.9 3.8 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) ADIP PF11559.3 EWM20563.1 - 0.29 11.0 6.6 0.38 10.6 4.5 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Fzo_mitofusin PF04799.8 EWM20563.1 - 0.79 9.0 3.0 1.1 8.6 2.1 1.2 1 0 0 1 1 1 0 fzo-like conserved region Lge1 PF11488.3 EWM20563.1 - 1 9.5 4.0 1.5 9.0 2.8 1.3 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 DivIC PF04977.10 EWM20563.1 - 1.6 8.2 6.0 6.9 6.2 1.9 2.3 1 1 1 2 2 2 0 Septum formation initiator APG6 PF04111.7 EWM20563.1 - 1.9 7.4 5.5 1.9 7.4 3.8 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EWM20563.1 - 1.9 8.0 6.5 2.3 7.7 4.5 1.1 1 0 0 1 1 1 0 IncA protein bZIP_2 PF07716.10 EWM20563.1 - 4.4 7.2 13.7 12 5.8 3.7 2.9 1 1 2 3 3 3 0 Basic region leucine zipper PNRC PF15365.1 EWM20564.1 - 0.047 13.7 1.2 0.074 13.0 0.8 1.3 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator CobW_C PF07683.9 EWM20566.1 - 2.9e-20 71.7 1.8 1.5e-19 69.5 1.2 2.1 1 1 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain MCM_N PF14551.1 EWM20572.1 - 0.00043 20.7 0.0 0.0006 20.2 0.0 1.2 1 0 0 1 1 1 1 MCM N-terminal domain Oxidored_molyb PF00174.14 EWM20573.1 - 6.3e-50 168.8 0.0 1.1e-49 168.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EWM20573.1 - 5.1e-49 165.2 0.1 9.3e-49 164.4 0.1 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.23 EWM20573.1 - 3.7e-23 81.1 0.0 7e-23 80.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NIR_SIR PF01077.17 EWM20575.1 - 1.7e-33 115.1 0.0 3.1e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 EWM20575.1 - 1.2e-16 60.1 0.1 2.3e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain MMR_HSR1 PF01926.18 EWM20578.1 - 1.9e-09 37.4 0.0 2.5e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP1_OBG PF01018.17 EWM20578.1 - 1.6e-06 27.8 0.1 2.4e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 GTP1/OBG FeoB_N PF02421.13 EWM20578.1 - 5.1e-05 22.5 0.0 6.6e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_29 PF13555.1 EWM20578.1 - 0.056 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.1 EWM20578.1 - 0.065 13.1 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EWM20578.1 - 0.076 13.3 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 ABC transporter ArgK PF03308.11 EWM20578.1 - 0.1 11.3 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 ArgK protein MobB PF03205.9 EWM20578.1 - 0.16 11.7 0.0 1 9.0 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ECR1_N PF14382.1 EWM20579.1 - 8.7e-05 21.7 2.0 0.033 13.4 0.3 3.4 2 1 0 2 2 2 2 Exosome complex exonuclease RRP4 N-terminal region Ins134_P3_kin PF05770.6 EWM20582.1 - 0.00042 19.4 0.0 0.0018 17.3 0.0 1.7 1 1 0 1 1 1 1 Inositol 1, 3, 4-trisphosphate 5/6-kinase FAM75 PF14650.1 EWM20582.1 - 3.6 6.8 6.4 4.8 6.4 4.5 1.1 1 0 0 1 1 1 0 FAM75 family zf-RING_2 PF13639.1 EWM20583.1 - 4.8e-13 48.7 10.0 7.5e-13 48.0 6.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EWM20583.1 - 5.2e-08 32.4 7.4 8.1e-08 31.8 5.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EWM20583.1 - 9.2e-07 28.7 8.1 1.4e-06 28.2 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EWM20583.1 - 2.5e-06 27.0 5.3 4.1e-06 26.3 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EWM20583.1 - 5.5e-06 25.9 7.6 8.3e-06 25.3 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EWM20583.1 - 5.7e-06 26.3 6.4 1e-05 25.5 4.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EWM20583.1 - 0.0073 16.1 2.9 0.014 15.2 2.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EWM20583.1 - 0.094 12.4 2.8 0.15 11.7 2.0 1.4 1 0 0 1 1 1 0 RING-type zinc-finger RINGv PF12906.2 EWM20583.1 - 0.49 10.4 8.0 0.96 9.5 5.6 1.5 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.24 EWM20583.1 - 0.5 10.0 8.4 0.84 9.3 5.8 1.4 1 0 0 1 1 1 0 PHD-finger Trypan_PARP PF05887.6 EWM20583.1 - 0.65 9.8 6.2 1.6 8.5 4.3 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Enterotoxin_HS1 PF08090.6 EWM20584.1 - 0.1 12.3 0.6 0.1 12.3 0.4 2.1 2 0 0 2 2 2 0 Heat stable E.coli enterotoxin 1 CorA PF01544.13 EWM20585.1 - 6.5e-06 25.3 1.2 7.6e-06 25.1 0.8 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ATPgrasp_ST PF14397.1 EWM20586.1 - 1e-11 44.4 0.0 4.5e-10 39.1 0.0 2.8 2 2 0 2 2 2 2 Sugar-transfer associated ATP-grasp AMP-binding PF00501.23 EWM20588.1 - 2.7e-87 292.8 0.0 3.5e-87 292.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EWM20588.1 - 3.6e-05 24.6 0.3 0.00012 22.9 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ribosomal_L7Ae PF01248.21 EWM20590.1 - 7.3e-23 79.9 0.0 9.5e-23 79.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CN_hydrolase PF00795.17 EWM20591.1 - 1.9e-29 102.3 0.0 2.7e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase AP_endonuc_2 PF01261.19 EWM20591.1 - 0.1 11.8 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Fe_hyd_lg_C PF02906.9 EWM20592.1 - 3e-37 128.4 0.0 3.3e-35 121.7 0.0 2.4 2 1 0 2 2 2 2 Iron only hydrogenase large subunit, C-terminal domain DUF605 PF04652.11 EWM20593.1 - 2.5e-17 63.3 0.0 2.9e-17 63.1 0.0 1.0 1 0 0 1 1 1 1 Vta1 like Methyltransf_28 PF02636.12 EWM20594.1 - 5.3e-16 58.7 0.0 9.1e-16 58.0 0.0 1.3 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase HpcH_HpaI PF03328.9 EWM20597.1 - 4.1e-21 74.8 0.0 5.3e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.13 EWM20597.1 - 0.00021 20.2 0.0 0.00025 20.0 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain C-C_Bond_Lyase PF15617.1 EWM20597.1 - 0.021 13.6 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 C-C_Bond_Lyase of the TIM-Barrel fold Aminotran_3 PF00202.16 EWM20598.1 - 8.8e-102 340.4 0.0 1.1e-101 340.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III BATS PF06968.8 EWM20601.1 - 4.9e-21 74.3 0.0 7.3e-21 73.8 0.0 1.2 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain RRM_1 PF00076.17 EWM20603.1 - 1.7e-15 56.4 0.1 2.3e-15 55.9 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM20603.1 - 2.4e-11 43.4 0.1 3.6e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM20603.1 - 6.8e-08 32.2 0.0 9.9e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EWM20603.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 PP2C PF00481.16 EWM20604.1 - 6.4e-20 71.6 0.0 3.2e-19 69.3 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C Pkinase PF00069.20 EWM20605.1 - 1.4e-16 60.4 0.0 1.7e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM20605.1 - 4.2e-05 22.7 0.0 5.1e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EWM20605.1 - 0.044 12.7 0.0 0.08 11.8 0.0 1.3 1 1 0 1 1 1 0 Kinase-like Pkinase_Tyr PF07714.12 EWM20610.1 - 4.4e-09 35.7 0.0 5.2e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EWM20610.1 - 0.044 12.9 0.0 0.053 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Med4 PF10018.4 EWM20611.1 - 0.00068 19.0 0.1 0.00068 19.0 0.0 2.0 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 Ribosomal_60s PF00428.14 EWM20611.1 - 0.082 13.3 5.2 0.1 13.0 2.1 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF21 PF01595.15 EWM20612.1 - 0.071 12.3 0.0 0.091 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF21 ApbA_C PF08546.6 EWM20614.1 - 2.4e-15 56.6 0.0 1e-14 54.5 0.0 1.8 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal C4 PF01413.14 EWM20616.1 - 0.055 13.3 0.3 0.36 10.7 0.0 2.3 2 0 0 2 2 2 0 C-terminal tandem repeated domain in type 4 procollagen ApbA PF02558.11 EWM20619.1 - 1.5e-07 30.9 0.0 2e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DAO PF01266.19 EWM20619.1 - 0.0013 17.7 0.0 0.0016 17.4 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EWM20619.1 - 0.0051 16.8 0.0 0.0079 16.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EWM20619.1 - 0.0083 16.5 0.0 0.012 15.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EWM20619.1 - 0.014 15.4 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase KR PF08659.5 EWM20619.1 - 0.059 13.0 0.0 0.087 12.4 0.0 1.1 1 0 0 1 1 1 0 KR domain GMC_oxred_N PF00732.14 EWM20619.1 - 0.066 12.3 0.0 0.082 12.0 0.0 1.1 1 0 0 1 1 1 0 GMC oxidoreductase 4HBT_3 PF13622.1 EWM20619.1 - 0.29 10.8 11.9 3.2 7.4 8.2 1.9 1 1 0 1 1 1 0 Thioesterase-like superfamily Sugar_tr PF00083.19 EWM20620.1 - 3e-15 55.7 8.6 3.9e-15 55.3 6.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EWM20620.1 - 0.72 8.5 16.7 3.1 6.4 11.4 1.7 1 1 0 1 1 1 0 Major Facilitator Superfamily DUF3586 PF12131.3 EWM20623.1 - 4.5e-05 23.4 0.2 9.4e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3586) CX PF01705.14 EWM20625.1 - 0.041 13.8 0.0 0.075 13.0 0.0 1.4 1 0 0 1 1 1 0 CX module Pheromone PF08015.6 EWM20630.1 - 4.7 8.1 9.6 0.54 11.1 1.1 2.6 2 0 0 2 2 2 0 Fungal mating-type pheromone ArfGap PF01412.13 EWM20631.1 - 8.3e-30 102.9 0.1 1.1e-29 102.5 0.1 1.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Zn_Tnp_IS1595 PF12760.2 EWM20631.1 - 0.18 11.6 0.9 0.81 9.5 0.5 2.0 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Proteasome PF00227.21 EWM20632.1 - 6.3e-43 146.2 0.0 9.1e-43 145.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EWM20632.1 - 8.1e-14 50.6 0.1 1.4e-13 49.8 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature uDENN PF03456.13 EWM20633.1 - 7.1e-15 54.7 0.0 1.9e-14 53.3 0.0 1.8 1 0 0 1 1 1 1 uDENN domain DENN PF02141.16 EWM20633.1 - 0.0046 16.6 0.4 0.78 9.4 0.0 2.3 2 0 0 2 2 2 2 DENN (AEX-3) domain P16-Arc PF04699.9 EWM20635.1 - 0.14 12.1 0.0 0.18 11.8 0.0 1.1 1 0 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) Redoxin PF08534.5 EWM20636.1 - 0.00032 20.2 0.1 0.00059 19.3 0.1 1.4 1 0 0 1 1 1 1 Redoxin DUF4656 PF15551.1 EWM20637.1 - 0.0057 15.9 2.7 0.0082 15.3 1.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4656) FYVE_2 PF02318.11 EWM20637.1 - 0.0086 15.9 4.1 0.013 15.3 2.9 1.2 1 0 0 1 1 1 1 FYVE-type zinc finger Rhodanese PF00581.15 EWM20637.1 - 0.032 14.5 0.0 0.052 13.9 0.0 1.4 1 0 0 1 1 1 0 Rhodanese-like domain FYVE PF01363.16 EWM20637.1 - 0.064 13.1 9.0 0.14 12.0 6.2 1.6 1 1 0 1 1 1 0 FYVE zinc finger C1_1 PF00130.17 EWM20637.1 - 1.5 8.5 7.6 0.55 9.9 1.5 2.6 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SR-25 PF10500.4 EWM20638.1 - 2.7 7.4 5.2 1.4 8.3 0.1 2.0 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein MA3 PF02847.12 EWM20639.1 - 4.2e-23 81.1 1.5 7.6e-23 80.3 1.0 1.4 1 0 0 1 1 1 1 MA3 domain Ctr PF04145.10 EWM20639.1 - 0.14 12.1 0.5 0.33 11.0 0.1 1.7 2 0 0 2 2 2 0 Ctr copper transporter family DDHD PF02862.12 EWM20639.1 - 0.34 10.6 9.1 0.29 10.8 3.7 2.2 2 0 0 2 2 2 0 DDHD domain SSP160 PF06933.6 EWM20639.1 - 7.8 4.3 25.8 9.4 4.0 17.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DEAD PF00270.24 EWM20640.1 - 1.4e-39 135.2 0.1 2e-39 134.7 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EWM20640.1 - 4.9e-25 87.1 0.5 1.3e-24 85.7 0.1 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EWM20640.1 - 0.0004 20.2 0.0 0.003 17.3 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EWM20640.1 - 0.0072 15.4 0.1 0.015 14.4 0.1 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit RINT1_TIP1 PF04437.8 EWM20640.1 - 0.051 12.1 0.1 0.071 11.6 0.1 1.1 1 0 0 1 1 1 0 RINT-1 / TIP-1 family Bestrophin PF01062.16 EWM20641.1 - 7.8e-10 38.1 0.1 1.1e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Mito_fiss_reg PF05308.6 EWM20642.1 - 0.46 9.8 5.1 0.67 9.2 3.5 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 EWM20642.1 - 0.69 9.1 2.7 0.93 8.7 1.9 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal NT5C PF06941.7 EWM20643.1 - 0.0026 17.2 0.0 0.0042 16.6 0.0 1.2 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) WGG PF10273.4 EWM20644.1 - 5.9e-19 67.9 0.0 9.2e-19 67.3 0.0 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Thioredoxin PF00085.15 EWM20645.1 - 1.3e-15 56.9 0.0 1.7e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 EWM20645.1 - 9.5e-07 28.7 0.0 2.1e-06 27.6 0.0 1.5 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_8 PF13905.1 EWM20645.1 - 3.6e-05 23.7 0.0 6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EWM20645.1 - 0.0013 18.8 0.0 0.0021 18.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EWM20645.1 - 0.067 12.8 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family DUF2847 PF11009.3 EWM20645.1 - 0.086 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) Bestrophin PF01062.16 EWM20646.1 - 2.7e-13 49.5 0.9 3.9e-13 49.0 0.6 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel RRM_2 PF04059.7 EWM20646.1 - 0.07 13.1 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif 2 DAO PF01266.19 EWM20647.1 - 0.026 13.4 0.0 0.036 12.9 0.0 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF3829 PF12889.2 EWM20647.1 - 0.077 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Glyco_transf_17 PF04724.8 EWM20648.1 - 4.5e-18 65.3 0.0 6.2e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 17 Glyco_transf_10 PF00852.14 EWM20649.1 - 2.4e-50 171.0 0.1 2.7e-50 170.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) DUF1640 PF07798.6 EWM20651.1 - 4.9e-06 26.7 4.2 8.4e-06 25.9 2.9 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) TBPIP PF07106.8 EWM20651.1 - 0.1 12.1 1.4 0.2 11.1 0.7 1.5 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Siah-Interact_N PF09032.6 EWM20651.1 - 0.15 12.1 1.7 0.3 11.1 0.6 2.0 1 1 1 2 2 2 0 Siah interacting protein, N terminal CopD PF05425.8 EWM20652.1 - 0.034 14.3 0.0 0.053 13.7 0.0 1.3 1 0 0 1 1 1 0 Copper resistance protein D DUF4635 PF15466.1 EWM20652.1 - 0.11 11.8 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) DUF3875 PF12991.2 EWM20653.1 - 0.059 13.0 0.1 14 5.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3875) E1-N PF14463.1 EWM20653.1 - 0.12 11.9 1.3 1.6 8.3 0.2 2.1 2 0 0 2 2 2 0 E1 N-terminal domain DivIC PF04977.10 EWM20653.1 - 1.4 8.4 5.0 0.65 9.5 1.2 2.1 2 0 0 2 2 2 0 Septum formation initiator IFP_35_N PF07334.8 EWM20653.1 - 7.9 6.5 10.4 11 6.0 0.9 3.0 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus PQQ_3 PF13570.1 EWM20654.1 - 0.0027 17.9 13.7 3 8.2 0.1 5.9 6 0 0 6 6 6 3 PQQ-like domain DEC-1_N PF04625.8 EWM20654.1 - 0.63 8.6 2.1 1.1 7.7 1.5 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region LVIVD PF08309.6 EWM20654.1 - 7.1 5.7 18.3 5 6.2 0.2 6.2 7 0 0 7 7 7 0 LVIVD repeat adh_short_C2 PF13561.1 EWM20657.1 - 1.4e-30 106.8 0.1 1.7e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EWM20657.1 - 1.1e-26 93.7 0.1 1.4e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EWM20657.1 - 2e-13 50.3 0.0 3.3e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Glyco_transf_4 PF13439.1 EWM20657.1 - 0.0061 16.3 0.1 0.64 9.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Shikimate_DH PF01488.15 EWM20657.1 - 0.043 13.9 0.2 0.074 13.1 0.2 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EWM20657.1 - 0.056 13.4 0.2 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 EWM20657.1 - 0.11 11.4 0.1 0.14 11.0 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EWM20657.1 - 0.12 11.1 0.1 0.15 10.6 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ecTbetaR2 PF08917.5 EWM20657.1 - 0.23 11.2 2.2 0.63 9.8 0.0 2.3 2 0 0 2 2 2 0 Transforming growth factor beta receptor 2 ectodomain DUF2665 PF11654.3 EWM20658.1 - 0.094 12.2 0.4 0.36 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2665) CTDII PF01556.13 EWM20659.1 - 2.2e-33 113.9 3.2 8.2e-22 76.9 0.1 3.3 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 EWM20659.1 - 2.7e-28 97.4 1.5 4.2e-28 96.8 1.1 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EWM20659.1 - 2.4e-15 56.3 18.8 4.7e-15 55.3 13.0 1.5 1 0 0 1 1 1 1 DnaJ central domain Sigma70_r4 PF04545.11 EWM20659.1 - 0.2 10.9 1.1 0.41 9.9 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 A2L_zn_ribbon PF08792.5 EWM20659.1 - 0.37 10.3 14.9 1.3 8.5 0.1 4.3 3 1 1 4 4 4 0 A2L zinc ribbon domain His_Phos_1 PF00300.17 EWM20660.1 - 2.9e-11 43.7 0.0 6.6e-11 42.5 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) zf-Tim10_DDP PF02953.10 EWM20661.1 - 1.9e-15 55.8 0.1 2.6e-15 55.4 0.1 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Topoisom_bac PF01131.15 EWM20663.1 - 4.3e-97 325.4 0.0 5.2e-97 325.2 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EWM20663.1 - 2.3e-11 43.5 0.0 4.8e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Toprim domain FXR1P_C PF12235.3 EWM20663.1 - 3.6 7.6 7.1 7.1 6.7 4.2 1.8 2 0 0 2 2 2 0 Fragile X-related 1 protein C terminal Popeye PF04831.8 EWM20664.1 - 6.2e-07 29.2 0.0 1.4e-06 28.1 0.0 1.6 1 1 0 1 1 1 1 Popeye protein conserved region cNMP_binding PF00027.24 EWM20664.1 - 3.3e-06 26.7 0.0 0.00022 20.9 0.0 2.8 2 1 0 2 2 2 1 Cyclic nucleotide-binding domain Mito_carr PF00153.22 EWM20665.1 - 1.7e-42 142.9 2.0 7.5e-16 57.6 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein CLN3 PF02487.12 EWM20665.1 - 0.0057 15.4 0.0 0.011 14.5 0.0 1.4 1 0 0 1 1 1 1 CLN3 protein Mito_carr PF00153.22 EWM20666.1 - 1.8e-42 142.9 2.0 7.4e-16 57.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein CLN3 PF02487.12 EWM20666.1 - 0.0057 15.4 0.0 0.011 14.5 0.0 1.4 1 0 0 1 1 1 1 CLN3 protein ABC2_membrane PF01061.19 EWM20670.1 - 2.8e-23 82.2 17.3 4.6e-23 81.4 12.0 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_2 PF12679.2 EWM20670.1 - 2.1e-08 33.3 7.6 3e-08 32.8 5.3 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_3 PF12698.2 EWM20670.1 - 7.9e-07 28.4 17.1 1.1e-06 27.9 11.8 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein PDR_CDR PF06422.7 EWM20670.1 - 0.0015 18.1 0.1 0.0084 15.7 0.0 2.3 2 0 0 2 2 2 1 CDR ABC transporter ABC2_membrane_4 PF12730.2 EWM20670.1 - 0.99 8.5 21.2 0.12 11.5 11.3 1.9 1 1 1 2 2 2 0 ABC-2 family transporter protein RAP1 PF07218.6 EWM20671.1 - 1.2 7.1 3.2 1.4 6.9 2.3 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF3661 PF12400.3 EWM20672.1 - 1.1e-23 83.7 5.4 2.8e-16 59.8 2.2 2.3 2 0 0 2 2 2 2 Vaculolar membrane protein ThiW PF09512.5 EWM20672.1 - 0.03 14.1 0.2 0.03 14.1 0.1 1.8 2 0 0 2 2 2 0 Thiamine-precursor transporter protein (ThiW) BAG PF02179.11 EWM20674.1 - 0.0036 17.3 0.1 0.0036 17.3 0.1 2.3 3 0 0 3 3 3 1 BAG domain Gon7 PF08738.5 EWM20674.1 - 0.16 11.9 7.1 2.3 8.2 0.6 2.8 3 0 0 3 3 3 0 Gon7 family DUF2205 PF10224.4 EWM20674.1 - 0.43 10.1 10.9 0.22 11.1 0.3 3.3 3 0 0 3 3 3 0 Predicted coiled-coil protein (DUF2205) Hydrolase PF00702.21 EWM20676.1 - 5.9e-14 53.0 0.0 2.2e-12 47.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EWM20676.1 - 1.5e-09 38.3 0.0 2.9e-09 37.3 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EWM20676.1 - 0.0026 17.4 1.3 0.0081 15.7 0.1 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase KaiC PF06745.8 EWM20676.1 - 0.064 12.3 0.0 0.093 11.8 0.0 1.2 1 0 0 1 1 1 0 KaiC FANCI_S1-cap PF14674.1 EWM20677.1 - 0.0025 17.8 1.8 0.45 10.5 0.0 3.1 3 0 0 3 3 3 2 FANCI solenoid 1 cap C2 PF00168.25 EWM20678.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 C2 domain RNase_PH PF01138.16 EWM20680.1 - 4.2e-19 69.1 0.0 6.3e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EWM20680.1 - 0.00014 21.6 0.0 0.00035 20.4 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 adh_short PF00106.20 EWM20681.1 - 8e-18 64.9 2.2 1.3e-17 64.2 0.6 2.0 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EWM20681.1 - 7.9e-06 25.6 0.0 1.7e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EWM20681.1 - 0.00012 21.9 0.0 0.00021 21.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1764 PF08576.5 EWM20684.1 - 1.6e-16 60.9 3.0 2.4e-16 60.3 0.1 2.0 1 1 1 2 2 2 1 Eukaryotic protein of unknown function (DUF1764) zf-UBP PF02148.14 EWM20686.1 - 5.2e-16 58.5 7.5 1.6e-15 56.9 5.2 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein BRAP2 PF07576.7 EWM20686.1 - 1.3e-09 37.5 0.0 4.9e-09 35.7 0.0 1.9 3 0 0 3 3 3 1 BRCA1-associated protein 2 zf-rbx1 PF12678.2 EWM20686.1 - 2e-05 24.5 0.0 2e-05 24.5 0.0 1.9 2 0 0 2 2 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EWM20686.1 - 4.9e-05 22.9 1.2 4.9e-05 22.9 0.8 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 EWM20686.1 - 0.0004 20.1 4.0 0.0004 20.1 2.8 2.3 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.20 EWM20686.1 - 0.024 14.2 3.1 0.094 12.3 2.3 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ArfGap PF01412.13 EWM20686.1 - 0.35 10.6 2.4 1.1 9.0 1.7 1.8 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf Filament PF00038.16 EWM20686.1 - 0.36 10.2 8.1 1 8.7 5.6 1.7 1 1 0 1 1 1 0 Intermediate filament protein ALIX_LYPXL_bnd PF13949.1 EWM20686.1 - 0.49 9.3 6.9 0.77 8.6 4.8 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV IncA PF04156.9 EWM20686.1 - 1.3 8.5 8.3 2.4 7.6 5.4 1.6 1 1 0 1 1 1 0 IncA protein zf-C3HC4_2 PF13923.1 EWM20686.1 - 6.3 6.9 12.1 0.19 11.7 1.6 3.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RVT_2 PF07727.9 EWM20690.1 - 1.5e-83 279.5 0.0 2.2e-83 279.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 EWM20690.1 - 0.079 12.9 16.3 0.051 13.5 3.2 3.1 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 EWM20690.1 - 0.9 9.2 10.0 1.1 9.0 0.4 3.2 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_5 PF14787.1 EWM20690.1 - 3.9 7.0 14.8 3.4 7.2 2.6 2.7 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.1 EWM20690.1 - 4 7.2 11.2 1.6 8.4 2.5 2.7 2 0 0 2 2 2 0 Zinc knuckle NTPase_I-T PF01931.13 EWM20694.1 - 1.4e-32 112.7 0.0 1.6e-17 63.7 0.0 2.4 2 1 0 2 2 2 2 Protein of unknown function DUF84 PNMA PF14893.1 EWM20694.1 - 0.02 13.9 0.2 0.029 13.4 0.1 1.2 1 0 0 1 1 1 0 PNMA Thioredoxin PF00085.15 EWM20695.1 - 4.3e-05 23.1 0.0 6.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 EWM20695.1 - 0.1 12.6 0.0 0.38 10.8 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like PepSY_TM PF03929.11 EWM20695.1 - 0.35 11.3 2.5 1 9.8 1.7 1.8 1 0 0 1 1 1 0 PepSY-associated TM helix WD40 PF00400.27 EWM20698.1 - 3.1e-16 58.5 6.0 4.3e-08 32.7 0.8 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Ferritin PF00210.19 EWM20700.1 - 2.6e-20 72.6 0.4 9.1e-20 70.8 0.3 1.7 1 1 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.12 EWM20700.1 - 0.0048 17.2 1.0 0.27 11.5 0.0 2.2 2 0 0 2 2 2 2 Rubrerythrin THOC7 PF05615.8 EWM20702.1 - 0.0041 17.4 5.1 0.0051 17.0 3.5 1.1 1 0 0 1 1 1 1 Tho complex subunit 7 Mucin PF01456.12 EWM20702.1 - 0.087 12.5 5.7 0.33 10.7 3.9 1.9 1 1 0 1 1 1 0 Mucin-like glycoprotein DUF3584 PF12128.3 EWM20702.1 - 0.12 9.6 11.2 0.13 9.5 7.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PAT1 PF09770.4 EWM20702.1 - 0.57 8.3 14.7 0.7 8.0 10.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FAP PF07174.6 EWM20702.1 - 1.7 7.8 24.5 4.1 6.6 17.0 1.6 1 1 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF3347 PF11827.3 EWM20702.1 - 5.4 6.9 9.9 7.3 6.5 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) GRA6 PF05084.8 EWM20702.1 - 6.2 6.2 9.5 11 5.4 6.4 1.7 1 1 0 1 1 1 0 Granule antigen protein (GRA6) APG6 PF04111.7 EWM20702.1 - 8 5.4 9.5 10 5.0 6.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 SpoIIIAH PF12685.2 EWM20702.1 - 9.6 5.6 13.8 24 4.3 9.6 1.6 1 1 0 1 1 1 0 SpoIIIAH-like protein DUF2752 PF10825.3 EWM20703.1 - 0.033 14.1 0.0 0.076 13.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) ATP_bind_3 PF01171.15 EWM20706.1 - 3.5e-20 72.2 0.0 3.9e-20 72.1 0.0 1.0 1 0 0 1 1 1 1 PP-loop family QueC PF06508.8 EWM20706.1 - 0.016 14.4 0.0 0.14 11.4 0.0 1.9 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Lar_restr_allev PF14354.1 EWM20707.1 - 0.096 13.0 0.0 0.24 11.7 0.0 1.7 1 1 0 1 1 1 0 Restriction alleviation protein Lar Prim_Zn_Ribbon PF08273.7 EWM20707.1 - 0.4 10.7 2.5 1.2 9.2 0.2 2.5 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Ammonium_transp PF00909.16 EWM20709.1 - 4.2e-07 28.7 7.9 6e-07 28.2 5.5 1.2 1 0 0 1 1 1 1 Ammonium Transporter Family NADHdh-2_N PF12155.3 EWM20709.1 - 0.055 13.6 3.6 3.3 7.9 0.1 3.2 2 2 0 2 2 2 0 NADH dehydrogenase subunit 2 N-terminal DUF805 PF05656.9 EWM20709.1 - 0.19 11.5 0.0 0.19 11.5 0.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF805) Rhodanese PF00581.15 EWM20710.1 - 2.8e-09 37.3 0.0 7e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain Methyltransf_16 PF10294.4 EWM20711.1 - 0.00076 18.9 0.0 0.00097 18.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Abhydrolase_5 PF12695.2 EWM20712.1 - 0.00064 19.4 0.1 0.0018 18.0 0.0 1.7 2 1 1 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EWM20712.1 - 0.012 15.4 1.3 0.024 14.5 0.9 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EWM20712.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EWM20714.1 - 0.15 11.9 0.0 0.27 11.0 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family PP-binding PF00550.20 EWM20716.1 - 2.4e-10 40.5 0.3 3.3e-10 40.0 0.2 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EWM20716.1 - 0.04 13.9 0.5 0.048 13.6 0.3 1.3 1 0 0 1 1 1 0 Acyl-carrier Pheromone PF08015.6 EWM20718.1 - 1.5 9.7 6.7 10 7.0 0.5 2.9 3 0 0 3 3 3 0 Fungal mating-type pheromone cNMP_binding PF00027.24 EWM20719.1 - 1.8e-09 37.3 0.0 6.9e-09 35.4 0.0 2.0 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Cupin_2 PF07883.6 EWM20719.1 - 0.0015 17.9 0.0 0.004 16.6 0.0 1.7 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 EWM20719.1 - 0.018 14.4 0.0 0.044 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) AOX PF01786.12 EWM20720.1 - 1.7e-12 47.2 0.0 1.9e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase HTH_Tnp_Tc5 PF03221.11 EWM20720.1 - 0.07 12.9 0.1 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain Amidase PF01425.16 EWM20721.1 - 3.8e-08 32.6 0.0 4.7e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Amidase Mito_fiss_reg PF05308.6 EWM20722.1 - 8 5.7 7.7 10 5.3 5.4 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator AOX PF01786.12 EWM20723.1 - 2e-18 66.5 0.2 3e-18 65.9 0.1 1.2 1 0 0 1 1 1 1 Alternative oxidase Drc1-Sld2 PF11719.3 EWM20723.1 - 0.045 12.8 0.0 0.053 12.5 0.0 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein Ribosomal_60s PF00428.14 EWM20723.1 - 0.65 10.4 5.1 1.1 9.7 3.5 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Pkinase PF00069.20 EWM20724.1 - 4.6e-38 130.8 0.0 6.1e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM20724.1 - 4.4e-16 58.7 0.0 2.7e-14 52.8 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EWM20724.1 - 6.2e-05 22.0 0.0 8.8e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EWM20724.1 - 0.031 14.0 0.8 0.055 13.2 0.5 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EWM20724.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EWM20725.1 - 2.4e-33 115.4 0.0 3.1e-33 115.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM20725.1 - 1.6e-14 53.6 0.0 2.1e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EWM20725.1 - 3.3e-05 23.0 0.0 4.2e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EWM20725.1 - 0.016 14.9 1.0 0.028 14.1 0.3 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EWM20725.1 - 0.076 12.0 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Helicase_C PF00271.26 EWM20730.1 - 5.2e-11 42.2 0.0 1.8e-10 40.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EWM20730.1 - 7.7e-07 28.7 0.1 2e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase HA2 PF04408.18 EWM20730.1 - 2.1e-05 24.4 0.0 4.9e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) AAA_22 PF13401.1 EWM20730.1 - 0.00012 22.2 0.0 0.00061 19.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EWM20730.1 - 0.0011 18.6 0.5 0.003 17.2 0.3 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EWM20730.1 - 0.017 14.7 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Daxx PF03344.10 EWM20733.1 - 0.66 8.3 8.7 0.79 8.1 6.0 1.0 1 0 0 1 1 1 0 Daxx Family DUF21 PF01595.15 EWM20734.1 - 4e-27 94.6 1.4 4e-27 94.6 1.0 2.2 3 0 0 3 3 3 1 Domain of unknown function DUF21 CBS PF00571.23 EWM20734.1 - 0.022 14.5 0.0 13 5.6 0.0 3.3 2 1 0 2 2 2 0 CBS domain PLDc_N PF13396.1 EWM20734.1 - 0.062 12.9 0.5 0.14 11.8 0.4 1.6 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal DUF21 PF01595.15 EWM20735.1 - 5.5e-12 45.3 2.7 8.4e-12 44.7 1.8 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 WD40 PF00400.27 EWM20739.1 - 3.2e-09 36.3 1.1 0.00062 19.5 0.0 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat HlyIII PF03006.15 EWM20740.1 - 2.3e-11 43.5 9.1 4.4e-11 42.6 6.3 1.4 1 0 0 1 1 1 1 Haemolysin-III related HNH PF01844.18 EWM20742.1 - 0.0018 18.0 6.0 0.0073 16.1 2.5 2.4 2 0 0 2 2 2 1 HNH endonuclease Zn_clus PF00172.13 EWM20744.1 - 1.4e-05 24.9 7.9 3.8e-05 23.4 5.5 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAP_fibrillin PF04755.7 EWM20745.1 - 2.9e-19 69.5 0.4 2.4e-15 56.7 0.0 2.1 1 1 1 2 2 2 2 PAP_fibrillin UPF0118 PF01594.11 EWM20746.1 - 6.5e-29 100.9 9.1 7.5e-29 100.7 6.3 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF20 HCV_NS1 PF01560.12 EWM20748.1 - 0.11 10.9 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein E2/NS1 HAD_2 PF13419.1 EWM20750.1 - 1.5e-09 38.3 0.0 9.2e-09 35.7 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EWM20750.1 - 7.2e-06 25.6 0.2 1.3e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like DUF3339 PF11820.3 EWM20750.1 - 0.068 13.4 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3339) Hydrolase PF00702.21 EWM20750.1 - 0.11 12.8 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Activator_LAG-3 PF11498.3 EWM20756.1 - 0.016 13.9 22.6 0.017 13.8 15.7 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Pex14_N PF04695.8 EWM20756.1 - 0.54 10.3 8.2 0.62 10.0 5.7 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region BAF1_ABF1 PF04684.8 EWM20756.1 - 1.2 7.8 21.3 1.4 7.7 14.8 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PAT1 PF09770.4 EWM20756.1 - 6 4.9 16.3 6.5 4.8 11.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GST_N_3 PF13417.1 EWM20757.1 - 3.4e-10 40.0 0.1 8.1e-08 32.3 0.0 3.1 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EWM20757.1 - 9.4e-05 22.3 0.2 0.0015 18.4 0.0 2.6 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain COPR5 PF15340.1 EWM20758.1 - 0.88 9.9 3.6 0.55 10.5 1.0 1.7 1 1 1 2 2 2 0 Cooperator of PRMT5 family COPR5 PF15340.1 EWM20759.1 - 0.88 9.9 3.6 0.55 10.5 1.0 1.7 1 1 1 2 2 2 0 Cooperator of PRMT5 family AMP-binding PF00501.23 EWM20762.1 - 7.1e-90 301.3 0.0 1e-89 300.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EWM20762.1 - 1.5e-20 73.9 0.0 3.3e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 EWM20763.1 - 9.2e-64 215.3 0.0 1.3e-63 214.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Cellulase PF00150.13 EWM20764.1 - 9.1e-08 31.6 0.0 1.1e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PC-Esterase PF13839.1 EWM20765.1 - 1.2e-05 25.3 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Sperm_Ag_HE2 PF05324.8 EWM20765.1 - 0.056 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Sperm antigen HE2 HSP70 PF00012.15 EWM20768.1 - 1.4e-36 125.6 6.6 1.8e-29 102.1 0.1 3.0 3 0 0 3 3 3 2 Hsp70 protein CCDC-167 PF15188.1 EWM20768.1 - 1.1 9.2 11.1 2.2 8.2 3.7 2.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 HSP70 PF00012.15 EWM20769.1 - 1.4e-36 125.6 6.7 1.7e-29 102.2 0.1 3.0 3 0 0 3 3 3 2 Hsp70 protein CCDC-167 PF15188.1 EWM20769.1 - 0.82 9.6 5.4 2.1 8.3 3.7 1.7 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Glyco_hydro_44 PF12891.2 EWM20771.1 - 0.028 13.9 0.1 0.046 13.2 0.1 1.3 1 0 0 1 1 1 0 Glycoside hydrolase family 44 IncA PF04156.9 EWM20771.1 - 1.1 8.8 5.0 1.6 8.2 3.5 1.2 1 0 0 1 1 1 0 IncA protein Galactosyl_T PF01762.16 EWM20772.1 - 1.1e-09 38.2 0.0 2.1e-09 37.2 0.0 1.5 1 1 0 1 1 1 1 Galactosyltransferase Methyltransf_21 PF05050.7 EWM20773.1 - 8.2e-11 42.1 0.0 1.3e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_22 PF13383.1 EWM20773.1 - 0.0001 21.9 0.0 0.0002 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain B3 PF02362.16 EWM20773.1 - 0.0014 18.2 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 B3 DNA binding domain HSP70 PF00012.15 EWM20774.1 - 3.6e-36 124.2 0.0 4.5e-36 123.9 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EWM20774.1 - 0.004 15.8 0.7 0.0075 14.8 0.0 1.7 3 0 0 3 3 3 1 MreB/Mbl protein RVT_2 PF07727.9 EWM20777.1 - 1.3e-52 178.2 0.0 2.2e-52 177.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 EWM20779.1 - 1.3e-83 279.7 0.0 1.9e-83 279.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3213 PF11491.3 EWM20779.1 - 0.022 14.6 0.0 5.8 6.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3213) RCC1 PF00415.13 EWM20781.1 - 5.2e-64 212.2 24.8 1.2e-11 44.5 0.0 7.7 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EWM20781.1 - 1.1e-37 126.7 30.4 8.5e-08 31.6 1.5 7.2 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Kelch_6 PF13964.1 EWM20781.1 - 0.012 15.7 1.2 1.4 9.2 0.1 3.6 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.10 EWM20781.1 - 0.016 14.9 0.6 6.9 6.6 0.1 3.8 3 0 0 3 3 3 0 Kelch motif CBM_X PF06204.6 EWM20781.1 - 2.2 7.8 8.3 13 5.3 0.1 3.6 3 0 0 3 3 3 0 Putative carbohydrate binding domain GRP PF07172.6 EWM20782.1 - 0.014 15.8 5.9 0.024 15.0 4.1 1.3 1 0 0 1 1 1 0 Glycine rich protein family DIOX_N PF14226.1 EWM20785.1 - 1.9e-31 109.0 0.0 2.9e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EWM20785.1 - 1.5e-17 63.6 0.0 2.9e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EWM20786.1 - 1.7e-17 63.5 0.0 3.4e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EWM20786.1 - 2.3e-13 50.6 0.1 3.8e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal NuA4 PF09340.5 EWM20787.1 - 0.17 11.5 0.0 22 4.7 0.0 2.4 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 XRN_N PF03159.13 EWM20789.1 - 0.0019 17.5 0.0 0.0026 17.2 0.0 1.1 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus V-ATPase_H_N PF03224.9 EWM20792.1 - 0.00035 19.7 0.0 0.00037 19.7 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_N PF03224.9 EWM20794.1 - 2.4e-06 26.8 0.0 2.8e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 V-ATPase subunit H DUF4470 PF14737.1 EWM20794.1 - 0.14 11.8 0.1 0.32 10.7 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4470) DUF3815 PF12821.2 EWM20795.1 - 2e-13 50.4 13.2 2e-13 50.4 9.2 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) Herpes_LAMP2 PF06126.6 EWM20795.1 - 0.13 10.6 5.1 0.15 10.4 3.5 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 Pribosyltran PF00156.22 EWM20796.1 - 2.4e-15 56.3 0.0 4.8e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EWM20796.1 - 0.056 12.6 0.0 0.092 11.9 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase DUF1212 PF06738.7 EWM20797.1 - 1.4e-29 102.9 13.9 1.1e-28 100.0 0.3 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EWM20797.1 - 5.2e-16 58.7 27.3 1.6e-14 53.9 7.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3815) Mso1_Sec1_bdg PF14475.1 EWM20799.1 - 0.52 9.7 6.4 58 3.1 0.1 4.4 2 2 3 5 5 5 0 Sec1-binding region of Mso1 Prefoldin PF02996.12 EWM20801.1 - 9.1e-26 89.8 0.4 1.5e-25 89.1 0.1 1.5 1 1 0 1 1 1 1 Prefoldin subunit DASH_Dad2 PF08654.5 EWM20801.1 - 0.0012 18.7 3.8 0.0017 18.3 0.3 2.1 2 0 0 2 2 2 1 DASH complex subunit Dad2 Prefoldin_2 PF01920.15 EWM20801.1 - 0.0016 18.1 3.8 0.055 13.2 0.4 2.3 2 0 0 2 2 2 2 Prefoldin subunit Spc7 PF08317.6 EWM20801.1 - 0.017 13.7 3.7 0.97 8.0 0.2 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Spectrin PF00435.16 EWM20801.1 - 0.033 14.4 0.3 6.2 7.1 0.0 2.2 2 0 0 2 2 2 0 Spectrin repeat Serine_rich PF08824.5 EWM20801.1 - 0.047 13.4 0.2 0.32 10.7 0.0 2.0 2 0 0 2 2 2 0 Serine rich protein interaction domain Prefoldin_3 PF13758.1 EWM20801.1 - 0.057 13.1 0.2 0.14 11.9 0.1 1.8 1 1 0 1 1 1 0 Prefoldin subunit TMF_TATA_bd PF12325.3 EWM20801.1 - 0.077 12.7 0.4 0.077 12.7 0.3 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding SYCE1 PF15233.1 EWM20801.1 - 0.09 12.7 3.7 1.6 8.6 0.1 2.1 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 Cortex-I_coil PF09304.5 EWM20801.1 - 0.14 12.1 4.3 0.5 10.4 0.2 2.3 2 0 0 2 2 2 0 Cortexillin I, coiled coil GAS PF13851.1 EWM20801.1 - 0.23 10.6 4.4 0.44 9.7 0.1 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding K-box PF01486.12 EWM20801.1 - 0.24 11.2 4.0 0.77 9.5 0.1 2.5 2 1 0 2 2 2 0 K-box region ING PF12998.2 EWM20801.1 - 0.31 11.3 2.8 0.92 9.8 0.2 2.3 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding SlyX PF04102.7 EWM20801.1 - 6.1 7.3 5.8 4.5 7.7 0.1 2.4 2 1 0 2 2 2 0 SlyX Rubredoxin PF00301.15 EWM20802.1 - 5.4e-07 29.3 4.8 8.3e-07 28.7 3.4 1.3 1 0 0 1 1 1 1 Rubredoxin ADK_lid PF05191.9 EWM20802.1 - 0.038 13.6 1.1 0.071 12.7 0.8 1.4 1 1 0 1 1 1 0 Adenylate kinase, active site lid Zn_Tnp_IS1595 PF12760.2 EWM20802.1 - 0.068 12.9 2.2 4.1 7.2 0.2 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-RanBP PF00641.13 EWM20802.1 - 0.16 11.0 3.0 1.7 7.8 0.1 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others TF_Zn_Ribbon PF08271.7 EWM20802.1 - 0.56 9.5 6.4 0.83 9.0 0.4 2.5 1 1 0 2 2 2 0 TFIIB zinc-binding PhnA_Zn_Ribbon PF08274.7 EWM20802.1 - 1.2 9.0 3.9 20 5.0 0.1 2.3 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-ribbon_3 PF13248.1 EWM20802.1 - 1.2 8.4 4.5 14 5.0 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain PHD_2 PF13831.1 EWM20802.1 - 3.8 6.9 5.9 3.6 6.9 0.2 2.2 2 0 0 2 2 2 0 PHD-finger zf-C2H2 PF00096.21 EWM20802.1 - 4.5 7.8 5.0 36 4.9 0.4 2.8 2 1 0 2 2 2 0 Zinc finger, C2H2 type UPF0547 PF10571.4 EWM20802.1 - 5.6 6.7 6.4 26 4.6 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Med13_N PF11597.3 EWM20803.1 - 0.019 13.6 0.0 0.022 13.4 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal XRN_N PF03159.13 EWM20808.1 - 9.5e-20 70.9 0.7 1e-19 70.8 0.0 1.3 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus Isochorismatase PF00857.15 EWM20811.1 - 5.6e-07 29.6 0.1 1.1e-06 28.7 0.1 1.4 1 0 0 1 1 1 1 Isochorismatase family LSM PF01423.17 EWM20813.1 - 6.1e-12 44.9 0.6 7.7e-12 44.5 0.4 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EWM20813.1 - 0.021 14.7 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Peptidase_C12 PF01088.16 EWM20814.1 - 4.4e-21 75.0 0.0 4.7e-21 74.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Gp37 PF09646.5 EWM20815.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Gp37 protein DUF2346 PF09803.4 EWM20818.1 - 0.0009 19.0 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) Thr_dehydrat_C PF00585.13 EWM20818.1 - 0.14 11.8 0.1 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 C-terminal regulatory domain of Threonine dehydratase FMN_dh PF01070.13 EWM20821.1 - 5e-80 269.0 0.0 6.6e-80 268.6 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase TMP-TENI PF02581.12 EWM20821.1 - 0.0047 16.0 0.7 1.8 7.6 0.0 2.2 2 0 0 2 2 2 2 Thiamine monophosphate synthase/TENI Polyketide_cyc2 PF10604.4 EWM20823.1 - 0.015 15.4 0.2 0.017 15.2 0.1 1.1 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport DHDPS PF00701.17 EWM20824.1 - 7.3e-38 129.8 0.0 1.3e-37 129.0 0.0 1.4 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family zf-rbx1 PF12678.2 EWM20825.1 - 6.7e-27 93.3 8.4 8.3e-27 93.1 5.8 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EWM20825.1 - 1.2e-14 53.8 6.1 2e-14 53.2 4.2 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EWM20825.1 - 1.5e-09 37.5 8.4 6.2e-09 35.5 5.8 1.9 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EWM20825.1 - 7.5e-07 29.0 7.9 1.7e-06 27.9 2.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EWM20825.1 - 1e-06 28.2 3.8 2.1e-06 27.2 2.6 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EWM20825.1 - 1.9e-06 27.5 4.8 3.5e-06 26.6 3.3 1.5 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EWM20825.1 - 0.00045 19.8 8.7 0.0022 17.6 6.0 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 EWM20825.1 - 0.0087 15.5 2.2 0.014 14.8 1.5 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.2 EWM20825.1 - 0.02 14.9 6.5 0.13 12.3 4.5 2.1 1 1 0 1 1 1 0 RING-variant domain zf-RING_UBOX PF13445.1 EWM20825.1 - 0.079 12.6 3.9 0.51 10.1 2.7 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EWM20825.1 - 0.54 10.1 7.9 1.9 8.4 2.7 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EWM20825.1 - 1 9.2 5.4 0.18 11.5 0.4 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein ABC_ATPase PF09818.4 EWM20827.1 - 2.4e-110 369.1 0.0 3.6e-110 368.6 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_25 PF13481.1 EWM20827.1 - 0.0058 16.0 0.0 0.037 13.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EWM20827.1 - 0.046 13.1 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.1 EWM20827.1 - 0.09 13.0 0.1 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1485 PF07364.7 EWM20827.1 - 0.096 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1485) ABC_ATPase PF09818.4 EWM20828.1 - 1.3e-38 132.8 0.1 2e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 Predicted ATPase of the ABC class DUF1485 PF07364.7 EWM20828.1 - 0.1 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1485) Zn_clus PF00172.13 EWM20829.1 - 1.7e-07 31.0 11.8 2.8e-07 30.3 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 EWM20830.1 - 1.7e-07 31.0 11.8 2.8e-07 30.3 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 EWM20831.1 - 1.6e-07 31.1 11.8 2.5e-07 30.4 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 EWM20832.1 - 2e-75 253.3 0.0 2.7e-75 252.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM20832.1 - 3.4e-33 114.8 0.0 4.4e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EWM20832.1 - 2.9e-07 29.7 0.1 4.5e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EWM20832.1 - 0.001 18.0 0.0 0.0017 17.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 EWM20832.1 - 0.0039 16.0 0.0 0.0059 15.4 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.18 EWM20832.1 - 0.01 15.6 0.1 0.54 9.9 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 EWM20832.1 - 0.05 12.9 0.4 0.14 11.4 0.2 1.6 1 1 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 EWM20832.1 - 0.076 12.5 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF3432 PF11914.3 EWM20833.1 - 0.052 13.5 1.4 0.15 12.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3432) Gly-zipper_Omp PF13488.1 EWM20835.1 - 7.7e-08 31.8 45.0 79 3.0 31.3 2.5 1 1 0 1 1 1 0 Glycine zipper Gly-zipper_YMGG PF13441.1 EWM20835.1 - 2.2e-07 30.2 40.4 0.0002 20.8 15.9 2.3 1 1 1 2 2 2 2 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.1 EWM20835.1 - 4.5e-06 26.3 32.3 0.0011 18.6 12.2 2.3 1 1 1 2 2 2 2 Glycine-zipper containing OmpA-like membrane domain DUF456 PF04306.8 EWM20835.1 - 7.1e-06 26.0 29.8 0.0015 18.6 7.8 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF456) Rick_17kDa_Anti PF05433.10 EWM20835.1 - 0.019 14.5 55.2 1.5e+04 -14.6 38.1 4.5 1 1 0 1 1 1 0 Glycine zipper 2TM domain Yae1_N PF09811.4 EWM20835.1 - 1.2 8.7 5.3 31 4.1 0.0 3.9 2 1 3 5 5 5 0 Essential protein Yae1, N terminal Bacteriocin_IIc PF10439.4 EWM20835.1 - 1.7 8.8 46.1 1.5e+04 -14.1 32.0 3.1 1 1 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Romo1 PF10247.4 EWM20835.1 - 2.7 8.2 44.6 1.5e+04 -24.8 30.9 4.5 1 1 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 DUF1269 PF06897.7 EWM20835.1 - 5.4 7.0 27.8 63 3.6 9.4 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1269) SBBP PF06739.6 EWM20836.1 - 7.3e-08 32.0 30.3 0.00049 19.8 0.7 4.2 5 0 0 5 5 5 3 Beta-propeller repeat Aft1_OSA PF11785.3 EWM20836.1 - 0.02 15.4 0.0 11 6.5 0.0 3.3 3 0 0 3 3 3 0 Aft1 osmotic stress response (OSM) domain GCV_H PF01597.14 EWM20836.1 - 0.023 14.3 0.1 3.6 7.2 0.0 3.2 4 0 0 4 4 4 0 Glycine cleavage H-protein DUF1593 PF07632.6 EWM20836.1 - 0.1 11.9 1.1 13 5.0 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1593) Alpha_adaptinC2 PF02883.15 EWM20839.1 - 0.16 12.3 0.0 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 Adaptin C-terminal domain SBBP PF06739.6 EWM20839.1 - 0.18 11.6 13.1 0.18 11.6 0.7 3.2 3 0 0 3 3 3 0 Beta-propeller repeat PT PF04886.7 EWM20839.1 - 0.88 8.9 36.2 0.021 14.1 13.2 3.1 3 0 0 3 3 3 0 PT repeat RVT_2 PF07727.9 EWM20840.1 - 9.3e-84 280.2 0.0 1.7e-83 279.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EWM20840.1 - 3.3e-22 78.8 0.0 8.2e-22 77.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EWM20840.1 - 1.5e-09 37.3 0.0 4.6e-09 35.7 0.0 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 EWM20840.1 - 0.026 14.0 0.0 0.067 12.7 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Cas_Csa5 PF09702.5 EWM20840.1 - 0.029 14.4 0.2 5.2 7.1 0.0 2.9 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csa5) Hist_deacetyl PF00850.14 EWM20846.1 - 0.00069 18.9 0.0 0.0015 17.8 0.0 1.6 2 1 0 2 2 2 1 Histone deacetylase domain Sugar_tr PF00083.19 EWM20847.1 - 2.3e-09 36.3 0.4 2.3e-09 36.3 0.3 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 EWM20847.1 - 6.5e-09 34.9 10.1 5.4e-06 25.3 5.8 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily FTR1 PF03239.9 EWM20847.1 - 0.064 12.2 0.0 0.19 10.6 0.0 1.4 1 1 0 1 1 1 0 Iron permease FTR1 family Treslin_N PF15292.1 EWM20848.1 - 0.035 12.0 0.1 0.037 11.9 0.0 1.0 1 0 0 1 1 1 0 Treslin N-terminus IQ PF00612.22 EWM20849.1 - 0.015 14.8 0.6 0.03 13.9 0.4 1.5 1 0 0 1 1 1 0 IQ calmodulin-binding motif DAHP_synth_1 PF00793.15 EWM20849.1 - 0.096 11.3 0.0 0.11 11.1 0.0 1.0 1 0 0 1 1 1 0 DAHP synthetase I family DUF4031 PF13223.1 EWM20849.1 - 0.14 12.2 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4031) Cyclin PF08613.6 EWM20851.1 - 2.7e-19 70.0 0.0 4.1e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EWM20851.1 - 4.4e-06 26.2 0.0 6.3e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain PTH2 PF01981.11 EWM20852.1 - 8.1e-41 138.3 0.0 1.1e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 PTH2 PF01981.11 EWM20853.1 - 5.3e-14 51.9 0.1 7.8e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 AhpC-TSA PF00578.16 EWM20854.1 - 1.3e-26 92.6 0.0 3.6e-26 91.2 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 EWM20854.1 - 7.9e-10 38.2 0.0 1.4e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 EWM20854.1 - 1.9e-08 33.9 0.0 4e-08 32.9 0.0 1.5 1 1 0 1 1 1 1 Redoxin Sex_peptide PF08138.6 EWM20856.1 - 0.082 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Sex peptide (SP) family Glyco_transf_92 PF01697.22 EWM20857.1 - 4.6e-11 42.5 0.0 7.8e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.1 EWM20857.1 - 0.01 16.1 0.1 0.061 13.6 0.0 2.2 1 1 0 1 1 1 0 Glycosyl transferase family 2 Glyco_transf_92 PF01697.22 EWM20858.1 - 2.3e-12 46.8 0.0 5.1e-12 45.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.1 EWM20858.1 - 0.016 15.5 0.1 0.096 13.0 0.0 2.3 1 1 0 1 1 1 0 Glycosyl transferase family 2 Glyco_transf_92 PF01697.22 EWM20859.1 - 8.1e-11 41.7 0.0 1.3e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.1 EWM20859.1 - 0.0092 16.2 0.0 0.054 13.8 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.22 EWM20860.1 - 1.5e-11 44.1 0.0 3.2e-11 43.0 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.1 EWM20860.1 - 0.017 15.3 0.1 0.096 13.0 0.0 2.2 1 1 0 1 1 1 0 Glycosyl transferase family 2 Glyco_transf_92 PF01697.22 EWM20863.1 - 5.5e-12 45.5 0.0 1e-11 44.6 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.1 EWM20863.1 - 0.049 13.9 0.1 0.27 11.5 0.0 2.2 1 1 0 1 1 1 0 Glycosyl transferase family 2 Glyco_transf_92 PF01697.22 EWM20864.1 - 4e-12 46.0 0.0 8.1e-12 45.0 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.1 EWM20864.1 - 0.0049 17.1 0.0 0.026 14.8 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 2 HAT PF02184.11 EWM20866.1 - 0.0001 21.9 0.3 0.031 14.0 0.2 3.3 3 0 0 3 3 3 1 HAT (Half-A-TPR) repeat Suf PF05843.9 EWM20866.1 - 0.00045 20.0 0.0 11 5.6 0.0 3.7 4 0 0 4 4 4 3 Suppressor of forked protein (Suf) TPR_16 PF13432.1 EWM20866.1 - 0.0072 16.9 5.8 0.081 13.6 0.0 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat Glyco_hydro_47 PF01532.15 EWM20866.1 - 0.25 9.9 0.8 0.38 9.3 0.1 1.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 47 TPR_14 PF13428.1 EWM20866.1 - 0.68 10.7 13.8 1.7 9.4 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EWM20867.1 - 6.2e-31 104.7 8.1 1.2e-06 27.8 0.1 5.6 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.1 EWM20867.1 - 2.8e-30 103.7 18.1 1.6e-11 43.7 0.4 4.4 4 0 0 4 4 4 4 TPR repeat TPR_2 PF07719.12 EWM20867.1 - 5.6e-29 97.7 12.1 3.8e-07 29.5 0.6 5.8 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_17 PF13431.1 EWM20867.1 - 4.9e-23 79.3 12.3 2.1e-05 24.3 0.0 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 EWM20867.1 - 8.6e-23 80.4 17.0 1.1e-09 38.7 1.4 4.3 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 EWM20867.1 - 5.8e-19 66.8 10.9 1.2e-05 25.5 0.2 5.7 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 EWM20867.1 - 1.1e-18 66.8 8.8 1.8e-07 31.0 0.0 4.0 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EWM20867.1 - 1.4e-17 62.0 4.0 0.0011 18.5 0.5 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_6 PF13174.1 EWM20867.1 - 2.5e-12 46.3 10.1 0.00012 22.2 0.3 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 EWM20867.1 - 8.8e-11 40.7 8.1 0.012 15.3 0.2 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 EWM20867.1 - 2.3e-08 33.7 4.7 0.00018 21.2 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EWM20867.1 - 2.8e-07 30.7 10.2 0.068 13.5 0.4 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 EWM20867.1 - 2.2e-06 27.4 16.1 0.088 12.7 0.1 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_15 PF13429.1 EWM20867.1 - 0.002 17.2 0.3 0.37 9.7 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EWM20867.1 - 0.026 14.6 2.2 29 4.9 0.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.4 EWM20867.1 - 0.077 12.3 1.2 2 7.7 0.0 2.8 3 0 0 3 3 3 0 26S proteasome subunit RPN7 TPR_4 PF07721.9 EWM20867.1 - 0.13 12.7 14.8 1.6 9.3 0.1 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_21 PF09976.4 EWM20867.1 - 1.6 8.7 9.0 0.13 12.2 1.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 EWM20867.1 - 7.1 6.6 8.5 31 4.5 0.0 3.9 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain HAT PF02184.11 EWM20868.1 - 6e-11 41.8 8.7 5.6e-08 32.3 0.1 3.3 3 0 0 3 3 3 2 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 EWM20868.1 - 0.00019 21.7 0.4 0.052 14.2 0.0 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat U3_assoc_6 PF08640.6 EWM20868.1 - 0.014 15.1 4.4 0.08 12.7 0.9 2.2 1 1 1 2 2 2 0 U3 small nucleolar RNA-associated protein 6 TPR_2 PF07719.12 EWM20868.1 - 0.016 15.1 0.0 2 8.5 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EWM20868.1 - 0.017 15.0 0.5 0.12 12.3 0.0 2.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EWM20868.1 - 0.099 12.4 0.1 1.1 9.2 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat GUN4 PF05419.7 EWM20868.1 - 0.42 10.4 2.7 13 5.5 0.2 2.3 1 1 1 2 2 2 0 GUN4-like MttA_Hcf106 PF02416.11 EWM20869.1 - 0.00065 18.7 0.0 0.0011 17.9 0.0 1.4 1 0 0 1 1 1 1 mttA/Hcf106 family zinc-ribbons_6 PF07191.7 EWM20870.1 - 0.035 13.9 1.5 0.85 9.4 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbons zf-dskA_traR PF01258.12 EWM20870.1 - 0.084 12.6 0.6 1.4 8.7 0.0 2.5 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger YdjO PF14169.1 EWM20870.1 - 4.6 6.7 6.3 5.4 6.5 0.2 2.6 3 0 0 3 3 3 0 Cold-inducible protein YdjO Lung_7-TM_R PF06814.8 EWM20871.1 - 5.5e-25 87.9 0.3 7.4e-25 87.5 0.2 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.4 EWM20871.1 - 0.00028 20.1 3.4 0.00044 19.5 2.3 1.3 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain PX PF00787.19 EWM20873.1 - 2e-07 30.7 0.2 4.4e-06 26.4 0.2 2.4 1 1 0 1 1 1 1 PX domain Adenylate_cycl PF01295.13 EWM20874.1 - 0.094 10.9 0.0 0.12 10.5 0.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase, class-I Pkinase PF00069.20 EWM20875.1 - 3.3e-08 33.0 0.0 4.2e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM20875.1 - 0.0042 16.1 0.0 0.0049 15.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Metallophos PF00149.23 EWM20876.1 - 9.5e-13 47.9 0.2 9.5e-13 47.9 0.1 2.3 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 EWM20876.1 - 5.6e-08 32.7 0.5 1.6e-07 31.2 0.3 1.9 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.2 EWM20876.1 - 1.1e-05 25.2 0.0 2.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain AMP-binding PF00501.23 EWM20877.1 - 3.1e-10 39.0 0.0 3.6e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Mito_fiss_reg PF05308.6 EWM20877.1 - 0.024 14.0 5.2 0.034 13.5 3.6 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator MOZ_SAS PF01853.13 EWM20878.1 - 5.3e-80 267.1 0.1 9.3e-80 266.3 0.1 1.3 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EWM20878.1 - 1.2e-14 53.7 0.4 2.7e-14 52.5 0.3 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.1 EWM20878.1 - 0.028 14.5 0.0 0.094 12.8 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain PBP1_TM PF14812.1 EWM20878.1 - 5.7 7.3 9.8 16 5.8 2.2 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Spore_coat_CotO PF14153.1 EWM20878.1 - 8.7 5.7 12.3 0.22 10.9 1.9 2.1 2 0 0 2 2 2 0 Spore coat protein CotO AMP-binding PF00501.23 EWM20879.1 - 1.3e-31 109.4 0.0 1.9e-15 56.2 0.0 2.3 2 1 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 EWM20879.1 - 9.1e-17 61.7 0.5 1.6e-16 61.0 0.3 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PQ-loop PF04193.9 EWM20880.1 - 7.9e-07 28.5 0.4 7.9e-07 28.5 0.2 1.8 2 0 0 2 2 2 1 PQ loop repeat DUF805 PF05656.9 EWM20880.1 - 0.077 12.8 1.2 0.13 12.0 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF805) DUF4149 PF13664.1 EWM20880.1 - 0.15 12.0 5.7 0.3 11.1 2.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) DUF3353 PF11833.3 EWM20880.1 - 0.34 10.3 3.1 0.53 9.6 2.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3353) ABC2_membrane_3 PF12698.2 EWM20880.1 - 0.66 8.9 7.0 0.79 8.6 4.9 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Brix PF04427.13 EWM20883.1 - 1.6e-38 132.3 0.1 2.3e-38 131.7 0.0 1.3 1 0 0 1 1 1 1 Brix domain NTR PF01759.16 EWM20883.1 - 0.1 12.1 0.2 0.37 10.3 0.1 1.9 2 0 0 2 2 2 0 UNC-6/NTR/C345C module Porin_OmpL1 PF11389.3 EWM20883.1 - 0.13 11.3 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Leptospira porin protein OmpL1 Ost4 PF10215.4 EWM20884.1 - 0.069 12.6 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Oligosaccaryltransferase 2-Hacid_dh_C PF02826.14 EWM20885.1 - 3.6e-60 202.1 0.0 5.3e-60 201.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EWM20885.1 - 0.0001 21.7 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.16 EWM20885.1 - 0.00029 20.7 0.2 0.00076 19.3 0.0 1.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.10 EWM20885.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EWM20885.1 - 0.03 13.6 0.0 0.051 12.9 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain AlaDh_PNT_C PF01262.16 EWM20885.1 - 0.033 13.7 0.4 0.3 10.6 0.0 2.5 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 EWM20886.1 - 5.1e-40 136.5 0.0 7.4e-40 135.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EWM20886.1 - 0.093 12.2 0.0 0.24 10.9 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain OTU PF02338.14 EWM20887.1 - 1.1e-07 32.4 0.0 1.9e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EWM20887.1 - 0.024 14.0 0.0 0.057 12.7 0.0 1.6 2 0 0 2 2 2 0 Peptidase C65 Otubain Pho88 PF10032.4 EWM20889.1 - 5.9e-27 94.1 0.7 9.9e-27 93.4 0.5 1.2 1 0 0 1 1 1 1 Phosphate transport (Pho88) eIF3_N PF09440.5 EWM20889.1 - 2e-05 24.7 1.8 0.00035 20.7 0.3 2.3 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain Ank_2 PF12796.2 EWM20889.1 - 0.00016 21.9 0.1 0.00041 20.6 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EWM20889.1 - 0.0015 18.2 0.1 0.006 16.3 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 EWM20889.1 - 0.0037 17.4 0.2 0.18 12.1 0.1 2.6 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EWM20889.1 - 0.031 14.7 0.0 0.1 13.1 0.0 2.0 1 1 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM20889.1 - 0.055 13.7 0.1 0.18 12.1 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeat Pro_isomerase PF00160.16 EWM20892.1 - 1.1e-42 145.8 0.0 1.3e-42 145.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EWM20893.1 - 4.5e-15 55.0 11.3 6.9e-05 22.4 0.0 3.3 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 EWM20893.1 - 3.3e-13 48.6 7.1 2.3e-06 26.9 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EWM20893.1 - 4.3e-13 48.0 7.5 2.6e-06 26.9 0.2 3.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EWM20893.1 - 0.00058 19.7 4.9 0.034 14.0 0.7 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 EWM20893.1 - 0.0012 18.0 0.1 0.0026 16.8 0.1 1.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EWM20893.1 - 0.0014 19.0 3.6 0.014 15.9 0.4 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat FAT PF02259.18 EWM20893.1 - 0.0029 16.6 2.5 0.041 12.8 0.5 2.1 1 1 0 2 2 2 1 FAT domain TPR_7 PF13176.1 EWM20893.1 - 0.004 16.8 2.5 2.7 8.0 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EWM20893.1 - 0.0048 16.5 1.6 0.08 12.7 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat OSCP PF00213.13 EWM20893.1 - 0.016 15.1 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit TPR_6 PF13174.1 EWM20893.1 - 0.15 12.6 1.0 1.8 9.1 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 EWM20893.1 - 0.3 10.9 6.8 7.7 6.4 0.6 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat PC-Esterase PF13839.1 EWM20895.1 - 1.7e-10 41.2 0.0 8.1e-10 38.9 0.0 1.9 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Inositol_P PF00459.20 EWM20896.1 - 9.3e-20 71.0 0.0 1.3e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family Herpes_BLLF1 PF05109.8 EWM20897.1 - 2.7 5.8 11.6 3.3 5.5 8.1 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) AAA PF00004.24 EWM20899.1 - 8.3e-13 48.6 0.0 1.5e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EWM20899.1 - 8.9e-06 25.8 0.1 0.00079 19.5 0.0 2.8 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EWM20899.1 - 1.4e-05 25.2 1.2 0.00046 20.2 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EWM20899.1 - 1.6e-05 24.5 0.0 5.3e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EWM20899.1 - 1.9e-05 23.8 0.0 4.4e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EWM20899.1 - 6.4e-05 22.7 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EWM20899.1 - 0.00011 22.9 0.0 0.00026 21.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EWM20899.1 - 0.00019 21.3 0.0 0.00034 20.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EWM20899.1 - 0.00056 18.7 0.0 0.69 8.5 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein Zeta_toxin PF06414.7 EWM20899.1 - 0.00097 18.2 0.0 0.0018 17.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 EWM20899.1 - 0.0012 19.1 0.0 0.0022 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EWM20899.1 - 0.0082 16.0 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 EWM20899.1 - 0.01 15.5 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 NTPase NACHT PF05729.7 EWM20899.1 - 0.02 14.5 0.0 0.051 13.2 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.1 EWM20899.1 - 0.028 14.3 0.0 0.082 12.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain TIP49 PF06068.8 EWM20899.1 - 0.029 13.0 0.0 0.048 12.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus IstB_IS21 PF01695.12 EWM20899.1 - 0.045 13.1 0.0 0.093 12.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.17 EWM20899.1 - 0.05 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 EWM20899.1 - 0.051 12.9 0.0 3 7.2 0.0 2.4 1 1 1 2 2 2 0 AAA-like domain DNA_pol3_delta PF06144.8 EWM20899.1 - 0.054 13.0 0.0 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_25 PF13481.1 EWM20899.1 - 0.067 12.5 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Polyoma_lg_T_C PF06431.6 EWM20899.1 - 0.16 10.6 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus Aminotran_4 PF01063.14 EWM20900.1 - 2.4e-30 105.7 0.0 3e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV TRIC PF05197.8 EWM20901.1 - 1e-07 31.5 0.5 1.6e-07 30.9 0.3 1.3 1 0 0 1 1 1 1 TRIC channel B_lectin PF01453.19 EWM20901.1 - 1.9e-06 27.7 0.0 8.2e-06 25.6 0.0 1.8 1 1 1 2 2 2 1 D-mannose binding lectin UPF0126 PF03458.8 EWM20901.1 - 0.00032 20.2 0.2 0.00032 20.2 0.2 2.0 2 0 0 2 2 2 1 UPF0126 domain YqjK PF13997.1 EWM20902.1 - 0.046 13.9 0.1 0.076 13.2 0.0 1.4 1 1 0 1 1 1 0 YqjK-like protein Antifungal_pept PF11410.3 EWM20902.1 - 0.064 13.3 0.1 0.064 13.3 0.1 2.1 2 0 0 2 2 2 0 Antifungal peptide ATP_bind_4 PF01902.12 EWM20903.1 - 5.6e-25 87.9 0.0 1.3e-24 86.8 0.0 1.5 1 1 0 1 1 1 1 ATP-binding region Arginosuc_synth PF00764.14 EWM20903.1 - 0.00079 18.5 0.0 0.0011 18.1 0.0 1.1 1 0 0 1 1 1 1 Arginosuccinate synthase tRNA_Me_trans PF03054.11 EWM20903.1 - 0.00081 18.0 0.1 0.001 17.6 0.0 1.1 1 0 0 1 1 1 1 tRNA methyl transferase HA2 PF04408.18 EWM20904.1 - 1.1e-17 63.9 0.2 4.9e-17 61.8 0.1 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EWM20904.1 - 1.3e-12 47.3 0.0 3.1e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain R3H PF01424.17 EWM20904.1 - 1.3e-10 40.8 0.0 3.5e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 R3H domain DEAD PF00270.24 EWM20904.1 - 1.3e-07 31.2 0.1 2.6e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 EWM20904.1 - 2.5e-06 27.2 0.0 6.1e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 EWM20904.1 - 0.00041 20.5 0.0 0.0022 18.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EWM20904.1 - 0.0085 15.0 0.2 0.035 13.0 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein ResIII PF04851.10 EWM20904.1 - 0.033 14.0 0.0 3.8 7.3 0.0 3.0 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_16 PF13191.1 EWM20904.1 - 0.43 10.5 7.8 9.4 6.1 0.9 4.4 4 1 0 4 4 4 0 AAA ATPase domain Peptidase_M20 PF01546.23 EWM20905.1 - 9.4e-35 119.8 0.0 1.3e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EWM20905.1 - 2.3e-07 30.5 0.0 5.1e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 Peptidase dimerisation domain Ribosomal_L7Ae PF01248.21 EWM20906.1 - 3.2e-20 71.4 0.7 7.3e-20 70.2 0.5 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Metal_resist PF13801.1 EWM20906.1 - 0.22 11.5 1.8 0.63 10.0 0.1 2.2 2 0 0 2 2 2 0 Heavy-metal resistance Gelsolin PF00626.17 EWM20907.1 - 0.00022 20.8 0.1 0.33 10.6 0.0 2.6 3 0 0 3 3 3 2 Gelsolin repeat UBN2 PF14223.1 EWM20907.1 - 0.053 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Patatin PF01734.17 EWM20908.1 - 1.6e-06 28.1 0.1 0.0022 17.9 0.0 2.3 2 0 0 2 2 2 2 Patatin-like phospholipase Abhydrolase_5 PF12695.2 EWM20908.1 - 0.014 15.1 0.1 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Rhomboid PF01694.17 EWM20909.1 - 5.7e-15 55.6 6.7 5.7e-15 55.6 4.7 1.8 2 1 0 2 2 2 1 Rhomboid family DER1 PF04511.10 EWM20909.1 - 0.0062 16.0 1.5 0.024 14.1 1.1 2.0 1 1 0 1 1 1 1 Der1-like family DUF4624 PF15417.1 EWM20909.1 - 0.16 11.5 0.2 0.25 10.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4624) Na_H_Exchanger PF00999.16 EWM20910.1 - 4e-30 104.6 20.2 3.3e-23 81.8 10.5 2.3 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family DUF1499 PF07386.6 EWM20913.1 - 4.8e-14 52.5 0.1 7.8e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1499) DUF4460 PF14687.1 EWM20913.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) DUF1150 PF06620.6 EWM20914.1 - 0.092 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1150) FA_desaturase PF00487.19 EWM20915.1 - 1.2e-41 142.8 16.1 1.2e-41 142.8 11.1 2.1 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 EWM20915.1 - 3.1e-19 68.5 0.1 8.8e-19 67.0 0.1 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain RNB PF00773.14 EWM20916.1 - 2.5e-31 109.1 0.0 4.4e-28 98.4 0.0 2.2 2 0 0 2 2 2 2 RNB domain AAA PF00004.24 EWM20917.1 - 3.1e-41 140.6 0.0 5.4e-41 139.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EWM20917.1 - 3e-07 30.6 0.3 1e-05 25.5 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EWM20917.1 - 9.1e-07 29.0 0.1 0.00046 20.3 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EWM20917.1 - 7.4e-06 25.7 0.1 5.4e-05 22.9 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EWM20917.1 - 2.5e-05 24.2 0.0 5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EWM20917.1 - 0.00011 21.2 0.0 0.0002 20.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EWM20917.1 - 0.00035 20.0 0.0 0.00066 19.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 EWM20917.1 - 0.00053 20.1 0.0 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_17 PF13207.1 EWM20917.1 - 0.0007 20.3 0.2 0.0024 18.6 0.1 2.1 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.1 EWM20917.1 - 0.001 19.3 0.0 0.003 17.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EWM20917.1 - 0.0017 18.0 0.1 0.0036 17.0 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 EWM20917.1 - 0.0023 17.3 0.2 0.028 13.8 0.1 2.3 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EWM20917.1 - 0.0026 16.9 0.0 0.0048 16.0 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EWM20917.1 - 0.0028 17.5 0.1 0.014 15.2 0.0 2.2 3 0 0 3 3 2 1 AAA domain DUF815 PF05673.8 EWM20917.1 - 0.0036 16.2 0.0 0.0061 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.8 EWM20917.1 - 0.0052 15.5 0.1 0.01 14.5 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus Sigma54_activat PF00158.21 EWM20917.1 - 0.0053 16.2 0.0 0.038 13.4 0.0 2.3 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.1 EWM20917.1 - 0.0062 16.5 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EWM20917.1 - 0.0073 16.2 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EWM20917.1 - 0.01 15.4 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 EWM20917.1 - 0.011 15.2 0.1 0.021 14.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EWM20917.1 - 0.018 14.6 0.0 0.058 13.0 0.0 1.9 1 1 1 2 2 2 0 NACHT domain Zeta_toxin PF06414.7 EWM20917.1 - 0.02 13.9 0.0 0.043 12.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin KaiC PF06745.8 EWM20917.1 - 0.022 13.8 0.2 0.068 12.2 0.0 1.9 3 0 0 3 3 3 0 KaiC DUF4200 PF13863.1 EWM20917.1 - 0.027 14.4 1.4 0.067 13.1 1.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) PhoH PF02562.11 EWM20917.1 - 0.028 13.6 0.1 0.052 12.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Arch_ATPase PF01637.13 EWM20917.1 - 0.032 13.9 0.1 0.37 10.4 0.0 2.6 2 1 0 2 2 2 0 Archaeal ATPase Sigma54_activ_2 PF14532.1 EWM20917.1 - 0.033 14.2 0.0 0.082 12.9 0.0 1.7 2 0 0 2 2 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EWM20917.1 - 0.034 13.0 0.0 0.059 12.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TBPIP PF07106.8 EWM20917.1 - 0.058 12.9 0.5 0.12 11.8 0.3 1.5 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) UPF0079 PF02367.12 EWM20917.1 - 0.06 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 PIF1 PF05970.9 EWM20917.1 - 0.06 12.2 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase ABC_tran PF00005.22 EWM20917.1 - 0.07 13.4 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter IFT57 PF10498.4 EWM20917.1 - 0.1 11.3 0.5 0.15 10.7 0.3 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 AAA_11 PF13086.1 EWM20917.1 - 0.1 12.1 0.1 0.29 10.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EWM20917.1 - 0.11 12.1 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 EWM20917.1 - 0.12 12.2 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Torsin DUF2075 PF09848.4 EWM20917.1 - 0.26 10.2 0.9 0.28 10.1 0.0 1.5 2 0 0 2 2 1 0 Uncharacterized conserved protein (DUF2075) IncA PF04156.9 EWM20917.1 - 0.93 9.0 3.6 1.9 8.0 2.5 1.4 1 0 0 1 1 1 0 IncA protein MFS_1 PF07690.11 EWM20918.1 - 2.9e-11 42.6 8.6 2.9e-11 42.6 6.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 EWM20918.1 - 0.00041 18.8 5.4 0.00059 18.3 3.7 1.3 1 1 0 1 1 1 1 MFS/sugar transport protein Sugar_tr PF00083.19 EWM20918.1 - 0.0014 17.2 8.1 0.0027 16.3 5.6 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter DUF4233 PF14017.1 EWM20918.1 - 1.5 8.8 8.6 0.3 11.0 3.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) GTP_EFTU PF00009.22 EWM20919.1 - 9.6e-52 175.1 0.0 1.4e-51 174.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 EWM20919.1 - 3.1e-45 152.5 0.9 3.1e-45 152.5 0.6 1.7 2 0 0 2 2 2 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 EWM20919.1 - 2.6e-19 68.8 0.0 6.2e-19 67.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EWM20919.1 - 1.5e-09 37.8 0.7 2.7e-09 37.0 0.5 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EWM20919.1 - 5.6e-07 29.5 0.0 2.2e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.17 EWM20919.1 - 0.0023 17.3 0.0 0.0058 16.0 0.0 1.6 1 0 0 1 1 1 1 Ras family EFG_II PF14492.1 EWM20919.1 - 0.0064 16.3 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.5 EWM20919.1 - 0.015 14.5 0.0 0.082 12.1 0.0 2.1 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Miro PF08477.8 EWM20919.1 - 0.044 14.2 0.0 0.16 12.4 0.0 2.0 1 1 1 2 2 2 0 Miro-like protein DUF1311 PF07007.7 EWM20920.1 - 2 8.5 6.7 12 6.0 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1311) Ribosom_S12_S23 PF00164.20 EWM20921.1 - 3.4e-40 136.2 0.5 4.1e-40 135.9 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Carboxyl_trans PF01039.17 EWM20922.1 - 2.2e-187 623.3 0.0 2.7e-187 623.0 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 EWM20922.1 - 0.0021 17.2 0.0 0.009 15.2 0.0 2.0 2 0 0 2 2 2 1 Malonate decarboxylase gamma subunit (MdcE) PH PF00169.24 EWM20923.1 - 3.5e-07 30.3 0.0 1.5e-06 28.3 0.0 2.0 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 EWM20923.1 - 8.1e-05 22.8 0.4 0.0005 20.2 0.3 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain R3H PF01424.17 EWM20924.1 - 3.1e-12 45.9 0.1 7.5e-12 44.7 0.1 1.6 1 0 0 1 1 1 1 R3H domain FAM222A PF15258.1 EWM20924.1 - 0.042 13.0 0.6 0.059 12.5 0.4 1.1 1 0 0 1 1 1 0 Protein family of FAM222A Daxx PF03344.10 EWM20924.1 - 1.1 7.6 20.2 2.1 6.7 14.0 1.5 1 0 0 1 1 1 0 Daxx Family Cellulase PF00150.13 EWM20925.1 - 5.2e-37 127.5 0.0 7.2e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TLC PF03219.9 EWM20928.1 - 3.2e-137 457.9 10.1 3.9e-137 457.7 7.0 1.0 1 0 0 1 1 1 1 TLC ATP/ADP transporter Cpn60_TCP1 PF00118.19 EWM20929.1 - 8.2e-149 496.3 0.0 9.8e-149 496.0 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF500 PF04366.7 EWM20929.1 - 0.0018 17.7 0.0 0.0041 16.5 0.0 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF500) MFS_1 PF07690.11 EWM20930.1 - 0.0051 15.5 0.7 0.0067 15.1 0.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EWM20930.1 - 0.0052 15.4 0.0 0.0061 15.1 0.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 EWM20930.1 - 0.013 15.2 0.0 0.028 14.1 0.0 1.5 1 1 0 1 1 1 0 MFS_1 like family SpoVAB PF13782.1 EWM20930.1 - 0.024 14.6 0.2 0.034 14.1 0.1 1.1 1 0 0 1 1 1 0 Stage V sporulation protein AB ADH_zinc_N PF00107.21 EWM20931.1 - 8.6e-10 38.2 0.0 4.3e-09 36.0 0.0 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EWM20931.1 - 2.1e-06 27.4 0.0 7.5e-06 25.6 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EWM20931.1 - 0.072 13.9 0.0 0.68 10.8 0.0 2.5 3 1 0 3 3 3 0 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EWM20932.1 - 7.1e-10 38.5 0.0 3.1e-09 36.4 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EWM20933.1 - 1.1e-10 42.5 0.0 3.7e-10 40.7 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EWM20933.1 - 9.5e-10 38.1 0.0 4e-09 36.1 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EWM20934.1 - 7.2e-10 38.5 0.0 3e-09 36.4 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EWM20934.1 - 0.086 13.7 0.0 0.52 11.2 0.0 2.3 3 1 0 3 3 3 0 Zinc-binding dehydrogenase CN_hydrolase PF00795.17 EWM20935.1 - 5.4e-22 78.0 0.0 1e-21 77.1 0.0 1.5 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 EWM20935.1 - 5.1e-18 64.8 0.0 1.4e-07 30.7 0.0 3.5 2 2 0 2 2 2 2 NAD synthase DnaJ PF00226.26 EWM20936.1 - 2.9e-26 90.9 0.0 4.3e-26 90.4 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Catalase PF00199.14 EWM20937.1 - 3.6e-186 618.4 0.1 4.3e-186 618.1 0.1 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EWM20937.1 - 1.7e-20 72.6 1.0 4.7e-20 71.2 0.3 2.0 2 0 0 2 2 2 1 Catalase-related immune-responsive Cytochrom_B561 PF03188.11 EWM20938.1 - 2.7e-18 66.1 9.2 2.7e-18 66.1 6.4 2.0 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 ATP1G1_PLM_MAT8 PF02038.11 EWM20938.1 - 0.038 12.9 0.2 0.11 11.5 0.1 1.7 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family DUF420 PF04238.7 EWM20938.1 - 0.63 9.9 13.4 0.045 13.7 4.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF420) Cytochrom_B561 PF03188.11 EWM20939.1 - 2.4e-18 66.2 9.2 2.4e-18 66.2 6.4 2.1 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 ATP1G1_PLM_MAT8 PF02038.11 EWM20939.1 - 0.036 13.0 0.2 0.1 11.6 0.1 1.7 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family DUF420 PF04238.7 EWM20939.1 - 0.33 10.9 12.8 0.043 13.7 4.8 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF420) Myb_DNA-binding PF00249.26 EWM20940.1 - 3.2e-13 49.5 0.2 5.2e-13 48.8 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EWM20940.1 - 2.7e-05 24.1 0.2 4.5e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF4096 PF13340.1 EWM20941.1 - 0.0027 17.5 0.5 0.0084 15.9 0.3 1.8 1 0 0 1 1 1 1 Putative transposase of IS4/5 family (DUF4096) IL11 PF07400.6 EWM20941.1 - 0.003 17.1 0.9 0.29 10.6 0.1 2.2 2 0 0 2 2 2 2 Interleukin 11 Neur_chan_memb PF02932.11 EWM20941.1 - 0.0043 16.9 0.4 0.024 14.5 0.0 1.9 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region DSPn PF14671.1 EWM20942.1 - 5.9e-51 172.1 0.2 1.3e-50 171.0 0.0 1.7 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 EWM20942.1 - 5.8e-14 51.8 0.0 1.8e-13 50.2 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EWM20942.1 - 2.6e-05 23.7 0.0 4.7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EWM20942.1 - 4.3e-05 23.5 0.1 9.2e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EWM20942.1 - 0.00078 19.7 0.4 0.0017 18.5 0.1 1.6 1 1 0 1 1 1 1 Tyrosine phosphatase family Mito_carr PF00153.22 EWM20943.1 - 8.7e-28 95.8 3.7 1.3e-15 56.8 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Nsp1_C PF05064.8 EWM20943.1 - 0.14 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Nsp1-like C-terminal region Mito_carr PF00153.22 EWM20944.1 - 8.7e-25 86.2 2.9 7.6e-16 57.5 0.0 2.9 3 0 0 3 3 3 2 Mitochondrial carrier protein Sigma70_r2 PF04542.9 EWM20947.1 - 8.1e-14 50.9 0.0 1.8e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r3 PF04539.11 EWM20947.1 - 0.004 17.0 1.8 0.014 15.2 0.2 2.3 2 0 0 2 2 2 1 Sigma-70 region 3 GCK PF07802.6 EWM20948.1 - 6.3e-07 29.4 0.1 8.7e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 GCK domain ATS3 PF06232.6 EWM20948.1 - 0.048 13.2 0.4 0.061 12.9 0.3 1.2 1 0 0 1 1 1 0 Embryo-specific protein 3, (ATS3) Myb_DNA-binding PF00249.26 EWM20949.1 - 3.7e-37 126.1 4.2 3.4e-13 49.4 0.1 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EWM20949.1 - 1.1e-34 118.2 2.6 3.5e-15 55.8 0.1 3.5 1 1 2 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.3 EWM20949.1 - 0.024 14.5 3.3 5.2 7.0 0.3 3.2 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.1 EWM20949.1 - 0.14 12.3 1.5 1.9 8.6 0.2 2.7 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Dimer_Tnp_hAT PF05699.9 EWM20950.1 - 2.3e-09 36.7 0.1 3.5e-08 32.9 0.1 2.4 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF2390 PF09523.5 EWM20950.1 - 0.53 10.4 5.9 4.3 7.5 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2390) CIAPIN1 PF05093.8 EWM20951.1 - 5.2e-19 68.1 17.2 5.1e-18 65.0 11.9 2.2 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis TPR_14 PF13428.1 EWM20952.1 - 0.00018 21.8 0.0 0.00061 20.1 0.0 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EWM20952.1 - 0.00022 20.6 0.0 0.0082 15.7 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EWM20952.1 - 0.00054 19.6 0.2 0.01 15.6 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EWM20952.1 - 0.006 17.2 0.0 0.021 15.4 0.0 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EWM20952.1 - 0.011 15.5 0.1 0.45 10.4 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EWM20952.1 - 0.012 15.7 0.1 0.015 15.4 0.1 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EWM20952.1 - 0.017 15.0 0.2 0.03 14.2 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 EWM20952.1 - 0.087 12.7 0.0 0.18 11.7 0.0 1.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EWM20952.1 - 0.12 12.0 0.2 0.51 10.0 0.1 1.9 1 1 0 1 1 1 0 TPR repeat PPR PF01535.15 EWM20952.1 - 0.12 12.4 0.4 0.54 10.3 0.0 2.2 2 1 0 2 2 2 0 PPR repeat ketoacyl-synt PF00109.21 EWM20954.1 - 2.3e-05 24.0 0.1 3.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KH_1 PF00013.24 EWM20955.1 - 1.8e-12 46.7 0.5 1.2e-05 24.9 0.1 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 EWM20955.1 - 2.2e-07 30.3 6.6 0.0017 17.9 0.3 2.8 2 1 0 2 2 2 2 KH domain KH_2 PF07650.12 EWM20955.1 - 0.00012 21.5 2.3 0.38 10.3 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_4 PF13083.1 EWM20955.1 - 0.00033 20.2 0.2 0.28 10.8 0.0 2.4 2 0 0 2 2 2 2 KH domain DUF1180 PF06679.7 EWM20957.1 - 0.013 15.3 0.7 0.023 14.6 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Chorion_2 PF03964.10 EWM20957.1 - 0.25 11.9 3.2 0.53 10.8 2.3 1.5 1 0 0 1 1 1 0 Chorion family 2 OCD_Mu_crystall PF02423.10 EWM20961.1 - 0.00099 17.9 0.0 0.0012 17.6 0.0 1.1 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family dCMP_cyt_deam_1 PF00383.17 EWM20962.1 - 2.3e-06 27.1 0.1 4e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EWM20962.1 - 0.018 14.8 0.3 0.06 13.1 0.0 1.9 2 0 0 2 2 2 0 Bd3614-like deaminase ATG_C PF09333.6 EWM20963.1 - 0.047 13.8 0.0 0.058 13.5 0.0 1.2 1 0 0 1 1 1 0 ATG C terminal domain DUF3613 PF12266.3 EWM20966.1 - 0.085 12.3 0.2 0.18 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3613) Glyco_transf_17 PF04724.8 EWM20967.1 - 7.5e-31 107.4 0.0 8.7e-31 107.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 17 TMEM61 PF15105.1 EWM20967.1 - 0.012 15.1 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 TMEM61 protein family ADH_N_assoc PF13823.1 EWM20967.1 - 0.46 10.1 1.9 1.3 8.7 1.3 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated CD36 PF01130.16 EWM20969.1 - 0.11 10.7 0.0 0.13 10.5 0.0 1.0 1 0 0 1 1 1 0 CD36 family CD36 PF01130.16 EWM20970.1 - 4.1e-05 22.0 0.0 0.0027 16.0 0.0 2.5 2 1 0 2 2 2 2 CD36 family RICTOR_phospho PF14665.1 EWM20972.1 - 0.3 11.1 1.5 16 5.6 0.1 2.0 1 1 1 2 2 2 0 Rapamycin-insensitive companion of mTOR, phosphorylation-site Fasciclin PF02469.17 EWM20973.1 - 9.4e-19 67.6 0.0 1.3e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain DUF2064 PF09837.4 EWM20974.1 - 1.7e-28 98.6 0.3 3.1e-28 97.8 0.2 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2064) NTP_transf_3 PF12804.2 EWM20974.1 - 0.017 15.2 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 MobA-like NTP transferase domain RRM_1 PF00076.17 EWM20975.1 - 2.8e-07 30.0 0.0 4.7e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) F-box-like PF12937.2 EWM20975.1 - 1.1e-06 28.2 0.1 1.1e-06 28.2 0.1 3.8 4 0 0 4 4 4 1 F-box-like LRR_6 PF13516.1 EWM20975.1 - 9.5e-05 22.0 18.8 0.62 10.2 0.1 7.7 8 0 0 8 8 8 2 Leucine Rich repeat LRR_1 PF00560.28 EWM20975.1 - 0.00016 21.2 15.0 0.51 10.5 0.1 7.2 6 2 0 6 6 6 2 Leucine Rich Repeat RRM_5 PF13893.1 EWM20975.1 - 0.00066 19.4 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM20975.1 - 0.0012 18.7 0.0 0.0029 17.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) LRR_4 PF12799.2 EWM20975.1 - 0.021 14.4 14.5 0.8 9.4 0.1 4.9 3 2 1 5 5 5 0 Leucine Rich repeats (2 copies) F-box PF00646.28 EWM20975.1 - 0.09 12.4 0.0 0.09 12.4 0.0 3.8 4 1 0 4 4 4 0 F-box domain LRR_7 PF13504.1 EWM20975.1 - 0.41 11.0 21.8 0.88 10.0 0.1 6.7 8 0 0 8 8 8 0 Leucine rich repeat LRR_8 PF13855.1 EWM20975.1 - 2 8.2 19.2 3.5 7.4 1.4 4.8 5 2 1 6 6 6 0 Leucine rich repeat RPAP2_Rtr1 PF04181.8 EWM20977.1 - 6.2e-10 39.0 0.0 1.3e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Rtr1/RPAP2 family Radical_SAM PF04055.16 EWM20978.1 - 0.029 14.5 0.1 0.035 14.2 0.0 1.1 1 0 0 1 1 1 0 Radical SAM superfamily TPR_1 PF00515.23 EWM20982.1 - 1.6e-24 84.4 6.5 8.1e-10 37.8 0.2 5.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 EWM20982.1 - 2.9e-24 84.5 11.4 4.2e-13 48.7 1.6 3.2 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.12 EWM20982.1 - 7.4e-22 75.4 11.0 4.6e-10 38.6 0.6 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EWM20982.1 - 5.6e-19 68.3 26.6 1.3e-08 35.2 3.1 3.6 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.1 EWM20982.1 - 2e-16 59.6 9.1 2.6e-10 40.0 1.0 3.4 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EWM20982.1 - 2.5e-16 58.6 13.8 0.0001 22.6 0.3 5.6 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 EWM20982.1 - 2.3e-15 55.4 3.3 0.00097 19.1 0.1 5.4 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 EWM20982.1 - 2.6e-13 48.6 2.3 7.5e-05 22.2 0.0 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 EWM20982.1 - 2.5e-12 45.5 9.3 3.1e-05 23.4 0.1 5.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 EWM20982.1 - 3.5e-11 43.2 9.2 6e-06 26.5 0.2 3.6 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_9 PF13371.1 EWM20982.1 - 5.8e-09 35.6 10.9 3.5e-06 26.7 1.0 3.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 EWM20982.1 - 1.6e-07 31.3 3.5 0.11 12.9 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.1 EWM20982.1 - 1.2e-05 25.0 6.6 0.045 13.6 0.4 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.1 EWM20982.1 - 5e-05 23.3 2.7 0.087 12.9 0.1 3.2 2 1 2 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EWM20982.1 - 9.8e-05 22.4 0.7 0.031 14.4 0.3 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 XPC-binding PF09280.6 EWM20982.1 - 0.0059 16.0 0.0 0.84 9.1 0.0 3.1 3 0 0 3 3 3 1 XPC-binding domain TPR_4 PF07721.9 EWM20982.1 - 0.038 14.4 0.4 0.038 14.4 0.2 4.0 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_15 PF13429.1 EWM20982.1 - 0.054 12.5 5.2 3.4 6.6 0.5 2.9 1 1 1 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.12 EWM20982.1 - 0.055 13.7 2.4 0.61 10.3 0.1 2.8 3 1 0 3 3 3 0 Bacterial transcriptional activator domain ChAPs PF09295.5 EWM20982.1 - 0.075 11.7 0.1 11 4.6 0.0 2.8 2 1 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) Fis1_TPR_C PF14853.1 EWM20982.1 - 0.086 12.7 0.4 0.37 10.7 0.1 2.1 2 0 0 2 2 1 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.13 EWM20982.1 - 0.086 12.7 0.6 5.1 7.0 0.0 3.3 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain NYD-SP12_N PF15015.1 EWM20982.1 - 0.099 10.8 0.2 0.13 10.4 0.1 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal DnaJ_CXXCXGXG PF00684.14 EWM20983.1 - 0.018 15.0 0.7 0.037 14.0 0.5 1.5 1 0 0 1 1 1 0 DnaJ central domain Retinal PF15449.1 EWM20983.1 - 1.4 6.4 11.8 1.7 6.1 8.1 1.0 1 0 0 1 1 1 0 Retinal protein G_glu_transpept PF01019.16 EWM20984.1 - 3.8e-146 487.5 0.0 4.3e-146 487.3 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF2378 PF09536.5 EWM20984.1 - 0.057 12.9 0.6 0.96 8.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2378) TPR_16 PF13432.1 EWM20985.1 - 0.057 14.1 3.4 0.72 10.6 0.4 3.1 1 1 1 2 2 2 0 Tetratricopeptide repeat PPR_2 PF13041.1 EWM20985.1 - 0.1 12.5 0.0 78 3.3 0.0 4.0 4 0 0 4 4 4 0 PPR repeat family RRM_1 PF00076.17 EWM20986.1 - 1.3e-21 75.9 0.1 1.8e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM20986.1 - 3e-15 55.9 0.0 4.1e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM20986.1 - 8.4e-11 41.5 0.0 1.3e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EWM20986.1 - 1.6e-05 24.6 0.0 2.3e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.1 EWM20986.1 - 1.8e-05 24.3 0.0 2.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EWM20986.1 - 0.007 16.0 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Limkain b1 SNARE_assoc PF09335.6 EWM20987.1 - 1.8e-12 47.5 6.2 1.8e-12 47.5 4.3 2.4 2 1 0 2 2 2 1 SNARE associated Golgi protein DUF2930 PF11152.3 EWM20989.1 - 0.011 14.9 0.2 0.042 12.9 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2930) FrhB_FdhB_N PF04422.8 EWM20989.1 - 0.46 10.3 3.2 8.8 6.2 0.1 2.5 2 1 0 2 2 2 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term Thioesterase PF00975.15 EWM20990.1 - 1.1e-21 78.1 0.0 1.8e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EWM20990.1 - 3.6e-08 33.5 0.0 7.3e-07 29.2 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM20990.1 - 2.4e-06 27.3 0.0 3.3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EWM20990.1 - 0.065 12.7 0.1 0.75 9.3 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold XRCC4 PF06632.7 EWM20991.1 - 2.4e-07 29.9 0.1 3.2e-07 29.5 0.1 1.1 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 Myb_DNA-bind_6 PF13921.1 EWM20993.1 - 1.8e-30 104.8 3.4 3.2e-13 49.5 0.4 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EWM20993.1 - 2.1e-30 104.5 7.1 1.5e-12 47.3 0.0 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.3 EWM20993.1 - 0.0081 16.0 3.5 7.1 6.5 0.1 3.9 3 1 1 4 4 4 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.1 EWM20993.1 - 1.3 9.1 3.6 12 6.1 0.2 3.1 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain V-SNARE_C PF12352.3 EWM20996.1 - 6.3e-07 29.3 0.8 7.4e-07 29.1 0.5 1.1 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Gp_dh_C PF02800.15 EWM20997.1 - 4.8e-68 227.5 0.0 6.8e-68 227.0 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EWM20997.1 - 6.1e-60 201.5 1.0 1.1e-59 200.7 0.1 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EWM20997.1 - 0.029 14.2 0.1 0.19 11.6 0.0 2.3 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Sec15 PF04091.7 EWM20998.1 - 4.2e-33 114.9 0.0 7.2e-33 114.2 0.0 1.3 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like DUF1214 PF06742.6 EWM20999.1 - 6.2e-06 26.6 0.0 4.7e-05 23.8 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1214) UPF0104 PF03706.8 EWM20999.1 - 0.014 14.7 0.6 0.067 12.4 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0104) APH PF01636.18 EWM21001.1 - 3.7e-38 131.6 0.1 2.6e-37 128.8 0.1 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family HAD_2 PF13419.1 EWM21001.1 - 3.1e-13 50.3 0.1 8.1e-12 45.7 0.0 2.8 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase EcKinase PF02958.15 EWM21001.1 - 4.6e-06 25.9 0.0 8.7e-06 25.0 0.0 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase Hydrolase PF00702.21 EWM21001.1 - 5.5e-06 26.9 0.0 7e-05 23.3 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase RIO1 PF01163.17 EWM21001.1 - 8.3e-05 22.0 0.0 0.002 17.4 0.0 2.3 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.15 EWM21001.1 - 0.039 13.5 0.0 0.077 12.5 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase HAD PF12710.2 EWM21001.1 - 0.047 13.8 0.0 0.12 12.5 0.0 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF1679 PF07914.6 EWM21001.1 - 0.2 10.2 0.0 0.46 9.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) SNARE PF05739.14 EWM21002.1 - 2.7e-06 26.9 1.4 2.9e-05 23.6 0.2 2.3 2 0 0 2 2 2 1 SNARE domain V-SNARE_C PF12352.3 EWM21002.1 - 0.014 15.4 0.3 0.21 11.7 0.0 2.3 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus 2OG-FeII_Oxy_3 PF13640.1 EWM21003.1 - 0.00024 21.5 0.5 0.0023 18.4 0.1 2.5 3 0 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily CDP-OH_P_transf PF01066.16 EWM21004.1 - 4.1e-16 59.1 9.9 1e-15 57.8 6.9 1.8 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Complex1_LYR PF05347.10 EWM21005.1 - 8.2e-08 31.9 1.6 1.6e-07 30.9 0.1 1.9 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EWM21005.1 - 2e-07 31.0 0.1 2e-07 31.0 0.1 1.6 2 0 0 2 2 2 1 Complex1_LYR-like GldM_N PF12081.3 EWM21005.1 - 0.021 14.3 1.2 0.023 14.1 0.8 1.1 1 0 0 1 1 1 0 GldM N-terminal domain DUF1997 PF09366.5 EWM21006.1 - 1.1e-10 41.4 0.2 1.5e-09 37.7 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1997) Gp_dh_C PF02800.15 EWM21007.1 - 1.1e-70 236.1 0.1 1.6e-70 235.6 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EWM21007.1 - 3.3e-53 179.7 0.1 6.7e-53 178.7 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EWM21007.1 - 0.0085 15.2 0.0 0.017 14.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.15 EWM21007.1 - 0.018 14.9 0.2 0.09 12.7 0.0 2.3 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Gp_dh_C PF02800.15 EWM21008.1 - 1.2e-70 235.9 0.1 1.9e-70 235.3 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EWM21008.1 - 3.8e-53 179.4 0.1 7.8e-53 178.4 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EWM21008.1 - 0.0095 15.1 0.0 0.019 14.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.15 EWM21008.1 - 0.022 14.6 0.2 0.099 12.5 0.0 2.2 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus C2 PF00168.25 EWM21009.1 - 4.4e-05 23.2 0.0 9.7e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 C2 domain ABC1 PF03109.11 EWM21010.1 - 3.3e-23 81.8 0.0 5.3e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 EWM21010.1 - 0.0055 16.4 1.4 0.74 9.5 1.0 3.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family GCK PF07802.6 EWM21011.1 - 1.8e-10 40.7 0.1 3.7e-10 39.7 0.1 1.6 1 0 0 1 1 1 1 GCK domain RunxI PF08504.6 EWM21011.1 - 7.2 7.1 11.0 12 6.3 0.3 3.0 2 1 1 3 3 3 0 Runx inhibition domain AAA PF00004.24 EWM21012.1 - 5.1e-36 123.7 0.0 6.7e-29 100.7 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EWM21012.1 - 1.3e-11 44.8 2.3 0.0017 18.3 0.1 4.0 2 2 1 4 4 3 3 AAA ATPase domain AAA_22 PF13401.1 EWM21012.1 - 1.2e-08 35.1 1.0 0.11 12.6 0.1 4.1 2 2 1 3 3 3 2 AAA domain AAA_19 PF13245.1 EWM21012.1 - 1.2e-07 31.3 9.5 0.0016 18.1 1.2 3.3 3 0 0 3 3 2 2 Part of AAA domain AAA_17 PF13207.1 EWM21012.1 - 4.1e-07 30.8 1.7 0.0091 16.8 0.0 2.8 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EWM21012.1 - 2.1e-06 27.3 0.1 0.0014 18.0 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_5 PF07728.9 EWM21012.1 - 1.3e-05 24.9 0.6 0.12 12.1 0.1 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EWM21012.1 - 2.3e-05 24.3 0.1 0.059 13.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 EWM21012.1 - 6.8e-05 21.7 0.2 0.03 13.0 0.0 2.1 2 0 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 EWM21012.1 - 9.1e-05 21.9 8.9 0.11 11.9 0.3 4.3 2 2 2 4 4 4 1 AAA domain PhoH PF02562.11 EWM21012.1 - 0.00015 21.0 0.1 0.11 11.7 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein Zeta_toxin PF06414.7 EWM21012.1 - 0.00016 20.8 0.7 0.065 12.3 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin RuvB_N PF05496.7 EWM21012.1 - 0.00017 20.6 0.2 0.12 11.4 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EWM21012.1 - 0.00018 20.5 0.0 0.054 12.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_23 PF13476.1 EWM21012.1 - 0.00098 19.5 0.0 0.075 13.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EWM21012.1 - 0.0013 18.5 0.0 2.2 7.9 0.0 3.1 3 0 0 3 3 3 1 Archaeal ATPase Mg_chelatase PF01078.16 EWM21012.1 - 0.0019 17.4 1.4 0.074 12.2 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EWM21012.1 - 0.0025 18.0 0.2 1.4 9.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EWM21012.1 - 0.0026 17.3 0.9 0.046 13.3 0.1 2.2 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 EWM21012.1 - 0.0033 16.9 0.1 0.17 11.4 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_10 PF12846.2 EWM21012.1 - 0.0042 16.5 0.3 7.9 5.8 0.0 3.1 2 1 1 3 3 3 0 AAA-like domain AAA_14 PF13173.1 EWM21012.1 - 0.013 15.4 0.0 0.97 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EWM21012.1 - 0.019 14.4 0.0 4.3 6.7 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain NACHT PF05729.7 EWM21012.1 - 0.019 14.6 2.9 0.44 10.1 0.1 3.2 3 0 0 3 3 3 0 NACHT domain AAA_28 PF13521.1 EWM21012.1 - 0.022 14.7 0.0 3.9 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EWM21012.1 - 0.024 14.7 0.0 2.7 8.1 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.1 EWM21012.1 - 0.027 14.0 1.2 0.39 10.2 0.1 2.1 2 0 0 2 2 2 0 AAA domain DUF927 PF06048.6 EWM21012.1 - 0.033 13.4 0.0 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF927) AAA_30 PF13604.1 EWM21012.1 - 0.054 13.0 3.7 2.7 7.5 0.1 2.9 3 0 0 3 3 2 0 AAA domain AAA_3 PF07726.6 EWM21012.1 - 0.072 12.6 0.0 1.8 8.1 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EWM21012.1 - 0.076 11.8 0.2 1.3 7.8 0.0 2.3 2 1 0 2 2 2 0 Type II/IV secretion system protein AAA_21 PF13304.1 EWM21012.1 - 0.082 12.8 0.0 9.2 6.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EWM21012.1 - 0.14 12.4 0.2 17 5.6 0.0 3.0 3 0 0 3 3 2 0 ABC transporter NB-ARC PF00931.17 EWM21012.1 - 0.2 10.4 0.0 14 4.4 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain KaiC PF06745.8 EWM21012.1 - 0.35 9.9 0.4 4.4 6.3 0.0 2.6 2 1 1 3 3 3 0 KaiC DAP3 PF10236.4 EWM21012.1 - 0.42 9.4 0.1 21 3.9 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 DUF2075 PF09848.4 EWM21012.1 - 0.98 8.3 1.3 5.8 5.7 0.1 2.4 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2075) DUF3605 PF12239.3 EWM21014.1 - 5.8e-05 22.9 1.5 0.00075 19.3 1.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) DUF3605 PF12239.3 EWM21015.1 - 3.2e-05 23.8 1.3 0.00046 20.0 0.9 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) Brix PF04427.13 EWM21016.1 - 8.5e-32 110.3 0.0 1.2e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 Brix domain Glyco_transf_20 PF00982.16 EWM21018.1 - 6.6e-179 595.3 0.0 8.3e-179 595.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EWM21018.1 - 2.7e-67 226.1 0.0 4.2e-67 225.4 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase NUP50 PF08911.6 EWM21018.1 - 0.019 15.3 0.1 0.05 13.9 0.1 1.6 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) Glycos_transf_1 PF00534.15 EWM21018.1 - 0.065 12.6 0.1 1 8.7 0.0 2.7 2 1 0 2 2 2 0 Glycosyl transferases group 1 Hydrolase_3 PF08282.7 EWM21018.1 - 0.065 12.7 0.0 3.5 7.1 0.0 2.3 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase FlxA PF14282.1 EWM21018.1 - 0.21 11.5 3.0 0.47 10.4 2.1 1.5 1 0 0 1 1 1 0 FlxA-like protein WD40 PF00400.27 EWM21019.1 - 1.5e-13 49.9 1.1 1.1e-05 25.1 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat Gpi1 PF05024.10 EWM21020.1 - 3.3e-22 79.0 5.9 3.5e-20 72.4 0.1 2.5 2 1 0 2 2 2 2 N-acetylglucosaminyl transferase component (Gpi1) Flavi_NS4A PF01350.12 EWM21020.1 - 0.11 12.0 0.4 0.19 11.3 0.3 1.3 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A Bap31 PF05529.7 EWM21023.1 - 2.2e-11 43.5 0.1 3.4e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like Conotoxin PF02950.12 EWM21023.1 - 0.048 14.4 0.0 7 7.5 0.0 2.4 2 0 0 2 2 2 0 Conotoxin DUF1772 PF08592.6 EWM21023.1 - 0.087 12.5 0.1 0.52 10.0 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Baculo_11_kDa PF06143.6 EWM21023.1 - 0.25 10.7 1.0 5.6 6.4 0.0 2.5 3 0 0 3 3 3 0 Baculovirus 11 kDa family WD40_alt PF14077.1 EWM21023.1 - 0.33 10.6 2.7 0.72 9.5 1.9 1.5 1 0 0 1 1 1 0 Alternative WD40 repeat motif IncA PF04156.9 EWM21023.1 - 0.38 10.3 9.0 0.82 9.2 6.2 1.6 1 1 0 1 1 1 0 IncA protein Oxidored_q3 PF00499.15 EWM21023.1 - 0.46 10.2 7.4 0.2 11.4 2.0 2.0 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Phlebovirus_NSM PF07246.6 EWM21023.1 - 2.7 7.0 5.5 4.2 6.4 3.8 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M AAA_11 PF13086.1 EWM21024.1 - 4.4e-27 95.1 1.3 6.4e-26 91.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EWM21024.1 - 2.1e-25 89.3 0.0 3.7e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EWM21024.1 - 4.4e-10 39.1 0.1 2.5e-09 36.7 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EWM21024.1 - 1.3e-05 24.8 0.0 0.16 11.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain DEAD PF00270.24 EWM21024.1 - 0.00054 19.5 0.0 0.0015 18.0 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EWM21024.1 - 0.00054 19.8 1.3 0.00076 19.3 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 EWM21024.1 - 0.00068 19.0 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.16 EWM21024.1 - 0.003 16.8 0.2 0.0078 15.5 0.0 1.7 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 EWM21024.1 - 0.013 15.6 0.0 0.034 14.2 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain PhoH PF02562.11 EWM21024.1 - 0.033 13.4 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.1 EWM21024.1 - 0.041 14.0 0.0 0.15 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EWM21024.1 - 0.042 14.0 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 EWM21024.1 - 0.14 11.0 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Lipase_3 PF01764.20 EWM21025.1 - 1.7e-14 53.6 0.0 2.6e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.15 EWM21025.1 - 0.092 12.2 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Pkinase PF00069.20 EWM21026.1 - 9.6e-41 139.6 0.0 1.2e-40 139.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM21026.1 - 2.7e-17 62.7 0.0 3.7e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EWM21026.1 - 2.3e-05 24.2 0.4 7.1e-05 22.6 0.3 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EWM21026.1 - 0.0015 17.6 0.0 0.0024 16.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EWM21026.1 - 0.0088 15.4 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 RIO1 family DUF4242 PF14026.1 EWM21026.1 - 0.04 13.9 0.0 0.08 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4242) Ion_trans PF00520.26 EWM21027.1 - 1e-25 90.1 5.0 1.3e-25 89.8 3.4 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans PF00520.26 EWM21028.1 - 1.3e-46 158.3 5.6 1.7e-46 158.0 3.9 1.1 1 0 0 1 1 1 1 Ion transport protein APH PF01636.18 EWM21029.1 - 0.0011 18.7 0.9 0.0058 16.3 0.6 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Ribosomal_S16 PF00886.14 EWM21030.1 - 4.6e-28 96.7 0.1 7.5e-28 96.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 Ank_2 PF12796.2 EWM21034.1 - 2e-24 85.7 0.0 3.8e-10 39.9 0.0 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EWM21034.1 - 7.2e-21 72.9 1.1 7.5e-08 31.8 0.1 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 EWM21034.1 - 1.6e-16 59.8 0.2 1.6e-05 24.9 0.0 4.3 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EWM21034.1 - 6.2e-14 52.0 0.0 5.7e-06 26.6 0.1 3.9 3 2 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM21034.1 - 1.6e-12 46.3 0.0 0.00066 19.6 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat GTP_EFTU PF00009.22 EWM21037.1 - 6.3e-37 126.8 3.6 1e-36 126.1 0.8 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EWM21037.1 - 1.1e-27 95.9 5.3 3.5e-27 94.4 3.7 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EWM21037.1 - 1.4e-12 47.5 9.1 1.7e-06 28.0 0.2 3.5 3 0 0 3 3 3 2 Elongation factor Tu domain 2 IF2_N PF04760.10 EWM21037.1 - 3.5e-09 36.1 0.0 7.4e-09 35.1 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.18 EWM21037.1 - 9.6e-09 35.2 0.0 2.2e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EWM21037.1 - 1.3e-05 25.6 0.1 2.4e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 EWM21037.1 - 5.4e-05 22.5 0.6 0.0005 19.3 0.1 2.5 2 1 0 2 2 2 1 Ferrous iron transport protein B SRPRB PF09439.5 EWM21037.1 - 0.00012 21.3 0.0 0.0005 19.3 0.0 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EWM21037.1 - 0.00091 18.6 0.0 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 Ras family PduV-EutP PF10662.4 EWM21037.1 - 0.0085 15.5 0.5 0.019 14.4 0.0 1.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 EWM21037.1 - 0.058 13.2 0.1 6.2 6.6 0.0 2.6 1 1 1 2 2 2 0 Dynamin family Pkinase PF00069.20 EWM21038.1 - 1.3e-09 37.5 0.0 2e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM21038.1 - 0.01 14.8 0.0 0.024 13.6 0.0 1.5 2 0 0 2 2 2 0 Protein tyrosine kinase DUF4431 PF14485.1 EWM21039.1 - 0.068 12.8 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) SET PF00856.23 EWM21040.1 - 9.1e-19 68.3 0.0 7.2e-18 65.4 0.0 2.1 1 1 0 1 1 1 1 SET domain zf-RING_4 PF14570.1 EWM21040.1 - 0.03 13.9 1.9 0.51 9.9 0.1 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Epimerase PF01370.16 EWM21041.1 - 1e-11 44.7 0.0 1.5e-10 40.9 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EWM21041.1 - 4.2e-08 33.4 0.0 0.00018 21.6 0.0 2.5 3 0 0 3 3 3 2 NADH(P)-binding 3Beta_HSD PF01073.14 EWM21041.1 - 5e-06 25.4 0.0 0.011 14.4 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EWM21041.1 - 0.021 13.7 0.0 0.03 13.1 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.8 EWM21041.1 - 0.022 14.0 0.0 0.17 11.0 0.0 2.0 2 0 0 2 2 2 0 NmrA-like family adh_short PF00106.20 EWM21041.1 - 0.022 14.6 0.1 1.2 8.9 0.0 2.4 2 1 0 2 2 2 0 short chain dehydrogenase NAD_binding_4 PF07993.7 EWM21041.1 - 0.022 13.6 0.0 1.1 8.1 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein DUF4588 PF15251.1 EWM21041.1 - 0.092 12.7 0.9 0.14 12.1 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) ABC2_membrane PF01061.19 EWM21043.1 - 2.5e-12 46.4 12.1 2.6e-12 46.3 8.4 1.0 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 EWM21043.1 - 0.11 11.5 14.7 0.13 11.2 10.2 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein ABC_tran PF00005.22 EWM21044.1 - 7.7e-17 61.8 0.0 1.1e-16 61.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 EWM21044.1 - 3.2e-11 42.7 20.9 4.3e-11 42.3 14.5 1.2 1 0 0 1 1 1 1 ABC-2 type transporter AAA_29 PF13555.1 EWM21044.1 - 0.00013 21.3 0.3 0.00027 20.4 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EWM21044.1 - 0.0004 19.8 0.2 0.00075 18.9 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 EWM21044.1 - 0.0059 16.5 0.0 0.024 14.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EWM21044.1 - 0.0062 15.7 0.1 0.011 14.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EWM21044.1 - 0.008 16.1 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EWM21044.1 - 0.011 15.8 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EWM21044.1 - 0.013 16.2 0.0 0.035 14.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EWM21044.1 - 0.021 14.6 0.1 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EWM21044.1 - 0.039 13.9 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EWM21044.1 - 0.043 13.3 0.0 0.063 12.7 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC2_membrane_3 PF12698.2 EWM21044.1 - 0.044 12.8 11.3 0.057 12.4 7.9 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_10 PF12846.2 EWM21044.1 - 0.076 12.4 0.3 0.1 11.9 0.2 1.1 1 0 0 1 1 1 0 AAA-like domain NACHT PF05729.7 EWM21044.1 - 0.14 11.8 0.2 0.3 10.7 0.1 1.6 1 0 0 1 1 1 0 NACHT domain Dynamin_N PF00350.18 EWM21044.1 - 0.16 11.7 0.3 0.31 10.8 0.1 1.5 2 0 0 2 2 2 0 Dynamin family EB PF01683.13 EWM21045.1 - 4 7.5 18.1 1 9.4 6.7 2.6 2 0 0 2 2 2 0 EB module Paf1 PF03985.8 EWM21045.1 - 9.4 4.8 8.1 14 4.2 5.6 1.1 1 0 0 1 1 1 0 Paf1 Pkinase PF00069.20 EWM21046.1 - 2.3e-31 108.9 0.0 3.2e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM21046.1 - 5.4e-16 58.4 0.0 8.9e-16 57.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EWM21048.1 - 1.7e-26 92.9 0.0 3.7e-26 91.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM21048.1 - 1e-09 37.8 0.0 2e-07 30.3 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase E_Pc_C PF06752.7 EWM21048.1 - 0.93 8.9 13.3 0.45 9.9 0.9 2.2 2 0 0 2 2 2 0 Enhancer of Polycomb C-terminus DUF3721 PF12518.3 EWM21049.1 - 0.12 12.0 0.4 0.19 11.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function TAF1D PF15333.1 EWM21050.1 - 0.11 12.2 1.2 0.12 12.1 0.9 1.1 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D TT_ORF1 PF02956.9 EWM21050.1 - 9.8 4.5 12.4 11 4.3 8.6 1.0 1 0 0 1 1 1 0 TT viral orf 1 NIF PF03031.13 EWM21051.1 - 2.1e-40 137.9 0.0 5.5e-40 136.6 0.0 1.6 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 EWM21051.1 - 3.2e-06 27.4 0.6 8.6e-06 26.0 0.2 1.8 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase Pkinase PF00069.20 EWM21052.1 - 8.1e-28 97.2 0.0 3e-14 52.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EWM21052.1 - 1e-09 37.8 0.0 2.5e-06 26.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 EWM21052.1 - 1.6e-06 27.3 0.0 2.7e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.15 EWM21052.1 - 0.028 13.5 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase SET PF00856.23 EWM21053.1 - 1.6e-19 70.7 0.2 3.2e-18 66.5 0.0 2.5 2 1 0 2 2 2 1 SET domain PY_rept_46 PF09689.5 EWM21054.1 - 0.012 15.9 1.4 0.02 15.1 1.0 1.3 1 0 0 1 1 1 0 Plasmodium yoelii repeat (PY_rept_46) DUF390 PF04094.9 EWM21056.1 - 0.15 10.0 0.1 0.19 9.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) GATase PF00117.23 EWM21057.1 - 6.3e-05 22.5 0.0 7.6e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I DUF4031 PF13223.1 EWM21057.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4031) Pentapeptide PF00805.17 EWM21058.1 - 3.3e-17 61.3 2.4 1.5e-09 36.8 0.3 2.4 1 1 1 2 2 2 2 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 EWM21058.1 - 4.3e-13 48.8 2.3 5.9e-13 48.4 1.6 1.2 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 EWM21058.1 - 5.4e-12 45.3 7.0 1.8e-06 27.7 2.0 2.2 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) DUF737 PF05300.6 EWM21062.1 - 0.061 13.2 9.4 0.1 12.5 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Peptidase_S49_N PF08496.5 EWM21062.1 - 0.072 12.8 2.9 0.14 11.9 2.0 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Endonuc_Holl PF10107.4 EWM21062.1 - 0.52 9.9 4.1 0.91 9.2 2.8 1.4 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Phlebovirus_NSM PF07246.6 EWM21062.1 - 0.83 8.7 4.9 1.3 8.1 3.4 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF1990 PF09348.5 EWM21063.1 - 1.2e-16 60.7 2.3 2.9e-16 59.4 1.6 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1990) FAD_binding_4 PF01565.18 EWM21066.1 - 7.3e-11 41.7 0.0 9.2e-11 41.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SCAN PF02023.12 EWM21066.1 - 0.05 13.0 0.0 0.24 10.8 0.0 1.9 2 0 0 2 2 2 0 SCAN domain Rgp1 PF08737.5 EWM21068.1 - 3.6e-08 32.9 0.2 4.8e-08 32.5 0.2 1.2 1 0 0 1 1 1 1 Rgp1 Abhydrolase_6 PF12697.2 EWM21069.1 - 3.6e-28 99.0 0.2 3.6e-28 99.0 0.2 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM21069.1 - 2.7e-12 46.6 0.0 3.8e-11 42.9 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EWM21069.1 - 4.6e-07 29.5 0.0 8.7e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EWM21069.1 - 0.0017 17.9 0.1 0.067 12.7 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 EWM21069.1 - 0.0025 17.1 0.0 1 8.5 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family BSP_II PF05432.6 EWM21070.1 - 0.047 12.9 10.3 0.059 12.6 7.1 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) FAM176 PF14851.1 EWM21070.1 - 0.98 9.0 5.5 1.5 8.5 3.8 1.3 1 0 0 1 1 1 0 FAM176 family Pox_RNA_Pol_19 PF05320.7 EWM21070.1 - 2.4 7.9 5.3 3.3 7.4 3.6 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Myc_N PF01056.13 EWM21070.1 - 2.5 7.1 8.4 3.1 6.8 5.8 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Daxx PF03344.10 EWM21070.1 - 3.2 6.1 7.6 3.4 6.0 5.3 1.1 1 0 0 1 1 1 0 Daxx Family CENP-B_dimeris PF09026.5 EWM21070.1 - 3.4 7.9 8.9 5.8 7.2 6.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Spore_coat_CotO PF14153.1 EWM21070.1 - 5 6.5 8.3 6.5 6.1 5.8 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF2890 PF11081.3 EWM21070.1 - 5.7 6.9 8.9 7.7 6.5 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) UPF0079 PF02367.12 EWM21072.1 - 4.8e-20 71.4 0.0 9.9e-20 70.3 0.0 1.5 1 1 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 EWM21072.1 - 0.0032 17.1 0.1 0.0067 16.0 0.1 1.5 1 0 0 1 1 1 1 NACHT domain AAA_24 PF13479.1 EWM21072.1 - 0.0049 16.4 0.0 0.007 15.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EWM21072.1 - 0.0069 15.5 0.1 0.0098 15.0 0.1 1.2 1 0 0 1 1 1 1 KaiC AAA_19 PF13245.1 EWM21072.1 - 0.0085 15.8 0.3 0.016 14.9 0.2 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 EWM21072.1 - 0.023 14.9 0.0 0.036 14.2 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EWM21072.1 - 0.052 13.6 0.0 0.091 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EWM21072.1 - 0.064 12.6 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EWM21072.1 - 0.14 12.0 0.1 0.23 11.4 0.1 1.3 1 0 0 1 1 1 0 AAA ATPase domain MSA-2c PF12238.3 EWM21072.1 - 0.21 11.2 1.7 0.29 10.7 1.2 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c Baculo_11_kDa PF06143.6 EWM21074.1 - 0.17 11.2 0.7 0.22 10.8 0.5 1.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family Alg6_Alg8 PF03155.10 EWM21075.1 - 1.6e-15 56.9 0.1 2.3e-15 56.4 0.1 1.2 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family NAD_binding_11 PF14833.1 EWM21078.1 - 4.2e-05 23.6 0.0 5.8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Transcrip_reg PF01709.15 EWM21079.1 - 2.3e-18 66.2 3.6 2.9e-18 65.8 2.5 1.1 1 0 0 1 1 1 1 Transcriptional regulator TH1 PF04858.8 EWM21079.1 - 0.14 10.3 0.3 0.15 10.2 0.2 1.1 1 0 0 1 1 1 0 TH1 protein SIP1 PF04938.7 EWM21081.1 - 9.1e-08 31.7 0.8 8.6e-07 28.5 0.5 2.0 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) SIP1 PF04938.7 EWM21082.1 - 2.3e-16 59.8 0.0 3e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) FTHFS PF01268.14 EWM21084.1 - 9.1e-39 132.8 0.0 9.9e-39 132.7 0.0 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase Thioesterase PF00975.15 EWM21085.1 - 5.3e-24 85.7 0.0 3.3e-17 63.5 0.0 2.1 2 0 0 2 2 2 2 Thioesterase domain Abhydrolase_6 PF12697.2 EWM21085.1 - 8.9e-09 35.5 0.1 1.5e-08 34.8 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM21085.1 - 8.6e-06 25.5 0.0 1.9e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EWM21085.1 - 0.0032 16.9 0.0 0.0062 16.0 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 EWM21085.1 - 0.074 12.6 0.0 0.093 12.2 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold AMP-binding PF00501.23 EWM21089.1 - 0.0015 17.0 0.0 0.0054 15.1 0.0 1.7 1 1 1 2 2 2 2 AMP-binding enzyme DUF2177 PF09945.4 EWM21091.1 - 9.3e-13 48.2 11.1 4.4e-12 46.0 7.7 1.8 1 1 0 1 1 1 1 Predicted membrane protein (DUF2177) DUF2324 PF10086.4 EWM21091.1 - 0.00064 18.9 2.0 0.026 13.7 1.0 2.2 2 0 0 2 2 2 2 Putative membrane peptidase family (DUF2324) UQ_con PF00179.21 EWM21093.1 - 4e-42 142.9 0.0 4.9e-42 142.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EWM21093.1 - 0.0007 19.3 0.0 0.00075 19.2 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EWM21093.1 - 0.029 14.2 0.2 0.042 13.7 0.1 1.3 1 1 0 1 1 1 0 RWD domain UEV PF05743.8 EWM21093.1 - 0.043 13.4 0.3 0.065 12.9 0.2 1.3 1 1 0 1 1 1 0 UEV domain HIT PF01230.18 EWM21094.1 - 0.013 16.0 0.1 0.025 15.1 0.1 1.4 1 0 0 1 1 1 0 HIT domain Asp_protease PF09668.5 EWM21095.1 - 1.2e-60 202.5 0.2 1.9e-60 201.8 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EWM21095.1 - 1.6e-10 41.3 0.1 6.1e-10 39.4 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease UBA PF00627.26 EWM21095.1 - 4.2e-08 32.7 1.5 2.1e-05 24.1 0.0 3.0 3 0 0 3 3 3 2 UBA/TS-N domain gag-asp_proteas PF13975.1 EWM21095.1 - 1.2e-06 28.1 0.1 3.5e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 EWM21095.1 - 1.4e-06 28.1 0.0 3.3e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 EWM21095.1 - 6.1e-06 26.2 0.0 9.9e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease ubiquitin PF00240.18 EWM21095.1 - 6.2e-05 22.3 0.0 0.00012 21.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EWM21095.1 - 0.00011 21.7 0.0 0.00026 20.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Matrilin_ccoil PF10393.4 EWM21095.1 - 0.78 9.1 4.9 0.33 10.3 0.2 2.4 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin CDP-OH_P_transf PF01066.16 EWM21096.1 - 2.7e-15 56.5 0.6 4.9e-14 52.4 0.4 2.1 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase DUF4140 PF13600.1 EWM21097.1 - 0.37 11.2 3.6 0.82 10.1 2.5 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF4407 PF14362.1 EWM21097.1 - 0.81 8.5 3.9 1.1 8.1 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Vps5 PF09325.5 EWM21097.1 - 0.91 8.7 5.8 1.3 8.2 4.0 1.1 1 0 0 1 1 1 0 Vps5 C terminal like GAS PF13851.1 EWM21097.1 - 1 8.5 4.7 1.3 8.2 3.2 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Methyltransf_11 PF08241.7 EWM21098.1 - 2.4e-05 24.7 0.0 5.7e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM21098.1 - 3e-05 24.5 0.0 6.2e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM21098.1 - 9.6e-05 22.1 0.0 0.00024 20.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM21098.1 - 0.00044 20.2 0.3 0.0014 18.6 0.1 1.9 2 1 0 2 2 2 1 Methyltransferase domain Rhodanese PF00581.15 EWM21098.1 - 0.00048 20.4 0.0 0.00086 19.6 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain MTS PF05175.9 EWM21098.1 - 0.00085 18.7 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EWM21098.1 - 0.00092 19.5 0.0 0.015 15.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM21098.1 - 0.00092 18.8 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EWM21098.1 - 0.0024 17.0 0.0 0.0036 16.5 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_12 PF08242.7 EWM21098.1 - 0.0036 17.7 0.0 0.0079 16.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.10 EWM21098.1 - 0.18 10.9 0.0 0.36 9.9 0.0 1.5 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_4 PF02390.12 EWM21098.1 - 0.19 10.7 0.0 0.38 9.7 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase SWIM PF04434.12 EWM21099.1 - 4.6e-05 22.7 1.1 4.6e-05 22.7 0.7 2.1 2 1 1 3 3 3 1 SWIM zinc finger AdoHcyase PF05221.12 EWM21100.1 - 3e-122 406.7 0.1 3.8e-122 406.3 0.0 1.1 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EWM21100.1 - 2.5e-78 261.5 4.5 3.8e-78 260.9 3.1 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EWM21100.1 - 3.6e-10 39.2 0.5 6.5e-10 38.4 0.3 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 EWM21100.1 - 0.00014 21.8 0.6 0.0038 17.2 0.3 2.8 2 1 0 2 2 2 1 TrkA-N domain IlvN PF07991.7 EWM21100.1 - 0.00016 21.1 0.5 0.0003 20.1 0.4 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_7 PF13241.1 EWM21100.1 - 0.0046 17.1 0.4 0.011 15.9 0.2 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding ELFV_dehydrog PF00208.16 EWM21100.1 - 0.0083 15.7 0.7 0.02 14.4 0.5 1.7 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase THF_DHG_CYH_C PF02882.14 EWM21100.1 - 0.05 12.6 3.9 0.2 10.7 2.7 1.8 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 EWM21100.1 - 0.079 13.0 1.0 0.21 11.7 0.7 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Aminotran_1_2 PF00155.16 EWM21101.1 - 1.8e-39 135.7 0.0 2.5e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EWM21101.1 - 0.00023 20.0 0.0 0.00078 18.2 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V OKR_DC_1 PF01276.15 EWM21101.1 - 0.0068 14.9 0.0 0.027 13.0 0.0 1.8 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain DegT_DnrJ_EryC1 PF01041.12 EWM21101.1 - 0.012 14.6 0.2 0.36 9.8 0.1 2.2 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family AP_endonuc_2 PF01261.19 EWM21104.1 - 4.3e-24 84.9 0.0 2e-20 73.0 0.0 2.3 1 1 1 2 2 2 2 Xylose isomerase-like TIM barrel CAF1 PF04857.15 EWM21105.1 - 2.3e-42 145.1 0.0 1.1e-41 142.8 0.0 1.8 1 1 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.15 EWM21105.1 - 9.1e-05 22.0 0.0 0.0042 16.5 0.0 2.5 2 0 0 2 2 2 1 3'-5' exonuclease Inositol_P PF00459.20 EWM21106.1 - 1.1e-38 133.0 0.7 1.5e-38 132.6 0.5 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family Fcf1 PF04900.7 EWM21107.1 - 3.3e-14 52.8 0.0 9.9e-14 51.2 0.0 1.8 1 0 0 1 1 1 1 Fcf1 GFO_IDH_MocA PF01408.17 EWM21108.1 - 8.3e-23 81.1 0.0 1.4e-22 80.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EWM21108.1 - 1.4e-07 31.3 0.0 2.6e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Mito_carr PF00153.22 EWM21109.1 - 3.5e-65 215.7 1.1 1e-23 82.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Sel1 PF08238.7 EWM21110.1 - 0.00013 22.4 0.6 1.6 9.5 0.0 3.8 3 0 0 3 3 3 2 Sel1 repeat Imm37 PF15598.1 EWM21110.1 - 0.0046 16.8 0.4 0.015 15.2 0.1 1.9 2 0 0 2 2 2 1 Immunity protein 37 TPR_16 PF13432.1 EWM21110.1 - 8 7.2 15.0 6.9 7.4 1.1 4.1 3 1 2 5 5 5 0 Tetratricopeptide repeat adh_short PF00106.20 EWM21111.1 - 1.1e-16 61.2 0.6 1.5e-16 60.7 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EWM21111.1 - 1.5e-09 37.7 0.6 2.2e-09 37.2 0.4 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EWM21111.1 - 2.3e-09 37.3 0.0 3.2e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EWM21111.1 - 0.00085 18.8 0.1 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EWM21111.1 - 0.012 15.6 0.4 0.017 15.1 0.3 1.6 1 1 0 1 1 1 0 NADH(P)-binding AlaDh_PNT_C PF01262.16 EWM21111.1 - 0.065 12.7 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Kelch_4 PF13418.1 EWM21112.1 - 1.2e-22 79.3 16.5 2.4e-07 30.4 0.1 6.5 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.1 EWM21112.1 - 2.9e-19 68.6 17.8 0.0004 20.4 0.0 7.9 7 1 0 7 7 7 4 Galactose oxidase, central domain zf-RING_2 PF13639.1 EWM21112.1 - 1.4e-14 53.5 4.3 2.4e-14 52.8 3.0 1.4 1 0 0 1 1 1 1 Ring finger domain Kelch_6 PF13964.1 EWM21112.1 - 3.2e-12 46.0 6.7 0.02 15.0 0.0 6.5 6 0 0 6 6 6 2 Kelch motif zf-C3HC4 PF00097.20 EWM21112.1 - 9.3e-09 34.8 1.7 1.5e-08 34.1 1.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EWM21112.1 - 9.3e-08 32.0 0.9 2e-07 30.9 0.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger Kelch_1 PF01344.20 EWM21112.1 - 6.8e-07 28.7 1.7 0.055 13.0 0.0 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 EWM21112.1 - 7.4e-07 28.6 7.5 0.46 10.3 0.0 5.8 6 0 0 6 6 6 1 Kelch motif Kelch_5 PF13854.1 EWM21112.1 - 1.1e-06 28.4 10.8 0.031 14.2 0.0 5.5 6 0 0 6 6 5 2 Kelch motif zf-C3HC4_2 PF13923.1 EWM21112.1 - 1.5e-06 28.0 3.8 2.5e-06 27.3 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EWM21112.1 - 1.1e-05 24.9 1.8 1.8e-05 24.3 1.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EWM21112.1 - 3e-05 23.5 2.8 5.7e-05 22.6 2.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EWM21112.1 - 0.0021 17.8 3.7 0.0037 17.1 2.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EWM21112.1 - 0.0024 17.6 3.0 0.011 15.5 2.1 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.6 EWM21112.1 - 0.04 13.9 0.7 0.076 13.0 0.5 1.4 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.3 EWM21112.1 - 0.086 12.8 3.6 0.41 10.6 2.5 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 EWM21112.1 - 0.13 12.3 6.4 0.023 14.7 1.9 1.7 2 0 0 2 2 1 0 RING-variant domain PHD PF00628.24 EWM21112.1 - 0.21 11.3 2.8 0.34 10.6 1.9 1.4 1 0 0 1 1 1 0 PHD-finger COPIIcoated_ERV PF07970.7 EWM21113.1 - 3.9e-28 98.6 0.1 7.9e-28 97.5 0.1 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EWM21113.1 - 2.4e-26 91.5 1.3 5.3e-26 90.4 0.4 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Thioredoxin PF00085.15 EWM21113.1 - 9.1e-22 76.7 0.0 2.1e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EWM21113.1 - 0.00011 22.3 0.6 0.00036 20.7 0.1 2.1 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EWM21113.1 - 0.00014 21.8 0.0 0.0004 20.4 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.1 EWM21113.1 - 0.042 13.8 0.1 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 Thioredoxin-like Inhibitor_I78 PF11720.3 EWM21113.1 - 0.083 12.6 0.0 0.76 9.5 0.0 2.3 2 0 0 2 2 2 0 Peptidase inhibitor I78 family TFIIS_C PF01096.13 EWM21114.1 - 1.2e-18 66.4 3.4 1.2e-18 66.4 2.4 2.3 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EWM21114.1 - 1.1e-06 28.1 5.8 1.6e-06 27.7 2.0 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 EWM21114.1 - 0.01 15.5 7.2 0.042 13.6 0.2 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Lar_restr_allev PF14354.1 EWM21114.1 - 0.038 14.2 6.2 0.13 12.6 0.2 2.3 2 1 0 2 2 2 0 Restriction alleviation protein Lar Nudix_N_2 PF14803.1 EWM21114.1 - 0.045 13.4 2.4 0.045 13.4 1.7 2.5 3 1 0 3 3 3 0 Nudix N-terminal CCG PF02754.11 EWM21114.1 - 0.082 12.9 0.6 0.15 12.0 0.4 1.4 1 0 0 1 1 1 0 Cysteine-rich domain Elf1 PF05129.8 EWM21114.1 - 0.28 10.9 0.1 0.28 10.9 0.1 2.7 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like Fer4_8 PF13183.1 EWM21114.1 - 0.46 10.5 7.8 27 4.8 5.4 2.6 1 1 0 1 1 1 0 4Fe-4S dicluster domain zf-piccolo PF05715.8 EWM21114.1 - 0.76 9.8 8.5 3.1 7.8 0.8 2.5 2 1 0 2 2 2 0 Piccolo Zn-finger DUF329 PF03884.9 EWM21114.1 - 0.92 9.1 8.2 0.36 10.4 1.4 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF329) DUF2387 PF09526.5 EWM21114.1 - 1.1 9.1 4.0 7.7 6.5 0.3 2.2 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) Zn-ribbon_8 PF09723.5 EWM21114.1 - 1.6 8.7 8.4 2 8.4 0.0 3.7 4 0 0 4 4 4 0 Zinc ribbon domain zf-ribbon_3 PF13248.1 EWM21114.1 - 2.6 7.3 9.5 0.51 9.6 1.0 2.8 2 1 0 2 2 2 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 EWM21114.1 - 4.6 6.6 13.1 0.11 11.8 1.5 2.6 2 2 0 2 2 2 0 TFIIB zinc-binding PHD PF00628.24 EWM21114.1 - 7.8 6.2 9.6 5.2 6.8 1.4 2.8 2 1 1 3 3 3 0 PHD-finger ThuA PF06283.6 EWM21116.1 - 0.004 16.8 0.2 0.017 14.8 0.0 2.1 2 0 0 2 2 2 1 Trehalose utilisation Bot1p PF12298.3 EWM21116.1 - 0.058 13.3 0.1 0.058 13.3 0.1 2.8 3 0 0 3 3 3 0 Eukaryotic mitochondrial regulator protein HEAT PF02985.17 EWM21118.1 - 8.1e-08 31.7 10.0 3.1 8.1 0.0 7.0 7 0 0 7 7 7 4 HEAT repeat UAA PF08449.6 EWM21119.1 - 7.9e-67 225.3 21.1 9.8e-67 225.0 14.6 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EWM21119.1 - 0.0091 16.0 15.4 0.0091 16.0 10.7 3.0 2 2 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 EWM21119.1 - 0.0095 15.5 21.7 0.024 14.2 10.9 3.0 2 1 0 2 2 2 1 Triose-phosphate Transporter family NAD_binding_10 PF13460.1 EWM21120.1 - 9.8e-27 94.1 0.0 1.5e-26 93.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EWM21120.1 - 5.1e-09 35.7 0.1 9e-09 34.9 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EWM21120.1 - 3.5e-07 29.9 0.0 5.6e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EWM21120.1 - 8.4e-07 27.9 0.0 1.4e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RRM_1 PF00076.17 EWM21121.1 - 7.7e-20 70.3 0.0 1.3e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM21121.1 - 1.1e-15 57.3 0.0 1.9e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.1 EWM21121.1 - 8.8e-11 41.7 0.0 8.8e-10 38.5 0.0 2.3 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_5 PF13893.1 EWM21121.1 - 3.2e-10 39.6 0.0 5.3e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 EWM21121.1 - 0.013 14.7 1.2 0.031 13.5 0.8 1.7 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal Clat_adaptor_s PF01217.15 EWM21122.1 - 2.5e-44 150.4 1.4 2.9e-44 150.2 1.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain BCDHK_Adom3 PF10436.4 EWM21123.1 - 4.5e-44 149.8 0.0 6.3e-44 149.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EWM21123.1 - 1.7e-17 63.1 0.0 2.8e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EWM21123.1 - 0.00027 20.5 0.0 0.00043 19.9 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cellulase PF00150.13 EWM21124.1 - 3.3e-30 105.2 0.9 4.5e-30 104.8 0.6 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF2372 PF10178.4 EWM21125.1 - 1.5e-16 60.3 0.0 2.3e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2372) chaperone_DMP PF10448.4 EWM21125.1 - 0.075 12.9 0.0 0.17 11.7 0.0 1.6 1 1 0 1 1 1 0 20S proteasome chaperone EF1G PF00647.14 EWM21126.1 - 2.2e-36 123.8 0.2 4e-36 122.9 0.2 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 EWM21126.1 - 1.2e-15 57.2 2.2 2e-15 56.5 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EWM21126.1 - 7.9e-15 54.7 0.0 2.1e-14 53.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EWM21126.1 - 2.9e-12 46.6 0.1 8.1e-12 45.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EWM21126.1 - 1.3e-10 41.6 3.5 5.6e-09 36.3 0.0 2.6 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EWM21126.1 - 3.7e-09 36.3 0.3 1e-08 34.9 0.2 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EWM21126.1 - 8.3e-07 28.9 0.0 2.7e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain DUF3692 PF12469.3 EWM21126.1 - 0.061 13.5 1.0 0.22 11.7 0.7 2.1 1 1 0 1 1 1 0 CRISPR-associated protein Atrophin-1 PF03154.10 EWM21126.1 - 9.3 4.2 7.7 12 3.8 5.3 1.1 1 0 0 1 1 1 0 Atrophin-1 family Noc2 PF03715.8 EWM21127.1 - 1.7e-72 243.8 0.0 3e-72 243.0 0.0 1.3 1 0 0 1 1 1 1 Noc2p family RRM_1 PF00076.17 EWM21128.1 - 5.1e-40 134.9 0.0 1.1e-18 66.5 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM21128.1 - 4.9e-34 116.1 0.0 5e-14 52.0 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM21128.1 - 2.6e-19 68.7 0.0 1.6e-05 24.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CbiG_mid PF11761.3 EWM21128.1 - 0.00069 19.8 0.1 1.9 8.8 0.0 2.8 3 0 0 3 3 3 2 Cobalamin biosynthesis central region Limkain-b1 PF11608.3 EWM21128.1 - 0.0059 16.3 0.1 0.34 10.6 0.0 3.0 2 1 1 3 3 3 1 Limkain b1 tRNA-synt_1b PF00579.20 EWM21129.1 - 4.2e-08 32.6 0.0 1.1e-07 31.2 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF2059 PF09832.4 EWM21131.1 - 6.6e-08 32.4 0.7 1.8e-07 31.0 0.5 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2059) Ycf1 PF05758.7 EWM21131.1 - 0.0028 15.4 2.9 0.0037 15.0 2.0 1.1 1 0 0 1 1 1 1 Ycf1 B12-binding_2 PF02607.12 EWM21131.1 - 0.048 13.6 0.7 0.73 9.9 0.1 2.3 2 0 0 2 2 2 0 B12 binding domain Neur_chan_memb PF02932.11 EWM21131.1 - 0.44 10.3 2.8 0.73 9.6 1.9 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF106 PF01956.11 EWM21131.1 - 9.7 5.6 6.1 3.3 7.2 2.4 1.7 1 1 0 1 1 1 0 Integral membrane protein DUF106 Phage_GP20 PF06810.6 EWM21132.1 - 0.00019 20.8 6.8 0.00019 20.8 4.7 3.5 3 1 0 3 3 3 1 Phage minor structural protein GP20 Reo_sigmaC PF04582.7 EWM21132.1 - 1.1 8.3 7.4 18 4.4 0.0 3.1 3 0 0 3 3 3 0 Reovirus sigma C capsid protein VDE PF07137.6 EWM21133.1 - 1.5e-73 246.9 1.9 2.2e-73 246.3 1.3 1.2 1 0 0 1 1 1 1 Violaxanthin de-epoxidase (VDE) INCENP_ARK-bind PF03941.10 EWM21134.1 - 2e-06 27.5 0.0 4.7e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region ADH_zinc_N PF00107.21 EWM21135.1 - 1.3e-20 73.2 0.1 2.4e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EWM21135.1 - 1.5e-19 69.7 1.6 3e-19 68.7 1.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EWM21135.1 - 0.044 13.3 1.0 1.3 8.5 0.2 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Met_10 PF02475.11 EWM21135.1 - 0.081 12.5 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 Met-10+ like-protein TrkA_N PF02254.13 EWM21135.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.14 EWM21135.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SET PF00856.23 EWM21136.1 - 0.00023 21.5 0.0 0.0017 18.6 0.0 2.3 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.6 EWM21136.1 - 0.0026 17.6 0.1 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding SET PF00856.23 EWM21137.1 - 0.00024 21.4 0.0 0.0018 18.5 0.0 2.3 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.6 EWM21137.1 - 0.0028 17.5 0.1 0.012 15.4 0.0 2.1 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding Aminotran_1_2 PF00155.16 EWM21138.1 - 6e-73 245.8 0.0 6.9e-73 245.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF1688 PF07958.6 EWM21139.1 - 7.4e-154 512.2 0.0 8.6e-154 512.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) IF4E PF01652.13 EWM21140.1 - 2.6e-38 131.1 0.0 3.2e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E IF4E PF01652.13 EWM21141.1 - 2.1e-38 131.4 0.0 2.5e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Myb_DNA-binding PF00249.26 EWM21142.1 - 7.4e-30 102.7 6.1 3e-16 59.1 0.7 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EWM21142.1 - 9.4e-21 73.6 8.9 1.4e-14 53.9 1.0 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EWM21142.1 - 0.058 13.5 4.9 0.19 11.8 0.2 2.6 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EWM21142.1 - 0.36 10.7 3.5 1.9 8.4 0.0 2.7 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain Ecm29 PF13001.2 EWM21143.1 - 7.1e-21 74.2 0.0 8.2e-21 74.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome stabiliser Sdh_cyt PF01127.17 EWM21144.1 - 1.5e-17 63.5 0.6 2e-17 63.1 0.4 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2269 PF10027.4 EWM21144.1 - 0.073 12.8 0.2 0.85 9.3 0.1 2.2 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) Sdh_cyt PF01127.17 EWM21145.1 - 1.9e-13 50.2 1.3 2.6e-13 49.8 0.9 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Pkinase PF00069.20 EWM21146.1 - 1.9e-55 187.8 0.0 2.3e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM21146.1 - 1.8e-30 105.8 0.0 2.2e-30 105.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EWM21146.1 - 6.6e-07 28.5 0.1 0.0001 21.3 0.1 2.6 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.9 EWM21146.1 - 1e-05 24.7 0.1 1.7e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EWM21146.1 - 0.022 14.4 3.2 0.81 9.3 2.1 2.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family F-box-like PF12937.2 EWM21147.1 - 0.0076 15.9 0.1 0.016 14.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EWM21147.1 - 0.0081 15.8 0.8 0.029 14.0 0.5 2.0 1 1 0 1 1 1 1 F-box domain PCI PF01399.22 EWM21148.1 - 5.1e-15 55.6 0.5 1.8e-14 53.9 0.0 2.2 2 0 0 2 2 2 1 PCI domain Gp-FAR-1 PF05823.7 EWM21148.1 - 0.0083 16.0 0.6 0.022 14.7 0.4 1.7 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) TPR_21 PF09976.4 EWM21148.1 - 0.011 15.7 6.3 0.014 15.3 2.5 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 EWM21148.1 - 0.45 11.0 2.9 8.2 7.1 0.6 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat KH_3 PF13014.1 EWM21149.1 - 0.11 12.2 0.0 0.51 10.0 0.0 2.1 2 0 0 2 2 2 0 KH domain Ribosomal_S21 PF01165.15 EWM21150.1 - 0.003 16.9 1.2 0.003 16.9 0.8 1.8 2 0 0 2 2 2 1 Ribosomal protein S21 TIM21 PF08294.6 EWM21150.1 - 0.2 11.3 0.1 0.2 11.3 0.1 1.6 1 1 1 2 2 2 0 TIM21 Erythro-docking PF09277.6 EWM21150.1 - 1.4 8.6 0.0 1.4 8.6 0.0 2.7 3 0 0 3 3 3 0 Erythronolide synthase, docking OmpH PF03938.9 EWM21151.1 - 0.014 15.2 6.7 0.017 15.0 4.6 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Cas6 PF09559.5 EWM21151.1 - 0.099 12.3 0.6 0.12 12.0 0.4 1.2 1 0 0 1 1 1 0 Cas6 Crispr V_ATPase_I PF01496.14 EWM21151.1 - 0.14 9.9 1.5 0.17 9.7 1.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CALCOCO1 PF07888.6 EWM21151.1 - 0.21 9.8 8.4 0.25 9.5 5.8 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like TMEM247 PF15444.1 EWM21151.1 - 1.2 8.8 4.7 1.5 8.5 3.1 1.3 1 1 0 1 1 1 0 Transmembrane protein 247 DUF3135 PF11333.3 EWM21151.1 - 2.5 8.2 6.9 6.7 6.9 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) Mito_fiss_reg PF05308.6 EWM21152.1 - 1.9 7.7 14.2 1.9 7.8 9.8 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Ribosomal_L7Ae PF01248.21 EWM21153.1 - 2.5e-23 81.3 0.4 3.4e-23 80.9 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family X8 PF07983.8 EWM21153.1 - 0.069 13.6 0.0 0.1 13.1 0.0 1.3 1 0 0 1 1 1 0 X8 domain Ribonuc_red_lgC PF02867.10 EWM21155.1 - 1.4e-213 710.3 0.0 3.5e-213 709.0 0.0 1.7 2 0 0 2 2 2 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EWM21155.1 - 8.7e-21 73.5 0.0 2.2e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EWM21155.1 - 4.2e-17 62.3 0.0 9.2e-17 61.2 0.0 1.6 1 0 0 1 1 1 1 ATP cone domain SKI PF01202.17 EWM21156.1 - 2.2e-35 121.8 0.0 3.2e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_17 PF13207.1 EWM21156.1 - 9.9e-08 32.8 0.0 3e-07 31.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EWM21156.1 - 4.5e-06 26.9 0.1 1.9e-05 25.0 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EWM21156.1 - 9.2e-06 25.5 0.0 3e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EWM21156.1 - 0.0022 18.2 0.0 0.0041 17.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EWM21156.1 - 0.0045 16.9 0.0 0.014 15.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EWM21156.1 - 0.016 15.3 0.0 0.061 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Cytidylate_kin2 PF13189.1 EWM21156.1 - 0.034 14.0 0.1 0.075 12.9 0.1 1.7 1 1 0 1 1 1 0 Cytidylate kinase-like family AAA_16 PF13191.1 EWM21156.1 - 0.036 14.0 0.0 0.065 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EWM21156.1 - 0.064 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter CPT PF07931.7 EWM21156.1 - 0.068 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_5 PF07728.9 EWM21156.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 EWM21156.1 - 0.13 11.8 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.17 EWM21156.1 - 0.14 11.0 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_32 PF13654.1 EWM21156.1 - 0.14 10.7 0.1 0.28 9.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain PTPS PF01242.14 EWM21157.1 - 2e-19 69.5 0.0 2.6e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase Alkyl_sulf_dimr PF14863.1 EWM21158.1 - 5.3e-30 104.4 0.1 7.8e-30 103.9 0.1 1.3 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.22 EWM21158.1 - 5.5e-06 26.1 0.4 2.8e-05 23.8 0.1 2.1 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Alkyl_sulf_C PF14864.1 EWM21158.1 - 0.00057 19.8 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Ank_4 PF13637.1 EWM21159.1 - 3.9e-29 100.4 6.7 1.6e-08 34.8 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 EWM21159.1 - 5.4e-28 97.1 0.2 3.1e-14 53.0 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EWM21159.1 - 3.4e-26 89.6 0.4 1.1e-06 28.1 0.1 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.1 EWM21159.1 - 5.7e-24 81.7 0.5 4.2e-07 29.5 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 EWM21159.1 - 1.5e-18 66.4 4.0 1.1e-07 31.8 0.7 4.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Fer4 PF00037.22 EWM21160.1 - 3.9e-14 51.5 16.9 1.3e-08 34.0 2.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EWM21160.1 - 2.5e-12 46.9 10.9 3.7e-12 46.4 7.5 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 EWM21160.1 - 3.6e-10 40.4 16.3 5.2e-07 30.3 7.1 2.2 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.1 EWM21160.1 - 1.1e-09 37.9 10.6 1.9e-09 37.1 7.4 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EWM21160.1 - 6.9e-09 35.8 11.2 1.2e-08 35.0 7.7 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 EWM21160.1 - 1.2e-08 34.6 21.8 3e-06 26.9 8.2 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 EWM21160.1 - 1.4e-08 34.1 13.7 0.00013 21.7 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 EWM21160.1 - 5.5e-08 32.3 17.7 0.00064 19.4 3.2 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 EWM21160.1 - 7.6e-08 32.2 19.0 3.7e-06 26.8 7.0 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.2 EWM21160.1 - 5.7e-07 29.3 9.9 0.00021 21.3 1.2 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 EWM21160.1 - 1.4e-05 25.3 9.1 0.0097 16.3 0.6 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.1 EWM21160.1 - 5.5e-05 23.4 10.2 0.00054 20.2 7.5 2.0 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.1 EWM21160.1 - 0.0015 18.8 13.9 0.17 12.2 2.8 2.4 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 EWM21160.1 - 0.0016 18.9 12.3 0.17 12.4 1.0 2.6 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 EWM21160.1 - 0.0033 17.8 17.5 0.0071 16.8 2.8 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 EWM21160.1 - 0.35 11.0 4.8 1.3 9.2 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain UQ_con PF00179.21 EWM21161.1 - 6.1e-27 93.7 0.0 7.8e-27 93.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EWM21161.1 - 0.021 14.7 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 RWD domain WRC PF08879.5 EWM21162.1 - 0.029 14.0 0.8 0.04 13.5 0.0 1.6 2 0 0 2 2 2 0 WRC dCMP_cyt_deam_1 PF00383.17 EWM21163.1 - 9.2e-20 70.1 0.0 1.3e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EWM21163.1 - 0.037 13.6 0.2 0.064 12.8 0.1 1.4 1 0 0 1 1 1 0 APOBEC-like N-terminal domain DUF162 PF02589.10 EWM21163.1 - 0.058 12.9 0.1 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised ACR, YkgG family COG1556 XOO_2897-deam PF14440.1 EWM21163.1 - 0.074 12.7 0.3 0.13 11.9 0.1 1.6 2 0 0 2 2 2 0 Xanthomonas XOO_2897-like deaminase MafB19-deam PF14437.1 EWM21163.1 - 0.11 12.1 0.1 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 MafB19-like deaminase Bd3614-deam PF14439.1 EWM21163.1 - 0.16 11.8 1.0 0.41 10.5 0.6 1.7 1 1 1 2 2 2 0 Bd3614-like deaminase EPL1 PF10513.4 EWM21164.1 - 1.1e-10 42.0 0.0 1.8e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Enhancer of polycomb-like LSM PF01423.17 EWM21166.1 - 1.2e-13 50.3 0.5 1.8e-13 49.8 0.3 1.2 1 0 0 1 1 1 1 LSM domain DEAD PF00270.24 EWM21167.1 - 2.3e-46 157.3 0.0 1.6e-45 154.6 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase GUCT PF08152.7 EWM21167.1 - 1.3e-24 85.9 0.0 2.5e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 GUCT (NUC152) domain Helicase_C PF00271.26 EWM21167.1 - 2.1e-19 69.1 0.1 6.6e-19 67.5 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EWM21167.1 - 2.7e-05 24.0 0.2 0.00015 21.7 0.0 2.3 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EWM21167.1 - 0.022 13.8 0.0 0.022 13.8 0.0 2.7 2 1 1 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.1 EWM21167.1 - 0.022 14.5 0.4 0.12 12.1 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain DsrH PF04077.7 EWM21167.1 - 0.11 12.1 0.1 19 4.9 0.0 2.8 2 0 0 2 2 2 0 DsrH like protein RR_TM4-6 PF06459.7 EWM21167.1 - 3.4 7.4 14.1 5.6 6.7 9.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 WW PF00397.21 EWM21168.1 - 4.1e-20 71.3 7.8 1.6e-10 40.6 0.1 2.6 2 0 0 2 2 2 2 WW domain FYVE PF01363.16 EWM21168.1 - 1.2e-14 53.9 10.3 2e-14 53.1 7.1 1.4 1 0 0 1 1 1 1 FYVE zinc finger Arm PF00514.18 EWM21168.1 - 1.6e-07 30.8 21.5 0.35 10.7 0.1 8.5 9 0 0 9 9 9 3 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EWM21168.1 - 0.0019 18.0 10.7 14 6.0 0.1 6.3 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 EWM21168.1 - 0.047 13.9 24.0 2.1 8.6 0.5 6.3 2 2 4 6 6 6 0 HEAT repeats FYVE_2 PF02318.11 EWM21168.1 - 4.6 7.1 15.5 0.98 9.3 7.7 2.0 2 1 0 2 2 2 0 FYVE-type zinc finger Ribosomal_S2 PF00318.15 EWM21169.1 - 8e-42 142.8 0.0 2.5e-20 72.6 0.0 2.0 1 1 1 2 2 2 2 Ribosomal protein S2 CPSF_A PF03178.10 EWM21170.1 - 1.2e-52 179.0 0.0 1.6e-52 178.6 0.0 1.1 1 0 0 1 1 1 1 CPSF A subunit region Kinesin PF00225.18 EWM21171.1 - 3.2e-85 285.8 0.0 1.2e-84 283.9 0.0 2.0 1 0 0 1 1 1 1 Kinesin motor domain DUF3458 PF11940.3 EWM21173.1 - 6.1e-134 446.4 0.0 1.2e-133 445.4 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3458) Peptidase_M1 PF01433.15 EWM21173.1 - 5.1e-66 223.3 0.0 8.2e-66 222.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 EWM21173.1 - 1.2e-18 67.4 0.2 2.8e-18 66.2 0.1 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 EWM21173.1 - 0.025 14.5 0.0 0.055 13.4 0.0 1.6 1 0 0 1 1 1 0 M61 glycyl aminopeptidase DUF2268 PF10026.4 EWM21173.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) PAP_fibrillin PF04755.7 EWM21174.1 - 7.5e-31 107.4 0.3 7.3e-16 58.4 0.0 2.3 2 0 0 2 2 2 2 PAP_fibrillin Kinesin PF00225.18 EWM21175.1 - 1.3e-88 296.9 0.0 2.1e-88 296.2 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain ERM PF00769.14 EWM21175.1 - 0.00044 19.8 13.5 0.00087 18.8 9.4 1.5 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Macoilin PF09726.4 EWM21175.1 - 0.11 10.7 9.3 0.19 9.9 6.4 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF3584 PF12128.3 EWM21175.1 - 0.19 9.0 23.3 0.27 8.5 16.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_23 PF13476.1 EWM21175.1 - 2.4 8.4 13.6 0.59 10.4 3.2 3.2 3 0 0 3 3 3 0 AAA domain EzrA PF06160.7 EWM21175.1 - 4.3 5.4 16.1 0.11 10.6 5.7 1.8 1 1 0 2 2 2 0 Septation ring formation regulator, EzrA AAA_13 PF13166.1 EWM21175.1 - 4.7 5.5 14.2 28 2.9 9.8 1.9 1 1 0 1 1 1 0 AAA domain TPR_MLP1_2 PF07926.7 EWM21175.1 - 7.1 6.3 21.1 2.2 8.0 8.9 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein MFS_1 PF07690.11 EWM21176.1 - 3.8e-29 101.5 48.9 8e-25 87.2 16.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EWM21176.1 - 1.6e-17 63.0 0.7 4.6e-17 61.5 0.5 1.9 1 0 0 1 1 1 1 MFS_1 like family Nuc_H_symport PF03825.11 EWM21176.1 - 1e-11 44.2 7.6 7.1e-07 28.3 0.9 2.1 2 0 0 2 2 2 2 Nucleoside H+ symporter MFS_2 PF13347.1 EWM21176.1 - 3e-08 32.4 12.7 0.00024 19.6 2.5 2.9 1 1 2 3 3 3 2 MFS/sugar transport protein LacY_symp PF01306.14 EWM21176.1 - 7.9e-05 21.3 1.9 7.9e-05 21.3 1.3 2.0 2 0 0 2 2 2 1 LacY proton/sugar symporter ATG22 PF11700.3 EWM21176.1 - 0.014 13.8 0.2 0.014 13.8 0.1 2.6 2 1 1 3 3 3 0 Vacuole effluxer Atg22 like E1-E2_ATPase PF00122.15 EWM21177.1 - 1.3e-52 178.1 2.2 1.3e-52 178.1 1.5 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EWM21177.1 - 1.4e-26 94.2 0.1 3.2e-26 93.0 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EWM21177.1 - 4.7e-13 49.7 0.0 1e-12 48.6 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EWM21177.1 - 4.8e-12 45.1 0.1 3.4e-11 42.4 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EWM21177.1 - 3.6e-05 23.4 0.5 0.00025 20.7 0.0 2.4 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EWM21177.1 - 0.18 11.8 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Met_10 PF02475.11 EWM21178.1 - 1.4e-45 155.3 0.1 1.2e-28 100.1 0.0 2.1 1 1 1 2 2 2 2 Met-10+ like-protein Methyltransf_18 PF12847.2 EWM21178.1 - 0.042 14.4 0.0 0.095 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.5 EWM21178.1 - 0.22 11.0 0.0 0.38 10.2 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase MethyltransfD12 PF02086.10 EWM21178.1 - 0.24 10.8 0.0 0.38 10.1 0.0 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase zf-C2H2_4 PF13894.1 EWM21178.1 - 0.49 10.8 3.4 0.72 10.3 0.9 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Sulfatase PF00884.18 EWM21179.1 - 3.8e-59 200.3 0.0 5.5e-59 199.8 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EWM21179.1 - 0.00033 20.0 0.0 0.055 12.7 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.7 EWM21179.1 - 0.00065 18.6 0.0 0.0011 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) UPF0542 PF15086.1 EWM21179.1 - 0.013 15.2 0.1 0.039 13.6 0.1 1.9 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 Sulfatase PF00884.18 EWM21180.1 - 2.4e-59 201.0 0.0 3.3e-59 200.5 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EWM21180.1 - 0.00021 20.7 0.0 0.04 13.2 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1501 PF07394.7 EWM21180.1 - 0.00049 19.0 0.0 0.00084 18.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) Choline_transpo PF04515.7 EWM21181.1 - 2.1e-65 220.6 26.9 2.1e-65 220.6 18.7 2.0 2 0 0 2 2 2 1 Plasma-membrane choline transporter LRR_6 PF13516.1 EWM21182.1 - 0.00046 19.9 1.1 1.2 9.4 0.0 3.7 3 0 0 3 3 3 1 Leucine Rich repeat Ank_2 PF12796.2 EWM21182.1 - 0.0023 18.2 0.0 0.025 14.8 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Meckelin PF09773.4 EWM21182.1 - 0.048 11.4 0.5 0.074 10.8 0.0 1.4 2 0 0 2 2 2 0 Meckelin (Transmembrane protein 67) Ank PF00023.25 EWM21182.1 - 0.053 13.3 0.1 2.6 7.9 0.1 2.9 3 0 0 3 3 3 0 Ankyrin repeat PhaG_MnhG_YufB PF03334.9 EWM21183.1 - 0.014 15.4 0.8 0.02 14.8 0.5 1.2 1 0 0 1 1 1 0 Na+/H+ antiporter subunit Helicase_C PF00271.26 EWM21188.1 - 1.5e-09 37.6 0.0 2.5e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.18 EWM21188.1 - 1.6e-09 37.7 0.0 3.4e-09 36.6 0.0 1.5 1 1 0 1 1 1 1 Helicase associated domain (HA2) BOP1NT PF08145.7 EWM21190.1 - 1.2e-35 123.5 0.0 1.6e-35 123.1 0.0 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain DUF2457 PF10446.4 EWM21190.1 - 0.13 10.9 14.1 0.16 10.6 9.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) WD40 PF00400.27 EWM21191.1 - 4e-25 86.7 2.5 1.5e-07 31.0 0.0 5.6 4 2 2 6 6 6 5 WD domain, G-beta repeat PQQ_3 PF13570.1 EWM21191.1 - 0.12 12.6 0.4 9.3 6.6 0.0 3.4 3 0 0 3 3 3 0 PQQ-like domain TPR_1 PF00515.23 EWM21192.1 - 9.5e-11 40.8 5.9 2e-05 23.9 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EWM21192.1 - 5.8e-09 35.4 25.8 9.9e-08 31.5 3.5 3.4 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.12 EWM21192.1 - 3.1e-08 32.9 8.4 8.7e-05 22.1 0.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EWM21192.1 - 3.8e-08 33.7 1.8 3.8e-08 33.7 1.2 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EWM21192.1 - 6.3e-05 23.0 4.0 6.3e-05 23.0 2.8 1.9 2 0 0 2 2 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EWM21192.1 - 0.00016 21.6 1.3 0.0015 18.5 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EWM21192.1 - 0.00022 21.5 1.1 0.00078 19.7 0.8 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 EWM21192.1 - 0.00029 20.6 7.8 0.00076 19.3 1.3 3.4 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_20 PF14561.1 EWM21192.1 - 0.00073 19.6 0.9 0.0016 18.4 0.6 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 EWM21192.1 - 0.00086 18.9 2.0 0.036 13.8 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EWM21192.1 - 0.025 15.1 9.2 0.029 14.9 1.1 3.8 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EWM21192.1 - 0.032 14.1 6.8 4.6 7.3 0.1 4.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EWM21192.1 - 0.066 13.0 2.9 0.091 12.6 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EWM21192.1 - 0.071 12.9 1.1 9.7 6.1 0.1 2.7 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.9 EWM21192.1 - 0.18 12.3 0.1 0.18 12.3 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EWM21192.1 - 0.28 11.7 0.2 0.28 11.7 0.2 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat DnaJ PF00226.26 EWM21194.1 - 4.7e-20 71.0 0.0 1.2e-19 69.8 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.17 EWM21194.1 - 9.3e-06 25.1 0.0 0.00019 20.9 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.1 EWM21194.1 - 0.00033 20.2 0.0 0.00059 19.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4523) RRM_6 PF14259.1 EWM21194.1 - 0.0079 16.1 0.0 0.26 11.2 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM21194.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M16 PF00675.15 EWM21194.1 - 0.13 12.0 1.6 0.21 11.3 0.1 1.9 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) Smr PF01713.16 EWM21198.1 - 1.5e-05 25.1 0.0 3.1e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Smr domain PPR_1 PF12854.2 EWM21198.1 - 0.00033 20.0 0.2 0.0065 15.9 0.0 2.4 2 0 0 2 2 2 1 PPR repeat PPR PF01535.15 EWM21198.1 - 0.00051 19.8 0.2 0.01 15.7 0.0 2.6 2 0 0 2 2 2 1 PPR repeat TPR_16 PF13432.1 EWM21198.1 - 0.0098 16.5 0.2 0.029 15.0 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat PPR_2 PF13041.1 EWM21198.1 - 0.15 12.0 0.0 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 PPR repeat family PPR_3 PF13812.1 EWM21198.1 - 0.24 11.7 1.8 1.9 8.9 0.0 3.2 3 0 0 3 3 3 0 Pentatricopeptide repeat domain HECT PF00632.20 EWM21199.1 - 3.6e-13 49.3 0.0 4.2e-13 49.1 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) PHD PF00628.24 EWM21200.1 - 4.1e-05 23.1 2.7 7.2e-05 22.4 1.9 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EWM21200.1 - 0.084 12.2 5.9 0.16 11.2 4.1 1.4 1 0 0 1 1 1 0 PHD-finger SDA1 PF05285.7 EWM21200.1 - 0.13 11.5 9.3 0.19 10.9 6.5 1.4 1 0 0 1 1 1 0 SDA1 TFIIA PF03153.8 EWM21200.1 - 2.2 8.1 5.5 2.7 7.7 3.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 EWM21200.1 - 6.8 4.4 15.4 8.7 4.1 10.7 1.1 1 0 0 1 1 1 0 Nop14-like family DAO PF01266.19 EWM21201.1 - 3.2e-06 26.3 0.9 8.4e-05 21.6 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EWM21201.1 - 0.0001 22.2 0.2 0.00025 20.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EWM21201.1 - 0.00012 21.1 0.1 0.0013 17.7 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EWM21201.1 - 0.0039 16.0 0.2 0.0049 15.7 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EWM21201.1 - 0.0056 15.7 2.6 0.29 10.1 0.2 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 EWM21201.1 - 0.0058 15.7 0.0 0.01 14.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EWM21201.1 - 0.012 15.5 0.1 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EWM21201.1 - 0.05 12.2 0.0 0.057 12.0 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.1 EWM21201.1 - 0.061 13.1 0.6 0.19 11.4 0.0 2.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding Mqo PF06039.10 EWM21201.1 - 0.19 9.8 0.0 0.25 9.4 0.0 1.1 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) 60KD_IMP PF02096.15 EWM21207.1 - 3.4e-05 23.5 0.0 3.8e-05 23.4 0.0 1.0 1 0 0 1 1 1 1 60Kd inner membrane protein Dmrt1 PF12374.3 EWM21208.1 - 0.12 12.7 11.7 0.22 11.8 8.1 1.4 1 0 0 1 1 1 0 Double-sex mab3 related transcription factor 1 Sporozoite_P67 PF05642.6 EWM21208.1 - 0.49 8.1 7.4 0.56 8.0 5.2 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Herpes_capsid PF06112.6 EWM21208.1 - 0.67 9.9 18.4 0.83 9.6 12.8 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein zf-GRF PF06839.7 EWM21209.1 - 2.2e-08 33.8 5.7 3.5e-08 33.2 4.0 1.3 1 0 0 1 1 1 1 GRF zinc finger Zn_Tnp_IS1595 PF12760.2 EWM21209.1 - 0.15 11.8 2.0 0.35 10.7 1.4 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain NUDIX PF00293.23 EWM21211.1 - 1.4e-13 50.6 0.1 2.1e-13 50.0 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain MaoC_dehydrat_N PF13452.1 EWM21211.1 - 0.11 12.3 0.1 0.27 11.0 0.1 1.6 1 0 0 1 1 1 0 N-terminal half of MaoC dehydratase Peptidase_A22B PF04258.8 EWM21213.1 - 2e-12 47.1 0.0 6.2e-09 35.7 0.0 2.1 2 0 0 2 2 2 2 Signal peptide peptidase Peptidase_A22B PF04258.8 EWM21214.1 - 2e-12 47.1 0.0 6.2e-09 35.7 0.0 2.1 2 0 0 2 2 2 2 Signal peptide peptidase PseudoU_synth_2 PF00849.17 EWM21217.1 - 1e-05 25.4 0.3 1.6e-05 24.7 0.2 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase PT PF04886.7 EWM21220.1 - 0.00016 20.9 9.4 0.00016 20.9 6.5 1.9 2 0 0 2 2 2 1 PT repeat S4 PF01479.20 EWM21221.1 - 4.7e-09 35.5 0.2 8.8e-09 34.6 0.1 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 EWM21221.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 S4 domain PAP_fibrillin PF04755.7 EWM21222.1 - 5.8e-08 32.6 0.1 0.0019 17.9 0.1 2.7 2 1 0 2 2 2 2 PAP_fibrillin DUF702 PF05142.7 EWM21223.1 - 3.6 7.7 8.4 4 7.5 5.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF702) TFIIF_alpha PF05793.7 EWM21224.1 - 0.63 8.3 51.8 0.95 7.7 35.9 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Trigger_N PF05697.8 EWM21225.1 - 3.3e-05 23.7 0.0 6.3e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 Bacterial trigger factor protein (TF) Methyltransf_16 PF10294.4 EWM21226.1 - 0.13 11.7 0.1 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PX PF00787.19 EWM21227.1 - 9.8e-09 35.0 0.0 1.5e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 PX domain Retrotrans_gag PF03732.12 EWM21228.1 - 0.1 12.6 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Retrotransposon gag protein Ndc1_Nup PF09531.5 EWM21229.1 - 1.4 7.2 6.1 1.7 6.9 4.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Birna_RdRp PF04197.7 EWM21229.1 - 1.5 6.7 13.4 1.7 6.5 9.3 1.0 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) Rrn6 PF10214.4 EWM21229.1 - 2.1 6.3 11.2 2.4 6.1 7.8 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Beta-lactamase PF00144.19 EWM21231.1 - 1.3e-48 165.7 0.0 1.8e-48 165.3 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase BT1 PF03092.11 EWM21233.1 - 7.9e-08 31.4 0.4 9.7e-08 31.1 0.3 1.1 1 0 0 1 1 1 1 BT1 family MFS_3 PF05977.8 EWM21233.1 - 0.13 10.3 2.9 0.14 10.2 2.0 1.1 1 0 0 1 1 1 0 Transmembrane secretion effector GMC_oxred_N PF00732.14 EWM21237.1 - 5e-17 61.9 0.1 5.4e-17 61.8 0.1 1.0 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.9 EWM21237.1 - 2.4e-05 24.2 0.0 2.8e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EWM21237.1 - 9.8e-05 21.4 0.1 0.00013 21.0 0.1 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EWM21237.1 - 0.00011 21.2 1.1 0.00011 21.2 0.8 1.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EWM21237.1 - 0.00011 22.1 0.5 0.00025 21.0 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EWM21237.1 - 0.00011 21.1 0.9 0.00015 20.7 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EWM21237.1 - 0.00015 21.8 0.1 0.00017 21.7 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EWM21237.1 - 0.00072 19.9 0.0 0.00099 19.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EWM21237.1 - 0.0015 18.6 0.0 0.0021 18.1 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EWM21237.1 - 0.0021 17.1 0.1 0.003 16.6 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.11 EWM21237.1 - 0.0042 16.5 0.1 0.0051 16.2 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 EWM21237.1 - 0.0053 16.7 0.0 0.0068 16.4 0.0 1.2 1 0 0 1 1 1 1 TrkA-N domain HI0933_like PF03486.9 EWM21237.1 - 0.0069 14.9 0.3 0.0083 14.6 0.2 1.1 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EWM21237.1 - 0.015 14.4 0.1 0.02 14.0 0.0 1.1 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 EWM21237.1 - 0.018 14.8 0.8 0.026 14.3 0.6 1.6 1 1 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.17 EWM21237.1 - 0.029 13.2 0.2 0.035 12.9 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 EWM21237.1 - 0.049 13.3 0.3 0.095 12.4 0.1 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ThiF PF00899.16 EWM21237.1 - 0.063 13.1 0.7 0.12 12.1 0.4 1.5 1 1 1 2 2 2 0 ThiF family KOW PF00467.24 EWM21237.1 - 0.14 11.9 1.6 0.34 10.7 1.1 1.6 1 0 0 1 1 1 0 KOW motif F420_oxidored PF03807.12 EWM21237.1 - 0.23 11.8 0.8 0.24 11.8 0.0 1.5 2 0 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent FAD_oxidored PF12831.2 EWM21237.1 - 1.8 7.5 4.7 0.66 8.9 1.6 1.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF1325 PF07039.6 EWM21243.1 - 1e-17 63.9 0.1 2e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 SGF29 tudor-like domain ING PF12998.2 EWM21243.1 - 4.1e-15 55.9 3.9 5.8e-15 55.4 2.7 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding Aminotran_1_2 PF00155.16 EWM21247.1 - 0.091 11.6 0.0 0.11 11.4 0.0 1.0 1 0 0 1 1 1 0 Aminotransferase class I and II MutS_V PF00488.16 EWM21249.1 - 2.5e-89 298.7 0.0 3.4e-89 298.2 0.0 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EWM21249.1 - 2.7e-10 40.3 0.1 9e-10 38.6 0.0 1.8 1 1 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 EWM21249.1 - 1e-07 32.0 0.1 2e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.1 EWM21249.1 - 0.046 13.2 0.0 0.15 11.5 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain HALZ PF02183.13 EWM21254.1 - 0.028 14.1 2.3 0.042 13.5 0.2 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper Reo_sigmaC PF04582.7 EWM21254.1 - 0.63 9.1 7.0 0.34 10.0 2.1 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF641 PF04859.7 EWM21254.1 - 3.5 7.3 18.5 6.2 6.5 0.1 3.6 1 1 2 4 4 4 0 Plant protein of unknown function (DUF641) V_ATPase_I PF01496.14 EWM21254.1 - 5.6 4.6 9.3 7 4.3 6.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lebercilin PF15619.1 EWM21254.1 - 6.5 6.1 24.0 5.3 6.4 12.7 2.7 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Cortex-I_coil PF09304.5 EWM21254.1 - 8.8 6.4 24.1 0.72 9.9 9.8 2.5 1 1 1 2 2 2 0 Cortexillin I, coiled coil SBP_bac_3 PF00497.15 EWM21255.1 - 4.1e-10 39.2 0.0 5.7e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 SBP_bac_3 PF00497.15 EWM21256.1 - 3.7e-05 23.0 0.0 3.8e-05 23.0 0.0 1.0 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Daxx PF03344.10 EWM21257.1 - 0.0042 15.6 13.2 0.0042 15.6 9.2 1.4 2 0 0 2 2 2 1 Daxx Family Nop14 PF04147.7 EWM21257.1 - 0.014 13.4 8.4 0.016 13.1 5.8 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 EWM21257.1 - 0.039 13.2 9.3 0.05 12.8 6.5 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.5 EWM21257.1 - 0.046 12.7 6.3 0.06 12.4 4.3 1.2 1 0 0 1 1 1 0 BUD22 TRAP_alpha PF03896.11 EWM21257.1 - 0.061 12.3 4.2 0.093 11.7 2.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Vfa1 PF08432.5 EWM21257.1 - 0.23 11.4 2.5 0.31 11.0 1.8 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CENP-B_dimeris PF09026.5 EWM21257.1 - 0.23 11.7 15.9 0.4 10.9 11.0 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Tim54 PF11711.3 EWM21257.1 - 0.26 9.8 2.9 0.31 9.5 2.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RNA_pol_3_Rpc31 PF11705.3 EWM21257.1 - 0.68 9.8 13.2 0.88 9.4 9.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF3306 PF11748.3 EWM21257.1 - 1.9 9.1 8.6 0.61 10.7 4.1 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF3306) Pox_Ag35 PF03286.9 EWM21257.1 - 2.1 7.8 7.0 1.1 8.7 3.7 1.5 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Sigma70_ner PF04546.8 EWM21257.1 - 2.1 7.8 13.2 3.1 7.3 9.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region SspB PF04386.8 EWM21257.1 - 3 7.4 6.2 4.5 6.8 4.3 1.2 1 0 0 1 1 1 0 Stringent starvation protein B Nucleoplasmin PF03066.10 EWM21257.1 - 3.9 6.9 19.2 7.2 6.1 13.3 1.4 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 EWM21257.1 - 4.3 6.5 6.9 6.1 6.0 4.8 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 EWM21257.1 - 4.4 5.2 8.0 5.6 4.8 5.5 1.1 1 0 0 1 1 1 0 CDC45-like protein VID27 PF08553.5 EWM21257.1 - 4.6 5.3 10.1 5.7 5.0 7.0 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Mpp10 PF04006.7 EWM21257.1 - 5.4 5.2 15.4 7.2 4.8 10.7 1.1 1 0 0 1 1 1 0 Mpp10 protein EBV-NA3 PF05009.7 EWM21257.1 - 5.8 6.0 5.6 7.9 5.6 3.9 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Radial_spoke PF04712.7 EWM21257.1 - 7 5.2 15.8 9.2 4.8 10.9 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Prothymosin PF03247.9 EWM21257.1 - 8.6 6.5 32.1 14 5.8 22.2 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family PWI PF01480.12 EWM21258.1 - 0.019 15.0 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 PWI domain Mito_fiss_reg PF05308.6 EWM21259.1 - 0.8 9.0 5.0 0.89 8.8 3.4 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Sensor_TM1 PF13755.1 EWM21261.1 - 0.014 14.8 0.5 0.021 14.3 0.3 1.4 1 0 0 1 1 1 0 Sensor N-terminal transmembrane domain AflR PF08493.5 EWM21261.1 - 0.059 12.4 0.1 0.07 12.1 0.1 1.1 1 0 0 1 1 1 0 Aflatoxin regulatory protein DUF1237 PF06824.6 EWM21262.1 - 6e-40 137.1 0.0 3.6e-39 134.5 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1237) PEPcase PF00311.12 EWM21263.1 - 8.2 4.1 5.5 11 3.7 3.8 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase LRR_6 PF13516.1 EWM21264.1 - 3.2e-18 63.6 0.4 0.013 15.4 0.0 7.6 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.2 EWM21264.1 - 3.5e-09 36.0 0.2 0.0013 18.2 0.2 4.0 2 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EWM21264.1 - 1.2e-07 30.7 0.7 0.47 10.6 0.0 5.2 6 0 0 6 6 5 2 Leucine Rich Repeat LRR_8 PF13855.1 EWM21264.1 - 0.00026 20.6 4.8 0.018 14.7 0.8 4.3 2 1 2 4 4 4 3 Leucine rich repeat LRR_7 PF13504.1 EWM21264.1 - 0.0004 20.1 7.0 0.72 10.2 0.0 5.2 6 0 0 6 6 5 1 Leucine rich repeat CENP-T PF15511.1 EWM21264.1 - 0.011 14.9 8.7 0.014 14.6 6.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Nop14 PF04147.7 EWM21264.1 - 0.012 13.6 19.9 0.014 13.3 13.8 1.1 1 0 0 1 1 1 0 Nop14-like family DDHD PF02862.12 EWM21264.1 - 0.076 12.7 3.5 0.11 12.3 2.4 1.3 1 0 0 1 1 1 0 DDHD domain RAB3GAP2_C PF14656.1 EWM21264.1 - 0.24 9.5 4.3 0.32 9.0 3.0 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus Sigma70_ner PF04546.8 EWM21264.1 - 0.55 9.8 22.1 0.85 9.1 15.3 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Merozoite_SPAM PF07133.6 EWM21264.1 - 0.58 10.0 34.3 0.93 9.3 23.7 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) SDA1 PF05285.7 EWM21264.1 - 0.6 9.3 20.3 0.93 8.7 14.1 1.3 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 EWM21264.1 - 0.73 8.2 26.8 0.94 7.8 18.5 1.1 1 0 0 1 1 1 0 Daxx Family TFIIA PF03153.8 EWM21264.1 - 0.91 9.3 10.7 1.1 9.1 7.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1510 PF07423.6 EWM21264.1 - 0.97 8.7 17.9 1.4 8.2 12.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) BUD22 PF09073.5 EWM21264.1 - 1.4 7.9 19.4 2 7.3 13.4 1.2 1 0 0 1 1 1 0 BUD22 Tim54 PF11711.3 EWM21264.1 - 2.5 6.6 10.6 3.8 5.9 7.3 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.9 EWM21264.1 - 2.9 5.8 17.8 3.9 5.3 12.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.17 EWM21264.1 - 3.3 6.6 4.6 4.2 6.2 3.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CobT PF06213.7 EWM21264.1 - 4 6.5 24.8 6.3 5.8 17.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Paf1 PF03985.8 EWM21264.1 - 6 5.4 24.9 8.3 5.0 17.3 1.1 1 0 0 1 1 1 0 Paf1 Vfa1 PF08432.5 EWM21264.1 - 9.3 6.2 12.7 15 5.5 8.8 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 L51_S25_CI-B8 PF05047.11 EWM21265.1 - 8.6e-05 22.2 0.1 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MRP_L53 PF10780.4 EWM21265.1 - 0.00046 20.0 0.0 0.00082 19.3 0.0 1.4 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Glyco_transf_10 PF00852.14 EWM21269.1 - 3.9e-29 101.3 0.0 5.3e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) SNF2_N PF00176.18 EWM21270.1 - 1.7e-28 99.2 0.0 2.2e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EWM21270.1 - 0.17 11.4 0.0 0.23 10.9 0.0 1.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase Kua-UEV1_localn PF10520.4 EWM21272.1 - 5.7e-12 45.6 1.7 8.9e-12 45.0 1.2 1.3 1 0 0 1 1 1 1 Kua-ubiquitin conjugating enzyme hybrid localisation domain Choline_kinase PF01633.15 EWM21273.1 - 5.8e-41 140.3 0.0 1.4e-40 139.1 0.0 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EWM21273.1 - 7.8e-06 25.7 0.1 0.022 14.5 0.0 2.4 2 1 0 2 2 2 2 Phosphotransferase enzyme family IATP PF04568.7 EWM21275.1 - 5.8e-06 26.2 2.0 8.1e-06 25.8 1.4 1.4 1 1 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP TRH PF05438.7 EWM21275.1 - 0.01 15.2 0.1 0.012 14.9 0.1 1.1 1 0 0 1 1 1 0 Thyrotropin-releasing hormone (TRH) Esterase PF00756.15 EWM21276.1 - 3.6e-48 164.1 0.0 4.5e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EWM21276.1 - 1.7e-06 27.8 0.1 2.5e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EWM21276.1 - 0.00047 19.1 0.0 0.00065 18.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme DLH PF01738.13 EWM21276.1 - 0.17 11.1 1.4 2.5 7.3 0.1 2.4 2 1 0 2 2 2 0 Dienelactone hydrolase family EF-hand_1 PF00036.27 EWM21277.1 - 4.2e-25 85.1 9.0 9.3e-08 30.8 0.1 4.5 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 EWM21277.1 - 1.9e-23 82.3 9.4 2.5e-11 43.5 1.5 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EWM21277.1 - 3.8e-21 74.4 12.3 5.8e-11 41.8 0.6 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EWM21277.1 - 6.1e-20 69.2 9.5 2.3e-08 33.2 0.1 4.4 4 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 EWM21277.1 - 1e-09 37.2 10.8 0.00011 21.3 0.2 4.7 5 1 0 5 5 4 3 EF hand EF-hand_9 PF14658.1 EWM21277.1 - 3e-09 36.6 0.2 0.00016 21.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain Caleosin PF05042.8 EWM21277.1 - 0.0002 20.9 0.3 0.2 11.1 0.0 3.0 2 1 1 3 3 3 1 Caleosin related protein SPARC_Ca_bdg PF10591.4 EWM21277.1 - 0.01 15.8 0.5 4.8 7.2 0.1 2.3 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region MerR-DNA-bind PF09278.6 EWM21277.1 - 0.016 15.5 0.2 4.4 7.7 0.0 3.4 1 1 2 3 3 3 0 MerR, DNA binding EF-hand_like PF09279.6 EWM21277.1 - 0.016 15.2 0.7 0.29 11.1 0.1 2.7 2 1 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_4 PF12763.2 EWM21277.1 - 0.021 14.5 0.6 0.021 14.5 0.5 2.7 2 1 0 3 3 2 0 Cytoskeletal-regulatory complex EF hand Acetyltransf_11 PF13720.1 EWM21277.1 - 0.025 14.7 1.0 1.3 9.2 0.1 2.6 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 PMBR PF09373.5 EWM21277.1 - 0.12 12.4 0.0 2.6 8.1 0.0 3.0 3 0 0 3 3 3 0 Pseudomurein-binding repeat Toprim_2 PF13155.1 EWM21277.1 - 0.12 12.7 0.5 18 5.7 0.0 2.3 1 1 1 2 2 2 0 Toprim-like IF2_N PF04760.10 EWM21277.1 - 0.23 11.1 2.2 3.8 7.2 0.0 3.1 3 1 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region TerB PF05099.8 EWM21277.1 - 1.3 8.7 8.8 7.4 6.2 0.9 3.0 1 1 1 3 3 3 0 Tellurite resistance protein TerB ComC PF03047.9 EWM21277.1 - 1.8 8.0 6.5 12 5.4 0.9 2.4 2 0 0 2 2 2 0 COMC family EF-hand_10 PF14788.1 EWM21277.1 - 2.5 7.8 5.0 8.5 6.1 0.2 3.3 3 1 1 4 4 4 0 EF hand ELO PF01151.13 EWM21280.1 - 1.1e-44 152.6 8.2 1.3e-44 152.3 5.7 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family TraL PF07178.6 EWM21280.1 - 0.21 11.6 0.1 0.21 11.6 0.1 2.1 2 1 0 2 2 2 0 TraL protein PP2C PF00481.16 EWM21282.1 - 4.8e-66 222.7 1.1 3e-53 180.8 0.3 3.2 2 1 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EWM21282.1 - 1.4e-06 27.8 0.0 5.6e-06 25.9 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C Rhabdo_ncap PF00945.13 EWM21282.1 - 1.1 7.7 8.9 0.093 11.3 2.7 1.6 2 0 0 2 2 2 0 Rhabdovirus nucleocapsid protein PP2C PF00481.16 EWM21283.1 - 6.2e-66 222.3 1.1 3.4e-53 180.6 0.3 3.1 2 1 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EWM21283.1 - 1.7e-06 27.5 0.0 6.6e-06 25.6 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C Rhabdo_ncap PF00945.13 EWM21283.1 - 1.3 7.5 8.9 0.1 11.1 2.7 1.6 2 0 0 2 2 2 0 Rhabdovirus nucleocapsid protein Acetyltransf_1 PF00583.19 EWM21284.1 - 2.4e-06 27.5 0.0 5.1e-05 23.2 0.0 2.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EWM21284.1 - 0.0015 18.6 0.0 0.0066 16.5 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EWM21284.1 - 0.0032 17.3 0.0 0.37 10.6 0.0 2.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EWM21284.1 - 0.072 12.8 0.1 6.2 6.6 0.0 2.3 2 0 0 2 2 2 0 FR47-like protein Glyoxalase_2 PF12681.2 EWM21285.1 - 3.7e-08 33.9 0.0 7.9e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EWM21285.1 - 0.0001 22.2 0.4 0.00038 20.4 0.3 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MttA_Hcf106 PF02416.11 EWM21287.1 - 3.6e-08 32.3 0.7 5.5e-08 31.8 0.5 1.4 1 0 0 1 1 1 1 mttA/Hcf106 family FGF-BP1 PF06473.7 EWM21287.1 - 0.018 14.6 0.5 0.025 14.1 0.4 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) AAA_2 PF07724.9 EWM21292.1 - 1.3e-11 44.7 0.0 1.6e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Dispanin PF04505.7 EWM21293.1 - 0.061 12.8 0.1 0.19 11.2 0.0 1.8 2 0 0 2 2 2 0 Interferon-induced transmembrane protein ClpB_D2-small PF10431.4 EWM21294.1 - 1e-14 54.1 0.0 1.4e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein UPF1_Zn_bind PF09416.5 EWM21295.1 - 4.7e-71 237.3 1.3 4.7e-71 237.3 0.9 2.0 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_11 PF13086.1 EWM21295.1 - 3.6e-54 183.8 1.0 5.9e-54 183.1 0.7 1.3 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 EWM21295.1 - 8.2e-26 90.6 0.0 1.6e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EWM21295.1 - 2.7e-14 52.6 0.5 7.3e-14 51.2 0.3 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EWM21295.1 - 1.7e-13 50.5 2.8 4e-12 46.1 0.2 3.0 2 1 0 2 2 2 1 AAA domain ResIII PF04851.10 EWM21295.1 - 5.9e-07 29.5 0.1 3.4e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 EWM21295.1 - 1.3e-06 27.9 0.1 0.00089 18.6 0.0 2.7 3 0 0 3 3 3 2 UvrD/REP helicase N-terminal domain DUF2075 PF09848.4 EWM21295.1 - 0.00044 19.3 0.1 0.0012 17.9 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.9 EWM21295.1 - 0.00054 19.6 0.0 0.00099 18.7 0.0 1.6 1 0 0 1 1 1 1 Helicase PIF1 PF05970.9 EWM21295.1 - 0.00065 18.7 0.1 0.55 9.1 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase Flavi_DEAD PF07652.9 EWM21295.1 - 0.0051 16.5 0.1 0.011 15.5 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain SNF2_N PF00176.18 EWM21295.1 - 0.0094 14.7 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_16 PF13191.1 EWM21295.1 - 0.0098 15.8 0.1 0.024 14.6 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain PhoH PF02562.11 EWM21295.1 - 0.011 14.9 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_10 PF12846.2 EWM21295.1 - 0.013 14.9 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_25 PF13481.1 EWM21295.1 - 0.014 14.8 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 EWM21295.1 - 0.018 14.5 0.2 0.036 13.5 0.1 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase KaiC PF06745.8 EWM21295.1 - 0.031 13.3 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 EWM21295.1 - 0.081 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA PF00004.24 EWM21295.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EWM21295.1 - 0.12 11.1 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Shikimate_DH PF01488.15 EWM21295.1 - 0.17 11.9 0.0 3.1 7.8 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FadA PF09403.5 EWM21295.1 - 0.53 10.2 2.5 0.81 9.7 0.0 2.1 2 0 0 2 2 2 0 Adhesion protein FadA CybS PF05328.7 EWM21298.1 - 1.1e-14 54.1 0.0 1.4e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 CybS Sdh_cyt PF01127.17 EWM21298.1 - 0.1 12.4 0.1 0.17 11.7 0.1 1.4 1 1 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit ARID PF01388.16 EWM21300.1 - 9.1e-09 35.0 0.0 1.4e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjC PF02373.17 EWM21302.1 - 2.9e-20 72.5 0.0 5.5e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 EWM21302.1 - 4e-05 23.2 3.3 7.8e-05 22.2 2.3 1.5 1 1 0 1 1 1 1 PHD-finger C1_1 PF00130.17 EWM21302.1 - 0.021 14.5 0.4 0.049 13.3 0.3 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Microcephalin PF12258.3 EWM21302.1 - 0.079 11.9 0.7 0.12 11.3 0.5 1.1 1 0 0 1 1 1 0 Microcephalin protein dUTPase PF00692.14 EWM21304.1 - 5.5e-37 126.1 0.0 8.2e-37 125.5 0.0 1.3 1 0 0 1 1 1 1 dUTPase DUF3133 PF11331.3 EWM21304.1 - 0.1 12.1 0.5 0.19 11.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3133) DUF2273 PF10031.4 EWM21306.1 - 0.17 11.5 0.0 0.17 11.5 0.0 2.2 3 0 0 3 3 3 0 Small integral membrane protein (DUF2273) DUF2975 PF11188.3 EWM21306.1 - 0.61 9.8 6.3 7.4 6.2 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) DUF2189 PF09955.4 EWM21306.1 - 0.76 9.7 0.1 0.76 9.7 0.0 3.5 3 1 0 3 3 3 0 Predicted integral membrane protein (DUF2189) UPF0020 PF01170.13 EWM21307.1 - 2.5e-15 56.4 0.0 5e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EWM21307.1 - 3e-12 46.6 0.7 8.3e-12 45.1 0.1 2.0 2 1 0 2 2 2 1 Methyltransferase domain N6_N4_Mtase PF01555.13 EWM21307.1 - 4.2e-06 26.4 0.0 4.2e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 DNA methylase N6_Mtase PF02384.11 EWM21307.1 - 0.0035 16.4 0.0 0.0053 15.8 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_10 PF05971.7 EWM21307.1 - 0.1 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF890) Cys_Met_Meta_PP PF01053.15 EWM21308.1 - 2.9e-79 266.1 0.0 3.7e-79 265.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Glyco_transf_7C PF02709.9 EWM21309.1 - 4.1e-20 71.0 0.1 6.8e-20 70.3 0.1 1.3 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.1 EWM21309.1 - 4.2e-10 39.1 0.6 9.3e-07 28.2 0.1 3.0 2 1 0 2 2 2 2 N-terminal region of glycosyl transferase group 7 Glyco_tranf_2_2 PF10111.4 EWM21309.1 - 2.4e-05 23.5 0.0 0.00052 19.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Lon_C PF05362.8 EWM21310.1 - 4.3e-43 147.0 13.0 2.8e-35 121.5 2.0 3.9 3 1 0 3 3 3 3 Lon protease (S16) C-terminal proteolytic domain ChlI PF13541.1 EWM21310.1 - 4e-05 23.1 0.3 0.00026 20.4 0.1 2.1 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase DUF399 PF04187.8 EWM21311.1 - 1.7e-25 89.8 0.0 2.7e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF399 SAM_decarbox PF01536.11 EWM21312.1 - 9.8e-96 320.2 0.0 1.3e-95 319.8 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Ribosomal_60s PF00428.14 EWM21312.1 - 5.3 7.5 13.1 5.8 7.3 8.0 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein ABC1 PF03109.11 EWM21313.1 - 6.3e-29 100.3 0.1 1.1e-28 99.5 0.1 1.4 1 0 0 1 1 1 1 ABC1 family DUF2009 PF09418.5 EWM21314.1 - 1e-142 476.2 0.0 1.8e-110 369.8 0.0 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF2009) zf-B_box PF00643.19 EWM21314.1 - 0.00011 22.0 3.6 0.00018 21.3 2.5 1.3 1 0 0 1 1 1 1 B-box zinc finger zf-UDP PF14569.1 EWM21314.1 - 0.14 11.9 2.6 0.92 9.3 1.3 2.4 2 0 0 2 2 2 0 Zinc-binding RING-finger C1_4 PF07975.7 EWM21314.1 - 6.7 6.8 8.4 87 3.2 5.8 2.2 1 1 0 1 1 1 0 TFIIH C1-like domain Aldedh PF00171.17 EWM21315.1 - 4.1e-151 503.4 0.0 6.1e-110 367.7 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Ribosomal_L34 PF00468.12 EWM21315.1 - 0.063 12.9 0.8 0.25 11.0 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L34 Cullin PF00888.17 EWM21316.1 - 7.1e-25 87.5 0.0 1.3e-24 86.7 0.0 1.3 2 0 0 2 2 2 1 Cullin family APC2 PF08672.6 EWM21316.1 - 5.3e-05 23.3 0.0 9.2e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 DUF1356 PF07092.7 EWM21317.1 - 8.1e-07 28.4 0.0 1.2e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) Chol_subst-bind PF09129.6 EWM21317.1 - 0.061 12.4 0.0 0.091 11.8 0.0 1.2 1 0 0 1 1 1 0 Cholesterol oxidase, substrate-binding LSM PF01423.17 EWM21320.1 - 1.2e-14 53.6 0.1 1.6e-14 53.1 0.1 1.2 1 0 0 1 1 1 1 LSM domain PCI PF01399.22 EWM21321.1 - 3e-10 40.3 0.0 6.7e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 PCI domain Kin17_mid PF10357.4 EWM21322.1 - 8.1e-44 148.3 1.4 8.1e-44 148.3 1.0 1.9 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein TFIID_90kDa PF04494.10 EWM21322.1 - 0.0062 16.6 0.1 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit zf-met PF12874.2 EWM21322.1 - 0.018 15.2 4.4 0.018 15.2 3.0 2.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Spore_III_AF PF09581.5 EWM21322.1 - 0.044 13.6 3.0 0.075 12.8 2.1 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) zf-C2H2_jaz PF12171.3 EWM21322.1 - 0.25 11.5 6.9 0.11 12.6 2.8 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DEAD PF00270.24 EWM21323.1 - 4.7e-43 146.6 0.4 1e-42 145.4 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EWM21323.1 - 2.5e-28 97.7 0.1 6.5e-28 96.4 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EWM21323.1 - 0.00017 21.2 0.0 0.00045 19.9 0.0 1.7 1 1 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 EWM21323.1 - 0.00024 20.9 0.0 0.00094 19.0 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 EWM21323.1 - 0.0045 16.3 0.0 0.0088 15.3 0.0 1.5 1 0 0 1 1 1 1 SecA DEAD-like domain AAA_22 PF13401.1 EWM21323.1 - 0.0064 16.6 0.0 0.017 15.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF1253 PF06862.7 EWM21323.1 - 0.016 13.6 0.0 0.077 11.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) AAA_30 PF13604.1 EWM21323.1 - 0.02 14.4 0.0 0.046 13.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EWM21323.1 - 0.028 13.3 0.0 0.047 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CMS1 PF14617.1 EWM21323.1 - 0.057 12.4 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Sulfotransfer_1 PF00685.22 EWM21324.1 - 7.2e-37 127.0 0.0 1.8e-27 96.2 0.0 2.4 2 1 0 2 2 2 2 Sulfotransferase domain Sulfotransfer_3 PF13469.1 EWM21324.1 - 7.4e-06 26.9 0.0 1.9e-05 25.6 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family DUF2637 PF10935.3 EWM21324.1 - 0.14 12.1 0.2 0.34 10.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2637) DP PF08781.5 EWM21325.1 - 5.5e-25 87.7 5.1 6.8e-17 61.4 0.1 2.4 2 0 0 2 2 2 2 Transcription factor DP E2F_TDP PF02319.15 EWM21325.1 - 1.5e-24 85.3 0.2 3.3e-24 84.2 0.1 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain R_equi_Vir PF05526.6 EWM21325.1 - 8.5 5.9 10.1 53 3.3 0.0 2.3 2 0 0 2 2 2 0 Rhodococcus equi virulence-associated protein GFO_IDH_MocA PF01408.17 EWM21326.1 - 3.4e-20 72.7 0.0 6.3e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EWM21326.1 - 3.1e-08 33.4 0.0 5.8e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Shikimate_DH PF01488.15 EWM21326.1 - 0.0032 17.5 0.0 0.0054 16.8 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.15 EWM21326.1 - 0.028 14.3 0.0 0.049 13.5 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ThiF PF00899.16 EWM21326.1 - 0.031 14.1 0.0 0.084 12.6 0.0 1.6 1 0 0 1 1 1 0 ThiF family CoA_binding PF02629.14 EWM21326.1 - 0.061 13.8 0.0 0.17 12.3 0.0 1.7 2 0 0 2 2 2 0 CoA binding domain Pkinase PF00069.20 EWM21327.1 - 4.3e-58 196.5 0.0 3.7e-57 193.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM21327.1 - 1.3e-33 116.1 0.0 2.4e-33 115.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EWM21327.1 - 0.00061 18.8 0.0 5.7 5.7 0.0 3.1 3 0 0 3 3 3 3 Kinase-like zf-B_box PF00643.19 EWM21327.1 - 0.0029 17.4 6.8 0.0053 16.6 4.7 1.3 1 0 0 1 1 1 1 B-box zinc finger Kdo PF06293.9 EWM21327.1 - 0.015 14.4 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IBR PF01485.16 EWM21327.1 - 1.9 8.3 7.0 2 8.3 3.9 1.7 2 0 0 2 2 2 0 IBR domain AAA_5 PF07728.9 EWM21329.1 - 1.1e-25 89.9 0.0 1.8e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) WD40 PF00400.27 EWM21329.1 - 3.3e-08 33.1 0.1 0.00046 19.9 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat AAA_5 PF07728.9 EWM21330.1 - 1.6e-23 82.9 0.0 2.6e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EWM21330.1 - 0.00014 21.9 0.3 0.0011 18.9 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 EWM21330.1 - 0.00053 19.9 0.0 0.00084 19.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EWM21330.1 - 0.0011 19.1 0.0 0.023 14.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EWM21330.1 - 0.0033 16.6 0.1 0.018 14.2 0.0 1.9 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF258 PF03193.11 EWM21330.1 - 0.009 15.2 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 EWM21330.1 - 0.012 15.5 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EWM21330.1 - 0.049 12.7 0.0 0.14 11.2 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin IstB_IS21 PF01695.12 EWM21330.1 - 0.083 12.3 0.2 0.16 11.4 0.1 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_29 PF13555.1 EWM21330.1 - 0.093 12.2 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_3 PF07726.6 EWM21330.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-CXXC PF02008.15 EWM21331.1 - 0.021 14.6 1.1 0.033 13.9 0.8 1.3 1 0 0 1 1 1 0 CXXC zinc finger domain Glyco_hydro_1 PF00232.13 EWM21332.1 - 2.1e-173 576.6 1.0 2.5e-173 576.4 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 DUF1180 PF06679.7 EWM21333.1 - 0.0054 16.6 0.3 0.0072 16.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) HEAT PF02985.17 EWM21335.1 - 6.7e-25 84.8 15.4 0.00017 21.4 0.1 7.7 7 0 0 7 7 7 6 HEAT repeat HEAT_2 PF13646.1 EWM21335.1 - 9e-16 57.9 12.7 3.2e-08 33.7 1.8 4.7 1 1 3 4 4 4 4 HEAT repeats HEAT_EZ PF13513.1 EWM21335.1 - 2.9e-08 33.9 15.0 0.00023 21.5 1.8 5.4 6 1 0 6 6 6 2 HEAT-like repeat CLASP_N PF12348.3 EWM21335.1 - 5.5e-05 22.6 0.0 0.11 11.8 0.0 3.2 1 1 0 2 2 2 2 CLASP N terminal Cnd1 PF12717.2 EWM21335.1 - 0.0024 17.7 0.1 3.1 7.6 0.0 2.9 1 1 2 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 EWM21335.1 - 0.0026 17.5 1.4 2.2 8.2 0.0 3.6 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat DNA_alkylation PF08713.6 EWM21335.1 - 0.017 14.6 0.1 1.4 8.3 0.0 3.2 2 2 1 3 3 3 0 DNA alkylation repair enzyme Vac14_Fab1_bd PF12755.2 EWM21335.1 - 0.017 15.4 0.0 2.9 8.3 0.0 3.2 1 1 2 3 3 3 0 Vacuolar 14 Fab1-binding region Cnd3 PF12719.2 EWM21335.1 - 0.022 13.7 0.1 0.04 12.8 0.1 1.4 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain Adaptin_N PF01602.15 EWM21335.1 - 0.082 11.2 0.3 0.19 10.0 0.2 1.6 1 1 0 1 1 1 0 Adaptin N terminal region JAB PF01398.16 EWM21337.1 - 0.034 13.9 0.0 0.065 12.9 0.0 1.5 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF1214 PF06742.6 EWM21339.1 - 0.00021 21.7 0.0 0.00062 20.1 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1214) HNH PF01844.18 EWM21340.1 - 2.5e-12 46.4 0.8 6.3e-12 45.1 0.5 1.7 2 0 0 2 2 2 1 HNH endonuclease HNH_4 PF13395.1 EWM21340.1 - 2.2e-08 33.6 0.0 5.5e-08 32.3 0.0 1.7 2 0 0 2 2 2 1 HNH endonuclease HNH_5 PF14279.1 EWM21340.1 - 4.5e-05 23.3 0.1 7.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 HNH endonuclease TT_ORF2 PF02957.10 EWM21340.1 - 0.055 14.1 6.2 3.4 8.3 0.1 3.2 3 0 0 3 3 3 0 TT viral ORF2 FbpA PF05833.6 EWM21341.1 - 5.9e-64 216.2 0.0 1.1e-52 179.1 0.0 2.2 2 0 0 2 2 2 2 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 EWM21341.1 - 5.7e-23 80.6 0.1 2.4e-22 78.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF814) Lactamase_B PF00753.22 EWM21343.1 - 1.1e-22 80.6 0.7 1.6e-22 80.1 0.5 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EWM21343.1 - 0.0035 16.9 0.0 0.0057 16.2 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DoxX PF07681.7 EWM21343.1 - 0.0064 16.8 0.3 0.027 14.9 0.1 2.0 2 0 0 2 2 2 1 DoxX Bromodomain PF00439.20 EWM21344.1 - 1e-10 41.3 0.0 2.4e-10 40.2 0.0 1.6 1 1 0 1 1 1 1 Bromodomain PHD PF00628.24 EWM21344.1 - 2.1e-06 27.3 0.8 2.1e-06 27.3 0.5 3.3 3 0 0 3 3 3 1 PHD-finger DUF4442 PF14539.1 EWM21345.1 - 1.8e-36 125.0 0.2 2.1e-36 124.8 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) SAM_1 PF00536.25 EWM21345.1 - 0.029 14.5 0.0 0.077 13.1 0.0 1.7 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) adh_short PF00106.20 EWM21346.1 - 0.002 18.0 0.1 0.032 14.1 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EWM21346.1 - 0.074 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 KR domain Kelch_2 PF07646.10 EWM21346.1 - 0.094 12.5 0.3 3.1 7.7 0.1 2.5 2 0 0 2 2 2 0 Kelch motif Ank_2 PF12796.2 EWM21347.1 - 2.2e-30 104.8 0.0 2.1e-17 63.2 0.0 4.0 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 EWM21347.1 - 5.4e-27 92.2 11.5 5.1e-07 29.1 0.1 7.8 8 1 0 8 8 8 4 Ankyrin repeat Ank_4 PF13637.1 EWM21347.1 - 4.7e-20 71.5 0.4 2.5e-09 37.3 0.0 4.9 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EWM21347.1 - 1.3e-17 63.3 4.6 3.8e-05 23.7 0.0 5.0 3 1 4 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM21347.1 - 3.1e-17 60.9 0.6 2.2e-05 24.2 0.0 6.4 7 0 0 7 7 7 4 Ankyrin repeat UAA PF08449.6 EWM21348.1 - 1.1e-86 290.4 13.9 1.4e-86 290.1 9.6 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EWM21348.1 - 8.6e-12 45.2 18.3 1.3e-05 25.2 4.0 2.5 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 EWM21348.1 - 2.2e-07 30.6 19.0 1.9e-05 24.3 7.0 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 EWM21348.1 - 3.7e-07 29.5 4.7 0.00019 20.6 0.3 2.5 3 0 0 3 3 3 2 Nucleotide-sugar transporter EmrE PF13536.1 EWM21348.1 - 9e-07 29.0 16.5 0.0015 18.6 3.7 2.9 2 1 0 2 2 2 2 Multidrug resistance efflux transporter Tim54 PF11711.3 EWM21348.1 - 0.15 10.6 0.0 0.22 10.0 0.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 UPF0546 PF10639.4 EWM21348.1 - 0.22 11.3 4.0 0.57 10.0 1.2 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 SAP PF02037.22 EWM21349.1 - 2.5e-11 42.7 1.8 2.5e-11 42.7 1.2 2.1 2 0 0 2 2 2 1 SAP domain PALP PF00291.20 EWM21350.1 - 0.066 12.4 0.0 0.099 11.8 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme RNase_PH PF01138.16 EWM21351.1 - 3.7e-19 69.3 0.0 1.1e-18 67.7 0.0 1.9 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EWM21351.1 - 2.4e-08 33.7 1.5 4.4e-08 32.9 0.0 2.1 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Proteasome PF00227.21 EWM21352.1 - 6e-28 97.4 0.2 1.8e-27 95.8 0.1 1.8 1 1 0 1 1 1 1 Proteasome subunit P5CR_dimer PF14748.1 EWM21352.1 - 0.012 15.5 1.0 0.028 14.4 0.7 1.5 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation ABG_transport PF03806.8 EWM21352.1 - 0.16 9.9 0.0 0.24 9.3 0.0 1.2 1 0 0 1 1 1 0 AbgT putative transporter family Cript PF10235.4 EWM21354.1 - 3.8e-18 65.6 3.1 3.8e-18 65.6 2.1 1.6 2 1 0 2 2 2 1 Microtubule-associated protein CRIPT DUF2039 PF10217.4 EWM21354.1 - 0.02 14.8 5.1 0.02 14.8 3.5 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) XPA_N PF01286.13 EWM21354.1 - 0.16 11.6 4.5 5.9 6.6 0.0 3.2 3 0 0 3 3 3 0 XPA protein N-terminal Endonuclease_7 PF02945.10 EWM21354.1 - 0.85 9.3 10.4 2.7 7.7 4.1 2.5 2 1 0 2 2 2 0 Recombination endonuclease VII C1_2 PF03107.11 EWM21354.1 - 3.3 7.8 14.9 8.7 6.5 0.7 3.2 3 0 0 3 3 3 0 C1 domain Sar8_2 PF03058.9 EWM21354.1 - 6.6 7.1 8.6 0.3 11.4 2.1 1.7 2 0 0 2 2 2 0 Sar8.2 family ubiquitin PF00240.18 EWM21355.1 - 1e-05 24.7 0.0 1.8e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EWM21355.1 - 0.0056 16.3 0.0 0.018 14.7 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like LRR_1 PF00560.28 EWM21356.1 - 2.6e-06 26.6 12.6 12 6.3 0.1 7.8 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_4 PF12799.2 EWM21356.1 - 0.00016 21.1 8.3 0.45 10.1 0.2 5.2 4 2 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EWM21356.1 - 0.0038 17.1 11.8 64 4.0 0.0 7.4 9 0 0 9 9 9 0 Leucine Rich repeat LRR_8 PF13855.1 EWM21356.1 - 0.11 12.2 8.5 9.5 6.0 1.4 5.0 5 2 0 5 5 5 0 Leucine rich repeat LRR_7 PF13504.1 EWM21356.1 - 0.19 12.0 20.1 6.5 7.4 0.2 8.0 8 0 0 8 8 8 0 Leucine rich repeat MutS_V PF00488.16 EWM21358.1 - 1.4e-79 266.7 0.0 2.8e-79 265.8 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EWM21358.1 - 4.1e-12 46.3 2.8 9.7e-12 45.0 1.9 1.6 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 EWM21358.1 - 6.5e-08 32.6 0.1 1.1e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.15 EWM21358.1 - 0.0043 17.0 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 MutS domain I Ank_2 PF12796.2 EWM21359.1 - 1.8e-55 185.2 0.0 6.8e-17 61.5 0.0 3.4 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 EWM21359.1 - 6.9e-35 117.1 2.2 1.6e-07 30.7 0.1 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 EWM21359.1 - 4.6e-30 102.9 3.8 8.9e-11 41.6 0.0 5.2 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM21359.1 - 6e-29 97.2 0.2 1e-05 25.2 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 EWM21359.1 - 1e-27 95.9 2.4 2.1e-10 40.8 0.1 4.8 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Complex1_LYR PF05347.10 EWM21366.1 - 2e-15 56.3 0.9 2e-15 56.3 0.6 1.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EWM21366.1 - 2.3e-10 40.5 4.0 4e-10 39.7 2.8 1.6 1 1 0 1 1 1 1 Complex1_LYR-like CNH PF00780.17 EWM21366.1 - 0.023 14.1 0.4 0.028 13.8 0.3 1.1 1 0 0 1 1 1 0 CNH domain Neuregulin PF02158.10 EWM21366.1 - 0.059 12.1 1.8 0.071 11.8 1.2 1.1 1 0 0 1 1 1 0 Neuregulin family Complex1_LYR_2 PF13233.1 EWM21366.1 - 0.77 10.2 5.1 2.5 8.6 3.5 1.8 1 1 0 1 1 1 0 Complex1_LYR-like CENP-T PF15511.1 EWM21370.1 - 0.41 9.8 11.2 0.012 14.8 2.4 2.0 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T Nop14 PF04147.7 EWM21370.1 - 3.4 5.4 4.8 5.3 4.8 3.3 1.3 1 0 0 1 1 1 0 Nop14-like family PfkB PF00294.19 EWM21371.1 - 2.1e-10 40.2 0.0 5.8e-09 35.4 0.0 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Glyco_transf_34 PF05637.7 EWM21373.1 - 0.03 13.8 0.0 2.8 7.3 0.0 2.1 2 0 0 2 2 2 0 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 EWM21373.1 - 0.097 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF273 DHQ_synthase PF01761.15 EWM21378.1 - 1.4e-103 345.3 0.0 1.7e-103 345.0 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.1 EWM21378.1 - 7.9e-13 48.2 0.2 2.9e-12 46.4 0.2 1.8 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.14 EWM21378.1 - 1.6e-07 30.3 2.0 1.1e-06 27.5 1.4 2.0 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase WD40 PF00400.27 EWM21379.1 - 6.6e-19 67.0 12.9 5.8e-06 25.9 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Ribosomal_TL5_C PF14693.1 EWM21379.1 - 0.056 13.6 0.1 0.096 12.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein TL5, C-terminal domain ABC_tran PF00005.22 EWM21381.1 - 1.2e-34 119.5 0.0 8.6e-34 116.7 0.0 2.2 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 EWM21381.1 - 2.5e-26 92.7 1.7 3.2e-26 92.3 1.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EWM21381.1 - 2.5e-07 30.1 0.1 2.2e-05 23.7 0.0 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EWM21381.1 - 1e-06 28.9 0.1 4.2e-06 26.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 EWM21381.1 - 0.00023 21.2 0.0 0.0014 18.6 0.0 2.1 1 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EWM21381.1 - 0.00028 21.7 0.5 0.00092 20.0 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EWM21381.1 - 0.00042 19.8 0.0 0.083 12.3 0.0 2.6 2 0 0 2 2 2 1 AAA-like domain DUF258 PF03193.11 EWM21381.1 - 0.0011 18.1 0.0 0.0032 16.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EWM21381.1 - 0.0032 17.5 0.1 0.017 15.2 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EWM21381.1 - 0.0042 16.5 0.0 0.026 14.0 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_ATPase PF09818.4 EWM21381.1 - 0.0075 14.9 0.0 0.083 11.4 0.0 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class NACHT PF05729.7 EWM21381.1 - 0.011 15.4 0.1 0.082 12.5 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.1 EWM21381.1 - 0.012 15.4 0.0 0.042 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EWM21381.1 - 0.019 14.6 0.0 0.06 13.0 0.0 1.9 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 EWM21381.1 - 0.026 13.6 0.0 0.075 12.1 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 EWM21381.1 - 0.034 14.0 0.0 0.11 12.3 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.1 EWM21381.1 - 0.036 14.0 0.3 0.44 10.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 EWM21381.1 - 0.051 13.8 0.0 0.14 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EWM21381.1 - 0.07 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATP-synt_ab PF00006.20 EWM21381.1 - 0.098 12.1 0.0 0.74 9.2 0.0 2.0 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.18 EWM21381.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 EWM21381.1 - 0.16 12.1 0.0 1.1 9.4 0.0 2.1 2 0 0 2 2 2 0 RNA helicase PfkB PF00294.19 EWM21385.1 - 8.4e-67 225.4 0.4 1e-66 225.1 0.3 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase LEA_4 PF02987.11 EWM21387.1 - 0.08 12.8 2.4 0.29 11.0 1.6 1.8 1 1 0 1 1 1 0 Late embryogenesis abundant protein LEA_4 PF02987.11 EWM21388.1 - 0.1 12.4 2.9 0.38 10.6 2.0 1.8 1 1 0 1 1 1 0 Late embryogenesis abundant protein Cyt-b5 PF00173.23 EWM21389.1 - 4.9e-15 55.0 0.0 1e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain F-box-like PF12937.2 EWM21389.1 - 7.6e-06 25.5 0.0 2.2e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EWM21389.1 - 0.00018 21.0 0.0 0.00038 20.0 0.0 1.5 1 0 0 1 1 1 1 F-box domain TraU PF06834.6 EWM21390.1 - 0.051 12.6 0.0 0.099 11.7 0.0 1.5 1 0 0 1 1 1 0 TraU protein CAF-1_p150 PF11600.3 EWM21390.1 - 3.1 7.1 17.4 0.14 11.5 3.3 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3446 PF11928.3 EWM21390.1 - 9.5 6.4 19.6 8.9 6.5 6.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Transaldolase PF00923.14 EWM21391.1 - 1.9e-14 53.4 0.0 2.5e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Transaldolase DUF1681 PF07933.9 EWM21392.1 - 3.3e-24 85.2 0.0 8.6e-24 83.9 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1681) IKI3 PF04762.7 EWM21395.1 - 2.9e-39 134.6 0.0 3.1e-39 134.5 0.0 1.0 1 0 0 1 1 1 1 IKI3 family PPR_2 PF13041.1 EWM21396.1 - 8.2e-93 304.2 0.0 5.4e-12 45.4 0.1 16.0 5 3 12 17 17 17 15 PPR repeat family PPR PF01535.15 EWM21396.1 - 4.8e-72 233.0 18.2 3.6e-07 29.7 0.0 18.3 18 0 0 18 18 18 13 PPR repeat PPR_3 PF13812.1 EWM21396.1 - 3.2e-62 201.6 24.0 3.5e-06 26.8 0.0 16.5 18 0 0 18 18 17 11 Pentatricopeptide repeat domain PPR_1 PF12854.2 EWM21396.1 - 1.2e-48 162.2 4.3 2e-07 30.3 0.0 15.0 16 0 0 16 16 16 7 PPR repeat Smr PF01713.16 EWM21396.1 - 4.9e-06 26.6 0.0 1.7e-05 24.9 0.0 1.9 1 0 0 1 1 1 1 Smr domain TPR_14 PF13428.1 EWM21396.1 - 9.2e-06 25.8 17.6 1.6 9.5 0.0 9.0 11 1 1 12 12 8 1 Tetratricopeptide repeat TPR_7 PF13176.1 EWM21396.1 - 0.0006 19.4 4.5 20 5.2 0.0 7.5 10 0 0 10 10 9 0 Tetratricopeptide repeat ECSIT PF06239.6 EWM21396.1 - 0.0011 17.9 0.0 9.8 4.9 0.0 5.2 5 1 1 6 6 6 1 Evolutionarily conserved signalling intermediate in Toll pathway TPR_12 PF13424.1 EWM21396.1 - 0.0018 18.1 5.1 32 4.5 0.0 6.5 5 3 3 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.23 EWM21396.1 - 0.022 14.3 0.6 16 5.2 0.2 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Clathrin PF00637.15 EWM21396.1 - 0.042 13.4 0.0 18 4.8 0.0 3.7 4 0 0 4 4 4 0 Region in Clathrin and VPS TPR_2 PF07719.12 EWM21396.1 - 0.17 11.8 9.2 7.7 6.7 0.4 5.2 7 0 0 7 7 5 0 Tetratricopeptide repeat RPM2 PF08579.6 EWM21396.1 - 0.47 10.5 0.0 10 6.2 0.0 2.9 2 1 1 3 3 3 0 Mitochondrial ribonuclease P subunit (RPM2) TPR_16 PF13432.1 EWM21396.1 - 2.5 8.8 17.1 0.91 10.2 0.7 6.3 5 3 2 7 7 6 0 Tetratricopeptide repeat APG6 PF04111.7 EWM21397.1 - 2.2e-14 53.2 1.1 2.3e-06 26.8 0.6 3.0 2 1 0 2 2 2 2 Autophagy protein Apg6 Troponin PF00992.15 EWM21397.1 - 9.8 6.2 10.5 18 5.3 7.3 1.3 1 0 0 1 1 1 0 Troponin APG6 PF04111.7 EWM21398.1 - 2.3e-14 53.1 1.2 2.3e-06 26.8 0.6 3.0 2 1 0 2 2 2 2 Autophagy protein Apg6 Troponin PF00992.15 EWM21398.1 - 9.8 6.2 10.5 18 5.3 7.3 1.3 1 0 0 1 1 1 0 Troponin ABC2_membrane PF01061.19 EWM21399.1 - 5.4e-34 117.1 17.8 8.6e-34 116.5 12.3 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EWM21399.1 - 8.7e-05 22.8 0.0 0.00013 22.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 EWM21399.1 - 0.73 8.8 29.5 11 4.8 20.5 2.1 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF809 PF05663.6 EWM21399.1 - 2.3 8.1 7.8 4.1 7.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF809) Proteasome PF00227.21 EWM21400.1 - 8.7e-56 188.2 0.0 1.4e-55 187.5 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EWM21400.1 - 6.5e-14 50.9 0.0 1.2e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ADH_zinc_N PF00107.21 EWM21400.1 - 0.00034 20.1 0.2 0.0018 17.8 0.1 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ThiF PF00899.16 EWM21400.1 - 0.11 12.2 0.3 0.41 10.4 0.2 1.9 2 0 0 2 2 2 0 ThiF family Cep57_MT_bd PF06657.8 EWM21401.1 - 0.51 10.3 4.7 0.35 10.8 1.3 2.2 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 APG6 PF04111.7 EWM21401.1 - 0.82 8.6 2.7 1.3 8.0 1.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 ABC2_membrane PF01061.19 EWM21402.1 - 2.3e-35 121.6 18.0 4.2e-35 120.8 12.5 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EWM21402.1 - 1.3e-15 57.8 0.0 2.2e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 EWM21402.1 - 4.3e-07 29.2 14.0 6.1e-07 28.7 9.7 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.1 EWM21402.1 - 2.7e-05 24.2 0.1 0.005 16.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EWM21402.1 - 9.2e-05 21.8 0.3 0.00064 19.2 0.1 2.5 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EWM21402.1 - 0.00028 20.3 0.1 0.00081 18.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EWM21402.1 - 0.00041 20.3 0.0 0.0008 19.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EWM21402.1 - 0.019 15.1 0.1 0.065 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EWM21402.1 - 0.023 14.6 0.6 0.044 13.7 0.4 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EWM21402.1 - 0.029 13.5 0.0 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_19 PF13245.1 EWM21402.1 - 0.057 13.1 0.2 0.45 10.2 0.3 2.3 2 0 0 2 2 2 0 Part of AAA domain PduV-EutP PF10662.4 EWM21402.1 - 0.06 12.8 0.2 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 EWM21402.1 - 0.065 14.0 2.1 0.15 12.9 0.1 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EWM21402.1 - 0.08 12.5 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.1 EWM21402.1 - 0.13 12.1 1.5 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 EWM21402.1 - 0.24 10.6 0.1 0.39 9.9 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_10 PF12846.2 EWM21402.1 - 0.36 10.2 1.1 0.43 9.9 0.1 1.6 2 0 0 2 2 2 0 AAA-like domain AAA_18 PF13238.1 EWM21402.1 - 0.42 10.9 0.1 0.42 10.9 0.1 1.7 2 0 0 2 2 1 0 AAA domain AAA_15 PF13175.1 EWM21402.1 - 0.5 9.3 0.0 1.4 7.8 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain FKBP_C PF00254.23 EWM21403.1 - 1.2e-22 79.7 0.0 2.4e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Saccharop_dh PF03435.13 EWM21404.1 - 5.6e-74 249.4 0.0 6.6e-74 249.2 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Saccharop_dh_N PF04455.7 EWM21404.1 - 2e-12 47.1 0.0 5.2e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 LOR/SDH bifunctional enzyme conserved region TrkA_N PF02254.13 EWM21404.1 - 0.016 15.1 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_10 PF13460.1 EWM21404.1 - 0.019 14.9 0.9 0.29 11.1 0.6 2.3 1 1 0 1 1 1 0 NADH(P)-binding DAGAT PF03982.8 EWM21405.1 - 1.2e-37 129.1 0.0 2e-37 128.4 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.16 EWM21405.1 - 0.16 11.4 0.0 0.32 10.4 0.0 1.5 1 0 0 1 1 1 0 Acyltransferase AlaDh_PNT_N PF05222.10 EWM21406.1 - 1.7e-22 79.8 0.0 3.6e-22 78.8 0.0 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EWM21406.1 - 7e-21 74.5 0.1 3e-19 69.2 0.0 2.3 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pkinase PF00069.20 EWM21408.1 - 0.00014 21.0 0.2 0.00024 20.3 0.1 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM21408.1 - 0.00078 18.5 0.1 0.0087 15.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EWM21409.1 - 4.9e-30 104.5 0.0 8.1e-30 103.8 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM21409.1 - 9.2e-25 87.1 0.0 2.4e-24 85.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EWM21409.1 - 2e-06 27.0 0.0 3.6e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EWM21409.1 - 0.00015 21.5 0.1 0.00026 20.8 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EWM21409.1 - 0.0033 16.5 0.0 0.0048 16.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PsbU PF06514.6 EWM21409.1 - 0.099 12.5 0.1 0.21 11.4 0.0 1.5 1 1 1 2 2 2 0 Photosystem II 12 kDa extrinsic protein (PsbU) ECH PF00378.15 EWM21411.1 - 2.1e-57 194.0 0.1 3.2e-57 193.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family 3HCDH_N PF02737.13 EWM21411.1 - 4.3e-56 189.4 0.3 7.6e-56 188.5 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EWM21411.1 - 0.0007 19.3 0.0 0.0015 18.2 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DAO PF01266.19 EWM21411.1 - 0.002 17.0 0.0 0.0031 16.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_2 PF03446.10 EWM21411.1 - 0.0041 16.9 2.3 0.036 13.8 0.1 2.6 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_8 PF13450.1 EWM21411.1 - 0.025 14.6 0.2 0.074 13.0 0.2 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 3HCDH PF00725.17 EWM21411.1 - 0.035 14.5 0.3 0.62 10.5 0.0 2.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DUF3628 PF12300.3 EWM21411.1 - 0.11 12.5 0.3 0.22 11.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3628) Radical_SAM PF04055.16 EWM21412.1 - 2.3e-11 44.1 0.0 4.3e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily zf-C3HC4_2 PF13923.1 EWM21413.1 - 1.7e-09 37.5 13.3 2.8e-09 36.8 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EWM21413.1 - 1.7e-07 30.7 11.7 2.7e-07 30.1 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EWM21413.1 - 5.9e-06 25.8 12.6 8.8e-06 25.2 8.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EWM21413.1 - 5.3e-05 22.9 13.4 8.9e-05 22.2 9.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EWM21413.1 - 0.00036 20.2 11.3 0.00067 19.3 7.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EWM21413.1 - 0.0049 16.7 11.4 0.0098 15.7 7.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EWM21413.1 - 0.013 15.3 5.9 0.02 14.7 4.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EWM21413.1 - 0.44 10.6 8.0 0.83 9.8 5.6 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger DUF4656 PF15551.1 EWM21413.1 - 0.68 9.0 7.5 0.79 8.8 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4656) DUF4187 PF13821.1 EWM21413.1 - 3.7 7.2 10.3 0.25 10.9 3.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) zf-RING_4 PF14570.1 EWM21413.1 - 7.4 6.2 11.1 18 5.0 7.7 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Gtr1_RagA PF04670.7 EWM21414.1 - 3.5e-57 193.2 0.1 3.8e-38 130.9 0.2 2.1 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EWM21414.1 - 8.5e-05 23.0 0.0 0.047 14.1 0.0 3.0 2 1 1 3 3 3 1 Miro-like protein SRPRB PF09439.5 EWM21414.1 - 0.0014 17.8 0.0 0.0029 16.8 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 EWM21414.1 - 0.0019 18.0 0.0 0.0039 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EWM21414.1 - 0.0024 17.9 0.0 0.054 13.4 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain Arch_ATPase PF01637.13 EWM21414.1 - 0.0042 16.8 0.0 0.0076 15.9 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase Arf PF00025.16 EWM21414.1 - 0.032 13.4 0.0 5.4 6.2 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA PF00004.24 EWM21414.1 - 0.11 12.6 0.0 0.85 9.8 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Gtr1_RagA PF04670.7 EWM21415.1 - 1.2e-57 194.7 0.1 1.9e-38 131.8 0.2 2.0 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EWM21415.1 - 3.5e-05 24.2 0.0 0.031 14.7 0.0 2.9 2 1 1 3 3 3 1 Miro-like protein AAA_16 PF13191.1 EWM21415.1 - 0.00094 19.2 0.0 0.036 14.0 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain SRPRB PF09439.5 EWM21415.1 - 0.00095 18.4 0.0 0.0019 17.4 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 EWM21415.1 - 0.0012 18.7 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EWM21415.1 - 0.0027 17.4 0.0 0.005 16.5 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase Arf PF00025.16 EWM21415.1 - 0.013 14.7 0.0 3.5 6.8 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA PF00004.24 EWM21415.1 - 0.055 13.6 0.0 0.57 10.3 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Gtr1_RagA PF04670.7 EWM21416.1 - 1.2e-57 194.7 0.1 1.9e-38 131.9 0.2 2.0 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EWM21416.1 - 3.3e-05 24.3 0.0 0.03 14.8 0.0 2.9 2 1 1 3 3 3 1 Miro-like protein SRPRB PF09439.5 EWM21416.1 - 0.00093 18.4 0.0 0.0018 17.5 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 EWM21416.1 - 0.0012 18.7 0.0 0.0025 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EWM21416.1 - 0.0014 18.6 0.0 0.058 13.3 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain Arch_ATPase PF01637.13 EWM21416.1 - 0.0041 16.8 0.0 0.0074 16.0 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase Arf PF00025.16 EWM21416.1 - 0.017 14.3 0.0 4.9 6.3 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA PF00004.24 EWM21416.1 - 0.054 13.7 0.0 0.56 10.4 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) HLH PF00010.21 EWM21417.1 - 0.02 14.5 0.4 0.039 13.6 0.3 1.5 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain REV PF00424.13 EWM21417.1 - 2.8 7.9 9.6 4.8 7.1 6.7 1.5 1 1 0 1 1 1 0 REV protein (anti-repression trans-activator protein) zf-DHHC PF01529.15 EWM21418.1 - 6.9e-22 77.6 6.8 6.4e-21 74.5 4.7 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase NPL4 PF05021.10 EWM21419.1 - 8.8e-39 133.4 0.0 4.4e-38 131.1 0.0 2.1 1 1 0 1 1 1 1 NPL4 family UN_NPL4 PF11543.3 EWM21419.1 - 1.7e-07 31.3 0.0 3.2e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 ubiquitin PF00240.18 EWM21419.1 - 9.5e-05 21.7 0.0 0.0002 20.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EWM21419.1 - 0.013 15.1 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Kazal_1 PF00050.16 EWM21419.1 - 0.057 13.4 0.1 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain Pyridoxal_deC PF00282.14 EWM21420.1 - 3e-19 68.7 0.0 4e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EWM21420.1 - 3.7e-08 32.4 0.1 1.7e-07 30.3 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EWM21420.1 - 1.6e-07 30.6 0.8 2.5e-07 30.0 0.5 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family MoCF_biosynth PF00994.19 EWM21421.1 - 7.4e-32 109.7 0.1 1.4e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain PAPS_reduct PF01507.14 EWM21421.1 - 3.8e-24 85.4 0.0 8.9e-17 61.4 0.0 2.5 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family DUF1737 PF08410.5 EWM21421.1 - 0.017 14.8 0.0 0.053 13.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1737) Sec10 PF07393.6 EWM21421.1 - 0.41 8.7 0.1 0.56 8.3 0.1 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 Glyco_transf_20 PF00982.16 EWM21423.1 - 3.6e-129 431.3 0.0 5.4e-129 430.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EWM21423.1 - 1.6e-47 161.3 0.0 3.5e-47 160.2 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase CBM_20 PF00686.14 EWM21423.1 - 4e-13 48.7 1.0 9.6e-12 44.3 0.0 2.7 3 0 0 3 3 3 1 Starch binding domain Glycos_transf_1 PF00534.15 EWM21423.1 - 0.00077 18.9 0.2 1.4 8.3 0.1 3.2 2 1 0 2 2 2 2 Glycosyl transferases group 1 Hydrolase_3 PF08282.7 EWM21423.1 - 0.093 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Abhydrolase_6 PF12697.2 EWM21424.1 - 1.2e-14 54.7 0.1 1.8e-14 54.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EWM21424.1 - 3.3e-14 52.4 0.0 6.9e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 EWM21424.1 - 3.4e-12 46.3 0.0 1.2e-11 44.5 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EWM21424.1 - 9.9e-05 21.9 0.0 0.00022 20.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EWM21424.1 - 0.0037 16.8 0.0 0.011 15.3 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 EWM21424.1 - 0.0099 15.3 0.0 0.42 9.9 0.0 2.2 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_4 PF08386.5 EWM21424.1 - 0.15 12.0 0.0 1.9 8.3 0.0 2.5 3 0 0 3 3 3 0 TAP-like protein DUF2424 PF10340.4 EWM21424.1 - 0.16 10.5 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 EWM21425.1 - 1.2e-14 54.7 0.1 1.8e-14 54.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EWM21425.1 - 3.3e-14 52.4 0.0 6.9e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 EWM21425.1 - 3.4e-12 46.3 0.0 1.2e-11 44.5 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EWM21425.1 - 9.9e-05 21.9 0.0 0.00022 20.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EWM21425.1 - 0.0037 16.8 0.0 0.011 15.3 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 EWM21425.1 - 0.0099 15.3 0.0 0.42 9.9 0.0 2.2 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_4 PF08386.5 EWM21425.1 - 0.15 12.0 0.0 1.9 8.3 0.0 2.5 3 0 0 3 3 3 0 TAP-like protein DUF2424 PF10340.4 EWM21425.1 - 0.16 10.5 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) RNA_pol_L_2 PF13656.1 EWM21426.1 - 3.9e-23 80.6 0.0 4.7e-23 80.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EWM21426.1 - 2.2e-07 29.9 0.0 3e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Shugoshin_N PF07558.6 EWM21426.1 - 0.023 14.3 0.0 0.054 13.2 0.0 1.6 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region SbcD_C PF12320.3 EWM21426.1 - 0.034 14.1 0.2 0.045 13.7 0.2 1.2 1 0 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain RNA_pol_L_2 PF13656.1 EWM21427.1 - 1.6e-19 69.1 0.0 1.9e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EWM21427.1 - 8.7e-05 21.5 0.0 0.00012 21.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF2839 PF10999.3 EWM21428.1 - 0.031 14.2 0.4 0.27 11.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) Pyr_redox_2 PF07992.9 EWM21431.1 - 2.4e-27 96.1 0.0 9.3e-27 94.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thioredoxin PF00085.15 EWM21431.1 - 1.1e-14 53.9 0.0 2.3e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Pyr_redox PF00070.22 EWM21431.1 - 5.8e-11 42.6 0.0 1.5e-08 34.8 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EWM21431.1 - 1e-08 35.5 0.1 0.00011 22.3 0.0 3.3 1 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EWM21431.1 - 1.6e-06 27.3 0.4 3.8e-06 26.1 0.1 1.7 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 EWM21431.1 - 3.4e-06 26.1 3.1 8.9e-06 24.7 0.2 2.6 2 1 1 3 3 3 1 FAD binding domain DAO PF01266.19 EWM21431.1 - 4.1e-06 25.9 2.7 0.025 13.4 0.1 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EWM21431.1 - 5.6e-05 23.0 0.0 5.6e-05 23.0 0.0 3.0 4 0 0 4 4 3 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EWM21431.1 - 0.0001 21.2 1.8 0.013 14.3 0.1 3.4 3 0 0 3 3 3 1 Glucose inhibited division protein A Thioredoxin_7 PF13899.1 EWM21431.1 - 0.00011 22.1 0.0 0.00029 20.7 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like HI0933_like PF03486.9 EWM21431.1 - 0.00021 19.9 0.6 0.0033 15.9 0.1 2.5 3 0 0 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.2 EWM21431.1 - 0.00021 20.5 0.2 0.00021 20.5 0.1 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thioredoxin_2 PF13098.1 EWM21431.1 - 0.0011 19.2 0.0 0.0043 17.2 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Glutaredoxin PF00462.19 EWM21431.1 - 0.0027 17.6 0.0 0.0081 16.1 0.0 1.9 1 0 0 1 1 1 1 Glutaredoxin K_oxygenase PF13434.1 EWM21431.1 - 0.0033 16.4 0.0 0.073 11.9 0.0 2.4 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EWM21431.1 - 0.021 14.5 1.1 1.5 8.5 0.0 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EWM21431.1 - 0.026 13.1 0.2 0.078 11.5 0.1 1.8 3 0 0 3 3 3 0 Tryptophan halogenase Thioredoxin_4 PF13462.1 EWM21431.1 - 0.033 14.2 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin TraF PF13728.1 EWM21431.1 - 0.099 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_3 PF13192.1 EWM21431.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain NAD_binding_7 PF13241.1 EWM21431.1 - 0.15 12.2 0.1 12 6.2 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding Polyketide_cyc PF03364.15 EWM21432.1 - 3.9e-12 46.3 0.2 8.2e-12 45.2 0.1 1.5 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 EWM21432.1 - 5.3e-11 42.8 0.2 7.3e-11 42.4 0.1 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Flavi_M PF01004.14 EWM21432.1 - 0.082 12.3 0.3 0.34 10.3 0.3 1.9 2 0 0 2 2 2 0 Flavivirus envelope glycoprotein M BROMI PF14961.1 EWM21433.1 - 7.7e-09 33.3 0.0 0.00014 19.1 0.0 2.2 2 0 0 2 2 2 2 Broad-minded protein Creb_binding PF09030.5 EWM21433.1 - 0.1 12.7 0.8 0.43 10.7 0.2 2.3 2 0 0 2 2 2 0 Creb binding HVSL PF09749.4 EWM21434.1 - 2.1e-14 53.1 0.3 1.6e-12 46.9 0.1 2.7 1 1 1 2 2 2 1 Uncharacterised conserved protein BUD22 PF09073.5 EWM21434.1 - 0.055 12.5 1.5 0.097 11.7 1.1 1.3 1 0 0 1 1 1 0 BUD22 DUF4637 PF15470.1 EWM21434.1 - 2.4 7.7 12.7 0.45 10.1 4.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4637) WD40 PF00400.27 EWM21435.1 - 1.2e-45 151.8 6.5 2.5e-09 36.6 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EWM21435.1 - 1.5e-27 95.2 0.1 3e-27 94.2 0.1 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Mitofilin PF09731.4 EWM21436.1 - 5.5e-44 150.8 24.3 1.5e-43 149.3 16.8 1.5 1 1 0 1 1 1 1 Mitochondrial inner membrane protein TPR_14 PF13428.1 EWM21436.1 - 0.55 11.0 11.2 4.7 8.1 1.2 4.4 3 2 0 3 3 3 0 Tetratricopeptide repeat Gluconate_2-dh3 PF13618.1 EWM21436.1 - 1.6 8.9 7.6 5.5 7.1 4.8 2.4 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 XPA_N PF01286.13 EWM21437.1 - 0.24 11.1 9.4 0.83 9.3 1.9 2.4 2 0 0 2 2 2 0 XPA protein N-terminal Stc1 PF12898.2 EWM21437.1 - 4.1 7.5 11.8 17 5.5 8.2 2.0 1 1 0 1 1 1 0 Stc1 domain Merozoite_SPAM PF07133.6 EWM21438.1 - 0.012 15.4 25.9 0.012 15.4 17.9 2.2 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) Spore_coat_CotO PF14153.1 EWM21438.1 - 0.63 9.4 20.1 3.3 7.1 12.5 2.3 2 0 0 2 2 2 0 Spore coat protein CotO DHHW PF14286.1 EWM21438.1 - 0.94 8.7 6.9 1.3 8.2 4.8 1.2 1 0 0 1 1 1 0 DHHW protein Zip PF02535.17 EWM21438.1 - 1.4 7.8 5.1 2.4 7.0 3.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter AIF_C PF14721.1 EWM21438.1 - 2.1 8.5 4.9 5.9 7.1 3.4 1.8 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Nop14 PF04147.7 EWM21438.1 - 2.2 6.0 40.6 0.015 13.2 19.3 2.1 2 0 0 2 2 2 0 Nop14-like family Autophagy_act_C PF03987.10 EWM21439.1 - 0.00016 21.7 0.0 0.0003 20.9 0.0 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain NUDIX PF00293.23 EWM21440.1 - 6e-15 55.0 0.0 8.3e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.23 EWM21441.1 - 6e-15 55.0 0.0 8.3e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Voltage_CLC PF00654.15 EWM21442.1 - 7e-88 295.0 20.6 7e-88 295.0 14.3 2.0 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EWM21442.1 - 3.5e-12 45.9 0.3 8.1e-05 22.3 0.0 2.7 2 0 0 2 2 2 2 CBS domain TAT_signal PF10518.4 EWM21442.1 - 0.0016 18.2 1.1 0.0016 18.2 0.8 4.5 5 0 0 5 5 5 1 TAT (twin-arginine translocation) pathway signal sequence Aminotran_1_2 PF00155.16 EWM21443.1 - 1.4e-50 172.2 0.0 1.9e-50 171.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EWM21443.1 - 0.0011 17.3 0.0 0.0017 16.6 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EWM21443.1 - 0.0071 15.4 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EWM21443.1 - 0.012 14.3 0.0 0.018 13.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V FAM217 PF15344.1 EWM21444.1 - 0.07 12.6 3.9 0.093 12.2 2.7 1.2 1 0 0 1 1 1 0 FAM217 family PSK PF06404.7 EWM21444.1 - 0.1 13.3 2.3 0.24 12.2 1.6 1.6 1 0 0 1 1 1 0 Phytosulfokine precursor protein (PSK) DUF3578 PF12102.3 EWM21444.1 - 0.13 11.7 0.3 10 5.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3578) Tombus_movement PF05318.7 EWM21444.1 - 3.3 8.4 6.2 2.5 8.7 2.8 2.1 1 1 0 1 1 1 0 Tombusvirus movement protein zf-SNAP50_C PF12251.3 EWM21445.1 - 2.2e-31 108.8 0.1 4.6e-31 107.7 0.1 1.5 1 1 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal WD40 PF00400.27 EWM21446.1 - 1.4e-11 43.7 7.3 4e-05 23.3 0.0 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat Erf4 PF10256.4 EWM21448.1 - 4.6e-08 32.9 0.0 6e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family WD40 PF00400.27 EWM21449.1 - 1.1e-33 113.9 3.7 1.6e-10 40.4 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EWM21449.1 - 0.047 11.8 0.1 0.45 8.5 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 PQQ PF01011.16 EWM21449.1 - 0.066 12.7 0.0 1.4 8.5 0.0 2.9 3 0 0 3 3 3 0 PQQ enzyme repeat Nucleoporin_N PF08801.6 EWM21449.1 - 0.092 11.4 0.0 1.3 7.6 0.0 2.1 2 0 0 2 2 2 0 Nup133 N terminal like Acetyltransf_1 PF00583.19 EWM21450.1 - 6.7e-13 48.4 0.0 1e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EWM21450.1 - 7.5e-05 22.4 0.0 0.00022 20.8 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.1 EWM21450.1 - 0.00011 22.3 0.0 0.00019 21.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EWM21450.1 - 0.0031 17.6 0.0 0.0054 16.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain YL1 PF05764.8 EWM21452.1 - 0.68 9.4 6.5 0.83 9.2 4.5 1.2 1 0 0 1 1 1 0 YL1 nuclear protein PAT1 PF09770.4 EWM21452.1 - 0.91 7.6 3.2 1.1 7.4 2.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Nop14 PF04147.7 EWM21452.1 - 4.1 5.2 7.4 4.8 4.9 5.1 1.0 1 0 0 1 1 1 0 Nop14-like family OppC_N PF12911.2 EWM21453.1 - 0.096 12.0 0.1 0.096 12.0 0.1 3.2 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C DUF805 PF05656.9 EWM21453.1 - 0.16 11.7 13.2 0.1 12.4 3.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF805) Na_Ca_ex PF01699.19 EWM21453.1 - 0.21 11.1 8.9 3.4 7.2 6.2 2.1 1 1 0 1 1 1 0 Sodium/calcium exchanger protein TctB PF07331.6 EWM21453.1 - 0.91 9.1 10.9 1.3 8.6 7.6 1.3 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family MARVEL PF01284.18 EWM21453.1 - 1.4 8.6 17.3 6.9 6.4 11.1 2.5 1 1 0 1 1 1 0 Membrane-associating domain zf-LITAF-like PF10601.4 EWM21453.1 - 1.5 8.7 5.1 12 5.8 0.0 3.0 3 1 0 3 3 3 0 LITAF-like zinc ribbon domain DUF4064 PF13273.1 EWM21453.1 - 7.1 6.8 12.9 2.1 8.4 4.6 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF4064) DUF373 PF04123.8 EWM21453.1 - 7.3 5.4 9.2 20 4.0 6.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF373) DUF202 PF02656.10 EWM21453.1 - 9.9 6.4 15.8 7.4 6.8 1.3 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Ras PF00071.17 EWM21454.1 - 5.8e-58 194.8 0.0 6.9e-58 194.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EWM21454.1 - 6.8e-18 65.2 0.0 1.2e-17 64.4 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EWM21454.1 - 3.2e-12 46.0 0.0 4.3e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EWM21454.1 - 0.0011 18.9 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EWM21454.1 - 0.002 17.2 0.0 0.0023 17.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EWM21454.1 - 0.0074 15.7 0.0 0.073 12.4 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF2358 PF10184.4 EWM21456.1 - 1.6e-16 60.2 0.0 3.3e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SOUL PF04832.7 EWM21456.1 - 7.7e-15 54.8 0.3 1.2e-14 54.2 0.2 1.3 1 0 0 1 1 1 1 SOUL heme-binding protein SnoaL_2 PF12680.2 EWM21456.1 - 0.011 16.1 0.0 0.029 14.7 0.0 1.7 1 0 0 1 1 1 0 SnoaL-like domain FHA PF00498.21 EWM21457.1 - 9.6e-14 51.2 0.0 1.5e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 FHA domain PGBA_C PF15437.1 EWM21457.1 - 0.31 11.1 3.2 0.57 10.3 2.2 1.4 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal polyprenyl_synt PF00348.12 EWM21458.1 - 9.5e-70 234.4 0.0 1.2e-69 234.1 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase VLPT PF07122.6 EWM21458.1 - 0.0082 15.7 0.0 0.02 14.5 0.0 1.7 1 0 0 1 1 1 1 Variable length PCR target protein (VLPT) MCM PF00493.18 EWM21459.1 - 3.7e-131 436.8 0.0 5.7e-131 436.2 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EWM21459.1 - 2.6e-19 69.9 0.4 1.2e-18 67.7 0.1 2.2 2 0 0 2 2 2 1 MCM N-terminal domain MCM2_N PF12619.3 EWM21459.1 - 1.2e-15 57.8 32.4 3.4e-15 56.3 20.4 2.8 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 Mg_chelatase PF01078.16 EWM21459.1 - 4.5e-09 35.7 0.0 1.5e-06 27.5 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EWM21459.1 - 1.8e-06 27.7 0.0 5.2e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EWM21459.1 - 0.0065 15.9 0.0 0.11 11.9 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 EWM21459.1 - 0.027 14.0 0.0 0.1 12.2 0.0 2.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF1635 PF07795.6 EWM21459.1 - 0.4 10.0 2.0 0.81 9.0 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) MUG113 PF13455.1 EWM21460.1 - 0.011 16.1 0.1 0.047 14.1 0.0 2.0 2 0 0 2 2 2 0 Meiotically up-regulated gene 113 BRCT PF00533.21 EWM21460.1 - 0.032 14.3 0.0 0.068 13.3 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Ribosomal_S17 PF00366.15 EWM21461.1 - 1.3e-27 95.6 0.1 2.6e-27 94.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 GDPD PF03009.12 EWM21462.1 - 4.9e-08 32.7 0.0 4.7e-05 23.0 0.0 2.2 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Novirhabdo_Nv PF05554.6 EWM21462.1 - 0.037 13.5 0.0 0.22 11.0 0.0 1.8 1 1 1 2 2 2 0 Viral hemorrhagic septicemia virus non-virion protein TniB PF05621.6 EWM21462.1 - 0.044 12.5 0.1 0.054 12.2 0.1 1.1 1 0 0 1 1 1 0 Bacterial TniB protein F-box-like PF12937.2 EWM21465.1 - 0.0083 15.8 1.4 0.014 15.1 0.5 1.6 2 0 0 2 2 2 1 F-box-like LSM PF01423.17 EWM21466.1 - 4.4e-09 35.7 0.0 5.3e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain Mito_carr PF00153.22 EWM21467.1 - 1.3e-69 229.9 0.2 1.1e-22 79.5 0.0 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein HMD PF03201.11 EWM21467.1 - 0.033 14.1 0.0 6.4 6.7 0.0 2.9 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase E1_DerP2_DerF2 PF02221.10 EWM21469.1 - 5.5e-09 36.3 0.0 7.5e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 EWM21469.1 - 0.00072 19.6 0.1 0.0019 18.2 0.1 1.6 1 1 0 1 1 1 1 ML-like domain DUF1423 PF07227.6 EWM21469.1 - 1.1 7.8 4.8 1.5 7.3 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) UQ_con PF00179.21 EWM21470.1 - 8.8e-47 158.0 0.0 9.9e-47 157.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EWM21470.1 - 0.0064 16.2 0.0 0.0094 15.7 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B zf-DHHC PF01529.15 EWM21471.1 - 2.2e-22 79.3 6.8 2.2e-22 79.3 4.7 1.9 1 1 1 2 2 2 1 DHHC palmitoyltransferase MRAP PF15183.1 EWM21471.1 - 0.2 11.3 0.2 0.2 11.3 0.1 1.8 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family GMC_oxred_N PF00732.14 EWM21472.1 - 4.9e-39 134.2 8.2 1.3e-38 132.8 4.2 2.4 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EWM21472.1 - 4.3e-18 65.9 0.1 8.5e-18 65.0 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EWM21472.1 - 1.2e-08 34.2 1.8 6.1e-08 31.9 0.6 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EWM21472.1 - 0.00089 18.4 1.0 0.00089 18.4 0.7 1.8 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 EWM21472.1 - 0.001 18.2 2.5 0.002 17.2 1.7 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EWM21472.1 - 0.007 15.3 5.2 0.0087 14.9 2.5 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EWM21472.1 - 0.01 15.8 4.6 0.052 13.5 2.2 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EWM21472.1 - 0.019 14.8 2.5 0.036 13.9 1.8 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EWM21472.1 - 0.069 11.6 1.5 0.1 11.0 1.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Abhydrolase_6 PF12697.2 EWM21473.1 - 8.3e-16 58.5 2.7 8.3e-16 58.5 1.9 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EWM21473.1 - 7.4e-09 35.4 0.1 5.6e-08 32.6 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EWM21473.1 - 7.1e-08 32.3 0.2 3.5e-07 30.0 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 EWM21473.1 - 9.7e-05 22.1 0.0 0.00024 20.8 0.0 1.6 1 0 0 1 1 1 1 Cutinase VirJ PF06057.6 EWM21473.1 - 0.012 15.3 0.0 0.22 11.2 0.0 2.3 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) Cupin_6 PF12852.2 EWM21473.1 - 0.19 11.3 3.8 1.4 8.4 0.2 3.1 3 0 0 3 3 3 0 Cupin FUSC PF04632.7 EWM21474.1 - 0.0012 17.4 13.3 0.0014 17.2 9.2 1.1 1 0 0 1 1 1 1 Fusaric acid resistance protein family bZIP_1 PF00170.16 EWM21474.1 - 0.018 15.0 3.6 0.16 11.9 0.2 2.4 1 1 1 2 2 2 0 bZIP transcription factor Shugoshin_N PF07558.6 EWM21474.1 - 0.12 12.0 0.1 0.54 10.0 0.0 1.9 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region ADIP PF11559.3 EWM21474.1 - 1.7 8.5 18.3 6.5 6.6 12.7 1.8 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.4 EWM21474.1 - 1.9 7.3 14.6 2.9 6.7 10.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 EWM21474.1 - 3.1 6.7 11.7 5.1 6.0 8.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.8 EWM21474.1 - 6.5 7.1 14.7 1.4 9.3 7.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF972) DUF3702 PF12486.3 EWM21475.1 - 0.019 14.6 2.2 0.042 13.5 1.5 1.5 1 0 0 1 1 1 0 ImpA domain protein PH PF00169.24 EWM21475.1 - 0.046 13.9 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 PH domain FCH PF00611.18 EWM21475.1 - 0.14 12.4 0.0 0.14 12.4 0.0 2.8 3 0 0 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain PRCC PF10253.4 EWM21476.1 - 9.5e-06 26.4 9.4 9.5e-06 26.4 6.5 3.6 2 2 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting Myosin_head PF00063.16 EWM21477.1 - 1.1e-187 625.2 0.0 2.3e-187 624.1 0.0 1.6 2 0 0 2 2 2 1 Myosin head (motor domain) AAA_22 PF13401.1 EWM21477.1 - 0.0029 17.7 0.9 0.016 15.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EWM21477.1 - 0.0038 18.0 0.7 0.022 15.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain KaiC PF06745.8 EWM21477.1 - 0.023 13.7 0.2 0.023 13.7 0.1 2.0 2 0 0 2 2 2 0 KaiC MobB PF03205.9 EWM21477.1 - 0.11 12.2 0.5 0.57 9.8 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EWM21477.1 - 0.34 11.2 6.9 0.13 12.5 0.2 3.4 2 1 0 2 2 2 0 AAA domain V_ATPase_I PF01496.14 EWM21477.1 - 2 6.1 20.6 3 5.5 14.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cytochrom_B561 PF03188.11 EWM21479.1 - 0.0013 18.5 8.8 0.015 15.1 6.1 2.5 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DUF998 PF06197.8 EWM21479.1 - 0.016 14.5 5.6 0.014 14.7 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF998) DUF2306 PF10067.4 EWM21479.1 - 0.43 10.7 5.0 0.45 10.6 0.0 2.8 2 1 0 2 2 2 0 Predicted membrane protein (DUF2306) MRAP PF15183.1 EWM21479.1 - 0.76 9.4 6.9 1.5 8.4 0.0 2.8 2 1 0 2 2 2 0 Melanocortin-2 receptor accessory protein family Ni_hydr_CYTB PF01292.15 EWM21479.1 - 4.3 6.6 11.9 0.67 9.3 3.7 2.1 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 tRNA-synt_2b PF00587.20 EWM21480.1 - 6.6e-59 198.3 0.1 1.1e-58 197.6 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EWM21480.1 - 1.5e-17 63.2 0.0 3.7e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain WHEP-TRS PF00458.15 EWM21480.1 - 4.2e-09 35.9 1.5 9.9e-09 34.7 1.0 1.7 1 0 0 1 1 1 1 WHEP-TRS domain Sigma54_AID PF00309.15 EWM21480.1 - 0.39 10.2 0.9 0.69 9.4 0.1 1.8 2 0 0 2 2 2 0 Sigma-54 factor, Activator interacting domain (AID) Peptidase_S8 PF00082.17 EWM21481.1 - 3.7e-39 134.5 0.0 5.8e-33 114.2 0.0 2.2 2 0 0 2 2 2 2 Subtilase family DUF4237 PF14021.1 EWM21481.1 - 0.032 14.4 0.0 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4237) GAPT PF11770.3 EWM21481.1 - 0.22 11.2 0.0 0.43 10.2 0.0 1.4 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) Notch PF00066.12 EWM21481.1 - 3 8.1 12.6 0.45 10.8 5.5 2.1 2 0 0 2 2 2 0 LNR domain Pkinase PF00069.20 EWM21482.1 - 1.4e-66 224.3 0.0 2.4e-66 223.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM21482.1 - 2.1e-31 108.9 0.0 3.1e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 EWM21482.1 - 3.4e-22 76.0 0.1 1.4e-09 36.5 0.0 4.5 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 EWM21482.1 - 2.3e-19 69.2 0.5 2.4e-11 43.5 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EWM21482.1 - 3.3e-19 68.2 0.6 2.7e-09 36.4 0.2 3.7 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 EWM21482.1 - 2.9e-17 60.9 0.0 2.6e-05 23.7 0.0 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 EWM21482.1 - 5.9e-17 60.1 0.7 1.6e-06 27.1 0.0 4.3 4 0 0 4 4 4 3 EF hand Kdo PF06293.9 EWM21482.1 - 1.5e-07 30.7 0.5 3.7e-07 29.4 0.3 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EWM21482.1 - 0.00057 19.2 0.2 0.0012 18.2 0.1 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL SPARC_Ca_bdg PF10591.4 EWM21482.1 - 0.0016 18.4 0.0 0.044 13.8 0.0 2.7 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EWM21482.1 - 0.0051 16.5 0.1 0.38 10.5 0.0 2.5 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand APH PF01636.18 EWM21482.1 - 0.0069 16.1 0.3 2.1 8.0 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family EF-hand_9 PF14658.1 EWM21482.1 - 0.021 14.7 0.0 1.6 8.6 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain Kinase-like PF14531.1 EWM21482.1 - 0.046 12.6 0.0 0.19 10.6 0.0 1.9 1 1 1 2 2 2 0 Kinase-like Pkinase PF00069.20 EWM21483.1 - 3.9e-63 213.0 0.0 6.3e-63 212.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM21483.1 - 1.8e-30 105.9 0.0 2.6e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 EWM21483.1 - 2e-22 76.7 0.1 1.2e-09 36.7 0.0 4.5 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 EWM21483.1 - 1.7e-19 69.6 0.5 2.1e-11 43.7 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EWM21483.1 - 2.1e-19 68.8 0.6 2.3e-09 36.6 0.2 3.7 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 EWM21483.1 - 1.7e-17 61.6 0.0 2.2e-05 23.9 0.0 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 EWM21483.1 - 3.5e-17 60.8 0.7 1.4e-06 27.3 0.0 4.4 4 0 0 4 4 4 3 EF hand Kdo PF06293.9 EWM21483.1 - 2.7e-07 29.8 1.0 5.9e-07 28.7 0.7 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EWM21483.1 - 0.00055 19.3 0.2 0.001 18.4 0.1 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL SPARC_Ca_bdg PF10591.4 EWM21483.1 - 0.0013 18.7 0.0 0.039 13.9 0.0 2.7 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EWM21483.1 - 0.004 16.8 0.1 0.33 10.7 0.0 2.4 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand APH PF01636.18 EWM21483.1 - 0.0059 16.3 0.4 1.8 8.2 0.0 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family EF-hand_9 PF14658.1 EWM21483.1 - 0.015 15.1 0.0 1.4 8.9 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain Kinase-like PF14531.1 EWM21483.1 - 0.084 11.8 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like GTP_EFTU PF00009.22 EWM21485.1 - 1.3e-56 191.0 0.0 1.8e-56 190.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EWM21485.1 - 1.6e-35 121.2 0.4 4.3e-35 119.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EWM21485.1 - 1.2e-17 63.7 1.0 2.8e-17 62.5 0.7 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EWM21485.1 - 4e-05 23.5 0.0 0.00082 19.3 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EWM21485.1 - 7.7e-05 22.2 0.4 0.0002 20.9 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 EWM21485.1 - 0.016 15.7 0.2 0.43 11.0 0.2 2.5 1 1 0 1 1 1 0 Miro-like protein Gtr1_RagA PF04670.7 EWM21485.1 - 0.021 13.9 0.0 0.087 11.9 0.0 1.9 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Semialdhyde_dhC PF02774.13 EWM21485.1 - 0.026 14.3 0.5 0.056 13.2 0.1 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain FlpD PF02662.11 EWM21485.1 - 0.042 13.5 0.0 0.67 9.6 0.0 2.2 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit Abhydrolase_3 PF07859.8 EWM21486.1 - 3.8e-58 196.5 0.4 4.9e-58 196.1 0.3 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EWM21486.1 - 3.9e-08 32.4 0.6 8.3e-08 31.3 0.4 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EWM21486.1 - 1.5e-07 31.2 0.1 2.4e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 EWM21486.1 - 1e-06 27.7 0.0 1.4e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 EWM21486.1 - 5.3e-05 22.5 0.0 0.049 12.8 0.1 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 EWM21486.1 - 0.0001 21.2 0.0 0.00017 20.5 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme BAAT_C PF08840.6 EWM21486.1 - 0.1 12.2 0.0 1.2 8.8 0.0 2.3 3 0 0 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF4279 PF14106.1 EWM21487.1 - 0.036 13.9 0.2 0.18 11.7 0.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4279) Gal-bind_lectin PF00337.17 EWM21490.1 - 0.0013 18.0 0.0 0.0029 16.9 0.0 1.5 2 0 0 2 2 2 1 Galactoside-binding lectin RRM_6 PF14259.1 EWM21490.1 - 0.0029 17.5 0.0 0.0062 16.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EWM21490.1 - 0.0049 16.4 0.0 0.012 15.2 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM21490.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Histone PF00125.19 EWM21492.1 - 1.7e-22 79.3 0.1 2.2e-22 78.9 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EWM21492.1 - 0.00095 19.1 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone zf-DHHC PF01529.15 EWM21494.1 - 7.1e-27 93.8 11.9 7.1e-27 93.8 8.3 1.4 1 1 0 1 1 1 1 DHHC palmitoyltransferase Wzy_C PF04932.10 EWM21494.1 - 0.029 14.1 0.2 4.5 7.0 0.8 2.1 2 0 0 2 2 2 0 O-Antigen ligase SUV3_C PF12513.3 EWM21495.1 - 1e-14 53.6 0.2 2.4e-14 52.4 0.1 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 EWM21495.1 - 8.3e-11 41.5 0.0 1.6e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Zot PF05707.7 EWM21495.1 - 0.014 14.8 0.0 0.027 13.9 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) TK PF00265.13 EWM21495.1 - 0.085 12.4 0.0 0.19 11.2 0.0 1.5 1 1 0 1 1 1 0 Thymidine kinase Band_7 PF01145.20 EWM21496.1 - 9.7e-28 97.2 0.3 1.4e-27 96.7 0.2 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EWM21496.1 - 0.01 15.3 0.2 0.021 14.3 0.1 1.6 1 0 0 1 1 1 0 SPFH domain-Band 7 family RNase_P_Rpp14 PF01900.14 EWM21496.1 - 0.023 14.6 0.0 0.05 13.5 0.0 1.6 1 1 0 1 1 1 0 Rpp14/Pop5 family Nit_Regul_Hom PF10126.4 EWM21496.1 - 0.062 13.0 0.3 0.13 12.0 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII Nuc_sug_transp PF04142.10 EWM21497.1 - 3.4e-82 275.2 8.7 3.4e-82 275.2 6.0 1.8 2 0 0 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.15 EWM21497.1 - 3.9e-08 33.3 6.7 3.9e-08 33.3 4.6 2.7 2 1 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 EWM21497.1 - 4.8e-07 29.9 1.0 4.8e-07 29.9 0.7 2.9 3 0 0 3 3 3 1 Multidrug resistance efflux transporter UAA PF08449.6 EWM21497.1 - 2.8e-06 26.4 13.0 2.8e-06 26.4 9.0 1.6 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 EWM21497.1 - 5.4e-06 26.1 27.6 0.00043 19.9 7.0 2.6 2 1 0 2 2 2 2 Triose-phosphate Transporter family DUF1914 PF08932.5 EWM21497.1 - 0.028 14.4 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1914) DUF202 PF02656.10 EWM21497.1 - 1.2 9.3 5.0 0.48 10.6 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF202) SAPS PF04499.10 EWM21498.1 - 1.2e-13 50.5 0.0 2.6e-07 29.6 0.0 4.4 4 1 1 5 5 5 4 SIT4 phosphatase-associated protein RTC PF01137.16 EWM21499.1 - 1.9e-32 111.9 0.0 8.6e-22 77.0 0.3 2.6 3 0 0 3 3 3 2 RNA 3'-terminal phosphate cyclase 2_5_RNA_ligase2 PF13563.1 EWM21499.1 - 3.8e-28 98.1 0.1 6.6e-28 97.3 0.1 1.4 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily DNA_repr_REX1B PF14966.1 EWM21500.1 - 6e-24 84.2 1.0 1.2e-23 83.2 0.7 1.5 1 0 0 1 1 1 1 DNA repair REX1-B ABC_tran PF00005.22 EWM21501.1 - 5.8e-14 52.5 0.1 6.2e-13 49.2 0.1 2.4 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EWM21501.1 - 2.9e-13 50.4 0.0 2.1e-06 27.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EWM21501.1 - 6.8e-06 25.3 0.0 0.017 14.1 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EWM21501.1 - 0.00015 21.2 0.0 0.00028 20.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 EWM21501.1 - 0.0074 15.5 0.1 3.8 6.6 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EWM21501.1 - 0.012 14.8 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 EWM21501.1 - 0.017 14.5 0.2 0.061 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EWM21501.1 - 0.033 14.1 0.8 0.063 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.1 EWM21501.1 - 0.078 13.2 0.3 0.14 12.4 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EWM21501.1 - 0.081 13.7 1.4 0.22 12.3 0.9 2.0 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EWM21501.1 - 0.082 12.5 0.4 1.5 8.5 0.1 2.2 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.1 EWM21501.1 - 0.1 12.7 0.3 0.63 10.1 0.2 2.2 1 1 0 1 1 1 0 AAA domain Arf PF00025.16 EWM21501.1 - 0.14 11.3 0.1 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family DUF3584 PF12128.3 EWM21501.1 - 0.19 9.0 0.1 0.27 8.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_13 PF13166.1 EWM21501.1 - 0.19 10.1 0.0 0.26 9.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain Nbs1_C PF08599.5 EWM21501.1 - 0.23 11.4 3.0 1 9.3 0.8 2.4 2 0 0 2 2 2 0 DNA damage repair protein Nbs1 tRNA_SAD PF07973.9 EWM21502.1 - 1.3e-08 34.5 1.0 3e-08 33.4 0.7 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.14 EWM21502.1 - 3.2e-06 25.7 0.0 3.8e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) Apolipoprotein PF01442.13 EWM21504.1 - 0.0051 16.3 2.6 0.37 10.2 1.8 2.2 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Snapin_Pallidin PF14712.1 EWM21504.1 - 0.0065 16.7 4.0 0.021 15.1 0.4 2.7 2 1 1 3 3 3 1 Snapin/Pallidin TMPIT PF07851.8 EWM21504.1 - 0.019 14.0 1.0 0.019 14.0 0.7 1.7 1 1 1 2 2 2 0 TMPIT-like protein DUF1664 PF07889.7 EWM21504.1 - 0.026 14.3 3.2 6.7 6.5 0.0 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) AAA_13 PF13166.1 EWM21504.1 - 0.037 12.4 1.8 0.044 12.2 1.2 1.1 1 0 0 1 1 1 0 AAA domain Mt_ATP-synt_B PF05405.9 EWM21504.1 - 0.062 12.7 2.5 6.3 6.2 0.0 2.4 1 1 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Sec20 PF03908.8 EWM21504.1 - 0.065 12.9 0.3 0.4 10.4 0.0 2.2 2 1 0 2 2 2 0 Sec20 DHC_N1 PF08385.7 EWM21504.1 - 0.072 11.4 1.0 0.088 11.1 0.7 1.1 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 COG5 PF10392.4 EWM21504.1 - 0.094 12.6 3.6 0.26 11.2 0.2 2.7 2 1 1 3 3 3 0 Golgi transport complex subunit 5 Prefoldin_3 PF13758.1 EWM21504.1 - 0.16 11.7 3.3 0.18 11.5 0.2 2.6 1 1 0 2 2 2 0 Prefoldin subunit RD3 PF14473.1 EWM21504.1 - 0.16 11.4 2.6 0.13 11.7 0.5 1.8 2 0 0 2 2 2 0 RD3 protein Syntaxin-6_N PF09177.6 EWM21504.1 - 0.17 12.3 6.2 2.2 8.7 0.5 2.8 1 1 0 2 2 2 0 Syntaxin 6, N-terminal Synaptobrevin PF00957.16 EWM21504.1 - 0.18 11.4 1.1 2.5 7.7 0.0 3.0 2 2 1 3 3 3 0 Synaptobrevin DUF2450 PF10475.4 EWM21504.1 - 0.18 10.6 2.5 0.44 9.3 1.6 1.8 1 1 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) MscS_porin PF12795.2 EWM21504.1 - 0.25 10.6 2.7 0.22 10.8 0.2 2.0 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain V-SNARE PF05008.10 EWM21504.1 - 0.29 11.3 8.7 0.32 11.1 1.5 3.1 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus RmuC PF02646.11 EWM21504.1 - 0.31 9.8 3.2 0.43 9.3 0.2 2.3 1 1 0 2 2 2 0 RmuC family FimP PF09766.4 EWM21504.1 - 0.42 9.6 5.5 0.046 12.7 0.7 1.6 2 0 0 2 2 2 0 Fms-interacting protein HisKA_3 PF07730.8 EWM21504.1 - 0.57 10.5 10.9 7.1 7.0 1.4 4.6 1 1 3 4 4 4 0 Histidine kinase GreA_GreB_N PF03449.10 EWM21504.1 - 0.63 10.1 5.8 25 5.0 0.1 3.6 3 0 0 3 3 3 0 Transcription elongation factor, N-terminal DUF3135 PF11333.3 EWM21504.1 - 0.63 10.2 3.5 4 7.6 0.3 3.2 2 1 1 4 4 4 0 Protein of unknown function (DUF3135) DivIVA PF05103.8 EWM21504.1 - 1.1 9.2 6.7 4.1 7.4 1.4 2.7 1 1 1 2 2 2 0 DivIVA protein Cep57_MT_bd PF06657.8 EWM21504.1 - 1.6 8.7 6.6 3.8 7.5 0.5 2.6 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Rho_Binding PF08912.6 EWM21504.1 - 2.1 8.7 6.3 7.2 6.9 0.3 3.4 2 1 2 4 4 4 0 Rho Binding Striatin PF08232.7 EWM21504.1 - 2.5 8.4 8.5 17 5.7 5.7 2.2 1 1 0 1 1 1 0 Striatin family V_ATPase_I PF01496.14 EWM21504.1 - 5.2 4.8 6.7 3.1 5.5 1.3 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family HR1 PF02185.11 EWM21504.1 - 5.3 6.8 9.6 8 6.2 0.1 3.7 5 0 0 5 5 4 0 Hr1 repeat ING PF12998.2 EWM21504.1 - 6.2 7.1 8.5 6.3e+02 0.7 5.9 2.6 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Spc7 PF08317.6 EWM21504.1 - 8.8 4.8 8.0 12 4.3 4.6 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein Condensin2nSMC PF12422.3 EWM21506.1 - 2e-47 160.7 0.0 4.2e-47 159.6 0.0 1.6 1 0 0 1 1 1 1 Condensin II non structural maintenance of chromosomes subunit HEAT PF02985.17 EWM21506.1 - 5.3e-07 29.1 5.5 0.1 12.7 0.1 5.3 4 0 0 4 4 4 3 HEAT repeat Adaptin_N PF01602.15 EWM21506.1 - 0.11 10.8 0.1 0.19 10.0 0.0 1.3 1 0 0 1 1 1 0 Adaptin N terminal region HSF_DNA-bind PF00447.12 EWM21507.1 - 1.5e-20 73.2 0.1 4.6e-20 71.7 0.0 1.8 2 0 0 2 2 2 1 HSF-type DNA-binding Pribosyltran PF00156.22 EWM21508.1 - 2.9e-08 33.4 0.0 4.7e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.1 EWM21508.1 - 0.016 14.9 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain FAD_binding_1 PF00667.15 EWM21508.1 - 0.11 11.9 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Peptidase_A22B PF04258.8 EWM21510.1 - 1.3e-77 261.2 4.0 1.9e-77 260.6 2.8 1.2 1 0 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 EWM21510.1 - 3.2e-06 26.5 0.7 3.2e-06 26.5 0.5 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1119) MAM33 PF02330.11 EWM21511.1 - 1.5e-12 47.7 14.3 1.2e-10 41.4 9.9 2.1 1 1 0 1 1 1 1 Mitochondrial glycoprotein AAA PF00004.24 EWM21512.1 - 1.3e-52 177.4 0.0 2e-39 134.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 EWM21512.1 - 1e-06 27.7 0.0 0.0072 15.0 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_16 PF13191.1 EWM21512.1 - 1.5e-06 28.3 0.5 0.0038 17.2 0.0 3.4 2 1 0 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 EWM21512.1 - 2.2e-06 27.6 0.0 3.6e-05 23.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EWM21512.1 - 9.7e-06 25.7 1.3 0.21 11.7 0.3 4.1 2 2 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EWM21512.1 - 1.8e-05 24.3 0.6 0.022 14.5 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain Mg_chelatase PF01078.16 EWM21512.1 - 4.9e-05 22.5 0.8 0.0032 16.6 0.0 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EWM21512.1 - 8e-05 22.2 0.0 0.091 12.3 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EWM21512.1 - 9e-05 21.9 0.0 0.25 10.7 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_5 PF07728.9 EWM21512.1 - 0.00013 21.7 0.3 0.011 15.5 0.1 3.4 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EWM21512.1 - 0.00017 20.7 0.1 0.13 11.3 0.0 2.7 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EWM21512.1 - 0.00019 21.4 0.1 0.77 9.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain CDC48_2 PF02933.12 EWM21512.1 - 0.0014 18.2 0.4 0.0089 15.6 0.0 2.3 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_14 PF13173.1 EWM21512.1 - 0.003 17.4 0.0 0.37 10.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EWM21512.1 - 0.0045 17.7 0.0 1.9 9.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EWM21512.1 - 0.0071 16.2 0.0 1.4 8.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 EWM21512.1 - 0.01 15.3 0.0 4.8 6.6 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain CPT PF07931.7 EWM21512.1 - 0.015 14.8 0.0 0.17 11.5 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein RNA_helicase PF00910.17 EWM21512.1 - 0.016 15.3 0.0 0.21 11.7 0.0 2.6 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.22 EWM21512.1 - 0.019 15.2 0.1 0.065 13.5 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.1 EWM21512.1 - 0.028 13.8 5.2 19 4.6 0.1 3.9 2 2 1 4 4 4 0 AAA domain AAA_11 PF13086.1 EWM21512.1 - 0.035 13.6 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EWM21512.1 - 0.035 14.3 0.1 1.8 8.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EWM21512.1 - 0.036 13.1 0.2 0.53 9.3 0.0 2.5 2 0 0 2 2 2 0 KaiC KTI12 PF08433.5 EWM21512.1 - 0.049 12.8 0.0 11 5.1 0.0 2.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Parvo_NS1 PF01057.12 EWM21512.1 - 0.061 12.1 0.0 3.9 6.2 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 CDC48_N PF02359.13 EWM21512.1 - 0.091 12.7 0.0 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain Rad17 PF03215.10 EWM21512.1 - 0.2 10.3 0.0 0.36 9.4 0.0 1.4 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein SBBP PF06739.6 EWM21515.1 - 2.4e-21 75.2 44.9 0.00035 20.2 0.2 7.5 7 0 0 7 7 7 7 Beta-propeller repeat DUF4346 PF14251.1 EWM21515.1 - 0.0018 18.0 0.0 3.5 7.3 0.0 3.5 3 0 0 3 3 3 2 Domain of unknown function (DUF4346) Peptidase_M26_N PF05342.9 EWM21515.1 - 0.59 9.0 1.9 9.3 5.1 0.0 3.4 5 0 0 5 5 5 0 M26 IgA1-specific Metallo-endopeptidase N-terminal region KH_1 PF00013.24 EWM21516.1 - 3e-29 100.4 8.9 1.3e-14 53.5 1.5 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 EWM21516.1 - 2.4e-21 74.9 8.9 1.5e-10 40.4 1.8 2.6 2 0 0 2 2 2 2 KH domain KH_4 PF13083.1 EWM21516.1 - 3.2e-06 26.6 4.7 0.0017 17.9 0.1 3.1 3 0 0 3 3 3 2 KH domain KH_2 PF07650.12 EWM21516.1 - 2.3e-05 23.8 0.5 0.012 15.1 0.0 2.5 2 0 0 2 2 2 2 KH domain OmpH PF03938.9 EWM21516.1 - 0.03 14.2 3.8 0.086 12.7 2.7 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) SDA1 PF05285.7 EWM21516.1 - 0.097 11.9 9.9 0.11 11.7 6.9 1.1 1 0 0 1 1 1 0 SDA1 KH_5 PF13184.1 EWM21516.1 - 0.15 11.8 1.5 12 5.7 0.2 2.4 2 0 0 2 2 2 0 NusA-like KH domain SGL PF08450.7 EWM21517.1 - 2.6e-36 125.2 0.0 4.6e-36 124.4 0.0 1.3 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 EWM21517.1 - 0.0033 17.3 2.4 14 5.8 0.0 3.9 3 0 0 3 3 3 2 NHL repeat Str_synth PF03088.11 EWM21517.1 - 0.014 15.4 0.0 2 8.4 0.0 3.1 3 0 0 3 3 3 0 Strictosidine synthase Arylesterase PF01731.15 EWM21517.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Arylesterase Abhydrolase_5 PF12695.2 EWM21518.1 - 3.7e-15 55.9 0.0 6.9e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EWM21518.1 - 8.7e-10 38.8 2.9 2.6e-09 37.3 2.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EWM21518.1 - 2.5e-06 27.1 0.0 2e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase_phd PF10503.4 EWM21518.1 - 4.1e-06 26.2 0.0 8.4e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_1 PF00561.15 EWM21518.1 - 3.4e-05 23.5 0.1 0.00015 21.4 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EWM21518.1 - 4.8e-05 22.6 0.0 0.035 13.3 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EWM21518.1 - 6.9e-05 22.5 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EWM21518.1 - 0.00082 18.8 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Putative esterase DUF2974 PF11187.3 EWM21518.1 - 0.00082 18.7 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) DLH PF01738.13 EWM21518.1 - 0.0018 17.6 0.0 0.0032 16.7 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.8 EWM21518.1 - 0.039 13.3 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Lipase_3 PF01764.20 EWM21518.1 - 0.067 12.8 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) BAAT_C PF08840.6 EWM21518.1 - 0.24 11.0 0.0 1.7 8.3 0.0 2.0 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal TIG PF01833.19 EWM21519.1 - 9.4e-27 92.8 2.7 2.9e-08 33.5 0.1 3.9 3 0 0 3 3 3 3 IPT/TIG domain FG-GAP PF01839.18 EWM21519.1 - 1.5e-21 75.4 51.2 1.3e-06 27.8 1.8 6.8 6 0 0 6 6 6 6 FG-GAP repeat FG-GAP_2 PF14312.1 EWM21519.1 - 1.6e-09 37.6 30.9 0.0094 15.9 1.2 5.8 5 0 0 5 5 5 5 FG-GAP repeat VCBS PF13517.1 EWM21519.1 - 4.2e-06 27.0 24.8 0.011 16.0 3.0 5.0 3 2 2 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TRP PF06011.7 EWM21519.1 - 4.8e-05 22.1 0.4 4.8e-05 22.1 0.3 1.8 2 0 0 2 2 2 1 Transient receptor potential (TRP) ion channel GCC2_GCC3 PF07699.8 EWM21519.1 - 0.00032 20.2 2.4 0.00032 20.2 1.7 2.5 2 0 0 2 2 2 1 GCC2 and GCC3 Sarcoglycan_2 PF05510.8 EWM21519.1 - 0.1 10.8 0.1 0.18 10.1 0.1 1.2 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon zf-C3HC4_3 PF13920.1 EWM21520.1 - 6e-06 25.8 9.2 9.5e-06 25.2 6.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 EWM21520.1 - 0.0003 20.2 2.9 0.00062 19.2 2.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.1 EWM21520.1 - 0.015 15.3 6.5 0.033 14.2 4.5 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EWM21520.1 - 0.017 14.8 10.3 0.032 13.9 7.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 EWM21520.1 - 0.14 11.8 6.0 0.4 10.3 4.3 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SRP54 PF00448.17 EWM21521.1 - 2.9e-77 258.5 0.1 4.3e-77 258.0 0.1 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EWM21521.1 - 7.3e-26 90.4 10.2 2.1e-25 88.9 0.1 3.1 3 0 0 3 3 3 1 Signal peptide binding domain SRP54_N PF02881.14 EWM21521.1 - 5.9e-15 55.1 0.5 2.5e-14 53.1 0.5 1.9 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.1 EWM21521.1 - 6.8e-09 35.7 0.0 1.5e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 EWM21521.1 - 6.8e-08 32.1 0.0 2.7e-07 30.2 0.0 1.9 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EWM21521.1 - 2.9e-06 27.0 0.1 9.9e-06 25.3 0.0 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EWM21521.1 - 4.3e-05 23.6 0.1 0.00018 21.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EWM21521.1 - 7.1e-05 22.4 0.2 0.00018 21.1 0.1 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EWM21521.1 - 0.00011 21.3 0.1 0.0002 20.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_31 PF13614.1 EWM21521.1 - 0.0011 18.9 0.0 0.96 9.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain SRPRB PF09439.5 EWM21521.1 - 0.003 16.8 0.6 3.1 6.9 0.1 3.1 1 1 1 3 3 3 1 Signal recognition particle receptor beta subunit ArgK PF03308.11 EWM21521.1 - 0.0032 16.2 0.2 0.034 12.9 0.1 2.3 1 1 0 1 1 1 1 ArgK protein AAA_17 PF13207.1 EWM21521.1 - 0.0064 17.2 0.0 0.015 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EWM21521.1 - 0.0075 16.0 0.0 0.023 14.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain MMR_HSR1 PF01926.18 EWM21521.1 - 0.0084 16.0 0.0 0.027 14.4 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EWM21521.1 - 0.0093 15.9 0.0 0.029 14.3 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.15 EWM21521.1 - 0.012 15.2 0.6 0.027 14.1 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase PduV-EutP PF10662.4 EWM21521.1 - 0.016 14.7 0.2 3.7 7.0 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CobN-Mg_chel PF02514.11 EWM21521.1 - 0.027 11.8 0.1 0.037 11.4 0.0 1.1 1 0 0 1 1 1 0 CobN/Magnesium Chelatase CbiA PF01656.18 EWM21521.1 - 0.04 13.3 0.0 0.15 11.4 0.0 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_10 PF12846.2 EWM21521.1 - 0.074 12.4 0.1 0.27 10.6 0.0 2.1 1 1 0 1 1 1 0 AAA-like domain DUF373 PF04123.8 EWM21521.1 - 0.099 11.6 0.5 0.15 11.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Arf PF00025.16 EWM21521.1 - 0.11 11.7 0.1 0.29 10.3 0.0 1.7 2 0 0 2 2 1 0 ADP-ribosylation factor family ResIII PF04851.10 EWM21521.1 - 0.16 11.7 0.5 0.4 10.4 0.3 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit NB-ARC PF00931.17 EWM21521.1 - 0.35 9.6 5.3 0.59 8.9 0.2 2.4 2 1 0 2 2 2 0 NB-ARC domain DUF1179 PF06678.6 EWM21522.1 - 0.097 12.9 1.8 0.89 9.8 0.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1179) ETS_PEA3_N PF04621.8 EWM21522.1 - 0.4 9.8 2.9 0.49 9.5 2.0 1.1 1 0 0 1 1 1 0 PEA3 subfamily ETS-domain transcription factor N terminal domain FGGY_C PF02782.11 EWM21523.1 - 1.4e-15 57.4 0.0 2.5e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EWM21523.1 - 0.00042 19.7 0.0 0.15 11.3 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain PsbP PF01789.11 EWM21524.1 - 4.4e-07 29.5 0.0 6.2e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 PsbP Acetyltransf_7 PF13508.1 EWM21526.1 - 2.7e-05 24.2 0.0 4.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EWM21526.1 - 7.3e-05 22.7 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DHQ_synthase PF01761.15 EWM21531.1 - 3.2e-05 22.9 0.0 6.2e-05 22.0 0.0 1.4 1 1 0 1 1 1 1 3-dehydroquinate synthase OGFr_III PF04680.8 EWM21532.1 - 8.7 6.6 9.2 18 5.6 4.3 2.3 2 0 0 2 2 2 0 Opioid growth factor receptor repeat GRIP PF01465.15 EWM21533.1 - 0.00013 21.3 0.0 0.00032 20.1 0.0 1.7 1 0 0 1 1 1 1 GRIP domain Cast PF10174.4 EWM21533.1 - 0.0022 16.1 18.9 0.0022 16.1 13.1 2.3 2 0 0 2 2 2 1 RIM-binding protein of the cytomatrix active zone DUF1848 PF08902.6 EWM21533.1 - 0.28 10.6 1.7 0.34 10.3 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1848) DHHA1 PF02272.14 EWM21533.1 - 0.5 10.0 0.0 0.5 10.0 0.0 3.1 3 0 0 3 3 3 0 DHHA1 domain Laminin_II PF06009.7 EWM21533.1 - 0.56 9.9 11.7 0.26 11.0 5.7 2.1 2 0 0 2 2 2 0 Laminin Domain II IncA PF04156.9 EWM21533.1 - 0.89 9.1 38.3 0.11 12.0 12.3 2.8 3 0 0 3 3 3 0 IncA protein THP2 PF09432.5 EWM21533.1 - 0.93 9.3 11.4 0.037 13.8 1.4 2.7 2 1 1 3 3 3 0 Tho complex subunit THP2 Atg14 PF10186.4 EWM21533.1 - 1.3 7.9 24.9 2.6 6.8 9.9 2.3 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 NPV_P10 PF05531.7 EWM21533.1 - 4 7.7 14.3 1.2 9.3 1.1 3.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Viral_env_E26 PF11050.3 EWM21533.1 - 4.4 6.4 11.2 1 8.5 3.1 2.8 3 0 0 3 3 3 0 Virus envelope protein E26 SPX PF03105.14 EWM21533.1 - 5.3 6.7 23.4 5.9e+02 -0.0 16.3 2.2 1 1 0 1 1 1 0 SPX domain TPR_10 PF13374.1 EWM21535.1 - 0.04 13.8 1.4 4.6 7.3 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 EWM21535.1 - 0.065 13.6 5.3 0.21 12.0 1.4 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.12 EWM21535.1 - 0.19 12.0 3.4 0.21 11.8 0.3 2.1 2 1 0 2 2 2 0 Bacterial transcriptional activator domain TPR_14 PF13428.1 EWM21535.1 - 0.2 12.4 3.4 1.5 9.6 0.3 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 EWM21535.1 - 0.21 11.9 1.0 4.5 7.6 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat AMP-binding PF00501.23 EWM21536.1 - 1.9e-10 39.6 0.0 2.4e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme PPR PF01535.15 EWM21537.1 - 0.018 14.9 0.4 0.058 13.3 0.0 1.9 2 0 0 2 2 2 0 PPR repeat PPR_3 PF13812.1 EWM21537.1 - 0.18 12.1 0.4 0.82 10.1 0.0 2.2 3 0 0 3 3 3 0 Pentatricopeptide repeat domain PPR_3 PF13812.1 EWM21538.1 - 1.2e-25 87.5 0.3 7.4e-08 32.0 0.0 4.8 5 0 0 5 5 5 4 Pentatricopeptide repeat domain PPR_2 PF13041.1 EWM21538.1 - 4.4e-22 77.8 0.0 1.6e-08 34.3 0.0 4.1 1 1 3 4 4 4 3 PPR repeat family PPR PF01535.15 EWM21538.1 - 2.7e-18 64.5 0.1 2.4e-05 23.9 0.0 4.4 5 0 0 5 5 5 3 PPR repeat PPR_1 PF12854.2 EWM21538.1 - 3.6e-08 32.7 0.0 0.0005 19.5 0.0 3.9 5 0 0 5 5 5 2 PPR repeat TPR_14 PF13428.1 EWM21538.1 - 0.00027 21.3 0.3 2.8 8.8 0.1 4.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EWM21538.1 - 0.0015 18.1 0.0 0.94 9.4 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EWM21538.1 - 0.01 15.7 0.4 3.1 7.8 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat MRP-S27 PF10037.4 EWM21538.1 - 0.014 14.3 0.0 0.084 11.7 0.0 1.8 1 1 1 2 2 2 0 Mitochondrial 28S ribosomal protein S27 TPR_16 PF13432.1 EWM21538.1 - 0.014 16.0 2.2 0.21 12.3 0.3 2.9 2 2 1 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 EWM21538.1 - 0.034 14.2 0.1 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EWM21538.1 - 0.048 13.5 0.9 0.57 10.1 0.6 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EWM21538.1 - 0.14 12.1 0.4 39 4.5 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2628 PF10947.3 EWM21542.1 - 0.68 9.7 3.5 1.1 9.0 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) Daxx PF03344.10 EWM21543.1 - 0.096 11.1 2.4 0.094 11.1 1.7 1.1 1 0 0 1 1 1 0 Daxx Family Mak16 PF04874.9 EWM21543.1 - 0.41 10.7 11.0 0.56 10.3 7.6 1.2 1 0 0 1 1 1 0 Mak16 protein C-terminal region Sigma70_ner PF04546.8 EWM21543.1 - 0.89 9.1 4.4 1.1 8.8 3.1 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region VID27 PF08553.5 EWM21543.1 - 1.1 7.4 7.1 1.4 7.0 5.0 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein DUF4637 PF15470.1 EWM21543.1 - 1.3 8.6 4.2 1.7 8.2 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF2457 PF10446.4 EWM21543.1 - 8.7 4.9 7.8 14 4.2 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Mito_carr PF00153.22 EWM21544.1 - 2.7e-48 161.6 2.4 1.7e-17 62.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RRN9 PF10680.4 EWM21545.1 - 0.089 12.5 0.1 0.098 12.4 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor Glutaredoxin PF00462.19 EWM21545.1 - 0.84 9.6 2.8 16 5.5 0.9 2.6 2 1 1 3 3 3 0 Glutaredoxin Chalcone PF02431.10 EWM21548.1 - 0.0075 15.6 0.0 0.0083 15.5 0.0 1.0 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Ras PF00071.17 EWM21552.1 - 1.3e-38 131.9 0.8 1.7e-38 131.5 0.6 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EWM21552.1 - 9.2e-12 45.5 0.0 5.4e-11 43.0 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EWM21552.1 - 6.4e-09 35.2 0.1 9.4e-09 34.7 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EWM21552.1 - 5.7e-06 25.9 0.0 6.7e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EWM21552.1 - 1.9e-05 23.9 0.0 2.1e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region U-box PF04564.10 EWM21554.1 - 2.2e-13 49.9 0.0 3.5e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.3 EWM21554.1 - 0.0024 17.3 0.0 0.0036 16.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit NOA36 PF06524.7 EWM21554.1 - 0.14 11.4 0.2 0.14 11.3 0.1 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2890 PF11081.3 EWM21554.1 - 0.29 11.1 9.2 0.48 10.4 6.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Paf1 PF03985.8 EWM21554.1 - 0.34 9.5 4.4 0.4 9.3 3.0 1.1 1 0 0 1 1 1 0 Paf1 SDA1 PF05285.7 EWM21554.1 - 1.4 8.1 8.0 1.9 7.7 5.6 1.1 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.8 EWM21554.1 - 1.8 6.2 8.0 2.1 6.0 5.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.7 EWM21554.1 - 2.9 5.6 8.9 3.7 5.3 6.1 1.1 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 EWM21554.1 - 3.1 7.2 9.2 4.4 6.8 6.4 1.2 1 0 0 1 1 1 0 Nucleoplasmin CDC45 PF02724.9 EWM21554.1 - 4.3 5.2 5.7 4.9 5.0 4.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Myc_N PF01056.13 EWM21554.1 - 8 5.5 7.5 14 4.7 5.2 1.5 1 0 0 1 1 1 0 Myc amino-terminal region GlcNAc PF11397.3 EWM21556.1 - 8.1e-11 41.6 0.0 9.2e-11 41.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) Phage_AlpA PF05930.7 EWM21556.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) COPI_assoc PF08507.5 EWM21558.1 - 1.9e-10 40.5 1.5 2.5e-10 40.1 1.0 1.1 1 0 0 1 1 1 1 COPI associated protein AA_permease PF00324.16 EWM21558.1 - 0.0057 15.0 2.9 0.0057 15.0 2.0 1.9 1 1 1 2 2 2 1 Amino acid permease CTP_transf_1 PF01148.15 EWM21558.1 - 0.11 12.1 5.6 0.15 11.7 3.9 1.1 1 0 0 1 1 1 0 Cytidylyltransferase family PGG PF13962.1 EWM21558.1 - 0.24 11.0 2.4 0.47 10.0 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function EcsB PF05975.7 EWM21558.1 - 0.33 9.3 7.4 0.4 9.0 5.1 1.1 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB MARVEL PF01284.18 EWM21558.1 - 1.2 8.9 12.6 4.1 7.2 3.4 2.1 1 1 1 2 2 2 0 Membrane-associating domain DUF2975 PF11188.3 EWM21558.1 - 1.2 8.8 9.7 0.33 10.6 2.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) SdpI PF13630.1 EWM21558.1 - 7.7 6.3 8.3 12 5.7 3.0 2.3 2 0 0 2 2 2 0 SdpI/YhfL protein family FbpA PF05833.6 EWM21560.1 - 2.2e-27 95.7 0.0 2.4e-27 95.5 0.0 1.0 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) NAD_binding_10 PF13460.1 EWM21561.1 - 3.8e-12 46.6 0.0 8.4e-12 45.4 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EWM21561.1 - 1.3e-08 34.4 0.0 0.00035 19.8 0.1 2.5 2 1 0 2 2 2 2 NmrA-like family Epimerase PF01370.16 EWM21561.1 - 1.9e-05 24.2 0.0 4.2e-05 23.0 0.0 1.6 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EWM21561.1 - 0.0029 17.5 1.2 0.0044 16.9 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 EWM21561.1 - 0.018 14.0 0.3 0.025 13.5 0.2 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase KR PF08659.5 EWM21561.1 - 0.029 14.0 0.4 0.053 13.1 0.3 1.3 1 0 0 1 1 1 0 KR domain Semialdhyde_dh PF01118.19 EWM21561.1 - 0.037 14.3 0.1 0.064 13.5 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EWM21561.1 - 0.045 12.4 0.1 0.066 11.9 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 EWM21561.1 - 0.055 13.3 0.2 0.094 12.6 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.12 EWM21561.1 - 0.095 13.1 0.1 0.22 11.9 0.1 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Abhydrolase_6 PF12697.2 EWM21562.1 - 4e-07 30.1 1.0 4.9e-07 29.8 0.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM21562.1 - 9.9e-07 28.6 0.2 1.2e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EWM21562.1 - 2.3e-06 27.3 0.0 3.8e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 EWM21562.1 - 0.0025 17.4 0.0 0.0042 16.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.9 EWM21562.1 - 0.007 15.6 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Cutinase PF01083.17 EWM21562.1 - 0.012 15.4 0.0 0.023 14.4 0.0 1.5 1 1 0 1 1 1 0 Cutinase LCAT PF02450.10 EWM21562.1 - 0.17 10.8 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase ABC2_membrane PF01061.19 EWM21564.1 - 4.7e-60 202.3 58.5 1.1e-31 109.5 14.2 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EWM21564.1 - 8.4e-19 68.2 0.0 1.3e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 EWM21564.1 - 9.4e-06 24.8 45.7 0.0085 15.1 15.5 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 EWM21564.1 - 0.00014 21.9 0.0 0.51 10.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EWM21564.1 - 0.002 17.5 1.1 0.023 14.0 0.7 2.6 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EWM21564.1 - 0.0027 17.2 0.1 0.007 15.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EWM21564.1 - 0.025 13.7 0.0 0.045 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_28 PF13521.1 EWM21564.1 - 0.068 13.1 0.3 0.12 12.3 0.2 1.4 1 0 0 1 1 1 0 AAA domain Evr1_Alr PF04777.8 EWM21565.1 - 3.3e-14 52.5 0.0 7.6e-14 51.3 0.0 1.6 1 0 0 1 1 1 1 Erv1 / Alr family Thioredoxin PF00085.15 EWM21565.1 - 3.9e-12 45.7 0.0 6.3e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EWM21565.1 - 0.097 12.8 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain Zn_Tnp_IS1595 PF12760.2 EWM21565.1 - 1.5 8.6 7.4 1.7 8.5 1.0 3.2 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Ribosomal_L37 PF08561.5 EWM21566.1 - 8.4e-15 54.1 0.1 1.4e-14 53.4 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 DUF676 PF05057.9 EWM21568.1 - 1.6e-36 125.6 0.0 2.4e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EWM21568.1 - 0.0027 17.4 0.1 0.0068 16.1 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family TPR_19 PF14559.1 EWM21569.1 - 0.00054 20.2 2.5 0.011 16.0 0.4 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EWM21569.1 - 0.0037 17.8 11.8 0.076 13.7 1.3 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EWM21569.1 - 0.0049 16.9 0.1 6.3 7.2 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EWM21569.1 - 0.0056 16.2 2.7 0.031 13.9 0.1 2.8 3 0 0 3 3 3 1 TPR repeat TPR_14 PF13428.1 EWM21569.1 - 0.015 15.8 5.0 0.14 12.8 0.5 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat NARP1 PF12569.3 EWM21569.1 - 0.14 10.8 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Cyt-b5 PF00173.23 EWM21570.1 - 2e-15 56.3 0.0 3.9e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Histone PF00125.19 EWM21571.1 - 5.4e-26 90.5 0.0 6.7e-26 90.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EWM21571.1 - 0.00017 21.5 0.0 0.00022 21.2 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Chloroa_b-bind PF00504.16 EWM21572.1 - 1.5e-30 106.4 0.3 2e-30 106.0 0.2 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Atu4866 PF11512.3 EWM21572.1 - 0.012 15.3 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Agrobacterium tumefaciens protein Atu4866 Hus1 PF04005.7 EWM21573.1 - 2.5e-30 105.4 0.0 2.8e-30 105.2 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Pyr_redox PF00070.22 EWM21574.1 - 2.8e-10 40.4 0.0 2.3e-07 31.1 0.0 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EWM21574.1 - 0.00022 21.3 0.0 0.14 12.1 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EWM21574.1 - 0.00068 19.4 0.0 0.083 12.6 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding AIF_C PF14721.1 EWM21574.1 - 0.046 13.9 0.0 0.29 11.3 0.0 2.1 1 1 1 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term K_oxygenase PF13434.1 EWM21574.1 - 0.15 10.9 0.0 12 4.7 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) PhrC_PhrF PF11131.3 EWM21574.1 - 1.2 8.7 3.2 14 5.3 0.2 3.0 3 0 0 3 3 3 0 Rap-phr extracellular signalling ABC_tran PF00005.22 EWM21575.1 - 1.9e-47 161.0 0.4 7.2e-23 81.4 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_tran_2 PF12848.2 EWM21575.1 - 1.3e-23 82.5 19.1 1.6e-21 75.9 1.2 3.5 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 EWM21575.1 - 2.8e-15 57.0 1.2 0.0035 17.3 0.1 4.3 2 2 1 4 4 4 4 AAA domain AAA_29 PF13555.1 EWM21575.1 - 7.6e-07 28.5 0.2 0.00084 18.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EWM21575.1 - 7.7e-07 29.9 0.6 0.031 15.0 0.0 4.0 4 0 0 4 4 3 2 AAA domain SMC_N PF02463.14 EWM21575.1 - 1.9e-06 27.2 5.7 0.11 11.7 0.0 4.4 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EWM21575.1 - 1.5e-05 24.2 0.5 0.071 12.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 EWM21575.1 - 4.1e-05 24.0 0.1 0.025 15.0 0.0 3.0 2 1 0 2 2 2 1 Miro-like protein Mg_chelatase PF01078.16 EWM21575.1 - 9.8e-05 21.6 0.0 0.65 9.1 0.0 3.3 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA PF00004.24 EWM21575.1 - 0.00018 21.7 0.0 0.52 10.5 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EWM21575.1 - 0.00024 21.4 3.8 0.75 10.1 0.0 3.8 4 0 0 4 4 3 2 AAA domain AAA_22 PF13401.1 EWM21575.1 - 0.00035 20.7 1.7 0.16 12.1 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.1 EWM21575.1 - 0.00071 19.6 4.6 0.14 12.0 0.0 3.3 3 1 0 3 3 3 2 AAA ATPase domain AAA_28 PF13521.1 EWM21575.1 - 0.00087 19.2 0.1 1.2 9.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EWM21575.1 - 0.0014 18.2 0.5 1.7 8.2 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_15 PF13175.1 EWM21575.1 - 0.0032 16.5 0.0 1.5 7.7 0.0 3.6 3 1 0 4 4 4 1 AAA ATPase domain AAA_14 PF13173.1 EWM21575.1 - 0.0033 17.3 0.0 0.68 9.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EWM21575.1 - 0.0033 17.2 1.8 7.6 6.5 0.0 5.0 4 1 0 4 4 4 0 Putative exonuclease SbcCD, C subunit MobB PF03205.9 EWM21575.1 - 0.0048 16.6 0.5 0.58 9.8 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EWM21575.1 - 0.01 15.7 1.2 0.081 12.8 0.0 2.9 2 2 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.1 EWM21575.1 - 0.016 15.0 0.0 9.3 6.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EWM21575.1 - 0.022 14.1 0.8 10 5.4 0.0 3.4 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.18 EWM21575.1 - 0.038 13.8 0.6 0.88 9.3 0.0 2.8 3 0 0 3 3 3 0 Dynamin family RNA_helicase PF00910.17 EWM21575.1 - 0.039 14.1 0.0 5 7.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.1 EWM21575.1 - 0.042 14.1 0.0 0.042 14.1 0.0 4.8 4 2 1 5 5 4 0 AAA domain ATP-synt_ab PF00006.20 EWM21575.1 - 0.043 13.3 0.0 0.76 9.2 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Rad17 PF03215.10 EWM21575.1 - 0.054 12.1 0.0 2.5 6.6 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein IstB_IS21 PF01695.12 EWM21575.1 - 0.094 12.1 0.4 4.5 6.6 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein Atg14 PF10186.4 EWM21575.1 - 0.19 10.6 0.5 0.52 9.2 0.4 1.7 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 AAA_13 PF13166.1 EWM21575.1 - 2.2 6.6 15.7 0.87 7.9 0.0 3.9 4 0 0 4 4 3 0 AAA domain zf-UBP PF02148.14 EWM21576.1 - 1.2e-16 60.5 8.3 3.2e-16 59.1 5.7 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Nol1_Nop2_Fmu PF01189.12 EWM21577.1 - 6.4e-85 284.9 0.0 8.7e-85 284.5 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 EWM21577.1 - 0.00083 19.3 0.1 0.006 16.5 0.0 2.2 1 1 1 2 2 2 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EWM21577.1 - 0.0021 18.0 0.1 0.0039 17.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ribosomal_S17e PF00833.13 EWM21578.1 - 1.6e-51 173.1 1.0 2.1e-51 172.7 0.7 1.2 1 0 0 1 1 1 1 Ribosomal S17 Amidohydro_2 PF04909.9 EWM21579.1 - 1.9e-27 96.5 3.6 9e-27 94.3 2.5 2.0 1 1 0 1 1 1 1 Amidohydrolase SMC_N PF02463.14 EWM21580.1 - 1.1e-66 224.1 0.0 1.7e-66 223.5 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EWM21580.1 - 1.1e-22 80.2 0.0 4.8e-22 78.1 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EWM21580.1 - 3.7e-11 43.5 0.0 1.4e-05 25.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EWM21580.1 - 1.2e-05 24.7 0.0 2.7e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 EWM21580.1 - 0.00027 20.1 5.7 0.092 11.7 0.0 3.2 4 0 0 4 4 4 2 AAA ATPase domain DUF4200 PF13863.1 EWM21580.1 - 0.0028 17.5 11.7 0.0028 17.5 8.1 9.3 4 4 4 9 9 9 1 Domain of unknown function (DUF4200) AAA_23 PF13476.1 EWM21580.1 - 0.044 14.1 82.7 4.3 7.5 35.5 6.7 3 2 1 4 4 4 0 AAA domain Reo_sigmaC PF04582.7 EWM21580.1 - 0.06 12.5 6.0 0.62 9.1 0.3 3.3 3 1 0 3 3 3 0 Reovirus sigma C capsid protein DUF87 PF01935.12 EWM21580.1 - 0.23 11.2 0.0 0.23 11.2 0.0 6.0 3 2 0 4 4 4 0 Domain of unknown function DUF87 ABC_tran PF00005.22 EWM21580.1 - 0.38 11.0 19.1 0.68 10.2 0.1 5.5 3 2 0 4 4 4 0 ABC transporter Peptidase_M28 PF04389.12 EWM21582.1 - 2.3e-19 69.8 0.0 4.1e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EWM21582.1 - 6e-06 25.8 0.1 1.4e-05 24.6 0.1 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 PA PF02225.17 EWM21582.1 - 0.00032 20.3 0.0 0.00099 18.7 0.0 1.8 1 0 0 1 1 1 1 PA domain SNARE PF05739.14 EWM21583.1 - 5.5e-05 22.7 0.6 8.8e-05 22.1 0.4 1.3 1 0 0 1 1 1 1 SNARE domain PAT1 PF09770.4 EWM21584.1 - 0.092 10.9 33.9 0.14 10.4 23.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF572 PF04502.8 EWM21584.1 - 1.5 8.0 24.6 2.1 7.4 17.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) MIP-T3 PF10243.4 EWM21584.1 - 4.1 5.7 42.9 7 4.9 29.7 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 WD40 PF00400.27 EWM21585.1 - 2.9e-31 106.1 1.6 1.4e-08 34.3 0.2 5.6 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ_2 PF13360.1 EWM21585.1 - 5.6e-06 25.9 1.9 0.038 13.4 0.3 2.6 2 1 0 2 2 2 2 PQQ-like domain LEA_2 PF03168.8 EWM21586.1 - 2.2e-09 37.5 0.0 3.8e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Late embryogenesis abundant protein OppC_N PF12911.2 EWM21586.1 - 0.04 13.2 0.3 0.07 12.5 0.2 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Ank_2 PF12796.2 EWM21587.1 - 2.3e-136 444.4 40.2 3.9e-23 81.6 0.2 10.3 2 1 7 11 11 11 10 Ankyrin repeats (3 copies) Ank PF00023.25 EWM21587.1 - 7.6e-116 372.6 37.3 1.6e-09 37.0 0.4 19.4 19 1 0 19 19 19 17 Ankyrin repeat Ank_4 PF13637.1 EWM21587.1 - 3.5e-87 285.4 8.9 5.7e-11 42.6 0.5 14.6 7 3 8 15 15 15 13 Ankyrin repeats (many copies) Ank_5 PF13857.1 EWM21587.1 - 1.3e-82 269.9 25.1 7.2e-11 41.9 0.1 15.4 6 3 11 17 17 17 15 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM21587.1 - 7.2e-70 223.9 18.8 5.4e-05 23.0 0.1 18.6 18 1 0 18 18 18 15 Ankyrin repeat Ricin_B_lectin PF00652.17 EWM21587.1 - 0.0064 16.5 0.2 0.014 15.3 0.2 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Shigella_OspC PF06128.6 EWM21587.1 - 0.37 10.2 13.2 3.1 7.2 0.1 5.3 5 2 1 6 6 6 0 Shigella flexneri OspC protein MatE PF01554.13 EWM21589.1 - 1.2e-20 73.7 25.9 2.3e-12 46.8 6.2 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 EWM21589.1 - 7.9e-10 38.7 6.3 7.9e-10 38.7 4.4 3.8 4 1 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Rad51 PF08423.6 EWM21591.1 - 3.5e-20 72.0 0.0 7.5e-20 70.9 0.0 1.5 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.1 EWM21591.1 - 1.9e-11 43.7 0.0 2.8e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EWM21591.1 - 1.9e-06 27.1 0.1 1.3e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 KaiC AAA_22 PF13401.1 EWM21591.1 - 0.00028 21.0 0.0 0.00049 20.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 EWM21591.1 - 0.0053 15.8 0.0 0.021 13.9 0.0 1.7 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_19 PF13245.1 EWM21591.1 - 0.022 14.4 0.0 0.079 12.7 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain DUF2075 PF09848.4 EWM21591.1 - 0.079 11.9 0.0 0.099 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 EWM21591.1 - 0.12 11.1 0.1 0.19 10.5 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain DUF819 PF05684.7 EWM21592.1 - 1.7e-26 92.9 22.0 2.9e-23 82.3 10.5 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF819) AMP-binding PF00501.23 EWM21593.1 - 1.4e-89 300.4 0.0 1.7e-89 300.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ABC2_membrane PF01061.19 EWM21595.1 - 9.6e-81 269.9 44.1 5.7e-41 139.9 7.6 3.1 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EWM21595.1 - 4.1e-52 176.1 0.4 1e-24 87.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 EWM21595.1 - 1.4e-21 76.9 46.4 9.2e-11 41.3 8.7 3.5 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.1 EWM21595.1 - 9.1e-14 52.0 0.7 0.016 15.2 0.2 4.6 4 1 0 4 4 4 3 AAA domain AAA_25 PF13481.1 EWM21595.1 - 5e-12 45.6 4.3 0.00021 20.7 0.3 3.8 4 0 0 4 4 4 2 AAA domain DUF258 PF03193.11 EWM21595.1 - 9.3e-09 34.6 2.2 0.00013 21.1 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SMC_N PF02463.14 EWM21595.1 - 4.6e-06 26.0 3.5 0.026 13.7 0.2 3.8 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EWM21595.1 - 4.8e-06 26.6 2.6 0.01 15.8 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EWM21595.1 - 9.9e-05 21.8 1.6 0.037 13.5 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EWM21595.1 - 0.00017 21.9 0.3 0.075 13.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EWM21595.1 - 0.00054 19.8 0.3 0.61 10.0 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 EWM21595.1 - 0.00093 19.1 0.9 0.79 9.6 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EWM21595.1 - 0.00097 19.2 1.1 1.1 9.3 0.1 2.8 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EWM21595.1 - 0.0013 18.7 2.9 0.29 11.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 EWM21595.1 - 0.0015 18.2 0.1 1.7 8.2 0.0 2.3 2 0 0 2 2 2 2 Archaeal ATPase NACHT PF05729.7 EWM21595.1 - 0.0016 18.1 2.5 0.52 9.9 0.1 2.6 2 0 0 2 2 2 2 NACHT domain AAA_17 PF13207.1 EWM21595.1 - 0.0023 18.7 2.0 1.2 9.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EWM21595.1 - 0.0025 17.9 0.2 3.1 8.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Miro PF08477.8 EWM21595.1 - 0.0029 18.0 0.6 2.6 8.5 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_18 PF13238.1 EWM21595.1 - 0.0064 16.7 1.0 4.6 7.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 EWM21595.1 - 0.019 14.0 0.0 2.1 7.2 0.0 3.4 4 0 0 4 4 4 0 AAA ATPase domain AAA PF00004.24 EWM21595.1 - 0.029 14.5 3.2 2.8 8.1 0.0 3.8 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 EWM21595.1 - 0.031 13.7 4.6 0.41 10.0 0.1 2.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 EWM21595.1 - 0.045 13.5 1.1 9.4 6.0 0.0 2.6 2 0 0 2 2 2 0 Dynamin family AAA_10 PF12846.2 EWM21595.1 - 0.061 12.7 5.2 0.72 9.2 0.5 2.4 2 0 0 2 2 2 0 AAA-like domain PduV-EutP PF10662.4 EWM21595.1 - 0.062 12.7 1.7 0.77 9.2 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 EWM21595.1 - 0.068 12.7 1.3 2.7 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EWM21595.1 - 0.072 12.5 2.0 4.9 6.5 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Adeno_IVa2 PF02456.10 EWM21595.1 - 0.13 10.8 0.1 4.8 5.7 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_14 PF13173.1 EWM21595.1 - 0.14 12.1 0.6 6.6 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 EWM21595.1 - 0.15 10.7 0.1 1.1 7.8 0.0 1.9 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein DUF87 PF01935.12 EWM21595.1 - 0.15 11.8 6.7 0.49 10.1 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 T2SE PF00437.15 EWM21595.1 - 0.47 9.3 4.3 1.1 8.1 0.0 2.7 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_5 PF07728.9 EWM21595.1 - 0.92 9.2 3.9 7.2 6.3 0.3 2.7 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) HypA PF01155.14 EWM21596.1 - 0.061 13.0 0.0 0.08 12.6 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Ank_2 PF12796.2 EWM21597.1 - 6.3e-45 151.4 11.4 8.1e-21 74.1 0.8 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EWM21597.1 - 2.9e-41 137.2 10.7 2.2e-07 30.3 0.1 7.5 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.1 EWM21597.1 - 4.6e-32 109.8 14.8 9.8e-09 35.5 0.1 6.2 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 EWM21597.1 - 1.2e-30 104.8 21.0 2.2e-10 40.4 0.0 6.3 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM21597.1 - 1.4e-23 80.5 3.1 0.0037 17.3 0.0 6.9 7 0 0 7 7 7 6 Ankyrin repeat LSM PF01423.17 EWM21598.1 - 8.6e-19 66.8 0.1 1.2e-18 66.4 0.1 1.2 1 0 0 1 1 1 1 LSM domain TRAM_LAG1_CLN8 PF03798.11 EWM21599.1 - 1.8e-36 125.5 24.3 1.8e-36 125.5 16.9 1.8 2 0 0 2 2 2 1 TLC domain Spo7 PF03907.8 EWM21599.1 - 0.19 11.3 4.8 0.064 12.8 0.4 2.0 2 0 0 2 2 2 0 Spo7-like protein Sedlin_N PF04628.8 EWM21600.1 - 2.3e-26 92.2 0.0 3e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EWM21600.1 - 0.0074 16.0 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Antimicrobial19 PF08225.6 EWM21600.1 - 0.03 13.7 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 Pseudin antimicrobial peptide zf-RING_4 PF14570.1 EWM21601.1 - 3.3e-18 64.9 18.9 6e-18 64.1 13.1 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 EWM21601.1 - 9e-06 25.2 0.0 1.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM21601.1 - 6e-05 22.9 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM21601.1 - 6.5e-05 22.6 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 EWM21601.1 - 0.0047 16.5 14.4 0.0085 15.7 10.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 EWM21601.1 - 0.38 10.5 9.0 0.37 10.5 4.4 2.2 2 0 0 2 2 2 0 Zinc-binding RING-finger MAGE_N PF12440.3 EWM21602.1 - 2.2 8.6 7.1 0.55 10.5 1.3 2.1 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal NCA2 PF08637.5 EWM21603.1 - 4e-33 114.5 0.0 5.8e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 TRAM_LAG1_CLN8 PF03798.11 EWM21604.1 - 0.00025 20.6 23.9 0.00025 20.6 16.5 1.7 2 0 0 2 2 2 1 TLC domain DUF2215 PF10225.4 EWM21606.1 - 2.9 7.2 4.0 0.53 9.6 0.3 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) Peptidase_M49 PF03571.10 EWM21607.1 - 2.6e-210 699.1 0.0 3e-210 698.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 Aminotran_5 PF00266.14 EWM21608.1 - 5.7e-31 107.5 0.0 2e-21 76.1 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Aminotran_1_2 PF00155.16 EWM21608.1 - 0.03 13.2 0.0 4.9 6.0 0.0 2.3 2 0 0 2 2 2 0 Aminotransferase class I and II C1_3 PF07649.7 EWM21608.1 - 0.075 13.0 1.0 4.3 7.4 0.1 2.5 2 0 0 2 2 2 0 C1-like domain TPR_11 PF13414.1 EWM21609.1 - 9.3e-11 41.2 2.3 0.00016 21.2 0.5 2.6 1 1 1 2 2 2 2 TPR repeat TPR_9 PF13371.1 EWM21609.1 - 0.0092 15.8 2.8 0.033 14.0 2.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat Calici_PP_N PF08405.6 EWM21609.1 - 0.015 14.1 1.3 0.027 13.3 0.9 1.3 1 0 0 1 1 1 0 Viral polyprotein N-terminal TPR_2 PF07719.12 EWM21609.1 - 0.099 12.6 1.0 23 5.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat CutC PF03932.9 EWM21610.1 - 1.8e-54 184.1 0.0 2.2e-54 183.8 0.0 1.1 1 0 0 1 1 1 1 CutC family PTE PF02126.13 EWM21610.1 - 0.13 11.2 0.1 0.2 10.6 0.1 1.2 1 0 0 1 1 1 0 Phosphotriesterase family BRO1 PF03097.13 EWM21611.1 - 2e-22 79.4 0.0 2.6e-22 79.0 0.0 1.0 1 0 0 1 1 1 1 BRO1-like domain UDP-g_GGTase PF06427.6 EWM21612.1 - 4.1e-32 111.1 0.0 9.9e-32 109.9 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 EWM21612.1 - 6.2e-06 25.7 0.1 1.1e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Lipase_3 PF01764.20 EWM21613.1 - 1.8e-09 37.3 0.0 3.2e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 EWM21613.1 - 0.00035 20.2 0.0 0.00062 19.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Esterase PF00756.15 EWM21613.1 - 0.0025 17.2 0.0 0.0059 16.0 0.0 1.6 1 1 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EWM21613.1 - 0.017 14.9 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EWM21613.1 - 0.023 14.5 0.0 0.064 13.1 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.9 EWM21613.1 - 0.074 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) RmlD_sub_bind PF04321.12 EWM21616.1 - 9.9e-14 50.8 0.0 7.9e-09 34.8 0.0 3.0 3 0 0 3 3 3 3 RmlD substrate binding domain Epimerase PF01370.16 EWM21616.1 - 0.00032 20.1 0.0 0.023 14.1 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EWM21617.1 - 9.6e-25 87.0 0.0 3.4e-20 72.1 0.0 3.1 3 0 0 3 3 3 2 RmlD substrate binding domain Epimerase PF01370.16 EWM21617.1 - 2.1e-19 69.8 0.0 9.2e-18 64.5 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EWM21617.1 - 3.5e-09 35.7 0.0 4.9e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EWM21617.1 - 6.1e-08 31.9 0.0 1.1e-05 24.5 0.0 2.1 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein adh_short PF00106.20 EWM21617.1 - 2.9e-06 27.3 0.0 5.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EWM21617.1 - 9.7e-05 21.4 0.0 0.00076 18.4 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 EWM21617.1 - 0.00054 19.6 0.0 0.00086 19.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.19 EWM21617.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain LSM PF01423.17 EWM21619.1 - 1.7e-17 62.7 1.4 2.1e-17 62.4 1.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EWM21619.1 - 0.0057 16.5 0.1 0.0076 16.1 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF3247 PF11607.3 EWM21619.1 - 0.092 12.9 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3247) Gemin7 PF11095.3 EWM21619.1 - 0.13 12.0 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) API5 PF05918.6 EWM21619.1 - 4.1 5.7 9.0 5 5.4 6.3 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) LSM PF01423.17 EWM21620.1 - 1.3e-18 66.2 1.4 1.7e-18 65.9 1.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EWM21620.1 - 0.0024 17.7 0.1 0.0028 17.5 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Gemin7 PF11095.3 EWM21620.1 - 0.0029 17.3 0.0 0.0038 16.9 0.0 1.2 1 0 0 1 1 1 1 Gem-associated protein 7 (Gemin7) DUF3247 PF11607.3 EWM21620.1 - 0.039 14.2 0.0 0.049 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3247) API5 PF05918.6 EWM21620.1 - 4.5 5.6 9.0 5.7 5.3 6.3 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) TFIIS_C PF01096.13 EWM21621.1 - 1.7e-16 59.5 3.9 3e-16 58.7 2.7 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) TFIIS_M PF07500.9 EWM21621.1 - 4.2e-14 52.5 0.0 8.5e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain Med26 PF08711.6 EWM21621.1 - 8.5e-06 25.1 0.0 1.8e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Baculo_LEF5_C PF11792.3 EWM21621.1 - 0.092 12.1 0.7 0.21 11.0 0.2 1.8 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain DUF3385 PF11865.3 EWM21622.1 - 0.00036 20.5 0.0 0.00049 20.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3385) Telomere_reg-2 PF10193.4 EWM21622.1 - 0.096 12.9 0.1 0.2 11.9 0.0 1.6 2 0 0 2 2 2 0 Telomere length regulation protein CH PF00307.26 EWM21623.1 - 1.7e-36 124.5 0.0 9.8e-19 67.3 0.0 2.5 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EWM21623.1 - 5.9e-08 32.2 0.0 2.1e-06 27.2 0.0 2.5 2 0 0 2 2 2 1 CAMSAP CH domain Spectrin PF00435.16 EWM21623.1 - 0.00086 19.5 10.0 0.024 14.9 0.1 5.0 4 1 2 6 6 6 2 Spectrin repeat LAGLIDADG_1 PF00961.14 EWM21623.1 - 0.038 14.5 0.2 2.2 8.8 0.0 2.5 2 0 0 2 2 2 0 LAGLIDADG endonuclease Ufm1 PF03671.9 EWM21624.1 - 2.9e-44 148.6 0.2 3.6e-44 148.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein Rad60-SLD PF11976.3 EWM21624.1 - 0.11 12.2 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like PARP_regulatory PF01358.13 EWM21625.1 - 1e-15 57.1 0.0 1.5e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Poly A polymerase regulatory subunit PI3_PI4_kinase PF00454.22 EWM21626.1 - 9.8e-41 139.7 0.0 1.7e-40 139.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EWM21626.1 - 6.9e-16 57.3 0.3 1.4e-15 56.4 0.2 1.6 1 0 0 1 1 1 1 FATC domain FAT PF02259.18 EWM21626.1 - 1.2e-14 54.0 0.0 2.1e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 FAT domain HEAT_EZ PF13513.1 EWM21626.1 - 0.0046 17.3 0.2 0.94 10.0 0.1 3.6 2 0 0 2 2 2 1 HEAT-like repeat COG4 PF08318.7 EWM21626.1 - 0.059 12.1 0.3 0.098 11.4 0.2 1.3 1 0 0 1 1 1 0 COG4 transport protein DUF4135 PF13575.1 EWM21626.1 - 0.14 11.1 0.0 0.56 9.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4135) Snf7 PF03357.16 EWM21627.1 - 1.4e-36 125.4 13.3 1.9e-36 125.0 9.2 1.1 1 0 0 1 1 1 1 Snf7 DUF939_C PF11728.3 EWM21627.1 - 0.084 12.6 8.2 0.18 11.6 5.7 1.6 1 1 0 1 1 1 0 DUF939 C-terminal domain PspA_IM30 PF04012.7 EWM21627.1 - 0.14 11.4 13.7 1.8 7.8 4.3 2.2 1 1 1 2 2 2 0 PspA/IM30 family YlqD PF11068.3 EWM21627.1 - 0.16 12.0 5.5 0.17 11.8 2.8 1.9 1 1 1 2 2 2 0 YlqD protein ATC_hydrolase PF14196.1 EWM21627.1 - 0.35 11.2 7.9 7.5 6.9 0.0 2.8 1 1 1 3 3 3 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase D5_N PF08706.6 EWM21627.1 - 5.8 6.9 6.6 3.9 7.5 3.1 1.7 1 1 1 2 2 2 0 D5 N terminal like Snf7 PF03357.16 EWM21628.1 - 1.3e-36 125.5 13.3 1.7e-36 125.1 9.2 1.1 1 0 0 1 1 1 1 Snf7 DUF939_C PF11728.3 EWM21628.1 - 0.069 12.9 8.0 0.14 11.9 5.6 1.6 1 1 0 1 1 1 0 DUF939 C-terminal domain PspA_IM30 PF04012.7 EWM21628.1 - 0.13 11.6 13.7 1.8 7.8 4.4 2.2 1 1 1 2 2 2 0 PspA/IM30 family YlqD PF11068.3 EWM21628.1 - 0.16 12.0 5.0 0.15 12.1 2.7 1.6 1 1 0 1 1 1 0 YlqD protein ATC_hydrolase PF14196.1 EWM21628.1 - 0.31 11.4 7.5 7.2 7.0 0.0 2.8 1 1 2 3 3 3 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase D5_N PF08706.6 EWM21628.1 - 6.2 6.9 6.2 4.8 7.2 3.0 1.7 1 1 0 2 2 2 0 D5 N terminal like Patatin PF01734.17 EWM21629.1 - 5.7e-09 36.2 1.1 3.6e-06 27.0 0.8 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase Ctf8 PF09696.5 EWM21630.1 - 4.7e-20 71.6 0.0 1.4e-19 70.0 0.0 1.7 1 1 0 1 1 1 1 Ctf8 Glucosamine_iso PF01182.15 EWM21631.1 - 4.6e-58 196.2 0.0 5.7e-58 195.9 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Thioredoxin PF00085.15 EWM21632.1 - 0.17 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin DNA_pol_B_thumb PF14791.1 EWM21633.1 - 1e-15 57.1 0.0 2e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.1 EWM21633.1 - 3.7e-07 30.2 0.0 2.5e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 EWM21633.1 - 5.6e-07 29.0 0.0 1.2e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.1 EWM21633.1 - 2.1e-05 24.5 0.0 4.1e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_5 PF14520.1 EWM21633.1 - 0.015 15.4 0.0 0.1 12.7 0.0 2.4 2 1 0 2 2 2 0 Helix-hairpin-helix domain BRCT PF00533.21 EWM21633.1 - 0.14 12.2 0.0 0.5 10.5 0.0 1.9 1 1 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain DNA_pol_B_thumb PF14791.1 EWM21634.1 - 7.8e-16 57.5 0.1 2e-15 56.2 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase beta thumb HHH_8 PF14716.1 EWM21634.1 - 3.7e-07 30.2 0.0 2.5e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 EWM21634.1 - 5.6e-07 29.0 0.0 1.2e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.1 EWM21634.1 - 2e-05 24.5 0.0 4.1e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_5 PF14520.1 EWM21634.1 - 0.015 15.4 0.0 0.1 12.8 0.0 2.4 2 1 0 2 2 2 0 Helix-hairpin-helix domain BRCT PF00533.21 EWM21634.1 - 0.14 12.3 0.0 0.5 10.5 0.0 1.9 1 1 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain FIBP PF05427.6 EWM21636.1 - 4.4e-43 147.8 0.0 2e-29 102.9 0.0 4.6 5 0 0 5 5 5 4 Acidic fibroblast growth factor binding (FIBP) Sulfotransfer_1 PF00685.22 EWM21638.1 - 1.3e-05 24.5 0.0 3.2e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 EWM21638.1 - 0.00011 23.1 0.6 0.00045 21.1 0.3 1.9 1 1 0 1 1 1 1 Sulfotransferase family Glycos_transf_4 PF00953.16 EWM21639.1 - 1.4e-34 119.2 9.4 1.4e-34 119.2 6.5 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 4 DUF2644 PF10841.3 EWM21639.1 - 0.017 15.1 0.3 0.072 13.1 0.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2644) S1FA PF04689.8 EWM21639.1 - 0.54 10.1 0.0 0.54 10.1 0.0 2.9 3 1 1 4 4 4 0 DNA binding protein S1FA Pex24p PF06398.6 EWM21641.1 - 4.4e-12 45.4 2.4 9.8e-12 44.3 1.7 1.6 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin cwf21 PF08312.7 EWM21643.1 - 6.6e-11 41.8 4.5 6.6e-11 41.8 3.1 2.6 3 0 0 3 3 3 1 cwf21 domain Ribosomal_L6e PF01159.14 EWM21645.1 - 3.8e-33 113.9 0.2 5.9e-33 113.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e FSIP1 PF15554.1 EWM21645.1 - 0.0032 16.3 0.2 0.0042 15.9 0.1 1.1 1 0 0 1 1 1 1 FSIP1 family DUF3199 PF11436.3 EWM21645.1 - 0.067 13.0 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3199) Ribosomal_L6e_N PF03868.10 EWM21645.1 - 2.4 8.0 6.8 0.16 11.9 0.6 2.0 2 0 0 2 2 2 0 Ribosomal protein L6, N-terminal domain RRM_1 PF00076.17 EWM21646.1 - 5.4e-23 80.4 0.4 1.5e-09 37.3 0.0 4.9 3 2 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM21646.1 - 1e-15 57.4 0.0 7e-06 25.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM21646.1 - 1.1e-09 37.9 0.0 0.00017 21.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HAD_2 PF13419.1 EWM21647.1 - 1.6e-20 74.0 0.0 2.5e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EWM21647.1 - 6.4e-08 32.1 0.0 1.2e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EWM21647.1 - 3.1e-07 31.0 0.0 4.9e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3441 PF11923.3 EWM21648.1 - 6e-28 96.7 0.0 1.2e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3441) DUF814 PF05670.8 EWM21648.1 - 3.1e-18 65.4 0.0 8.9e-18 63.9 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF814) FAD_binding_4 PF01565.18 EWM21649.1 - 2.8e-11 43.0 0.0 4.5e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Glyoxalase PF00903.20 EWM21649.1 - 0.046 13.7 0.0 4.2 7.3 0.0 2.5 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Pyr_redox PF00070.22 EWM21650.1 - 2e-16 60.1 0.7 1.7e-13 50.7 0.7 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EWM21650.1 - 1.3e-14 54.5 2.1 1.3e-08 34.9 0.0 3.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EWM21650.1 - 4.3e-07 29.8 0.3 0.032 14.2 0.1 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EWM21650.1 - 2.7e-06 26.5 11.9 0.015 14.1 0.8 4.1 3 1 0 4 4 4 3 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EWM21650.1 - 1e-05 25.3 0.4 0.22 11.2 0.1 3.4 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EWM21650.1 - 0.00017 21.6 0.0 0.0036 17.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EWM21650.1 - 0.00061 18.8 0.0 0.004 16.1 0.0 2.0 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 EWM21650.1 - 0.11 11.1 0.1 1.3 7.5 0.1 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Histone PF00125.19 EWM21651.1 - 3.2e-19 68.8 0.0 4.3e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.8 EWM21651.1 - 0.00081 19.6 0.0 0.0013 18.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TraH PF06122.6 EWM21651.1 - 0.0035 16.2 0.1 0.0036 16.1 0.1 1.0 1 0 0 1 1 1 1 Conjugative relaxosome accessory transposon protein CBFD_NFYB_HMF PF00808.18 EWM21651.1 - 0.025 14.6 0.0 0.056 13.4 0.0 1.6 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TPR_7 PF13176.1 EWM21652.1 - 0.092 12.5 0.2 0.69 9.8 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EWM21652.1 - 0.34 11.6 3.8 0.7 10.7 0.5 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat HEAT_2 PF13646.1 EWM21653.1 - 3.9e-11 43.0 7.2 0.00038 20.6 0.1 5.4 5 1 1 6 6 6 2 HEAT repeats HEAT PF02985.17 EWM21653.1 - 3.6e-10 39.0 15.6 0.016 15.2 0.0 8.4 10 0 0 10 10 10 2 HEAT repeat HEAT_EZ PF13513.1 EWM21653.1 - 0.00012 22.4 14.7 0.63 10.6 0.0 6.2 6 1 1 7 7 7 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EWM21653.1 - 0.00027 21.2 0.0 1.9 8.9 0.0 4.6 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EWM21653.1 - 0.0049 16.7 9.1 0.091 12.6 0.1 5.1 6 0 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 DUF2454 PF10521.4 EWM21653.1 - 0.034 13.1 0.8 0.59 9.0 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2454) CLASP_N PF12348.3 EWM21653.1 - 0.044 13.1 3.3 2.9 7.1 0.1 4.1 3 2 0 3 3 3 0 CLASP N terminal tRNA-synt_2 PF00152.15 EWM21654.1 - 5.8e-11 41.7 0.0 6.4e-11 41.6 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Cut8_M PF14483.1 EWM21654.1 - 0.01 15.6 0.2 0.51 10.1 0.0 2.8 3 0 0 3 3 3 0 Cut8 dimerisation domain Glycos_transf_2 PF00535.21 EWM21655.1 - 5e-15 55.5 0.0 8.9e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EWM21655.1 - 2.8e-08 33.8 0.1 6.2e-08 32.7 0.1 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EWM21655.1 - 9.4e-05 21.6 0.0 0.0021 17.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 tRNA-synt_2 PF00152.15 EWM21656.1 - 3.1e-15 55.8 0.0 3.6e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) GST_C_3 PF14497.1 EWM21656.1 - 7.4e-07 29.5 0.0 1.7e-06 28.3 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EWM21656.1 - 0.026 14.3 0.0 0.059 13.2 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain LRR_6 PF13516.1 EWM21657.1 - 0.19 11.9 2.6 0.77 10.0 0.1 2.7 3 0 0 3 3 3 0 Leucine Rich repeat LRR_7 PF13504.1 EWM21657.1 - 1.1 9.7 3.8 11 6.6 0.1 3.3 3 0 0 3 3 3 0 Leucine rich repeat CDC45 PF02724.9 EWM21657.1 - 5.4 4.9 16.2 6.8 4.6 11.2 1.1 1 0 0 1 1 1 0 CDC45-like protein CENP-T PF15511.1 EWM21657.1 - 5.7 6.0 19.5 7.6 5.6 13.5 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF605 PF04652.11 EWM21657.1 - 7.3 5.8 11.4 9.9 5.4 7.9 1.1 1 0 0 1 1 1 0 Vta1 like fn3 PF00041.16 EWM21658.1 - 5.7e-09 35.9 0.0 1.3e-08 34.7 0.0 1.6 1 1 0 1 1 1 1 Fibronectin type III domain CENP-T PF15511.1 EWM21658.1 - 2 7.5 8.4 2.5 7.2 5.8 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Trypsin_2 PF13365.1 EWM21659.1 - 7.8e-23 80.7 0.1 1.4e-22 79.8 0.1 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 EWM21659.1 - 1.3e-17 64.1 0.0 1.8e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Trypsin Peptidase_S32 PF05579.8 EWM21659.1 - 0.0029 16.6 0.5 0.26 10.2 0.0 2.2 2 0 0 2 2 2 2 Equine arteritis virus serine endopeptidase S32 Peptidase_S29 PF02907.10 EWM21659.1 - 0.0069 15.9 0.1 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 Hepatitis C virus NS3 protease Peptidase_S46 PF10459.4 EWM21659.1 - 0.012 14.0 0.5 0.23 9.8 0.2 2.0 2 0 0 2 2 2 0 Peptidase S46 L_protein_N PF15518.1 EWM21659.1 - 0.19 11.1 0.0 0.28 10.5 0.0 1.1 1 0 0 1 1 1 0 L protein N-terminus DUF605 PF04652.11 EWM21660.1 - 0.084 12.2 24.5 0.23 10.7 6.0 2.3 2 0 0 2 2 2 0 Vta1 like Ank_2 PF12796.2 EWM21661.1 - 3.2e-67 222.9 5.0 6.4e-17 61.6 0.0 4.7 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EWM21661.1 - 6.5e-50 164.5 8.6 4.3e-07 29.4 0.3 8.6 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.1 EWM21661.1 - 2e-36 123.1 4.1 7.8e-08 32.3 0.2 6.4 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EWM21661.1 - 3e-34 116.7 2.3 2.6e-08 34.1 0.1 6.4 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM21661.1 - 4.1e-31 103.9 1.8 0.0012 18.9 0.2 8.5 8 0 0 8 8 8 6 Ankyrin repeat fn3 PF00041.16 EWM21661.1 - 0.021 14.9 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 Fibronectin type III domain DUF2360 PF10152.4 EWM21661.1 - 3.8 7.7 5.2 0.83 9.9 0.3 2.0 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) FHA PF00498.21 EWM21662.1 - 4.5e-16 58.7 0.0 7.2e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 FHA domain Beta-lactamase PF00144.19 EWM21663.1 - 3.5e-22 78.8 0.0 4.7e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Clat_adaptor_s PF01217.15 EWM21665.1 - 1.6e-56 189.9 2.1 1.9e-56 189.6 1.5 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain GPI-anchored PF10342.4 EWM21666.1 - 0.11 13.0 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Ribosomal_60s PF00428.14 EWM21668.1 - 1.5e-11 44.5 10.2 2e-11 44.1 7.1 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein SR-25 PF10500.4 EWM21670.1 - 3.4 7.0 9.7 5.5 6.4 6.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Tim17 PF02466.14 EWM21671.1 - 3.4e-08 33.5 11.0 4e-08 33.3 7.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_YMGG PF13441.1 EWM21671.1 - 0.0049 16.3 16.1 0.011 15.2 1.6 2.7 2 1 0 2 2 2 2 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.1 EWM21671.1 - 0.0082 15.7 11.6 0.03 13.9 0.1 2.4 2 1 0 2 2 2 2 Glycine-zipper containing OmpA-like membrane domain Romo1 PF10247.4 EWM21671.1 - 0.03 14.5 0.5 0.03 14.5 0.3 2.4 1 1 2 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 Gly-zipper_Omp PF13488.1 EWM21671.1 - 0.044 13.4 0.7 0.044 13.4 0.5 3.0 3 1 1 4 4 4 0 Glycine zipper DUF1269 PF06897.7 EWM21671.1 - 0.2 11.6 4.4 0.45 10.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) TraT PF05818.7 EWM21671.1 - 0.34 10.2 5.8 5.1 6.4 1.0 2.1 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein Bacteriocin_IIc PF10439.4 EWM21671.1 - 9.3 6.4 21.5 0.98 9.5 0.7 2.9 2 1 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Tim17 PF02466.14 EWM21672.1 - 3.7e-07 30.2 10.1 4.3e-07 30.0 7.0 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_OmpA PF13436.1 EWM21672.1 - 0.48 10.0 11.0 3.3 7.4 0.1 2.4 2 1 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Romo1 PF10247.4 EWM21672.1 - 0.76 10.0 7.2 1.1 9.5 0.2 2.4 1 1 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Gly-zipper_Omp PF13488.1 EWM21672.1 - 3.1 7.5 18.2 2.1 8.0 0.5 3.1 3 1 0 3 3 3 0 Glycine zipper Gly-zipper_YMGG PF13441.1 EWM21672.1 - 3.4 7.2 19.0 5.4 6.6 4.3 2.8 2 1 0 2 2 2 0 YMGG-like Gly-zipper FYVE PF01363.16 EWM21674.1 - 2e-14 53.2 6.4 2e-14 53.2 4.4 2.2 2 0 0 2 2 2 1 FYVE zinc finger Ribosomal_L3 PF00297.17 EWM21675.1 - 1e-38 133.2 0.7 1.3e-38 132.9 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 Cytochrom_B562 PF07361.6 EWM21675.1 - 0.045 14.1 0.1 0.19 12.1 0.0 1.9 2 0 0 2 2 2 0 Cytochrome b562 FadA PF09403.5 EWM21675.1 - 0.11 12.5 0.6 0.17 11.8 0.4 1.3 1 0 0 1 1 1 0 Adhesion protein FadA MRP-S33 PF08293.6 EWM21675.1 - 0.12 12.3 2.1 0.17 11.8 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit S27 RNase_T PF00929.19 EWM21677.1 - 6.5e-14 52.5 0.0 7.7e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Exonuclease MFS_1 PF07690.11 EWM21678.1 - 9.6e-23 80.4 16.8 1.3e-22 80.0 11.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EWM21678.1 - 0.00068 19.3 0.7 0.0019 17.9 0.2 1.9 2 0 0 2 2 2 1 MFS_1 like family Sugar_tr PF00083.19 EWM21678.1 - 0.001 17.7 11.9 0.0046 15.5 8.1 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 EWM21678.1 - 0.0012 17.3 1.6 0.0012 17.3 1.1 1.7 2 0 0 2 2 2 1 MFS/sugar transport protein LacY_symp PF01306.14 EWM21678.1 - 0.72 8.3 13.1 2.7 6.4 8.9 1.8 1 1 0 1 1 1 0 LacY proton/sugar symporter Myb_DNA-binding PF00249.26 EWM21680.1 - 1.3e-27 95.5 5.8 9.5e-14 51.1 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EWM21680.1 - 1.7e-22 79.2 2.7 4.5e-14 52.2 0.2 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EWM21680.1 - 3.6 7.7 6.7 33 4.7 1.1 3.0 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Sec23_helical PF04815.10 EWM21682.1 - 7.2e-21 73.5 0.2 6.2e-20 70.5 0.0 2.4 2 1 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EWM21682.1 - 1.1e-11 45.0 0.0 2.1e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 EWM21682.1 - 0.0035 17.0 0.0 0.0066 16.1 0.0 1.4 1 0 0 1 1 1 1 Gelsolin repeat GCS PF03074.11 EWM21683.1 - 4e-32 111.6 0.0 2.1e-27 96.1 0.0 2.1 1 1 1 2 2 2 2 Glutamate-cysteine ligase DUF1479 PF07350.7 EWM21683.1 - 0.12 10.8 0.0 0.19 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) Umbravirus_LDM PF04817.7 EWM21684.1 - 0.1 11.7 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Umbravirus long distance movement (LDM) family TPR_11 PF13414.1 EWM21687.1 - 0.024 14.2 0.9 0.38 10.4 0.2 2.3 2 0 0 2 2 2 0 TPR repeat Apc5 PF12862.2 EWM21687.1 - 0.13 12.1 0.3 1 9.2 0.2 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 5 TPR_2 PF07719.12 EWM21687.1 - 0.15 12.0 2.9 0.16 11.9 0.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EWM21687.1 - 0.66 10.5 3.6 0.77 10.3 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat CRCB PF02537.10 EWM21691.1 - 2.9e-11 43.2 0.6 4e-11 42.8 0.4 1.1 1 0 0 1 1 1 1 CrcB-like protein Asp PF00026.18 EWM21692.1 - 0.013 14.8 0.0 0.013 14.8 0.0 2.7 3 0 0 3 3 3 0 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EWM21692.1 - 0.018 15.5 0.0 0.73 10.3 0.0 2.5 2 0 0 2 2 2 0 Aspartyl protease DUF4614 PF15391.1 EWM21692.1 - 0.025 14.3 5.9 0.039 13.7 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Phosphoprotein PF00922.12 EWM21692.1 - 0.1 11.8 5.0 0.14 11.3 3.5 1.2 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein Mito_carr PF00153.22 EWM21694.1 - 5.5e-46 154.2 0.7 1.1e-20 73.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PhyH PF05721.8 EWM21695.1 - 7.3e-21 75.1 0.1 1.6e-20 74.0 0.0 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.1 EWM21695.1 - 0.0082 16.6 0.0 0.014 15.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2237 PF09996.4 EWM21702.1 - 5.8e-54 180.5 0.1 8.6e-54 180.0 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) DUF4137 PF13593.1 EWM21704.1 - 1.5e-34 119.5 12.6 2.4e-34 118.8 8.8 1.2 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.11 EWM21704.1 - 2.5e-05 23.7 8.7 4.4e-05 22.9 6.0 1.4 1 0 0 1 1 1 1 Sodium Bile acid symporter family LRR_6 PF13516.1 EWM21709.1 - 0.0044 16.9 0.1 7.6 6.9 0.0 3.1 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.28 EWM21709.1 - 0.042 13.8 1.3 4.2 7.7 0.0 3.5 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_4 PF12799.2 EWM21709.1 - 0.11 12.1 0.1 0.68 9.6 0.0 2.5 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EWM21709.1 - 0.64 10.4 3.3 66 4.3 0.0 4.0 4 1 0 4 4 4 0 Leucine rich repeat PI3_PI4_kinase PF00454.22 EWM21711.1 - 2.7e-32 112.1 0.0 3.8e-25 88.7 0.0 2.3 2 0 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EWM21711.1 - 2.8e-10 39.4 0.0 7.1e-10 38.1 0.0 1.8 1 0 0 1 1 1 1 FATC domain FMO-like PF00743.14 EWM21711.1 - 4.4 5.3 0.1 6.7 4.7 0.1 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Na_H_Exchanger PF00999.16 EWM21712.1 - 4.6e-21 74.7 11.2 6.6e-21 74.2 7.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Asp-Al_Ex PF06826.7 EWM21712.1 - 0.29 10.6 7.8 0.031 13.7 2.0 1.9 2 1 1 3 3 3 0 Predicted Permease Membrane Region Lipase_GDSL_2 PF13472.1 EWM21715.1 - 4.1e-24 85.6 0.1 5.3e-24 85.3 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EWM21715.1 - 2.4e-22 79.9 0.0 3.3e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Chalcone PF02431.10 EWM21716.1 - 2e-15 56.7 0.0 8.7e-15 54.6 0.0 1.9 1 1 0 1 1 1 1 Chalcone-flavanone isomerase Endonuclease_NS PF01223.18 EWM21716.1 - 0.077 12.6 0.5 0.16 11.5 0.3 1.5 1 0 0 1 1 1 0 DNA/RNA non-specific endonuclease PAT1 PF09770.4 EWM21716.1 - 0.23 9.6 17.6 0.32 9.1 12.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hexapep PF00132.19 EWM21719.1 - 9.6e-08 31.2 6.3 0.0024 17.3 0.3 4.0 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 EWM21719.1 - 5.2e-07 29.2 0.0 9.1e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EWM21719.1 - 0.0058 16.7 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 MobA-like NTP transferase domain W2 PF02020.13 EWM21719.1 - 0.014 15.3 0.5 0.014 15.3 0.4 1.9 2 0 0 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon Fucokinase PF07959.7 EWM21719.1 - 0.11 11.0 1.4 0.21 10.1 1.0 1.3 1 0 0 1 1 1 0 L-fucokinase BNR_3 PF13859.1 EWM21720.1 - 0.0016 17.5 6.7 0.14 11.1 0.5 2.0 1 1 1 2 2 2 2 BNR repeat-like domain SnoaL_3 PF13474.1 EWM21720.1 - 0.04 13.9 0.6 0.48 10.4 0.1 2.0 1 1 1 2 2 2 0 SnoaL-like domain PSII_BNR PF14870.1 EWM21720.1 - 0.064 12.2 5.7 0.11 11.4 4.0 1.4 1 1 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 BNR PF02012.15 EWM21720.1 - 0.079 12.8 0.4 0.079 12.8 0.3 3.6 5 0 0 5 5 5 0 BNR/Asp-box repeat SKG6 PF08693.5 EWM21720.1 - 6.4 6.1 5.6 15 5.0 0.1 2.7 3 0 0 3 3 3 0 Transmembrane alpha-helix domain UCH PF00443.24 EWM21721.1 - 4.7e-08 32.4 0.0 1e-07 31.3 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EWM21721.1 - 1.8e-07 31.1 1.3 3.8e-07 30.1 0.9 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein DZR PF12773.2 EWM21721.1 - 0.17 11.7 4.2 1.5 8.7 2.0 2.7 2 1 0 2 2 2 0 Double zinc ribbon zf-RING_4 PF14570.1 EWM21721.1 - 0.67 9.5 5.9 0.42 10.2 0.3 2.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Hep_core_N PF08290.6 EWM21722.1 - 0.078 12.4 0.1 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Hepatitis core protein, putative zinc finger Trypsin PF00089.21 EWM21724.1 - 2.1e-51 174.6 0.1 5.5e-51 173.2 0.1 1.7 1 1 0 1 1 1 1 Trypsin DUF482 PF04339.7 EWM21724.1 - 0.068 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF482 DUF316 PF03761.10 EWM21724.1 - 0.088 12.1 0.0 3.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF316) Rab3-GTPase_cat PF13890.1 EWM21725.1 - 1.7e-21 76.3 0.0 8e-21 74.1 0.0 2.1 2 0 0 2 2 2 1 Rab3 GTPase-activating protein catalytic subunit MIP-T3 PF10243.4 EWM21725.1 - 1 7.7 14.4 1.7 7.0 10.0 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DEAD PF00270.24 EWM21727.1 - 1.3e-11 44.2 0.0 1.5e-11 44.1 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EWM21727.1 - 0.00035 20.4 0.0 0.00035 20.4 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit eIF3_subunit PF08597.5 EWM21729.1 - 0.071 12.6 2.6 0.085 12.3 1.8 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Sm_multidrug_ex PF06695.6 EWM21730.1 - 8.5e-11 42.0 2.1 1.4e-06 28.4 0.1 2.8 3 0 0 3 3 3 2 Putative small multi-drug export protein Tim17 PF02466.14 EWM21731.1 - 3.3e-05 23.9 8.9 6.4e-05 23.0 6.2 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF3357 PF11837.3 EWM21731.1 - 0.0057 16.4 0.4 0.013 15.3 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3357) Transketolase_C PF02780.15 EWM21732.1 - 5.7e-34 116.7 0.0 1.1e-33 115.8 0.0 1.4 2 0 0 2 2 2 1 Transketolase, C-terminal domain Transket_pyr PF02779.19 EWM21732.1 - 9.6e-17 61.0 0.1 1.5e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Hist_deacetyl PF00850.14 EWM21734.1 - 1.5e-76 257.6 0.1 3.5e-76 256.4 0.0 1.5 2 0 0 2 2 2 1 Histone deacetylase domain ThiF PF00899.16 EWM21735.1 - 1.1e-32 112.7 0.0 1.7e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EWM21735.1 - 0.0049 16.4 0.0 0.019 14.5 0.0 2.0 1 0 0 1 1 1 1 MoeZ/MoeB domain FAD_binding_3 PF01494.14 EWM21735.1 - 0.047 12.7 0.9 0.071 12.1 0.6 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.1 EWM21735.1 - 0.06 13.6 0.0 0.13 12.4 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 EWM21735.1 - 0.11 11.6 0.0 0.29 10.2 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Peptidase_C1 PF00112.18 EWM21736.1 - 1.5e-61 208.0 1.4 2e-61 207.6 1.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EWM21736.1 - 3.4e-12 46.4 0.0 5.4e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) E1_DerP2_DerF2 PF02221.10 EWM21736.1 - 4.4e-10 39.9 0.0 1.2e-09 38.5 0.0 1.7 2 0 0 2 2 2 1 ML domain Peptidase_C1_2 PF03051.10 EWM21736.1 - 0.0021 16.6 0.7 0.0082 14.7 0.3 1.9 2 0 0 2 2 2 1 Peptidase C1-like family GTP1_OBG PF01018.17 EWM21738.1 - 3.7e-35 120.8 11.9 2.2e-33 115.1 6.1 2.2 2 0 0 2 2 2 2 GTP1/OBG Thioredoxin PF00085.15 EWM21739.1 - 3e-19 68.6 0.0 4.2e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EWM21739.1 - 4e-05 23.6 0.0 0.00027 20.9 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_6 PF13848.1 EWM21739.1 - 0.00042 20.1 0.0 0.00054 19.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EWM21739.1 - 0.00071 19.7 0.1 0.0045 17.1 0.0 2.2 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EWM21739.1 - 0.012 15.6 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like TPR_19 PF14559.1 EWM21739.1 - 0.013 15.8 0.2 0.036 14.4 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Thioredoxin PF00085.15 EWM21740.1 - 3e-19 68.6 0.0 4.2e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EWM21740.1 - 4e-05 23.6 0.0 0.00027 20.9 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_6 PF13848.1 EWM21740.1 - 0.00042 20.1 0.0 0.00054 19.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EWM21740.1 - 0.00071 19.7 0.1 0.0045 17.1 0.0 2.2 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EWM21740.1 - 0.012 15.6 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like TPR_19 PF14559.1 EWM21740.1 - 0.013 15.8 0.2 0.036 14.4 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat GerE PF00196.14 EWM21742.1 - 8.2e-10 37.8 0.0 1.3e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory proteins, luxR family HTH_23 PF13384.1 EWM21742.1 - 0.12 12.0 0.0 0.36 10.5 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain DHHA1 PF02272.14 EWM21746.1 - 0.083 12.6 0.1 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 DHHA1 domain KOW PF00467.24 EWM21749.1 - 0.0005 19.6 6.1 0.0012 18.4 4.2 1.6 1 0 0 1 1 1 1 KOW motif ARD PF03079.9 EWM21750.1 - 4.4e-57 192.4 0.4 5.3e-57 192.1 0.3 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EWM21750.1 - 2e-08 33.5 0.0 5e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EWM21750.1 - 3e-06 26.9 0.0 4.3e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EWM21750.1 - 0.0062 15.9 0.0 0.019 14.4 0.0 1.7 2 0 0 2 2 2 1 Cupin Cytochrom_B_N PF00033.14 EWM21751.1 - 1.1e-13 51.0 5.0 1.4e-13 50.6 3.5 1.1 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Ni_hydr_CYTB PF01292.15 EWM21751.1 - 1.4e-11 44.1 3.9 1.9e-11 43.6 2.7 1.2 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 FMO-like PF00743.14 EWM21751.1 - 0.027 12.6 0.0 0.036 12.2 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like DUF4405 PF14358.1 EWM21751.1 - 0.22 11.7 2.6 2.3 8.4 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) ACPS PF01648.15 EWM21752.1 - 1.2e-12 47.6 0.0 3.8e-12 46.0 0.0 1.9 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily DUF645 PF04875.7 EWM21753.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF645 Ribosomal_L39 PF00832.15 EWM21753.1 - 2 7.9 4.7 4.5 6.8 3.2 1.7 1 1 0 1 1 1 0 Ribosomal L39 protein PEX-1N PF09262.6 EWM21754.1 - 3.1e-22 78.4 0.3 5.4e-22 77.6 0.2 1.4 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal PNK3P PF08645.6 EWM21756.1 - 1.1e-44 151.7 0.0 1.4e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase HAD_2 PF13419.1 EWM21756.1 - 1.7e-05 25.1 0.0 0.00029 21.1 0.0 2.3 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase ADH_zinc_N PF00107.21 EWM21757.1 - 3.2e-22 78.4 0.1 6e-22 77.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EWM21757.1 - 4.3e-08 34.1 0.0 1.2e-07 32.6 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CS PF04969.11 EWM21757.1 - 1.8e-06 28.3 0.0 3e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 CS domain Siah-Interact_N PF09032.6 EWM21757.1 - 0.21 11.6 0.0 0.71 9.9 0.0 1.9 2 0 0 2 2 2 0 Siah interacting protein, N terminal PDZ_2 PF13180.1 EWM21758.1 - 1.1e-05 25.2 0.0 2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 EWM21758.1 - 1.1e-05 25.4 0.1 2.1e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) MYCBPAP PF14646.1 EWM21758.1 - 0.0057 15.4 0.1 0.0078 14.9 0.1 1.2 1 0 0 1 1 1 1 MYCBP-associated protein family TraC PF07820.7 EWM21758.1 - 0.0069 16.5 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 TraC-like protein AAA PF00004.24 EWM21759.1 - 2.9e-41 140.7 0.0 6.2e-41 139.6 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EWM21759.1 - 6.9e-06 26.1 0.1 4.1e-05 23.6 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EWM21759.1 - 0.00021 21.4 0.0 0.019 15.1 0.0 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EWM21759.1 - 0.00031 19.8 0.0 0.00061 18.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EWM21759.1 - 0.0012 19.6 0.0 0.0024 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EWM21759.1 - 0.0019 17.6 0.2 0.57 9.5 0.1 2.4 1 1 1 2 2 2 2 AAA domain TIP49 PF06068.8 EWM21759.1 - 0.0055 15.4 0.0 0.0083 14.8 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EWM21759.1 - 0.0083 16.0 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EWM21759.1 - 0.0098 15.6 2.7 0.017 14.8 0.1 2.9 3 0 0 3 3 3 1 Part of AAA domain Zeta_toxin PF06414.7 EWM21759.1 - 0.021 13.8 0.0 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.9 EWM21759.1 - 0.024 14.3 0.1 0.057 13.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EWM21759.1 - 0.038 13.9 0.0 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 EWM21759.1 - 0.049 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EWM21759.1 - 0.055 12.8 0.2 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 EWM21759.1 - 0.066 12.3 0.2 0.16 11.1 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EWM21759.1 - 0.084 12.5 0.3 0.73 9.4 0.1 2.4 3 0 0 3 3 3 0 NACHT domain Rad17 PF03215.10 EWM21759.1 - 0.17 10.4 0.0 0.24 10.0 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 EWM21759.1 - 0.18 12.0 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase TB2_DP1_HVA22 PF03134.14 EWM21760.1 - 1.4e-15 56.8 0.3 2e-15 56.2 0.2 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Pkinase PF00069.20 EWM21761.1 - 6.6e-76 254.8 0.0 6.6e-76 254.8 0.0 3.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM21761.1 - 1.5e-39 135.6 0.0 1.5e-39 135.6 0.0 3.4 3 1 0 3 3 3 1 Protein tyrosine kinase KA1 PF02149.14 EWM21761.1 - 9.3e-08 31.3 0.0 1.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 CDC45 PF02724.9 EWM21761.1 - 2.2 6.2 43.1 3.2 5.6 29.9 1.3 1 0 0 1 1 1 0 CDC45-like protein MFS_1 PF07690.11 EWM21762.1 - 0.043 12.5 0.4 0.05 12.3 0.3 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF843 PF05814.6 EWM21762.1 - 0.15 11.8 0.3 6.1 6.7 0.5 2.1 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) MFS_1 PF07690.11 EWM21763.1 - 0.037 12.7 0.4 0.043 12.5 0.3 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF843 PF05814.6 EWM21763.1 - 0.13 12.0 0.3 5.6 6.8 0.5 2.1 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) FixQ PF05545.6 EWM21763.1 - 1.2 8.8 0.0 1.2 8.8 0.0 2.0 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ MFS_1 PF07690.11 EWM21764.1 - 0.037 12.7 0.4 0.043 12.5 0.3 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF843 PF05814.6 EWM21764.1 - 0.13 12.0 0.3 5.6 6.8 0.5 2.1 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) FixQ PF05545.6 EWM21764.1 - 1.2 8.8 0.0 1.2 8.8 0.0 2.0 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF1295 PF06966.7 EWM21765.1 - 1.1e-36 126.2 17.9 1.9e-35 122.2 12.4 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Cpn60_TCP1 PF00118.19 EWM21766.1 - 3.5e-136 454.6 7.2 2.4e-135 451.9 5.0 1.9 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.19 EWM21767.1 - 1.2e-86 291.3 1.2 9.6e-86 288.3 0.8 1.9 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family TRAM_LAG1_CLN8 PF03798.11 EWM21768.1 - 5.4e-07 29.3 17.4 5.4e-07 29.3 12.0 2.2 1 1 1 2 2 2 1 TLC domain Spc97_Spc98 PF04130.8 EWM21770.1 - 2.7e-08 32.6 0.0 6.4e-08 31.3 0.0 1.6 1 1 0 1 1 1 1 Spc97 / Spc98 family IATP PF04568.7 EWM21770.1 - 0.2 11.6 1.3 0.54 10.3 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP DUF2203 PF09969.4 EWM21771.1 - 0.0019 18.3 0.3 0.0076 16.4 0.2 1.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2203) MatE PF01554.13 EWM21773.1 - 4e-14 52.5 2.8 4e-14 52.5 2.0 4.1 3 2 1 4 4 4 2 MatE Polysacc_synt_C PF14667.1 EWM21773.1 - 1.5e-09 37.8 5.3 1.5e-09 37.8 3.7 3.3 2 1 2 4 4 4 1 Polysaccharide biosynthesis C-terminal domain TisB_toxin PF13939.1 EWM21774.1 - 0.037 13.7 3.9 0.067 12.9 2.7 1.4 1 0 0 1 1 1 0 Toxin TisB, type I toxin-antitoxin system Tetraspannin PF00335.15 EWM21774.1 - 1.7 7.8 14.9 0.038 13.2 1.5 2.2 2 0 0 2 2 2 0 Tetraspanin family Ion_trans PF00520.26 EWM21776.1 - 1.2e-28 99.7 33.4 5.4e-17 61.7 7.2 2.4 2 0 0 2 2 2 2 Ion transport protein Neur_chan_memb PF02932.11 EWM21776.1 - 0.16 11.8 0.2 17 5.2 0.0 2.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF179 PF02622.10 EWM21777.1 - 1.5e-09 37.7 0.0 2.3e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 DIX PF00778.12 EWM21779.1 - 7e-06 25.6 0.0 9.5e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 DIX domain DUF966 PF06136.8 EWM21779.1 - 0.089 12.1 0.9 1 8.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF966) WAP PF00095.16 EWM21780.1 - 0.25 11.3 10.7 0.71 9.8 7.4 1.8 1 1 0 1 1 1 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' CDO_I PF05995.7 EWM21781.1 - 7e-27 93.7 0.0 1.3e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 EWM21781.1 - 0.01 15.2 0.0 0.031 13.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1637) Phosducin PF02114.11 EWM21782.1 - 8.1e-20 70.6 0.0 3.4e-19 68.5 0.0 1.8 1 1 0 1 1 1 1 Phosducin Lipase_GDSL_2 PF13472.1 EWM21783.1 - 0.0015 18.6 0.0 0.0027 17.8 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EWM21783.1 - 0.075 12.8 0.0 0.13 12.0 0.0 1.5 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase DUF3595 PF12166.3 EWM21785.1 - 1e-75 255.2 0.0 2.9e-75 253.6 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3595) F-box PF00646.28 EWM21786.1 - 5.1e-07 29.1 0.2 1.2e-06 27.9 0.2 1.7 1 0 0 1 1 1 1 F-box domain ZZ PF00569.12 EWM21786.1 - 3.3e-06 26.5 11.2 8e-06 25.3 7.7 1.6 1 0 0 1 1 1 1 Zinc finger, ZZ type F-box-like PF12937.2 EWM21786.1 - 2.1e-05 24.1 1.3 5e-05 22.9 0.9 1.6 1 0 0 1 1 1 1 F-box-like Aminotran_1_2 PF00155.16 EWM21787.1 - 2.1e-47 161.8 0.0 2.7e-47 161.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EWM21787.1 - 1.8e-08 33.9 0.1 2.7e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EWM21787.1 - 0.00026 20.1 0.0 0.00041 19.4 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family OKR_DC_1 PF01276.15 EWM21787.1 - 0.0081 14.7 0.0 0.022 13.3 0.0 1.6 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.15 EWM21787.1 - 0.031 12.5 0.0 0.048 11.9 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF3498 PF12004.3 EWM21787.1 - 0.22 10.6 8.9 0.31 10.1 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) Pol_alpha_B_N PF08418.5 EWM21787.1 - 9.2 5.7 10.7 15 5.0 7.4 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF605 PF04652.11 EWM21787.1 - 9.6 5.4 10.8 14 4.9 7.5 1.1 1 0 0 1 1 1 0 Vta1 like Dynactin_p62 PF05502.8 EWM21790.1 - 5.9e-19 68.2 1.5 5.9e-19 68.2 1.0 2.4 2 1 1 3 3 3 2 Dynactin p62 family Elf1 PF05129.8 EWM21790.1 - 0.21 11.2 2.9 0.14 11.8 0.5 1.9 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like HSP70 PF00012.15 EWM21791.1 - 2.3e-103 346.1 0.0 2.5e-85 286.6 0.0 2.2 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 EWM21791.1 - 3.3e-15 55.5 0.9 8.2e-11 41.0 0.0 3.1 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.11 EWM21791.1 - 2e-05 24.3 0.3 4.6e-05 23.1 0.1 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.6 EWM21791.1 - 0.41 9.5 0.0 0.68 8.8 0.0 1.2 1 0 0 1 1 1 0 StbA protein UDPGP PF01704.13 EWM21792.1 - 1.3e-89 300.6 0.0 1.8e-89 300.2 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PGM_PMM_I PF02878.11 EWM21792.1 - 1.5e-28 99.0 0.0 2.7e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EWM21792.1 - 1.4e-23 83.1 0.0 2.7e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EWM21792.1 - 7.1e-08 32.7 0.3 3.4e-07 30.5 0.2 2.2 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EWM21792.1 - 3.8e-07 29.9 0.0 1.1e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain LSM PF01423.17 EWM21793.1 - 5.2e-16 57.9 0.0 6.8e-16 57.5 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EWM21793.1 - 0.0021 17.9 0.0 0.0031 17.3 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Feld-I_B PF09252.5 EWM21793.1 - 0.091 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Allergen Fel d I-B chain Rdx PF10262.4 EWM21794.1 - 5.7e-29 99.9 0.0 8.5e-29 99.3 0.0 1.3 1 0 0 1 1 1 1 Rdx family Thymidylat_synt PF00303.14 EWM21795.1 - 1.9e-123 410.7 0.0 3.5e-123 409.8 0.0 1.4 2 0 0 2 2 2 1 Thymidylate synthase DHFR_1 PF00186.14 EWM21795.1 - 2e-33 115.2 0.0 3.2e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 Dihydrofolate reductase Thymidylate_kin PF02223.12 EWM21796.1 - 3.7e-44 150.3 0.0 4.7e-44 149.9 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.1 EWM21796.1 - 0.0015 18.5 0.1 0.0021 18.0 0.1 1.3 1 0 0 1 1 1 1 AAA domain DUF2893 PF11459.3 EWM21796.1 - 0.059 13.1 0.1 0.47 10.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknwon function (DUF2893) AAA_16 PF13191.1 EWM21796.1 - 0.082 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 EWM21796.1 - 0.097 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EWM21796.1 - 0.12 12.1 0.9 1.3 8.8 0.6 2.5 1 1 0 1 1 1 0 Part of AAA domain TPR_4 PF07721.9 EWM21796.1 - 0.34 11.4 2.1 4 8.1 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3119 PF11317.3 EWM21798.1 - 2.9e-20 72.4 0.0 4.1e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3119) NAD_binding_10 PF13460.1 EWM21799.1 - 5.1e-06 26.6 0.0 2.3e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 NADH(P)-binding DUF1380 PF07128.7 EWM21799.1 - 0.032 14.0 0.0 0.053 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1380) SfsA PF03749.8 EWM21800.1 - 3.2e-21 75.7 0.0 2.3e-09 37.0 0.0 2.3 2 0 0 2 2 2 2 Sugar fermentation stimulation protein 2-oxoacid_dh PF00198.18 EWM21801.1 - 3.9e-72 242.2 0.0 5.2e-72 241.8 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EWM21801.1 - 1.9e-13 49.8 0.8 4.4e-13 48.6 0.2 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 EWM21801.1 - 1.1e-08 34.5 0.1 1.1e-08 34.5 0.0 2.5 3 0 0 3 3 3 1 e3 binding domain Abhydrolase_2 PF02230.11 EWM21802.1 - 1.6e-44 151.9 0.0 2.1e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EWM21802.1 - 2.3e-07 30.6 1.1 7e-07 29.1 0.4 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EWM21802.1 - 0.00012 22.0 3.7 0.00058 19.7 2.5 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 EWM21802.1 - 0.00084 19.1 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Cutinase Abhydrolase_3 PF07859.8 EWM21802.1 - 0.0086 15.6 0.1 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EWM21802.1 - 0.057 12.9 0.0 0.075 12.5 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold H_PPase PF03030.11 EWM21806.1 - 7.3e-244 811.0 33.5 8.4e-244 810.8 23.2 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase WD40 PF00400.27 EWM21807.1 - 1.1e-21 75.8 1.2 1.3e-06 28.0 0.0 7.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Peptidase_M17 PF00883.16 EWM21808.1 - 6.8e-124 412.7 0.1 9.1e-124 412.3 0.1 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 EWM21808.1 - 4.5e-16 58.7 0.5 4.5e-16 58.7 0.4 3.4 3 0 0 3 3 3 1 Cytosol aminopeptidase family, N-terminal domain LCAT PF02450.10 EWM21809.1 - 5.8e-71 239.5 0.1 1.3e-51 175.8 0.1 2.1 2 0 0 2 2 2 2 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 EWM21809.1 - 0.0085 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EWM21809.1 - 0.01 15.5 0.1 0.034 13.8 0.1 1.9 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_2 PF01674.13 EWM21809.1 - 0.18 11.1 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) ELO PF01151.13 EWM21810.1 - 5e-59 199.6 10.6 6.1e-59 199.3 7.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF2763 PF10961.3 EWM21810.1 - 1.7 9.1 9.7 0.059 13.7 1.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) 2OG-FeII_Oxy_2 PF13532.1 EWM21811.1 - 2.5e-05 24.1 0.0 6.6e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EWM21811.1 - 0.022 15.0 0.0 0.049 13.9 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily TAXi_N PF14543.1 EWM21812.1 - 9.9e-20 71.1 0.9 1.4e-19 70.6 0.6 1.2 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.18 EWM21812.1 - 2.9e-10 39.8 0.0 1e-09 38.1 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Pkinase PF00069.20 EWM21815.1 - 1.3e-14 53.9 0.0 2.1e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM21815.1 - 0.018 14.1 0.0 0.024 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase adh_short PF00106.20 EWM21817.1 - 1.7e-27 96.3 1.3 2e-27 96.1 0.4 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EWM21817.1 - 1.3e-10 41.5 0.1 1.8e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EWM21817.1 - 3.1e-10 39.9 0.4 6.8e-10 38.9 0.3 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EWM21817.1 - 3.1e-05 24.0 0.2 0.00028 20.9 0.1 2.1 2 1 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EWM21817.1 - 0.032 13.4 0.3 0.049 12.8 0.2 1.2 1 0 0 1 1 1 0 NmrA-like family tRNA-synt_2 PF00152.15 EWM21818.1 - 6.9e-75 251.8 0.0 9.2e-75 251.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EWM21818.1 - 3.9e-05 23.4 0.0 7.6e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EWM21818.1 - 0.00049 19.3 0.1 0.19 10.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti_2 PF13742.1 EWM21818.1 - 0.053 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain 7TMR-DISMED2 PF07696.6 EWM21818.1 - 0.18 11.2 0.0 0.44 9.9 0.0 1.6 1 0 0 1 1 1 0 7TMR-DISM extracellular 2 5_nucleotid PF05761.9 EWM21819.1 - 7.3e-131 436.7 0.0 8.9e-131 436.4 0.0 1.0 1 0 0 1 1 1 1 5' nucleotidase family HAD_2 PF13419.1 EWM21819.1 - 0.0008 19.6 0.5 0.19 11.9 0.0 3.7 2 2 1 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EWM21819.1 - 0.1 12.2 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like Fe-S_biosyn PF01521.15 EWM21820.1 - 1.4e-15 57.1 0.0 2e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Pkinase PF00069.20 EWM21821.1 - 1.1e-37 129.6 0.0 1.5e-37 129.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM21821.1 - 1.4e-19 70.1 0.0 2e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EWM21821.1 - 0.0015 17.5 0.0 0.0024 16.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EWM21821.1 - 0.027 14.2 0.1 0.072 12.8 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family RRM_1 PF00076.17 EWM21822.1 - 4.8e-38 128.6 0.0 1.6e-18 66.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM21822.1 - 4.8e-29 100.1 0.0 4e-14 52.3 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM21822.1 - 4.5e-14 52.0 0.0 5.7e-07 29.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EWM21822.1 - 0.0024 17.6 0.1 0.11 12.2 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EWM21822.1 - 0.0089 15.8 0.0 0.89 9.4 0.0 2.4 2 0 0 2 2 2 1 RNA binding motif MtrH PF02007.13 EWM21822.1 - 0.088 11.7 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase MtrH subunit Pkinase PF00069.20 EWM21823.1 - 1.3e-63 214.6 0.0 1.8e-63 214.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM21823.1 - 7.4e-30 103.8 0.0 1e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 EWM21823.1 - 2.4e-16 57.6 4.0 0.00067 18.7 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 EWM21823.1 - 2e-14 53.4 0.0 4.8e-10 39.4 0.0 3.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EWM21823.1 - 6.3e-14 50.5 2.1 0.00025 20.6 0.0 4.2 4 0 0 4 4 3 3 EF-hand domain EF-hand_8 PF13833.1 EWM21823.1 - 3.5e-12 45.7 5.6 0.0026 17.3 0.1 3.7 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 EWM21823.1 - 2.8e-09 35.8 7.4 0.001 18.3 0.1 4.3 4 0 0 4 4 4 2 EF hand Kinase-like PF14531.1 EWM21823.1 - 2e-06 26.9 0.0 0.0039 16.1 0.0 2.3 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 EWM21823.1 - 0.00024 20.9 0.0 0.053 13.2 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family SPARC_Ca_bdg PF10591.4 EWM21823.1 - 0.015 15.3 0.0 1.4 8.9 0.0 2.7 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EWM21823.1 - 0.058 13.1 0.1 2.2 8.0 0.0 2.6 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand PACT_coil_coil PF10495.4 EWM21823.1 - 0.39 10.6 2.8 0.71 9.8 0.1 2.7 4 0 0 4 4 4 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein Sod_Fe_C PF02777.13 EWM21824.1 - 5.9e-39 132.1 0.5 7.8e-38 128.5 0.0 2.2 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EWM21824.1 - 2.8e-28 97.9 0.4 4.8e-28 97.2 0.3 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Beta_elim_lyase PF01212.16 EWM21824.1 - 0.035 13.2 0.0 0.043 12.9 0.0 1.1 1 0 0 1 1 1 0 Beta-eliminating lyase Ras PF00071.17 EWM21825.1 - 7.3e-56 188.0 0.0 8.7e-56 187.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EWM21825.1 - 1.6e-18 67.3 0.0 2.3e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EWM21825.1 - 5.8e-12 45.2 0.0 6.6e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EWM21825.1 - 2.2e-05 23.7 0.0 2.7e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EWM21825.1 - 2.4e-05 24.2 0.0 3.4e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EWM21825.1 - 0.0011 18.4 0.0 0.0087 15.5 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EWM21825.1 - 0.0026 17.0 0.0 0.0033 16.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EWM21825.1 - 0.0028 17.8 0.0 0.0042 17.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EWM21825.1 - 0.0073 15.5 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EWM21825.1 - 0.02 14.6 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_10 PF12846.2 EWM21825.1 - 0.044 13.2 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Septin PF00735.13 EWM21825.1 - 0.055 12.4 0.0 0.093 11.7 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_24 PF13479.1 EWM21825.1 - 0.1 12.1 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain Peptidase_M76 PF09768.4 EWM21826.1 - 1.2e-49 168.1 6.5 1.4e-49 167.8 4.5 1.1 1 0 0 1 1 1 1 Peptidase M76 family RIC1 PF07064.8 EWM21827.1 - 8.2e-10 38.5 0.1 5.4e-09 35.8 0.0 2.3 2 1 0 2 2 2 1 RIC1 WD40 PF00400.27 EWM21827.1 - 0.00023 20.9 0.5 0.67 9.9 0.0 4.4 4 0 0 4 4 4 1 WD domain, G-beta repeat GATase_2 PF00310.16 EWM21828.1 - 2.2e-17 62.8 0.0 3e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 EWM21828.1 - 2.1e-16 60.0 0.0 3.6e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EWM21828.1 - 1.3e-14 54.0 0.0 2e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 EWM21828.1 - 1.2e-08 34.7 0.0 3e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 EWM21828.1 - 1.5e-05 23.8 0.0 2.2e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II ADH_zinc_N PF00107.21 EWM21828.1 - 0.11 12.0 0.0 3.2 7.2 0.0 2.4 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Methyltransf_16 PF10294.4 EWM21829.1 - 1.7e-16 60.1 0.1 1.8e-14 53.5 0.1 2.4 1 1 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EWM21829.1 - 7.6e-07 28.6 0.1 1.2e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EWM21829.1 - 0.0021 18.6 0.0 0.0042 17.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EWM21829.1 - 0.0029 16.7 0.1 0.0047 16.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DUF1610 PF07754.6 EWM21829.1 - 0.018 15.1 4.2 2.1 8.5 0.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) Cons_hypoth95 PF03602.10 EWM21829.1 - 0.035 13.4 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_26 PF13659.1 EWM21829.1 - 0.036 14.0 0.3 0.075 13.0 0.2 1.7 1 0 0 1 1 1 0 Methyltransferase domain Cyclin_N PF00134.18 EWM21830.1 - 3.6e-35 120.3 0.4 7.5e-35 119.2 0.2 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EWM21830.1 - 9.8e-23 80.3 0.3 4.3e-22 78.2 0.0 2.1 2 1 1 3 3 3 1 Cyclin, C-terminal domain YejG PF13989.1 EWM21830.1 - 0.028 14.4 0.4 0.049 13.7 0.3 1.3 1 0 0 1 1 1 0 YejG-like protein ABC2_membrane PF01061.19 EWM21831.1 - 1.7e-37 128.6 20.3 1.7e-37 128.6 14.0 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 EWM21831.1 - 8.2e-22 77.9 0.0 1.6e-21 77.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 EWM21831.1 - 2.5e-09 36.6 19.5 3.6e-09 36.1 13.5 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.2 EWM21831.1 - 1.3e-05 24.1 15.6 7.7e-05 21.6 10.8 2.1 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.1 EWM21831.1 - 1.7e-05 24.9 0.1 0.00043 20.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EWM21831.1 - 0.00058 19.3 0.3 0.0013 18.2 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EWM21831.1 - 0.0017 17.5 0.5 0.0031 16.7 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EWM21831.1 - 0.038 14.1 0.1 0.21 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EWM21831.1 - 0.11 11.4 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ArgK PF03308.11 EWM21831.1 - 0.13 11.0 0.0 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_16 PF13191.1 EWM21831.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Zip PF02535.17 EWM21832.1 - 5.5e-39 134.0 11.9 8.6e-39 133.3 8.2 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Vps55 PF04133.9 EWM21832.1 - 0.04 13.6 0.3 0.04 13.6 0.2 2.0 2 0 0 2 2 2 0 Vacuolar protein sorting 55 RHD3 PF05879.7 EWM21833.1 - 5.2e-38 130.4 0.0 9.3e-38 129.6 0.0 1.3 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) AAA_10 PF12846.2 EWM21833.1 - 0.0035 16.8 0.0 0.0058 16.1 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain MMR_HSR1 PF01926.18 EWM21833.1 - 0.076 12.9 0.5 1.2 9.1 0.2 2.5 1 1 1 2 2 2 0 50S ribosome-binding GTPase DUF3832 PF12909.2 EWM21833.1 - 0.079 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3832) NB-ARC PF00931.17 EWM21833.1 - 0.18 10.6 0.0 0.28 9.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain PrmA PF06325.8 EWM21834.1 - 6.7e-52 176.4 0.0 3.1e-51 174.2 0.0 1.8 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EWM21834.1 - 7.4e-06 25.9 0.0 1.3e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM21834.1 - 3.2e-05 23.5 0.1 6.6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EWM21834.1 - 0.0013 18.1 0.1 0.0023 17.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EWM21834.1 - 0.0021 18.6 0.0 0.0043 17.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Rib PF08428.5 EWM21834.1 - 0.015 15.0 0.0 0.041 13.6 0.0 1.7 1 0 0 1 1 1 0 Rib/alpha-like repeat Methyltransf_23 PF13489.1 EWM21834.1 - 0.034 13.8 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PfkB PF00294.19 EWM21835.1 - 6.5e-22 78.0 2.1 1.3e-21 77.0 0.5 2.0 2 0 0 2 2 2 1 pfkB family carbohydrate kinase SIS PF01380.17 EWM21835.1 - 1.7e-21 76.1 0.5 4.8e-21 74.7 0.3 1.8 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.1 EWM21835.1 - 5.2e-08 32.6 0.5 2.2e-05 24.1 0.0 2.8 1 1 1 2 2 2 2 SIS domain DUF2529 PF10740.4 EWM21835.1 - 0.043 13.2 0.1 0.32 10.4 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2529) Ham1p_like PF01725.11 EWM21836.1 - 1.2e-48 165.0 0.0 1.4e-48 164.8 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Methyltransf_21 PF05050.7 EWM21837.1 - 4.2e-18 65.8 0.0 6.9e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_18 PF12847.2 EWM21837.1 - 0.011 16.2 0.0 0.029 14.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Glyco_trans_1_3 PF13528.1 EWM21837.1 - 0.087 12.0 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 Met_10 PF02475.11 EWM21837.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_21 PF05050.7 EWM21838.1 - 6.3e-18 65.2 0.0 1.1e-17 64.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain Glyco_transf_28 PF03033.15 EWM21838.1 - 0.0056 16.4 0.0 0.019 14.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain Methyltransf_18 PF12847.2 EWM21838.1 - 0.017 15.6 0.0 0.043 14.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Glyco_trans_1_3 PF13528.1 EWM21838.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 Met_10 PF02475.11 EWM21838.1 - 0.22 11.1 0.0 0.38 10.2 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Bromodomain PF00439.20 EWM21839.1 - 1.1e-22 79.7 0.0 1.3e-10 41.0 0.0 2.3 2 0 0 2 2 2 2 Bromodomain Epimerase PF01370.16 EWM21840.1 - 9.3e-51 172.5 0.0 1.3e-50 172.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EWM21840.1 - 2.2e-26 91.5 0.4 5.3e-26 90.3 0.3 1.7 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit Polysacc_synt_2 PF02719.10 EWM21840.1 - 3.3e-15 55.7 0.0 7.8e-14 51.2 0.0 2.6 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EWM21840.1 - 5e-12 45.1 0.0 9.2e-12 44.2 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EWM21840.1 - 2.2e-11 43.1 0.0 3.7e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EWM21840.1 - 3.8e-10 39.1 0.0 5.5e-09 35.3 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EWM21840.1 - 4.2e-09 36.6 0.0 8e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EWM21840.1 - 1.3e-08 34.9 0.0 2.3e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EWM21840.1 - 7.3e-06 25.7 0.0 1.5e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 KR domain UDPG_MGDP_dh_N PF03721.9 EWM21840.1 - 0.0025 17.2 0.0 0.0039 16.6 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.19 EWM21840.1 - 0.09 11.6 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trns_repr_metal PF02583.12 EWM21840.1 - 0.1 12.8 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 Metal-sensitive transcriptional repressor Abhydrolase_6 PF12697.2 EWM21842.1 - 7.5e-10 39.0 0.0 1.9e-09 37.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM21842.1 - 0.00017 21.4 0.0 0.00037 20.2 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EWM21842.1 - 0.00021 20.9 0.0 0.0014 18.2 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.6 EWM21842.1 - 0.023 14.4 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_8 PF06259.7 EWM21842.1 - 0.057 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase COPIIcoated_ERV PF07970.7 EWM21843.1 - 3.4e-27 95.5 0.3 3e-26 92.4 0.0 2.1 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EWM21843.1 - 8.2e-22 77.0 0.3 1.5e-21 76.1 0.2 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Thioredoxin PF00085.15 EWM21843.1 - 2e-20 72.3 0.1 3.4e-20 71.6 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EWM21843.1 - 0.015 15.4 0.1 0.036 14.2 0.1 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EWM21843.1 - 0.021 14.9 0.1 0.091 12.8 0.0 2.0 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_7 PF13899.1 EWM21843.1 - 0.036 14.0 0.1 0.076 13.0 0.1 1.6 1 0 0 1 1 1 0 Thioredoxin-like Tctex-1 PF03645.8 EWM21844.1 - 3.4e-23 81.4 0.5 3.4e-23 81.4 0.3 1.4 2 0 0 2 2 2 1 Tctex-1 family B2 PF11473.3 EWM21844.1 - 0.055 13.0 0.1 0.099 12.2 0.0 1.5 2 0 0 2 2 2 0 RNA binding protein B2 Med3 PF11593.3 EWM21845.1 - 1.7 7.8 7.1 3.1 6.9 4.9 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Snf7 PF03357.16 EWM21846.1 - 2.4e-28 98.6 11.6 3.8e-28 98.0 8.0 1.4 1 1 0 1 1 1 1 Snf7 MutS_III PF05192.13 EWM21846.1 - 0.011 15.5 0.7 0.015 15.0 0.5 1.3 1 0 0 1 1 1 0 MutS domain III OmpH PF03938.9 EWM21846.1 - 0.12 12.3 6.3 0.22 11.4 4.4 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HALZ PF02183.13 EWM21846.1 - 0.15 11.7 5.5 9.8 5.9 0.8 3.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper Metallophos PF00149.23 EWM21847.1 - 1.3e-29 103.0 0.0 2.7e-29 102.0 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase His_Phos_1 PF00300.17 EWM21847.1 - 9e-20 71.3 0.1 1.6e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) EF-hand_7 PF13499.1 EWM21847.1 - 0.031 14.4 0.1 0.15 12.2 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain pair DUF4194 PF13835.1 EWM21847.1 - 0.09 12.2 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4194) EF-hand_6 PF13405.1 EWM21847.1 - 0.12 12.2 0.5 0.56 10.2 0.3 2.1 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.27 EWM21847.1 - 0.15 11.4 2.3 0.22 10.9 0.6 2.1 2 0 0 2 2 2 0 EF hand Myc_N PF01056.13 EWM21848.1 - 0.17 11.0 4.8 0.42 9.7 3.3 1.6 1 1 0 1 1 1 0 Myc amino-terminal region PCNP PF15473.1 EWM21848.1 - 0.31 11.3 3.5 0.55 10.5 2.2 1.6 1 1 0 1 1 1 0 PEST, proteolytic signal-containing nuclear protein family Cytochrom_C1 PF02167.10 EWM21849.1 - 4.2e-79 265.2 0.0 5e-79 264.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 EWM21849.1 - 0.00086 19.4 0.0 0.0021 18.1 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 EWM21849.1 - 0.14 13.0 0.8 0.31 11.8 0.1 2.0 2 1 0 2 2 2 0 Cytochrome c Bromodomain PF00439.20 EWM21850.1 - 9.4e-10 38.2 0.0 0.0003 20.6 0.0 2.2 2 0 0 2 2 2 2 Bromodomain Acetyltransf_1 PF00583.19 EWM21851.1 - 7.4e-14 51.5 0.2 1.5e-13 50.5 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EWM21851.1 - 3.3e-10 39.9 0.0 6.3e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EWM21851.1 - 1.2e-06 28.6 0.0 2.7e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EWM21851.1 - 1.7e-05 24.5 0.0 3.3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EWM21851.1 - 0.00073 19.4 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EWM21851.1 - 0.0021 18.2 0.0 0.0055 16.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FGGY_N PF00370.16 EWM21852.1 - 1.4e-23 83.5 0.0 6.4e-19 68.2 0.0 2.7 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 EWM21852.1 - 5.4e-22 78.3 0.9 1.4e-21 77.0 0.5 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain MreB_Mbl PF06723.8 EWM21852.1 - 0.083 11.4 0.4 0.21 10.1 0.0 1.8 2 0 0 2 2 2 0 MreB/Mbl protein UPF0172 PF03665.8 EWM21853.1 - 2.2e-31 108.9 0.1 9.5e-31 106.8 0.1 1.8 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.16 EWM21853.1 - 0.0097 15.6 0.0 0.017 14.8 0.0 1.5 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EWM21853.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain MutS_V PF00488.16 EWM21854.1 - 1.4e-48 165.3 0.0 1.1e-47 162.4 0.0 2.3 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EWM21854.1 - 6.8e-30 104.3 2.4 1.2e-29 103.5 1.7 1.4 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 EWM21854.1 - 8.9e-05 22.5 0.0 0.00018 21.6 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV CCDC142 PF14923.1 EWM21854.1 - 0.064 11.5 0.1 2.5 6.2 0.0 2.3 2 0 0 2 2 2 0 Coiled-coil protein 142 PhyH PF05721.8 EWM21858.1 - 0.018 15.0 0.0 0.08 12.9 0.0 2.0 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Cupin_2 PF07883.6 EWM21858.1 - 0.13 11.7 0.2 0.58 9.6 0.0 2.1 2 0 0 2 2 2 0 Cupin domain TPR_11 PF13414.1 EWM21859.1 - 1.6e-14 53.2 4.8 1.4e-10 40.6 1.4 2.3 1 1 2 3 3 3 2 TPR repeat Apc3 PF12895.2 EWM21859.1 - 7.3e-11 42.0 0.0 5.4e-07 29.6 0.0 2.0 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 EWM21859.1 - 3.8e-10 38.8 0.7 0.0023 17.6 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 EWM21859.1 - 4.3e-10 39.3 3.6 0.0006 20.2 0.0 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EWM21859.1 - 6.1e-09 36.0 0.2 4.8e-05 23.6 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EWM21859.1 - 6.7e-08 32.9 6.4 4.6e-05 23.9 1.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EWM21859.1 - 2.6e-07 29.9 0.1 0.02 14.6 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EWM21859.1 - 1.4e-05 24.9 3.2 0.00096 19.0 1.7 2.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EWM21859.1 - 3.1e-05 23.3 0.0 0.049 13.2 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EWM21859.1 - 6.2e-05 22.7 0.7 0.037 13.8 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EWM21859.1 - 0.00061 19.4 0.1 2.1 8.3 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EWM21859.1 - 0.003 17.6 0.0 2.1 8.7 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.1 EWM21859.1 - 0.033 13.2 0.4 0.14 11.2 0.2 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EWM21859.1 - 0.046 13.9 0.6 1.3 9.2 0.1 2.2 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation TPR_6 PF13174.1 EWM21859.1 - 0.1 13.1 0.2 74 4.1 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.1 EWM21859.1 - 0.12 12.4 2.3 0.45 10.6 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat 5_nucleotid PF05761.9 EWM21860.1 - 1.3e-137 458.9 0.0 1.6e-137 458.7 0.0 1.0 1 0 0 1 1 1 1 5' nucleotidase family HAD_2 PF13419.1 EWM21860.1 - 0.0002 21.6 0.0 0.43 10.7 0.0 2.8 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EWM21860.1 - 0.0076 15.9 0.0 0.02 14.5 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Tropomyosin_1 PF12718.2 EWM21860.1 - 0.011 15.6 0.5 0.017 14.9 0.4 1.2 1 0 0 1 1 1 0 Tropomyosin like Pkinase PF00069.20 EWM21861.1 - 1.2e-48 165.5 0.0 2.1e-48 164.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM21861.1 - 2.6e-23 82.4 0.0 4.2e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_I PF08311.7 EWM21861.1 - 3.9e-10 39.6 0.0 8.5e-10 38.4 0.0 1.6 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 APH PF01636.18 EWM21861.1 - 4.1e-06 26.7 4.6 0.0035 17.1 0.1 3.4 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EWM21861.1 - 0.023 13.6 0.0 0.045 12.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 EWM21861.1 - 0.025 13.9 0.0 0.055 12.8 0.0 1.5 1 0 0 1 1 1 0 RIO1 family AIRS_C PF02769.17 EWM21862.1 - 4.9e-05 23.3 0.3 0.00049 20.1 0.2 2.5 1 1 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EWM21862.1 - 0.099 12.8 0.8 0.21 11.8 0.0 1.9 2 0 0 2 2 2 0 AIR synthase related protein, N-terminal domain GTP1_OBG PF01018.17 EWM21863.1 - 2.7e-25 88.8 9.9 2.7e-25 88.8 6.9 3.2 4 0 0 4 4 4 1 GTP1/OBG MMR_HSR1 PF01926.18 EWM21863.1 - 2.6e-19 69.2 0.0 5.7e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EWM21863.1 - 1.7e-07 30.6 0.0 1.2e-06 27.9 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B ArgK PF03308.11 EWM21863.1 - 0.0031 16.3 0.7 1.3 7.7 0.0 2.7 3 0 0 3 3 3 2 ArgK protein Arf PF00025.16 EWM21863.1 - 0.039 13.1 0.0 0.2 10.8 0.0 2.1 1 1 0 1 1 1 0 ADP-ribosylation factor family Dynamin_N PF00350.18 EWM21863.1 - 0.13 12.0 0.0 6 6.6 0.0 2.4 1 1 1 2 2 2 0 Dynamin family AP2 PF00847.15 EWM21866.1 - 0.58 10.3 0.1 0.58 10.3 0.0 3.5 4 0 0 4 4 4 0 AP2 domain U1snRNP70_N PF12220.3 EWM21867.1 - 0.55 10.6 3.7 15 5.9 0.0 2.7 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Pyr_redox_3 PF13738.1 EWM21868.1 - 6.8e-07 29.5 0.3 0.00063 19.8 0.0 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EWM21868.1 - 5e-06 26.5 0.0 0.00039 20.3 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EWM21868.1 - 0.00019 21.3 0.0 0.00057 19.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EWM21868.1 - 0.0024 17.6 0.0 0.0086 15.8 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 EWM21868.1 - 0.0027 16.8 0.2 0.78 8.7 0.0 2.3 2 0 0 2 2 2 2 Thi4 family Pyr_redox PF00070.22 EWM21868.1 - 0.012 16.0 0.0 5.2 7.5 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EWM21868.1 - 0.075 12.5 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Kelch_1 PF01344.20 EWM21870.1 - 1.9e-24 84.8 1.5 2.1e-07 30.3 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 EWM21870.1 - 3.5e-18 64.9 4.2 0.00041 20.4 0.0 6.5 5 2 1 6 6 6 4 Kelch motif Kelch_2 PF07646.10 EWM21870.1 - 1.6e-11 43.4 3.9 0.00033 20.2 0.0 5.6 6 0 0 6 6 6 3 Kelch motif Kelch_4 PF13418.1 EWM21870.1 - 5.9e-06 25.9 16.0 0.029 14.1 0.0 7.0 8 0 0 8 8 8 2 Galactose oxidase, central domain Kelch_5 PF13854.1 EWM21870.1 - 0.0005 19.9 3.4 1.2 9.1 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 EWM21870.1 - 0.00067 19.7 14.1 1 9.6 0.2 5.8 5 2 0 5 5 5 3 Galactose oxidase, central domain ubiquitin PF00240.18 EWM21871.1 - 9.4e-08 31.3 0.0 1.3e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EWM21871.1 - 0.016 14.8 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF4006 PF13179.1 EWM21871.1 - 0.52 9.9 1.8 0.8 9.2 0.2 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF4006) TPR_12 PF13424.1 EWM21872.1 - 2.1e-31 107.6 30.2 5.7e-13 48.6 0.1 6.3 3 3 2 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.1 EWM21872.1 - 1.1e-13 50.5 23.6 2e-05 24.1 0.0 5.5 4 1 2 6 6 6 5 TPR repeat TPR_7 PF13176.1 EWM21872.1 - 1.2e-10 40.2 18.8 0.098 12.5 0.2 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.23 EWM21872.1 - 3.3e-09 35.9 20.9 0.031 13.8 0.1 7.0 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 EWM21872.1 - 6.7e-07 28.6 7.1 2.4 8.1 0.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.12 EWM21872.1 - 4.8e-05 22.9 37.3 0.081 12.8 0.5 8.7 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 EWM21872.1 - 6.5e-05 23.4 38.2 0.0044 17.6 0.5 6.8 6 2 2 8 8 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 EWM21872.1 - 0.0004 20.7 41.3 1 10.1 0.1 9.4 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.1 EWM21872.1 - 0.00063 20.0 20.4 0.004 17.4 0.1 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 EWM21872.1 - 0.0059 16.7 5.9 13 6.2 0.0 6.7 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_10 PF13374.1 EWM21872.1 - 0.0094 15.8 0.5 0.0094 15.8 0.3 9.2 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_6 PF13174.1 EWM21872.1 - 0.04 14.3 18.8 0.87 10.1 0.0 6.8 7 0 0 7 7 5 0 Tetratricopeptide repeat SNAP PF14938.1 EWM21872.1 - 0.04 13.0 0.2 0.04 13.0 0.2 3.5 4 0 0 4 4 4 0 Soluble NSF attachment protein, SNAP Vps39_1 PF10366.4 EWM21872.1 - 0.19 11.7 0.1 1.5 8.8 0.0 2.5 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 TPR_5 PF12688.2 EWM21872.1 - 4.5 7.3 14.5 0.069 13.1 1.6 3.7 4 1 1 5 5 5 0 Tetratrico peptide repeat DUF633 PF04816.7 EWM21873.1 - 6.5e-15 55.0 0.0 1.8e-14 53.5 0.0 1.7 1 1 0 1 1 1 1 Family of unknown function (DUF633) Methyltransf_18 PF12847.2 EWM21873.1 - 2.2e-05 24.9 0.1 0.00012 22.6 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM21873.1 - 0.00027 20.5 0.0 0.0013 18.3 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EWM21873.1 - 0.03 13.6 0.0 0.054 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Ail_Lom PF06316.6 EWM21873.1 - 0.13 11.7 0.1 0.19 11.2 0.1 1.2 1 0 0 1 1 1 0 Enterobacterial Ail/Lom protein Adaptin_N PF01602.15 EWM21875.1 - 1.5e-110 370.0 0.5 1.8e-110 369.7 0.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EWM21875.1 - 2.1e-08 34.2 0.4 4.2e-06 26.7 0.0 3.3 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 AP3B1_C PF14796.1 EWM21875.1 - 6.7e-08 32.3 0.0 1.8e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Clathrin-adaptor complex-3 beta-1 subunit C-terminal HEAT_2 PF13646.1 EWM21875.1 - 3.2e-06 27.3 12.8 2.6e-05 24.4 1.6 4.7 3 1 1 4 4 4 1 HEAT repeats SPO22 PF08631.5 EWM21875.1 - 0.00072 18.7 0.7 0.0016 17.5 0.0 1.8 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like HEAT PF02985.17 EWM21875.1 - 0.0018 18.1 5.8 0.47 10.6 0.0 4.9 5 1 1 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 EWM21875.1 - 0.72 10.4 14.8 0.078 13.4 0.6 5.7 5 2 1 7 7 7 0 HEAT-like repeat Adaptin_N PF01602.15 EWM21876.1 - 1.4e-103 347.0 0.5 1.7e-103 346.7 0.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region AP3B1_C PF14796.1 EWM21876.1 - 6.3e-08 32.4 0.0 1.7e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Clathrin-adaptor complex-3 beta-1 subunit C-terminal Cnd1 PF12717.2 EWM21876.1 - 4.9e-07 29.7 0.1 3.9e-06 26.8 0.0 2.4 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EWM21876.1 - 2.8e-06 27.5 12.8 2.4e-05 24.5 1.6 4.8 3 1 1 4 4 4 1 HEAT repeats SPO22 PF08631.5 EWM21876.1 - 0.00075 18.6 0.0 0.0015 17.6 0.0 1.4 1 0 0 1 1 1 1 Meiosis protein SPO22/ZIP4 like HEAT PF02985.17 EWM21876.1 - 0.0014 18.5 5.7 0.45 10.7 0.0 4.9 5 1 1 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 EWM21876.1 - 0.7 10.4 15.0 0.075 13.5 0.6 5.8 5 2 1 7 7 7 0 HEAT-like repeat Cellsynth_D PF03500.8 EWM21877.1 - 0.091 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Cellulose synthase subunit D Octopine_DH PF02317.12 EWM21877.1 - 0.16 11.6 0.1 0.47 10.1 0.0 1.7 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Rho_N PF07498.7 EWM21877.1 - 0.22 11.3 3.7 4.9 6.9 0.2 2.7 3 0 0 3 3 3 0 Rho termination factor, N-terminal domain Ribosomal_S6e PF01092.14 EWM21878.1 - 6.4e-58 193.9 1.5 1.2e-57 193.0 1.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e AAA_12 PF13087.1 EWM21879.1 - 1.1e-56 191.4 0.0 4.5e-56 189.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EWM21879.1 - 5.3e-50 170.2 0.1 1.2e-49 169.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EWM21879.1 - 1.9e-13 49.9 1.5 8.4e-13 47.8 1.0 2.2 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EWM21879.1 - 8.2e-10 38.5 4.8 3.6e-09 36.4 0.0 3.0 2 2 1 3 3 2 1 AAA domain UvrD-helicase PF00580.16 EWM21879.1 - 0.00012 21.4 0.1 0.00064 19.1 0.1 1.9 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain PhoH PF02562.11 EWM21879.1 - 0.0018 17.5 0.0 0.043 13.0 0.0 2.8 3 0 0 3 3 3 1 PhoH-like protein Viral_helicase1 PF01443.13 EWM21879.1 - 0.0083 15.6 0.0 0.39 10.1 0.0 2.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 EWM21879.1 - 0.022 14.6 0.0 0.055 13.3 0.0 1.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_16 PF13191.1 EWM21879.1 - 0.026 14.4 1.9 0.044 13.7 0.6 1.8 1 1 0 1 1 1 0 AAA ATPase domain PIF1 PF05970.9 EWM21879.1 - 0.028 13.3 0.0 1.3 7.8 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase IstB_IS21 PF01695.12 EWM21879.1 - 0.062 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.4 EWM21879.1 - 0.078 11.9 0.3 0.31 9.9 0.0 2.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 EWM21879.1 - 0.092 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain WD40 PF00400.27 EWM21880.1 - 2.8e-09 36.4 0.0 0.036 13.9 0.0 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat PD40 PF07676.7 EWM21880.1 - 0.076 12.7 0.0 1.2 8.8 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 EWM21880.1 - 0.12 10.7 0.0 0.25 9.6 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain GTP_EFTU PF00009.22 EWM21881.1 - 1.3e-45 155.1 0.0 1.9e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EWM21881.1 - 3.6e-05 23.5 0.0 9.5e-05 22.1 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EWM21881.1 - 7.7e-05 22.6 0.0 0.00017 21.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 EWM21881.1 - 0.00028 20.9 0.0 0.00055 19.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SRPRB PF09439.5 EWM21881.1 - 0.047 12.9 0.0 0.17 11.0 0.0 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Miro PF08477.8 EWM21881.1 - 0.093 13.2 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein MobB PF03205.9 EWM21881.1 - 0.1 12.2 0.1 0.41 10.3 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B adh_short PF00106.20 EWM21882.1 - 9.1e-28 97.2 0.7 1.2e-27 96.9 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EWM21882.1 - 4.4e-14 52.5 0.2 6.4e-14 52.0 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EWM21882.1 - 5.5e-10 39.4 0.0 7.3e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EWM21882.1 - 0.00095 18.1 0.1 0.0014 17.5 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein UPF0139 PF03669.8 EWM21883.1 - 2.6e-11 42.9 0.0 3.2e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) LMBR1 PF04791.11 EWM21883.1 - 0.039 12.5 2.2 0.049 12.2 1.5 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Sprouty PF05210.8 EWM21883.1 - 0.18 11.8 0.9 0.26 11.3 0.5 1.4 1 1 0 1 1 1 0 Sprouty protein (Spry) DUF4131 PF13567.1 EWM21883.1 - 3.4 7.0 6.8 5.8 6.2 4.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) potato_inhibit PF00280.13 EWM21884.1 - 7.6e-24 83.6 0.2 1.1e-23 83.1 0.1 1.2 1 0 0 1 1 1 1 Potato inhibitor I family Inhibitor_I78 PF11720.3 EWM21884.1 - 0.019 14.6 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase inhibitor I78 family potato_inhibit PF00280.13 EWM21885.1 - 1.8e-23 82.4 0.1 2.5e-23 81.9 0.1 1.2 1 0 0 1 1 1 1 Potato inhibitor I family Inhibitor_I78 PF11720.3 EWM21885.1 - 0.0011 18.6 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I78 family DUF2259 PF10016.4 EWM21885.1 - 0.042 13.5 0.0 0.057 13.1 0.0 1.1 1 0 0 1 1 1 0 Predicted secreted protein (DUF2259) Bacillus_HBL PF05791.6 EWM21886.1 - 0.0017 17.7 0.5 0.0017 17.7 0.4 2.5 2 1 1 3 3 3 1 Bacillus haemolytic enterotoxin (HBL) SHIPPO-rpt PF07004.7 EWM21887.1 - 7.6e-10 39.1 17.6 0.012 16.4 0.0 5.6 5 0 0 5 5 5 4 Sperm-tail PG-rich repeat HrcA_DNA-bdg PF03444.10 EWM21888.1 - 0.033 13.6 0.1 0.07 12.5 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Toxin_22 PF08092.6 EWM21888.1 - 0.082 12.7 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Magi peptide toxin family DEAD PF00270.24 EWM21889.1 - 2e-26 92.5 0.0 4.1e-16 58.9 0.0 2.5 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EWM21889.1 - 5.6e-15 54.9 0.1 1.3e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EWM21889.1 - 0.00095 19.0 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.11 EWM21889.1 - 0.12 11.5 0.1 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein DNA_pol_A_exo1 PF01612.15 EWM21890.1 - 6.3e-12 45.3 0.0 9.5e-12 44.7 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease Sel1 PF08238.7 EWM21891.1 - 3.3e-12 46.6 0.0 0.00042 20.8 0.0 5.1 5 1 0 5 5 5 3 Sel1 repeat DUF1955 PF09205.5 EWM21891.1 - 0.19 11.2 1.7 1 8.8 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1955) Beta-lactamase PF00144.19 EWM21892.1 - 6.9e-37 127.2 0.1 1.8e-32 112.6 0.0 2.3 2 0 0 2 2 2 2 Beta-lactamase ABC1 PF03109.11 EWM21892.1 - 4.8e-29 100.7 0.0 9e-29 99.8 0.0 1.5 1 0 0 1 1 1 1 ABC1 family FYVE PF01363.16 EWM21892.1 - 6.4e-10 38.7 14.1 1.3e-09 37.7 9.8 1.5 1 0 0 1 1 1 1 FYVE zinc finger SCP2 PF02036.12 EWM21892.1 - 0.00027 21.1 0.0 0.00064 19.9 0.0 1.6 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EWM21892.1 - 0.01 15.8 0.0 0.036 14.0 0.0 1.8 2 0 0 2 2 2 0 Alkyl sulfatase C-terminal FYVE_2 PF02318.11 EWM21892.1 - 0.66 9.8 6.9 1.5 8.6 4.8 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger NUDIX PF00293.23 EWM21893.1 - 6.2e-21 74.4 0.0 9.2e-21 73.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain AAA PF00004.24 EWM21895.1 - 7.9e-33 113.4 0.0 1.8e-32 112.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EWM21895.1 - 1.3e-05 25.2 0.1 0.0011 18.9 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EWM21895.1 - 2.9e-05 24.2 0.0 0.001 19.1 0.0 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EWM21895.1 - 7.6e-05 21.8 0.0 0.00013 21.1 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EWM21895.1 - 0.00028 21.6 0.0 0.001 19.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EWM21895.1 - 0.00038 20.3 0.0 0.00062 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EWM21895.1 - 0.00038 20.3 0.0 0.0013 18.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.9 EWM21895.1 - 0.00099 19.0 0.0 0.0025 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EWM21895.1 - 0.0026 16.7 0.0 0.0045 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 EWM21895.1 - 0.0035 16.7 0.3 0.0086 15.5 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EWM21895.1 - 0.0043 15.8 0.3 0.0099 14.6 0.1 1.6 1 1 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 EWM21895.1 - 0.0056 16.4 0.1 0.08 12.6 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EWM21895.1 - 0.0058 15.8 0.1 0.013 14.6 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EWM21895.1 - 0.0075 16.2 0.5 0.015 15.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.7 EWM21895.1 - 0.0082 15.2 0.0 0.016 14.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Parvo_NS1 PF01057.12 EWM21895.1 - 0.0088 14.9 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.13 EWM21895.1 - 0.013 15.1 0.0 0.031 13.9 0.0 1.6 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_25 PF13481.1 EWM21895.1 - 0.016 14.6 0.4 0.082 12.3 0.2 1.9 1 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EWM21895.1 - 0.017 15.4 0.0 0.036 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EWM21895.1 - 0.019 14.7 0.0 0.067 12.9 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 EWM21895.1 - 0.023 14.8 0.0 0.068 13.3 0.0 1.8 2 0 0 2 2 1 0 RNA helicase Sigma54_activat PF00158.21 EWM21895.1 - 0.041 13.3 0.0 0.089 12.2 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain UPF0047 PF01894.12 EWM21895.1 - 0.053 13.3 0.1 0.091 12.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0047 NACHT PF05729.7 EWM21895.1 - 0.056 13.1 0.1 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain TBD PF12845.2 EWM21895.1 - 0.08 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 TBD domain Zot PF05707.7 EWM21895.1 - 0.1 12.0 0.1 18 4.7 0.0 2.7 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_24 PF13479.1 EWM21895.1 - 0.1 12.1 0.1 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 EWM21895.1 - 0.14 12.1 1.4 6.7 6.5 0.3 2.2 1 1 1 2 2 2 0 AAA domain AAA PF00004.24 EWM21896.1 - 4e-38 130.6 0.0 7.6e-38 129.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EWM21896.1 - 6.6e-08 32.3 0.0 1.6e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.7 EWM21896.1 - 5.9e-07 28.7 0.0 1.3e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EWM21896.1 - 1.6e-06 27.8 0.1 2.3e-05 24.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EWM21896.1 - 8.3e-05 22.7 0.1 0.00095 19.3 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EWM21896.1 - 0.00038 20.1 2.3 0.0013 18.3 0.4 2.5 2 0 0 2 2 2 1 Part of AAA domain TIP49 PF06068.8 EWM21896.1 - 0.00044 19.0 0.0 0.00077 18.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 EWM21896.1 - 0.00045 19.6 0.0 0.001 18.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 EWM21896.1 - 0.00075 19.5 2.6 0.0049 16.8 0.1 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EWM21896.1 - 0.00084 18.7 0.6 0.18 11.1 0.2 2.6 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EWM21896.1 - 0.0041 17.9 0.0 0.0078 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EWM21896.1 - 0.013 14.6 0.1 0.034 13.3 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EWM21896.1 - 0.019 14.8 0.0 0.058 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EWM21896.1 - 0.023 14.5 0.0 0.052 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 EWM21896.1 - 0.033 14.1 0.0 0.074 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Parvo_NS1 PF01057.12 EWM21896.1 - 0.04 12.7 0.0 0.067 12.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 EWM21896.1 - 0.04 13.3 0.0 0.55 9.6 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EWM21896.1 - 0.042 13.9 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 EWM21896.1 - 0.05 13.5 0.0 0.14 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EWM21896.1 - 0.051 13.8 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EWM21896.1 - 0.096 12.8 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.11 EWM21896.1 - 0.16 11.1 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein CHD5 PF04420.9 EWM21897.1 - 0.003 17.2 0.1 0.0038 16.9 0.0 1.2 1 0 0 1 1 1 1 CHD5-like protein DUF4231 PF14015.1 EWM21897.1 - 0.089 12.7 0.5 0.14 12.1 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) JmjC PF02373.17 EWM21898.1 - 2.9e-41 140.2 0.1 7.2e-41 139.0 0.0 1.7 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.12 EWM21898.1 - 5.7e-14 51.3 0.1 5.7e-14 51.3 0.0 2.3 2 0 0 2 2 2 1 jmjN domain zinc-ribbons_6 PF07191.7 EWM21898.1 - 0.0049 16.6 0.3 0.0049 16.6 0.2 1.9 2 0 0 2 2 2 1 zinc-ribbons PHD PF00628.24 EWM21898.1 - 0.033 13.8 4.3 0.074 12.7 3.0 1.7 1 0 0 1 1 1 0 PHD-finger Cullin PF00888.17 EWM21899.1 - 6.7e-10 38.1 0.0 8.6e-10 37.7 0.0 1.0 1 0 0 1 1 1 1 Cullin family AIM24 PF01987.12 EWM21900.1 - 1.5e-52 178.2 4.6 2e-52 177.8 3.2 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DnaJ PF00226.26 EWM21901.1 - 8e-15 54.3 0.1 1.6e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.1 EWM21901.1 - 0.0034 16.7 0.0 0.0076 15.6 0.0 1.6 1 0 0 1 1 1 1 A repeated domain in UCH-protein Methyltransf_23 PF13489.1 EWM21902.1 - 8.6e-06 25.5 0.0 1.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM21902.1 - 0.00013 22.4 0.0 0.00033 21.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM21902.1 - 0.0026 17.3 0.0 0.0038 16.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EWM21902.1 - 0.17 10.5 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) tRNA-synt_1c PF00749.16 EWM21903.1 - 6.7e-95 317.3 0.2 1e-94 316.7 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EWM21903.1 - 1.9e-34 118.8 0.0 5e-34 117.4 0.0 1.8 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain UPF0016 PF01169.14 EWM21904.1 - 4.6e-32 110.0 30.8 2.6e-19 69.1 4.9 3.0 3 0 0 3 3 3 2 Uncharacterized protein family UPF0016 YGGT PF02325.12 EWM21906.1 - 1.1e-14 54.1 5.6 1.5e-14 53.6 3.3 1.7 1 1 0 1 1 1 1 YGGT family NUDIX PF00293.23 EWM21907.1 - 4.5e-13 48.9 0.1 7.8e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.6 EWM21907.1 - 2.6e-06 26.8 6.5 4.9e-06 25.9 4.5 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain NUDIX-like PF09296.6 EWM21907.1 - 4.7e-05 23.6 0.0 8.7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain Ribosomal_S15 PF00312.17 EWM21908.1 - 3.7e-16 58.6 0.4 6.3e-16 57.9 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 Ribosomal_S15 PF00312.17 EWM21909.1 - 3.7e-16 58.6 0.4 6.3e-16 57.9 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 zf-RING_2 PF13639.1 EWM21910.1 - 4.2e-11 42.4 9.0 4.2e-11 42.4 6.3 2.4 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 EWM21910.1 - 6.6e-05 22.8 12.1 0.00015 21.7 6.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EWM21910.1 - 6.6e-05 22.4 9.3 0.0024 17.4 5.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EWM21910.1 - 0.00012 22.1 13.2 0.00066 19.7 5.3 2.7 2 2 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EWM21910.1 - 0.00028 20.5 11.3 0.00035 20.2 5.4 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EWM21910.1 - 0.00034 20.2 7.4 0.00034 20.2 5.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Actin PF00022.14 EWM21911.1 - 1.1e-94 317.0 0.0 1.3e-94 316.9 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EWM21911.1 - 3.5e-05 22.5 0.0 0.099 11.2 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein CDC45 PF02724.9 EWM21913.1 - 4.3e-151 504.0 8.7 8.9e-111 370.8 2.9 2.0 1 1 1 2 2 2 2 CDC45-like protein DHH PF01368.15 EWM21913.1 - 0.00065 19.3 0.0 0.01 15.4 0.0 2.3 1 1 1 2 2 2 1 DHH family LON PF02190.11 EWM21914.1 - 1.5e-12 47.6 0.0 1.8e-11 44.0 0.0 2.0 1 1 0 1 1 1 1 ATP-dependent protease La (LON) domain GSH_synth_ATP PF03917.12 EWM21915.1 - 9.2e-110 366.7 0.0 1.1e-109 366.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EWM21915.1 - 2.6e-30 104.6 0.0 5.6e-30 103.5 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Fasciclin PF02469.17 EWM21916.1 - 3.1e-67 224.4 0.0 3.2e-16 59.4 0.0 6.4 6 0 0 6 6 6 6 Fasciclin domain Methyltransf_16 PF10294.4 EWM21917.1 - 1.7e-30 105.7 0.0 2.3e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EWM21917.1 - 0.0032 17.2 0.0 0.0046 16.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EWM21917.1 - 0.035 13.4 0.1 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.2 EWM21917.1 - 0.038 14.5 0.0 0.07 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain LRR_4 PF12799.2 EWM21918.1 - 2.9e-23 81.0 29.1 0.00041 19.8 0.3 11.6 5 1 5 12 12 12 9 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EWM21918.1 - 6.4e-19 65.8 41.6 0.12 12.5 0.2 16.5 15 2 3 18 18 18 9 Leucine Rich repeat LRR_8 PF13855.1 EWM21918.1 - 7.6e-10 38.4 37.5 0.002 17.8 0.4 7.6 5 3 4 9 9 9 7 Leucine rich repeat LRR_1 PF00560.28 EWM21918.1 - 9.7e-05 21.8 37.8 5.6 7.3 0.0 13.7 12 4 3 15 15 15 4 Leucine Rich Repeat LRR_9 PF14580.1 EWM21918.1 - 0.097 12.2 7.4 2.6 7.5 0.2 3.9 3 1 1 4 4 4 0 Leucine-rich repeat DUF3645 PF12359.3 EWM21919.1 - 1.8e-18 65.3 0.1 4.2e-18 64.1 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) DUF3638 PF12340.3 EWM21919.1 - 1.8e-17 63.0 0.0 8.9e-17 60.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3638) EF-hand_7 PF13499.1 EWM21919.1 - 2.4e-12 46.7 2.0 2.8e-06 27.3 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 EWM21919.1 - 3.7e-10 38.3 1.7 5.1e-05 22.2 0.1 4.1 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 EWM21919.1 - 1.5e-09 36.9 4.4 0.012 15.4 0.0 4.1 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 EWM21919.1 - 4.1e-08 32.7 0.8 2.5e-06 26.9 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain pair DUF946 PF06101.6 EWM21919.1 - 0.00033 18.7 0.0 0.00064 17.8 0.0 1.4 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) EF-hand_5 PF13202.1 EWM21919.1 - 0.0019 17.4 0.2 0.0019 17.4 0.1 2.3 2 0 0 2 2 2 1 EF hand Caldesmon PF02029.10 EWM21919.1 - 0.044 12.1 6.4 0.068 11.5 4.5 1.2 1 0 0 1 1 1 0 Caldesmon Ycf1 PF05758.7 EWM21919.1 - 0.55 7.8 1.8 0.81 7.3 1.2 1.1 1 0 0 1 1 1 0 Ycf1 DUF4557 PF15101.1 EWM21919.1 - 0.62 9.8 2.7 1.2 8.9 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) CENP-T PF15511.1 EWM21919.1 - 1.1 8.4 9.0 1.8 7.6 6.3 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T PAT1 PF09770.4 EWM21919.1 - 5.1 5.1 9.4 8 4.5 6.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 EWM21919.1 - 7.1 4.6 4.8 11 4.1 3.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Peptidase_M1 PF01433.15 EWM21920.1 - 1.5e-136 455.5 0.0 2e-136 455.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EWM21920.1 - 1e-63 215.5 0.0 1.5e-63 215.0 0.0 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EWM21920.1 - 5.2e-22 78.2 0.7 9.8e-22 77.3 0.5 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily SprT-like PF10263.4 EWM21920.1 - 0.024 14.2 0.0 0.073 12.7 0.0 1.7 2 0 0 2 2 2 0 SprT-like family UAA PF08449.6 EWM21922.1 - 4.3e-62 209.7 10.2 7.4e-62 208.9 7.1 1.3 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EWM21922.1 - 1.3e-05 25.2 10.1 1.3e-05 25.2 7.0 3.2 2 1 1 3 3 3 1 EamA-like transporter family TPT PF03151.11 EWM21922.1 - 1.6e-05 24.6 8.6 1.6e-05 24.6 6.0 2.9 2 1 0 2 2 2 1 Triose-phosphate Transporter family UPF0546 PF10639.4 EWM21922.1 - 3.3 7.5 7.9 5.1 6.9 1.2 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 DUF4391 PF14335.1 EWM21923.1 - 0.055 12.8 0.4 0.15 11.4 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4391) UPRTase PF14681.1 EWM21924.1 - 1.3e-61 207.4 0.0 1.5e-61 207.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EWM21924.1 - 2.2e-06 27.3 0.1 3.5e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PFK PF00365.15 EWM21924.1 - 0.1 11.5 0.1 0.15 11.0 0.1 1.2 1 0 0 1 1 1 0 Phosphofructokinase FHA PF00498.21 EWM21926.1 - 1.5e-10 41.0 0.0 2.6e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 EWM21926.1 - 1.6e-06 27.8 15.3 5.6e-06 26.0 6.6 2.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EWM21926.1 - 1.8e-06 27.5 8.5 1.8e-06 27.5 5.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EWM21926.1 - 1.1e-05 25.0 9.2 1.1e-05 25.0 6.4 2.6 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EWM21926.1 - 4e-05 23.5 9.3 4e-05 23.5 6.5 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EWM21926.1 - 0.0012 18.7 9.3 0.0012 18.7 6.5 2.9 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EWM21926.1 - 0.0084 15.7 8.3 0.0084 15.7 5.8 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EWM21926.1 - 0.014 15.0 5.4 0.014 15.0 3.7 2.4 1 1 1 2 2 2 0 RING-type zinc-finger Tudor-knot PF11717.3 EWM21927.1 - 1.1e-05 24.9 2.8 1.1e-05 24.9 1.9 1.9 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Agenet PF05641.7 EWM21927.1 - 9.4e-05 22.4 2.6 0.094 12.8 0.1 3.2 3 0 0 3 3 3 2 Agenet domain F-box-like PF12937.2 EWM21927.1 - 0.00075 19.1 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EWM21927.1 - 0.0044 16.6 0.0 0.0097 15.5 0.0 1.6 1 0 0 1 1 1 1 F-box domain Cullin PF00888.17 EWM21928.1 - 3.7e-75 253.6 0.0 7.4e-43 146.9 0.0 2.1 2 0 0 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.4 EWM21928.1 - 2.2e-09 36.9 0.0 3.8e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Cullin protein neddylation domain HSA PF07529.8 EWM21929.1 - 1.7e-16 59.7 7.7 1.7e-16 59.7 5.3 2.3 2 1 1 3 3 3 1 HSA DBINO PF13892.1 EWM21929.1 - 5.3e-05 23.2 11.5 0.00078 19.5 8.0 2.2 1 1 0 1 1 1 1 DNA-binding domain DUF3611 PF12263.3 EWM21930.1 - 1e-32 113.0 8.2 1.5e-32 112.4 5.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3611) NifU PF01106.12 EWM21931.1 - 2.7e-29 100.7 1.1 3.5e-25 87.5 0.3 2.2 2 0 0 2 2 2 2 NifU-like domain Sds3 PF08598.6 EWM21932.1 - 0.00019 21.0 2.6 0.00028 20.4 1.8 1.4 1 0 0 1 1 1 1 Sds3-like ECH PF00378.15 EWM21937.1 - 2e-33 115.5 0.0 2.5e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family MitMem_reg PF13012.1 EWM21938.1 - 3.3e-13 49.7 0.0 5.2e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EWM21938.1 - 1.7e-12 47.0 0.0 2.8e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease JAB PF01398.16 EWM21939.1 - 1.6e-24 85.8 0.3 2.3e-24 85.3 0.2 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EWM21939.1 - 3.5e-07 29.7 0.2 6.9e-07 28.7 0.1 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain SNF2_N PF00176.18 EWM21940.1 - 8.2e-25 87.1 0.1 1.1e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EWM21940.1 - 2.4e-16 59.3 0.1 6.3e-16 58.0 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EWM21940.1 - 0.012 14.4 0.0 0.24 10.1 0.0 2.0 2 0 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 Activator_LAG-3 PF11498.3 EWM21941.1 - 0.071 11.8 58.6 0.088 11.5 40.6 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 YfhO PF09586.5 EWM21941.1 - 2.3 6.1 6.8 2.6 5.9 4.7 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF775 PF05603.7 EWM21941.1 - 3.1 7.2 11.5 4.1 6.8 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF342 PF03961.8 EWM21941.1 - 9.4 4.5 8.4 11 4.2 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TFIIA PF03153.8 EWM21941.1 - 9.4 6.0 29.0 12 5.6 20.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DIM1 PF02966.11 EWM21942.1 - 3.3e-66 220.8 0.8 4e-66 220.5 0.5 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 DUF179 PF02622.10 EWM21943.1 - 2e-18 66.5 0.0 5.1e-17 61.9 0.0 2.2 1 1 0 1 1 1 1 Uncharacterized ACR, COG1678 RINGv PF12906.2 EWM21943.1 - 1e-10 41.4 5.5 1.9e-10 40.5 3.8 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EWM21943.1 - 0.096 12.5 5.7 0.18 11.6 3.9 1.5 1 0 0 1 1 1 0 Ring finger domain PHD PF00628.24 EWM21943.1 - 0.33 10.6 2.2 0.53 10.0 1.5 1.3 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_3 PF13920.1 EWM21943.1 - 0.35 10.5 4.4 0.63 9.7 3.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ABC2_membrane PF01061.19 EWM21944.1 - 1.9e-39 135.0 12.9 1.9e-39 135.0 9.0 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 EWM21944.1 - 5.7e-24 84.9 0.0 9.2e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EWM21944.1 - 6.4e-09 36.1 0.0 7e-08 32.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain ABC2_membrane_2 PF12679.2 EWM21944.1 - 2.3e-05 23.4 10.3 2.5e-05 23.3 6.5 1.6 1 1 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane_3 PF12698.2 EWM21944.1 - 0.00013 21.1 18.5 0.0002 20.5 12.9 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_29 PF13555.1 EWM21944.1 - 0.00013 21.4 0.4 0.00028 20.3 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 EWM21944.1 - 0.00075 18.7 0.1 1 8.5 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC2_membrane_4 PF12730.2 EWM21944.1 - 0.001 18.3 9.3 0.001 18.3 6.5 1.8 3 0 0 3 3 3 1 ABC-2 family transporter protein AAA_16 PF13191.1 EWM21944.1 - 0.0016 18.4 0.1 0.0065 16.4 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EWM21944.1 - 0.0026 16.9 0.3 0.0047 16.1 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_15 PF13175.1 EWM21944.1 - 0.014 14.4 0.0 0.087 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain MCM PF00493.18 EWM21944.1 - 0.036 12.8 0.0 0.069 11.9 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family SbcCD_C PF13558.1 EWM21944.1 - 0.087 12.7 0.1 0.44 10.4 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 EWM21944.1 - 0.12 12.5 0.0 0.72 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EWM21944.1 - 0.15 12.3 0.1 0.24 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain HALZ PF02183.13 EWM21945.1 - 1.4e-05 24.7 12.8 0.0058 16.3 0.3 4.8 4 0 0 4 4 4 3 Homeobox associated leucine zipper HAUS5 PF14817.1 EWM21945.1 - 1.8e-05 23.5 5.3 1.8e-05 23.5 3.7 2.9 1 1 1 3 3 3 1 HAUS augmin-like complex subunit 5 Mnd1 PF03962.10 EWM21945.1 - 0.0057 16.3 6.1 0.0057 16.3 4.2 3.4 2 1 1 3 3 3 1 Mnd1 family Reo_sigmaC PF04582.7 EWM21945.1 - 0.019 14.1 5.5 0.35 10.0 1.5 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Phage_GP20 PF06810.6 EWM21945.1 - 0.053 12.9 0.5 0.053 12.9 0.4 4.4 2 1 3 5 5 5 0 Phage minor structural protein GP20 Toxin_44 PF15523.1 EWM21945.1 - 0.17 11.7 6.0 0.19 11.5 1.6 2.9 1 1 0 2 2 2 0 Putative toxin 44 DUF3584 PF12128.3 EWM21945.1 - 0.22 8.8 39.5 0.3 8.3 14.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Sipho_Gp157 PF05565.6 EWM21945.1 - 1.1 8.8 26.8 0.79 9.2 0.4 4.2 2 1 1 3 3 3 0 Siphovirus Gp157 IncA PF04156.9 EWM21945.1 - 1.1 8.7 37.9 1.5e+04 -9.8 26.3 3.3 1 1 0 1 1 0 0 IncA protein TPR_MLP1_2 PF07926.7 EWM21945.1 - 1.4 8.6 45.1 8.6 6.1 16.5 4.0 2 2 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2353 PF09789.4 EWM21945.1 - 3.5 6.7 31.0 0.02 14.1 10.2 2.5 1 1 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) NPV_P10 PF05531.7 EWM21945.1 - 8.4 6.7 9.3 1.2 9.4 0.3 3.6 3 1 2 5 5 5 0 Nucleopolyhedrovirus P10 protein Metallophos PF00149.23 EWM21946.1 - 9.2e-10 38.2 2.0 1.6e-09 37.4 1.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EWM21946.1 - 8e-09 35.5 0.1 1.2e-08 34.9 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain IncA PF04156.9 EWM21947.1 - 0.0049 16.4 23.8 0.008 15.7 7.4 2.2 1 1 1 2 2 2 2 IncA protein GAS PF13851.1 EWM21947.1 - 0.046 12.9 19.5 0.094 11.8 4.6 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF745 PF05335.8 EWM21947.1 - 2.5 7.5 21.3 3.9 6.9 4.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) CENP-Q PF13094.1 EWM21947.1 - 3.7 7.5 21.9 12 5.9 4.3 2.8 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit AAA_13 PF13166.1 EWM21947.1 - 4.7 5.5 12.9 5.8 5.2 8.9 1.2 1 0 0 1 1 1 0 AAA domain DUF4446 PF14584.1 EWM21947.1 - 4.8 6.9 14.8 1.4 8.7 0.1 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) Atg14 PF10186.4 EWM21947.1 - 5.5 5.8 23.1 0.32 9.8 7.1 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 FliJ PF02050.11 EWM21947.1 - 6.7 6.7 26.1 1.9 8.5 7.1 2.8 2 1 2 4 4 4 0 Flagellar FliJ protein Chloroa_b-bind PF00504.16 EWM21948.1 - 6.6e-36 123.9 0.0 9.5e-36 123.3 0.0 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Shadoo PF14999.1 EWM21948.1 - 0.041 13.7 0.4 0.093 12.5 0.1 1.7 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective DUF2059 PF09832.4 EWM21949.1 - 9.1e-07 28.8 0.0 2e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2059) zf-C4H2 PF10146.4 EWM21950.1 - 0.00012 22.1 0.4 0.00035 20.6 0.3 1.8 1 0 0 1 1 1 1 Zinc finger-containing protein HAUS-augmin3 PF14932.1 EWM21950.1 - 0.044 12.9 10.7 0.093 11.8 7.4 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Ax_dynein_light PF10211.4 EWM21950.1 - 0.08 12.7 12.8 0.2 11.4 8.8 1.7 1 0 0 1 1 1 0 Axonemal dynein light chain IncA PF04156.9 EWM21950.1 - 0.18 11.4 16.1 0.049 13.2 8.9 1.7 2 0 0 2 2 2 0 IncA protein DUF1664 PF07889.7 EWM21950.1 - 0.72 9.6 4.0 1.7 8.4 2.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Macoilin PF09726.4 EWM21950.1 - 2.5 6.2 9.3 3.4 5.8 6.5 1.1 1 0 0 1 1 1 0 Transmembrane protein ABC_tran PF00005.22 EWM21951.1 - 1.3e-44 151.8 0.0 8.3e-21 74.7 0.0 3.2 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 EWM21951.1 - 2.5e-20 73.6 0.2 5.5e-05 23.2 0.0 4.3 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 EWM21951.1 - 4e-10 39.2 0.0 0.032 13.4 0.0 3.8 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EWM21951.1 - 2.8e-09 37.8 1.4 0.0038 18.0 0.0 4.1 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.1 EWM21951.1 - 1.1e-08 34.4 0.1 0.00039 19.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EWM21951.1 - 1.6e-08 35.1 10.7 0.0001 22.6 0.0 3.7 4 0 0 4 4 3 2 AAA domain NACHT PF05729.7 EWM21951.1 - 5.2e-07 29.4 0.0 0.034 13.8 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_10 PF12846.2 EWM21951.1 - 6.5e-07 29.0 0.0 0.077 12.4 0.0 3.3 3 0 0 3 3 3 2 AAA-like domain AAA_22 PF13401.1 EWM21951.1 - 1.1e-06 28.7 0.2 0.14 12.3 0.0 3.4 2 1 0 2 2 2 2 AAA domain ABC_tran_2 PF12848.2 EWM21951.1 - 1.7e-06 27.7 8.9 1.7e-06 27.7 6.2 2.9 3 0 0 3 3 2 1 ABC transporter AAA PF00004.24 EWM21951.1 - 4.4e-06 26.9 0.1 0.23 11.6 0.0 3.5 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EWM21951.1 - 8.9e-06 24.9 0.0 0.03 13.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MobB PF03205.9 EWM21951.1 - 1.6e-05 24.6 0.2 0.2 11.3 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EWM21951.1 - 2.3e-05 24.4 2.4 0.055 13.4 0.0 3.5 2 2 1 3 3 3 2 AAA ATPase domain AAA_28 PF13521.1 EWM21951.1 - 3.1e-05 24.0 3.4 0.075 12.9 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.1 EWM21951.1 - 3.4e-05 23.7 0.1 0.13 12.0 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.1 EWM21951.1 - 4.7e-05 22.8 0.0 0.046 13.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_13 PF13166.1 EWM21951.1 - 9.1e-05 21.1 8.8 0.0011 17.6 0.0 3.5 4 0 0 4 4 3 1 AAA domain AAA_14 PF13173.1 EWM21951.1 - 0.00012 22.0 0.1 1.3 8.8 0.0 3.7 5 0 0 5 5 2 2 AAA domain AAA_18 PF13238.1 EWM21951.1 - 0.00014 22.1 1.4 0.12 12.6 0.0 4.1 4 1 0 4 4 4 1 AAA domain RNA_helicase PF00910.17 EWM21951.1 - 0.00018 21.6 0.0 0.49 10.6 0.0 2.8 2 0 0 2 2 2 1 RNA helicase SbcCD_C PF13558.1 EWM21951.1 - 0.00032 20.5 0.3 0.16 11.8 0.1 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Arch_ATPase PF01637.13 EWM21951.1 - 0.00036 20.3 0.3 1.8 8.2 0.0 3.2 3 0 0 3 3 3 2 Archaeal ATPase cobW PF02492.14 EWM21951.1 - 0.001 18.5 0.0 1 8.7 0.0 2.6 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 EWM21951.1 - 0.0012 19.3 0.0 0.35 11.3 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_15 PF13175.1 EWM21951.1 - 0.0012 18.0 2.7 0.36 9.8 0.0 3.5 4 1 0 4 4 4 1 AAA ATPase domain AAA_19 PF13245.1 EWM21951.1 - 0.0019 17.8 0.1 1.7 8.4 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain MMR_HSR1 PF01926.18 EWM21951.1 - 0.0021 17.9 0.0 0.21 11.5 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_5 PF07728.9 EWM21951.1 - 0.0041 16.8 0.8 0.38 10.4 0.1 2.9 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 EWM21951.1 - 0.0044 16.7 0.3 0.99 9.0 0.1 2.6 2 0 0 2 2 2 1 NTPase T2SE PF00437.15 EWM21951.1 - 0.0077 15.1 0.0 1 8.2 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Mg_chelatase PF01078.16 EWM21951.1 - 0.011 14.8 0.1 5.8 6.0 0.0 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI PduV-EutP PF10662.4 EWM21951.1 - 0.013 15.0 0.0 4.2 6.8 0.0 2.7 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.17 EWM21951.1 - 0.014 14.2 0.0 5.5 5.7 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.1 EWM21951.1 - 0.021 14.4 4.8 1.8 8.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain ResIII PF04851.10 EWM21951.1 - 0.031 14.1 0.3 50 3.6 0.8 3.4 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit SRP54 PF00448.17 EWM21951.1 - 0.038 13.4 0.1 4.7 6.6 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ATP-synt_ab PF00006.20 EWM21951.1 - 0.038 13.4 0.0 1.9 7.9 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_ATPase PF09818.4 EWM21951.1 - 0.039 12.5 0.0 12 4.3 0.0 3.2 4 0 0 4 4 4 0 Predicted ATPase of the ABC class DUF3987 PF13148.1 EWM21951.1 - 0.045 12.3 0.0 0.045 12.3 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3987) MutS_V PF00488.16 EWM21951.1 - 0.076 12.4 0.0 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 MutS domain V Dynamin_N PF00350.18 EWM21951.1 - 0.12 12.2 1.6 7.9 6.2 0.0 3.1 3 0 0 3 3 3 0 Dynamin family ATP_bind_1 PF03029.12 EWM21951.1 - 0.12 11.9 0.1 3.5 7.1 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Pox_A32 PF04665.7 EWM21951.1 - 0.15 11.3 0.1 18 4.5 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein SUZ PF12752.2 EWM21951.1 - 0.67 10.5 9.9 5.6 7.5 0.4 2.9 2 1 0 2 2 2 0 SUZ domain SpoU_methylase PF00588.14 EWM21952.1 - 2.4e-28 98.8 0.1 4.7e-28 97.8 0.0 1.5 2 0 0 2 2 2 1 SpoU rRNA Methylase family Mito_carr PF00153.22 EWM21953.1 - 2.5e-50 168.1 2.3 1.4e-23 82.3 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein PRK PF00485.13 EWM21954.1 - 1.4e-69 233.5 0.0 2.4e-69 232.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 EWM21954.1 - 0.038 14.8 0.5 0.15 12.8 0.3 2.1 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EWM21954.1 - 0.049 13.9 0.1 0.17 12.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain TLD PF07534.11 EWM21955.1 - 1.3e-06 28.4 0.0 1.7e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 TLD PH PF00169.24 EWM21958.1 - 0.0037 17.4 0.0 0.0095 16.1 0.0 1.7 1 0 0 1 1 1 1 PH domain Mito_carr PF00153.22 EWM21959.1 - 0.00049 19.7 0.9 0.00096 18.8 0.6 1.6 1 1 0 1 1 1 1 Mitochondrial carrier protein Ribosomal_60s PF00428.14 EWM21960.1 - 0.58 10.5 5.7 0.65 10.4 3.0 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein COX6B PF02297.12 EWM21962.1 - 0.0022 17.9 0.3 0.0036 17.2 0.2 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb COX17 PF05051.8 EWM21962.1 - 0.06 13.3 0.3 0.74 9.8 0.1 2.1 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) CHCH PF06747.8 EWM21962.1 - 0.075 12.9 3.1 0.81 9.6 0.4 2.2 2 0 0 2 2 2 0 CHCH domain UAF_Rrn10 PF05234.6 EWM21964.1 - 0.056 13.4 0.0 0.083 12.9 0.0 1.2 1 0 0 1 1 1 0 UAF complex subunit Rrn10 Na_H_Exchanger PF00999.16 EWM21966.1 - 1.6e-56 191.5 42.6 2e-56 191.1 29.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Glycos_transf_1 PF00534.15 EWM21967.1 - 1.2e-18 67.0 0.0 8.8e-17 61.0 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EWM21967.1 - 2.6e-08 34.0 0.0 8.3e-08 32.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EWM21967.1 - 5.2e-07 29.8 0.0 1.1e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF1495 PF07381.6 EWM21967.1 - 0.13 11.9 0.2 1 9.0 0.1 2.2 2 0 0 2 2 2 0 Winged helix DNA-binding domain (DUF1495) GTP_EFTU PF00009.22 EWM21968.1 - 5.7e-41 140.0 0.0 9e-41 139.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EWM21968.1 - 3e-10 40.1 0.0 6.4e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EWM21968.1 - 0.00022 21.2 1.4 0.0006 19.8 1.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EWM21968.1 - 0.0058 16.5 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EWM21968.1 - 0.014 15.8 0.0 0.15 12.6 0.0 2.2 1 1 0 1 1 1 0 Miro-like protein GTP_EFTU_D4 PF14578.1 EWM21968.1 - 0.081 12.5 0.8 0.24 11.0 0.5 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 4 PBP1_TM PF14812.1 EWM21968.1 - 1.8 8.9 6.4 3.5 7.9 4.5 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HIT PF01230.18 EWM21969.1 - 1.4e-25 89.6 0.1 2.3e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EWM21969.1 - 4.3e-22 78.5 0.0 7.4e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GST_N_3 PF13417.1 EWM21969.1 - 1.7e-09 37.7 0.0 2.9e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EWM21969.1 - 1.3e-06 28.4 0.0 2.4e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EWM21969.1 - 5.2e-06 26.3 0.0 1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EWM21969.1 - 0.00014 21.6 0.1 0.00031 20.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EWM21969.1 - 0.00014 22.2 0.1 0.0005 20.4 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EWM21969.1 - 0.0004 20.3 0.1 0.00077 19.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Na_H_Exchanger PF00999.16 EWM21970.1 - 1.8e-57 194.6 43.3 2.2e-57 194.3 30.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family FA_desaturase PF00487.19 EWM21971.1 - 0.066 12.6 0.0 0.078 12.4 0.0 1.1 1 0 0 1 1 1 0 Fatty acid desaturase GPI2 PF06432.6 EWM21971.1 - 0.54 9.5 2.5 0.69 9.2 1.7 1.1 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase CbiQ PF02361.11 EWM21971.1 - 0.56 9.7 3.1 0.71 9.3 2.1 1.1 1 0 0 1 1 1 0 Cobalt transport protein DUF3407 PF11887.3 EWM21973.1 - 0.026 13.7 0.1 0.19 10.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3407) E1_DerP2_DerF2 PF02221.10 EWM21974.1 - 2.8e-09 37.3 0.0 4.1e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 ML domain OpgC_C PF10129.4 EWM21977.1 - 0.045 12.4 0.0 0.051 12.2 0.0 1.0 1 0 0 1 1 1 0 OpgC protein Sigma54_AID PF00309.15 EWM21977.1 - 0.11 11.9 1.6 0.24 10.8 1.1 1.6 1 0 0 1 1 1 0 Sigma-54 factor, Activator interacting domain (AID) API5 PF05918.6 EWM21978.1 - 6.5 5.1 5.5 9.3 4.6 3.8 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Ammonium_transp PF00909.16 EWM21983.1 - 2.1e-16 59.4 0.6 2.2e-16 59.3 0.4 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family RDD PF06271.7 EWM21983.1 - 0.25 11.2 3.1 0.37 10.6 2.1 1.2 1 0 0 1 1 1 0 RDD family PT PF04886.7 EWM21985.1 - 1.9e-08 33.4 146.8 0.072 12.4 20.3 5.5 1 1 3 4 4 4 3 PT repeat ABC_membrane PF00664.18 EWM21991.1 - 1e-24 87.4 1.1 1.5e-24 86.8 0.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_membrane PF00664.18 EWM21992.1 - 7.5e-10 38.6 0.5 1.3e-09 37.8 0.4 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region NUDIX PF00293.23 EWM21993.1 - 2e-08 33.9 0.5 2.8e-08 33.4 0.0 1.5 2 0 0 2 2 2 1 NUDIX domain NUDIX PF00293.23 EWM21994.1 - 1.4e-08 34.4 0.1 1.7e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain CS PF04969.11 EWM21996.1 - 3.8e-05 24.1 0.0 6.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 CS domain CDC37_N PF03234.9 EWM21996.1 - 0.0017 18.6 5.3 0.0026 18.0 3.7 1.2 1 0 0 1 1 1 1 Cdc37 N terminal kinase binding Rotamase_3 PF13616.1 EWM21998.1 - 9.8e-13 48.4 0.0 1.3e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 EWM21998.1 - 4e-09 37.0 0.0 6e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rhodanese PF00581.15 EWM21999.1 - 3.4e-14 53.1 0.0 4.9e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain PepSY_TM_2 PF13703.1 EWM22002.1 - 0.071 13.2 0.2 0.18 11.9 0.1 1.8 1 0 0 1 1 1 0 PepSY-associated TM helix Ste5 PF11610.3 EWM22005.1 - 0.014 14.8 0.6 0.032 13.7 0.4 1.5 1 0 0 1 1 1 0 Scaffold protein Ste5-Fus5 binding region V_ATPase_I PF01496.14 EWM22007.1 - 3e-41 141.1 0.1 2.7e-25 88.4 0.0 2.0 2 0 0 2 2 2 2 V-type ATPase 116kDa subunit family V_ATPase_I PF01496.14 EWM22008.1 - 5.6e-11 41.0 0.0 5.6e-11 41.0 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Cep57_CLD PF14073.1 EWM22008.1 - 0.084 12.6 0.0 0.099 12.4 0.0 1.1 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 LAGLIDADG_WhiA PF14527.1 EWM22008.1 - 0.14 12.0 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain Chloroa_b-bind PF00504.16 EWM22009.1 - 2.2e-23 83.2 0.0 3.5e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Fasciclin PF02469.17 EWM22009.1 - 7.7e-19 67.9 0.0 1.2e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain DUF3708 PF12501.3 EWM22010.1 - 0.041 13.7 0.1 0.078 12.8 0.1 1.4 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter Ank_2 PF12796.2 EWM22011.1 - 4.9e-46 154.9 9.4 3e-15 56.3 0.2 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EWM22011.1 - 2.8e-22 77.3 13.3 2.6e-07 30.0 0.0 7.0 7 2 0 7 7 7 4 Ankyrin repeat Ank_3 PF13606.1 EWM22011.1 - 3.8e-21 73.0 1.7 4.1e-05 23.4 0.0 5.5 5 2 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 EWM22011.1 - 9.2e-18 63.8 11.3 1.9e-06 27.9 0.1 5.6 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EWM22011.1 - 1.6e-14 53.9 8.5 1.6e-06 28.4 0.1 4.7 4 1 1 5 5 5 3 Ankyrin repeats (many copies) UPF0061 PF02696.9 EWM22014.1 - 3.3e-12 45.4 0.0 3.3e-12 45.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Exo_endo_phos PF03372.18 EWM22015.1 - 1.4e-10 41.5 0.0 1.9e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PGAP1 PF07819.8 EWM22016.1 - 2.5e-07 30.5 0.0 4e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EWM22016.1 - 3.7e-06 26.7 1.3 8.2e-06 25.6 0.9 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EWM22016.1 - 0.00017 21.5 6.8 0.00055 19.8 4.7 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EWM22016.1 - 0.015 14.9 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) DUF676 PF05057.9 EWM22016.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Putative serine esterase (DUF676) NADH_4Fe-4S PF10589.4 EWM22017.1 - 1.4 8.1 4.0 2.4 7.3 2.8 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region UPF0061 PF02696.9 EWM22018.1 - 1.1e-18 66.7 0.0 1.4e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family RRM_1 PF00076.17 EWM22019.1 - 5.1e-10 38.8 0.0 8.1e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM22019.1 - 4e-07 29.8 0.0 7e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM22019.1 - 0.0015 18.3 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EWM22019.1 - 0.075 12.8 0.1 0.17 11.7 0.0 1.6 2 0 0 2 2 2 0 RNA binding motif 4HBT_3 PF13622.1 EWM22020.1 - 1.9e-25 90.0 0.4 2.7e-25 89.5 0.3 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily EF-hand_7 PF13499.1 EWM22021.1 - 3.1e-09 36.8 1.6 4.4e-09 36.3 0.9 1.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 EWM22021.1 - 8.4e-09 34.9 0.6 1.3e-08 34.3 0.4 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EWM22021.1 - 1.8e-06 26.8 4.4 0.0099 15.1 1.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EWM22021.1 - 6.9e-05 22.4 2.8 0.035 13.9 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain p25-alpha PF05517.7 EWM22021.1 - 0.049 13.8 0.0 0.06 13.6 0.0 1.1 1 0 0 1 1 1 0 p25-alpha HSP20 PF00011.16 EWM22022.1 - 4.1e-23 81.1 0.4 4.8e-23 80.9 0.3 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family EzrA PF06160.7 EWM22023.1 - 0.0021 16.3 5.7 0.0028 15.9 4.0 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA V-SNARE PF05008.10 EWM22023.1 - 0.031 14.4 3.5 0.031 14.4 2.4 2.4 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF724 PF05266.9 EWM22023.1 - 0.091 12.3 6.6 0.024 14.2 2.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Fmp27_WPPW PF10359.4 EWM22023.1 - 0.14 10.5 7.2 0.18 10.1 5.0 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Spc7 PF08317.6 EWM22023.1 - 0.17 10.5 8.3 0.24 10.0 5.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein CR6_interact PF10147.4 EWM22023.1 - 0.18 11.0 8.6 0.26 10.5 5.9 1.2 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 APG6 PF04111.7 EWM22023.1 - 0.22 10.5 6.4 0.28 10.1 4.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Sds3 PF08598.6 EWM22023.1 - 0.44 10.0 6.5 0.73 9.3 4.5 1.4 1 0 0 1 1 1 0 Sds3-like ADIP PF11559.3 EWM22023.1 - 0.72 9.7 12.0 2.1 8.2 8.1 1.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 EWM22023.1 - 1.2 8.7 12.2 1.8 8.1 8.5 1.2 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EWM22023.1 - 1.3 6.8 4.2 1.5 6.5 2.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.1 EWM22023.1 - 1.3 9.2 4.4 1.8 8.8 3.1 1.4 1 0 0 1 1 1 0 AAA domain DUF4140 PF13600.1 EWM22023.1 - 1.6 9.1 11.0 2.6 8.5 2.2 2.7 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) AAA_2 PF07724.9 EWM22024.1 - 6.2e-52 175.9 0.0 1.2e-51 175.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EWM22024.1 - 2.4e-20 72.2 0.4 7.2e-20 70.6 0.3 1.9 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EWM22024.1 - 2.2e-12 46.8 0.0 9.1e-12 44.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 EWM22024.1 - 3.1e-11 43.5 0.0 6.8e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EWM22024.1 - 4.3e-07 29.5 0.2 8.8e-07 28.5 0.0 1.6 2 0 0 2 2 1 1 Sigma-54 interaction domain AAA_16 PF13191.1 EWM22024.1 - 1.6e-06 28.2 0.3 1.3e-05 25.2 0.0 2.3 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EWM22024.1 - 0.00013 22.0 0.0 0.00055 20.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EWM22024.1 - 0.00017 21.4 0.0 0.00062 19.6 0.0 2.0 2 0 0 2 2 1 1 AAA domain DNA_pol3_delta2 PF13177.1 EWM22024.1 - 0.0002 21.0 0.0 0.00054 19.6 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase III, delta subunit IstB_IS21 PF01695.12 EWM22024.1 - 0.00034 20.0 0.0 0.00082 18.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 EWM22024.1 - 0.00044 21.0 0.0 0.0012 19.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.7 EWM22024.1 - 0.00088 18.4 0.0 0.0017 17.5 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin DUF87 PF01935.12 EWM22024.1 - 0.0013 18.5 0.0 0.0029 17.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_10 PF12846.2 EWM22024.1 - 0.0028 17.1 0.0 0.0036 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_18 PF13238.1 EWM22024.1 - 0.0033 17.7 0.0 0.0097 16.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EWM22024.1 - 0.0038 16.1 0.0 0.0064 15.4 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein RNA_helicase PF00910.17 EWM22024.1 - 0.0071 16.5 0.1 0.025 14.7 0.0 1.9 2 0 0 2 2 2 1 RNA helicase ABC_tran PF00005.22 EWM22024.1 - 0.0072 16.6 0.0 0.014 15.6 0.0 1.7 1 1 0 1 1 1 1 ABC transporter DUF815 PF05673.8 EWM22024.1 - 0.014 14.3 0.0 0.024 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 EWM22024.1 - 0.015 14.4 0.1 0.24 10.5 0.1 2.4 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.1 EWM22024.1 - 0.017 15.4 0.0 0.033 14.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EWM22024.1 - 0.018 14.1 0.0 0.045 12.8 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Arch_ATPase PF01637.13 EWM22024.1 - 0.018 14.7 0.0 0.71 9.5 0.0 2.3 1 1 0 2 2 2 0 Archaeal ATPase AAA_33 PF13671.1 EWM22024.1 - 0.021 14.7 0.0 0.066 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EWM22024.1 - 0.046 12.9 0.0 0.095 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Torsin PF06309.6 EWM22024.1 - 0.058 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Torsin MobB PF03205.9 EWM22024.1 - 0.095 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Bac_DnaA_C PF08299.6 EWM22024.1 - 0.11 12.3 0.0 21 5.0 0.0 2.7 2 0 0 2 2 2 0 Bacterial dnaA protein helix-turn-helix AAA_PrkA PF08298.6 EWM22024.1 - 0.12 11.0 0.0 1.9 7.0 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain Ser_hydrolase PF06821.8 EWM22025.1 - 3.2e-10 39.8 0.0 4.3e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_5 PF12695.2 EWM22025.1 - 3.9e-09 36.4 0.1 7.1e-09 35.5 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EWM22025.1 - 5.8e-07 29.6 1.3 2.8e-06 27.3 0.9 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EWM22025.1 - 0.0027 17.2 0.2 0.069 12.7 0.1 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF1057 PF06342.7 EWM22025.1 - 0.0031 16.3 0.0 0.0044 15.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_4 PF08386.5 EWM22025.1 - 0.039 13.8 0.0 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 TAP-like protein Ndr PF03096.9 EWM22025.1 - 0.081 11.3 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Ndr family Polysacc_deac_1 PF01522.16 EWM22028.1 - 8.4e-10 38.3 0.0 1.4e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase PT PF04886.7 EWM22030.1 - 0.035 13.4 32.4 1.3 8.4 3.7 4.5 3 0 0 3 3 3 0 PT repeat PT PF04886.7 EWM22031.1 - 0.031 13.5 32.4 1.2 8.4 3.7 4.6 3 0 0 3 3 3 0 PT repeat Thioredoxin PF00085.15 EWM22032.1 - 2.8e-58 194.0 0.0 2e-30 104.5 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 EWM22032.1 - 1.2e-24 87.1 0.0 6.9e-16 58.5 0.0 3.5 3 1 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EWM22032.1 - 3e-16 59.5 0.7 2.6e-09 37.2 0.0 4.1 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EWM22032.1 - 1.3e-15 57.2 0.0 1.9e-08 34.2 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 EWM22032.1 - 1.9e-06 27.8 0.0 0.04 14.0 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 EWM22032.1 - 3.1e-05 23.6 0.1 0.018 14.7 0.0 3.1 3 1 0 3 3 3 2 AhpC/TSA family Thioredoxin PF00085.15 EWM22033.1 - 1.4e-25 88.9 0.0 2.5e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.1 EWM22033.1 - 1.1e-18 67.6 0.1 3.7e-16 59.4 0.0 2.8 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EWM22033.1 - 0.00011 22.2 0.0 0.00032 20.6 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EWM22033.1 - 0.00021 21.4 0.3 0.05 13.7 0.2 2.7 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EWM22033.1 - 0.084 13.0 0.0 0.37 10.9 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin-like TauE PF01925.14 EWM22034.1 - 6.9e-17 61.6 18.7 6.9e-17 61.6 12.9 1.9 1 1 1 2 2 2 2 Sulfite exporter TauE/SafE DUF543 PF04418.7 EWM22034.1 - 5.9 6.9 7.6 5 7.1 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF543) Ribosomal_L32e PF01655.13 EWM22035.1 - 3.2e-45 152.6 1.1 3.9e-45 152.4 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Exo_endo_phos PF03372.18 EWM22036.1 - 2.5e-10 40.7 0.0 3.7e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Myc_target_1 PF15179.1 EWM22036.1 - 0.096 12.2 0.2 2.1 7.8 0.1 2.2 2 0 0 2 2 2 0 Myc target protein 1 YoaP PF14268.1 EWM22036.1 - 0.096 11.9 0.0 0.23 10.7 0.0 1.6 1 0 0 1 1 1 0 YoaP-like SQS_PSY PF00494.14 EWM22037.1 - 4.3e-67 226.2 0.8 6.1e-67 225.7 0.6 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase RNA_pol_Rpb2_6 PF00562.23 EWM22038.1 - 1.4e-113 379.5 0.0 2e-113 379.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EWM22038.1 - 2.2e-26 92.0 0.0 3.5e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 EWM22038.1 - 1.5e-22 79.1 0.0 2.9e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.9 EWM22038.1 - 5.9e-19 68.2 0.0 9.2e-19 67.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EWM22038.1 - 8.6e-18 64.3 0.1 3.2e-17 62.5 0.1 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.7 EWM22038.1 - 2.1e-09 37.2 0.0 5e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_5 PF04567.12 EWM22038.1 - 4.7e-07 29.6 0.3 8.9e-07 28.7 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Peptidase_S24 PF00717.18 EWM22040.1 - 0.00065 19.3 1.2 0.0095 15.5 0.5 2.5 2 1 0 2 2 2 1 Peptidase S24-like Methyltransf_26 PF13659.1 EWM22042.1 - 7.6e-11 42.0 0.1 1.1e-10 41.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EWM22042.1 - 6.2e-10 38.7 0.1 1.3e-09 37.7 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EWM22042.1 - 1.4e-09 38.5 0.0 2.2e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM22042.1 - 1.1e-08 34.8 0.0 1.7e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM22042.1 - 1.5e-06 28.4 0.1 3.1e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EWM22042.1 - 6.6e-06 25.6 0.0 9.6e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.13 EWM22042.1 - 8.9e-06 25.3 0.0 1.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.8 EWM22042.1 - 1.4e-05 24.3 0.3 2.1e-05 23.8 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) N6_Mtase PF02384.11 EWM22042.1 - 0.00017 20.7 0.0 0.00024 20.2 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_12 PF08242.7 EWM22042.1 - 0.0003 21.2 0.0 0.0011 19.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM22042.1 - 0.00087 19.7 0.0 0.0026 18.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 EWM22042.1 - 0.00099 18.6 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 EWM22042.1 - 0.054 13.1 0.0 0.084 12.5 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Spermine_synth PF01564.12 EWM22042.1 - 0.15 11.0 0.0 0.25 10.2 0.0 1.4 2 0 0 2 2 2 0 Spermine/spermidine synthase CDC27 PF09507.5 EWM22044.1 - 4.9e-14 52.4 29.6 1.5e-06 27.7 18.3 2.4 2 0 0 2 2 2 2 DNA polymerase subunit Cdc27 Methyltransf_18 PF12847.2 EWM22045.1 - 3.2e-11 43.7 0.0 4e-07 30.6 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 EWM22045.1 - 1.3e-08 34.5 0.0 0.0013 18.3 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain PrmA PF06325.8 EWM22045.1 - 4.1e-08 32.6 0.5 9.1e-08 31.5 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ank_2 PF12796.2 EWM22045.1 - 1.3e-07 31.8 0.6 2.8e-07 30.7 0.4 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EWM22045.1 - 5.7e-07 29.5 0.1 2.4e-06 27.5 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Methyltransf_11 PF08241.7 EWM22045.1 - 2.6e-06 27.8 0.0 0.067 13.6 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 EWM22045.1 - 2.2e-05 24.4 0.3 0.0011 18.9 0.1 2.8 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_24 PF13578.1 EWM22045.1 - 6.2e-05 23.7 0.0 0.41 11.5 0.0 3.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 EWM22045.1 - 0.00014 21.6 0.0 0.02 14.6 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Ank PF00023.25 EWM22045.1 - 0.00039 20.0 0.4 0.0016 18.1 0.1 2.4 2 0 0 2 2 1 1 Ankyrin repeat MTS PF05175.9 EWM22045.1 - 0.00064 19.1 0.2 0.0045 16.3 0.2 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EWM22045.1 - 0.0037 17.6 0.0 0.16 12.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_3 PF01596.12 EWM22045.1 - 0.004 16.2 0.1 1.6 7.7 0.1 2.3 2 0 0 2 2 2 2 O-methyltransferase Ank_3 PF13606.1 EWM22045.1 - 0.017 15.3 1.3 0.19 12.0 0.0 3.2 3 0 0 3 3 2 0 Ankyrin repeat Cons_hypoth95 PF03602.10 EWM22045.1 - 0.034 13.5 0.1 0.18 11.1 0.1 2.0 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Ank_4 PF13637.1 EWM22045.1 - 0.068 13.7 0.0 0.22 12.0 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) RrnaAD PF00398.15 EWM22045.1 - 0.12 11.3 0.0 2.1 7.2 0.0 2.1 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase SWIB PF02201.13 EWM22046.1 - 5e-30 103.0 0.1 7e-30 102.5 0.1 1.2 1 0 0 1 1 1 1 SWIB/MDM2 domain Methyltransf_16 PF10294.4 EWM22047.1 - 2.8e-10 39.9 0.0 4.3e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 EWM22047.1 - 1.2e-06 28.8 0.0 2.2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM22047.1 - 1.1e-05 25.9 0.0 1.6e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM22047.1 - 5.2e-05 22.8 0.0 8.1e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM22047.1 - 6.1e-05 23.0 0.0 0.0001 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM22047.1 - 0.00017 22.0 0.0 0.00035 20.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM22047.1 - 0.0025 17.5 0.0 0.0038 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EWM22047.1 - 0.0025 17.2 0.0 0.0041 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EWM22047.1 - 0.0049 17.3 0.0 0.0099 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EWM22047.1 - 0.0052 15.9 0.0 0.007 15.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.10 EWM22047.1 - 0.025 13.9 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 CxxCxxCC PF03692.10 EWM22049.1 - 2.1e-07 31.3 7.2 8.1e-06 26.2 6.0 2.2 1 1 1 2 2 2 1 Putative zinc- or iron-chelating domain Patatin PF01734.17 EWM22050.1 - 1.5e-12 47.8 0.2 4e-05 23.6 0.0 2.4 2 0 0 2 2 2 2 Patatin-like phospholipase DER1 PF04511.10 EWM22051.1 - 1.3e-25 90.0 0.1 1.7e-25 89.6 0.1 1.1 1 0 0 1 1 1 1 Der1-like family MIP PF00230.15 EWM22052.1 - 7.3e-47 159.7 13.4 8.8e-47 159.4 9.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein H2TH PF06831.9 EWM22053.1 - 1.1e-20 73.1 0.0 1.6e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.19 EWM22053.1 - 1.9e-06 28.2 0.0 3.8e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain FbpA PF05833.6 EWM22053.1 - 0.24 9.9 0.0 0.33 9.4 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) BPL_LplA_LipB PF03099.14 EWM22054.1 - 2.2e-09 37.3 0.0 3.5e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family ArfGap PF01412.13 EWM22055.1 - 1.5e-35 121.4 0.0 2.4e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ank_2 PF12796.2 EWM22055.1 - 1.9e-05 24.9 0.0 4.2e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EWM22055.1 - 0.00045 20.3 1.0 0.0028 17.8 0.2 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EWM22055.1 - 0.0015 18.9 0.2 0.012 16.1 0.1 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM22055.1 - 0.018 15.2 0.1 11 6.5 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat PH PF00169.24 EWM22055.1 - 0.11 12.6 0.3 0.22 11.7 0.2 1.5 1 0 0 1 1 1 0 PH domain HD PF01966.17 EWM22056.1 - 5.4e-05 23.2 0.0 0.00021 21.2 0.0 2.0 1 1 0 1 1 1 1 HD domain RIO1 PF01163.17 EWM22057.1 - 3.3e-47 160.2 0.3 5.3e-47 159.6 0.2 1.3 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 EWM22057.1 - 4.3e-34 116.4 0.3 7.7e-34 115.6 0.2 1.4 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 EWM22057.1 - 2.1e-10 40.7 1.0 0.00069 19.4 0.1 3.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EWM22057.1 - 1.2e-06 27.7 0.1 2.9e-05 23.2 0.1 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EWM22057.1 - 0.013 14.6 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain Kinase-like PF14531.1 EWM22057.1 - 0.051 12.5 0.0 0.096 11.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.20 EWM22058.1 - 2e-33 115.6 0.0 7.3e-30 103.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EWM22058.1 - 9.7e-08 31.3 0.0 1.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 EWM22058.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Nop14 PF04147.7 EWM22059.1 - 1.6e-153 512.7 0.0 2.2e-153 512.2 0.0 1.0 1 0 0 1 1 1 1 Nop14-like family GATase_5 PF13507.1 EWM22060.1 - 2.7e-83 278.8 0.0 3.8e-83 278.3 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EWM22060.1 - 7.1e-31 107.2 0.6 2.1e-16 60.3 0.0 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain DUF1604 PF07713.8 EWM22060.1 - 0.093 12.5 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1604) DnaJ PF00226.26 EWM22061.1 - 4.3e-16 58.4 0.0 8.8e-16 57.4 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain MRP-S26 PF14943.1 EWM22061.1 - 0.1 12.1 10.1 0.2 11.1 7.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF2852 PF11014.3 EWM22061.1 - 4.5 7.2 8.4 5.5 6.9 3.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) PseudoU_synth_2 PF00849.17 EWM22063.1 - 1.9e-14 53.8 0.0 1.5e-13 50.8 0.0 2.1 1 1 0 1 1 1 1 RNA pseudouridylate synthase PHD PF00628.24 EWM22064.1 - 1.2e-08 34.4 10.5 2.8e-08 33.2 7.3 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EWM22064.1 - 2.8e-07 29.7 1.8 2.8e-07 29.7 1.2 2.0 2 0 0 2 2 2 1 PHD-finger Myb_DNA-binding PF00249.26 EWM22064.1 - 1.9e-06 27.8 0.0 4.3e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-HC5HC2H PF13771.1 EWM22064.1 - 0.01 15.9 2.5 0.01 15.9 1.8 1.9 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-PHD-like PF15446.1 EWM22064.1 - 0.42 9.8 6.8 0.079 12.2 1.5 2.0 1 1 1 2 2 2 0 PHD/FYVE-zinc-finger like domain C1_3 PF07649.7 EWM22064.1 - 1.8 8.6 13.4 0.55 10.3 5.8 2.3 2 0 0 2 2 2 0 C1-like domain Ribosomal_S30AE PF02482.14 EWM22065.1 - 4.3e-21 75.1 0.8 7.4e-21 74.4 0.5 1.3 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein DEAD PF00270.24 EWM22067.1 - 1.3e-40 138.6 0.0 6.5e-40 136.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EWM22067.1 - 6.8e-29 99.5 0.1 1.5e-28 98.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EWM22067.1 - 0.0062 15.6 0.0 0.0062 15.6 0.0 2.3 3 0 0 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit UCH PF00443.24 EWM22068.1 - 9.7e-52 175.7 0.0 1.4e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EWM22068.1 - 1.2e-16 61.0 0.0 8.4e-13 48.4 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase FYVE PF01363.16 EWM22069.1 - 3.2e-15 55.7 11.6 1.4e-14 53.7 8.0 2.2 1 1 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 EWM22069.1 - 0.042 13.7 9.1 0.15 11.9 6.3 2.0 1 1 0 1 1 1 0 FYVE-type zinc finger zf-DHHC PF01529.15 EWM22069.1 - 9.1 5.6 7.4 0.42 10.0 0.4 2.0 2 0 0 2 2 2 0 DHHC palmitoyltransferase Pyr_redox_dim PF02852.17 EWM22070.1 - 2.6e-13 49.9 0.0 1.6e-12 47.4 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EWM22070.1 - 2.1e-10 40.8 0.0 4.1e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EWM22070.1 - 7.8e-08 32.4 3.3 3.2e-07 30.4 2.3 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EWM22070.1 - 0.067 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GST_C_4 PF14834.1 EWM22071.1 - 0.0078 16.1 0.1 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ion_trans_2 PF07885.11 EWM22073.1 - 9.1e-13 47.7 5.7 2.7e-12 46.2 4.0 1.8 1 0 0 1 1 1 1 Ion channel BK_channel_a PF03493.13 EWM22073.1 - 1.6e-06 27.9 0.0 4.2e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Lig_chan PF00060.21 EWM22073.1 - 0.00042 20.0 1.6 0.0011 18.6 1.1 1.7 1 0 0 1 1 1 1 Ligand-gated ion channel Ion_trans PF00520.26 EWM22073.1 - 0.002 17.4 1.7 0.002 17.4 1.1 2.8 3 0 0 3 3 3 2 Ion transport protein CLP_protease PF00574.18 EWM22074.1 - 1.6e-77 259.3 0.0 2e-77 259.0 0.0 1.1 1 0 0 1 1 1 1 Clp protease ARGLU PF15346.1 EWM22075.1 - 2.1e-14 53.5 41.0 2.1e-14 53.5 28.4 2.1 2 0 0 2 2 2 1 Arginine and glutamate-rich 1 DUF763 PF05559.6 EWM22075.1 - 0.14 11.0 8.8 0.21 10.4 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF763) LMBR1 PF04791.11 EWM22075.1 - 0.7 8.4 4.0 0.89 8.0 2.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein RAP1 PF07218.6 EWM22075.1 - 1.4 6.9 6.8 1.7 6.6 4.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) LAMTOR PF15454.1 EWM22075.1 - 2.3 8.5 7.6 0.86 9.9 0.1 2.7 2 0 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Peptidase_C1 PF00112.18 EWM22076.1 - 1.3e-51 175.6 0.0 1.7e-51 175.1 0.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 EWM22076.1 - 1.7e-05 23.5 0.1 7.3e-05 21.4 0.1 1.8 2 0 0 2 2 2 1 Peptidase C1-like family Inhibitor_I29 PF08246.7 EWM22076.1 - 0.06 13.6 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) bZIP_1 PF00170.16 EWM22077.1 - 2.8e-08 33.5 19.2 4.4e-08 32.9 9.8 2.2 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EWM22077.1 - 1.7e-07 30.9 26.0 3.9e-07 29.7 11.0 2.4 2 0 0 2 2 2 2 Basic region leucine zipper DUF2167 PF09935.4 EWM22077.1 - 0.12 11.1 1.1 0.2 10.4 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2167) Strumpellin PF10266.4 EWM22077.1 - 0.45 7.8 3.4 0.59 7.4 2.4 1.0 1 0 0 1 1 1 0 Hereditary spastic paraplegia protein strumpellin Upf2 PF04050.9 EWM22077.1 - 0.88 9.3 25.7 0.11 12.2 12.0 2.1 2 0 0 2 2 2 0 Up-frameshift suppressor 2 bZIP_Maf PF03131.12 EWM22077.1 - 3.6 7.9 25.2 0.11 12.7 10.4 2.5 1 1 1 2 2 2 0 bZIP Maf transcription factor FUSC PF04632.7 EWM22077.1 - 5.2 5.3 9.1 5.7 5.2 6.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Prothymosin PF03247.9 EWM22077.1 - 7.4 6.7 31.2 7.7 6.7 4.8 2.3 2 0 0 2 2 2 0 Prothymosin/parathymosin family RRN3 PF05327.6 EWM22077.1 - 9.6 4.1 9.9 11 3.9 6.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Lipase_3 PF01764.20 EWM22078.1 - 2e-31 108.5 0.0 2.9e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 EWM22078.1 - 6.5e-05 22.4 0.1 0.00041 19.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.2 EWM22078.1 - 6.8e-05 22.8 0.2 0.00011 22.1 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EWM22078.1 - 0.0025 18.0 0.0 0.0044 17.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.2 EWM22078.1 - 0.043 13.5 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.15 EWM22078.1 - 0.1 12.0 0.2 0.24 10.7 0.0 1.6 2 0 0 2 2 2 0 Putative esterase PGAP1 PF07819.8 EWM22078.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein CLU_N PF15044.1 EWM22079.1 - 1.1e-06 28.6 0.0 1.6e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term zf-Apc11 PF12861.2 EWM22080.1 - 2.8e-36 123.2 15.0 3e-36 123.1 10.4 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EWM22080.1 - 2.7e-31 107.5 17.0 3.1e-31 107.2 11.8 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EWM22080.1 - 1.1e-07 31.5 18.6 3.3e-07 30.0 12.9 1.9 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EWM22080.1 - 0.0014 18.6 13.6 0.03 14.3 9.4 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EWM22080.1 - 0.0029 17.2 15.9 0.024 14.3 11.0 2.1 1 1 0 1 1 1 1 zinc-RING finger domain Eaf7 PF07904.8 EWM22080.1 - 0.0076 16.2 0.0 0.01 15.7 0.0 1.1 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 FANCL_C PF11793.3 EWM22080.1 - 0.0087 16.0 15.9 0.032 14.1 11.0 2.0 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4 PF00097.20 EWM22080.1 - 0.017 14.8 19.9 0.16 11.6 13.8 2.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EWM22080.1 - 0.024 14.4 4.0 0.024 14.4 2.8 2.3 2 1 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EWM22080.1 - 0.026 14.1 3.0 0.026 14.1 2.1 2.4 1 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EWM22080.1 - 0.032 13.9 5.5 0.062 13.0 3.8 1.6 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.1 EWM22080.1 - 0.039 13.6 16.8 0.32 10.6 11.7 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) GAGA PF09237.6 EWM22080.1 - 0.19 11.3 0.3 0.19 11.3 0.2 2.4 2 1 1 3 3 3 0 GAGA factor zf-Nse PF11789.3 EWM22080.1 - 0.29 10.6 7.9 0.52 9.8 5.5 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.2 EWM22080.1 - 3.2 7.8 16.3 0.19 11.7 5.9 2.3 2 1 0 2 2 2 0 RING-variant domain zf-RING-like PF08746.6 EWM22080.1 - 6.5 6.8 17.4 14 5.7 11.4 2.2 1 1 1 2 2 2 0 RING-like domain GrpE PF01025.14 EWM22081.1 - 6.4e-44 149.4 1.8 7.8e-44 149.1 1.3 1.0 1 0 0 1 1 1 1 GrpE AnfO_nitrog PF09582.5 EWM22081.1 - 0.007 15.5 0.1 0.0094 15.0 0.1 1.2 1 0 0 1 1 1 1 Iron only nitrogenase protein AnfO (AnfO_nitrog) GAF PF01590.21 EWM22082.1 - 0.0088 16.1 0.2 0.013 15.5 0.1 1.4 1 1 0 1 1 1 1 GAF domain IncA PF04156.9 EWM22083.1 - 0.0029 17.2 0.4 0.0029 17.2 0.3 1.5 2 0 0 2 2 2 1 IncA protein Gal_Lectin PF02140.13 EWM22083.1 - 0.18 12.1 0.1 0.18 12.1 0.1 2.6 3 1 0 3 3 3 0 Galactose binding lectin domain rRNA_processing PF08524.6 EWM22084.1 - 5.7e-10 39.1 13.6 2.8e-07 30.4 4.2 2.2 2 0 0 2 2 2 2 rRNA processing Myb_DNA-binding PF00249.26 EWM22086.1 - 1.8e-28 98.3 6.9 1.7e-15 56.7 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EWM22086.1 - 1.5e-22 79.4 6.3 1.7e-13 50.4 0.4 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Spt20 PF12090.3 EWM22086.1 - 0.39 10.0 6.5 0.67 9.2 4.5 1.3 1 0 0 1 1 1 0 Spt20 family FHIPEP PF00771.15 EWM22086.1 - 1.2 7.3 3.0 1.9 6.7 2.1 1.2 1 0 0 1 1 1 0 FHIPEP family YABBY PF04690.8 EWM22086.1 - 2 8.6 12.1 3.2 7.9 8.4 1.3 1 0 0 1 1 1 0 YABBY protein PRT_C PF08372.5 EWM22087.1 - 0.00025 20.5 0.2 0.00055 19.4 0.2 1.5 1 0 0 1 1 1 1 Plant phosphoribosyltransferase C-terminal Pex24p PF06398.6 EWM22087.1 - 0.11 11.2 1.3 0.2 10.3 0.9 1.4 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin SSF PF00474.12 EWM22089.1 - 5.2e-09 35.2 13.0 1.4e-08 33.7 8.2 2.2 1 1 0 1 1 1 1 Sodium:solute symporter family BSD PF03909.12 EWM22090.1 - 4.2e-06 26.4 0.4 2e-05 24.1 0.3 2.1 1 1 0 1 1 1 1 BSD domain TPR_MLP1_2 PF07926.7 EWM22090.1 - 0.01 15.5 7.5 0.01 15.5 5.2 2.4 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF641 PF04859.7 EWM22090.1 - 0.021 14.5 0.3 0.021 14.5 0.2 2.4 3 1 0 3 3 3 0 Plant protein of unknown function (DUF641) Prefoldin PF02996.12 EWM22090.1 - 0.049 13.2 12.3 0.91 9.1 0.7 3.4 4 0 0 4 4 4 0 Prefoldin subunit bZIP_1 PF00170.16 EWM22090.1 - 0.068 13.1 1.8 1.6 8.7 0.1 2.7 2 0 0 2 2 2 0 bZIP transcription factor MSG PF02349.10 EWM22090.1 - 0.22 11.5 10.2 0.16 11.9 4.0 2.6 2 1 0 2 2 2 0 Major surface glycoprotein ADIP PF11559.3 EWM22090.1 - 0.88 9.4 17.3 0.032 14.1 4.5 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding YscO PF07321.7 EWM22090.1 - 2 8.1 14.7 0.27 11.0 6.6 2.0 2 0 0 2 2 2 0 Type III secretion protein YscO DUF4201 PF13870.1 EWM22090.1 - 3.5 7.0 14.0 0.18 11.2 3.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) IncA PF04156.9 EWM22090.1 - 4.7 6.7 20.7 0.081 12.5 5.3 2.3 2 0 0 2 2 2 0 IncA protein Spc24 PF08286.6 EWM22090.1 - 4.9 6.8 15.3 1.6 8.4 0.1 3.3 2 2 1 3 3 3 0 Spc24 subunit of Ndc80 Peptidase_C26 PF07722.8 EWM22091.1 - 2.8e-25 89.0 0.0 1.5e-24 86.7 0.0 1.9 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.23 EWM22091.1 - 5e-10 39.1 0.0 7.9e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Formyl_trans_N PF00551.14 EWM22092.1 - 1.6e-36 125.5 0.0 3e-36 124.6 0.0 1.4 2 0 0 2 2 2 1 Formyl transferase Formyl_trans_C PF02911.13 EWM22092.1 - 4.6e-19 68.3 0.0 7.4e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain KH_1 PF00013.24 EWM22093.1 - 2.8e-65 215.8 8.3 1.9e-10 40.2 0.2 13.0 13 1 0 13 13 13 9 KH domain KH_3 PF13014.1 EWM22093.1 - 1.3e-35 120.4 20.4 1.9e-05 24.1 0.0 9.8 10 0 0 10 10 10 7 KH domain KH_2 PF07650.12 EWM22093.1 - 5e-13 48.4 13.9 0.25 10.9 0.0 8.0 7 0 0 7 7 7 5 KH domain SLS PF14611.1 EWM22093.1 - 2.8e-12 46.5 0.0 0.31 10.4 0.0 7.4 5 3 3 8 8 8 4 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.1 EWM22093.1 - 3.7e-05 23.2 4.1 0.026 14.1 0.0 5.2 5 0 0 5 5 5 1 KH domain GxGYxYP PF14323.1 EWM22094.1 - 2.6e-07 29.7 0.0 3.7e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 GxGYxY sequence motif in domain of unknown function FAD_oxidored PF12831.2 EWM22095.1 - 5.6e-06 25.6 0.1 6.4e-06 25.5 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EWM22095.1 - 9.9e-06 24.8 0.0 1.4e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EWM22095.1 - 1.7e-05 23.8 0.1 1.9e-05 23.7 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EWM22095.1 - 3.2e-05 23.9 0.1 4e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EWM22095.1 - 0.00082 17.9 0.4 0.0012 17.4 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 EWM22095.1 - 0.0012 18.8 0.1 0.002 18.1 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EWM22095.1 - 0.0031 16.4 0.1 0.0037 16.1 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EWM22095.1 - 0.092 13.1 0.2 0.18 12.2 0.1 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.10 EWM22096.1 - 1.9e-37 128.6 1.0 3.3e-37 127.8 0.7 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EWM22096.1 - 7.6e-26 90.5 0.4 2.3e-25 89.0 0.1 1.8 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EWM22096.1 - 6.1e-07 29.7 0.0 2.7e-06 27.6 0.0 2.0 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EWM22096.1 - 7.4e-07 29.3 0.0 1.3e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TPR_11 PF13414.1 EWM22097.1 - 2.5e-33 113.5 12.9 7.3e-15 54.3 0.1 4.0 3 1 1 4 4 4 3 TPR repeat TPR_1 PF00515.23 EWM22097.1 - 2.1e-23 80.8 10.0 0.00015 21.2 0.0 6.0 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 EWM22097.1 - 2.8e-17 61.1 19.5 0.0032 17.2 0.1 6.0 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_12 PF13424.1 EWM22097.1 - 2e-11 43.6 7.2 0.002 18.0 0.0 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 EWM22097.1 - 2.3e-11 44.0 25.0 0.00052 20.6 0.2 5.6 4 1 1 5 5 5 3 Tetratricopeptide repeat RPAP3_C PF13877.1 EWM22097.1 - 8.7e-10 38.4 0.0 1.5e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_14 PF13428.1 EWM22097.1 - 4.2e-08 33.1 19.5 0.082 13.5 0.0 6.8 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 EWM22097.1 - 8.3e-08 31.9 12.4 0.078 12.8 0.4 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 EWM22097.1 - 7.9e-07 28.8 6.7 0.27 11.5 0.0 5.8 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 EWM22097.1 - 2.1e-06 27.0 2.4 1.1 9.2 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EWM22097.1 - 4.7e-06 26.8 12.4 0.00075 19.7 0.3 4.3 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EWM22097.1 - 0.00018 21.0 4.9 2.8 7.9 0.0 5.2 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 EWM22097.1 - 0.0025 18.1 9.1 9 7.0 0.1 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.1 EWM22097.1 - 0.062 13.2 6.4 5 7.1 0.0 5.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EWM22097.1 - 0.29 11.0 2.9 0.25 11.2 0.1 2.4 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat FAD_binding_4 PF01565.18 EWM22098.1 - 6e-24 84.0 0.0 1e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.9 EWM22098.1 - 2.9e-05 23.7 0.0 4.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase SHMT PF00464.14 EWM22099.1 - 2.3e-204 678.2 0.0 2.8e-204 677.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 EWM22099.1 - 1.1e-08 34.4 0.0 2.5e-08 33.2 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EWM22099.1 - 0.0044 15.8 0.0 0.0072 15.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V PRMT5 PF05185.11 EWM22102.1 - 2.5e-169 563.9 0.0 3.3e-169 563.5 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_26 PF13659.1 EWM22102.1 - 0.00011 22.2 0.1 0.0015 18.5 0.1 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM22102.1 - 0.0012 19.4 0.0 0.0032 18.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM22102.1 - 0.0017 17.9 0.0 0.0043 16.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.11 EWM22102.1 - 0.0026 17.4 0.0 0.0039 16.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.9 EWM22102.1 - 0.0074 15.6 0.1 0.014 14.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Afi1 PF07792.7 EWM22103.1 - 0.0084 16.1 4.9 0.0084 16.1 3.4 1.9 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Menin PF05053.8 EWM22103.1 - 0.055 11.6 11.2 0.06 11.5 7.8 1.2 1 0 0 1 1 1 0 Menin Glypican PF01153.14 EWM22103.1 - 0.49 8.9 6.9 0.67 8.4 4.8 1.2 1 0 0 1 1 1 0 Glypican LCD1 PF09798.4 EWM22103.1 - 6.1 4.6 9.7 8.5 4.2 6.8 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein CP_ATPgrasp_1 PF04174.8 EWM22104.1 - 0.13 10.8 0.0 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 A circularly permuted ATPgrasp DUF3447 PF11929.3 EWM22105.1 - 0.0071 16.1 0.3 0.012 15.3 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3447) Romo1 PF10247.4 EWM22105.1 - 0.047 13.8 0.0 0.074 13.2 0.0 1.3 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 ODV-E18 PF10717.4 EWM22105.1 - 0.29 10.5 2.8 0.14 11.6 0.6 1.5 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 CLU PF13236.1 EWM22106.1 - 4.5e-07 29.5 0.0 6.4e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Clustered mitochondria BLVR PF06375.6 EWM22106.1 - 0.0023 17.7 0.6 0.0032 17.3 0.4 1.2 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) Nucleo_P87 PF07267.6 EWM22106.1 - 1.1 7.9 3.6 1.2 7.7 2.5 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SIR2 PF02146.12 EWM22107.1 - 2.4e-10 40.4 0.0 3.5e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 EWM22107.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain TPR_12 PF13424.1 EWM22108.1 - 1e-15 57.4 8.7 6.9e-06 25.9 0.1 4.0 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 EWM22108.1 - 6.8e-07 28.8 8.3 0.00011 21.7 0.3 3.2 2 1 0 3 3 3 2 TPR repeat TPR_14 PF13428.1 EWM22108.1 - 6.5e-05 23.2 7.2 0.13 13.0 0.3 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 EWM22108.1 - 0.0001 22.1 5.7 0.66 9.9 0.6 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat eIF3_p135 PF12807.2 EWM22108.1 - 0.0008 19.3 0.0 0.0032 17.4 0.0 1.9 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_16 PF13432.1 EWM22108.1 - 0.01 16.4 6.9 0.62 10.8 0.1 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 EWM22108.1 - 0.016 15.0 3.8 0.057 13.2 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EWM22108.1 - 0.019 14.8 11.3 0.56 10.2 0.3 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 EWM22108.1 - 0.056 13.5 6.6 1.6 8.9 1.5 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EWM22108.1 - 0.062 13.6 4.1 0.34 11.2 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EWM22108.1 - 0.3 10.7 12.2 0.095 12.3 0.3 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 EWM22108.1 - 0.31 10.8 3.3 6.2 6.8 0.1 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat ABC2_membrane PF01061.19 EWM22109.1 - 3.3e-27 95.0 14.7 3.3e-27 95.0 10.2 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 EWM22109.1 - 2.1e-22 79.8 0.0 3.3e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 EWM22109.1 - 4.2e-10 39.1 7.8 6.6e-10 38.5 5.4 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.1 EWM22109.1 - 0.00012 22.2 0.0 0.49 10.3 0.0 2.1 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EWM22109.1 - 0.00016 20.9 0.0 0.00052 19.3 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EWM22109.1 - 0.012 15.6 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.10 EWM22109.1 - 0.018 13.7 0.0 0.025 13.2 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EWM22109.1 - 0.02 15.0 0.0 0.051 13.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EWM22109.1 - 0.025 13.9 0.0 0.052 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EWM22109.1 - 0.047 12.8 0.0 0.084 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 EWM22109.1 - 0.075 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 EWM22109.1 - 0.12 12.1 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EWM22109.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Ribonuc_red_lgC PF02867.10 EWM22110.1 - 0.00042 18.9 0.0 2.9 6.3 0.0 3.2 3 0 0 3 3 3 3 Ribonucleotide reductase, barrel domain HORMA PF02301.13 EWM22111.1 - 3.9e-40 137.5 0.0 1e-39 136.2 0.0 1.7 1 1 0 1 1 1 1 HORMA domain GntR PF00392.16 EWM22111.1 - 0.018 14.4 0.1 0.08 12.3 0.1 2.1 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family UFD1 PF03152.9 EWM22112.1 - 2.4e-29 101.6 0.0 2.3e-28 98.5 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 UBX PF00789.15 EWM22112.1 - 1.7e-10 40.7 0.0 2.9e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain CDC48_2 PF02933.12 EWM22112.1 - 0.003 17.1 0.0 0.025 14.2 0.0 2.3 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 Daxx PF03344.10 EWM22113.1 - 7.2 4.9 12.7 8.4 4.7 8.8 1.1 1 0 0 1 1 1 0 Daxx Family Xpo1 PF08389.7 EWM22115.1 - 2.5e-11 43.7 0.0 1.1e-10 41.6 0.0 2.2 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.14 EWM22115.1 - 0.0005 19.9 0.0 0.0075 16.1 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain TFIIA PF03153.8 EWM22116.1 - 0.012 15.5 20.2 0.016 15.1 14.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MH1 PF03165.11 EWM22116.1 - 0.4 10.7 2.3 0.52 10.3 1.2 1.7 1 1 0 1 1 1 0 MH1 domain THOC7 PF05615.8 EWM22117.1 - 5.8e-13 49.2 1.7 5.8e-13 49.2 1.2 2.0 1 1 1 2 2 2 1 Tho complex subunit 7 Mod_r PF07200.8 EWM22117.1 - 0.66 9.8 9.8 2.8 7.8 1.4 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Cse1 PF08506.5 EWM22119.1 - 5.9e-129 429.8 0.1 1.4e-128 428.6 0.0 1.6 2 0 0 2 2 2 1 Cse1 CAS_CSE1 PF03378.10 EWM22119.1 - 2.1e-99 332.7 0.0 4.1e-99 331.8 0.0 1.4 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus IBN_N PF03810.14 EWM22119.1 - 2.9e-09 36.7 0.0 1.1e-08 34.8 0.0 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EWM22119.1 - 0.00023 21.0 0.1 0.0057 16.5 0.0 3.2 3 0 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.17 EWM22119.1 - 0.009 16.0 2.7 0.13 12.4 0.0 3.6 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.1 EWM22119.1 - 0.0091 16.2 0.0 0.75 10.1 0.0 3.7 3 0 0 3 3 3 1 HEAT repeats Arm PF00514.18 EWM22119.1 - 0.06 13.1 0.6 0.49 10.2 0.3 2.6 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EWM22119.1 - 0.07 13.6 2.2 0.85 10.1 0.0 4.1 4 0 0 4 4 4 0 HEAT-like repeat DUF1221 PF06760.6 EWM22119.1 - 0.085 12.1 0.1 4.2 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1221) Arf PF00025.16 EWM22120.1 - 1e-68 230.0 0.0 1.1e-68 229.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EWM22120.1 - 3.3e-12 46.0 0.0 4e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EWM22120.1 - 2.1e-11 43.1 1.4 1.8e-05 23.5 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 EWM22120.1 - 2.9e-10 40.6 0.0 3.7e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EWM22120.1 - 3.7e-09 36.0 0.0 4.7e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EWM22120.1 - 2.4e-07 30.1 0.0 3.1e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EWM22120.1 - 5.5e-07 29.5 0.0 7.4e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EWM22120.1 - 1.9e-05 24.1 0.0 0.00019 20.9 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arch_ATPase PF01637.13 EWM22120.1 - 0.079 12.6 0.3 0.11 12.1 0.2 1.2 1 0 0 1 1 1 0 Archaeal ATPase PduV-EutP PF10662.4 EWM22120.1 - 0.12 11.8 0.1 0.28 10.6 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ComX PF05952.7 EWM22120.1 - 0.14 11.7 0.1 0.34 10.4 0.1 1.7 1 0 0 1 1 1 0 Bacillus competence pheromone ComX eIF-1a PF01176.14 EWM22121.1 - 2.6e-09 36.3 0.2 1.8e-08 33.6 0.1 2.1 1 1 0 1 1 1 1 Translation initiation factor 1A / IF-1 PRMT5 PF05185.11 EWM22122.1 - 2.8e-11 43.0 0.0 3.6e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PrmA PF06325.8 EWM22122.1 - 1.3e-08 34.3 0.0 1.8e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EWM22122.1 - 5.9e-08 33.2 0.0 1.2e-07 32.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM22122.1 - 1.2e-06 28.1 0.0 1.8e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM22122.1 - 1.3e-06 28.4 0.0 6.9e-06 26.0 0.0 2.0 1 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EWM22122.1 - 2.2e-06 27.1 0.0 4.6e-06 26.1 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_9 PF08003.6 EWM22122.1 - 4e-05 22.4 0.0 5.8e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.15 EWM22122.1 - 0.00011 21.3 0.1 0.00016 20.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 EWM22122.1 - 0.00023 21.5 0.0 0.00057 20.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM22122.1 - 0.0015 18.2 0.0 0.003 17.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM22122.1 - 0.0084 16.4 0.0 0.035 14.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain GidB PF02527.10 EWM22122.1 - 0.017 14.2 0.0 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Cons_hypoth95 PF03602.10 EWM22122.1 - 0.041 13.2 0.5 0.059 12.7 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Methyltransf_16 PF10294.4 EWM22122.1 - 0.05 13.0 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Cystatin PF00031.16 EWM22123.1 - 1.1e-08 35.1 0.0 1.6e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Cystatin domain DUF1518 PF07469.7 EWM22124.1 - 0.13 12.4 0.5 0.26 11.4 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1518) Aldedh PF00171.17 EWM22125.1 - 1.8e-135 451.8 0.0 2.3e-135 451.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fer4_13 PF13370.1 EWM22126.1 - 1.3e-08 35.1 0.3 3e-08 33.9 0.2 1.6 1 1 0 1 1 1 1 4Fe-4S single cluster domain Lactamase_B PF00753.22 EWM22126.1 - 1.4e-08 34.5 2.0 3.2e-08 33.4 1.4 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Fer4_15 PF13459.1 EWM22126.1 - 4.2e-07 30.4 0.4 9.4e-07 29.3 0.3 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Metallophos PF00149.23 EWM22127.1 - 7.8e-06 25.4 0.0 0.0019 17.6 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EWM22127.1 - 5.1e-05 23.1 0.0 0.076 12.8 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain EMP70 PF02990.11 EWM22128.1 - 2.9e-149 497.8 19.8 7.3e-149 496.5 13.7 1.6 1 1 0 1 1 1 1 Endomembrane protein 70 CorA PF01544.13 EWM22128.1 - 0.084 11.8 0.2 0.084 11.8 0.1 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF1129 PF06570.6 EWM22128.1 - 8.3 5.6 16.0 0.048 12.9 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Pkinase PF00069.20 EWM22129.1 - 5e-16 58.6 0.0 7.6e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PIP49_C PF12260.3 EWM22129.1 - 0.028 13.8 0.0 2 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 zf-Tim10_DDP PF02953.10 EWM22130.1 - 2.1e-18 65.3 3.3 2.1e-18 65.3 2.3 1.6 1 1 1 2 2 2 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EWM22130.1 - 0.29 10.5 4.7 0.48 9.8 3.3 1.3 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Glycos_transf_2 PF00535.21 EWM22131.1 - 1.8e-25 89.5 0.0 2.3e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EWM22131.1 - 1.4e-13 51.1 0.1 2e-13 50.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Spc97_Spc98 PF04130.8 EWM22132.1 - 1.7e-87 294.0 0.0 2e-87 293.7 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family ETC_C1_NDUFA4 PF04800.7 EWM22133.1 - 8e-25 86.6 2.4 1.3e-24 86.0 1.6 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region Oest_recep PF02159.10 EWM22133.1 - 0.011 15.8 2.0 0.072 13.2 0.7 2.1 2 0 0 2 2 2 0 Oestrogen receptor Auts2 PF15336.1 EWM22133.1 - 0.012 15.6 0.6 0.021 14.8 0.4 1.4 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein DEAD PF00270.24 EWM22134.1 - 4.5e-44 149.9 0.0 6.8e-44 149.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EWM22134.1 - 8.6e-20 70.3 0.0 1.8e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EWM22134.1 - 4.1e-19 67.8 0.1 8.2e-19 66.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EWM22134.1 - 0.001 18.9 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EWM22134.1 - 0.06 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain RNA_POL_M_15KD PF02150.11 EWM22135.1 - 8.8e-06 25.3 5.4 3.4e-05 23.4 1.7 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.13 EWM22135.1 - 4.2e-05 23.0 0.8 4.2e-05 23.0 0.5 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Ogr_Delta PF04606.7 EWM22135.1 - 0.0043 16.6 1.8 0.0043 16.6 1.3 3.1 3 0 0 3 3 3 1 Ogr/Delta-like zinc finger zf-ribbon_3 PF13248.1 EWM22135.1 - 0.0062 15.7 2.5 0.15 11.2 0.1 2.9 3 0 0 3 3 3 1 zinc-ribbon domain Snf7 PF03357.16 EWM22136.1 - 4.7e-27 94.4 15.1 4.7e-27 94.4 10.4 1.5 1 1 0 1 1 1 1 Snf7 APG6 PF04111.7 EWM22136.1 - 0.0056 15.7 0.3 0.0056 15.7 0.2 1.8 1 1 1 2 2 2 1 Autophagy protein Apg6 Sporozoite_P67 PF05642.6 EWM22136.1 - 0.014 13.3 1.7 0.019 12.8 1.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen THF_DHG_CYH_C PF02882.14 EWM22137.1 - 1.7e-14 53.2 0.1 8.1e-13 47.7 0.2 3.0 2 1 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EWM22137.1 - 6.1e-14 52.0 0.0 1e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 2-Hacid_dh_C PF02826.14 EWM22137.1 - 0.005 16.0 0.0 0.02 14.0 0.0 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain LRR_6 PF13516.1 EWM22138.1 - 2.8e-33 110.1 5.3 0.0021 17.9 0.0 10.6 10 0 0 10 10 10 9 Leucine Rich repeat LRR_4 PF12799.2 EWM22138.1 - 3.1e-18 64.9 0.1 0.011 15.3 0.1 7.3 6 1 0 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EWM22138.1 - 2.5e-11 41.9 3.6 3.9 7.8 0.0 9.4 9 1 0 9 9 9 2 Leucine Rich Repeat LRR_7 PF13504.1 EWM22138.1 - 2.5e-06 26.7 18.3 14 6.4 0.0 9.7 11 0 0 11 11 11 2 Leucine rich repeat LRR_8 PF13855.1 EWM22138.1 - 4.4e-06 26.3 10.1 2.5 7.9 0.1 8.3 7 2 0 7 7 7 1 Leucine rich repeat PT PF04886.7 EWM22139.1 - 3.8e-13 48.4 84.9 4.8e-06 25.7 12.0 5.5 3 1 1 4 4 4 4 PT repeat Cyt-b5 PF00173.23 EWM22140.1 - 0.058 13.2 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain DUF3747 PF12565.3 EWM22141.1 - 0.083 11.9 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3747) Na_Ca_ex PF01699.19 EWM22142.1 - 5.6e-41 139.4 26.0 1.3e-21 76.6 6.7 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Exo_endo_phos PF03372.18 EWM22143.1 - 3.8e-09 36.8 0.0 3.4e-07 30.4 0.0 2.3 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family DXP_synthase_N PF13292.1 EWM22144.1 - 6.4e-104 346.6 0.0 1.4e-103 345.5 0.0 1.6 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.19 EWM22144.1 - 5.1e-41 140.1 0.0 9.3e-41 139.2 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EWM22144.1 - 6.3e-24 84.2 0.0 1.3e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transketolase_N PF00456.16 EWM22144.1 - 1.4e-05 24.0 0.0 0.23 10.2 0.0 3.0 3 0 0 3 3 3 2 Transketolase, thiamine diphosphate binding domain E1_dh PF00676.15 EWM22144.1 - 0.022 13.4 0.1 0.037 12.7 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component ER_lumen_recept PF00810.13 EWM22145.1 - 1.5e-51 174.7 7.1 1.5e-51 174.7 4.9 1.5 2 0 0 2 2 2 1 ER lumen protein retaining receptor IPK PF03770.11 EWM22146.1 - 9.5e-31 106.9 0.0 1.2e-17 64.2 0.0 2.1 2 0 0 2 2 2 2 Inositol polyphosphate kinase WD40 PF00400.27 EWM22147.1 - 7.1e-19 66.9 8.7 9.6e-06 25.2 0.1 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat RWP-RK PF02042.10 EWM22148.1 - 1e-21 76.4 0.5 2.3e-21 75.3 0.3 1.6 1 0 0 1 1 1 1 RWP-RK domain PspA_IM30 PF04012.7 EWM22149.1 - 6.5e-54 182.6 23.0 8.7e-54 182.2 16.0 1.2 1 0 0 1 1 1 1 PspA/IM30 family TBPIP PF07106.8 EWM22149.1 - 0.00091 18.8 13.3 0.052 13.0 1.7 2.5 2 0 0 2 2 2 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) LAGLIDADG_WhiA PF14527.1 EWM22149.1 - 0.021 14.6 0.6 0.056 13.3 0.4 1.8 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain Syntaxin_2 PF14523.1 EWM22149.1 - 0.082 12.9 5.4 0.16 11.9 0.1 2.6 2 0 0 2 2 2 0 Syntaxin-like protein DUF2937 PF11157.3 EWM22149.1 - 0.17 11.2 8.6 0.044 13.1 2.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2937) Spc7 PF08317.6 EWM22149.1 - 0.17 10.4 16.1 0.39 9.3 11.2 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Nup54 PF13874.1 EWM22149.1 - 0.17 11.5 15.8 0.16 11.5 3.6 2.6 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 RTX_C PF08339.5 EWM22149.1 - 0.18 11.5 5.6 0.34 10.6 3.1 2.0 1 1 1 2 2 2 0 RTX C-terminal domain V_ATPase_I PF01496.14 EWM22149.1 - 0.46 8.2 8.1 0.58 7.9 5.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2120 PF09893.4 EWM22149.1 - 0.5 10.3 4.3 0.29 11.0 0.6 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) HlyD_2 PF12700.2 EWM22149.1 - 1.3 8.1 13.7 2 7.4 9.5 1.4 1 1 0 1 1 1 0 HlyD family secretion protein DUF484 PF04340.7 EWM22149.1 - 2.6 7.4 11.4 0.26 10.7 3.6 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF484 SlyX PF04102.7 EWM22149.1 - 3.4 8.0 14.3 0.51 10.7 0.6 3.4 2 1 1 3 3 3 0 SlyX NPV_P10 PF05531.7 EWM22149.1 - 4.5 7.5 7.1 8.1 6.7 0.7 3.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein PhoU PF01895.14 EWM22149.1 - 4.6 7.7 7.5 2.3 8.7 1.0 3.0 1 1 2 3 3 3 0 PhoU domain Prefoldin_2 PF01920.15 EWM22149.1 - 7.4 6.3 20.5 0.74 9.6 1.1 3.7 2 1 0 3 3 2 0 Prefoldin subunit Aminotran_5 PF00266.14 EWM22150.1 - 1.3e-28 99.7 0.0 7.2e-14 51.3 0.0 3.1 3 0 0 3 3 3 3 Aminotransferase class-V Globin PF00042.17 EWM22150.1 - 6.7e-10 39.2 0.0 1.2e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 Globin Aminotran_1_2 PF00155.16 EWM22150.1 - 0.0067 15.4 0.0 0.016 14.2 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II ApbA PF02558.11 EWM22153.1 - 1.5e-24 86.1 0.0 6.6e-13 48.3 0.0 2.2 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EWM22153.1 - 6.4e-18 64.9 0.0 2.2e-17 63.1 0.0 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal NAD_binding_10 PF13460.1 EWM22153.1 - 0.013 15.5 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding Cyclin_N PF00134.18 EWM22155.1 - 0.2 11.2 0.0 0.2 11.2 0.0 2.8 3 0 0 3 3 3 0 Cyclin, N-terminal domain ATP_bind_1 PF03029.12 EWM22156.1 - 2.9e-74 249.5 0.0 8.7e-74 248.0 0.0 1.6 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_19 PF13245.1 EWM22156.1 - 5.7e-06 25.9 0.2 2.8e-05 23.7 0.1 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 EWM22156.1 - 0.00018 22.3 0.0 0.00057 20.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 EWM22156.1 - 0.0002 21.0 0.0 0.00045 19.9 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 EWM22156.1 - 0.00023 20.0 0.0 0.00038 19.3 0.0 1.3 1 0 0 1 1 1 1 ArgK protein AAA_31 PF13614.1 EWM22156.1 - 0.00064 19.6 0.0 0.017 15.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EWM22156.1 - 0.00096 18.6 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain CbiA PF01656.18 EWM22156.1 - 0.0013 18.1 0.0 0.0039 16.6 0.0 1.8 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.1 EWM22156.1 - 0.0035 17.2 0.0 0.0088 15.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EWM22156.1 - 0.0046 17.1 0.0 0.0078 16.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) GRP PF07172.6 EWM22156.1 - 0.0087 16.5 0.3 0.015 15.7 0.2 1.4 1 0 0 1 1 1 1 Glycine rich protein family AAA_30 PF13604.1 EWM22156.1 - 0.0092 15.5 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EWM22156.1 - 0.02 14.8 0.0 0.059 13.3 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase SRP54 PF00448.17 EWM22156.1 - 0.02 14.3 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EWM22156.1 - 0.039 13.3 0.0 0.39 10.1 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EWM22156.1 - 0.068 13.1 0.0 0.44 10.5 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain NTPase_1 PF03266.10 EWM22156.1 - 0.084 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.1 EWM22156.1 - 0.093 12.8 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.10 EWM22156.1 - 0.11 11.5 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase ATP_bind_1 PF03029.12 EWM22157.1 - 8.2e-47 159.7 0.0 2.6e-46 158.0 0.0 1.7 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein GRP PF07172.6 EWM22157.1 - 0.0061 17.0 0.3 0.0096 16.3 0.2 1.4 1 0 0 1 1 1 1 Glycine rich protein family Tom22 PF04281.8 EWM22158.1 - 2.8e-05 23.6 0.2 3.7e-05 23.2 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Tic20 PF09685.5 EWM22158.1 - 0.12 12.3 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Tic20-like protein HATPase_c PF02518.21 EWM22159.1 - 4.5e-18 64.9 0.0 8.7e-18 64.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BCDHK_Adom3 PF10436.4 EWM22159.1 - 1e-06 28.3 0.0 2.5e-06 27.0 0.0 1.6 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c_3 PF13589.1 EWM22159.1 - 0.00031 20.4 0.0 0.00046 19.8 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4505 PF14956.1 EWM22160.1 - 1.8e-28 99.3 0.0 2.7e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4505) PGK PF00162.14 EWM22161.1 - 8.7e-132 439.2 0.5 9.8e-132 439.1 0.4 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase IF2_N PF04760.10 EWM22161.1 - 0.031 13.9 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region DUF1635 PF07795.6 EWM22162.1 - 0.052 12.9 0.2 0.052 12.9 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1635) Spore_III_AF PF09581.5 EWM22162.1 - 0.36 10.6 3.0 0.97 9.2 2.0 1.8 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) TMF_DNA_bd PF12329.3 EWM22162.1 - 0.42 10.4 20.4 0.21 11.4 1.1 3.9 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding IFT57 PF10498.4 EWM22162.1 - 0.97 8.1 7.6 0.9 8.2 4.2 1.7 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 HAUS-augmin3 PF14932.1 EWM22162.1 - 3.9 6.6 20.3 6.3 5.9 0.1 3.3 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 3 Abhydro_lipase PF04083.11 EWM22164.1 - 2.9e-10 39.3 0.0 3.6e-09 35.8 0.0 2.6 2 1 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EWM22164.1 - 3.9e-09 36.3 0.0 5.5e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EWM22164.1 - 8.2e-06 25.8 0.5 1.6e-05 24.8 0.3 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM22164.1 - 0.00031 20.5 0.1 0.00058 19.6 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peripla_BP_6 PF13458.1 EWM22164.1 - 0.024 13.9 0.1 0.024 13.9 0.0 2.2 3 0 0 3 3 3 0 Periplasmic binding protein Papilloma_E5A PF05776.7 EWM22164.1 - 0.062 13.4 3.3 0.12 12.5 2.3 1.4 1 0 0 1 1 1 0 Papillomavirus E5A protein BP28CT PF08146.7 EWM22165.1 - 1.8e-25 89.4 0.0 4.4e-25 88.2 0.0 1.6 1 0 0 1 1 1 1 BP28CT (NUC211) domain HEAT_2 PF13646.1 EWM22165.1 - 0.053 13.8 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 HEAT repeats HEAT_EZ PF13513.1 EWM22165.1 - 0.067 13.7 1.0 0.37 11.3 0.0 2.8 3 1 1 4 4 4 0 HEAT-like repeat Acyl_transf_3 PF01757.17 EWM22166.1 - 2e-11 43.3 33.9 2e-11 43.3 23.5 2.5 2 0 0 2 2 2 1 Acyltransferase family Chloroa_b-bind PF00504.16 EWM22167.1 - 1.1e-38 132.9 0.0 1.5e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DUF2905 PF11146.3 EWM22167.1 - 0.001 18.9 0.4 11 6.0 0.0 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF2905) Abhydrolase_5 PF12695.2 EWM22168.1 - 0.044 13.5 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PPR PF01535.15 EWM22169.1 - 2e-10 39.9 0.5 0.0032 17.3 0.0 5.2 6 0 0 6 6 6 2 PPR repeat PPR_3 PF13812.1 EWM22169.1 - 6.5e-08 32.2 6.0 1 9.8 0.0 5.7 7 0 0 7 7 7 3 Pentatricopeptide repeat domain PPR_2 PF13041.1 EWM22169.1 - 4.4e-07 29.7 0.0 4.7e-05 23.2 0.0 3.3 4 0 0 4 4 4 1 PPR repeat family TPR_2 PF07719.12 EWM22169.1 - 0.13 12.2 2.1 28 4.9 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_1 PF12854.2 EWM22169.1 - 0.15 11.5 0.0 3.1 7.3 0.1 2.8 3 0 0 3 3 3 0 PPR repeat CDH PF02611.10 EWM22170.1 - 4.7e-07 29.2 0.0 2.9e-06 26.6 0.0 2.0 1 1 0 1 1 1 1 CDP-diacylglycerol pyrophosphatase ABC2_membrane PF01061.19 EWM22171.1 - 4.3e-76 254.7 55.3 3.6e-42 143.9 15.8 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EWM22171.1 - 5.1e-39 133.6 0.0 3.1e-21 76.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_25 PF13481.1 EWM22171.1 - 6.4e-11 42.0 0.2 8.5e-05 22.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 EWM22171.1 - 2.7e-08 34.1 0.0 0.054 13.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EWM22171.1 - 1.3e-07 31.8 1.3 0.00053 20.0 0.0 3.2 3 1 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 EWM22171.1 - 2.8e-07 29.9 2.2 0.016 14.7 0.5 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EWM22171.1 - 8.7e-07 28.2 0.1 0.014 14.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_33 PF13671.1 EWM22171.1 - 1.6e-06 28.0 0.2 0.0052 16.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EWM22171.1 - 3.3e-05 24.0 0.0 0.27 11.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EWM22171.1 - 3.7e-05 23.3 1.2 0.02 14.6 0.1 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_23 PF13476.1 EWM22171.1 - 4.8e-05 23.7 0.1 0.24 11.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 EWM22171.1 - 6.6e-05 22.4 0.3 0.11 11.9 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 EWM22171.1 - 0.00015 21.7 0.4 0.31 10.9 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EWM22171.1 - 0.00015 22.5 0.6 0.26 12.1 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EWM22171.1 - 0.00058 20.0 0.8 0.038 14.1 0.0 2.7 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EWM22171.1 - 0.00066 19.3 0.3 0.44 10.1 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.1 EWM22171.1 - 0.00084 19.6 0.4 0.8 10.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EWM22171.1 - 0.0012 18.1 0.0 0.1 11.8 0.0 3.0 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain Miro PF08477.8 EWM22171.1 - 0.0012 19.3 0.2 1.1 9.7 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EWM22171.1 - 0.0019 18.1 0.3 0.25 11.3 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EWM22171.1 - 0.0024 17.0 0.4 0.29 10.2 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin ABC2_membrane_3 PF12698.2 EWM22171.1 - 0.0024 16.9 20.1 0.0024 16.9 13.9 2.8 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_10 PF12846.2 EWM22171.1 - 0.0056 16.1 1.8 0.074 12.4 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain UPF0079 PF02367.12 EWM22171.1 - 0.013 15.1 2.4 4.3 6.9 0.4 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_5 PF07728.9 EWM22171.1 - 0.013 15.1 1.1 0.14 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EWM22171.1 - 0.016 15.3 0.0 1.2 9.3 0.0 2.8 2 0 0 2 2 2 0 RNA helicase Arch_ATPase PF01637.13 EWM22171.1 - 0.034 13.8 0.1 2 8.0 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA_30 PF13604.1 EWM22171.1 - 0.051 13.1 2.4 2.7 7.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EWM22171.1 - 0.064 13.0 0.8 3.5 7.4 0.1 2.3 2 0 0 2 2 2 0 Dynamin family PDR_CDR PF06422.7 EWM22171.1 - 0.075 12.7 8.7 0.6 9.8 0.0 3.0 3 0 0 3 3 2 0 CDR ABC transporter DUF1250 PF06855.7 EWM22171.1 - 0.12 11.8 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1250) NTPase_1 PF03266.10 EWM22171.1 - 0.17 11.5 0.3 23 4.6 0.0 3.0 3 0 0 3 3 3 0 NTPase PduV-EutP PF10662.4 EWM22171.1 - 0.18 11.2 1.5 1.2 8.5 0.2 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.13 EWM22171.1 - 0.2 11.0 0.3 3.8 6.9 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_24 PF13479.1 EWM22171.1 - 0.33 10.4 2.8 4.1 6.9 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 EWM22171.1 - 0.4 10.2 0.0 0.87 9.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EWM22171.1 - 0.64 8.8 0.6 1.3 7.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_15 PF13175.1 EWM22171.1 - 1.2 8.0 0.0 8.4 5.3 0.0 2.1 3 0 0 3 3 2 0 AAA ATPase domain DUF2368 PF10166.4 EWM22172.1 - 0.056 13.0 0.1 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2368) CRIC_ras_sig PF10534.4 EWM22172.1 - 0.11 12.5 0.9 0.47 10.5 0.3 2.0 1 1 1 2 2 2 0 Connector enhancer of kinase suppressor of ras Endostatin PF06482.6 EWM22173.1 - 0.15 11.4 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Carb_anhydrase PF00194.16 EWM22174.1 - 1.4e-23 83.1 0.0 2e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Tmemb_14 PF03647.8 EWM22176.1 - 1.8e-05 25.0 6.3 2.4e-05 24.6 4.4 1.2 1 0 0 1 1 1 1 Transmembrane proteins 14C SBBP PF06739.6 EWM22178.1 - 6e-09 35.5 11.6 0.019 14.7 0.0 5.4 5 0 0 5 5 5 4 Beta-propeller repeat PQQ_2 PF13360.1 EWM22178.1 - 0.02 14.3 0.7 0.059 12.8 0.0 2.1 2 1 0 2 2 2 0 PQQ-like domain DUF1491 PF07372.7 EWM22178.1 - 0.14 12.1 0.0 0.53 10.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1491) Prefoldin PF02996.12 EWM22180.1 - 1e-25 89.6 1.4 1.4e-25 89.2 1.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 EWM22180.1 - 0.012 15.3 0.4 0.071 12.8 0.1 2.0 2 0 0 2 2 2 0 Prefoldin subunit Bap31 PF05529.7 EWM22180.1 - 0.087 12.2 0.3 0.11 11.8 0.2 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like PQQ PF01011.16 EWM22181.1 - 0.00022 20.5 0.0 1.1 8.9 0.0 3.1 2 0 0 2 2 2 2 PQQ enzyme repeat SBBP PF06739.6 EWM22181.1 - 0.003 17.3 14.0 0.0057 16.4 0.2 4.2 4 0 0 4 4 4 2 Beta-propeller repeat PT PF04886.7 EWM22181.1 - 0.0059 15.9 17.7 0.0059 15.9 12.2 3.9 2 1 1 3 3 3 1 PT repeat PQQ_3 PF13570.1 EWM22181.1 - 0.027 14.7 0.1 0.027 14.7 0.1 3.6 3 0 0 3 3 3 0 PQQ-like domain Complex1_51K PF01512.12 EWM22182.1 - 1.2e-06 28.2 0.4 1.7e-06 27.8 0.3 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit PPR_2 PF13041.1 EWM22183.1 - 3.5e-66 218.9 0.9 2.8e-09 36.8 0.1 11.1 4 2 7 11 11 11 10 PPR repeat family PPR_3 PF13812.1 EWM22183.1 - 3.8e-59 192.0 13.4 1.2e-06 28.3 0.0 13.7 13 0 0 13 13 13 11 Pentatricopeptide repeat domain PPR PF01535.15 EWM22183.1 - 1.1e-56 184.9 5.9 1.9e-05 24.2 0.0 13.4 13 0 0 13 13 13 12 PPR repeat PPR_1 PF12854.2 EWM22183.1 - 1.9e-23 81.6 8.3 7.3e-05 22.1 0.0 11.2 13 1 0 13 13 13 6 PPR repeat TPR_7 PF13176.1 EWM22183.1 - 0.045 13.5 1.4 48 4.0 0.0 5.4 6 1 0 6 6 6 0 Tetratricopeptide repeat PPR_3 PF13812.1 EWM22184.1 - 2.3e-43 142.8 14.6 0.0036 17.4 0.0 14.4 14 0 0 14 14 14 9 Pentatricopeptide repeat domain PPR_2 PF13041.1 EWM22184.1 - 1.8e-40 136.6 0.0 1.2e-07 31.5 0.0 11.5 7 3 6 13 13 13 9 PPR repeat family PPR PF01535.15 EWM22184.1 - 1e-31 106.6 6.3 0.019 14.9 0.0 13.7 14 0 0 14 14 14 8 PPR repeat PPR_1 PF12854.2 EWM22184.1 - 9.2e-08 31.4 3.5 0.0084 15.5 0.0 6.5 9 0 0 9 9 9 2 PPR repeat TPR_15 PF13429.1 EWM22184.1 - 0.00038 19.6 0.1 8.7 5.3 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EWM22184.1 - 0.051 14.2 1.8 1.6 9.4 0.1 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3509 PF12021.3 EWM22185.1 - 0.024 14.3 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3509) PLAC8 PF04749.12 EWM22188.1 - 0.55 10.8 26.2 9.9 6.7 18.3 2.2 1 1 0 1 1 1 0 PLAC8 family Ribosomal_L13e PF01294.13 EWM22191.1 - 9.4e-73 243.4 5.3 1.1e-72 243.2 3.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Herpes_capsid PF06112.6 EWM22192.1 - 4.3 7.3 6.8 5.1 7.1 4.7 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Mito_carr PF00153.22 EWM22193.1 - 8.3e-17 60.6 3.4 8.9e-05 22.1 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein SAICAR_synt PF01259.13 EWM22195.1 - 1.1e-28 100.0 0.0 1.4e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase Transferase PF02458.10 EWM22196.1 - 6.7e-07 28.0 0.0 8.1e-07 27.8 0.0 1.0 1 0 0 1 1 1 1 Transferase family Exo_endo_phos PF03372.18 EWM22199.1 - 5.1e-06 26.5 0.0 9.1e-06 25.7 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos PF03372.18 EWM22200.1 - 8e-06 25.9 0.0 1.5e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MA3 PF02847.12 EWM22202.1 - 5.7e-17 61.4 0.0 6.9e-17 61.1 0.0 1.1 1 0 0 1 1 1 1 MA3 domain NAD_Gly3P_dh_C PF07479.9 EWM22203.1 - 2.1e-23 82.6 0.0 2.4e-23 82.5 0.0 1.0 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Ureide_permease PF07168.6 EWM22205.1 - 0.054 12.1 0.0 0.072 11.7 0.0 1.1 1 0 0 1 1 1 0 Ureide permease DUF2796 PF10986.3 EWM22206.1 - 0.11 12.4 10.4 0.19 11.6 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) PBP1_TM PF14812.1 EWM22206.1 - 3.5 8.0 6.7 5.5 7.3 4.6 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nha1_C PF08619.5 EWM22206.1 - 5.2 6.2 4.8 7.7 5.6 3.3 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Nucleoplasmin PF03066.10 EWM22206.1 - 5.9 6.3 6.4 12 5.3 4.0 1.7 2 0 0 2 2 2 0 Nucleoplasmin ABC_tran PF00005.22 EWM22207.1 - 1.3e-24 87.0 0.0 2.1e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EWM22207.1 - 9.1e-08 32.3 0.1 0.0032 17.4 0.2 2.2 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EWM22207.1 - 8.2e-06 25.3 0.1 3.6e-05 23.2 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EWM22207.1 - 2.4e-05 23.7 0.1 5.2e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 EWM22207.1 - 0.00012 21.4 0.1 0.0039 16.4 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EWM22207.1 - 0.00023 20.3 0.1 0.00034 19.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 EWM22207.1 - 0.00058 20.2 0.2 0.00094 19.5 0.1 1.3 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EWM22207.1 - 0.00065 19.6 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EWM22207.1 - 0.0009 19.2 0.1 0.0013 18.7 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EWM22207.1 - 0.0025 18.6 0.0 0.0036 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.18 EWM22207.1 - 0.0085 15.9 0.1 0.014 15.1 0.1 1.3 1 0 0 1 1 1 1 Dynamin family FtsK_SpoIIIE PF01580.13 EWM22207.1 - 0.009 15.5 0.6 0.047 13.1 0.2 1.9 2 0 0 2 2 2 1 FtsK/SpoIIIE family SbcCD_C PF13558.1 EWM22207.1 - 0.02 14.7 0.1 0.081 12.8 0.1 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EWM22207.1 - 0.022 14.2 0.4 0.034 13.5 0.3 1.3 1 0 0 1 1 1 0 AAA-like domain cobW PF02492.14 EWM22207.1 - 0.025 14.0 0.1 0.039 13.3 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EWM22207.1 - 0.03 14.4 0.1 0.067 13.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 EWM22207.1 - 0.037 12.9 0.3 0.072 11.9 0.2 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.1 EWM22207.1 - 0.068 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EWM22207.1 - 0.09 12.6 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EWM22207.1 - 0.09 13.2 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Arch_ATPase PF01637.13 EWM22207.1 - 0.099 12.3 0.1 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase ArgK PF03308.11 EWM22207.1 - 0.11 11.2 0.4 0.19 10.4 0.3 1.3 1 0 0 1 1 1 0 ArgK protein NACHT PF05729.7 EWM22207.1 - 0.12 12.0 0.1 0.51 9.9 0.0 2.0 2 0 0 2 2 2 0 NACHT domain ABC_ATPase PF09818.4 EWM22207.1 - 0.12 10.8 0.1 0.34 9.4 0.1 1.6 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_28 PF13521.1 EWM22207.1 - 0.15 12.0 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain PIRT PF15099.1 EWM22208.1 - 0.32 10.2 1.4 0.47 9.6 0.0 1.8 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Glyoxalase PF00903.20 EWM22209.1 - 7.1e-06 26.0 0.0 0.046 13.7 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EWM22209.1 - 2e-05 24.5 0.0 0.025 14.5 0.0 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.1 EWM22209.1 - 6.7e-05 22.8 0.1 0.00042 20.2 0.0 2.3 3 0 0 3 3 3 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase PF00903.20 EWM22210.1 - 6.1e-06 26.2 0.0 0.042 13.8 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EWM22210.1 - 1.7e-05 24.7 0.0 0.024 14.6 0.0 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.1 EWM22210.1 - 6e-05 22.9 0.1 0.00039 20.3 0.0 2.3 3 0 0 3 3 3 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Sgf11 PF08209.6 EWM22211.1 - 0.047 13.0 1.4 0.84 8.9 0.4 2.6 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) PAE PF03283.8 EWM22212.1 - 5.8e-55 186.3 0.0 7.1e-55 186.1 0.0 1.0 1 0 0 1 1 1 1 Pectinacetylesterase Abhydrolase_3 PF07859.8 EWM22212.1 - 0.15 11.5 0.5 5.3 6.5 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Macoilin PF09726.4 EWM22213.1 - 0.46 8.7 25.8 0.81 7.8 17.9 1.3 1 0 0 1 1 1 0 Transmembrane protein Macoilin PF09726.4 EWM22214.1 - 0.6 8.3 26.2 1.1 7.4 18.2 1.3 1 0 0 1 1 1 0 Transmembrane protein Nt_Gln_amidase PF09764.4 EWM22215.1 - 5.5e-44 149.6 0.0 2.3e-32 111.7 0.0 2.1 2 0 0 2 2 2 2 N-terminal glutamine amidase ZZ PF00569.12 EWM22216.1 - 0.91 9.1 7.6 1.6 8.3 5.2 1.4 1 0 0 1 1 1 0 Zinc finger, ZZ type Sox_N PF12444.3 EWM22217.1 - 0.61 11.2 2.9 4.2 8.5 0.1 2.3 2 0 0 2 2 2 0 Sox developmental protein N terminal BACK PF07707.10 EWM22218.1 - 0.03 14.1 0.0 0.24 11.2 0.0 2.1 1 1 0 1 1 1 0 BTB And C-terminal Kelch Ustilago_mating PF05722.7 EWM22220.1 - 0.0039 16.5 0.0 0.0056 16.0 0.0 1.2 1 0 0 1 1 1 1 Ustilago B locus mating-type protein PAE PF03283.8 EWM22220.1 - 0.014 14.0 0.4 0.082 11.5 0.0 1.9 2 0 0 2 2 2 0 Pectinacetylesterase DUF4428 PF14471.1 EWM22220.1 - 0.026 14.2 1.7 0.042 13.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) NT-C2 PF10358.4 EWM22222.1 - 2.6e-05 23.7 0.0 3.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins SBF PF01758.11 EWM22224.1 - 1.8e-46 157.9 15.0 4e-46 156.7 10.4 1.6 1 0 0 1 1 1 1 Sodium Bile acid symporter family BTB PF00651.26 EWM22225.1 - 0.012 15.5 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain CDC45 PF02724.9 EWM22225.1 - 0.033 12.2 6.1 0.038 12.0 4.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 EWM22225.1 - 0.16 10.4 6.5 0.18 10.2 4.5 1.1 1 0 0 1 1 1 0 Daxx Family Usp PF00582.21 EWM22225.1 - 0.27 11.4 1.6 0.48 10.6 1.1 1.4 1 0 0 1 1 1 0 Universal stress protein family Spt5_N PF11942.3 EWM22225.1 - 1.2 9.7 17.8 2.3 8.8 12.3 1.4 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal VID27 PF08553.5 EWM22225.1 - 3.4 5.7 7.9 3.9 5.5 5.5 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein U79_P34 PF03064.11 EWM22225.1 - 5.9 6.3 14.0 9.4 5.6 9.7 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Paf1 PF03985.8 EWM22225.1 - 5.9 5.5 12.4 7.3 5.2 8.6 1.1 1 0 0 1 1 1 0 Paf1 PolC_DP2 PF03833.8 EWM22225.1 - 6.5 4.2 7.2 8.1 3.9 5.0 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 YqfQ PF14181.1 EWM22225.1 - 9.9 6.1 6.6 16 5.4 4.6 1.2 1 0 0 1 1 1 0 YqfQ-like protein DTW PF03942.10 EWM22226.1 - 3.7e-06 26.2 1.3 6.6e-06 25.4 0.9 1.5 1 1 0 1 1 1 1 DTW domain DUF1469 PF07332.6 EWM22227.1 - 1.4 8.6 8.4 0.061 13.0 2.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) LMWPc PF01451.16 EWM22228.1 - 9.3e-25 87.5 0.0 1.1e-24 87.3 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Ank_2 PF12796.2 EWM22229.1 - 7.7e-43 144.7 4.7 6.6e-21 74.4 0.1 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EWM22229.1 - 7.6e-27 91.7 1.4 1.4e-07 30.9 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 EWM22229.1 - 1.2e-22 79.8 1.2 7.6e-13 48.5 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM22229.1 - 2.1e-19 67.6 0.3 0.00028 20.8 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EWM22229.1 - 6.8e-17 61.1 3.3 1.1e-07 31.7 0.1 4.3 1 1 3 4 4 4 3 Ankyrin repeats (many copies) DUF1843 PF08898.5 EWM22229.1 - 0.22 11.5 1.2 0.35 10.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Ank_5 PF13857.1 EWM22232.1 - 1.5e-21 75.9 0.4 9.6e-09 35.2 0.0 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EWM22232.1 - 4.1e-21 75.1 0.0 4.4e-09 36.5 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EWM22232.1 - 1.5e-20 71.9 3.9 1.5e-07 30.8 0.0 5.7 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.1 EWM22232.1 - 1.6e-17 61.8 0.5 4e-05 23.4 0.0 5.5 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 EWM22232.1 - 2.8e-17 62.7 0.1 6.3e-08 32.9 0.0 4.3 2 2 2 4 4 4 4 Ankyrin repeats (many copies) TB2_DP1_HVA22 PF03134.14 EWM22232.1 - 0.00062 19.4 0.2 0.002 17.7 0.1 1.8 1 1 0 1 1 1 1 TB2/DP1, HVA22 family ADK PF00406.17 EWM22233.1 - 9.5e-12 45.0 0.0 1.3e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.1 EWM22233.1 - 5.4e-09 36.9 0.1 7.7e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EWM22233.1 - 0.00061 20.1 0.1 0.0008 19.7 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EWM22233.1 - 0.099 12.5 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EWM22233.1 - 0.1 11.7 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin Phytochelatin PF05023.9 EWM22234.1 - 9.6e-69 230.5 0.0 1.8e-36 125.0 0.0 2.3 2 0 0 2 2 2 2 Phytochelatin synthase TMEM125 PF15109.1 EWM22235.1 - 0.11 12.5 0.2 0.13 12.3 0.1 1.1 1 0 0 1 1 1 0 TMEM125 protein family LrgB PF04172.11 EWM22236.1 - 4.7e-36 123.9 11.7 9.1e-36 123.0 8.1 1.5 1 0 0 1 1 1 1 LrgB-like family TLD PF07534.11 EWM22237.1 - 2.2e-23 82.8 0.0 5.4e-23 81.5 0.0 1.7 1 1 0 1 1 1 1 TLD RhoGAP PF00620.22 EWM22237.1 - 2.1e-06 27.4 0.0 3.8e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain ELMO_CED12 PF04727.8 EWM22237.1 - 0.0072 15.8 0.0 0.019 14.5 0.0 1.7 1 0 0 1 1 1 1 ELMO/CED-12 family RUN PF02759.14 EWM22238.1 - 4e-09 36.3 0.0 5.4e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 RUN domain DUF3619 PF12279.3 EWM22240.1 - 0.02 14.9 0.7 0.037 14.1 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) zf-4CXXC_R1 PF10497.4 EWM22241.1 - 0.046 13.8 2.7 0.057 13.5 1.9 1.3 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Glyoxalase PF00903.20 EWM22242.1 - 1.2e-36 125.4 0.0 2.3e-18 66.4 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EWM22242.1 - 1.1e-26 93.4 0.8 6.7e-12 45.9 0.0 2.8 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EWM22242.1 - 5.9e-14 52.0 0.0 8.4e-06 25.7 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EWM22242.1 - 0.0046 16.8 0.0 0.069 13.0 0.0 2.4 2 0 0 2 2 2 1 Glyoxalase-like domain CAT_RBD PF03123.10 EWM22242.1 - 0.0056 16.3 0.0 3.1 7.5 0.0 3.2 4 0 0 4 4 4 1 CAT RNA binding domain Toxin_67 PF15545.1 EWM22242.1 - 0.027 14.3 0.2 0.15 11.9 0.0 2.2 2 0 0 2 2 2 0 Putative toxin 67 DUF3081 PF11280.3 EWM22242.1 - 0.049 13.1 0.0 14 5.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3081) CppA_N PF14506.1 EWM22242.1 - 0.056 13.1 0.0 7.6 6.2 0.0 2.3 2 0 0 2 2 2 0 CppA N-terminal AAA_13 PF13166.1 EWM22243.1 - 0.72 8.2 5.6 0.94 7.8 3.9 1.1 1 0 0 1 1 1 0 AAA domain Ycf1 PF05758.7 EWM22243.1 - 1.6 6.3 4.3 1.9 6.1 3.0 1.0 1 0 0 1 1 1 0 Ycf1 GvpL_GvpF PF06386.6 EWM22243.1 - 2.6 7.5 7.2 3.8 7.0 5.0 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Paf1 PF03985.8 EWM22243.1 - 2.7 6.6 8.9 3 6.4 6.1 1.1 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.9 EWM22243.1 - 3.6 5.4 9.9 4.2 5.2 6.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.9 EWM22243.1 - 5.8 6.3 9.6 5.9 6.3 6.0 1.3 1 1 0 1 1 1 0 Pox virus Ag35 surface protein NAD_binding_10 PF13460.1 EWM22245.1 - 9.6e-29 100.6 0.2 5.7e-15 55.8 0.0 2.8 1 1 1 2 2 2 2 NADH(P)-binding NmrA PF05368.8 EWM22245.1 - 1.4e-10 40.8 0.1 1.2e-08 34.5 0.1 3.0 2 1 0 2 2 2 1 NmrA-like family Epimerase PF01370.16 EWM22245.1 - 8.5e-09 35.1 0.0 2.9e-05 23.6 0.0 2.3 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EWM22245.1 - 3.2e-08 32.6 0.0 0.0032 16.2 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EWM22245.1 - 1.8e-06 27.0 0.1 0.1 11.5 0.0 3.0 2 1 1 3 3 3 2 Male sterility protein adh_short PF00106.20 EWM22245.1 - 2.3e-06 27.6 0.8 4.2e-06 26.7 0.3 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EWM22245.1 - 0.0002 21.0 0.2 0.00035 20.2 0.1 1.5 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 EWM22245.1 - 0.0068 15.3 0.1 0.55 9.0 0.0 2.6 3 0 0 3 3 3 1 RmlD substrate binding domain TrkA_N PF02254.13 EWM22245.1 - 0.022 14.7 0.1 0.052 13.5 0.0 1.7 1 1 0 1 1 1 0 TrkA-N domain DapB_N PF01113.15 EWM22245.1 - 0.032 14.1 0.1 0.076 12.9 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.10 EWM22245.1 - 0.21 10.4 0.0 7.6 5.3 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Sel1 PF08238.7 EWM22248.1 - 0.0027 18.3 20.9 0.29 11.8 1.9 5.9 5 1 1 6 6 6 2 Sel1 repeat DUF4231 PF14015.1 EWM22248.1 - 0.078 12.9 0.1 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) PAP_fibrillin PF04755.7 EWM22249.1 - 1.5e-18 67.2 0.1 6.5e-17 61.9 0.1 2.1 1 1 0 1 1 1 1 PAP_fibrillin Asp PF00026.18 EWM22250.1 - 1.9e-99 332.8 0.0 2.2e-99 332.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EWM22250.1 - 1.5e-05 24.9 0.1 4.2e-05 23.5 0.1 1.7 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EWM22250.1 - 4.1e-05 23.9 0.0 0.0069 16.8 0.0 2.8 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.1 EWM22250.1 - 0.066 12.7 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal TRAM_LAG1_CLN8 PF03798.11 EWM22253.1 - 3.5e-10 39.7 11.2 2e-09 37.2 7.8 1.9 1 1 0 1 1 1 1 TLC domain ELO PF01151.13 EWM22253.1 - 0.0018 17.5 4.2 0.0018 17.5 2.9 1.5 2 0 0 2 2 2 1 GNS1/SUR4 family Trehalase PF01204.13 EWM22255.1 - 0.41 9.2 2.5 0.57 8.7 1.7 1.1 1 0 0 1 1 1 0 Trehalase Gal-3-0_sulfotr PF06990.6 EWM22256.1 - 1e-08 34.2 0.8 0.001 17.8 0.1 2.2 2 0 0 2 2 2 2 Galactose-3-O-sulfotransferase Cro PF09048.5 EWM22257.1 - 0.071 12.7 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Cro DUF4337 PF14235.1 EWM22257.1 - 8.6 6.1 9.1 6 6.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) GST_N_2 PF13409.1 EWM22258.1 - 8.1e-11 41.7 0.3 1.6e-10 40.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EWM22258.1 - 2.1e-10 40.6 0.1 1.4e-09 38.0 0.0 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EWM22258.1 - 1.7e-05 24.8 0.1 0.00045 20.3 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EWM22258.1 - 4.1e-05 23.3 0.1 7.9e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EWM22258.1 - 0.13 12.2 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin Beta-lactamase PF00144.19 EWM22259.1 - 3.4e-51 174.2 0.4 9.8e-51 172.7 0.3 1.6 1 1 0 1 1 1 1 Beta-lactamase PTPS PF01242.14 EWM22261.1 - 2.8e-20 72.2 0.0 3.5e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase ATP_transf PF09830.4 EWM22262.1 - 1e-15 57.2 0.0 1.9e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase Cupin_4 PF08007.7 EWM22263.1 - 2.6e-43 148.5 0.0 3.6e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.1 EWM22263.1 - 1.3e-07 31.3 0.0 6.4e-06 25.8 0.0 2.3 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.6 EWM22263.1 - 0.00058 19.3 0.1 0.0057 16.1 0.0 2.5 3 0 0 3 3 3 1 Cupin domain SRP54 PF00448.17 EWM22264.1 - 5.5e-07 29.2 0.3 7.2e-07 28.8 0.2 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.7 EWM22264.1 - 3.2e-05 23.1 0.2 4.1e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 EWM22264.1 - 0.0019 18.9 0.3 0.0032 18.2 0.1 1.4 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 EWM22264.1 - 0.0037 17.1 0.1 0.005 16.7 0.1 1.2 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 EWM22264.1 - 0.0043 16.6 0.1 0.0049 16.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 EWM22264.1 - 0.0081 15.8 0.6 0.014 15.1 0.4 1.4 1 1 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EWM22264.1 - 0.011 15.6 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 EWM22264.1 - 0.016 14.6 0.1 0.017 14.5 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EWM22264.1 - 0.016 15.5 0.2 0.027 14.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 EWM22264.1 - 0.026 14.1 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_30 PF13604.1 EWM22264.1 - 0.037 13.5 0.6 0.044 13.3 0.4 1.1 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.13 EWM22264.1 - 0.038 13.0 0.0 0.044 12.8 0.0 1.1 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_22 PF13401.1 EWM22264.1 - 0.05 13.7 0.2 0.077 13.1 0.1 1.3 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 EWM22264.1 - 0.054 12.7 0.1 0.066 12.4 0.1 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.24 EWM22264.1 - 0.12 12.5 0.3 0.28 11.3 0.2 1.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EWM22264.1 - 0.12 11.9 0.6 0.16 11.6 0.2 1.4 2 0 0 2 2 2 0 NACHT domain Arf PF00025.16 EWM22264.1 - 0.12 11.5 0.1 0.16 11.2 0.1 1.3 1 1 0 1 1 1 0 ADP-ribosylation factor family NB-ARC PF00931.17 EWM22264.1 - 0.14 11.0 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain DUF159 PF02586.9 EWM22265.1 - 1.1e-49 168.7 0.0 1.4e-49 168.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 Nucleoplasmin PF03066.10 EWM22266.1 - 0.19 11.2 5.7 0.29 10.6 3.9 1.2 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 EWM22266.1 - 2.7 8.3 10.3 4.7 7.5 7.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pollen_allerg_2 PF01620.11 EWM22267.1 - 0.029 14.6 0.0 0.039 14.2 0.0 1.2 1 0 0 1 1 1 0 Ribonuclease (pollen allergen) SRP_SPB PF02978.14 EWM22268.1 - 1.3e-20 73.5 3.6 1.3e-20 73.5 2.5 1.9 2 0 0 2 2 2 1 Signal peptide binding domain TraB PF01963.12 EWM22268.1 - 0.12 11.7 1.1 0.19 11.1 0.4 1.6 1 1 1 2 2 2 0 TraB family Ribosomal_L17 PF01196.14 EWM22269.1 - 3e-33 114.2 0.1 5.5e-33 113.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L17 PDZ PF00595.19 EWM22271.1 - 6.7e-05 22.9 0.0 6.7e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) RAB3GAP2_N PF14655.1 EWM22271.1 - 0.24 10.3 1.1 0.32 9.9 0.8 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus BAF1_ABF1 PF04684.8 EWM22271.1 - 1.7 7.3 4.9 2.3 6.9 3.4 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Med3 PF11593.3 EWM22271.1 - 1.9 7.6 5.5 2.6 7.2 3.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Rav1p_C PF12234.3 EWM22272.1 - 1.4e-17 63.1 0.4 1.7e-17 62.8 0.2 1.0 1 0 0 1 1 1 1 RAVE protein 1 C terminal B12D PF06522.6 EWM22277.1 - 0.031 13.9 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit adh_short PF00106.20 EWM22278.1 - 2.7e-12 46.9 0.0 3.3e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EWM22278.1 - 0.00013 21.7 0.0 0.00015 21.5 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1849 PF08904.6 EWM22279.1 - 0.01 15.2 0.3 0.017 14.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1849) Daxx PF03344.10 EWM22279.1 - 2.6 6.4 21.3 3.6 5.9 14.8 1.2 1 0 0 1 1 1 0 Daxx Family Pkinase PF00069.20 EWM22280.1 - 2.4e-68 230.1 0.0 3.3e-68 229.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM22280.1 - 2.2e-33 115.4 0.0 3e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EWM22280.1 - 1.2e-06 28.8 0.6 2.4e-06 27.9 0.4 1.4 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EWM22280.1 - 0.00011 21.2 0.0 0.00018 20.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EWM22280.1 - 0.021 13.9 0.1 0.077 12.0 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EWM22280.1 - 0.033 13.9 0.0 0.079 12.6 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family ORC6 PF05460.8 EWM22281.1 - 0.14 11.2 0.3 0.14 11.2 0.2 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF566 PF04484.7 EWM22281.1 - 5.9 6.3 5.5 6.8 6.1 3.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) SCP2 PF02036.12 EWM22282.1 - 9.7e-25 86.8 0.4 1.1e-24 86.6 0.2 1.0 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EWM22282.1 - 1.9e-06 27.8 0.1 2.2e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Helicase_C PF00271.26 EWM22283.1 - 8.8e-07 28.7 0.0 1.8e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EWM22283.1 - 0.011 15.2 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase Serglycin PF04360.7 EWM22283.1 - 0.58 9.8 2.1 24 4.6 0.1 2.5 2 0 0 2 2 2 0 Serglycin DEAD PF00270.24 EWM22284.1 - 0.014 14.8 0.0 0.038 13.4 0.0 1.6 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF3275 PF11679.3 EWM22284.1 - 0.086 12.4 1.1 0.14 11.7 0.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3275) HATPase_c_3 PF13589.1 EWM22287.1 - 2.3e-13 49.9 0.0 5.1e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EWM22287.1 - 3.1e-12 46.1 0.0 5.4e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EWM22287.1 - 0.071 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain PQQ_3 PF13570.1 EWM22288.1 - 0.2 12.0 5.2 3.7 7.9 0.1 4.2 5 0 0 5 5 5 0 PQQ-like domain PetG PF02529.10 EWM22288.1 - 2.1 7.9 5.2 0.19 11.2 0.2 1.8 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 MutL_C PF08676.6 EWM22290.1 - 4.1e-23 81.5 0.0 5.8e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 MutL C terminal dimerisation domain GDI PF00996.13 EWM22291.1 - 6.4e-79 265.3 0.1 7.1e-79 265.1 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Med31 PF05669.7 EWM22291.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 SOH1 Methyltransf_16 PF10294.4 EWM22292.1 - 1.2e-05 24.8 0.0 0.00099 18.6 0.0 2.5 3 0 0 3 3 3 2 Putative methyltransferase Methyltransf_18 PF12847.2 EWM22292.1 - 0.035 14.6 0.0 0.083 13.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Toxin_22 PF08092.6 EWM22294.1 - 0.014 15.2 0.3 0.078 12.8 0.0 2.2 2 0 0 2 2 2 0 Magi peptide toxin family DUF3311 PF11755.3 EWM22294.1 - 0.022 14.2 1.5 0.042 13.3 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3311) Syntaxin PF00804.20 EWM22295.1 - 0.087 12.9 2.6 0.15 12.2 1.7 1.5 1 1 0 1 1 1 0 Syntaxin DUF1279 PF06916.8 EWM22297.1 - 0.00016 21.9 0.0 0.00026 21.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Beach PF02138.13 EWM22298.1 - 1e-32 113.6 0.9 1.2e-32 113.4 0.6 1.0 1 0 0 1 1 1 1 Beige/BEACH domain Beach PF02138.13 EWM22300.1 - 2.7e-31 109.0 0.0 3.5e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.27 EWM22300.1 - 7.5e-07 28.7 0.0 0.0067 16.2 0.0 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat Adaptin_N PF01602.15 EWM22302.1 - 9.3e-24 83.6 0.5 1.2e-23 83.2 0.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region MMS19_N PF14500.1 EWM22302.1 - 0.058 12.6 1.6 4.3 6.5 0.2 2.0 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II Fun_ATP-synt_8 PF05933.8 EWM22303.1 - 0.034 14.1 0.1 0.073 13.1 0.1 1.5 1 0 0 1 1 1 0 Fungal ATP synthase protein 8 (A6L) PhzC-PhzF PF02567.11 EWM22304.1 - 3.3e-54 184.0 0.0 2.2e-33 115.7 0.0 2.5 3 0 0 3 3 3 2 Phenazine biosynthesis-like protein Acetyltransf_1 PF00583.19 EWM22304.1 - 3.2e-07 30.2 0.0 9.7e-07 28.7 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EWM22304.1 - 5.2e-05 23.3 0.1 0.00016 21.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EWM22304.1 - 0.0042 16.9 0.0 0.0098 15.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EWM22304.1 - 0.022 14.5 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EWM22304.1 - 0.024 14.7 0.5 0.077 13.1 0.1 2.2 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Pro_racemase PF05544.6 EWM22304.1 - 0.061 12.1 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Proline racemase Adaptin_N PF01602.15 EWM22305.1 - 2.4e-06 26.1 0.0 2.6e-06 26.0 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region PD-C2-AF1 PF09310.5 EWM22305.1 - 0.14 11.2 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 POU domain, class 2, associating factor 1 COP-gamma_platf PF08752.5 EWM22306.1 - 2.9e-12 46.6 0.0 5.3e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain DUF1990 PF09348.5 EWM22308.1 - 2.1e-22 79.4 0.5 2.1e-22 79.4 0.3 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1990) Vint PF14623.1 EWM22310.1 - 3.4e-11 42.8 0.0 4.9e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Hint-domain PT PF04886.7 EWM22310.1 - 7.7e-08 31.5 129.1 7.7e+02 -0.5 27.6 4.7 1 1 1 2 2 2 0 PT repeat Hint PF01079.15 EWM22310.1 - 0.00011 21.4 0.0 0.00017 20.8 0.0 1.2 1 0 0 1 1 1 1 Hint module Hom_end_hint PF05203.11 EWM22310.1 - 0.00041 20.1 0.0 0.00057 19.6 0.0 1.2 1 0 0 1 1 1 1 Hom_end-associated Hint RNase_PH PF01138.16 EWM22313.1 - 1.4e-38 132.2 0.0 3.4e-21 75.9 0.0 2.3 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EWM22313.1 - 5.2e-22 77.5 0.7 1.5e-16 60.0 0.1 2.5 2 0 0 2 2 2 2 3' exoribonuclease family, domain 2 PNPase PF03726.9 EWM22313.1 - 0.034 14.4 0.0 0.074 13.3 0.0 1.6 1 0 0 1 1 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain KH_1 PF00013.24 EWM22313.1 - 0.079 12.6 0.4 0.18 11.5 0.3 1.6 1 0 0 1 1 1 0 KH domain tRNA-synt_2c PF01411.14 EWM22315.1 - 2.6e-184 613.6 0.0 3.1e-184 613.3 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (A) bZIP_1 PF00170.16 EWM22316.1 - 8.4e-05 22.4 3.3 0.00016 21.5 2.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor HemX PF04375.9 EWM22316.1 - 0.025 13.1 0.1 0.04 12.5 0.0 1.2 1 0 0 1 1 1 0 HemX bZIP_2 PF07716.10 EWM22316.1 - 0.54 10.1 9.3 0.028 14.2 2.3 1.9 2 0 0 2 2 2 0 Basic region leucine zipper AhpC-TSA PF00578.16 EWM22317.1 - 1.3e-29 102.3 0.0 1.9e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EWM22317.1 - 1.7e-20 73.0 0.0 2.8e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Redoxin Trehalose_PPase PF02358.11 EWM22318.1 - 5.8e-55 185.7 0.0 7.5e-55 185.3 0.0 1.1 1 0 0 1 1 1 1 Trehalose-phosphatase HAD PF12710.2 EWM22318.1 - 0.07 13.2 0.2 1.5 8.9 0.0 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Kdo PF06293.9 EWM22319.1 - 9.5e-08 31.3 0.0 1.4e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EWM22319.1 - 1.2e-06 28.4 0.2 0.0024 17.6 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 EWM22319.1 - 1.7e-05 24.2 0.1 2.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.20 EWM22319.1 - 3.3e-05 23.1 0.0 4.1e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM22319.1 - 0.00024 20.2 0.0 0.00039 19.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH_6_hur PF04655.9 EWM22319.1 - 0.035 13.2 0.1 0.064 12.4 0.0 1.4 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase YrbL-PhoP_reg PF10707.4 EWM22319.1 - 0.037 13.3 0.0 0.25 10.6 0.0 2.0 1 1 1 2 2 2 0 PhoP regulatory network protein YrbL EcKinase PF02958.15 EWM22319.1 - 0.055 12.6 0.0 0.096 11.8 0.0 1.5 1 1 0 1 1 1 0 Ecdysteroid kinase NOB1_Zn_bind PF08772.6 EWM22320.1 - 6.7e-20 70.7 0.3 1.2e-19 69.9 0.2 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf-ribbon_3 PF13248.1 EWM22320.1 - 0.00063 18.8 0.8 0.0011 18.1 0.5 1.4 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 EWM22320.1 - 0.0022 17.7 0.4 0.0048 16.6 0.3 1.5 1 0 0 1 1 1 1 Double zinc ribbon zf-NADH-PPase PF09297.6 EWM22320.1 - 0.0024 17.3 4.6 0.25 10.9 0.2 2.5 2 0 0 2 2 2 2 NADH pyrophosphatase zinc ribbon domain Prok-RING_1 PF14446.1 EWM22320.1 - 0.0053 16.4 0.5 0.0094 15.6 0.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 Cript PF10235.4 EWM22320.1 - 0.013 15.8 0.1 0.026 14.8 0.1 1.5 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT HypA PF01155.14 EWM22320.1 - 0.058 13.0 0.1 0.089 12.4 0.1 1.3 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family A2L_zn_ribbon PF08792.5 EWM22320.1 - 0.12 11.8 0.5 0.25 10.8 0.3 1.5 1 0 0 1 1 1 0 A2L zinc ribbon domain IBR PF01485.16 EWM22320.1 - 0.21 11.5 2.9 8.9 6.2 1.1 2.3 1 1 1 2 2 2 0 IBR domain zinc_ribbon_2 PF13240.1 EWM22320.1 - 0.37 10.3 2.5 1.1 8.7 1.8 1.8 1 1 0 1 1 1 0 zinc-ribbon domain Ribosomal_L22e PF01776.12 EWM22321.1 - 3.9e-48 162.0 2.5 4.7e-48 161.8 1.7 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family EF-hand_7 PF13499.1 EWM22321.1 - 0.045 13.8 0.0 0.3 11.2 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair Pyridox_oxase_2 PF12766.2 EWM22322.1 - 2.4e-23 82.3 1.7 3.9e-23 81.6 0.3 2.0 2 1 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.15 EWM22322.1 - 0.00092 19.1 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Sugar_tr PF00083.19 EWM22323.1 - 4.8e-22 78.1 20.8 9.1e-12 44.2 5.9 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EWM22323.1 - 9.8e-11 40.9 36.9 1.8e-09 36.7 6.5 3.7 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 EWM22323.1 - 4.3 5.6 16.2 0.54 8.6 2.3 2.8 2 1 0 2 2 2 0 MFS/sugar transport protein Antistasin PF02822.9 EWM22324.1 - 0.047 13.9 0.1 0.1 12.9 0.1 1.6 1 0 0 1 1 1 0 Antistasin family zf-RING_2 PF13639.1 EWM22325.1 - 1e-08 34.8 9.2 2.2e-08 33.8 6.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EWM22325.1 - 2.2e-08 33.9 8.9 4.5e-08 32.9 6.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EWM22325.1 - 3.2e-07 30.1 8.9 6.8e-07 29.0 6.1 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EWM22325.1 - 4.1e-07 29.5 10.3 7.8e-07 28.6 7.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EWM22325.1 - 1.8e-06 27.4 9.9 4e-06 26.4 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EWM22325.1 - 9.3e-06 25.2 10.8 1.6e-05 24.4 6.9 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EWM22325.1 - 2.8e-05 23.7 7.8 5.7e-05 22.7 5.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 EWM22325.1 - 0.018 14.6 7.5 0.031 13.8 4.5 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF3551 PF12071.3 EWM22325.1 - 1.2 8.7 7.6 0.18 11.4 2.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3551) PP28 PF10252.4 EWM22326.1 - 3.5e-15 55.7 17.6 3.5e-15 55.7 12.2 2.2 2 0 0 2 2 2 1 Casein kinase substrate phosphoprotein PP28 SAP PF02037.22 EWM22326.1 - 8.3e-08 31.5 2.8 1.7e-07 30.5 2.0 1.5 1 0 0 1 1 1 1 SAP domain DUF3228 PF11539.3 EWM22327.1 - 3.3e-54 182.9 0.0 4.1e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) C1_4 PF07975.7 EWM22328.1 - 0.04 13.9 0.3 0.076 13.0 0.2 1.7 1 1 0 1 1 1 0 TFIIH C1-like domain Apt1 PF10351.4 EWM22328.1 - 0.48 9.2 24.6 0.5 9.1 17.0 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Nop14 PF04147.7 EWM22328.1 - 0.49 8.2 12.1 0.49 8.2 8.4 1.0 1 0 0 1 1 1 0 Nop14-like family DUF566 PF04484.7 EWM22328.1 - 1.3 8.4 26.0 1.4 8.4 18.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF572 PF04502.8 EWM22328.1 - 1.4 8.0 15.0 1.6 7.8 10.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF789 PF05623.7 EWM22328.1 - 2.2 7.6 11.8 3.2 7.1 8.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF789) CDC45 PF02724.9 EWM22328.1 - 2.3 6.1 22.8 2.6 5.9 15.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.4 EWM22328.1 - 2.8 6.1 27.1 2.9 6.0 18.8 1.0 1 0 0 1 1 1 0 Transmembrane protein SOBP PF15279.1 EWM22328.1 - 3.3 7.9 14.3 3.7 7.8 9.9 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein GEMIN8 PF15348.1 EWM22328.1 - 4.6 7.2 8.6 5.7 6.9 5.9 1.1 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Pox_RNA_Pol_19 PF05320.7 EWM22328.1 - 5 6.8 7.1 5.6 6.6 4.9 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Lin-8 PF03353.10 EWM22328.1 - 5.1 6.2 7.6 5.4 6.1 5.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist zf-H2C2_2 PF13465.1 EWM22328.1 - 5.4 7.4 6.1 0.63 10.4 0.3 2.0 2 0 0 2 2 2 0 Zinc-finger double domain DUF605 PF04652.11 EWM22328.1 - 8 5.7 16.6 7.6 5.8 11.5 1.0 1 0 0 1 1 1 0 Vta1 like MIP-T3 PF10243.4 EWM22328.1 - 8.1 4.7 13.7 8.4 4.7 9.5 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Hex_IIIa PF02455.11 EWM22328.1 - 8.7 4.9 8.4 9.1 4.8 5.8 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Hid1 PF12722.2 EWM22328.1 - 8.9 3.8 14.4 9.4 3.7 10.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAPS PF04499.10 EWM22328.1 - 10 4.6 9.8 11 4.5 6.8 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein eIF-3_zeta PF05091.7 EWM22330.1 - 2.1e-125 419.3 0.0 4e-77 259.9 0.0 2.0 2 0 0 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Daxx PF03344.10 EWM22330.1 - 2.8 6.3 9.5 4.3 5.6 6.6 1.2 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 EWM22330.1 - 9.7 4.0 7.5 16 3.4 5.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Aa_trans PF01490.13 EWM22331.1 - 9.7e-16 57.2 12.3 9.7e-16 57.2 8.5 1.5 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein Cu_amine_oxid PF01179.15 EWM22333.1 - 6e-156 519.3 0.0 7.1e-156 519.0 0.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EWM22333.1 - 3e-12 46.4 0.0 7.2e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EWM22333.1 - 1.1e-10 41.4 0.2 3.4e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Abhydrolase_6 PF12697.2 EWM22334.1 - 1.3e-13 51.3 1.3 2.1e-13 50.6 0.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM22334.1 - 2.5e-07 30.5 0.1 4e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EWM22334.1 - 0.0054 16.9 0.0 0.008 16.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.15 EWM22334.1 - 0.078 12.5 0.0 0.17 11.3 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold PGAP1 PF07819.8 EWM22334.1 - 0.12 11.8 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_M76 PF09768.4 EWM22335.1 - 3.7e-18 65.5 0.3 3.7e-18 65.5 0.2 1.6 2 0 0 2 2 2 1 Peptidase M76 family Peptidase_MA_2 PF13485.1 EWM22335.1 - 0.039 13.9 0.1 0.064 13.3 0.1 1.6 1 1 0 1 1 1 0 Peptidase MA superfamily Peptidase_M91 PF14891.1 EWM22335.1 - 0.32 11.0 1.1 0.77 9.7 0.7 1.8 1 1 0 1 1 1 0 Effector protein GST_C PF00043.20 EWM22337.1 - 3e-12 46.3 0.0 5.5e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EWM22337.1 - 6.8e-10 38.9 0.2 2.1e-09 37.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EWM22337.1 - 5.7e-07 29.6 0.0 1.4e-06 28.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EWM22337.1 - 1.4e-06 28.7 0.0 2.3e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EWM22337.1 - 4.7e-06 26.3 0.1 1.2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EWM22337.1 - 0.014 15.3 0.0 0.04 13.9 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Jiraiya PF15038.1 EWM22337.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Jiraiya Peptidase_M16 PF00675.15 EWM22338.1 - 1.5e-32 112.3 0.0 4e-32 111.0 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EWM22338.1 - 3.3e-28 98.6 0.0 2.9e-16 59.6 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain ACT_7 PF13840.1 EWM22339.1 - 4.8e-07 29.2 0.0 7.9e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 ACT domain ACT PF01842.20 EWM22339.1 - 0.025 14.0 0.0 0.059 12.8 0.0 1.6 1 0 0 1 1 1 0 ACT domain Tubulin PF00091.20 EWM22340.1 - 2.3e-46 158.3 0.0 3.6e-46 157.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.1 EWM22340.1 - 0.035 13.0 0.1 0.057 12.3 0.1 1.2 1 0 0 1 1 1 0 Tubulin like Vps52 PF04129.7 EWM22341.1 - 2e-129 432.4 0.3 8.1e-128 427.1 0.1 2.6 2 1 0 2 2 2 1 Vps52 / Sac2 family Sec3_C PF09763.4 EWM22341.1 - 3.5e-13 48.6 6.5 1.5e-11 43.2 1.3 2.7 2 1 0 2 2 2 2 Exocyst complex component Sec3 COG2 PF06148.6 EWM22341.1 - 0.05 13.4 0.9 0.19 11.5 0.6 2.0 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Piwi PF02171.12 EWM22342.1 - 7e-85 284.6 0.5 1.1e-84 283.9 0.4 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 EWM22342.1 - 2.1e-23 82.1 0.0 4.2e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 EWM22342.1 - 2.8e-11 42.6 0.0 5.8e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) NDUFA12 PF05071.11 EWM22343.1 - 5.5e-20 71.7 1.8 7.1e-20 71.4 0.8 1.5 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Abhydrolase_6 PF12697.2 EWM22344.1 - 1.9e-28 99.9 5.8 3.1e-28 99.2 4.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EWM22344.1 - 8.8e-13 48.3 0.0 2.6e-10 40.2 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EWM22344.1 - 4.3e-10 39.5 0.3 8.7e-10 38.5 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EWM22344.1 - 8.3e-05 21.9 0.0 0.045 13.0 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family BAAT_C PF08840.6 EWM22344.1 - 0.00095 18.9 0.0 0.0081 15.8 0.0 2.0 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal TDH PF03347.8 EWM22346.1 - 0.041 13.4 0.0 0.045 13.3 0.0 1.1 1 0 0 1 1 1 0 Vibrio thermostable direct hemolysin DUF2040 PF09745.4 EWM22348.1 - 8.1e-31 106.4 24.3 8.1e-31 106.4 16.8 2.1 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) DUF773 PF05600.7 EWM22349.1 - 4e-68 230.4 4.8 2.9e-39 135.2 0.0 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF773) Adaptin_binding PF10199.4 EWM22349.1 - 0.038 14.2 2.3 0.26 11.5 0.1 2.5 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Abhydrolase_5 PF12695.2 EWM22350.1 - 2.6e-13 49.9 0.1 6.7e-13 48.6 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EWM22350.1 - 8.7e-08 32.3 2.0 0.0083 16.0 0.3 3.5 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EWM22350.1 - 0.14 11.3 0.1 0.46 9.6 0.1 1.8 1 1 0 1 1 1 0 Prolyl oligopeptidase family IlvC PF01450.14 EWM22351.1 - 4.1e-41 140.2 0.0 1.6e-21 76.7 0.0 2.2 2 0 0 2 2 2 2 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.7 EWM22351.1 - 1.1e-32 112.6 0.0 1.9e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EWM22351.1 - 0.071 13.5 0.1 0.19 12.1 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent VHS PF00790.14 EWM22352.1 - 2.3e-26 92.0 0.3 4.4e-26 91.1 0.1 1.5 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 EWM22352.1 - 1.9e-08 34.2 0.7 2.4e-06 27.4 0.1 2.5 2 0 0 2 2 2 2 GAT domain ENTH PF01417.15 EWM22352.1 - 0.00097 18.9 0.1 0.0019 18.0 0.1 1.4 1 0 0 1 1 1 1 ENTH domain FANCI_S4 PF14678.1 EWM22352.1 - 0.1 11.7 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 FANCI solenoid 4 Ald_Xan_dh_C2 PF02738.13 EWM22353.1 - 6.8e-174 579.2 0.1 9.3e-174 578.7 0.1 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 EWM22353.1 - 1.4e-47 161.3 0.8 3.9e-47 159.8 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.17 EWM22353.1 - 1.1e-30 105.9 0.4 2.5e-30 104.8 0.3 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.12 EWM22353.1 - 2.7e-27 94.6 0.0 7.5e-27 93.2 0.0 1.7 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.15 EWM22353.1 - 6e-26 90.1 0.0 1.3e-25 89.0 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 EWM22353.1 - 2e-08 33.8 0.5 2e-08 33.8 0.4 2.5 2 1 1 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain Glycos_transf_1 PF00534.15 EWM22354.1 - 6.1e-18 64.8 0.0 3.5e-17 62.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EWM22354.1 - 2.3e-11 43.9 0.0 6.1e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EWM22354.1 - 2.3e-07 30.7 0.8 6.6e-07 29.2 0.6 1.8 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 EWM22354.1 - 0.0023 18.0 5.6 0.015 15.4 3.9 2.3 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain adh_short PF00106.20 EWM22355.1 - 1.1e-18 67.6 0.0 3.1e-18 66.2 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EWM22355.1 - 7.8e-08 32.3 0.0 1.4e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EWM22355.1 - 4.3e-07 29.7 0.0 7e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EWM22355.1 - 0.055 12.9 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fructosamin_kin PF03881.9 EWM22357.1 - 1.9e-90 302.7 0.0 2.3e-90 302.4 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EWM22357.1 - 1.2e-13 51.3 0.1 2.1e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EspF PF04806.7 EWM22357.1 - 0.11 12.7 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 EspF protein repeat ECH PF00378.15 EWM22359.1 - 2.1e-22 79.4 0.1 5.1e-22 78.1 0.1 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF393 PF04134.7 EWM22359.1 - 5.1e-20 72.6 0.0 1e-19 71.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF393 ECH_C PF13766.1 EWM22359.1 - 1.9e-12 47.3 0.0 3e-08 33.8 0.0 2.5 2 0 0 2 2 2 2 2-enoyl-CoA Hydratase C-terminal region G-patch PF01585.18 EWM22360.1 - 0.00087 19.0 7.8 0.0031 17.2 5.5 1.8 1 1 1 2 2 2 1 G-patch domain zf-C2H2_jaz PF12171.3 EWM22360.1 - 0.0015 18.5 0.3 0.0031 17.5 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF3449 PF11931.3 EWM22360.1 - 0.028 13.9 1.0 0.028 13.9 0.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3449) Rtf2 PF04641.7 EWM22360.1 - 0.11 11.6 2.8 0.16 11.1 1.9 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Ribosomal_L44 PF00935.14 EWM22360.1 - 0.14 12.1 1.4 0.89 9.6 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein L44 G-patch_2 PF12656.2 EWM22360.1 - 1.1 9.1 4.3 0.42 10.4 0.9 1.9 2 0 0 2 2 2 0 DExH-box splicing factor binding site PDCD2_C PF04194.8 EWM22361.1 - 1.7e-34 118.8 0.0 1.1e-31 109.7 0.0 2.4 2 0 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain zf-MYND PF01753.13 EWM22361.1 - 6e-09 35.6 8.8 6e-09 35.6 6.1 2.8 4 0 0 4 4 4 1 MYND finger TerY-C PF15616.1 EWM22361.1 - 0.11 12.4 6.5 2.2 8.2 0.0 3.0 3 1 0 3 3 3 0 TerY-C metal binding domain AOX PF01786.12 EWM22362.1 - 2e-37 128.6 3.1 2.8e-37 128.1 2.2 1.1 1 0 0 1 1 1 1 Alternative oxidase Peptidase_M16_C PF05193.16 EWM22363.1 - 1.3e-32 112.9 0.0 1.7e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EWM22363.1 - 0.00039 20.1 0.0 0.00062 19.5 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) FMO-like PF00743.14 EWM22364.1 - 9.8e-49 165.9 0.0 5.9e-20 70.9 0.0 3.7 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EWM22364.1 - 1.9e-13 50.9 0.0 3.8e-13 49.9 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EWM22364.1 - 3.1e-07 30.3 0.0 1.2e-06 28.4 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EWM22364.1 - 9.4e-05 21.6 0.0 0.00097 18.2 0.0 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 EWM22364.1 - 0.00027 20.7 0.0 0.0082 15.9 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EWM22364.1 - 0.00086 18.4 0.2 0.0016 17.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EWM22364.1 - 0.0016 18.3 0.0 0.31 10.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EWM22364.1 - 0.0024 16.4 0.3 0.0035 15.8 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein 2-Hacid_dh_C PF02826.14 EWM22364.1 - 0.011 14.8 0.0 2.7 7.1 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EWM22364.1 - 0.017 14.6 0.1 0.033 13.7 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 EWM22364.1 - 0.018 13.9 0.3 0.027 13.3 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 EWM22364.1 - 0.02 15.2 0.9 1.8 9.0 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EWM22364.1 - 0.033 13.8 1.9 0.77 9.3 0.3 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain LEA_2 PF03168.8 EWM22365.1 - 0.0047 17.2 0.0 0.0074 16.6 0.0 1.3 1 0 0 1 1 1 1 Late embryogenesis abundant protein PSI PF01437.20 EWM22365.1 - 0.095 12.8 12.9 0.22 11.7 8.9 1.7 1 0 0 1 1 1 0 Plexin repeat DUF3317 PF11779.3 EWM22365.1 - 2.2 7.7 4.6 2.2 7.7 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3317) DAO PF01266.19 EWM22366.1 - 1.8e-06 27.1 0.1 0.04 12.8 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EWM22366.1 - 1.7e-05 23.9 0.0 4.5e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.9 EWM22366.1 - 2.9e-05 22.8 0.1 0.00095 17.8 0.0 2.4 2 1 0 2 2 2 1 Tryptophan halogenase FAD_binding_3 PF01494.14 EWM22366.1 - 0.0094 15.0 0.1 0.036 13.1 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EWM22366.1 - 0.044 12.8 0.4 0.13 11.3 0.3 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EWM22366.1 - 0.098 12.6 0.0 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 EWM22366.1 - 0.21 11.1 0.0 0.34 10.5 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3150 PF11348.3 EWM22366.1 - 0.23 10.5 0.0 0.36 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) GST_N_2 PF13409.1 EWM22367.1 - 2.3e-12 46.7 0.0 5.4e-12 45.5 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EWM22367.1 - 2.5e-12 46.8 0.0 6.3e-12 45.5 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EWM22367.1 - 4.1e-07 29.8 0.1 8.5e-07 28.7 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EWM22367.1 - 4.9e-05 23.4 0.0 9.6e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EWM22367.1 - 0.012 15.5 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Tom37 PF10568.4 EWM22367.1 - 0.016 15.4 0.1 0.044 14.0 0.0 1.8 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein GST_C_3 PF14497.1 EWM22367.1 - 0.018 15.5 0.0 0.03 14.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain IPP-2 PF04979.9 EWM22368.1 - 1.3e-07 31.8 15.0 8.8e-05 22.7 0.1 2.5 2 1 0 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) Pro_isomerase PF00160.16 EWM22369.1 - 8.3e-45 152.7 0.0 8.3e-45 152.7 0.0 1.7 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SYF2 PF08231.7 EWM22369.1 - 8.2e-32 110.4 1.4 8.2e-32 110.4 1.0 2.2 2 0 0 2 2 2 1 SYF2 splicing factor Daxx PF03344.10 EWM22369.1 - 4.1 5.7 19.4 5.8 5.2 13.5 1.2 1 0 0 1 1 1 0 Daxx Family SRP_SPB PF02978.14 EWM22370.1 - 1.7e-08 34.6 0.9 4.7e-07 30.0 0.0 2.4 1 1 1 2 2 2 1 Signal peptide binding domain DUF3236 PF11576.3 EWM22370.1 - 0.033 13.6 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) zf-CDGSH PF09360.5 EWM22371.1 - 2.6e-12 46.3 0.1 4.8e-12 45.4 0.1 1.5 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type Gly-rich_Ago1 PF12764.2 EWM22372.1 - 0.66 10.6 4.7 1.1 9.9 3.2 1.5 1 0 0 1 1 1 0 Glycine-rich region of argonaut FXR1P_C PF12235.3 EWM22372.1 - 1.3 9.1 9.5 1.9 8.5 6.6 1.4 1 1 0 1 1 1 0 Fragile X-related 1 protein C terminal Pro_isomerase PF00160.16 EWM22373.1 - 7.4e-52 175.6 0.1 1.6e-51 174.5 0.1 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EWM22373.1 - 1.4e-22 78.7 0.2 3.1e-06 26.8 0.0 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat Gmad1 PF10647.4 EWM22373.1 - 0.014 14.8 0.0 1.3 8.3 0.0 3.0 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain OSCP PF00213.13 EWM22374.1 - 2.1e-24 86.2 0.3 2.8e-24 85.9 0.2 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF2470 PF10615.4 EWM22375.1 - 8.8e-17 61.1 0.0 1.9e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Suc_Fer-like PF06999.7 EWM22375.1 - 2.4e-09 37.5 0.0 5.5e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Sucrase/ferredoxin-like F-box-like PF12937.2 EWM22376.1 - 0.00039 20.0 0.0 0.00087 18.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EWM22376.1 - 0.00043 19.8 0.1 0.0014 18.2 0.1 1.9 1 0 0 1 1 1 1 F-box domain FlaC_arch PF05377.6 EWM22376.1 - 0.14 12.1 5.5 0.77 9.6 0.2 3.5 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Mito_carr PF00153.22 EWM22377.1 - 1.6e-52 175.1 0.0 1.3e-19 69.6 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.20 EWM22378.1 - 2.7e-75 252.8 0.0 3.4e-75 252.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM22378.1 - 6.9e-35 120.3 0.0 9.1e-35 119.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EWM22378.1 - 8e-06 25.7 0.1 0.028 14.1 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EWM22378.1 - 0.00084 18.4 0.0 0.0027 16.7 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EWM22378.1 - 0.024 13.9 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 EWM22378.1 - 0.044 12.5 0.0 0.079 11.7 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RE_R_Pab1 PF09522.5 EWM22378.1 - 0.091 12.7 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 R.Pab1 restriction endonuclease TCR PF03638.10 EWM22379.1 - 2.3e-26 91.3 45.0 3.8e-13 49.0 13.8 2.2 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain CCT PF06203.9 EWM22380.1 - 1.1e-16 60.1 8.2 1.8e-16 59.4 5.7 1.3 1 0 0 1 1 1 1 CCT motif NmrA PF05368.8 EWM22381.1 - 3.3e-26 91.9 0.0 5e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EWM22381.1 - 1.3e-09 38.3 0.1 3.4e-09 36.9 0.0 1.8 2 1 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 EWM22381.1 - 0.0031 16.2 0.0 0.0048 15.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EWM22381.1 - 0.033 13.6 0.0 0.12 11.8 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family UPF0118 PF01594.11 EWM22382.1 - 3.7e-27 95.1 14.5 3.7e-27 95.1 10.1 2.0 2 1 0 2 2 2 1 Domain of unknown function DUF20 Sec63 PF02889.11 EWM22383.1 - 4.7e-189 627.2 0.0 8.8e-102 340.5 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EWM22383.1 - 2.3e-42 144.3 0.1 7.8e-28 97.0 0.1 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 EWM22383.1 - 6.4e-10 39.1 0.0 5.4e-08 32.8 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EWM22383.1 - 1.1e-09 37.9 0.0 1e-08 34.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EWM22383.1 - 0.015 14.1 0.0 0.051 12.3 0.0 1.9 2 0 0 2 2 2 0 SNF2 family N-terminal domain Sigma54_activ_2 PF14532.1 EWM22383.1 - 0.027 14.5 0.0 14 5.7 0.0 4.2 5 0 0 5 5 5 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 EWM22383.1 - 0.038 13.3 0.1 2.7 7.3 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_11 PF13086.1 EWM22383.1 - 0.21 11.1 0.0 22 4.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain Nop14 PF04147.7 EWM22383.1 - 2.9 5.6 9.4 4.4 5.0 6.5 1.2 1 0 0 1 1 1 0 Nop14-like family RhoGAP PF00620.22 EWM22384.1 - 8.6e-31 106.5 0.0 1.5e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.12 EWM22384.1 - 8e-09 35.4 0.0 2.1e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 MyTH4 domain PH PF00169.24 EWM22384.1 - 0.0061 16.7 0.0 0.017 15.2 0.0 1.8 1 0 0 1 1 1 1 PH domain Myb_DNA-bind_6 PF13921.1 EWM22385.1 - 1.4e-28 98.7 6.7 2.4e-13 49.9 0.0 3.4 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EWM22385.1 - 6.2e-27 93.3 3.9 2.4e-10 40.2 0.0 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.3 EWM22385.1 - 0.011 15.5 0.3 3.4 7.6 0.1 3.0 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF3628 PF12300.3 EWM22385.1 - 0.066 13.2 18.7 1 9.3 3.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3628) Pkinase PF00069.20 EWM22386.1 - 2e-63 213.9 0.0 2.9e-63 213.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM22386.1 - 9.7e-32 110.0 0.0 1.5e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EWM22386.1 - 3.7e-06 27.3 0.6 1.1e-05 25.8 0.4 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.18 EWM22386.1 - 1.9e-05 24.5 0.0 0.00027 20.7 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EWM22386.1 - 2.5e-05 23.3 0.0 4.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EWM22386.1 - 0.02 14.2 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 EWM22386.1 - 0.17 10.9 0.0 0.39 9.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DENN PF02141.16 EWM22387.1 - 3.2e-45 154.1 2.7 5.7e-45 153.3 1.9 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 EWM22387.1 - 1.5e-12 47.2 0.9 3.4e-12 46.1 0.6 1.7 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 EWM22387.1 - 9.9e-10 38.3 0.1 2.2e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 dDENN domain DUF2464 PF10240.4 EWM22387.1 - 0.0054 16.1 1.9 0.034 13.4 0.0 3.0 3 1 1 4 4 4 2 Protein of unknown function (DUF2464) K_channel_TID PF07941.6 EWM22388.1 - 5.1 7.3 9.0 1.9 8.7 0.5 2.9 2 1 1 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain PIF1 PF05970.9 EWM22390.1 - 1.1e-37 129.8 0.2 5.8e-28 97.8 0.0 3.3 3 1 0 3 3 3 2 PIF1-like helicase AAA_30 PF13604.1 EWM22390.1 - 3.5e-11 43.0 0.0 1.6e-08 34.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EWM22390.1 - 1.4e-05 25.2 0.0 4.1e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EWM22390.1 - 0.00083 19.0 0.1 0.013 15.2 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EWM22390.1 - 0.0018 18.2 0.4 0.0046 16.9 0.1 1.8 2 0 0 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.21 EWM22390.1 - 0.008 15.6 0.0 0.26 10.7 0.0 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain T2SE PF00437.15 EWM22390.1 - 0.085 11.7 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activ_2 PF14532.1 EWM22390.1 - 0.16 12.0 0.1 5.2 7.1 0.0 2.7 2 1 0 2 2 2 0 Sigma-54 interaction domain DUF258 PF03193.11 EWM22390.1 - 0.16 11.1 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DEAD PF00270.24 EWM22390.1 - 0.17 11.3 0.0 20 4.6 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_11 PF13086.1 EWM22390.1 - 0.26 10.8 0.2 5.3 6.5 0.0 2.5 3 0 0 3 3 3 0 AAA domain Pro_isomerase PF00160.16 EWM22394.1 - 3.3e-45 154.0 0.1 3.9e-45 153.8 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Amidohydro_1 PF01979.15 EWM22395.1 - 1e-28 100.9 0.0 1.3e-28 100.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.9 EWM22395.1 - 4.6e-06 26.3 0.5 6.1e-06 25.9 0.3 1.3 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EWM22395.1 - 1.6e-05 25.0 2.7 5.6e-05 23.3 1.8 2.0 1 1 0 1 1 1 1 Amidohydrolase SNF2_N PF00176.18 EWM22396.1 - 1.4e-57 194.7 0.0 2.1e-57 194.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EWM22396.1 - 1.6e-10 40.7 0.0 3.5e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RanBP PF00641.13 EWM22396.1 - 2e-06 26.7 4.7 5e-06 25.4 3.2 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others ResIII PF04851.10 EWM22396.1 - 0.00018 21.3 0.1 0.00087 19.1 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 EWM22396.1 - 0.00058 18.7 2.1 0.0028 16.5 0.0 3.0 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Rad1 PF02144.11 EWM22397.1 - 0.00034 19.4 0.0 0.00045 19.0 0.0 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Peptidase_M15_2 PF05951.8 EWM22397.1 - 0.095 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) IspD PF01128.14 EWM22399.1 - 6.6e-57 192.5 0.0 7.8e-57 192.3 0.0 1.0 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transf_3 PF12804.2 EWM22399.1 - 8.2e-10 38.9 0.0 1e-09 38.6 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 EWM22399.1 - 0.085 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyl transferase NARP1 PF12569.3 EWM22400.1 - 0.45 9.2 2.3 0.53 8.9 1.6 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Methyltransf_16 PF10294.4 EWM22401.1 - 4.7e-25 88.0 0.0 6.1e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EWM22401.1 - 6.7e-07 28.8 0.0 1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EWM22401.1 - 2.3e-06 28.1 0.1 4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EWM22401.1 - 0.00013 21.1 0.0 0.00019 20.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 EWM22401.1 - 0.00014 21.4 0.0 0.00021 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM22401.1 - 0.00043 20.7 0.0 0.00072 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM22401.1 - 0.007 16.0 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM22401.1 - 0.056 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Rep_fac-A_C PF08646.5 EWM22402.1 - 2.2e-43 147.4 1.6 2.8e-42 143.8 0.4 2.3 2 0 0 2 2 2 1 Replication factor-A C terminal domain Rep-A_N PF04057.7 EWM22402.1 - 5.5e-27 93.5 0.0 1e-26 92.6 0.0 1.5 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 EWM22402.1 - 8e-14 51.2 0.1 8e-09 35.2 0.0 3.4 3 1 0 3 3 3 2 OB-fold nucleic acid binding domain Flg_bbr_C PF06429.8 EWM22402.1 - 0.08 12.8 0.6 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 Flagellar basal body rod FlgEFG protein C-terminal WD40 PF00400.27 EWM22403.1 - 8.2e-16 57.2 2.0 1.3e-05 24.8 0.2 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat AARP2CN PF08142.7 EWM22403.1 - 0.12 11.8 0.0 9.5 5.8 0.0 2.4 2 0 0 2 2 2 0 AARP2CN (NUC121) domain Tub PF01167.13 EWM22404.1 - 3.8e-07 29.3 0.0 6.5e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Tub family FF PF01846.14 EWM22405.1 - 7.3e-30 102.6 12.1 7.8e-10 38.5 0.5 5.6 6 0 0 6 6 6 4 FF domain WW PF00397.21 EWM22405.1 - 3.4e-07 30.0 13.7 3.1e-06 26.9 1.1 2.9 3 0 0 3 3 3 2 WW domain FF PF01846.14 EWM22406.1 - 8e-30 102.5 12.1 8.1e-10 38.5 0.5 5.6 6 0 0 6 6 6 4 FF domain WW PF00397.21 EWM22406.1 - 3.6e-07 29.9 13.7 3.2e-06 26.8 1.1 2.9 3 0 0 3 3 3 2 WW domain TLC PF03219.9 EWM22407.1 - 4.6e-144 480.5 16.5 5.7e-144 480.2 11.5 1.1 1 0 0 1 1 1 1 TLC ATP/ADP transporter Ldr_toxin PF13940.1 EWM22407.1 - 0.31 10.8 4.3 1.8 8.4 0.3 3.1 3 0 0 3 3 3 0 Toxin Ldr, type I toxin-antitoxin system Proteasome PF00227.21 EWM22408.1 - 3.6e-55 186.2 0.6 4.5e-55 185.8 0.4 1.1 1 0 0 1 1 1 1 Proteasome subunit UPF0546 PF10639.4 EWM22408.1 - 8.7e-21 73.8 0.0 1.7e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 Proteasome_A_N PF10584.4 EWM22408.1 - 3.5e-13 48.6 0.0 6.9e-13 47.6 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature EamA PF00892.15 EWM22408.1 - 0.02 14.9 3.8 0.031 14.3 2.6 1.2 1 0 0 1 1 1 0 EamA-like transporter family Asp_Arg_Hydrox PF05118.10 EWM22409.1 - 3.9e-12 46.3 0.1 6.3e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase WD40 PF00400.27 EWM22410.1 - 1.8e-13 49.7 13.5 0.00053 19.7 0.0 10.5 11 0 0 11 11 11 2 WD domain, G-beta repeat PQQ_3 PF13570.1 EWM22410.1 - 0.00014 22.0 7.3 30 5.0 0.0 7.8 9 0 0 9 9 9 0 PQQ-like domain Nbas_N PF15492.1 EWM22410.1 - 0.00025 20.2 0.1 0.012 14.7 0.0 3.7 5 0 0 5 5 5 1 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.1 EWM22410.1 - 0.0015 18.0 0.1 0.047 13.1 0.0 3.2 3 1 0 3 3 3 1 PQQ-like domain PQQ PF01011.16 EWM22410.1 - 0.046 13.2 0.2 3 7.5 0.0 3.5 3 0 0 3 3 3 0 PQQ enzyme repeat DUF3312 PF11768.3 EWM22410.1 - 0.072 11.3 0.0 6.5 4.8 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3312) ACPS PF01648.15 EWM22411.1 - 1.2e-12 47.6 0.0 7e-12 45.1 0.0 2.2 3 0 0 3 3 3 1 4'-phosphopantetheinyl transferase superfamily tRNA-synt_2b PF00587.20 EWM22412.1 - 2.8e-30 105.1 0.0 4.8e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS PF00458.15 EWM22412.1 - 2.8e-27 94.1 14.3 5.2e-14 51.6 2.0 3.3 3 0 0 3 3 3 2 WHEP-TRS domain Seryl_tRNA_N PF02403.17 EWM22412.1 - 0.046 13.7 0.6 0.046 13.7 0.4 3.2 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Phage_GP20 PF06810.6 EWM22412.1 - 0.34 10.3 4.1 8.8 5.7 0.2 3.0 3 0 0 3 3 3 0 Phage minor structural protein GP20 SR-25 PF10500.4 EWM22413.1 - 2.8e-05 23.6 12.7 4.9e-05 22.9 8.8 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Adaptin_binding PF10199.4 EWM22413.1 - 0.011 15.9 3.9 0.019 15.2 2.7 1.4 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 SAP PF02037.22 EWM22413.1 - 0.016 14.7 0.3 2.1 7.9 0.0 2.4 2 0 0 2 2 2 0 SAP domain Bul1_N PF04425.7 EWM22413.1 - 0.047 12.2 1.7 0.067 11.7 1.2 1.1 1 0 0 1 1 1 0 Bul1 N terminus Macoilin PF09726.4 EWM22413.1 - 0.06 11.6 8.5 0.078 11.2 5.9 1.2 1 0 0 1 1 1 0 Transmembrane protein CAF-1_p150 PF11600.3 EWM22413.1 - 0.09 12.1 10.9 0.18 11.1 7.6 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Polyoma_lg_T_C PF06431.6 EWM22413.1 - 0.1 11.2 0.7 0.14 10.7 0.5 1.1 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus Armet PF10208.4 EWM22413.1 - 0.15 11.7 0.1 0.64 9.6 0.1 1.8 2 0 0 2 2 2 0 Degradation arginine-rich protein for mis-folding Sec3_C PF09763.4 EWM22413.1 - 0.17 9.9 3.7 0.23 9.5 2.6 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec3 RAP1 PF07218.6 EWM22413.1 - 0.24 9.4 8.5 0.31 9.0 5.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF2217 PF10265.4 EWM22413.1 - 0.46 9.1 5.8 0.65 8.7 4.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Apt1 PF10351.4 EWM22413.1 - 1.1 8.0 8.9 1.4 7.6 6.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF508 PF04370.7 EWM22413.1 - 2.7 7.5 11.2 4.6 6.8 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF508) AF-4 PF05110.8 EWM22413.1 - 4 5.1 21.2 5.8 4.6 14.7 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Tmemb_cc2 PF10267.4 EWM22413.1 - 5.4 5.4 14.5 9.5 4.6 9.9 1.5 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein SSP160 PF06933.6 EWM22413.1 - 5.8 4.7 13.5 7.7 4.3 9.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TraG-D_C PF12696.2 EWM22413.1 - 6.2 6.7 7.6 12 5.7 5.2 1.5 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG DUF755 PF05501.6 EWM22413.1 - 6.8 6.7 22.0 15 5.6 15.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF755) RNA_polI_A34 PF08208.6 EWM22414.1 - 2.6e-08 33.8 1.8 4.4e-05 23.2 0.9 2.8 2 1 0 2 2 2 2 DNA-directed RNA polymerase I subunit RPA34.5 Meth_synt_1 PF08267.7 EWM22415.1 - 3.7e-82 276.0 0.0 2.3e-79 266.9 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain Meth_synt_2 PF01717.13 EWM22415.1 - 2.4e-65 220.6 0.0 8.8e-59 199.0 0.0 3.5 4 0 0 4 4 4 3 Cobalamin-independent synthase, Catalytic domain Meth_synt_2 PF01717.13 EWM22416.1 - 1.6e-138 461.1 0.0 3.8e-132 440.1 0.0 3.4 3 0 0 3 3 3 3 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EWM22416.1 - 8.2e-89 297.9 0.0 3e-79 266.5 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain PPR_3 PF13812.1 EWM22417.1 - 8.8e-23 78.6 1.7 0.00089 19.3 0.0 6.4 6 0 0 6 6 6 6 Pentatricopeptide repeat domain PPR_2 PF13041.1 EWM22417.1 - 3.6e-20 71.6 0.0 8.4e-07 28.8 0.0 5.2 3 2 2 5 5 5 4 PPR repeat family PPR PF01535.15 EWM22417.1 - 1.4e-15 56.1 12.1 0.0044 16.8 0.0 6.3 6 0 0 6 6 6 4 PPR repeat PPR_1 PF12854.2 EWM22417.1 - 4e-07 29.3 0.0 0.64 9.5 0.0 5.3 5 0 0 5 5 5 1 PPR repeat TilS PF09179.6 EWM22417.1 - 0.036 14.0 0.0 0.083 12.9 0.0 1.6 1 0 0 1 1 1 0 TilS substrate binding domain ECSIT PF06239.6 EWM22417.1 - 0.049 12.4 0.0 0.24 10.2 0.0 2.0 2 0 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway HRM PF02793.17 EWM22417.1 - 0.083 12.9 1.1 31 4.6 0.0 3.5 3 1 0 3 3 3 0 Hormone receptor domain DUF2597 PF10772.4 EWM22417.1 - 0.1 12.5 0.0 0.55 10.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2597) TPR_14 PF13428.1 EWM22417.1 - 0.12 13.1 0.7 32 5.5 0.0 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat Radical_SAM PF04055.16 EWM22418.1 - 3.5e-31 108.6 0.0 8.5e-31 107.3 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.15 EWM22418.1 - 2.5e-27 94.5 0.2 7.1e-27 93.1 0.2 1.8 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Rotamase_3 PF13616.1 EWM22418.1 - 4.8e-11 42.9 0.0 1.1e-10 41.8 0.0 1.6 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 EWM22418.1 - 6.9e-07 29.9 0.0 4.9e-06 27.1 0.0 2.4 2 0 0 2 2 2 1 PPIC-type PPIASE domain TRAM PF01938.15 EWM22418.1 - 1.3e-06 28.0 0.1 2.9e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 TRAM domain Swi3 PF07962.7 EWM22418.1 - 0.0096 15.5 0.0 0.029 14.0 0.0 1.8 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Fer4_12 PF13353.1 EWM22418.1 - 0.059 13.4 0.0 0.2 11.7 0.0 1.8 2 0 0 2 2 2 0 4Fe-4S single cluster domain PX PF00787.19 EWM22419.1 - 2.8e-11 43.1 0.0 5.1e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 PX domain PDZ PF00595.19 EWM22419.1 - 0.016 15.3 0.1 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) FAIM1 PF06905.8 EWM22419.1 - 0.017 14.2 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Fas apoptotic inhibitory molecule (FAIM1) PDZ_2 PF13180.1 EWM22419.1 - 0.049 13.5 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 PDZ domain Methyltransf_11 PF08241.7 EWM22420.1 - 2.4e-25 88.8 0.0 4.2e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM22420.1 - 1.3e-22 80.0 0.0 2e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM22420.1 - 1.6e-18 66.9 0.1 3.6e-18 65.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM22420.1 - 1.6e-15 57.3 0.0 3.6e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM22420.1 - 6.9e-15 55.2 0.0 1.4e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EWM22420.1 - 2.4e-14 53.0 0.0 4e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EWM22420.1 - 7.3e-14 52.2 0.0 1.5e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EWM22420.1 - 1.3e-12 47.4 0.0 1.8e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EWM22420.1 - 8.9e-10 38.6 0.0 1.9e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EWM22420.1 - 1.5e-07 31.1 0.0 2.3e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_29 PF03141.11 EWM22420.1 - 5.2e-07 28.3 0.0 7.4e-07 27.8 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.9 EWM22420.1 - 1.9e-05 24.1 0.0 4.2e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.7 EWM22420.1 - 3e-05 23.4 0.0 4.7e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase NodS PF05401.6 EWM22420.1 - 8.5e-05 22.0 0.0 0.00013 21.3 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) FtsJ PF01728.14 EWM22420.1 - 0.00011 22.2 0.0 0.00042 20.3 0.0 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase MetW PF07021.7 EWM22420.1 - 0.00029 20.2 0.0 0.00053 19.4 0.0 1.4 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW TehB PF03848.9 EWM22420.1 - 0.00066 18.9 0.0 0.0094 15.1 0.0 2.3 2 0 0 2 2 2 1 Tellurite resistance protein TehB ADH_zinc_N PF00107.21 EWM22420.1 - 0.00074 19.0 0.0 0.0017 17.8 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_4 PF02390.12 EWM22420.1 - 0.00089 18.3 0.0 0.015 14.3 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase PrmA PF06325.8 EWM22420.1 - 0.002 17.3 0.0 0.0063 15.6 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 EWM22420.1 - 0.0028 17.3 0.0 0.0044 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EWM22420.1 - 0.0073 17.1 0.0 0.014 16.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EWM22420.1 - 0.011 15.4 0.0 0.027 14.0 0.0 1.6 1 1 0 1 1 1 0 Hypothetical methyltransferase NAS PF03059.11 EWM22420.1 - 0.029 13.5 0.0 0.038 13.1 0.0 1.1 1 0 0 1 1 1 0 Nicotianamine synthase protein Rsm22 PF09243.5 EWM22420.1 - 0.035 13.1 0.0 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 DREV PF05219.7 EWM22420.1 - 0.071 11.9 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Hemerythrin PF01814.18 EWM22421.1 - 1.2e-06 28.6 0.2 0.0054 16.8 0.0 2.9 3 0 0 3 3 3 2 Hemerythrin HHE cation binding domain TMF_TATA_bd PF12325.3 EWM22421.1 - 0.096 12.4 0.2 0.39 10.4 0.0 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Sigma70_r4 PF04545.11 EWM22422.1 - 6.3e-07 28.6 0.7 1.8e-06 27.1 0.1 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r2 PF04542.9 EWM22422.1 - 4.2e-06 26.2 0.1 1.2e-05 24.7 0.1 1.8 1 0 0 1 1 1 1 Sigma-70 region 2 HTH_24 PF13412.1 EWM22422.1 - 0.042 13.2 0.0 9.7 5.6 0.0 2.7 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding GerE PF00196.14 EWM22422.1 - 0.091 12.0 0.0 0.47 9.8 0.0 2.1 2 1 0 2 2 2 0 Bacterial regulatory proteins, luxR family Sigma70_r4_2 PF08281.7 EWM22422.1 - 0.35 10.3 3.6 0.83 9.1 1.2 2.6 2 1 0 2 2 2 0 Sigma-70, region 4 Cupin_8 PF13621.1 EWM22423.1 - 3.3e-11 43.1 0.1 4.7e-11 42.6 0.0 1.4 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EWM22423.1 - 1.3e-07 31.2 0.1 8.5e-05 21.9 0.0 2.7 2 1 0 2 2 2 2 Cupin superfamily protein Cupin_2 PF07883.6 EWM22423.1 - 0.029 13.8 0.0 0.095 12.2 0.0 1.8 2 0 0 2 2 2 0 Cupin domain Pkinase PF00069.20 EWM22424.1 - 6.9e-64 215.4 0.0 9.5e-64 215.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM22424.1 - 1e-47 162.4 0.0 1.4e-47 161.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.3 EWM22424.1 - 2.6e-12 46.4 0.2 5e-12 45.5 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) APH PF01636.18 EWM22424.1 - 0.0023 17.7 0.3 0.0023 17.7 0.2 4.5 3 1 1 4 4 4 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EWM22424.1 - 0.0085 14.9 0.0 0.84 8.3 0.0 2.2 2 0 0 2 2 2 2 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 EWM22424.1 - 0.0099 14.8 0.0 0.029 13.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like PHF5 PF03660.9 EWM22425.1 - 5.3e-49 164.7 11.7 6e-49 164.5 8.1 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.8 EWM22425.1 - 0.28 8.8 6.3 0.29 8.7 4.4 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.2 EWM22425.1 - 1.5 8.7 14.5 1.1 9.1 1.7 2.8 1 1 1 2 2 2 0 Double zinc ribbon PHD PF00628.24 EWM22425.1 - 2.1 8.0 15.9 0.055 13.1 4.7 2.7 1 1 2 3 3 3 0 PHD-finger DUF3716 PF12511.3 EWM22425.1 - 9.6 5.9 12.9 2.5 7.7 5.5 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3716) fn3 PF00041.16 EWM22427.1 - 7.3e-09 35.6 0.0 9e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Fibronectin type III domain Interfer-bind PF09294.5 EWM22427.1 - 0.0084 16.1 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III DAO PF01266.19 EWM22428.1 - 2.7e-53 181.1 0.6 3.1e-53 180.9 0.4 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EWM22428.1 - 4.2e-05 23.4 0.2 8.9e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EWM22428.1 - 0.0003 20.8 0.0 0.00045 20.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EWM22428.1 - 0.00049 20.4 0.5 0.0016 18.8 0.4 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EWM22428.1 - 0.0084 15.0 0.2 0.05 12.5 0.1 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 EWM22428.1 - 0.0086 15.1 0.7 0.0086 15.1 0.5 1.5 2 0 0 2 2 2 1 FAD binding domain TrkA_N PF02254.13 EWM22428.1 - 0.016 15.2 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain adh_short PF00106.20 EWM22428.1 - 0.025 14.4 0.7 0.12 12.2 0.3 2.0 2 0 0 2 2 2 0 short chain dehydrogenase FAD_oxidored PF12831.2 EWM22428.1 - 0.027 13.5 2.1 0.52 9.3 1.5 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EWM22428.1 - 0.047 13.5 0.1 0.079 12.8 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EWM22428.1 - 0.053 12.6 0.3 0.12 11.4 0.2 1.6 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EWM22428.1 - 0.055 11.9 0.4 0.083 11.3 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.19 EWM22428.1 - 0.098 11.4 0.5 0.18 10.6 0.4 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_Gly3P_dh_N PF01210.18 EWM22428.1 - 0.15 11.7 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.1 EWM22428.1 - 0.22 11.7 0.7 2.5 8.4 0.5 2.4 2 1 0 2 2 2 0 Putative NAD(P)-binding Beta-lactamase PF00144.19 EWM22429.1 - 9.2e-56 189.2 0.1 1.5e-55 188.5 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase IF-2B PF01008.12 EWM22430.1 - 2.2e-73 246.7 0.0 2.6e-73 246.4 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family PEP-utilizers PF00391.18 EWM22430.1 - 0.036 13.6 0.2 0.14 11.7 0.0 2.0 2 0 0 2 2 2 0 PEP-utilising enzyme, mobile domain His_Phos_1 PF00300.17 EWM22431.1 - 9.3e-43 146.0 0.0 1.2e-42 145.6 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) F-box-like PF12937.2 EWM22432.1 - 0.00051 19.7 0.0 0.0015 18.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like PQQ_3 PF13570.1 EWM22432.1 - 0.0012 19.0 1.1 0.22 11.8 0.0 3.4 3 0 0 3 3 3 1 PQQ-like domain WD40 PF00400.27 EWM22432.1 - 0.069 13.0 12.1 0.15 12.0 1.2 4.8 5 0 0 5 5 5 0 WD domain, G-beta repeat F-box PF00646.28 EWM22432.1 - 0.69 9.6 3.4 0.74 9.5 0.0 2.8 3 1 0 3 3 3 0 F-box domain Lipase_3 PF01764.20 EWM22433.1 - 3.9e-13 49.2 0.0 6.3e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EWM22433.1 - 0.0059 16.3 0.1 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EWM22433.1 - 0.007 16.2 0.1 0.018 14.9 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 EWM22433.1 - 0.16 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Asp PF00026.18 EWM22434.1 - 9.7e-82 274.7 0.0 1.2e-81 274.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EWM22434.1 - 1.3e-08 34.9 0.1 4.8e-08 33.1 0.1 1.8 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EWM22434.1 - 0.00016 21.2 0.0 0.0014 18.2 0.0 2.1 1 1 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EWM22434.1 - 0.052 14.0 0.0 1.3 9.6 0.0 2.7 2 1 0 2 2 2 0 Aspartyl protease UCH PF00443.24 EWM22435.1 - 3.2e-47 160.8 0.0 5.1e-47 160.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EWM22435.1 - 4e-16 59.3 0.0 6.8e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Sporozoite_P67 PF05642.6 EWM22435.1 - 0.74 7.6 0.7 1.6 6.4 0.5 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Adeno_terminal PF02459.10 EWM22435.1 - 2.4 6.2 1.5 5.1 5.1 1.1 1.5 1 0 0 1 1 1 0 Adenoviral DNA terminal protein KOW PF00467.24 EWM22436.1 - 4.9e-06 26.0 3.2 4.9e-06 26.0 2.2 2.1 3 0 0 3 3 3 1 KOW motif DUF1021 PF06257.6 EWM22436.1 - 0.12 12.1 2.2 0.5 10.0 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1021) RRM_1 PF00076.17 EWM22437.1 - 7.6e-55 182.4 0.7 4.1e-15 55.1 0.0 6.0 6 0 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM22437.1 - 9.1e-46 153.7 1.3 6e-12 45.3 0.0 6.6 5 1 1 6 6 6 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM22437.1 - 1.3e-22 79.4 0.1 3.8e-06 26.6 0.0 5.5 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EWM22437.1 - 5.4e-06 26.0 1.1 0.00018 21.1 0.1 3.8 4 0 0 4 4 4 1 Limkain b1 Nup35_RRM_2 PF14605.1 EWM22437.1 - 0.05 13.3 0.0 0.62 9.8 0.0 2.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif PPTA PF01239.17 EWM22438.1 - 2.8e-40 133.9 14.5 2.7e-11 42.2 0.1 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DNApol3-delta_C PF09115.5 EWM22438.1 - 0.11 12.5 0.9 0.28 11.2 0.1 2.0 2 0 0 2 2 2 0 DNA polymerase III, delta subunit, C terminal DUF2353 PF09789.4 EWM22438.1 - 0.75 8.9 5.9 0.24 10.6 1.7 1.9 2 1 1 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) Peptidase_M16_C PF05193.16 EWM22439.1 - 2.4e-32 112.0 0.0 3.7e-32 111.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EWM22439.1 - 1.1e-23 83.6 0.0 2e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Str_synth PF03088.11 EWM22440.1 - 3.9e-07 30.0 0.0 1e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Strictosidine synthase AAA PF00004.24 EWM22441.1 - 7e-40 136.2 0.0 1.6e-39 135.0 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.13 EWM22441.1 - 7.5e-12 44.9 2.3 1.6e-11 43.8 1.6 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 EWM22441.1 - 2.8e-06 28.1 0.0 6.9e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EWM22441.1 - 3.3e-06 27.2 2.4 2.7e-05 24.2 0.2 2.8 3 1 0 3 3 1 1 AAA domain RuvB_N PF05496.7 EWM22441.1 - 6.6e-06 25.3 0.0 1.5e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EWM22441.1 - 9.5e-05 21.2 0.0 0.00015 20.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 EWM22441.1 - 0.00022 20.7 0.7 0.12 11.7 0.1 2.4 1 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EWM22441.1 - 0.00036 20.2 0.1 0.0014 18.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EWM22441.1 - 0.00086 18.7 0.0 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 EWM22441.1 - 0.00087 19.2 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EWM22441.1 - 0.0011 18.6 0.1 0.0035 17.0 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EWM22441.1 - 0.0014 18.6 4.6 0.0039 17.1 0.1 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_33 PF13671.1 EWM22441.1 - 0.0016 18.3 0.0 0.0036 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Vps4_C PF09336.5 EWM22441.1 - 0.004 17.0 0.0 0.0089 15.8 0.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_18 PF13238.1 EWM22441.1 - 0.007 16.6 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EWM22441.1 - 0.0077 15.1 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 EWM22441.1 - 0.0085 16.0 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EWM22441.1 - 0.01 15.7 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EWM22441.1 - 0.012 14.7 0.1 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 EWM22441.1 - 0.015 15.0 0.0 23 4.6 0.0 3.2 3 0 0 3 3 3 0 NTPase AAA_24 PF13479.1 EWM22441.1 - 0.027 14.0 0.1 0.1 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 EWM22441.1 - 0.028 13.9 0.1 0.071 12.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain TPR_5 PF12688.2 EWM22441.1 - 0.036 14.0 0.4 0.081 12.9 0.3 1.5 1 0 0 1 1 1 0 Tetratrico peptide repeat KaiC PF06745.8 EWM22441.1 - 0.047 12.7 0.4 1.2 8.1 0.0 2.2 1 1 1 2 2 2 0 KaiC PhoH PF02562.11 EWM22441.1 - 0.059 12.5 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Zeta_toxin PF06414.7 EWM22441.1 - 0.071 12.2 0.0 0.13 11.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.7 EWM22441.1 - 0.075 12.6 0.3 1.1 8.8 0.1 2.4 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 EWM22441.1 - 0.1 12.8 0.0 0.22 11.6 0.0 1.7 1 1 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 EWM22441.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain RNase_P_p30 PF01876.11 EWM22442.1 - 8.9e-32 109.3 0.0 1.2e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 EutN_CcmL PF03319.8 EWM22442.1 - 0.13 12.6 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutN/carboxysome Tic22 PF04278.7 EWM22443.1 - 3.8e-27 95.2 0.0 4e-19 68.9 0.0 2.0 2 0 0 2 2 2 2 Tic22-like family FBPase PF00316.15 EWM22444.1 - 4.5e-117 390.4 0.0 5.5e-117 390.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Helicase_C PF00271.26 EWM22445.1 - 1.3e-16 60.2 0.1 3.6e-16 58.7 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.18 EWM22445.1 - 9.9e-16 57.6 0.1 3.2e-15 55.9 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EWM22445.1 - 1.8e-11 43.8 0.0 4.8e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EWM22445.1 - 1.5e-07 31.0 0.1 6.7e-07 28.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase T2SE PF00437.15 EWM22445.1 - 9.7e-05 21.3 0.0 0.00018 20.5 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein NACHT PF05729.7 EWM22445.1 - 0.0036 16.9 0.1 0.017 14.7 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 EWM22445.1 - 0.0055 16.4 0.1 0.016 14.9 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EWM22445.1 - 0.0076 16.3 0.1 0.039 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 EWM22445.1 - 0.072 12.3 0.0 0.69 9.1 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_11 PF13086.1 EWM22445.1 - 0.33 10.4 4.0 0.34 10.4 0.0 2.6 2 1 0 2 2 2 0 AAA domain Glyco_hydro_47 PF01532.15 EWM22446.1 - 1.8e-128 429.0 0.0 6.4e-128 427.2 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 Cpn60_TCP1 PF00118.19 EWM22447.1 - 7.1e-137 456.9 4.1 8e-137 456.7 2.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family EAP30 PF04157.11 EWM22448.1 - 1.2e-48 165.1 0.0 1.5e-48 164.8 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 EWM22448.1 - 4.1e-11 42.5 0.0 6.9e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 DUF387 PF04079.11 EWM22451.1 - 0.036 13.4 0.0 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 Putative transcriptional regulators (Ypuh-like) SASRP1 PF15160.1 EWM22452.1 - 0.053 12.7 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated serine-rich protein 1 DUF1083 PF06452.6 EWM22453.1 - 1.1e-06 28.6 1.6 1.8e-06 27.9 1.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1083) S1 PF00575.18 EWM22454.1 - 2.5e-19 69.1 0.1 4.8e-09 36.1 0.0 2.7 2 1 0 2 2 2 2 S1 RNA binding domain AAA PF00004.24 EWM22455.1 - 1.1e-42 145.3 0.2 3.8e-42 143.6 0.0 2.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EWM22455.1 - 8.7e-07 29.0 0.0 2.5e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EWM22455.1 - 9.4e-07 28.6 0.1 4.1e-06 26.5 0.0 2.2 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EWM22455.1 - 8e-06 25.9 0.0 3.3e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EWM22455.1 - 1.8e-05 24.8 0.3 0.00071 19.7 0.0 3.0 3 1 0 3 3 2 1 AAA domain AAA_17 PF13207.1 EWM22455.1 - 0.0001 23.1 0.1 0.00031 21.5 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EWM22455.1 - 0.00012 21.8 1.1 0.00021 20.9 0.1 2.0 2 0 0 2 2 1 1 Part of AAA domain RuvB_N PF05496.7 EWM22455.1 - 0.00012 21.1 0.0 0.00023 20.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EWM22455.1 - 0.00052 19.4 0.0 0.00098 18.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 EWM22455.1 - 0.0012 18.7 0.0 0.0041 16.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.7 EWM22455.1 - 0.0032 16.6 0.0 0.0085 15.2 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.1 EWM22455.1 - 0.0039 17.1 0.0 0.0085 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EWM22455.1 - 0.004 17.0 0.0 0.0083 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 EWM22455.1 - 0.0041 16.9 0.0 1.9 8.2 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TIP49 PF06068.8 EWM22455.1 - 0.0047 15.6 0.0 0.0083 14.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus PhoH PF02562.11 EWM22455.1 - 0.0049 16.1 0.0 0.089 12.0 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_3 PF07726.6 EWM22455.1 - 0.005 16.4 0.0 0.014 14.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 EWM22455.1 - 0.0067 15.6 0.1 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EWM22455.1 - 0.0074 16.5 0.1 0.038 14.2 0.0 2.2 2 1 1 3 3 2 1 AAA domain Sigma54_activat PF00158.21 EWM22455.1 - 0.0075 15.7 0.0 0.063 12.7 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EWM22455.1 - 0.012 15.6 0.0 0.082 12.9 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 EWM22455.1 - 0.013 15.0 0.2 0.044 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF2072 PF09845.4 EWM22455.1 - 0.014 15.3 0.3 0.028 14.3 0.2 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) RNA_helicase PF00910.17 EWM22455.1 - 0.023 14.8 0.0 0.046 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 EWM22455.1 - 0.023 14.0 0.2 0.089 12.1 0.0 1.9 1 1 1 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 EWM22455.1 - 0.034 13.0 0.0 0.073 11.9 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF815 PF05673.8 EWM22455.1 - 0.036 12.9 0.0 0.064 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Seryl_tRNA_N PF02403.17 EWM22455.1 - 0.051 13.5 0.0 0.18 11.7 0.0 1.9 2 0 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain HR1 PF02185.11 EWM22455.1 - 0.066 12.9 0.5 0.16 11.7 0.4 1.6 1 0 0 1 1 1 0 Hr1 repeat KaiC PF06745.8 EWM22455.1 - 0.069 12.2 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 KaiC Cyclin_N PF00134.18 EWM22456.1 - 1.5e-14 53.6 0.1 2.4e-13 49.7 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain HSP70 PF00012.15 EWM22457.1 - 3.2e-263 874.1 12.9 3.6e-263 873.9 8.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EWM22457.1 - 2.9e-17 62.2 1.1 4.3e-16 58.4 0.3 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 EWM22457.1 - 0.0017 17.2 0.4 0.18 10.6 0.1 2.7 2 1 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 EWM22457.1 - 0.0018 17.4 1.7 0.09 11.8 0.0 3.1 2 1 0 3 3 3 1 Hydantoinase/oxoprolinase FGGY_C PF02782.11 EWM22457.1 - 0.0028 17.2 0.0 0.009 15.6 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EWM22457.1 - 0.035 13.9 2.0 0.96 9.3 0.1 3.4 2 1 0 2 2 2 0 Cell division protein FtsA Pox_A_type_inc PF04508.7 EWM22457.1 - 0.34 10.7 2.3 16 5.5 0.1 2.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat OmpH PF03938.9 EWM22457.1 - 2.1 8.2 8.9 0.97 9.3 3.1 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) SPOUT_MTase PF02590.12 EWM22458.1 - 3.3e-29 101.6 0.0 4.1e-28 98.0 0.0 2.1 1 1 0 1 1 1 1 Predicted SPOUT methyltransferase Mo25 PF08569.6 EWM22460.1 - 4.5e-111 371.1 0.5 6.9e-111 370.5 0.4 1.2 1 0 0 1 1 1 1 Mo25-like HEAT_2 PF13646.1 EWM22460.1 - 0.028 14.6 0.0 0.23 11.7 0.0 2.5 2 1 1 3 3 3 0 HEAT repeats Arm PF00514.18 EWM22460.1 - 0.12 12.1 0.0 48 3.9 0.0 3.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF601 PF04642.7 EWM22460.1 - 7.9 5.7 7.3 13 5.0 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF601 Mo25 PF08569.6 EWM22461.1 - 4.7e-111 371.0 0.4 7e-111 370.4 0.3 1.2 1 0 0 1 1 1 1 Mo25-like HEAT_2 PF13646.1 EWM22461.1 - 0.035 14.3 0.0 0.26 11.6 0.0 2.4 2 1 1 3 3 3 0 HEAT repeats DUF566 PF04484.7 EWM22461.1 - 7.5 5.9 9.5 12 5.2 6.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) GFO_IDH_MocA PF01408.17 EWM22462.1 - 2.1e-24 86.3 0.0 3.3e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EWM22462.1 - 1.4e-12 47.4 0.0 2.8e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Peripla_BP_1 PF00532.16 EWM22462.1 - 0.0027 16.9 0.0 0.0043 16.2 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family Semialdhyde_dh PF01118.19 EWM22462.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain TPR_12 PF13424.1 EWM22463.1 - 4.8e-11 42.4 27.0 4.7e-06 26.4 0.7 7.7 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 EWM22463.1 - 2e-09 36.9 25.3 0.00014 21.4 0.3 8.1 8 1 0 8 8 8 4 TPR repeat TPR_19 PF14559.1 EWM22463.1 - 2e-08 34.4 8.5 6.7 7.1 0.6 7.4 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.12 EWM22463.1 - 2.2e-08 33.3 28.3 0.46 10.5 0.2 9.3 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_14 PF13428.1 EWM22463.1 - 4.4e-08 33.0 12.4 0.023 15.2 0.0 7.6 7 2 2 9 9 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 EWM22463.1 - 1e-06 28.0 3.7 2.7 8.0 0.0 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.23 EWM22463.1 - 3.6e-05 23.1 30.7 0.24 11.0 0.3 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat Apc3 PF12895.2 EWM22463.1 - 4.2e-05 23.6 18.5 0.21 11.7 0.2 7.0 6 1 1 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EWM22463.1 - 0.0025 16.9 1.9 10 5.1 0.1 4.7 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EWM22463.1 - 0.0031 18.1 21.7 0.91 10.2 0.0 7.3 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 EWM22463.1 - 0.0057 16.4 2.0 11 5.9 0.0 4.3 4 1 0 4 4 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EWM22463.1 - 0.0063 16.2 8.8 22 5.1 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.9 EWM22463.1 - 0.041 14.3 12.9 2.8 8.6 0.1 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 EWM22463.1 - 0.046 13.6 17.5 5.6 7.0 0.0 6.5 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 EWM22463.1 - 0.11 12.7 15.5 5 7.5 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 EWM22463.1 - 0.3 11.6 11.4 18 6.0 0.1 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF1325 PF07039.6 EWM22464.1 - 1.9e-22 79.2 0.1 2.7e-22 78.7 0.1 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain SAP30_Sin3_bdg PF13867.1 EWM22464.1 - 8.8e-08 31.9 0.0 1.5e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF4537 PF15057.1 EWM22464.1 - 0.0073 16.0 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) TUDOR PF00567.19 EWM22464.1 - 0.1 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Tudor domain IBR PF01485.16 EWM22465.1 - 4.3e-17 61.7 28.3 2e-10 40.3 9.9 4.2 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 EWM22465.1 - 9.9e-07 28.4 6.5 9.9e-07 28.4 4.5 3.9 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 EWM22465.1 - 2.6e-06 27.3 6.9 2.6e-06 27.3 4.8 4.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EWM22465.1 - 3.6e-05 23.3 5.8 3.6e-05 23.3 4.1 3.7 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EWM22465.1 - 7.8e-05 22.2 0.4 7.8e-05 22.2 0.3 4.5 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EWM22465.1 - 0.021 14.7 4.9 0.021 14.7 3.4 4.5 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EWM22465.1 - 8.2 6.0 16.7 0.31 10.6 0.9 3.7 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 MFS_1 PF07690.11 EWM22466.1 - 1.1e-38 132.8 26.5 2e-30 105.6 5.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EWM22466.1 - 1.2e-06 26.9 7.1 4.6e-06 25.0 1.0 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector Sugar_tr PF00083.19 EWM22466.1 - 3.7e-05 22.4 15.2 0.00015 20.4 10.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter Nucleos_tra2_C PF07662.8 EWM22466.1 - 0.0089 15.5 0.8 0.022 14.2 0.5 1.8 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus RRM_1 PF00076.17 EWM22467.1 - 1.1e-46 156.2 0.0 2.2e-17 62.4 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM22467.1 - 3.1e-42 142.3 0.0 1.2e-13 50.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM22467.1 - 2.4e-16 59.3 0.0 0.00019 21.2 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EWM22467.1 - 2.8e-06 26.9 0.1 0.0097 15.6 0.0 2.7 1 1 1 2 2 2 2 Limkain b1 RRM_3 PF08777.6 EWM22467.1 - 0.0022 17.8 0.0 0.52 10.1 0.0 3.1 3 0 0 3 3 3 1 RNA binding motif Rtf2 PF04641.7 EWM22468.1 - 2.1e-52 177.9 0.4 5e-52 176.6 0.2 1.5 1 1 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 EWM22468.1 - 0.042 13.3 0.0 0.096 12.2 0.0 1.7 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PIGA PF08288.7 EWM22469.1 - 2.1e-41 140.1 1.2 9.7e-41 138.0 0.5 2.3 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EWM22469.1 - 1.3e-24 86.5 0.0 2.2e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EWM22469.1 - 2.6e-16 59.8 0.4 1.1e-15 57.8 0.3 2.1 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 EWM22469.1 - 2.4e-15 57.0 0.4 6.8e-15 55.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 EWM22469.1 - 7.4e-12 45.5 0.0 1.8e-11 44.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EWM22469.1 - 0.00011 22.3 0.2 0.00052 20.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 EWM22469.1 - 0.00081 19.2 0.2 0.0015 18.3 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_transf_5 PF08323.6 EWM22469.1 - 0.05 13.0 0.1 0.097 12.1 0.1 1.5 1 1 0 1 1 1 0 Starch synthase catalytic domain Ub-Mut7C PF14451.1 EWM22469.1 - 0.076 12.5 0.4 0.41 10.2 0.0 2.3 3 0 0 3 3 3 0 Mut7-C ubiquitin Glyco_transf_8 PF01501.15 EWM22470.1 - 0.087 12.1 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 8 DENN PF02141.16 EWM22471.1 - 6.6e-24 84.6 4.0 8.5e-21 74.5 0.9 2.4 2 0 0 2 2 2 2 DENN (AEX-3) domain uDENN PF03456.13 EWM22471.1 - 9e-06 25.5 0.0 2.6e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 uDENN domain Herpes_BLRF2 PF05812.7 EWM22471.1 - 0.02 14.6 0.2 0.02 14.6 0.1 1.8 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein DUF3007 PF11460.3 EWM22472.1 - 4.5e-25 87.7 0.8 4.5e-25 87.7 0.6 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3007) DUF1772 PF08592.6 EWM22472.1 - 0.39 10.4 3.6 0.27 10.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) Thioesterase PF00975.15 EWM22473.1 - 3.6e-19 69.9 0.0 7.6e-19 68.8 0.0 1.5 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.2 EWM22473.1 - 0.00013 21.9 0.0 0.00025 20.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 EWM22473.1 - 0.0045 16.3 0.0 0.0088 15.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.2 EWM22473.1 - 0.01 15.6 0.0 0.016 14.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 EWM22473.1 - 0.016 14.6 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) AAA PF00004.24 EWM22474.1 - 4.9e-43 146.4 0.0 2.9e-35 121.3 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EWM22474.1 - 6.7e-08 32.7 5.4 0.0013 18.7 0.2 4.3 2 2 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.9 EWM22474.1 - 2.1e-07 30.7 0.0 0.00068 19.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EWM22474.1 - 2.8e-06 27.5 0.5 0.045 13.8 0.0 3.6 2 2 0 2 2 2 2 AAA domain NACHT PF05729.7 EWM22474.1 - 2.2e-05 24.2 0.1 0.54 9.8 0.0 3.6 3 1 0 3 3 3 1 NACHT domain TIP49 PF06068.8 EWM22474.1 - 2.6e-05 23.1 0.0 0.00069 18.4 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus RNA_helicase PF00910.17 EWM22474.1 - 8.5e-05 22.6 0.0 0.0093 16.1 0.0 2.3 2 0 0 2 2 2 1 RNA helicase RuvB_N PF05496.7 EWM22474.1 - 0.0001 21.4 0.1 0.023 13.7 0.0 2.8 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EWM22474.1 - 0.00013 21.6 0.9 1.3 8.7 0.0 3.9 3 0 0 3 3 3 1 Part of AAA domain Mg_chelatase PF01078.16 EWM22474.1 - 0.00014 21.0 0.5 0.51 9.4 0.0 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 EWM22474.1 - 0.00023 21.1 0.0 0.52 10.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EWM22474.1 - 0.00044 20.1 0.1 0.061 13.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EWM22474.1 - 0.00075 20.3 0.0 0.014 16.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 EWM22474.1 - 0.0069 15.8 0.1 0.76 9.2 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EWM22474.1 - 0.01 15.8 0.1 3.6 7.6 0.0 2.8 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_18 PF13238.1 EWM22474.1 - 0.017 15.4 0.0 0.48 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EWM22474.1 - 0.021 14.2 1.0 1.2 8.4 0.3 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_28 PF13521.1 EWM22474.1 - 0.022 14.7 0.0 0.83 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EWM22474.1 - 0.029 14.2 0.0 0.3 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EWM22474.1 - 0.046 14.0 2.3 0.11 12.7 0.2 2.5 3 0 0 3 3 3 0 ABC transporter Rad17 PF03215.10 EWM22474.1 - 0.078 11.6 0.0 0.41 9.2 0.0 1.8 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein DnaB_C PF03796.10 EWM22474.1 - 0.17 10.7 0.0 0.45 9.3 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain DUF1499 PF07386.6 EWM22476.1 - 3.6e-10 40.0 0.0 5.2e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1499) TOM13 PF08219.6 EWM22476.1 - 0.12 12.1 0.1 0.27 11.0 0.1 1.6 1 0 0 1 1 1 0 Outer membrane protein TOM13 PgaD PF13994.1 EWM22476.1 - 0.16 11.4 1.4 3.6 7.0 0.0 2.3 2 0 0 2 2 2 0 PgaD-like protein DUF2763 PF10961.3 EWM22477.1 - 0.11 12.8 0.5 0.11 12.8 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) DUF2981 PF11200.3 EWM22477.1 - 0.46 9.4 2.5 0.57 9.2 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) CBFD_NFYB_HMF PF00808.18 EWM22478.1 - 0.0083 16.1 0.1 0.039 14.0 0.0 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DsbD PF02683.10 EWM22479.1 - 2.6e-35 121.9 9.0 4.4e-35 121.2 6.2 1.3 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DsbD_2 PF13386.1 EWM22479.1 - 4.3e-11 42.9 17.5 1.3e-10 41.3 10.6 2.0 2 1 1 3 3 3 2 Cytochrome C biogenesis protein transmembrane region Abhydrolase_6 PF12697.2 EWM22480.1 - 0.043 13.6 0.0 0.29 10.9 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF4477 PF14780.1 EWM22481.1 - 2.9e-07 30.0 3.0 5.6e-07 29.1 2.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) PsaN PF05479.6 EWM22481.1 - 0.024 14.5 4.3 0.031 14.2 0.3 2.9 3 0 0 3 3 3 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) DUF208 PF02677.9 EWM22481.1 - 0.029 14.1 0.3 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized BCR, COG1636 Pro_isomerase PF00160.16 EWM22482.1 - 1.4e-47 161.7 0.0 2.6e-47 160.8 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 EWM22482.1 - 1.6e-12 47.2 0.3 1.6e-12 47.2 0.2 1.9 2 0 0 2 2 2 1 Rtf2 RING-finger UDG PF03167.14 EWM22483.1 - 1.3e-34 118.8 0.0 2.3e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Aldo_ket_red PF00248.16 EWM22484.1 - 5e-49 166.6 0.0 5.8e-49 166.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1153 PF06627.6 EWM22484.1 - 0.13 12.1 0.0 4.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1153) Scaffolding_pro PF11418.3 EWM22485.1 - 0.0051 17.1 1.1 0.0051 17.1 0.8 2.4 2 0 0 2 2 2 1 Phi29 scaffolding protein DUF3450 PF11932.3 EWM22485.1 - 0.03 13.5 27.0 0.1 11.8 5.9 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) PX PF00787.19 EWM22485.1 - 0.056 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 PX domain Baculo_gp64 PF03273.8 EWM22485.1 - 0.34 9.0 0.4 0.57 8.2 0.3 1.3 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family Spc7 PF08317.6 EWM22485.1 - 5.9 5.4 23.3 0.017 13.8 6.7 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein Med9 PF07544.8 EWM22485.1 - 7 6.4 13.6 0.093 12.4 2.3 3.2 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 zf-RING_2 PF13639.1 EWM22486.1 - 8.6e-14 51.0 6.9 1.8e-13 50.0 4.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EWM22486.1 - 1.3e-07 31.6 7.4 3.3e-07 30.3 5.1 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EWM22486.1 - 7.5e-06 25.5 4.6 1.7e-05 24.4 3.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EWM22486.1 - 9.5e-06 25.2 3.1 1.9e-05 24.3 2.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EWM22486.1 - 2.1e-05 24.4 5.2 4.2e-05 23.4 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EWM22486.1 - 0.00017 21.2 6.5 0.00037 20.0 4.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EWM22486.1 - 0.0005 19.8 1.7 0.0011 18.7 1.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.6 EWM22486.1 - 0.13 12.2 3.0 0.21 11.6 2.1 1.3 1 0 0 1 1 1 0 RING-like domain zf-P11 PF03854.9 EWM22486.1 - 0.13 11.7 2.2 0.36 10.3 1.5 1.7 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_UBOX PF13445.1 EWM22486.1 - 0.14 11.9 6.7 0.067 12.9 2.8 1.9 2 0 0 2 2 2 0 RING-type zinc-finger RINGv PF12906.2 EWM22486.1 - 0.86 9.7 5.4 2 8.5 3.7 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.1 EWM22486.1 - 0.88 9.4 5.0 1.7 8.5 3.5 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EWM22486.1 - 1.8 8.2 4.7 2.1 7.9 2.6 1.6 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Methyltransf_16 PF10294.4 EWM22487.1 - 3.4e-18 65.6 0.2 1.1e-16 60.8 0.1 2.1 1 1 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EWM22487.1 - 6.3e-05 22.4 0.0 0.0001 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EWM22487.1 - 6.6e-05 23.4 0.1 0.00013 22.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.11 EWM22487.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein ATP-synt_D PF01813.12 EWM22488.1 - 3.8e-61 206.0 2.2 3.8e-61 206.0 1.5 1.6 1 1 1 2 2 2 1 ATP synthase subunit D TORC_N PF12884.2 EWM22488.1 - 0.089 13.3 0.4 3 8.4 0.0 2.4 2 0 0 2 2 2 0 Transducer of regulated CREB activity, N terminus Ubiq_cyt_C_chap PF03981.7 EWM22488.1 - 0.67 9.7 3.3 4.3 7.1 0.3 2.5 1 1 1 2 2 2 0 Ubiquinol-cytochrome C chaperone FlgN PF05130.7 EWM22488.1 - 1.2 9.3 5.2 3.2 7.9 2.2 2.3 2 1 0 2 2 2 0 FlgN protein TrmE_N PF10396.4 EWM22489.1 - 9.8e-26 89.9 0.0 5.5e-25 87.5 0.0 2.1 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 EWM22489.1 - 1.5e-21 76.5 0.9 2.4e-20 72.7 0.1 2.8 2 0 0 2 2 2 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 EWM22489.1 - 2.9e-19 69.1 0.0 8.8e-19 67.5 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EWM22489.1 - 7.7e-06 25.2 0.0 1.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_17 PF13207.1 EWM22489.1 - 1.7e-05 25.5 0.0 0.00022 22.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 EWM22489.1 - 2.1e-05 24.3 0.0 3.5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.1 EWM22489.1 - 0.0017 18.3 0.0 0.0042 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EWM22489.1 - 0.002 18.4 0.0 0.0039 17.4 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 EWM22489.1 - 0.0021 18.2 0.0 0.0067 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 EWM22489.1 - 0.0049 17.3 0.0 0.01 16.3 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_24 PF13479.1 EWM22489.1 - 0.0054 16.3 0.0 0.13 11.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EWM22489.1 - 0.017 14.6 0.0 0.11 11.8 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_25 PF13481.1 EWM22489.1 - 0.018 14.4 2.2 0.052 12.9 0.8 2.5 2 1 0 2 2 2 0 AAA domain Arf PF00025.16 EWM22489.1 - 0.022 14.0 0.0 0.044 13.0 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family MobB PF03205.9 EWM22489.1 - 0.034 13.8 0.0 0.23 11.1 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EWM22489.1 - 0.047 13.6 1.5 0.11 12.4 0.3 2.1 1 1 1 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 EWM22489.1 - 0.058 12.5 0.0 0.14 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 EWM22489.1 - 0.065 13.5 0.0 0.27 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.11 EWM22489.1 - 0.16 11.0 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 AIG1 family AAA_14 PF13173.1 EWM22489.1 - 0.18 11.6 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIM PF00121.13 EWM22490.1 - 1.9e-12 46.7 0.0 2.4e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase Ank_3 PF13606.1 EWM22492.1 - 0.072 13.3 0.0 1.2 9.5 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeat Acetyltransf_1 PF00583.19 EWM22493.1 - 1.3e-11 44.3 0.1 2e-11 43.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EWM22493.1 - 2.9e-06 26.9 0.0 4.7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EWM22493.1 - 0.00019 21.5 0.0 0.00028 20.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EWM22493.1 - 0.00025 21.1 0.3 0.001 19.1 0.1 2.0 1 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EWM22493.1 - 0.00037 20.3 0.1 0.0008 19.2 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EWM22493.1 - 0.0055 16.6 0.0 0.0074 16.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PRP21_like_P PF12230.3 EWM22494.1 - 1.1e-35 123.2 1.5 1.7e-35 122.5 0.2 2.0 2 1 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EWM22494.1 - 3.1e-35 119.6 0.4 1.1e-17 63.3 0.1 2.3 2 0 0 2 2 2 2 Surp module INTS5_N PF14837.1 EWM22494.1 - 0.11 11.8 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 Integrator complex subunit 5 N-terminus PAN_4 PF14295.1 EWM22495.1 - 0.0043 16.7 1.2 0.011 15.3 0.8 1.7 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 EWM22495.1 - 0.066 12.9 0.3 0.14 11.9 0.2 1.5 1 0 0 1 1 1 0 PAN domain tRNA-synt_1b PF00579.20 EWM22497.1 - 4.6e-73 245.8 0.0 5.8e-73 245.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.20 EWM22497.1 - 9.9e-05 21.7 0.0 0.00026 20.3 0.0 1.7 1 0 0 1 1 1 1 S4 domain Med21 PF11221.3 EWM22498.1 - 0.013 15.4 0.7 1.6 8.6 0.6 2.2 1 1 0 2 2 2 0 Subunit 21 of Mediator complex DUF777 PF05606.6 EWM22498.1 - 0.043 13.0 0.1 0.064 12.4 0.1 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF777) HALZ PF02183.13 EWM22498.1 - 0.13 12.0 0.3 0.19 11.4 0.2 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper Bestrophin PF01062.16 EWM22501.1 - 7.1e-26 90.8 0.1 9.7e-26 90.3 0.0 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Glycos_transf_1 PF00534.15 EWM22501.1 - 0.00064 19.1 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 TMF_DNA_bd PF12329.3 EWM22503.1 - 2e-05 24.2 12.8 2e-05 24.2 8.9 5.4 5 2 2 7 7 7 1 TATA element modulatory factor 1 DNA binding Tropomyosin_1 PF12718.2 EWM22503.1 - 0.017 15.0 47.3 0.083 12.7 7.7 3.6 1 1 2 3 3 3 0 Tropomyosin like SecIII_SopE_N PF05364.9 EWM22503.1 - 0.036 13.9 2.4 0.074 12.8 1.4 1.7 1 1 0 1 1 1 0 Salmonella type III secretion SopE effector N-terminus DUF4515 PF14988.1 EWM22503.1 - 5.6 6.5 46.4 0.7 9.5 19.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4515) Pkinase PF00069.20 EWM22504.1 - 8.6e-53 179.1 0.0 1.2e-52 178.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM22504.1 - 8e-25 87.3 0.0 1.2e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase IF2_assoc PF08364.6 EWM22504.1 - 0.063 13.3 1.2 0.34 10.9 0.2 2.4 2 0 0 2 2 2 0 Bacterial translation initiation factor IF-2 associated region Kinase-like PF14531.1 EWM22504.1 - 0.079 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like HA2 PF04408.18 EWM22506.1 - 2.6e-25 88.4 0.5 5.5e-25 87.3 0.0 1.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EWM22506.1 - 3.3e-18 65.5 0.0 2.1e-17 62.9 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EWM22506.1 - 5.9e-13 48.4 0.0 1.4e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EWM22506.1 - 9.9e-06 25.1 0.1 0.00018 21.0 0.1 2.7 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EWM22506.1 - 0.011 15.8 0.1 0.072 13.2 0.0 2.4 2 1 0 2 2 2 0 AAA domain T2SE PF00437.15 EWM22506.1 - 0.031 13.2 0.0 0.062 12.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein HA2 PF04408.18 EWM22507.1 - 1.7e-25 89.0 0.0 3.4e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EWM22507.1 - 1.9e-18 66.3 0.1 1.2e-17 63.7 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EWM22507.1 - 3.9e-13 49.0 0.0 8.6e-13 47.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4259 PF14078.1 EWM22507.1 - 0.11 13.0 0.1 0.21 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) Pkinase PF00069.20 EWM22508.1 - 3e-35 121.6 0.0 1.4e-34 119.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM22508.1 - 1.5e-19 70.0 0.0 2.2e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase NUDIX PF00293.23 EWM22509.1 - 2.2e-14 53.2 0.3 3.8e-14 52.4 0.2 1.4 1 0 0 1 1 1 1 NUDIX domain TIM PF00121.13 EWM22510.1 - 1.2e-25 90.0 0.3 1.3e-25 89.8 0.2 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase PSD5 PF07637.6 EWM22511.1 - 3.7 7.6 5.3 6.4 6.8 0.1 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1595) PCI PF01399.22 EWM22513.1 - 2e-16 60.1 0.0 2.6e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 PCI domain mTERF PF02536.9 EWM22514.1 - 0.00045 18.9 0.0 0.0019 16.8 0.0 1.8 2 1 0 2 2 2 1 mTERF mTERF PF02536.9 EWM22515.1 - 0.00061 18.4 0.0 0.0024 16.5 0.0 1.8 2 0 0 2 2 2 1 mTERF Sod_Fe_C PF02777.13 EWM22517.1 - 1.3e-42 143.9 1.3 9.3e-42 141.1 0.2 2.2 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EWM22517.1 - 5.3e-29 100.3 0.3 5.3e-29 100.3 0.2 1.5 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Hydrolase_4 PF12146.3 EWM22518.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase TPR_11 PF13414.1 EWM22520.1 - 1.7e-21 75.6 13.9 3.6e-13 48.9 0.3 2.6 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.12 EWM22520.1 - 1.2e-19 68.5 8.1 1.1e-06 28.0 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EWM22520.1 - 1.3e-17 62.6 10.7 1.7e-05 25.0 0.7 4.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 EWM22520.1 - 3e-17 61.3 0.2 1.7e-07 30.5 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EWM22520.1 - 5.9e-16 58.6 18.6 5.3e-07 30.1 6.9 3.2 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EWM22520.1 - 4.7e-13 48.8 9.9 8e-08 32.1 0.4 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EWM22520.1 - 8e-13 47.1 0.3 5.5e-05 22.6 0.0 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 EWM22520.1 - 1e-12 46.8 5.1 0.0066 16.1 0.0 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 EWM22520.1 - 1.7e-12 46.4 1.0 0.0018 18.3 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 EWM22520.1 - 2.1e-12 47.1 6.1 7.6e-06 26.1 0.7 3.2 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.1 EWM22520.1 - 4.5e-08 33.0 5.9 0.05 14.0 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 EWM22520.1 - 2e-07 30.7 5.9 7.8e-05 22.4 0.4 2.7 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 EWM22520.1 - 3.1e-05 23.7 14.2 0.1 12.5 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 EWM22520.1 - 9.8e-05 22.4 1.0 0.072 13.2 0.1 2.3 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 EWM22520.1 - 0.0025 18.0 0.3 0.21 12.0 0.0 4.1 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_20 PF14561.1 EWM22520.1 - 0.0053 16.8 2.3 0.49 10.5 0.7 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat Glyco_hyd_65N_2 PF14498.1 EWM22520.1 - 0.092 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain 4HB_MCP_1 PF12729.2 EWM22520.1 - 0.39 10.0 0.0 0.39 10.0 0.0 2.1 3 0 0 3 3 3 0 Four helix bundle sensory module for signal transduction GatB_N PF02934.10 EWM22521.1 - 1.1e-83 280.4 0.0 1.4e-83 280.0 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 EWM22521.1 - 8.4e-23 80.7 0.0 3.7e-22 78.6 0.0 2.1 2 1 0 2 2 2 1 GatB domain AAA_12 PF13087.1 EWM22523.1 - 1.6e-56 190.8 0.0 2.1e-56 190.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EWM22523.1 - 1.5e-29 103.2 0.0 2.7e-29 102.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EWM22523.1 - 0.0063 16.0 0.0 0.72 9.3 0.0 2.2 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EWM22523.1 - 0.048 13.2 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain PEP-utilisers_N PF05524.8 EWM22525.1 - 0.056 13.2 0.7 0.087 12.6 0.5 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal BAAT_C PF08840.6 EWM22525.1 - 0.088 12.4 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal PEP-utilisers_N PF05524.8 EWM22526.1 - 0.056 13.2 0.7 0.087 12.6 0.5 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal BAAT_C PF08840.6 EWM22526.1 - 0.088 12.4 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Nop14 PF04147.7 EWM22527.1 - 4.5e-05 21.6 21.4 5.7e-05 21.2 14.9 1.1 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 EWM22527.1 - 0.0015 16.6 29.7 0.002 16.2 20.6 1.0 1 0 0 1 1 1 1 CDC45-like protein CENP-T PF15511.1 EWM22527.1 - 0.0018 17.5 14.3 0.0023 17.2 9.9 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Nop53 PF07767.6 EWM22527.1 - 0.03 13.3 30.3 0.048 12.6 21.0 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF1510 PF07423.6 EWM22527.1 - 0.052 12.9 14.2 0.076 12.3 9.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TFIIA PF03153.8 EWM22527.1 - 0.17 11.7 17.0 0.23 11.3 11.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RNA_pol_3_Rpc31 PF11705.3 EWM22527.1 - 0.45 10.4 27.1 0.71 9.7 18.8 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Cwf_Cwc_15 PF04889.7 EWM22527.1 - 0.65 9.6 25.6 0.89 9.2 17.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2722 PF10846.3 EWM22527.1 - 0.88 8.5 6.0 1.1 8.2 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF2890 PF11081.3 EWM22527.1 - 2.1 8.3 25.9 1.9 8.5 17.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Paf1 PF03985.8 EWM22527.1 - 5.3 5.6 23.3 7.3 5.2 16.2 1.1 1 0 0 1 1 1 0 Paf1 Merozoite_SPAM PF07133.6 EWM22527.1 - 5.5 6.8 31.6 8.4 6.2 21.9 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CobT PF06213.7 EWM22527.1 - 6.1 5.8 28.4 9 5.3 19.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT N6-adenineMlase PF10237.4 EWM22528.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase HALZ PF02183.13 EWM22529.1 - 0.1 12.3 0.4 2.4 7.9 0.0 2.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF563 PF04577.9 EWM22530.1 - 3.9e-22 79.1 0.0 5e-17 62.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF563) PAP2_C PF14360.1 EWM22532.1 - 8.7e-12 45.1 8.0 8.7e-12 45.1 5.6 2.2 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2_3 PF14378.1 EWM22532.1 - 2.9e-06 26.9 4.2 2.9e-06 26.9 2.9 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.16 EWM22532.1 - 0.0057 16.3 2.5 0.0057 16.3 1.7 2.5 2 1 0 2 2 2 1 PAP2 superfamily DUF4013 PF13197.1 EWM22532.1 - 0.98 8.7 10.8 0.024 13.9 1.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4013) Metallophos PF00149.23 EWM22533.1 - 4.1e-25 88.3 0.1 5.3e-25 87.9 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Thioredoxin_8 PF13905.1 EWM22534.1 - 6.9e-13 48.5 0.0 1.1e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EWM22534.1 - 2.6e-07 30.3 0.0 5.7e-07 29.2 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 EWM22534.1 - 0.00015 21.3 0.0 0.00024 20.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin DTHCT PF08070.6 EWM22537.1 - 0.18 12.5 2.1 0.21 12.2 1.4 1.1 1 0 0 1 1 1 0 DTHCT (NUC029) region BSD PF03909.12 EWM22539.1 - 2.4e-12 46.3 0.8 3.1e-07 30.0 0.3 2.2 2 0 0 2 2 2 2 BSD domain SHOCT PF09851.4 EWM22539.1 - 0.041 13.3 0.2 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 Short C-terminal domain UFD1 PF03152.9 EWM22540.1 - 5.8e-05 22.3 0.1 8e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Peptidase_M32 PF02074.10 EWM22541.1 - 9.4e-131 436.8 0.0 1.2e-130 436.4 0.0 1.1 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase UFD1 PF03152.9 EWM22542.1 - 4.8e-33 113.7 0.0 5.7e-33 113.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Utp11 PF03998.8 EWM22544.1 - 5.6e-50 170.4 7.2 6.9e-50 170.1 5.0 1.0 1 0 0 1 1 1 1 Utp11 protein Metallophos_3 PF14582.1 EWM22545.1 - 0.0075 15.4 0.0 0.017 14.3 0.0 1.5 1 0 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily TPR_2 PF07719.12 EWM22548.1 - 6.8e-07 28.7 0.0 0.15 12.0 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EWM22548.1 - 2.3e-06 28.1 0.1 3.2 8.5 0.0 3.5 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EWM22548.1 - 5e-05 23.1 0.1 2.4 8.1 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EWM22548.1 - 0.0025 18.1 0.0 21 5.8 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EWM22548.1 - 0.0051 16.4 0.0 3.3 7.4 0.0 3.2 3 0 0 3 3 3 1 TPR repeat TPR_14 PF13428.1 EWM22548.1 - 0.0068 16.9 1.6 10 7.0 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat HemY_N PF07219.8 EWM22548.1 - 0.013 15.0 0.3 0.037 13.5 0.1 1.8 2 0 0 2 2 2 0 HemY protein N-terminus HrpB1_HrpK PF09613.5 EWM22548.1 - 0.029 13.8 0.1 1.9 7.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_7 PF13176.1 EWM22548.1 - 0.038 13.7 0.0 29 4.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 EWM22548.1 - 0.04 14.3 1.0 71 4.2 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 EWM22548.1 - 0.051 13.4 0.1 1.1 9.1 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EWM22548.1 - 0.13 11.9 0.0 35 4.2 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.27 EWM22550.1 - 1.6e-37 126.0 4.6 6.2e-10 38.5 0.1 8.5 10 0 0 10 10 10 5 WD domain, G-beta repeat eIF2A PF08662.6 EWM22550.1 - 0.00038 20.2 0.0 0.28 10.8 0.0 4.0 3 2 2 5 5 5 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EWM22550.1 - 0.005 16.4 0.1 13 5.5 0.0 4.1 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 EWM22550.1 - 0.02 14.1 0.3 21 4.5 0.0 3.8 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Kelch_6 PF13964.1 EWM22550.1 - 0.027 14.6 0.4 44 4.4 0.0 4.0 3 0 0 3 3 3 0 Kelch motif DUF1513 PF07433.6 EWM22550.1 - 0.1 11.4 0.1 1.2 8.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) Utp12 PF04003.7 EWM22553.1 - 3.8e-10 39.6 0.6 5.9e-10 39.0 0.4 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.27 EWM22553.1 - 0.0006 19.5 0.1 4.4 7.3 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat Pkinase PF00069.20 EWM22555.1 - 6.3e-69 232.0 0.0 7.4e-69 231.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM22555.1 - 1e-39 136.2 0.0 1.2e-39 135.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EWM22555.1 - 2.1e-13 49.8 0.0 1.4e-10 40.6 0.0 2.1 1 1 0 2 2 2 2 Kinase-like APH PF01636.18 EWM22555.1 - 0.0041 16.8 1.6 0.0093 15.7 1.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Abp2 PF09441.5 EWM22555.1 - 0.049 13.5 0.0 0.071 13.0 0.0 1.2 1 0 0 1 1 1 0 ARS binding protein 2 DUF599 PF04654.7 EWM22556.1 - 4.1e-15 55.5 2.2 5.9e-15 55.0 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF599 Trypsin PF00089.21 EWM22557.1 - 9.6e-06 25.3 0.0 1.6e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 EWM22557.1 - 1.1e-05 25.4 0.0 2.2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain Sigma70_ner PF04546.8 EWM22558.1 - 0.00017 21.2 5.7 0.00024 20.8 4.0 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region Paf1 PF03985.8 EWM22558.1 - 0.00025 19.9 14.7 0.00034 19.4 10.2 1.1 1 0 0 1 1 1 1 Paf1 Adeno_terminal PF02459.10 EWM22558.1 - 0.0024 16.1 5.3 0.0031 15.7 3.7 1.1 1 0 0 1 1 1 1 Adenoviral DNA terminal protein Cytomega_UL84 PF06284.6 EWM22558.1 - 0.0026 16.2 0.8 0.0032 15.9 0.5 1.1 1 0 0 1 1 1 1 Cytomegalovirus UL84 protein CobT PF06213.7 EWM22558.1 - 0.0044 16.1 9.1 0.006 15.7 6.3 1.2 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT BUD22 PF09073.5 EWM22558.1 - 0.0057 15.7 4.7 0.0071 15.4 3.3 1.2 1 0 0 1 1 1 1 BUD22 RXT2_N PF08595.6 EWM22558.1 - 0.0068 16.2 3.4 0.011 15.5 2.4 1.4 1 0 0 1 1 1 1 RXT2-like, N-terminal Ycf1 PF05758.7 EWM22558.1 - 0.009 13.7 1.1 0.01 13.6 0.8 1.1 1 0 0 1 1 1 1 Ycf1 RRN3 PF05327.6 EWM22558.1 - 0.014 13.5 2.6 0.019 13.1 1.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 UBN_AB PF14075.1 EWM22558.1 - 0.025 14.2 5.7 0.035 13.7 4.0 1.1 1 0 0 1 1 1 0 Ubinuclein conserved middle domain Radial_spoke PF04712.7 EWM22558.1 - 0.032 12.9 15.2 0.046 12.4 10.5 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein VID27 PF08553.5 EWM22558.1 - 0.042 12.0 9.7 0.054 11.7 6.7 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein CENP-B_dimeris PF09026.5 EWM22558.1 - 0.043 14.0 16.0 0.11 12.7 11.1 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.1 EWM22558.1 - 0.043 13.4 3.7 0.077 12.6 2.6 1.4 1 0 0 1 1 1 0 FAM176 family TRAP_alpha PF03896.11 EWM22558.1 - 0.045 12.7 7.7 0.065 12.2 5.4 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Tim54 PF11711.3 EWM22558.1 - 0.047 12.2 1.7 0.062 11.8 1.2 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Hus1 PF04005.7 EWM22558.1 - 0.05 12.5 0.1 0.082 11.8 0.1 1.3 1 0 0 1 1 1 0 Hus1-like protein DDHD PF02862.12 EWM22558.1 - 0.13 11.9 1.0 0.21 11.3 0.7 1.3 1 0 0 1 1 1 0 DDHD domain Spore_coat_CotO PF14153.1 EWM22558.1 - 0.16 11.4 9.5 0.25 10.7 6.6 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF3306 PF11748.3 EWM22558.1 - 0.21 12.2 6.9 0.47 11.1 4.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) DUF2360 PF10152.4 EWM22558.1 - 0.24 11.6 0.1 0.24 11.6 0.0 2.5 3 0 0 3 3 2 0 Predicted coiled-coil domain-containing protein (DUF2360) HABP4_PAI-RBP1 PF04774.10 EWM22558.1 - 0.38 11.2 17.4 0.63 10.5 12.1 1.3 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family Fmp27 PF10344.4 EWM22558.1 - 0.6 7.7 2.9 0.8 7.3 2.0 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 CDC45 PF02724.9 EWM22558.1 - 0.67 7.9 10.1 0.92 7.4 7.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Rhabdo_ncap PF00945.13 EWM22558.1 - 1 7.8 3.2 1.4 7.4 2.2 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Drc1-Sld2 PF11719.3 EWM22558.1 - 1.4 7.9 8.8 2.7 7.0 6.1 1.4 1 0 0 1 1 1 0 DNA replication and checkpoint protein DUF4337 PF14235.1 EWM22558.1 - 1.8 8.3 4.7 2.6 7.8 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) RNA_pol_3_Rpc31 PF11705.3 EWM22558.1 - 1.9 8.3 21.1 3.6 7.4 14.6 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RNase_H2-Ydr279 PF09468.5 EWM22558.1 - 1.9 7.6 5.2 3.1 6.9 3.6 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF1682 PF07946.9 EWM22558.1 - 1.9 7.2 9.7 2.7 6.7 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF4199 PF13858.1 EWM22558.1 - 2.3 8.1 3.3 3.7 7.4 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) OAD_gamma PF04277.8 EWM22558.1 - 2.4 8.5 3.7 4.9 7.6 2.6 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF1510 PF07423.6 EWM22558.1 - 3.8 6.8 14.5 5.7 6.2 10.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Nop14 PF04147.7 EWM22558.1 - 3.9 5.2 20.3 5.8 4.6 14.0 1.1 1 0 0 1 1 1 0 Nop14-like family Pox_RNA_Pol_19 PF05320.7 EWM22558.1 - 4.1 7.1 12.5 1 9.1 6.6 1.5 2 0 0 2 2 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DNA_pol_phi PF04931.8 EWM22558.1 - 4.4 4.9 23.1 5.9 4.5 16.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi BTV_NS2 PF04514.7 EWM22558.1 - 8 5.2 9.3 12 4.6 6.5 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 YqfQ PF14181.1 EWM22558.1 - 9.5 6.2 11.0 18 5.3 7.6 1.4 1 0 0 1 1 1 0 YqfQ-like protein Lipase_3 PF01764.20 EWM22561.1 - 3.1e-24 85.2 0.0 5.2e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) C2 PF00168.25 EWM22561.1 - 0.0013 18.4 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 C2 domain Abhydrolase_6 PF12697.2 EWM22561.1 - 0.0038 17.1 0.0 0.0091 15.9 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 EWM22561.1 - 0.012 15.0 0.0 5.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.8 EWM22561.1 - 0.02 14.4 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EWM22561.1 - 0.049 13.3 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.20 EWM22562.1 - 7.2e-15 54.8 0.0 1.2e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) C2 PF00168.25 EWM22562.1 - 0.0012 18.6 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 C2 domain Abhydrolase_6 PF12697.2 EWM22562.1 - 0.004 17.0 0.1 0.0096 15.8 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 EWM22562.1 - 0.011 15.0 0.0 5.1 6.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.8 EWM22562.1 - 0.028 13.9 0.1 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EWM22562.1 - 0.069 12.9 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.11 EWM22563.1 - 1.1e-38 132.8 24.6 1.1e-38 132.8 17.1 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EWM22563.1 - 4.2e-08 32.1 1.7 4.2e-08 32.1 1.2 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter DUF106 PF01956.11 EWM22564.1 - 0.15 11.5 2.2 0.21 11.0 1.5 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 ROK PF00480.15 EWM22566.1 - 1.6e-13 50.9 0.0 1.8e-13 50.6 0.0 1.0 1 0 0 1 1 1 1 ROK family Bestrophin PF01062.16 EWM22571.1 - 0.00025 20.0 0.0 0.00036 19.5 0.0 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel UVR PF02151.14 EWM22575.1 - 0.011 15.2 1.4 0.024 14.1 1.0 1.6 1 0 0 1 1 1 0 UvrB/uvrC motif Vpu PF00558.14 EWM22575.1 - 0.3 10.6 0.1 0.3 10.6 0.1 2.7 4 0 0 4 4 4 0 Vpu protein EF-hand_6 PF13405.1 EWM22577.1 - 0.0036 17.0 0.2 0.0096 15.7 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 EWM22577.1 - 0.016 14.4 0.6 0.041 13.1 0.0 1.9 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.1 EWM22577.1 - 0.041 13.4 0.2 0.067 12.8 0.1 1.3 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_7 PF13499.1 EWM22577.1 - 0.058 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.1 EWM22577.1 - 0.071 12.4 1.5 0.29 10.5 0.1 2.3 2 0 0 2 2 2 0 EF hand DUF572 PF04502.8 EWM22578.1 - 1.4e-69 234.8 10.1 1.6e-69 234.6 7.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF866 PF05907.8 EWM22578.1 - 2.2e-05 23.9 1.4 2.9e-05 23.6 0.9 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) DUF2989 PF11207.3 EWM22578.1 - 0.029 13.8 0.3 0.06 12.7 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2989) Benyvirus_14KDa PF07255.6 EWM22578.1 - 0.056 13.3 0.7 0.26 11.1 0.5 1.9 1 1 1 2 2 2 0 Benyvirus 14KDa protein HMG_box PF00505.14 EWM22578.1 - 1.1 9.5 5.1 2 8.7 3.6 1.4 1 0 0 1 1 1 0 HMG (high mobility group) box Aldolase_II PF00596.16 EWM22579.1 - 2.3e-39 134.8 0.0 4.4e-39 133.9 0.0 1.5 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain HAD_2 PF13419.1 EWM22579.1 - 0.00035 20.8 0.0 0.0034 17.6 0.0 2.4 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase ARD PF03079.9 EWM22579.1 - 0.0007 19.5 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 ARD/ARD' family Ribosomal_S28e PF01200.13 EWM22580.1 - 2e-06 27.4 1.0 3.2e-06 26.7 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S28e Trp_syntA PF00290.15 EWM22581.1 - 2.6e-83 278.5 0.0 3.5e-83 278.0 0.0 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 EWM22581.1 - 2.6e-42 145.1 1.9 4.4e-42 144.3 1.3 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Kinocilin PF15033.1 EWM22581.1 - 0.013 15.0 0.6 0.029 13.8 0.4 1.6 1 0 0 1 1 1 0 Kinocilin protein His_biosynth PF00977.16 EWM22581.1 - 0.04 13.1 0.0 0.083 12.1 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein Ion_trans_2 PF07885.11 EWM22582.1 - 1.4e-07 31.1 9.0 3.2e-07 29.9 6.3 1.6 1 0 0 1 1 1 1 Ion channel TspO_MBR PF03073.10 EWM22582.1 - 0.017 14.6 1.7 0.034 13.6 1.2 1.5 1 0 0 1 1 1 0 TspO/MBR family Alph_Pro_TM PF09608.5 EWM22583.1 - 0.083 12.3 0.6 0.11 11.9 0.1 1.4 2 0 0 2 2 2 0 Putative transmembrane protein (Alph_Pro_TM) TFIID-18kDa PF02269.11 EWM22584.1 - 7e-26 89.8 0.7 8.6e-26 89.5 0.5 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 EWM22584.1 - 0.013 15.2 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.8 EWM22584.1 - 0.095 12.9 0.1 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 EWM22584.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PI3_PI4_kinase PF00454.22 EWM22588.1 - 2.6e-10 40.1 0.0 3.7e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase GIDA PF01134.17 EWM22590.1 - 3.7e-141 470.5 0.0 4.7e-141 470.2 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EWM22590.1 - 1.2e-14 54.1 0.0 3.2e-14 52.7 0.0 1.8 1 0 0 1 1 1 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 EWM22590.1 - 4.7e-08 33.1 0.5 1.1e-07 31.8 0.4 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EWM22590.1 - 3.5e-07 29.6 4.1 5.9e-07 28.9 2.8 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EWM22590.1 - 2.7e-05 23.1 2.5 2.7e-05 23.1 1.7 1.9 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EWM22590.1 - 4.2e-05 22.6 4.9 0.019 13.8 0.2 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EWM22590.1 - 0.0027 18.0 0.4 0.0089 16.4 0.3 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EWM22590.1 - 0.0032 16.6 2.1 0.017 14.2 1.4 2.1 1 1 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EWM22590.1 - 0.0063 15.0 3.6 0.045 12.2 0.4 2.6 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.1 EWM22590.1 - 0.017 15.1 0.6 0.19 11.8 0.7 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EWM22590.1 - 0.032 13.1 1.1 0.14 11.0 0.2 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Bactofilin PF04519.8 EWM22591.1 - 0.0011 18.9 12.6 0.12 12.4 2.5 4.5 3 1 1 4 4 4 2 Polymer-forming cytoskeletal DUF4098 PF13345.1 EWM22592.1 - 0.052 13.5 10.9 0.21 11.5 0.6 3.6 2 1 0 3 3 3 0 Domain of unknown function (DUF4098) DUF3540 PF12059.3 EWM22592.1 - 0.099 12.2 0.2 0.3 10.6 0.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3540) GST_N_2 PF13409.1 EWM22594.1 - 1.2e-17 63.6 0.0 3.3e-17 62.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EWM22594.1 - 3.8e-13 49.1 0.1 1.1e-12 47.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EWM22594.1 - 9.7e-06 25.7 0.0 0.075 13.2 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EWM22594.1 - 4.8e-05 23.7 0.0 9.5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EWM22594.1 - 5.6e-05 23.0 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Acetyltransf_1 PF00583.19 EWM22595.1 - 6.4e-15 54.9 0.0 1.6e-14 53.6 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EWM22595.1 - 1.7e-09 37.7 0.0 1.3e-08 34.8 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EWM22595.1 - 6.3e-07 29.0 0.0 1.5e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EWM22595.1 - 6.2e-06 26.1 0.1 1e-05 25.4 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EWM22595.1 - 2.1e-05 24.6 0.0 0.00015 21.8 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EWM22595.1 - 7.4e-05 22.7 0.0 0.00015 21.7 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EWM22595.1 - 0.0036 17.1 0.3 0.016 15.0 0.2 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EWM22595.1 - 0.016 15.1 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF3749 PF12568.3 EWM22595.1 - 0.029 13.9 0.0 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EWM22595.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-RING_2 PF13639.1 EWM22596.1 - 9.1e-10 38.2 7.8 1.6e-09 37.4 5.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EWM22596.1 - 1.7e-05 24.6 8.2 2.8e-05 24.0 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EWM22596.1 - 7.7e-05 22.2 5.3 0.00013 21.5 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EWM22596.1 - 0.00024 20.7 6.1 0.00044 19.9 4.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EWM22596.1 - 0.00079 19.0 7.5 0.0013 18.3 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EWM22596.1 - 0.029 14.4 6.6 0.057 13.5 4.5 1.5 1 1 0 1 1 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 EWM22596.1 - 0.039 13.7 4.7 0.07 12.9 3.2 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Dynactin_p62 PF05502.8 EWM22596.1 - 0.11 11.2 1.8 0.17 10.6 1.2 1.2 1 0 0 1 1 1 0 Dynactin p62 family zf-RING_4 PF14570.1 EWM22596.1 - 0.16 11.5 3.7 0.33 10.5 2.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 EWM22596.1 - 0.25 10.8 4.4 0.51 9.9 3.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 EWM22596.1 - 0.7 9.9 9.2 12 5.9 6.4 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 EWM22596.1 - 5.9 6.8 6.3 12 5.8 3.7 2.1 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Aa_trans PF01490.13 EWM22597.1 - 3.5e-44 150.9 21.3 4.4e-44 150.6 14.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EWM22597.1 - 1e-05 24.5 8.8 1e-05 24.5 6.1 2.3 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family MMTV_SAg PF01054.12 EWM22599.1 - 0.11 11.3 0.1 0.14 10.9 0.1 1.1 1 0 0 1 1 1 0 Mouse mammary tumour virus superantigen Ribosomal_L27e PF01777.13 EWM22601.1 - 5.1e-23 80.9 4.8 7.8e-23 80.4 3.4 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EWM22601.1 - 2.4e-06 27.0 1.3 2.4e-06 27.0 0.9 2.2 2 0 0 2 2 2 1 KOW motif Myb_DNA-binding PF00249.26 EWM22603.1 - 1.6e-13 50.4 0.2 2e-13 50.1 0.2 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EWM22603.1 - 3.2e-05 23.9 0.3 3.8e-05 23.6 0.2 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Annexin PF00191.15 EWM22603.1 - 0.1 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Annexin adh_short PF00106.20 EWM22604.1 - 6.4e-28 97.7 4.7 1.2e-27 96.8 3.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EWM22604.1 - 5.8e-27 95.0 2.0 7.3e-27 94.6 1.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EWM22604.1 - 1.6e-11 44.1 5.3 8.2e-11 41.8 3.7 1.9 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EWM22604.1 - 9.8e-06 24.6 0.3 1.5e-05 24.0 0.2 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 EWM22604.1 - 0.0008 19.1 1.0 0.0016 18.1 0.7 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 EWM22604.1 - 0.0016 17.9 1.0 0.0022 17.4 0.7 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PALP PF00291.20 EWM22604.1 - 0.0026 17.0 0.9 0.0047 16.1 0.3 1.6 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme 2-Hacid_dh_C PF02826.14 EWM22604.1 - 0.0092 15.1 0.2 0.019 14.1 0.1 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2CSK_N PF08521.5 EWM22604.1 - 0.059 12.8 0.7 0.099 12.1 0.5 1.3 1 0 0 1 1 1 0 Two-component sensor kinase N-terminal NAD_binding_7 PF13241.1 EWM22604.1 - 0.078 13.2 0.6 0.13 12.4 0.4 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding AdoHcyase_NAD PF00670.16 EWM22604.1 - 0.39 10.5 4.0 1.7 8.5 1.0 2.5 2 1 1 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Mito_carr PF00153.22 EWM22605.1 - 4e-58 193.1 0.0 6.2e-21 73.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Prenyltrans PF00432.16 EWM22605.1 - 0.094 12.2 0.1 0.094 12.2 0.1 2.7 3 0 0 3 3 3 0 Prenyltransferase and squalene oxidase repeat GTP_EFTU_D3 PF03143.12 EWM22606.1 - 1.3e-07 31.6 0.0 2.9e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU PF00009.22 EWM22606.1 - 2.5e-07 30.3 0.0 0.00034 20.0 0.0 2.6 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain START PF01852.14 EWM22607.1 - 2.9e-07 30.0 0.1 4.1e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 START domain Telethonin PF09470.5 EWM22607.1 - 0.018 14.4 0.1 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Telethonin protein Aminotran_1_2 PF00155.16 EWM22608.1 - 1.5e-33 116.2 0.0 1.7e-33 116.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EWM22608.1 - 0.0042 15.8 0.0 0.0062 15.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EWM22608.1 - 0.011 14.8 0.0 0.023 13.8 0.0 1.4 2 0 0 2 2 2 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EWM22608.1 - 0.022 13.8 0.0 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family FAD_binding_4 PF01565.18 EWM22609.1 - 9.5e-30 102.8 1.1 1.3e-29 102.3 0.3 1.6 2 0 0 2 2 2 1 FAD binding domain ALO PF04030.9 EWM22609.1 - 3.9e-26 92.1 0.0 1.6e-21 77.0 0.1 2.2 2 0 0 2 2 2 2 D-arabinono-1,4-lactone oxidase DUF2114 PF09887.4 EWM22609.1 - 0.26 9.5 0.0 0.38 9.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) Bax1-I PF01027.15 EWM22610.1 - 9.6e-37 126.5 20.0 1.5e-36 125.9 13.9 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 PMSR PF01625.16 EWM22611.1 - 3.1e-55 186.3 0.7 4.6e-55 185.7 0.5 1.2 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Aa_trans PF01490.13 EWM22612.1 - 9.1e-41 139.6 32.3 1.5e-40 138.9 21.6 1.8 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3713 PF12506.3 EWM22613.1 - 0.012 15.6 4.1 2.1 8.4 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3713) Methyltransf_18 PF12847.2 EWM22616.1 - 5.6e-09 36.5 0.1 9e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM22616.1 - 3.7e-07 29.8 0.1 5.8e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM22616.1 - 8.9e-07 28.9 0.1 1.6e-06 28.1 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 EWM22616.1 - 1.5e-05 24.3 0.0 2.4e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_12 PF08242.7 EWM22616.1 - 0.00043 20.6 0.0 0.00073 19.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM22616.1 - 0.00059 20.2 0.1 0.0013 19.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM22616.1 - 0.00079 19.7 0.1 0.0014 18.9 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EWM22616.1 - 0.001 18.5 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EWM22616.1 - 0.001 18.2 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 EWM22616.1 - 0.0011 18.1 0.0 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.7 EWM22616.1 - 0.005 16.2 0.1 0.0074 15.6 0.1 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_23 PF13489.1 EWM22616.1 - 0.018 14.7 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 EWM22616.1 - 0.035 13.1 0.0 0.046 12.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase TehB PF03848.9 EWM22616.1 - 0.15 11.2 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB CtaG_Cox11 PF04442.9 EWM22617.1 - 1.9e-59 199.7 0.3 2.5e-59 199.4 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 EAP30 PF04157.11 EWM22618.1 - 1.9e-59 200.5 0.4 2.2e-59 200.3 0.3 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family UPF0552 PF10574.4 EWM22618.1 - 0.076 12.4 0.1 0.12 11.7 0.0 1.5 1 1 0 1 1 1 0 Uncharacterised protein family UPF0552 Methyltransf_16 PF10294.4 EWM22619.1 - 2.9e-19 69.1 0.0 1.3e-09 37.7 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 EWM22619.1 - 6.3e-06 26.7 0.0 1.5e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM22619.1 - 5.3e-05 23.0 0.0 8.8e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM22619.1 - 0.00073 19.5 0.1 0.01 15.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EWM22619.1 - 0.001 18.5 0.0 0.0037 16.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.8 EWM22619.1 - 0.036 13.1 0.1 0.072 12.2 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) His_Phos_2 PF00328.17 EWM22620.1 - 3.7e-16 59.3 0.0 5.2e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 EWM22620.1 - 0.033 14.2 0.0 0.059 13.4 0.0 1.4 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) CRAL_TRIO PF00650.15 EWM22622.1 - 5e-25 87.8 0.0 6.2e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain Hydrolase PF00702.21 EWM22623.1 - 8.8e-14 52.4 0.4 0.00037 20.9 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EWM22623.1 - 1.5e-12 47.0 0.0 1.5e-12 47.0 0.0 2.6 3 0 0 3 3 3 1 E1-E2 ATPase HAD PF12710.2 EWM22623.1 - 2.4e-12 47.4 0.0 8.5e-12 45.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EWM22623.1 - 8.5e-10 38.4 0.0 2.2e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EWM22623.1 - 0.0099 15.4 0.0 0.025 14.1 0.0 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase tRNA-synt_1c PF00749.16 EWM22624.1 - 0.05 12.2 2.0 0.069 11.7 1.4 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain DUF463 PF04317.7 EWM22624.1 - 0.11 11.0 0.1 7 5.1 0.0 2.1 2 0 0 2 2 2 0 YcjX-like family, DUF463 Beta_elim_lyase PF01212.16 EWM22625.1 - 1.2e-84 283.8 0.0 2.4e-84 282.9 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EWM22625.1 - 2.5e-06 26.8 0.0 0.057 12.4 0.0 2.5 2 1 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family ERG4_ERG24 PF01222.12 EWM22626.1 - 1.5e-65 221.4 11.7 1.8e-65 221.2 8.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family TPR_16 PF13432.1 EWM22628.1 - 1.7e-18 66.7 12.4 0.0002 21.9 0.2 8.2 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.1 EWM22628.1 - 9.7e-18 63.5 8.5 0.00015 21.3 0.2 7.0 5 2 3 8 8 8 5 TPR repeat TPR_2 PF07719.12 EWM22628.1 - 3.8e-17 60.7 7.1 0.00083 19.0 0.0 8.6 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 EWM22628.1 - 4.4e-14 51.7 14.8 0.0072 16.8 0.0 7.4 6 2 4 10 10 9 4 Tetratricopeptide repeat TPR_1 PF00515.23 EWM22628.1 - 5.2e-14 51.1 2.0 0.00071 19.0 0.0 7.5 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 EWM22628.1 - 6.9e-13 48.7 7.5 0.00036 20.8 0.1 7.2 6 2 2 8 8 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 EWM22628.1 - 2.7e-12 45.5 0.0 0.0024 17.5 0.0 6.4 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 EWM22628.1 - 2.3e-10 40.2 13.7 0.26 11.2 0.0 7.3 5 1 3 8 8 8 5 Tetratricopeptide repeat Apc3 PF12895.2 EWM22628.1 - 3e-08 33.6 4.4 0.002 18.2 0.4 5.0 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.4 EWM22628.1 - 9.6e-08 32.0 0.2 0.22 11.4 0.0 4.5 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EWM22628.1 - 4.1e-07 29.6 0.1 0.56 10.5 0.0 5.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EWM22628.1 - 7.8e-06 25.3 2.0 4.8 7.2 0.0 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 EWM22628.1 - 6.6e-05 22.6 0.0 1.5 8.7 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EWM22628.1 - 0.0019 18.5 10.2 9.9 6.8 0.0 7.2 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_20 PF14561.1 EWM22628.1 - 0.089 12.9 2.6 0.42 10.7 0.1 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat ADH_zinc_N PF00107.21 EWM22629.1 - 2.3e-08 33.6 0.2 8.8e-08 31.7 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase XdhC_C PF13478.1 EWM22629.1 - 0.01 16.1 0.0 0.017 15.4 0.0 1.3 1 0 0 1 1 1 0 XdhC Rossmann domain ADH_zinc_N_2 PF13602.1 EWM22629.1 - 0.011 16.6 0.0 0.034 15.0 0.0 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 EWM22629.1 - 0.1 12.6 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_transf_20 PF00982.16 EWM22631.1 - 1.6e-102 343.4 0.0 1.1e-101 340.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EWM22631.1 - 2.3e-34 118.3 0.0 7.8e-34 116.6 0.0 1.8 2 0 0 2 2 2 1 Trehalose-phosphatase S6PP PF05116.8 EWM22631.1 - 0.00083 18.7 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.7 EWM22631.1 - 0.0045 16.5 0.0 0.034 13.7 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase His_Phos_2 PF00328.17 EWM22632.1 - 1.9e-26 93.2 0.0 1.2e-13 51.1 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 EWM22632.1 - 8e-05 22.7 0.0 0.00014 22.0 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Trehalase PF01204.13 EWM22633.1 - 1.4e-132 442.9 0.0 1.8e-132 442.6 0.0 1.1 1 0 0 1 1 1 1 Trehalase Phos_pyr_kin PF08543.7 EWM22634.1 - 1.1e-17 64.1 0.0 1.6e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EWM22634.1 - 3.5e-14 52.6 0.1 4e-12 45.8 0.0 2.7 3 0 0 3 3 3 2 pfkB family carbohydrate kinase Hydrolase PF00702.21 EWM22634.1 - 7.3e-07 29.8 0.0 0.012 16.0 0.0 3.3 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EWM22634.1 - 0.00012 22.2 0.0 0.00051 20.2 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Carb_kinase PF01256.12 EWM22634.1 - 0.097 11.9 0.0 0.43 9.8 0.0 1.9 2 0 0 2 2 2 0 Carbohydrate kinase Ribosomal_S19 PF00203.16 EWM22635.1 - 5.7e-25 86.7 0.2 8.9e-25 86.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 zf-UBR PF02207.15 EWM22636.1 - 1.8e-15 56.4 17.1 3.6e-15 55.4 11.8 1.5 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 EWM22636.1 - 2.2e-08 33.6 0.0 4.8e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS CRAL_TRIO PF00650.15 EWM22637.1 - 5.4e-22 77.9 0.0 8.8e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EWM22637.1 - 0.00078 19.3 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CPL PF08144.6 EWM22638.1 - 2.8e-05 24.0 0.3 0.0013 18.6 0.0 3.0 3 0 0 3 3 3 1 CPL (NUC119) domain PUF PF00806.14 EWM22638.1 - 0.046 13.2 0.0 4 7.1 0.0 3.0 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat RF-1 PF00472.15 EWM22640.1 - 2.3e-21 75.7 1.7 3.3e-21 75.2 1.2 1.2 1 0 0 1 1 1 1 RF-1 domain DUF641 PF04859.7 EWM22640.1 - 0.18 11.5 3.6 0.28 10.9 2.5 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) CorA PF01544.13 EWM22642.1 - 0.00056 19.0 1.3 0.00056 19.0 0.9 2.3 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein FUSC PF04632.7 EWM22642.1 - 0.0018 16.7 1.3 0.0025 16.3 0.9 1.1 1 0 0 1 1 1 1 Fusaric acid resistance protein family Rtf2 PF04641.7 EWM22642.1 - 0.017 14.3 3.5 0.023 13.9 2.5 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Med15 PF09606.5 EWM22642.1 - 0.066 11.4 12.5 0.078 11.1 8.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FCP1_C PF09309.5 EWM22642.1 - 0.078 12.2 3.8 0.1 11.8 2.6 1.2 1 0 0 1 1 1 0 FCP1, C-terminal I_LWEQ PF01608.12 EWM22642.1 - 8.7 6.2 11.7 17 5.3 8.1 1.4 1 0 0 1 1 1 0 I/LWEQ domain zf-CW PF07496.10 EWM22643.1 - 0.0012 18.5 0.3 0.0024 17.5 0.2 1.5 1 0 0 1 1 1 1 CW-type Zinc Finger DUF35_N PF12172.3 EWM22643.1 - 0.04 13.8 2.2 0.073 13.0 0.2 2.2 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Mito_fiss_reg PF05308.6 EWM22643.1 - 8.5 5.6 10.5 13 5.0 7.2 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator NAD_binding_8 PF13450.1 EWM22644.1 - 3.9e-11 42.8 0.6 8.1e-11 41.7 0.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EWM22644.1 - 3.7e-10 39.2 5.9 1.3e-08 34.1 4.1 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EWM22644.1 - 8.2e-08 31.6 0.7 3.6e-07 29.5 0.1 1.9 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 EWM22644.1 - 2.4e-06 26.8 0.0 4.9e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EWM22644.1 - 6.4e-06 25.2 5.0 3.2e-05 22.9 1.5 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 EWM22644.1 - 2.5e-05 23.4 0.2 4.1e-05 22.8 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EWM22644.1 - 6e-05 23.3 2.4 0.0014 18.9 0.7 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EWM22644.1 - 0.00014 21.8 0.1 0.00038 20.3 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EWM22644.1 - 0.00017 20.7 0.8 0.00059 19.0 0.4 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 EWM22644.1 - 0.00063 18.3 0.3 0.00097 17.7 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 EWM22644.1 - 0.0014 17.6 1.5 0.0023 16.8 1.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EWM22644.1 - 0.0014 18.7 0.1 0.0029 17.6 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 EWM22644.1 - 0.0021 17.2 0.6 0.018 14.2 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase Trp_halogenase PF04820.9 EWM22644.1 - 0.01 14.5 0.5 0.01 14.5 0.3 1.7 2 0 0 2 2 2 0 Tryptophan halogenase 2-Hacid_dh_C PF02826.14 EWM22644.1 - 0.035 13.2 0.2 0.99 8.5 0.1 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain YjeF_N PF03853.10 EWM22644.1 - 0.062 12.9 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 YjeF-related protein N-terminus Lycopene_cycl PF05834.7 EWM22644.1 - 0.069 12.0 0.4 0.29 10.0 0.1 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.9 EWM22644.1 - 0.15 11.4 0.1 0.29 10.5 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Proteasome PF00227.21 EWM22645.1 - 1.3e-26 93.0 0.0 1.6e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Aldose_epim PF01263.15 EWM22646.1 - 4.2e-37 127.8 0.1 6.8e-37 127.1 0.0 1.3 1 1 0 1 1 1 1 Aldose 1-epimerase FLO_LFY PF01698.11 EWM22647.1 - 0.0062 15.4 1.7 0.011 14.6 1.2 1.4 1 0 0 1 1 1 1 Floricaula / Leafy protein Proteasome PF00227.21 EWM22648.1 - 2.4e-52 177.0 0.3 3e-52 176.6 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit RRM_1 PF00076.17 EWM22649.1 - 1.5e-20 72.5 0.0 3.1e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM22649.1 - 2.8e-16 59.2 0.0 5.6e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.3 EWM22649.1 - 3.7e-12 46.4 1.5 3.7e-12 46.4 1.0 1.7 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_5 PF13893.1 EWM22649.1 - 2.2e-10 40.2 0.0 3.9e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1777 PF08648.7 EWM22649.1 - 4.5 6.9 37.2 0.85 9.3 22.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) COG6 PF06419.6 EWM22650.1 - 1.6e-87 294.1 0.0 2.1e-87 293.7 0.0 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 GAS PF13851.1 EWM22650.1 - 0.034 13.3 0.0 0.078 12.1 0.0 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Methyltransf_26 PF13659.1 EWM22651.1 - 0.0032 17.5 0.1 0.0084 16.1 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Hist_deacetyl PF00850.14 EWM22653.1 - 8.3e-52 176.4 0.0 1.2e-51 175.9 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Trehalase PF01204.13 EWM22654.1 - 6e-140 467.2 0.0 7.1e-140 467.0 0.0 1.0 1 0 0 1 1 1 1 Trehalase OTU PF02338.14 EWM22655.1 - 1.3e-11 45.1 0.1 1.1e-10 42.2 0.0 2.4 1 1 0 1 1 1 1 OTU-like cysteine protease MAPEG PF01124.13 EWM22656.1 - 0.012 15.2 0.2 0.015 14.8 0.1 1.2 1 0 0 1 1 1 0 MAPEG family CWC25 PF12542.3 EWM22657.1 - 1.1e-15 57.8 3.1 1.1e-15 57.8 2.1 4.8 3 1 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 EWM22657.1 - 6.9e-12 45.1 8.9 6.9e-12 45.1 6.1 6.3 5 3 0 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR WD40 PF00400.27 EWM22658.1 - 2.5e-41 138.1 7.2 4.3e-08 32.7 0.0 6.3 5 1 1 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EWM22658.1 - 1.3e-07 31.5 0.1 0.0012 18.5 0.0 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A IPPT PF01715.12 EWM22660.1 - 4.2e-59 199.6 0.0 1.3e-58 198.0 0.0 1.7 2 0 0 2 2 2 1 IPP transferase IPT PF01745.11 EWM22660.1 - 1.1e-05 24.6 0.1 0.00017 20.8 0.0 2.2 2 0 0 2 2 2 1 Isopentenyl transferase AAA_17 PF13207.1 EWM22660.1 - 0.0097 16.7 1.4 0.046 14.5 0.0 2.8 2 2 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EWM22660.1 - 0.011 14.8 0.0 0.024 13.7 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 EWM22660.1 - 0.02 14.7 1.6 0.08 12.8 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EWM22660.1 - 0.036 13.4 0.0 0.12 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EWM22660.1 - 0.038 13.8 0.0 0.083 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2840 PF11000.3 EWM22660.1 - 0.044 13.3 0.3 0.15 11.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2840) AAA_16 PF13191.1 EWM22660.1 - 0.051 13.5 1.4 0.068 13.1 0.0 2.0 2 2 1 3 3 3 0 AAA ATPase domain Mg_chelatase PF01078.16 EWM22660.1 - 0.079 12.1 0.0 0.2 10.7 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zn_clus PF00172.13 EWM22661.1 - 2.7e-08 33.5 11.2 5.8e-08 32.5 7.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TB2_DP1_HVA22 PF03134.14 EWM22663.1 - 2.8e-35 119.9 6.0 5.2e-35 119.0 4.2 1.5 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF3816 PF12822.2 EWM22663.1 - 0.0076 16.1 0.3 0.012 15.5 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3816) BH3 PF15285.1 EWM22664.1 - 0.074 12.5 1.7 0.32 10.5 0.4 2.5 2 0 0 2 2 2 0 Beclin-1 BH3 domain, Bcl-2-interacting AAA_16 PF13191.1 EWM22665.1 - 2.9e-06 27.3 0.2 9.7e-06 25.6 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 EWM22665.1 - 1.1e-05 24.4 0.0 2.2e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.7 EWM22665.1 - 3.9e-05 23.3 0.1 0.00044 19.9 0.1 2.3 1 1 0 1 1 1 1 NACHT domain LRR_6 PF13516.1 EWM22665.1 - 8e-05 22.3 4.5 1.9 8.8 0.0 5.4 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.2 EWM22665.1 - 0.0013 18.2 5.8 0.67 9.6 0.1 3.2 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) AAA_25 PF13481.1 EWM22665.1 - 0.092 12.1 0.2 0.87 8.9 0.1 2.6 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EWM22665.1 - 0.12 12.5 1.2 1 9.4 0.1 2.9 2 1 0 2 2 2 0 AAA domain PBP1_TM PF14812.1 EWM22665.1 - 1.7 9.0 5.4 4.9 7.5 3.8 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TCR PF03638.10 EWM22666.1 - 5e-28 96.6 47.8 3.8e-14 52.2 13.8 2.6 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain UPF0066 PF01980.11 EWM22667.1 - 3.2e-37 127.1 0.0 1e-36 125.4 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised protein family UPF0066 TBPIP PF07106.8 EWM22668.1 - 1.2 8.6 16.7 0.22 11.0 4.2 2.6 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Bacillus_HBL PF05791.6 EWM22668.1 - 2.7 7.3 6.1 21 4.4 0.3 3.2 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DEAD PF00270.24 EWM22669.1 - 2e-16 59.9 0.0 1.2e-15 57.3 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EWM22669.1 - 2.3e-10 40.1 0.0 5.2e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HHH_5 PF14520.1 EWM22669.1 - 0.00049 20.2 0.1 0.0019 18.3 0.1 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix domain DOT1 PF08123.8 EWM22671.1 - 1.6e-08 34.1 0.0 7.7e-08 31.8 0.0 1.9 2 0 0 2 2 2 1 Histone methylation protein DOT1 GHMP_kinases_C PF08544.8 EWM22671.1 - 0.065 13.4 0.1 0.33 11.1 0.0 2.1 2 0 0 2 2 2 0 GHMP kinases C terminal DOT1 PF08123.8 EWM22672.1 - 1.6e-08 34.0 0.0 7.8e-08 31.8 0.0 1.9 2 0 0 2 2 2 1 Histone methylation protein DOT1 GHMP_kinases_C PF08544.8 EWM22672.1 - 0.065 13.4 0.1 0.34 11.1 0.0 2.1 2 0 0 2 2 2 0 GHMP kinases C terminal DOT1 PF08123.8 EWM22673.1 - 1.3e-08 34.4 0.0 6.6e-08 32.1 0.0 1.9 2 0 0 2 2 2 1 Histone methylation protein DOT1 GHMP_kinases_C PF08544.8 EWM22673.1 - 0.05 13.8 0.1 0.29 11.3 0.0 2.1 2 0 0 2 2 2 0 GHMP kinases C terminal Arf PF00025.16 EWM22674.1 - 4e-48 162.9 0.0 5.1e-48 162.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EWM22674.1 - 7.9e-12 44.8 0.0 1e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EWM22674.1 - 1.6e-10 41.4 0.0 2.2e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 EWM22674.1 - 3.2e-10 39.2 0.2 6.6e-06 25.0 0.0 2.4 1 1 0 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EWM22674.1 - 3.3e-06 26.4 0.0 4.3e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EWM22674.1 - 4.7e-05 22.6 0.0 5.2e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EWM22674.1 - 0.00025 21.0 0.0 0.00084 19.2 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EWM22674.1 - 0.0049 16.3 0.1 0.28 10.5 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF35_N PF12172.3 EWM22675.1 - 0.12 12.3 3.4 0.16 11.8 0.8 2.0 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Cpn60_TCP1 PF00118.19 EWM22676.1 - 1e-131 439.9 1.8 1.2e-131 439.7 1.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family G-patch PF01585.18 EWM22678.1 - 1.1e-07 31.5 2.2 1.1e-07 31.5 1.6 1.9 2 0 0 2 2 2 1 G-patch domain RRM_5 PF13893.1 EWM22678.1 - 4.9e-06 26.2 0.1 8.2e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EWM22678.1 - 2.7e-05 23.7 0.1 4.6e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM22678.1 - 0.065 13.2 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FAD_binding_3 PF01494.14 EWM22679.1 - 8.3e-74 248.7 0.0 1.3e-73 248.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EWM22679.1 - 0.024 13.7 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.1 EWM22679.1 - 0.055 13.4 0.0 0.16 11.9 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ThiF PF00899.16 EWM22679.1 - 0.06 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 ThiF family Peptidase_C97 PF05903.9 EWM22680.1 - 6.8e-32 110.3 0.0 9.6e-32 109.8 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain CoA_binding_2 PF13380.1 EWM22681.1 - 2.6e-29 101.7 0.0 3e-29 101.5 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.14 EWM22681.1 - 0.00013 22.3 0.0 0.00019 21.9 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain DUF1218 PF06749.7 EWM22682.1 - 0.13 12.7 1.4 0.25 11.8 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1218) PPR_2 PF13041.1 EWM22683.1 - 1.1e-29 102.0 0.0 3.4e-08 33.3 0.0 7.6 3 1 5 8 8 8 6 PPR repeat family PPR_3 PF13812.1 EWM22683.1 - 2.2e-27 92.9 18.0 0.00043 20.3 0.0 9.2 9 0 0 9 9 9 7 Pentatricopeptide repeat domain PPR PF01535.15 EWM22683.1 - 1.1e-26 90.9 11.6 0.00029 20.6 0.0 8.8 10 0 0 10 10 10 6 PPR repeat PPR_1 PF12854.2 EWM22683.1 - 1.8e-22 78.4 0.0 0.00082 18.8 0.0 6.5 6 0 0 6 6 6 4 PPR repeat RRM_1 PF00076.17 EWM22685.1 - 1.3e-15 56.7 0.0 7.2e-15 54.3 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM22685.1 - 7.3e-08 32.2 0.0 2.8e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ThiF PF00899.16 EWM22686.1 - 2.1e-48 163.5 0.7 3.2e-33 114.4 0.0 3.0 3 0 0 3 3 3 2 ThiF family UBACT PF02134.16 EWM22686.1 - 7.4e-32 108.7 0.2 1.6e-25 88.4 0.1 2.5 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EWM22686.1 - 2.9e-18 64.9 0.1 5.2e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UBA_e1_C PF09358.5 EWM22686.1 - 2.8e-09 37.2 0.0 9.9e-09 35.4 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain PAP_fibrillin PF04755.7 EWM22687.1 - 1.5e-27 96.6 0.0 2.6e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 PAP_fibrillin adh_short PF00106.20 EWM22688.1 - 9.1e-27 93.9 1.0 1.5e-26 93.2 0.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EWM22688.1 - 2.5e-10 40.5 0.0 3.3e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EWM22688.1 - 8e-09 35.4 0.3 1.3e-08 34.7 0.2 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EWM22688.1 - 3.7e-08 33.5 0.2 1e-07 32.1 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EWM22688.1 - 0.00038 19.7 0.0 0.0049 16.0 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EWM22688.1 - 0.003 17.0 0.0 0.0063 15.9 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Lum_binding PF00677.12 EWM22689.1 - 5.1e-35 119.2 0.1 3.1e-16 59.0 0.0 2.3 2 0 0 2 2 2 2 Lumazine binding domain Ins_P5_2-kin PF06090.7 EWM22690.1 - 8.4e-41 140.0 0.0 9.8e-41 139.7 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Ribosomal_L7Ae PF01248.21 EWM22691.1 - 1.9e-12 46.5 0.1 4.4e-12 45.3 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EWM22691.1 - 0.00013 21.8 0.0 0.00028 20.7 0.0 1.5 2 0 0 2 2 2 1 RNase P subunit Pop3 AAA_16 PF13191.1 EWM22693.1 - 6.1e-05 23.0 0.5 0.00031 20.7 0.4 2.2 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.22 EWM22693.1 - 0.0004 20.7 0.0 0.0015 18.8 0.0 1.9 2 0 0 2 2 2 1 ABC transporter DUF258 PF03193.11 EWM22693.1 - 0.0017 17.5 0.0 0.0028 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EWM22693.1 - 0.0018 18.3 0.0 0.0048 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EWM22693.1 - 0.002 17.6 0.0 0.0042 16.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EWM22693.1 - 0.0049 16.2 0.0 0.0096 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EWM22693.1 - 0.0081 15.8 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain cobW PF02492.14 EWM22693.1 - 0.011 15.1 0.1 0.019 14.4 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EWM22693.1 - 0.013 15.4 0.2 0.086 12.7 0.3 2.3 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EWM22693.1 - 0.023 14.3 0.1 0.057 12.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EWM22693.1 - 0.028 13.5 0.0 0.052 12.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.18 EWM22693.1 - 0.044 13.7 0.0 0.086 12.8 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.9 EWM22693.1 - 0.046 13.4 0.5 0.14 11.8 0.1 2.1 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 EWM22693.1 - 0.056 13.1 0.0 0.091 12.4 0.0 1.3 1 0 0 1 1 1 0 NTPase T2SE PF00437.15 EWM22693.1 - 0.066 12.0 0.0 0.21 10.4 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.1 EWM22693.1 - 0.068 12.9 0.6 0.19 11.4 0.1 2.0 2 0 0 2 2 2 0 Part of AAA domain MobB PF03205.9 EWM22693.1 - 0.08 12.6 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Guanylate_kin PF00625.16 EWM22693.1 - 0.14 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Guanylate kinase AAA_10 PF12846.2 EWM22693.1 - 0.15 11.4 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain GTP_EFTU PF00009.22 EWM22693.1 - 0.17 11.3 0.0 0.74 9.2 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 EWM22693.1 - 0.18 11.3 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DAP3 PF10236.4 EWM22693.1 - 0.18 10.6 0.0 0.33 9.8 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DnaJ PF00226.26 EWM22695.1 - 7.6e-22 76.8 0.1 1.1e-21 76.2 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EWM22695.1 - 8.6e-06 25.5 0.0 0.013 15.3 0.0 3.0 2 1 0 2 2 2 2 DnaJ C terminal domain Tex_N PF09371.5 EWM22699.1 - 0.00012 21.4 0.0 0.00022 20.5 0.0 1.4 1 1 0 1 1 1 1 Tex-like protein N-terminal domain Complex1_LYR_1 PF13232.1 EWM22699.1 - 0.059 13.5 1.3 0.12 12.5 0.2 1.8 2 0 0 2 2 2 0 Complex1_LYR-like Complex1_LYR PF05347.10 EWM22699.1 - 0.075 12.8 2.5 0.087 12.6 0.4 1.9 2 0 0 2 2 2 0 Complex 1 protein (LYR family) SMC_N PF02463.14 EWM22700.1 - 0.0042 16.3 0.0 0.005 16.0 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain Guanylate_kin PF00625.16 EWM22701.1 - 7.3e-05 22.2 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 Guanylate kinase Guanylate_kin PF00625.16 EWM22702.1 - 7.3e-05 22.2 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 Guanylate kinase ABC_membrane PF00664.18 EWM22704.1 - 3.3e-27 95.6 6.8 4.5e-27 95.1 4.7 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EWM22704.1 - 1.2e-08 35.2 0.1 2.3e-08 34.4 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_17 PF13207.1 EWM22704.1 - 3.2e-05 24.7 0.1 5.6e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EWM22704.1 - 0.0027 17.6 0.7 0.0096 15.9 0.2 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.1 EWM22704.1 - 0.0066 16.4 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EWM22704.1 - 0.0095 15.1 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 EWM22704.1 - 0.041 14.1 0.1 0.073 13.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EWM22704.1 - 0.052 13.6 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EWM22704.1 - 0.052 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 EWM22704.1 - 0.06 12.8 0.1 0.16 11.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ArgK PF03308.11 EWM22704.1 - 0.063 12.0 0.1 0.23 10.2 0.0 1.8 2 0 0 2 2 2 0 ArgK protein AAA_10 PF12846.2 EWM22704.1 - 0.069 12.5 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain FtsK_SpoIIIE PF01580.13 EWM22704.1 - 0.07 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family ATP-synt_ab PF00006.20 EWM22704.1 - 0.078 12.4 0.1 0.34 10.3 0.0 1.9 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.1 EWM22704.1 - 0.088 12.2 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 EWM22704.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 Creatinase_N PF01321.13 EWM22705.1 - 1.9e-18 67.2 0.0 2.3e-18 66.9 0.0 1.0 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain DUF4192 PF13830.1 EWM22705.1 - 0.034 13.7 0.1 0.044 13.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) ABC_membrane_2 PF06472.10 EWM22706.1 - 3e-05 23.2 0.1 0.00071 18.7 0.0 2.0 2 0 0 2 2 2 2 ABC transporter transmembrane region 2 Ank_5 PF13857.1 EWM22708.1 - 0.0013 18.9 0.1 0.0035 17.5 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EWM22708.1 - 0.0062 17.0 0.0 0.014 15.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EWM22708.1 - 0.019 14.7 0.1 0.13 12.1 0.0 2.4 2 1 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.1 EWM22708.1 - 0.061 13.6 0.1 3.3 8.2 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeat Ank_2 PF12796.2 EWM22708.1 - 0.071 13.4 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) NAD_binding_8 PF13450.1 EWM22709.1 - 3.2e-10 39.8 0.0 6.5e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EWM22709.1 - 1.2e-05 24.4 0.0 1.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EWM22709.1 - 3e-05 22.6 0.0 3.9e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.1 EWM22709.1 - 0.00036 20.3 0.0 0.0022 17.7 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EWM22709.1 - 0.00043 20.2 0.0 0.00058 19.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EWM22709.1 - 0.0031 16.6 0.0 0.0052 15.9 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.19 EWM22709.1 - 0.0074 15.3 0.3 0.05 12.6 0.0 1.9 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase Semialdhyde_dh PF01118.19 EWM22709.1 - 0.014 15.7 0.0 0.5 10.6 0.0 2.2 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 EWM22709.1 - 0.018 15.1 0.0 0.037 14.0 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EWM22709.1 - 0.034 12.9 0.2 0.05 12.4 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 EWM22709.1 - 0.067 12.0 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein OCD_Mu_crystall PF02423.10 EWM22709.1 - 0.075 11.7 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family MFS_1 PF07690.11 EWM22710.1 - 1.3e-24 86.6 17.7 1.3e-24 86.6 12.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EWM22710.1 - 3.6e-08 32.4 0.9 3.6e-08 32.4 0.6 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 EWM22710.1 - 8e-05 20.8 0.2 0.043 11.8 0.0 2.5 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Tudor-knot PF11717.3 EWM22711.1 - 0.0008 19.0 0.2 0.0013 18.4 0.1 1.3 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain MBT PF02820.13 EWM22711.1 - 0.052 13.4 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 mbt repeat eIF-4B PF06273.6 EWM22711.1 - 2.1 6.9 5.3 2.7 6.6 3.7 1.2 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B MIT PF04212.13 EWM22712.1 - 5.8e-15 54.9 0.9 9.7e-15 54.2 0.6 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Cyclase_polyket PF04673.7 EWM22712.1 - 0.093 12.7 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Polyketide synthesis cyclase UCH PF00443.24 EWM22713.1 - 1.4e-23 83.3 0.0 9.3e-16 57.7 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EWM22713.1 - 3.4e-07 29.9 0.0 0.00026 20.5 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase adh_short PF00106.20 EWM22715.1 - 1.5e-17 64.0 0.3 3.7e-16 59.4 0.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EWM22715.1 - 5.1e-05 23.0 0.1 0.00011 21.9 0.0 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EWM22715.1 - 0.00027 20.7 0.0 0.00038 20.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EWM22715.1 - 0.13 12.0 0.3 0.55 10.0 0.0 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Chloroa_b-bind PF00504.16 EWM22717.1 - 1.3e-41 142.4 0.1 1.9e-41 141.9 0.1 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DUF788 PF05620.6 EWM22718.1 - 0.03 14.1 0.3 0.049 13.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF788) ATP-synt_F6 PF05511.6 EWM22720.1 - 0.14 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 DRMBL PF07522.9 EWM22722.1 - 4.6e-18 65.2 0.0 7.5e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EWM22722.1 - 0.1 12.0 0.0 0.24 10.9 0.0 1.6 2 0 0 2 2 2 0 Beta-lactamase superfamily domain RMMBL PF07521.7 EWM22722.1 - 0.13 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 RNA-metabolising metallo-beta-lactamase Sod_Cu PF00080.15 EWM22723.1 - 5.1e-25 88.2 0.2 6.3e-25 87.9 0.2 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Syntaxin-6_N PF09177.6 EWM22724.1 - 2.5e-05 24.5 0.8 7.4e-05 23.0 0.0 2.2 3 0 0 3 3 3 1 Syntaxin 6, N-terminal SNARE PF05739.14 EWM22724.1 - 0.0091 15.6 4.0 0.0091 15.6 2.8 2.2 2 0 0 2 2 2 1 SNARE domain Cob_adeno_trans PF01923.13 EWM22724.1 - 0.066 12.9 0.3 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 Cobalamin adenosyltransferase Use1 PF09753.4 EWM22724.1 - 0.12 11.7 0.1 0.41 10.0 0.0 1.8 2 0 0 2 2 2 0 Membrane fusion protein Use1 Ibs_toxin PF13956.1 EWM22724.1 - 0.64 9.8 6.7 1.3 8.9 4.6 1.5 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system PspB PF06667.7 EWM22724.1 - 2.7 8.0 0.0 2.7 8.0 0.0 2.8 3 0 0 3 3 3 0 Phage shock protein B Carboxyl_trans PF01039.17 EWM22725.1 - 3.8e-33 114.5 0.3 5.5e-33 114.0 0.1 1.3 2 0 0 2 2 2 1 Carboxyl transferase domain Voltage_CLC PF00654.15 EWM22726.1 - 0.19 10.6 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 Voltage gated chloride channel Voltage_CLC PF00654.15 EWM22727.1 - 0.19 10.6 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 Voltage gated chloride channel PB1 PF00564.19 EWM22728.1 - 0.00028 20.4 0.0 0.00042 19.9 0.0 1.3 1 0 0 1 1 1 1 PB1 domain Methyltransf_18 PF12847.2 EWM22731.1 - 1.1e-05 25.9 0.7 2.6e-05 24.7 0.5 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM22731.1 - 5.2e-05 22.8 0.1 0.0001 21.9 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM22731.1 - 0.00013 22.0 0.0 0.0002 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM22731.1 - 0.003 17.8 0.1 0.016 15.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM22731.1 - 0.011 16.2 0.0 0.028 14.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 EWM22731.1 - 0.014 14.7 0.1 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DOT1 PF08123.8 EWM22731.1 - 0.016 14.5 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_12 PF08242.7 EWM22731.1 - 0.051 14.0 0.2 0.14 12.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 EWM22731.1 - 0.072 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.12 EWM22731.1 - 0.078 12.0 1.9 0.096 11.7 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_18 PF12847.2 EWM22732.1 - 1.1e-05 25.9 0.7 2.6e-05 24.7 0.5 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM22732.1 - 5.1e-05 22.8 0.1 0.0001 21.9 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM22732.1 - 0.00013 22.0 0.0 0.0002 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM22732.1 - 0.003 17.8 0.1 0.016 15.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM22732.1 - 0.011 16.2 0.0 0.027 14.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 EWM22732.1 - 0.014 14.7 0.1 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DOT1 PF08123.8 EWM22732.1 - 0.016 14.5 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_12 PF08242.7 EWM22732.1 - 0.051 14.0 0.2 0.14 12.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 EWM22732.1 - 0.071 12.4 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.12 EWM22732.1 - 0.078 12.0 1.9 0.096 11.7 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase AA_permease_2 PF13520.1 EWM22735.1 - 8.5e-11 41.0 10.2 9.9e-11 40.8 7.0 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1774 PF08611.5 EWM22735.1 - 0.38 10.9 5.5 1 9.5 1.9 2.2 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1774) Methyltransf_21 PF05050.7 EWM22736.1 - 1.1e-12 48.2 0.0 1.4e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain NUC153 PF08159.7 EWM22736.1 - 0.11 12.1 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 NUC153 domain TRAM_LAG1_CLN8 PF03798.11 EWM22737.1 - 7.1e-13 48.5 5.0 4.4e-12 45.9 3.5 2.0 1 1 0 1 1 1 1 TLC domain COX7C PF02935.11 EWM22737.1 - 0.31 10.8 0.1 0.31 10.8 0.0 2.5 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc Glutaredoxin PF00462.19 EWM22738.1 - 6.8e-19 67.6 0.0 1.1e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 EWM22738.1 - 0.00026 21.1 0.0 0.00046 20.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EWM22738.1 - 0.053 13.5 0.0 0.095 12.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain SH3BGR PF04908.10 EWM22738.1 - 0.057 13.3 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein MAPKK1_Int PF08923.5 EWM22740.1 - 5.4e-14 51.8 0.0 6.7e-13 48.3 0.0 2.3 2 1 0 2 2 2 1 Mitogen-activated protein kinase kinase 1 interacting Robl_LC7 PF03259.12 EWM22740.1 - 0.026 14.0 0.0 0.054 13.0 0.0 1.7 1 1 0 1 1 1 0 Roadblock/LC7 domain DUF1517 PF07466.6 EWM22741.1 - 9.1e-14 51.1 7.4 1e-13 50.9 4.5 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF1517) RDD PF06271.7 EWM22743.1 - 0.0063 16.4 0.1 4.9 7.0 0.0 2.1 1 1 1 2 2 2 2 RDD family DUF4131 PF13567.1 EWM22743.1 - 7.5 5.9 7.0 15 4.9 4.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Chromate_transp PF02417.10 EWM22744.1 - 1.1e-65 220.3 39.5 1.2e-33 116.1 4.8 2.6 3 0 0 3 3 3 2 Chromate transporter Cation_efflux PF01545.16 EWM22744.1 - 0.045 12.8 15.4 0.66 8.9 2.9 3.2 2 1 0 2 2 2 0 Cation efflux family DUF2648 PF10855.3 EWM22744.1 - 0.14 11.6 2.8 3.8 7.0 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2648) CcmH PF03918.9 EWM22744.1 - 0.23 10.4 0.6 1.5 7.7 0.0 2.5 2 0 0 2 2 2 0 Cytochrome C biogenesis protein DUF455 PF04305.9 EWM22745.1 - 1.2e-59 201.7 0.0 1.3e-59 201.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF455) zf-Tim10_DDP PF02953.10 EWM22746.1 - 9.7e-18 63.2 5.6 1.2e-17 62.9 3.9 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Herpes_BLRF2 PF05812.7 EWM22746.1 - 0.0016 18.2 0.2 0.0016 18.2 0.1 1.2 1 0 0 1 1 1 1 Herpesvirus BLRF2 protein DUF842 PF05811.8 EWM22746.1 - 0.0039 16.6 4.1 0.0049 16.3 2.8 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Condensin2nSMC PF12422.3 EWM22746.1 - 0.075 12.7 0.3 0.085 12.6 0.2 1.1 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit DUF3500 PF12006.3 EWM22746.1 - 0.078 11.8 0.1 0.086 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3500) Vicilin_N PF04702.7 EWM22746.1 - 0.1 12.1 1.8 0.12 11.9 1.3 1.1 1 0 0 1 1 1 0 Vicilin N terminal region ThiF PF00899.16 EWM22746.1 - 0.11 12.2 0.1 0.13 12.0 0.1 1.0 1 0 0 1 1 1 0 ThiF family zf-Tim10_DDP PF02953.10 EWM22747.1 - 1.7e-17 62.4 5.6 3.2e-17 61.5 3.9 1.5 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Herpes_BLRF2 PF05812.7 EWM22747.1 - 0.00088 19.0 0.2 0.001 18.8 0.1 1.3 1 0 0 1 1 1 1 Herpesvirus BLRF2 protein DUF842 PF05811.8 EWM22747.1 - 0.0088 15.5 4.2 0.013 14.9 2.9 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) DUF3500 PF12006.3 EWM22747.1 - 0.013 14.4 0.0 0.015 14.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3500) MgtE_N PF03448.12 EWM22747.1 - 0.08 13.2 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 MgtE intracellular N domain Condensin2nSMC PF12422.3 EWM22747.1 - 0.12 12.1 0.1 0.12 12.0 0.1 1.1 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit Herpes_LMP2 PF07415.6 EWM22748.1 - 0.1 11.1 6.1 0.15 10.5 4.2 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein EMP24_GP25L PF01105.19 EWM22748.1 - 0.75 9.4 2.4 0.96 9.1 0.1 2.2 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD Med9 PF07544.8 EWM22748.1 - 1.3 8.7 5.1 33 4.3 0.0 3.4 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Ank PF00023.25 EWM22749.1 - 8.4e-06 25.3 0.0 1.4e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.1 EWM22749.1 - 1.5e-05 25.0 0.0 2.7e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM22749.1 - 4.9e-05 23.1 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 EWM22749.1 - 0.00029 21.1 0.0 0.00052 20.2 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EWM22749.1 - 0.00073 19.9 0.0 0.12 12.9 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) CMS1 PF14617.1 EWM22749.1 - 0.033 13.2 2.8 0.045 12.8 1.9 1.1 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF581 PF04570.9 EWM22749.1 - 0.045 13.0 2.0 0.089 12.0 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF581) FLO_LFY PF01698.11 EWM22749.1 - 0.37 9.6 7.4 0.46 9.2 5.1 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein MIP-T3 PF10243.4 EWM22749.1 - 1.5 7.1 15.9 1.9 6.8 11.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 U79_P34 PF03064.11 EWM22749.1 - 5.4 6.4 16.2 8.9 5.7 11.2 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 RPAP2_Rtr1 PF04181.8 EWM22749.1 - 8.4 6.5 8.8 34 4.6 6.1 1.9 1 1 0 1 1 1 0 Rtr1/RPAP2 family BLVR PF06375.6 EWM22749.1 - 8.7 6.1 13.2 13 5.5 9.2 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) ABC_membrane PF00664.18 EWM22750.1 - 5.7e-47 160.4 0.9 9e-47 159.7 0.6 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EWM22750.1 - 1.8e-27 96.2 0.0 3.4e-27 95.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EWM22750.1 - 6e-07 28.9 0.0 0.00047 19.4 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_5 PF07728.9 EWM22750.1 - 0.0013 18.4 0.0 0.45 10.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 EWM22750.1 - 0.002 17.6 0.0 0.0061 16.0 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EWM22750.1 - 0.0037 17.2 0.1 2.6 7.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EWM22750.1 - 0.018 15.1 0.1 0.78 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EWM22750.1 - 0.022 13.9 0.0 0.058 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EWM22750.1 - 0.028 14.4 4.2 0.066 13.1 1.6 2.4 2 1 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 EWM22750.1 - 0.037 14.2 0.2 5.6 7.1 0.0 2.7 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EWM22750.1 - 0.038 13.3 0.1 17 4.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain Sigma54_activ_2 PF14532.1 EWM22750.1 - 0.065 13.2 0.0 0.32 11.0 0.0 2.1 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_17 PF13207.1 EWM22750.1 - 0.067 14.0 0.0 0.21 12.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain PLAC8 PF04749.12 EWM22752.1 - 1.5e-16 60.8 1.8 1.5e-16 60.8 1.3 2.9 4 0 0 4 4 4 1 PLAC8 family PrsW-protease PF13367.1 EWM22752.1 - 3.7e-15 55.6 8.0 3.7e-15 55.6 5.6 2.9 3 0 0 3 3 3 1 Protease prsW family DUF1769 PF08588.5 EWM22754.1 - 0.013 15.4 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) KH_1 PF00013.24 EWM22755.1 - 3.8e-19 68.0 0.2 6e-09 35.4 0.1 2.3 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 EWM22755.1 - 3.6e-11 42.4 2.6 4.5e-05 22.9 0.0 2.6 2 0 0 2 2 2 2 KH domain KH_2 PF07650.12 EWM22755.1 - 6.5e-07 28.8 1.0 0.021 14.3 0.1 2.3 2 0 0 2 2 2 2 KH domain Clat_adaptor_s PF01217.15 EWM22756.1 - 1.2e-23 83.3 0.1 1.5e-23 83.0 0.1 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Transp_cyt_pur PF02133.10 EWM22759.1 - 1.2e-17 63.6 18.0 1.5e-17 63.3 12.5 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin FixQ PF05545.6 EWM22759.1 - 0.42 10.2 2.4 3.1 7.5 0.2 3.1 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Methyltrans_RNA PF04452.9 EWM22762.1 - 3e-26 91.9 0.0 1.8e-25 89.3 0.0 1.9 1 1 0 1 1 1 1 RNA methyltransferase PHO4 PF01384.15 EWM22763.1 - 0.34 9.5 6.4 1.2 7.7 4.4 1.7 1 1 0 1 1 1 0 Phosphate transporter family KTI12 PF08433.5 EWM22764.1 - 1.9e-23 83.0 0.0 2.2e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 SusD-like_3 PF14322.1 EWM22764.1 - 0.14 12.2 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Starch-binding associating with outer membrane Mito_carr PF00153.22 EWM22765.1 - 2.3e-53 177.8 2.1 1.1e-18 66.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1350 PF07082.6 EWM22766.1 - 5.9e-31 107.4 0.0 2.9e-23 82.2 0.0 2.8 2 2 0 2 2 2 2 Protein of unknown function (DUF1350) Abhydrolase_5 PF12695.2 EWM22766.1 - 1.7e-05 24.6 0.1 4.9e-05 23.1 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Rad10 PF03834.9 EWM22768.1 - 4.9e-08 32.5 0.0 7.2e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Rad10 PF03834.9 EWM22769.1 - 7.3e-23 80.0 0.1 9.6e-23 79.6 0.1 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Got1 PF04178.7 EWM22772.1 - 1.5e-24 86.3 13.4 2.1e-24 85.9 9.3 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family SUR7 PF06687.7 EWM22772.1 - 0.1 12.1 3.9 0.17 11.4 2.7 1.3 1 0 0 1 1 1 0 SUR7/PalI family Herpes_LMP1 PF05297.6 EWM22772.1 - 2.2 7.1 9.0 3.4 6.4 6.2 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) EVC2_like PF12297.3 EWM22772.1 - 9.9 4.6 6.6 1.5 7.4 1.1 1.8 1 1 0 2 2 2 0 Ellis van Creveld protein 2 like protein PI3_PI4_kinase PF00454.22 EWM22773.1 - 8.9e-42 143.1 0.0 1.9e-41 142.0 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EWM22773.1 - 0.00026 20.3 0.0 0.0007 18.9 0.0 1.8 1 0 0 1 1 1 1 FATC domain TPR_7 PF13176.1 EWM22773.1 - 0.0041 16.8 0.3 0.032 14.0 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EWM22773.1 - 0.013 15.4 0.2 1.1 9.2 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EWM22773.1 - 0.066 13.1 2.8 0.074 13.0 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Cation_ATPase_C PF00689.16 EWM22774.1 - 7.4e-40 136.4 3.1 1.2e-39 135.6 2.2 1.4 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EWM22774.1 - 1.4e-22 81.2 0.0 7.4e-16 59.2 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EWM22774.1 - 5.8e-17 61.4 0.0 1.1e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EWM22774.1 - 2.2e-14 54.0 0.0 5.3e-14 52.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EWM22774.1 - 0.00033 20.3 1.3 0.044 13.3 0.5 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase NUC194 PF08163.7 EWM22775.1 - 0.0006 18.7 0.0 1.2 7.8 0.0 3.0 2 1 0 2 2 2 2 NUC194 domain RNase_Zc3h12a PF11977.3 EWM22776.1 - 1.9e-16 60.2 0.0 2.5e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain GTP1_OBG PF01018.17 EWM22776.1 - 0.054 13.1 0.1 0.084 12.5 0.1 1.2 1 0 0 1 1 1 0 GTP1/OBG SAC3_GANP PF03399.11 EWM22777.1 - 0.0031 17.0 0.0 0.005 16.4 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family NMT1 PF09084.6 EWM22780.1 - 6.4e-11 42.2 0.0 7.9e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like THF_DHG_CYH PF00763.18 EWM22781.1 - 8e-07 29.1 0.0 1.1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain DUF3350 PF11830.3 EWM22782.1 - 0.079 12.9 0.2 0.2 11.6 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3350) DUF2798 PF11391.3 EWM22784.1 - 0.0037 16.9 0.1 0.0066 16.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2798) ATG16 PF08614.6 EWM22784.1 - 2.6 7.8 14.8 12 5.6 0.1 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF2894 PF11445.3 EWM22784.1 - 9.4 6.4 19.7 1.1 9.4 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) Pkinase PF00069.20 EWM22786.1 - 2.6e-63 213.6 0.0 3.7e-63 213.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM22786.1 - 3.2e-28 98.4 0.0 4.7e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EWM22786.1 - 1e-05 24.7 0.0 0.00017 20.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like SynMuv_product PF06047.6 EWM22787.1 - 7.4e-32 109.2 2.2 9.8e-32 108.8 1.5 1.1 1 0 0 1 1 1 1 Ras-induced vulval development antagonist DTW PF03942.10 EWM22787.1 - 0.044 12.9 0.4 0.052 12.7 0.3 1.0 1 0 0 1 1 1 0 DTW domain RNase_PH PF01138.16 EWM22788.1 - 3e-27 95.5 0.0 7.9e-27 94.1 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Lactate_perm PF02652.9 EWM22788.1 - 0.3 9.5 1.0 0.41 9.0 0.7 1.1 1 0 0 1 1 1 0 L-lactate permease RNase_PH PF01138.16 EWM22789.1 - 2.3e-30 105.5 0.0 6.1e-30 104.2 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Lactate_perm PF02652.9 EWM22789.1 - 0.31 9.5 1.0 0.41 9.0 0.7 1.1 1 0 0 1 1 1 0 L-lactate permease Rhodanese PF00581.15 EWM22794.1 - 2.8e-13 50.2 0.0 3.5e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Septin PF00735.13 EWM22796.1 - 5.4e-14 51.8 0.0 6.7e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Septin FAM165 PF14981.1 EWM22796.1 - 0.74 9.3 3.4 1.5 8.4 2.3 1.4 1 0 0 1 1 1 0 FAM165 family Septin PF00735.13 EWM22797.1 - 0.0014 17.6 0.0 0.0018 17.3 0.0 1.0 1 0 0 1 1 1 1 Septin Nrf1_DNA-bind PF10491.4 EWM22798.1 - 0.029 13.5 0.2 0.045 12.9 0.1 1.2 1 0 0 1 1 1 0 NLS-binding and DNA-binding and dimerisation domains of Nrf1 Methyltransf_21 PF05050.7 EWM22800.1 - 9.7e-06 25.6 0.0 1.3e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_22 PF13383.1 EWM22800.1 - 1.2e-05 24.9 0.1 1.8e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain TylF PF05711.6 EWM22801.1 - 7.3e-72 241.4 0.0 8.9e-72 241.1 0.0 1.0 1 0 0 1 1 1 1 Macrocin-O-methyltransferase (TylF) Methyltransf_24 PF13578.1 EWM22801.1 - 1.4e-07 32.3 0.0 2.3e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 EWM22801.1 - 0.00054 19.3 0.1 0.058 12.6 0.0 2.2 2 0 0 2 2 2 2 Cephalosporin hydroxylase Exo_endo_phos PF03372.18 EWM22803.1 - 3e-07 30.6 0.1 8e-06 25.9 0.0 2.3 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos PF03372.18 EWM22804.1 - 2.7e-07 30.8 0.1 7.5e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family ABC_transp_aux PF09822.4 EWM22806.1 - 0.0015 18.0 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 ABC-type uncharacterized transport system TrfA PF07042.6 EWM22808.1 - 0.028 13.2 0.0 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 TrfA protein Fer2_BFD PF04324.10 EWM22809.1 - 0.099 12.7 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 BFD-like [2Fe-2S] binding domain DUF605 PF04652.11 EWM22809.1 - 0.71 9.2 8.5 2.4 7.4 4.8 1.9 2 0 0 2 2 2 0 Vta1 like GTP_CH_N PF12471.3 EWM22810.1 - 1.5e-81 272.7 0.1 2.4e-81 272.0 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 EWM22810.1 - 3e-15 55.8 0.0 4.8e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Pribosyltran_N PF13793.1 EWM22811.1 - 3.2e-39 133.2 0.0 5.2e-38 129.3 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EWM22811.1 - 7e-19 68.2 0.2 2.3e-18 66.6 0.0 1.9 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EWM22811.1 - 5.5e-09 35.8 0.7 2.1e-08 33.9 0.1 2.3 3 0 0 3 3 3 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EWM22811.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase TBCC PF07986.7 EWM22811.1 - 0.15 11.4 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 Tubulin binding cofactor C Ceramidase PF05875.7 EWM22813.1 - 3.1e-15 56.0 0.9 5.8e-15 55.1 0.6 1.4 1 0 0 1 1 1 1 Ceramidase Ank PF00023.25 EWM22814.1 - 1.6e-36 122.3 0.0 1.1e-10 40.7 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_2 PF12796.2 EWM22814.1 - 5.9e-36 122.6 0.8 1.4e-18 66.9 0.4 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EWM22814.1 - 3.2e-34 116.7 0.6 2.4e-13 50.1 0.1 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EWM22814.1 - 5.1e-26 90.1 4.8 2.5e-12 46.5 0.4 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM22814.1 - 1.1e-23 80.9 0.0 4.1e-06 26.5 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat PPR_2 PF13041.1 EWM22814.1 - 0.062 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 PPR repeat family PPR PF01535.15 EWM22814.1 - 0.097 12.6 0.1 0.26 11.3 0.1 1.7 1 0 0 1 1 1 0 PPR repeat SDA1 PF05285.7 EWM22817.1 - 2.1e-10 40.3 57.7 8.3e-10 38.4 40.0 1.9 1 1 0 1 1 1 1 SDA1 Polyketide_cyc PF03364.15 EWM22819.1 - 3.5e-08 33.5 0.1 6.7e-08 32.5 0.1 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 EWM22819.1 - 0.00022 21.4 0.0 0.0034 17.5 0.0 2.2 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF220 PF02713.9 EWM22819.1 - 0.16 11.6 0.0 0.44 10.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF220 COXG PF06240.8 EWM22819.1 - 0.17 11.5 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit G (CoxG) DEC-1_N PF04625.8 EWM22819.1 - 0.73 8.4 3.0 2.5 6.7 0.1 2.1 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region DUF2512 PF10710.4 EWM22821.1 - 0.42 10.0 5.7 0.7 9.3 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2512) VIT1 PF01988.14 EWM22821.1 - 6.6 6.1 6.3 11 5.3 4.4 1.3 1 0 0 1 1 1 0 VIT family Amino_oxidase PF01593.19 EWM22822.1 - 2.4e-41 142.2 4.6 8e-28 97.6 0.3 2.2 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EWM22822.1 - 6.2e-11 42.1 0.4 1.4e-10 41.0 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EWM22822.1 - 4.1e-06 25.9 0.3 6e-06 25.3 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EWM22822.1 - 9.6e-06 25.7 0.3 1.5e-05 25.2 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EWM22822.1 - 8e-05 22.6 0.1 0.00011 22.1 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EWM22822.1 - 9.3e-05 21.4 0.3 0.00013 21.0 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EWM22822.1 - 0.0013 17.8 0.4 0.0025 16.9 0.3 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EWM22822.1 - 0.005 15.3 0.3 0.0073 14.8 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 EWM22822.1 - 0.015 14.2 0.2 0.022 13.7 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 EWM22822.1 - 0.061 12.1 0.7 0.092 11.5 0.5 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A TrkA_N PF02254.13 EWM22822.1 - 0.098 12.6 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Malic_M PF03949.10 EWM22822.1 - 0.12 11.8 0.6 1.3 8.5 0.2 2.0 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain HAD_2 PF13419.1 EWM22825.1 - 1.5e-21 77.3 0.0 1.9e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EWM22825.1 - 4.2e-16 60.0 0.1 9.3e-16 58.8 0.1 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EWM22825.1 - 3.4e-08 33.0 0.0 7.3e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EWM22825.1 - 0.0011 19.2 0.0 0.0027 17.9 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EWM22825.1 - 0.056 13.3 0.0 7.1 6.5 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 EWM22825.1 - 0.12 11.9 0.0 12 5.4 0.0 2.3 2 0 0 2 2 2 0 Acid Phosphatase DUF566 PF04484.7 EWM22826.1 - 2.9 7.3 9.9 4.2 6.7 6.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF605 PF04652.11 EWM22826.1 - 5.9 6.1 8.9 7.4 5.8 6.2 1.1 1 0 0 1 1 1 0 Vta1 like FANCL_C PF11793.3 EWM22827.1 - 1.7e-19 69.5 1.8 3.5e-19 68.5 1.2 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain WD-3 PF09765.4 EWM22827.1 - 3.5e-10 39.6 0.0 6.6e-10 38.7 0.0 1.4 2 0 0 2 2 2 1 WD-repeat region zf-RING_2 PF13639.1 EWM22827.1 - 0.001 18.8 8.4 0.003 17.3 5.8 1.8 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EWM22827.1 - 0.0062 16.6 3.9 0.017 15.2 2.7 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-HC5HC2H PF13771.1 EWM22827.1 - 0.012 15.7 1.9 0.017 15.2 1.3 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain Cys_rich_CPXG PF14255.1 EWM22827.1 - 0.046 13.5 5.2 0.14 12.0 0.1 2.3 2 0 0 2 2 2 0 Cysteine-rich CPXCG zf-Apc11 PF12861.2 EWM22827.1 - 0.074 12.8 3.8 0.35 10.7 2.4 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H_2 PF13832.1 EWM22827.1 - 0.74 9.8 3.7 1.7 8.6 2.5 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain PHD PF00628.24 EWM22827.1 - 5 6.8 7.2 0.31 10.7 1.4 1.6 2 0 0 2 2 2 0 PHD-finger ArfGap PF01412.13 EWM22828.1 - 0.001 18.8 0.1 0.001 18.8 0.0 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Hid1 PF12722.2 EWM22828.1 - 5.6 4.5 6.6 6.9 4.2 4.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAP PF02037.22 EWM22830.1 - 3.6e-09 35.8 0.2 8.6e-09 34.6 0.1 1.7 1 0 0 1 1 1 1 SAP domain RAP PF08373.5 EWM22830.1 - 4e-06 26.5 0.1 1.8e-05 24.4 0.1 2.1 1 1 0 1 1 1 1 RAP domain HTH_31 PF13560.1 EWM22830.1 - 0.016 15.4 0.7 0.13 12.4 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HeH PF12949.2 EWM22830.1 - 0.039 13.5 0.1 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 HeH/LEM domain KH_1 PF00013.24 EWM22832.1 - 7.8e-29 99.1 0.0 2.8e-08 33.2 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EWM22832.1 - 5e-18 64.3 0.5 1.4e-05 24.6 0.0 3.9 4 0 0 4 4 4 3 KH domain KH_2 PF07650.12 EWM22832.1 - 2.5e-07 30.1 0.1 0.41 10.2 0.0 3.5 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EWM22832.1 - 0.0064 16.2 0.2 3.9 7.3 0.0 3.3 3 0 0 3 3 3 1 NusA-like KH domain KH_4 PF13083.1 EWM22832.1 - 0.0077 15.8 5.3 0.13 11.9 0.0 3.0 3 0 0 3 3 3 2 KH domain Ycf1 PF05758.7 EWM22832.1 - 1.1 6.8 4.6 1.2 6.8 3.2 1.1 1 0 0 1 1 1 0 Ycf1 DUF2890 PF11081.3 EWM22832.1 - 5.2 7.0 16.9 7.8 6.5 11.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DIOX_N PF14226.1 EWM22833.1 - 7.8e-13 48.9 0.1 3.2e-07 30.8 0.0 3.7 3 1 1 4 4 4 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EWM22833.1 - 9.6e-10 38.6 0.0 1.1e-06 28.8 0.0 2.4 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily Zn_clus PF00172.13 EWM22836.1 - 6.7e-05 22.7 9.8 0.00011 21.9 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.2 EWM22837.1 - 4.9e-25 87.6 0.6 3.1e-17 62.6 0.1 2.3 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EWM22837.1 - 1.3e-23 81.5 4.7 1.7e-11 43.3 0.1 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 EWM22837.1 - 1.3e-17 63.8 0.1 1.1e-05 25.7 0.0 4.1 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EWM22837.1 - 3.6e-15 55.6 2.1 5.5e-09 35.9 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM22837.1 - 3.6e-15 54.5 0.7 1e-05 25.2 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat DUF218 PF02698.12 EWM22838.1 - 9e-08 31.7 0.0 1.6e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain Claudin_2 PF13903.1 EWM22840.1 - 0.0099 15.5 7.4 0.032 13.9 5.2 1.8 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction NUDIX PF00293.23 EWM22841.1 - 1.1e-16 60.7 0.0 1.8e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Imm45 PF15603.1 EWM22841.1 - 0.15 12.2 0.0 1.3 9.2 0.0 2.1 2 0 0 2 2 2 0 Immunity protein 45 TPR_11 PF13414.1 EWM22842.1 - 1.6e-07 30.8 9.7 9.8e-05 21.9 0.2 3.3 1 1 2 3 3 3 2 TPR repeat TPR_12 PF13424.1 EWM22842.1 - 8.2e-06 25.6 14.5 0.00094 19.0 3.1 4.0 2 1 3 5 5 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 EWM22842.1 - 0.00016 21.9 2.8 0.00016 21.9 1.9 3.2 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EWM22842.1 - 0.0002 21.9 12.7 0.00042 20.8 3.5 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EWM22842.1 - 0.00032 20.4 17.8 0.02 14.7 0.5 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 EWM22842.1 - 0.00046 20.0 8.4 0.0064 16.3 0.2 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EWM22842.1 - 0.0025 17.4 9.7 1.6 8.7 0.2 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EWM22842.1 - 0.0042 17.5 13.1 0.41 11.4 0.3 4.9 2 1 3 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 EWM22842.1 - 0.0048 17.0 5.7 0.71 10.2 0.1 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat Golgin_A5 PF09787.4 EWM22842.1 - 0.028 12.9 1.6 0.038 12.5 1.1 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Plectin PF00681.15 EWM22842.1 - 0.046 13.2 0.3 1 8.9 0.0 2.9 3 0 0 3 3 3 0 Plectin repeat TPR_21 PF09976.4 EWM22842.1 - 0.068 13.1 2.0 0.1 12.5 0.5 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Macoilin PF09726.4 EWM22842.1 - 0.11 10.8 0.7 0.13 10.5 0.5 1.1 1 0 0 1 1 1 0 Transmembrane protein TPR_20 PF14561.1 EWM22842.1 - 0.21 11.7 2.4 1.9 8.6 0.8 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EWM22842.1 - 0.29 10.8 13.1 2.3 7.9 0.2 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 EWM22842.1 - 0.69 10.5 6.8 2.7 8.6 0.2 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat DUF2638 PF10937.3 EWM22842.1 - 5.1 8.1 8.0 5.1 8.1 4.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2638) Suppressor_APC PF11414.3 EWM22843.1 - 0.86 9.4 3.6 2.2 8.0 0.7 2.2 1 1 1 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein CwfJ_C_2 PF04676.9 EWM22844.1 - 0.00063 20.1 0.0 0.00088 19.7 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 RRM_1 PF00076.17 EWM22847.1 - 4.2e-27 93.5 0.0 1.2e-15 56.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM22847.1 - 1.9e-19 69.3 0.0 3.2e-12 46.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM22847.1 - 1.3e-08 34.5 0.0 2.7e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EWM22848.1 - 3.9e-09 36.0 0.0 5.7e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM22848.1 - 9.1e-05 22.3 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Peptidase_M17 PF00883.16 EWM22849.1 - 2.1e-50 171.3 0.0 3.3e-50 170.7 0.0 1.3 1 1 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Apc3 PF12895.2 EWM22850.1 - 6.9e-12 45.3 0.3 9.3e-12 44.9 0.2 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 EWM22850.1 - 0.00072 19.7 5.4 0.11 12.9 0.6 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EWM22850.1 - 0.01 16.5 1.2 1.3 9.8 0.4 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EWM22850.1 - 0.026 15.1 3.9 0.84 10.4 0.9 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EWM22850.1 - 0.075 13.3 0.5 0.63 10.4 0.5 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Vps53_N PF04100.7 EWM22853.1 - 4e-94 315.5 0.4 1.5e-82 277.4 0.5 2.1 2 0 0 2 2 2 2 Vps53-like, N-terminal Sec6 PF06046.8 EWM22853.1 - 1.2e-09 36.8 0.0 2.8e-08 32.3 0.0 2.5 3 0 0 3 3 3 1 Exocyst complex component Sec6 DUF2450 PF10475.4 EWM22853.1 - 5.4e-09 35.3 3.0 1e-08 34.4 2.1 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Baculo_PEP_C PF04513.7 EWM22853.1 - 0.77 9.5 6.4 2.3 8.0 1.0 2.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.1 EWM22853.1 - 3.1 6.1 7.0 1.8 6.9 1.4 1.9 1 1 1 2 2 2 0 AAA domain MCPsignal PF00015.16 EWM22853.1 - 3.7 7.0 11.4 0.32 10.4 1.9 2.6 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Pkinase PF00069.20 EWM22854.1 - 1.9e-65 220.6 0.0 3e-65 219.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM22854.1 - 2.6e-29 102.0 0.0 2.8e-28 98.7 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 EWM22854.1 - 0.00012 22.2 0.0 0.00034 20.7 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_3 PF14593.1 EWM22854.1 - 0.044 13.6 0.0 0.09 12.6 0.0 1.5 1 0 0 1 1 1 0 PH domain Pox_ser-thr_kin PF05445.6 EWM22854.1 - 0.11 11.3 1.6 0.26 10.0 0.4 1.9 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase APH PF01636.18 EWM22854.1 - 4.2 7.0 6.9 0.66 9.6 0.0 3.0 3 1 0 3 3 3 0 Phosphotransferase enzyme family TPR_1 PF00515.23 EWM22855.1 - 5.2e-37 123.9 7.6 2.5e-08 33.1 0.4 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 EWM22855.1 - 7.2e-36 119.2 10.9 6.7e-06 25.6 0.4 7.4 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 EWM22855.1 - 1.4e-35 120.7 10.5 1.4e-12 47.0 1.9 5.2 3 2 1 5 5 5 4 TPR repeat TPR_16 PF13432.1 EWM22855.1 - 6.6e-26 90.3 12.5 1.2e-08 35.3 0.1 5.2 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_17 PF13431.1 EWM22855.1 - 3.7e-23 79.7 4.7 0.00058 19.8 0.1 7.0 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 EWM22855.1 - 4.7e-22 77.7 26.7 5.9e-07 29.3 0.1 5.6 2 1 5 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.1 EWM22855.1 - 5.8e-22 75.7 1.1 0.00099 18.7 0.0 7.1 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 EWM22855.1 - 5.4e-19 66.9 14.1 0.001 19.5 0.2 7.9 1 1 7 8 8 8 7 Tetratricopeptide repeat TPR_19 PF14559.1 EWM22855.1 - 8.6e-18 64.4 7.8 1.5e-10 41.2 0.6 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EWM22855.1 - 1.5e-16 60.3 9.6 1.2e-05 25.3 0.1 4.3 1 1 3 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EWM22855.1 - 7.7e-13 47.1 9.6 0.019 14.7 0.0 6.9 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_6 PF13174.1 EWM22855.1 - 3.6e-11 42.7 5.6 1.1 9.8 0.1 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 EWM22855.1 - 4.3e-11 42.5 12.9 6.2e-07 29.1 1.7 4.4 4 2 0 4 4 4 2 Tetratricopeptide repeat FAT PF02259.18 EWM22855.1 - 2.1e-07 30.2 0.1 0.00018 20.6 0.0 2.3 1 1 1 2 2 2 2 FAT domain TPR_10 PF13374.1 EWM22855.1 - 5.4e-07 29.3 9.6 0.18 11.7 0.0 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat NARP1 PF12569.3 EWM22855.1 - 8.6e-07 28.0 0.3 0.021 13.5 0.1 2.8 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_4 PF07721.9 EWM22855.1 - 5.5e-05 23.2 0.2 1.1 9.8 0.1 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 EWM22855.1 - 5.9e-05 22.2 5.8 0.0025 16.9 0.4 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.1 EWM22855.1 - 0.00023 21.2 2.5 0.01 15.9 0.8 3.2 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_21 PF09976.4 EWM22855.1 - 0.00036 20.4 1.2 0.04 13.8 0.2 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat ChAPs PF09295.5 EWM22855.1 - 0.0015 17.3 0.1 0.1 11.3 0.0 2.5 1 1 2 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) Vg_Tdu PF07545.9 EWM22855.1 - 0.2 11.1 0.7 1.8 8.0 0.2 2.4 1 1 1 2 2 2 0 Vestigial/Tondu family CLN3 PF02487.12 EWM22856.1 - 2.3e-63 214.3 13.8 4.3e-32 111.3 0.0 3.0 2 1 1 3 3 3 3 CLN3 protein MFS_1 PF07690.11 EWM22856.1 - 6.4e-05 21.8 25.0 9.1e-05 21.3 4.1 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily CLN3 PF02487.12 EWM22857.1 - 1e-62 212.2 14.3 1.4e-31 109.6 0.0 3.0 2 1 1 3 3 3 3 CLN3 protein MFS_1 PF07690.11 EWM22857.1 - 6.3e-05 21.8 25.2 0.00012 20.9 4.5 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily CLN3 PF02487.12 EWM22858.1 - 1e-53 182.6 1.8 3e-32 111.8 0.0 2.0 2 0 0 2 2 2 2 CLN3 protein MFS_1 PF07690.11 EWM22858.1 - 0.00012 20.9 6.7 0.00012 20.9 4.6 2.6 1 1 1 2 2 2 1 Major Facilitator Superfamily RRM_1 PF00076.17 EWM22861.1 - 9.7e-34 114.8 0.0 1.8e-16 59.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM22861.1 - 1.9e-28 98.2 0.0 7.9e-13 48.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM22861.1 - 3.5e-07 29.9 0.0 0.0041 16.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EWM22861.1 - 0.0014 18.3 0.0 0.46 10.2 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Abhydrolase_6 PF12697.2 EWM22862.1 - 1.8e-13 50.9 2.8 3.3e-13 50.0 2.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM22862.1 - 0.0048 16.6 0.0 0.0065 16.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Imp-YgjV PF10688.4 EWM22863.1 - 0.025 14.0 0.1 0.03 13.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial inner membrane protein Cation_ATPase_N PF00690.21 EWM22863.1 - 0.056 12.9 0.1 2.5 7.6 0.0 2.1 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus MORN PF02493.15 EWM22865.1 - 4.1e-28 95.3 30.3 2e-07 30.3 0.0 6.3 6 0 0 6 6 6 5 MORN repeat SAM_2 PF07647.12 EWM22865.1 - 0.0019 18.0 2.3 0.1 12.4 0.0 2.4 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EWM22865.1 - 0.028 14.5 1.1 3.7 7.8 0.0 2.5 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Pkinase PF00069.20 EWM22866.1 - 1.3e-49 168.6 0.0 1.8e-49 168.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM22866.1 - 2.1e-17 63.0 0.0 3.5e-17 62.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EWM22866.1 - 0.012 14.6 0.1 0.02 13.9 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EWM22866.1 - 0.033 13.9 1.2 0.056 13.1 0.2 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Clathrin PF00637.15 EWM22867.1 - 4.5e-08 32.7 3.8 0.015 14.9 0.1 4.2 4 0 0 4 4 4 2 Region in Clathrin and VPS Chromosome_seg PF13889.1 EWM22867.1 - 0.00043 20.1 0.0 0.00098 18.9 0.0 1.5 1 0 0 1 1 1 1 Chromosome segregation during meiosis TPR_12 PF13424.1 EWM22867.1 - 0.00049 19.9 25.7 0.084 12.8 0.1 6.6 4 2 2 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 EWM22867.1 - 0.0011 18.6 3.9 0.0011 18.6 2.7 5.4 3 1 1 4 4 4 1 TPR repeat TPR_2 PF07719.12 EWM22867.1 - 0.0011 18.7 28.5 0.17 11.8 0.2 7.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.23 EWM22867.1 - 0.0022 17.5 8.0 2 8.1 0.0 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EWM22867.1 - 0.0023 18.0 0.2 0.0023 18.0 0.2 4.1 2 2 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EWM22867.1 - 0.081 12.7 3.9 13 5.8 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EWM22867.1 - 1.5 9.7 20.7 1.4 9.7 0.1 6.0 3 3 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EWM22867.1 - 1.6 8.7 13.7 8.2 6.4 0.1 5.6 3 2 3 6 6 6 0 Tetratricopeptide repeat CTP_transf_1 PF01148.15 EWM22868.1 - 0.00021 21.0 5.4 0.1 12.2 0.0 2.4 2 1 0 2 2 2 2 Cytidylyltransferase family MFS_1 PF07690.11 EWM22869.1 - 0.00064 18.5 9.1 0.00078 18.2 6.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Bax1-I PF01027.15 EWM22869.1 - 0.13 11.8 4.9 0.16 11.5 3.4 1.0 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Rubi_NSP_C PF12601.3 EWM22869.1 - 0.47 10.3 2.0 0.59 10.0 0.2 2.1 2 1 0 2 2 2 0 Rubivirus non-structural protein CLPTM1 PF05602.7 EWM22870.1 - 0.017 13.8 0.0 0.019 13.7 0.0 1.0 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) BACK PF07707.10 EWM22873.1 - 3.4e-07 30.0 0.3 4.6e-05 23.2 0.1 2.1 2 0 0 2 2 2 2 BTB And C-terminal Kelch BTB PF00651.26 EWM22873.1 - 0.00021 21.2 0.1 0.24 11.3 0.0 2.2 1 1 1 2 2 2 2 BTB/POZ domain WW PF00397.21 EWM22876.1 - 0.00034 20.3 5.5 0.0012 18.6 3.8 2.0 1 0 0 1 1 1 1 WW domain Pol_alpha_B_N PF08418.5 EWM22876.1 - 0.085 12.3 7.0 0.15 11.5 4.9 1.5 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal WW PF00397.21 EWM22877.1 - 0.00094 18.9 5.5 0.00094 18.9 3.8 2.1 2 0 0 2 2 2 1 WW domain Pol_alpha_B_N PF08418.5 EWM22877.1 - 0.96 8.9 10.8 1.9 7.9 7.5 1.6 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Peptidase_C65 PF10275.4 EWM22878.1 - 5.7e-55 186.3 0.0 2.7e-54 184.0 0.0 1.8 1 1 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.14 EWM22878.1 - 0.0044 17.5 0.0 2.6 8.6 0.0 2.5 2 0 0 2 2 2 2 OTU-like cysteine protease Peptidase_C65 PF10275.4 EWM22879.1 - 5.7e-55 186.3 0.0 2.7e-54 184.0 0.0 1.8 1 1 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.14 EWM22879.1 - 0.0044 17.5 0.0 2.6 8.6 0.0 2.5 2 0 0 2 2 2 2 OTU-like cysteine protease AAA PF00004.24 EWM22880.1 - 7e-09 35.9 0.1 3.5e-08 33.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 EWM22881.1 - 2.5e-31 108.4 0.0 3.2e-30 104.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EWM22881.1 - 3.4e-17 62.0 0.0 7.2e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EWM22881.1 - 8.2e-06 25.7 0.0 2.2e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EWM22881.1 - 0.035 14.2 0.1 0.39 10.8 0.1 2.4 1 1 0 1 1 1 0 AAA domain UCH PF00443.24 EWM22884.1 - 1.6e-22 79.8 0.0 1.8e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EWM22884.1 - 6.5e-08 32.3 0.0 9.6e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Sporozoite_P67 PF05642.6 EWM22884.1 - 9.1 3.9 21.9 14 3.3 15.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Vps51 PF08700.6 EWM22886.1 - 1e-08 34.8 0.1 3.5e-08 33.1 0.1 1.9 1 0 0 1 1 1 1 Vps51/Vps67 UPF0261 PF06792.6 EWM22886.1 - 0.19 10.1 0.0 0.31 9.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) DNA_RNApol_7kD PF03604.8 EWM22887.1 - 3.3e-15 55.2 5.8 7.7e-15 54.0 4.0 1.7 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit A2L_zn_ribbon PF08792.5 EWM22887.1 - 0.18 11.2 3.7 0.55 9.7 2.5 1.9 1 1 0 1 1 1 0 A2L zinc ribbon domain DZR PF12773.2 EWM22887.1 - 0.18 11.6 3.8 0.35 10.7 2.6 1.5 1 0 0 1 1 1 0 Double zinc ribbon HypA PF01155.14 EWM22887.1 - 0.39 10.3 3.3 0.47 10.1 1.4 1.9 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family NCD3G PF07562.9 EWM22887.1 - 1.5 8.5 6.7 0.24 11.1 0.7 2.4 2 1 1 3 3 3 0 Nine Cysteines Domain of family 3 GPCR bZIP_1 PF00170.16 EWM22888.1 - 0.00016 21.5 9.3 0.00033 20.5 6.4 1.5 1 0 0 1 1 1 1 bZIP transcription factor Helicase_C_3 PF13625.1 EWM22889.1 - 3.6e-23 81.7 0.0 8.1e-23 80.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EWM22889.1 - 2.5e-14 53.5 0.0 4.1e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EWM22889.1 - 2.3e-10 39.7 0.0 3.4e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EWM22889.1 - 1.3e-09 37.7 0.1 3.6e-09 36.3 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PPR_2 PF13041.1 EWM22890.1 - 1.2e-90 297.3 1.7 1.6e-11 43.9 0.0 18.7 10 6 9 20 20 20 13 PPR repeat family PPR_3 PF13812.1 EWM22890.1 - 2.2e-60 195.9 40.2 8e-06 25.7 0.0 20.5 24 0 0 24 24 24 13 Pentatricopeptide repeat domain PPR PF01535.15 EWM22890.1 - 2.2e-59 193.4 36.2 3.4e-06 26.6 0.0 21.7 23 0 0 23 23 23 10 PPR repeat PPR_1 PF12854.2 EWM22890.1 - 4.2e-38 128.5 7.1 1.8e-05 24.1 0.0 14.1 14 0 0 14 14 14 7 PPR repeat ECSIT PF06239.6 EWM22890.1 - 0.0016 17.3 0.0 4.7 6.0 0.0 4.5 5 0 0 5 5 5 1 Evolutionarily conserved signalling intermediate in Toll pathway MRP-S27 PF10037.4 EWM22890.1 - 0.018 13.9 0.0 0.27 10.1 0.0 2.7 4 0 0 4 4 4 0 Mitochondrial 28S ribosomal protein S27 Gp37 PF09646.5 EWM22890.1 - 0.052 12.9 0.0 0.16 11.4 0.0 1.8 1 0 0 1 1 1 0 Gp37 protein TPR_14 PF13428.1 EWM22890.1 - 0.18 12.5 24.6 1.8 9.3 0.0 9.1 7 2 2 9 9 9 0 Tetratricopeptide repeat Radical_SAM PF04055.16 EWM22891.1 - 4.4e-17 62.7 0.0 7e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.15 EWM22891.1 - 2.6e-16 59.2 0.0 5.2e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Sugar_tr PF00083.19 EWM22892.1 - 2.5e-121 405.4 24.0 2.9e-121 405.2 16.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EWM22892.1 - 1.2e-32 113.0 27.4 1.2e-32 113.0 19.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EWM22892.1 - 0.0021 16.3 1.3 0.0036 15.5 0.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TruB_C PF09142.6 EWM22893.1 - 0.14 11.7 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal UPF0300 PF08594.5 EWM22894.1 - 0.057 12.3 0.1 6.2 5.6 0.0 2.1 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0300) NUDIX PF00293.23 EWM22895.1 - 4.8e-17 61.8 0.0 9.5e-17 60.9 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Sugar_tr PF00083.19 EWM22896.1 - 1.6e-18 66.5 3.0 2.7e-18 65.7 2.1 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EWM22896.1 - 4.5e-07 28.9 16.7 1.2e-06 27.5 11.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Ubiq_cyt_C_chap PF03981.7 EWM22898.1 - 6.4e-05 22.8 0.1 9.8e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone WW PF00397.21 EWM22899.1 - 8.5e-09 35.1 1.5 1.6e-08 34.2 1.0 1.5 1 0 0 1 1 1 1 WW domain AF1Q PF15017.1 EWM22899.1 - 0.95 9.4 3.7 1.2 9.0 2.6 1.1 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator HGTP_anticodon PF03129.15 EWM22912.1 - 0.078 12.9 0.3 0.12 12.2 0.2 1.3 1 0 0 1 1 1 0 Anticodon binding domain YscJ_FliF_C PF08345.6 EWM22912.1 - 0.47 10.4 15.8 0.067 13.1 7.8 1.8 1 1 1 2 2 2 0 Flagellar M-ring protein C-terminal Kinesin PF00225.18 EWM22915.1 - 1.7e-96 322.8 0.0 2.2e-96 322.5 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Dus PF01207.12 EWM22921.1 - 1.9e-17 63.0 0.0 2.4e-17 62.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DUF3333 PF11812.3 EWM22922.1 - 0.081 12.9 0.4 0.11 12.5 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3333) Mito_fiss_reg PF05308.6 EWM22923.1 - 0.24 10.7 5.0 0.25 10.6 3.4 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator SOUL PF04832.7 EWM22925.1 - 1.2e-13 51.0 0.0 1.3e-13 50.8 0.0 1.0 1 0 0 1 1 1 1 SOUL heme-binding protein PP-binding PF00550.20 EWM22928.1 - 0.0096 16.1 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site Phage_int_SAM_1 PF02899.12 EWM22929.1 - 0.00095 19.2 0.1 0.0014 18.7 0.1 1.2 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain DUF3486 PF11985.3 EWM22929.1 - 0.0028 17.7 0.3 0.0036 17.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3486) Phage_int_SAM_4 PF13495.1 EWM22929.1 - 0.046 14.0 0.0 0.063 13.6 0.0 1.2 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain XH PF03469.9 EWM22930.1 - 1.2e-08 34.6 0.0 2.4e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 XH domain DUF3774 PF12609.3 EWM22930.1 - 0.59 11.0 3.5 3.2 8.6 0.2 2.6 2 0 0 2 2 2 0 Wound-induced protein FA_hydroxylase PF04116.8 EWM22932.1 - 1.2e-12 48.2 17.0 1.2e-12 48.2 11.8 2.2 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily DUF4168 PF13767.1 EWM22934.1 - 6.8e-17 61.8 0.0 2.7e-07 31.1 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4168) Iso_dh PF00180.15 EWM22938.1 - 1.5e-125 418.8 0.0 1.7e-125 418.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PPR_3 PF13812.1 EWM22939.1 - 4.9e-09 35.7 2.7 0.032 14.4 0.0 5.2 5 0 0 5 5 5 1 Pentatricopeptide repeat domain PPR PF01535.15 EWM22939.1 - 7.4e-09 34.9 0.0 0.014 15.2 0.0 4.0 4 0 0 4 4 4 2 PPR repeat PPR_2 PF13041.1 EWM22939.1 - 8.3e-08 32.0 0.0 0.089 12.7 0.0 3.8 2 1 2 4 4 4 3 PPR repeat family PPR_1 PF12854.2 EWM22939.1 - 0.0029 17.0 0.3 0.71 9.3 0.0 3.1 3 0 0 3 3 3 1 PPR repeat TPR_14 PF13428.1 EWM22939.1 - 0.0034 17.8 5.0 1.1 10.0 0.0 3.9 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 EWM22939.1 - 0.0053 17.0 0.1 3 8.5 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EWM22939.1 - 0.0081 16.0 1.5 0.34 10.8 0.0 3.3 4 0 0 4 4 3 1 Tetratricopeptide repeat PYRIN PF02758.11 EWM22939.1 - 0.019 14.6 0.2 9 6.0 0.0 3.3 2 1 2 4 4 4 0 PAAD/DAPIN/Pyrin domain TPR_2 PF07719.12 EWM22939.1 - 0.02 14.7 3.5 0.14 12.1 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EWM22939.1 - 0.059 13.7 3.6 1.6 9.1 0.4 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EWM22939.1 - 0.073 12.7 2.5 0.46 10.1 0.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.12 EWM22939.1 - 0.08 13.2 2.2 0.22 11.8 0.0 2.6 2 2 1 3 3 3 0 Bacterial transcriptional activator domain TPR_7 PF13176.1 EWM22939.1 - 0.083 12.7 1.1 1 9.3 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1150 PF06620.6 EWM22939.1 - 0.1 12.4 0.0 0.53 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1150) TPR_16 PF13432.1 EWM22939.1 - 0.11 13.2 5.1 0.68 10.6 0.5 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 EWM22939.1 - 0.17 11.8 5.1 0.44 10.5 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EWM22939.1 - 0.2 12.1 1.5 12 6.5 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Metallophos PF00149.23 EWM22940.1 - 1.1e-24 86.9 0.0 1.9e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_1 PF00036.27 EWM22941.1 - 4.4e-12 44.3 2.3 2.8e-07 29.3 0.1 2.7 2 1 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EWM22941.1 - 2.9e-10 39.5 3.0 1.2e-05 24.7 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 EWM22941.1 - 1.7e-09 36.7 3.6 1.9e-05 24.1 0.0 3.5 3 1 1 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 EWM22941.1 - 8.2e-09 35.4 1.7 3e-05 24.0 0.0 2.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 EWM22941.1 - 1.3e-06 27.4 0.4 1.3e-06 27.4 0.2 2.7 2 1 1 3 3 3 1 EF hand EF-hand_4 PF12763.2 EWM22941.1 - 0.0029 17.3 0.1 0.063 13.0 0.0 2.1 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand WD40 PF00400.27 EWM22942.1 - 1.9e-10 40.2 0.0 3.6e-06 26.6 0.0 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Utp12 PF04003.7 EWM22942.1 - 3.6e-10 39.7 0.8 5.7e-10 39.0 0.6 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family HECT PF00632.20 EWM22943.1 - 1.2e-51 175.8 0.0 1.7e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.23 EWM22943.1 - 8.4e-08 32.3 0.0 5.9e-07 29.5 0.0 2.3 2 0 0 2 2 2 1 SPRY domain MIB_HERC2 PF06701.8 EWM22943.1 - 7.8e-06 25.7 2.1 0.0013 18.6 0.0 3.0 2 0 0 2 2 2 2 Mib_herc2 DUF572 PF04502.8 EWM22943.1 - 0.17 11.0 23.2 0.3 10.2 16.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4045 PF13254.1 EWM22943.1 - 3 7.0 14.2 5 6.3 9.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) AAA_11 PF13086.1 EWM22944.1 - 4.1e-59 200.0 0.0 1.9e-58 197.8 0.0 2.1 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.1 EWM22944.1 - 1.1e-49 168.5 0.0 1.8e-49 167.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EWM22944.1 - 2.5e-14 53.3 9.7 1.4e-10 41.0 0.1 4.6 4 1 0 5 5 4 2 AAA domain AAA_19 PF13245.1 EWM22944.1 - 1e-13 50.8 18.7 2e-13 49.9 0.4 4.5 4 1 0 4 4 3 2 Part of AAA domain AAA_22 PF13401.1 EWM22944.1 - 2.3e-06 27.7 0.0 0.00068 19.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.9 EWM22944.1 - 3.5e-06 26.7 0.0 0.00037 20.1 0.0 2.7 3 0 0 3 3 3 1 Helicase DEAD PF00270.24 EWM22944.1 - 4.2e-06 26.3 0.1 2.3e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Viral_helicase1 PF01443.13 EWM22944.1 - 9.3e-06 25.3 0.0 0.16 11.5 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 EWM22944.1 - 6.1e-05 22.5 0.2 0.0047 16.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 EWM22944.1 - 0.00036 19.8 0.0 0.0079 15.4 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein UvrD-helicase PF00580.16 EWM22944.1 - 0.00074 18.9 0.0 0.0017 17.7 0.0 1.6 2 0 0 2 2 1 1 UvrD/REP helicase N-terminal domain PIF1 PF05970.9 EWM22944.1 - 0.0014 17.6 0.0 0.56 9.0 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase FtsK_SpoIIIE PF01580.13 EWM22944.1 - 0.0019 17.6 0.0 0.0057 16.1 0.0 1.8 1 0 0 1 1 1 1 FtsK/SpoIIIE family DUF2075 PF09848.4 EWM22944.1 - 0.0024 16.9 0.0 0.098 11.6 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Flavi_DEAD PF07652.9 EWM22944.1 - 0.0025 17.5 0.2 0.0064 16.2 0.1 1.7 2 0 0 2 2 1 1 Flavivirus DEAD domain UvrD_C_2 PF13538.1 EWM22944.1 - 0.0067 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.1 EWM22944.1 - 0.0073 16.3 1.4 0.0073 16.3 1.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain TrwB_AAD_bind PF10412.4 EWM22944.1 - 0.0083 14.7 0.0 0.014 14.0 0.0 1.2 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain Zot PF05707.7 EWM22944.1 - 0.0085 15.5 0.0 0.024 14.1 0.0 1.7 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA PF00004.24 EWM22944.1 - 0.011 15.8 0.0 0.027 14.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UvrD_C PF13361.1 EWM22944.1 - 0.013 15.0 0.0 0.73 9.2 0.0 2.1 1 1 1 2 2 2 0 UvrD-like helicase C-terminal domain Herpes_ori_bp PF02399.10 EWM22944.1 - 0.014 13.3 0.1 0.02 12.8 0.1 1.1 1 0 0 1 1 1 0 Origin of replication binding protein ResIII PF04851.10 EWM22944.1 - 0.017 14.9 0.0 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit KaiC PF06745.8 EWM22944.1 - 0.018 14.2 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_17 PF13207.1 EWM22944.1 - 0.032 15.0 0.1 0.12 13.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.10 EWM22944.1 - 0.063 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain IstB_IS21 PF01695.12 EWM22944.1 - 0.077 12.4 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.7 EWM22944.1 - 0.09 12.4 0.0 0.27 10.8 0.0 1.8 2 0 0 2 2 1 0 NACHT domain NTPase_1 PF03266.10 EWM22944.1 - 0.091 12.4 0.4 1.7 8.3 0.0 2.2 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.9 EWM22944.1 - 0.092 12.4 0.0 0.27 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2786 PF10979.3 EWM22944.1 - 0.11 12.2 0.1 0.11 12.2 0.1 2.3 2 0 0 2 2 1 0 Protein of unknown function (DUF2786) AAA_18 PF13238.1 EWM22944.1 - 0.18 12.0 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 EWM22944.1 - 0.2 11.0 0.0 0.5 9.7 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF4140 PF13600.1 EWM22944.1 - 1.7 9.1 7.8 0.38 11.2 0.7 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) IDO PF01231.13 EWM22945.1 - 3.7e-77 259.5 0.0 4.5e-42 143.9 0.0 3.1 2 1 0 2 2 2 2 Indoleamine 2,3-dioxygenase RIO1 PF01163.17 EWM22947.1 - 4.6e-73 244.5 0.0 1.1e-72 243.3 0.0 1.6 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EWM22947.1 - 1.9e-08 34.3 0.7 0.0024 17.6 0.1 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EWM22947.1 - 2.9e-06 26.5 0.5 0.039 13.0 0.1 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Glycos_transf_2 PF00535.21 EWM22948.1 - 0.035 13.7 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Afi1 PF07792.7 EWM22950.1 - 6.2e-23 81.4 0.0 8.4e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 EWM22950.1 - 1.4e-20 73.0 0.0 2.8e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis DUF2347 PF09804.4 EWM22950.1 - 3.2e-07 29.9 0.0 8.9e-05 21.9 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.4 EWM22950.1 - 0.00018 20.1 0.0 2.4 6.5 0.0 3.1 2 1 1 3 3 3 3 Transport protein Avl9 Myb_DNA-binding PF00249.26 EWM22951.1 - 9.9e-34 115.1 14.4 6.5e-12 45.3 0.2 3.9 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EWM22951.1 - 9.7e-33 112.0 8.1 1.2e-13 50.8 0.1 3.8 3 1 1 4 4 4 3 Myb-like DNA-binding domain Rap1_C PF11626.3 EWM22951.1 - 0.0024 17.7 8.2 0.96 9.3 0.1 3.8 2 1 1 4 4 4 3 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-binding PF00249.26 EWM22952.1 - 4e-34 116.4 14.4 5.1e-12 45.6 0.2 4.0 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EWM22952.1 - 4.4e-33 113.1 8.2 9.3e-14 51.2 0.1 3.8 3 1 1 4 4 4 3 Myb-like DNA-binding domain Rap1_C PF11626.3 EWM22952.1 - 0.0013 18.5 8.4 0.67 9.8 0.1 3.9 2 1 1 4 4 4 3 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.1 EWM22952.1 - 4.3 7.5 6.1 17 5.6 0.3 3.2 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain DUF2358 PF10184.4 EWM22953.1 - 2.9e-09 36.8 0.0 4.1e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) DEAD PF00270.24 EWM22954.1 - 3.8e-42 143.6 0.8 9.2e-42 142.3 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EWM22954.1 - 7.2e-28 96.2 0.5 2e-27 94.8 0.3 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EWM22954.1 - 0.0003 20.4 1.1 0.0011 18.6 0.1 2.2 2 0 0 2 2 2 1 Part of AAA domain ResIII PF04851.10 EWM22954.1 - 0.002 17.9 0.0 0.0039 17.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Fanconi_A PF03511.9 EWM22954.1 - 0.0032 17.2 0.1 0.13 12.0 0.1 2.4 2 0 0 2 2 2 1 Fanconi anaemia group A protein AAA_30 PF13604.1 EWM22954.1 - 0.0062 16.1 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF1253 PF06862.7 EWM22954.1 - 0.008 14.6 0.1 0.4 9.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1253) CMS1 PF14617.1 EWM22954.1 - 0.019 14.0 0.0 0.047 12.7 0.0 1.6 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit UvrD-helicase PF00580.16 EWM22954.1 - 0.072 12.3 0.2 0.18 11.0 0.1 1.3 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.9 EWM22954.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.1 EWM22954.1 - 0.13 12.4 0.1 0.49 10.5 0.1 2.0 1 1 0 1 1 1 0 AAA domain PhyH PF05721.8 EWM22955.1 - 0.00031 20.8 0.1 1.1 9.2 0.1 2.9 2 1 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 EWM22955.1 - 0.0045 15.5 0.0 0.057 11.8 0.0 2.2 2 1 1 3 3 3 1 Protein of unknown function (DUF1479) FTZ PF03867.9 EWM22955.1 - 0.058 12.6 0.1 0.08 12.1 0.1 1.1 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region WD40 PF00400.27 EWM22956.1 - 5e-28 95.9 14.0 3.3e-07 29.9 0.8 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat NLE PF08154.7 EWM22956.1 - 9.9e-14 51.1 0.0 1.5e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 EWM22956.1 - 7.1e-05 21.1 5.8 0.083 11.0 0.4 3.3 3 1 0 3 3 3 2 Nucleoporin Nup120/160 Glutaredoxin PF00462.19 EWM22957.1 - 3.4e-20 71.7 0.0 4.9e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 EWM22957.1 - 0.019 15.1 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain 5_3_exonuc_N PF02739.11 EWM22957.1 - 0.024 13.9 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain GST_N_2 PF13409.1 EWM22957.1 - 0.14 12.1 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Malate_synthase PF01274.17 EWM22958.1 - 3.5e-182 606.0 0.0 4.2e-182 605.8 0.0 1.0 1 0 0 1 1 1 1 Malate synthase DUF4460 PF14687.1 EWM22962.1 - 3.1e-18 65.5 0.0 4.3e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4460) Pkinase PF00069.20 EWM22963.1 - 1.3e-54 185.1 0.0 2.3e-54 184.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM22963.1 - 9.4e-38 129.7 0.0 1.5e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.3 EWM22963.1 - 0.019 14.6 0.4 0.087 12.4 0.0 2.1 2 0 0 2 2 2 0 Oxidative-stress-responsive kinase 1 C terminal Rep_3 PF01051.16 EWM22963.1 - 0.81 9.2 3.8 1.3 8.5 2.7 1.2 1 0 0 1 1 1 0 Initiator Replication protein HSP70 PF00012.15 EWM22964.1 - 3.3e-266 883.9 9.5 3.2e-162 540.5 2.9 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 EWM22964.1 - 6.3e-11 41.4 0.7 1.7e-05 23.5 0.1 3.0 3 0 0 3 3 3 2 MreB/Mbl protein PKK PF12474.3 EWM22964.1 - 5 6.8 11.7 0.26 11.0 3.9 1.8 2 0 0 2 2 2 0 Polo kinase kinase FAD_binding_4 PF01565.18 EWM22966.1 - 5.9e-11 41.9 0.0 1.1e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.9 EWM22966.1 - 0.0027 17.3 0.2 0.0048 16.5 0.1 1.4 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase Cortex-I_coil PF09304.5 EWM22967.1 - 0.0049 16.8 16.0 0.0086 16.1 0.6 3.5 3 0 0 3 3 3 2 Cortexillin I, coiled coil Snapin_Pallidin PF14712.1 EWM22967.1 - 0.82 10.0 9.1 4.5 7.6 0.4 3.2 3 0 0 3 3 3 0 Snapin/Pallidin Hemerythrin PF01814.18 EWM22967.1 - 1.1 9.4 5.2 0.72 10.0 0.9 2.3 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain CALCOCO1 PF07888.6 EWM22967.1 - 2.1 6.5 9.8 17 3.5 6.8 2.3 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like GAS PF13851.1 EWM22967.1 - 3.1 6.9 11.0 1.9 7.6 0.7 3.0 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding HAUS-augmin3 PF14932.1 EWM22967.1 - 3.4 6.7 9.4 0.38 9.9 0.4 2.5 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 3 Nup54 PF13874.1 EWM22967.1 - 4.8 6.8 10.6 4.5 6.9 0.1 3.0 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 MscS_porin PF12795.2 EWM22967.1 - 7.2 5.8 14.5 0.7 9.1 1.0 3.1 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain DUF3983 PF13137.1 EWM22968.1 - 0.71 9.6 3.1 1.1 8.9 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3983) APG17 PF04108.7 EWM22969.1 - 7.6e-20 71.0 0.3 8.7e-15 54.4 0.1 2.3 2 0 0 2 2 2 2 Autophagy protein Apg17 WXG100 PF06013.7 EWM22969.1 - 0.1 12.6 4.0 17 5.4 0.1 3.9 3 1 0 3 3 3 0 Proteins of 100 residues with WXG DUF641 PF04859.7 EWM22969.1 - 0.39 10.4 3.4 6.8 6.4 0.7 2.9 1 1 0 2 2 2 0 Plant protein of unknown function (DUF641) Pkinase PF00069.20 EWM22970.1 - 6.1e-35 120.6 0.0 9.5e-35 119.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM22970.1 - 3.9e-20 72.0 0.0 1.1e-19 70.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EWM22970.1 - 0.00012 21.1 0.0 0.00023 20.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EWM22970.1 - 0.052 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-PARP PF00645.13 EWM22971.1 - 2.3e-05 24.5 0.0 5e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region PALP PF00291.20 EWM22973.1 - 0.0015 17.8 0.0 0.0019 17.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PALP PF00291.20 EWM22975.1 - 1.5e-39 136.0 0.2 1.7e-39 135.8 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme adh_short_C2 PF13561.1 EWM22978.1 - 1.4e-11 44.6 0.0 1.9e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TAFII28 PF04719.9 EWM22979.1 - 8.3e-07 28.7 0.4 1.1e-06 28.2 0.3 1.2 1 0 0 1 1 1 1 hTAFII28-like protein conserved region Pro_isomerase PF00160.16 EWM22980.1 - 1.5e-36 125.9 0.1 1.5e-36 125.9 0.0 1.8 2 1 1 3 3 3 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD adh_short_C2 PF13561.1 EWM22981.1 - 6.6e-55 186.4 0.1 7.5e-55 186.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ATP-synt PF00231.14 EWM22982.1 - 1.2e-19 70.7 0.1 1.4e-19 70.5 0.1 1.1 1 0 0 1 1 1 1 ATP synthase WD40 PF00400.27 EWM22983.1 - 7.5e-07 28.8 0.1 0.00044 20.0 0.0 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat DUF547 PF04784.9 EWM22984.1 - 2.8e-21 75.5 0.0 1.4e-20 73.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF547 WD40 PF00400.27 EWM22985.1 - 3.2e-20 71.1 1.6 1.1e-05 25.0 0.3 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat HTH_27 PF13463.1 EWM22987.1 - 0.0083 16.4 0.2 0.15 12.4 0.0 2.4 2 0 0 2 2 2 1 Winged helix DNA-binding domain HemN_C PF06969.11 EWM22987.1 - 0.078 13.0 0.4 0.22 11.6 0.1 1.9 2 0 0 2 2 2 0 HemN C-terminal domain Mrr_N PF14338.1 EWM22987.1 - 0.15 12.2 0.1 0.64 10.1 0.0 2.1 2 0 0 2 2 2 0 Mrr N-terminal domain EFG_C PF00679.19 EWM22989.1 - 4.7e-26 90.4 0.0 6.8e-26 89.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.13 EWM22989.1 - 2.1e-10 40.1 0.2 4.4e-10 39.1 0.1 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV Spatacsin_C PF14649.1 EWM22989.1 - 0.17 10.6 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Spatacsin C-terminus tRNA-synt_2d PF01409.15 EWM22990.1 - 2.6e-56 190.6 0.0 3.1e-56 190.3 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 EWM22990.1 - 1.4e-05 24.0 0.0 2.4e-05 23.3 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EWM22990.1 - 3.3e-05 23.5 0.0 7.7e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) EFG_II PF14492.1 EWM22991.1 - 1.1e-31 108.5 0.0 1.6e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EWM22991.1 - 1.3e-08 34.7 0.0 2.7e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 EWM22991.1 - 0.0012 18.4 0.1 0.0031 17.0 0.0 1.7 2 0 0 2 2 2 1 Elongation factor G, domain IV GTP_EFTU PF00009.22 EWM22993.1 - 1.2e-09 37.8 0.1 1.6e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Pribosyltran PF00156.22 EWM22995.1 - 0.097 12.3 0.0 0.17 11.6 0.0 1.5 1 1 0 1 1 1 0 Phosphoribosyl transferase domain FUSC_2 PF13515.1 EWM22996.1 - 6.7e-11 42.2 12.5 1.1e-10 41.5 8.6 1.4 1 0 0 1 1 1 1 Fusaric acid resistance protein-like FUSC PF04632.7 EWM22996.1 - 1.4e-10 40.2 7.4 2.4e-10 39.5 5.1 1.3 1 0 0 1 1 1 1 Fusaric acid resistance protein family ALMT PF11744.3 EWM22996.1 - 2e-08 33.2 0.9 4.4e-08 32.2 0.6 1.4 1 1 0 1 1 1 1 Aluminium activated malate transporter DUF939 PF06081.6 EWM22996.1 - 0.039 13.8 1.6 0.078 12.8 1.1 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF939) Erythrovirus_X PF06795.6 EWM22996.1 - 0.059 13.4 0.2 0.21 11.6 0.0 2.1 2 0 0 2 2 2 0 Erythrovirus X protein IMPDH PF00478.20 EWM22998.1 - 2e-06 26.9 0.0 2.4e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain SufE PF02657.10 EWM23002.1 - 0.026 14.1 0.0 0.028 14.0 0.0 1.1 1 0 0 1 1 1 0 Fe-S metabolism associated domain DUF935 PF06074.7 EWM23006.1 - 0.074 11.7 0.2 0.08 11.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF935) DUF935 PF06074.7 EWM23008.1 - 0.073 11.7 0.1 0.096 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF935) 7TM_GPCR_Sri PF10327.4 EWM23010.1 - 0.08 11.8 0.1 0.11 11.3 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri DUF962 PF06127.6 EWM23011.1 - 3.7e-19 68.4 9.7 4.1e-19 68.2 3.7 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF962) FoP_duplication PF13865.1 EWM23013.1 - 5.8 7.4 7.4 7.7 7.0 5.1 1.2 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 zf-C2H2 PF00096.21 EWM23016.1 - 0.0045 17.2 0.2 0.015 15.6 0.2 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-BED PF02892.10 EWM23016.1 - 0.048 13.4 0.1 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 BED zinc finger zf-C2H2_4 PF13894.1 EWM23016.1 - 0.23 11.8 0.0 0.23 11.8 0.0 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger Glyco_hydro_6 PF01341.12 EWM23017.1 - 0.04 13.3 0.0 0.049 13.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 6 Cyt-b5 PF00173.23 EWM23019.1 - 1e-12 47.6 0.0 1.5e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TMEM171 PF15471.1 EWM23020.1 - 1 8.0 3.9 0.99 8.1 1.6 1.7 1 1 1 2 2 2 0 Transmembrane protein family 171 PLA2_B PF01735.13 EWM23023.1 - 1.1e-25 89.7 8.7 3.6e-11 41.9 0.0 3.7 3 1 0 3 3 3 3 Lysophospholipase catalytic domain Patatin PF01734.17 EWM23023.1 - 0.0047 16.8 6.1 0.011 15.6 2.0 3.1 3 1 0 3 3 3 1 Patatin-like phospholipase Phage_Mu_Gam PF07352.7 EWM23030.1 - 0.0011 18.5 12.8 0.019 14.4 2.6 2.3 1 1 1 2 2 2 2 Bacteriophage Mu Gam like protein SAGA-Tad1 PF12767.2 EWM23030.1 - 0.032 13.9 1.5 0.036 13.7 1.1 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF1451 PF07295.6 EWM23030.1 - 0.053 13.3 4.6 0.044 13.5 2.3 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1451) HemX PF04375.9 EWM23030.1 - 0.066 11.7 6.3 0.079 11.5 4.4 1.0 1 0 0 1 1 1 0 HemX DUF4618 PF15397.1 EWM23030.1 - 0.14 11.4 5.3 0.19 11.0 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Sulfotransfer_2 PF03567.9 EWM23030.1 - 0.21 11.2 1.0 0.3 10.7 0.7 1.4 1 1 0 1 1 1 0 Sulfotransferase family Prominin PF05478.6 EWM23030.1 - 0.36 8.3 1.4 0.42 8.0 1.0 1.1 1 0 0 1 1 1 0 Prominin Remorin_C PF03763.8 EWM23030.1 - 0.43 10.1 9.7 0.61 9.6 6.7 1.2 1 0 0 1 1 1 0 Remorin, C-terminal region DUF1628 PF07790.6 EWM23030.1 - 0.43 11.3 2.5 0.63 10.8 1.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1628) Snapin_Pallidin PF14712.1 EWM23030.1 - 0.52 10.6 5.2 0.64 10.3 2.8 1.7 1 1 1 2 2 2 0 Snapin/Pallidin DUF4473 PF14747.1 EWM23030.1 - 0.54 10.5 4.6 4.9 7.4 0.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4473) DUF1690 PF07956.6 EWM23030.1 - 0.58 10.1 5.3 0.72 9.8 3.4 1.4 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) DUF2992 PF11208.3 EWM23030.1 - 0.79 9.6 6.3 1.2 8.9 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) DivIVA PF05103.8 EWM23030.1 - 5.9 6.9 13.0 3 7.9 4.3 2.2 1 1 1 2 2 2 0 DivIVA protein Phage_Mu_Gam PF07352.7 EWM23032.1 - 0.0068 15.9 14.0 0.13 11.7 4.6 3.0 1 1 1 2 2 2 2 Bacteriophage Mu Gam like protein DUF2580 PF10824.3 EWM23032.1 - 0.049 13.9 1.2 0.049 13.9 0.8 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2580) DUF1690 PF07956.6 EWM23032.1 - 0.078 12.9 10.6 0.18 11.8 3.1 2.0 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) SAGA-Tad1 PF12767.2 EWM23032.1 - 0.096 12.3 3.0 0.12 11.9 2.1 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Sulfotransfer_2 PF03567.9 EWM23032.1 - 0.18 11.4 0.8 0.28 10.8 0.3 1.4 1 1 0 1 1 1 0 Sulfotransferase family Prominin PF05478.6 EWM23032.1 - 0.34 8.3 2.2 0.44 8.0 1.6 1.1 1 0 0 1 1 1 0 Prominin Terminase_3 PF04466.8 EWM23032.1 - 0.4 9.7 5.3 0.64 9.0 3.7 1.5 1 1 0 1 1 1 0 Phage terminase large subunit DUF3010 PF11215.3 EWM23032.1 - 0.53 10.2 3.6 2.2 8.1 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3010) DUF3826 PF12875.2 EWM23032.1 - 0.62 9.7 9.6 0.67 9.6 6.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3826) DUF1640 PF07798.6 EWM23032.1 - 1.1 9.2 8.8 1.9 8.4 6.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF3437 PF11919.3 EWM23032.1 - 9.9 5.9 7.9 18 5.1 1.1 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3437) Phage_Mu_Gam PF07352.7 EWM23033.1 - 0.015 14.8 13.9 0.074 12.5 2.9 2.7 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein Terminase_3 PF04466.8 EWM23033.1 - 0.018 14.1 1.8 0.019 14.0 1.2 1.1 1 0 0 1 1 1 0 Phage terminase large subunit SAGA-Tad1 PF12767.2 EWM23033.1 - 0.05 13.2 1.8 0.06 12.9 1.3 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF3826 PF12875.2 EWM23033.1 - 0.068 12.8 6.7 0.029 14.0 2.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3826) Neur PF00064.13 EWM23033.1 - 0.15 10.0 0.3 0.18 9.8 0.2 1.1 1 0 0 1 1 1 0 Neuraminidase RNaseH_C PF09293.5 EWM23033.1 - 0.69 9.8 5.2 1.2 9.0 0.5 2.2 1 1 1 2 2 2 0 T4 RNase H, C terminal CAF-1_p150 PF11600.3 EWM23033.1 - 2.5 7.4 14.5 3.3 7.0 10.1 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Glyoxalase_2 PF12681.2 EWM23035.1 - 7.6e-10 39.3 0.0 3.1e-09 37.4 0.0 1.8 2 0 0 2 2 2 1 Glyoxalase-like domain Glyoxalase PF00903.20 EWM23035.1 - 3.4e-09 36.7 0.0 5e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EWM23035.1 - 0.0049 16.8 0.0 0.012 15.5 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Cache_3 PF14827.1 EWM23035.1 - 0.019 14.8 0.2 0.033 14.0 0.1 1.4 1 0 0 1 1 1 0 Sensory domain of two-component sensor kinase DUF3081 PF11280.3 EWM23035.1 - 0.027 14.0 0.2 0.065 12.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3081) Nuc_sug_transp PF04142.10 EWM23038.1 - 8.9e-19 67.5 0.7 1.4e-18 66.9 0.5 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 EWM23038.1 - 1.4 8.9 10.7 0.076 13.0 1.2 2.9 2 2 0 3 3 3 0 EamA-like transporter family Glyoxalase PF00903.20 EWM23040.1 - 0.036 14.0 0.0 0.075 13.0 0.0 1.5 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DRMBL PF07522.9 EWM23043.1 - 2.8e-14 53.0 0.0 4.9e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EWM23043.1 - 1.1e-10 41.4 0.0 5.1e-10 39.2 0.0 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EWM23043.1 - 0.0001 22.0 0.0 0.00026 20.7 0.0 1.7 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 EWM23043.1 - 0.0053 16.4 2.2 0.014 15.0 1.6 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Mito_fiss_reg PF05308.6 EWM23044.1 - 1.3 8.3 9.8 0.45 9.8 1.7 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator Sensor PF13796.1 EWM23045.1 - 2.2 7.8 3.6 0.57 9.7 0.3 1.7 2 0 0 2 2 2 0 Putative sensor RRM_1 PF00076.17 EWM23046.1 - 1.2e-19 69.7 0.1 9.3e-17 60.4 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM23046.1 - 6e-13 48.5 0.0 4e-11 42.7 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM23046.1 - 0.00022 20.9 0.0 0.00036 20.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Myc_N PF01056.13 EWM23047.1 - 0.35 9.9 1.6 0.51 9.4 1.1 1.2 1 0 0 1 1 1 0 Myc amino-terminal region AMP-binding PF00501.23 EWM23049.1 - 8.4e-40 136.4 1.0 3e-34 118.1 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme RRM_1 PF00076.17 EWM23050.1 - 0.00062 19.3 0.0 0.00093 18.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BCDHK_Adom3 PF10436.4 EWM23051.1 - 2.5e-29 101.8 0.0 3.9e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EWM23051.1 - 6.5e-11 41.9 0.0 2.3e-09 36.9 0.0 2.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cupin_8 PF13621.1 EWM23052.1 - 1.2e-29 103.5 0.0 2.6e-17 63.1 0.0 2.1 2 0 0 2 2 2 2 Cupin-like domain DUF605 PF04652.11 EWM23054.1 - 0.21 10.9 6.7 0.26 10.6 4.6 1.1 1 0 0 1 1 1 0 Vta1 like WD40 PF00400.27 EWM23056.1 - 4.7e-15 54.7 0.2 2e-08 33.7 0.2 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat Cob_adeno_trans PF01923.13 EWM23057.1 - 1e-24 87.1 0.0 1.2e-24 87.0 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase tRNA_anti-codon PF01336.20 EWM23061.1 - 0.033 14.0 0.2 0.059 13.2 0.1 1.5 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain Voldacs PF03517.8 EWM23064.1 - 0.15 11.8 0.5 0.25 11.1 0.3 1.3 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling CDC27 PF09507.5 EWM23064.1 - 9.3 5.3 11.6 13 4.8 8.0 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 zf-DNL PF05180.7 EWM23067.1 - 2.6e-26 91.1 0.0 4.1e-26 90.4 0.0 1.3 1 0 0 1 1 1 1 DNL zinc finger Atg8 PF02991.11 EWM23068.1 - 7.9e-33 112.5 0.1 1.2e-32 111.9 0.1 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EWM23068.1 - 0.0023 18.0 0.0 0.0042 17.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Abhydrolase_6 PF12697.2 EWM23072.1 - 1.1e-11 45.0 1.5 2e-11 44.2 0.1 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EWM23072.1 - 0.0015 18.3 0.0 0.0031 17.3 0.0 1.6 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 EWM23072.1 - 0.01 15.5 0.1 0.021 14.5 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase family EHN PF06441.7 EWM23072.1 - 0.032 14.1 0.1 0.045 13.6 0.1 1.2 1 0 0 1 1 1 0 Epoxide hydrolase N terminus Abhydro_lipase PF04083.11 EWM23072.1 - 0.039 13.3 0.1 0.06 12.7 0.1 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region KOW PF00467.24 EWM23073.1 - 2.9e-07 29.9 2.3 4.6e-07 29.2 0.7 2.0 2 0 0 2 2 2 1 KOW motif DAO PF01266.19 EWM23074.1 - 0.00024 20.1 0.0 0.00038 19.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EWM23074.1 - 0.00058 19.8 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EWM23074.1 - 0.12 11.3 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain PAT1 PF09770.4 EWM23075.1 - 4 5.5 8.4 5 5.2 5.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Macoilin PF09726.4 EWM23076.1 - 1.2 7.3 4.0 1.5 7.0 2.7 1.1 1 0 0 1 1 1 0 Transmembrane protein HMA PF00403.21 EWM23077.1 - 7.8e-05 22.7 0.2 7.8e-05 22.7 0.1 1.6 2 0 0 2 2 2 1 Heavy-metal-associated domain Pyr_redox_2 PF07992.9 EWM23080.1 - 5e-14 52.6 0.0 5e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EWM23080.1 - 7e-08 31.7 2.9 9.8e-08 31.2 2.0 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EWM23080.1 - 2.7e-07 29.8 0.8 3.2e-07 29.5 0.6 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EWM23080.1 - 1.3e-06 27.7 0.8 1.6e-06 27.4 0.5 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EWM23080.1 - 5.7e-06 25.0 0.3 6.7e-06 24.8 0.2 1.1 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EWM23080.1 - 1.3e-05 24.4 0.2 1.8e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 EWM23080.1 - 2.8e-05 24.0 0.6 5.4e-05 23.1 0.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EWM23080.1 - 3.1e-05 23.0 0.2 3.2e-05 22.9 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EWM23080.1 - 0.03 14.3 0.3 0.039 14.0 0.2 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EWM23080.1 - 0.041 14.2 0.5 0.062 13.7 0.4 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EWM23080.1 - 0.06 12.2 0.2 0.079 11.8 0.1 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 EWM23080.1 - 0.076 12.0 0.6 0.12 11.4 0.1 1.5 2 0 0 2 2 2 0 FAD binding domain NAD_Gly3P_dh_N PF01210.18 EWM23080.1 - 0.1 12.3 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.16 EWM23080.1 - 0.15 11.6 0.1 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Malic_M PF03949.10 EWM23084.1 - 5.3e-24 85.1 0.0 6.1e-24 84.9 0.0 1.0 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EWM23085.1 - 2.5e-38 131.4 0.0 4.1e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Scs3p PF10261.4 EWM23085.1 - 0.049 12.6 0.2 0.073 12.0 0.1 1.1 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM MatE PF01554.13 EWM23087.1 - 7.1e-07 28.9 1.5 1.1e-06 28.3 1.1 1.3 1 0 0 1 1 1 1 MatE Apq12 PF12716.2 EWM23087.1 - 0.2 11.3 2.5 0.59 9.8 1.7 1.7 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis FTHFS PF01268.14 EWM23087.1 - 0.21 9.5 0.1 0.27 9.1 0.1 1.0 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase Ras PF00071.17 EWM23088.1 - 3.8e-45 153.1 0.0 4.7e-45 152.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EWM23088.1 - 5.5e-19 68.8 0.0 7.3e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EWM23088.1 - 8.3e-07 28.4 0.0 1.1e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MatE PF01554.13 EWM23089.1 - 1.5e-18 66.9 3.5 2.4e-18 66.2 2.4 1.3 1 0 0 1 1 1 1 MatE Polysacc_synt_C PF14667.1 EWM23089.1 - 5.8e-05 22.9 5.7 6.5e-05 22.7 1.0 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis C-terminal domain MVIN PF03023.9 EWM23089.1 - 0.0011 17.4 0.9 0.0015 17.0 0.6 1.2 1 0 0 1 1 1 1 MviN-like protein TPR_6 PF13174.1 EWM23090.1 - 0.047 14.1 3.3 0.19 12.2 0.2 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EWM23090.1 - 0.055 13.1 0.1 0.098 12.3 0.1 1.4 1 0 0 1 1 1 0 TPR repeat TPR_16 PF13432.1 EWM23090.1 - 0.17 12.6 1.4 0.68 10.6 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EWM23090.1 - 1.3 9.1 4.6 0.42 10.6 1.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat WD40 PF00400.27 EWM23091.1 - 1.6e-14 53.0 0.4 0.0001 22.0 0.0 7.0 8 0 0 8 8 8 4 WD domain, G-beta repeat Lactonase PF10282.4 EWM23091.1 - 0.013 14.6 0.0 0.032 13.3 0.0 1.7 1 1 0 1 1 1 0 Lactonase, 7-bladed beta-propeller DUF788 PF05620.6 EWM23092.1 - 2e-15 57.0 0.5 3e-15 56.5 0.4 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF788) CoA_binding_3 PF13727.1 EWM23092.1 - 3.1 7.5 8.4 0.23 11.2 0.4 2.1 1 1 1 2 2 2 0 CoA-binding domain ABC_tran PF00005.22 EWM23093.1 - 5.6e-45 153.0 0.0 3.7e-31 108.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EWM23093.1 - 1.7e-34 119.4 9.9 2.4e-34 119.0 6.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EWM23093.1 - 4.4e-15 55.5 0.0 9.5e-07 28.2 0.0 2.9 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EWM23093.1 - 7.9e-07 29.3 0.1 0.39 10.6 0.0 3.2 2 1 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EWM23093.1 - 5.4e-05 23.2 3.5 0.00029 20.8 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EWM23093.1 - 0.00035 20.0 2.4 0.043 13.2 0.8 3.2 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EWM23093.1 - 0.00048 19.6 0.1 0.0024 17.3 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EWM23093.1 - 0.00083 19.2 6.8 0.25 11.2 0.4 3.9 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.4 EWM23093.1 - 0.0015 17.1 1.4 0.27 9.7 0.0 3.1 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_22 PF13401.1 EWM23093.1 - 0.0078 16.3 2.5 0.44 10.6 0.7 3.2 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 EWM23093.1 - 0.013 15.6 5.0 8.5 6.5 0.1 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EWM23093.1 - 0.025 14.0 0.4 0.28 10.5 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain RICH PF05062.7 EWM23093.1 - 0.059 13.5 1.3 0.4 10.8 0.1 2.2 2 0 0 2 2 2 0 RICH domain MobB PF03205.9 EWM23093.1 - 0.072 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EWM23093.1 - 0.073 12.9 0.1 0.19 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EWM23093.1 - 0.096 11.8 0.1 0.53 9.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 EWM23093.1 - 0.35 11.7 3.1 0.92 10.3 1.1 2.5 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EWM23094.1 - 8e-16 58.5 0.0 9.1e-16 58.4 0.0 1.0 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 EWM23094.1 - 0.00015 21.2 0.0 0.00023 20.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EWM23094.1 - 0.00084 19.3 0.0 0.00093 19.2 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 EWM23094.1 - 0.0013 17.8 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 EWM23094.1 - 0.0016 18.5 0.0 0.0019 18.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 EWM23094.1 - 0.0024 17.8 0.0 0.0025 17.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EWM23094.1 - 0.0027 16.8 0.0 0.0031 16.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EWM23094.1 - 0.0032 18.2 0.0 0.0039 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EWM23094.1 - 0.0041 16.9 0.0 0.0049 16.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EWM23094.1 - 0.019 15.2 0.0 0.021 15.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EWM23094.1 - 0.032 13.9 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EWM23094.1 - 0.069 12.5 0.1 0.086 12.2 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain APS_kinase PF01583.15 EWM23094.1 - 0.087 12.4 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Adenylylsulphate kinase Rad17 PF03215.10 EWM23094.1 - 0.087 11.4 0.0 0.095 11.3 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein FtsK_SpoIIIE PF01580.13 EWM23094.1 - 0.11 11.9 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SE PF00437.15 EWM23094.1 - 0.13 11.0 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein LRR_6 PF13516.1 EWM23095.1 - 2.7e-12 45.4 12.6 0.016 15.1 0.0 9.2 12 0 0 12 12 12 2 Leucine Rich repeat LRR_4 PF12799.2 EWM23095.1 - 1.1e-08 34.4 0.4 1.4 8.6 0.0 7.4 8 1 0 8 8 8 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EWM23095.1 - 3.5e-05 23.2 8.3 33 5.0 0.0 8.1 9 1 1 10 10 10 0 Leucine Rich Repeat LRR_8 PF13855.1 EWM23095.1 - 0.0037 16.9 7.4 46 3.8 0.1 7.3 8 2 1 9 9 8 0 Leucine rich repeat LRR_7 PF13504.1 EWM23095.1 - 0.099 12.9 13.9 41 5.0 0.0 8.1 11 0 0 11 11 11 0 Leucine rich repeat Trypsin_2 PF13365.1 EWM23097.1 - 5.4e-16 58.6 0.0 1.1e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 EWM23097.1 - 7.8e-12 45.2 0.0 1.4e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.1 EWM23097.1 - 1.8e-07 30.9 0.0 1.6e-06 27.9 0.0 2.2 2 0 0 2 2 2 1 PDZ domain Peptidase_S46 PF10459.4 EWM23097.1 - 0.0025 16.3 0.5 0.062 11.7 0.1 2.6 2 1 0 3 3 3 1 Peptidase S46 PDZ PF00595.19 EWM23097.1 - 0.0052 16.9 0.0 0.032 14.3 0.0 2.1 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) Peptidase_S29 PF02907.10 EWM23097.1 - 0.068 12.6 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease Peptidase_S7 PF00949.16 EWM23097.1 - 0.069 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease ABC_membrane PF00664.18 EWM23098.1 - 6.8e-47 160.1 2.1 8.2e-47 159.9 1.5 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF4282 PF14110.1 EWM23098.1 - 1.4 9.1 0.0 1.4 9.1 0.0 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4282) adh_short PF00106.20 EWM23099.1 - 1.1e-21 77.5 1.0 2e-21 76.6 0.7 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EWM23099.1 - 4.4e-10 39.7 0.0 6.4e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EWM23099.1 - 3.9e-05 23.3 0.2 7.5e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EWM23099.1 - 0.0045 16.1 0.0 0.011 14.9 0.0 1.7 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) RabGAP-TBC PF00566.13 EWM23100.1 - 1.2e-27 96.7 0.0 5.6e-27 94.6 0.0 2.0 2 1 0 2 2 2 1 Rab-GTPase-TBC domain GFO_IDH_MocA PF01408.17 EWM23104.1 - 1.1e-25 90.4 0.1 1.4e-25 90.0 0.1 1.1 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 EWM23104.1 - 0.00021 21.5 0.0 0.00036 20.8 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EWM23104.1 - 0.0064 15.5 0.2 0.011 14.7 0.2 1.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase 2-Hacid_dh_C PF02826.14 EWM23104.1 - 0.013 14.7 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.16 EWM23104.1 - 0.016 15.0 0.2 0.028 14.2 0.1 1.4 1 0 0 1 1 1 0 ThiF family OCD_Mu_crystall PF02423.10 EWM23104.1 - 0.02 13.6 0.5 0.035 12.8 0.3 1.4 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family NAD_binding_3 PF03447.11 EWM23104.1 - 0.046 14.1 0.1 0.077 13.3 0.0 1.5 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain CoA_binding PF02629.14 EWM23104.1 - 0.1 13.1 1.4 0.14 12.7 0.2 1.8 2 1 0 2 2 2 0 CoA binding domain AAA_33 PF13671.1 EWM23105.1 - 0.005 16.7 0.0 0.0067 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EWM23105.1 - 0.013 16.3 0.0 0.052 14.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EWM23105.1 - 0.041 12.9 0.0 0.063 12.3 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.1 EWM23105.1 - 0.054 13.6 0.0 0.13 12.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EWM23105.1 - 0.12 12.3 0.1 0.22 11.5 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 EWM23105.1 - 0.15 11.4 0.0 0.4 10.0 0.0 1.6 1 1 0 1 1 1 0 AAA-like domain Sec16_C PF12931.2 EWM23106.1 - 0.0015 18.3 0.1 1.5 8.5 0.0 3.1 3 1 0 3 3 3 2 Sec23-binding domain of Sec16 NAD_binding_2 PF03446.10 EWM23107.1 - 8.4e-38 129.7 0.4 2.4e-37 128.2 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EWM23107.1 - 1.5e-25 89.6 1.4 3.1e-25 88.5 1.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EWM23107.1 - 4.9e-07 30.0 0.0 2.2e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EWM23107.1 - 1.4e-05 25.1 0.0 2.7e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 EWM23107.1 - 0.0001 21.5 0.0 0.00016 20.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 EWM23107.1 - 0.0026 17.7 0.0 0.0054 16.7 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 EWM23107.1 - 0.02 13.8 0.0 0.03 13.2 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase 3HCDH_N PF02737.13 EWM23107.1 - 0.043 13.4 0.0 0.21 11.2 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IF2_N PF04760.10 EWM23107.1 - 0.068 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region UDPG_MGDP_dh_N PF03721.9 EWM23107.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_oxidored PF12831.2 EWM23108.1 - 1.3e-05 24.4 0.1 1.5e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EWM23108.1 - 2.1e-05 23.1 0.2 2.8e-05 22.8 0.1 1.1 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EWM23108.1 - 3.3e-05 23.8 0.1 4.5e-05 23.4 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EWM23108.1 - 6.5e-05 21.9 0.2 9e-05 21.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EWM23108.1 - 0.0021 18.0 0.0 0.0038 17.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EWM23108.1 - 0.019 13.8 0.1 0.028 13.3 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 EWM23108.1 - 0.059 12.2 0.1 0.075 11.8 0.1 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.12 EWM23108.1 - 0.073 12.1 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 EWM23109.1 - 4.8e-10 39.6 0.0 6.4e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EWM23109.1 - 0.012 15.3 0.0 0.013 15.1 0.0 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 EWM23109.1 - 0.02 14.8 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 EWM23109.1 - 0.048 13.6 0.0 0.059 13.3 0.0 1.1 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.1 EWM23109.1 - 0.13 12.2 0.1 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EWM23110.1 - 2.5e-28 98.2 0.3 4.1e-28 97.6 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Lactamase_B PF00753.22 EWM23111.1 - 7e-10 38.8 0.1 8.6e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EWM23111.1 - 1.9e-06 27.5 0.1 2.3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EWM23111.1 - 7.4e-05 22.5 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF3728 PF12528.3 EWM23112.1 - 0.099 13.0 0.1 0.31 11.4 0.0 1.8 2 0 0 2 2 2 0 Prepilin peptidase dependent protein C (DUF3728) Nol1_Nop2_Fmu PF01189.12 EWM23117.1 - 1.3e-20 74.0 0.0 1.8e-15 57.1 0.0 2.3 2 0 0 2 2 2 2 NOL1/NOP2/sun family CPSF73-100_C PF11718.3 EWM23119.1 - 3.1e-10 39.7 0.0 4.1e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term GOLD_2 PF13897.1 EWM23121.1 - 2e-09 37.7 5.7 0.00055 20.1 0.0 3.1 2 1 1 3 3 3 2 Golgi-dynamics membrane-trafficking DSPc PF00782.15 EWM23121.1 - 5.6e-05 22.7 0.0 9.1e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain TPD52 PF04201.10 EWM23121.1 - 0.42 10.3 9.2 0.11 12.2 1.3 2.3 2 0 0 2 2 2 0 Tumour protein D52 family IncA PF04156.9 EWM23121.1 - 6 6.4 10.1 0.074 12.6 0.3 2.0 2 0 0 2 2 2 0 IncA protein F-box PF00646.28 EWM23124.1 - 0.00076 19.0 0.9 0.0015 18.1 0.1 1.9 2 0 0 2 2 2 1 F-box domain Ribosomal_L24e PF01246.15 EWM23125.1 - 6.3e-29 99.6 2.5 1.4e-28 98.5 1.8 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e NGF PF00243.13 EWM23125.1 - 0.017 14.8 0.4 0.03 14.0 0.1 1.6 1 1 0 1 1 1 0 Nerve growth factor family DUF2175 PF09943.4 EWM23125.1 - 0.95 9.5 3.3 0.67 10.0 0.6 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) adh_short PF00106.20 EWM23126.1 - 5.2e-28 98.0 0.4 8.5e-28 97.3 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EWM23126.1 - 8.4e-13 48.3 0.2 1.2e-12 47.8 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EWM23126.1 - 0.00035 19.8 0.0 0.001 18.2 0.0 1.8 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 EWM23126.1 - 0.0013 18.4 0.0 0.003 17.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short_C2 PF13561.1 EWM23126.1 - 0.003 17.3 0.0 0.0041 16.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EWM23126.1 - 0.0097 15.3 0.1 0.019 14.4 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DNA_pol_B PF00136.16 EWM23127.1 - 2.5e-141 471.6 0.0 3.5e-141 471.1 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EWM23127.1 - 6.7e-72 242.0 0.0 1e-71 241.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EWM23127.1 - 2.9e-21 75.2 4.5 5.4e-21 74.3 3.1 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 EWM23127.1 - 0.0021 17.9 0.0 0.015 15.0 0.0 2.2 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_2 PF03175.8 EWM23127.1 - 0.17 10.5 0.5 0.67 8.5 0.0 2.1 2 1 0 2 2 2 0 DNA polymerase type B, organellar and viral C1_1 PF00130.17 EWM23127.1 - 1.6 8.5 5.5 5.5 6.7 3.8 1.9 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DNA_pol_B PF00136.16 EWM23128.1 - 1.9e-117 392.9 0.0 2.5e-117 392.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EWM23128.1 - 4.1e-72 242.8 0.0 6.1e-72 242.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain RNase_H_2 PF13482.1 EWM23128.1 - 0.0012 18.7 0.0 0.011 15.5 0.0 2.2 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_2 PF03175.8 EWM23128.1 - 0.091 11.4 0.5 0.46 9.1 0.0 2.2 2 1 0 2 2 2 0 DNA polymerase type B, organellar and viral TPM PF04536.9 EWM23129.1 - 6e-12 45.4 0.0 8.8e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase Ribosomal_S4 PF00163.14 EWM23131.1 - 4.1e-24 84.7 1.2 4.1e-24 84.7 0.8 1.9 2 1 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EWM23131.1 - 5.8e-11 41.6 1.0 5.8e-11 41.6 0.7 2.3 2 0 0 2 2 2 1 S4 domain PP2C PF00481.16 EWM23132.1 - 1.3e-12 47.6 0.0 2e-05 24.1 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C ATE_N PF04376.8 EWM23133.1 - 4.2e-25 87.3 4.8 7.3e-25 86.5 3.3 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Pirin_C PF05726.8 EWM23134.1 - 3.5e-11 43.0 0.0 9.1e-11 41.7 0.0 1.7 1 1 0 1 1 1 1 Pirin C-terminal cupin domain Pirin PF02678.11 EWM23134.1 - 9.9e-06 25.3 0.0 1.9e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Pirin PEP-utilizers_C PF02896.13 EWM23135.1 - 1.7e-82 276.6 0.0 2.7e-82 275.9 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.14 EWM23135.1 - 1.5e-58 198.3 0.0 4.1e-58 196.9 0.0 1.7 1 1 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.18 EWM23135.1 - 3.8e-20 71.2 3.1 3.8e-20 71.2 2.1 2.1 2 0 0 2 2 2 1 PEP-utilising enzyme, mobile domain Glyco_hydro_16 PF00722.16 EWM23136.1 - 4.4e-18 65.2 0.3 1.9e-17 63.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Sel1 PF08238.7 EWM23137.1 - 1.6e-26 92.0 54.6 6.8e-08 32.9 0.8 12.4 14 0 0 14 14 14 7 Sel1 repeat TPR_11 PF13414.1 EWM23137.1 - 0.00097 18.7 15.1 0.016 14.8 3.6 6.0 5 1 1 6 6 6 2 TPR repeat TPR_16 PF13432.1 EWM23137.1 - 0.0043 17.6 6.8 0.0043 17.6 4.7 6.7 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 EWM23137.1 - 0.0048 17.1 4.2 0.0048 17.1 2.9 6.1 6 3 1 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 EWM23137.1 - 0.24 11.2 17.4 3.7 7.5 0.1 7.3 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_1 PF00515.23 EWM23137.1 - 0.24 11.0 8.9 2.3 7.9 0.1 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 EWM23137.1 - 1.7 8.6 17.9 5.7 6.9 3.5 6.2 4 2 1 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.20 EWM23138.1 - 8.7e-61 205.3 0.0 1.1e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM23138.1 - 7.4e-38 130.1 0.0 1e-37 129.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EWM23138.1 - 4.7e-07 29.0 0.0 7.1e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Cellulase PF00150.13 EWM23139.1 - 7.2e-32 110.7 0.0 9.6e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Sigma70_r2 PF04542.9 EWM23140.1 - 2.3e-20 71.9 0.2 4.4e-20 71.0 0.2 1.5 1 0 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.11 EWM23140.1 - 1.7e-19 68.8 1.0 3.7e-18 64.5 0.6 3.0 3 0 0 3 3 3 1 Sigma-70, region 4 Sigma70_r3 PF04539.11 EWM23140.1 - 1.8e-18 66.1 2.7 1e-13 50.9 0.1 3.4 3 0 0 3 3 3 2 Sigma-70 region 3 Sigma70_r4_2 PF08281.7 EWM23140.1 - 0.022 14.2 1.0 0.5 9.8 0.1 3.2 3 0 0 3 3 3 0 Sigma-70, region 4 AFG1_ATPase PF03969.11 EWM23141.1 - 3.3e-90 302.5 1.0 3.7e-63 213.5 0.1 2.1 1 1 0 2 2 2 2 AFG1-like ATPase Bac_DnaA PF00308.13 EWM23141.1 - 0.015 14.9 0.0 0.13 11.8 0.0 2.3 2 1 0 2 2 2 0 Bacterial dnaA protein AAA_16 PF13191.1 EWM23141.1 - 0.028 14.4 0.0 0.15 12.0 0.0 2.3 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.12 EWM23141.1 - 0.049 13.0 0.0 0.094 12.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Nup160 PF11715.3 EWM23142.1 - 0.0029 15.7 0.1 1.6 6.7 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Proteasome PF00227.21 EWM23143.1 - 3.5e-38 130.8 0.0 5.7e-38 130.1 0.0 1.3 2 0 0 2 2 2 1 Proteasome subunit Rad17 PF03215.10 EWM23144.1 - 1e-26 93.7 0.0 1e-13 50.8 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 EWM23144.1 - 0.00045 20.2 1.0 0.0021 18.0 0.2 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EWM23144.1 - 0.0039 18.0 0.0 0.012 16.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EWM23144.1 - 0.0043 16.7 0.2 0.034 13.8 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EWM23144.1 - 0.015 14.8 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EWM23144.1 - 0.017 15.2 0.0 0.2 11.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EWM23144.1 - 0.069 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 EWM23144.1 - 0.12 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Mito_carr PF00153.22 EWM23145.1 - 3.1e-52 174.2 0.4 1.6e-20 72.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.22 EWM23146.1 - 4.6e-52 173.7 0.4 1.5e-20 72.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein La PF05383.12 EWM23147.1 - 3e-12 46.1 0.0 5.5e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 La domain Lipase_3 PF01764.20 EWM23148.1 - 2.3e-06 27.2 0.0 5.5e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EWM23148.1 - 0.0017 18.2 0.0 0.0058 16.5 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.7 EWM23148.1 - 0.081 12.6 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.2 EWM23148.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF4131 PF13567.1 EWM23148.1 - 4 6.8 8.9 0.15 11.4 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF2838 PF10998.3 EWM23149.1 - 2.4e-31 107.8 8.3 2.4e-31 107.8 5.8 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Utp11 PF03998.8 EWM23150.1 - 0.0092 15.8 2.2 0.014 15.2 1.5 1.2 1 0 0 1 1 1 1 Utp11 protein SlyX PF04102.7 EWM23150.1 - 0.083 13.2 3.8 0.15 12.4 0.6 2.8 1 1 1 2 2 2 0 SlyX GAS PF13851.1 EWM23150.1 - 0.2 10.8 5.1 0.26 10.4 3.1 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding SOR_SNZ PF01680.12 EWM23151.1 - 2.7e-111 370.1 9.9 2.7e-111 370.1 6.9 1.5 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.9 EWM23151.1 - 8.4e-08 31.5 6.2 1.2e-06 27.8 0.1 2.7 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 EWM23151.1 - 0.00023 20.5 0.8 0.02 14.1 0.0 2.5 3 0 0 3 3 3 2 Histidine biosynthesis protein Dus PF01207.12 EWM23151.1 - 0.0044 15.8 0.6 2.2 7.0 0.2 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NMO PF03060.10 EWM23151.1 - 0.0052 15.9 0.2 0.0052 15.9 0.1 2.1 2 0 0 2 2 2 1 Nitronate monooxygenase IGPS PF00218.16 EWM23151.1 - 0.012 14.6 0.4 0.051 12.6 0.0 2.1 3 0 0 3 3 3 0 Indole-3-glycerol phosphate synthase NanE PF04131.9 EWM23151.1 - 0.032 13.1 2.0 0.12 11.3 0.0 2.5 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase SOR_SNZ PF01680.12 EWM23152.1 - 1.1e-90 302.8 3.8 1.1e-90 302.8 2.6 1.6 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.9 EWM23152.1 - 1.1e-07 31.2 2.8 8.3e-07 28.3 0.1 2.7 2 1 2 4 4 4 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 EWM23152.1 - 0.00022 20.5 0.1 0.014 14.6 0.0 2.5 3 0 0 3 3 3 1 Histidine biosynthesis protein NMO PF03060.10 EWM23152.1 - 0.0014 17.8 1.2 0.0036 16.5 0.1 1.9 2 0 0 2 2 2 1 Nitronate monooxygenase Dus PF01207.12 EWM23152.1 - 0.0052 15.6 0.1 1.6 7.5 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.9 EWM23152.1 - 0.0082 15.1 0.3 0.088 11.7 0.0 2.4 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.16 EWM23152.1 - 0.017 14.1 0.0 0.037 13.0 0.0 1.5 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase TMP-TENI PF02581.12 EWM23152.1 - 0.22 10.6 1.9 1.6 7.7 0.1 2.9 3 1 0 3 3 3 0 Thiamine monophosphate synthase/TENI COesterase PF00135.23 EWM23154.1 - 6.9e-104 348.4 0.0 9.1e-104 348.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EWM23154.1 - 2.3e-09 37.1 0.3 6.1e-09 35.7 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EWM23154.1 - 0.00011 21.5 0.3 0.00022 20.5 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EWM23154.1 - 0.00025 20.8 0.1 0.0004 20.1 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family GCV_T PF01571.16 EWM23155.1 - 1.8e-25 89.5 0.0 2.8e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EWM23155.1 - 1.4e-06 28.2 0.1 1.2e-05 25.2 0.1 2.3 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain DUF3827 PF12877.2 EWM23156.1 - 0.42 8.6 5.2 0.58 8.1 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF390 PF04094.9 EWM23156.1 - 0.44 8.5 7.7 0.62 8.0 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) SR-25 PF10500.4 EWM23156.1 - 1.7 8.0 13.7 2.7 7.4 9.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF390 PF04094.9 EWM23157.1 - 0.41 8.6 7.6 0.58 8.1 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) DUF3827 PF12877.2 EWM23157.1 - 0.45 8.5 5.2 0.62 8.1 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) SR-25 PF10500.4 EWM23157.1 - 1.9 7.8 13.7 2.8 7.3 9.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NPV_P10 PF05531.7 EWM23158.1 - 0.0033 17.6 1.7 3.1 8.1 0.2 3.1 2 1 1 3 3 3 2 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.1 EWM23158.1 - 0.0066 14.9 3.1 0.013 14.0 2.2 1.6 1 0 0 1 1 1 1 AAA domain Baculo_PEP_C PF04513.7 EWM23158.1 - 0.016 15.0 2.0 0.77 9.5 0.5 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Med21 PF11221.3 EWM23158.1 - 0.5 10.3 0.1 0.5 10.3 0.0 4.3 3 1 1 4 4 4 0 Subunit 21 of Mediator complex DUF1664 PF07889.7 EWM23158.1 - 0.62 9.8 12.9 12 5.6 0.1 4.1 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.4 EWM23158.1 - 1 9.5 11.3 31 4.7 0.2 4.3 2 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ADIP PF11559.3 EWM23158.1 - 1.4 8.8 20.2 0.62 9.9 0.2 3.4 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding GP41 PF00517.12 EWM23158.1 - 2.8 7.4 10.1 3.4 7.1 0.1 3.3 3 1 0 4 4 4 0 Retroviral envelope protein DUF2317 PF10079.4 EWM23158.1 - 9.3 4.7 20.0 0.22 10.1 4.9 2.9 2 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2317) Aldo_ket_red PF00248.16 EWM23159.1 - 1e-36 126.2 0.0 1.2e-36 125.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family RRM_6 PF14259.1 EWM23160.1 - 9e-20 70.4 0.0 1.4e-13 50.5 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EWM23160.1 - 2.9e-11 42.8 0.0 9.9e-09 34.7 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM23160.1 - 0.0056 16.4 0.0 0.041 13.7 0.0 2.4 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) p450 PF00067.17 EWM23162.1 - 1.2e-56 192.2 0.0 1.7e-56 191.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_16 PF10294.4 EWM23163.1 - 4.3e-23 81.6 0.0 6.2e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Ank_2 PF12796.2 EWM23163.1 - 1.4e-18 66.9 0.1 1.7e-17 63.5 0.1 2.5 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EWM23163.1 - 2.8e-17 62.7 1.7 1.6e-13 50.7 0.2 3.2 3 1 2 5 5 4 2 Ankyrin repeats (many copies) Ank PF00023.25 EWM23163.1 - 7.1e-17 60.2 1.5 1.3e-07 31.0 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EWM23163.1 - 1.2e-13 50.7 3.2 5.5e-06 26.4 0.2 4.1 3 1 2 5 5 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM23163.1 - 6.2e-13 47.6 1.1 7.7e-05 22.5 0.0 4.1 5 0 0 5 5 4 2 Ankyrin repeat Methyltransf_26 PF13659.1 EWM23163.1 - 7.6e-06 25.9 0.7 2e-05 24.6 0.5 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EWM23163.1 - 2.5e-05 23.7 0.3 7.3e-05 22.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EWM23163.1 - 3.2e-05 24.4 0.0 7.4e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM23163.1 - 0.014 15.8 0.0 0.032 14.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EWM23163.1 - 0.021 15.2 0.0 0.043 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EWM23163.1 - 0.049 13.2 0.0 0.12 11.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EWM23163.1 - 0.058 12.5 0.0 0.094 11.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CUT PF02376.10 EWM23163.1 - 0.06 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 CUT domain SSrecog PF03531.9 EWM23164.1 - 5.9e-51 172.9 0.1 1.2e-50 171.9 0.0 1.5 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EWM23164.1 - 8e-24 83.4 0.0 9.6e-23 79.9 0.0 2.8 3 0 0 3 3 3 1 Histone chaperone Rttp106-like HMG_box PF00505.14 EWM23164.1 - 7.9e-22 77.3 0.6 7.9e-22 77.3 0.4 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EWM23164.1 - 1.6e-15 57.1 1.2 1.6e-15 57.1 0.8 2.0 2 0 0 2 2 2 1 HMG-box domain YbaB_DNA_bd PF02575.11 EWM23166.1 - 1.9e-06 27.6 0.7 3.7e-06 26.7 0.5 1.5 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family Gemini_AC4_5 PF04807.7 EWM23166.1 - 0.2 11.1 0.2 0.38 10.2 0.2 1.5 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region Complex1_LYR PF05347.10 EWM23167.1 - 5.6e-06 26.0 0.3 1.1e-05 25.1 0.2 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EWM23167.1 - 5.2e-05 23.3 0.3 9.8e-05 22.4 0.1 1.5 2 0 0 2 2 2 1 Complex1_LYR-like CD36 PF01130.16 EWM23168.1 - 4.4e-46 157.1 0.0 1.6e-22 79.4 0.0 2.5 2 1 0 2 2 2 2 CD36 family Aldo_ket_red PF00248.16 EWM23169.1 - 2.3e-36 125.0 0.0 2.8e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family JAB PF01398.16 EWM23171.1 - 0.028 14.1 0.1 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CRAL_TRIO PF00650.15 EWM23172.1 - 8.5e-23 80.5 0.0 1.2e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EWM23172.1 - 6.5e-10 39.1 0.0 9.9e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Tropomyosin_1 PF12718.2 EWM23173.1 - 3.4 7.5 25.8 5.7 6.7 17.9 1.4 1 0 0 1 1 1 0 Tropomyosin like V_ATPase_I PF01496.14 EWM23173.1 - 5.1 4.8 12.3 4.8 4.9 8.0 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family ApoO PF09769.4 EWM23173.1 - 8.7 6.0 7.5 1.1 8.9 1.5 1.9 1 1 1 2 2 2 0 Apolipoprotein O YbaB_DNA_bd PF02575.11 EWM23174.1 - 2.4e-12 46.5 2.0 3.7e-12 45.9 1.4 1.3 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family WSS_VP PF12175.3 EWM23174.1 - 0.033 13.2 0.1 0.18 10.8 0.0 1.9 2 0 0 2 2 2 0 White spot syndrome virus structural envelope protein VP PP2C PF00481.16 EWM23175.1 - 4e-57 193.5 0.0 5.8e-57 192.9 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Exo_endo_phos PF03372.18 EWM23176.1 - 7.1e-24 85.0 0.0 1e-23 84.6 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EWM23176.1 - 1.9e-05 24.2 0.0 3.7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Lactonase PF10282.4 EWM23177.1 - 2.9e-13 49.6 0.0 4.7e-06 25.9 0.0 4.0 1 1 3 4 4 4 4 Lactonase, 7-bladed beta-propeller PQQ_3 PF13570.1 EWM23177.1 - 0.069 13.4 3.5 4.7 7.6 0.0 4.2 4 1 0 4 4 4 0 PQQ-like domain SGL PF08450.7 EWM23177.1 - 0.086 12.1 0.0 49 3.1 0.0 3.6 2 1 1 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region YgbB PF02542.11 EWM23179.1 - 1.8e-57 193.5 0.0 2.2e-57 193.2 0.0 1.1 1 0 0 1 1 1 1 YgbB family F1F0-ATPsyn_F PF10791.4 EWM23180.1 - 0.02 15.1 0.4 0.025 14.8 0.3 1.2 1 0 0 1 1 1 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi PAP_central PF04928.12 EWM23181.1 - 1.8e-69 233.3 0.0 2.4e-69 232.9 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain NTP_transf_2 PF01909.18 EWM23181.1 - 0.0008 19.6 0.0 0.0015 18.8 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Metallophos_2 PF12850.2 EWM23182.1 - 7.2e-21 74.6 0.0 8.9e-21 74.3 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EWM23182.1 - 7.1e-05 22.2 0.3 0.024 14.0 0.1 2.1 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase PPR_2 PF13041.1 EWM23184.1 - 6.3e-53 176.5 0.0 1.9e-14 53.3 0.0 9.8 7 3 3 11 11 11 8 PPR repeat family PPR_3 PF13812.1 EWM23184.1 - 1.8e-36 121.3 16.2 2.8e-05 24.0 0.0 11.4 11 1 1 12 12 12 7 Pentatricopeptide repeat domain PPR PF01535.15 EWM23184.1 - 5.7e-35 116.8 15.5 7.3e-06 25.6 0.0 11.8 13 1 0 13 13 13 8 PPR repeat PPR_1 PF12854.2 EWM23184.1 - 1.3e-31 107.7 1.0 2.9e-05 23.4 0.0 10.0 11 0 0 11 11 11 5 PPR repeat TPR_19 PF14559.1 EWM23184.1 - 0.00057 20.1 6.5 1.4 9.3 0.0 5.1 6 1 1 7 7 7 2 Tetratricopeptide repeat BTAD PF03704.12 EWM23184.1 - 0.0016 18.7 5.7 2.2 8.5 0.1 4.1 3 1 0 3 3 3 1 Bacterial transcriptional activator domain TPR_16 PF13432.1 EWM23184.1 - 0.002 18.7 7.5 1.6 9.4 0.1 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 EWM23184.1 - 0.0058 17.1 20.8 0.25 12.0 0.0 7.3 8 1 1 9 9 7 1 Tetratricopeptide repeat Apc3 PF12895.2 EWM23184.1 - 0.029 14.4 0.1 3.9 7.6 0.1 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Clathrin PF00637.15 EWM23184.1 - 0.065 12.8 0.0 1.2 8.7 0.0 2.9 3 0 0 3 3 3 0 Region in Clathrin and VPS TPR_6 PF13174.1 EWM23184.1 - 0.22 12.0 1.5 21 5.8 0.2 4.3 5 0 0 5 5 3 0 Tetratricopeptide repeat Lipase_GDSL PF00657.17 EWM23185.1 - 2.3e-10 40.6 0.0 1.3e-09 38.2 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EWM23185.1 - 2.8e-10 40.6 0.0 3.8e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Patatin PF01734.17 EWM23186.1 - 1.8e-11 44.3 3.1 1.4e-10 41.4 1.6 2.1 2 0 0 2 2 2 1 Patatin-like phospholipase PADR1 PF08063.7 EWM23186.1 - 0.13 11.6 0.8 0.22 10.9 0.5 1.3 1 0 0 1 1 1 0 PADR1 (NUC008) domain DAGAT PF03982.8 EWM23187.1 - 4.6e-44 150.2 0.0 6e-44 149.9 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.16 EWM23187.1 - 0.077 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Acyltransferase Med3 PF11593.3 EWM23190.1 - 0.017 14.3 0.5 0.017 14.3 0.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Synaptobrevin PF00957.16 EWM23191.1 - 1.8e-13 49.8 0.1 3.3e-13 49.0 0.1 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EWM23191.1 - 6.1e-12 44.9 0.0 1.3e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain KH_1 PF00013.24 EWM23192.1 - 1.7e-06 27.5 0.2 3.2e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 KH domain Steroid_dh PF02544.11 EWM23193.1 - 5.5e-22 78.1 0.1 8.7e-22 77.5 0.1 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 EWM23193.1 - 0.0023 18.0 0.2 0.0044 17.1 0.1 1.5 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.7 EWM23193.1 - 0.003 16.8 0.1 0.0047 16.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) FGGY_N PF00370.16 EWM23194.1 - 1.8e-06 27.4 0.1 0.0025 17.1 0.0 2.4 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Yae1_N PF09811.4 EWM23197.1 - 0.34 10.4 9.3 24 4.5 6.0 2.6 1 1 0 1 1 1 0 Essential protein Yae1, N terminal DUF1777 PF08648.7 EWM23197.1 - 0.74 9.5 33.9 1.2 8.7 23.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Ras PF00071.17 EWM23199.1 - 1.6e-38 131.6 0.0 2e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EWM23199.1 - 4.9e-16 59.2 0.0 6.4e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EWM23199.1 - 8.3e-09 34.9 0.0 1.1e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EWM23199.1 - 0.00018 21.4 0.0 0.00024 21.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EWM23199.1 - 0.0016 17.6 0.0 0.0019 17.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 EWM23199.1 - 0.013 14.7 0.0 0.023 13.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EWM23199.1 - 0.037 14.1 0.0 0.059 13.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EWM23199.1 - 0.13 12.2 0.1 0.2 11.6 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.1 EWM23199.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.3 1 1 0 1 1 1 0 AAA domain FAD_binding_6 PF00970.19 EWM23202.1 - 6.1e-14 51.9 0.0 9.6e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EWM23202.1 - 1.5e-12 48.0 0.0 2.2e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EWM23202.1 - 0.00014 21.8 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Zn_clus PF00172.13 EWM23204.1 - 3e-09 36.6 7.1 5.3e-09 35.8 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 EWM23205.1 - 2.8e-06 27.1 14.3 6.5e-06 25.9 9.9 1.7 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LEA_5 PF00477.12 EWM23207.1 - 0.59 10.4 11.7 0.8 10.0 8.1 1.1 1 0 0 1 1 1 0 Small hydrophilic plant seed protein Chloroa_b-bind PF00504.16 EWM23208.1 - 1.9e-14 54.2 0.0 2.4e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein EXS PF03124.9 EWM23211.1 - 4.3e-08 32.5 0.3 4.7e-08 32.4 0.2 1.1 1 0 0 1 1 1 1 EXS family DUF3432 PF11914.3 EWM23211.1 - 1.8 8.6 5.6 3 7.9 3.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3432) FA_desaturase PF00487.19 EWM23212.1 - 1.6e-09 37.5 0.1 2.1e-09 37.2 0.1 1.1 1 0 0 1 1 1 1 Fatty acid desaturase TUG-UBL1 PF11470.3 EWM23212.1 - 0.039 13.8 0.0 0.057 13.3 0.0 1.2 1 0 0 1 1 1 0 GLUT4 regulating protein TUG DUF2953 PF11167.3 EWM23217.1 - 0.14 12.0 0.1 0.28 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) ATP_bind_4 PF01902.12 EWM23218.1 - 4.6e-12 45.7 0.1 5.5e-06 25.8 0.0 2.1 2 0 0 2 2 2 2 ATP-binding region DUF1045 PF06299.7 EWM23218.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) ABC1 PF03109.11 EWM23221.1 - 6.2e-06 26.1 0.1 6.7e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 ABC1 family Beta-lactamase PF00144.19 EWM23222.1 - 5.2e-13 48.7 0.1 5.9e-13 48.5 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF1611 PF07755.6 EWM23223.1 - 0.05 12.2 0.0 0.068 11.8 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1611) DUF2583 PF10762.4 EWM23224.1 - 0.48 10.6 3.1 0.61 10.2 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2583) XG_FTase PF03254.8 EWM23227.1 - 0.00012 20.7 0.2 0.014 13.9 0.1 2.8 2 1 0 2 2 2 2 Xyloglucan fucosyltransferase Glyco_transf_11 PF01531.11 EWM23227.1 - 0.061 12.3 0.1 2.8 6.8 0.0 2.2 1 1 1 2 2 2 0 Glycosyl transferase family 11 Peptidase_S8 PF00082.17 EWM23228.1 - 9.6e-35 120.0 3.4 1.5e-34 119.4 2.3 1.2 1 0 0 1 1 1 1 Subtilase family HEAT_2 PF13646.1 EWM23231.1 - 1.9e-09 37.7 1.6 0.0035 17.5 0.2 4.2 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.17 EWM23231.1 - 1.6e-06 27.7 9.4 0.39 10.9 0.0 5.8 7 0 0 7 7 7 4 HEAT repeat HEAT_EZ PF13513.1 EWM23231.1 - 0.0076 16.7 16.0 0.24 11.9 0.1 5.8 6 1 1 7 7 7 2 HEAT-like repeat Chloroa_b-bind PF00504.16 EWM23233.1 - 2.2e-18 67.0 0.0 3.1e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Fasciclin PF02469.17 EWM23234.1 - 1.6e-37 128.3 0.2 2e-37 128.0 0.1 1.1 1 0 0 1 1 1 1 Fasciclin domain SHMT PF00464.14 EWM23234.1 - 0.048 12.0 0.3 0.067 11.5 0.2 1.1 1 0 0 1 1 1 0 Serine hydroxymethyltransferase HrcA_DNA-bdg PF03444.10 EWM23234.1 - 0.048 13.0 0.0 0.13 11.6 0.0 1.7 2 0 0 2 2 2 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding NUC202 PF08166.7 EWM23234.1 - 0.073 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 NUC202 domain Glyco_transf_92 PF01697.22 EWM23238.1 - 1.1e-11 44.5 0.0 1.7e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.1 EWM23238.1 - 0.0026 18.0 0.0 0.012 15.8 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 2 Thyroglobulin_1 PF00086.13 EWM23238.1 - 0.065 12.5 0.3 0.15 11.4 0.2 1.5 1 0 0 1 1 1 0 Thyroglobulin type-1 repeat Pyrophosphatase PF00719.14 EWM23239.1 - 8.3e-33 113.0 0.1 1.1e-32 112.6 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase SR-25 PF10500.4 EWM23240.1 - 0.69 9.3 4.2 0.86 9.0 2.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein adh_short PF00106.20 EWM23241.1 - 8.1e-10 38.8 2.4 5.9e-09 36.0 1.7 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EWM23241.1 - 0.00052 19.8 0.0 0.00072 19.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.14 EWM23241.1 - 0.018 14.0 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain KR PF08659.5 EWM23241.1 - 0.019 14.6 0.3 0.038 13.6 0.2 1.4 1 1 0 1 1 1 0 KR domain Eno-Rase_NADH_b PF12242.3 EWM23241.1 - 0.052 13.3 0.1 0.2 11.4 0.2 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase SR-25 PF10500.4 EWM23242.1 - 0.3 10.5 4.3 0.46 9.9 2.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Methyltransf_22 PF13383.1 EWM23245.1 - 1e-75 254.4 0.0 1.2e-75 254.1 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.7 EWM23245.1 - 3.4e-06 27.1 0.0 5.7e-06 26.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase FkbM domain Tetraspannin PF00335.15 EWM23245.1 - 0.035 13.3 0.1 1.5 8.0 0.0 2.2 1 1 1 2 2 2 0 Tetraspanin family Methyltransf_22 PF13383.1 EWM23246.1 - 2.5e-77 259.7 0.1 2.9e-77 259.5 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.7 EWM23246.1 - 3.1e-06 27.2 0.0 5.1e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase FkbM domain Tetraspannin PF00335.15 EWM23246.1 - 0.056 12.7 0.3 1.4 8.1 0.0 2.3 1 1 0 2 2 2 0 Tetraspanin family HhH-GPD PF00730.20 EWM23247.1 - 7.8e-12 45.4 0.0 1.4e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Se-cys_synth_N PF12390.3 EWM23247.1 - 0.027 14.5 0.5 0.055 13.5 0.3 1.5 1 0 0 1 1 1 0 Selenocysteine synthase N terminal Vac14_Fab1_bd PF12755.2 EWM23248.1 - 0.012 15.9 0.4 0.022 15.1 0.1 1.5 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region bZIP_2 PF07716.10 EWM23248.1 - 0.051 13.4 0.7 0.075 12.8 0.5 1.3 1 0 0 1 1 1 0 Basic region leucine zipper Cut8_N PF14482.1 EWM23248.1 - 0.14 12.1 1.0 0.25 11.3 0.7 1.5 1 0 0 1 1 1 0 Cut8 proteasome-binding domain BSP_II PF05432.6 EWM23259.1 - 0.039 13.2 15.4 0.043 13.1 10.7 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) FAM176 PF14851.1 EWM23259.1 - 0.086 12.5 2.4 0.1 12.2 1.6 1.1 1 0 0 1 1 1 0 FAM176 family Nucleoplasmin PF03066.10 EWM23259.1 - 0.39 10.2 11.7 0.48 9.9 8.1 1.1 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 EWM23259.1 - 0.41 9.8 4.0 0.4 9.8 2.8 1.1 1 0 0 1 1 1 0 NOA36 protein PAXIP1_C PF15364.1 EWM23259.1 - 0.89 9.4 6.4 1 9.2 4.5 1.1 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein PBP1_TM PF14812.1 EWM23259.1 - 1.3 9.4 7.3 1.7 8.9 5.0 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Myc_N PF01056.13 EWM23259.1 - 1.3 8.1 7.9 1.3 8.1 5.5 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Radial_spoke PF04712.7 EWM23259.1 - 1.5 7.4 11.5 1.5 7.4 8.0 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein SHR3_chaperone PF08229.6 EWM23259.1 - 1.7 7.5 3.6 2.1 7.2 2.5 1.0 1 0 0 1 1 1 0 ER membrane protein SH3 Pox_Ag35 PF03286.9 EWM23259.1 - 1.8 8.0 6.5 1.7 8.1 4.5 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.9 EWM23259.1 - 3 5.7 6.9 2.7 5.9 4.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Adeno_terminal PF02459.10 EWM23259.1 - 5.4 5.0 6.4 5.5 5.0 4.5 1.0 1 0 0 1 1 1 0 Adenoviral DNA terminal protein TRAP_alpha PF03896.11 EWM23259.1 - 7.3 5.5 6.3 8 5.3 4.4 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Smr PF01713.16 EWM23260.1 - 0.00058 19.9 0.0 0.0069 16.5 0.0 2.6 2 1 0 2 2 2 1 Smr domain DUF3446 PF11928.3 EWM23260.1 - 1 9.6 13.3 1.7 8.9 5.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) ABC_tran PF00005.22 EWM23265.1 - 1.7e-08 34.8 0.1 2.6e-08 34.2 0.1 1.2 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 EWM23265.1 - 0.0012 18.0 0.4 0.0015 17.7 0.0 1.4 2 0 0 2 2 1 1 Protein of unknown function, DUF258 Rad17 PF03215.10 EWM23265.1 - 0.0033 16.1 0.1 0.004 15.8 0.1 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_25 PF13481.1 EWM23265.1 - 0.0039 16.6 0.0 0.0049 16.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EWM23265.1 - 0.016 16.0 0.1 0.033 14.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EWM23265.1 - 0.018 15.0 0.1 0.024 14.6 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.1 EWM23265.1 - 0.022 14.7 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EWM23265.1 - 0.03 14.2 0.1 0.043 13.7 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EWM23265.1 - 0.032 14.3 0.0 0.061 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EWM23265.1 - 0.045 14.0 0.1 0.066 13.5 0.1 1.3 1 1 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 EWM23265.1 - 0.047 13.1 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.1 EWM23265.1 - 0.065 13.5 0.5 0.16 12.2 0.3 1.7 2 0 0 2 2 2 0 AAA domain AAA_35 PF14516.1 EWM23265.1 - 0.085 11.4 0.0 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain AAA_29 PF13555.1 EWM23265.1 - 0.089 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 EWM23265.1 - 0.089 12.4 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 EWM23265.1 - 0.098 12.5 0.0 0.19 11.6 0.0 1.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EWM23265.1 - 0.13 11.7 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein PRK PF00485.13 EWM23265.1 - 0.13 11.8 0.1 0.42 10.1 0.0 1.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA PF00004.24 EWM23265.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.1 EWM23265.1 - 0.15 11.0 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Isy1 PF06246.7 EWM23267.1 - 7e-90 300.8 7.0 7.9e-90 300.6 4.8 1.0 1 0 0 1 1 1 1 Isy1-like splicing family zf-H2C2 PF09337.5 EWM23267.1 - 0.13 11.6 0.4 0.4 10.1 0.3 1.8 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger ScpA_ScpB PF02616.9 EWM23267.1 - 2.6 7.5 8.0 9.5 5.7 2.7 2.2 2 0 0 2 2 2 0 ScpA/B protein PUF PF00806.14 EWM23275.1 - 2.9e-35 117.7 1.8 2.8e-09 35.9 0.0 4.3 4 0 0 4 4 4 4 Pumilio-family RNA binding repeat HNOB PF07700.10 EWM23275.1 - 0.019 14.4 0.2 3.3 7.1 0.1 2.4 1 1 1 2 2 2 0 Heme NO binding TFIID-31kDa PF02291.10 EWM23275.1 - 0.021 14.6 0.2 0.066 13.0 0.1 1.8 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit DUF4350 PF14258.1 EWM23275.1 - 0.089 13.0 0.0 1.2 9.4 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4350) HAD PF12710.2 EWM23277.1 - 3.2e-06 27.4 0.0 1.6e-05 25.1 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase CENP-B_dimeris PF09026.5 EWM23277.1 - 0.15 12.3 10.5 0.32 11.2 7.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FLO_LFY PF01698.11 EWM23277.1 - 0.24 10.1 6.5 0.34 9.7 4.5 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein RNA_pol_3_Rpc31 PF11705.3 EWM23277.1 - 0.55 10.1 12.6 0.81 9.5 8.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nucleo_P87 PF07267.6 EWM23277.1 - 0.66 8.5 4.5 0.89 8.1 3.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DDHD PF02862.12 EWM23277.1 - 0.66 9.7 5.2 1 9.1 3.6 1.2 1 0 0 1 1 1 0 DDHD domain BSP_II PF05432.6 EWM23277.1 - 0.99 8.6 18.5 2 7.6 12.8 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF3530 PF12048.3 EWM23277.1 - 1 8.3 4.3 1.9 7.3 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Pox_Ag35 PF03286.9 EWM23277.1 - 1.1 8.7 9.9 1.8 8.0 6.9 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PPP4R2 PF09184.6 EWM23277.1 - 1.2 8.5 15.2 1.7 8.1 10.5 1.1 1 0 0 1 1 1 0 PPP4R2 Myc_N PF01056.13 EWM23277.1 - 1.3 8.1 8.7 2.1 7.4 6.0 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Ribosomal_60s PF00428.14 EWM23277.1 - 1.3 9.5 15.1 3.9 7.9 10.4 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein Nucleoplasmin PF03066.10 EWM23277.1 - 1.3 8.5 13.0 2.4 7.6 9.0 1.4 1 0 0 1 1 1 0 Nucleoplasmin Radial_spoke PF04712.7 EWM23277.1 - 2.8 6.5 14.8 3.8 6.1 10.2 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Vfa1 PF08432.5 EWM23277.1 - 3.3 7.7 12.8 5.9 6.8 8.9 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PBP_sp32 PF07222.7 EWM23277.1 - 4.6 6.3 11.1 7.7 5.6 7.7 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 FAM176 PF14851.1 EWM23277.1 - 5.8 6.5 8.1 13 5.3 5.6 1.6 1 0 0 1 1 1 0 FAM176 family DUF1510 PF07423.6 EWM23277.1 - 6.6 6.0 14.7 1.8 7.8 8.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Daxx PF03344.10 EWM23277.1 - 6.8 5.0 14.2 9.4 4.5 9.9 1.1 1 0 0 1 1 1 0 Daxx Family Ank_2 PF12796.2 EWM23278.1 - 4.2e-11 43.0 0.0 5.5e-07 29.8 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EWM23278.1 - 1.6e-09 37.7 0.1 0.0049 17.0 0.1 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EWM23278.1 - 2.1e-07 30.3 0.3 1 9.3 0.1 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 EWM23278.1 - 1.4e-05 24.8 0.0 1.1 9.7 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EWM23278.1 - 4.5e-05 23.8 0.0 0.073 13.6 0.0 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Beach PF02138.13 EWM23279.1 - 4.1e-104 347.7 0.0 6.1e-104 347.2 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 EWM23279.1 - 3.9e-12 45.9 0.0 2.2e-11 43.5 0.0 2.2 3 0 0 3 3 3 1 PH domain associated with Beige/BEACH FUN14 PF04930.10 EWM23280.1 - 8.7e-19 67.6 0.9 1.2e-18 67.2 0.6 1.2 1 0 0 1 1 1 1 FUN14 family SLX9 PF15341.1 EWM23281.1 - 3.7e-10 40.2 5.7 7e-10 39.3 2.5 2.1 1 1 1 2 2 2 1 Ribosome biogenesis protein SLX9 Aminotran_4 PF01063.14 EWM23282.1 - 1.9e-25 89.7 0.0 2.6e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Thioredoxin_8 PF13905.1 EWM23283.1 - 5.4e-24 84.1 0.0 9.3e-24 83.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like fn3 PF00041.16 EWM23283.1 - 5e-09 36.1 0.0 5.9e-05 23.1 0.0 3.0 2 1 0 2 2 2 2 Fibronectin type III domain Thioredoxin PF00085.15 EWM23283.1 - 1.2e-05 24.8 0.0 0.0002 20.9 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 EWM23283.1 - 5.7e-05 23.2 0.0 0.00014 22.0 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EWM23283.1 - 0.0012 18.5 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EWM23283.1 - 0.15 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Redoxin SCO1-SenC PF02630.9 EWM23283.1 - 0.17 11.4 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 SCO1/SenC Dymeclin PF09742.4 EWM23284.1 - 2e-45 155.1 0.0 9.9e-45 152.8 0.0 1.9 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein IncA PF04156.9 EWM23286.1 - 0.31 10.6 0.2 0.48 9.9 0.2 1.2 1 0 0 1 1 1 0 IncA protein Ribosomal_S7e PF01251.13 EWM23287.1 - 1.8e-77 259.1 3.7 2.1e-77 258.8 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e DHBP_synthase PF00926.14 EWM23288.1 - 5.1e-81 270.5 0.1 9.6e-81 269.6 0.1 1.5 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase GTP_cyclohydro2 PF00925.15 EWM23288.1 - 5.1e-52 175.5 0.0 1.1e-51 174.4 0.0 1.5 1 0 0 1 1 1 1 GTP cyclohydrolase II DUF605 PF04652.11 EWM23288.1 - 5.5 6.2 13.6 13 5.1 9.5 1.6 1 0 0 1 1 1 0 Vta1 like LRR_6 PF13516.1 EWM23289.1 - 3.1e-22 76.0 16.1 0.12 12.5 0.0 14.8 16 0 0 16 16 16 5 Leucine Rich repeat LRR_1 PF00560.28 EWM23289.1 - 1.9e-10 39.2 14.2 4.7 7.6 0.0 12.2 13 1 1 14 14 14 3 Leucine Rich Repeat LRR_4 PF12799.2 EWM23289.1 - 1.2e-08 34.3 13.0 5.6 6.7 0.2 10.0 10 3 1 11 11 11 4 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EWM23289.1 - 3.7e-07 29.2 21.5 17 6.1 0.0 12.9 15 0 0 15 15 15 2 Leucine rich repeat LRR_8 PF13855.1 EWM23289.1 - 5.6e-06 26.0 23.3 0.47 10.2 0.2 11.1 10 2 3 13 13 13 4 Leucine rich repeat Pet191_N PF10203.4 EWM23290.1 - 3.4e-17 62.2 4.7 3.8e-17 62.0 3.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CLP_protease PF00574.18 EWM23292.1 - 8.5e-30 103.7 0.0 1.2e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 Clp protease DUF3624 PF12292.3 EWM23292.1 - 0.52 10.7 2.4 0.65 10.4 1.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3624) AMP-binding PF00501.23 EWM23293.1 - 4.5e-22 78.0 0.1 5.6e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme BTB PF00651.26 EWM23294.1 - 1.8e-09 37.5 0.0 3.5e-09 36.6 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain F-box-like PF12937.2 EWM23296.1 - 0.0019 17.8 0.1 0.005 16.5 0.1 1.8 1 0 0 1 1 1 1 F-box-like Cmc1 PF08583.5 EWM23297.1 - 3.6e-16 58.6 2.8 4.7e-16 58.3 1.9 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 EWM23297.1 - 0.024 14.5 2.9 0.092 12.6 1.4 2.1 1 1 1 2 2 2 0 CHCH domain COX17 PF05051.8 EWM23297.1 - 0.048 13.6 1.4 0.35 10.9 0.1 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) NDUF_B7 PF05676.8 EWM23297.1 - 0.093 12.1 1.2 0.13 11.6 0.8 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) DUF3054 PF11255.3 EWM23298.1 - 1.3e-26 92.6 7.7 2.3e-26 91.8 5.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3054) CoA_binding_3 PF13727.1 EWM23298.1 - 0.0064 16.3 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 CoA-binding domain FlxA PF14282.1 EWM23298.1 - 0.062 13.2 0.2 0.091 12.7 0.1 1.1 1 0 0 1 1 1 0 FlxA-like protein AMP-binding PF00501.23 EWM23300.1 - 8.4e-61 205.5 0.0 1.1e-60 205.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme EamA PF00892.15 EWM23301.1 - 8.9e-22 77.4 22.8 1.4e-14 54.2 4.3 2.3 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EWM23301.1 - 1.5e-07 31.5 24.2 1.4e-05 25.2 2.6 3.0 2 1 1 3 3 3 2 Multidrug resistance efflux transporter Phtf-FEM1B_bdg PF12129.3 EWM23301.1 - 0.035 13.4 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor Peptidase_M50 PF02163.17 EWM23303.1 - 2.3e-09 36.4 12.7 8.9e-07 28.0 3.2 2.8 1 1 1 2 2 2 2 Peptidase family M50 Peptidase_M50B PF13398.1 EWM23303.1 - 0.00012 21.5 5.0 0.00012 21.5 3.5 2.5 1 1 1 2 2 2 1 Peptidase M50B-like Peptidase_M64 PF09471.5 EWM23303.1 - 0.13 11.9 0.1 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 IgA Peptidase M64 SNARE_assoc PF09335.6 EWM23305.1 - 5.4e-09 36.2 3.6 5.4e-09 36.2 2.5 2.5 2 1 1 3 3 3 1 SNARE associated Golgi protein SieB PF14163.1 EWM23305.1 - 0.087 12.3 0.1 1.3 8.6 0.0 2.3 2 1 0 2 2 2 0 Superinfection exclusion protein B COX8 PF02285.10 EWM23305.1 - 0.37 10.3 1.7 1.8 8.1 0.2 2.4 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIII Gemini_mov PF01708.11 EWM23305.1 - 0.4 10.2 2.7 4.8 6.8 0.3 3.0 3 0 0 3 3 3 0 Geminivirus putative movement protein RseC_MucC PF04246.7 EWM23305.1 - 0.41 10.2 4.8 7.3 6.1 0.0 2.8 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC MatE PF01554.13 EWM23306.1 - 9.4e-56 187.9 24.6 1.3e-33 115.9 3.5 2.5 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.1 EWM23306.1 - 1.2e-08 34.8 12.6 4.8e-07 29.6 2.1 3.7 5 0 0 5 5 5 2 Polysaccharide biosynthesis C-terminal domain Cupin_8 PF13621.1 EWM23307.1 - 1.1e-49 169.1 0.0 1.8e-49 168.5 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EWM23307.1 - 1.4e-09 37.6 0.0 2.6e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.17 EWM23307.1 - 0.0054 16.9 0.0 0.015 15.5 0.0 1.7 2 0 0 2 2 2 1 JmjC domain, hydroxylase DUF1971 PF09313.6 EWM23307.1 - 0.04 13.6 0.0 0.086 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1971) Cupin_2 PF07883.6 EWM23307.1 - 0.075 12.5 0.0 0.54 9.8 0.0 2.4 3 0 0 3 3 3 0 Cupin domain MIF PF01187.13 EWM23308.1 - 3.8e-13 49.5 0.0 4.4e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.16 EWM23308.1 - 1e-06 28.2 0.0 0.0072 15.9 0.0 2.1 2 0 0 2 2 2 2 Tautomerase enzyme Tautomerase_2 PF14552.1 EWM23308.1 - 0.021 14.8 0.0 0.039 13.9 0.0 1.6 1 1 1 2 2 2 0 Tautomerase enzyme Peptidase_M17_N PF02789.12 EWM23308.1 - 0.025 14.3 0.3 0.041 13.6 0.2 1.5 1 1 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain Esterase_phd PF10503.4 EWM23308.1 - 0.16 11.2 1.2 0.18 11.0 0.8 1.1 1 0 0 1 1 1 0 Esterase PHB depolymerase MIF PF01187.13 EWM23309.1 - 3.8e-13 49.5 0.0 4.4e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.16 EWM23309.1 - 1e-06 28.2 0.0 0.0072 15.9 0.0 2.1 2 0 0 2 2 2 2 Tautomerase enzyme Tautomerase_2 PF14552.1 EWM23309.1 - 0.021 14.8 0.0 0.039 13.9 0.0 1.6 1 1 1 2 2 2 0 Tautomerase enzyme Peptidase_M17_N PF02789.12 EWM23309.1 - 0.025 14.3 0.3 0.041 13.6 0.2 1.5 1 1 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain Esterase_phd PF10503.4 EWM23309.1 - 0.16 11.2 1.2 0.18 11.0 0.8 1.1 1 0 0 1 1 1 0 Esterase PHB depolymerase PAE PF03283.8 EWM23310.1 - 2.4e-58 197.5 0.3 7.9e-49 166.2 0.4 2.5 2 1 0 2 2 2 2 Pectinacetylesterase Atg14 PF10186.4 EWM23311.1 - 3.6e-08 32.7 0.0 4.6e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Atg14 PF10186.4 EWM23312.1 - 3.7e-08 32.6 0.0 4.6e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Chalcone PF02431.10 EWM23313.1 - 1.2e-24 86.8 0.1 1.4e-24 86.5 0.0 1.0 1 0 0 1 1 1 1 Chalcone-flavanone isomerase DUF1415 PF07209.7 EWM23316.1 - 7.4e-46 156.0 0.0 9.6e-46 155.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1415) PPR_2 PF13041.1 EWM23318.1 - 1.4e-103 338.7 9.5 1.5e-12 47.2 0.0 10.5 1 1 9 10 10 10 10 PPR repeat family PPR_1 PF12854.2 EWM23318.1 - 3.9e-73 240.6 0.1 1.1e-09 37.5 0.0 11.5 12 0 0 12 12 12 10 PPR repeat PPR_3 PF13812.1 EWM23318.1 - 1.1e-72 234.3 15.5 7.7e-07 28.9 0.0 12.1 12 0 0 12 12 12 10 Pentatricopeptide repeat domain PPR PF01535.15 EWM23318.1 - 4.6e-70 226.8 16.9 4.6e-07 29.3 0.0 11.1 12 0 0 12 12 10 10 PPR repeat TPR_7 PF13176.1 EWM23318.1 - 1.1e-06 27.9 1.1 4.3 7.3 0.0 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat MRP-S27 PF10037.4 EWM23318.1 - 2.7e-06 26.5 0.0 0.13 11.1 0.0 4.1 3 1 1 5 5 5 2 Mitochondrial 28S ribosomal protein S27 TPR_12 PF13424.1 EWM23318.1 - 5.6e-06 26.2 10.0 0.019 14.8 0.1 6.0 3 1 4 7 7 7 2 Tetratricopeptide repeat Ank_2 PF12796.2 EWM23318.1 - 1.5e-05 25.2 0.6 0.037 14.3 0.1 4.3 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) TPR_14 PF13428.1 EWM23318.1 - 3.9e-05 23.9 21.9 9.3 7.1 0.0 9.3 6 2 5 11 11 11 0 Tetratricopeptide repeat Apc3 PF12895.2 EWM23318.1 - 8.1e-05 22.6 0.1 4.6 7.4 0.0 5.4 3 2 4 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EWM23318.1 - 0.00015 22.3 8.7 9.9 6.9 0.0 6.6 6 2 1 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.1 EWM23318.1 - 0.00038 20.7 5.3 0.86 9.9 0.2 5.9 4 2 3 7 7 7 1 Tetratricopeptide repeat ECSIT PF06239.6 EWM23318.1 - 0.00063 18.6 0.0 0.88 8.3 0.0 4.7 3 2 2 5 5 5 1 Evolutionarily conserved signalling intermediate in Toll pathway FAT PF02259.18 EWM23318.1 - 0.0043 16.0 0.1 1.4 7.8 0.0 3.3 2 1 0 3 3 3 1 FAT domain Ank_4 PF13637.1 EWM23318.1 - 0.0049 17.3 0.1 0.89 10.1 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) TPR_11 PF13414.1 EWM23318.1 - 0.032 13.8 3.4 8.5 6.1 0.0 4.7 5 0 0 5 5 5 0 TPR repeat Radical_SAM PF04055.16 EWM23318.1 - 0.078 13.1 0.0 3 8.0 0.0 2.9 1 1 0 2 2 2 0 Radical SAM superfamily Pyr_excise PF03013.9 EWM23318.1 - 0.21 11.3 0.2 33 4.2 0.0 4.1 5 1 1 6 6 6 0 Pyrimidine dimer DNA glycosylase TPR_2 PF07719.12 EWM23318.1 - 0.22 11.5 9.7 22 5.2 0.0 6.2 10 0 0 10 10 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 EWM23318.1 - 0.52 10.3 15.0 23 5.0 0.0 7.0 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 EWM23318.1 - 2.2 8.0 6.6 18 5.1 0.0 5.1 8 0 0 8 8 6 0 Tetratricopeptide repeat MR_MLE PF01188.16 EWM23318.1 - 2.2 8.8 6.4 7.1 7.2 0.1 4.0 3 1 1 4 4 3 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Cupin_4 PF08007.7 EWM23319.1 - 1.4e-16 60.6 0.1 1.5e-13 50.6 0.0 3.2 1 1 1 2 2 2 2 Cupin superfamily protein MMtag PF10159.4 EWM23320.1 - 2.9e-29 100.9 4.7 2.9e-29 100.9 3.3 2.7 2 1 0 2 2 2 1 Kinase phosphorylation protein Basic PF01586.11 EWM23320.1 - 0.27 11.9 0.0 0.27 11.9 0.0 3.4 3 1 1 4 4 4 0 Myogenic Basic domain Med19 PF10278.4 EWM23320.1 - 0.3 10.7 15.4 0.65 9.6 10.6 1.6 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 TATR PF03430.8 EWM23320.1 - 0.86 8.1 7.9 1.1 7.7 5.5 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Selenoprotein_S PF06936.6 EWM23320.1 - 1.9 7.9 18.4 0.32 10.4 8.9 2.3 2 0 0 2 2 2 0 Selenoprotein S (SelS) FRG2 PF15315.1 EWM23320.1 - 4.4 7.2 23.9 1.1 9.1 12.9 2.3 2 1 0 2 2 2 0 Facioscapulohumeral muscular dystrophy candidate 2 Peptidase_S49_N PF08496.5 EWM23320.1 - 6.7 6.4 11.1 14 5.4 7.7 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal MMtag PF10159.4 EWM23321.1 - 0.00088 19.2 0.6 0.00088 19.2 0.4 2.9 2 1 0 2 2 2 1 Kinase phosphorylation protein Med19 PF10278.4 EWM23321.1 - 0.11 12.1 14.9 0.24 11.0 10.3 1.6 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 TATR PF03430.8 EWM23321.1 - 0.36 9.3 7.6 0.46 9.0 5.3 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator CDC27 PF09507.5 EWM23321.1 - 0.93 8.6 19.8 0.12 11.5 11.0 1.4 1 1 0 1 1 1 0 DNA polymerase subunit Cdc27 Peptidase_S49_N PF08496.5 EWM23321.1 - 1.1 9.0 9.4 2.2 8.0 6.5 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal U79_P34 PF03064.11 EWM23321.1 - 1.5 8.2 18.2 3.2 7.2 12.6 1.6 1 0 0 1 1 1 0 HSV U79 / HCMV P34 FRG2 PF15315.1 EWM23321.1 - 3.7 7.4 25.1 0.45 10.4 12.5 2.4 2 1 1 3 3 3 0 Facioscapulohumeral muscular dystrophy candidate 2 DUF4551 PF15087.1 EWM23321.1 - 8.8 4.5 7.6 11 4.1 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) MMtag PF10159.4 EWM23322.1 - 2.9e-29 100.9 4.7 2.9e-29 100.9 3.3 2.7 2 1 0 2 2 2 1 Kinase phosphorylation protein Basic PF01586.11 EWM23322.1 - 0.26 12.0 0.0 0.26 12.0 0.0 3.4 3 1 0 3 3 3 0 Myogenic Basic domain Med19 PF10278.4 EWM23322.1 - 0.27 10.8 15.4 0.64 9.6 10.6 1.6 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 TATR PF03430.8 EWM23322.1 - 0.84 8.2 7.9 1.1 7.7 5.5 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Selenoprotein_S PF06936.6 EWM23322.1 - 2.2 7.7 18.4 0.32 10.5 8.9 2.1 2 0 0 2 2 2 0 Selenoprotein S (SelS) FRG2 PF15315.1 EWM23322.1 - 4.3 7.2 23.9 1.1 9.1 12.9 2.3 2 1 0 2 2 2 0 Facioscapulohumeral muscular dystrophy candidate 2 Peptidase_S49_N PF08496.5 EWM23322.1 - 6.7 6.4 11.1 14 5.4 7.7 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal ABC2_membrane PF01061.19 EWM23323.1 - 1.6e-27 96.0 22.0 2.4e-27 95.4 15.2 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EWM23323.1 - 1.6e-25 90.0 0.0 2.4e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EWM23323.1 - 1.7e-07 31.5 0.0 8.8e-05 22.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain ABC2_membrane_2 PF12679.2 EWM23323.1 - 2.2e-07 30.0 1.9 2.2e-07 30.0 1.3 2.1 1 1 1 2 2 2 1 ABC-2 family transporter protein SMC_N PF02463.14 EWM23323.1 - 5.6e-05 22.4 0.0 9.4e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EWM23323.1 - 0.00015 21.2 0.1 0.00067 19.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EWM23323.1 - 0.00025 21.1 0.0 0.00053 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ABC2_membrane_3 PF12698.2 EWM23323.1 - 0.00047 19.3 15.5 0.00047 19.3 10.8 1.7 1 1 1 2 2 2 1 ABC-2 family transporter protein DUF258 PF03193.11 EWM23323.1 - 0.00047 19.3 0.1 0.0008 18.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EWM23323.1 - 0.0049 17.3 0.0 0.01 16.3 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 EWM23323.1 - 0.014 15.5 0.1 0.041 14.0 0.0 1.7 2 0 0 2 2 1 0 AAA domain PDR_CDR PF06422.7 EWM23323.1 - 0.017 14.7 0.4 0.089 12.4 0.0 2.3 2 0 0 2 2 2 0 CDR ABC transporter NACHT PF05729.7 EWM23323.1 - 0.018 14.6 0.2 0.043 13.4 0.1 1.7 1 0 0 1 1 1 0 NACHT domain AAA PF00004.24 EWM23323.1 - 0.024 14.8 0.0 0.098 12.8 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 EWM23323.1 - 0.036 13.5 0.1 0.08 12.4 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 EWM23323.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_29 PF13555.1 EWM23323.1 - 0.088 12.3 0.2 0.19 11.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.12 EWM23323.1 - 0.13 11.6 0.1 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein SbcCD_C PF13558.1 EWM23323.1 - 0.14 12.0 0.1 0.97 9.3 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 EWM23323.1 - 0.21 10.6 0.0 15 4.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain DnaJ_CXXCXGXG PF00684.14 EWM23324.1 - 0.0034 17.3 11.8 0.016 15.2 8.2 2.1 1 1 0 1 1 1 1 DnaJ central domain zf-HIT PF04438.11 EWM23324.1 - 0.44 10.2 16.6 1.7 8.3 2.3 3.7 4 0 0 4 4 4 0 HIT zinc finger Herpes_UL92 PF03048.9 EWM23325.1 - 0.049 13.1 1.0 0.33 10.4 0.1 2.0 1 1 1 2 2 2 0 UL92 family DUF2378 PF09536.5 EWM23325.1 - 0.15 11.5 0.1 1.5 8.2 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2378) START PF01852.14 EWM23326.1 - 3.9e-17 62.2 0.0 7.2e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 START domain DUF3074 PF11274.3 EWM23326.1 - 0.0086 15.7 0.0 0.026 14.1 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) ApoLp-III PF07464.6 EWM23326.1 - 0.041 13.8 2.9 0.044 13.8 0.2 2.3 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Death PF00531.17 EWM23326.1 - 0.18 11.6 6.8 0.098 12.4 0.5 2.6 2 0 0 2 2 2 0 Death domain DUF1548 PF07579.6 EWM23326.1 - 0.4 10.7 1.7 2.4 8.2 0.2 2.6 1 1 2 3 3 3 0 Domain of Unknown Function (DUF1548) Prominin PF05478.6 EWM23326.1 - 0.57 7.6 1.7 9.1 3.6 0.1 2.0 2 0 0 2 2 2 0 Prominin Apolipoprotein PF01442.13 EWM23326.1 - 0.65 9.4 18.0 0.056 12.9 2.6 2.2 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF1451 PF07295.6 EWM23326.1 - 1.8 8.3 5.5 9.6 5.9 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1451) Exonuc_VII_L PF02601.10 EWM23326.1 - 3.3 6.8 6.9 17 4.4 4.7 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit TPR_MLP1_2 PF07926.7 EWM23326.1 - 8.4 6.1 11.2 33 4.2 7.8 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein CBM49 PF09478.5 EWM23327.1 - 0.00014 21.8 0.0 0.059 13.4 0.0 2.2 2 0 0 2 2 2 2 Carbohydrate binding domain CBM49 Daxx PF03344.10 EWM23327.1 - 7 5.0 29.7 5 5.4 15.6 2.0 2 0 0 2 2 2 0 Daxx Family DUF647 PF04884.9 EWM23329.1 - 1.4e-71 240.6 1.1 1.9e-71 240.1 0.8 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis ATPase_gene1 PF09527.5 EWM23329.1 - 0.075 12.8 1.7 0.16 11.8 0.5 2.0 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) OTU PF02338.14 EWM23330.1 - 4.2e-13 49.9 0.0 1.2e-12 48.5 0.0 1.8 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EWM23330.1 - 0.0035 16.7 0.0 0.085 12.1 0.1 2.2 1 1 1 2 2 2 2 Peptidase C65 Otubain Pkinase PF00069.20 EWM23331.1 - 3.2e-37 128.1 0.0 4.1e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM23331.1 - 3.9e-17 62.1 0.0 5e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EWM23331.1 - 9.8e-06 25.4 0.0 5.4e-05 23.0 0.0 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EWM23331.1 - 0.13 11.0 0.1 0.2 10.4 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RCC1 PF00415.13 EWM23332.1 - 1.9e-49 165.6 23.2 1.4e-11 44.4 0.2 8.6 7 2 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EWM23332.1 - 6.4e-33 111.6 35.6 5.7e-07 28.9 2.8 8.0 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat DUF4463 PF14703.1 EWM23332.1 - 0.03 14.8 1.2 0.065 13.7 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4463) RNase_T PF00929.19 EWM23333.1 - 1.8e-12 47.8 0.2 2.7e-12 47.2 0.2 1.3 1 0 0 1 1 1 1 Exonuclease zf-CCCH PF00642.19 EWM23333.1 - 0.051 13.2 0.6 0.096 12.3 0.4 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TFIIA PF03153.8 EWM23333.1 - 7.6 6.3 10.0 13 5.6 6.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LCAT PF02450.10 EWM23334.1 - 1.2e-40 139.7 0.0 2.8e-40 138.4 0.0 1.5 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 EWM23334.1 - 1.2e-08 35.1 1.3 2.3e-08 34.2 0.2 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM23334.1 - 4.9e-08 32.8 0.0 8.4e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EWM23334.1 - 0.00031 20.4 0.0 0.00048 19.7 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 EWM23334.1 - 0.013 15.1 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Esterase PF00756.15 EWM23334.1 - 0.013 14.8 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.15 EWM23334.1 - 0.035 13.6 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.9 EWM23334.1 - 0.065 12.5 0.1 0.13 11.5 0.0 1.4 2 0 0 2 2 2 0 Putative serine esterase (DUF676) DUF900 PF05990.7 EWM23334.1 - 0.15 11.3 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Pkinase PF00069.20 EWM23335.1 - 1.7e-73 247.0 0.0 2.7e-73 246.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM23335.1 - 1.7e-32 112.5 0.0 3.5e-32 111.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.1 EWM23335.1 - 8.6e-26 89.8 0.5 6e-12 45.5 0.4 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EWM23335.1 - 5.2e-25 84.7 0.3 7.5e-06 24.8 0.1 5.0 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EWM23335.1 - 2.6e-20 70.4 1.3 3.8e-05 23.1 0.0 5.0 4 1 1 5 5 5 3 EF-hand domain EF-hand_5 PF13202.1 EWM23335.1 - 1.3e-18 65.3 3.7 7e-06 25.1 0.0 4.1 4 0 0 4 4 3 3 EF hand EF-hand_8 PF13833.1 EWM23335.1 - 1e-13 50.6 4.2 4.6e-06 26.1 0.4 4.3 1 1 3 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EWM23335.1 - 9.6e-06 25.6 0.0 0.0025 17.8 0.0 2.6 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Kdo PF06293.9 EWM23335.1 - 0.00049 19.2 0.1 0.0014 17.7 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EWM23335.1 - 0.00056 19.7 0.2 0.0048 16.6 0.0 2.4 2 2 1 3 3 3 1 Phosphotransferase enzyme family EFhand_Ca_insen PF08726.5 EWM23335.1 - 0.00066 19.5 0.2 0.069 13.1 0.0 2.6 2 0 0 2 2 2 1 Ca2+ insensitive EF hand Choline_kinase PF01633.15 EWM23335.1 - 0.00077 19.0 0.1 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EWM23335.1 - 0.0046 16.1 0.2 0.014 14.5 0.0 1.8 2 0 0 2 2 2 1 Ecdysteroid kinase EF-hand_9 PF14658.1 EWM23335.1 - 0.01 15.7 0.7 5.2 7.0 0.0 3.5 3 1 0 3 3 2 1 EF-hand domain Toprim_2 PF13155.1 EWM23335.1 - 0.015 15.5 1.5 1.3 9.3 0.1 2.6 1 1 1 2 2 2 0 Toprim-like NAD_Gly3P_dh_C PF07479.9 EWM23335.1 - 0.025 14.2 0.2 0.87 9.3 0.0 2.7 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus HGD-D PF06050.8 EWM23335.1 - 0.047 12.5 0.1 0.24 10.2 0.0 2.1 3 0 0 3 3 3 0 2-hydroxyglutaryl-CoA dehydratase, D-component Kinase-like PF14531.1 EWM23335.1 - 0.075 11.9 0.2 0.65 8.9 0.0 2.4 2 1 1 3 3 3 0 Kinase-like PepSY_2 PF13670.1 EWM23335.1 - 0.59 10.0 4.2 12 5.8 0.3 2.7 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain TYW3 PF02676.9 EWM23337.1 - 4e-48 163.2 0.0 5.7e-48 162.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase TYW3 Met_10 PF02475.11 EWM23337.1 - 8.8e-25 87.4 0.0 1.4e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Kelch_3 PF13415.1 EWM23337.1 - 2e-11 43.6 4.6 8.6e-06 25.7 0.0 5.5 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_4 PF13418.1 EWM23337.1 - 2.2e-10 40.1 11.1 0.0029 17.3 0.1 5.4 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EWM23337.1 - 2.6e-08 33.6 0.1 0.088 12.7 0.0 5.8 6 0 0 6 6 6 1 Kelch motif Methyltransf_26 PF13659.1 EWM23337.1 - 1.5e-05 24.9 0.0 6.4e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EWM23337.1 - 4.6e-05 22.8 0.0 0.0001 21.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.5 EWM23337.1 - 0.0039 16.7 0.0 0.0073 15.8 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Kelch_2 PF07646.10 EWM23337.1 - 0.0067 16.1 6.5 26 4.7 0.1 5.1 5 0 0 5 5 5 0 Kelch motif Methyltransf_18 PF12847.2 EWM23337.1 - 0.012 16.1 0.0 0.029 14.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EWM23337.1 - 0.024 14.2 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Kelch_6 PF13964.1 EWM23337.1 - 0.082 13.1 3.9 18 5.7 0.0 4.3 4 1 1 5 5 4 0 Kelch motif Cons_hypoth95 PF03602.10 EWM23337.1 - 0.094 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltrans_SAM PF10672.4 EWM23337.1 - 0.1 11.3 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase tRNA_U5-meth_tr PF05958.6 EWM23337.1 - 0.13 10.9 0.0 0.2 10.3 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase RrnaAD PF00398.15 EWM23337.1 - 0.45 9.5 0.0 0.73 8.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF3067 PF11267.3 EWM23338.1 - 1.3e-21 76.5 0.1 1.9e-21 75.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3067) CPSase_L_D2 PF02786.12 EWM23339.1 - 7.3e-72 241.0 0.0 1.2e-71 240.3 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EWM23339.1 - 1.7e-41 140.7 0.0 3e-41 139.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EWM23339.1 - 3.2e-35 120.3 0.0 7.9e-35 119.0 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EWM23339.1 - 8.1e-18 63.8 0.6 1.8e-17 62.6 0.4 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EWM23339.1 - 4.1e-15 55.9 0.2 1.2e-14 54.4 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EWM23339.1 - 1.4e-14 53.5 0.0 1.1e-13 50.6 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EWM23339.1 - 6e-09 35.5 0.0 1.2e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 EWM23339.1 - 6.3e-08 32.1 1.2 4.5e-05 23.0 0.0 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.17 EWM23339.1 - 1.8e-06 27.4 0.0 3.4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 EWM23339.1 - 0.00076 19.7 0.7 1.8 8.9 0.2 2.9 3 0 0 3 3 3 2 HlyD family secretion protein ATP-grasp_3 PF02655.9 EWM23339.1 - 0.056 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain TPR_11 PF13414.1 EWM23341.1 - 2.6e-23 81.4 0.9 1e-08 34.6 0.5 4.3 3 1 1 4 4 4 3 TPR repeat TPR_1 PF00515.23 EWM23341.1 - 3.8e-17 61.0 0.0 0.00072 19.0 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 EWM23341.1 - 1.9e-16 58.5 1.3 0.00048 19.8 0.1 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 EWM23341.1 - 3.5e-14 53.0 2.3 1.2e-07 32.1 0.4 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EWM23341.1 - 5e-11 42.2 6.3 0.0048 17.4 0.4 6.5 4 1 3 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 EWM23341.1 - 2.6e-10 40.1 4.5 1.7e-05 24.6 1.3 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EWM23341.1 - 1.2e-06 28.2 1.9 0.011 15.5 0.8 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 EWM23341.1 - 1.5e-06 27.5 2.4 0.012 15.3 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 EWM23341.1 - 5.7e-06 26.1 0.2 0.25 11.6 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EWM23341.1 - 2e-05 24.0 0.0 0.014 15.1 0.0 4.0 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EWM23341.1 - 0.00066 19.9 0.3 0.031 14.6 0.1 3.1 2 1 3 5 5 4 2 Tetratricopeptide repeat FAT PF02259.18 EWM23341.1 - 0.005 15.8 0.0 0.008 15.1 0.0 1.3 1 0 0 1 1 1 1 FAT domain TPR_6 PF13174.1 EWM23341.1 - 0.68 10.5 4.9 2.6 8.6 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EWM23342.1 - 6.4e-22 76.9 1.0 7.4e-09 35.1 0.5 3.3 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 EWM23342.1 - 1.9e-15 55.7 0.4 0.00053 19.4 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 EWM23342.1 - 1.3e-14 52.8 1.0 0.00035 20.2 0.1 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 EWM23342.1 - 3.9e-10 39.5 9.7 1.4e-05 24.9 1.5 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EWM23342.1 - 1.3e-09 38.4 1.7 8.7e-08 32.6 0.4 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EWM23342.1 - 4.1e-07 29.2 1.5 0.0086 15.8 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 EWM23342.1 - 1.1e-06 28.4 1.5 0.0093 15.8 0.9 3.1 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 EWM23342.1 - 1.3e-06 28.4 5.7 0.0028 18.1 0.2 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 EWM23342.1 - 4.7e-06 26.3 0.1 0.18 12.0 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EWM23342.1 - 0.00011 21.6 0.5 0.01 15.5 0.0 3.3 3 1 1 4 4 4 1 Tetratricopeptide repeat FAT PF02259.18 EWM23342.1 - 0.0034 16.4 0.0 0.0051 15.8 0.0 1.3 1 0 0 1 1 1 1 FAT domain TPR_19 PF14559.1 EWM23342.1 - 0.0039 17.4 0.7 0.022 15.0 0.1 2.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EWM23342.1 - 0.53 10.2 2.9 1.3 9.0 1.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EWM23342.1 - 0.89 10.1 4.6 1.9 9.0 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Syja_N PF02383.13 EWM23344.1 - 3.5e-52 177.1 0.0 6.5e-44 149.9 0.0 2.4 2 1 0 2 2 2 2 SacI homology domain SPT6_acidic PF14632.1 EWM23345.1 - 8.2 6.6 12.8 0.9 9.7 3.3 2.2 1 1 1 2 2 2 0 Acidic N-terminal SPT6 Myosin_tail_1 PF01576.14 EWM23347.1 - 0.0011 16.7 8.4 0.0011 16.7 5.8 2.5 1 1 0 2 2 2 1 Myosin tail KSR1-SAM PF13543.1 EWM23347.1 - 0.07 12.9 0.3 0.07 12.9 0.2 2.1 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 DUF837 PF05769.6 EWM23347.1 - 1.2 8.6 20.7 0.22 11.0 8.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF837) NPV_P10 PF05531.7 EWM23347.1 - 3.9 7.8 12.6 4.4 7.6 2.4 3.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein IF-2B PF01008.12 EWM23347.1 - 8.3 5.3 16.0 0.077 11.9 5.1 1.8 2 0 0 2 2 2 0 Initiation factor 2 subunit family 2OG-FeII_Oxy_2 PF13532.1 EWM23348.1 - 1.6e-08 34.6 0.1 2.3e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UPF0114 PF03350.11 EWM23349.1 - 0.0074 16.1 0.1 0.033 14.1 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized protein family, UPF0114 DUF4023 PF13215.1 EWM23349.1 - 0.076 12.7 0.4 0.076 12.7 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4023) DUF3785 PF12653.2 EWM23349.1 - 0.16 11.8 2.8 0.23 11.2 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3785) SAP18 PF06487.7 EWM23350.1 - 1.5e-32 111.9 0.0 1.7e-32 111.7 0.0 1.0 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Asn_synthase PF00733.16 EWM23351.1 - 5.6e-71 239.0 0.0 7.5e-71 238.6 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EWM23351.1 - 1.5e-38 131.3 0.0 2.7e-38 130.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EWM23351.1 - 1.7e-30 105.7 0.0 3.5e-30 104.6 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EWM23351.1 - 2.4e-08 33.4 0.1 4.1e-08 32.6 0.1 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 EWM23351.1 - 0.0007 18.4 0.0 2.5 6.6 0.0 3.0 1 1 1 3 3 3 2 Glutamine amidotransferases class-II NAD_synthase PF02540.12 EWM23351.1 - 0.13 11.0 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 NAD synthase Dynamin_M PF01031.15 EWM23355.1 - 8.5e-97 323.4 0.0 1.3e-96 322.8 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EWM23355.1 - 5.5e-55 185.7 0.0 8e-55 185.1 0.0 1.3 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EWM23355.1 - 0.0033 17.3 0.0 0.015 15.2 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EWM23355.1 - 0.024 15.1 0.0 0.045 14.2 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein GTP_EFTU PF00009.22 EWM23355.1 - 0.063 12.7 0.1 40 3.5 0.0 3.1 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AIG1 PF04548.11 EWM23355.1 - 0.13 11.3 0.1 13 4.8 0.0 2.3 2 0 0 2 2 2 0 AIG1 family Paf1 PF03985.8 EWM23356.1 - 0.00011 21.0 0.0 0.00026 19.8 0.0 1.7 1 1 0 1 1 1 1 Paf1 Paf1 PF03985.8 EWM23357.1 - 0.00011 21.1 0.0 0.00026 19.8 0.0 1.7 1 1 0 1 1 1 1 Paf1 RNA_pol_Rpb6 PF01192.17 EWM23358.1 - 3.7e-18 65.0 0.7 7e-18 64.1 0.5 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb6 Erv26 PF04148.8 EWM23359.1 - 1e-43 149.1 13.6 1.9e-43 148.2 9.4 1.4 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 DUF1418 PF07214.7 EWM23359.1 - 0.0074 15.8 0.3 0.013 15.0 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1418) UPF0182 PF03699.8 EWM23359.1 - 2.6 5.8 4.7 0.32 8.8 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0182) Hist_deacetyl PF00850.14 EWM23360.1 - 7.7e-39 133.8 0.0 1.9e-38 132.5 0.0 1.5 1 1 0 1 1 1 1 Histone deacetylase domain GED PF02212.13 EWM23361.1 - 5.9e-30 103.0 3.2 6.7e-30 102.8 2.2 1.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain TPR_12 PF13424.1 EWM23361.1 - 0.078 12.9 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3506 PF12014.3 EWM23362.1 - 1.1e-09 38.1 0.0 2.6e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) RNA_pol_A_bac PF01000.21 EWM23363.1 - 5.6e-21 74.8 0.0 1.7e-20 73.2 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EWM23363.1 - 7.4e-17 60.2 0.0 9.9e-17 59.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_7 PF12838.2 EWM23363.1 - 0.0054 17.0 0.1 0.012 15.9 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain DUF2284 PF10050.4 EWM23363.1 - 0.04 13.5 0.3 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 Predicted metal-binding protein (DUF2284) Fer4_10 PF13237.1 EWM23363.1 - 0.067 13.0 0.4 0.15 11.8 0.3 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain RNA_pol_L_2 PF13656.1 EWM23363.1 - 0.12 11.8 0.0 11 5.5 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain SEC-C PF02810.10 EWM23364.1 - 0.00017 21.0 6.0 0.00026 20.4 4.1 1.3 1 0 0 1 1 1 1 SEC-C motif Dynamin_N PF00350.18 EWM23365.1 - 3.1e-14 53.1 0.0 1.8e-13 50.6 0.0 2.3 2 1 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 EWM23365.1 - 7.5e-12 44.6 0.1 6.5e-05 21.8 0.0 3.0 3 0 0 3 3 3 2 Dynamin central region MMR_HSR1 PF01926.18 EWM23365.1 - 0.0029 17.5 0.0 0.14 12.0 0.0 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase GED PF02212.13 EWM23365.1 - 0.0049 16.7 0.5 0.0049 16.7 0.3 2.6 3 0 0 3 3 2 1 Dynamin GTPase effector domain DUF258 PF03193.11 EWM23365.1 - 0.0057 15.8 0.0 1.5 8.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 EWM23365.1 - 0.011 15.2 0.0 0.026 14.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Med9 PF07544.8 EWM23365.1 - 0.026 14.2 0.3 0.97 9.2 0.1 2.8 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 AAA_17 PF13207.1 EWM23365.1 - 0.062 14.1 0.5 1.2 10.0 0.0 3.0 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EWM23365.1 - 0.08 13.2 0.0 0.31 11.3 0.0 2.0 1 0 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 EWM23365.1 - 0.1 12.0 0.1 9.9 5.6 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 EWM23365.1 - 0.49 10.6 3.3 0.51 10.6 0.4 2.3 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EWM23366.1 - 4.1e-19 69.0 0.0 8.8e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EWM23366.1 - 1.2e-14 53.7 0.1 2.2e-08 33.2 0.0 2.2 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 EWM23366.1 - 0.00027 20.8 0.0 0.00099 19.0 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.13 EWM23366.1 - 0.00032 20.5 2.5 0.001 18.9 1.8 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain PduV-EutP PF10662.4 EWM23366.1 - 0.0019 17.6 0.1 0.67 9.4 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EWM23366.1 - 0.0023 18.4 0.1 0.015 15.7 0.0 2.2 1 1 0 2 2 2 1 Miro-like protein ABC_tran PF00005.22 EWM23366.1 - 0.032 14.5 0.0 0.16 12.2 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_21 PF13304.1 EWM23366.1 - 0.033 14.1 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Aminotran_1_2 PF00155.16 EWM23367.1 - 3.7e-46 157.7 0.0 4.4e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EWM23367.1 - 0.004 15.4 0.0 0.0068 14.7 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF694 PF05107.7 EWM23367.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF694) WD40 PF00400.27 EWM23368.1 - 3.9e-53 175.5 4.9 1.3e-08 34.4 0.0 8.5 8 1 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 EWM23368.1 - 0.0042 16.8 0.0 1.1 8.9 0.0 2.8 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.1 EWM23368.1 - 0.25 11.6 7.7 17 5.8 0.1 5.4 6 0 0 6 6 6 0 PQQ-like domain Nup160 PF11715.3 EWM23368.1 - 0.34 9.0 1.3 4.9 5.1 0.0 3.0 3 1 1 4 4 4 0 Nucleoporin Nup120/160 LMWPc PF01451.16 EWM23369.1 - 1e-27 97.1 0.0 1.2e-26 93.7 0.0 2.0 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase NT-C2 PF10358.4 EWM23370.1 - 3.8e-11 42.6 0.2 8.9e-11 41.4 0.1 1.6 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DUF2373 PF10180.4 EWM23371.1 - 1.2e-13 50.4 0.1 2.1e-13 49.5 0.1 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) TPR_MLP1_2 PF07926.7 EWM23372.1 - 1.7e-06 27.8 50.3 2.1e-05 24.2 16.4 2.5 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein Seryl_tRNA_N PF02403.17 EWM23372.1 - 9.7e-05 22.3 13.5 9.7e-05 22.3 9.3 3.8 1 1 3 4 4 4 1 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 EWM23372.1 - 0.00018 21.1 47.3 0.0037 16.8 8.8 3.1 1 1 1 2 2 2 1 IncA protein Tropomyosin PF00261.15 EWM23372.1 - 0.0018 17.4 51.5 0.17 10.9 9.9 3.4 1 1 2 3 3 3 2 Tropomyosin Cast PF10174.4 EWM23372.1 - 0.0021 16.2 48.1 0.0036 15.4 33.2 1.4 1 1 1 2 2 2 1 RIM-binding protein of the cytomatrix active zone AAA_27 PF13514.1 EWM23372.1 - 0.025 12.2 34.5 0.034 11.8 23.9 1.1 1 0 0 1 1 1 0 AAA domain WEMBL PF05701.6 EWM23372.1 - 0.026 13.0 50.8 0.13 10.7 35.2 1.9 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Filament PF00038.16 EWM23372.1 - 0.032 13.6 42.3 0.084 12.3 9.4 3.0 1 1 2 3 3 3 0 Intermediate filament protein MscS_porin PF12795.2 EWM23372.1 - 0.057 12.7 43.5 0.019 14.3 5.7 2.2 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Tropomyosin_1 PF12718.2 EWM23372.1 - 0.067 13.0 56.3 0.53 10.1 13.5 3.8 1 1 2 3 3 3 0 Tropomyosin like DUF948 PF06103.6 EWM23372.1 - 0.084 12.7 0.3 0.084 12.7 0.2 3.7 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) GAS PF13851.1 EWM23372.1 - 0.14 11.3 45.7 0.18 11.0 20.3 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 EWM23372.1 - 0.17 11.0 16.1 0.041 13.0 1.9 2.8 1 1 2 3 3 3 0 Reovirus sigma C capsid protein CCDC92 PF14916.1 EWM23372.1 - 0.23 11.0 7.7 1.3 8.6 0.6 3.5 2 1 1 3 3 3 0 Coiled-coil domain of unknown function KNOX2 PF03791.8 EWM23372.1 - 0.36 10.1 3.1 2.7 7.3 0.4 3.2 2 1 0 2 2 2 0 KNOX2 domain CobN-Mg_chel PF02514.11 EWM23372.1 - 0.69 7.2 18.3 0.87 6.8 12.7 1.1 1 0 0 1 1 1 0 CobN/Magnesium Chelatase MAD PF05557.8 EWM23372.1 - 0.87 7.5 42.6 1.3 7.0 29.5 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein AAA_13 PF13166.1 EWM23372.1 - 1.1 7.6 41.4 0.23 9.8 15.3 2.3 1 1 1 2 2 2 0 AAA domain ERM PF00769.14 EWM23372.1 - 1.3 8.5 47.6 1.9 7.9 33.0 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Herpes_U30 PF04523.8 EWM23372.1 - 1.3 6.3 18.0 8.4 3.7 12.2 1.9 1 1 0 1 1 1 0 Herpes virus tegument protein U30 ADIP PF11559.3 EWM23372.1 - 1.7 8.5 44.2 1.7 8.5 6.4 3.7 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.14 EWM23372.1 - 2.2 6.0 31.3 13 3.4 21.2 1.8 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-F_leu_zip PF10473.4 EWM23372.1 - 2.6 7.8 52.6 36 4.2 21.1 3.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.7 EWM23372.1 - 4 7.7 17.5 16 5.8 4.8 4.7 1 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.5 EWM23372.1 - 5.4 7.1 27.4 3.9 7.5 4.6 3.4 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Allexi_40kDa PF05549.6 EWM23372.1 - 7.2 5.8 21.9 0.16 11.2 4.5 2.3 1 1 1 2 2 2 0 Allexivirus 40kDa protein Prefoldin_2 PF01920.15 EWM23372.1 - 7.7 6.3 46.0 1.4 8.6 1.8 5.1 1 1 3 4 4 4 0 Prefoldin subunit PhoU PF01895.14 EWM23372.1 - 7.8 7.0 21.5 7.9 7.0 1.4 3.7 2 2 1 3 3 3 0 PhoU domain SSB PF00436.20 EWM23373.1 - 4.6e-24 84.2 0.1 7e-24 83.6 0.0 1.3 1 0 0 1 1 1 1 Single-strand binding protein family ADH_N PF08240.7 EWM23374.1 - 2.7e-31 107.5 0.2 4.7e-31 106.7 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EWM23374.1 - 6.2e-15 54.9 0.2 1e-14 54.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RskA PF10099.4 EWM23375.1 - 0.015 15.0 0.4 2.1 8.0 0.0 2.4 2 0 0 2 2 2 0 Anti-sigma-K factor rskA APC_CDC26 PF10471.4 EWM23376.1 - 7.2e-14 52.2 0.1 8e-14 52.1 0.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 Proteasome PF00227.21 EWM23378.1 - 5.1e-47 159.6 1.0 5.8e-47 159.4 0.7 1.0 1 0 0 1 1 1 1 Proteasome subunit DEAD PF00270.24 EWM23379.1 - 1.2e-31 109.4 0.0 5.6e-19 68.2 0.0 2.9 2 1 1 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EWM23379.1 - 9.5e-21 73.4 0.0 2.6e-20 72.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain BRX PF08381.6 EWM23379.1 - 0.028 13.4 0.2 0.069 12.2 0.1 1.6 1 0 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 CMS1 PF14617.1 EWM23379.1 - 0.12 11.4 0.0 0.12 11.4 0.0 3.1 2 1 1 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit Cpn10 PF00166.16 EWM23380.1 - 1.5e-07 31.2 0.0 1.9e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Ank_2 PF12796.2 EWM23384.1 - 5.4e-16 58.7 1.1 8.6e-16 58.0 0.8 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EWM23384.1 - 1.2e-11 43.7 4.1 7.6e-05 22.3 0.0 3.3 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EWM23384.1 - 1.5e-11 43.3 0.1 0.00038 20.4 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EWM23384.1 - 4.4e-11 42.9 0.9 1.8e-05 25.1 0.2 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EWM23384.1 - 6.3e-09 35.7 2.3 3.3e-05 23.9 0.0 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) WW PF00397.21 EWM23384.1 - 7.2e-07 28.9 0.1 1.6e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 WW domain VRR_NUC PF08774.6 EWM23386.1 - 1e-05 25.4 0.1 1.9e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 VRR-NUC domain Vps26 PF03643.10 EWM23387.1 - 3.9e-110 366.9 0.6 4.9e-110 366.6 0.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EWM23387.1 - 0.01 15.6 0.8 0.24 11.2 0.1 3.2 3 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain DUF2946 PF11162.3 EWM23388.1 - 0.052 13.7 0.4 0.098 12.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) Semialdhyde_dhC PF02774.13 EWM23389.1 - 2.7e-45 154.4 0.0 3.6e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EWM23389.1 - 2.3e-28 98.9 0.0 3.7e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EWM23389.1 - 0.0074 16.6 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DXP_reductoisom PF02670.11 EWM23389.1 - 0.11 13.0 0.0 2.2 8.7 0.0 2.4 1 1 1 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase NmrA PF05368.8 EWM23389.1 - 0.13 11.5 0.1 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Peptidase_C69 PF03577.10 EWM23390.1 - 1.4e-45 155.8 0.5 9.2e-38 130.1 0.0 2.5 2 1 0 2 2 2 2 Peptidase family C69 RMP PF14996.1 EWM23390.1 - 0.02 14.8 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 Retinal Maintenance PUF PF00806.14 EWM23392.1 - 3e-52 171.2 1.4 3.6e-07 29.2 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Mito_carr PF00153.22 EWM23393.1 - 1.9e-32 110.7 0.5 1.7e-10 40.4 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein LSM PF01423.17 EWM23394.1 - 9.1e-10 37.9 0.0 1e-06 28.1 0.0 2.3 2 0 0 2 2 2 2 LSM domain NifU PF01106.12 EWM23395.1 - 1.9e-21 75.6 0.4 7.7e-21 73.6 0.1 2.1 2 0 0 2 2 2 1 NifU-like domain DUF4456 PF14644.1 EWM23395.1 - 0.014 14.6 0.2 0.023 13.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) MAPEG PF01124.13 EWM23396.1 - 9.5e-16 57.5 1.1 1.3e-15 57.1 0.8 1.1 1 0 0 1 1 1 1 MAPEG family RDD PF06271.7 EWM23396.1 - 3.5 7.5 9.5 0.1 12.5 1.1 2.2 2 1 0 2 2 2 0 RDD family CbtB PF09489.5 EWM23396.1 - 5.1 7.0 5.1 1.1 9.2 0.3 2.2 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) DUF1469 PF07332.6 EWM23396.1 - 9.3 6.0 12.4 19 4.9 8.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) DAO PF01266.19 EWM23398.1 - 4.2e-49 167.3 0.2 5.8e-49 166.9 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EWM23398.1 - 1e-06 27.9 2.3 0.019 13.8 0.6 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 EWM23398.1 - 0.00032 19.9 1.8 0.0018 17.4 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EWM23398.1 - 0.00094 18.3 0.5 1.1 8.2 0.0 2.6 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.9 EWM23398.1 - 0.0014 18.5 1.0 0.018 14.9 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EWM23398.1 - 0.17 10.7 0.5 0.34 9.7 0.3 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EWM23398.1 - 0.71 9.9 3.3 2.7 8.1 0.2 3.2 4 0 0 4 4 4 0 NAD(P)-binding Rossmann-like domain TCTP PF00838.12 EWM23400.1 - 1.3e-32 113.0 0.3 1.5e-32 112.8 0.2 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Dynein_heavy PF03028.10 EWM23402.1 - 9.9e-48 162.7 0.0 1.1e-47 162.5 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor Peptidase_M48 PF01435.13 EWM23403.1 - 1.2e-18 67.4 0.0 6.7e-18 65.0 0.0 2.0 1 1 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 EWM23403.1 - 0.0073 15.3 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 BlaR1 peptidase M56 DUF2201_N PF13203.1 EWM23403.1 - 0.015 14.4 0.2 0.35 10.0 0.0 2.2 2 0 0 2 2 2 0 Putative metallopeptidase domain DUF955 PF06114.8 EWM23403.1 - 0.14 11.8 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF955) Exo70 PF03081.10 EWM23404.1 - 5.3e-34 117.6 0.1 1.6e-33 116.0 0.0 1.9 2 1 0 2 2 2 1 Exo70 exocyst complex subunit AAA_6 PF12774.2 EWM23405.1 - 2.3e-62 210.5 0.2 2.6e-62 210.3 0.2 1.0 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA PF00004.24 EWM23405.1 - 0.012 15.8 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EWM23405.1 - 0.082 13.7 0.0 0.11 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EWM23405.1 - 0.085 12.5 0.0 0.46 10.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EWM23405.1 - 0.12 12.5 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EWM23405.1 - 0.14 11.8 0.4 0.31 10.8 0.3 1.5 1 0 0 1 1 1 0 Part of AAA domain Topoisom_bac PF01131.15 EWM23406.1 - 5.5e-18 64.9 0.0 8e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EWM23406.1 - 2.1e-17 62.9 0.0 3.8e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.1 EWM23406.1 - 0.043 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Toprim domain Mucin PF01456.12 EWM23406.1 - 7.5 6.3 13.4 6.9 6.4 6.7 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein RRM_1 PF00076.17 EWM23407.1 - 7.4e-21 73.5 0.0 1.1e-10 40.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM23407.1 - 2.7e-19 68.7 0.0 4.5e-11 42.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM23407.1 - 1.4e-12 47.4 0.0 7.4e-06 25.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.1 EWM23407.1 - 0.045 13.2 0.0 1.9 8.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) TBCC PF07986.7 EWM23408.1 - 4.2e-21 74.5 0.0 6.2e-21 74.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.6 EWM23408.1 - 0.082 12.2 0.1 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal YjgF_endoribonc PF14588.1 EWM23409.1 - 2.8e-31 108.4 0.1 3.1e-31 108.3 0.0 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.16 EWM23409.1 - 1.7e-18 66.5 0.0 3e-18 65.7 0.0 1.4 1 1 1 2 2 2 1 Endoribonuclease L-PSP DUF2233 PF09992.4 EWM23409.1 - 0.035 14.1 0.0 0.043 13.8 0.0 1.1 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2233) MazG PF03819.12 EWM23409.1 - 0.087 12.7 0.1 0.31 11.0 0.1 1.8 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain Topoisom_bac PF01131.15 EWM23410.1 - 7e-40 137.0 0.0 8.3e-40 136.8 0.0 1.0 1 0 0 1 1 1 1 DNA topoisomerase KH_1 PF00013.24 EWM23411.1 - 1.5e-26 91.8 3.2 2e-10 40.1 0.1 3.6 4 0 0 4 4 4 3 KH domain KH_3 PF13014.1 EWM23411.1 - 2.4e-21 74.9 4.5 2.7e-08 33.2 0.0 3.8 4 0 0 4 4 4 3 KH domain KH_2 PF07650.12 EWM23411.1 - 0.15 11.5 2.9 5.5 6.6 0.1 2.6 3 0 0 3 3 3 0 KH domain Peptidase_A22B PF04258.8 EWM23412.1 - 1e-67 228.7 8.1 1.5e-67 228.1 5.6 1.2 1 0 0 1 1 1 1 Signal peptide peptidase PA PF02225.17 EWM23412.1 - 1.7e-06 27.6 0.0 0.00016 21.2 0.0 2.6 2 0 0 2 2 2 1 PA domain Tox-HNH-HHH PF15637.1 EWM23412.1 - 0.13 11.9 0.0 1.1 9.0 0.0 2.0 2 0 0 2 2 2 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif RAP PF08373.5 EWM23413.1 - 0.0026 17.5 0.0 0.0051 16.5 0.0 1.5 1 0 0 1 1 1 1 RAP domain ADP_ribosyl_GH PF03747.9 EWM23414.1 - 1.4e-24 87.3 0.6 1.8e-24 87.0 0.4 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase DUF4231 PF14015.1 EWM23414.1 - 6.2 6.8 6.3 46 4.0 4.4 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) Suf PF05843.9 EWM23415.1 - 8.4e-28 97.8 0.0 1.2e-23 84.2 0.0 3.8 4 0 0 4 4 4 3 Suppressor of forked protein (Suf) ACOX PF01756.14 EWM23417.1 - 3.3e-28 98.3 0.0 7.1e-28 97.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EWM23417.1 - 2.1e-26 92.6 0.0 3.7e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EWM23417.1 - 4e-08 32.6 0.2 9.3e-08 31.4 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Toxin_5 PF05294.8 EWM23417.1 - 0.058 13.6 3.6 0.13 12.5 2.5 1.5 1 0 0 1 1 1 0 Scorpion short toxin PGM_PMM_I PF02878.11 EWM23419.1 - 0.017 14.5 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I DUF3208 PF11482.3 EWM23419.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3208) ESSS PF10183.4 EWM23420.1 - 1.1 9.6 4.0 0.59 10.5 0.8 2.1 2 1 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) HMG_box_2 PF09011.5 EWM23421.1 - 5.2e-12 45.9 7.4 2.4e-07 31.0 0.5 2.7 2 1 0 2 2 2 2 HMG-box domain HMG_box PF00505.14 EWM23421.1 - 3e-11 43.4 2.8 6.6e-05 23.1 0.1 2.6 2 0 0 2 2 2 2 HMG (high mobility group) box UPF0278 PF08745.6 EWM23421.1 - 0.22 10.7 1.3 1.5 8.0 0.3 2.0 2 0 0 2 2 2 0 UPF0278 family DUF3007 PF11460.3 EWM23421.1 - 1.2 9.2 3.3 6.2 6.9 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) Mso1_Sec1_bdg PF14475.1 EWM23423.1 - 0.046 13.1 0.3 0.089 12.2 0.2 1.4 1 0 0 1 1 1 0 Sec1-binding region of Mso1 Retinal PF15449.1 EWM23423.1 - 1.2 6.7 7.2 1.3 6.6 5.0 1.0 1 0 0 1 1 1 0 Retinal protein Mec-17 PF05301.6 EWM23424.1 - 1.2e-24 86.4 0.0 2.1e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Touch receptor neuron protein Mec-17 RUN PF02759.14 EWM23426.1 - 0.033 13.9 0.0 0.038 13.7 0.0 1.1 1 0 0 1 1 1 0 RUN domain PH_8 PF15409.1 EWM23426.1 - 0.073 13.1 0.0 0.091 12.8 0.0 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain Alpha_adaptinC2 PF02883.15 EWM23428.1 - 0.0067 16.7 0.0 0.02 15.1 0.0 1.7 1 1 0 1 1 1 1 Adaptin C-terminal domain Alpha_adaptin_C PF02296.11 EWM23428.1 - 0.079 12.9 0.0 0.26 11.2 0.0 1.9 1 1 0 1 1 1 0 Alpha adaptin AP2, C-terminal domain HECT PF00632.20 EWM23431.1 - 3.2e-59 200.6 0.0 5e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.23 EWM23431.1 - 1.4e-16 60.7 0.3 2.6e-16 59.8 0.2 1.5 1 0 0 1 1 1 1 SPRY domain DUF946 PF06101.6 EWM23431.1 - 2.3e-07 29.2 0.0 0.00011 20.3 0.0 2.1 1 1 1 2 2 2 2 Plant protein of unknown function (DUF946) Glyoxalase_2 PF12681.2 EWM23432.1 - 1.2e-12 48.4 0.0 1.9e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EWM23432.1 - 1.3e-06 28.4 0.0 2.7e-06 27.3 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EWM23432.1 - 0.0013 18.7 0.0 0.0025 17.8 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Kelch_4 PF13418.1 EWM23434.1 - 1.2e-20 73.0 12.4 2.1e-08 33.7 0.3 4.0 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.1 EWM23434.1 - 8e-18 64.0 8.5 2.9e-07 30.4 0.2 4.7 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.20 EWM23434.1 - 6.8e-13 47.9 17.4 5.7e-10 38.5 0.9 4.4 4 1 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 EWM23434.1 - 5.7e-12 44.8 12.9 8.5e-08 31.6 0.4 3.9 3 1 0 3 3 3 3 Kelch motif Kelch_5 PF13854.1 EWM23434.1 - 4.7e-10 39.1 14.6 4.2e-07 29.7 0.7 3.8 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.1 EWM23434.1 - 7.5e-10 38.5 10.0 2e-06 27.6 0.3 3.8 2 1 1 3 3 3 2 Kelch motif CK1gamma_C PF12605.3 EWM23438.1 - 0.011 16.2 0.9 0.012 16.1 0.6 1.1 1 0 0 1 1 1 0 Casein kinase 1 gamma C terminal YjgF_endoribonc PF14588.1 EWM23442.1 - 1.7e-28 99.4 0.0 2.1e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.16 EWM23442.1 - 2.4e-16 59.6 0.0 3.9e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Endoribonuclease L-PSP 2-oxoacid_dh PF00198.18 EWM23444.1 - 1.9e-62 210.5 0.0 3.6e-62 209.6 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EWM23444.1 - 7.5e-59 195.3 18.0 1.7e-20 72.4 0.6 3.6 3 0 0 3 3 3 3 Biotin-requiring enzyme E3_binding PF02817.12 EWM23444.1 - 4.1e-22 77.5 5.1 9.8e-13 47.5 0.2 2.8 2 0 0 2 2 2 2 e3 binding domain Biotin_lipoyl_2 PF13533.1 EWM23444.1 - 2.9e-17 62.0 7.0 7.7e-05 22.2 0.0 4.6 4 1 1 5 5 5 3 Biotin-lipoyl like HlyD_2 PF12700.2 EWM23444.1 - 5.5e-09 35.6 3.1 0.032 13.4 0.0 3.8 3 1 1 4 4 4 3 HlyD family secretion protein PYNP_C PF07831.8 EWM23444.1 - 4.4e-07 29.2 2.1 1.4 8.4 0.0 4.6 4 0 0 4 4 4 3 Pyrimidine nucleoside phosphorylase C-terminal domain PASTA PF03793.14 EWM23444.1 - 8.2e-06 25.3 2.5 1.2 8.8 0.1 3.7 3 0 0 3 3 3 2 PASTA domain DUF2118 PF09891.4 EWM23444.1 - 9e-06 25.4 2.0 0.64 9.7 0.1 4.2 3 1 1 4 4 4 2 Uncharacterized protein conserved in archaea (DUF2118) HlyD_3 PF13437.1 EWM23444.1 - 2.3e-05 24.6 6.6 3.5 8.0 0.1 4.9 3 2 2 5 5 5 2 HlyD family secretion protein RnfC_N PF13375.1 EWM23444.1 - 0.00024 20.7 7.2 0.045 13.4 0.1 4.1 2 1 2 4 4 4 1 RnfC Barrel sandwich hybrid domain GCV_H PF01597.14 EWM23444.1 - 0.00082 19.0 8.5 1.1 8.9 0.2 3.4 3 0 0 3 3 3 3 Glycine cleavage H-protein QRPTase_N PF02749.11 EWM23444.1 - 0.0015 18.3 1.4 33 4.3 0.0 4.6 4 0 0 4 4 4 0 Quinolinate phosphoribosyl transferase, N-terminal domain PTS_EIIA_1 PF00358.15 EWM23444.1 - 0.0044 16.5 0.7 5.7 6.5 0.0 3.5 3 0 0 3 3 3 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 PS_Dcarbxylase PF02666.10 EWM23444.1 - 0.013 14.8 0.3 10 5.3 0.0 3.6 4 0 0 4 4 4 0 Phosphatidylserine decarboxylase NfeD PF01957.13 EWM23444.1 - 0.017 15.2 11.6 1.7 8.7 0.2 4.2 4 0 0 4 4 4 0 NfeD-like C-terminal, partner-binding NQRA PF05896.6 EWM23444.1 - 0.024 13.8 6.6 1.2 8.2 0.2 3.2 2 1 0 3 3 3 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) Imm5 PF14423.1 EWM23444.1 - 0.026 14.1 1.4 3.7 7.1 0.0 3.1 3 0 0 3 3 3 0 Immunity protein Imm5 Peptidase_M23 PF01551.17 EWM23444.1 - 0.19 11.8 6.1 9.2 6.3 0.0 4.0 4 0 0 4 4 4 0 Peptidase family M23 NAD_binding_8 PF13450.1 EWM23446.1 - 0.082 12.9 0.1 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF3995 PF13160.1 EWM23446.1 - 0.086 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3995) DUF4449 PF14613.1 EWM23446.1 - 0.19 11.6 1.2 0.28 11.1 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) NAD_binding_8 PF13450.1 EWM23447.1 - 0.079 12.9 0.1 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF3995 PF13160.1 EWM23447.1 - 0.087 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3995) Myb_DNA-binding PF00249.26 EWM23448.1 - 3.7e-25 87.7 6.9 2.1e-14 53.3 0.8 4.1 6 0 0 6 6 6 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EWM23448.1 - 1.1e-22 79.9 2.2 1.2e-17 63.7 0.2 3.3 2 1 1 3 3 2 2 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EWM23448.1 - 0.052 13.4 1.6 14 5.6 0.0 3.8 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EWM23448.1 - 0.063 13.4 9.7 1.6 8.8 1.8 3.4 3 1 1 4 4 3 0 Myb/SANT-like DNA-binding domain RRN3 PF05327.6 EWM23448.1 - 0.074 11.1 2.2 0.089 10.8 1.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Daxx PF03344.10 EWM23448.1 - 0.15 10.5 13.2 0.19 10.2 9.2 1.0 1 0 0 1 1 1 0 Daxx Family TFIIF_alpha PF05793.7 EWM23448.1 - 0.16 10.2 13.1 0.2 9.9 9.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pox_Ag35 PF03286.9 EWM23448.1 - 0.36 10.3 5.0 0.52 9.8 3.5 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nucleoplasmin PF03066.10 EWM23448.1 - 0.81 9.1 8.6 1.4 8.4 6.0 1.4 1 0 0 1 1 1 0 Nucleoplasmin IFT57 PF10498.4 EWM23448.1 - 1.9 7.1 7.5 2.8 6.6 5.2 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Myc_N PF01056.13 EWM23448.1 - 3.6 6.6 6.5 4.8 6.2 4.5 1.2 1 0 0 1 1 1 0 Myc amino-terminal region TRAP_alpha PF03896.11 EWM23448.1 - 3.9 6.3 5.7 6.1 5.7 3.9 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC27 PF09507.5 EWM23448.1 - 4.3 6.4 13.4 5.9 6.0 9.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDC45 PF02724.9 EWM23448.1 - 5.3 4.9 10.0 7 4.5 7.0 1.1 1 0 0 1 1 1 0 CDC45-like protein ILVD_EDD PF00920.16 EWM23449.1 - 1.2e-66 225.2 0.0 1.4e-66 225.0 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family Aldedh PF00171.17 EWM23451.1 - 2.9e-24 85.2 0.0 3.5e-24 84.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF202 PF02656.10 EWM23453.1 - 6.1e-14 52.0 4.2 9e-14 51.4 2.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Clc-like PF07062.7 EWM23453.1 - 0.019 14.2 0.2 0.026 13.7 0.1 1.1 1 0 0 1 1 1 0 Clc-like Hydrolase PF00702.21 EWM23454.1 - 5.4e-19 69.4 0.5 7.8e-19 68.9 0.3 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EWM23454.1 - 1.2e-08 35.3 0.0 1.8e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EWM23454.1 - 0.00013 21.6 0.0 0.00022 20.9 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EWM23455.1 - 1.9e-31 110.1 0.2 2.7e-31 109.6 0.2 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EWM23455.1 - 5e-13 49.6 0.0 7.5e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EWM23455.1 - 2.9e-05 23.7 0.1 0.00041 20.0 0.0 2.0 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EWM23455.1 - 0.0076 16.1 0.0 0.043 13.6 0.0 2.2 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EWM23455.1 - 0.017 15.3 0.0 0.041 14.0 0.0 1.7 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase FG-GAP PF01839.18 EWM23456.1 - 4.5e-29 99.3 30.4 1.1e-05 24.9 0.1 6.0 5 0 0 5 5 5 5 FG-GAP repeat VCBS PF13517.1 EWM23456.1 - 1.8e-17 63.4 22.0 1.3e-07 31.8 0.7 5.7 4 1 1 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.3 EWM23456.1 - 0.024 14.0 14.6 3.7 6.9 0.1 5.4 4 2 2 6 6 6 0 Insecticide toxin TcdB middle/N-terminal region FG-GAP_2 PF14312.1 EWM23456.1 - 0.047 13.7 18.1 0.38 10.7 0.4 6.2 6 1 0 6 6 6 0 FG-GAP repeat E1-E2_ATPase PF00122.15 EWM23457.1 - 7.6e-10 38.2 0.0 7.9e-10 38.1 0.0 1.0 1 0 0 1 1 1 1 E1-E2 ATPase DUF3752 PF12572.3 EWM23459.1 - 1.8e-06 28.1 9.2 2e-06 27.9 6.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) FAM178 PF14816.1 EWM23459.1 - 0.049 12.3 0.4 0.056 12.1 0.3 1.1 1 0 0 1 1 1 0 Family of unknown function, FAM178 Complex1_30kDa PF00329.14 EWM23460.1 - 0.0027 17.9 0.0 0.0034 17.6 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit DUF4148 PF13663.1 EWM23463.1 - 1.3 8.9 5.7 0.16 11.8 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) PRCH PF03967.8 EWM23465.1 - 0.068 12.7 0.0 0.095 12.2 0.0 1.2 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region CAP_N PF01213.14 EWM23466.1 - 8.6 5.5 6.4 12 5.0 4.4 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal FliD_C PF07195.7 EWM23467.1 - 0.0062 15.8 0.6 0.0078 15.5 0.4 1.1 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 C-terminus Prominin PF05478.6 EWM23467.1 - 0.012 13.2 0.5 0.016 12.8 0.4 1.0 1 0 0 1 1 1 0 Prominin Nup54 PF13874.1 EWM23467.1 - 0.019 14.6 3.1 0.026 14.1 2.2 1.1 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 CCDC-167 PF15188.1 EWM23467.1 - 0.036 14.0 0.9 0.069 13.1 0.6 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 TBPIP PF07106.8 EWM23467.1 - 0.039 13.4 3.2 0.055 13.0 2.2 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) MtrG PF04210.8 EWM23467.1 - 0.085 12.5 0.2 0.2 11.3 0.1 1.6 1 1 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G Fzo_mitofusin PF04799.8 EWM23467.1 - 0.098 12.0 1.6 0.13 11.5 1.1 1.2 1 0 0 1 1 1 0 fzo-like conserved region Atg14 PF10186.4 EWM23467.1 - 1.5 7.7 5.7 1.9 7.3 4.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PhageMin_Tail PF10145.4 EWM23468.1 - 0.0018 17.9 6.2 0.0062 16.2 3.7 1.8 1 1 1 2 2 2 1 Phage-related minor tail protein RD3 PF14473.1 EWM23468.1 - 0.008 15.6 0.1 0.013 14.9 0.1 1.4 1 0 0 1 1 1 1 RD3 protein TACC PF05010.9 EWM23468.1 - 0.024 14.3 0.5 0.26 11.0 0.1 2.0 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) Drf_FH3 PF06367.11 EWM23468.1 - 0.086 12.2 0.2 0.14 11.5 0.2 1.3 1 0 0 1 1 1 0 Diaphanous FH3 Domain ScdA_N PF04405.9 EWM23468.1 - 0.11 11.8 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown function (DUF542) EcoEI_R_C PF08463.5 EWM23468.1 - 0.12 12.2 0.0 0.3 10.9 0.0 1.7 1 1 0 1 1 1 0 EcoEI R protein C-terminal HMD PF03201.11 EWM23468.1 - 0.34 10.8 1.7 0.32 10.9 0.1 1.8 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase HrpJ PF07201.6 EWM23468.1 - 0.81 9.6 5.2 0.39 10.7 1.7 1.7 2 0 0 2 2 2 0 HrpJ-like domain Methyltransf_18 PF12847.2 EWM23472.1 - 4.4e-12 46.5 0.0 8.5e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM23472.1 - 5.3e-11 42.7 0.0 9.3e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM23472.1 - 1.2e-10 41.1 0.0 2.2e-10 40.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM23472.1 - 4.6e-10 39.8 0.0 8.1e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM23472.1 - 7.1e-09 36.0 0.0 1.2e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM23472.1 - 3.4e-08 33.3 0.0 5.4e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EWM23472.1 - 1.3e-05 24.4 0.0 9.1e-05 21.7 0.0 2.1 2 0 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_26 PF13659.1 EWM23472.1 - 2.4e-05 24.3 0.1 4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EWM23472.1 - 0.00023 20.5 0.0 0.13 11.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_24 PF13578.1 EWM23472.1 - 0.036 14.8 0.0 0.071 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.6 EWM23472.1 - 0.046 13.1 0.0 0.18 11.1 0.0 2.0 2 1 0 2 2 2 0 Nodulation protein S (NodS) PrmA PF06325.8 EWM23472.1 - 0.065 12.3 0.1 0.22 10.5 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 EWM23472.1 - 0.12 11.8 0.0 0.37 10.2 0.0 1.7 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PyrBI_leader PF08052.6 EWM23473.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 PyrBI operon leader peptide GRAM PF02893.15 EWM23475.1 - 0.056 12.9 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 GRAM domain Zn_clus PF00172.13 EWM23477.1 - 4.7e-05 23.2 9.8 0.0001 22.1 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAGA-Tad1 PF12767.2 EWM23477.1 - 0.0019 17.9 9.0 0.0055 16.3 6.2 1.8 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Pex14_N PF04695.8 EWM23477.1 - 7.3 6.6 13.2 0.036 14.0 2.2 2.4 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Zip PF02535.17 EWM23477.1 - 7.4 5.4 6.2 0.3 10.0 0.2 1.6 2 0 0 2 2 2 0 ZIP Zinc transporter D123 PF07065.9 EWM23478.1 - 5.6e-57 193.0 0.0 2.6e-46 158.0 0.0 2.1 2 0 0 2 2 2 2 D123 DUF3608 PF12257.3 EWM23479.1 - 5.3e-44 150.2 0.0 2.5e-21 75.8 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3608) DUF3608 PF12257.3 EWM23480.1 - 6.8e-38 130.1 0.0 2.1e-21 76.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3608) EPTP PF03736.12 EWM23482.1 - 0.00019 21.1 0.2 2.4 7.9 0.0 4.1 4 0 0 4 4 4 3 EPTP domain DM13 PF10517.4 EWM23482.1 - 0.022 15.1 0.0 1.2 9.5 0.0 2.6 1 1 2 3 3 3 0 Electron transfer DM13 PT PF04886.7 EWM23483.1 - 1.4e-15 56.2 184.8 5e-07 28.9 11.4 7.6 2 1 3 5 5 5 4 PT repeat HSP20 PF00011.16 EWM23485.1 - 2.4e-07 30.5 0.0 5.1e-05 23.0 0.0 2.6 3 0 0 3 3 3 2 Hsp20/alpha crystallin family DUF1441 PF07278.6 EWM23485.1 - 0.015 14.9 0.1 0.023 14.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1441) DUF4407 PF14362.1 EWM23485.1 - 0.031 13.2 0.8 0.04 12.8 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_S49_N PF08496.5 EWM23485.1 - 0.94 9.2 3.6 1.6 8.5 2.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Atg14 PF10186.4 EWM23485.1 - 1.3 7.8 4.5 1.8 7.4 3.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 2OG-FeII_Oxy_5 PF13759.1 EWM23486.1 - 0.042 14.1 0.0 0.24 11.7 0.0 2.1 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase His_Phos_2 PF00328.17 EWM23488.1 - 2.2e-14 53.5 0.0 8.5e-13 48.3 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF3463 PF11946.3 EWM23489.1 - 0.061 12.9 0.0 0.091 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3463) Carboxyl_trans PF01039.17 EWM23491.1 - 1.5e-149 498.5 0.0 1.9e-149 498.2 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 EWM23491.1 - 2.6e-05 23.5 0.1 0.0056 15.9 0.0 2.2 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) AF0941-like PF14591.1 EWM23494.1 - 0.063 13.3 0.6 0.21 11.6 0.0 2.1 2 1 1 3 3 3 0 AF0941-like TFIIF_beta PF02270.10 EWM23495.1 - 1.6e-18 67.4 0.0 3.4e-18 66.4 0.0 1.4 1 1 0 1 1 1 1 Transcription initiation factor IIF, beta subunit Myotub-related PF06602.9 EWM23497.1 - 1.2e-74 251.2 0.0 1.5e-74 250.9 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 EWM23497.1 - 0.0016 18.7 0.5 0.0041 17.3 0.2 1.7 1 1 1 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EWM23497.1 - 0.012 14.9 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.15 EWM23497.1 - 0.11 12.0 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain CAP PF00188.21 EWM23498.1 - 3.3e-07 30.8 1.5 3.3e-07 30.8 1.0 2.1 2 1 0 2 2 2 1 Cysteine-rich secretory protein family PH PF00169.24 EWM23501.1 - 0.0059 16.7 0.0 0.0093 16.1 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EWM23501.1 - 0.013 15.7 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Beta-lactamase PF00144.19 EWM23503.1 - 0.011 14.8 0.0 0.011 14.8 0.0 1.0 1 0 0 1 1 1 0 Beta-lactamase Beta-lactamase PF00144.19 EWM23504.1 - 8.3e-23 80.9 0.0 9.7e-23 80.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase TPPK_C PF12555.3 EWM23504.1 - 0.056 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal HTH_15 PF12324.3 EWM23506.1 - 0.082 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase NAD_kinase PF01513.16 EWM23511.1 - 2.4e-55 187.3 0.0 3.2e-55 186.9 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DUF204 PF02659.10 EWM23513.1 - 0.043 13.9 1.5 0.043 13.9 1.1 1.7 1 1 1 2 2 2 0 Domain of unknown function DUF MBOAT PF03062.14 EWM23514.1 - 4.7e-20 71.9 9.8 6e-20 71.6 6.8 1.0 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EWM23514.1 - 7.3e-06 25.9 3.9 1.3e-05 25.2 2.7 1.3 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family ACBP PF00887.14 EWM23515.1 - 2.4e-19 68.7 0.0 5e-19 67.7 0.0 1.5 2 0 0 2 2 2 1 Acyl CoA binding protein Abhydrolase_6 PF12697.2 EWM23516.1 - 1.9e-06 27.9 0.0 1.9e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EWM23516.1 - 0.0019 17.8 0.0 0.0024 17.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S10 PF00450.17 EWM23516.1 - 0.0087 15.2 0.0 0.01 15.0 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase ClpS PF02617.12 EWM23517.1 - 2.7e-08 33.4 0.0 3.6e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS ExbD PF02472.11 EWM23517.1 - 0.029 14.3 0.3 0.079 12.9 0.1 1.8 1 1 0 1 1 1 0 Biopolymer transport protein ExbD/TolR Abhydrolase_6 PF12697.2 EWM23518.1 - 1.3e-08 34.9 0.2 2.2e-08 34.2 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydro_lipase PF04083.11 EWM23518.1 - 0.013 14.8 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Abhydrolase_5 PF12695.2 EWM23518.1 - 0.018 14.8 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.11 EWM23520.1 - 7.1e-21 74.2 24.4 8.5e-21 74.0 16.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.8 EWM23520.1 - 0.0017 16.5 8.8 0.0023 16.1 6.1 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector LacY_symp PF01306.14 EWM23520.1 - 0.005 15.4 6.3 0.42 9.1 0.1 2.0 2 0 0 2 2 2 2 LacY proton/sugar symporter Sugar_tr PF00083.19 EWM23520.1 - 0.016 13.8 11.1 0.008 14.8 2.8 2.1 1 1 0 2 2 2 0 Sugar (and other) transporter MFS_1_like PF12832.2 EWM23520.1 - 0.016 14.9 2.1 0.016 14.9 1.4 1.7 2 0 0 2 2 2 0 MFS_1 like family OppC_N PF12911.2 EWM23520.1 - 0.078 12.3 1.8 0.19 11.1 1.3 1.7 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C HpcH_HpaI PF03328.9 EWM23523.1 - 2e-15 56.2 0.0 2.7e-15 55.8 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family His_Phos_1 PF00300.17 EWM23524.1 - 1.5e-07 31.6 0.0 1.7e-07 31.4 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SNARE_assoc PF09335.6 EWM23526.1 - 0.065 13.4 0.1 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 SNARE associated Golgi protein SP2 PF03014.9 EWM23527.1 - 0.47 8.2 2.8 0.19 9.5 0.5 1.3 2 0 0 2 2 2 0 Structural protein 2 DPM3 PF08285.6 EWM23529.1 - 1.8e-20 72.5 0.0 2.7e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Adenylsucc_synt PF00709.16 EWM23530.1 - 8.7e-13 47.6 0.2 1.2e-12 47.2 0.2 1.2 1 0 0 1 1 1 1 Adenylosuccinate synthetase Hyccin PF09790.4 EWM23531.1 - 0.35 9.6 1.1 0.44 9.3 0.7 1.1 1 0 0 1 1 1 0 Hyccin Thioredoxin PF00085.15 EWM23532.1 - 8e-22 76.8 0.0 1.1e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 EWM23532.1 - 9.1e-06 25.6 0.0 1.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.1 EWM23532.1 - 9.1e-05 22.5 0.0 0.0023 18.0 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EWM23532.1 - 0.00071 19.7 0.1 0.007 16.5 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EWM23532.1 - 0.0017 18.0 0.0 0.0028 17.3 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EWM23532.1 - 0.0031 17.0 0.0 0.0054 16.2 0.0 1.4 1 0 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.1 EWM23532.1 - 0.0091 15.5 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin PA PF02225.17 EWM23533.1 - 8.9e-08 31.7 0.0 3.7e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 PA domain DDHD PF02862.12 EWM23533.1 - 0.13 12.0 4.9 0.2 11.4 3.4 1.2 1 0 0 1 1 1 0 DDHD domain CobT PF06213.7 EWM23533.1 - 0.39 9.7 34.0 0.6 9.1 23.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SpoIIIAH PF12685.2 EWM23533.1 - 0.57 9.6 11.3 0.83 9.1 7.8 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein BUD22 PF09073.5 EWM23533.1 - 0.63 9.0 23.3 0.9 8.5 16.1 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 EWM23533.1 - 0.71 7.7 32.4 0.91 7.3 22.4 1.0 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EWM23533.1 - 2 6.8 30.1 2.6 6.4 20.9 1.1 1 0 0 1 1 1 0 Daxx Family CENP-T PF15511.1 EWM23533.1 - 4.3 6.4 19.3 1 8.5 10.9 1.7 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T SAPS PF04499.10 EWM23533.1 - 6.8 5.1 9.6 9.5 4.7 6.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1510 PF07423.6 EWM23533.1 - 9.7 5.4 24.6 15 4.9 17.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF972 PF06156.8 EWM23536.1 - 0.0028 17.9 0.4 0.0041 17.4 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF972) DUF3584 PF12128.3 EWM23536.1 - 0.011 13.1 0.2 0.014 12.7 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Leu_zip PF15294.1 EWM23536.1 - 0.039 13.0 0.3 0.046 12.8 0.2 1.0 1 0 0 1 1 1 0 Leucine zipper Rab5-bind PF09311.6 EWM23536.1 - 0.076 12.9 1.7 0.1 12.4 1.2 1.1 1 0 0 1 1 1 0 Rabaptin-like protein TMF_TATA_bd PF12325.3 EWM23536.1 - 0.082 12.6 1.8 0.14 11.8 1.2 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding IncA PF04156.9 EWM23536.1 - 0.14 11.7 1.3 0.18 11.3 0.9 1.1 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 EWM23536.1 - 0.2 11.1 2.3 2.6 7.5 1.9 2.1 1 1 1 2 2 2 0 Septum formation initiator Prefoldin_2 PF01920.15 EWM23536.1 - 0.3 10.8 4.6 2.1 8.1 0.1 2.1 1 1 0 2 2 2 0 Prefoldin subunit DUF904 PF06005.7 EWM23536.1 - 0.48 10.7 5.0 3.7 7.9 3.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF904) ADIP PF11559.3 EWM23536.1 - 0.68 9.8 3.9 0.92 9.4 2.7 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding RecA PF00154.16 EWM23537.1 - 1.2e-34 119.9 0.0 3.5e-33 115.0 0.0 2.0 2 0 0 2 2 2 2 recA bacterial DNA recombination protein KaiC PF06745.8 EWM23537.1 - 0.0078 15.3 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 KaiC Glyco_hydro_47 PF01532.15 EWM23538.1 - 1.1e-32 113.3 0.0 1.5e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 SOBP PF15279.1 EWM23538.1 - 0.06 13.7 4.8 0.08 13.3 3.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4614 PF15391.1 EWM23538.1 - 4.1 7.1 17.8 6.2 6.5 12.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) ATP-grasp_4 PF13535.1 EWM23541.1 - 1.2e-19 70.7 0.0 1e-16 61.2 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 EWM23541.1 - 0.00062 19.3 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_Ter PF15632.1 EWM23541.1 - 0.0073 15.0 0.0 0.041 12.6 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 EWM23541.1 - 0.013 15.3 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain DUF566 PF04484.7 EWM23541.1 - 4.1 6.8 5.5 10 5.5 3.8 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF566) RHS PF03527.9 EWM23542.1 - 0.13 12.0 0.2 0.22 11.3 0.2 1.3 1 0 0 1 1 1 0 RHS protein RHS PF03527.9 EWM23543.1 - 0.065 13.0 1.1 0.25 11.1 0.2 2.1 2 0 0 2 2 2 0 RHS protein SKG6 PF08693.5 EWM23544.1 - 0.44 9.9 2.3 0.61 9.4 0.0 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain CSD PF00313.17 EWM23545.1 - 1.6e-23 82.2 0.5 1.9e-23 81.9 0.3 1.1 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.6 EWM23545.1 - 2.5e-06 26.8 0.1 3.9e-06 26.2 0.1 1.5 1 1 0 1 1 1 1 Ribonuclease B OB domain Rho_RNA_bind PF07497.7 EWM23545.1 - 0.08 12.5 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Rho termination factor, RNA-binding domain Fer2 PF00111.22 EWM23547.1 - 3.1e-09 36.4 0.5 4.7e-09 35.8 0.4 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DnaJ_CXXCXGXG PF00684.14 EWM23548.1 - 0.011 15.7 15.5 0.2 11.7 10.8 2.9 1 1 1 2 2 2 0 DnaJ central domain zf-RING_3 PF14369.1 EWM23548.1 - 0.12 12.3 6.0 2.5 8.1 0.1 3.5 3 1 1 4 4 4 0 zinc-finger zf-rbx1 PF12678.2 EWM23548.1 - 0.15 12.2 4.4 8.7 6.5 3.0 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger A2L_zn_ribbon PF08792.5 EWM23548.1 - 0.64 9.5 10.0 9.4 5.8 1.1 3.2 2 1 1 3 3 3 0 A2L zinc ribbon domain DUF1356 PF07092.7 EWM23548.1 - 5.9 6.0 11.1 14 4.7 0.1 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF1356) IBR PF01485.16 EWM23548.1 - 7.9 6.4 12.0 4.5e+02 0.8 8.3 2.3 1 1 0 1 1 1 0 IBR domain Na_H_Exchanger PF00999.16 EWM23549.1 - 5e-63 212.8 44.8 7.1e-63 212.3 31.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family S4 PF01479.20 EWM23552.1 - 4e-12 45.3 0.0 1.6e-11 43.4 0.0 2.0 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.14 EWM23552.1 - 2.3e-09 37.5 1.6 3.3e-09 37.0 1.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain AKNA PF12443.3 EWM23552.1 - 0.11 12.4 2.3 0.15 12.1 1.0 1.7 1 1 0 1 1 1 0 AT-hook-containing transcription factor Ribosomal_S4 PF00163.14 EWM23553.1 - 1.1e-09 38.4 1.6 1.6e-09 38.0 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EWM23553.1 - 2.1e-08 33.4 0.0 9.4e-08 31.3 0.0 2.0 2 0 0 2 2 2 1 S4 domain AKNA PF12443.3 EWM23553.1 - 0.08 12.9 2.6 0.09 12.8 1.0 1.7 1 1 1 2 2 2 0 AT-hook-containing transcription factor Wyosine_form PF08608.7 EWM23554.1 - 1.7e-21 76.0 0.1 2.6e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Wyosine base formation Wyosine_form PF08608.7 EWM23555.1 - 6e-18 64.7 0.1 3.7e-12 46.1 0.0 2.3 2 0 0 2 2 2 2 Wyosine base formation LRR_6 PF13516.1 EWM23557.1 - 4.6e-34 112.6 0.4 0.0024 17.7 0.0 13.0 14 0 0 14 14 14 8 Leucine Rich repeat LRR_4 PF12799.2 EWM23557.1 - 1.1e-15 56.8 0.0 0.021 14.4 0.0 8.0 5 3 4 9 9 9 6 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EWM23557.1 - 1.5e-13 48.5 0.1 29 5.4 0.0 10.8 11 0 0 11 11 11 0 Leucine rich repeat LRR_1 PF00560.28 EWM23557.1 - 9.4e-13 46.3 0.8 11 6.5 0.0 10.1 11 2 0 11 11 11 2 Leucine Rich Repeat LRR_8 PF13855.1 EWM23557.1 - 8.4e-07 28.6 7.0 0.99 9.2 0.2 8.3 5 3 2 7 7 7 4 Leucine rich repeat UPF0262 PF06793.7 EWM23557.1 - 0.014 15.1 0.1 0.97 9.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0262) WD40 PF00400.27 EWM23559.1 - 3.4e-08 33.0 0.3 1.1e-07 31.4 0.2 1.9 2 0 0 2 2 2 1 WD domain, G-beta repeat OPA3 PF07047.7 EWM23560.1 - 1.3e-27 96.1 0.2 1.3e-27 96.1 0.2 2.5 2 0 0 2 2 2 1 Optic atrophy 3 protein (OPA3) NOA36 PF06524.7 EWM23560.1 - 1.6 7.8 4.7 2.8 7.1 3.2 1.3 1 0 0 1 1 1 0 NOA36 protein Myc_N PF01056.13 EWM23560.1 - 6.1 5.9 8.3 17 4.4 5.7 1.8 1 0 0 1 1 1 0 Myc amino-terminal region Ribosomal_60s PF00428.14 EWM23560.1 - 6.4 7.2 19.8 3.9 7.9 9.1 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein DDHD PF02862.12 EWM23560.1 - 8.9 6.0 7.5 32 4.2 5.2 2.0 1 1 0 1 1 1 0 DDHD domain Seipin PF06775.9 EWM23562.1 - 3.3e-40 137.7 0.0 5.5e-40 137.0 0.0 1.3 1 1 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) PDZ PF00595.19 EWM23563.1 - 5.4e-08 32.8 0.0 0.27 11.4 0.0 4.2 4 0 0 4 4 4 3 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EWM23563.1 - 0.016 15.1 0.0 11 6.0 0.0 3.3 3 0 0 3 3 3 0 PDZ domain Mito_carr PF00153.22 EWM23564.1 - 1.9e-08 33.8 0.1 2.5e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial carrier protein DEC-1_N PF04625.8 EWM23565.1 - 0.81 8.2 9.9 1.6 7.3 6.9 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region SNARE_assoc PF09335.6 EWM23566.1 - 1.3e-18 67.4 10.0 3.4e-18 66.0 6.9 1.7 1 0 0 1 1 1 1 SNARE associated Golgi protein RseC_MucC PF04246.7 EWM23566.1 - 0.72 9.4 9.3 2.8 7.5 0.2 2.5 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Phageshock_PspD PF09584.5 EWM23566.1 - 5.6 6.7 10.7 0.46 10.2 0.2 3.2 3 0 0 3 3 3 0 Phage shock protein PspD (Phageshock_PspD) cobW PF02492.14 EWM23567.1 - 6.5e-36 123.4 0.0 9.1e-36 122.9 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EWM23567.1 - 3.9e-05 23.2 0.0 0.00074 19.1 0.0 2.5 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain AAA_33 PF13671.1 EWM23567.1 - 0.013 15.4 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain LRR_4 PF12799.2 EWM23568.1 - 8.2e-06 25.3 7.1 0.011 15.3 0.0 3.4 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EWM23568.1 - 0.00098 18.8 9.3 0.034 13.9 3.1 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_9 PF14580.1 EWM23568.1 - 0.0048 16.4 1.0 2.2 7.8 0.0 2.3 2 0 0 2 2 2 2 Leucine-rich repeat DUF4407 PF14362.1 EWM23569.1 - 0.0055 15.7 2.7 0.0081 15.1 1.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Ribosomal_S13_N PF08069.7 EWM23570.1 - 7.4e-30 102.5 0.4 1.4e-29 101.7 0.1 1.6 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EWM23570.1 - 7.2e-16 57.7 1.0 1.2e-15 57.0 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 Ribosomal_L21e PF01157.13 EWM23571.1 - 2.8e-40 136.1 2.0 5.4e-40 135.2 1.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L21e DUF883 PF05957.8 EWM23572.1 - 0.33 11.3 6.3 8.4 6.8 1.0 2.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) GalKase_gal_bdg PF10509.4 EWM23574.1 - 2.1e-22 78.1 0.1 2.8e-22 77.7 0.1 1.2 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 EWM23575.1 - 3.5e-06 27.1 0.0 5e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 GHMP kinases C terminal TPPK_C PF12555.3 EWM23575.1 - 1.1 9.0 5.8 2 8.2 4.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal La PF05383.12 EWM23576.1 - 5.5e-05 22.8 0.0 8.5e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 La domain DNA_photolyase PF00875.13 EWM23577.1 - 1.4e-15 57.4 0.0 1.8e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 DNA photolyase MATH PF00917.21 EWM23578.1 - 0.016 15.4 0.1 1.9 8.7 0.0 2.1 1 1 1 2 2 2 0 MATH domain DUF4451 PF14616.1 EWM23578.1 - 0.042 13.6 0.1 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4451) HlyIII PF03006.15 EWM23580.1 - 8e-14 51.5 22.3 1e-13 51.2 15.5 1.1 1 0 0 1 1 1 1 Haemolysin-III related Hum_adeno_E3A PF05393.6 EWM23580.1 - 1.1 9.0 4.1 3.9 7.2 0.1 2.5 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein PALP PF00291.20 EWM23581.1 - 1.1e-38 133.2 2.0 1.5e-31 109.8 0.1 2.2 1 1 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme Myc_N PF01056.13 EWM23581.1 - 0.3 10.2 2.5 0.18 10.9 0.5 1.5 2 0 0 2 2 2 0 Myc amino-terminal region Bot1p PF12298.3 EWM23581.1 - 0.4 10.6 3.0 0.67 9.8 2.1 1.2 1 0 0 1 1 1 0 Eukaryotic mitochondrial regulator protein Elf1 PF05129.8 EWM23583.1 - 1.7e-23 82.0 7.4 2e-23 81.8 5.2 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-CHY PF05495.7 EWM23583.1 - 0.097 12.8 4.3 0.12 12.5 3.0 1.3 1 0 0 1 1 1 0 CHY zinc finger Prim_Zn_Ribbon PF08273.7 EWM23583.1 - 0.18 11.9 1.7 0.49 10.4 0.0 2.3 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase C1_4 PF07975.7 EWM23583.1 - 7.7 6.6 8.6 0.43 10.6 0.7 2.2 1 1 1 2 2 2 0 TFIIH C1-like domain zf-C3HC4_4 PF15227.1 EWM23583.1 - 9 6.2 9.8 6.8 6.6 2.4 2.9 1 1 2 3 3 3 0 zinc finger of C3HC4-type, RING Methyltransf_16 PF10294.4 EWM23585.1 - 1.3e-21 76.8 0.0 3.4e-21 75.4 0.0 1.6 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EWM23585.1 - 0.00034 21.1 0.0 0.00061 20.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EWM23585.1 - 0.0057 15.8 0.0 0.0083 15.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EWM23585.1 - 0.016 14.5 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 EWM23585.1 - 0.04 13.9 0.1 0.074 13.0 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain MutS_I PF01624.15 EWM23586.1 - 4.3e-23 81.4 0.0 7e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 MutS domain I SR-25 PF10500.4 EWM23586.1 - 0.0064 15.9 15.7 0.0064 15.9 10.9 2.1 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DGF-1_C PF11040.3 EWM23586.1 - 0.14 12.0 0.0 0.14 12.0 0.0 3.0 2 1 1 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF1637 PF07847.7 EWM23588.1 - 5.6e-42 143.3 0.0 7.9e-42 142.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) SR-25 PF10500.4 EWM23588.1 - 0.00079 18.9 11.3 0.00079 18.9 7.8 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein CDO_I PF05995.7 EWM23588.1 - 0.046 12.9 0.0 0.087 11.9 0.0 1.4 1 0 0 1 1 1 0 Cysteine dioxygenase type I CAF-1_p150 PF11600.3 EWM23588.1 - 0.28 10.5 6.2 0.82 9.0 4.3 1.7 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4228 PF14009.1 EWM23588.1 - 0.37 10.9 3.8 18 5.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) FRG2 PF15315.1 EWM23588.1 - 1.2 9.1 9.3 2.4 8.1 6.4 1.4 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 DUF515 PF04415.7 EWM23588.1 - 3.9 5.6 8.1 5.4 5.1 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF2039 PF10217.4 EWM23590.1 - 1.8e-28 98.4 7.6 2.4e-28 97.9 5.3 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) Paired_CXXCH_1 PF09699.5 EWM23590.1 - 0.0068 15.8 0.5 0.0068 15.8 0.4 2.8 2 1 0 2 2 2 1 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrome_C554 PF13435.1 EWM23590.1 - 0.012 15.6 13.4 0.028 14.4 4.4 2.1 1 1 1 2 2 2 0 Cytochrome c554 and c-prime Cytochrome_C7 PF14522.1 EWM23590.1 - 0.024 14.2 11.3 0.058 13.0 7.6 1.7 1 1 0 1 1 1 0 Cytochrome c7 DUF2256 PF10013.4 EWM23590.1 - 0.069 12.9 1.0 0.069 12.9 0.7 2.2 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) FYVE_2 PF02318.11 EWM23590.1 - 0.19 11.6 4.6 0.32 10.8 3.2 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Cytochrom_c3_2 PF14537.1 EWM23590.1 - 0.37 11.1 11.2 1.3 9.4 7.2 2.0 1 1 1 2 2 2 0 Cytochrome c3 DUF2161 PF09929.4 EWM23590.1 - 0.81 9.6 3.3 4.9 7.1 0.1 2.4 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2161) Cript PF10235.4 EWM23590.1 - 3.6 8.0 11.7 22 5.5 8.1 2.0 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT zinc-ribbons_6 PF07191.7 EWM23590.1 - 8.7 6.2 11.6 9.8 6.0 4.5 2.2 1 1 1 2 2 2 0 zinc-ribbons DUF2039 PF10217.4 EWM23591.1 - 2e-28 98.2 7.6 2.9e-28 97.7 5.3 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) Paired_CXXCH_1 PF09699.5 EWM23591.1 - 0.0076 15.7 0.5 0.0076 15.7 0.4 2.8 2 1 0 2 2 2 1 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrome_C554 PF13435.1 EWM23591.1 - 0.016 15.2 14.1 0.053 13.5 4.8 2.2 1 1 1 2 2 2 0 Cytochrome c554 and c-prime Cytochrome_C7 PF14522.1 EWM23591.1 - 0.028 14.0 11.4 0.068 12.8 7.8 1.8 1 1 0 1 1 1 0 Cytochrome c7 DUF2256 PF10013.4 EWM23591.1 - 0.076 12.7 1.0 0.076 12.7 0.7 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) FYVE_2 PF02318.11 EWM23591.1 - 0.24 11.2 4.8 0.42 10.5 3.3 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Cytochrom_c3_2 PF14537.1 EWM23591.1 - 0.28 11.5 10.7 0.85 9.9 6.7 2.1 1 1 1 2 2 2 0 Cytochrome c3 DUF2161 PF09929.4 EWM23591.1 - 1.1 9.2 3.5 5.9 6.8 0.1 2.4 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2161) Cript PF10235.4 EWM23591.1 - 4.8 7.6 12.1 29 5.0 8.3 2.1 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT DUF2039 PF10217.4 EWM23592.1 - 2.1e-28 98.1 7.6 2.9e-28 97.7 5.3 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) Cytochrome_C554 PF13435.1 EWM23592.1 - 0.0033 17.4 13.4 0.0094 16.0 3.9 2.1 1 1 1 2 2 2 2 Cytochrome c554 and c-prime Paired_CXXCH_1 PF09699.5 EWM23592.1 - 0.0077 15.7 0.5 0.0077 15.7 0.4 2.8 2 1 0 2 2 2 1 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrome_C7 PF14522.1 EWM23592.1 - 0.033 13.8 11.5 0.075 12.6 7.9 1.7 1 1 0 1 1 1 0 Cytochrome c7 PAS PF00989.19 EWM23592.1 - 0.038 13.7 0.0 0.082 12.6 0.0 1.5 1 0 0 1 1 1 0 PAS fold DUF2256 PF10013.4 EWM23592.1 - 0.076 12.7 1.0 0.076 12.7 0.7 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) FYVE_2 PF02318.11 EWM23592.1 - 0.25 11.2 4.8 0.43 10.4 3.3 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger Cytochrom_c3_2 PF14537.1 EWM23592.1 - 0.33 11.3 10.8 0.083 13.2 4.3 2.1 1 1 1 2 2 2 0 Cytochrome c3 DUF2161 PF09929.4 EWM23592.1 - 0.98 9.3 3.4 5.9 6.8 0.3 2.5 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2161) Cript PF10235.4 EWM23592.1 - 4.4 7.7 11.9 3.3 8.1 5.7 2.1 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT HMG_box PF00505.14 EWM23593.1 - 2.4e-14 53.3 1.7 2.4e-14 53.3 1.2 2.5 2 0 0 2 2 2 1 HMG (high mobility group) box CBFD_NFYB_HMF PF00808.18 EWM23593.1 - 1.5e-13 50.5 0.5 5.4e-13 48.8 0.1 2.2 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HMG_box_2 PF09011.5 EWM23593.1 - 2.4e-12 47.0 3.2 2.4e-12 47.0 2.2 2.7 3 0 0 3 3 3 1 HMG-box domain Histone PF00125.19 EWM23593.1 - 0.0031 17.5 0.1 0.0064 16.5 0.1 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Nop10p PF04135.7 EWM23594.1 - 2.6e-06 27.0 0.0 3.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Cystatin PF00031.16 EWM23596.1 - 2.3e-05 24.4 0.0 5.8e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Cystatin domain DUF2984 PF11203.3 EWM23596.1 - 0.33 11.0 3.0 0.56 10.3 2.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2984) Cyclin_N PF00134.18 EWM23597.1 - 5.7e-31 106.7 0.2 9.2e-31 106.0 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EWM23597.1 - 0.0025 17.7 1.3 0.0046 16.8 0.2 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain Pex2_Pex12 PF04757.9 EWM23598.1 - 5e-17 62.0 0.0 1.6e-16 60.4 0.0 1.7 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 EWM23598.1 - 3.2e-10 39.6 12.8 5.5e-10 38.9 8.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EWM23598.1 - 8.3e-10 38.5 13.6 1.6e-09 37.6 9.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EWM23598.1 - 8.9e-09 34.8 14.8 1.5e-08 34.1 10.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EWM23598.1 - 1e-07 31.4 12.6 1.8e-07 30.7 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EWM23598.1 - 1.6e-06 27.7 10.7 3e-06 26.8 7.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EWM23598.1 - 0.00039 20.2 12.8 0.00072 19.3 8.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EWM23598.1 - 0.0011 18.9 7.1 0.002 18.1 4.9 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger DUF1183 PF06682.7 EWM23598.1 - 0.049 13.2 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) zf-RING_UBOX PF13445.1 EWM23598.1 - 0.05 13.3 10.1 0.13 12.0 7.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.1 EWM23598.1 - 0.76 9.6 6.4 1.4 8.7 4.4 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 EWM23598.1 - 5.8 6.5 11.5 15 5.2 8.0 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 PrmA PF06325.8 EWM23599.1 - 4.6e-11 42.3 2.3 8.1e-11 41.5 1.0 1.8 1 1 1 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 EWM23599.1 - 7.1e-10 38.6 0.0 1.2e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM23599.1 - 1.9e-08 34.8 0.0 3.9e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM23599.1 - 4.6e-08 33.0 0.0 1.4e-07 31.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EWM23599.1 - 6.8e-07 28.8 0.1 1.1e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 EWM23599.1 - 1.5e-06 28.5 0.0 3.1e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 EWM23599.1 - 3e-05 23.1 0.0 7.4e-05 21.8 0.0 1.5 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Ubie_methyltran PF01209.13 EWM23599.1 - 0.00015 20.9 0.1 0.00023 20.3 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Met_10 PF02475.11 EWM23599.1 - 0.00027 20.5 0.1 0.00048 19.7 0.1 1.4 1 0 0 1 1 1 1 Met-10+ like-protein CMAS PF02353.15 EWM23599.1 - 0.00038 19.6 1.0 0.00038 19.6 0.7 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.6 EWM23599.1 - 0.0013 17.5 0.1 0.0019 16.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.1 EWM23599.1 - 0.0018 18.0 0.0 0.0028 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM23599.1 - 0.0043 17.4 0.0 0.013 15.8 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EWM23599.1 - 0.0082 15.6 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase UPF0020 PF01170.13 EWM23599.1 - 0.012 15.2 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 RrnaAD PF00398.15 EWM23599.1 - 0.017 14.1 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FtsJ PF01728.14 EWM23599.1 - 0.026 14.5 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase OpuAC PF04069.7 EWM23599.1 - 0.027 13.8 0.1 0.048 13.0 0.1 1.4 1 0 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system PCMT PF01135.14 EWM23599.1 - 0.027 13.9 0.2 0.052 13.0 0.1 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.1 EWM23599.1 - 0.038 14.8 0.1 0.099 13.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain HlyC PF02794.11 EWM23599.1 - 0.082 12.5 0.1 0.26 10.9 0.0 1.8 2 0 0 2 2 2 0 RTX toxin acyltransferase family FAD_binding_4 PF01565.18 EWM23600.1 - 3.5e-20 71.9 2.0 4.9e-20 71.4 1.4 1.2 1 0 0 1 1 1 1 FAD binding domain DSPc PF00782.15 EWM23603.1 - 1.7e-27 95.6 0.0 2.5e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EWM23603.1 - 0.0062 15.8 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF3889 PF13028.1 EWM23603.1 - 0.086 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3889) DSPc PF00782.15 EWM23604.1 - 1.7e-27 95.6 0.0 2.5e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EWM23604.1 - 0.0062 15.8 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF3889 PF13028.1 EWM23604.1 - 0.086 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3889) CppA_N PF14506.1 EWM23605.1 - 0.037 13.6 0.1 0.39 10.3 0.0 2.1 2 0 0 2 2 2 0 CppA N-terminal IBN_N PF03810.14 EWM23606.1 - 6.1e-07 29.2 0.1 1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain PPI_Ypi1 PF07491.6 EWM23608.1 - 1.3e-24 85.5 2.0 2.4e-24 84.6 1.4 1.5 1 0 0 1 1 1 1 Protein phosphatase inhibitor DUF775 PF05603.7 EWM23609.1 - 5.5e-37 127.2 0.0 6.3e-36 123.8 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF775) zf-RING_2 PF13639.1 EWM23610.1 - 8.1e-14 51.1 8.8 1.4e-13 50.4 6.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EWM23610.1 - 0.0001 22.3 3.3 0.00019 21.4 2.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EWM23610.1 - 0.001 19.0 7.9 0.0016 18.4 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EWM23610.1 - 0.0011 18.6 6.2 0.0017 18.0 4.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EWM23610.1 - 0.038 13.7 6.1 0.058 13.1 4.3 1.3 1 0 0 1 1 1 0 zinc-RING finger domain Thaumatin PF00314.12 EWM23613.1 - 7.4e-08 32.1 1.6 1.1e-07 31.6 1.1 1.1 1 0 0 1 1 1 1 Thaumatin family PH PF00169.24 EWM23615.1 - 6.8e-05 23.0 0.0 9.4e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 PH domain Stb3 PF10330.4 EWM23615.1 - 0.054 13.1 0.2 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Putative Sin3 binding protein BK_channel_a PF03493.13 EWM23619.1 - 5.7e-19 67.9 0.0 1.1e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.11 EWM23619.1 - 3.2e-12 45.9 8.3 3.2e-12 45.9 5.8 2.2 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.26 EWM23619.1 - 6e-06 25.6 19.9 1.1e-05 24.8 11.6 2.6 2 1 0 2 2 2 1 Ion transport protein Peptidase_A24 PF01478.13 EWM23619.1 - 0.13 12.3 4.3 0.12 12.5 1.5 2.1 2 0 0 2 2 2 0 Type IV leader peptidase family Complex1_LYR PF05347.10 EWM23620.1 - 6e-09 35.5 0.2 8.7e-09 35.0 0.1 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EWM23620.1 - 2e-05 24.6 0.1 2.9e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like PseudoU_synth_1 PF01416.15 EWM23621.1 - 2.7e-24 85.6 0.0 6.6e-16 58.6 0.0 2.9 2 1 0 2 2 2 2 tRNA pseudouridine synthase NAD_binding_10 PF13460.1 EWM23622.1 - 9.6e-18 64.8 0.0 2e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EWM23622.1 - 2.9e-08 33.4 0.1 5.7e-08 32.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EWM23622.1 - 1.6e-07 30.3 0.0 3.5e-06 25.9 0.0 2.1 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EWM23622.1 - 7.2e-05 22.1 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 EWM23622.1 - 0.0036 16.2 0.2 1.4 7.6 0.1 2.8 2 1 0 2 2 2 2 RmlD substrate binding domain NAD_binding_4 PF07993.7 EWM23622.1 - 0.0082 15.0 0.0 0.52 9.2 0.0 2.8 2 1 0 2 2 2 1 Male sterility protein ELFV_dehydrog PF00208.16 EWM23622.1 - 0.07 12.6 0.8 0.17 11.4 0.1 1.7 1 1 1 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Antimicrobial14 PF08109.6 EWM23622.1 - 0.087 12.6 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 Lactocin 705 family DUF4315 PF14193.1 EWM23623.1 - 1.4 8.9 9.0 1 9.3 1.6 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4315) DUF2562 PF10814.3 EWM23624.1 - 0.0052 16.7 0.1 0.013 15.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2562) DUF3382 PF11862.3 EWM23624.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) Y_phosphatase3 PF13350.1 EWM23625.1 - 0.22 11.7 3.3 0.51 10.5 2.3 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family Aldo_ket_red PF00248.16 EWM23626.1 - 2e-52 177.7 0.0 2.6e-52 177.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family TAT_signal PF10518.4 EWM23626.1 - 0.057 13.4 0.9 0.057 13.4 0.7 3.1 3 0 0 3 3 3 0 TAT (twin-arginine translocation) pathway signal sequence RAP1 PF07218.6 EWM23627.1 - 8.5 4.3 4.5 13 3.6 3.1 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Methyltransf_11 PF08241.7 EWM23628.1 - 7.8e-11 42.3 0.0 2e-10 41.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM23628.1 - 6.8e-09 35.6 0.0 1e-08 35.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM23628.1 - 1.1e-07 31.5 0.0 1.7e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM23628.1 - 5.6e-07 29.9 0.0 3.5e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EWM23628.1 - 1.4e-06 27.5 0.0 2.9e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EWM23628.1 - 0.0062 16.8 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM23628.1 - 0.068 13.2 0.0 0.33 10.9 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain KH_1 PF00013.24 EWM23629.1 - 1.4e-43 146.2 12.5 4e-15 55.2 2.4 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EWM23629.1 - 1.9e-29 100.7 18.8 1.3e-09 37.4 0.6 3.9 4 0 0 4 4 4 3 KH domain KH_2 PF07650.12 EWM23629.1 - 4.4e-16 58.2 3.7 6.8e-07 28.7 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EWM23629.1 - 1.6e-08 34.0 3.3 0.05 13.2 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EWM23629.1 - 0.0015 18.2 3.6 5.7 6.8 0.0 3.3 3 0 0 3 3 3 2 NusA-like KH domain Cullin PF00888.17 EWM23630.1 - 1.2e-51 175.9 0.0 8.9e-51 173.1 0.0 2.2 1 1 0 1 1 1 1 Cullin family DUF1995 PF09353.5 EWM23631.1 - 1.2e-25 90.4 0.0 1.8e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) PAP_fibrillin PF04755.7 EWM23631.1 - 0.0016 18.1 0.0 0.3 10.7 0.0 2.4 1 1 0 1 1 1 1 PAP_fibrillin BsuBI_PstI_RE PF06616.6 EWM23631.1 - 0.088 11.6 0.0 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease C-terminus TPR_16 PF13432.1 EWM23632.1 - 0.11 13.2 9.0 1 10.0 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EWM23632.1 - 0.11 13.2 12.5 0.21 12.2 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat CRAL_TRIO PF00650.15 EWM23633.1 - 7.8e-30 103.4 0.0 1e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EWM23633.1 - 1.9e-12 47.3 0.0 3.3e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Pkinase PF00069.20 EWM23634.1 - 2.6e-73 246.3 0.0 3.1e-73 246.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM23634.1 - 3.2e-32 111.6 0.0 4e-32 111.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EWM23634.1 - 0.0003 19.8 0.0 0.0038 16.2 0.0 2.1 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EWM23634.1 - 0.00089 19.0 0.0 0.008 15.9 0.0 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EWM23634.1 - 0.022 13.8 0.0 0.046 12.7 0.0 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2760 PF10816.3 EWM23634.1 - 0.049 13.1 0.0 0.11 11.9 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2760) CGI-121 PF08617.5 EWM23636.1 - 7.8e-22 77.6 0.0 1e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 Kinase binding protein CGI-121 HLH PF00010.21 EWM23637.1 - 5.1e-07 29.2 3.1 1e-06 28.3 2.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.1 EWM23637.1 - 0.00026 21.3 0.0 0.00045 20.5 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.6 EWM23637.1 - 0.0018 18.3 0.0 0.0037 17.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.1 EWM23637.1 - 0.0067 16.2 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_11 PF14598.1 EWM23637.1 - 0.033 14.1 0.0 0.079 12.9 0.0 1.6 2 0 0 2 2 2 0 PAS domain 2-oxoacid_dh PF00198.18 EWM23638.1 - 4.7e-75 251.8 0.2 6.7e-75 251.3 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EWM23638.1 - 1.7e-20 72.3 1.9 3.1e-20 71.5 1.3 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.1 EWM23638.1 - 0.072 13.4 2.5 3.7 7.9 0.1 2.4 1 1 1 2 2 2 0 HlyD family secretion protein HlyD PF00529.15 EWM23638.1 - 0.073 12.3 2.8 0.26 10.5 0.1 2.2 1 1 1 2 2 2 0 HlyD family secretion protein DUF2360 PF10152.4 EWM23638.1 - 0.079 13.2 6.5 0.14 12.3 4.5 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) GCV_H PF01597.14 EWM23638.1 - 0.14 11.8 0.2 0.26 10.9 0.2 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein HlyD_2 PF12700.2 EWM23638.1 - 0.15 11.1 0.4 20 4.1 0.0 2.7 2 1 1 3 3 3 0 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 EWM23638.1 - 1.5 8.5 5.0 9.2 6.0 0.5 2.5 1 1 1 2 2 2 0 Biotin-lipoyl like TRM PF02005.11 EWM23640.1 - 4.2e-115 384.6 0.0 5.2e-115 384.3 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_31 PF13847.1 EWM23640.1 - 0.0024 17.4 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EWM23640.1 - 0.0063 15.6 0.1 0.016 14.3 0.0 1.6 1 1 1 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.11 EWM23640.1 - 0.0088 15.6 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein EamA PF00892.15 EWM23641.1 - 0.0012 18.8 11.0 0.0012 18.8 7.6 3.7 3 1 1 4 4 4 1 EamA-like transporter family DUF914 PF06027.7 EWM23641.1 - 0.0013 17.6 9.3 0.0013 17.6 6.4 2.0 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 EWM23641.1 - 0.0019 17.1 8.9 0.02 13.8 6.0 2.1 1 1 1 2 2 2 1 UAA transporter family DUF872 PF05915.7 EWM23641.1 - 0.056 13.2 6.1 0.69 9.7 0.1 3.4 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF872) CRT-like PF08627.5 EWM23641.1 - 0.18 11.7 3.3 0.38 10.6 2.3 1.5 1 0 0 1 1 1 0 CRT-like DUF4239 PF14023.1 EWM23641.1 - 0.57 9.5 4.1 26 4.0 2.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) ETF PF01012.16 EWM23642.1 - 2.2e-39 134.7 3.2 3.4e-39 134.2 2.2 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain GrpE PF01025.14 EWM23643.1 - 1.7e-29 102.5 4.4 2.8e-29 101.7 3.1 1.4 1 1 0 1 1 1 1 GrpE APG6 PF04111.7 EWM23643.1 - 0.023 13.7 1.5 0.03 13.3 1.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Calmodulin_bind PF07887.6 EWM23643.1 - 0.066 12.2 0.1 0.087 11.8 0.1 1.1 1 0 0 1 1 1 0 Calmodulin binding protein-like Enkurin PF13864.1 EWM23643.1 - 0.16 12.1 4.0 0.69 10.1 2.8 2.0 1 1 0 1 1 1 0 Calmodulin-binding CCDC-167 PF15188.1 EWM23643.1 - 0.17 11.8 1.3 0.34 10.8 0.9 1.6 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Prefoldin_2 PF01920.15 EWM23643.1 - 0.24 11.2 3.4 0.22 11.2 0.5 2.3 2 1 1 3 3 3 0 Prefoldin subunit PseudoU_synth_1 PF01416.15 EWM23644.1 - 1.9e-22 79.6 0.0 7.5e-10 39.1 0.0 2.9 3 0 0 3 3 3 2 tRNA pseudouridine synthase DNA_pol3_theta PF06440.6 EWM23644.1 - 0.0071 15.9 0.8 0.015 14.8 0.6 1.5 1 0 0 1 1 1 1 DNA polymerase III, theta subunit adh_short PF00106.20 EWM23645.1 - 1.2e-30 106.6 1.8 1.8e-30 106.0 1.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EWM23645.1 - 2.2e-12 46.9 0.7 3.1e-12 46.5 0.5 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EWM23645.1 - 8.5e-11 42.0 0.0 1.1e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EWM23645.1 - 0.00087 19.3 1.7 0.02 14.9 1.2 2.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EWM23645.1 - 0.0047 16.3 0.1 0.013 14.9 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EWM23645.1 - 0.034 13.0 0.0 0.062 12.1 0.0 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Maf_N PF08383.6 EWM23645.1 - 0.067 12.7 2.5 0.17 11.4 0.0 2.8 3 1 1 4 4 4 0 Maf N-terminal region Choline_transpo PF04515.7 EWM23647.1 - 1.9e-43 148.5 17.9 3.2e-24 85.3 2.8 3.1 2 1 2 4 4 4 2 Plasma-membrane choline transporter tRNA_U5-meth_tr PF05958.6 EWM23648.1 - 7.2e-59 199.2 0.0 3.2e-14 52.3 0.0 6.0 6 0 0 6 6 6 6 tRNA (Uracil-5-)-methyltransferase Methyltransf_26 PF13659.1 EWM23648.1 - 2.4e-09 37.2 0.0 1e-08 35.2 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM23648.1 - 1.6e-05 24.5 0.0 2.9e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EWM23648.1 - 2.5e-05 23.9 0.0 4.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.2 EWM23648.1 - 3.1e-05 24.4 0.1 0.00017 22.1 0.0 2.1 1 1 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EWM23648.1 - 5.9e-05 22.5 0.0 0.00039 19.8 0.0 2.2 3 0 0 3 3 3 1 Conserved hypothetical protein 95 RrnaAD PF00398.15 EWM23648.1 - 0.00016 20.7 0.0 0.00026 20.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.1 EWM23648.1 - 0.00085 19.6 0.0 0.0019 18.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM23648.1 - 0.0012 19.2 0.0 0.0031 17.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EWM23648.1 - 0.0046 16.0 0.0 0.0073 15.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EWM23648.1 - 0.0074 15.6 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EWM23648.1 - 0.036 13.5 0.0 0.083 12.4 0.0 1.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 EWM23648.1 - 0.039 13.0 0.0 0.062 12.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.11 EWM23648.1 - 0.055 13.0 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_12 PF08242.7 EWM23648.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AAR2 PF05282.6 EWM23650.1 - 2.6e-50 171.3 0.0 3e-24 85.6 0.0 2.1 2 0 0 2 2 2 2 AAR2 protein Ribosomal_S21 PF01165.15 EWM23651.1 - 5.1e-18 64.2 3.7 7.2e-18 63.7 2.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S21 FliJ PF02050.11 EWM23651.1 - 0.16 12.0 3.9 0.21 11.6 2.7 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein SAE2 PF08573.5 EWM23652.1 - 1.8e-09 38.1 7.9 4.6e-08 33.6 0.3 3.5 2 1 1 3 3 3 2 DNA repair protein endonuclease SAE2/CtIP C-terminus TMEM192 PF14802.1 EWM23652.1 - 2.6 6.8 4.2 3.9 6.2 2.9 1.2 1 0 0 1 1 1 0 TMEM192 family DUF4200 PF13863.1 EWM23652.1 - 7 6.6 19.8 0.16 11.8 9.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) TPR_11 PF13414.1 EWM23653.1 - 5.6e-18 64.3 10.5 2.3e-09 36.7 0.4 3.2 1 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 EWM23653.1 - 1.1e-17 62.8 5.8 4.3e-08 32.4 0.1 4.3 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 EWM23653.1 - 4.7e-16 57.3 4.2 8.2e-06 25.3 0.1 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 EWM23653.1 - 4.7e-12 45.6 5.9 2.3e-07 30.6 0.2 3.1 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EWM23653.1 - 2.8e-10 40.5 8.3 1.9e-07 31.5 0.9 3.3 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 EWM23653.1 - 4e-09 36.2 3.0 8.3e-06 25.5 0.0 3.1 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EWM23653.1 - 4.6e-09 35.4 3.5 0.022 14.4 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EWM23653.1 - 8.2e-09 35.3 7.8 0.024 15.2 0.1 5.1 1 1 4 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 EWM23653.1 - 7.1e-06 26.1 4.7 1.5 9.4 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EWM23653.1 - 1.9e-05 24.9 1.4 0.0042 17.3 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EWM23653.1 - 3.3e-05 23.7 8.6 0.008 16.3 0.0 4.1 5 0 0 5 5 3 1 Tetratricopeptide repeat MIT PF04212.13 EWM23653.1 - 0.00025 20.8 1.5 0.083 12.7 0.0 3.5 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_7 PF13176.1 EWM23653.1 - 0.00037 20.0 0.3 0.84 9.5 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 EWM23653.1 - 0.0044 16.1 1.8 1.4 7.8 0.0 3.1 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.9 EWM23653.1 - 0.061 13.7 5.5 29 5.4 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.4 EWM23653.1 - 6.3 6.7 7.4 6.3 6.7 0.3 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat PAS_8 PF13188.1 EWM23655.1 - 1.9e-05 24.3 0.0 4.4e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 EWM23655.1 - 0.00075 19.2 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 EWM23655.1 - 0.04 13.9 0.0 0.089 12.8 0.0 1.6 1 0 0 1 1 1 0 PAS fold PA PF02225.17 EWM23657.1 - 8.8e-16 57.4 0.0 1.7e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-RING_2 PF13639.1 EWM23657.1 - 3.6e-13 49.0 4.8 3.6e-13 49.0 3.3 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EWM23657.1 - 1.9e-09 37.0 3.2 1.9e-09 37.0 2.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EWM23657.1 - 2.2e-07 30.8 5.4 6.8e-07 29.3 3.7 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EWM23657.1 - 4.4e-07 29.8 3.9 4.4e-07 29.8 2.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EWM23657.1 - 6.8e-07 28.9 2.2 6.8e-07 28.9 1.5 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EWM23657.1 - 4.3e-05 23.0 4.5 4.3e-05 23.0 3.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EWM23657.1 - 0.00074 19.3 2.3 0.00074 19.3 1.6 1.8 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EWM23657.1 - 0.021 14.8 3.4 0.03 14.3 1.7 1.8 1 1 0 1 1 1 0 RING-variant domain PHD PF00628.24 EWM23657.1 - 0.051 13.2 2.8 0.11 12.1 2.0 1.6 1 0 0 1 1 1 0 PHD-finger DUF3481 PF11980.3 EWM23657.1 - 0.17 11.7 0.1 0.17 11.7 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3481) zf-RING-like PF08746.6 EWM23657.1 - 0.57 10.2 5.2 0.35 10.9 0.4 2.4 2 0 0 2 2 2 0 RING-like domain DUF92 PF01940.11 EWM23658.1 - 7.3e-60 201.9 4.9 9.5e-60 201.5 3.4 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 CBFD_NFYB_HMF PF00808.18 EWM23659.1 - 3.8e-09 36.4 0.0 8.9e-09 35.2 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EWM23659.1 - 0.0029 17.3 0.0 0.0044 16.7 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TAF PF02969.12 EWM23659.1 - 0.012 15.5 0.0 0.024 14.5 0.0 1.5 1 1 0 1 1 1 0 TATA box binding protein associated factor (TAF) CTNNB1_binding PF08347.6 EWM23659.1 - 0.067 13.4 0.7 0.092 12.9 0.5 1.1 1 0 0 1 1 1 0 N-terminal CTNNB1 binding Histone PF00125.19 EWM23659.1 - 0.076 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Metallophos PF00149.23 EWM23660.1 - 4.3e-35 120.9 0.0 6.5e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 EWM23660.1 - 5.2e-23 80.4 9.3 1.8e-15 56.3 2.2 2.6 1 1 1 2 2 2 2 TPR repeat PPP5 PF08321.7 EWM23660.1 - 2.4e-18 65.9 0.0 1e-17 63.8 0.0 2.1 1 1 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.23 EWM23660.1 - 1.9e-16 58.8 4.3 1.4e-05 24.5 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EWM23660.1 - 2.9e-16 58.0 5.7 0.00019 21.1 0.1 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EWM23660.1 - 1.1e-09 38.6 6.1 6.8e-05 23.4 0.9 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 EWM23660.1 - 2.4e-07 30.5 1.2 0.003 17.3 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EWM23660.1 - 2.9e-06 26.6 1.4 0.077 12.8 0.0 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EWM23660.1 - 1.4e-05 25.3 1.6 1.1 10.1 0.0 3.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EWM23660.1 - 7.6e-05 22.5 7.5 0.011 15.6 0.6 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 EWM23660.1 - 8.1e-05 22.8 1.8 0.05 14.0 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EWM23660.1 - 0.00026 21.2 2.2 0.016 15.4 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EWM23660.1 - 0.001 19.0 2.5 0.024 14.8 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.12 EWM23660.1 - 0.0014 18.9 0.6 0.0036 17.6 0.4 1.6 1 0 0 1 1 1 1 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.1 EWM23660.1 - 0.0072 16.1 0.8 0.21 11.5 0.0 2.9 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.1 EWM23660.1 - 0.02 14.6 1.1 0.72 9.8 0.1 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EWM23660.1 - 0.024 14.7 2.4 0.054 13.6 1.7 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 EWM23660.1 - 0.031 14.1 3.1 1.9 8.4 0.5 2.5 1 1 1 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_20 PF14561.1 EWM23660.1 - 0.093 12.8 0.1 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat YfiO PF13525.1 EWM23660.1 - 0.12 11.8 2.8 0.91 8.9 1.8 2.0 1 1 1 2 2 2 0 Outer membrane lipoprotein DUF3856 PF12968.2 EWM23660.1 - 0.28 10.9 2.1 23 4.7 0.8 3.4 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) Choline_transpo PF04515.7 EWM23662.1 - 3.8e-81 272.4 28.2 3.8e-81 272.4 19.6 1.6 2 0 0 2 2 2 1 Plasma-membrane choline transporter DUF3754 PF12576.3 EWM23662.1 - 6.1 6.4 5.9 0.83 9.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) Nucleoporin_C PF03177.9 EWM23663.1 - 0.17 10.3 14.2 1.2 7.5 6.2 3.1 2 1 0 2 2 2 0 Non-repetitive/WGA-negative nucleoporin C-terminal PUB PF09409.5 EWM23664.1 - 9.8e-15 54.0 0.0 1.7e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 PUB domain PDZ PF00595.19 EWM23664.1 - 2.6e-06 27.5 0.2 7.7e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EWM23664.1 - 4.1e-06 26.5 0.0 8.6e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.1 EWM23664.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Tricorn protease PDZ domain DER1 PF04511.10 EWM23665.1 - 1.8e-44 151.6 2.6 2.7e-44 151.0 1.5 1.5 2 0 0 2 2 2 1 Der1-like family DnaJ PF00226.26 EWM23666.1 - 8.1e-22 76.7 0.6 8.1e-22 76.7 0.4 1.7 2 0 0 2 2 2 1 DnaJ domain His_Phos_2 PF00328.17 EWM23668.1 - 2.3e-27 96.2 0.0 2.4e-15 56.7 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Pkinase PF00069.20 EWM23669.1 - 2e-48 164.8 0.0 5.2e-44 150.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EWM23669.1 - 4.8e-30 104.4 0.0 8.9e-28 97.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EWM23669.1 - 0.0072 15.3 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like hNIFK_binding PF12196.3 EWM23669.1 - 0.036 13.4 0.1 0.16 11.4 0.0 2.1 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK Citrate_synt PF00285.16 EWM23670.1 - 2.1e-111 372.0 0.0 2.5e-111 371.8 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase Met_10 PF02475.11 EWM23671.1 - 1.5e-56 191.1 0.0 4.8e-56 189.5 0.0 1.8 1 1 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 EWM23671.1 - 0.047 14.2 0.0 0.1 13.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RNA_pol_Rpb1_5 PF04998.12 EWM23672.1 - 2.7e-94 315.5 0.0 4.4e-94 314.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EWM23672.1 - 6.9e-86 288.5 0.0 9.3e-86 288.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EWM23672.1 - 6.7e-67 224.5 0.0 1.4e-66 223.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EWM23672.1 - 3.2e-37 127.6 0.0 6e-37 126.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EWM23672.1 - 2.7e-26 91.4 0.0 6.9e-26 90.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 FA_hydroxylase PF04116.8 EWM23673.1 - 6e-17 62.0 12.5 6e-17 62.0 8.7 1.9 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily HemY_N PF07219.8 EWM23674.1 - 0.43 10.1 2.3 0.91 9.1 0.0 2.0 2 0 0 2 2 2 0 HemY protein N-terminus eRF1_1 PF03463.10 EWM23676.1 - 1.1e-45 154.4 0.0 1.6e-45 153.8 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 EWM23676.1 - 7.5e-29 100.7 0.0 1.1e-28 100.1 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EWM23676.1 - 3.9e-19 68.9 0.0 8.4e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 6PF2K PF01591.13 EWM23677.1 - 2.7e-69 232.6 0.1 3.8e-69 232.1 0.1 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EWM23677.1 - 2.9e-16 59.9 0.2 1.8e-15 57.3 0.0 2.4 2 2 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EWM23677.1 - 1.6e-08 34.4 0.0 3.4e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EWM23677.1 - 0.0023 18.7 0.0 0.0067 17.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EWM23677.1 - 0.0029 16.8 0.0 0.0064 15.7 0.0 1.6 1 0 0 1 1 1 1 Chromatin associated protein KTI12 bZIP_1 PF00170.16 EWM23679.1 - 5.9e-10 38.9 17.2 5.9e-10 38.9 11.9 2.7 2 1 1 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.10 EWM23679.1 - 2.6e-07 30.3 15.1 2.6e-07 30.3 10.5 2.2 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 EWM23679.1 - 0.00043 20.5 9.5 0.00043 20.5 6.6 3.1 3 0 0 3 3 3 1 bZIP Maf transcription factor DUF3128 PF11326.3 EWM23679.1 - 1.1 9.4 8.4 60 3.8 5.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3128) TSC22 PF01166.13 EWM23679.1 - 1.3 8.9 7.4 1.5 8.8 1.9 3.0 2 1 0 2 2 2 0 TSC-22/dip/bun family H_PPase PF03030.11 EWM23680.1 - 3.5e-260 865.0 32.0 4.3e-260 864.7 22.2 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase PsbL PF02419.12 EWM23680.1 - 3.4 7.1 5.5 1.2 8.6 0.6 2.6 2 0 0 2 2 2 0 PsbL protein PTR2 PF00854.16 EWM23683.1 - 1.3e-62 211.7 2.2 1.3e-62 211.7 1.5 2.5 2 1 0 2 2 2 1 POT family AmoC PF04896.7 EWM23683.1 - 0.5 9.3 6.3 0.33 9.9 1.9 2.1 2 0 0 2 2 2 0 Ammonia monooxygenase/methane monooxygenase, subunit C Sulfate_transp PF00916.15 EWM23684.1 - 1.6e-59 201.1 3.5 2.8e-59 200.4 2.4 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EWM23684.1 - 1.5e-28 98.2 1.1 1.5e-28 98.2 0.8 3.4 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif Mad3_BUB1_I PF08311.7 EWM23685.1 - 2.1e-05 24.3 0.2 4.2e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 TPR_14 PF13428.1 EWM23685.1 - 6e-05 23.3 5.8 0.087 13.5 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EWM23685.1 - 0.00017 22.1 0.4 0.0098 16.5 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EWM23685.1 - 0.00034 20.4 0.1 0.0013 18.6 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EWM23685.1 - 0.0018 18.0 0.7 0.92 9.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EWM23685.1 - 0.0037 16.9 2.9 2 8.3 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EWM23685.1 - 0.029 14.0 0.3 1.2 8.7 0.0 2.6 2 1 0 2 2 2 0 TPR repeat CMAS PF02353.15 EWM23685.1 - 0.045 12.8 0.5 6.1 5.8 0.0 2.3 1 1 1 2 2 2 0 Mycolic acid cyclopropane synthetase RabGAP-TBC PF00566.13 EWM23686.1 - 2.1e-40 138.5 0.0 4.6e-40 137.3 0.0 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain BAR PF03114.13 EWM23686.1 - 0.0011 18.5 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 BAR domain Exo_endo_phos PF03372.18 EWM23687.1 - 3.5e-09 36.9 0.0 5e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Bax1-I PF01027.15 EWM23688.1 - 6e-43 146.8 30.5 7.2e-43 146.5 21.2 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 CcmD PF04995.9 EWM23688.1 - 0.1 12.3 0.0 0.1 12.3 0.0 2.7 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) Transport_MerF PF11431.3 EWM23688.1 - 0.2 11.3 3.4 0.78 9.4 0.0 3.0 2 0 0 2 2 2 0 Membrane transport protein MerF AAA PF00004.24 EWM23689.1 - 4.8e-70 233.8 0.0 1.7e-43 148.0 0.0 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EWM23689.1 - 3.6e-05 23.8 4.8 0.16 11.9 0.0 3.8 3 1 1 4 4 4 2 AAA ATPase domain AAA_2 PF07724.9 EWM23689.1 - 5.1e-05 23.2 0.0 0.005 16.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EWM23689.1 - 8e-05 21.7 0.0 0.00025 20.1 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EWM23689.1 - 0.00017 21.3 0.2 0.0096 15.6 0.1 3.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EWM23689.1 - 0.00022 21.3 0.0 2.3 8.3 0.0 3.5 3 1 1 4 4 4 2 AAA domain AAA_25 PF13481.1 EWM23689.1 - 0.00024 20.5 0.5 0.38 10.1 0.0 3.1 2 1 0 3 3 3 2 AAA domain TIP49 PF06068.8 EWM23689.1 - 0.044 12.5 0.0 0.068 11.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_14 PF13173.1 EWM23689.1 - 0.072 12.9 0.0 0.35 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 EWM23689.1 - 0.076 11.6 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Sigma54_activ_2 PF14532.1 EWM23689.1 - 0.081 12.9 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 EWM23689.1 - 0.088 11.9 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EWM23689.1 - 0.096 12.0 0.0 0.24 10.7 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein KaiC PF06745.8 EWM23689.1 - 0.13 11.3 0.0 1.3 8.0 0.0 2.1 2 0 0 2 2 2 0 KaiC PEX11 PF05648.9 EWM23691.1 - 3.6e-32 111.4 0.8 2.7e-31 108.5 0.5 1.9 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) AAA PF00004.24 EWM23692.1 - 1.3e-34 119.2 0.0 2.6e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EWM23692.1 - 2e-08 33.5 0.0 4.3e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EWM23692.1 - 2.5e-05 24.4 0.1 0.0044 17.1 0.0 2.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EWM23692.1 - 7.1e-05 22.5 0.1 0.00046 19.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ResIII PF04851.10 EWM23692.1 - 9.4e-05 22.3 0.0 0.00021 21.1 0.0 1.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_16 PF13191.1 EWM23692.1 - 0.00022 21.2 0.1 0.00057 19.9 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EWM23692.1 - 0.0013 19.5 0.0 0.0028 18.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EWM23692.1 - 0.002 17.9 0.0 0.0051 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EWM23692.1 - 0.0023 17.8 0.0 0.0051 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EWM23692.1 - 0.0024 17.5 1.2 0.0092 15.7 0.0 2.6 3 0 0 3 3 3 1 Part of AAA domain Sigma54_activ_2 PF14532.1 EWM23692.1 - 0.02 14.9 0.1 0.48 10.4 0.0 3.0 4 0 0 4 4 4 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 EWM23692.1 - 0.025 13.6 0.1 0.062 12.3 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.1 EWM23692.1 - 0.032 14.5 0.0 0.064 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EWM23692.1 - 0.046 13.6 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EWM23692.1 - 0.065 12.7 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EWM23692.1 - 0.073 12.5 0.0 0.76 9.2 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.1 EWM23692.1 - 0.091 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EWM23692.1 - 0.17 10.9 0.1 3.1 6.8 0.0 2.1 1 1 0 1 1 1 0 KaiC Hairy_orange PF07527.8 EWM23694.1 - 0.002 17.8 0.4 0.0049 16.5 0.3 1.6 1 0 0 1 1 1 1 Hairy Orange ADIP PF11559.3 EWM23694.1 - 0.74 9.7 5.4 1.6 8.5 3.8 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding FBPase PF00316.15 EWM23695.1 - 4.7e-94 314.8 0.0 5.5e-94 314.6 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 EWM23695.1 - 2e-05 24.0 0.0 9.6e-05 21.8 0.0 1.9 2 0 0 2 2 2 1 Inositol monophosphatase family IQ PF00612.22 EWM23696.1 - 0.063 12.9 0.2 0.16 11.7 0.1 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif Prismane PF03063.15 EWM23696.1 - 0.14 10.5 5.9 6.3 5.0 4.6 2.3 2 1 0 2 2 2 0 Prismane/CO dehydrogenase family Peptidase_M15_3 PF08291.6 EWM23696.1 - 0.23 11.3 2.1 1.2 8.9 0.1 2.8 2 1 0 2 2 2 0 Peptidase M15 DUF4339 PF14237.1 EWM23697.1 - 1.3e-17 63.0 0.2 6.8e-10 38.3 0.2 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4339) RRM_6 PF14259.1 EWM23697.1 - 1.1e-12 47.7 0.0 4.6e-08 32.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EWM23697.1 - 3.5e-11 42.5 0.0 7.9e-06 25.4 0.0 3.9 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM23697.1 - 2.3e-06 27.3 0.0 0.00024 20.8 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GYF PF02213.11 EWM23697.1 - 2.5e-06 26.9 0.3 0.084 12.4 0.0 2.8 2 0 0 2 2 2 2 GYF domain CW_binding_1 PF01473.15 EWM23697.1 - 0.61 10.3 4.3 0.45 10.7 0.2 2.8 3 0 0 3 3 3 0 Putative cell wall binding repeat Gcd10p PF04189.8 EWM23698.1 - 2.1e-54 184.7 0.0 3.9e-54 183.8 0.0 1.3 1 0 0 1 1 1 1 Gcd10p family DAGAT PF03982.8 EWM23699.1 - 3.1e-29 101.6 0.0 4.6e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase tRNA-synt_1e PF01406.14 EWM23700.1 - 5.6e-106 354.0 0.0 7.9e-106 353.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EWM23700.1 - 1.5e-17 63.3 0.1 1.9e-08 33.4 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EWM23700.1 - 0.00038 18.6 0.0 0.05 11.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) JmjN PF02375.12 EWM23700.1 - 0.16 11.5 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 jmjN domain MMR_HSR1 PF01926.18 EWM23702.1 - 4.3e-18 65.3 0.0 1e-17 64.1 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EWM23702.1 - 1.7e-10 40.4 0.0 2.2e-09 36.8 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EWM23702.1 - 0.00043 20.1 0.4 0.08 12.7 0.0 2.3 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 EWM23702.1 - 0.002 16.9 0.3 0.0062 15.3 0.1 1.8 2 0 0 2 2 2 1 ArgK protein Miro PF08477.8 EWM23702.1 - 0.0053 17.2 0.0 0.017 15.6 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 EWM23702.1 - 0.0054 16.1 1.7 2.3 7.6 0.0 3.9 2 2 1 3 3 3 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 EWM23702.1 - 0.066 12.3 0.0 0.089 11.8 0.0 1.2 1 0 0 1 1 1 0 AIG1 family Prismane PF03063.15 EWM23704.1 - 6.3e-147 490.0 0.0 9.5e-147 489.4 0.0 1.3 1 1 0 1 1 1 1 Prismane/CO dehydrogenase family DSPc PF00782.15 EWM23705.1 - 9.8e-10 38.1 0.0 1.8e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EWM23705.1 - 0.008 16.4 0.0 0.018 15.2 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EWM23705.1 - 0.018 14.3 0.0 0.03 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase AAA_16 PF13191.1 EWM23706.1 - 0.0021 18.1 0.0 0.0042 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EWM23706.1 - 0.0099 15.3 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.1 EWM23706.1 - 0.061 13.0 0.1 0.15 11.7 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 EWM23706.1 - 0.063 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EWM23706.1 - 0.097 12.9 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 EWM23706.1 - 0.1 12.3 0.4 0.22 11.2 0.3 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EWM23706.1 - 0.13 12.1 0.1 0.24 11.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EWM23706.1 - 0.19 11.9 0.5 0.34 11.1 0.3 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NUC153 PF08159.7 EWM23707.1 - 1e-09 37.8 1.4 2e-09 36.8 1.0 1.4 1 0 0 1 1 1 1 NUC153 domain Kinesin PF00225.18 EWM23708.1 - 2.5e-95 319.0 0.0 5.7e-95 317.8 0.0 1.7 1 0 0 1 1 1 1 Kinesin motor domain Chloroa_b-bind PF00504.16 EWM23709.1 - 9.2e-09 35.7 1.5 1.8e-08 34.7 0.8 1.6 1 1 0 1 1 1 1 Chlorophyll A-B binding protein CopD PF05425.8 EWM23709.1 - 0.27 11.4 11.6 0.9 9.7 0.0 3.5 3 1 1 4 4 4 0 Copper resistance protein D VPS28 PF03997.7 EWM23710.1 - 1.8e-55 187.4 0.1 2.2e-55 187.2 0.1 1.1 1 0 0 1 1 1 1 VPS28 protein SHOCT PF09851.4 EWM23710.1 - 0.054 12.9 0.0 11 5.6 0.0 2.7 2 0 0 2 2 2 0 Short C-terminal domain HTH_32 PF13565.1 EWM23711.1 - 0.048 14.4 0.0 0.14 12.9 0.0 1.8 1 1 0 1 1 1 0 Homeodomain-like domain ClpS PF02617.12 EWM23711.1 - 0.11 12.2 0.1 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 ATP-dependent Clp protease adaptor protein ClpS DUF791 PF05631.9 EWM23712.1 - 5.4e-26 91.1 2.1 7.4e-26 90.6 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 EWM23712.1 - 3.6e-06 25.9 17.8 3.6e-06 25.9 12.3 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF791 PF05631.9 EWM23713.1 - 1.9e-09 36.7 0.0 2.2e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF791) Acylphosphatase PF00708.13 EWM23714.1 - 7.3e-15 54.8 0.0 9.1e-15 54.5 0.0 1.1 1 0 0 1 1 1 1 Acylphosphatase DUF2871 PF11070.3 EWM23714.1 - 0.099 12.8 0.1 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2871) AAA_33 PF13671.1 EWM23717.1 - 0.00028 20.7 0.0 0.053 13.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain SR-25 PF10500.4 EWM23717.1 - 0.004 16.6 11.0 0.0061 16.0 7.6 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein AAA_28 PF13521.1 EWM23717.1 - 0.027 14.4 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EWM23717.1 - 0.13 13.1 0.0 0.21 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 EWM23717.1 - 0.18 11.0 0.0 0.47 9.6 0.0 1.6 2 0 0 2 2 2 0 ADP-ribosylation factor family CAF-1_p150 PF11600.3 EWM23717.1 - 6 6.1 5.7 8.8 5.6 4.0 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal NCD3G PF07562.9 EWM23718.1 - 5.8 6.7 9.0 5.9 6.6 4.0 2.5 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR PAS_4 PF08448.5 EWM23721.1 - 1.5e-09 37.8 0.0 2.7e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 EWM23721.1 - 1.9e-05 24.3 0.0 4.2e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 EWM23721.1 - 0.00082 19.7 0.0 0.0015 18.8 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_11 PF14598.1 EWM23721.1 - 0.049 13.5 0.0 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 PAS domain PAS_8 PF13188.1 EWM23721.1 - 0.098 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 PAS domain PAS_3 PF08447.6 EWM23721.1 - 0.12 12.4 0.0 1.2 9.2 0.0 2.1 2 0 0 2 2 2 0 PAS fold GAS PF13851.1 EWM23722.1 - 0.019 14.1 1.1 0.025 13.7 0.7 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.3 EWM23722.1 - 0.039 13.7 4.8 0.056 13.2 3.3 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.3 EWM23722.1 - 0.52 10.2 4.3 0.79 9.6 3.0 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Cep57_CLD_2 PF14197.1 EWM23722.1 - 1.9 8.4 7.0 0.34 10.8 1.0 2.1 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Atg14 PF10186.4 EWM23722.1 - 1.9 7.3 3.6 2.8 6.8 2.5 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 EAF PF09816.4 EWM23724.1 - 1.7e-05 24.7 0.0 2.2e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor DUF3961 PF13106.1 EWM23725.1 - 0.072 12.6 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) Lactamase_B_3 PF13483.1 EWM23726.1 - 3.7e-12 46.2 0.0 8.4e-12 45.1 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF1754 PF08555.5 EWM23731.1 - 0.004 17.7 2.6 0.004 17.7 1.8 2.1 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) Cyto_heme_lyase PF01265.12 EWM23732.1 - 1.3e-65 221.6 0.1 1.4e-65 221.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Patched PF02460.13 EWM23733.1 - 4.9e-49 167.0 0.0 4.5e-31 107.5 0.0 2.3 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.3 EWM23733.1 - 3.9e-38 130.3 15.8 7.8e-22 77.3 0.4 3.7 4 1 1 5 5 5 2 Sterol-sensing domain of SREBP cleavage-activation DUF3693 PF12472.3 EWM23733.1 - 0.36 10.4 0.0 0.36 10.4 0.0 2.8 4 0 0 4 4 4 0 Phage related protein Zn_clus PF00172.13 EWM23734.1 - 1e-06 28.5 6.5 1.6e-06 27.8 4.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RhoGEF PF00621.15 EWM23739.1 - 1.4e-10 41.3 0.0 1.1e-09 38.4 0.0 2.1 1 1 0 1 1 1 1 RhoGEF domain PH PF00169.24 EWM23739.1 - 0.072 13.2 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 PH domain Ribosomal_L30_N PF08079.7 EWM23743.1 - 3e-09 36.7 12.0 4.7e-09 36.1 8.3 1.3 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain YebO PF13974.1 EWM23743.1 - 0.14 11.9 0.2 0.21 11.4 0.1 1.2 1 0 0 1 1 1 0 YebO-like protein API5 PF05918.6 EWM23743.1 - 0.19 10.1 1.9 0.21 10.0 1.3 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) TPR_11 PF13414.1 EWM23747.1 - 3.6e-21 74.5 2.5 1.8e-19 69.1 0.6 1.7 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EWM23747.1 - 2e-09 36.6 2.9 1.5e-06 27.6 0.3 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EWM23747.1 - 5.2e-08 32.1 2.4 2.1e-06 27.0 0.2 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EWM23747.1 - 9.5e-06 26.1 0.2 1.8e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 EWM23747.1 - 3.9e-05 23.4 0.2 0.29 11.4 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EWM23747.1 - 0.00097 19.0 0.7 0.031 14.2 0.4 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EWM23747.1 - 0.0022 18.2 0.1 0.0051 17.1 0.1 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.1 EWM23747.1 - 0.0025 17.6 0.1 0.32 10.8 0.0 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EWM23747.1 - 0.0034 17.0 0.7 0.01 15.5 0.0 2.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EWM23747.1 - 0.0095 16.4 0.1 0.029 14.9 0.0 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EWM23747.1 - 0.024 14.4 0.1 3.4 7.6 0.0 2.5 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 EWM23747.1 - 0.14 12.1 1.0 0.26 11.2 0.2 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat PT PF04886.7 EWM23750.1 - 0.0013 18.0 18.8 0.0013 18.0 13.0 4.1 1 1 1 2 2 2 1 PT repeat DUF4394 PF14339.1 EWM23750.1 - 0.027 13.7 1.7 2.1 7.5 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4394) WW PF00397.21 EWM23750.1 - 3.3 7.6 7.4 16 5.5 0.1 3.2 3 0 0 3 3 3 0 WW domain PTPA PF03095.10 EWM23753.1 - 5.2e-19 68.5 0.0 5.9e-19 68.3 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Cys_Met_Meta_PP PF01053.15 EWM23757.1 - 3e-131 437.2 0.0 3.4e-131 437.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EWM23757.1 - 8.1e-08 31.6 0.0 1.8e-06 27.2 0.0 2.5 2 1 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EWM23757.1 - 2.7e-06 26.5 0.0 5e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.6 EWM23757.1 - 0.0049 15.2 0.1 0.0074 14.6 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.16 EWM23757.1 - 0.02 14.0 0.1 0.25 10.4 0.1 2.2 1 1 0 1 1 1 0 Beta-eliminating lyase ThiG PF05690.9 EWM23757.1 - 0.064 12.3 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG ABC_membrane_2 PF06472.10 EWM23759.1 - 1.7e-37 129.0 0.0 2e-37 128.8 0.0 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 TauD PF02668.11 EWM23759.1 - 0.038 13.6 0.0 0.047 13.3 0.0 1.1 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family ABC_membrane_2 PF06472.10 EWM23760.1 - 5.9e-27 94.5 0.1 8.5e-27 93.9 0.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 Hairy_orange PF07527.8 EWM23760.1 - 0.16 11.7 0.5 1.2 8.9 0.1 2.5 2 0 0 2 2 2 0 Hairy Orange Mito_fiss_reg PF05308.6 EWM23760.1 - 0.85 8.9 6.3 1.2 8.4 4.4 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 EWM23760.1 - 4.6 6.4 6.3 6.7 5.9 4.4 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Phospholip_B PF04916.8 EWM23764.1 - 5.9e-19 67.6 0.0 7.4e-19 67.2 0.0 1.1 1 0 0 1 1 1 1 Phospholipase B CytochromB561_N PF09786.4 EWM23764.1 - 0.11 10.8 0.0 0.14 10.5 0.0 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal MRFAP1 PF15155.1 EWM23765.1 - 0.029 14.7 0.3 0.033 14.5 0.2 1.2 1 0 0 1 1 1 0 MORF4 family-associated protein1 AAA_16 PF13191.1 EWM23766.1 - 5.9e-05 23.1 0.1 0.0002 21.4 0.0 1.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EWM23766.1 - 0.00017 21.7 0.0 0.0003 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EWM23766.1 - 0.00041 20.0 0.0 0.00069 19.3 0.0 1.6 1 1 0 1 1 1 1 NACHT domain AAA PF00004.24 EWM23766.1 - 0.00067 19.8 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EWM23766.1 - 0.0031 17.4 0.0 0.0045 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 EWM23766.1 - 0.0064 15.5 0.0 0.0068 15.4 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain AAA_25 PF13481.1 EWM23766.1 - 0.0067 15.8 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EWM23766.1 - 0.013 16.3 0.0 0.018 15.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 EWM23766.1 - 0.054 12.9 0.0 0.089 12.2 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Thymidylate_kin PF02223.12 EWM23766.1 - 0.06 12.7 0.0 0.092 12.1 0.0 1.2 1 0 0 1 1 1 0 Thymidylate kinase AAA_24 PF13479.1 EWM23766.1 - 0.083 12.4 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EWM23766.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.17 EWM23766.1 - 0.11 12.6 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 EWM23766.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EWM23766.1 - 0.16 11.6 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase RuvB_N PF05496.7 EWM23766.1 - 0.17 10.8 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus BNR PF02012.15 EWM23769.1 - 0.18 11.7 0.7 1.3 9.1 1.0 2.2 2 0 0 2 2 2 0 BNR/Asp-box repeat BNR_3 PF13859.1 EWM23769.1 - 0.35 9.8 1.8 0.32 10.0 0.5 1.5 1 1 1 2 2 2 0 BNR repeat-like domain DUF1180 PF06679.7 EWM23769.1 - 3.5 7.4 6.1 2 8.2 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Zip PF02535.17 EWM23774.1 - 4.1e-05 22.7 0.8 4.3e-05 22.6 0.5 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF456 PF04306.8 EWM23774.1 - 0.0015 18.5 1.2 0.0016 18.5 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF456) DUF4203 PF13886.1 EWM23774.1 - 0.026 14.0 0.9 0.027 13.9 0.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) DctQ PF04290.7 EWM23774.1 - 0.032 13.9 0.7 0.035 13.8 0.5 1.1 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component MVIN PF03023.9 EWM23774.1 - 0.054 11.9 0.1 0.063 11.6 0.1 1.1 1 0 0 1 1 1 0 MviN-like protein Gate PF07670.9 EWM23774.1 - 0.064 13.1 0.2 0.066 13.1 0.1 1.1 1 0 0 1 1 1 0 Nucleoside recognition PSII_BNR PF14870.1 EWM23775.1 - 0.0004 19.4 4.2 0.00047 19.2 2.9 1.1 1 0 0 1 1 1 1 Photosynthesis system II assembly factor YCF48 BNR_3 PF13859.1 EWM23775.1 - 0.0008 18.5 4.4 0.039 13.0 0.1 2.0 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.15 EWM23775.1 - 0.092 12.6 0.1 0.092 12.6 0.1 4.0 5 0 0 5 5 5 0 BNR/Asp-box repeat E1-E2_ATPase PF00122.15 EWM23776.1 - 1.5e-45 154.9 0.1 2.8e-45 154.1 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EWM23776.1 - 3.9e-41 141.8 0.1 1.2e-40 140.2 0.1 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EWM23776.1 - 8.1e-26 89.9 3.0 2.9e-11 43.3 0.2 4.0 4 0 0 4 4 4 3 Heavy-metal-associated domain HAD PF12710.2 EWM23776.1 - 1.4e-14 54.7 0.0 3.2e-14 53.5 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EWM23776.1 - 0.00058 19.5 0.7 0.00088 18.9 0.5 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Rhodanese PF00581.15 EWM23777.1 - 1e-21 77.4 0.0 2.5e-12 47.1 0.0 2.4 2 0 0 2 2 2 2 Rhodanese-like domain Rhodanese PF00581.15 EWM23778.1 - 7.8e-19 68.0 0.0 4.9e-09 36.5 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain RCC1 PF00415.13 EWM23779.1 - 4e-24 84.5 20.9 2.7e-10 40.2 0.2 6.9 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EWM23779.1 - 1.1e-15 56.8 19.3 0.00012 21.5 0.4 5.2 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 EWM23780.1 - 8.7e-28 96.2 20.3 2.3e-10 40.5 0.2 6.8 5 1 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EWM23780.1 - 4.6e-16 57.9 19.4 0.00011 21.7 0.4 5.3 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat SGL PF08450.7 EWM23782.1 - 1.9e-67 227.2 0.0 2.2e-67 227.0 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Lactonase PF10282.4 EWM23782.1 - 0.18 10.8 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller ThylakoidFormat PF11264.3 EWM23783.1 - 2.3e-05 24.1 0.2 2.9e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Thylakoid formation protein NUDIX PF00293.23 EWM23784.1 - 0.00062 19.4 0.0 0.00089 18.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF605 PF04652.11 EWM23786.1 - 0.15 11.4 15.4 0.15 11.4 10.7 1.1 1 0 0 1 1 1 0 Vta1 like DUF566 PF04484.7 EWM23786.1 - 0.84 9.0 21.4 1.2 8.6 14.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Trs65 PF12735.2 EWM23786.1 - 1.9 7.6 16.3 2.5 7.3 11.3 1.2 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 Presenilin PF01080.12 EWM23786.1 - 2.4 6.8 5.8 3.5 6.3 4.0 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.4 EWM23786.1 - 7.8 4.6 13.2 9.7 4.3 9.2 1.1 1 0 0 1 1 1 0 Transmembrane protein PPR PF01535.15 EWM23788.1 - 0.0057 16.5 0.6 2.7 8.1 0.0 2.7 3 1 0 3 3 3 2 PPR repeat AAA_12 PF13087.1 EWM23790.1 - 3.6e-47 160.3 0.0 1.8e-46 158.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EWM23790.1 - 4.9e-28 98.2 0.0 5.4e-27 94.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EWM23790.1 - 2.6e-11 43.5 0.0 0.0041 16.6 0.0 3.2 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EWM23790.1 - 5.5e-06 26.0 0.0 0.00011 21.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EWM23790.1 - 2.1e-05 24.6 0.0 0.019 15.1 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 EWM23790.1 - 0.00077 19.1 0.0 0.0053 16.4 0.0 2.3 1 1 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 EWM23790.1 - 0.001 19.1 0.0 0.0027 17.8 0.0 1.7 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain PhoH PF02562.11 EWM23790.1 - 0.059 12.5 0.0 0.76 8.9 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_16 PF13191.1 EWM23790.1 - 0.066 13.1 0.4 0.71 9.8 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain DUF2439 PF10382.4 EWM23792.1 - 8.4e-10 38.7 0.0 1.3e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) DUF605 PF04652.11 EWM23792.1 - 9.1 5.5 8.2 14 4.9 5.7 1.2 1 0 0 1 1 1 0 Vta1 like Glyco_hydro_9 PF00759.14 EWM23793.1 - 0.037 12.9 0.1 0.051 12.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 DUF1275 PF06912.6 EWM23794.1 - 0.00055 19.1 2.0 0.00067 18.9 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Pkinase PF00069.20 EWM23795.1 - 3.1e-05 23.2 0.0 3.7e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM23795.1 - 0.0028 16.7 0.0 0.003 16.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Abhydrolase_6 PF12697.2 EWM23796.1 - 1.6e-29 103.4 4.2 3.9e-29 102.1 2.9 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EWM23796.1 - 4.4e-20 72.2 0.0 1.2e-18 67.5 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EWM23796.1 - 2e-16 60.0 2.3 9.9e-15 54.5 1.6 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EWM23796.1 - 8.7e-09 35.1 0.0 1.6e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase DUF1057 PF06342.7 EWM23796.1 - 0.00034 19.5 0.0 0.00049 19.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Thioesterase PF00975.15 EWM23796.1 - 0.027 14.6 0.0 0.045 13.9 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.15 EWM23796.1 - 0.084 12.2 0.2 1.2 8.5 0.1 2.2 1 1 0 1 1 1 0 Putative esterase Abhydrolase_6 PF12697.2 EWM23797.1 - 1.6e-29 103.4 4.2 3.9e-29 102.1 2.9 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EWM23797.1 - 4.4e-20 72.2 0.0 1.2e-18 67.5 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EWM23797.1 - 2e-16 60.0 2.3 9.9e-15 54.5 1.6 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EWM23797.1 - 8.7e-09 35.1 0.0 1.6e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase DUF1057 PF06342.7 EWM23797.1 - 0.00034 19.5 0.0 0.00049 19.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Thioesterase PF00975.15 EWM23797.1 - 0.027 14.6 0.0 0.045 13.9 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.15 EWM23797.1 - 0.084 12.2 0.2 1.2 8.5 0.1 2.2 1 1 0 1 1 1 0 Putative esterase DUF3446 PF11928.3 EWM23798.1 - 0.17 12.0 12.3 0.23 11.6 8.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) Kinesin PF00225.18 EWM23801.1 - 1.9e-92 309.5 0.0 2.3e-92 309.3 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain DUF2763 PF10961.3 EWM23804.1 - 0.12 12.7 4.7 0.17 12.3 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) Symplekin_C PF12295.3 EWM23806.1 - 5.8e-14 52.4 0.1 6.6e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal Dynamin_N PF00350.18 EWM23811.1 - 9.6e-09 35.2 0.5 4.3e-08 33.1 0.0 2.3 2 1 1 3 3 3 1 Dynamin family Miro PF08477.8 EWM23811.1 - 0.014 15.8 0.2 0.055 13.9 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein AAA_28 PF13521.1 EWM23811.1 - 0.04 13.8 0.2 0.09 12.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EWM23811.1 - 0.072 13.0 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase UPF0079 PF02367.12 EWM23811.1 - 0.094 12.3 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 eIF-5_eIF-2B PF01873.12 EWM23811.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain found in IF2B/IF5 Response_reg PF00072.19 EWM23812.1 - 0.11 12.5 0.0 0.37 10.8 0.0 1.8 2 0 0 2 2 2 0 Response regulator receiver domain DUF1469 PF07332.6 EWM23813.1 - 0.0058 16.3 1.7 0.0096 15.6 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1469) MNHE PF01899.11 EWM23814.1 - 0.57 9.8 5.0 0.39 10.3 0.3 2.3 2 1 0 2 2 2 0 Na+/H+ ion antiporter subunit Zn_clus PF00172.13 EWM23815.1 - 4.2e-05 23.3 12.8 7.3e-05 22.5 8.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Coiled PF05710.7 EWM23817.1 - 0.19 12.2 1.1 0.19 12.1 0.7 1.0 1 0 0 1 1 1 0 Coiled coil PPR_2 PF13041.1 EWM23818.1 - 9.6e-60 198.3 0.4 2.7e-09 36.8 0.0 9.1 4 1 5 9 9 9 8 PPR repeat family PPR_3 PF13812.1 EWM23818.1 - 4.8e-50 163.6 20.5 1.3e-05 25.1 0.0 10.2 10 1 0 10 10 10 9 Pentatricopeptide repeat domain PPR PF01535.15 EWM23818.1 - 7.6e-44 144.6 11.8 1.8e-06 27.5 0.0 9.7 10 0 0 10 10 9 8 PPR repeat PPR_1 PF12854.2 EWM23818.1 - 1.8e-39 132.9 0.7 0.00014 21.2 0.0 10.7 11 0 0 11 11 11 6 PPR repeat Clathrin PF00637.15 EWM23818.1 - 0.0015 18.1 0.0 1 8.9 0.0 3.8 2 1 1 3 3 3 1 Region in Clathrin and VPS TPR_15 PF13429.1 EWM23818.1 - 0.0016 17.5 4.0 0.26 10.3 0.2 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat ECSIT PF06239.6 EWM23818.1 - 0.0074 15.1 0.3 8 5.2 0.0 4.3 3 1 0 4 4 4 1 Evolutionarily conserved signalling intermediate in Toll pathway YtzH PF14165.1 EWM23818.1 - 0.021 15.0 0.0 0.29 11.4 0.0 2.3 2 0 0 2 2 2 0 YtzH-like protein IMS_C PF11799.3 EWM23818.1 - 0.022 14.6 0.1 0.9 9.4 0.0 3.1 3 0 0 3 3 3 0 impB/mucB/samB family C-terminal domain TPR_14 PF13428.1 EWM23818.1 - 0.042 14.4 24.2 24 5.9 0.2 8.0 3 2 6 9 9 9 0 Tetratricopeptide repeat HAD_2 PF13419.1 EWM23818.1 - 0.072 13.3 0.2 0.48 10.6 0.0 2.4 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase Arg_repressor PF01316.16 EWM23818.1 - 0.076 12.5 0.0 0.45 10.1 0.0 2.3 2 0 0 2 2 2 0 Arginine repressor, DNA binding domain DoxX_2 PF13564.1 EWM23818.1 - 0.087 12.8 0.1 0.54 10.2 0.0 2.3 1 1 1 2 2 2 0 DoxX-like family Rep_fac_C PF08542.6 EWM23818.1 - 0.13 12.2 0.0 34 4.4 0.0 3.4 3 1 0 4 4 4 0 Replication factor C C-terminal domain TPR_19 PF14559.1 EWM23818.1 - 0.19 12.1 11.9 15 5.9 0.1 4.8 3 1 3 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 EWM23818.1 - 0.2 11.5 2.7 60 3.8 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 EWM23818.1 - 0.32 10.9 8.4 29 4.6 0.0 4.9 4 2 0 4 4 4 0 Tetratricopeptide repeat WD40 PF00400.27 EWM23821.1 - 1e-15 56.8 0.2 1.8e-11 43.4 0.0 2.5 2 1 0 2 2 2 2 WD domain, G-beta repeat FAD_binding_3 PF01494.14 EWM23823.1 - 3.4e-18 65.8 0.0 1.8e-05 23.9 0.0 3.2 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.19 EWM23823.1 - 1.8e-07 30.3 0.0 2.5e-07 29.9 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EWM23823.1 - 4.6e-05 23.3 0.0 0.00015 21.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ThiF PF00899.16 EWM23823.1 - 0.0011 18.7 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 ThiF family NAD_binding_9 PF13454.1 EWM23823.1 - 0.01 15.5 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EWM23823.1 - 0.026 14.5 0.0 0.047 13.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EWM23823.1 - 0.042 14.2 0.0 0.15 12.4 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EWM23823.1 - 0.044 13.6 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EWM23823.1 - 0.047 12.1 0.0 0.07 11.5 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.9 EWM23823.1 - 0.055 12.0 0.0 3.1 6.3 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.12 EWM23823.1 - 0.17 10.9 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Sigma70_r4_2 PF08281.7 EWM23824.1 - 0.011 15.1 1.4 0.041 13.3 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 PGC7_Stella PF15549.1 EWM23824.1 - 1.9 8.4 6.0 2.7 7.9 3.3 1.7 2 0 0 2 2 2 0 PGC7/Stella/Dppa3 domain ParA PF10609.4 EWM23827.1 - 3e-28 97.5 0.0 5.2e-28 96.7 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EWM23827.1 - 1.8e-15 56.8 0.0 3.9e-15 55.7 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EWM23827.1 - 1.5e-09 37.9 0.1 3.7e-09 36.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 EWM23827.1 - 1.5e-07 30.8 0.3 3.2e-07 29.7 0.1 1.6 2 0 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.10 EWM23827.1 - 6.2e-05 22.1 0.7 0.00072 18.6 0.2 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase DUF59 PF01883.14 EWM23827.1 - 0.00015 21.7 0.0 0.00041 20.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function DUF59 VirC1 PF07015.6 EWM23827.1 - 0.00073 18.6 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 VirC1 protein Fer4_NifH PF00142.13 EWM23827.1 - 0.007 15.5 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family YhjQ PF06564.7 EWM23827.1 - 0.0092 15.3 0.2 0.04 13.2 0.1 1.9 2 0 0 2 2 2 1 YhjQ protein FTHFS PF01268.14 EWM23827.1 - 0.012 13.6 0.2 0.017 13.1 0.1 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase ArgK PF03308.11 EWM23827.1 - 0.017 13.9 0.1 0.028 13.1 0.1 1.3 1 0 0 1 1 1 0 ArgK protein AAA_25 PF13481.1 EWM23827.1 - 0.039 13.3 0.0 0.11 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Yip1 PF04893.12 EWM23828.1 - 1.4e-09 37.7 14.6 1.4e-09 37.7 10.1 1.4 1 1 0 1 1 1 1 Yip1 domain YIF1 PF03878.10 EWM23828.1 - 4.1e-05 22.8 4.3 0.00069 18.8 3.0 2.1 1 1 0 1 1 1 1 YIF1 STE3 PF02076.10 EWM23829.1 - 0.022 13.8 2.0 0.43 9.6 0.1 2.1 2 0 0 2 2 2 0 Pheromone A receptor 7tm_1 PF00001.16 EWM23829.1 - 0.071 12.2 1.4 0.083 12.0 0.2 1.6 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) RL11D PF11088.3 EWM23829.1 - 0.13 12.1 0.2 0.22 11.3 0.2 1.5 1 0 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 E1-E2_ATPase PF00122.15 EWM23830.1 - 9.8e-61 204.7 7.7 9.8e-61 204.7 5.3 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EWM23830.1 - 1.3e-35 122.5 0.2 1.3e-35 122.5 0.2 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EWM23830.1 - 1.4e-32 113.8 0.0 7.5e-32 111.4 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EWM23830.1 - 1.2e-14 54.9 0.0 3e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EWM23830.1 - 8.9e-13 47.5 0.0 1.8e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EWM23830.1 - 1.2e-12 47.5 0.0 2.2e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EWM23830.1 - 9.2e-06 25.4 2.2 0.00014 21.4 0.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase TraD PF06412.6 EWM23830.1 - 0.055 13.0 0.1 0.19 11.3 0.1 1.9 1 0 0 1 1 1 0 Conjugal transfer protein TraD Mpv17_PMP22 PF04117.7 EWM23833.1 - 1.1e-13 50.5 0.1 2.2e-13 49.6 0.1 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family CDC45 PF02724.9 EWM23833.1 - 0.00091 17.3 9.5 0.0012 16.9 6.6 1.1 1 0 0 1 1 1 1 CDC45-like protein BUD22 PF09073.5 EWM23833.1 - 0.3 10.0 21.6 0.39 9.7 15.0 1.1 1 0 0 1 1 1 0 BUD22 Zip PF02535.17 EWM23833.1 - 0.46 9.4 1.6 0.7 8.8 1.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Tim54 PF11711.3 EWM23833.1 - 1.4 7.3 9.4 2.1 6.8 6.5 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DDHD PF02862.12 EWM23833.1 - 4 7.1 6.8 6.1 6.5 4.7 1.2 1 0 0 1 1 1 0 DDHD domain DUF1510 PF07423.6 EWM23833.1 - 4.7 6.5 22.2 6.6 6.0 15.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Thioredoxin_4 PF13462.1 EWM23834.1 - 1.8e-09 37.8 0.0 2.3e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 EWM23834.1 - 3.1e-09 36.6 0.8 4.1e-07 29.7 0.6 2.1 1 1 0 1 1 1 1 DSBA-like thioredoxin domain EF-hand_7 PF13499.1 EWM23835.1 - 0.00069 19.7 0.0 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair COPI_assoc PF08507.5 EWM23835.1 - 0.0026 17.4 1.3 0.008 15.8 0.3 1.9 2 0 0 2 2 2 1 COPI associated protein DUF202 PF02656.10 EWM23835.1 - 0.046 13.9 0.8 0.14 12.3 0.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF202) EF-hand_8 PF13833.1 EWM23835.1 - 0.047 13.3 0.0 0.086 12.4 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair NDK PF00334.14 EWM23836.1 - 8.6e-54 180.9 0.0 1.1e-53 180.5 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PT PF04886.7 EWM23836.1 - 0.22 10.8 2.5 0.37 10.1 1.8 1.3 1 0 0 1 1 1 0 PT repeat Pro_isomerase PF00160.16 EWM23837.1 - 2.8e-13 50.3 0.0 4.1e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PsbQ PF05757.6 EWM23838.1 - 1.8e-08 34.0 6.3 2.4e-08 33.6 4.4 1.1 1 0 0 1 1 1 1 Oxygen evolving enhancer protein 3 (PsbQ) DUF4327 PF14217.1 EWM23838.1 - 0.00055 19.6 0.1 0.00087 19.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4327) MutS_III PF05192.13 EWM23838.1 - 0.00079 19.2 1.0 0.00098 18.9 0.7 1.1 1 0 0 1 1 1 1 MutS domain III FUSC-like PF12805.2 EWM23838.1 - 0.03 13.2 0.3 0.039 12.8 0.2 1.1 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS DUF724 PF05266.9 EWM23838.1 - 0.062 12.9 2.4 0.081 12.5 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) MAT1 PF06391.8 EWM23839.1 - 2.1e-08 33.9 17.7 3.5e-08 33.2 12.3 1.4 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-RING_5 PF14634.1 EWM23839.1 - 4.7e-06 26.2 6.8 1.2e-05 24.9 4.8 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EWM23839.1 - 1.7e-05 24.5 3.9 3e-05 23.7 2.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EWM23839.1 - 0.00035 20.3 3.0 0.00035 20.3 2.1 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EWM23839.1 - 0.00036 20.5 4.9 0.00036 20.5 3.4 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EWM23839.1 - 0.0012 18.4 5.5 0.0036 16.9 3.9 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EWM23839.1 - 0.0052 16.4 1.3 0.013 15.2 0.6 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 EWM23839.1 - 0.021 14.8 2.0 0.04 14.0 1.4 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger FYVE PF01363.16 EWM23839.1 - 0.13 12.2 4.1 0.27 11.1 2.8 1.6 1 0 0 1 1 1 0 FYVE zinc finger DUF2197 PF09963.4 EWM23839.1 - 0.14 12.1 5.1 0.3 11.0 3.5 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) DUF4472 PF14739.1 EWM23839.1 - 0.25 11.8 8.9 0.56 10.6 6.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) GP38 PF05268.6 EWM23839.1 - 0.7 9.2 9.6 0.98 8.7 6.7 1.2 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 zf-RING_4 PF14570.1 EWM23839.1 - 6.8 6.3 9.3 23 4.6 6.4 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain MAT1 PF06391.8 EWM23840.1 - 2.2e-08 33.9 17.7 3.1e-08 33.4 12.3 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 DUF4472 PF14739.1 EWM23840.1 - 0.25 11.8 8.9 0.51 10.8 6.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) GP38 PF05268.6 EWM23840.1 - 0.64 9.4 9.6 0.87 8.9 6.7 1.2 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 FA_desaturase PF00487.19 EWM23841.1 - 2.4e-37 128.8 12.2 3.9e-37 128.1 8.4 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EWM23841.1 - 5.2e-25 87.0 0.2 2.3e-24 85.0 0.0 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain GSHPx PF00255.14 EWM23842.1 - 5.3e-09 35.4 0.0 7.9e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase HEAT_2 PF13646.1 EWM23843.1 - 0.0061 16.8 2.3 0.0093 16.2 0.4 2.2 2 1 0 2 2 2 1 HEAT repeats HEAT PF02985.17 EWM23843.1 - 0.56 10.4 0.1 0.56 10.4 0.0 2.2 3 0 0 3 3 3 0 HEAT repeat Sec8_exocyst PF04048.9 EWM23844.1 - 0.029 13.9 0.0 0.042 13.4 0.0 1.3 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain HEAT PF02985.17 EWM23846.1 - 6.7e-11 41.3 3.7 5.5e-05 22.9 0.1 3.7 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 EWM23846.1 - 1.1e-08 35.2 0.2 1.2e-06 28.6 0.1 2.2 1 1 1 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 EWM23846.1 - 0.0037 17.7 3.7 0.025 15.0 0.4 3.2 3 1 1 4 4 4 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EWM23846.1 - 0.054 13.8 0.0 0.097 13.0 0.0 1.5 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EWM23847.1 - 0.1 13.1 0.3 0.17 12.4 0.0 1.5 2 0 0 2 2 2 0 HEAT-like repeat PPR_3 PF13812.1 EWM23848.1 - 7.5e-21 72.6 4.1 7.3e-06 25.8 0.0 5.9 6 0 0 6 6 6 4 Pentatricopeptide repeat domain PPR_2 PF13041.1 EWM23848.1 - 8.6e-21 73.6 0.0 4.6e-08 32.9 0.0 4.4 2 1 3 5 5 5 5 PPR repeat family PPR PF01535.15 EWM23848.1 - 1.4e-18 65.5 0.0 0.00037 20.2 0.0 5.9 6 0 0 6 6 6 4 PPR repeat PPR_1 PF12854.2 EWM23848.1 - 1.9e-14 52.8 0.1 0.00027 20.3 0.0 4.8 5 0 0 5 5 5 4 PPR repeat TPR_14 PF13428.1 EWM23848.1 - 5.3e-06 26.6 6.2 0.19 12.4 0.1 5.1 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 EWM23848.1 - 0.0001 22.8 6.2 0.17 12.6 0.0 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat GTP1_OBG PF01018.17 EWM23849.1 - 3.3e-21 75.5 4.0 4.5e-21 75.1 2.8 1.1 1 0 0 1 1 1 1 GTP1/OBG PPR_2 PF13041.1 EWM23851.1 - 3.6e-08 33.2 0.0 9.3e-05 22.3 0.0 3.7 3 1 1 4 4 4 1 PPR repeat family PPR_3 PF13812.1 EWM23851.1 - 7.6e-08 32.0 1.3 0.14 12.4 0.0 4.0 4 0 0 4 4 4 3 Pentatricopeptide repeat domain PPR PF01535.15 EWM23851.1 - 5.2e-05 22.9 0.0 0.72 9.9 0.0 3.5 3 0 0 3 3 3 2 PPR repeat PPR_1 PF12854.2 EWM23851.1 - 0.015 14.7 0.0 0.54 9.7 0.0 2.8 3 0 0 3 3 3 0 PPR repeat STAS_2 PF13466.1 EWM23851.1 - 0.017 15.1 0.1 0.069 13.1 0.0 2.1 2 1 0 2 2 2 0 STAS domain EF1_GNE PF00736.14 EWM23852.1 - 2.7e-30 103.8 0.6 4.8e-30 103.0 0.4 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EWM23852.1 - 0.0029 17.7 0.4 0.0075 16.3 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region Ribosomal_60s PF00428.14 EWM23852.1 - 0.016 15.6 0.5 0.016 15.6 0.4 2.8 3 1 0 3 3 3 0 60s Acidic ribosomal protein DUF2098 PF09871.4 EWM23852.1 - 1.3 8.9 4.2 12 5.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) Nepo_coat PF03391.10 EWM23853.1 - 0.026 13.7 0.1 0.067 12.4 0.0 1.7 2 0 0 2 2 2 0 Nepovirus coat protein, central domain Glyco_hydro_17 PF00332.13 EWM23854.1 - 4.6e-32 111.3 0.0 6.6e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 ATG13 PF10033.4 EWM23855.1 - 7.1e-19 68.1 0.0 1e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 13 His_biosynth PF00977.16 EWM23856.1 - 0.0049 16.1 0.0 0.007 15.6 0.0 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein NAD_binding_1 PF00175.16 EWM23857.1 - 3.6e-27 95.0 0.0 7.1e-27 94.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EWM23857.1 - 7e-05 22.8 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain FAD_binding_1 PF00667.15 EWM23857.1 - 0.0044 16.4 0.1 0.81 9.0 0.0 2.5 3 0 0 3 3 3 2 FAD binding domain NADPH_Ox PF08414.5 EWM23857.1 - 0.089 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Respiratory burst NADPH oxidase 7TM_GPCR_Srz PF10325.4 EWM23857.1 - 0.26 10.3 0.1 0.36 9.9 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srz His_biosynth PF00977.16 EWM23859.1 - 1.8e-09 37.2 0.0 2.3e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Aldolase PF01081.14 EWM23859.1 - 0.0028 16.8 0.0 0.004 16.3 0.0 1.2 1 0 0 1 1 1 1 KDPG and KHG aldolase Ribul_P_3_epim PF00834.14 EWM23859.1 - 0.0071 15.4 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family TMP-TENI PF02581.12 EWM23859.1 - 0.033 13.3 0.1 0.041 12.9 0.0 1.4 1 1 0 1 1 1 0 Thiamine monophosphate synthase/TENI PcrB PF01884.12 EWM23859.1 - 0.065 12.4 0.0 0.088 12.0 0.0 1.4 1 1 0 1 1 1 0 PcrB family PH_11 PF15413.1 EWM23861.1 - 3.4e-05 24.0 0.0 0.00027 21.1 0.0 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EWM23861.1 - 0.00027 21.1 0.0 0.00059 20.0 0.0 1.5 1 1 0 1 1 1 1 PH domain PH_9 PF15410.1 EWM23861.1 - 0.034 14.3 0.0 0.061 13.4 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain HORMA PF02301.13 EWM23863.1 - 2.9e-15 56.3 0.0 3.6e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 HORMA domain Aldo_ket_red PF00248.16 EWM23864.1 - 1.6e-29 102.6 0.0 2.8e-28 98.5 0.0 2.3 1 1 0 1 1 1 1 Aldo/keto reductase family Asp_Glu_race PF01177.17 EWM23864.1 - 0.073 12.9 0.1 1.8 8.4 0.0 2.6 2 1 0 2 2 2 0 Asp/Glu/Hydantoin racemase Herpes_gE PF02480.11 EWM23865.1 - 0.18 10.0 0.0 0.25 9.5 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Mob1_phocein PF03637.12 EWM23866.1 - 1.3e-52 178.0 0.1 1.7e-52 177.6 0.1 1.2 1 0 0 1 1 1 1 Mob1/phocein family Mob1_phocein PF03637.12 EWM23867.1 - 1.3e-52 178.0 0.1 1.7e-52 177.6 0.1 1.2 1 0 0 1 1 1 1 Mob1/phocein family SIR2 PF02146.12 EWM23868.1 - 3.2e-43 147.5 0.0 6.4e-43 146.5 0.0 1.5 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 EWM23868.1 - 0.00044 20.0 0.0 0.14 11.8 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain PNTB PF02233.11 EWM23868.1 - 0.18 10.5 0.1 0.42 9.3 0.0 1.5 2 0 0 2 2 2 0 NAD(P) transhydrogenase beta subunit ABC_tran PF00005.22 EWM23869.1 - 3.2e-38 131.1 0.0 5.3e-19 68.8 0.0 2.3 2 0 0 2 2 2 2 ABC transporter RLI PF04068.10 EWM23869.1 - 1.3e-13 50.2 8.2 3.3e-13 48.9 5.7 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 EWM23869.1 - 1.4e-13 51.4 0.2 0.00076 19.5 0.3 4.4 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 EWM23869.1 - 8.4e-10 38.2 0.1 0.0044 16.2 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EWM23869.1 - 3e-08 33.8 0.0 0.00022 21.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain Fer4 PF00037.22 EWM23869.1 - 4.8e-08 32.2 2.4 4.8e-08 32.2 1.7 2.6 3 0 0 3 3 2 1 4Fe-4S binding domain AAA PF00004.24 EWM23869.1 - 3.3e-06 27.3 0.0 0.12 12.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EWM23869.1 - 3.6e-06 26.4 0.1 0.0092 15.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Fer4_6 PF12837.2 EWM23869.1 - 4.9e-06 26.1 11.7 5.5e-05 22.8 1.0 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain NACHT PF05729.7 EWM23869.1 - 1e-05 25.2 1.1 0.0041 16.7 0.0 2.4 2 0 0 2 2 2 1 NACHT domain MobB PF03205.9 EWM23869.1 - 2.7e-05 23.9 0.2 0.07 12.8 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EWM23869.1 - 4.3e-05 23.4 0.0 0.026 14.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EWM23869.1 - 4.3e-05 23.2 0.0 0.039 13.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EWM23869.1 - 4.4e-05 22.9 0.0 0.3 10.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EWM23869.1 - 4.7e-05 23.8 0.0 0.057 13.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EWM23869.1 - 4.7e-05 23.0 0.1 0.0055 16.3 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 EWM23869.1 - 8.3e-05 23.4 0.0 0.097 13.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 EWM23869.1 - 0.00011 21.4 0.0 2.8 6.8 0.0 3.7 4 0 0 4 4 4 1 AAA ATPase domain DUF258 PF03193.11 EWM23869.1 - 0.00011 21.4 3.0 0.22 10.7 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function, DUF258 SRP54 PF00448.17 EWM23869.1 - 0.00013 21.5 0.8 0.027 13.9 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_30 PF13604.1 EWM23869.1 - 0.00024 20.7 0.3 0.25 10.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EWM23869.1 - 0.00036 20.6 0.0 0.65 10.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_16 PF13191.1 EWM23869.1 - 0.00055 19.9 0.0 0.17 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 EWM23869.1 - 0.00056 20.4 0.0 0.29 11.6 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein Fer4_2 PF12797.2 EWM23869.1 - 0.00061 19.5 1.6 0.00061 19.5 1.1 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.1 EWM23869.1 - 0.00066 19.4 11.8 0.0015 18.3 8.2 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Thymidylate_kin PF02223.12 EWM23869.1 - 0.00068 19.0 0.0 0.55 9.5 0.0 2.5 2 0 0 2 2 2 1 Thymidylate kinase VirE PF05272.6 EWM23869.1 - 0.0015 18.0 0.0 2.4 7.5 0.0 2.6 2 0 0 2 2 2 2 Virulence-associated protein E AAA_18 PF13238.1 EWM23869.1 - 0.0017 18.6 0.1 0.6 10.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain Fer4_7 PF12838.2 EWM23869.1 - 0.0024 18.1 2.0 0.0024 18.1 1.4 2.4 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EWM23869.1 - 0.0034 17.1 1.4 0.0034 17.1 1.0 2.2 1 1 1 2 2 2 1 4Fe-4S dicluster domain AAA_19 PF13245.1 EWM23869.1 - 0.0054 16.4 0.3 1.5 8.6 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain Fer4_9 PF13187.1 EWM23869.1 - 0.0061 16.8 12.5 0.017 15.4 8.7 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_13 PF13166.1 EWM23869.1 - 0.01 14.3 0.0 0.36 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EWM23869.1 - 0.012 14.5 0.1 0.26 10.1 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Fer4_16 PF13484.1 EWM23869.1 - 0.014 16.1 0.2 0.014 16.1 0.1 2.6 2 1 1 3 3 1 0 4Fe-4S double cluster binding domain Fer4_3 PF12798.2 EWM23869.1 - 0.017 15.6 4.3 0.017 15.6 3.0 2.5 2 0 0 2 2 1 0 4Fe-4S binding domain Rad17 PF03215.10 EWM23869.1 - 0.019 13.6 0.0 0.16 10.5 0.0 2.0 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 EWM23869.1 - 0.029 14.2 0.0 7.8 6.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain Fer4_4 PF12800.2 EWM23869.1 - 0.029 14.6 2.3 0.029 14.6 1.6 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain DUF815 PF05673.8 EWM23869.1 - 0.036 12.9 0.1 6.8 5.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) SbcCD_C PF13558.1 EWM23869.1 - 0.041 13.8 0.0 12 5.8 0.0 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.1 EWM23869.1 - 0.043 13.4 0.2 1 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EWM23869.1 - 0.051 13.2 1.3 3.3 7.3 0.0 2.9 3 0 0 3 3 2 0 NTPase Fer4_8 PF13183.1 EWM23869.1 - 0.053 13.5 8.8 0.12 12.4 6.1 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Zeta_toxin PF06414.7 EWM23869.1 - 0.053 12.6 0.1 6.3 5.8 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.13 EWM23869.1 - 0.056 12.9 0.1 3 7.2 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_28 PF13521.1 EWM23869.1 - 0.063 13.2 0.1 4 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 EWM23869.1 - 0.11 11.4 0.0 9.6 5.0 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain Septin PF00735.13 EWM23869.1 - 0.13 11.2 0.1 1.3 7.9 0.0 2.1 2 0 0 2 2 2 0 Septin Fer4_15 PF13459.1 EWM23869.1 - 1.8 9.1 8.0 0.13 12.8 0.7 2.7 2 0 0 2 2 1 0 4Fe-4S single cluster domain ABC_tran PF00005.22 EWM23870.1 - 1.1e-27 97.0 0.0 1.9e-16 60.5 0.0 2.3 2 0 0 2 2 2 2 ABC transporter RLI PF04068.10 EWM23870.1 - 9.5e-14 50.6 8.2 2.5e-13 49.3 5.7 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 EWM23870.1 - 1e-10 42.0 0.2 0.00053 20.0 0.4 3.1 2 1 0 2 2 2 2 AAA domain Fer4 PF00037.22 EWM23870.1 - 3.6e-08 32.6 2.4 3.6e-08 32.6 1.7 2.7 3 0 0 3 3 2 1 4Fe-4S binding domain AAA_22 PF13401.1 EWM23870.1 - 5.4e-07 29.8 0.0 0.005 16.9 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA PF00004.24 EWM23870.1 - 2.1e-06 27.9 0.0 0.094 12.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EWM23870.1 - 2.3e-06 27.0 0.1 0.0069 15.8 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain Fer4_6 PF12837.2 EWM23870.1 - 3e-06 26.8 11.7 4.2e-05 23.2 1.0 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain NACHT PF05729.7 EWM23870.1 - 4.7e-06 26.3 0.7 0.0031 17.1 0.0 2.4 2 0 0 2 2 2 1 NACHT domain MobB PF03205.9 EWM23870.1 - 2e-05 24.3 0.2 0.053 13.2 0.0 2.4 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EWM23870.1 - 2.4e-05 23.8 0.0 0.21 10.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EWM23870.1 - 2.6e-05 24.1 0.0 0.02 14.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EWM23870.1 - 2.8e-05 23.7 0.1 0.0041 16.7 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 EWM23870.1 - 3.1e-05 24.4 0.0 0.043 14.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EWM23870.1 - 3.9e-05 22.8 2.6 0.16 11.1 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_5 PF07728.9 EWM23870.1 - 4.8e-05 23.0 0.1 0.029 14.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EWM23870.1 - 5.9e-05 23.8 0.1 0.069 13.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain SRP54 PF00448.17 EWM23870.1 - 7.7e-05 22.2 0.8 0.02 14.3 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SMC_N PF02463.14 EWM23870.1 - 9.9e-05 21.6 0.0 2 7.5 0.0 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.1 EWM23870.1 - 0.00015 21.4 0.3 0.19 11.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EWM23870.1 - 0.00021 21.4 0.0 0.49 10.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_16 PF13191.1 EWM23870.1 - 0.00036 20.5 0.0 0.14 12.1 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 EWM23870.1 - 0.00037 20.9 0.0 0.23 11.9 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein Fer4_2 PF12797.2 EWM23870.1 - 0.00046 19.9 1.6 0.00046 19.9 1.1 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Thymidylate_kin PF02223.12 EWM23870.1 - 0.00051 19.4 0.0 0.4 10.0 0.0 2.3 2 0 0 2 2 2 1 Thymidylate kinase Fer4_21 PF14697.1 EWM23870.1 - 0.00057 19.6 11.8 0.0011 18.7 8.2 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain VirE PF05272.6 EWM23870.1 - 0.0011 18.4 0.0 1.8 8.0 0.0 2.3 2 0 0 2 2 2 2 Virulence-associated protein E AAA_18 PF13238.1 EWM23870.1 - 0.0012 19.1 0.0 0.43 10.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4_7 PF12838.2 EWM23870.1 - 0.0019 18.5 1.9 0.0019 18.5 1.3 2.4 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EWM23870.1 - 0.0024 17.6 1.3 0.0024 17.6 0.9 2.2 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EWM23870.1 - 0.0032 17.6 12.1 0.0088 16.2 8.4 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain AAA_19 PF13245.1 EWM23870.1 - 0.0046 16.6 0.8 1.1 9.0 0.0 2.7 3 0 0 3 3 2 1 Part of AAA domain T2SE PF00437.15 EWM23870.1 - 0.007 15.3 0.1 0.19 10.6 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_13 PF13166.1 EWM23870.1 - 0.0071 14.8 0.0 0.27 9.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain Fer4_16 PF13484.1 EWM23870.1 - 0.01 16.5 0.2 0.01 16.5 0.1 2.6 2 1 1 3 3 1 0 4Fe-4S double cluster binding domain AAA_15 PF13175.1 EWM23870.1 - 0.011 14.8 0.0 2.1 7.3 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain Rad17 PF03215.10 EWM23870.1 - 0.011 14.3 0.0 0.12 11.0 0.0 2.0 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Fer4_3 PF12798.2 EWM23870.1 - 0.013 15.9 4.3 0.013 15.9 3.0 2.4 2 0 0 2 2 1 0 4Fe-4S binding domain DUF815 PF05673.8 EWM23870.1 - 0.022 13.7 0.1 5.1 5.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 EWM23870.1 - 0.022 14.6 0.0 5.8 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Fer4_4 PF12800.2 EWM23870.1 - 0.022 15.0 2.3 0.022 15.0 1.6 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain AAA_24 PF13479.1 EWM23870.1 - 0.027 14.0 0.2 0.79 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Fer4_8 PF13183.1 EWM23870.1 - 0.028 14.4 8.4 0.067 13.2 5.8 1.6 1 1 0 1 1 1 0 4Fe-4S dicluster domain FtsK_SpoIIIE PF01580.13 EWM23870.1 - 0.035 13.5 0.1 2.2 7.6 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 EWM23870.1 - 0.037 13.1 0.1 4.8 6.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.10 EWM23870.1 - 0.038 13.7 1.5 2.5 7.7 0.0 2.8 3 0 0 3 3 2 0 NTPase AAA_28 PF13521.1 EWM23870.1 - 0.043 13.7 0.1 3 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 EWM23870.1 - 0.076 11.9 0.0 6.5 5.6 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain Septin PF00735.13 EWM23870.1 - 0.088 11.8 0.1 0.96 8.3 0.0 2.1 2 0 0 2 2 2 0 Septin PhoH PF02562.11 EWM23870.1 - 0.11 11.7 0.1 0.77 8.9 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.16 EWM23870.1 - 0.11 11.6 0.3 0.95 8.5 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EWM23870.1 - 0.14 11.6 0.1 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.17 EWM23870.1 - 0.16 10.8 0.0 8.6 5.1 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain KaiC PF06745.8 EWM23870.1 - 0.16 11.0 0.2 1.2 8.2 0.0 2.0 2 0 0 2 2 2 0 KaiC ArgK PF03308.11 EWM23870.1 - 0.16 10.7 0.3 2.1 7.0 0.1 2.3 2 0 0 2 2 2 0 ArgK protein AAA_10 PF12846.2 EWM23870.1 - 0.22 10.9 0.7 13 5.1 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain Fer4_15 PF13459.1 EWM23870.1 - 1.2 9.7 8.0 0.1 13.1 0.7 2.7 2 0 0 2 2 1 0 4Fe-4S single cluster domain DUF155 PF02582.9 EWM23871.1 - 2.8e-19 69.7 0.0 3.7e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Hs1pro-1_N PF07231.7 EWM23873.1 - 1.1e-05 25.1 0.0 2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Hs1pro-1 N-terminus DUF1681 PF07933.9 EWM23874.1 - 4.4e-48 162.8 0.0 5.7e-48 162.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) PP2C PF00481.16 EWM23875.1 - 3.7e-46 157.5 0.0 7.5e-45 153.3 0.0 2.3 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EWM23875.1 - 4.4e-05 22.9 0.0 0.00025 20.5 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EWM23875.1 - 0.078 12.6 0.1 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EWM23876.1 - 0.0089 15.4 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 EWM23877.1 - 5.5e-15 55.4 0.0 7e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EWM23877.1 - 0.0033 17.1 0.0 0.0045 16.7 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Ribosomal_L29 PF00831.18 EWM23878.1 - 3.1e-21 74.8 3.3 3.1e-21 74.8 2.3 2.0 2 1 0 2 2 2 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 EWM23878.1 - 0.0011 19.2 3.2 0.0013 18.9 2.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DUF2362 PF10154.4 EWM23878.1 - 0.097 11.3 0.3 0.098 11.3 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) eIF3_N PF09440.5 EWM23878.1 - 0.44 10.7 4.3 2.3 8.3 0.1 2.1 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain Prefoldin PF02996.12 EWM23878.1 - 1.1 8.9 7.6 2.6 7.6 1.9 2.5 2 1 1 3 3 3 0 Prefoldin subunit Snapin_Pallidin PF14712.1 EWM23878.1 - 3.2 8.1 7.3 1.5 9.1 2.3 2.0 1 1 1 2 2 2 0 Snapin/Pallidin Peptidase_A21 PF03566.8 EWM23880.1 - 0.49 8.4 3.2 0.41 8.6 2.2 1.0 1 0 0 1 1 1 0 Peptidase family A21 DUF1127 PF06568.6 EWM23880.1 - 0.64 9.4 11.5 1.4 8.3 8.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) zf-TFIIIC PF12660.2 EWM23882.1 - 3.3e-08 33.3 1.8 6.1e-08 32.4 1.2 1.4 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex zf-MIZ PF02891.15 EWM23882.1 - 0.074 12.5 0.3 0.074 12.5 0.2 2.1 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-Sec23_Sec24 PF04810.10 EWM23882.1 - 0.17 11.5 0.1 0.17 11.5 0.0 2.4 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger YdjO PF14169.1 EWM23882.1 - 0.28 10.6 2.6 14 5.1 0.0 2.9 3 0 0 3 3 3 0 Cold-inducible protein YdjO PHF5 PF03660.9 EWM23882.1 - 0.93 9.5 4.6 0.47 10.5 1.3 1.9 2 1 0 2 2 2 0 PHF5-like protein DUF1713 PF08213.6 EWM23883.1 - 7.3e-07 28.6 21.5 1.1e-06 28.0 14.9 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Pep3_Vps18 PF05131.9 EWM23884.1 - 2.3e-08 33.5 0.0 3.5e-07 29.7 0.0 2.6 2 1 0 2 2 2 1 Pep3/Vps18/deep orange family Vps39_2 PF10367.4 EWM23884.1 - 0.00062 19.9 0.1 0.0014 18.8 0.1 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.1 EWM23884.1 - 0.003 17.3 6.5 0.0098 15.7 4.5 1.9 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EWM23884.1 - 0.068 12.9 5.2 0.059 13.1 1.9 2.0 2 0 0 2 2 2 0 zinc-RING finger domain CCG PF02754.11 EWM23884.1 - 0.13 12.3 0.1 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Cysteine-rich domain zf-C3HC4_3 PF13920.1 EWM23884.1 - 1.4 8.6 3.4 2.2 8.0 1.0 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EWM23884.1 - 1.7 8.7 6.1 0.63 10.1 1.9 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EWM23884.1 - 6 6.6 7.3 0.47 10.1 1.7 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MFS_1 PF07690.11 EWM23885.1 - 1.4e-24 86.5 30.7 1.8e-20 72.9 11.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EWM23885.1 - 3.6e-24 85.1 18.1 1.9e-22 79.4 12.5 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 EWM23885.1 - 8.6e-07 27.6 11.7 0.00031 19.2 7.5 2.5 2 1 1 3 3 3 2 MFS/sugar transport protein O-antigen_lig PF13425.1 EWM23885.1 - 0.00069 19.6 1.9 0.00069 19.6 1.3 3.5 4 0 0 4 4 4 1 O-antigen ligase like membrane protein DoxX_2 PF13564.1 EWM23885.1 - 0.23 11.4 0.2 0.23 11.4 0.1 3.3 3 2 1 4 4 4 0 DoxX-like family Zip PF02535.17 EWM23886.1 - 4.4e-17 62.0 6.6 4.4e-17 62.0 4.5 2.9 1 1 2 3 3 3 2 ZIP Zinc transporter DUF2061 PF09834.4 EWM23887.1 - 4.2e-19 68.4 4.5 5.2e-10 39.3 1.1 2.3 2 0 0 2 2 2 2 Predicted membrane protein (DUF2061) La PF05383.12 EWM23888.1 - 1.5e-18 66.2 0.0 2.3e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 La domain DUF1313 PF07011.6 EWM23889.1 - 1e-07 31.5 0.5 0.01 15.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1313) ENTH PF01417.15 EWM23890.1 - 3.8e-23 81.7 0.1 5.4e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 ENTH domain VHS PF00790.14 EWM23890.1 - 0.011 15.3 0.0 0.024 14.2 0.0 1.6 1 1 0 1 1 1 0 VHS domain Phage_tail_U PF06141.6 EWM23890.1 - 0.052 13.5 0.1 0.071 13.1 0.0 1.3 1 0 0 1 1 1 0 Phage minor tail protein U DUF501 PF04417.7 EWM23891.1 - 8.3e-26 90.4 1.1 1.7e-25 89.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF501) PRP4 PF08799.6 EWM23891.1 - 1.3 8.3 6.6 1.3 8.3 0.1 2.8 3 0 0 3 3 3 0 pre-mRNA processing factor 4 (PRP4) like Amino_oxidase PF01593.19 EWM23892.1 - 1e-71 242.3 0.0 1.2e-71 242.1 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EWM23892.1 - 7.9e-15 54.6 0.0 1.9e-14 53.4 0.0 1.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EWM23892.1 - 4.6e-08 32.3 0.0 0.00031 19.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 EWM23892.1 - 0.00022 20.4 0.1 0.00043 19.4 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 EWM23892.1 - 0.00057 19.9 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EWM23892.1 - 0.0014 17.7 0.1 0.0024 17.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 EWM23892.1 - 0.0018 17.1 0.2 0.0043 15.9 0.2 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EWM23892.1 - 0.0061 16.4 0.1 0.017 15.0 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EWM23892.1 - 0.016 15.6 0.0 0.37 11.2 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EWM23892.1 - 0.26 9.7 0.2 0.48 8.8 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_7 PF03441.9 EWM23893.1 - 1.4e-97 326.2 0.1 1.8e-97 325.8 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EWM23893.1 - 4.1e-45 153.5 0.0 7.3e-45 152.6 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Sugar_tr PF00083.19 EWM23895.1 - 1.4e-35 122.7 29.6 8.7e-25 87.2 6.6 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EWM23895.1 - 3.7e-21 75.2 31.2 3.1e-19 68.8 20.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.11 EWM23895.1 - 0.0012 17.6 0.5 0.0018 17.0 0.3 1.3 1 0 0 1 1 1 1 BT1 family Ring_hydroxyl_A PF00848.14 EWM23896.1 - 2.3e-29 102.5 0.0 3.3e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 EWM23896.1 - 1.8e-15 56.2 0.0 3.8e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ribosomal_S13 PF00416.17 EWM23897.1 - 1.7e-38 131.3 1.1 2.5e-38 130.8 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EWM23897.1 - 0.01 14.4 0.0 0.013 14.0 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF4004 PF13171.1 EWM23897.1 - 0.023 14.8 0.0 0.038 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4004) Glyoxalase PF00903.20 EWM23898.1 - 5.2e-09 36.1 0.0 0.00065 19.6 0.0 2.8 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EWM23898.1 - 6e-07 29.4 0.0 0.0013 18.7 0.0 2.8 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.1 EWM23898.1 - 9e-06 25.6 0.0 4.7e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.1 EWM23898.1 - 0.0068 16.3 0.1 5.8 6.7 0.0 3.7 4 0 0 4 4 4 1 Glyoxalase-like domain Lysine_decarbox PF03641.9 EWM23899.1 - 4.7e-20 71.7 0.0 6.2e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase OB_NTP_bind PF07717.11 EWM23901.1 - 7.2e-17 61.2 0.0 1.8e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EWM23901.1 - 2.6e-12 46.6 0.0 6.5e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EWM23901.1 - 1.8e-08 34.1 0.0 5.1e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EWM23901.1 - 1.2e-05 24.8 0.2 0.0064 16.0 0.0 2.6 3 0 0 3 3 3 2 DEAD/DEAH box helicase AAA_22 PF13401.1 EWM23901.1 - 8.4e-05 22.7 0.1 0.0004 20.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.9 EWM23901.1 - 0.0032 17.2 0.0 0.0075 16.0 0.0 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain FtsK_SpoIIIE PF01580.13 EWM23901.1 - 0.0054 16.2 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_29 PF13555.1 EWM23901.1 - 0.0099 15.3 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ResIII PF04851.10 EWM23901.1 - 0.024 14.4 0.0 3.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit T2SE PF00437.15 EWM23901.1 - 0.03 13.2 0.0 0.054 12.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.22 EWM23901.1 - 0.047 13.9 0.0 0.17 12.2 0.0 2.0 1 1 0 1 1 1 0 ABC transporter G-alpha PF00503.15 EWM23901.1 - 0.067 11.8 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_25 PF13481.1 EWM23901.1 - 0.089 12.1 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EWM23901.1 - 0.16 11.3 0.1 5.9 6.2 0.0 2.7 3 0 0 3 3 3 0 AAA-like domain Mago_nashi PF02792.9 EWM23902.1 - 1.1e-73 245.6 0.2 1.2e-73 245.4 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein RRM_1 PF00076.17 EWM23903.1 - 7.1e-14 51.2 0.0 1.1e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM23903.1 - 1.1e-09 38.1 0.0 1.8e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM23903.1 - 1.9e-05 24.4 0.0 3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FabA PF07977.8 EWM23904.1 - 1.3e-40 138.1 0.1 1.6e-40 137.7 0.1 1.1 1 0 0 1 1 1 1 FabA-like domain MaoC_dehydratas PF01575.14 EWM23904.1 - 0.0012 18.1 0.0 0.0019 17.5 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain 4HBT PF03061.17 EWM23904.1 - 0.059 13.5 0.0 0.18 11.9 0.0 1.8 1 1 0 1 1 1 0 Thioesterase superfamily FBPase PF00316.15 EWM23906.1 - 2.4e-64 217.1 0.0 3.3e-64 216.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase CRAL_TRIO PF00650.15 EWM23907.1 - 2.9e-28 98.3 0.0 3.7e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EWM23907.1 - 9e-05 22.4 0.0 0.00014 21.8 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Sugar_tr PF00083.19 EWM23908.1 - 2.5e-40 138.4 25.0 7e-28 97.3 6.7 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EWM23908.1 - 1.9e-37 128.8 38.8 5.2e-31 107.6 18.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EWM23908.1 - 8.3e-10 37.6 21.0 0.00066 18.1 5.8 3.1 2 1 1 3 3 3 3 MFS/sugar transport protein BT1 PF03092.11 EWM23908.1 - 2.5e-06 26.4 0.5 4.5e-06 25.6 0.3 1.5 1 0 0 1 1 1 1 BT1 family TRI12 PF06609.8 EWM23908.1 - 0.00059 18.1 2.1 0.0047 15.1 0.3 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) KH_1 PF00013.24 EWM23909.1 - 4.4e-36 122.3 1.5 3.5e-12 45.7 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EWM23909.1 - 2.7e-33 113.0 6.7 4.3e-11 42.1 0.5 3.6 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EWM23909.1 - 2.6e-10 39.6 3.6 0.0024 17.3 0.3 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EWM23909.1 - 6.3e-06 25.7 1.6 0.034 13.8 0.2 3.5 3 1 0 3 3 3 2 KH domain KH_5 PF13184.1 EWM23909.1 - 0.049 13.4 1.1 5.7 6.8 0.0 3.1 3 0 0 3 3 3 0 NusA-like KH domain Reprolysin_2 PF13574.1 EWM23910.1 - 0.001 19.1 0.1 0.001 19.1 0.0 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EWM23910.1 - 0.0013 18.2 0.1 0.0013 18.2 0.0 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.8 EWM23910.1 - 0.0056 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EWM23910.1 - 0.0057 16.5 0.0 0.0057 16.5 0.0 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12 PDGF_N PF04692.8 EWM23910.1 - 0.032 14.7 0.9 0.15 12.5 0.1 2.3 2 0 0 2 2 2 0 Platelet-derived growth factor, N terminal region Astacin PF01400.19 EWM23910.1 - 0.06 12.7 0.3 2.2 7.6 0.1 2.2 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) DUF1025 PF06262.6 EWM23910.1 - 0.06 13.1 0.0 0.21 11.4 0.0 1.9 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase Peptidase_M66 PF10462.4 EWM23910.1 - 0.1 11.4 0.1 0.18 10.6 0.1 1.3 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M10 PF00413.19 EWM23910.1 - 0.13 11.9 5.8 0.43 10.2 4.0 1.9 1 1 0 1 1 1 0 Matrixin Spore_III_AE PF09546.5 EWM23910.1 - 0.33 9.8 0.0 0.49 9.2 0.0 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AE (spore_III_AE) Polyketide_cyc PF03364.15 EWM23911.1 - 0.096 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Fe_bilin_red PF05996.7 EWM23912.1 - 1.7e-53 181.4 0.1 2.2e-53 181.0 0.1 1.1 1 0 0 1 1 1 1 Ferredoxin-dependent bilin reductase Pribosyltran PF00156.22 EWM23913.1 - 2.5e-18 66.0 0.0 3.3e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EWM23913.1 - 9.5e-05 21.6 0.0 0.00012 21.3 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase ATP-synt_ab PF00006.20 EWM23914.1 - 6e-61 205.6 0.0 8.1e-61 205.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EWM23914.1 - 3.8e-13 49.9 0.0 7.7e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EWM23914.1 - 6.8e-11 42.2 0.6 1.6e-10 41.0 0.4 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EWM23914.1 - 0.059 13.2 0.2 0.13 12.1 0.2 1.6 1 0 0 1 1 1 0 HAS barrel domain DUF561 PF04481.7 EWM23914.1 - 0.17 10.7 0.0 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF561) Metallophos PF00149.23 EWM23915.1 - 1.3e-37 129.1 0.1 1.6e-37 128.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rubis-subs-bind PF09273.6 EWM23916.1 - 0.00012 21.9 0.0 0.00042 20.2 0.0 1.9 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding SET PF00856.23 EWM23916.1 - 0.0042 17.4 0.0 0.25 11.6 0.0 2.4 2 0 0 2 2 2 1 SET domain DUF3727 PF12527.3 EWM23917.1 - 1.3e-06 28.4 13.4 0.00045 20.2 0.1 3.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3727) Daxx PF03344.10 EWM23917.1 - 7.3 4.9 9.0 9 4.6 6.2 1.2 1 0 0 1 1 1 0 Daxx Family DUF1275 PF06912.6 EWM23918.1 - 3.2e-31 108.1 21.0 4.1e-31 107.8 14.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Mem_trans PF03547.13 EWM23919.1 - 3e-14 52.1 15.8 4.5e-10 38.3 1.2 2.1 2 0 0 2 2 2 2 Membrane transport protein Mem_trans PF03547.13 EWM23920.1 - 3.4e-14 51.9 15.8 4.8e-10 38.2 1.2 2.1 2 0 0 2 2 2 2 Membrane transport protein HECT PF00632.20 EWM23921.1 - 2.2e-68 230.7 0.0 2.8e-68 230.4 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) CK2S PF15011.1 EWM23921.1 - 0.02 14.7 1.2 0.46 10.2 0.0 2.9 3 0 0 3 3 3 0 Casein Kinase 2 substrate BAF1_ABF1 PF04684.8 EWM23921.1 - 1.3 7.7 5.4 1.9 7.2 3.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DHDPS PF00701.17 EWM23922.1 - 1.6e-91 305.9 0.0 1.8e-91 305.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PA PF02225.17 EWM23922.1 - 0.06 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 PA domain US22 PF02393.11 EWM23922.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.6 1 1 0 1 1 1 0 US22 like PIG-H PF10181.4 EWM23923.1 - 1.2e-16 60.1 0.2 2.2e-16 59.2 0.1 1.5 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component DUF2339 PF10101.4 EWM23923.1 - 0.017 13.4 0.1 0.021 13.1 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) Aldo_ket_red PF00248.16 EWM23924.1 - 3.2e-26 91.8 0.0 5.4e-25 87.7 0.0 2.3 2 0 0 2 2 2 2 Aldo/keto reductase family LANC_like PF05147.8 EWM23925.1 - 9.1e-65 218.5 0.0 1.2e-64 218.0 0.0 1.1 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein C5-epim_C PF06662.8 EWM23925.1 - 0.087 12.1 0.1 0.71 9.1 0.0 1.9 1 1 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus TPR_MLP1_2 PF07926.7 EWM23926.1 - 0.084 12.6 0.6 0.13 12.0 0.4 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Solute_trans_a PF03619.11 EWM23927.1 - 6.2e-93 311.0 8.4 7.2e-93 310.8 5.9 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha AvrRpt-cleavage PF05627.6 EWM23927.1 - 0.018 14.0 0.0 0.14 11.2 0.0 2.1 2 0 0 2 2 2 0 Cleavage site for pathogenic type III effector avirulence factor Avr Phtf-FEM1B_bdg PF12129.3 EWM23927.1 - 0.12 11.7 0.5 0.32 10.3 0.4 1.7 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor DUF4407 PF14362.1 EWM23927.1 - 0.14 11.0 2.2 0.23 10.3 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PDZ PF00595.19 EWM23928.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) PRK PF00485.13 EWM23929.1 - 2.7e-43 147.8 0.0 3.6e-43 147.3 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 EWM23929.1 - 1.3e-06 29.1 0.2 3.1e-06 28.0 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EWM23929.1 - 5.5e-06 26.7 0.2 1.4e-05 25.4 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EWM23929.1 - 0.00012 21.9 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EWM23929.1 - 0.00033 20.7 0.1 0.001 19.0 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 EWM23929.1 - 0.0059 15.7 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 EWM23929.1 - 0.015 15.3 0.1 0.07 13.0 0.1 2.1 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 EWM23929.1 - 0.018 14.5 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Sigma54_activat PF00158.21 EWM23929.1 - 0.021 14.2 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 EWM23929.1 - 0.022 14.4 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain FtsK_SpoIIIE PF01580.13 EWM23929.1 - 0.025 14.0 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family UPF0079 PF02367.12 EWM23929.1 - 0.026 14.1 0.1 0.058 13.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 EWM23929.1 - 0.03 14.6 0.0 0.057 13.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Thymidylate_kin PF02223.12 EWM23929.1 - 0.035 13.4 0.1 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 Thymidylate kinase MobB PF03205.9 EWM23929.1 - 0.04 13.6 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CobU PF02283.11 EWM23929.1 - 0.04 13.3 0.2 0.12 11.8 0.1 1.7 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Pox_A32 PF04665.7 EWM23929.1 - 0.045 13.0 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein KaiC PF06745.8 EWM23929.1 - 0.048 12.7 0.0 0.093 11.8 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.1 EWM23929.1 - 0.048 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EWM23929.1 - 0.05 12.4 0.0 0.087 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein APS_kinase PF01583.15 EWM23929.1 - 0.084 12.5 0.0 0.2 11.2 0.0 1.6 2 0 0 2 2 2 0 Adenylylsulphate kinase KTI12 PF08433.5 EWM23929.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CoaE PF01121.15 EWM23929.1 - 0.14 11.5 0.6 1.7 8.0 0.0 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_30 PF13604.1 EWM23929.1 - 0.16 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EWM23929.1 - 0.17 12.0 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase TIL PF01826.12 EWM23930.1 - 1.5 8.9 7.1 7.6 6.7 4.9 2.0 1 1 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain UCR_Fe-S_N PF10399.4 EWM23931.1 - 1.3 8.2 4.3 2 7.6 0.0 2.7 2 1 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal S1 PF00575.18 EWM23932.1 - 2.3e-70 232.6 17.6 6.5e-15 54.9 0.3 15.6 16 0 0 16 16 16 11 S1 RNA binding domain TPR_19 PF14559.1 EWM23932.1 - 8.7e-08 32.3 0.1 1.3 9.3 0.1 4.2 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 EWM23932.1 - 1.7e-07 31.6 2.5 0.56 10.9 0.2 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 EWM23932.1 - 2.5e-07 30.7 8.1 1.4 9.7 0.0 6.7 4 2 3 7 7 7 2 Tetratricopeptide repeat EXOSC1 PF10447.4 EWM23932.1 - 4.9e-05 23.2 1.3 0.9 9.5 0.0 5.6 6 1 0 6 6 6 2 Exosome component EXOSC1/CSL4 Suf PF05843.9 EWM23932.1 - 0.0015 18.2 8.6 0.074 12.7 0.0 2.7 3 0 0 3 3 3 2 Suppressor of forked protein (Suf) NRDE-2 PF08424.5 EWM23932.1 - 0.0023 16.8 1.6 0.0045 15.9 1.1 1.4 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference PPR_3 PF13812.1 EWM23932.1 - 0.046 14.0 0.0 0.36 11.2 0.0 2.7 1 0 0 1 1 1 0 Pentatricopeptide repeat domain TPR_6 PF13174.1 EWM23932.1 - 0.066 13.6 1.4 9.3 6.9 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR PF01535.15 EWM23932.1 - 0.079 12.9 0.3 24 5.1 0.0 3.3 2 0 0 2 2 2 0 PPR repeat Apc3 PF12895.2 EWM23932.1 - 0.14 12.3 0.5 4.2 7.5 0.1 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EWM23932.1 - 0.37 10.7 6.2 8.7 6.3 0.1 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.4 EWM23932.1 - 0.61 9.4 2.3 7.5 5.8 0.1 2.9 2 1 1 3 3 3 0 26S proteasome subunit RPN7 FAD-oxidase_C PF02913.14 EWM23933.1 - 1.3e-55 188.4 0.2 1.9e-55 187.8 0.1 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EWM23933.1 - 1.8e-34 118.1 0.0 4.5e-34 116.9 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain Methyltransf_16 PF10294.4 EWM23934.1 - 3.5e-10 39.6 0.0 8.4e-07 28.6 0.0 2.2 1 1 1 2 2 2 2 Putative methyltransferase Cons_hypoth95 PF03602.10 EWM23934.1 - 0.073 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Paf67 PF10255.4 EWM23936.1 - 4.2e-81 272.9 0.0 9.6e-80 268.4 0.0 2.2 1 1 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_1 PF00515.23 EWM23936.1 - 0.027 14.0 0.0 0.13 11.9 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EWM23936.1 - 0.06 13.2 0.1 0.74 9.7 0.0 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EWM23936.1 - 0.089 12.7 0.0 0.64 10.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2813 PF11398.3 EWM23936.1 - 0.32 10.0 5.6 2.3 7.1 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) Sec5 PF15469.1 EWM23937.1 - 9e-23 80.9 0.1 2.5e-22 79.4 0.1 1.8 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.6 EWM23937.1 - 3.8e-22 77.9 4.3 1e-21 76.5 2.4 2.2 2 0 0 2 2 2 1 Vps51/Vps67 Dor1 PF04124.7 EWM23937.1 - 3.5e-11 42.1 2.9 6.1e-11 41.3 2.0 1.4 1 0 0 1 1 1 1 Dor1-like family DUF2450 PF10475.4 EWM23937.1 - 6.1e-09 35.2 4.3 1.2e-08 34.2 3.0 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 EWM23937.1 - 4e-06 26.7 5.2 2.8e-05 24.0 1.9 2.9 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Zw10 PF06248.8 EWM23937.1 - 0.018 13.1 0.5 0.03 12.4 0.3 1.2 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 LIF_OSM PF01291.12 EWM23937.1 - 0.021 14.7 0.2 0.053 13.4 0.1 1.6 1 0 0 1 1 1 0 LIF / OSM family Vps53_N PF04100.7 EWM23937.1 - 0.037 12.7 1.1 0.096 11.4 0.8 1.7 1 1 0 1 1 1 0 Vps53-like, N-terminal WXG100 PF06013.7 EWM23937.1 - 0.094 12.7 1.2 6.6 6.8 0.1 3.6 3 0 0 3 3 3 0 Proteins of 100 residues with WXG DUF948 PF06103.6 EWM23937.1 - 0.72 9.7 4.1 2.7 7.9 0.1 3.4 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) ABC_membrane PF00664.18 EWM23938.1 - 2.2e-48 165.0 3.9 2.2e-48 165.0 2.7 2.0 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.22 EWM23938.1 - 8.3e-29 100.6 0.0 2.3e-28 99.2 0.0 1.8 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.14 EWM23938.1 - 6.1e-06 25.6 0.0 0.0003 20.1 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EWM23938.1 - 8.7e-05 22.5 0.0 0.00026 21.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain ABC_membrane_3 PF13748.1 EWM23938.1 - 0.00042 19.4 3.7 0.0016 17.4 2.6 2.0 1 1 0 1 1 1 1 ABC transporter transmembrane region AAA_22 PF13401.1 EWM23938.1 - 0.0043 17.1 0.0 0.031 14.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EWM23938.1 - 0.069 12.5 0.1 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EWM23938.1 - 0.088 12.3 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 EWM23938.1 - 0.1 11.7 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EWM23938.1 - 0.11 12.3 0.1 0.44 10.5 0.1 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 EWM23938.1 - 0.12 11.4 0.0 0.31 10.1 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DUF2207 PF09972.4 EWM23938.1 - 0.29 9.6 0.1 14 4.1 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) TAFII55_N PF04658.8 EWM23939.1 - 2.2e-23 82.5 0.0 3e-22 78.8 0.0 2.1 2 0 0 2 2 2 1 TAFII55 protein conserved region DEAD PF00270.24 EWM23940.1 - 3.9e-44 150.1 0.0 8.9e-44 148.9 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EWM23940.1 - 3.9e-19 68.2 0.2 7.9e-19 67.3 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EWM23940.1 - 6.2e-05 22.8 0.0 0.00014 21.7 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EWM23940.1 - 0.011 15.4 0.0 0.1 12.3 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 EWM23940.1 - 0.087 12.9 0.1 0.27 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain BAF1_ABF1 PF04684.8 EWM23940.1 - 0.44 9.3 7.4 0.69 8.6 5.2 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Glyco_transf_90 PF05686.7 EWM23941.1 - 1.4e-19 70.0 1.5 1.2e-16 60.4 0.4 3.0 2 1 0 2 2 2 2 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 EWM23941.1 - 0.038 14.2 0.0 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferases group 1 LINES_N PF14694.1 EWM23942.1 - 6.5e-06 25.6 0.2 1.1e-05 24.8 0.2 1.3 1 0 0 1 1 1 1 Lines N-terminus LINES_C PF14695.1 EWM23942.1 - 0.0077 15.4 1.1 0.015 14.5 0.1 2.0 2 0 0 2 2 2 1 Lines C-terminus MTBP_mid PF14919.1 EWM23942.1 - 0.034 12.8 0.0 0.056 12.1 0.0 1.2 1 0 0 1 1 1 0 MDM2-binding Bromodomain PF00439.20 EWM23943.1 - 7.4e-22 77.0 0.0 1.5e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 Bromodomain Tet_JBP PF12851.2 EWM23943.1 - 0.014 14.7 0.1 0.24 10.6 0.0 2.4 2 0 0 2 2 2 0 Oxygenase domain of the 2OGFeDO superfamily DivIC PF04977.10 EWM23943.1 - 0.043 13.2 0.6 0.043 13.2 0.4 3.4 2 1 0 2 2 2 0 Septum formation initiator Borrelia_P83 PF05262.6 EWM23943.1 - 1.1 7.4 18.2 13 3.9 0.0 2.3 2 1 0 2 2 2 0 Borrelia P83/100 protein SF3b1 PF08920.5 EWM23944.1 - 1.7e-24 86.5 6.8 2.6e-20 72.9 4.7 3.3 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 EWM23944.1 - 6.7e-16 58.3 9.3 0.00025 21.2 0.0 8.0 5 3 3 8 8 8 6 HEAT repeats HEAT PF02985.17 EWM23944.1 - 7.8e-14 50.4 8.8 0.11 12.6 0.0 9.5 10 0 0 10 10 10 3 HEAT repeat HEAT_EZ PF13513.1 EWM23944.1 - 4e-11 43.0 4.2 0.46 11.0 0.0 8.2 6 2 2 8 8 8 3 HEAT-like repeat Adaptin_N PF01602.15 EWM23944.1 - 1.3e-07 30.3 0.0 0.00028 19.3 0.0 2.6 1 1 0 2 2 2 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 EWM23944.1 - 0.0002 21.6 2.9 0.89 9.9 0.0 5.1 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region Arm PF00514.18 EWM23944.1 - 0.0002 21.0 1.2 8.6 6.3 0.0 5.3 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EWM23944.1 - 0.00027 20.3 3.2 0.072 12.4 0.0 3.1 4 0 0 4 4 4 2 CLASP N terminal TIP120 PF08623.5 EWM23944.1 - 0.0034 16.9 0.0 1.1 8.8 0.0 2.9 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) NUC173 PF08161.7 EWM23944.1 - 0.0056 16.0 1.4 19 4.5 0.0 4.7 5 0 0 5 5 5 0 NUC173 domain DFP PF04127.10 EWM23945.1 - 8e-20 71.2 0.0 4.3e-09 36.2 0.0 3.1 1 1 1 2 2 2 2 DNA / pantothenate metabolism flavoprotein Acyl-CoA_dh_1 PF00441.19 EWM23946.1 - 7e-28 97.6 0.4 7e-28 97.6 0.3 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EWM23946.1 - 8e-27 94.0 0.1 2.2e-26 92.6 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EWM23946.1 - 3.8e-20 71.1 0.0 7.3e-20 70.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EWM23946.1 - 8.8e-08 32.4 0.0 1.4e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EWM23946.1 - 0.08 12.3 0.0 0.64 9.3 0.0 2.0 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal DUF4038 PF13204.1 EWM23947.1 - 0.084 12.1 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) CCT PF06203.9 EWM23952.1 - 5.4e-14 51.5 8.6 8.2e-14 50.9 6.0 1.3 1 0 0 1 1 1 1 CCT motif DUF3460 PF11943.3 EWM23952.1 - 0.21 11.6 0.8 0.41 10.7 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3460) Na_H_Exchanger PF00999.16 EWM23953.1 - 5.9e-53 179.7 38.3 8.3e-53 179.2 26.5 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Aminotran_1_2 PF00155.16 EWM23954.1 - 1.4e-58 198.6 0.0 1.7e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EWM23954.1 - 0.0023 16.5 0.0 0.0039 15.8 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.16 EWM23954.1 - 0.0048 16.0 0.0 0.0075 15.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_3 PF00202.16 EWM23954.1 - 0.013 14.3 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-III Abhydrolase_5 PF12695.2 EWM23954.1 - 0.097 12.4 0.0 0.32 10.7 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Pro_isomerase PF00160.16 EWM23955.1 - 4e-47 160.2 0.0 4.6e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Complex1_LYR PF05347.10 EWM23956.1 - 5.6e-14 51.6 2.7 5.6e-14 51.6 1.9 1.6 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EWM23956.1 - 2.8e-13 49.8 1.7 5.1e-13 49.0 1.1 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Chloroa_b-bind PF00504.16 EWM23957.1 - 3.6e-35 121.5 0.0 4.8e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Dus PF01207.12 EWM23958.1 - 2.1e-66 223.8 0.0 3.4e-66 223.1 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 EWM23958.1 - 6.1e-05 22.1 0.1 0.013 14.5 0.0 2.4 2 1 0 2 2 2 1 Dihydroorotate dehydrogenase IMPDH PF00478.20 EWM23958.1 - 0.0014 17.6 0.0 0.0085 15.0 0.0 2.0 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 EWM23958.1 - 0.014 14.6 0.0 0.03 13.6 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein DUF2102 PF09875.4 EWM23959.1 - 0.045 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) zf-GRF PF06839.7 EWM23960.1 - 4.6e-13 48.8 0.5 1.2e-12 47.5 0.4 1.8 1 0 0 1 1 1 1 GRF zinc finger Helicase_C PF00271.26 EWM23960.1 - 1.8e-11 43.7 0.0 2.1e-10 40.3 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 EWM23960.1 - 7.9e-11 41.7 0.0 1.6e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SAP PF02037.22 EWM23960.1 - 8.1e-06 25.2 0.2 3e-05 23.4 0.2 2.1 1 0 0 1 1 1 1 SAP domain Drc1-Sld2 PF11719.3 EWM23960.1 - 0.0054 15.8 0.1 0.011 14.8 0.1 1.5 1 0 0 1 1 1 1 DNA replication and checkpoint protein ResIII PF04851.10 EWM23960.1 - 0.074 12.8 0.0 1 9.1 0.0 2.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit E1-E2_ATPase PF00122.15 EWM23961.1 - 1.6e-56 190.8 1.4 3.6e-56 189.7 1.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EWM23961.1 - 1.7e-37 128.7 2.8 1.7e-37 128.7 1.9 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EWM23961.1 - 3.7e-32 112.4 0.0 1.5e-26 94.1 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EWM23961.1 - 4.4e-16 58.6 0.0 1.2e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EWM23961.1 - 1.1e-15 56.8 0.4 4.8e-15 54.7 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EWM23961.1 - 2.9e-15 56.9 0.0 1.1e-14 55.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EWM23961.1 - 3.1e-05 23.7 0.8 0.0012 18.5 0.5 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Proteasome PF00227.21 EWM23962.1 - 1.7e-23 82.8 0.0 2.6e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EWM23962.1 - 1.1e-05 24.6 0.0 2.1e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Arginase PF00491.16 EWM23963.1 - 3.6e-69 233.1 0.2 4.3e-69 232.8 0.2 1.0 1 0 0 1 1 1 1 Arginase family Ribosomal_L14e PF01929.12 EWM23964.1 - 1.1e-30 105.8 7.0 1.6e-30 105.2 4.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EWM23964.1 - 0.054 13.2 0.6 0.11 12.2 0.3 1.6 1 1 0 1 1 1 0 KOW motif WD40 PF00400.27 EWM23965.1 - 2.7e-27 93.6 5.1 1.3e-06 28.0 0.4 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Katanin_con80 PF13925.1 EWM23965.1 - 7.1e-12 45.3 0.0 1.3e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 con80 domain of Katanin eIF2A PF08662.6 EWM23965.1 - 0.064 12.9 0.0 1.7 8.3 0.0 2.3 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A DSS1_SEM1 PF05160.8 EWM23966.1 - 1.8e-15 56.4 23.4 2.5e-15 55.9 16.2 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family DUF2947 PF11163.3 EWM23966.1 - 0.013 15.0 3.5 0.016 14.8 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) DSS1_SEM1 PF05160.8 EWM23967.1 - 4e-05 23.2 7.6 6.1e-05 22.7 5.3 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family PWWP PF00855.12 EWM23968.1 - 1.9e-15 56.8 0.1 5.5e-15 55.3 0.1 1.8 1 0 0 1 1 1 1 PWWP domain zf-HC5HC2H PF13771.1 EWM23968.1 - 0.00043 20.3 4.7 0.00043 20.3 3.3 3.0 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EWM23968.1 - 0.021 14.8 0.4 0.021 14.8 0.3 3.1 3 0 0 3 3 3 0 PHD-zinc-finger like domain PHD PF00628.24 EWM23968.1 - 0.058 13.0 0.3 0.058 13.0 0.2 3.8 5 0 0 5 5 5 0 PHD-finger DEAD PF00270.24 EWM23969.1 - 0.0014 18.1 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase GSHPx PF00255.14 EWM23970.1 - 5.6e-35 118.9 0.0 1.2e-34 117.8 0.0 1.5 2 0 0 2 2 2 1 Glutathione peroxidase AhpC-TSA PF00578.16 EWM23970.1 - 4.3e-08 32.8 0.0 6.3e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EWM23970.1 - 0.00021 20.8 0.0 0.00033 20.2 0.0 1.3 1 0 0 1 1 1 1 Redoxin HhH-GPD PF00730.20 EWM23972.1 - 1.2e-18 67.3 0.0 2.2e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EWM23972.1 - 6e-09 35.1 0.0 2e-08 33.4 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 EWM23972.1 - 0.017 15.2 0.0 0.057 13.5 0.0 1.8 2 0 0 2 2 2 0 Helix-hairpin-helix domain EndIII_4Fe-2S PF10576.4 EWM23972.1 - 0.54 10.5 6.0 1.5 9.1 4.2 1.8 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Cpn60_TCP1 PF00118.19 EWM23973.1 - 9.8e-148 492.7 0.7 1.1e-147 492.5 0.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DAP_B PF07930.7 EWM23973.1 - 0.046 13.4 0.1 0.21 11.3 0.1 2.2 1 1 0 1 1 1 0 D-aminopeptidase, domain B DUF221 PF02714.10 EWM23974.1 - 2.9e-12 46.0 7.6 3.5e-05 22.8 0.0 3.1 2 1 0 2 2 2 2 Domain of unknown function DUF221 KIAA1430 PF13879.1 EWM23974.1 - 0.025 14.9 2.0 3.9 7.9 0.2 2.4 2 0 0 2 2 2 0 KIAA1430 homologue RRM_6 PF14259.1 EWM23974.1 - 0.1 12.6 0.1 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FA_desaturase PF00487.19 EWM23975.1 - 1.1e-14 54.5 22.9 1.1e-14 54.5 15.9 1.4 2 0 0 2 2 2 1 Fatty acid desaturase COX6B PF02297.12 EWM23976.1 - 1.2e-10 41.2 4.7 1.6e-10 40.8 3.2 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb SpoU_methylase PF00588.14 EWM23976.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.3 1 1 0 1 1 1 0 SpoU rRNA Methylase family DUF749 PF05370.6 EWM23976.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF749) tRNA-synt_2b PF00587.20 EWM23977.1 - 2.8e-41 140.9 0.0 5.1e-41 140.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EWM23977.1 - 1.7e-20 72.7 0.1 3.6e-20 71.7 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 EWM23977.1 - 3.2e-09 36.5 0.0 6.1e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 EWM23977.1 - 1.7e-08 34.2 0.0 2.4e-07 30.4 0.0 2.7 2 1 0 2 2 2 1 TGS domain AA_permease_2 PF13520.1 EWM23978.1 - 2.4e-34 118.6 29.7 2.4e-34 118.6 20.6 1.5 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EWM23978.1 - 9.7e-25 86.8 29.2 9.7e-25 86.8 20.3 1.5 1 1 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.1 EWM23978.1 - 7.6e-10 38.5 3.5 7.6e-10 38.5 2.4 3.7 4 1 1 5 5 5 1 C-terminus of AA_permease UPF0081 PF03652.10 EWM23982.1 - 4.2e-22 78.7 0.0 6.4e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0081) UPF0081 PF03652.10 EWM23983.1 - 4.2e-22 78.7 0.0 6.4e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0081) ORC6 PF05460.8 EWM23984.1 - 0.1 11.6 11.8 0.71 8.9 8.1 1.9 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) AKAP7_RIRII_bdg PF10470.4 EWM23985.1 - 0.042 13.6 0.7 0.088 12.6 0.5 1.5 1 0 0 1 1 1 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein AAA_30 PF13604.1 EWM23986.1 - 4.1e-39 134.1 1.4 1e-38 132.9 1.0 1.7 1 0 0 1 1 1 1 AAA domain HHH_4 PF14490.1 EWM23986.1 - 2e-34 117.1 0.0 1.8e-28 98.1 0.0 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix containing domain UvrD_C_2 PF13538.1 EWM23986.1 - 2.7e-22 78.8 0.0 5.5e-22 77.8 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EWM23986.1 - 9.8e-16 57.2 5.1 9.8e-16 57.2 3.6 2.7 3 0 0 3 3 2 1 Part of AAA domain Viral_helicase1 PF01443.13 EWM23986.1 - 2.4e-11 43.6 0.0 7.1e-05 22.4 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 EWM23986.1 - 6.1e-10 39.0 1.2 1.4e-05 24.7 0.3 2.4 1 1 1 2 2 2 2 AAA domain HHH_5 PF14520.1 EWM23986.1 - 1.2e-09 38.2 1.5 5.8e-08 32.8 0.0 3.4 4 0 0 4 4 3 1 Helix-hairpin-helix domain PIF1 PF05970.9 EWM23986.1 - 6.8e-08 31.8 0.0 2.4e-07 30.0 0.0 1.8 1 1 0 1 1 1 1 PIF1-like helicase Helicase_RecD PF05127.9 EWM23986.1 - 9.9e-08 31.8 0.1 2.3e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Helicase AAA_28 PF13521.1 EWM23986.1 - 9.5e-05 22.4 0.1 0.00039 20.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EWM23986.1 - 0.00019 21.5 0.1 0.00074 19.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EWM23986.1 - 0.00063 18.8 0.1 0.0017 17.4 0.0 1.8 2 0 0 2 2 1 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 EWM23986.1 - 0.0018 17.7 0.0 0.0045 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 EWM23986.1 - 0.0025 17.1 1.0 2 7.5 0.0 2.3 1 1 1 2 2 2 2 PhoH-like protein AAA_16 PF13191.1 EWM23986.1 - 0.0025 17.8 0.2 0.099 12.6 0.0 3.0 3 0 0 3 3 2 1 AAA ATPase domain HHH_2 PF12826.2 EWM23986.1 - 0.0034 17.2 0.0 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif AAA PF00004.24 EWM23986.1 - 0.007 16.5 0.0 0.023 14.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EWM23986.1 - 0.012 15.3 0.3 0.049 13.3 0.1 2.2 2 0 0 2 2 1 0 NTPase KaiC PF06745.8 EWM23986.1 - 0.02 14.0 0.1 0.049 12.7 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.1 EWM23986.1 - 0.028 13.9 0.0 0.068 12.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ArgK PF03308.11 EWM23986.1 - 0.04 12.7 0.1 0.07 11.8 0.0 1.4 1 0 0 1 1 1 0 ArgK protein T2SE PF00437.15 EWM23986.1 - 0.047 12.5 0.0 0.083 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.22 EWM23986.1 - 0.065 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter TIP49 PF06068.8 EWM23986.1 - 0.073 11.7 0.9 0.52 8.9 0.1 2.1 2 0 0 2 2 2 0 TIP49 C-terminus CbiA PF01656.18 EWM23986.1 - 0.092 12.1 0.1 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_5 PF07728.9 EWM23986.1 - 0.1 12.3 0.1 0.44 10.2 0.1 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EWM23986.1 - 0.11 11.9 1.5 0.85 9.0 0.9 2.4 1 1 1 2 2 2 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 EWM23986.1 - 0.12 11.4 0.1 0.24 10.4 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin KTI12 PF08433.5 EWM23986.1 - 0.13 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Mtc PF03820.12 EWM23988.1 - 1.8e-74 250.2 0.0 2e-74 250.0 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Methyltransf_26 PF13659.1 EWM23989.1 - 2.7e-11 43.5 0.0 6.1e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EWM23989.1 - 5.3e-11 42.4 0.1 7e-10 38.7 0.0 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.13 EWM23989.1 - 1.9e-05 24.3 0.0 0.21 11.0 0.0 2.4 2 0 0 2 2 2 2 DNA methylase N6_Mtase PF02384.11 EWM23989.1 - 0.0042 16.2 0.0 0.0088 15.1 0.0 1.4 1 1 0 1 1 1 1 N-6 DNA Methylase MethyltransfD12 PF02086.10 EWM23989.1 - 0.045 13.2 0.1 1.8 7.9 0.0 2.4 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase Dynamitin PF04912.9 EWM23990.1 - 9e-33 113.6 0.0 6.9e-32 110.7 0.0 2.0 1 1 0 1 1 1 1 Dynamitin MRP-S26 PF14943.1 EWM23991.1 - 1.1e-05 25.1 20.2 1.9e-05 24.3 12.1 2.0 2 0 0 2 2 2 1 Mitochondrial ribosome subunit S26 SRP14 PF02290.10 EWM23991.1 - 0.0087 15.9 2.1 0.021 14.7 1.4 1.6 1 0 0 1 1 1 1 Signal recognition particle 14kD protein Sec7 PF01369.15 EWM23991.1 - 0.096 12.3 2.1 0.18 11.4 1.4 1.4 1 0 0 1 1 1 0 Sec7 domain Phosphoprotein PF00922.12 EWM23991.1 - 0.12 11.5 4.4 6.7 5.8 3.1 2.2 1 1 0 1 1 1 0 Vesiculovirus phosphoprotein UPF0242 PF06785.6 EWM23991.1 - 0.17 10.5 10.4 0.28 9.7 7.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) PhaP_Bmeg PF09602.5 EWM23991.1 - 1.3 8.8 11.9 3.5 7.4 8.2 1.8 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) hDGE_amylase PF14701.1 EWM23991.1 - 3.7 6.3 7.6 21 3.8 4.9 1.9 2 0 0 2 2 2 0 glucanotransferase domain of human glycogen debranching enzyme RNase_T PF00929.19 EWM23992.1 - 1.7e-16 60.9 0.0 3.7e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 Exonuclease Nicastrin PF05450.10 EWM23993.1 - 1.3e-18 67.0 0.0 4.8e-09 35.7 0.0 2.2 2 0 0 2 2 2 2 Nicastrin Peptidase_M28 PF04389.12 EWM23993.1 - 0.00092 18.9 0.0 0.0037 17.0 0.0 2.0 1 1 0 1 1 1 1 Peptidase family M28 Glyoxalase_4 PF13669.1 EWM23995.1 - 3.2e-17 62.5 0.0 4.7e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EWM23995.1 - 0.033 14.1 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase-like domain WW PF00397.21 EWM23996.1 - 0.00076 19.2 9.8 0.0016 18.2 6.8 1.6 1 0 0 1 1 1 1 WW domain PfkB PF00294.19 EWM23996.1 - 0.02 14.0 0.0 0.099 11.7 0.0 1.9 2 0 0 2 2 2 0 pfkB family carbohydrate kinase WD40 PF00400.27 EWM23997.1 - 7.4e-11 41.4 0.0 2.2e-05 24.1 0.0 2.8 2 1 0 2 2 2 2 WD domain, G-beta repeat Metallophos PF00149.23 EWM23998.1 - 2.5e-05 23.7 0.1 7.6e-05 22.1 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EWM23998.1 - 0.00034 20.4 0.0 0.00072 19.4 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Peptidase_C12 PF01088.16 EWM23999.1 - 7.2e-63 211.6 0.0 8.8e-63 211.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 RRM_1 PF00076.17 EWM24001.1 - 4.1e-21 74.3 0.0 5.9e-21 73.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM24001.1 - 1.6e-16 60.0 0.0 2.6e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM24001.1 - 0.00015 21.5 0.0 0.00024 20.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CH PF00307.26 EWM24002.1 - 1.2e-16 60.6 0.0 1.7e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EWM24002.1 - 0.00025 20.6 0.0 0.00039 19.9 0.0 1.3 1 0 0 1 1 1 1 CAMSAP CH domain CDC24 PF06395.6 EWM24002.1 - 0.00035 20.5 0.1 0.00058 19.8 0.0 1.3 1 0 0 1 1 1 1 CDC24 Calponin GMC_oxred_N PF00732.14 EWM24003.1 - 1.9e-30 106.0 0.0 2.6e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EWM24003.1 - 2.1e-27 96.2 0.1 3.4e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DEC-1_N PF04625.8 EWM24003.1 - 0.0096 14.6 0.0 0.014 14.0 0.0 1.1 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region SP2 PF03014.9 EWM24003.1 - 0.01 13.7 0.1 0.014 13.3 0.1 1.1 1 0 0 1 1 1 0 Structural protein 2 NIR_SIR PF01077.17 EWM24004.1 - 1.2e-47 161.1 0.0 4e-37 126.9 0.0 2.3 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 EWM24004.1 - 3.7e-28 96.9 0.0 1.1e-14 53.8 0.0 2.8 3 0 0 3 3 3 2 Nitrite/Sulfite reductase ferredoxin-like half domain DUF647 PF04884.9 EWM24005.1 - 3.1e-62 210.0 0.9 4.9e-62 209.3 0.7 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DUF1084 PF06454.6 EWM24006.1 - 2.7e-12 46.3 14.6 3.3e-11 42.7 10.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) IBN_N PF03810.14 EWM24007.1 - 2.7e-09 36.8 1.4 8.8e-09 35.1 1.0 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Methyltransf_16 PF10294.4 EWM24008.1 - 9.7e-10 38.1 0.0 1.8e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EWM24008.1 - 0.082 12.6 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Rieske PF00355.21 EWM24009.1 - 4.6e-16 58.1 0.0 6.9e-16 57.5 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 EWM24009.1 - 3.6e-13 49.1 0.0 7e-13 48.1 0.0 1.4 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Auto_anti-p27 PF06677.7 EWM24009.1 - 0.0035 17.0 0.1 0.38 10.5 0.0 2.5 1 1 1 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) PsbW PF07123.7 EWM24011.1 - 0.055 13.5 0.6 0.18 11.8 0.1 2.1 1 1 1 2 2 2 0 Photosystem II reaction centre W protein (PsbW) MRG PF05712.8 EWM24012.1 - 2.6e-43 147.1 0.0 4.1e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 EWM24012.1 - 1.6e-10 40.5 0.1 3.5e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 EWM24012.1 - 0.023 14.3 0.4 0.049 13.3 0.3 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain HIG_1_N PF04588.8 EWM24013.1 - 0.0012 18.5 1.2 0.0026 17.4 0.0 2.0 2 0 0 2 2 2 1 Hypoxia induced protein conserved region ENOD93 PF03386.9 EWM24013.1 - 0.057 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Early nodulin 93 ENOD93 protein HEM4 PF02602.10 EWM24015.1 - 7.6e-32 110.4 0.6 5.1e-31 107.7 0.4 1.9 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD AAA_2 PF07724.9 EWM24016.1 - 1.1e-53 181.6 2.8 1.4e-48 165.0 0.0 3.5 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EWM24016.1 - 5.7e-26 90.2 0.1 5.7e-26 90.2 0.0 2.8 3 0 0 3 3 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EWM24016.1 - 3.4e-25 88.7 3.7 2.6e-14 53.5 0.0 3.6 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) Clp_N PF02861.15 EWM24016.1 - 6.3e-19 67.6 0.5 2.7e-13 49.6 0.1 3.2 2 0 0 2 2 2 2 Clp amino terminal domain AAA_5 PF07728.9 EWM24016.1 - 1.9e-15 56.8 0.7 1.8e-09 37.4 0.0 4.0 3 1 1 4 4 4 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EWM24016.1 - 1e-12 48.4 0.0 0.0007 19.6 0.0 4.7 3 1 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 EWM24016.1 - 8.8e-10 38.8 1.2 0.0062 16.6 0.0 4.3 2 2 1 3 3 3 2 AAA domain Sigma54_activat PF00158.21 EWM24016.1 - 1.4e-08 34.3 0.0 5.8e-05 22.6 0.0 2.7 2 1 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.12 EWM24016.1 - 6.8e-08 32.1 0.0 0.0073 15.7 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 EWM24016.1 - 5.4e-07 29.5 0.0 0.026 14.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EWM24016.1 - 1.5e-06 28.5 2.6 0.042 14.1 0.0 4.1 4 0 0 4 4 3 2 AAA domain AAA_17 PF13207.1 EWM24016.1 - 1.8e-06 28.7 1.0 0.16 12.8 0.0 3.8 3 1 1 4 4 3 2 AAA domain Mg_chelatase PF01078.16 EWM24016.1 - 1.8e-05 24.0 0.1 0.042 13.0 0.1 3.3 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EWM24016.1 - 4e-05 23.3 0.1 0.25 10.9 0.0 3.4 3 0 0 3 3 3 2 NACHT domain Arch_ATPase PF01637.13 EWM24016.1 - 8.4e-05 22.3 1.1 0.66 9.6 0.1 4.4 3 1 1 4 4 4 1 Archaeal ATPase Zeta_toxin PF06414.7 EWM24016.1 - 0.00015 20.9 0.2 0.027 13.5 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin RNA_helicase PF00910.17 EWM24016.1 - 0.00026 21.1 0.4 0.89 9.7 0.0 3.3 3 0 0 3 3 2 2 RNA helicase AAA_25 PF13481.1 EWM24016.1 - 0.00031 20.1 0.0 0.64 9.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EWM24016.1 - 0.00048 19.8 0.1 0.39 10.5 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain ABC_tran PF00005.22 EWM24016.1 - 0.0018 18.5 0.3 0.26 11.5 0.0 3.4 3 0 0 3 3 3 1 ABC transporter ResIII PF04851.10 EWM24016.1 - 0.003 17.4 0.9 0.49 10.1 0.0 3.5 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit Torsin PF06309.6 EWM24016.1 - 0.0045 16.8 0.0 0.03 14.2 0.0 2.2 2 0 0 2 2 2 1 Torsin AAA_28 PF13521.1 EWM24016.1 - 0.0052 16.7 2.1 4.9 7.0 0.0 3.9 3 1 1 4 4 4 1 AAA domain AAA_33 PF13671.1 EWM24016.1 - 0.0092 15.8 0.3 3.2 7.6 0.0 3.5 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.1 EWM24016.1 - 0.012 15.2 0.0 2.5 7.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EWM24016.1 - 0.012 15.0 0.7 0.56 9.5 0.0 3.0 2 1 0 2 2 2 0 AAA-like domain DUF258 PF03193.11 EWM24016.1 - 0.014 14.6 0.0 2.2 7.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_3 PF07726.6 EWM24016.1 - 0.058 13.0 0.2 13 5.3 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.17 EWM24016.1 - 0.087 12.2 2.8 0.9 8.9 0.0 3.1 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain DUF848 PF05852.6 EWM24016.1 - 1.4 8.7 9.1 0.52 10.1 3.5 2.4 2 1 0 2 2 1 0 Gammaherpesvirus protein of unknown function (DUF848) Telomere_reg-2 PF10193.4 EWM24017.1 - 1.1e-18 67.5 0.0 3.1e-17 62.8 0.0 2.3 2 0 0 2 2 2 1 Telomere length regulation protein Abhydrolase_6 PF12697.2 EWM24018.1 - 7.2e-24 84.9 5.7 7.2e-24 84.9 4.0 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM24018.1 - 1.4e-19 70.3 0.3 4.1e-19 68.7 0.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EWM24018.1 - 1.8e-06 27.6 0.6 3.9e-06 26.5 0.4 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EWM24018.1 - 6.5e-05 22.4 0.0 0.02 14.3 0.0 2.7 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 EWM24018.1 - 0.0002 20.9 0.0 0.0072 15.9 0.0 2.8 3 0 0 3 3 3 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EWM24018.1 - 0.0019 18.4 0.1 0.0048 17.1 0.1 1.7 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 EWM24018.1 - 0.0058 16.4 0.3 0.032 14.0 0.0 2.3 3 0 0 3 3 3 1 Putative lysophospholipase DUF818 PF05677.7 EWM24018.1 - 0.013 14.3 0.0 0.019 13.7 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) DLH PF01738.13 EWM24018.1 - 0.019 14.2 0.0 0.83 8.8 0.0 2.5 3 0 0 3 3 3 0 Dienelactone hydrolase family Peptidase_S15 PF02129.13 EWM24018.1 - 0.061 12.7 0.0 0.16 11.3 0.0 1.7 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydro_lipase PF04083.11 EWM24018.1 - 0.079 12.3 0.0 0.24 10.7 0.0 1.8 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region RNase_HII PF01351.13 EWM24019.1 - 1.3e-44 152.2 0.0 1.8e-44 151.8 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII Tcp10_C PF07202.8 EWM24020.1 - 3.4e-19 69.0 0.0 5.6e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 T-complex protein 10 C-terminus Nucleoplasmin PF03066.10 EWM24020.1 - 0.014 14.8 7.7 0.039 13.4 5.3 1.7 1 0 0 1 1 1 0 Nucleoplasmin SLIDE PF09111.5 EWM24021.1 - 1.9e-31 108.2 0.6 1.9e-31 108.2 0.4 2.0 2 0 0 2 2 2 1 SLIDE HMG_box PF00505.14 EWM24021.1 - 9.8e-08 32.1 1.4 9.8e-08 32.1 1.0 2.5 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EWM24021.1 - 1.6e-05 25.1 1.2 7.8e-05 22.9 0.8 2.3 1 0 0 1 1 1 1 HMG-box domain Myb_DNA-binding PF00249.26 EWM24021.1 - 0.022 14.8 0.0 15 5.7 0.0 3.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain DUF3349 PF11829.3 EWM24021.1 - 0.032 14.6 0.1 2.6 8.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) Apolipoprotein PF01442.13 EWM24022.1 - 0.004 16.7 25.3 0.004 16.7 17.6 2.1 1 1 1 2 2 2 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 EWM24022.1 - 0.011 16.0 36.7 0.069 13.5 2.7 4.3 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 EWM24022.1 - 1.3 9.4 42.1 1.5e+04 -20.6 29.2 5.1 1 1 0 1 1 1 0 YtxH-like protein Tet_JBP PF12851.2 EWM24022.1 - 2.6 7.2 5.8 1.1 8.4 0.7 2.3 1 1 1 2 2 2 0 Oxygenase domain of the 2OGFeDO superfamily YqzH PF14164.1 EWM24022.1 - 5.4 7.0 7.8 17 5.3 0.2 3.2 3 0 0 3 3 3 0 YqzH-like protein Phtf-FEM1B_bdg PF12129.3 EWM24024.1 - 4.5e-06 26.0 0.0 6.7e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Male germ-cell putative homeodomain transcription factor Nop14 PF04147.7 EWM24024.1 - 1.3e-05 23.4 16.9 1.6e-05 23.0 11.7 1.1 1 0 0 1 1 1 1 Nop14-like family Ycf1 PF05758.7 EWM24024.1 - 2.9 5.4 9.2 3.8 5.1 6.4 1.2 1 0 0 1 1 1 0 Ycf1 DUF605 PF04652.11 EWM24024.1 - 5.4 6.3 14.9 9.4 5.5 10.3 1.3 1 0 0 1 1 1 0 Vta1 like Cluap1 PF10234.4 EWM24025.1 - 6.1e-19 68.2 8.3 9.3e-19 67.6 5.7 1.2 1 0 0 1 1 1 1 Clusterin-associated protein-1 Cep57_CLD_2 PF14197.1 EWM24025.1 - 0.0023 17.8 7.5 0.0023 17.8 5.2 3.0 2 1 1 3 3 3 1 Centrosome localisation domain of PPC89 APG6 PF04111.7 EWM24025.1 - 0.095 11.7 9.4 0.14 11.2 6.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EWM24025.1 - 0.3 10.6 17.4 0.03 13.9 8.9 1.6 1 1 1 2 2 2 0 IncA protein GAS PF13851.1 EWM24025.1 - 0.33 10.1 9.9 0.67 9.1 6.9 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ERM PF00769.14 EWM24025.1 - 0.38 10.2 17.1 0.62 9.5 11.8 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF1978 PF09321.5 EWM24025.1 - 0.63 9.4 10.5 1.2 8.4 7.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1978) ADIP PF11559.3 EWM24025.1 - 0.87 9.4 13.9 4.8 7.0 2.7 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FUSC PF04632.7 EWM24025.1 - 1 7.6 7.4 1.3 7.4 5.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DivIC PF04977.10 EWM24025.1 - 1.3 8.5 12.2 0.58 9.6 2.1 2.5 1 1 1 2 2 2 0 Septum formation initiator Occludin_ELL PF07303.8 EWM24025.1 - 9.7 6.9 8.9 3.2 8.5 2.5 2.2 1 1 1 2 2 2 0 Occludin homology domain UcrQ PF02939.11 EWM24028.1 - 1.3e-10 40.9 0.1 1.7e-10 40.5 0.1 1.1 1 0 0 1 1 1 1 UcrQ family DUF2741 PF10890.3 EWM24028.1 - 0.0059 16.7 0.0 0.0084 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2741) Patatin PF01734.17 EWM24029.1 - 1.2e-08 35.1 10.9 6.7e-08 32.6 6.4 2.7 2 1 0 2 2 2 1 Patatin-like phospholipase TIP49 PF06068.8 EWM24030.1 - 1.2e-178 593.9 1.8 1.4e-178 593.6 1.3 1.1 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EWM24030.1 - 6e-10 39.4 2.1 2.2e-06 27.9 0.1 3.4 3 1 1 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EWM24030.1 - 6.8e-07 29.1 0.2 0.00021 21.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EWM24030.1 - 1.2e-06 28.7 0.5 0.028 14.5 0.1 2.7 1 1 0 2 2 2 2 AAA domain DnaB_C PF03796.10 EWM24030.1 - 3.1e-06 26.2 0.1 5e-06 25.5 0.1 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain RuvB_N PF05496.7 EWM24030.1 - 5.4e-06 25.6 0.1 0.0017 17.4 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EWM24030.1 - 5.5e-06 25.9 0.1 1.5e-05 24.5 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EWM24030.1 - 7.5e-05 22.7 0.1 0.0028 17.6 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.16 EWM24030.1 - 0.00032 19.9 1.0 0.0088 15.2 0.3 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EWM24030.1 - 0.00069 18.7 0.9 0.0016 17.5 0.6 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 EWM24030.1 - 0.00098 18.8 0.1 0.0032 17.2 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain Imm41 PF15583.1 EWM24030.1 - 0.0015 18.3 0.9 0.0092 15.7 0.2 2.2 2 0 0 2 2 2 1 Immunity protein 41 NACHT PF05729.7 EWM24030.1 - 0.0015 18.2 0.0 0.0029 17.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Sigma54_activat PF00158.21 EWM24030.1 - 0.0019 17.6 0.1 0.93 8.9 0.1 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.1 EWM24030.1 - 0.0026 18.0 0.1 0.015 15.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 EWM24030.1 - 0.0048 16.0 0.2 0.0081 15.2 0.1 1.5 1 0 0 1 1 1 1 KaiC AAA_28 PF13521.1 EWM24030.1 - 0.0069 16.3 0.2 0.017 15.0 0.1 1.7 1 0 0 1 1 1 1 AAA domain Zot PF05707.7 EWM24030.1 - 0.01 15.2 0.1 0.33 10.4 0.0 2.4 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) UPF0079 PF02367.12 EWM24030.1 - 0.011 15.3 0.3 0.034 13.7 0.2 1.8 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 EWM24030.1 - 0.022 15.5 0.0 0.068 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EWM24030.1 - 0.035 13.6 0.0 0.065 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 EWM24030.1 - 0.054 12.7 0.0 0.098 11.8 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.1 EWM24030.1 - 0.058 13.2 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EWM24030.1 - 0.063 12.2 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 EWM24030.1 - 0.12 11.7 0.6 0.25 10.7 0.4 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Sipho_tail PF05709.6 EWM24030.1 - 0.17 11.0 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Phage tail protein CK_II_beta PF01214.13 EWM24032.1 - 1.6e-72 242.8 0.0 1.6e-72 242.8 0.0 1.7 2 0 0 2 2 1 1 Casein kinase II regulatory subunit Spore_coat_CotO PF14153.1 EWM24032.1 - 0.0016 17.9 6.5 0.0034 16.8 4.5 1.5 1 0 0 1 1 1 1 Spore coat protein CotO Nop14 PF04147.7 EWM24032.1 - 0.016 13.1 19.9 0.026 12.4 13.8 1.3 1 0 0 1 1 1 0 Nop14-like family BTV_NS2 PF04514.7 EWM24032.1 - 0.14 11.0 7.2 0.23 10.2 5.0 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Ycf1 PF05758.7 EWM24032.1 - 0.16 9.6 4.6 0.2 9.3 3.2 1.1 1 0 0 1 1 1 0 Ycf1 Vfa1 PF08432.5 EWM24032.1 - 1 9.3 9.9 2.3 8.1 6.9 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SDA1 PF05285.7 EWM24032.1 - 1.2 8.3 19.5 2.2 7.4 13.5 1.4 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 EWM24032.1 - 2.8 6.2 32.6 0.96 7.8 18.0 2.1 2 0 0 2 2 2 0 Daxx Family Tim54 PF11711.3 EWM24032.1 - 2.9 6.4 10.6 5.2 5.5 7.4 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Rhabdo_ncap PF00945.13 EWM24032.1 - 3.1 6.2 12.0 5.6 5.4 8.3 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein RRN3 PF05327.6 EWM24032.1 - 5.9 4.8 9.8 8.2 4.3 6.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 APG6 PF04111.7 EWM24032.1 - 6 5.8 10.9 9.3 5.1 7.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 BUD22 PF09073.5 EWM24032.1 - 7.2 5.5 21.1 0.047 12.7 8.2 2.0 2 0 0 2 2 2 0 BUD22 BT1 PF03092.11 EWM24033.1 - 2.6e-54 184.6 14.8 3.2e-54 184.2 10.3 1.1 1 0 0 1 1 1 1 BT1 family MFS_1 PF07690.11 EWM24033.1 - 3.6e-10 39.0 35.8 3.6e-10 39.0 24.8 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily NHL PF01436.16 EWM24034.1 - 4.7e-24 83.0 3.0 0.00017 21.3 0.0 6.6 6 0 0 6 6 6 5 NHL repeat Thioredoxin_8 PF13905.1 EWM24034.1 - 1.3e-11 44.4 0.0 2.4e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EWM24034.1 - 2.3e-08 33.7 0.0 4.6e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EWM24034.1 - 3.7e-07 29.7 0.0 1.2e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 Redoxin SGL PF08450.7 EWM24034.1 - 6.8e-05 22.3 0.0 0.074 12.4 0.0 3.1 2 1 0 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region Thioredoxin_2 PF13098.1 EWM24034.1 - 0.00015 21.9 0.0 0.00026 21.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.15 EWM24034.1 - 0.0033 17.0 0.0 0.0083 15.7 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin GYF PF02213.11 EWM24035.1 - 3.7e-09 36.0 0.0 1.4e-08 34.1 0.0 2.0 2 0 0 2 2 2 1 GYF domain PQQ PF01011.16 EWM24035.1 - 0.08 12.5 0.8 1.3 8.7 0.1 2.4 2 0 0 2 2 2 0 PQQ enzyme repeat SNF2_N PF00176.18 EWM24038.1 - 4.1e-81 272.0 0.2 4.1e-81 272.0 0.1 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EWM24038.1 - 6.9e-16 57.8 0.0 2.1e-15 56.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EWM24038.1 - 2.9e-11 42.7 0.0 7.3e-11 41.4 0.0 1.5 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 HMG_box_2 PF09011.5 EWM24038.1 - 4.9e-11 42.8 0.2 1.5e-10 41.2 0.1 1.9 1 0 0 1 1 1 1 HMG-box domain ResIII PF04851.10 EWM24038.1 - 1.1e-09 38.4 0.1 1.9e-08 34.3 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EWM24038.1 - 9.2e-08 31.7 0.0 7e-07 28.8 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase HMG_box PF00505.14 EWM24038.1 - 5.3e-07 29.8 0.0 1.5e-06 28.3 0.0 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box AAA_14 PF13173.1 EWM24038.1 - 0.0082 16.0 0.1 7.5 6.4 0.0 2.8 3 0 0 3 3 3 2 AAA domain MobB PF03205.9 EWM24038.1 - 0.011 15.4 0.4 1.6 8.4 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EWM24038.1 - 0.066 13.3 0.1 0.47 10.5 0.0 2.5 2 2 0 2 2 2 0 AAA domain DUF4407 PF14362.1 EWM24038.1 - 2.2 7.1 12.8 3.9 6.3 8.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PolyA_pol PF01743.15 EWM24040.1 - 1.4e-26 93.2 0.0 2e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Poly A polymerase head domain HEAT PF02985.17 EWM24041.1 - 6.9e-05 22.6 3.6 0.67 10.1 0.1 4.0 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 EWM24041.1 - 0.00041 20.5 1.7 0.12 12.7 0.1 2.8 1 1 0 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 EWM24041.1 - 0.017 15.5 0.4 1.2 9.7 0.3 2.6 2 0 0 2 2 2 0 HEAT-like repeat Pkinase PF00069.20 EWM24042.1 - 2.3e-40 138.3 0.0 3.1e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM24042.1 - 2.5e-19 69.3 0.0 3.4e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EWM24042.1 - 0.027 14.2 0.5 0.52 10.0 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family F-box-like PF12937.2 EWM24043.1 - 3.3e-07 29.9 0.4 8e-07 28.6 0.2 1.7 1 0 0 1 1 1 1 F-box-like ZZ PF00569.12 EWM24043.1 - 3.9e-07 29.5 12.2 8.7e-07 28.3 8.5 1.6 1 0 0 1 1 1 1 Zinc finger, ZZ type F-box PF00646.28 EWM24043.1 - 2.2e-06 27.1 0.5 4e-06 26.3 0.3 1.4 1 0 0 1 1 1 1 F-box domain USP7_ICP0_bdg PF12436.3 EWM24043.1 - 0.071 12.3 0.0 2.1 7.4 0.0 2.3 2 0 0 2 2 2 0 ICP0-binding domain of Ubiquitin-specific protease 7 DIOX_N PF14226.1 EWM24044.1 - 5.6e-05 23.6 0.0 0.00012 22.5 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EWM24044.1 - 0.00011 22.4 0.0 0.0003 21.0 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3353 PF11833.3 EWM24045.1 - 0.021 14.3 1.7 0.035 13.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) TM2 PF05154.11 EWM24045.1 - 1.2 9.4 5.3 0.18 12.0 0.3 2.1 2 0 0 2 2 2 0 TM2 domain Glyco_hydro_16 PF00722.16 EWM24047.1 - 7.3e-08 31.9 0.0 1.5e-07 30.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Tubulin PF00091.20 EWM24048.1 - 3.5e-62 210.0 0.0 5.8e-62 209.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EWM24048.1 - 9.9e-13 48.2 0.0 6e-12 45.7 0.0 2.1 1 1 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EWM24048.1 - 0.0041 17.1 0.0 0.0082 16.1 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain GIY-YIG PF01541.19 EWM24050.1 - 0.15 12.4 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 GIY-YIG catalytic domain FAT PF02259.18 EWM24051.1 - 2.9e-68 230.4 0.0 1.3e-66 225.0 0.0 3.3 1 1 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 EWM24051.1 - 2.4e-59 200.6 0.3 4e-59 199.9 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 EWM24051.1 - 5.1e-39 133.7 0.0 9.9e-22 77.5 0.0 3.6 3 0 0 3 3 3 2 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 EWM24051.1 - 1.1e-32 112.0 0.8 6.6e-27 93.5 0.1 2.9 2 0 0 2 2 2 2 Rapamycin binding domain FATC PF02260.15 EWM24051.1 - 1.5e-13 49.9 0.0 3.4e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.1 EWM24051.1 - 8.4e-09 35.5 14.2 0.2 11.9 0.2 7.1 6 1 1 7 7 7 4 HEAT repeats HEAT_EZ PF13513.1 EWM24051.1 - 0.0014 19.0 33.7 0.0081 16.6 0.3 9.6 10 1 1 11 11 9 2 HEAT-like repeat HEAT PF02985.17 EWM24051.1 - 0.002 18.0 11.5 0.37 11.0 0.0 6.1 6 0 0 6 6 6 2 HEAT repeat TPR_7 PF13176.1 EWM24051.1 - 0.25 11.2 3.7 2 8.4 0.1 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF3150 PF11348.3 EWM24051.1 - 0.25 10.4 0.0 0.56 9.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) MMS19_C PF12460.3 EWM24051.1 - 2.5 6.7 1.7 40 2.7 0.3 2.8 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal zf-AN1 PF01428.11 EWM24053.1 - 3.5e-16 58.7 33.4 8e-09 35.2 2.7 3.7 3 1 1 4 4 4 2 AN1-like Zinc finger zf-Di19 PF05605.7 EWM24053.1 - 0.00017 21.6 0.7 0.00017 21.6 0.5 3.5 3 1 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding Sporozoite_P67 PF05642.6 EWM24053.1 - 4 5.1 12.2 5.2 4.7 8.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3246 PF11596.3 EWM24054.1 - 0.018 14.3 0.6 0.032 13.5 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Acetyltransf_1 PF00583.19 EWM24055.1 - 0.0024 17.8 0.2 0.062 13.3 0.1 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family CDV3 PF15359.1 EWM24055.1 - 0.029 14.4 0.2 0.059 13.4 0.1 1.5 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 DUF2973 PF11189.3 EWM24056.1 - 0.039 13.7 0.0 2.5 7.9 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) DEAD PF00270.24 EWM24057.1 - 1.4e-44 151.5 0.0 3.2e-44 150.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EWM24057.1 - 4.6e-22 77.6 0.0 1e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EWM24057.1 - 0.024 13.4 0.0 0.036 12.8 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Terminase_6 PF03237.10 EWM24057.1 - 0.048 12.4 0.1 3 6.5 0.0 2.7 3 0 0 3 3 3 0 Terminase-like family NUDIX PF00293.23 EWM24058.1 - 8.1e-20 70.8 0.0 1e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain API5 PF05918.6 EWM24060.1 - 0.12 10.8 6.5 0.13 10.7 4.5 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Myc_N PF01056.13 EWM24060.1 - 0.41 9.7 4.7 0.45 9.6 3.2 1.1 1 0 0 1 1 1 0 Myc amino-terminal region SelP_N PF04592.9 EWM24060.1 - 1.1 8.5 8.0 1.2 8.4 5.5 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.17 EWM24060.1 - 2 7.3 9.1 2.3 7.1 6.3 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter TIL PF01826.12 EWM24061.1 - 5.1e-07 29.7 16.3 8.1e-07 29.0 11.3 1.3 1 0 0 1 1 1 1 Trypsin Inhibitor like cysteine rich domain TIL PF01826.12 EWM24062.1 - 2.2e-07 30.8 16.3 3.3e-07 30.3 11.3 1.3 1 0 0 1 1 1 1 Trypsin Inhibitor like cysteine rich domain 2OG-FeII_Oxy_3 PF13640.1 EWM24063.1 - 2.1e-10 40.9 0.0 7.2e-10 39.2 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EWM24063.1 - 2e-07 31.2 0.0 3.2e-06 27.3 0.0 2.6 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EWM24063.1 - 0.031 13.9 0.0 0.093 12.3 0.0 1.8 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Sec10 PF07393.6 EWM24065.1 - 0.14 10.3 0.1 0.19 9.8 0.1 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 Methyltrans_SAM PF10672.4 EWM24066.1 - 2e-19 69.5 0.0 2.8e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase Methyltransf_31 PF13847.1 EWM24066.1 - 1.6e-12 47.2 0.0 3.2e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM24066.1 - 1.8e-10 40.8 0.2 5.1e-10 39.4 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EWM24066.1 - 4.8e-09 35.8 0.0 8e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.2 EWM24066.1 - 6.2e-09 36.4 0.0 1.3e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EWM24066.1 - 5.1e-07 29.4 0.0 8.8e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 MTS PF05175.9 EWM24066.1 - 5.7e-07 29.0 0.0 9.7e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EWM24066.1 - 1.8e-06 27.3 0.0 2.7e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 EWM24066.1 - 0.00012 22.3 0.0 0.00025 21.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EWM24066.1 - 0.00014 21.5 0.0 0.00023 20.7 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.11 EWM24066.1 - 0.00045 19.8 0.0 0.00078 19.0 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein PUA PF01472.15 EWM24066.1 - 0.012 15.2 0.1 0.033 13.9 0.1 1.7 2 0 0 2 2 2 0 PUA domain Methyltransf_11 PF08241.7 EWM24066.1 - 0.05 14.0 0.0 0.31 11.5 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Epimerase PF01370.16 EWM24067.1 - 3.3e-41 141.2 0.0 4.1e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EWM24067.1 - 2.2e-09 36.4 0.0 3.3e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EWM24067.1 - 2.2e-07 30.0 0.0 2.8e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EWM24067.1 - 1e-06 27.8 0.0 4.6e-05 22.4 0.0 2.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EWM24067.1 - 1.9e-06 28.0 0.0 2.9e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EWM24067.1 - 3.2e-05 22.9 0.0 0.0023 16.9 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 EWM24067.1 - 0.013 15.4 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase CPSase_L_chain PF00289.17 EWM24067.1 - 0.1 12.6 0.0 0.36 10.9 0.0 1.9 1 1 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain ABM PF03992.11 EWM24067.1 - 0.13 12.3 0.0 0.65 10.0 0.0 2.1 1 1 1 2 2 2 0 Antibiotic biosynthesis monooxygenase NmrA PF05368.8 EWM24067.1 - 0.13 11.4 0.0 1.5 8.0 0.0 2.3 2 1 0 2 2 2 0 NmrA-like family NAD_binding_7 PF13241.1 EWM24067.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Proteasome PF00227.21 EWM24068.1 - 1.3e-48 164.7 0.6 1.9e-48 164.2 0.4 1.2 1 0 0 1 1 1 1 Proteasome subunit SelA PF03841.8 EWM24068.1 - 0.043 12.5 0.0 0.062 12.0 0.0 1.1 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase DENN PF02141.16 EWM24069.1 - 1.7e-30 106.1 2.3 1.9e-28 99.4 1.6 2.6 1 1 0 1 1 1 1 DENN (AEX-3) domain RGS PF00615.14 EWM24069.1 - 2.3e-06 27.7 0.0 0.0065 16.5 0.0 2.5 2 0 0 2 2 2 2 Regulator of G protein signaling domain PDZ PF00595.19 EWM24069.1 - 0.004 17.3 0.0 0.0082 16.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EWM24069.1 - 0.075 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 PDZ domain CBF PF03914.12 EWM24070.1 - 3.5e-30 104.6 1.5 8.2e-30 103.4 0.1 2.4 2 1 0 2 2 2 1 CBF/Mak21 family Aminotran_1_2 PF00155.16 EWM24071.1 - 1.3e-34 119.8 0.0 1.7e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EWM24071.1 - 1.8e-06 26.9 0.0 2.5e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EWM24071.1 - 0.00019 20.6 0.0 0.00026 20.2 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase SKN1 PF03935.10 EWM24072.1 - 4.3e-22 77.9 0.8 6.1e-10 37.8 0.1 3.1 2 1 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.16 EWM24072.1 - 5.4e-06 25.8 0.1 3.6e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 EGF_2 PF07974.8 EWM24072.1 - 0.00013 22.0 10.3 0.00013 22.0 7.2 3.7 3 1 0 3 3 3 1 EGF-like domain Kua-UEV1_localn PF10520.4 EWM24073.1 - 3.3e-16 59.4 0.0 5.1e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Kua-ubiquitin conjugating enzyme hybrid localisation domain FA_hydroxylase PF04116.8 EWM24073.1 - 0.011 16.0 4.4 0.089 13.2 0.0 2.5 2 2 0 2 2 2 0 Fatty acid hydroxylase superfamily Kua-UEV1_localn PF10520.4 EWM24074.1 - 3.3e-16 59.4 0.0 5.1e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Kua-ubiquitin conjugating enzyme hybrid localisation domain FA_hydroxylase PF04116.8 EWM24074.1 - 0.011 16.0 4.4 0.089 13.2 0.0 2.5 2 2 0 2 2 2 0 Fatty acid hydroxylase superfamily ELFV_dehydrog PF00208.16 EWM24075.1 - 6e-41 140.6 0.0 7.9e-41 140.2 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EWM24075.1 - 3e-33 114.1 0.0 5.1e-33 113.4 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 EWM24075.1 - 0.029 14.6 0.0 0.059 13.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Oxidored_nitro PF00148.14 EWM24075.1 - 0.039 12.6 0.0 0.061 11.9 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase adh_short PF00106.20 EWM24075.1 - 0.048 13.5 0.0 0.098 12.5 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase RdRP PF05183.7 EWM24076.1 - 8.9e-08 31.2 0.0 0.0002 20.1 0.0 2.8 2 1 1 3 3 3 2 RNA dependent RNA polymerase SKN1 PF03935.10 EWM24077.1 - 5.2e-23 80.9 0.1 1.2e-22 79.8 0.1 1.4 1 1 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Rubis-subs-bind PF09273.6 EWM24078.1 - 1.4e-18 67.0 1.1 2.6e-18 66.1 0.8 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.23 EWM24078.1 - 1.6e-08 35.0 0.0 1e-07 32.4 0.0 2.3 1 1 0 1 1 1 1 SET domain Aldedh PF00171.17 EWM24081.1 - 7.9e-06 24.4 0.0 1.5e-05 23.5 0.0 1.3 1 1 0 1 1 1 1 Aldehyde dehydrogenase family TFIIF_beta PF02270.10 EWM24082.1 - 0.039 13.7 1.9 0.051 13.3 1.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, beta subunit Nckap1 PF09735.4 EWM24082.1 - 0.09 10.2 0.3 0.12 9.8 0.2 1.1 1 0 0 1 1 1 0 Membrane-associated apoptosis protein TPR_MLP1_2 PF07926.7 EWM24082.1 - 0.36 10.5 18.0 2.1 8.0 6.9 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF605 PF04652.11 EWM24082.1 - 1.3 8.3 6.1 1.7 7.9 4.3 1.2 1 0 0 1 1 1 0 Vta1 like Pex14_N PF04695.8 EWM24084.1 - 8.1e-23 80.9 0.0 1e-22 80.6 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF303 PF03629.13 EWM24089.1 - 4.9e-12 45.6 0.0 6.6e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF303) Pkinase_Tyr PF07714.12 EWM24092.1 - 1.5e-06 27.5 0.0 1.7e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase CBFD_NFYB_HMF PF00808.18 EWM24094.1 - 1.9e-05 24.6 0.0 2.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone B_lectin PF01453.19 EWM24095.1 - 2.1e-05 24.3 0.0 3.6e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 D-mannose binding lectin Transket_pyr PF02779.19 EWM24096.1 - 1.3e-09 37.7 0.1 1.8e-09 37.3 0.1 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Peptidase_S41 PF03572.13 EWM24100.1 - 2.2e-41 141.0 0.2 3.4e-41 140.4 0.2 1.3 1 0 0 1 1 1 1 Peptidase family S41 PDZ PF00595.19 EWM24100.1 - 1.1e-09 38.3 0.1 2.3e-09 37.2 0.1 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EWM24100.1 - 3.5e-07 30.0 0.1 8.6e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain SUV3_C PF12513.3 EWM24104.1 - 1.5e-12 46.7 0.0 4e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 EWM24104.1 - 4.7e-09 35.9 0.1 1.1e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pkinase PF00069.20 EWM24105.1 - 1.1e-61 208.3 0.0 1.8e-61 207.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM24105.1 - 1.4e-38 132.4 0.0 1.9e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EWM24105.1 - 7.6e-05 21.8 0.0 0.00014 20.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like CDV3 PF15359.1 EWM24105.1 - 0.012 15.7 2.8 0.025 14.6 2.0 1.5 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 APH PF01636.18 EWM24105.1 - 0.012 15.3 0.8 0.012 15.3 0.5 3.1 2 2 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EWM24105.1 - 0.055 12.2 0.0 0.088 11.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 GAGA_bind PF06217.7 EWM24105.1 - 0.53 10.2 7.5 0.77 9.6 5.2 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family TFIIA PF03153.8 EWM24105.1 - 0.54 10.0 9.0 0.8 9.5 6.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1510 PF07423.6 EWM24105.1 - 7 5.9 11.1 12 5.1 7.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) F-box-like PF12937.2 EWM24106.1 - 0.0012 18.5 1.1 0.0029 17.2 0.8 1.7 1 0 0 1 1 1 1 F-box-like Cupin_3 PF05899.7 EWM24108.1 - 1.1e-07 31.0 0.4 2e-07 30.3 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) UPF0444 PF15475.1 EWM24109.1 - 1.5 8.9 9.2 0.072 13.1 0.6 3.2 3 0 0 3 3 3 0 Transmembrane protein C12orf23, UPF0444 SNARE_assoc PF09335.6 EWM24111.1 - 0.0048 17.0 1.8 0.0085 16.2 0.5 1.9 2 0 0 2 2 2 1 SNARE associated Golgi protein Pkinase PF00069.20 EWM24112.1 - 6.8e-08 31.9 0.0 1.1e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EWM24112.1 - 2.4e-07 30.7 1.5 0.006 16.3 0.2 2.6 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EWM24112.1 - 0.00059 18.9 0.0 0.00098 18.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SNARE_assoc PF09335.6 EWM24113.1 - 0.096 12.8 0.6 0.59 10.3 0.1 2.1 2 0 0 2 2 2 0 SNARE associated Golgi protein Rubredoxin PF00301.15 EWM24114.1 - 1.6e-14 53.5 5.0 2.5e-14 52.8 3.4 1.3 1 0 0 1 1 1 1 Rubredoxin Elf1 PF05129.8 EWM24114.1 - 0.024 14.3 0.6 3.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.5 EWM24114.1 - 0.6 10.1 2.4 23 5.0 0.0 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-Mss51 PF13824.1 EWM24114.1 - 0.7 9.7 2.7 22 5.0 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Rieske_2 PF13806.1 EWM24115.1 - 0.0017 18.0 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.21 EWM24115.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain PMSR PF01625.16 EWM24116.1 - 7.3e-25 87.6 0.1 1.2e-24 86.9 0.1 1.3 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase PMSR PF01625.16 EWM24117.1 - 1.3e-61 207.0 0.1 1.9e-61 206.5 0.1 1.2 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Complex1_30kDa PF00329.14 EWM24117.1 - 0.076 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Pyr_redox_2 PF07992.9 EWM24119.1 - 6.6e-08 32.6 0.0 8.6e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EWM24119.1 - 0.0057 16.4 0.0 0.037 13.8 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding FBPase PF00316.15 EWM24122.1 - 1.6e-12 46.9 0.0 1.8e-12 46.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Daxx PF03344.10 EWM24125.1 - 0.0039 15.7 22.0 0.0042 15.6 15.3 1.0 1 0 0 1 1 1 1 Daxx Family BSP_II PF05432.6 EWM24125.1 - 0.039 13.2 22.5 0.046 13.0 15.6 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Spore_coat_CotO PF14153.1 EWM24125.1 - 0.06 12.7 7.3 0.066 12.6 5.1 1.1 1 0 0 1 1 1 0 Spore coat protein CotO RNA_pol_Rpc4 PF05132.9 EWM24125.1 - 0.095 12.6 3.1 0.12 12.3 2.1 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 CDC45 PF02724.9 EWM24125.1 - 0.14 10.2 15.5 0.15 10.0 10.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EWM24125.1 - 0.27 9.1 23.2 0.29 8.9 16.1 1.0 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.7 EWM24125.1 - 0.28 9.4 22.6 0.32 9.3 15.7 1.0 1 0 0 1 1 1 0 Mpp10 protein PPP4R2 PF09184.6 EWM24125.1 - 0.41 10.1 20.3 0.48 9.9 14.1 1.1 1 0 0 1 1 1 0 PPP4R2 DUF2722 PF10846.3 EWM24125.1 - 0.47 9.4 4.4 0.52 9.2 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) YqfQ PF14181.1 EWM24125.1 - 0.76 9.7 7.1 1 9.4 4.9 1.2 1 0 0 1 1 1 0 YqfQ-like protein BUD22 PF09073.5 EWM24125.1 - 0.85 8.6 14.9 0.86 8.6 10.3 1.1 1 0 0 1 1 1 0 BUD22 DUF1510 PF07423.6 EWM24125.1 - 0.99 8.7 16.4 1.2 8.4 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Sporozoite_P67 PF05642.6 EWM24125.1 - 1.1 7.0 9.2 1.4 6.6 6.4 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2151 PF10221.4 EWM24125.1 - 1.2 7.2 5.7 1.2 7.2 4.0 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator alpha-hel2 PF14456.1 EWM24125.1 - 1.4 7.6 12.2 1.7 7.3 8.4 1.1 1 0 0 1 1 1 0 Alpha-helical domain 2 Vfa1 PF08432.5 EWM24125.1 - 1.4 8.9 8.6 1.8 8.5 6.0 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Upf2 PF04050.9 EWM24125.1 - 1.5 8.5 19.1 1.9 8.1 13.2 1.2 1 0 0 1 1 1 0 Up-frameshift suppressor 2 Prothymosin PF03247.9 EWM24125.1 - 1.8 8.7 33.9 3.2 7.9 23.5 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family SDA1 PF05285.7 EWM24125.1 - 1.9 7.6 20.9 2.1 7.5 14.5 1.1 1 0 0 1 1 1 0 SDA1 TEX19 PF15553.1 EWM24125.1 - 2 8.2 9.3 2.5 7.9 6.4 1.2 1 0 0 1 1 1 0 Testis-expressed protein 19 NOA36 PF06524.7 EWM24125.1 - 2 7.5 15.6 2.4 7.3 10.8 1.1 1 0 0 1 1 1 0 NOA36 protein CENP-T PF15511.1 EWM24125.1 - 2.1 7.4 11.8 2.3 7.3 8.2 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Pox_Ag35 PF03286.9 EWM24125.1 - 2.2 7.7 10.4 2.9 7.3 7.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Ycf1 PF05758.7 EWM24125.1 - 2.3 5.7 6.8 2.3 5.8 4.7 1.0 1 0 0 1 1 1 0 Ycf1 Sigma70_ner PF04546.8 EWM24125.1 - 2.7 7.5 18.2 3.7 7.1 12.6 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2457 PF10446.4 EWM24125.1 - 3.2 6.3 23.4 4.1 6.0 16.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) GRP PF07172.6 EWM24125.1 - 3.3 8.2 12.0 6 7.4 8.3 1.4 1 1 0 1 1 1 0 Glycine rich protein family RRN3 PF05327.6 EWM24125.1 - 4.3 5.3 11.9 5 5.1 8.3 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 IFT57 PF10498.4 EWM24125.1 - 4.5 5.9 9.8 5 5.7 6.8 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Merozoite_SPAM PF07133.6 EWM24125.1 - 5.1 6.9 27.0 6.4 6.6 18.7 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) TFIIF_alpha PF05793.7 EWM24125.1 - 5.3 5.2 24.6 6 5.1 17.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pox_RNA_Pol_19 PF05320.7 EWM24125.1 - 5.6 6.6 13.3 8 6.1 9.2 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit ERF PF04404.7 EWM24125.1 - 6.6 6.2 6.8 11 5.4 4.7 1.3 1 0 0 1 1 1 0 ERF superfamily VID27 PF08553.5 EWM24125.1 - 6.8 4.7 18.8 8.1 4.5 13.0 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein XAP5 PF04921.9 EWM24125.1 - 6.9 6.1 8.9 8.3 5.8 6.2 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator DUF3381 PF11861.3 EWM24125.1 - 7.8 5.9 16.3 11 5.5 11.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Radial_spoke PF04712.7 EWM24125.1 - 8 5.0 20.3 9.5 4.8 14.1 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Rad54_N PF08658.5 EWM24125.1 - 9.6 5.9 7.4 12 5.6 5.1 1.2 1 0 0 1 1 1 0 Rad54 N terminal Peptidase_C1 PF00112.18 EWM24126.1 - 0.0057 16.5 0.0 0.0068 16.3 0.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Ribosomal_L28e PF01778.12 EWM24128.1 - 1.7e-30 105.8 0.4 2.2e-30 105.4 0.3 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Transglut_core PF01841.14 EWM24130.1 - 0.0044 17.2 0.0 0.008 16.3 0.0 1.5 1 1 0 1 1 1 1 Transglutaminase-like superfamily Methyltransf_18 PF12847.2 EWM24131.1 - 2.8e-09 37.5 0.0 4.7e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM24131.1 - 3.1e-08 33.5 0.0 1.4e-07 31.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM24131.1 - 1.2e-07 32.1 0.0 2.4e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM24131.1 - 3e-07 30.8 0.0 5.1e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM24131.1 - 3.7e-05 24.0 0.0 9.5e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM24131.1 - 8.2e-05 22.6 0.6 0.0002 21.3 0.4 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM24131.1 - 0.00014 21.4 0.0 0.00037 20.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 EWM24131.1 - 0.0053 16.3 0.2 2.3 7.7 0.1 2.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase CMAS PF02353.15 EWM24131.1 - 0.026 13.6 0.0 0.038 13.0 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF938 PF06080.7 EWM24131.1 - 0.029 13.9 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_32 PF13679.1 EWM24131.1 - 0.038 13.6 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.13 EWM24131.1 - 0.11 11.7 0.0 0.31 10.3 0.0 1.6 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Fis1_TPR_C PF14853.1 EWM24132.1 - 7.7e-07 28.8 0.2 1.4e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.12 EWM24132.1 - 7.3e-05 22.3 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 EWM24132.1 - 0.0017 18.4 0.4 0.0034 17.4 0.3 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EWM24132.1 - 0.0022 18.3 0.0 0.0062 16.9 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 EWM24132.1 - 0.0057 16.9 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 EWM24132.1 - 0.011 15.3 0.1 0.029 14.0 0.1 1.7 1 1 1 2 2 2 0 TPR repeat SKG6 PF08693.5 EWM24132.1 - 0.031 13.5 0.9 0.055 12.7 0.7 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Prenyltrans PF00432.16 EWM24136.1 - 2e-26 91.1 7.2 1e-12 47.3 0.1 3.2 3 0 0 3 3 3 2 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EWM24136.1 - 5.4e-22 78.3 0.0 2.2e-14 53.8 0.0 2.2 1 1 1 2 2 2 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 EWM24136.1 - 1.3e-12 47.6 0.0 1.1e-06 28.5 0.0 2.2 1 1 1 2 2 2 2 Prenyltransferase-like AAA PF00004.24 EWM24137.1 - 9.6e-11 42.0 0.0 1.3e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EWM24137.1 - 3.5e-08 33.2 0.0 6.5e-06 25.9 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.1 EWM24137.1 - 3.6e-07 30.3 1.1 0.013 15.6 0.1 2.2 1 1 1 2 2 2 2 AAA domain Rad17 PF03215.10 EWM24137.1 - 2.7e-06 26.3 0.0 2.8e-06 26.2 0.0 1.2 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 EWM24137.1 - 1e-05 24.7 0.0 1.4e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 EWM24137.1 - 3.4e-05 23.5 0.0 8.5e-05 22.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EWM24137.1 - 0.00012 21.9 0.0 0.00017 21.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EWM24137.1 - 0.00015 21.4 0.0 0.00023 20.8 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_3 PF07726.6 EWM24137.1 - 0.00018 21.0 0.0 0.00026 20.5 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EWM24137.1 - 0.00021 21.3 0.4 0.00099 19.1 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 EWM24137.1 - 0.00035 20.3 0.0 0.00043 20.0 0.0 1.1 1 0 0 1 1 1 1 Archaeal ATPase DUF815 PF05673.8 EWM24137.1 - 0.00056 18.9 0.0 0.0007 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ResIII PF04851.10 EWM24137.1 - 0.0009 19.1 0.1 0.091 12.5 0.0 2.1 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_5 PF07728.9 EWM24137.1 - 0.00093 18.9 0.1 0.0077 15.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EWM24137.1 - 0.0014 18.0 0.5 0.033 13.5 0.0 2.2 1 1 1 2 2 2 1 AAA domain DEAD PF00270.24 EWM24137.1 - 0.0015 18.0 0.4 0.021 14.3 0.1 2.1 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_10 PF12846.2 EWM24137.1 - 0.0016 17.9 0.2 1.2 8.5 0.0 2.2 1 1 1 2 2 2 2 AAA-like domain AAA_24 PF13479.1 EWM24137.1 - 0.0036 16.9 0.0 0.0062 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 EWM24137.1 - 0.0095 15.1 0.1 0.18 10.9 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_30 PF13604.1 EWM24137.1 - 0.0096 15.5 0.1 0.034 13.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EWM24137.1 - 0.014 14.7 0.2 0.03 13.7 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein KaiC PF06745.8 EWM24137.1 - 0.015 14.4 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 KaiC TIP49 PF06068.8 EWM24137.1 - 0.016 13.9 0.0 0.02 13.6 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 EWM24137.1 - 0.038 13.1 0.2 0.23 10.6 0.1 2.1 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 EWM24137.1 - 0.063 12.2 0.3 0.35 9.7 0.2 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.1 EWM24137.1 - 0.11 12.3 0.1 0.2 11.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EWM24137.1 - 0.12 11.2 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_17 PF13207.1 EWM24137.1 - 0.12 13.1 0.0 0.25 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain PsbP PF01789.11 EWM24138.1 - 1.6e-21 76.5 0.0 9e-15 54.5 0.0 2.1 2 0 0 2 2 2 2 PsbP PLRV_ORF5 PF01690.12 EWM24138.1 - 2.4 7.2 9.4 3.7 6.5 6.5 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein START PF01852.14 EWM24139.1 - 0.0065 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 START domain Sulfate_transp PF00916.15 EWM24140.1 - 6.8e-46 156.5 1.4 1.3e-45 155.5 1.0 1.5 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EWM24140.1 - 2.8e-19 68.5 1.9 2.8e-19 68.5 1.3 2.8 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EWM24140.1 - 1.1e-11 44.1 0.0 2.3e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EWM24140.1 - 0.017 15.1 1.2 0.067 13.2 0.8 2.0 1 0 0 1 1 1 0 STAS domain Sulfate_transp PF00916.15 EWM24141.1 - 6.4e-46 156.6 1.7 1.1e-45 155.8 1.2 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EWM24141.1 - 2.3e-19 68.8 1.9 2.3e-19 68.8 1.3 2.8 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EWM24141.1 - 0.16 11.3 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 STAS domain DUF2668 PF10873.3 EWM24144.1 - 9.5 6.3 9.9 12 6.0 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) Lipase_3 PF01764.20 EWM24145.1 - 2.6e-10 40.0 0.0 7.7e-09 35.2 0.0 2.2 1 1 1 2 2 2 2 Lipase (class 3) Mod_r PF07200.8 EWM24147.1 - 9.5e-19 67.7 1.8 1.5e-18 67.1 1.2 1.3 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein EzrA PF06160.7 EWM24147.1 - 0.015 13.5 0.5 0.019 13.2 0.3 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Not3 PF04065.10 EWM24147.1 - 0.11 11.7 2.0 0.11 11.7 0.2 1.6 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component Nup84_Nup100 PF04121.8 EWM24147.1 - 0.12 9.9 0.6 0.17 9.5 0.4 1.1 1 0 0 1 1 1 0 Nuclear pore protein 84 / 107 FCH PF00611.18 EWM24147.1 - 0.2 11.8 1.6 0.35 11.0 0.1 2.1 2 1 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain IncA PF04156.9 EWM24147.1 - 0.69 9.4 3.4 1 8.9 2.3 1.5 1 1 0 1 1 1 0 IncA protein Polysacc_synt_3 PF13440.1 EWM24148.1 - 0.098 12.1 0.4 0.21 10.9 0.3 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DUF599 PF04654.7 EWM24149.1 - 0.0041 16.3 5.6 0.0079 15.3 3.9 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF599 SdpI PF13630.1 EWM24149.1 - 0.32 10.7 0.0 0.32 10.7 0.0 2.9 4 0 0 4 4 4 0 SdpI/YhfL protein family Troponin-I_N PF11636.3 EWM24152.1 - 4.3 7.1 10.0 9.6 6.0 7.0 1.7 1 0 0 1 1 1 0 Troponin I residues 1-32 Acyl-CoA_dh_N PF02771.11 EWM24154.1 - 1.3e-38 132.0 0.0 2.2e-38 131.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EWM24154.1 - 5.9e-20 70.5 0.7 1.2e-19 69.5 0.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DsbB PF02600.11 EWM24155.1 - 0.037 13.8 0.3 3 7.6 0.1 2.1 2 0 0 2 2 2 0 Disulfide bond formation protein DsbB PAT1 PF09770.4 EWM24156.1 - 1.4 7.0 139.8 0.03 12.5 87.0 2.3 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF500 PF04366.7 EWM24157.1 - 1.2e-15 57.0 0.0 2.1e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) PPP4R2 PF09184.6 EWM24157.1 - 0.06 12.8 4.1 0.07 12.6 2.8 1.1 1 0 0 1 1 1 0 PPP4R2 DUF2201_N PF13203.1 EWM24157.1 - 0.31 10.1 5.7 0.44 9.6 4.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Ubie_methyltran PF01209.13 EWM24158.1 - 2.9e-77 258.9 0.0 3.7e-77 258.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 EWM24158.1 - 1.8e-15 57.1 0.0 3.4e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM24158.1 - 4.1e-13 49.2 0.0 7.5e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM24158.1 - 1.1e-11 45.0 0.0 4e-11 43.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM24158.1 - 1.8e-08 34.9 0.0 3.2e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM24158.1 - 5.1e-08 32.8 0.0 7.6e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM24158.1 - 5.5e-06 26.7 0.0 1.2e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM24158.1 - 0.00027 20.9 0.3 0.00058 19.8 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain NMT1_2 PF13379.1 EWM24158.1 - 0.086 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 NMT1-like family Methyltransf_8 PF05148.10 EWM24158.1 - 0.17 11.5 0.0 0.37 10.3 0.0 1.6 2 0 0 2 2 2 0 Hypothetical methyltransferase Mito_fiss_reg PF05308.6 EWM24158.1 - 0.54 9.5 7.3 0.77 9.0 5.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF566 PF04484.7 EWM24158.1 - 2 7.8 7.9 2.9 7.3 5.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF605 PF04652.11 EWM24158.1 - 8.3 5.6 13.1 11 5.2 9.1 1.1 1 0 0 1 1 1 0 Vta1 like DUF1365 PF07103.6 EWM24159.1 - 3.3e-50 170.5 0.0 9e-50 169.0 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1365) NeA_P2 PF12312.3 EWM24159.1 - 0.045 12.9 1.1 0.078 12.2 0.8 1.3 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein TGT PF01702.13 EWM24160.1 - 8.6e-78 260.8 0.0 1e-77 260.6 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Glutaredoxin PF00462.19 EWM24161.1 - 7.8e-17 61.0 0.0 1.2e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin PepSY_2 PF13670.1 EWM24162.1 - 0.021 14.7 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Big_3_4 PF13754.1 EWM24162.1 - 0.08 13.2 5.2 0.45 10.8 3.5 2.2 1 1 1 2 2 2 0 Bacterial Ig-like domain (group 3) PepSY_2 PF13670.1 EWM24163.1 - 0.0079 16.0 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain Big_3_4 PF13754.1 EWM24163.1 - 0.075 13.3 5.2 0.46 10.8 3.5 2.2 1 1 0 1 1 1 0 Bacterial Ig-like domain (group 3) HlyIII PF03006.15 EWM24164.1 - 2.3e-21 76.2 11.6 2.7e-21 76.0 8.0 1.0 1 0 0 1 1 1 1 Haemolysin-III related Ceramidase PF05875.7 EWM24164.1 - 0.012 14.7 5.1 0.016 14.3 3.5 1.2 1 0 0 1 1 1 0 Ceramidase Kazal_1 PF00050.16 EWM24165.1 - 4.2e-19 68.3 23.9 1.2e-06 28.4 2.3 3.6 3 0 0 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 EWM24165.1 - 1.8e-18 66.2 22.9 2.3e-07 30.6 1.5 3.5 3 0 0 3 3 3 3 Kazal-type serine protease inhibitor domain DSL PF01414.14 EWM24165.1 - 6.6 6.8 11.8 6.6 6.8 0.3 3.7 3 0 0 3 3 3 0 Delta serrate ligand Kazal_2 PF07648.10 EWM24166.1 - 2.5e-18 65.6 22.9 3e-07 30.2 1.5 3.8 3 0 0 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 EWM24166.1 - 4e-18 65.1 30.7 3.9e-07 29.9 1.0 4.1 4 0 0 4 4 4 3 Kazal-type serine protease inhibitor domain Nodulin_late PF07127.6 EWM24166.1 - 2.1 8.5 6.3 0.23 11.5 0.3 2.4 2 1 1 3 3 3 0 Late nodulin protein MFS_1 PF07690.11 EWM24167.1 - 3.7e-19 68.6 31.8 2.6e-18 65.8 22.1 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EWM24167.1 - 0.00086 19.0 0.3 0.00086 19.0 0.2 2.6 3 0 0 3 3 3 1 MFS_1 like family MFS_2 PF13347.1 EWM24167.1 - 0.028 12.8 9.1 0.026 12.9 1.6 2.2 2 0 0 2 2 2 0 MFS/sugar transport protein HlyIII PF03006.15 EWM24168.1 - 3.2e-14 52.8 3.3 4.5e-14 52.3 2.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.6 EWM24168.1 - 0.17 11.8 0.8 0.25 11.2 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF962) DUF1213 PF06740.7 EWM24169.1 - 0.89 9.7 9.2 24 5.1 0.1 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1213) PepSY_TM_3 PF13706.1 EWM24171.1 - 0.09 12.2 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 PepSY-associated TM helix KAR9 PF08580.5 EWM24171.1 - 0.3 9.3 2.6 0.44 8.7 1.8 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Ank PF00023.25 EWM24172.1 - 9.7e-30 100.8 0.4 2.6e-08 33.2 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 EWM24172.1 - 2e-24 85.7 0.0 2.9e-13 49.9 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EWM24172.1 - 1.3e-22 79.3 0.6 1.4e-06 28.3 0.0 5.1 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM24172.1 - 1.2e-17 62.2 0.1 0.00012 21.9 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 EWM24172.1 - 1.5e-14 54.0 0.3 4.2e-07 30.3 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) DXPR_C PF13288.1 EWM24174.1 - 3.2e-16 59.4 0.2 3.6e-16 59.2 0.2 1.1 1 0 0 1 1 1 1 DXP reductoisomerase C-terminal domain Phage_30_8 PF06019.6 EWM24174.1 - 0.039 13.6 0.2 0.054 13.1 0.1 1.3 1 1 0 1 1 1 0 Phage GP30.8 protein DXP_reductoisom PF02670.11 EWM24175.1 - 8.9e-11 42.4 0.0 1.6e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Peptidase_M50 PF02163.17 EWM24176.1 - 2.8e-05 23.1 1.9 0.0031 16.5 1.4 2.3 1 1 0 1 1 1 1 Peptidase family M50 DUF1275 PF06912.6 EWM24177.1 - 3e-17 62.5 5.9 4.1e-17 62.0 4.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) HSF_DNA-bind PF00447.12 EWM24178.1 - 6e-29 100.2 0.0 9.5e-29 99.6 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Chal_sti_synt_C PF02797.10 EWM24178.1 - 0.08 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain CTP_transf_1 PF01148.15 EWM24180.1 - 0.00094 18.9 17.1 0.00094 18.9 11.8 3.6 2 1 1 3 3 3 1 Cytidylyltransferase family Acetyltransf_3 PF13302.1 EWM24181.1 - 2.9e-27 95.5 0.0 6.8e-27 94.3 0.0 1.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EWM24181.1 - 2.8e-09 36.8 0.0 4.5e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EWM24181.1 - 1.7e-08 34.4 0.0 2.6e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EWM24181.1 - 1.6e-06 28.1 0.0 2.8e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EWM24181.1 - 3.3e-05 23.5 0.0 5.7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EWM24181.1 - 0.012 15.7 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DEAD PF00270.24 EWM24183.1 - 1.7e-33 115.5 0.0 2.6e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EWM24183.1 - 5.7e-21 74.1 0.0 1.9e-20 72.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EWM24183.1 - 0.00062 19.6 0.0 0.00094 19.0 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.9 EWM24183.1 - 0.0064 15.1 0.0 0.0099 14.4 0.0 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer AAA_19 PF13245.1 EWM24183.1 - 0.06 13.1 3.2 0.076 12.7 0.7 2.4 2 0 0 2 2 2 0 Part of AAA domain DUF3807 PF12720.2 EWM24184.1 - 5.6 7.0 12.5 6.3 6.9 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Gti1_Pac2 PF09729.4 EWM24184.1 - 6.7 6.5 11.5 8.9 6.1 8.0 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family Pkinase PF00069.20 EWM24185.1 - 9.3e-63 211.7 0.0 1.3e-62 211.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM24185.1 - 8.3e-33 113.5 0.0 1.1e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EWM24185.1 - 1.1e-07 31.1 0.0 5.5e-07 28.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EWM24185.1 - 0.00021 20.4 0.0 0.00048 19.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EWM24185.1 - 0.0028 17.0 0.0 0.0089 15.3 0.0 1.7 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL APH PF01636.18 EWM24185.1 - 0.0053 16.5 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EWM24185.1 - 0.0055 16.0 0.0 0.0093 15.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Phasin PF05597.6 EWM24185.1 - 0.027 14.2 0.1 0.079 12.7 0.0 1.7 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Choline_kinase PF01633.15 EWM24185.1 - 0.073 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase PAH PF02671.16 EWM24186.1 - 1.1e-66 220.2 0.1 5.3e-10 38.7 0.0 6.5 6 0 0 6 6 6 6 Paired amphipathic helix repeat Chlamy_scaf PF09675.5 EWM24186.1 - 0.12 12.4 0.2 9.7 6.2 0.0 3.3 4 0 0 4 4 4 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) PAH PF02671.16 EWM24187.1 - 7e-67 220.8 0.1 4.9e-10 38.8 0.0 6.5 6 0 0 6 6 6 6 Paired amphipathic helix repeat Chlamy_scaf PF09675.5 EWM24187.1 - 0.1 12.5 0.3 9 6.3 0.0 3.3 4 0 0 4 4 4 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) MinC_C PF03775.11 EWM24189.1 - 3e-23 81.4 2.4 5e-23 80.7 1.7 1.3 1 0 0 1 1 1 1 Septum formation inhibitor MinC, C-terminal domain DUF342 PF03961.8 EWM24189.1 - 8.4e-05 21.1 1.3 0.00011 20.7 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF342) Hormone_3 PF00159.13 EWM24189.1 - 0.16 11.9 2.8 0.44 10.5 1.9 1.7 1 0 0 1 1 1 0 Pancreatic hormone peptide TauD PF02668.11 EWM24190.1 - 6.5e-47 160.3 0.0 1.6e-46 159.0 0.0 1.6 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 EWM24190.1 - 2.3e-06 27.9 0.0 0.12 12.7 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF971) CsiD PF08943.5 EWM24190.1 - 0.0066 15.3 0.0 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 CsiD CorA PF01544.13 EWM24191.1 - 5.1e-10 38.8 2.1 5.1e-10 38.8 1.5 2.0 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein C2 PF00168.25 EWM24193.1 - 1e-08 34.9 0.0 1.8e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 C2 domain Abhydrolase_6 PF12697.2 EWM24194.1 - 1.5e-21 77.2 7.0 4.6e-21 75.7 4.9 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM24194.1 - 2e-09 37.3 0.1 1.6e-08 34.4 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EWM24194.1 - 0.00027 20.5 0.0 0.51 9.8 0.0 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 EWM24194.1 - 0.0013 18.6 0.0 0.0031 17.3 0.0 1.6 2 0 0 2 2 2 1 TAP-like protein Peptidase_S9 PF00326.16 EWM24194.1 - 0.0081 15.4 0.0 0.017 14.3 0.0 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.8 EWM24194.1 - 0.096 12.1 0.0 0.52 9.7 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Fer2 PF00111.22 EWM24195.1 - 1.2e-07 31.4 0.2 2.2e-07 30.5 0.2 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain SAP PF02037.22 EWM24196.1 - 1.6e-09 37.0 1.3 2.8e-09 36.2 0.9 1.4 1 0 0 1 1 1 1 SAP domain S1 PF00575.18 EWM24196.1 - 2.4e-05 24.3 0.2 4.1e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 S1 RNA binding domain RRM_1 PF00076.17 EWM24196.1 - 0.001 18.6 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM24196.1 - 0.002 18.0 0.0 0.0063 16.4 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1900 PF08954.6 EWM24197.1 - 2.2e-48 163.2 0.0 3.1e-48 162.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) WD40 PF00400.27 EWM24197.1 - 5.3e-23 80.0 0.2 6.1e-08 32.2 0.1 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF1899 PF08953.6 EWM24197.1 - 5.3e-20 70.8 0.1 9e-20 70.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) Nup160 PF11715.3 EWM24197.1 - 0.00074 17.7 0.2 0.37 8.8 0.0 2.7 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EWM24197.1 - 0.12 11.0 0.0 0.23 10.1 0.0 1.5 1 1 0 1 1 1 0 Nup133 N terminal like Serine_rich PF08824.5 EWM24198.1 - 0.0024 17.6 0.9 0.0024 17.6 0.6 3.0 1 1 2 3 3 3 1 Serine rich protein interaction domain Tropomyosin_1 PF12718.2 EWM24198.1 - 0.017 14.9 40.7 0.14 11.9 11.2 3.2 1 1 2 3 3 3 0 Tropomyosin like DUF244 PF03112.9 EWM24198.1 - 0.047 13.2 0.6 0.047 13.2 0.4 2.3 3 0 0 3 3 3 0 Uncharacterized protein family (ORF7) DUF TSC22 PF01166.13 EWM24198.1 - 0.11 12.4 0.2 0.11 12.4 0.2 4.5 5 1 0 5 5 5 0 TSC-22/dip/bun family YuzL PF14115.1 EWM24198.1 - 0.32 11.3 2.6 0.39 11.0 0.1 2.2 2 0 0 2 2 2 0 YuzL-like protein Fib_alpha PF08702.5 EWM24198.1 - 2.1 8.4 10.0 0.29 11.2 0.9 3.0 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Tropomyosin PF00261.15 EWM24198.1 - 4.3 6.3 45.5 2 7.4 17.3 2.9 1 1 0 2 2 2 0 Tropomyosin APG6 PF04111.7 EWM24198.1 - 9.3 5.1 35.7 0.13 11.2 11.6 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 Mito_carr PF00153.22 EWM24200.1 - 7.3e-24 83.2 0.1 1.7e-12 46.8 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Homoserine_dh PF00742.14 EWM24201.1 - 1.6e-55 187.5 0.1 3.3e-55 186.5 0.0 1.6 2 0 0 2 2 2 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EWM24201.1 - 6.2e-15 55.6 0.2 1.2e-14 54.6 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ACT PF01842.20 EWM24201.1 - 0.0086 15.5 0.1 0.025 14.0 0.1 1.8 1 0 0 1 1 1 1 ACT domain Pkinase PF00069.20 EWM24202.1 - 1.5e-39 135.7 0.0 1.8e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM24202.1 - 6.8e-24 84.3 0.0 8.9e-24 83.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EWM24202.1 - 7.6e-08 31.6 0.0 1e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EWM24202.1 - 0.28 9.9 0.0 0.4 9.4 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 DUF605 PF04652.11 EWM24202.1 - 7.7 5.8 22.9 11 5.2 15.9 1.2 1 0 0 1 1 1 0 Vta1 like Myosin_head PF00063.16 EWM24203.1 - 1.3e-188 628.3 0.0 1.4e-146 489.4 0.0 2.1 2 0 0 2 2 2 2 Myosin head (motor domain) AAA_22 PF13401.1 EWM24203.1 - 0.00023 21.3 1.2 0.0023 18.0 0.0 3.0 3 0 0 3 3 3 1 AAA domain IQ PF00612.22 EWM24203.1 - 0.00035 19.9 24.5 0.018 14.6 2.7 4.2 4 0 0 4 4 4 3 IQ calmodulin-binding motif DUF87 PF01935.12 EWM24203.1 - 0.012 15.4 0.6 1.7 8.4 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_30 PF13604.1 EWM24203.1 - 0.039 13.5 2.4 0.07 12.6 0.4 2.2 2 0 0 2 2 2 0 AAA domain DUF3600 PF12207.3 EWM24203.1 - 0.039 13.4 0.1 0.49 9.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3600) AAA_10 PF12846.2 EWM24203.1 - 0.099 12.0 0.2 0.48 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain ABC_tran PF00005.22 EWM24203.1 - 0.12 12.6 0.0 0.41 10.9 0.0 1.9 1 0 0 1 1 1 0 ABC transporter Kinesin PF00225.18 EWM24204.1 - 2.2e-104 348.7 0.0 3.6e-104 348.0 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain TPR_MLP1_2 PF07926.7 EWM24204.1 - 0.0027 17.4 38.3 0.12 12.1 2.4 4.4 3 1 0 4 4 4 4 TPR/MLP1/MLP2-like protein DEAD PF00270.24 EWM24204.1 - 0.016 14.6 0.0 0.044 13.2 0.0 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase DTW PF03942.10 EWM24207.1 - 1.9e-25 89.2 0.0 2.9e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 DTW domain Ndc80_HEC PF03801.8 EWM24208.1 - 5.3e-44 149.4 0.0 1.1e-43 148.3 0.0 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family AAA_13 PF13166.1 EWM24208.1 - 0.001 17.6 0.8 0.001 17.6 0.5 2.1 2 0 0 2 2 2 1 AAA domain HBS1_N PF08938.5 EWM24208.1 - 0.0019 18.2 1.3 0.0019 18.2 0.9 2.6 2 1 0 2 2 2 1 HBS1 N-terminus DUF4164 PF13747.1 EWM24208.1 - 0.02 15.0 4.2 0.02 15.0 2.9 4.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4164) Reo_sigmaC PF04582.7 EWM24208.1 - 0.038 13.1 2.6 0.29 10.2 0.0 2.7 2 1 0 2 2 2 0 Reovirus sigma C capsid protein Bacillus_HBL PF05791.6 EWM24208.1 - 0.097 12.0 7.0 0.29 10.5 1.5 2.9 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) V_ATPase_I PF01496.14 EWM24208.1 - 2.2 6.0 16.0 5.5 4.7 11.1 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EWM24208.1 - 2.3 7.7 28.7 0.26 10.8 5.8 3.5 2 2 1 3 3 3 0 IncA protein DUF948 PF06103.6 EWM24208.1 - 2.8 7.8 7.1 10 6.0 1.1 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) APG6 PF04111.7 EWM24208.1 - 3.8 6.4 29.8 0.25 10.3 6.0 3.4 2 2 2 4 4 4 0 Autophagy protein Apg6 Syntaxin-6_N PF09177.6 EWM24208.1 - 5.4 7.4 12.9 2 8.8 0.3 4.2 2 2 2 4 4 4 0 Syntaxin 6, N-terminal DUF802 PF05650.6 EWM24208.1 - 8 6.6 11.5 3.3 7.8 0.1 3.8 4 0 0 4 4 3 0 Domain of unknown function (DUF802) TMPIT PF07851.8 EWM24208.1 - 8.9 5.2 8.7 7.9 5.4 0.1 2.4 2 0 0 2 2 2 0 TMPIT-like protein ELMO_CED12 PF04727.8 EWM24209.1 - 4e-20 72.0 0.0 5.9e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family NAD_Gly3P_dh_N PF01210.18 EWM24210.1 - 4e-43 146.8 0.0 6.5e-43 146.1 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EWM24210.1 - 7.3e-41 139.3 0.2 1.2e-40 138.6 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 EWM24210.1 - 3.5e-08 33.7 0.0 1.5e-07 31.7 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 EWM24210.1 - 1.1e-07 31.3 0.0 2.5e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EWM24210.1 - 0.003 17.2 0.0 0.008 15.8 0.0 1.7 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EWM24210.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.22 EWM24210.1 - 0.025 14.9 1.3 0.065 13.6 0.1 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase PDH PF02153.12 EWM24210.1 - 0.044 12.6 0.0 0.072 11.9 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase TrkA_N PF02254.13 EWM24210.1 - 0.065 13.2 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Bud13 PF09736.4 EWM24211.1 - 1.9e-39 135.2 8.8 1.9e-39 135.2 6.1 1.5 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex Bud13 PF09736.4 EWM24212.1 - 1.9e-39 135.2 8.8 1.9e-39 135.2 6.1 1.5 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex CBS PF00571.23 EWM24213.1 - 1.4e-27 95.2 4.5 8.5e-07 28.6 0.0 4.3 4 0 0 4 4 4 4 CBS domain ABC_tran PF00005.22 EWM24214.1 - 5.5e-47 159.5 0.0 2.1e-22 79.9 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 EWM24214.1 - 4.3e-22 77.7 4.2 4.3e-22 77.7 2.9 2.7 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.1 EWM24214.1 - 1.6e-20 74.2 0.0 5.8e-05 23.1 0.0 4.2 3 1 1 4 4 4 4 AAA domain AAA_17 PF13207.1 EWM24214.1 - 7.4e-10 39.7 0.9 0.00017 22.3 0.0 3.2 3 2 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EWM24214.1 - 5.2e-09 35.5 0.1 0.00024 20.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EWM24214.1 - 1.2e-08 34.4 0.7 0.17 11.1 0.1 3.7 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EWM24214.1 - 2.9e-08 34.2 3.6 0.00083 19.7 0.0 3.8 4 0 0 4 4 4 2 AAA domain SbcCD_C PF13558.1 EWM24214.1 - 5.5e-06 26.2 0.1 0.016 15.0 0.0 3.0 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 EWM24214.1 - 6.6e-06 26.3 0.1 0.0055 16.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EWM24214.1 - 2.4e-05 23.5 0.0 0.037 13.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 EWM24214.1 - 4.1e-05 22.8 0.1 5.5 5.9 0.0 4.2 4 2 0 4 4 4 0 AAA ATPase domain AAA_33 PF13671.1 EWM24214.1 - 0.00029 20.7 0.0 0.43 10.4 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EWM24214.1 - 0.00032 20.9 0.0 0.63 10.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EWM24214.1 - 0.00077 19.3 0.0 0.4 10.6 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_25 PF13481.1 EWM24214.1 - 0.0019 17.5 0.0 0.93 8.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain Miro PF08477.8 EWM24214.1 - 0.0022 18.4 0.0 0.44 11.0 0.0 3.3 3 0 0 3 3 3 1 Miro-like protein AAA_16 PF13191.1 EWM24214.1 - 0.0027 17.7 0.4 0.37 10.7 0.0 2.7 2 2 0 2 2 2 1 AAA ATPase domain MobB PF03205.9 EWM24214.1 - 0.0031 17.2 0.4 0.39 10.4 0.0 2.9 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 EWM24214.1 - 0.0038 17.4 0.0 0.87 9.7 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EWM24214.1 - 0.0083 15.6 7.8 0.21 10.9 0.0 3.7 3 1 1 4 4 4 1 AAA-like domain Dynamin_N PF00350.18 EWM24214.1 - 0.0099 15.7 0.1 3.7 7.3 0.0 3.2 2 1 1 3 3 2 1 Dynamin family DUF87 PF01935.12 EWM24214.1 - 0.012 15.4 6.0 1.1 9.0 0.1 3.8 3 1 1 4 4 4 0 Domain of unknown function DUF87 AAA_5 PF07728.9 EWM24214.1 - 0.017 14.8 0.0 1.1 9.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 EWM24214.1 - 0.019 14.5 0.3 0.35 10.5 0.0 2.5 2 0 0 2 2 2 0 NACHT domain MutS_V PF00488.16 EWM24214.1 - 0.02 14.2 0.0 0.55 9.5 0.0 2.3 2 0 0 2 2 2 0 MutS domain V AAA_30 PF13604.1 EWM24214.1 - 0.021 14.4 1.5 3.1 7.3 0.0 3.4 3 1 0 3 3 3 0 AAA domain AAA_28 PF13521.1 EWM24214.1 - 0.022 14.7 0.6 2.4 8.0 0.0 2.8 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EWM24214.1 - 0.027 14.6 0.0 3 8.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_13 PF13166.1 EWM24214.1 - 0.035 12.5 3.5 4.5 5.6 0.0 3.7 4 0 0 4 4 4 0 AAA domain AAA_14 PF13173.1 EWM24214.1 - 0.048 13.5 0.0 4.5 7.1 0.0 3.3 4 0 0 4 4 3 0 AAA domain G-alpha PF00503.15 EWM24214.1 - 0.062 11.9 0.3 7.2 5.1 0.3 2.6 2 1 0 2 2 2 0 G-protein alpha subunit ArgK PF03308.11 EWM24214.1 - 0.066 11.9 2.7 13 4.4 0.0 3.3 3 0 0 3 3 3 0 ArgK protein CR6_interact PF10147.4 EWM24214.1 - 0.49 9.6 8.2 1.3 8.2 0.8 3.1 3 0 0 3 3 3 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Adaptin_N PF01602.15 EWM24216.1 - 5e-96 322.1 0.0 6.3e-96 321.7 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EWM24216.1 - 1.7e-12 47.4 0.3 9.1e-05 22.6 0.0 5.0 2 2 2 4 4 4 2 HEAT repeats Cnd1 PF12717.2 EWM24216.1 - 9.8e-12 45.0 0.0 6.6e-10 39.1 0.0 3.3 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.5 EWM24216.1 - 1.2e-11 44.5 0.0 2.3e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT PF02985.17 EWM24216.1 - 3.3e-06 26.7 3.0 0.22 11.6 0.0 5.1 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 EWM24216.1 - 0.0017 18.8 1.8 8.7 6.9 0.1 5.0 5 1 1 6 6 6 1 HEAT-like repeat DUF2435 PF10363.4 EWM24216.1 - 0.0028 17.5 0.0 0.22 11.4 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) Arm PF00514.18 EWM24216.1 - 0.043 13.6 0.1 2.7 7.9 0.0 3.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Pro_isomerase PF00160.16 EWM24217.1 - 2.3e-45 154.5 0.0 3.8e-45 153.8 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PDZ PF00595.19 EWM24217.1 - 1.9e-10 40.8 0.2 2.9e-10 40.1 0.1 1.3 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EWM24217.1 - 3.7e-07 29.9 0.0 6.5e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 PDZ domain AA_permease_2 PF13520.1 EWM24218.1 - 2.5e-30 105.3 28.3 3.1e-30 105.0 19.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EWM24218.1 - 1.2e-17 63.4 22.9 1.7e-17 62.9 15.9 1.2 1 0 0 1 1 1 1 Amino acid permease Aminotran_1_2 PF00155.16 EWM24220.1 - 1.5e-40 139.3 0.0 6e-40 137.3 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EWM24220.1 - 0.025 13.7 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase DnaJ PF00226.26 EWM24221.1 - 1.4e-25 88.7 0.4 2.3e-25 88.1 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EWM24221.1 - 7.5e-19 67.4 0.2 8.7e-17 60.8 0.0 2.8 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EWM24221.1 - 2.4e-13 49.9 18.6 4.5e-13 49.0 12.9 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EWM24221.1 - 1.7 8.3 9.3 2.4 7.9 1.4 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family GFO_IDH_MocA PF01408.17 EWM24222.1 - 2.2e-27 95.9 0.4 1.3e-26 93.4 0.2 2.3 3 0 0 3 3 3 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EWM24222.1 - 4.1e-11 42.6 0.0 6.9e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain CoA_binding PF02629.14 EWM24222.1 - 0.0009 19.7 0.5 0.0023 18.4 0.3 1.6 1 0 0 1 1 1 1 CoA binding domain 2-Hacid_dh_C PF02826.14 EWM24222.1 - 0.0013 17.9 0.1 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EWM24222.1 - 0.0052 17.1 0.3 0.014 15.8 0.1 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 EWM24222.1 - 0.0069 16.6 0.1 0.019 15.2 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EWM24222.1 - 0.0084 16.0 0.4 0.11 12.4 0.1 2.4 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_2 PF03446.10 EWM24222.1 - 0.028 14.2 0.1 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Redoxin PF08534.5 EWM24222.1 - 0.075 12.5 0.1 0.17 11.3 0.0 1.6 2 0 0 2 2 2 0 Redoxin Gp_dh_N PF00044.19 EWM24222.1 - 0.1 12.5 2.2 0.9 9.4 1.0 2.5 1 1 2 3 3 3 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Aldo_ket_red PF00248.16 EWM24223.1 - 6.7e-25 87.4 0.0 1.5e-22 79.7 0.0 2.3 2 0 0 2 2 2 2 Aldo/keto reductase family ThuA PF06283.6 EWM24223.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Trehalose utilisation Lipase_3 PF01764.20 EWM24225.1 - 3.9e-10 39.5 0.0 1.1e-09 38.0 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) MTHFR PF02219.12 EWM24226.1 - 9.4e-94 313.6 0.0 5.3e-93 311.2 0.0 1.8 1 1 0 1 1 1 1 Methylenetetrahydrofolate reductase HEAT_2 PF13646.1 EWM24228.1 - 4.1e-17 62.2 1.0 8.2e-09 35.6 0.0 3.5 2 2 1 3 3 3 3 HEAT repeats HEAT PF02985.17 EWM24228.1 - 2.9e-10 39.3 6.6 0.73 10.0 0.0 6.9 7 0 0 7 7 7 5 HEAT repeat Adaptin_N PF01602.15 EWM24228.1 - 0.00068 18.0 0.4 0.2 9.9 0.0 2.2 2 0 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.2 EWM24228.1 - 0.0017 18.2 1.4 4.3 7.1 0.0 4.4 3 2 2 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 EWM24228.1 - 0.0084 16.5 11.5 2.1 8.9 0.0 5.6 4 1 2 6 6 6 1 HEAT-like repeat Trypan_PARP PF05887.6 EWM24229.1 - 1e-13 51.3 154.7 2.3e-09 37.2 48.8 2.2 1 1 1 2 2 2 2 Procyclic acidic repetitive protein (PARP) Mannosyl_trans PF05007.8 EWM24230.1 - 4.1e-73 246.2 4.4 6e-73 245.6 3.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 EWM24230.1 - 2.9e-16 59.3 8.8 3.5e-16 59.0 5.7 1.6 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 EWM24230.1 - 4.4e-08 32.9 14.4 4.4e-08 32.9 10.0 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF2029) 5_3_exonuc_N PF02739.11 EWM24231.1 - 9.9e-42 142.1 0.0 1.5e-41 141.6 0.0 1.2 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.15 EWM24231.1 - 6.2e-22 77.7 0.0 1.3e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold DNA_pol_A PF00476.15 EWM24231.1 - 0.00057 18.6 0.0 0.00092 17.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A HHH PF00633.18 EWM24231.1 - 0.00065 19.2 0.2 0.031 13.9 0.1 2.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_2 PF12826.2 EWM24231.1 - 0.00076 19.3 0.0 0.0024 17.7 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 EWM24231.1 - 0.0014 18.7 0.0 0.0038 17.3 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain GAF_2 PF13185.1 EWM24232.1 - 0.00018 22.0 0.0 0.0016 18.9 0.0 2.4 2 0 0 2 2 2 1 GAF domain Tim44 PF04280.10 EWM24233.1 - 2.4e-26 92.4 0.0 1e-25 90.4 0.0 2.0 2 0 0 2 2 2 1 Tim44-like domain Macoilin PF09726.4 EWM24233.1 - 0.054 11.7 13.9 0.071 11.3 9.6 1.2 1 0 0 1 1 1 0 Transmembrane protein Flu_NS2 PF00601.14 EWM24233.1 - 0.089 13.0 1.8 0.27 11.4 1.2 1.8 1 0 0 1 1 1 0 Influenza non-structural protein (NS2) GLE1 PF07817.8 EWM24233.1 - 0.19 10.6 2.6 0.34 9.7 1.8 1.3 1 0 0 1 1 1 0 GLE1-like protein DUF2935 PF11155.3 EWM24233.1 - 0.25 11.4 1.5 0.84 9.7 1.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) PPR_2 PF13041.1 EWM24234.1 - 5.3e-54 179.9 0.3 1.3e-09 37.8 0.0 11.3 2 1 10 12 12 12 11 PPR repeat family PPR PF01535.15 EWM24234.1 - 9.6e-45 147.4 13.2 0.00017 21.3 0.1 12.0 12 0 0 12 12 12 9 PPR repeat PPR_3 PF13812.1 EWM24234.1 - 4.1e-43 142.0 13.3 0.00013 21.9 0.0 12.5 12 0 0 12 12 12 8 Pentatricopeptide repeat domain PPR_1 PF12854.2 EWM24234.1 - 3.3e-33 112.8 0.0 8.6e-07 28.3 0.0 9.1 9 0 0 9 9 9 7 PPR repeat ECSIT PF06239.6 EWM24234.1 - 1e-06 27.7 0.1 0.52 9.1 0.0 6.1 4 2 3 7 7 7 1 Evolutionarily conserved signalling intermediate in Toll pathway TPR_12 PF13424.1 EWM24234.1 - 1.2e-05 25.1 0.5 0.35 10.8 0.0 4.7 3 1 3 6 6 6 3 Tetratricopeptide repeat PDZ_2 PF13180.1 EWM24234.1 - 0.00013 21.7 0.0 0.11 12.3 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.19 EWM24234.1 - 0.0028 17.7 0.0 0.032 14.4 0.0 2.3 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) TPR_11 PF13414.1 EWM24234.1 - 0.0079 15.8 0.5 1.6 8.4 0.0 3.2 4 0 0 4 4 4 1 TPR repeat TPR_16 PF13432.1 EWM24234.1 - 0.0092 16.6 9.8 14 6.5 0.0 6.0 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 EWM24234.1 - 0.015 15.9 13.9 3.9 8.3 0.1 7.3 7 3 3 10 10 6 0 Tetratricopeptide repeat MRP-S27 PF10037.4 EWM24234.1 - 0.043 12.7 0.0 3.9 6.2 0.0 3.1 2 1 1 3 3 3 0 Mitochondrial 28S ribosomal protein S27 ATP13 PF12921.2 EWM24234.1 - 0.044 13.1 0.0 3.4 7.0 0.0 3.5 3 2 1 4 4 4 0 Mitochondrial ATPase expression TPR_7 PF13176.1 EWM24234.1 - 0.045 13.5 0.0 34 4.5 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EWM24234.1 - 0.071 13.0 0.1 0.071 13.0 0.0 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat Clathrin PF00637.15 EWM24234.1 - 0.12 11.9 0.0 1 8.9 0.0 2.5 2 0 0 2 2 2 0 Region in Clathrin and VPS TPR_2 PF07719.12 EWM24234.1 - 0.14 12.1 0.8 2.2 8.4 0.2 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EWM24234.1 - 5.4 7.7 8.3 9.4 6.9 0.0 5.0 6 0 0 6 6 5 0 Tetratricopeptide repeat cobW PF02492.14 EWM24235.1 - 2.9e-35 121.3 0.0 3.8e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EWM24235.1 - 6.1e-05 21.9 0.2 0.13 11.0 0.2 2.1 2 0 0 2 2 2 2 ArgK protein AAA_17 PF13207.1 EWM24235.1 - 0.017 15.9 0.1 0.041 14.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 EWM24235.1 - 0.025 13.4 0.0 0.038 12.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein MMR_HSR1 PF01926.18 EWM24235.1 - 0.028 14.3 0.0 0.07 13.0 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 EWM24235.1 - 0.054 13.7 0.6 0.49 10.6 0.0 2.1 2 0 0 2 2 2 0 ABC transporter KAP_NTPase PF07693.9 EWM24235.1 - 0.082 11.8 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain CbiA PF01656.18 EWM24235.1 - 0.1 11.9 0.2 0.25 10.7 0.1 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.7 EWM24235.1 - 0.16 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 EWM24235.1 - 0.22 11.8 1.1 0.26 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EWM24236.1 - 2.4e-35 121.5 0.0 3.2e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EWM24236.1 - 4.9e-05 22.2 0.2 0.11 11.2 0.2 2.1 2 0 0 2 2 2 2 ArgK protein AAA_17 PF13207.1 EWM24236.1 - 0.015 16.1 0.1 0.037 14.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 EWM24236.1 - 0.022 13.6 0.0 0.034 13.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein MMR_HSR1 PF01926.18 EWM24236.1 - 0.024 14.5 0.0 0.058 13.3 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase KAP_NTPase PF07693.9 EWM24236.1 - 0.076 11.9 0.0 0.094 11.6 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain CbiA PF01656.18 EWM24236.1 - 0.085 12.2 0.1 0.2 11.0 0.1 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.22 EWM24236.1 - 0.09 13.0 0.1 0.44 10.8 0.0 1.9 2 0 0 2 2 2 0 ABC transporter MobB PF03205.9 EWM24236.1 - 0.11 12.1 0.0 0.45 10.2 0.0 2.1 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EWM24236.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 EWM24236.1 - 0.23 11.7 1.3 0.24 11.7 0.0 1.9 2 1 0 2 2 2 0 AAA domain FAD_binding_3 PF01494.14 EWM24238.1 - 1.7e-23 83.2 0.3 1.3e-22 80.3 0.2 2.1 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EWM24238.1 - 2.8e-05 23.1 0.0 4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EWM24238.1 - 7.4e-05 21.8 0.2 0.00012 21.1 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EWM24238.1 - 0.00021 21.2 0.4 0.0006 19.7 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EWM24238.1 - 0.00035 19.5 0.6 0.00084 18.2 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EWM24238.1 - 0.0015 18.6 0.0 0.0035 17.4 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EWM24238.1 - 0.0019 18.1 0.0 0.0037 17.1 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EWM24238.1 - 0.011 14.9 0.1 0.017 14.2 0.1 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 EWM24238.1 - 0.033 14.6 0.1 0.033 14.6 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EWM24238.1 - 0.079 12.0 0.1 0.094 11.7 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase SPRY PF00622.23 EWM24239.1 - 1.1e-14 54.6 0.1 3.5e-09 36.8 0.2 2.7 2 0 0 2 2 2 2 SPRY domain DUF1995 PF09353.5 EWM24240.1 - 2.8e-06 27.1 0.1 0.00059 19.5 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1995) HHH_5 PF14520.1 EWM24241.1 - 0.00021 21.3 0.0 0.00044 20.3 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 EWM24241.1 - 0.03 13.8 0.0 0.075 12.5 0.0 1.6 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda Transcrip_reg PF01709.15 EWM24242.1 - 1.2e-65 220.8 3.7 1.4e-65 220.6 2.6 1.0 1 0 0 1 1 1 1 Transcriptional regulator Rad21_Rec8_N PF04825.8 EWM24243.1 - 1.6e-41 140.7 0.0 1.8e-41 140.5 0.0 1.0 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein WD40 PF00400.27 EWM24244.1 - 4.6e-71 232.3 8.8 6.9e-11 41.5 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EWM24244.1 - 3.7e-06 25.3 2.4 0.095 10.8 0.0 3.5 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EWM24244.1 - 0.0002 20.2 0.0 0.48 9.1 0.0 3.3 2 1 1 3 3 3 3 Nup133 N terminal like DUF3312 PF11768.3 EWM24244.1 - 0.0003 19.1 0.0 0.00058 18.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) Cons_hypoth95 PF03602.10 EWM24245.1 - 6.3e-38 129.9 0.0 8.3e-38 129.5 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_26 PF13659.1 EWM24245.1 - 2.1e-07 30.9 0.0 3.6e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM24245.1 - 0.0007 20.1 0.0 0.0015 19.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM24245.1 - 0.0031 17.1 0.0 0.0045 16.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EWM24245.1 - 0.005 16.2 0.0 0.0076 15.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain MethyltransfD12 PF02086.10 EWM24245.1 - 0.045 13.2 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Methyltrans_SAM PF10672.4 EWM24245.1 - 0.071 11.9 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase TFIIE_alpha PF02002.12 EWM24246.1 - 3.4e-17 61.8 2.1 6.1e-17 61.0 1.5 1.3 1 0 0 1 1 1 1 TFIIE alpha subunit RNase_H_2 PF13482.1 EWM24246.1 - 0.00052 19.8 0.0 0.0013 18.5 0.0 1.6 1 1 0 1 1 1 1 RNase_H superfamily Arc_trans_TRASH PF08394.5 EWM24246.1 - 0.015 15.4 1.4 0.039 14.1 1.0 1.6 1 0 0 1 1 1 0 Archaeal TRASH domain Methyltransf_10 PF05971.7 EWM24247.1 - 3e-76 256.4 0.0 7.4e-44 150.0 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF890) PrmA PF06325.8 EWM24247.1 - 9.6e-07 28.2 0.0 1.5e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EWM24247.1 - 1.8e-06 27.4 0.0 0.066 12.5 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_26 PF13659.1 EWM24247.1 - 1.5e-05 24.9 0.0 3.6e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM24247.1 - 0.00026 21.5 0.0 0.00054 20.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM24247.1 - 0.0035 17.7 0.0 0.008 16.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EWM24247.1 - 0.0071 15.9 0.0 0.6 9.6 0.0 2.3 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.7 EWM24247.1 - 0.014 15.8 0.0 0.033 14.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EWM24247.1 - 0.018 14.6 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RhoGEF PF00621.15 EWM24248.1 - 4.1e-45 153.8 0.0 6e-45 153.3 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PDZ_2 PF13180.1 EWM24248.1 - 2.7e-06 27.1 0.0 7.4e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PH PF00169.24 EWM24248.1 - 4.6e-05 23.5 0.0 9.6e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 PH domain PDZ PF00595.19 EWM24248.1 - 0.025 14.7 0.0 0.054 13.6 0.0 1.5 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) Tricorn_PDZ PF14685.1 EWM24248.1 - 0.028 14.2 0.1 0.098 12.4 0.0 1.9 2 0 0 2 2 2 0 Tricorn protease PDZ domain DUF1408 PF07193.6 EWM24248.1 - 0.19 11.2 0.1 0.47 10.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1408) Med22 PF06179.7 EWM24249.1 - 2.5e-06 27.4 2.3 3.1e-06 27.1 1.6 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex IgG_binding_B PF01378.12 EWM24249.1 - 0.04 13.7 0.1 0.54 10.1 0.0 2.3 2 0 0 2 2 2 0 B domain CENP-R PF06729.7 EWM24249.1 - 0.044 13.4 0.5 0.053 13.1 0.3 1.1 1 0 0 1 1 1 0 Kinetochore component, CENP-R MIS13 PF08202.6 EWM24249.1 - 0.086 11.8 0.6 0.13 11.2 0.4 1.4 1 1 0 1 1 1 0 Mis12-Mtw1 protein family Prefoldin_2 PF01920.15 EWM24249.1 - 0.11 12.2 0.7 0.37 10.5 0.0 1.8 1 1 1 2 2 2 0 Prefoldin subunit SUZ PF12752.2 EWM24250.1 - 4.6e-10 39.8 2.3 4.6e-10 39.8 1.6 2.3 2 0 0 2 2 2 1 SUZ domain R3H PF01424.17 EWM24250.1 - 1.8e-05 24.3 0.0 3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 R3H domain Ribosomal_L22 PF00237.14 EWM24251.1 - 1.2e-32 111.9 0.0 1.5e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e SATase_N PF06426.9 EWM24252.1 - 1.7e-17 63.6 0.1 2.6e-17 62.9 0.1 1.3 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep PF00132.19 EWM24252.1 - 7.5e-09 34.7 8.1 5.6e-06 25.6 0.9 2.4 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EWM24252.1 - 0.029 13.9 13.6 0.054 13.0 3.7 2.6 2 1 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Peptidase_C97 PF05903.9 EWM24253.1 - 0.0029 17.3 0.2 0.0057 16.4 0.1 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain zf-HC5HC2H_2 PF13832.1 EWM24254.1 - 1.4e-55 186.0 37.9 1.8e-23 82.6 2.0 6.7 7 0 0 7 7 7 4 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EWM24254.1 - 9.3e-29 99.4 20.9 2.1e-15 56.6 1.1 7.2 6 2 2 8 8 8 3 PHD-like zinc-binding domain PHD_2 PF13831.1 EWM24254.1 - 2.2e-21 74.8 46.2 8.3e-11 41.0 3.2 6.9 6 0 0 6 6 6 3 PHD-finger PHD PF00628.24 EWM24254.1 - 8.6e-19 66.9 95.7 1.1e-08 34.6 3.3 8.7 11 0 0 11 11 11 6 PHD-finger Bromodomain PF00439.20 EWM24254.1 - 4.1e-17 61.8 0.0 7.9e-17 60.9 0.0 1.4 1 0 0 1 1 1 1 Bromodomain C1_1 PF00130.17 EWM24254.1 - 0.0024 17.5 1.7 0.0024 17.5 1.2 8.7 9 0 0 9 9 9 3 Phorbol esters/diacylglycerol binding domain (C1 domain) NAD_binding_10 PF13460.1 EWM24255.1 - 3.1e-30 105.5 0.1 3.8e-30 105.2 0.1 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EWM24255.1 - 8.8e-10 38.2 0.2 1.3e-09 37.6 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EWM24255.1 - 6e-08 32.4 0.0 8.2e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EWM24255.1 - 2.9e-07 29.4 0.0 4.1e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EWM24255.1 - 0.00054 19.9 0.8 0.0013 18.6 0.5 1.7 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EWM24255.1 - 0.0014 17.5 0.2 0.16 10.8 0.1 2.3 2 0 0 2 2 2 1 Male sterility protein KR PF08659.5 EWM24255.1 - 0.0091 15.6 0.5 0.02 14.5 0.3 1.6 1 1 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EWM24255.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EWM24255.1 - 0.012 15.8 0.2 0.69 10.1 0.2 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding DapB_N PF01113.15 EWM24255.1 - 0.017 15.0 2.3 0.041 13.8 0.9 2.2 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EWM24255.1 - 0.028 14.7 0.2 0.075 13.3 0.1 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain AAA_19 PF13245.1 EWM24255.1 - 0.053 13.2 0.0 0.3 10.8 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain TrkA_N PF02254.13 EWM24255.1 - 0.12 12.3 0.4 0.47 10.4 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain DHquinase_I PF01487.10 EWM24256.1 - 1.6e-41 142.3 0.0 2.4e-41 141.8 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 EWM24256.1 - 4.6e-23 81.0 0.0 1.3e-22 79.5 0.0 1.8 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EWM24256.1 - 1.6e-08 34.7 0.0 4e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ETF PF01012.16 EWM24256.1 - 0.0058 16.3 0.3 0.062 13.0 0.0 2.6 2 1 0 2 2 2 1 Electron transfer flavoprotein domain NAD_binding_8 PF13450.1 EWM24256.1 - 0.027 14.4 0.2 0.88 9.6 0.1 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF2092 PF09865.4 EWM24256.1 - 0.13 11.3 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2092) Rad51 PF08423.6 EWM24257.1 - 1.5e-52 178.0 0.4 2.3e-52 177.4 0.3 1.2 1 0 0 1 1 1 1 Rad51 HHH_5 PF14520.1 EWM24257.1 - 2.7e-09 37.0 1.5 7.8e-09 35.5 0.3 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain AAA_25 PF13481.1 EWM24257.1 - 5.2e-06 25.9 0.0 7e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EWM24257.1 - 1.9e-05 23.8 0.1 3e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 KaiC RecA PF00154.16 EWM24257.1 - 2.3e-05 23.6 0.1 3.2e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein MFS_1 PF07690.11 EWM24258.1 - 8.9e-26 90.4 19.9 6.7e-25 87.5 13.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EWM24258.1 - 6.1e-06 25.0 2.2 6.1e-06 25.0 1.5 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.2 EWM24258.1 - 0.004 16.9 3.9 0.0092 15.7 0.3 3.0 3 0 0 3 3 3 1 MFS_1 like family OATP PF03137.15 EWM24258.1 - 0.026 12.6 0.2 0.063 11.3 0.0 1.7 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF1228 PF06779.9 EWM24258.1 - 3 7.9 8.9 1 9.4 1.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) ELO PF01151.13 EWM24259.1 - 2.3e-42 145.0 15.9 3.5e-42 144.4 11.1 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family VPS9 PF02204.13 EWM24260.1 - 1.1e-09 38.2 0.0 1.9e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain C1_1 PF00130.17 EWM24260.1 - 1.4e-06 27.8 3.8 3e-06 26.8 2.6 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE PF01363.16 EWM24260.1 - 1.1 9.1 6.6 2 8.3 3.8 2.1 1 1 0 1 1 1 0 FYVE zinc finger DUF4460 PF14687.1 EWM24261.1 - 4.2e-11 42.6 0.9 1.7e-10 40.6 0.1 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4460) Cohesin_load PF10345.4 EWM24261.1 - 0.068 11.3 1.6 0.14 10.3 0.1 1.8 2 0 0 2 2 2 0 Cohesin loading factor DUF2935 PF11155.3 EWM24261.1 - 0.082 12.9 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) PseudoU_synth_2 PF00849.17 EWM24262.1 - 1.6e-24 86.6 0.0 2.2e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase PPR_2 PF13041.1 EWM24264.1 - 1e-23 83.0 0.0 1.1e-06 28.5 0.0 6.8 6 1 1 7 7 7 6 PPR repeat family PPR PF01535.15 EWM24264.1 - 1.1e-13 50.1 1.3 0.0036 17.1 0.0 5.9 7 0 0 7 7 7 3 PPR repeat PPR_1 PF12854.2 EWM24264.1 - 3.6e-13 48.7 0.0 0.0022 17.4 0.0 6.1 6 0 0 6 6 6 4 PPR repeat PPR_3 PF13812.1 EWM24264.1 - 2e-09 36.9 7.0 0.1 12.9 0.0 5.5 6 0 0 6 6 6 3 Pentatricopeptide repeat domain TPR_16 PF13432.1 EWM24264.1 - 0.02 15.5 1.5 0.02 15.5 1.1 3.9 3 2 1 4 4 4 0 Tetratricopeptide repeat PqiA PF04403.8 EWM24265.1 - 1e-12 47.9 18.0 1.5e-11 44.1 1.5 2.6 3 0 0 3 3 3 2 Paraquat-inducible protein A 2OG-FeII_Oxy_3 PF13640.1 EWM24266.1 - 5.3e-09 36.4 0.0 9.6e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EWM24266.1 - 1.1e-07 32.0 0.0 2.4e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Nop52 PF05997.7 EWM24267.1 - 2.7e-56 190.4 0.0 3.8e-56 189.9 0.0 1.2 1 0 0 1 1 1 1 Nucleolar protein,Nop52 CD24 PF14984.1 EWM24267.1 - 0.22 11.3 3.0 0.6 9.9 2.1 1.7 1 0 0 1 1 1 0 CD24 protein G-patch PF01585.18 EWM24268.1 - 3.6e-14 52.2 0.8 7.9e-14 51.1 0.5 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EWM24268.1 - 2.8e-06 27.0 0.5 6.2e-06 25.9 0.4 1.6 1 0 0 1 1 1 1 DExH-box splicing factor binding site Abi PF02517.11 EWM24269.1 - 3.6e-15 55.8 1.1 3.6e-15 55.8 0.8 2.2 3 0 0 3 3 3 1 CAAX protease self-immunity DUF3464 PF11947.3 EWM24269.1 - 7.3 6.0 6.7 3.5 7.0 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) Sec1 PF00995.18 EWM24270.1 - 6.3e-122 408.0 0.0 5.4e-121 404.9 0.0 1.9 1 1 0 1 1 1 1 Sec1 family OTCace_N PF02729.16 EWM24271.1 - 5.5e-40 136.3 0.0 2.6e-39 134.1 0.0 2.0 2 1 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 EWM24271.1 - 5.7e-38 130.2 0.0 9.9e-38 129.4 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain LRR_6 PF13516.1 EWM24272.1 - 2.6e-23 79.4 20.1 0.033 14.2 0.0 12.4 13 0 0 13 13 13 6 Leucine Rich repeat LRR_4 PF12799.2 EWM24272.1 - 8.2e-14 50.8 2.5 0.00047 19.6 0.0 7.1 6 1 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EWM24272.1 - 6.3e-06 25.5 10.6 52 4.7 0.0 9.7 11 0 0 11 11 11 0 Leucine rich repeat LRR_1 PF00560.28 EWM24272.1 - 0.0001 21.8 13.0 18 5.8 0.0 8.6 10 0 0 10 10 10 1 Leucine Rich Repeat LRR_8 PF13855.1 EWM24272.1 - 0.00039 20.1 17.3 0.16 11.7 0.2 7.7 5 3 1 7 7 7 3 Leucine rich repeat DUF1214 PF06742.6 EWM24273.1 - 9.6e-06 26.0 7.2 3.3e-05 24.2 0.0 3.2 4 0 0 4 4 4 2 Protein of unknown function (DUF1214) SHS2_Rpb7-N PF03876.12 EWM24275.1 - 2.8e-10 40.1 0.0 8.9e-10 38.5 0.0 1.8 2 1 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EWM24275.1 - 3.7e-07 30.1 0.0 7.1e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 EWM24275.1 - 1e-06 28.9 0.0 1.9e-06 28.0 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 S1 PF00575.18 EWM24276.1 - 2.3e-07 30.8 0.0 4.3e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 EWM24276.1 - 6e-07 29.6 0.0 1.4e-06 28.4 0.0 1.6 1 1 1 2 2 2 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EWM24276.1 - 6.6e-05 22.9 0.1 0.00022 21.2 0.0 1.9 2 1 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 F-box-like PF12937.2 EWM24277.1 - 5.1e-08 32.5 0.5 8.4e-08 31.8 0.3 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EWM24277.1 - 5.2e-06 25.9 0.1 1e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 F-box domain Band_7 PF01145.20 EWM24278.1 - 1.2e-20 74.1 7.2 7.1e-20 71.6 5.0 1.9 1 1 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.3 EWM24278.1 - 0.12 12.4 1.2 0.22 11.5 0.8 1.4 1 0 0 1 1 1 0 Mediator complex subunit 2 PPR_2 PF13041.1 EWM24279.1 - 1.4e-44 149.7 7.2 5.2e-10 39.1 0.0 10.9 4 3 8 12 12 12 8 PPR repeat family PPR_3 PF13812.1 EWM24279.1 - 1.6e-41 137.0 21.5 4e-06 26.6 0.0 13.4 13 0 0 13 13 13 7 Pentatricopeptide repeat domain PPR PF01535.15 EWM24279.1 - 5.3e-40 132.6 23.8 1.1e-06 28.2 0.0 11.8 13 0 0 13 13 13 7 PPR repeat PPR_1 PF12854.2 EWM24279.1 - 8e-23 79.6 0.0 3e-05 23.3 0.0 7.3 7 0 0 7 7 6 4 PPR repeat TPR_15 PF13429.1 EWM24279.1 - 8.4e-06 25.0 1.4 0.24 10.3 0.0 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EWM24279.1 - 6.1e-05 22.5 2.7 3.5 7.6 0.1 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EWM24279.1 - 0.00015 22.0 0.6 0.95 9.8 0.1 4.9 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 EWM24279.1 - 0.00017 22.1 5.6 0.045 14.4 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat Clathrin PF00637.15 EWM24279.1 - 0.0048 16.4 0.0 8.6 5.9 0.0 4.1 4 0 0 4 4 4 1 Region in Clathrin and VPS Smr PF01713.16 EWM24279.1 - 0.0052 16.9 0.0 0.086 13.0 0.0 2.8 1 1 0 1 1 1 1 Smr domain TPR_14 PF13428.1 EWM24279.1 - 0.024 15.2 28.7 4.9 8.0 0.0 10.1 9 2 3 12 12 10 0 Tetratricopeptide repeat TPR_2 PF07719.12 EWM24279.1 - 0.068 13.1 9.4 15 5.8 0.0 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 EWM24279.1 - 8.3 7.1 16.7 31 5.3 0.0 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Voltage_CLC PF00654.15 EWM24280.1 - 1.4e-77 261.1 18.6 1.4e-77 261.1 12.9 1.4 1 1 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.23 EWM24280.1 - 6.8e-11 41.7 0.0 1e-05 25.2 0.0 2.6 2 0 0 2 2 2 2 CBS domain Claudin_2 PF13903.1 EWM24280.1 - 0.003 17.2 1.1 0.003 17.2 0.7 2.9 2 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction UCR_Fe-S_N PF10399.4 EWM24280.1 - 0.053 12.7 0.7 0.17 11.0 0.5 1.9 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal CBS PF00571.23 EWM24281.1 - 2.9e-30 103.7 14.3 8.3e-10 38.2 0.7 4.6 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 EWM24281.1 - 0.0011 18.5 0.0 0.0047 16.5 0.0 2.2 1 0 0 1 1 1 1 PB1 domain TatD_DNase PF01026.16 EWM24282.1 - 1.9e-58 197.6 0.0 2.4e-58 197.3 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.9 EWM24282.1 - 0.091 12.3 0.1 14 5.1 0.0 2.7 1 1 1 2 2 2 0 Amidohydrolase UPF0118 PF01594.11 EWM24283.1 - 0.063 12.2 0.5 0.067 12.1 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF20 Ribosomal_L35p PF01632.14 EWM24284.1 - 1.3e-11 44.2 1.6 2.2e-11 43.4 1.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L35 CLTH PF10607.4 EWM24287.1 - 3.5e-20 72.1 0.0 6.4e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EWM24287.1 - 8.9e-17 60.5 0.7 2.4e-16 59.1 0.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 EWM24287.1 - 7.3e-05 22.5 0.7 0.00014 21.5 0.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EWM24287.1 - 0.00011 21.8 0.8 0.00021 20.9 0.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EWM24287.1 - 0.0029 17.4 0.7 0.0073 16.1 0.5 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EWM24287.1 - 0.0035 17.3 1.3 0.0081 16.1 0.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EWM24287.1 - 0.007 16.0 0.9 0.013 15.1 0.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF2560 PF10834.3 EWM24287.1 - 0.03 14.2 0.3 3.5 7.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2560) Rtf2 PF04641.7 EWM24287.1 - 0.043 13.0 0.0 0.077 12.1 0.0 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger zf-C3HC4 PF00097.20 EWM24287.1 - 0.14 11.8 0.8 0.32 10.6 0.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DNA_topoisoIV PF00521.15 EWM24288.1 - 1.2e-142 475.7 0.0 1.5e-142 475.4 0.0 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.8 EWM24288.1 - 1.9e-48 161.5 4.6 2e-09 36.5 0.0 6.6 6 0 0 6 6 6 6 DNA gyrase C-terminal domain, beta-propeller Thioredoxin PF00085.15 EWM24289.1 - 8.1e-27 92.9 0.0 1.2e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EWM24289.1 - 6.6e-06 26.2 0.0 3.4e-05 24.0 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 EWM24289.1 - 0.002 17.6 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EWM24289.1 - 0.0054 16.8 0.0 0.015 15.4 0.0 1.7 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_6 PF13848.1 EWM24289.1 - 0.041 13.6 0.0 0.1 12.3 0.0 1.6 2 0 0 2 2 2 0 Thioredoxin-like domain VirB3 PF05101.8 EWM24289.1 - 0.042 13.8 0.6 3.1 7.8 0.1 2.2 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein Thioredoxin_7 PF13899.1 EWM24289.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Helicase_C PF00271.26 EWM24290.1 - 7.4e-14 51.3 0.1 1.1e-12 47.5 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RNase_T PF00929.19 EWM24290.1 - 2.9e-09 37.3 0.0 1.8e-08 34.8 0.0 2.3 1 1 0 1 1 1 1 Exonuclease DEAD PF00270.24 EWM24290.1 - 1.5e-07 31.0 0.0 2.8e-05 23.6 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 EWM24290.1 - 0.008 16.0 0.0 0.023 14.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Antimicrobial12 PF08107.6 EWM24291.1 - 7e-05 22.2 0.1 0.00017 21.0 0.0 1.6 2 0 0 2 2 2 1 Pleurocidin family EXS PF03124.9 EWM24292.1 - 2.6e-70 237.1 14.9 3.4e-70 236.8 10.3 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 EWM24292.1 - 6.4e-27 95.0 0.0 4.3e-25 89.0 0.0 2.1 1 1 0 1 1 1 1 SPX domain FliD_C PF07195.7 EWM24292.1 - 0.0095 15.2 0.1 0.013 14.7 0.1 1.2 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 C-terminus MMR_HSR1_C PF08438.5 EWM24293.1 - 5.3e-26 90.9 0.0 1.1e-25 90.0 0.0 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 EWM24293.1 - 3.7e-16 59.1 0.0 9.6e-16 57.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EWM24293.1 - 3.1e-08 33.0 0.7 1.9e-07 30.4 0.2 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B TGS PF02824.16 EWM24293.1 - 0.078 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 TGS domain Ribosomal_S25 PF03297.10 EWM24294.1 - 2.7e-43 146.2 3.9 3e-43 146.1 2.7 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.1 EWM24294.1 - 0.00021 20.6 0.7 0.00031 20.0 0.5 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 EWM24294.1 - 0.0068 16.0 0.1 0.0091 15.6 0.1 1.2 1 0 0 1 1 1 1 MarR family Fe_dep_repress PF01325.14 EWM24294.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain GntR PF00392.16 EWM24294.1 - 0.021 14.2 0.3 0.062 12.7 0.1 1.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_27 PF13463.1 EWM24294.1 - 0.029 14.6 0.0 0.041 14.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain EAP30 PF04157.11 EWM24294.1 - 0.033 13.3 0.0 0.046 12.8 0.0 1.3 1 1 0 1 1 1 0 EAP30/Vps36 family Rrf2 PF02082.15 EWM24294.1 - 0.075 13.1 0.1 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator TrmB PF01978.14 EWM24294.1 - 0.075 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB PaaX PF07848.7 EWM24294.1 - 0.091 12.7 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 PaaX-like protein MarR PF01047.17 EWM24294.1 - 0.11 12.2 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 MarR family tRNA-synt_2 PF00152.15 EWM24295.1 - 2.1e-68 230.5 0.0 2.7e-68 230.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) GST_C PF00043.20 EWM24295.1 - 3.8e-09 36.4 0.0 8.6e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA_anti-codon PF01336.20 EWM24295.1 - 1.9e-08 34.0 0.0 3.6e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain GST_C_2 PF13410.1 EWM24295.1 - 6.6e-07 29.1 0.1 2e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EWM24295.1 - 2.5e-06 27.8 0.0 8.9e-06 26.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain tRNA-synt_2d PF01409.15 EWM24295.1 - 0.017 14.3 0.0 0.14 11.3 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) CbiQ PF02361.11 EWM24297.1 - 0.17 11.4 3.6 0.19 11.2 2.5 1.1 1 0 0 1 1 1 0 Cobalt transport protein DUF4044 PF13253.1 EWM24297.1 - 0.38 9.9 8.5 0.75 8.9 5.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) OPT PF03169.10 EWM24297.1 - 0.62 8.4 6.4 0.67 8.3 4.4 1.1 1 0 0 1 1 1 0 OPT oligopeptide transporter protein EmrE PF13536.1 EWM24297.1 - 0.66 10.1 7.0 0.79 9.9 4.5 1.4 1 1 0 1 1 1 0 Multidrug resistance efflux transporter SP_C-Propep PF08999.5 EWM24297.1 - 1.1 8.8 4.0 1.4 8.4 2.7 1.3 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Baculo_11_kDa PF06143.6 EWM24297.1 - 7.4 6.0 7.4 11 5.4 5.1 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family Alg14 PF08660.6 EWM24298.1 - 1.9e-57 193.9 0.0 2.8e-57 193.3 0.0 1.3 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Atg14 PF10186.4 EWM24299.1 - 2.3e-12 46.4 0.0 5.2e-12 45.3 0.0 1.4 1 1 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 SlyX PF04102.7 EWM24299.1 - 2 8.8 5.0 7.6 6.9 1.5 2.4 1 1 1 2 2 2 0 SlyX ATP-grasp_2 PF08442.5 EWM24300.1 - 1.3e-64 217.2 0.9 2.1e-64 216.6 0.2 1.7 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 EWM24300.1 - 1.1e-24 86.7 1.8 1.1e-24 86.7 1.3 2.0 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.1 EWM24300.1 - 1.1e-05 24.7 0.4 1.1e-05 24.7 0.2 1.8 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 EWM24300.1 - 5e-05 22.9 1.3 0.011 15.2 0.0 2.6 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Alba PF01918.16 EWM24300.1 - 0.05 13.2 0.4 0.11 12.0 0.3 1.6 1 0 0 1 1 1 0 Alba ATP-grasp_2 PF08442.5 EWM24301.1 - 2.3e-64 216.4 0.3 2.3e-64 216.4 0.2 1.8 3 0 0 3 3 3 1 ATP-grasp domain Ligase_CoA PF00549.14 EWM24301.1 - 1.2e-24 86.6 1.8 1.2e-24 86.6 1.3 2.0 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.1 EWM24301.1 - 1.2e-05 24.6 0.4 1.2e-05 24.6 0.2 2.1 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 EWM24301.1 - 1.7e-05 24.4 2.6 0.012 15.2 0.0 2.6 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Alba PF01918.16 EWM24301.1 - 0.014 14.9 0.7 0.034 13.7 0.5 1.6 1 0 0 1 1 1 0 Alba Las1 PF04031.8 EWM24302.1 - 4.5e-45 153.0 0.1 6.8e-45 152.4 0.0 1.3 1 0 0 1 1 1 1 Las1-like Methyltransf_26 PF13659.1 EWM24303.1 - 1.9e-09 37.5 0.1 3.5e-09 36.7 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM24303.1 - 2.6e-09 37.6 0.1 8.9e-09 35.9 0.1 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM24303.1 - 2.3e-07 30.5 0.0 3.3e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM24303.1 - 8e-06 25.6 0.0 1.1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EWM24303.1 - 8.9e-06 24.8 0.0 1.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase DOT1 PF08123.8 EWM24303.1 - 1e-05 24.9 0.0 1.5e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 CMAS PF02353.15 EWM24303.1 - 1.3e-05 24.4 0.0 1.8e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 EWM24303.1 - 1.4e-05 25.4 0.0 3.1e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM24303.1 - 3.9e-05 24.0 0.0 0.00046 20.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM24303.1 - 4.2e-05 23.8 0.5 0.00035 20.9 0.3 2.2 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EWM24303.1 - 0.00081 18.7 0.0 0.0018 17.6 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain MetW PF07021.7 EWM24303.1 - 0.0025 17.2 0.0 0.0036 16.6 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW UPF0020 PF01170.13 EWM24303.1 - 0.0044 16.6 0.0 0.0069 15.9 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.1 EWM24303.1 - 0.022 14.4 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EWM24303.1 - 0.026 13.6 0.0 0.036 13.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 EWM24303.1 - 0.07 13.1 0.0 0.088 12.7 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Sel1 PF08238.7 EWM24304.1 - 1.2e-38 130.6 34.8 9.8e-06 26.0 0.1 12.3 12 0 0 12 12 12 10 Sel1 repeat Cullin PF00888.17 EWM24305.1 - 4.8e-177 590.0 2.9 5.5e-177 589.8 2.0 1.0 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EWM24305.1 - 1.1e-28 98.8 0.2 3e-28 97.4 0.1 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain AMP-binding PF00501.23 EWM24306.1 - 1.7e-79 267.1 0.0 3.1e-79 266.3 0.0 1.3 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.23 EWM24307.1 - 1.7e-79 267.1 0.0 3.1e-79 266.3 0.0 1.3 1 1 0 1 1 1 1 AMP-binding enzyme tRNA-synt_2 PF00152.15 EWM24309.1 - 3e-75 253.0 0.0 3.8e-75 252.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) WHEP-TRS PF00458.15 EWM24309.1 - 2.2e-12 46.4 2.4 4.3e-12 45.5 1.7 1.5 1 0 0 1 1 1 1 WHEP-TRS domain tRNA_anti-codon PF01336.20 EWM24309.1 - 0.00046 19.9 0.1 0.00081 19.2 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EWM24309.1 - 0.0016 17.6 0.2 0.3 10.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUF4096 PF13340.1 EWM24309.1 - 0.11 12.3 0.2 0.31 10.9 0.0 1.8 2 0 0 2 2 2 0 Putative transposase of IS4/5 family (DUF4096) OTU PF02338.14 EWM24311.1 - 1.5e-16 61.0 0.0 4.8e-16 59.4 0.0 2.0 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EWM24311.1 - 0.018 14.3 0.0 0.17 11.2 0.0 2.4 3 0 0 3 3 3 0 Peptidase C65 Otubain UIM PF02809.15 EWM24311.1 - 1.1 9.0 0.0 0.064 12.8 0.3 5.7 7 0 0 7 7 7 0 Ubiquitin interaction motif CTDII PF01556.13 EWM24312.1 - 2.5e-24 84.9 9.0 9.5e-14 51.0 0.5 3.3 3 0 0 3 3 3 3 DnaJ C terminal domain DnaJ PF00226.26 EWM24312.1 - 5.2e-23 80.5 4.2 1e-22 79.6 2.9 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EWM24312.1 - 4.4e-15 55.4 18.7 9.6e-15 54.3 12.9 1.6 1 0 0 1 1 1 1 DnaJ central domain L_biotic_typeA PF04604.8 EWM24312.1 - 0.13 11.9 0.9 13 5.5 0.2 2.8 2 0 0 2 2 2 0 Type-A lantibiotic UQ_con PF00179.21 EWM24313.1 - 4.1e-35 120.2 0.0 6.2e-35 119.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EWM24313.1 - 0.0018 18.0 0.0 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B Slu7 PF11708.3 EWM24314.1 - 1.2e-64 218.3 24.4 1.2e-64 218.3 16.9 3.1 3 1 0 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 EWM24314.1 - 0.03 14.0 0.8 0.064 12.9 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle Ycf1 PF05758.7 EWM24314.1 - 2.5 5.7 4.6 3.6 5.1 3.2 1.4 1 0 0 1 1 1 0 Ycf1 Exo_endo_phos PF03372.18 EWM24315.1 - 1.8e-17 64.1 0.1 2.4e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EWM24315.1 - 2.7e-07 30.2 0.0 6.9e-07 28.8 0.0 1.7 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Fer2 PF00111.22 EWM24316.1 - 5.5e-08 32.4 2.4 1.1e-07 31.4 1.6 1.5 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain UAA PF08449.6 EWM24317.1 - 2.1e-60 204.1 12.6 2.7e-60 203.8 8.8 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EWM24317.1 - 1.1e-10 41.3 9.5 1.1e-10 41.3 6.6 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EWM24317.1 - 5.4e-06 26.4 6.0 5.4e-06 26.4 4.1 3.3 2 1 1 3 3 3 1 EamA-like transporter family Nuc_sug_transp PF04142.10 EWM24317.1 - 0.0017 17.5 0.5 0.0034 16.5 0.1 1.6 1 1 1 2 2 2 1 Nucleotide-sugar transporter UPF0233 PF06781.7 EWM24317.1 - 0.16 11.5 4.3 3.8 7.2 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0233) Aa_trans PF01490.13 EWM24318.1 - 2.8e-57 194.0 14.7 3.5e-57 193.7 10.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aldo_ket_red PF00248.16 EWM24319.1 - 6.9e-51 172.7 0.0 1.3e-30 106.2 0.0 2.1 2 0 0 2 2 2 2 Aldo/keto reductase family Pkinase PF00069.20 EWM24320.1 - 3.9e-40 137.6 0.0 5.6e-40 137.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM24320.1 - 3.8e-16 58.9 0.0 5.6e-16 58.3 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EWM24320.1 - 6.2e-08 32.6 2.1 1.4e-05 24.9 0.2 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EWM24320.1 - 6.6e-07 28.5 0.0 0.0029 16.6 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Pribosyltran PF00156.22 EWM24321.1 - 6.5e-16 58.1 0.0 1.6e-15 56.9 0.0 1.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain KH_3 PF13014.1 EWM24322.1 - 0.038 13.6 0.0 0.084 12.5 0.0 1.6 1 0 0 1 1 1 0 KH domain KH_1 PF00013.24 EWM24322.1 - 0.041 13.5 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 KH domain NAD_binding_10 PF13460.1 EWM24323.1 - 0.00032 20.7 0.0 0.00053 20.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF883 PF05957.8 EWM24324.1 - 0.0081 16.5 0.7 0.6 10.5 0.0 2.3 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF883) Holin_LLH PF09682.5 EWM24324.1 - 0.0093 16.0 1.0 2.2 8.4 0.0 2.1 1 1 1 2 2 2 2 Phage holin protein (Holin_LLH) YtxH PF12732.2 EWM24324.1 - 0.04 14.2 1.7 1.3 9.3 1.2 2.3 1 1 0 1 1 1 0 YtxH-like protein Apolipoprotein PF01442.13 EWM24324.1 - 0.083 12.3 0.0 2.9 7.3 0.0 1.9 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Ank_5 PF13857.1 EWM24325.1 - 0.00053 20.1 0.0 0.0016 18.5 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EWM24325.1 - 0.00074 19.8 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EWM24325.1 - 0.0059 17.0 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Rpn3_C PF08375.6 EWM24327.1 - 4e-20 71.9 0.1 8.8e-20 70.8 0.1 1.6 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 EWM24327.1 - 4.9e-20 71.8 0.0 1.2e-19 70.5 0.0 1.7 1 0 0 1 1 1 1 PCI domain Mito_fiss_reg PF05308.6 EWM24327.1 - 0.16 11.2 4.3 0.32 10.3 3.0 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator F-box-like PF12937.2 EWM24328.1 - 4.2e-07 29.5 0.5 9.9e-07 28.3 0.3 1.6 1 0 0 1 1 1 1 F-box-like zf-RanBP PF00641.13 EWM24328.1 - 0.0031 16.5 1.8 0.0031 16.5 1.3 2.9 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others F-box PF00646.28 EWM24328.1 - 0.0038 16.8 0.0 0.0086 15.7 0.0 1.6 1 0 0 1 1 1 1 F-box domain DZR PF12773.2 EWM24328.1 - 2.4 8.0 10.4 1.9 8.4 2.5 2.6 2 0 0 2 2 2 0 Double zinc ribbon Cytochrom_B561 PF03188.11 EWM24329.1 - 2.6e-13 50.0 10.1 3.6e-13 49.5 7.0 1.2 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4079 PF13301.1 EWM24329.1 - 0.0016 18.5 7.7 0.0016 18.4 3.5 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF4079) DUF420 PF04238.7 EWM24329.1 - 0.012 15.5 7.5 0.027 14.3 5.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF420) MIG-14_Wnt-bd PF06664.7 EWM24329.1 - 0.018 13.8 1.7 0.018 13.8 1.1 1.2 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion CTP_transf_1 PF01148.15 EWM24329.1 - 0.021 14.4 5.0 0.027 14.1 3.5 1.2 1 0 0 1 1 1 0 Cytidylyltransferase family WIF PF02019.13 EWM24329.1 - 0.073 12.5 0.1 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 WIF domain DUF2306 PF10067.4 EWM24329.1 - 0.088 12.9 13.1 0.33 11.0 0.1 3.2 1 1 2 3 3 3 0 Predicted membrane protein (DUF2306) Peptidase_C98 PF15499.1 EWM24329.1 - 0.089 12.0 0.1 0.12 11.6 0.1 1.1 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF2663 PF10864.3 EWM24329.1 - 0.12 12.6 1.9 0.18 11.9 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) DUF2607 PF10795.4 EWM24329.1 - 0.31 10.8 5.1 0.76 9.6 3.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2607) PRA1 PF03208.14 EWM24329.1 - 3.1 7.1 8.2 0.64 9.3 2.8 1.9 2 1 0 2 2 2 0 PRA1 family protein SAC3_GANP PF03399.11 EWM24330.1 - 1.6e-21 76.7 0.0 2.3e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EWM24330.1 - 1e-06 28.5 0.0 1.7e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 NUDIX PF00293.23 EWM24331.1 - 1.5e-15 57.0 0.0 6.3e-15 55.0 0.0 1.9 2 0 0 2 2 2 1 NUDIX domain ABC_tran PF00005.22 EWM24332.1 - 1.4e-28 99.8 0.0 2.7e-15 56.8 0.0 3.2 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EWM24332.1 - 2.1e-08 34.5 0.2 0.099 12.5 0.1 3.7 4 0 0 4 4 4 2 AAA domain SMC_N PF02463.14 EWM24332.1 - 7.5e-07 28.6 0.0 0.035 13.3 0.0 2.9 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EWM24332.1 - 2.1e-05 23.9 0.1 0.073 12.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EWM24332.1 - 4.7e-05 23.4 3.1 0.19 11.6 0.3 4.0 3 1 0 3 3 3 1 AAA ATPase domain SbcCD_C PF13558.1 EWM24332.1 - 0.00011 22.0 0.0 0.85 9.5 0.0 3.2 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 EWM24332.1 - 0.00025 21.8 0.0 0.64 10.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EWM24332.1 - 0.00031 20.9 0.5 2 8.5 0.0 3.6 4 0 0 4 4 4 1 AAA domain UPF0079 PF02367.12 EWM24332.1 - 0.00099 18.7 0.1 0.56 9.8 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 EWM24332.1 - 0.0015 18.1 2.7 3.5 7.2 0.0 3.9 4 1 0 4 4 4 1 NACHT domain DUF258 PF03193.11 EWM24332.1 - 0.0038 16.4 0.1 0.21 10.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 EWM24332.1 - 0.0039 17.0 0.2 0.76 9.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EWM24332.1 - 0.0086 16.3 0.3 6.2 7.1 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EWM24332.1 - 0.0087 16.4 0.4 0.94 9.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EWM24332.1 - 0.011 15.1 0.1 1 8.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EWM24332.1 - 0.011 15.8 0.0 5.2 7.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.12 EWM24332.1 - 0.042 13.2 0.8 6.4 6.1 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_10 PF12846.2 EWM24332.1 - 0.063 12.7 0.0 13 5.1 0.0 2.5 3 0 0 3 3 3 0 AAA-like domain Thymidylate_kin PF02223.12 EWM24332.1 - 0.071 12.4 0.4 0.53 9.6 0.1 2.3 2 0 0 2 2 2 0 Thymidylate kinase AAA_13 PF13166.1 EWM24332.1 - 0.099 11.0 0.0 1.4 7.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EWM24332.1 - 0.11 12.3 0.0 18 5.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 EWM24332.1 - 0.13 12.2 0.0 21 5.1 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EWM24332.1 - 0.23 10.9 0.0 3.2 7.2 0.1 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Trigger_N PF05697.8 EWM24333.1 - 6.1e-24 84.4 0.1 6.1e-24 84.4 0.1 2.5 2 1 0 2 2 2 1 Bacterial trigger factor protein (TF) Trigger_C PF05698.9 EWM24333.1 - 2.9e-09 36.9 11.4 2.9e-09 36.9 7.9 2.0 2 0 0 2 2 2 1 Bacterial trigger factor protein (TF) C-terminus FKBP_C PF00254.23 EWM24333.1 - 0.078 13.0 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase TIG PF01833.19 EWM24334.1 - 0.026 14.4 0.0 0.074 13.0 0.0 1.8 1 0 0 1 1 1 0 IPT/TIG domain TBCA PF02970.11 EWM24337.1 - 1.3e-27 95.7 6.2 1.6e-27 95.4 4.3 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A Synaphin PF05835.7 EWM24337.1 - 0.011 15.8 3.5 0.015 15.4 2.4 1.3 1 1 0 1 1 1 0 Synaphin protein Telomere_reg-2 PF10193.4 EWM24337.1 - 0.26 11.5 2.1 6.1 7.1 0.0 2.1 1 1 1 2 2 2 0 Telomere length regulation protein APG6 PF04111.7 EWM24337.1 - 0.47 9.4 4.3 0.56 9.2 3.0 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 CobN-Mg_chel PF02514.11 EWM24338.1 - 2.9e-259 862.7 0.0 6.6e-226 752.3 0.0 2.7 2 1 0 2 2 2 2 CobN/Magnesium Chelatase DUF3479 PF11965.3 EWM24338.1 - 3.8e-34 117.8 0.0 9e-34 116.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3479) RRP14 PF15459.1 EWM24339.1 - 7.9e-16 57.8 4.1 7.9e-16 57.8 2.8 3.2 3 0 0 3 3 3 1 60S ribosome biogenesis protein Rrp14 Nop14 PF04147.7 EWM24339.1 - 0.00022 19.3 30.3 0.00031 18.8 21.0 1.2 1 0 0 1 1 1 1 Nop14-like family TFIIA PF03153.8 EWM24339.1 - 0.18 11.6 16.4 0.21 11.4 11.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CobT PF06213.7 EWM24339.1 - 0.98 8.4 23.2 1.4 7.9 16.1 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Daxx PF03344.10 EWM24339.1 - 1.5 7.1 35.1 2.8 6.3 24.3 1.4 1 1 0 1 1 1 0 Daxx Family CDC45 PF02724.9 EWM24339.1 - 1.6 6.7 17.5 1.9 6.4 12.1 1.3 1 0 0 1 1 1 0 CDC45-like protein GMC_oxred_N PF00732.14 EWM24341.1 - 6.4e-51 173.2 0.0 9e-51 172.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EWM24341.1 - 7.7e-27 94.3 0.1 1.2e-26 93.6 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EWM24341.1 - 0.0016 18.3 0.0 0.0042 17.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EWM24341.1 - 0.0024 16.8 0.5 0.0037 16.2 0.3 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EWM24341.1 - 0.0059 15.5 1.9 0.054 12.3 0.2 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EWM24341.1 - 0.0093 15.8 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EWM24341.1 - 0.085 11.3 0.2 0.19 10.1 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein GMC_oxred_N PF00732.14 EWM24342.1 - 1e-38 133.2 0.0 1.5e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EWM24342.1 - 5.1e-27 94.9 0.1 8e-27 94.2 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase adh_short PF00106.20 EWM24343.1 - 3.2e-24 85.7 1.0 5.5e-24 84.9 0.7 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EWM24343.1 - 1.9e-13 50.7 0.3 2.7e-13 50.2 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EWM24343.1 - 2.7e-08 33.6 1.1 4.2e-08 33.0 0.8 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EWM24343.1 - 8.6e-06 25.0 0.0 7.4e-05 22.0 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) SPC22 PF04573.7 EWM24344.1 - 7.1e-40 136.0 0.3 1.1e-39 135.4 0.2 1.3 1 0 0 1 1 1 1 Signal peptidase subunit GRP PF07172.6 EWM24345.1 - 0.0033 17.8 1.0 0.0047 17.3 0.7 1.3 1 0 0 1 1 1 1 Glycine rich protein family DUF788 PF05620.6 EWM24345.1 - 0.022 14.6 0.1 0.022 14.6 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF788) DUF2201_N PF13203.1 EWM24345.1 - 0.067 12.3 1.8 0.078 12.1 1.2 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain CP12 PF02672.10 EWM24345.1 - 0.077 13.4 2.3 0.14 12.6 1.6 1.4 1 0 0 1 1 1 0 CP12 domain Ank_4 PF13637.1 EWM24346.1 - 3.6e-24 84.6 2.1 2.6e-07 30.9 0.1 3.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 EWM24346.1 - 2.5e-18 66.1 0.0 7.7e-09 35.7 0.0 2.5 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EWM24346.1 - 4e-17 61.0 1.7 8.7e-09 34.7 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EWM24346.1 - 2.1e-16 59.5 1.7 1.2e-09 38.0 0.0 4.3 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM24346.1 - 3.8e-13 48.2 0.5 0.00014 21.7 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat DUF1843 PF08898.5 EWM24346.1 - 0.017 15.1 0.0 1.5 8.9 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) SAM_2 PF07647.12 EWM24346.1 - 0.17 11.7 0.1 8.9 6.2 0.0 2.5 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) PhyH PF05721.8 EWM24347.1 - 6.4e-15 55.7 0.1 6.6e-14 52.4 0.0 2.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Ctr PF04145.10 EWM24349.1 - 5e-22 78.4 0.8 6.7e-22 78.1 0.6 1.2 1 0 0 1 1 1 1 Ctr copper transporter family RseC_MucC PF04246.7 EWM24349.1 - 0.15 11.5 1.2 6.5 6.3 0.0 2.2 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Myb_DNA-binding PF00249.26 EWM24350.1 - 0.00015 21.7 0.0 0.00025 21.0 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EWM24350.1 - 0.038 14.0 0.0 0.058 13.4 0.0 1.2 1 0 0 1 1 1 0 Myb-like DNA-binding domain Zn_clus PF00172.13 EWM24351.1 - 0.00017 21.3 7.1 0.00031 20.5 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med15 PF09606.5 EWM24351.1 - 0.00087 17.6 44.9 0.0019 16.4 31.2 1.6 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 EWM24351.1 - 0.0059 14.9 36.4 0.0079 14.5 25.2 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Response_reg PF00072.19 EWM24351.1 - 0.014 15.4 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Response regulator receiver domain Suf PF05843.9 EWM24351.1 - 0.06 13.0 11.6 0.092 12.4 8.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Tim54 PF11711.3 EWM24351.1 - 0.93 8.0 8.4 1.6 7.2 5.9 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CPSF100_C PF13299.1 EWM24351.1 - 4.4 7.4 9.8 8.1 6.6 6.8 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Ctr PF04145.10 EWM24351.1 - 7.4 6.6 5.3 20 5.2 3.7 1.7 1 0 0 1 1 1 0 Ctr copper transporter family BRF1 PF07741.8 EWM24351.1 - 7.8 6.7 11.3 1 9.6 4.7 1.9 2 0 0 2 2 2 0 Brf1-like TBP-binding domain NARP1 PF12569.3 EWM24351.1 - 9.9 4.7 13.4 14 4.2 9.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Fe_hyd_lg_C PF02906.9 EWM24352.1 - 3.9e-100 334.7 0.0 4.6e-100 334.5 0.0 1.0 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.12 EWM24352.1 - 2e-22 78.9 0.8 3.2e-22 78.2 0.6 1.3 1 0 0 1 1 1 1 Iron hydrogenase small subunit DUF21 PF01595.15 EWM24354.1 - 4.9e-38 130.2 3.1 1e-37 129.1 2.2 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EWM24354.1 - 2.9e-19 68.5 0.4 9.9e-11 41.2 0.0 3.3 3 0 0 3 3 3 2 CBS domain CorC_HlyC PF03471.12 EWM24354.1 - 7.3e-17 60.9 0.7 1.7e-16 59.7 0.2 1.8 2 0 0 2 2 2 1 Transporter associated domain WD40 PF00400.27 EWM24356.1 - 1.4e-09 37.4 0.2 0.046 13.6 0.0 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat Radical_SAM PF04055.16 EWM24357.1 - 5.8e-13 49.3 0.0 1e-12 48.5 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Radical_SAM PF04055.16 EWM24358.1 - 3.2e-13 50.1 0.0 5.7e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily BATS PF06968.8 EWM24359.1 - 3.9e-18 65.0 0.0 1e-17 63.7 0.0 1.8 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 EWM24359.1 - 1.7e-06 28.3 0.0 4.9e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Radical SAM superfamily XdhC_C PF13478.1 EWM24359.1 - 0.062 13.6 0.0 0.53 10.5 0.0 2.3 2 0 0 2 2 2 0 XdhC Rossmann domain Pam16 PF03656.8 EWM24359.1 - 0.092 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Pam16 PQQ_2 PF13360.1 EWM24360.1 - 0.023 14.1 0.4 1 8.7 0.2 2.7 2 1 0 2 2 2 0 PQQ-like domain PQQ_3 PF13570.1 EWM24360.1 - 0.65 10.3 5.2 3.6 8.0 0.1 4.1 5 0 0 5 5 5 0 PQQ-like domain PQQ_2 PF13360.1 EWM24361.1 - 0.019 14.4 0.4 0.97 8.8 0.1 2.7 2 1 0 2 2 2 0 PQQ-like domain PQQ_3 PF13570.1 EWM24361.1 - 0.56 10.5 5.3 3.4 8.0 0.1 4.2 5 0 0 5 5 5 0 PQQ-like domain CheB_methylest PF01339.12 EWM24362.1 - 0.0077 15.6 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 CheB methylesterase XH PF03469.9 EWM24364.1 - 3.3e-07 30.0 0.0 6.4e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 XH domain FA_FANCE PF11510.3 EWM24365.1 - 3.5e-06 26.3 0.5 0.0013 17.9 0.3 2.2 2 0 0 2 2 2 2 Fanconi Anaemia group E protein FANCE L27_2 PF09045.5 EWM24365.1 - 0.0037 16.7 0.0 0.009 15.5 0.0 1.6 1 0 0 1 1 1 1 L27_2 FA_FANCE PF11510.3 EWM24366.1 - 9.8e-05 21.6 1.5 0.0011 18.1 0.3 2.1 2 0 0 2 2 2 2 Fanconi Anaemia group E protein FANCE MutS_I PF01624.15 EWM24367.1 - 4.5e-13 49.2 0.0 7.8e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 MutS domain I DNA_pol3_tau_4 PF12168.3 EWM24367.1 - 0.14 12.6 3.5 0.32 11.4 1.9 2.0 1 1 0 1 1 1 0 DNA polymerase III subunits tau domain IV DnaB-binding SIS PF01380.17 EWM24368.1 - 1.7e-32 111.8 0.2 6.4e-16 58.1 0.0 2.9 3 0 0 3 3 3 2 SIS domain GATase_6 PF13522.1 EWM24368.1 - 1.1e-24 86.9 0.2 3.5e-24 85.2 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EWM24368.1 - 7.4e-17 61.2 0.0 1.9e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EWM24368.1 - 4.8e-16 58.4 2.4 3.8e-11 42.3 0.7 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_4 PF13230.1 EWM24368.1 - 4.4e-05 22.2 0.4 7.4e-05 21.5 0.2 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Epimerase PF01370.16 EWM24370.1 - 7.6e-22 77.8 0.0 8.8e-20 71.1 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EWM24370.1 - 1.6e-15 57.5 0.0 2.9e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EWM24370.1 - 2.7e-07 30.1 0.0 3.9e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 EWM24370.1 - 5.9e-06 25.3 0.0 0.00014 20.9 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EWM24370.1 - 0.00087 19.2 0.0 0.0028 17.5 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase DUF2686 PF10887.3 EWM24370.1 - 0.018 13.7 0.0 0.028 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2686) KR PF08659.5 EWM24370.1 - 0.065 12.8 0.0 0.54 9.9 0.0 2.0 2 0 0 2 2 2 0 KR domain Glyco_transf_4 PF13439.1 EWM24370.1 - 0.086 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 NAD_binding_8 PF13450.1 EWM24370.1 - 0.12 12.4 0.0 0.41 10.6 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DDE_Tnp_4 PF13359.1 EWM24373.1 - 0.0018 17.8 0.0 0.52 9.9 0.0 2.1 2 0 0 2 2 2 2 DDE superfamily endonuclease Glutaredoxin PF00462.19 EWM24375.1 - 1.4e-16 60.2 0.0 1.9e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 EWM24375.1 - 0.00031 20.8 0.0 0.00045 20.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EWM24375.1 - 0.025 14.5 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DSBA PF01323.15 EWM24375.1 - 0.077 12.5 0.1 4 6.9 0.0 2.1 2 0 0 2 2 2 0 DSBA-like thioredoxin domain DUF295 PF03478.13 EWM24375.1 - 0.15 11.4 0.3 0.36 10.2 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF295) Tyr-DNA_phospho PF06087.7 EWM24376.1 - 8.5e-29 100.4 0.0 1.2e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase MutS_V PF00488.16 EWM24377.1 - 6e-37 127.2 0.0 2.1e-25 89.5 0.0 2.2 2 0 0 2 2 2 2 MutS domain V GIY-YIG PF01541.19 EWM24377.1 - 0.0022 18.3 0.0 0.0036 17.6 0.0 1.3 1 0 0 1 1 1 1 GIY-YIG catalytic domain AAA_23 PF13476.1 EWM24377.1 - 0.0031 17.8 0.1 0.005 17.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EWM24377.1 - 0.065 12.6 0.0 0.21 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EWM24377.1 - 0.097 12.2 0.3 0.25 10.8 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ank_4 PF13637.1 EWM24378.1 - 3.1e-18 65.7 2.4 7.8e-06 26.2 0.1 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 EWM24378.1 - 1.9e-17 63.3 0.9 3.9e-11 43.1 1.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EWM24378.1 - 2e-12 46.9 0.4 2.9e-06 27.3 0.0 3.4 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM24378.1 - 1.4e-11 43.4 1.8 0.044 14.0 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.25 EWM24378.1 - 3.9e-11 42.1 4.9 0.037 13.8 0.0 4.8 4 1 0 4 4 4 4 Ankyrin repeat MSP PF01716.13 EWM24379.1 - 2.5e-93 311.6 0.4 3.1e-93 311.3 0.3 1.1 1 0 0 1 1 1 1 Manganese-stabilising protein / photosystem II polypeptide MSP PF01716.13 EWM24380.1 - 3.6e-52 176.8 0.1 4.5e-52 176.5 0.0 1.1 1 0 0 1 1 1 1 Manganese-stabilising protein / photosystem II polypeptide Amidohydro_1 PF01979.15 EWM24381.1 - 2e-34 119.7 0.0 3.2e-34 119.0 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EWM24381.1 - 1.1e-06 28.1 0.3 0.00023 20.5 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EWM24381.1 - 1.5e-05 25.2 11.1 0.00021 21.3 7.7 2.6 1 1 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 EWM24381.1 - 2.5e-05 23.3 0.1 4.1e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_5 PF13594.1 EWM24381.1 - 0.0016 18.2 0.0 0.0046 16.7 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase QRPTase_C PF01729.14 EWM24382.1 - 9.7e-57 191.1 0.0 1.4e-56 190.6 0.0 1.3 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 EWM24382.1 - 1.8e-17 62.9 0.0 7.5e-17 60.9 0.0 2.0 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Pkinase PF00069.20 EWM24383.1 - 7.9e-68 228.4 0.0 1.1e-67 227.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM24383.1 - 5.1e-33 114.2 0.0 8.2e-33 113.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EWM24383.1 - 0.0018 17.3 0.0 0.0031 16.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EWM24383.1 - 0.01 15.6 0.1 0.026 14.2 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Mito_fiss_reg PF05308.6 EWM24383.1 - 0.19 11.0 1.5 0.42 9.9 1.0 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator PBP1_TM PF14812.1 EWM24384.1 - 0.37 11.1 8.9 0.47 10.7 6.1 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CD99L2 PF12301.3 EWM24384.1 - 2.5 7.7 9.3 3.3 7.3 6.4 1.1 1 0 0 1 1 1 0 CD99 antigen like protein 2 BTV_NS2 PF04514.7 EWM24384.1 - 5.3 5.8 5.7 5.9 5.6 3.9 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Pro_isomerase PF00160.16 EWM24385.1 - 4.7e-29 101.6 0.0 7.6e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SR-25 PF10500.4 EWM24385.1 - 0.13 11.7 16.8 0.22 10.9 11.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BAF1_ABF1 PF04684.8 EWM24385.1 - 0.68 8.7 3.3 0.96 8.2 2.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Period_C PF12114.3 EWM24385.1 - 2.5 7.6 13.1 3.7 7.0 9.1 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Macoilin PF09726.4 EWM24385.1 - 2.7 6.1 9.3 18 3.4 7.2 1.6 2 0 0 2 2 2 0 Transmembrane protein Apt1 PF10351.4 EWM24385.1 - 4 6.1 6.6 5.2 5.8 4.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pro_isomerase PF00160.16 EWM24386.1 - 2e-29 102.8 0.0 2.5e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ras PF00071.17 EWM24387.1 - 5.1e-27 94.2 0.0 3.2e-26 91.6 0.0 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EWM24387.1 - 3.1e-09 37.3 0.0 7.3e-09 36.1 0.0 1.6 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EWM24387.1 - 1.7e-06 27.6 0.0 4.9e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EWM24387.1 - 3.3e-05 23.8 0.0 5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EWM24387.1 - 0.0042 16.2 0.0 0.0074 15.4 0.0 1.4 1 1 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 EWM24387.1 - 0.0042 16.9 0.0 0.17 11.6 0.0 2.2 2 0 0 2 2 2 1 Dynamin family AAA_16 PF13191.1 EWM24387.1 - 0.019 14.9 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 EWM24387.1 - 0.028 15.2 0.1 0.46 11.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.7 EWM24387.1 - 0.04 13.0 0.0 0.084 11.9 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF258 PF03193.11 EWM24387.1 - 0.044 12.9 0.0 0.1 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 EWM24387.1 - 0.049 13.9 0.0 0.068 13.4 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Semialdhyde_dh PF01118.19 EWM24388.1 - 1.2e-06 28.7 0.0 1.9e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EWM24388.1 - 2e-06 27.9 0.1 2.5e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EWM24388.1 - 0.023 13.6 0.0 1.4 7.8 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein DUF21 PF01595.15 EWM24392.1 - 0.18 11.0 0.4 0.43 9.8 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function DUF21 DUF2576 PF10845.3 EWM24394.1 - 0.092 11.9 2.4 0.25 10.5 1.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) Lectin_N PF03954.9 EWM24394.1 - 0.21 10.9 5.6 0.18 11.2 1.3 2.8 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain DUF1664 PF07889.7 EWM24394.1 - 0.87 9.3 15.5 1.2 8.9 2.4 4.2 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.5 EWM24394.1 - 0.96 9.5 16.1 5 7.2 2.6 4.5 4 1 1 5 5 5 0 Fibrinogen alpha/beta chain family DUF948 PF06103.6 EWM24394.1 - 2.2 8.1 8.3 12 5.8 0.2 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.7 EWM24394.1 - 8.3 6.7 10.6 7 6.9 0.2 3.7 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein BSD PF03909.12 EWM24396.1 - 2.3e-07 30.4 0.0 5.9e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 BSD domain FTA4 PF13093.1 EWM24396.1 - 0.029 13.7 0.1 0.042 13.2 0.1 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 CDC45 PF02724.9 EWM24396.1 - 0.056 11.4 1.0 0.074 11.0 0.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Whirly PF08536.6 EWM24398.1 - 1.7e-05 24.3 0.0 2.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Whirly transcription factor ADK PF00406.17 EWM24402.1 - 1.4e-10 41.2 0.0 1.6e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EWM24402.1 - 0.022 15.0 0.0 0.039 14.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain End_N_terminal PF12218.3 EWM24402.1 - 0.023 14.1 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase AAA_33 PF13671.1 EWM24402.1 - 0.036 13.9 0.0 0.048 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 EWM24402.1 - 0.11 11.9 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Thymidylate kinase ELMO_CED12 PF04727.8 EWM24403.1 - 3e-27 95.2 0.0 3.8e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 ELMO/CED-12 family Ion_trans PF00520.26 EWM24405.1 - 3.1e-12 46.1 2.4 3.1e-12 46.1 1.7 1.6 2 0 0 2 2 2 1 Ion transport protein Cytochrom_B_N PF00033.14 EWM24405.1 - 0.01 15.2 2.0 0.13 11.6 0.6 2.2 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Ion_trans_2 PF07885.11 EWM24407.1 - 1.5e-06 27.7 5.2 2.2e-06 27.2 3.6 1.3 1 0 0 1 1 1 1 Ion channel DUF16 PF01519.11 EWM24407.1 - 0.28 11.4 5.2 2.1 8.5 3.6 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF16 YebO PF13974.1 EWM24407.1 - 1.4 8.7 4.4 9 6.1 0.1 2.8 3 0 0 3 3 3 0 YebO-like protein DUF16 PF01519.11 EWM24408.1 - 0.15 12.3 5.3 1.1 9.5 3.7 2.0 1 1 0 1 1 1 0 Protein of unknown function DUF16 YebO PF13974.1 EWM24408.1 - 0.75 9.6 3.1 5.3 6.8 0.1 2.1 2 0 0 2 2 2 0 YebO-like protein DUF2201_N PF13203.1 EWM24410.1 - 0.34 10.0 6.8 0.56 9.3 4.7 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain NARP1 PF12569.3 EWM24410.1 - 0.87 8.2 4.5 1.1 7.9 3.1 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Nucleoplasmin PF03066.10 EWM24413.1 - 0.0024 17.4 6.4 0.003 17.0 4.4 1.2 1 0 0 1 1 1 1 Nucleoplasmin HSP70 PF00012.15 EWM24413.1 - 0.033 12.1 8.9 0.42 8.4 6.2 1.9 1 1 0 1 1 1 0 Hsp70 protein Pilt PF15453.1 EWM24413.1 - 0.28 10.8 3.7 0.34 10.5 2.5 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Daxx PF03344.10 EWM24413.1 - 0.36 9.2 8.6 0.37 9.2 5.9 1.1 1 0 0 1 1 1 0 Daxx Family BSP_II PF05432.6 EWM24413.1 - 0.42 9.8 13.5 0.52 9.5 9.4 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) YqfQ PF14181.1 EWM24413.1 - 0.86 9.6 4.2 1.8 8.5 2.9 1.5 1 0 0 1 1 1 0 YqfQ-like protein Myc_N PF01056.13 EWM24413.1 - 1.1 8.3 7.0 1.4 7.9 4.8 1.2 1 0 0 1 1 1 0 Myc amino-terminal region TEX19 PF15553.1 EWM24413.1 - 1.4 8.7 7.7 2.3 8.0 5.3 1.3 1 0 0 1 1 1 0 Testis-expressed protein 19 VID27 PF08553.5 EWM24413.1 - 1.6 6.8 8.2 2 6.5 5.7 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein DNA_pol_phi PF04931.8 EWM24413.1 - 1.8 6.2 15.1 2.1 6.0 10.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi DinB_2 PF12867.2 EWM24415.1 - 0.077 13.3 0.0 0.091 13.0 0.0 1.3 1 0 0 1 1 1 0 DinB superfamily IMS_C PF11799.3 EWM24416.1 - 0.069 13.0 2.1 3.9 7.4 0.1 2.3 2 0 0 2 2 2 0 impB/mucB/samB family C-terminal domain Methyltransf_23 PF13489.1 EWM24417.1 - 4.9e-05 23.0 0.0 8.1e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_S8 PF00082.17 EWM24418.1 - 1.3e-13 50.8 0.1 1.4e-13 50.6 0.1 1.0 1 0 0 1 1 1 1 Subtilase family Peptidase_S8 PF00082.17 EWM24419.1 - 4.4e-08 32.6 0.4 4.4e-08 32.6 0.3 1.0 1 0 0 1 1 1 1 Subtilase family DUF2007 PF09413.5 EWM24419.1 - 0.077 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2007) DUF2020 PF09449.5 EWM24419.1 - 0.16 11.6 3.3 0.19 11.3 1.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF2020) ALMT PF11744.3 EWM24419.1 - 0.16 10.5 0.2 0.19 10.3 0.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF863 PF05904.6 EWM24420.1 - 1.7 6.8 6.1 2.4 6.3 4.2 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF863) Totivirus_coat PF05518.6 EWM24420.1 - 3 5.5 14.7 4.7 4.9 10.2 1.2 1 0 0 1 1 1 0 Totivirus coat protein Metallophos PF00149.23 EWM24421.1 - 6.3e-25 87.7 0.0 1.1e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 EWM24421.1 - 5.1e-13 48.8 0.2 3.1e-12 46.3 0.1 2.3 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 EWM24421.1 - 2.8e-07 29.4 0.9 3.7e-06 25.7 0.1 2.2 2 0 0 2 2 2 1 PhoD-like phosphatase Metallophos_2 PF12850.2 EWM24421.1 - 1e-05 25.4 0.0 1.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EWM24423.1 - 2.6e-26 92.2 0.1 1.3e-25 90.0 0.0 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 EWM24423.1 - 2e-13 50.1 0.1 5.9e-13 48.6 0.1 1.9 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 EWM24423.1 - 1.2e-07 30.6 0.9 3.4e-06 25.8 0.1 2.2 2 0 0 2 2 2 2 PhoD-like phosphatase Metallophos_2 PF12850.2 EWM24423.1 - 1.8e-05 24.6 0.0 3.4e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain zf-CCCH PF00642.19 EWM24424.1 - 0.0034 17.0 3.8 0.0058 16.2 2.6 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PA28_alpha PF02251.13 EWM24425.1 - 0.00077 19.5 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 Proteasome activator pa28 alpha subunit GARS_C PF02843.11 EWM24425.1 - 0.1 12.8 0.2 0.14 12.3 0.2 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, C domain RRM_1 PF00076.17 EWM24426.1 - 1.3e-17 63.1 0.0 1.3e-16 59.9 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM24426.1 - 2.5e-13 49.8 0.0 1e-12 47.8 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM24426.1 - 1.6e-09 37.4 0.0 2.4e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVWC PF15430.1 EWM24427.1 - 0.2 12.1 1.9 3.3 8.2 0.1 2.2 1 1 1 2 2 2 0 Single domain von Willebrand factor type C zf-CCCH_2 PF14608.1 EWM24427.1 - 0.34 10.9 2.6 0.7 9.9 0.4 2.2 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type zf-CCCH PF00642.19 EWM24427.1 - 0.64 9.7 5.6 0.41 10.3 0.9 2.3 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Mito_fiss_reg PF05308.6 EWM24431.1 - 0.42 9.9 3.3 0.73 9.1 2.3 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Tyrosinase PF00264.15 EWM24434.1 - 1.3e-05 25.4 3.7 0.008 16.3 0.3 2.7 2 0 0 2 2 2 2 Common central domain of tyrosinase DUF3451 PF11933.3 EWM24438.1 - 0.021 14.6 0.1 0.021 14.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3451) MoaC PF01967.16 EWM24442.1 - 1.4e-44 151.1 0.0 1.9e-44 150.5 0.0 1.2 1 0 0 1 1 1 1 MoaC family F-box-like PF12937.2 EWM24444.1 - 9.5e-08 31.6 2.2 2.3e-06 27.2 0.2 2.4 2 0 0 2 2 2 2 F-box-like F-box PF00646.28 EWM24444.1 - 0.027 14.1 0.5 0.051 13.2 0.0 1.8 2 0 0 2 2 2 0 F-box domain Spore_coat_CotO PF14153.1 EWM24445.1 - 0.11 11.8 17.2 0.57 9.5 11.6 2.0 2 0 0 2 2 2 0 Spore coat protein CotO Tom37_C PF11801.3 EWM24445.1 - 0.68 9.7 6.7 1.1 9.1 4.7 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain CDC27 PF09507.5 EWM24445.1 - 1.6 7.8 23.9 2.2 7.4 16.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MIP-T3 PF10243.4 EWM24445.1 - 1.6 7.0 29.8 2 6.7 20.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 TEX19 PF15553.1 EWM24445.1 - 2 8.2 12.8 0.83 9.5 6.7 1.8 1 1 1 2 2 2 0 Testis-expressed protein 19 CENP-N PF05238.8 EWM24445.1 - 2.2 7.2 7.9 2.3 7.1 5.5 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like DUF2413 PF10310.4 EWM24445.1 - 2.8 6.6 15.5 3.6 6.3 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Hid1 PF12722.2 EWM24445.1 - 3.8 5.0 5.6 4.5 4.8 3.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.9 EWM24445.1 - 6.2 4.7 24.1 8.6 4.2 16.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.7 EWM24445.1 - 7.3 4.1 16.5 9.1 3.8 11.5 1.0 1 0 0 1 1 1 0 Ycf1 DnaJ PF00226.26 EWM24446.1 - 2e-08 33.8 0.0 4e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain DUF737 PF05300.6 EWM24446.1 - 2.4 8.0 11.3 0.87 9.5 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF737) Dynamin_N PF00350.18 EWM24449.1 - 1.6e-10 41.0 0.0 2.3e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 EWM24449.1 - 3.9e-05 24.1 0.0 5.6e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EWM24449.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase UPF0079 PF02367.12 EWM24449.1 - 0.055 13.0 0.0 0.084 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 EWM24449.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EWM24450.1 - 7.7e-24 84.4 0.9 1.2e-23 83.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EWM24450.1 - 1e-12 48.9 2.7 1.1e-11 45.6 1.9 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EWM24450.1 - 4.2e-05 23.2 0.3 8e-05 22.3 0.2 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 EWM24450.1 - 4.3e-05 23.7 0.1 0.00016 21.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EWM24450.1 - 5.3e-05 23.1 0.4 0.0029 17.4 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.1 EWM24450.1 - 0.00011 22.1 1.1 0.00032 20.7 0.0 2.1 2 1 0 2 2 2 1 AAA domain ADK PF00406.17 EWM24450.1 - 0.00012 21.9 0.2 0.00083 19.2 0.0 2.1 2 1 0 2 2 2 1 Adenylate kinase AAA_11 PF13086.1 EWM24450.1 - 0.0016 18.0 1.0 0.0046 16.5 0.7 1.8 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EWM24450.1 - 0.0019 17.6 0.0 0.0035 16.8 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family T2SE PF00437.15 EWM24450.1 - 0.0023 16.8 0.1 0.004 16.0 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 EWM24450.1 - 0.0039 17.2 0.2 0.0094 15.9 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.10 EWM24450.1 - 0.0044 16.7 0.7 0.016 14.8 0.0 1.9 2 0 0 2 2 2 1 NTPase AAA_5 PF07728.9 EWM24450.1 - 0.0045 16.7 0.1 0.018 14.7 0.1 1.9 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 EWM24450.1 - 0.0074 16.6 0.3 0.014 15.7 0.2 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EWM24450.1 - 0.0074 16.4 0.4 0.0074 16.4 0.3 1.9 2 2 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EWM24450.1 - 0.011 15.2 0.2 0.036 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain Zeta_toxin PF06414.7 EWM24450.1 - 0.019 14.0 1.2 0.063 12.3 0.1 2.2 2 1 1 3 3 3 0 Zeta toxin SKI PF01202.17 EWM24450.1 - 0.03 14.2 2.0 0.27 11.1 1.4 2.0 1 1 0 1 1 1 0 Shikimate kinase Sigma54_activ_2 PF14532.1 EWM24450.1 - 0.033 14.2 0.0 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain KTI12 PF08433.5 EWM24450.1 - 0.038 13.2 0.1 0.12 11.5 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 KaiC PF06745.8 EWM24450.1 - 0.038 13.0 1.0 0.059 12.4 0.1 1.6 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.1 EWM24450.1 - 0.039 13.5 0.6 0.08 12.5 0.4 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EWM24450.1 - 0.051 12.9 0.1 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EWM24450.1 - 0.054 12.4 0.3 0.089 11.7 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TrwB_AAD_bind PF10412.4 EWM24450.1 - 0.061 11.9 0.1 0.11 11.1 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Sigma54_activat PF00158.21 EWM24450.1 - 0.065 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.1 EWM24450.1 - 0.089 12.3 0.1 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EWM24450.1 - 0.09 11.8 0.0 0.17 10.8 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EWM24450.1 - 0.092 12.1 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 EWM24450.1 - 0.1 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 EWM24450.1 - 0.15 12.3 0.4 0.25 11.6 0.3 1.7 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 EWM24450.1 - 0.16 11.5 0.1 0.33 10.5 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ThiF PF00899.16 EWM24451.1 - 1.2e-10 41.2 0.1 1.9e-10 40.7 0.1 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EWM24451.1 - 0.003 17.6 0.0 0.0049 16.9 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EWM24451.1 - 0.0049 16.8 0.1 0.0085 16.0 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 EWM24451.1 - 0.013 14.5 0.6 0.016 14.2 0.4 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF1275 PF06912.6 EWM24451.1 - 0.025 13.7 0.1 0.043 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) FAD_binding_3 PF01494.14 EWM24451.1 - 0.039 13.0 0.3 0.052 12.6 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.16 EWM24451.1 - 0.043 13.3 0.1 0.06 12.9 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.11 EWM24451.1 - 0.053 12.9 0.1 0.094 12.1 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Ldh_1_N PF00056.18 EWM24451.1 - 0.073 12.8 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DAO PF01266.19 EWM24451.1 - 0.088 11.6 0.2 0.14 11.0 0.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase KR PF08659.5 EWM24451.1 - 0.16 11.6 0.6 0.61 9.7 0.0 1.9 2 0 0 2 2 2 0 KR domain 3HCDH_N PF02737.13 EWM24451.1 - 0.17 11.5 0.4 0.25 11.0 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-C3HC4_4 PF15227.1 EWM24452.1 - 0.00013 21.7 2.8 0.00013 21.7 1.9 2.1 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EWM24452.1 - 0.0027 17.7 6.0 0.0027 17.7 4.2 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EWM24452.1 - 0.0043 16.8 8.7 0.0043 16.8 6.0 2.8 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.1 EWM24452.1 - 0.0069 16.0 0.8 0.0069 16.0 0.6 1.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EWM24452.1 - 0.01 15.4 5.1 0.01 15.4 3.6 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Dynamin_N PF00350.18 EWM24454.1 - 1.4e-09 37.9 0.0 1.9e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EWM24454.1 - 9.6e-06 25.5 0.0 1.3e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EWM24454.1 - 0.003 17.0 0.1 0.0083 15.5 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain His_Phos_1 PF00300.17 EWM24455.1 - 0.0028 17.7 0.0 0.0038 17.3 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ndc1_Nup PF09531.5 EWM24456.1 - 0.055 11.9 4.8 0.049 12.0 3.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pex14_N PF04695.8 EWM24456.1 - 0.11 12.5 6.4 0.11 12.5 4.5 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF566 PF04484.7 EWM24456.1 - 3.9 6.8 20.1 4.3 6.7 13.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Tir_receptor_N PF07490.6 EWM24456.1 - 5 6.6 9.3 7.8 6.0 6.4 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus Apt1 PF10351.4 EWM24456.1 - 9.6 4.9 15.7 12 4.6 10.9 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Mito_fiss_reg PF05308.6 EWM24458.1 - 4.1 6.6 8.6 6.9 5.9 5.9 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator TauE PF01925.14 EWM24459.1 - 4.1e-05 23.1 0.5 8.1e-05 22.1 0.0 1.7 2 0 0 2 2 2 1 Sulfite exporter TauE/SafE DLH PF01738.13 EWM24460.1 - 8.7e-10 38.2 0.0 1.1e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.2 EWM24460.1 - 0.001 19.0 0.2 0.0015 18.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family VWA_2 PF13519.1 EWM24460.1 - 0.0037 17.3 0.1 0.0075 16.3 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain IFT57 PF10498.4 EWM24460.1 - 0.25 10.0 5.1 0.33 9.6 3.5 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Myc_N PF01056.13 EWM24460.1 - 0.8 8.8 4.0 1.1 8.3 2.8 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Daxx PF03344.10 EWM24460.1 - 3.1 6.1 10.8 3.9 5.8 7.5 1.1 1 0 0 1 1 1 0 Daxx Family SAP PF02037.22 EWM24461.1 - 7.4e-11 41.2 0.7 7.4e-11 41.2 0.5 1.7 2 0 0 2 2 2 1 SAP domain Hydrolase_3 PF08282.7 EWM24462.1 - 1e-06 28.5 0.0 0.0033 17.0 0.0 3.0 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EWM24462.1 - 0.00086 18.6 0.0 0.0033 16.7 0.0 1.9 2 1 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase Sulfate_transp PF00916.15 EWM24463.1 - 7e-54 182.7 6.9 1.2e-53 181.9 4.8 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EWM24463.1 - 7.8e-25 86.3 2.1 7.8e-25 86.3 1.4 3.2 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EWM24463.1 - 1.1e-19 70.0 1.2 1.4e-19 69.6 0.1 1.7 2 0 0 2 2 2 1 STAS domain STAS_2 PF13466.1 EWM24463.1 - 0.0009 19.2 0.1 0.0021 18.0 0.1 1.7 1 0 0 1 1 1 1 STAS domain PRMT5 PF05185.11 EWM24463.1 - 0.0046 15.9 0.1 0.007 15.3 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Sulfate_transp PF00916.15 EWM24464.1 - 5.5e-54 183.0 6.9 8.6e-54 182.4 4.8 1.3 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EWM24464.1 - 6.2e-25 86.6 2.1 6.2e-25 86.6 1.4 3.4 5 0 0 5 5 5 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EWM24464.1 - 0.00019 20.8 0.1 0.00055 19.3 0.0 1.8 2 0 0 2 2 2 1 STAS domain PRMT5 PF05185.11 EWM24464.1 - 0.0038 16.2 0.1 0.0056 15.6 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Urm1 PF09138.6 EWM24466.1 - 0.026 14.6 0.1 7.6 6.7 0.0 2.9 1 1 2 3 3 3 0 Urm1 (Ubiquitin related modifier) PT PF04886.7 EWM24468.1 - 4.5e-21 73.8 179.6 0.091 12.0 12.2 10.4 1 1 5 6 6 6 3 PT repeat DUF543 PF04418.7 EWM24469.1 - 3.9e-07 29.9 0.0 5.7e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Peptidase_M41 PF01434.13 EWM24473.1 - 7.5e-70 234.7 0.6 1.1e-69 234.1 0.4 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EWM24473.1 - 7e-42 142.7 0.0 1.3e-41 141.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EWM24473.1 - 0.0003 20.9 0.0 0.035 14.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EWM24473.1 - 0.00096 19.9 0.0 0.0036 18.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EWM24473.1 - 0.0016 18.1 0.2 0.027 14.1 0.1 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EWM24473.1 - 0.0025 16.5 0.1 0.005 15.6 0.1 1.4 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 EWM24473.1 - 0.003 17.0 0.0 0.0077 15.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 EWM24473.1 - 0.0039 16.6 0.6 0.03 13.7 0.2 2.2 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EWM24473.1 - 0.0041 16.2 0.1 0.015 14.4 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_2 PF07724.9 EWM24473.1 - 0.0057 16.5 0.1 0.026 14.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 EWM24473.1 - 0.012 14.7 0.1 0.064 12.4 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 EWM24473.1 - 0.014 14.5 0.0 0.028 13.4 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EWM24473.1 - 0.017 14.9 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EWM24473.1 - 0.02 14.8 0.0 0.046 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EWM24473.1 - 0.023 14.4 1.4 0.08 12.6 0.7 2.2 2 0 0 2 2 1 0 Part of AAA domain AAA_18 PF13238.1 EWM24473.1 - 0.028 14.7 0.0 0.36 11.1 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 EWM24473.1 - 0.03 14.2 0.5 0.32 10.9 0.1 2.6 2 1 1 3 3 3 0 AAA ATPase domain Ribosomal_L16 PF00252.13 EWM24475.1 - 1.3e-30 105.8 1.1 1.6e-30 105.6 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Mito_carr PF00153.22 EWM24477.1 - 5.7e-21 74.0 5.2 5.6e-16 58.0 0.1 4.0 3 1 1 4 4 4 4 Mitochondrial carrier protein Romo1 PF10247.4 EWM24477.1 - 0.25 11.5 4.0 2.8 8.2 0.7 2.5 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Proteasome PF00227.21 EWM24478.1 - 8.9e-11 41.4 0.0 1.1e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF1997 PF09366.5 EWM24481.1 - 6e-11 42.3 0.1 1.6e-10 40.9 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1997) DUF4185 PF13810.1 EWM24481.1 - 0.085 11.7 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4185) Calpain_inhib PF00748.14 EWM24483.1 - 0.0056 17.0 0.5 0.0056 17.0 0.4 2.0 2 0 0 2 2 2 1 Calpain inhibitor DUF2910 PF11139.3 EWM24484.1 - 0.00075 18.6 0.0 0.0047 16.0 0.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF2910) HupE_UreJ_2 PF13795.1 EWM24484.1 - 0.012 15.0 0.7 0.012 15.0 0.5 3.4 2 1 2 4 4 4 0 HupE / UreJ protein TctB PF07331.6 EWM24484.1 - 0.014 15.0 0.2 0.014 15.0 0.2 3.2 2 2 1 3 3 3 0 Tripartite tricarboxylate transporter TctB family DUF308 PF03729.8 EWM24484.1 - 0.035 14.1 15.0 0.072 13.0 1.0 4.4 3 2 1 4 4 4 0 Short repeat of unknown function (DUF308) DUF4064 PF13273.1 EWM24484.1 - 0.64 10.1 5.5 1.8 8.6 0.2 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) Mog1 PF04603.7 EWM24485.1 - 1e-30 106.5 0.1 1.4e-30 106.0 0.1 1.2 1 0 0 1 1 1 1 Ran-interacting Mog1 protein ABC1 PF03109.11 EWM24486.1 - 0.079 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Spc97_Spc98 PF04130.8 EWM24487.1 - 1.4e-10 40.1 0.0 1.5e-10 40.0 0.0 1.0 1 0 0 1 1 1 1 Spc97 / Spc98 family Thioesterase PF00975.15 EWM24488.1 - 8.4e-14 52.3 0.0 3.8e-13 50.2 0.0 1.8 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.2 EWM24488.1 - 1.4e-07 31.6 2.1 1.8e-07 31.3 1.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM24488.1 - 0.0017 18.1 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family adh_short PF00106.20 EWM24489.1 - 2.2e-21 76.5 0.0 3.1e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EWM24489.1 - 1.9e-09 37.6 0.0 3.2e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EWM24489.1 - 2e-08 34.1 0.1 6.3e-08 32.4 0.0 1.7 1 1 0 1 1 1 1 KR domain UPF0128 PF03673.8 EWM24489.1 - 0.0013 18.0 0.0 0.011 15.0 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0128) DUF1776 PF08643.5 EWM24489.1 - 0.0063 15.6 0.0 0.0094 15.1 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.10 EWM24489.1 - 0.008 15.1 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EWM24489.1 - 0.015 15.3 0.0 0.068 13.1 0.0 1.9 2 0 0 2 2 2 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EWM24489.1 - 0.023 14.4 0.0 0.063 13.0 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EWM24489.1 - 0.03 13.7 0.1 0.11 11.8 0.1 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EWM24490.1 - 2.9e-21 76.1 0.0 3.9e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EWM24490.1 - 2.5e-09 37.2 0.0 4.2e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EWM24490.1 - 2.7e-08 33.7 0.1 8.1e-08 32.1 0.0 1.7 1 1 0 1 1 1 1 KR domain UPF0128 PF03673.8 EWM24490.1 - 0.0018 17.6 0.0 0.013 14.8 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0128) DUF1776 PF08643.5 EWM24490.1 - 0.0076 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.10 EWM24490.1 - 0.01 14.7 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EWM24490.1 - 0.019 14.9 0.0 0.086 12.8 0.0 1.8 2 0 0 2 2 2 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EWM24490.1 - 0.029 14.1 0.0 0.072 12.8 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EWM24490.1 - 0.038 13.4 0.1 0.14 11.5 0.1 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF728 PF05304.7 EWM24494.1 - 0.12 12.5 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF728) Aldedh PF00171.17 EWM24499.1 - 7.4e-34 116.8 0.1 7.9e-34 116.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Lzipper-MIP1 PF14389.1 EWM24499.1 - 0.027 14.5 0.4 0.067 13.3 0.3 1.6 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DUF885 PF05960.6 EWM24499.1 - 0.03 13.5 0.2 0.038 13.1 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) LuxC PF05893.9 EWM24499.1 - 0.047 12.4 0.1 0.24 10.0 0.0 2.0 1 1 1 2 2 2 0 Acyl-CoA reductase (LuxC) NTP_transf_2 PF01909.18 EWM24501.1 - 0.006 16.8 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 EWM24503.1 - 8.4e-11 41.6 0.0 2.7e-10 40.0 0.0 1.9 1 0 0 1 1 1 1 Cid1 family poly A polymerase OAS1_C PF10421.4 EWM24503.1 - 0.0033 16.9 0.0 0.0058 16.1 0.0 1.3 1 0 0 1 1 1 1 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus AAA_27 PF13514.1 EWM24503.1 - 0.24 9.0 5.6 0.32 8.6 3.9 1.0 1 0 0 1 1 1 0 AAA domain LRR_4 PF12799.2 EWM24504.1 - 5.6e-10 38.6 7.8 7.4e-05 22.2 0.1 3.4 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EWM24504.1 - 0.00031 20.4 14.5 0.002 17.8 2.7 3.3 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 EWM24504.1 - 0.0011 18.7 12.1 2.7 8.3 0.0 4.9 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_9 PF14580.1 EWM24504.1 - 0.2 11.2 4.4 0.23 11.0 0.2 3.1 2 1 1 3 3 3 0 Leucine-rich repeat MerE PF05052.7 EWM24507.1 - 1.4 8.9 6.2 2.8 7.9 3.6 1.9 1 1 1 2 2 2 0 MerE protein HEAT PF02985.17 EWM24510.1 - 0.0027 17.6 0.2 1.5 9.1 0.0 3.2 3 0 0 3 3 3 2 HEAT repeat Proteasom_PSMB PF10508.4 EWM24510.1 - 0.15 10.3 0.0 8.9 4.4 0.0 2.1 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit CactinC_cactus PF09732.4 EWM24511.1 - 5.7e-56 187.4 7.1 6.9e-56 187.2 4.9 1.1 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Sulfotransfer_1 PF00685.22 EWM24512.1 - 0.015 14.6 0.0 0.074 12.2 0.0 1.9 2 0 0 2 2 2 0 Sulfotransferase domain Peptidase_M48 PF01435.13 EWM24513.1 - 1.5e-28 99.9 0.1 2.3e-28 99.3 0.1 1.3 1 1 0 1 1 1 1 Peptidase family M48 DUF2201_N PF13203.1 EWM24513.1 - 0.014 14.6 0.0 0.11 11.7 0.1 2.0 2 0 0 2 2 2 0 Putative metallopeptidase domain DUF955 PF06114.8 EWM24513.1 - 0.022 14.4 0.2 0.05 13.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF955) DUF2268 PF10026.4 EWM24513.1 - 0.11 11.8 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) Proteasom_PSMB PF10508.4 EWM24514.1 - 1.2e-11 43.5 0.0 5.1e-11 41.5 0.0 1.7 1 1 0 1 1 1 1 Proteasome non-ATPase 26S subunit CBM49 PF09478.5 EWM24515.1 - 0.0066 16.5 0.1 0.019 15.0 0.0 1.7 1 1 0 1 1 1 1 Carbohydrate binding domain CBM49 fn1 PF00039.13 EWM24515.1 - 0.043 13.6 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 Fibronectin type I domain Exo_endo_phos PF03372.18 EWM24516.1 - 1.2e-12 48.3 0.0 1.7e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UBA PF00627.26 EWM24517.1 - 7.3e-12 44.7 0.2 1.1e-11 44.1 0.1 1.4 1 0 0 1 1 1 1 UBA/TS-N domain CUE PF02845.11 EWM24517.1 - 0.00043 19.7 0.5 0.0054 16.1 0.1 2.4 2 0 0 2 2 2 1 CUE domain UBA_4 PF14555.1 EWM24517.1 - 0.028 13.9 0.1 0.048 13.1 0.1 1.4 1 0 0 1 1 1 0 UBA-like domain ubiquitin PF00240.18 EWM24518.1 - 1.9e-16 59.1 0.0 2.9e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EWM24518.1 - 2e-10 40.1 0.1 3.1e-10 39.5 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EWM24518.1 - 0.037 14.2 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain BBP1_N PF15271.1 EWM24518.1 - 0.34 11.2 0.0 0.34 11.2 0.0 1.7 2 0 0 2 2 2 0 Spindle pole body component BBP1, Mps2-binding protein DUF605 PF04652.11 EWM24518.1 - 0.48 9.7 5.9 0.54 9.6 4.1 1.1 1 0 0 1 1 1 0 Vta1 like DUF3460 PF11943.3 EWM24518.1 - 0.85 9.7 4.4 0.53 10.4 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3460) DUF3901 PF13040.1 EWM24518.1 - 4.6 6.5 7.4 3.1 7.1 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3901) GRIP PF01465.15 EWM24519.1 - 1.1e-09 37.6 0.0 2.1e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 GRIP domain TMCO5 PF14992.1 EWM24519.1 - 1.5 7.8 14.8 3.3 6.7 0.2 2.3 2 0 0 2 2 2 0 TMCO5 family IncA PF04156.9 EWM24519.1 - 2.2 7.8 18.8 6 6.4 0.7 2.4 2 0 0 2 2 2 0 IncA protein PUB PF09409.5 EWM24520.1 - 9.1e-14 50.9 0.0 2.1e-13 49.8 0.0 1.6 2 0 0 2 2 2 1 PUB domain ubiquitin PF00240.18 EWM24520.1 - 1.9e-09 36.7 0.0 2.8e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EWM24520.1 - 0.0033 17.0 0.0 0.0065 16.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF937 PF06078.6 EWM24520.1 - 0.66 10.1 11.1 2.1 8.5 7.7 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF937) DUF914 PF06027.7 EWM24522.1 - 5.2e-78 262.2 0.2 5.4e-43 147.1 0.2 2.1 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EWM24522.1 - 2.6e-06 27.4 15.6 0.0034 17.4 5.3 3.0 2 1 1 3 3 3 2 EamA-like transporter family UAA PF08449.6 EWM24522.1 - 2.8e-05 23.2 1.2 5.6e-05 22.2 0.0 2.0 2 1 0 2 2 2 1 UAA transporter family TPT PF03151.11 EWM24522.1 - 2 8.0 7.1 3.8 7.1 0.2 3.0 2 1 0 2 2 2 0 Triose-phosphate Transporter family TctB PF07331.6 EWM24522.1 - 4.3 6.9 10.8 0.076 12.6 0.4 2.6 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family HMG_box PF00505.14 EWM24523.1 - 1.7e-16 60.1 1.1 3e-16 59.4 0.8 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EWM24523.1 - 2.2e-13 50.3 0.9 4.2e-13 49.4 0.6 1.5 1 0 0 1 1 1 1 HMG-box domain FA_desaturase PF00487.19 EWM24524.1 - 1.7e-12 47.3 14.7 1.7e-12 47.3 10.2 1.6 1 1 1 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.3 EWM24524.1 - 0.00034 20.6 0.0 0.00056 19.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) FA_desaturase PF00487.19 EWM24525.1 - 0.073 12.5 0.1 0.075 12.4 0.0 1.1 1 0 0 1 1 1 0 Fatty acid desaturase FA_desaturase PF00487.19 EWM24526.1 - 0.0035 16.8 0.7 0.0046 16.4 0.5 1.1 1 0 0 1 1 1 1 Fatty acid desaturase MCM_N PF14551.1 EWM24527.1 - 1e-17 64.7 0.0 1.7e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 MCM N-terminal domain MCM PF00493.18 EWM24527.1 - 4.4e-08 32.3 0.0 6.4e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family DAO PF01266.19 EWM24528.1 - 9.1e-11 41.2 0.3 4.9e-10 38.8 0.2 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EWM24528.1 - 3.7e-09 36.4 0.2 9.2e-09 35.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain PRMT5 PF05185.11 EWM24528.1 - 0.0011 17.9 0.0 0.0016 17.4 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase NAD_binding_9 PF13454.1 EWM24528.1 - 0.0014 18.4 0.1 0.003 17.3 0.1 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Amino_oxidase PF01593.19 EWM24528.1 - 0.0037 16.4 0.1 0.061 12.3 0.1 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 EWM24528.1 - 0.0044 16.9 0.2 0.0073 16.2 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EWM24528.1 - 0.0079 14.8 0.5 0.012 14.2 0.3 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox PF00070.22 EWM24528.1 - 0.059 13.7 0.4 0.87 10.0 0.6 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EWM24528.1 - 0.13 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 EWM24528.1 - 0.18 10.6 1.8 0.33 9.7 1.2 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.14 EWM24528.1 - 0.23 10.4 0.8 0.77 8.7 0.5 1.7 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.19 EWM24529.1 - 9.1e-11 41.2 0.3 4.9e-10 38.8 0.2 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EWM24529.1 - 3.7e-09 36.4 0.2 9.2e-09 35.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain PRMT5 PF05185.11 EWM24529.1 - 0.0011 17.9 0.0 0.0016 17.4 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase NAD_binding_9 PF13454.1 EWM24529.1 - 0.0014 18.4 0.1 0.003 17.3 0.1 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Amino_oxidase PF01593.19 EWM24529.1 - 0.0037 16.4 0.1 0.061 12.3 0.1 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 EWM24529.1 - 0.0044 16.9 0.2 0.0073 16.2 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EWM24529.1 - 0.0079 14.8 0.5 0.012 14.2 0.3 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox PF00070.22 EWM24529.1 - 0.059 13.7 0.4 0.87 10.0 0.6 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EWM24529.1 - 0.13 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 EWM24529.1 - 0.18 10.6 1.8 0.33 9.7 1.2 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.14 EWM24529.1 - 0.23 10.4 0.8 0.77 8.7 0.5 1.7 2 0 0 2 2 2 0 FAD binding domain SOUL PF04832.7 EWM24530.1 - 1e-39 135.9 0.0 1.2e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 SOUL heme-binding protein Kelch_3 PF13415.1 EWM24531.1 - 4.8e-12 45.6 18.1 2.6e-07 30.6 0.0 7.1 8 1 0 8 8 8 3 Galactose oxidase, central domain Kelch_4 PF13418.1 EWM24531.1 - 5.5e-12 45.2 17.9 1.2e-07 31.4 0.0 5.9 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EWM24531.1 - 9.9e-12 44.5 5.4 0.00042 20.1 0.0 5.7 6 1 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 EWM24531.1 - 1.1e-08 34.4 0.0 4.6e-05 22.8 0.0 4.6 4 0 0 4 4 4 1 Kelch motif Kelch_6 PF13964.1 EWM24531.1 - 6.1e-06 26.1 0.1 0.0085 16.2 0.0 4.3 4 0 0 4 4 4 1 Kelch motif RRM_6 PF14259.1 EWM24532.1 - 2.7e-37 126.5 0.0 3.9e-12 45.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EWM24532.1 - 7.8e-25 86.3 0.0 5.1e-08 32.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM24532.1 - 1.8e-11 43.7 0.0 0.00023 20.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EWM24532.1 - 0.034 13.9 0.0 19 5.1 0.0 2.9 3 0 0 3 3 3 0 RNA binding motif MCM PF00493.18 EWM24533.1 - 1.1e-64 218.3 0.1 1.3e-64 218.0 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase_2 PF13335.1 EWM24533.1 - 0.0091 16.3 1.0 0.028 14.8 0.1 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Claudin_2 PF13903.1 EWM24534.1 - 5.5 6.6 9.9 29 4.3 6.7 2.1 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Yip1 PF04893.12 EWM24535.1 - 1.6e-05 24.5 0.1 2.1e-05 24.1 0.1 1.1 1 0 0 1 1 1 1 Yip1 domain Lipase_GDSL_2 PF13472.1 EWM24536.1 - 3.1e-10 40.4 0.2 1.6e-09 38.1 0.1 2.5 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EWM24536.1 - 8.4e-06 25.7 0.0 7.2e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase Dynein_heavy PF03028.10 EWM24537.1 - 4e-118 395.4 0.0 1.2e-117 393.8 0.0 1.7 1 1 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor MT PF12777.2 EWM24537.1 - 1.1e-45 155.9 6.3 1.7e-45 155.2 4.4 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 EWM24537.1 - 3.9e-40 137.1 0.0 8.7e-40 135.9 0.0 1.6 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 CENP-F_leu_zip PF10473.4 EWM24537.1 - 0.00092 19.0 1.5 0.00092 19.0 1.1 3.6 4 0 0 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.4 EWM24537.1 - 6.1 5.6 14.3 4.7 6.0 0.4 2.6 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Asp_protease_2 PF13650.1 EWM24538.1 - 2.9e-13 50.1 0.5 2.4e-06 27.9 0.1 2.6 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.1 EWM24538.1 - 3.5e-08 33.1 0.0 0.00013 21.6 0.0 2.4 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease RVP PF00077.15 EWM24538.1 - 0.00057 19.7 0.0 0.0041 17.0 0.0 2.1 2 0 0 2 2 2 1 Retroviral aspartyl protease SAP PF02037.22 EWM24538.1 - 0.00063 19.1 0.1 0.001 18.5 0.1 1.3 1 0 0 1 1 1 1 SAP domain Asp_protease PF09668.5 EWM24538.1 - 0.0022 17.5 0.0 1 8.9 0.0 2.2 2 0 0 2 2 2 2 Aspartyl protease AAA_6 PF12774.2 EWM24539.1 - 1.6e-79 266.7 0.0 2.1e-79 266.3 0.0 1.1 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_5 PF07728.9 EWM24539.1 - 6.9e-05 22.5 0.0 0.013 15.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EWM24539.1 - 0.025 14.5 0.1 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 EWM24539.1 - 0.042 14.0 0.0 0.091 12.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.20 EWM24540.1 - 2.1e-51 174.5 0.0 7.1e-47 159.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EWM24540.1 - 9.7e-31 106.7 0.0 3.7e-29 101.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EWM24540.1 - 4.2e-05 22.6 0.0 7.6e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like CLP_protease PF00574.18 EWM24541.1 - 1.3e-48 165.0 0.0 2.1e-48 164.3 0.0 1.3 1 1 0 1 1 1 1 Clp protease Pkinase PF00069.20 EWM24542.1 - 8.4e-57 192.2 0.0 9.8e-57 192.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM24542.1 - 1.5e-36 125.7 0.0 2.1e-36 125.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EWM24542.1 - 7.5e-05 21.8 0.0 9.1e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Docking PF08990.6 EWM24543.1 - 0.049 12.8 1.0 0.13 11.4 0.7 1.6 1 0 0 1 1 1 0 Erythronolide synthase docking Snf7 PF03357.16 EWM24544.1 - 1.3e-40 138.5 6.0 1.3e-40 138.5 4.1 1.6 2 0 0 2 2 2 1 Snf7 TBPIP PF07106.8 EWM24545.1 - 3.2e-28 98.3 0.0 3.2e-28 98.3 0.0 1.6 2 0 0 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Penicillinase_R PF03965.11 EWM24545.1 - 0.00019 21.5 0.0 0.00095 19.2 0.0 2.1 2 0 0 2 2 2 1 Penicillinase repressor IncA PF04156.9 EWM24545.1 - 0.023 14.2 0.5 0.023 14.2 0.3 2.2 2 0 0 2 2 2 0 IncA protein FUR PF01475.14 EWM24545.1 - 0.034 14.0 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 Ferric uptake regulator family TrmB PF01978.14 EWM24545.1 - 0.036 13.7 0.0 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB CDC45 PF02724.9 EWM24545.1 - 0.1 10.5 13.6 1.3 6.9 10.0 2.2 2 0 0 2 2 2 0 CDC45-like protein DUF1978 PF09321.5 EWM24546.1 - 0.043 13.2 1.7 0.058 12.8 1.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1978) U79_P34 PF03064.11 EWM24546.1 - 0.074 12.5 7.7 0.1 12.1 5.3 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Adeno_VII PF03228.9 EWM24546.1 - 0.19 12.3 2.3 0.32 11.6 1.6 1.3 1 0 0 1 1 1 0 Adenoviral core protein VII PX PF00787.19 EWM24547.1 - 2.4e-15 56.3 0.0 4.2e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 PX domain DUF1823 PF08853.6 EWM24548.1 - 2.1e-26 91.9 0.5 1.3e-25 89.3 0.3 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1823) His_Phos_2 PF00328.17 EWM24549.1 - 1.9e-15 57.0 0.0 6.6e-15 55.2 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PBP1_TM PF14812.1 EWM24550.1 - 0.56 10.5 32.9 0.22 11.8 12.3 2.3 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal P12 PF12669.2 EWM24550.1 - 0.71 10.1 2.4 19 5.5 0.1 2.7 2 0 0 2 2 2 0 Virus attachment protein p12 family PRP21_like_P PF12230.3 EWM24550.1 - 1.7 8.0 12.6 3.8 6.9 0.1 2.1 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein BUD22 PF09073.5 EWM24550.1 - 1.8 7.5 20.9 2.5 7.0 14.5 1.2 1 0 0 1 1 1 0 BUD22 SpoIIIAH PF12685.2 EWM24550.1 - 1.9 7.9 7.7 2.4 7.5 5.3 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein TFIIA PF03153.8 EWM24550.1 - 2.2 8.0 9.4 3.2 7.5 6.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Polyoma_coat2 PF00761.15 EWM24550.1 - 2.8 7.3 4.5 3.6 6.9 3.1 1.1 1 0 0 1 1 1 0 Polyomavirus coat protein Zip PF02535.17 EWM24550.1 - 5.1 6.0 6.2 9.5 5.1 4.3 1.5 1 1 0 1 1 1 0 ZIP Zinc transporter SAPS PF04499.10 EWM24550.1 - 8.9 4.8 9.8 11 4.5 6.8 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2763 PF10961.3 EWM24551.1 - 0.02 15.2 0.6 0.029 14.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) Protoglobin PF11563.3 EWM24551.1 - 0.045 13.4 0.1 0.066 12.8 0.0 1.4 1 1 0 1 1 1 0 Protoglobin NmrA PF05368.8 EWM24553.1 - 7.9e-24 84.2 0.0 1e-23 83.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EWM24553.1 - 8.4e-24 84.5 0.0 1.1e-23 84.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EWM24553.1 - 1.5e-10 40.9 0.0 2.2e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EWM24553.1 - 4.9e-05 22.4 0.1 6.3e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 EWM24553.1 - 0.0004 19.1 0.0 0.0006 18.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EWM24553.1 - 0.011 15.6 0.6 0.021 14.7 0.3 1.7 2 1 0 2 2 2 0 short chain dehydrogenase NAD_binding_4 PF07993.7 EWM24553.1 - 0.026 13.4 0.0 0.12 11.3 0.0 1.9 2 0 0 2 2 2 0 Male sterility protein Semialdhyde_dh PF01118.19 EWM24553.1 - 0.12 12.6 0.1 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain WD40 PF00400.27 EWM24554.1 - 5.5e-20 70.4 12.9 3.8e-08 32.9 0.1 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat Abhydrolase_6 PF12697.2 EWM24555.1 - 1.5e-14 54.4 1.4 2.2e-14 53.8 1.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM24555.1 - 9.1e-09 35.2 0.3 1.8e-08 34.2 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EWM24555.1 - 0.0092 15.5 0.1 0.022 14.3 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) HCV_NS4b PF01001.14 EWM24555.1 - 0.014 14.7 0.6 0.028 13.8 0.4 1.5 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4b DDOST_48kD PF03345.9 EWM24556.1 - 4.8e-111 371.2 0.0 6e-111 370.9 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF4350 PF14258.1 EWM24556.1 - 0.041 14.0 0.0 0.097 12.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) Cyto_heme_lyase PF01265.12 EWM24557.1 - 2.8 7.4 14.9 5.6 6.4 10.3 1.5 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase Hydrolase PF00702.21 EWM24559.1 - 2.9e-23 83.3 0.0 7.6e-21 75.5 0.0 3.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EWM24559.1 - 7.7e-20 71.8 0.0 2.4e-19 70.2 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EWM24559.1 - 9.4e-15 54.2 3.2 1.3e-14 53.8 0.2 2.6 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.7 EWM24559.1 - 0.0018 17.9 0.3 0.035 13.6 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EWM24559.1 - 0.0029 17.5 0.0 0.015 15.2 0.0 2.2 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Barttin PF15462.1 EWM24559.1 - 7.5 6.1 6.7 23 4.5 0.5 2.4 2 0 0 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) SNF2_N PF00176.18 EWM24560.1 - 2.9e-62 210.1 1.1 4.4e-62 209.5 0.8 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain PHD PF00628.24 EWM24560.1 - 7.5e-34 115.2 86.4 4.9e-09 35.7 4.2 7.6 8 0 0 8 8 8 6 PHD-finger Helicase_C PF00271.26 EWM24560.1 - 2.1e-17 62.7 0.0 4.1e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Bromodomain PF00439.20 EWM24560.1 - 6.6e-15 54.8 0.0 3.1e-14 52.6 0.0 2.2 2 0 0 2 2 2 1 Bromodomain Chromo PF00385.19 EWM24560.1 - 4.3e-12 45.5 3.1 2e-08 33.7 0.2 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain PHD_2 PF13831.1 EWM24560.1 - 7.6e-08 31.5 40.8 9.7e-05 21.6 1.3 5.6 6 0 0 6 6 6 4 PHD-finger ResIII PF04851.10 EWM24560.1 - 1.4e-06 28.2 0.0 4.4e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EWM24560.1 - 3.8e-05 23.2 0.0 0.00011 21.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-C2H2_jaz PF12171.3 EWM24560.1 - 0.009 16.1 2.9 4.8 7.4 0.2 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding S10_plectin PF03501.10 EWM24561.1 - 4.1e-35 119.5 0.3 6e-35 118.9 0.2 1.2 1 0 0 1 1 1 1 Plectin/S10 domain Sterol_MT_C PF08498.5 EWM24562.1 - 1.1e-23 82.9 0.1 2e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EWM24562.1 - 4.7e-18 65.4 0.0 1.1e-17 64.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EWM24562.1 - 6.4e-17 61.5 0.0 1.1e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 EWM24562.1 - 1.1e-16 60.7 0.0 2e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM24562.1 - 4.5e-15 55.7 0.0 7.9e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM24562.1 - 1.2e-10 41.9 0.0 7.3e-10 39.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM24562.1 - 8.6e-10 38.8 0.0 1.8e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EWM24562.1 - 3.3e-08 32.9 0.0 5.8e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EWM24562.1 - 9.3e-08 32.4 0.0 1.8e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM24562.1 - 4.1e-07 30.0 0.1 1.4e-06 28.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 EWM24562.1 - 0.049 13.1 0.0 0.086 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 EWM24562.1 - 0.052 12.9 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_15 PF09445.5 EWM24562.1 - 0.062 12.8 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase MTS PF05175.9 EWM24562.1 - 0.14 11.5 0.0 0.29 10.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain GTP_EFTU PF00009.22 EWM24563.1 - 3.3e-47 160.3 0.0 5.8e-47 159.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EWM24563.1 - 1.4e-18 66.8 0.1 5.9e-18 64.8 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EWM24563.1 - 2.1e-12 46.9 1.5 4.8e-12 45.8 1.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EWM24563.1 - 0.00011 22.1 0.0 0.00031 20.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase PAM2 PF07145.10 EWM24563.1 - 0.0026 17.1 3.1 0.012 15.0 0.9 2.4 1 1 1 2 2 2 2 Ataxin-2 C-terminal region MgtE PF01769.11 EWM24565.1 - 0.39 10.9 2.3 0.41 10.9 0.5 1.7 2 0 0 2 2 2 0 Divalent cation transporter DUF605 PF04652.11 EWM24565.1 - 0.39 10.0 4.3 0.5 9.7 3.0 1.1 1 0 0 1 1 1 0 Vta1 like Nop PF01798.13 EWM24566.1 - 9.3e-59 197.0 0.4 9.3e-59 197.0 0.3 1.6 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 EWM24566.1 - 7.5e-24 83.2 0.1 1.4e-23 82.4 0.1 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain DDHD PF02862.12 EWM24566.1 - 0.4 10.4 5.2 0.54 10.0 3.6 1.4 1 0 0 1 1 1 0 DDHD domain RNA_polI_A34 PF08208.6 EWM24566.1 - 0.58 9.8 28.4 0.82 9.3 19.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF3408 PF11888.3 EWM24566.1 - 2.6 7.9 13.9 35 4.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) CDC45 PF02724.9 EWM24566.1 - 8.5 4.2 13.1 11 3.9 9.1 1.1 1 0 0 1 1 1 0 CDC45-like protein HGTP_anticodon PF03129.15 EWM24567.1 - 3.6e-19 68.4 0.0 6.3e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain DUF1820 PF08850.6 EWM24567.1 - 0.027 14.5 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1820) NOP5NT PF08156.8 EWM24568.1 - 1.6e-23 82.6 0.1 2.2e-23 82.1 0.1 1.2 1 0 0 1 1 1 1 NOP5NT (NUC127) domain DUF690 PF05108.8 EWM24568.1 - 0.12 10.6 0.0 0.15 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF690) LysM PF01476.15 EWM24569.1 - 0.0012 18.6 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 LysM domain PDZ_2 PF13180.1 EWM24569.1 - 0.014 15.2 1.4 0.053 13.4 0.1 2.5 2 1 0 2 2 2 0 PDZ domain zf-RING_2 PF13639.1 EWM24570.1 - 2.1e-15 56.2 5.1 2.1e-15 56.2 3.5 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EWM24570.1 - 1.7e-09 37.6 1.2 3.2e-09 36.7 0.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EWM24570.1 - 3.2e-09 36.3 2.5 3.2e-09 36.3 1.8 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EWM24570.1 - 4.6e-09 35.8 2.4 4.6e-09 35.8 1.7 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EWM24570.1 - 4.9e-07 29.3 3.6 4.9e-07 29.3 2.5 2.9 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EWM24570.1 - 6.2e-07 29.3 4.3 6.2e-07 29.3 3.0 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EWM24570.1 - 0.0003 20.5 0.5 0.00065 19.4 0.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 EWM24570.1 - 0.065 13.1 4.5 0.21 11.5 3.1 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 EWM24570.1 - 0.17 11.9 4.6 0.56 10.2 3.1 1.9 1 1 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.1 EWM24570.1 - 3.5 7.2 10.3 0.16 11.5 2.6 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Shisa PF13908.1 EWM24570.1 - 7 6.7 10.2 0.065 13.4 0.8 2.2 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator zf-RING_2 PF13639.1 EWM24571.1 - 2.5e-09 36.8 13.0 3.9e-06 26.5 0.3 3.4 3 0 0 3 3 3 2 Ring finger domain zf-rbx1 PF12678.2 EWM24571.1 - 0.00056 19.9 3.3 0.1 12.6 0.5 2.4 2 0 0 2 2 2 2 RING-H2 zinc finger zf-RING_5 PF14634.1 EWM24571.1 - 0.0029 17.2 0.1 0.0029 17.2 0.1 2.7 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EWM24571.1 - 0.0044 16.6 13.8 0.13 11.9 0.2 3.5 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EWM24571.1 - 0.7 9.6 15.4 0.48 10.1 0.2 3.9 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EWM24571.1 - 7 6.7 18.4 0.84 9.7 0.4 4.0 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) ATP-sulfurylase PF01747.12 EWM24572.1 - 8.4e-64 214.8 0.0 1.2e-63 214.3 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 EWM24572.1 - 1.5e-45 154.4 0.0 2.2e-45 153.9 0.0 1.2 1 0 0 1 1 1 1 PUA-like domain Med6 PF04934.9 EWM24573.1 - 1.9e-31 108.5 0.0 2.6e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component Med6 PF04934.9 EWM24574.1 - 1.9e-31 108.4 0.0 2.6e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component dCMP_cyt_deam_1 PF00383.17 EWM24575.1 - 2.4e-16 59.2 0.2 3.5e-14 52.2 0.1 2.1 1 1 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region XOO_2897-deam PF14440.1 EWM24575.1 - 0.0056 16.3 0.0 0.0078 15.9 0.0 1.3 1 0 0 1 1 1 1 Xanthomonas XOO_2897-like deaminase OTT_1508_deam PF14441.1 EWM24575.1 - 0.023 14.5 0.1 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 OTT_1508-like deaminase Bd3614-deam PF14439.1 EWM24575.1 - 0.72 9.7 4.2 7.3 6.4 2.9 2.1 1 1 0 1 1 1 0 Bd3614-like deaminase Nucleotid_trans PF03407.11 EWM24576.1 - 2e-28 99.6 0.1 2.7e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase BCAS2 PF05700.6 EWM24577.1 - 5.8e-52 176.3 1.8 7.5e-52 175.9 1.3 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) DUF1192 PF06698.6 EWM24577.1 - 0.081 12.7 1.4 0.19 11.5 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) DUF1843 PF08898.5 EWM24577.1 - 0.22 11.5 3.7 1.1 9.3 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) DNA_topoisoIV PF00521.15 EWM24577.1 - 0.46 9.2 3.7 0.61 8.8 2.6 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A IncA PF04156.9 EWM24577.1 - 2.2 7.8 6.9 20 4.6 5.3 1.8 2 0 0 2 2 2 0 IncA protein Sybindin PF04099.7 EWM24578.1 - 2.1e-43 147.4 0.0 2.6e-43 147.1 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EWM24578.1 - 3.6e-08 33.3 0.0 4.6e-08 32.9 0.0 1.4 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region tRNA-synt_2b PF00587.20 EWM24579.1 - 5e-44 149.9 0.1 8.4e-44 149.1 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_SAD PF07973.9 EWM24579.1 - 1.7e-13 50.1 0.0 3.8e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF3936 PF13072.1 EWM24579.1 - 0.035 13.5 0.3 0.082 12.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3936) Ribosomal_S5 PF00333.15 EWM24580.1 - 4.7e-28 96.7 0.9 1.1e-27 95.5 0.6 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EWM24580.1 - 1.2e-23 82.1 0.0 2.1e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Apo-CIII PF05778.7 EWM24581.1 - 0.029 13.7 0.2 0.42 10.0 0.0 2.4 2 0 0 2 2 2 0 Apolipoprotein CIII (Apo-CIII) SNARE PF05739.14 EWM24582.1 - 4.6e-09 35.8 0.2 5.2e-09 35.6 0.1 1.0 1 0 0 1 1 1 1 SNARE domain DUF939_C PF11728.3 EWM24582.1 - 0.016 14.9 0.0 0.018 14.8 0.0 1.0 1 0 0 1 1 1 0 DUF939 C-terminal domain HTH_40 PF14493.1 EWM24582.1 - 0.025 14.7 0.1 0.028 14.6 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain RmuC PF02646.11 EWM24582.1 - 0.079 11.7 0.1 0.081 11.7 0.1 1.0 1 0 0 1 1 1 0 RmuC family Phage_tail_X PF05489.7 EWM24582.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Phage Tail Protein X PspA_IM30 PF04012.7 EWM24582.1 - 0.24 10.7 1.4 0.25 10.6 1.0 1.1 1 0 0 1 1 1 0 PspA/IM30 family Methyltransf_31 PF13847.1 EWM24583.1 - 6.4e-15 55.0 0.0 2.3e-14 53.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM24583.1 - 2.2e-11 44.0 0.0 3.9e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM24583.1 - 6.2e-11 42.6 0.0 1.3e-10 41.5 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM24583.1 - 2.1e-10 41.1 0.0 3.2e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM24583.1 - 2.3e-09 37.1 0.0 3.4e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EWM24583.1 - 2.5e-07 30.0 0.0 4.9e-07 29.0 0.0 1.5 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EWM24583.1 - 1.5e-06 28.2 0.0 2.1e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM24583.1 - 1.5e-05 25.2 0.0 0.00034 20.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 EWM24583.1 - 0.0001 22.3 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 EWM24583.1 - 0.00012 21.5 0.0 0.00023 20.5 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain PCMT PF01135.14 EWM24583.1 - 0.00035 20.1 0.0 0.00053 19.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 EWM24583.1 - 0.0015 17.5 0.0 0.002 17.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_9 PF08003.6 EWM24583.1 - 0.0046 15.7 0.0 0.0059 15.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Fibrillarin PF01269.12 EWM24583.1 - 0.011 14.6 0.0 0.031 13.1 0.0 1.7 2 0 0 2 2 2 0 Fibrillarin Methyltransf_4 PF02390.12 EWM24583.1 - 0.012 14.6 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_16 PF10294.4 EWM24583.1 - 0.012 15.0 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase GCD14 PF08704.5 EWM24583.1 - 0.028 13.9 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_24 PF13578.1 EWM24583.1 - 0.031 15.1 0.0 0.061 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EWM24584.1 - 9.3e-15 54.5 0.0 4.7e-14 52.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM24584.1 - 1.3e-11 44.8 0.0 2.2e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM24584.1 - 3.3e-11 43.5 0.0 7.5e-11 42.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM24584.1 - 1.2e-10 41.9 0.0 1.7e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM24584.1 - 2.7e-09 36.9 0.0 3.6e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EWM24584.1 - 1.2e-07 31.1 0.0 2.8e-07 29.9 0.0 1.5 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EWM24584.1 - 1.1e-06 28.6 0.0 1.6e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM24584.1 - 7.2e-06 26.3 0.0 0.0002 21.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 EWM24584.1 - 6.9e-05 22.9 0.0 8.9e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 EWM24584.1 - 0.00011 21.6 0.0 0.00012 21.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EWM24584.1 - 0.00022 20.8 0.0 0.00032 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 EWM24584.1 - 0.001 18.1 0.0 0.0013 17.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_9 PF08003.6 EWM24584.1 - 0.0026 16.5 0.0 0.0033 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_16 PF10294.4 EWM24584.1 - 0.0076 15.7 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_4 PF02390.12 EWM24584.1 - 0.0082 15.2 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Fibrillarin PF01269.12 EWM24584.1 - 0.015 14.2 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin GCD14 PF08704.5 EWM24584.1 - 0.017 14.6 0.0 0.021 14.3 0.0 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_24 PF13578.1 EWM24584.1 - 0.019 15.7 0.0 0.034 14.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EWM24584.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain GidB PF02527.10 EWM24584.1 - 0.13 11.4 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G DNA_topoisoIV PF00521.15 EWM24585.1 - 1.1e-122 409.9 0.0 1.6e-122 409.4 0.0 1.2 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EWM24585.1 - 1.3e-33 115.7 0.6 2.7e-33 114.5 0.4 1.5 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 EWM24585.1 - 3.3e-12 46.2 0.0 1.1e-11 44.5 0.0 2.0 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 EWM24585.1 - 1.3e-09 37.7 0.1 3.5e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase JAB PF01398.16 EWM24586.1 - 5.6e-18 64.7 0.0 1.1e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EWM24586.1 - 4.2e-11 42.9 0.0 8.1e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function E1-E2_ATPase PF00122.15 EWM24587.1 - 8.6e-76 253.9 0.1 3.5e-75 251.9 0.1 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EWM24587.1 - 4.8e-44 150.0 0.2 1.1e-43 148.8 0.2 1.7 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EWM24587.1 - 3.6e-30 105.9 0.0 9.2e-29 101.3 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EWM24587.1 - 5.5e-16 57.7 0.4 4e-15 55.0 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EWM24587.1 - 2.7e-13 49.6 0.0 1.6e-12 47.2 0.0 2.2 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EWM24587.1 - 5.6e-13 49.4 0.0 2.9e-12 47.1 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EWM24587.1 - 0.00026 20.6 2.1 0.00026 20.6 1.5 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ribosomal_60s PF00428.14 EWM24587.1 - 0.012 16.0 6.3 0.053 13.9 4.4 2.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF2921 PF11145.3 EWM24587.1 - 0.34 8.5 0.0 0.54 7.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) Transketolase_N PF00456.16 EWM24588.1 - 2.3e-141 470.4 0.1 3.1e-141 469.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EWM24588.1 - 7.4e-43 146.0 0.0 1.4e-42 145.1 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EWM24588.1 - 2.4e-09 37.1 0.0 5.8e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 EWM24588.1 - 0.00029 19.8 0.1 0.0023 16.9 0.1 1.8 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase KfrA_N PF11740.3 EWM24588.1 - 0.47 10.9 3.7 2.9 8.3 2.6 2.1 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term Inositol_P PF00459.20 EWM24589.1 - 4e-57 193.5 0.2 4.7e-57 193.3 0.1 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family DUF2036 PF09724.4 EWM24590.1 - 7.2e-37 127.2 0.0 2.6e-35 122.1 0.0 2.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) HisKA PF00512.20 EWM24591.1 - 0.14 12.1 0.4 1.9 8.5 0.1 2.8 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain bZIP_1 PF00170.16 EWM24592.1 - 7.8e-12 44.9 7.3 7.8e-12 44.9 5.0 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EWM24592.1 - 6e-07 29.1 10.5 6e-07 29.1 7.3 2.2 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 EWM24592.1 - 0.0011 19.2 4.0 0.0011 19.2 2.8 2.0 2 0 0 2 2 2 1 bZIP Maf transcription factor SR-25 PF10500.4 EWM24592.1 - 0.031 13.7 25.2 0.097 12.1 8.6 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein HAUS6_N PF14661.1 EWM24592.1 - 0.15 11.3 6.1 1.1 8.6 0.6 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Vac_Fusion PF02346.11 EWM24592.1 - 6.8 6.1 7.2 2 7.8 3.1 1.6 2 0 0 2 2 2 0 Chordopoxvirus fusion protein Cyclin PF08613.6 EWM24594.1 - 5e-35 121.0 0.2 8.7e-35 120.3 0.1 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EWM24594.1 - 2e-10 40.3 0.1 3.6e-10 39.4 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pex14_N PF04695.8 EWM24594.1 - 1.3 9.1 6.2 0.63 10.0 1.0 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CDC37_N PF03234.9 EWM24595.1 - 1.3e-22 80.9 14.8 1.3e-22 80.9 10.2 2.8 2 2 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 EWM24595.1 - 1.4e-20 73.4 0.1 1.4e-20 73.4 0.0 2.2 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 EWM24595.1 - 1.5e-18 66.4 0.1 1.5e-18 66.4 0.0 2.9 2 2 1 3 3 3 1 Cdc37 C terminal domain RuBisCO_large_N PF02788.11 EWM24595.1 - 0.16 11.6 0.2 0.3 10.7 0.1 1.4 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain SPARC_Ca_bdg PF10591.4 EWM24595.1 - 0.35 10.9 8.8 0.16 11.9 3.2 2.4 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Spore_coat_CotO PF14153.1 EWM24595.1 - 2.3 7.6 11.0 0.69 9.3 4.0 2.2 2 0 0 2 2 2 0 Spore coat protein CotO Lactamase_B PF00753.22 EWM24596.1 - 1.2e-07 31.5 0.0 2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Fer4_13 PF13370.1 EWM24596.1 - 7.5e-07 29.4 0.1 2.1e-06 27.9 0.0 1.8 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_15 PF13459.1 EWM24596.1 - 0.0011 19.4 0.1 0.0029 18.1 0.1 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Lactamase_B_5 PF14597.1 EWM24596.1 - 0.0012 18.2 0.0 0.0036 16.7 0.0 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Fer4_19 PF06902.6 EWM24596.1 - 0.08 12.7 0.2 0.85 9.4 0.1 2.2 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster FYVE PF01363.16 EWM24597.1 - 1.9e-09 37.2 13.3 4.5e-09 36.0 9.2 1.6 1 0 0 1 1 1 1 FYVE zinc finger Nucleoplasmin PF03066.10 EWM24597.1 - 0.019 14.5 5.3 0.031 13.7 3.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin Myc_N PF01056.13 EWM24597.1 - 0.14 11.3 8.3 0.21 10.6 5.7 1.3 1 0 0 1 1 1 0 Myc amino-terminal region COPI_C PF06957.6 EWM24597.1 - 0.27 9.7 1.4 0.53 8.7 0.1 1.9 2 0 0 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus Na_trans_assoc PF06512.8 EWM24597.1 - 1.5 8.7 8.2 2.4 8.0 5.7 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated alpha-hel2 PF14456.1 EWM24597.1 - 2.3 6.9 5.1 0.5 9.0 0.2 1.9 2 0 0 2 2 2 0 Alpha-helical domain 2 BSP_II PF05432.6 EWM24597.1 - 3 7.0 22.0 1.7 7.8 13.9 1.5 1 1 0 1 1 1 0 Bone sialoprotein II (BSP-II) Nop14 PF04147.7 EWM24597.1 - 5.6 4.7 9.1 7.3 4.3 6.3 1.1 1 0 0 1 1 1 0 Nop14-like family Radial_spoke PF04712.7 EWM24597.1 - 9.1 4.9 11.7 13 4.4 8.1 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein ERCC4 PF02732.10 EWM24598.1 - 3.2e-19 69.0 0.0 6.6e-19 68.0 0.0 1.5 2 0 0 2 2 2 1 ERCC4 domain RPA_interact_N PF14766.1 EWM24599.1 - 4.3e-06 26.0 0.1 9e-06 25.0 0.1 1.5 1 0 0 1 1 1 1 Replication protein A interacting N-terminal RPA_interact_C PF14768.1 EWM24599.1 - 0.0033 17.8 0.6 0.0084 16.4 0.4 1.7 1 0 0 1 1 1 1 Replication protein A interacting C-terminal Methyltransf_11 PF08241.7 EWM24600.1 - 4e-20 72.0 0.0 8.9e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EWM24600.1 - 7.3e-15 54.7 0.0 5e-14 51.9 0.0 2.2 2 1 1 3 3 3 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 EWM24600.1 - 7.2e-13 48.5 0.0 1.3e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM24600.1 - 1.9e-12 46.9 0.0 3.1e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM24600.1 - 2.2e-12 47.2 0.0 3.9e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM24600.1 - 8.7e-12 45.2 0.0 1.8e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM24600.1 - 2.9e-11 43.9 0.0 5.4e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM24600.1 - 2.9e-07 30.5 0.0 1.4e-06 28.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EWM24600.1 - 0.00045 19.9 0.0 0.0062 16.1 0.0 2.2 1 1 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.9 EWM24600.1 - 0.0025 17.2 0.0 0.0043 16.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EWM24600.1 - 0.042 13.3 0.0 0.065 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) HLH PF00010.21 EWM24601.1 - 4.2e-05 23.1 1.0 0.00011 21.7 0.7 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Josephin PF02099.12 EWM24601.1 - 0.025 14.2 0.3 0.043 13.4 0.2 1.3 1 0 0 1 1 1 0 Josephin DUF1948 PF09185.5 EWM24601.1 - 0.088 12.4 0.9 0.14 11.7 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1948) SKIP_SNW PF02731.10 EWM24601.1 - 0.12 11.8 4.9 0.22 10.9 3.4 1.4 1 0 0 1 1 1 0 SKIP/SNW domain Atg14 PF10186.4 EWM24601.1 - 0.85 8.5 5.6 1.2 8.0 3.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 RR_TM4-6 PF06459.7 EWM24601.1 - 8.7 6.1 10.6 7 6.4 6.5 1.4 1 1 0 1 1 1 0 Ryanodine Receptor TM 4-6 JAB PF01398.16 EWM24603.1 - 2e-15 56.5 0.0 3.5e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 EWM24603.1 - 1.7e-10 40.8 0.1 2.9e-10 40.0 0.1 1.2 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.1 EWM24603.1 - 1.1e-05 24.9 0.0 2.5e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain O-FucT PF10250.4 EWM24604.1 - 9.5e-06 24.9 1.3 0.0013 17.9 0.5 3.4 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase BolA PF01722.13 EWM24605.1 - 9.3e-29 99.2 0.6 1.2e-28 98.8 0.4 1.2 1 0 0 1 1 1 1 BolA-like protein Lipase_3 PF01764.20 EWM24606.1 - 1e-18 67.3 0.0 1.7e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) FYVE PF01363.16 EWM24606.1 - 1.8e-12 46.9 10.6 3.5e-12 46.0 7.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger Abhydrolase_3 PF07859.8 EWM24606.1 - 0.014 14.9 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold zf-AN1 PF01428.11 EWM24606.1 - 0.13 12.1 10.3 0.38 10.6 7.2 1.8 1 0 0 1 1 1 0 AN1-like Zinc finger ABC2_membrane PF01061.19 EWM24607.1 - 1.1e-27 96.5 23.3 1.7e-27 95.9 16.1 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EWM24607.1 - 3.6e-24 85.6 0.0 6e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EWM24607.1 - 7.4e-08 32.6 0.3 0.0081 16.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 EWM24607.1 - 0.00011 21.3 26.7 0.00011 21.3 18.5 1.9 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_16 PF13191.1 EWM24607.1 - 0.00067 19.6 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EWM24607.1 - 0.0078 15.4 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EWM24607.1 - 0.013 14.9 0.0 0.027 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EWM24607.1 - 0.023 14.8 0.0 0.065 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 EWM24607.1 - 0.038 13.1 0.0 0.2 10.8 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Arch_ATPase PF01637.13 EWM24607.1 - 0.04 13.6 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase PduV-EutP PF10662.4 EWM24607.1 - 0.047 13.1 0.2 0.27 10.7 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 EWM24607.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EWM24607.1 - 0.17 12.0 0.0 0.5 10.5 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2628 PF10947.3 EWM24607.1 - 4.6 7.0 8.0 1.3 8.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) Cpn60_TCP1 PF00118.19 EWM24608.1 - 9.8e-124 413.6 11.8 1.1e-123 413.4 8.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.19 EWM24609.1 - 9.8e-124 413.6 11.8 1.1e-123 413.4 8.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DNA_gyraseB PF00204.20 EWM24610.1 - 2.1e-52 176.8 0.0 3.3e-52 176.2 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase B DNA_gyraseB_C PF00986.16 EWM24610.1 - 2.7e-29 100.6 1.4 5e-28 96.6 0.1 2.6 2 0 0 2 2 2 1 DNA gyrase B subunit, carboxyl terminus Toprim PF01751.17 EWM24610.1 - 1.2e-24 86.1 0.0 2.9e-24 84.9 0.0 1.7 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 EWM24610.1 - 1.4e-15 56.9 0.2 2.8e-15 56.0 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EWM24610.1 - 0.00025 20.7 0.0 0.0005 19.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim_4 PF13662.1 EWM24610.1 - 0.041 13.8 0.1 0.71 9.9 0.0 2.5 2 0 0 2 2 2 0 Toprim domain Abhydrolase_6 PF12697.2 EWM24611.1 - 4.5e-15 56.1 0.4 9.6e-15 55.0 0.2 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM24611.1 - 4.3e-11 42.7 0.0 1.1e-10 41.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EWM24611.1 - 4.3e-09 36.2 0.1 2.2e-05 24.1 0.1 2.2 1 1 1 2 2 2 2 PGAP1-like protein Abhydrolase_1 PF00561.15 EWM24611.1 - 6.2e-08 32.4 0.0 1.4e-07 31.3 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF915 PF06028.6 EWM24611.1 - 0.0001 21.5 0.0 0.049 12.7 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) DLH PF01738.13 EWM24611.1 - 0.00022 20.5 0.0 0.098 11.9 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family LCAT PF02450.10 EWM24611.1 - 0.015 14.3 0.1 0.024 13.5 0.1 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.3 EWM24611.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase UDPG_MGDP_dh_N PF03721.9 EWM24612.1 - 1.6e-53 180.8 0.3 2.5e-53 180.1 0.2 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 EWM24612.1 - 1.7e-33 114.9 0.1 1.2e-32 112.2 0.0 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 EWM24612.1 - 2.4e-33 114.2 0.0 4.6e-33 113.3 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain Peptidase_C13 PF01650.13 EWM24613.1 - 3.6e-42 144.4 0.0 5.2e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C13 PF01650.13 EWM24614.1 - 5.1e-30 104.6 0.0 7.3e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family SecY PF00344.15 EWM24615.1 - 4e-95 318.6 13.9 5.5e-95 318.2 9.6 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EWM24615.1 - 6.7e-20 70.3 0.1 2e-19 68.7 0.1 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p DEAD PF00270.24 EWM24618.1 - 2.5e-44 150.7 0.0 9.8e-44 148.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EWM24618.1 - 1.6e-17 63.1 0.0 4.3e-17 61.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 EWM24618.1 - 4.1e-13 48.9 2.2 4.1e-13 48.9 1.5 2.0 2 0 0 2 2 2 1 DBP10CT (NUC160) domain ResIII PF04851.10 EWM24618.1 - 0.00082 19.2 0.0 0.002 17.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit MFS_1 PF07690.11 EWM24619.1 - 3.8e-26 91.6 25.8 3.8e-26 91.6 17.9 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 EWM24619.1 - 2.5e-20 72.0 17.9 1.1e-08 33.5 0.0 4.1 1 1 3 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.19 EWM24619.1 - 1.2e-08 33.9 7.4 1.2e-08 33.9 5.1 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter FKBP_C PF00254.23 EWM24621.1 - 1.9e-15 56.6 0.0 3e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Sds3 PF08598.6 EWM24622.1 - 1.1e-13 51.1 13.6 2.4e-13 50.0 9.4 1.5 1 0 0 1 1 1 1 Sds3-like eIF-5a PF01287.15 EWM24622.1 - 0.00082 19.2 0.0 0.0029 17.5 0.0 1.8 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Terminase_2 PF03592.11 EWM24622.1 - 0.39 10.9 7.3 4.4 7.5 0.4 2.3 1 1 1 2 2 2 0 Terminase small subunit OmpH PF03938.9 EWM24622.1 - 4.5 7.1 9.0 9.5 6.1 6.2 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) EF-hand_7 PF13499.1 EWM24623.1 - 5.2e-20 71.3 0.1 5.5e-17 61.6 0.0 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EWM24623.1 - 2e-09 36.3 0.8 0.014 14.6 0.0 4.0 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EWM24623.1 - 1e-08 34.3 0.3 0.061 13.2 0.0 3.9 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.27 EWM24623.1 - 3.3e-08 32.2 0.0 0.01 15.1 0.0 3.8 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 EWM24623.1 - 7.4e-06 25.4 0.4 0.14 11.7 0.0 3.8 3 1 0 3 3 3 2 EF-hand domain pair RabGAP-TBC PF00566.13 EWM24625.1 - 1.5e-26 93.1 0.0 2.6e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ank_2 PF12796.2 EWM24625.1 - 1e-21 77.0 3.4 4e-17 62.3 0.4 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EWM24625.1 - 4.7e-20 70.3 12.0 8.8e-06 25.2 0.3 5.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 EWM24625.1 - 1.5e-14 53.6 4.4 1.2e-09 38.0 0.5 4.2 2 2 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM24625.1 - 6.3e-14 50.7 5.0 0.00041 20.3 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EWM24625.1 - 7.3e-13 48.6 0.9 0.0013 19.2 0.1 3.8 3 0 0 3 3 3 3 Ankyrin repeats (many copies) PA PF02225.17 EWM24625.1 - 8.7e-09 34.9 0.0 2.3e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 PA domain DUF1275 PF06912.6 EWM24625.1 - 3.4 6.7 7.0 3.2 6.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1275) PAP_fibrillin PF04755.7 EWM24627.1 - 9.9e-11 41.7 0.0 1.5e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 PAP_fibrillin EF-hand_7 PF13499.1 EWM24628.1 - 7.2e-07 29.2 0.7 0.15 12.2 0.0 4.3 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.27 EWM24628.1 - 0.0014 17.7 0.9 5.3 6.5 0.0 4.8 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.1 EWM24628.1 - 0.02 14.7 0.1 29 4.8 0.0 4.5 4 0 0 4 4 4 0 EF-hand domain DUF1275 PF06912.6 EWM24629.1 - 2.5e-34 118.3 17.1 3.4e-34 117.9 11.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) WD40 PF00400.27 EWM24630.1 - 2e-38 128.9 9.5 7.6e-11 41.4 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EWM24630.1 - 6.3e-05 21.9 0.0 0.0046 15.7 0.0 2.5 1 1 0 2 2 2 2 Nup133 N terminal like eIF2A PF08662.6 EWM24630.1 - 0.0048 16.6 0.0 9.9 5.8 0.0 3.5 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Transket_pyr PF02779.19 EWM24631.1 - 6.3e-66 221.2 0.0 1.2e-65 220.3 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EWM24631.1 - 1.1e-56 191.8 0.0 1.7e-56 191.1 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Sad1_UNC PF07738.8 EWM24632.1 - 3.9e-26 91.4 0.0 7.1e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal F5_F8_type_C PF00754.20 EWM24632.1 - 1e-05 25.3 0.0 2.3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain rve PF00665.21 EWM24634.1 - 3e-17 62.8 0.0 4.6e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain MIF4G PF02854.14 EWM24635.1 - 3.4e-41 140.9 4.9 5.2e-41 140.3 3.4 1.3 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 EWM24635.1 - 1.5e-05 24.6 0.1 5.2e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 MA3 domain zf-RING_2 PF13639.1 EWM24636.1 - 2.5e-08 33.6 13.1 1.1e-07 31.6 9.1 2.2 1 0 0 1 1 1 1 Ring finger domain Atx10homo_assoc PF09759.4 EWM24636.1 - 3.6e-07 29.8 5.6 0.029 14.1 0.0 5.9 5 1 1 6 6 6 2 Spinocerebellar ataxia type 10 protein domain zf-rbx1 PF12678.2 EWM24636.1 - 2.7e-05 24.1 7.2 0.00011 22.2 5.0 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger Arm PF00514.18 EWM24636.1 - 0.0012 18.5 3.9 4 7.4 0.0 7.3 8 1 0 8 8 8 1 Armadillo/beta-catenin-like repeat zf-C3HC4_3 PF13920.1 EWM24636.1 - 0.0018 17.9 8.7 0.0063 16.1 6.1 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EWM24636.1 - 0.0029 17.5 13.1 0.011 15.7 9.0 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) WAPL PF07814.8 EWM24636.1 - 0.0083 14.8 6.6 3.1 6.4 0.0 4.4 4 1 0 5 5 5 3 Wings apart-like protein regulation of heterochromatin RINGv PF12906.2 EWM24636.1 - 1.2 9.1 12.7 3.7 7.6 8.8 1.9 1 0 0 1 1 1 0 RING-variant domain TRAPP PF04051.11 EWM24637.1 - 1.1e-39 135.3 0.0 1.3e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Ala_racemase_N PF01168.15 EWM24638.1 - 3.7e-43 147.6 0.8 4.5e-43 147.3 0.5 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain HLH PF00010.21 EWM24640.1 - 4.5e-05 23.0 0.6 9.3e-05 22.0 0.4 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TFIIA PF03153.8 EWM24640.1 - 0.21 11.4 12.5 0.41 10.4 8.6 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 EWM24640.1 - 0.24 9.5 27.5 0.32 9.1 19.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RCR PF12273.3 EWM24640.1 - 5.9 7.4 19.4 14 6.2 13.4 1.6 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Flu_M1 PF00598.14 EWM24642.1 - 0.097 12.0 0.2 0.44 9.9 0.1 2.0 2 0 0 2 2 2 0 Influenza Matrix protein (M1) DUF4524 PF15025.1 EWM24643.1 - 0.097 12.1 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4524) Exo_endo_phos PF03372.18 EWM24644.1 - 5.4e-14 52.7 0.0 1.7e-13 51.1 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EWM24644.1 - 2.7e-05 23.7 0.0 0.089 12.4 0.0 2.4 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase zf-GRF PF06839.7 EWM24644.1 - 0.0016 18.2 0.6 0.0016 18.2 0.4 2.1 2 0 0 2 2 2 1 GRF zinc finger V-SNARE_C PF12352.3 EWM24646.1 - 4e-12 46.0 1.7 2.6e-11 43.4 0.7 2.0 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EWM24646.1 - 0.01 15.5 0.0 0.039 13.6 0.0 1.8 2 0 0 2 2 2 0 Sec20 Pkinase PF00069.20 EWM24647.1 - 9.7e-51 172.4 0.0 9.9e-31 106.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EWM24647.1 - 1.3e-22 80.1 0.0 5.9e-15 55.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EWM24647.1 - 0.00028 19.9 0.0 1.1 8.1 0.0 3.1 3 0 0 3 3 3 2 Kinase-like PH PF00169.24 EWM24647.1 - 0.00056 20.0 0.0 0.0064 16.6 0.0 2.2 1 1 0 1 1 1 1 PH domain Kdo PF06293.9 EWM24647.1 - 0.0071 15.4 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EWM24647.1 - 0.12 11.6 0.0 2.2 7.5 0.0 2.3 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Methyltransf_11 PF08241.7 EWM24648.1 - 1.5e-12 47.8 0.0 2.3e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM24648.1 - 7.3e-09 35.3 0.0 9.6e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM24648.1 - 6.9e-06 26.6 0.0 1.1e-05 25.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM24648.1 - 0.00054 20.3 0.0 0.001 19.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM24648.1 - 0.00064 19.4 0.0 0.00099 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EWM24648.1 - 0.012 14.7 0.0 0.023 13.8 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TPMT PF05724.6 EWM24648.1 - 0.015 14.7 0.0 0.03 13.7 0.0 1.5 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) BPL_LplA_LipB PF03099.14 EWM24649.1 - 1.7e-10 41.0 0.0 2.5e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family NPR3 PF03666.8 EWM24650.1 - 8e-37 126.8 0.0 7.7e-31 107.1 0.0 3.2 2 1 0 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 GTPase_Cys_C PF12631.2 EWM24652.1 - 0.32 11.4 2.5 8.8 6.8 0.0 3.5 3 0 0 3 3 3 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE DNA_ligase_A_M PF01068.16 EWM24654.1 - 1.8e-55 187.4 0.0 1.1e-54 184.8 0.0 2.0 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EWM24654.1 - 1.7e-35 122.4 0.0 7.2e-35 120.3 0.0 2.0 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EWM24654.1 - 1.2e-23 83.3 0.0 2.9e-22 78.8 0.0 2.5 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 EWM24654.1 - 0.045 13.4 0.3 1.7 8.3 0.0 2.6 2 0 0 2 2 2 0 DNA ligase OB-like domain RVT_2 PF07727.9 EWM24655.1 - 1.9e-83 279.2 0.0 2.5e-83 278.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C3HC4_2 PF13923.1 EWM24656.1 - 2.8e-11 43.2 9.3 5.1e-11 42.4 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EWM24656.1 - 9.8e-10 38.1 9.9 1.8e-09 37.2 6.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EWM24656.1 - 1.4e-09 37.4 4.2 2.8e-09 36.5 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EWM24656.1 - 7.5e-09 35.1 5.6 1.4e-08 34.3 3.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EWM24656.1 - 1.6e-08 34.0 6.8 3.3e-08 33.0 4.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EWM24656.1 - 8.5e-05 22.1 4.3 0.00093 18.8 0.8 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 EWM24656.1 - 0.00013 21.9 5.3 0.00028 20.9 3.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EWM24656.1 - 0.00052 19.8 9.5 0.00094 19.0 6.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Rtf2 PF04641.7 EWM24656.1 - 0.021 14.0 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Patatin PF01734.17 EWM24657.1 - 5.1e-15 55.9 0.0 1.1e-14 54.8 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase Tmemb_cc2 PF10267.4 EWM24657.1 - 0.07 11.7 0.5 0.12 10.9 0.1 1.6 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein DivIC PF04977.10 EWM24657.1 - 0.12 11.9 0.5 0.21 11.0 0.4 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF3336 PF11815.3 EWM24658.1 - 6.6e-21 74.3 0.2 1.4e-20 73.2 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EWM24658.1 - 1.2e-20 74.3 0.0 2.7e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase DivIC PF04977.10 EWM24658.1 - 0.098 12.1 0.5 0.29 10.6 0.4 1.7 1 0 0 1 1 1 0 Septum formation initiator Ras PF00071.17 EWM24659.1 - 0.00087 18.7 0.0 0.002 17.5 0.0 1.5 2 0 0 2 2 2 1 Ras family Miro PF08477.8 EWM24659.1 - 0.0012 19.2 0.0 0.0037 17.7 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein DAP3 PF10236.4 EWM24659.1 - 0.032 13.1 0.2 0.054 12.4 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Arf PF00025.16 EWM24659.1 - 0.092 11.9 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family VirE PF05272.6 EWM24659.1 - 0.21 11.0 0.0 0.36 10.2 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E TPR_11 PF13414.1 EWM24660.1 - 4e-12 45.6 3.0 3.4e-11 42.6 0.6 2.5 2 0 0 2 2 2 1 TPR repeat WD40 PF00400.27 EWM24660.1 - 3.5e-09 36.2 9.3 1.2e-05 24.9 0.2 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat TPR_16 PF13432.1 EWM24660.1 - 4.1e-07 30.4 0.5 1.1e-06 29.1 0.4 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EWM24660.1 - 2.7e-06 26.7 7.0 0.0028 17.1 0.0 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EWM24660.1 - 7.3e-06 25.5 1.0 0.1 12.5 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EWM24660.1 - 0.0089 15.7 0.0 0.026 14.3 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 EWM24660.1 - 0.017 15.3 0.8 0.79 10.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 EWM24660.1 - 0.029 14.5 0.4 0.053 13.6 0.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EWM24660.1 - 0.044 14.4 0.3 4.1 8.3 0.1 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF627 PF04781.7 EWM24660.1 - 0.16 11.6 0.2 0.31 10.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF627) TPR_8 PF13181.1 EWM24660.1 - 1.4 8.8 4.1 6.2 6.8 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DcpS_C PF11969.3 EWM24661.1 - 7.5e-21 74.5 0.1 1e-20 74.0 0.1 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EWM24661.1 - 2.7e-06 27.8 0.2 5e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 HIT domain NAP PF00956.13 EWM24661.1 - 0.011 14.8 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) Peptidase_C69 PF03577.10 EWM24662.1 - 8.8e-50 169.7 0.0 1.1e-49 169.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C69 MucB_RseB PF03888.9 EWM24662.1 - 0.096 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 MucB/RseB family Peptidase_C69 PF03577.10 EWM24663.1 - 5.7e-61 206.5 0.0 2.4e-60 204.5 0.0 1.8 1 1 0 2 2 2 1 Peptidase family C69 MucB_RseB PF03888.9 EWM24663.1 - 0.075 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 MucB/RseB family Amidase PF01425.16 EWM24666.1 - 1.7e-127 425.9 2.7 2e-127 425.6 1.9 1.1 1 0 0 1 1 1 1 Amidase DUF3172 PF11371.3 EWM24667.1 - 3.2e-50 169.2 0.2 4.3e-50 168.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3172) PBP1_TM PF14812.1 EWM24667.1 - 3 8.2 7.0 6.2 7.2 4.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ABC2_membrane PF01061.19 EWM24668.1 - 2.4e-24 85.6 28.4 4.5e-24 84.7 19.7 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EWM24668.1 - 2.4e-19 69.9 0.0 3.7e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EWM24668.1 - 2.4e-08 34.2 0.1 4.3e-07 30.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 EWM24668.1 - 0.00028 20.0 23.7 0.00028 20.0 16.4 1.9 1 1 0 2 2 2 1 ABC-2 family transporter protein AAA_22 PF13401.1 EWM24668.1 - 0.00072 19.7 0.0 0.64 10.1 0.0 2.8 1 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 EWM24668.1 - 0.0039 16.4 0.0 0.0063 15.7 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 EWM24668.1 - 0.05 13.5 0.1 0.45 10.4 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EWM24668.1 - 0.063 13.6 0.6 0.092 13.0 0.1 1.5 2 0 0 2 2 2 0 AAA domain CCT PF06203.9 EWM24669.1 - 3.1e-14 52.3 12.3 4.6e-14 51.7 8.5 1.2 1 0 0 1 1 1 1 CCT motif PAP_fibrillin PF04755.7 EWM24670.1 - 1.8e-10 40.8 0.0 2e-09 37.4 0.0 2.1 1 1 0 1 1 1 1 PAP_fibrillin SipA PF09052.5 EWM24670.1 - 0.064 11.6 1.9 0.081 11.3 1.3 1.1 1 0 0 1 1 1 0 Salmonella invasion protein A RRM_1 PF00076.17 EWM24674.1 - 1.4e-21 75.8 0.0 1.9e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM24674.1 - 6.9e-16 57.9 0.0 9.8e-16 57.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM24674.1 - 7.3e-10 38.5 0.0 1.2e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Y_phosphatase3 PF13350.1 EWM24675.1 - 0.0046 17.2 0.0 0.0099 16.1 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family IpgD PF05925.7 EWM24675.1 - 0.2 9.8 0.1 0.43 8.7 0.0 1.5 2 0 0 2 2 2 0 Enterobacterial virulence protein IpgD Histone PF00125.19 EWM24676.1 - 1.4e-13 50.7 0.1 1.7e-13 50.4 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EWM24676.1 - 7.7e-05 22.7 0.0 0.0001 22.3 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EWM24676.1 - 0.00072 19.4 0.1 0.00098 19.0 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EWM24676.1 - 0.0028 17.6 0.0 0.0045 17.0 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EWM24676.1 - 0.062 13.0 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.10 EWM24676.1 - 0.066 12.9 0.0 0.081 12.7 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CENP-T PF15511.1 EWM24676.1 - 0.083 12.1 0.0 0.083 12.1 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T NAD_binding_8 PF13450.1 EWM24677.1 - 2.1e-13 50.0 0.3 8.2e-13 48.1 0.2 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EWM24677.1 - 6.3e-11 41.7 7.7 1.8e-05 23.8 0.2 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EWM24677.1 - 3.7e-09 35.9 3.9 3.7e-07 29.3 2.7 2.8 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EWM24677.1 - 4.7e-05 22.5 0.5 0.0002 20.5 0.1 1.9 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EWM24677.1 - 0.0005 18.6 0.1 0.17 10.3 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 EWM24677.1 - 0.00065 19.6 0.6 0.0011 18.8 0.4 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 EWM24677.1 - 0.0015 17.7 0.1 0.0025 17.0 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EWM24677.1 - 0.0047 15.9 0.5 0.34 9.7 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.2 EWM24677.1 - 0.0058 15.7 2.4 0.0058 15.7 1.7 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase MFS_1 PF07690.11 EWM24677.1 - 0.013 14.2 0.2 0.031 13.0 0.1 1.6 1 0 0 1 1 1 0 Major Facilitator Superfamily GDI PF00996.13 EWM24677.1 - 0.055 11.7 0.3 2.4 6.3 0.1 2.0 2 0 0 2 2 2 0 GDP dissociation inhibitor FAD_binding_3 PF01494.14 EWM24677.1 - 0.061 12.3 0.5 0.097 11.6 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain SNARE_assoc PF09335.6 EWM24678.1 - 6e-22 78.1 6.7 6e-22 78.1 4.6 2.0 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF456 PF04306.8 EWM24678.1 - 0.82 9.6 20.3 0.15 12.1 1.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF456) RNase_H2_suC PF08615.6 EWM24680.1 - 1.3e-11 44.5 0.0 1.5e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Ead_Ea22 PF13935.1 EWM24681.1 - 0.00042 20.6 2.0 1.1 9.6 0.0 2.6 2 0 0 2 2 2 2 Ead/Ea22-like protein MSA-2c PF12238.3 EWM24681.1 - 0.016 14.9 0.3 0.042 13.5 0.2 1.7 1 0 0 1 1 1 0 Merozoite surface antigen 2c EMP24_GP25L PF01105.19 EWM24681.1 - 0.031 13.9 0.3 0.098 12.3 0.0 2.0 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF3373 PF11853.3 EWM24681.1 - 0.086 11.3 2.2 0.17 10.4 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Peptidase_S24 PF00717.18 EWM24682.1 - 6.5e-13 48.1 0.0 1e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EWM24682.1 - 2.5e-05 23.7 0.0 0.008 15.7 0.0 2.8 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Pkinase PF00069.20 EWM24683.1 - 4.1e-53 180.1 0.0 1.7e-52 178.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM24683.1 - 1.9e-36 125.4 0.0 2.7e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EWM24683.1 - 8.9e-06 24.8 0.0 0.00045 19.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like UbiA PF01040.13 EWM24684.1 - 9.3e-35 120.0 14.7 1.2e-34 119.7 10.2 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Histone PF00125.19 EWM24685.1 - 8.1e-32 109.1 0.2 1.2e-31 108.5 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EWM24685.1 - 0.00012 22.2 0.0 0.00018 21.6 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EWM24685.1 - 0.02 14.9 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone EMP70 PF02990.11 EWM24686.1 - 1.6e-197 657.1 5.9 2.2e-197 656.6 4.1 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 zf-RanBP PF00641.13 EWM24688.1 - 2.6e-08 32.7 6.1 3.9e-08 32.2 4.2 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others WW PF00397.21 EWM24688.1 - 1.1e-07 31.5 6.0 2.2e-07 30.5 4.1 1.5 1 0 0 1 1 1 1 WW domain DZR PF12773.2 EWM24688.1 - 0.037 13.8 0.7 0.056 13.2 0.5 1.2 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 EWM24688.1 - 0.69 9.2 4.6 1.1 8.5 3.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain IBR PF01485.16 EWM24689.1 - 4.3e-14 52.1 21.9 1.1e-07 31.6 9.2 2.3 1 1 1 2 2 2 2 IBR domain Biotin_lipoyl PF00364.17 EWM24690.1 - 8.6e-17 60.5 4.1 1.2e-16 60.1 2.8 1.2 1 0 0 1 1 1 1 Biotin-requiring enzyme GCV_H PF01597.14 EWM24690.1 - 0.036 13.7 0.7 0.051 13.2 0.5 1.2 1 0 0 1 1 1 0 Glycine cleavage H-protein Biotin_lipoyl_2 PF13533.1 EWM24690.1 - 0.054 13.1 1.9 0.094 12.3 0.2 2.0 1 1 1 2 2 2 0 Biotin-lipoyl like DUF2360 PF10152.4 EWM24690.1 - 0.77 10.0 3.8 1.3 9.3 2.6 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Ufd2P_core PF10408.4 EWM24691.1 - 2.2e-61 207.9 0.0 2.7e-61 207.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EWM24691.1 - 2.1e-26 91.6 0.2 8.5e-26 89.7 0.1 2.0 2 0 0 2 2 2 1 U-box domain Arc PF03869.9 EWM24691.1 - 0.042 13.4 0.3 0.54 9.9 0.2 2.5 2 0 0 2 2 2 0 Arc-like DNA binding domain Chlor_dismutase PF06778.7 EWM24691.1 - 0.13 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Chlorite dismutase DUF948 PF06103.6 EWM24691.1 - 0.15 11.9 0.0 0.43 10.4 0.0 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ABC_tran PF00005.22 EWM24693.1 - 2e-12 47.5 0.0 7.7e-12 45.6 0.0 2.0 1 1 0 1 1 1 1 ABC transporter HEAT PF02985.17 EWM24693.1 - 4.2e-08 32.6 0.2 0.0043 17.0 0.0 4.8 4 0 0 4 4 4 1 HEAT repeat Ipi1_N PF12333.3 EWM24693.1 - 1.5e-06 28.1 0.0 0.26 11.2 0.0 3.4 2 1 1 3 3 3 2 Rix1 complex component involved in 60S ribosome maturation HEAT_2 PF13646.1 EWM24693.1 - 4.9e-06 26.7 0.7 0.0039 17.4 0.0 2.9 2 1 1 3 3 3 1 HEAT repeats AAA_21 PF13304.1 EWM24693.1 - 5.9e-05 23.1 0.0 0.001 19.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain HEAT_EZ PF13513.1 EWM24693.1 - 0.00089 19.6 6.0 1.6 9.2 0.0 5.2 6 0 0 6 6 6 1 HEAT-like repeat Cnd1 PF12717.2 EWM24693.1 - 0.0031 17.3 0.1 0.011 15.6 0.1 2.0 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Arch_ATPase PF01637.13 EWM24693.1 - 0.0039 16.9 0.0 0.0094 15.6 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase Adaptin_N PF01602.15 EWM24693.1 - 0.007 14.7 0.6 0.016 13.5 0.2 1.5 1 1 0 1 1 1 1 Adaptin N terminal region DUF2454 PF10521.4 EWM24693.1 - 0.018 14.0 0.1 0.049 12.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2454) AAA_15 PF13175.1 EWM24693.1 - 0.02 13.9 0.0 0.31 10.0 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain Vac14_Fab1_bd PF12755.2 EWM24693.1 - 0.033 14.5 0.1 0.21 12.0 0.0 2.3 1 1 0 2 2 2 0 Vacuolar 14 Fab1-binding region MMR_HSR1 PF01926.18 EWM24693.1 - 0.034 14.1 0.0 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.1 EWM24693.1 - 0.035 14.0 0.0 0.34 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EWM24693.1 - 0.046 13.2 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF1981 PF09324.5 EWM24693.1 - 0.052 13.0 0.5 0.31 10.6 0.0 2.4 3 0 0 3 3 2 0 Domain of unknown function (DUF1981) AAA_23 PF13476.1 EWM24693.1 - 0.071 13.4 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EWM24693.1 - 0.081 13.1 0.0 0.51 10.5 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF326 PF03860.11 EWM24693.1 - 9.4 6.2 7.2 4.1 7.3 0.3 2.9 3 0 0 3 3 2 0 Domain of Unknown Function (DUF326) DUF2088 PF09861.4 EWM24694.1 - 3.3e-14 52.4 0.0 4.6e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2088) ABC_tran PF00005.22 EWM24696.1 - 5.8e-24 84.9 0.1 3.5e-22 79.1 0.0 2.9 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EWM24696.1 - 3.4e-08 33.7 0.0 5.5e-07 29.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain Chromo PF00385.19 EWM24696.1 - 2.3e-07 30.3 0.8 5.4e-07 29.1 0.5 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SMC_N PF02463.14 EWM24696.1 - 2.4e-07 30.1 1.3 1e-06 28.1 0.1 2.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EWM24696.1 - 0.0016 19.2 1.5 0.0077 17.0 0.0 2.6 2 2 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EWM24696.1 - 0.0018 18.1 0.0 0.0059 16.4 0.0 1.8 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EWM24696.1 - 0.008 15.6 0.1 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Miro PF08477.8 EWM24696.1 - 0.013 16.0 0.1 0.044 14.2 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein DUF258 PF03193.11 EWM24696.1 - 0.021 13.9 0.0 0.053 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF87 PF01935.12 EWM24696.1 - 0.026 14.3 0.0 0.026 14.3 0.0 2.7 3 1 0 3 3 3 0 Domain of unknown function DUF87 AAA_22 PF13401.1 EWM24696.1 - 0.029 14.5 0.0 0.3 11.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EWM24696.1 - 0.034 13.8 0.4 0.14 11.8 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EWM24696.1 - 0.035 13.9 1.0 0.13 12.0 0.0 2.3 2 0 0 2 2 2 0 Dynamin family MMR_HSR1 PF01926.18 EWM24696.1 - 0.053 13.4 0.1 0.17 11.8 0.0 2.0 2 0 0 2 2 1 0 50S ribosome-binding GTPase AAA_30 PF13604.1 EWM24696.1 - 0.056 13.0 0.2 3.6 7.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EWM24696.1 - 0.062 13.1 0.0 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EWM24696.1 - 0.072 13.2 0.0 0.8 9.9 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EWM24696.1 - 0.081 12.3 1.1 0.29 10.5 0.0 2.2 2 1 0 2 2 2 0 AAA-like domain AAA_16 PF13191.1 EWM24696.1 - 0.094 12.6 0.0 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain ArgK PF03308.11 EWM24696.1 - 0.17 10.6 0.1 0.17 10.6 0.1 1.7 2 0 0 2 2 2 0 ArgK protein AAA_18 PF13238.1 EWM24696.1 - 0.3 11.4 4.1 0.85 9.9 0.0 3.0 2 2 0 2 2 2 0 AAA domain Daxx PF03344.10 EWM24697.1 - 0.00022 19.8 13.2 0.00035 19.2 9.2 1.4 1 0 0 1 1 1 1 Daxx Family FLO_LFY PF01698.11 EWM24697.1 - 0.015 14.1 8.5 0.029 13.2 5.9 1.5 1 0 0 1 1 1 0 Floricaula / Leafy protein CobT PF06213.7 EWM24697.1 - 0.031 13.4 13.6 0.047 12.8 9.4 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ycf1 PF05758.7 EWM24697.1 - 0.073 10.7 8.4 0.089 10.5 5.8 1.1 1 0 0 1 1 1 0 Ycf1 SAPS PF04499.10 EWM24697.1 - 0.18 10.4 5.0 0.24 9.9 3.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.9 EWM24697.1 - 1 7.3 14.8 1.5 6.7 10.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.17 EWM24697.1 - 2.1 7.2 4.4 3.9 6.4 3.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Nop14 PF04147.7 EWM24697.1 - 5.7 4.7 22.4 8.7 4.1 15.5 1.2 1 0 0 1 1 1 0 Nop14-like family DUF605 PF04652.11 EWM24697.1 - 6 6.1 21.3 0.33 10.3 10.0 2.0 1 1 0 2 2 2 0 Vta1 like Daxx PF03344.10 EWM24698.1 - 0.00022 19.8 13.2 0.00035 19.2 9.2 1.4 1 0 0 1 1 1 1 Daxx Family FLO_LFY PF01698.11 EWM24698.1 - 0.015 14.1 8.5 0.029 13.2 5.9 1.5 1 0 0 1 1 1 0 Floricaula / Leafy protein CobT PF06213.7 EWM24698.1 - 0.031 13.4 13.6 0.047 12.8 9.4 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ycf1 PF05758.7 EWM24698.1 - 0.073 10.7 8.4 0.089 10.5 5.8 1.1 1 0 0 1 1 1 0 Ycf1 SAPS PF04499.10 EWM24698.1 - 0.18 10.4 5.0 0.24 9.9 3.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.9 EWM24698.1 - 1 7.3 14.8 1.5 6.7 10.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.17 EWM24698.1 - 2.1 7.2 4.4 3.9 6.4 3.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Nop14 PF04147.7 EWM24698.1 - 5.7 4.7 22.4 8.7 4.1 15.5 1.2 1 0 0 1 1 1 0 Nop14-like family DUF605 PF04652.11 EWM24698.1 - 6 6.1 21.3 0.33 10.3 10.0 2.0 1 1 0 2 2 2 0 Vta1 like MbeD_MobD PF04899.7 EWM24699.1 - 0.015 15.1 0.4 0.034 14.0 0.3 1.6 1 0 0 1 1 1 0 MbeD/MobD like B_lectin PF01453.19 EWM24699.1 - 0.057 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 D-mannose binding lectin DUF16 PF01519.11 EWM24699.1 - 0.57 10.4 2.5 0.93 9.7 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 DivIC PF04977.10 EWM24699.1 - 0.82 9.2 5.0 0.47 9.9 0.4 2.3 1 1 1 2 2 2 0 Septum formation initiator Sec2p PF06428.6 EWM24699.1 - 1.5 8.7 8.1 1.3 8.8 0.4 2.2 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p DNA_mis_repair PF01119.14 EWM24700.1 - 3.1e-27 94.4 0.0 5.3e-27 93.6 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EWM24700.1 - 1.9e-11 43.7 0.0 3.6e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EWM24700.1 - 1.4e-10 40.8 0.0 3.5e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CAP_N PF01213.14 EWM24701.1 - 5.2e-50 170.5 5.1 5.2e-50 170.5 3.5 1.7 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EWM24701.1 - 1.3e-43 148.1 0.0 2.3e-43 147.3 0.0 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Ribosomal_60s PF00428.14 EWM24701.1 - 0.04 14.3 0.5 0.17 12.3 0.0 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein TBCC PF07986.7 EWM24701.1 - 0.049 13.0 0.2 0.093 12.1 0.1 1.4 1 0 0 1 1 1 0 Tubulin binding cofactor C RNA_lig_T4_1 PF09511.5 EWM24701.1 - 0.1 12.0 0.0 0.32 10.4 0.0 1.8 1 1 0 1 1 1 0 RNA ligase PsbU PF06514.6 EWM24702.1 - 3.9e-37 125.9 0.1 5.7e-37 125.4 0.0 1.2 1 0 0 1 1 1 1 Photosystem II 12 kDa extrinsic protein (PsbU) HHH_3 PF12836.2 EWM24702.1 - 8.8e-07 28.7 0.0 1.4e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix motif SAP PF02037.22 EWM24703.1 - 1.6e-11 43.3 0.5 4.1e-11 42.1 0.3 1.7 1 0 0 1 1 1 1 SAP domain INCENP_ARK-bind PF03941.10 EWM24703.1 - 5e-08 32.6 0.0 5e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region HeH PF12949.2 EWM24703.1 - 0.011 15.3 1.7 0.02 14.4 0.1 2.2 2 0 0 2 2 2 0 HeH/LEM domain Pkinase PF00069.20 EWM24704.1 - 3.4e-33 114.8 0.0 2.3e-32 112.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM24704.1 - 1.1e-08 34.4 0.0 0.0022 17.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 EWM24704.1 - 0.00017 20.7 0.0 0.00027 20.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EWM24704.1 - 0.04 13.6 0.1 0.089 12.5 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Involucrin_N PF10583.4 EWM24704.1 - 1.1 9.6 7.7 13 6.2 0.1 3.1 3 0 0 3 3 3 0 Involucrin of squamous epithelia N-terminus Thiolase_N PF00108.18 EWM24705.1 - 5.8e-81 271.3 2.2 5.8e-81 271.3 1.5 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EWM24705.1 - 2.9e-48 162.3 0.6 5.4e-48 161.4 0.4 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 EWM24705.1 - 0.0021 18.0 0.0 0.0066 16.4 0.0 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal AhpC-TSA_2 PF13911.1 EWM24706.1 - 5.2e-19 68.2 0.0 3e-18 65.8 0.0 2.0 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EWM24706.1 - 0.04 13.5 0.0 0.063 12.9 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family HSF_DNA-bind PF00447.12 EWM24707.1 - 8.1e-26 90.2 1.0 1.4e-25 89.4 0.7 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding APG9 PF04109.11 EWM24708.1 - 8.3e-104 347.4 0.0 1e-103 347.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 Myc_N PF01056.13 EWM24708.1 - 0.1 11.7 0.4 0.17 11.0 0.3 1.2 1 0 0 1 1 1 0 Myc amino-terminal region OST3_OST6 PF04756.8 EWM24709.1 - 1.7e-10 40.6 0.5 3.3e-10 39.7 0.4 1.4 1 0 0 1 1 1 1 OST3 / OST6 family DUF4293 PF14126.1 EWM24709.1 - 0.037 13.9 6.3 0.037 13.9 2.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) DUF4131 PF13567.1 EWM24709.1 - 1.2 8.4 11.8 2.8 7.3 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) BT1 PF03092.11 EWM24710.1 - 1.5e-89 300.6 5.6 2.1e-89 300.2 3.9 1.1 1 0 0 1 1 1 1 BT1 family Glyco_tran_WbsX PF14307.1 EWM24711.1 - 0.002 17.3 0.0 0.029 13.5 0.0 2.6 2 1 0 2 2 2 1 Glycosyltransferase WbsX Glyco_hydro_71 PF03659.9 EWM24711.1 - 0.031 12.7 1.0 0.059 11.8 0.7 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 71 zf-C3HC4 PF00097.20 EWM24712.1 - 0.00024 20.6 0.7 0.00024 20.6 0.5 2.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EWM24712.1 - 0.00066 19.4 3.2 0.017 14.9 0.5 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EWM24712.1 - 0.0092 15.9 5.5 0.014 15.4 0.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EWM24712.1 - 0.027 14.3 1.8 0.041 13.7 0.2 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EWM24712.1 - 0.099 12.7 0.1 0.52 10.4 0.0 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_5 PF14634.1 EWM24712.1 - 0.21 11.3 3.8 0.74 9.5 1.1 2.5 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.20 EWM24713.1 - 0.00022 20.7 0.7 0.00022 20.7 0.5 2.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EWM24713.1 - 0.0006 19.5 3.2 0.016 15.0 0.5 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EWM24713.1 - 0.0089 16.0 5.5 0.013 15.5 0.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EWM24713.1 - 0.025 14.4 1.7 0.038 13.8 0.2 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EWM24713.1 - 0.1 12.7 0.1 0.47 10.5 0.0 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_5 PF14634.1 EWM24713.1 - 0.25 11.0 3.8 0.69 9.6 1.1 2.2 2 0 0 2 2 2 0 zinc-RING finger domain ATG_C PF09333.6 EWM24714.1 - 4.1e-28 97.4 0.0 5.3e-27 93.8 0.0 2.2 2 0 0 2 2 2 1 ATG C terminal domain Yippee-Mis18 PF03226.9 EWM24716.1 - 3.5e-19 68.6 1.9 4.6e-19 68.2 1.3 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Chorein_N PF12624.2 EWM24717.1 - 0.00028 20.4 0.0 0.0025 17.3 0.0 1.9 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Pex2_Pex12 PF04757.9 EWM24718.1 - 3.4e-39 134.6 0.7 4.9e-39 134.1 0.5 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 EWM24718.1 - 0.0009 19.2 3.9 0.0015 18.5 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EWM24718.1 - 0.048 13.5 3.3 0.083 12.7 2.3 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.1 EWM24718.1 - 0.29 10.8 2.5 0.47 10.1 1.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EWM24718.1 - 0.69 9.8 2.8 1.3 9.0 2.0 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Tubulin PF00091.20 EWM24719.1 - 1.6e-73 247.1 0.0 2.4e-73 246.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EWM24719.1 - 3.4e-45 153.1 0.5 6.6e-45 152.2 0.3 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EWM24719.1 - 5.5e-06 26.4 0.0 1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EWM24719.1 - 0.05 13.0 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain TctB PF07331.6 EWM24720.1 - 2.4 7.8 8.7 0.049 13.2 1.3 1.6 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family ThiF PF00899.16 EWM24721.1 - 4.6e-39 133.3 0.0 9.1e-39 132.4 0.0 1.5 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 EWM24721.1 - 3.4e-21 74.5 0.1 5.6e-21 73.8 0.0 1.3 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein E2_bind PF08825.5 EWM24721.1 - 6.3e-19 67.5 0.4 1e-18 66.8 0.3 1.3 1 0 0 1 1 1 1 E2 binding domain UBA_e1_thiolCys PF10585.4 EWM24721.1 - 6.6e-12 44.6 1.5 1.1e-11 43.9 1.0 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site MoeZ_MoeB PF05237.8 EWM24721.1 - 0.00032 20.2 1.2 0.00055 19.4 0.0 2.0 2 0 0 2 2 2 1 MoeZ/MoeB domain Shikimate_DH PF01488.15 EWM24721.1 - 0.00032 20.7 0.0 0.00061 19.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase UAE_UbL PF14732.1 EWM24721.1 - 0.0012 18.9 0.0 0.0035 17.4 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_C PF09358.5 EWM24721.1 - 0.063 13.4 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-activating enzyme e1 C-terminal domain Lipase_3 PF01764.20 EWM24723.1 - 2.6e-23 82.2 0.0 6.9e-23 80.8 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) Myb_DNA-binding PF00249.26 EWM24723.1 - 1.7e-21 75.9 2.3 1.8e-10 40.7 0.2 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EWM24723.1 - 8e-20 70.7 2.9 3e-15 56.0 0.1 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain MIG-14_Wnt-bd PF06664.7 EWM24723.1 - 2.9e-06 26.3 5.2 1.4e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion DUF2974 PF11187.3 EWM24723.1 - 0.027 13.8 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) zf-LYAR PF08790.6 EWM24724.1 - 6.1e-16 57.8 3.7 4e-15 55.2 1.0 2.3 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf-TRAF PF02176.13 EWM24724.1 - 0.0013 19.0 1.1 0.0062 16.8 0.8 2.0 2 0 0 2 2 2 1 TRAF-type zinc finger Inhibitor_I29 PF08246.7 EWM24724.1 - 0.08 13.2 0.9 0.21 11.8 0.6 1.7 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) DUF2992 PF11208.3 EWM24724.1 - 0.17 11.8 10.3 0.25 11.2 6.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2992) DUF2956 PF11169.3 EWM24724.1 - 0.18 11.7 8.2 0.44 10.5 5.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Gon7 PF08738.5 EWM24724.1 - 0.39 10.7 5.9 0.35 10.8 0.1 2.4 1 1 1 2 2 2 0 Gon7 family zf-C2H2 PF00096.21 EWM24724.1 - 3.7 8.0 7.9 8.7 6.9 0.2 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type ATP_synt_I PF03899.10 EWM24725.1 - 0.00022 21.3 8.4 0.00039 20.5 5.9 1.5 1 0 0 1 1 1 1 ATP synthase I chain G-patch PF01585.18 EWM24726.1 - 3.2e-08 33.2 6.5 1.4e-07 31.2 4.5 2.2 1 0 0 1 1 1 1 G-patch domain Cpn60_TCP1 PF00118.19 EWM24729.1 - 1.1e-155 518.9 0.0 1.3e-155 518.7 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Asn_synthase PF00733.16 EWM24730.1 - 1.4e-20 73.9 0.0 1.1e-19 70.9 0.0 2.0 1 1 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.12 EWM24730.1 - 0.0045 15.9 0.0 0.0063 15.4 0.0 1.2 1 0 0 1 1 1 1 NAD synthase ATP_bind_4 PF01902.12 EWM24730.1 - 0.022 14.1 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 ATP-binding region QueC PF06508.8 EWM24730.1 - 0.066 12.4 0.0 0.25 10.6 0.0 1.9 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC DZR PF12773.2 EWM24730.1 - 0.067 13.0 0.5 0.15 11.9 0.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon tRNA_Me_trans PF03054.11 EWM24730.1 - 0.11 11.0 0.0 0.15 10.5 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase PAPS_reduct PF01507.14 EWM24730.1 - 0.16 11.7 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Ank_2 PF12796.2 EWM24731.1 - 1.4e-15 57.3 2.4 3.8e-06 27.1 0.0 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EWM24731.1 - 2.6e-12 46.5 0.2 8.8e-07 28.9 0.0 5.0 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.25 EWM24731.1 - 6.8e-09 35.1 0.4 2.3 8.1 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 EWM24731.1 - 5.7e-07 29.1 0.0 3.8 8.0 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 EWM24731.1 - 4.1e-06 27.1 0.0 0.13 12.8 0.0 4.4 3 1 3 6 6 6 2 Ankyrin repeats (many copies) DUF503 PF04456.7 EWM24731.1 - 0.043 13.4 0.0 0.13 11.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF503) Laminin_II PF06009.7 EWM24731.1 - 0.05 13.3 0.1 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 Laminin Domain II Trypan_PARP PF05887.6 EWM24732.1 - 0.71 9.6 7.7 0.87 9.3 5.3 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Dishevelled PF02377.10 EWM24733.1 - 9.5 6.5 12.2 0.3 11.3 1.4 3.3 2 1 1 3 3 3 0 Dishevelled specific domain START PF01852.14 EWM24734.1 - 4.9e-06 26.0 0.0 8.1e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 START domain DUF4527 PF15030.1 EWM24734.1 - 0.098 11.9 4.7 0.13 11.5 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) Cortex-I_coil PF09304.5 EWM24734.1 - 0.81 9.7 10.7 5.1 7.1 7.4 1.8 1 1 0 1 1 1 0 Cortexillin I, coiled coil PI3_PI4_kinase PF00454.22 EWM24735.1 - 7e-23 81.3 0.0 9.6e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase ubiquitin PF00240.18 EWM24735.1 - 2.8e-08 33.0 0.0 8.4e-08 31.5 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 EWM24735.1 - 0.071 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like PI3_PI4_kinase PF00454.22 EWM24736.1 - 2e-23 83.0 0.0 2.4e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PALP PF00291.20 EWM24737.1 - 1.9e-60 204.7 0.7 2.6e-60 204.2 0.5 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Asp_Arg_Hydrox PF05118.10 EWM24738.1 - 5.1e-25 88.2 0.0 7.1e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Cupin_2 PF07883.6 EWM24738.1 - 0.012 15.0 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Cupin domain Lin0512_fam PF09585.5 EWM24740.1 - 2.2e-38 130.3 0.1 3.3e-38 129.7 0.1 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein (Lin0512_fam) NAC PF01849.13 EWM24741.1 - 5.4e-22 77.0 0.2 1.6e-21 75.5 0.1 1.8 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 EWM24741.1 - 0.026 14.3 0.4 0.044 13.6 0.3 1.4 1 0 0 1 1 1 0 UBA/TS-N domain CDC45 PF02724.9 EWM24741.1 - 0.12 10.4 3.9 0.14 10.1 2.7 1.1 1 0 0 1 1 1 0 CDC45-like protein PRP21_like_P PF12230.3 EWM24741.1 - 0.14 11.6 5.0 0.19 11.2 3.4 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein Daxx PF03344.10 EWM24741.1 - 0.21 10.0 6.2 0.26 9.7 4.3 1.1 1 0 0 1 1 1 0 Daxx Family Myc_N PF01056.13 EWM24741.1 - 0.44 9.6 4.8 0.68 9.0 3.3 1.4 1 0 0 1 1 1 0 Myc amino-terminal region DUF2890 PF11081.3 EWM24741.1 - 1.2 9.1 8.9 2.5 8.1 6.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) HSP90 PF00183.13 EWM24741.1 - 2.7 6.3 7.2 3.3 6.0 5.0 1.2 1 0 0 1 1 1 0 Hsp90 protein TFIIF_alpha PF05793.7 EWM24741.1 - 4.5 5.5 16.1 6 5.1 11.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PBP_sp32 PF07222.7 EWM24741.1 - 5.8 6.0 12.6 9 5.3 8.8 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DIOX_N PF14226.1 EWM24743.1 - 1.7e-06 28.5 0.0 2.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Peptidase_C54 PF03416.14 EWM24744.1 - 5e-21 75.0 0.0 7.5e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 DUF740 PF05340.7 EWM24744.1 - 0.56 8.4 1.8 0.73 8.1 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Peptidase_C54 PF03416.14 EWM24746.1 - 4e-15 55.7 0.1 5e-15 55.3 0.1 1.1 1 0 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.8 EWM24746.1 - 0.062 12.4 0.1 0.087 11.9 0.1 1.1 1 0 0 1 1 1 0 Peptidase family C78 MFS_1 PF07690.11 EWM24747.1 - 6.3e-13 48.1 13.2 1.2e-12 47.2 9.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EWM24747.1 - 0.0056 15.3 3.5 0.016 13.8 2.4 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter 5-FTHF_cyc-lig PF01812.15 EWM24754.1 - 3e-10 40.1 0.1 4e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Adipokin_hormo PF06377.6 EWM24754.1 - 0.12 12.5 0.3 0.29 11.2 0.2 1.6 1 0 0 1 1 1 0 Adipokinetic hormone RRM_1 PF00076.17 EWM24755.1 - 0.0002 20.9 0.0 0.00032 20.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AMMECR1 PF01871.12 EWM24756.1 - 6.2e-40 136.1 0.0 7.6e-40 135.8 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 DUF508 PF04370.7 EWM24756.1 - 5.4 6.6 6.2 9 5.8 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF508) gag_pre-integrs PF13976.1 EWM24758.1 - 1.9e-06 27.3 0.0 3.6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain MRI PF15325.1 EWM24758.1 - 5.3 8.0 12.2 0.12 13.2 2.7 2.3 1 1 2 3 3 3 0 Modulator of retrovirus infection Arrestin_N PF00339.24 EWM24759.1 - 2.1e-12 47.0 0.0 6.4e-12 45.5 0.0 1.6 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EWM24759.1 - 0.00057 19.9 0.0 0.0026 17.8 0.0 1.9 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Spo0M PF07070.6 EWM24759.1 - 0.0098 15.2 0.0 0.024 13.9 0.0 1.7 1 1 0 1 1 1 1 SpoOM protein Exo_endo_phos PF03372.18 EWM24760.1 - 2.3e-10 40.8 0.5 3e-10 40.4 0.3 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EWM24760.1 - 0.0094 15.5 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase AP2 PF00847.15 EWM24761.1 - 0.16 12.1 0.1 0.35 11.0 0.1 1.5 1 0 0 1 1 1 0 AP2 domain RRM_1 PF00076.17 EWM24762.1 - 2.5e-20 71.8 0.0 3.6e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM24762.1 - 9.3e-13 47.9 0.0 1.4e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM24762.1 - 4.6e-10 39.1 0.0 7.2e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cid2 PF09774.4 EWM24762.1 - 0.0076 16.3 0.0 0.0093 16.0 0.0 1.2 1 0 0 1 1 1 1 Caffeine-induced death protein 2 OB_RNB PF08206.6 EWM24762.1 - 0.11 11.9 0.8 0.24 10.9 0.0 1.9 2 0 0 2 2 2 0 Ribonuclease B OB domain AP2 PF00847.15 EWM24765.1 - 1.2e-08 35.0 1.4 1.7e-08 34.5 1.0 1.3 1 0 0 1 1 1 1 AP2 domain DUF4278 PF14105.1 EWM24765.1 - 0.12 12.3 0.4 0.47 10.4 0.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4278) PEHE PF15275.1 EWM24767.1 - 0.49 10.8 5.0 0.54 10.7 2.7 1.6 1 1 0 1 1 1 0 PEHE domain Caldesmon PF02029.10 EWM24767.1 - 8.2 4.7 6.2 12 4.2 4.3 1.1 1 0 0 1 1 1 0 Caldesmon ADIP PF11559.3 EWM24768.1 - 0.6 10.0 5.1 1.2 9.0 3.5 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding UQ_con PF00179.21 EWM24769.1 - 2.4e-18 65.9 0.0 3.9e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EWM24769.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 RWD domain tRNA_int_endo PF01974.12 EWM24772.1 - 2.2e-14 53.0 0.0 3.6e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain DNA_processg_A PF02481.10 EWM24772.1 - 0.035 12.9 0.0 0.059 12.2 0.0 1.2 1 0 0 1 1 1 0 DNA recombination-mediator protein A TFIIS_M PF07500.9 EWM24773.1 - 0.0077 16.2 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain Acyl_transf_3 PF01757.17 EWM24774.1 - 5.5e-14 51.7 28.7 8.8e-14 51.0 19.9 1.2 1 0 0 1 1 1 1 Acyltransferase family Totivirus_coat PF05518.6 EWM24777.1 - 1.9 6.1 4.7 2.9 5.5 3.3 1.2 1 0 0 1 1 1 0 Totivirus coat protein Thioredoxin_8 PF13905.1 EWM24778.1 - 8.7e-10 38.5 0.0 1.2e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EWM24778.1 - 0.0022 17.6 0.0 0.0029 17.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.1 EWM24778.1 - 0.0029 17.8 0.0 0.0042 17.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Nop25 PF09805.4 EWM24780.1 - 1.2e-16 61.0 3.5 1.2e-16 61.0 2.4 2.0 1 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) DUF3086 PF11285.3 EWM24780.1 - 0.028 13.2 0.1 0.039 12.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) DUF1115 PF06544.7 EWM24781.1 - 1.3e-24 86.3 0.3 2.7e-24 85.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) PRP3 PF08572.5 EWM24781.1 - 6.3e-17 61.7 0.5 6.3e-17 61.7 0.4 1.8 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) TOM_sub5 PF15178.1 EWM24781.1 - 0.024 14.3 0.4 0.057 13.1 0.3 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM5 homolog Spt5_N PF11942.3 EWM24781.1 - 0.034 14.7 1.1 0.034 14.7 0.7 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Cut12 PF11500.3 EWM24781.1 - 0.65 9.6 5.5 0.16 11.6 1.5 1.7 2 0 0 2 2 2 0 Spindle pole body formation-associated protein GTP_EFTU PF00009.22 EWM24782.1 - 0.00067 19.1 0.0 0.0007 19.0 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF218 PF02698.12 EWM24782.1 - 0.058 12.8 0.0 0.066 12.7 0.0 1.1 1 0 0 1 1 1 0 DUF218 domain ArgK PF03308.11 EWM24782.1 - 0.13 11.0 0.0 0.15 10.8 0.0 1.0 1 0 0 1 1 1 0 ArgK protein WD40 PF00400.27 EWM24783.1 - 3.9e-24 83.5 0.1 1.6e-10 40.4 0.1 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat eIF2A PF08662.6 EWM24783.1 - 0.0078 15.9 0.0 0.011 15.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Skp1 PF01466.14 EWM24786.1 - 7.4e-07 29.1 0.1 1.2e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain BTB PF00651.26 EWM24786.1 - 0.084 12.8 0.0 0.92 9.5 0.0 2.2 1 1 1 2 2 2 0 BTB/POZ domain Pro_3_hydrox_C PF05373.6 EWM24786.1 - 0.091 12.8 0.0 5.5 7.0 0.0 2.2 2 0 0 2 2 2 0 L-proline 3-hydroxylase, C-terminal Lipoprotein_20 PF13942.1 EWM24790.1 - 0.00041 19.9 0.2 0.00041 19.9 0.2 2.2 2 0 0 2 2 2 1 YfhG lipoprotein Uds1 PF15456.1 EWM24790.1 - 0.0024 17.8 10.5 0.0056 16.6 7.3 1.7 1 0 0 1 1 1 1 Up-regulated During Septation Macoilin PF09726.4 EWM24790.1 - 0.019 13.2 8.8 0.035 12.3 6.1 1.4 1 0 0 1 1 1 0 Transmembrane protein Spectrin PF00435.16 EWM24790.1 - 0.32 11.2 12.6 1.9 8.8 1.0 2.8 2 1 1 3 3 3 0 Spectrin repeat DUF724 PF05266.9 EWM24790.1 - 0.8 9.2 10.5 0.39 10.3 5.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) APG6 PF04111.7 EWM24790.1 - 0.9 8.5 8.3 1.6 7.6 5.7 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 NPV_P10 PF05531.7 EWM24790.1 - 0.93 9.7 2.7 7.2 6.9 0.6 3.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Med9 PF07544.8 EWM24790.1 - 1.5 8.5 8.0 6.8 6.4 0.1 2.9 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF4407 PF14362.1 EWM24790.1 - 1.8 7.4 14.0 0.35 9.7 6.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HrpA_pilin PF09589.5 EWM24790.1 - 2.3 8.6 5.5 40 4.6 3.8 2.9 1 1 0 1 1 1 0 HrpA pilus formation protein DUF607 PF04678.8 EWM24790.1 - 2.4 8.0 8.1 25 4.7 5.6 2.3 1 1 0 1 1 1 0 Protein of unknown function, DUF607 Tropomyosin_1 PF12718.2 EWM24790.1 - 4.2 7.2 18.3 3.9 7.3 11.0 2.2 2 1 0 2 2 2 0 Tropomyosin like DUF3276 PF11680.3 EWM24791.1 - 0.094 12.5 4.2 0.24 11.1 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3276) Rabaptin PF03528.10 EWM24791.1 - 0.28 11.1 23.0 0.024 14.5 4.6 3.0 2 1 1 3 3 3 0 Rabaptin AAA_13 PF13166.1 EWM24791.1 - 2.7 6.3 9.9 4.2 5.7 6.9 1.3 1 1 0 1 1 1 0 AAA domain TMCO5 PF14992.1 EWM24791.1 - 3.6 6.6 10.2 7.5 5.5 7.0 1.5 1 1 0 1 1 1 0 TMCO5 family SR-25 PF10500.4 EWM24795.1 - 0.56 9.6 6.9 0.68 9.3 4.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Homeobox_KN PF05920.6 EWM24796.1 - 1.7e-07 30.8 0.4 2.8e-07 30.1 0.3 1.3 1 0 0 1 1 1 1 Homeobox KN domain DUF3628 PF12300.3 EWM24796.1 - 0.64 10.0 8.6 1.4 8.9 6.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3628) PT PF04886.7 EWM24799.1 - 1.5e-13 49.7 46.7 0.23 10.8 32.4 2.7 1 1 0 1 1 1 1 PT repeat BNR PF02012.15 EWM24799.1 - 0.87 9.6 4.7 0.57 10.2 1.0 2.6 3 0 0 3 3 3 0 BNR/Asp-box repeat TFIIA PF03153.8 EWM24799.1 - 1.2 8.9 3.6 1.4 8.7 2.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 EWM24799.1 - 6.1 4.9 9.0 7.5 4.6 6.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Methyltransf_23 PF13489.1 EWM24800.1 - 1e-06 28.5 0.0 2e-06 27.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM24800.1 - 9.8e-06 25.9 0.0 0.047 14.1 0.0 2.5 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_25 PF13649.1 EWM24800.1 - 0.00011 22.4 0.0 0.025 14.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM24800.1 - 0.00069 20.0 0.0 0.82 10.1 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EWM24800.1 - 0.00089 19.8 0.0 0.0047 17.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EWM24800.1 - 0.037 12.9 0.0 0.12 11.3 0.0 1.7 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family UBN2_2 PF14227.1 EWM24802.1 - 3.2e-07 29.9 0.6 4.6e-07 29.4 0.4 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EWM24802.1 - 5.1e-06 26.2 0.2 8.7e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF1759 PF03564.10 EWM24802.1 - 0.00012 21.9 0.5 0.00059 19.6 0.1 2.1 2 1 1 3 3 3 1 Protein of unknown function (DUF1759) PP-binding PF00550.20 EWM24802.1 - 0.11 12.8 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Phosphopantetheine attachment site zf-CCHC_4 PF14392.1 EWM24802.1 - 0.33 10.6 2.1 0.48 10.1 0.4 2.0 2 0 0 2 2 2 0 Zinc knuckle DUF1759 PF03564.10 EWM24811.1 - 0.0072 16.1 0.3 0.098 12.4 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1759) RVT_2 PF07727.9 EWM24812.1 - 1.6e-12 46.9 0.1 4.1e-12 45.5 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) CbiG_N PF11760.3 EWM24814.1 - 0.03 14.0 0.2 3.1 7.5 0.0 2.9 3 1 1 4 4 4 0 Cobalamin synthesis G N-terminal rve PF00665.21 EWM24815.1 - 2.8e-11 43.5 0.0 4.5e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain RVT_2 PF07727.9 EWM24818.1 - 2e-41 141.6 0.0 2.6e-40 137.9 0.0 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 EWM24819.1 - 5.7e-69 231.8 0.0 7.2e-69 231.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RXT2_N PF08595.6 EWM24820.1 - 0.022 14.5 1.8 0.046 13.5 1.3 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF21 PF01595.15 EWM24822.1 - 4.7e-14 52.1 0.2 6.6e-14 51.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 DUF21 PF01595.15 EWM24823.1 - 6.7e-14 51.5 0.2 9.8e-14 51.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 TH1 PF04858.8 EWM24825.1 - 0.19 9.8 0.0 0.26 9.3 0.0 1.1 1 0 0 1 1 1 0 TH1 protein HSP70 PF00012.15 EWM24828.1 - 3.9e-27 94.4 0.0 3.9e-26 91.1 0.0 1.9 1 1 0 1 1 1 1 Hsp70 protein Herpes_gE PF02480.11 EWM24830.1 - 3.2 5.9 0.0 3.2 5.9 0.0 3.6 4 1 0 4 4 4 0 Alphaherpesvirus glycoprotein E Arf PF00025.16 EWM24831.1 - 1.2e-67 226.5 0.0 1.4e-67 226.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EWM24831.1 - 8.1e-13 48.0 0.0 1e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EWM24831.1 - 5.2e-10 38.5 0.2 2.8e-07 29.5 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EWM24831.1 - 2.3e-09 36.7 0.0 2.8e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EWM24831.1 - 2.3e-09 36.7 0.0 2.9e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EWM24831.1 - 6.4e-09 36.3 0.0 1e-08 35.6 0.0 1.4 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EWM24831.1 - 7.5e-05 22.6 0.0 0.0001 22.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EWM24831.1 - 0.071 12.5 0.0 0.42 10.0 0.0 1.8 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Arf PF00025.16 EWM24832.1 - 1.2e-56 190.6 0.0 1.5e-56 190.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EWM24832.1 - 6.3e-13 48.4 0.0 8e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EWM24832.1 - 4e-10 38.9 0.3 2.3e-07 29.8 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EWM24832.1 - 1.7e-09 37.1 0.0 2.1e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EWM24832.1 - 1.8e-09 37.0 0.0 2.2e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EWM24832.1 - 5.2e-09 36.6 0.0 7.9e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EWM24832.1 - 5.8e-05 23.0 0.0 7.8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EWM24832.1 - 0.14 11.5 0.0 0.95 8.8 0.0 1.8 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain DUF561 PF04481.7 EWM24833.1 - 6.1e-74 248.0 0.0 7.8e-74 247.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF561) Arf PF00025.16 EWM24834.1 - 1.5e-67 226.1 0.0 1.9e-67 225.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EWM24834.1 - 9.1e-15 54.4 0.0 1.1e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EWM24834.1 - 2.6e-12 46.3 0.0 3.3e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EWM24834.1 - 1.1e-10 41.0 0.0 1.4e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EWM24834.1 - 1.3e-10 41.8 0.0 1.6e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 EWM24834.1 - 1.3e-10 40.5 2.2 4.9e-08 32.0 0.4 2.2 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 EWM24834.1 - 3e-05 23.9 0.0 4.3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EWM24834.1 - 0.0048 16.3 0.0 0.03 13.7 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EWM24834.1 - 0.029 14.5 0.2 0.16 12.1 0.2 1.9 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EWM24834.1 - 0.043 13.4 0.1 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 NACHT domain 6PF2K PF01591.13 EWM24834.1 - 0.13 11.3 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_16 PF13191.1 EWM24834.1 - 0.24 11.3 2.2 5.3 6.9 0.3 2.1 1 1 0 2 2 2 0 AAA ATPase domain PAP2 PF01569.16 EWM24835.1 - 0.0011 18.6 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 PAP2 superfamily DUF4500 PF14937.1 EWM24836.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) SNURF PF07192.6 EWM24837.1 - 0.12 12.2 1.9 0.28 11.0 1.3 1.6 1 0 0 1 1 1 0 SNURF/RPN4 protein DUF2960 PF11173.3 EWM24838.1 - 0.0055 16.9 0.5 0.018 15.3 0.1 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF2960) UQ_con PF00179.21 EWM24840.1 - 2.9e-46 156.3 0.0 3.5e-46 156.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EWM24840.1 - 5e-05 23.0 0.0 6.2e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EWM24840.1 - 0.0026 17.6 0.0 0.0026 17.6 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EWM24840.1 - 0.049 13.3 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain LCM PF04072.9 EWM24841.1 - 3.2e-07 30.0 1.1 4.3e-06 26.4 0.8 2.2 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase CD36 PF01130.16 EWM24842.1 - 1.9e-25 89.1 0.0 2.5e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 CD36 family CD36 PF01130.16 EWM24843.1 - 6.3e-13 47.8 0.0 7.8e-12 44.2 0.0 2.1 1 1 0 1 1 1 1 CD36 family NolV PF06635.7 EWM24844.1 - 0.57 9.3 3.3 0.41 9.7 0.6 1.8 2 0 0 2 2 2 0 Nodulation protein NolV OmpH PF03938.9 EWM24844.1 - 1.1 9.1 11.1 1.7 8.5 7.7 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SRR1 PF07985.7 EWM24845.1 - 1.3e-10 41.0 0.6 9.6e-06 25.4 0.0 2.4 2 0 0 2 2 2 2 SRR1 Zn_clus PF00172.13 EWM24849.1 - 0.00041 20.1 14.8 0.00075 19.3 10.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Chon_Sulph_att PF06566.6 EWM24851.1 - 0.0018 17.9 0.1 0.0028 17.3 0.1 1.3 1 0 0 1 1 1 1 Chondroitin sulphate attachment domain Chon_Sulph_att PF06566.6 EWM24852.1 - 0.0018 17.9 0.1 0.0028 17.3 0.1 1.3 1 0 0 1 1 1 1 Chondroitin sulphate attachment domain Myc_N PF01056.13 EWM24853.1 - 0.016 14.3 3.0 0.024 13.8 2.1 1.3 1 0 0 1 1 1 0 Myc amino-terminal region BSP_II PF05432.6 EWM24853.1 - 0.027 13.7 6.0 0.035 13.4 4.2 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) FHIPEP PF00771.15 EWM24853.1 - 0.065 11.5 0.0 0.075 11.3 0.0 1.0 1 0 0 1 1 1 0 FHIPEP family Sigma70_ner PF04546.8 EWM24853.1 - 0.073 12.6 1.5 0.098 12.2 1.0 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 EWM24853.1 - 1.2 8.6 5.9 1.8 8.0 4.1 1.2 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 EWM24853.1 - 1.8 8.8 7.5 2.8 8.2 5.2 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SAP PF02037.22 EWM24856.1 - 0.0012 18.2 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 SAP domain Rho_N PF07498.7 EWM24856.1 - 0.0016 18.1 0.0 0.0022 17.7 0.0 1.1 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain LETM1 PF07766.8 EWM24856.1 - 0.024 13.6 0.2 0.036 13.0 0.1 1.2 1 0 0 1 1 1 0 LETM1-like protein TniQ PF06527.6 EWM24857.1 - 0.062 13.5 0.3 0.062 13.5 0.2 1.1 1 0 0 1 1 1 0 TniQ Snf7 PF03357.16 EWM24858.1 - 2.2e-43 147.6 6.3 2.7e-43 147.3 4.3 1.0 1 0 0 1 1 1 1 Snf7 Prefoldin_2 PF01920.15 EWM24858.1 - 0.00025 20.7 1.4 3.6 7.3 0.2 3.3 2 1 0 3 3 3 2 Prefoldin subunit NgoMIV_restric PF09015.5 EWM24858.1 - 0.018 14.0 0.5 0.023 13.7 0.3 1.1 1 0 0 1 1 1 0 NgoMIV restriction enzyme PLU-1 PF08429.6 EWM24858.1 - 0.033 13.1 0.5 0.041 12.7 0.3 1.0 1 0 0 1 1 1 0 PLU-1-like protein NPV_P10 PF05531.7 EWM24858.1 - 0.055 13.7 8.4 0.48 10.7 1.7 3.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.1 EWM24858.1 - 0.058 11.8 3.1 0.16 10.3 2.2 1.6 1 1 0 1 1 1 0 AAA domain DUF848 PF05852.6 EWM24858.1 - 0.2 11.4 3.3 0.21 11.4 1.3 1.8 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DASH_Dam1 PF08653.5 EWM24858.1 - 0.28 10.9 2.2 6.8 6.5 0.2 2.8 3 0 0 3 3 3 0 DASH complex subunit Dam1 DUF2051 PF09738.4 EWM24858.1 - 0.33 10.1 0.1 0.33 10.1 0.1 2.1 1 1 1 2 2 2 0 Double stranded RNA binding protein (DUF2051) Seryl_tRNA_N PF02403.17 EWM24858.1 - 0.39 10.7 9.7 10 6.2 3.5 2.8 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Flagellin_N PF00669.15 EWM24858.1 - 0.88 9.3 5.5 7.7 6.3 2.8 2.6 1 1 2 3 3 3 0 Bacterial flagellin N-terminal helical region Rad60-SLD PF11976.3 EWM24860.1 - 9.7e-14 50.8 0.0 8.7e-10 38.1 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EWM24860.1 - 1.1e-05 24.7 0.0 0.00027 20.2 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin family Globin PF00042.17 EWM24861.1 - 2.3e-10 40.7 0.0 7.7e-10 39.0 0.0 1.8 2 0 0 2 2 2 1 Globin FAD_binding_6 PF00970.19 EWM24861.1 - 2.4e-08 33.9 0.0 0.0015 18.6 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase FAD-binding domain Lactamase_B_2 PF12706.2 EWM24862.1 - 6e-12 45.5 0.0 2.9e-11 43.2 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Ribosomal_L50 PF10501.4 EWM24862.1 - 0.093 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal subunit 39S DUF1446 PF07287.6 EWM24862.1 - 0.11 10.9 0.1 0.16 10.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1446) Lactamase_B_2 PF12706.2 EWM24863.1 - 3.4e-10 39.7 0.0 5.7e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Ribosomal_L50 PF10501.4 EWM24863.1 - 0.077 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal subunit 39S DUF1446 PF07287.6 EWM24863.1 - 0.085 11.3 0.1 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1446) Lactococcin_972 PF09683.5 EWM24864.1 - 0.93 9.8 10.4 4.1 7.8 0.4 2.1 2 0 0 2 2 2 0 Bacteriocin (Lactococcin_972) HOOK PF05622.7 EWM24867.1 - 0.027 12.3 2.0 0.029 12.1 1.4 1.2 1 0 0 1 1 1 0 HOOK protein BRE1 PF08647.6 EWM24867.1 - 0.034 14.1 3.7 0.04 13.8 2.6 1.1 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase GOLGA2L5 PF15070.1 EWM24867.1 - 0.037 12.5 2.1 0.045 12.2 1.5 1.2 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 DUF2496 PF10689.4 EWM24867.1 - 0.062 12.8 0.3 0.15 11.7 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2496) Surfac_D-trimer PF09006.6 EWM24867.1 - 0.072 12.8 0.7 6 6.6 0.0 2.4 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Nup54 PF13874.1 EWM24867.1 - 0.1 12.2 1.2 0.13 11.9 0.8 1.1 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Reo_sigmaC PF04582.7 EWM24867.1 - 0.1 11.7 0.1 0.12 11.5 0.1 1.0 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Sec2p PF06428.6 EWM24867.1 - 0.17 11.7 7.2 0.35 10.7 5.0 1.6 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF3450 PF11932.3 EWM24867.1 - 0.2 10.8 2.7 0.099 11.8 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF812 PF05667.6 EWM24867.1 - 0.21 10.0 2.5 0.25 9.7 1.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Cep57_CLD_2 PF14197.1 EWM24867.1 - 0.22 11.4 3.7 0.59 10.1 0.1 2.6 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Spectrin PF00435.16 EWM24867.1 - 0.29 11.4 3.4 0.79 10.0 2.3 1.7 1 1 0 1 1 1 0 Spectrin repeat CENP-F_leu_zip PF10473.4 EWM24867.1 - 0.37 10.6 6.4 0.43 10.4 0.4 2.1 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mu-like_Pro PF10123.4 EWM24867.1 - 0.61 9.4 4.4 0.67 9.3 3.1 1.0 1 0 0 1 1 1 0 Mu-like prophage I protein Sbi-IV PF11621.3 EWM24867.1 - 0.67 10.1 4.5 0.72 10.0 1.4 2.2 2 1 1 3 3 3 0 C3 binding domain 4 of IgG-bind protein SBI DUF4140 PF13600.1 EWM24867.1 - 1.1 9.6 6.8 1.6 9.1 1.8 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) TPR_MLP1_2 PF07926.7 EWM24867.1 - 1.4 8.6 8.0 3 7.6 5.6 1.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein bZIP_2 PF07716.10 EWM24867.1 - 2.4 8.0 6.4 11 5.9 0.4 2.4 2 1 0 2 2 2 0 Basic region leucine zipper DivIC PF04977.10 EWM24867.1 - 9.9 5.7 7.3 3.9 7.0 1.1 2.5 1 1 0 2 2 2 0 Septum formation initiator Nop53 PF07767.6 EWM24868.1 - 6.3e-32 111.0 27.1 1.2e-31 110.0 18.8 1.4 1 1 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Peptidase_M16_C PF05193.16 EWM24872.1 - 6.4e-07 29.2 0.0 1.1e-06 28.4 0.0 1.4 1 1 1 2 2 2 1 Peptidase M16 inactive domain APC_crr PF05923.7 EWM24873.1 - 0.4 10.3 2.3 1.1 9.0 1.6 1.7 1 0 0 1 1 1 0 APC cysteine-rich region Peptidase_M16 PF00675.15 EWM24874.1 - 2.2e-41 141.0 0.0 2.6e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Methyltransf_21 PF05050.7 EWM24875.1 - 1e-12 48.3 0.0 1.4e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_18 PF12847.2 EWM24875.1 - 0.00097 19.6 0.1 0.0019 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM24875.1 - 0.031 14.0 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Nsp1_C PF05064.8 EWM24880.1 - 0.015 14.9 0.0 0.029 13.9 0.0 1.5 1 1 0 1 1 1 0 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 EWM24880.1 - 5.4 7.2 106.9 2.6 8.2 19.7 3.9 1 1 3 4 4 4 0 Nucleoporin FG repeat region DUF393 PF04134.7 EWM24881.1 - 3.8e-20 73.1 0.0 6.8e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF393 adh_short_C2 PF13561.1 EWM24882.1 - 3.8e-34 118.5 0.0 4.6e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EWM24882.1 - 3.6e-27 95.3 0.2 4.5e-27 95.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EWM24882.1 - 5.8e-10 39.1 0.1 8.3e-10 38.6 0.1 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EWM24882.1 - 0.011 14.6 0.1 0.015 14.2 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EWM24882.1 - 0.014 15.1 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 EWM24882.1 - 0.018 14.2 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EWM24882.1 - 0.06 12.7 0.1 0.09 12.1 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF2737 PF10930.3 EWM24883.1 - 0.037 13.6 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2737) E1-E2_ATPase PF00122.15 EWM24884.1 - 9.1e-41 139.3 3.6 1.5e-37 128.8 0.0 3.4 3 0 0 3 3 3 3 E1-E2 ATPase Hydrolase PF00702.21 EWM24884.1 - 1.9e-17 64.3 1.7 7.5e-16 59.1 1.2 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EWM24884.1 - 2.2e-05 24.7 0.1 6.5e-05 23.1 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EWM24884.1 - 0.074 13.2 0.3 0.17 12.0 0.2 1.6 1 0 0 1 1 1 0 Heavy-metal-associated domain TALPID3 PF15324.1 EWM24885.1 - 0.26 8.6 3.9 0.33 8.2 2.7 1.1 1 0 0 1 1 1 0 Hedgehog signalling target Phosphoprotein PF00922.12 EWM24885.1 - 0.28 10.3 2.5 0.48 9.6 1.7 1.4 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein Pkinase PF00069.20 EWM24886.1 - 1.6e-60 204.4 0.0 1.8e-59 201.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM24886.1 - 5.4e-31 107.6 0.0 2.5e-30 105.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EWM24886.1 - 5.6e-05 22.2 0.0 9e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DLH PF01738.13 EWM24886.1 - 0.027 13.7 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family SPO11_like PF03533.9 EWM24886.1 - 0.077 12.8 3.4 0.3 10.9 0.6 2.8 2 0 0 2 2 2 0 SPO11 homologue YrbL-PhoP_reg PF10707.4 EWM24886.1 - 0.13 11.5 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL UPRTase PF14681.1 EWM24887.1 - 3e-67 225.8 0.0 3.9e-67 225.4 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EWM24887.1 - 0.0018 17.9 0.0 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DOT1 PF08123.8 EWM24888.1 - 6.4e-11 41.9 0.0 1.2e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 EWM24888.1 - 0.00011 22.7 0.0 0.00092 19.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM24888.1 - 0.0014 18.6 0.1 0.0036 17.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 EWM24888.1 - 0.0072 15.8 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 EWM24888.1 - 0.021 13.8 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_31 PF13847.1 EWM24888.1 - 0.085 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PITH PF06201.8 EWM24889.1 - 1.9e-36 125.1 0.1 2.2e-36 124.9 0.0 1.0 1 0 0 1 1 1 1 PITH domain Sad1_UNC PF07738.8 EWM24889.1 - 0.063 13.0 0.0 0.094 12.5 0.0 1.3 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal PDH PF02153.12 EWM24890.1 - 0.05 12.4 0.0 1.9 7.3 0.1 2.2 2 0 0 2 2 2 0 Prephenate dehydrogenase Shal-type PF11601.3 EWM24891.1 - 0.11 12.0 0.1 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Shal-type voltage-gated potassium channels Solute_trans_a PF03619.11 EWM24892.1 - 1.7e-19 70.2 0.0 2.1e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Lung_7-TM_R PF06814.8 EWM24893.1 - 3.4e-55 187.0 8.9 4.6e-55 186.6 6.2 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.4 EWM24893.1 - 3.4e-09 36.2 7.4 6.1e-09 35.4 5.1 1.4 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain DUF2208 PF09973.4 EWM24893.1 - 4.3 6.5 7.9 9.2 5.4 0.1 2.7 2 1 1 3 3 3 0 Predicted membrane protein (DUF2208) Lung_7-TM_R PF06814.8 EWM24894.1 - 3.6e-55 186.9 8.9 4.7e-55 186.6 6.2 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.4 EWM24894.1 - 4e-09 36.0 7.4 6.2e-09 35.4 5.1 1.3 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain DUF2208 PF09973.4 EWM24894.1 - 4.5 6.4 7.9 9.3 5.4 0.1 2.6 2 1 1 3 3 3 0 Predicted membrane protein (DUF2208) DUF1997 PF09366.5 EWM24895.1 - 0.0011 18.7 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1997) adh_short PF00106.20 EWM24896.1 - 2.5e-22 79.5 6.7 4.4e-22 78.7 4.4 1.5 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EWM24896.1 - 3.5e-12 46.6 0.1 9.6e-12 45.1 0.1 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EWM24896.1 - 4.4e-10 39.5 4.7 9.7e-10 38.4 3.2 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EWM24896.1 - 0.00099 18.5 0.2 0.0019 17.6 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DNA_pol_lambd_f PF10391.4 EWM24896.1 - 0.11 12.0 0.0 0.28 10.7 0.0 1.6 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda AAA PF00004.24 EWM24897.1 - 1.1e-44 151.8 0.7 5.5e-44 149.5 0.0 2.3 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EWM24897.1 - 2.8e-09 36.8 0.1 9.5e-09 35.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EWM24897.1 - 2.4e-08 34.0 0.9 1.5e-07 31.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EWM24897.1 - 9e-05 22.5 0.0 0.00032 20.7 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EWM24897.1 - 0.00016 21.8 4.8 0.0094 16.1 0.5 3.3 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 EWM24897.1 - 0.00023 19.9 0.0 0.0022 16.7 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus RuvB_N PF05496.7 EWM24897.1 - 0.0003 19.8 0.0 0.00075 18.6 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EWM24897.1 - 0.00033 21.4 0.1 0.0047 17.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 EWM24897.1 - 0.00039 19.4 0.0 0.00088 18.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 EWM24897.1 - 0.00063 19.6 0.0 0.0029 17.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EWM24897.1 - 0.00071 18.8 0.1 0.0016 17.6 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_23 PF13476.1 EWM24897.1 - 0.00083 19.7 0.9 0.86 9.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EWM24897.1 - 0.00089 18.8 0.1 0.0089 15.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EWM24897.1 - 0.0013 18.1 0.5 0.0053 16.1 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein RNA_helicase PF00910.17 EWM24897.1 - 0.0017 18.4 0.0 0.0081 16.3 0.0 2.2 2 0 0 2 2 1 1 RNA helicase Zeta_toxin PF06414.7 EWM24897.1 - 0.0028 16.7 0.0 0.0062 15.6 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_14 PF13173.1 EWM24897.1 - 0.0032 17.3 0.0 0.014 15.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 EWM24897.1 - 0.0035 16.8 0.2 0.15 11.5 0.0 2.9 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_30 PF13604.1 EWM24897.1 - 0.0037 16.8 0.9 0.0072 15.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EWM24897.1 - 0.004 16.8 0.1 0.0099 15.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain NTPase_1 PF03266.10 EWM24897.1 - 0.0051 16.5 0.3 0.059 13.0 0.0 2.6 3 0 0 3 3 3 1 NTPase AAA_28 PF13521.1 EWM24897.1 - 0.0052 16.7 0.2 0.018 15.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EWM24897.1 - 0.0094 15.5 0.2 0.03 13.8 0.2 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EWM24897.1 - 0.012 14.9 5.0 0.17 11.2 0.2 3.2 2 1 1 3 3 3 0 AAA domain DUF3363 PF11843.3 EWM24897.1 - 0.013 14.1 0.3 0.02 13.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3363) NACHT PF05729.7 EWM24897.1 - 0.014 15.0 0.2 0.25 10.9 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Parvo_NS1 PF01057.12 EWM24897.1 - 0.017 14.0 0.0 0.031 13.1 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.6 EWM24897.1 - 0.017 14.6 0.1 0.16 11.5 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IPT PF01745.11 EWM24897.1 - 0.018 14.2 0.1 0.071 12.2 0.0 2.0 2 0 0 2 2 2 0 Isopentenyl transferase UPF0079 PF02367.12 EWM24897.1 - 0.032 13.8 0.0 0.1 12.2 0.0 1.8 1 1 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 EWM24897.1 - 0.043 14.1 0.0 0.25 11.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain KaiC PF06745.8 EWM24897.1 - 0.048 12.7 2.6 0.34 9.9 0.0 2.8 3 0 0 3 3 3 0 KaiC VanY PF02557.12 EWM24897.1 - 0.077 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase GrpE PF01025.14 EWM24897.1 - 0.75 9.3 8.8 0.25 10.8 1.7 2.5 3 0 0 3 3 2 0 GrpE AAA PF00004.24 EWM24898.1 - 2e-44 150.9 1.8 4.8e-44 149.7 0.0 2.4 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EWM24898.1 - 2.4e-09 37.0 0.1 8.4e-09 35.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EWM24898.1 - 2.3e-08 34.1 1.2 1.4e-07 31.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EWM24898.1 - 8e-05 22.7 0.0 0.00029 20.8 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EWM24898.1 - 0.0001 22.4 4.5 0.008 16.3 0.5 3.3 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 EWM24898.1 - 0.0002 20.2 0.0 0.002 16.9 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus RuvB_N PF05496.7 EWM24898.1 - 0.00026 20.0 0.0 0.00067 18.7 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EWM24898.1 - 0.00033 21.4 0.1 0.0042 17.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 EWM24898.1 - 0.00035 19.5 0.0 0.00076 18.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_23 PF13476.1 EWM24898.1 - 0.00044 20.6 0.3 0.78 10.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EWM24898.1 - 0.00063 18.9 0.1 0.0015 17.7 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 EWM24898.1 - 0.00075 19.1 0.1 0.0082 15.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EWM24898.1 - 0.00079 19.3 0.5 0.0029 17.4 0.1 2.2 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EWM24898.1 - 0.0012 18.3 0.5 0.0049 16.3 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein RNA_helicase PF00910.17 EWM24898.1 - 0.0023 18.0 0.0 0.0074 16.4 0.0 1.9 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 EWM24898.1 - 0.0025 16.9 0.0 0.0057 15.7 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 EWM24898.1 - 0.0028 17.1 0.2 0.14 11.6 0.0 2.9 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_14 PF13173.1 EWM24898.1 - 0.0028 17.5 0.0 0.012 15.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EWM24898.1 - 0.0036 17.0 0.1 0.009 15.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EWM24898.1 - 0.0038 16.8 1.1 0.0066 16.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 EWM24898.1 - 0.0041 16.8 0.3 0.053 13.2 0.0 2.7 3 0 0 3 3 3 1 NTPase AAA_28 PF13521.1 EWM24898.1 - 0.0044 16.9 0.1 0.016 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EWM24898.1 - 0.011 15.0 5.1 0.14 11.5 0.1 3.1 2 1 1 3 3 3 0 AAA domain NACHT PF05729.7 EWM24898.1 - 0.012 15.2 0.2 0.23 11.1 0.0 2.5 2 0 0 2 2 2 0 NACHT domain DUF3363 PF11843.3 EWM24898.1 - 0.012 14.2 0.3 0.018 13.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3363) AAA_3 PF07726.6 EWM24898.1 - 0.015 14.8 0.1 0.15 11.6 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 EWM24898.1 - 0.015 14.1 0.0 0.029 13.2 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 IPT PF01745.11 EWM24898.1 - 0.016 14.4 0.1 0.065 12.3 0.0 2.0 2 0 0 2 2 2 0 Isopentenyl transferase AAA_24 PF13479.1 EWM24898.1 - 0.023 14.2 1.7 0.028 14.0 0.2 1.8 2 0 0 2 2 1 0 AAA domain UPF0079 PF02367.12 EWM24898.1 - 0.027 14.0 0.0 0.092 12.3 0.0 1.9 1 1 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 KaiC PF06745.8 EWM24898.1 - 0.031 13.3 2.3 0.31 10.1 0.0 2.9 3 0 0 3 3 3 0 KaiC AAA_18 PF13238.1 EWM24898.1 - 0.036 14.3 0.0 0.23 11.7 0.0 2.3 2 1 0 2 2 2 0 AAA domain GrpE PF01025.14 EWM24898.1 - 0.067 12.7 5.6 0.23 10.9 1.7 2.4 2 0 0 2 2 2 0 GrpE AAA PF00004.24 EWM24899.1 - 1.1e-44 151.7 0.8 4.6e-44 149.8 0.0 2.2 2 1 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EWM24899.1 - 2.2e-09 37.1 0.1 8.1e-09 35.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EWM24899.1 - 1.3e-08 34.9 1.1 1.3e-07 31.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EWM24899.1 - 5.9e-05 23.2 3.9 0.0075 16.4 0.5 3.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EWM24899.1 - 9.6e-05 22.4 0.0 0.00045 20.2 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EWM24899.1 - 0.00025 20.1 0.0 0.00065 18.8 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 EWM24899.1 - 0.00025 20.6 0.2 0.004 16.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EWM24899.1 - 0.00034 19.6 0.0 0.00072 18.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EWM24899.1 - 0.00043 21.0 0.0 0.0054 17.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EWM24899.1 - 0.00054 19.1 0.1 0.0014 17.8 0.1 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_23 PF13476.1 EWM24899.1 - 0.00067 20.0 1.3 0.6 10.4 0.0 2.4 2 1 0 2 2 2 2 AAA domain TIP49 PF06068.8 EWM24899.1 - 0.00087 18.1 0.0 0.002 16.9 0.0 1.6 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EWM24899.1 - 0.00094 19.0 0.6 0.0028 17.5 0.1 2.1 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EWM24899.1 - 0.0011 18.4 0.4 0.0048 16.3 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein RNA_helicase PF00910.17 EWM24899.1 - 0.0024 18.0 0.0 0.0071 16.5 0.0 1.9 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 EWM24899.1 - 0.0025 16.9 0.0 0.0055 15.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 EWM24899.1 - 0.0028 17.1 0.3 0.13 11.7 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_14 PF13173.1 EWM24899.1 - 0.0028 17.5 0.1 0.012 15.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EWM24899.1 - 0.0035 17.0 0.1 0.0088 15.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EWM24899.1 - 0.004 16.7 1.3 0.0064 16.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EWM24899.1 - 0.0054 16.7 0.2 0.016 15.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 EWM24899.1 - 0.0059 16.3 0.1 0.051 13.2 0.0 2.3 2 0 0 2 2 2 1 NTPase IPT PF01745.11 EWM24899.1 - 0.0078 15.4 0.1 0.063 12.4 0.0 2.2 2 0 0 2 2 2 1 Isopentenyl transferase AAA_25 PF13481.1 EWM24899.1 - 0.0093 15.3 5.0 0.13 11.6 0.1 3.1 2 1 1 3 3 3 1 AAA domain NACHT PF05729.7 EWM24899.1 - 0.011 15.4 0.2 0.22 11.1 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_3 PF07726.6 EWM24899.1 - 0.014 14.9 0.1 0.14 11.7 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 EWM24899.1 - 0.015 14.1 0.0 0.028 13.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_24 PF13479.1 EWM24899.1 - 0.024 14.2 1.8 0.027 14.0 0.2 1.8 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EWM24899.1 - 0.026 14.1 0.0 0.089 12.4 0.0 1.9 1 1 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 KaiC PF06745.8 EWM24899.1 - 0.029 13.4 2.5 0.3 10.1 0.0 2.9 3 0 0 3 3 3 0 KaiC DUF3363 PF11843.3 EWM24899.1 - 0.03 12.9 0.3 0.049 12.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3363) AAA_18 PF13238.1 EWM24899.1 - 0.036 14.3 0.0 0.21 11.8 0.0 2.2 2 1 0 2 2 2 0 AAA domain GrpE PF01025.14 EWM24899.1 - 0.059 12.9 6.1 0.17 11.4 2.0 2.3 2 0 0 2 2 2 0 GrpE AFG1_ATPase PF03969.11 EWM24899.1 - 0.086 11.6 0.7 0.24 10.1 0.0 2.0 3 0 0 3 3 2 0 AFG1-like ATPase ADIP PF11559.3 EWM24899.1 - 0.097 12.5 4.0 0.22 11.4 2.8 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding zf-MYND PF01753.13 EWM24900.1 - 8.9e-07 28.6 12.0 2e-06 27.5 8.3 1.6 1 0 0 1 1 1 1 MYND finger Flu_NS2 PF00601.14 EWM24900.1 - 0.11 12.7 0.0 0.53 10.5 0.0 2.1 2 0 0 2 2 2 0 Influenza non-structural protein (NS2) CIA30 PF08547.7 EWM24901.1 - 3e-35 121.4 0.0 4.1e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) NAD_binding_10 PF13460.1 EWM24901.1 - 2e-22 80.0 0.5 1.8e-09 37.8 0.5 3.3 2 1 0 2 2 2 2 NADH(P)-binding NmrA PF05368.8 EWM24901.1 - 2e-07 30.4 0.3 8.7e-06 25.1 0.2 2.7 3 1 0 3 3 3 1 NmrA-like family DapB_N PF01113.15 EWM24901.1 - 0.0015 18.4 0.1 0.0088 15.9 0.1 2.1 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 EWM24901.1 - 0.051 13.0 0.0 0.093 12.1 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EWM24901.1 - 0.064 12.1 0.0 2.2 7.1 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein DUF3049 PF11250.3 EWM24901.1 - 0.091 12.5 0.6 0.19 11.5 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3049) adh_short PF00106.20 EWM24901.1 - 0.19 11.6 2.0 0.37 10.7 0.1 2.3 2 0 0 2 2 2 0 short chain dehydrogenase Transferase PF02458.10 EWM24902.1 - 4.3e-25 88.0 0.0 4.5e-12 45.1 0.0 2.1 2 0 0 2 2 2 2 Transferase family DNA_ligase_A_N PF04675.9 EWM24904.1 - 1.2e-27 96.8 0.0 1.9e-27 96.2 0.0 1.3 1 0 0 1 1 1 1 DNA ligase N terminus Calici_coat PF00915.15 EWM24904.1 - 0.049 12.5 0.1 0.083 11.7 0.1 1.3 1 0 0 1 1 1 0 Calicivirus coat protein zf-MYND PF01753.13 EWM24905.1 - 9.3e-06 25.4 5.1 9.3e-06 25.4 3.5 2.3 2 0 0 2 2 2 1 MYND finger SET PF00856.23 EWM24905.1 - 0.0011 19.3 0.0 0.0023 18.2 0.0 1.5 1 0 0 1 1 1 1 SET domain zf-Mss51 PF13824.1 EWM24905.1 - 0.026 14.3 0.8 0.026 14.3 0.6 2.1 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Mut7-C PF01927.11 EWM24907.1 - 1.3e-31 109.5 0.0 2.5e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 Mut7-C RNAse domain tRNA_edit PF04073.10 EWM24907.1 - 6.3e-11 42.1 0.0 8.2e-09 35.3 0.0 2.4 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain Nop14 PF04147.7 EWM24907.1 - 0.0028 15.6 15.8 0.0039 15.1 10.9 1.1 1 0 0 1 1 1 1 Nop14-like family AAA_23 PF13476.1 EWM24907.1 - 0.0039 17.5 0.2 0.0075 16.6 0.2 1.4 1 1 0 1 1 1 1 AAA domain CobT PF06213.7 EWM24907.1 - 0.0069 15.5 13.5 0.012 14.8 9.4 1.3 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT TFIIA PF03153.8 EWM24907.1 - 0.064 13.1 7.6 0.094 12.6 5.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Daxx PF03344.10 EWM24907.1 - 0.3 9.5 23.1 0.49 8.8 16.0 1.2 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 EWM24907.1 - 0.48 9.6 16.1 0.78 8.9 11.2 1.3 1 0 0 1 1 1 0 SDA1 Mpp10 PF04006.7 EWM24907.1 - 0.67 8.2 19.9 0.98 7.6 13.8 1.1 1 0 0 1 1 1 0 Mpp10 protein DDHD PF02862.12 EWM24907.1 - 0.83 9.4 2.9 1.6 8.4 2.0 1.4 1 0 0 1 1 1 0 DDHD domain CDC45 PF02724.9 EWM24907.1 - 1.4 6.8 11.5 2.2 6.1 8.0 1.2 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rpc4 PF05132.9 EWM24907.1 - 1.7 8.6 6.9 3.9 7.4 4.8 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 VID27 PF08553.5 EWM24907.1 - 1.8 6.7 16.0 2.5 6.2 11.1 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Paf1 PF03985.8 EWM24907.1 - 3.4 6.2 24.3 6.3 5.4 16.9 1.3 1 0 0 1 1 1 0 Paf1 NOA36 PF06524.7 EWM24907.1 - 3.5 6.7 11.1 6.5 5.9 7.7 1.3 1 0 0 1 1 1 0 NOA36 protein Trypan_PARP PF05887.6 EWM24907.1 - 3.6 7.3 27.1 0.069 12.9 13.5 2.0 3 0 0 3 3 2 0 Procyclic acidic repetitive protein (PARP) DUF1510 PF07423.6 EWM24907.1 - 6.1 6.1 16.6 11 5.2 11.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Leu_zip PF15294.1 EWM24908.1 - 0.00034 19.8 3.2 0.00054 19.1 2.2 1.2 1 0 0 1 1 1 1 Leucine zipper CENP-H PF05837.7 EWM24908.1 - 0.13 12.4 0.3 0.13 12.4 0.2 2.5 2 1 1 3 3 3 0 Centromere protein H (CENP-H) CCDC155 PF14662.1 EWM24908.1 - 0.61 9.6 10.3 0.044 13.3 2.8 2.2 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 DivIC PF04977.10 EWM24908.1 - 0.65 9.5 16.3 0.26 10.8 0.5 4.2 3 1 0 4 4 4 0 Septum formation initiator TMF_DNA_bd PF12329.3 EWM24908.1 - 1 9.1 13.3 6.9 6.5 0.1 4.2 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF904 PF06005.7 EWM24908.1 - 2.2 8.6 13.0 1.4 9.2 2.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF904) DUF972 PF06156.8 EWM24908.1 - 2.6 8.4 9.1 16 5.8 0.2 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Lebercilin PF15619.1 EWM24908.1 - 4.6 6.5 14.0 17 4.7 0.3 2.7 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Ribul_P_3_epim PF00834.14 EWM24910.1 - 1.5e-91 305.0 0.1 1.7e-91 304.7 0.1 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.14 EWM24910.1 - 3.2e-07 30.0 0.0 0.00017 21.1 0.0 2.2 2 0 0 2 2 2 2 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.16 EWM24910.1 - 0.011 14.9 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein PcrB PF01884.12 EWM24910.1 - 0.039 13.1 0.2 0.1 11.8 0.1 1.7 1 1 0 1 1 1 0 PcrB family TMP-TENI PF02581.12 EWM24910.1 - 0.07 12.2 0.1 0.25 10.4 0.0 1.8 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI PGM_PMM_II PF02879.11 EWM24910.1 - 0.093 13.0 0.0 13 6.1 0.0 2.5 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II FA_desaturase PF00487.19 EWM24911.1 - 3.1e-25 89.0 18.5 6.9e-25 87.9 12.8 1.5 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EWM24911.1 - 9.4e-08 32.1 0.0 2.2e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Thioredoxin PF00085.15 EWM24912.1 - 7.3e-20 70.5 0.0 1.3e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin PUB PF09409.5 EWM24912.1 - 3.9e-10 39.3 0.0 8.4e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 PUB domain UBA PF00627.26 EWM24912.1 - 2.6e-05 23.9 3.3 0.034 14.0 0.2 3.7 3 0 0 3 3 3 1 UBA/TS-N domain Thioredoxin_7 PF13899.1 EWM24912.1 - 0.028 14.4 0.0 0.078 13.0 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.1 EWM24912.1 - 0.061 13.5 0.0 0.42 10.8 0.0 2.3 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EWM24912.1 - 0.09 12.8 0.0 0.22 11.6 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin-like MGDG_synth PF06925.6 EWM24913.1 - 8.4e-31 107.1 0.0 1.2e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 Monogalactosyldiacylglycerol (MGDG) synthase Glyco_tran_28_C PF04101.11 EWM24913.1 - 3.7e-10 39.7 0.0 5.8e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EWM24913.1 - 1.9e-05 24.0 0.0 0.039 13.1 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 1 Glyco_trans_1_4 PF13692.1 EWM24913.1 - 0.021 14.9 0.0 0.054 13.6 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 Chloroa_b-bind PF00504.16 EWM24914.1 - 1.2e-38 132.8 0.1 1.5e-38 132.5 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein NAD_binding_8 PF13450.1 EWM24917.1 - 8.4e-05 22.5 0.0 0.00018 21.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EWM24917.1 - 0.00054 19.1 0.2 0.11 11.5 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.9 EWM24917.1 - 0.0067 14.9 0.0 0.011 14.2 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 EWM24917.1 - 0.01 16.2 0.2 0.052 13.9 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EWM24917.1 - 0.019 15.0 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EWM24917.1 - 0.044 13.5 0.1 0.09 12.5 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding DAO PF01266.19 EWM24917.1 - 0.05 12.5 0.7 0.05 12.5 0.5 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EWM24917.1 - 0.13 12.1 0.2 0.2 11.4 0.1 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ArfGap PF01412.13 EWM24918.1 - 3.2e-34 117.1 0.0 4.9e-34 116.6 0.0 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ank_4 PF13637.1 EWM24918.1 - 4.8e-13 49.2 0.1 1.3e-07 31.9 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EWM24918.1 - 4.5e-12 46.1 0.2 8.2e-12 45.3 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EWM24918.1 - 1.7e-10 40.1 0.6 3.3e-07 29.7 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EWM24918.1 - 2.1e-09 37.3 0.7 1.4e-07 31.5 0.1 2.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM24918.1 - 7e-07 28.8 0.1 2e-05 24.3 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat BiPBP_C PF06832.7 EWM24918.1 - 0.051 13.5 0.1 0.09 12.7 0.0 1.3 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family HCV_capsid PF01543.12 EWM24918.1 - 0.13 12.2 0.1 0.85 9.6 0.0 2.0 2 0 0 2 2 2 0 Hepatitis C virus capsid protein C2 PF00168.25 EWM24919.1 - 4.2e-05 23.2 0.0 6.4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 C2 domain DUF4440 PF14534.1 EWM24920.1 - 1.5e-10 41.2 0.4 2e-10 40.7 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) CaMKII_AD PF08332.5 EWM24920.1 - 3.3e-10 39.9 0.0 4.4e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II Association SnoaL_3 PF13474.1 EWM24920.1 - 6.8e-10 39.0 0.1 1e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.2 EWM24920.1 - 0.00013 22.2 0.3 0.00024 21.4 0.2 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.1 EWM24920.1 - 0.00039 20.3 0.4 0.00059 19.7 0.3 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EWM24921.1 - 4.4e-10 39.7 1.0 8.5e-10 38.8 0.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4440) CaMKII_AD PF08332.5 EWM24921.1 - 1.4e-09 37.9 0.0 2e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II Association SnoaL_3 PF13474.1 EWM24921.1 - 2.3e-09 37.3 0.2 4.5e-09 36.3 0.1 1.6 2 0 0 2 2 2 1 SnoaL-like domain SnoaL_2 PF12680.2 EWM24921.1 - 0.00046 20.5 0.3 0.00092 19.5 0.2 1.4 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.1 EWM24921.1 - 0.0013 18.6 0.4 0.0024 17.7 0.3 1.4 1 0 0 1 1 1 1 SnoaL-like domain DUF1395 PF07160.7 EWM24922.1 - 0.022 14.2 0.2 0.052 13.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1395) DNA_ligase_A_C PF04679.10 EWM24923.1 - 1.5e-20 73.3 0.0 2.3e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_A_C PF04679.10 EWM24924.1 - 2.6e-20 72.6 0.0 4.2e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA12 PF10443.4 EWM24925.1 - 0.058 11.8 0.0 0.076 11.4 0.0 1.2 1 0 0 1 1 1 0 RNA12 protein Pkinase PF00069.20 EWM24926.1 - 2e-32 112.3 0.0 1.7e-20 73.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EWM24926.1 - 2.6e-15 56.2 0.0 9.3e-10 38.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EWM24926.1 - 0.00032 20.5 0.0 0.0012 18.6 0.0 2.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EWM24926.1 - 0.0004 19.4 0.0 0.00071 18.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Prenyltransf PF01255.14 EWM24927.1 - 3.9e-69 232.1 0.0 4.8e-69 231.8 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Clathrin PF00637.15 EWM24928.1 - 0.00013 21.5 0.0 0.056 13.0 0.0 2.5 2 1 0 2 2 2 2 Region in Clathrin and VPS VPS11_C PF12451.3 EWM24929.1 - 2.5e-05 24.0 0.1 6.4e-05 22.7 0.1 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal Ribosomal_60s PF00428.14 EWM24929.1 - 0.0071 16.7 4.6 0.024 15.0 3.2 1.9 1 0 0 1 1 1 1 60s Acidic ribosomal protein DNA_pol_phi PF04931.8 EWM24929.1 - 2.1 6.0 5.3 3 5.4 3.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi Ribosomal_L1 PF00687.16 EWM24932.1 - 6.7e-43 146.5 0.0 9e-43 146.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Serinc PF03348.10 EWM24934.1 - 4.6e-58 196.9 8.0 6.2e-58 196.5 5.6 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) ABC_tran PF00005.22 EWM24935.1 - 2.2e-08 34.5 0.0 3e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EWM24935.1 - 1.6e-05 25.0 0.0 2e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 EWM24935.1 - 0.15 12.0 0.2 2.5 8.0 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Peptidase_C12 PF01088.16 EWM24936.1 - 1.3e-26 93.0 0.0 4.5e-26 91.3 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Proteasome PF00227.21 EWM24937.1 - 4.1e-35 120.7 0.0 5.1e-35 120.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit UCH PF00443.24 EWM24938.1 - 2.2e-12 46.6 0.0 4.3e-12 45.7 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EWM24938.1 - 0.00034 20.1 0.0 0.43 9.9 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase SRP54 PF00448.17 EWM24939.1 - 2e-53 180.7 0.0 3.5e-53 179.9 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 EWM24939.1 - 2.7e-23 82.7 0.0 4.4e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.14 EWM24939.1 - 4.3e-08 33.1 0.2 1.3e-07 31.5 0.0 1.9 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 EWM24939.1 - 2.2e-07 29.9 0.1 9.6e-07 27.8 0.1 1.9 1 1 0 1 1 1 1 ArgK protein AAA_30 PF13604.1 EWM24939.1 - 3.5e-06 26.7 0.1 7.8e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 EWM24939.1 - 6.8e-06 25.6 0.3 1.9e-05 24.1 0.2 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 EWM24939.1 - 8.6e-05 22.2 0.4 0.0016 18.1 0.1 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EWM24939.1 - 9.4e-05 22.4 0.2 0.00079 19.4 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EWM24939.1 - 0.00016 21.7 0.0 0.0014 18.7 0.0 2.4 1 1 1 2 2 2 1 AAA domain NTPase_1 PF03266.10 EWM24939.1 - 0.0002 21.0 0.6 0.18 11.4 0.0 2.7 2 1 0 3 3 3 2 NTPase Zeta_toxin PF06414.7 EWM24939.1 - 0.0041 16.2 0.0 0.0087 15.1 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_10 PF12846.2 EWM24939.1 - 0.0082 15.6 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain ETF PF01012.16 EWM24939.1 - 0.015 14.9 0.7 0.058 13.1 0.2 2.1 2 0 0 2 2 2 0 Electron transfer flavoprotein domain DAP3 PF10236.4 EWM24939.1 - 0.03 13.2 0.0 0.052 12.4 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Fer4_NifH PF00142.13 EWM24939.1 - 0.038 13.1 0.0 0.097 11.8 0.0 1.7 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CoA_binding_2 PF13380.1 EWM24939.1 - 0.041 14.0 0.2 0.79 9.9 0.0 2.5 2 1 0 2 2 2 0 CoA binding domain AAA PF00004.24 EWM24939.1 - 0.042 14.0 0.0 0.13 12.4 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EWM24939.1 - 0.044 13.6 0.0 0.17 11.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EWM24939.1 - 0.068 13.1 0.1 0.24 11.3 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase 6PF2K PF01591.13 EWM24939.1 - 0.12 11.3 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase FTCD PF02971.9 EWM24939.1 - 0.25 10.9 0.0 0.25 10.9 0.0 2.1 3 0 0 3 3 1 0 Formiminotransferase domain Nop14 PF04147.7 EWM24939.1 - 0.51 8.1 2.6 0.67 7.7 1.8 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1469 PF07332.6 EWM24941.1 - 0.78 9.4 5.1 1.2 8.9 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Peptidase_S24 PF00717.18 EWM24942.1 - 6.7e-11 41.6 0.2 1.1e-10 41.0 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like DUF504 PF04457.7 EWM24942.1 - 0.072 13.2 1.2 0.14 12.3 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF504) AMP-binding PF00501.23 EWM24944.1 - 2.7e-73 246.7 0.0 4.7e-73 245.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EWM24944.1 - 2.3e-64 217.2 3.2 5.7e-64 216.0 2.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EWM24944.1 - 6.9e-55 186.6 0.3 1.2e-54 185.8 0.2 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EWM24944.1 - 2e-50 170.9 0.4 4.9e-50 169.7 0.3 1.7 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EWM24944.1 - 3.3e-42 144.2 1.8 9e-42 142.8 0.3 2.6 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EWM24944.1 - 4.7e-40 136.1 0.6 2.2e-39 133.9 0.2 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EWM24944.1 - 9.9e-16 57.7 0.0 1.4e-07 31.6 0.0 3.7 3 0 0 3 3 3 2 Phosphopantetheine attachment site Condensation PF00668.15 EWM24944.1 - 3.3e-12 45.8 0.0 1.7e-09 36.9 0.0 2.2 2 0 0 2 2 2 2 Condensation domain Hexapep PF00132.19 EWM24944.1 - 1.2e-05 24.6 12.8 0.003 16.9 0.2 6.8 5 2 2 8 8 8 1 Bacterial transferase hexapeptide (six repeats) Thiolase_N PF00108.18 EWM24944.1 - 0.011 14.7 0.1 0.021 13.8 0.1 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain Polysacc_synt_2 PF02719.10 EWM24944.1 - 0.77 8.6 0.0 1.3 7.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sucrose_synth PF00862.14 EWM24944.1 - 2 6.3 0.0 3.6 5.4 0.0 1.3 1 0 0 1 1 1 0 Sucrose synthase ATP_bind_4 PF01902.12 EWM24946.1 - 1.1e-37 129.5 0.0 2.1e-37 128.6 0.0 1.5 1 0 0 1 1 1 1 ATP-binding region Ribonuc_L-PSP PF01042.16 EWM24946.1 - 2.4e-23 82.1 0.0 8.3e-10 38.4 0.0 4.1 4 0 0 4 4 4 3 Endoribonuclease L-PSP UCH PF00443.24 EWM24947.1 - 7.4e-46 156.4 0.0 1.1e-44 152.5 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EWM24947.1 - 7.3e-17 61.7 0.0 3.9e-10 39.6 0.0 2.9 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 EWM24947.1 - 1.1e-13 50.5 5.7 3.3e-10 39.4 0.5 2.5 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP PF02148.14 EWM24947.1 - 2e-09 37.4 0.0 7.2e-09 35.6 0.0 2.0 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UBA_4 PF14555.1 EWM24947.1 - 0.053 13.0 2.1 0.067 12.7 0.2 2.1 2 0 0 2 2 2 0 UBA-like domain Myb_DNA-binding PF00249.26 EWM24948.1 - 1.6e-23 82.4 3.7 4.2e-11 42.7 0.0 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EWM24948.1 - 4.1e-21 74.8 3.6 7.7e-15 54.7 0.5 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.3 EWM24948.1 - 0.088 12.6 0.6 6.3 6.7 0.1 2.6 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Zip PF02535.17 EWM24948.1 - 1.5 7.7 23.3 0.77 8.6 3.0 2.4 2 0 0 2 2 2 0 ZIP Zinc transporter Glycos_transf_3 PF00591.16 EWM24949.1 - 7.3e-86 287.6 1.1 9e-86 287.3 0.8 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 EWM24949.1 - 1.3e-16 59.9 0.3 3.3e-16 58.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain Pentapeptide PF00805.17 EWM24950.1 - 6.2e-18 63.6 4.6 2.6e-08 32.8 0.2 3.3 2 1 1 3 3 3 3 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 EWM24950.1 - 2e-17 62.7 6.7 3.4e-10 39.5 1.6 2.1 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 EWM24950.1 - 1.1e-08 34.7 6.4 1.2e-06 28.3 0.3 3.0 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) S-AdoMet_synt_C PF02773.11 EWM24950.1 - 0.15 11.7 0.3 0.37 10.4 0.1 1.7 1 1 0 1 1 1 0 S-adenosylmethionine synthetase, C-terminal domain PPR PF01535.15 EWM24951.1 - 8.1e-08 31.7 6.8 0.39 10.8 0.1 7.4 8 0 0 8 8 8 2 PPR repeat PPR_2 PF13041.1 EWM24951.1 - 0.00013 21.8 1.2 23 5.0 0.0 5.8 6 1 0 6 6 6 1 PPR repeat family PPR_3 PF13812.1 EWM24951.1 - 0.016 15.4 17.3 4.2 7.9 0.0 8.5 10 0 0 10 10 10 0 Pentatricopeptide repeat domain TPR_14 PF13428.1 EWM24951.1 - 0.023 15.3 9.3 4.2 8.2 0.1 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Smr PF01713.16 EWM24951.1 - 0.038 14.1 0.2 0.41 10.8 0.0 2.5 2 0 0 2 2 2 0 Smr domain TPR_19 PF14559.1 EWM24951.1 - 0.097 13.0 0.8 0.79 10.1 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TRAM_LAG1_CLN8 PF03798.11 EWM24954.1 - 1.8e-15 57.0 16.1 1.8e-15 57.0 11.2 1.4 2 0 0 2 2 2 1 TLC domain zf-C3HC4_2 PF13923.1 EWM24955.1 - 3.4e-06 26.9 14.8 8e-06 25.7 10.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EWM24955.1 - 3.8e-06 26.4 14.0 7.7e-06 25.4 9.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EWM24955.1 - 1.9e-05 24.2 11.9 3.7e-05 23.3 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EWM24955.1 - 3e-05 23.6 13.1 5.8e-05 22.7 9.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EWM24955.1 - 0.00036 20.2 11.9 0.00073 19.3 8.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.1 EWM24955.1 - 0.021 14.6 5.1 0.042 13.6 3.5 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EWM24955.1 - 4.6 7.0 9.7 20 5.0 6.4 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EWM24955.1 - 6.7 6.6 12.4 14 5.6 8.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING UFC1 PF08694.6 EWM24956.1 - 1.9e-71 238.7 0.0 2.3e-71 238.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.21 EWM24956.1 - 0.00089 18.7 0.1 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF1415 PF07209.7 EWM24957.1 - 1.4e-25 90.0 0.0 3.2e-25 88.8 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1415) Mito_carr PF00153.22 EWM24958.1 - 1e-19 69.9 8.5 8.8e-07 28.5 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein TPR_11 PF13414.1 EWM24959.1 - 1.7e-11 43.6 0.6 1.7e-11 43.6 0.4 2.1 2 0 0 2 2 2 1 TPR repeat DUF4470 PF14737.1 EWM24959.1 - 1.5e-06 27.8 0.0 7.8e-06 25.5 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) TPR_16 PF13432.1 EWM24959.1 - 0.00015 22.3 1.8 0.0012 19.5 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EWM24959.1 - 0.0012 18.6 2.5 0.0082 15.9 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EWM24959.1 - 0.0016 17.9 0.0 0.0066 16.0 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EWM24959.1 - 0.0056 17.2 0.8 1.9 9.3 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EWM24959.1 - 0.056 13.2 0.1 0.91 9.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 EWM24959.1 - 0.058 13.2 3.4 0.062 13.1 0.4 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat adh_short PF00106.20 EWM24961.1 - 6.5e-24 84.7 3.3 1.6e-23 83.4 2.3 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EWM24961.1 - 5.5e-08 32.6 0.8 8.4e-08 32.0 0.6 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EWM24961.1 - 6.2e-05 22.8 0.2 0.00013 21.7 0.1 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EWM24961.1 - 0.004 16.9 0.3 0.0089 15.8 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 EWM24961.1 - 0.02 14.0 0.0 0.065 12.3 0.0 1.8 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EWM24961.1 - 0.052 13.5 0.3 0.2 11.6 0.1 1.9 2 0 0 2 2 2 0 NADH(P)-binding DFP PF04127.10 EWM24961.1 - 0.064 12.8 0.1 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Cas1_AcylT PF07779.7 EWM24962.1 - 1.5e-88 297.4 17.1 2e-88 297.0 11.9 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.1 EWM24962.1 - 3.5e-13 49.9 0.0 6.5e-13 49.0 0.0 1.5 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Lipase_GDSL_2 PF13472.1 EWM24962.1 - 0.0027 17.8 0.0 0.0047 17.0 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family SNF2_N PF00176.18 EWM24963.1 - 7.2e-25 87.3 0.0 1.2e-24 86.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EWM24963.1 - 9.6e-08 31.7 0.0 2.3e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Na_Ca_ex PF01699.19 EWM24964.1 - 1.2e-09 37.9 26.2 2.4e-09 36.9 10.5 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein EF-hand_1 PF00036.27 EWM24964.1 - 5e-09 34.8 0.8 3.6e-07 29.0 0.4 2.5 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 EWM24964.1 - 3.1e-08 33.6 0.1 5.9e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EWM24964.1 - 5.7e-07 28.8 1.4 0.00033 20.3 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EWM24964.1 - 3.4e-05 23.3 0.1 7.8e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 EWM24964.1 - 0.0028 16.9 3.7 0.013 14.7 0.3 2.7 3 0 0 3 3 3 1 EF hand RVT_3 PF13456.1 EWM24965.1 - 2.8e-27 94.3 2.6 1.2e-24 85.9 0.3 2.7 2 1 0 2 2 2 2 Reverse transcriptase-like RNase_H PF00075.19 EWM24965.1 - 4.8e-10 39.8 0.0 8.9e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 RNase H Myb_DNA-binding PF00249.26 EWM24966.1 - 4.4e-24 84.2 4.4 1.6e-11 44.0 1.3 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EWM24966.1 - 3.2e-11 43.1 4.8 0.00016 21.7 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain TRAPP PF04051.11 EWM24968.1 - 5.4e-32 110.4 0.0 6.7e-32 110.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Cu_amine_oxid PF01179.15 EWM24968.1 - 0.11 11.1 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Copper amine oxidase, enzyme domain Proteasome PF00227.21 EWM24969.1 - 2.7e-34 118.1 0.0 3.2e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit ATP_bind_3 PF01171.15 EWM24970.1 - 3.2e-44 150.6 0.0 1e-21 77.2 0.0 2.2 2 0 0 2 2 2 2 PP-loop family TilS_C PF11734.3 EWM24970.1 - 1e-06 27.8 0.5 1e-06 27.8 0.3 2.7 3 0 0 3 3 3 1 TilS substrate C-terminal domain PAPS_reduct PF01507.14 EWM24970.1 - 4e-05 23.5 0.0 6.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Asn_synthase PF00733.16 EWM24970.1 - 0.0032 16.9 0.6 0.011 15.1 0.0 2.0 2 0 0 2 2 2 1 Asparagine synthase DUF3670 PF12419.3 EWM24970.1 - 0.0072 15.7 2.9 1.3 8.4 0.0 3.1 3 0 0 3 3 3 2 SNF2 Helicase protein TilS PF09179.6 EWM24970.1 - 0.14 12.2 6.4 0.48 10.4 4.3 2.1 1 1 0 1 1 1 0 TilS substrate binding domain CDtoxinA PF03498.9 EWM24970.1 - 0.19 11.1 0.0 0.35 10.2 0.0 1.4 1 0 0 1 1 1 0 Cytolethal distending toxin A/C family Xpo1 PF08389.7 EWM24971.1 - 1.6e-14 54.0 0.0 2.4e-13 50.2 0.0 2.5 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.14 EWM24971.1 - 3.4e-06 26.8 0.0 9.4e-06 25.4 0.0 1.8 1 0 0 1 1 1 1 Importin-beta N-terminal domain Sec6 PF06046.8 EWM24972.1 - 5.8e-48 163.3 4.1 8.6e-48 162.7 2.8 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 Sec7_N PF12783.2 EWM24972.1 - 0.00048 19.6 0.5 0.053 12.9 0.1 2.6 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal WD40 PF00400.27 EWM24973.1 - 3.7e-09 36.1 0.1 7.9e-05 22.3 0.0 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat Nop PF01798.13 EWM24974.1 - 3.4e-60 201.6 0.7 3.4e-60 201.6 0.5 1.8 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 EWM24974.1 - 6.8e-28 96.2 0.1 1.2e-27 95.4 0.1 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EWM24974.1 - 9e-23 80.2 0.3 3.1e-22 78.5 0.2 2.0 1 0 0 1 1 1 1 NOP5NT (NUC127) domain DUF1678 PF07913.6 EWM24974.1 - 0.038 13.5 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1678) LAT PF15234.1 EWM24975.1 - 0.03 13.8 3.6 0.046 13.2 2.5 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells eIF3_subunit PF08597.5 EWM24975.1 - 0.037 13.5 2.2 0.051 13.1 1.5 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Daxx PF03344.10 EWM24975.1 - 0.059 11.8 2.9 0.067 11.6 2.0 1.1 1 0 0 1 1 1 0 Daxx Family DUF2890 PF11081.3 EWM24975.1 - 0.083 12.9 6.1 0.13 12.3 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) CENP-B_dimeris PF09026.5 EWM24975.1 - 0.21 11.8 8.0 0.5 10.6 5.5 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 EWM24975.1 - 0.37 11.1 14.5 0.18 12.1 6.5 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.7 EWM24975.1 - 0.56 8.0 7.9 0.67 7.8 5.5 1.1 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.1 EWM24975.1 - 1.1 8.9 3.8 2 8.0 2.6 1.4 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.7 EWM24975.1 - 1.3 8.2 2.7 1.9 7.6 1.9 1.2 1 0 0 1 1 1 0 NOA36 protein Paf1 PF03985.8 EWM24975.1 - 3.4 6.2 7.8 4.7 5.8 5.4 1.1 1 0 0 1 1 1 0 Paf1 VID27 PF08553.5 EWM24975.1 - 4.8 5.2 5.1 6.4 4.8 3.5 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein S-methyl_trans PF02574.11 EWM24976.1 - 5.4e-87 291.9 0.0 9.1e-87 291.1 0.0 1.4 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Met_synt_B12 PF02965.12 EWM24976.1 - 1.2e-74 250.1 0.0 2e-74 249.3 0.0 1.4 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain Pterin_bind PF00809.17 EWM24976.1 - 3.8e-39 134.2 0.3 8.7e-39 133.0 0.2 1.7 1 0 0 1 1 1 1 Pterin binding enzyme B12-binding_2 PF02607.12 EWM24976.1 - 4.8e-21 74.5 1.4 2.1e-20 72.5 0.0 2.9 4 0 0 4 4 4 1 B12 binding domain B12-binding PF02310.14 EWM24976.1 - 5e-17 61.8 0.5 4.7e-16 58.7 0.2 2.7 2 0 0 2 2 2 1 B12 binding domain Cpn60_TCP1 PF00118.19 EWM24977.1 - 8.8e-112 374.1 7.3 1e-111 373.9 5.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sigma54_activ_2 PF14532.1 EWM24977.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain IF4E PF01652.13 EWM24978.1 - 3.9e-46 156.5 0.1 5.1e-46 156.2 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E IF4E PF01652.13 EWM24979.1 - 3.6e-42 143.7 0.1 4.2e-42 143.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF2247 PF10004.4 EWM24979.1 - 0.14 11.9 0.2 0.46 10.1 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2247) TATR PF03430.8 EWM24980.1 - 1.9 7.0 2.7 2.9 6.4 1.9 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator NMD3 PF04981.8 EWM24981.1 - 1.5e-62 210.7 4.5 2e-62 210.3 3.1 1.2 1 0 0 1 1 1 1 NMD3 family Aldo_ket_red PF00248.16 EWM24982.1 - 1.5e-55 188.0 0.0 1.8e-55 187.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ribosomal_S18 PF01084.15 EWM24983.1 - 2.9e-17 62.2 0.4 9.9e-17 60.5 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S18 Chorion_2 PF03964.10 EWM24983.1 - 0.066 13.7 1.7 0.12 12.9 1.2 1.4 1 0 0 1 1 1 0 Chorion family 2 Ribosomal_S18 PF01084.15 EWM24984.1 - 4e-17 61.8 0.0 6.2e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S18 O-FucT PF10250.4 EWM24985.1 - 0.0053 15.9 0.2 5.9 5.9 0.1 3.5 3 1 0 3 3 3 2 GDP-fucose protein O-fucosyltransferase Cupin_2 PF07883.6 EWM24986.1 - 1.2e-09 37.4 2.1 0.00013 21.3 0.0 3.0 2 1 0 2 2 2 2 Cupin domain Cupin_1 PF00190.17 EWM24986.1 - 5e-06 26.0 0.0 0.0019 17.6 0.0 2.4 2 0 0 2 2 2 2 Cupin Cupin_3 PF05899.7 EWM24986.1 - 0.017 14.5 0.0 0.045 13.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Cpn10 PF00166.16 EWM24988.1 - 2.4e-44 149.1 0.5 1.9e-21 75.8 0.3 2.1 2 0 0 2 2 2 2 Chaperonin 10 Kd subunit TPR_12 PF13424.1 EWM24989.1 - 2.5e-20 72.1 7.5 8.7e-09 35.1 0.1 4.4 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EWM24989.1 - 2.1e-15 56.1 7.7 4.9e-08 32.5 0.0 3.8 4 0 0 4 4 4 2 TPR repeat TPR_1 PF00515.23 EWM24989.1 - 4.5e-13 48.2 8.6 9.4e-05 21.8 0.0 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EWM24989.1 - 2e-12 47.4 9.9 2.7e-05 24.7 0.0 5.4 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 EWM24989.1 - 1.2e-10 40.4 15.3 0.004 16.9 0.0 6.1 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 EWM24989.1 - 2e-10 40.3 11.7 0.028 15.0 0.0 7.8 7 1 1 8 8 8 2 Tetratricopeptide repeat Apc3 PF12895.2 EWM24989.1 - 3.5e-08 33.4 3.2 0.0025 17.8 0.0 3.8 4 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EWM24989.1 - 9.4e-08 31.3 3.6 0.034 13.9 0.0 5.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 EWM24989.1 - 4e-06 27.0 0.5 0.031 14.6 0.0 3.6 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 EWM24989.1 - 1.6e-05 24.6 14.8 0.02 14.8 0.1 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EWM24989.1 - 2.4e-05 24.4 9.9 0.022 15.1 0.1 5.7 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_4 PF07721.9 EWM24989.1 - 3.3e-05 23.8 0.5 1.2 9.7 0.0 4.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EWM24989.1 - 3.9e-05 23.5 6.5 0.72 10.1 0.0 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EWM24989.1 - 7.6e-05 22.2 10.4 0.39 10.6 0.1 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_21 PF09976.4 EWM24989.1 - 0.00025 20.9 3.0 0.013 15.3 0.1 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EWM24989.1 - 0.019 14.8 0.9 4.5 7.2 0.1 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat NARP1 PF12569.3 EWM24989.1 - 0.094 11.4 2.5 8.8 4.9 0.0 3.1 2 1 1 3 3 3 0 NMDA receptor-regulated protein 1 RPN7 PF10602.4 EWM24989.1 - 0.097 12.0 0.3 0.34 10.2 0.0 2.1 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TPR_3 PF07720.7 EWM24989.1 - 0.14 12.0 0.5 3.1 7.6 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.15 EWM24989.1 - 0.83 9.7 10.9 23 5.2 0.0 5.7 7 0 0 7 7 5 0 PPR repeat TPR_12 PF13424.1 EWM24990.1 - 2.5e-20 72.1 7.5 8.7e-09 35.1 0.1 4.4 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EWM24990.1 - 2.1e-15 56.1 7.7 4.9e-08 32.5 0.0 3.8 4 0 0 4 4 4 2 TPR repeat TPR_1 PF00515.23 EWM24990.1 - 4.5e-13 48.2 8.6 9.4e-05 21.8 0.0 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EWM24990.1 - 2e-12 47.4 9.9 2.7e-05 24.7 0.0 5.4 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 EWM24990.1 - 1.2e-10 40.4 15.3 0.004 16.9 0.0 6.1 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 EWM24990.1 - 2e-10 40.3 11.7 0.028 15.0 0.0 7.8 7 1 1 8 8 8 2 Tetratricopeptide repeat Apc3 PF12895.2 EWM24990.1 - 3.5e-08 33.4 3.2 0.0025 17.8 0.0 3.8 4 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EWM24990.1 - 9.4e-08 31.3 3.6 0.034 13.9 0.0 5.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 EWM24990.1 - 4e-06 27.0 0.5 0.031 14.6 0.0 3.6 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 EWM24990.1 - 1.6e-05 24.6 14.8 0.02 14.8 0.1 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EWM24990.1 - 2.4e-05 24.4 9.9 0.022 15.1 0.1 5.7 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_4 PF07721.9 EWM24990.1 - 3.3e-05 23.8 0.5 1.2 9.7 0.0 4.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EWM24990.1 - 3.9e-05 23.5 6.5 0.72 10.1 0.0 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EWM24990.1 - 7.6e-05 22.2 10.4 0.39 10.6 0.1 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_21 PF09976.4 EWM24990.1 - 0.00025 20.9 3.0 0.013 15.3 0.1 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EWM24990.1 - 0.019 14.8 0.9 4.5 7.2 0.1 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat NARP1 PF12569.3 EWM24990.1 - 0.094 11.4 2.5 8.8 4.9 0.0 3.1 2 1 1 3 3 3 0 NMDA receptor-regulated protein 1 RPN7 PF10602.4 EWM24990.1 - 0.097 12.0 0.3 0.34 10.2 0.0 2.1 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TPR_3 PF07720.7 EWM24990.1 - 0.14 12.0 0.5 3.1 7.6 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.15 EWM24990.1 - 0.83 9.7 10.9 23 5.2 0.0 5.7 7 0 0 7 7 5 0 PPR repeat MIF PF01187.13 EWM24991.1 - 7.5e-18 64.6 0.0 1.2e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.16 EWM24991.1 - 2.4e-05 23.8 0.0 0.061 12.9 0.0 2.3 2 0 0 2 2 2 2 Tautomerase enzyme zf-HIT PF04438.11 EWM24992.1 - 1.7e-06 27.5 14.8 1.7e-06 27.5 10.2 1.6 2 0 0 2 2 2 1 HIT zinc finger Pkinase PF00069.20 EWM24993.1 - 1.7e-71 240.4 0.0 1.9e-71 240.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM24993.1 - 5e-40 137.2 0.0 6.1e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EWM24993.1 - 1.5e-06 27.3 0.0 7.3e-06 25.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EWM24993.1 - 0.023 14.4 0.3 0.11 12.1 0.0 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EWM24993.1 - 0.12 11.8 0.1 6.4 6.2 0.0 2.1 1 1 1 2 2 2 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.6 EWM24993.1 - 0.21 10.3 0.0 0.31 9.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PepSY_TM_3 PF13706.1 EWM24994.1 - 0.086 12.2 0.4 0.17 11.2 0.3 1.5 1 0 0 1 1 1 0 PepSY-associated TM helix PepSY_TM_3 PF13706.1 EWM24996.1 - 0.049 13.0 0.2 0.081 12.3 0.2 1.4 1 0 0 1 1 1 0 PepSY-associated TM helix Adaptin_N PF01602.15 EWM24997.1 - 6.8e-110 367.8 0.0 8.2e-110 367.5 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 EWM24997.1 - 3.5e-16 59.1 0.0 6.6e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 EWM24997.1 - 9.9e-16 58.0 0.0 1.8e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT PF02985.17 EWM24997.1 - 0.001 18.9 1.1 2.6 8.3 0.0 3.9 3 0 0 3 3 3 1 HEAT repeat Cnd1 PF12717.2 EWM24997.1 - 0.02 14.7 0.1 2 8.2 0.0 2.4 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.4 EWM24997.1 - 0.072 11.3 0.0 0.11 10.6 0.0 1.2 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit Choline_transpo PF04515.7 EWM24998.1 - 9.3e-59 198.8 27.3 9.3e-59 198.8 18.9 2.0 2 0 0 2 2 2 1 Plasma-membrane choline transporter HR_lesion PF05514.6 EWM24998.1 - 0.53 10.1 7.5 0.051 13.3 1.1 2.3 2 0 0 2 2 2 0 HR-like lesion-inducing Glyco_hydro_79n PF03662.9 EWM24999.1 - 4.8e-91 304.7 0.0 6.2e-91 304.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 79, N-terminal domain W2 PF02020.13 EWM25000.1 - 1.5e-14 53.6 0.1 1.5e-14 53.6 0.0 2.0 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon DUF3121 PF11319.3 EWM25000.1 - 1.8 8.0 5.0 3.2 7.2 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3121) Gar1 PF04410.9 EWM25001.1 - 2.1e-25 88.9 0.1 3e-25 88.4 0.1 1.3 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region PhoD PF09423.5 EWM25003.1 - 6.5e-18 64.5 0.0 1.6e-17 63.2 0.0 1.5 1 1 0 1 1 1 1 PhoD-like phosphatase Lant_dehyd_N PF04737.8 EWM25003.1 - 0.072 13.1 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Lantibiotic dehydratase, N terminus Ribul_P_3_epim PF00834.14 EWM25004.1 - 7.4e-68 227.6 0.0 8.6e-68 227.4 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family PG_binding_3 PF09374.5 EWM25004.1 - 0.043 13.7 0.0 0.094 12.7 0.0 1.5 1 0 0 1 1 1 0 Predicted Peptidoglycan domain OMPdecase PF00215.19 EWM25004.1 - 0.052 12.9 0.0 0.54 9.6 0.0 2.1 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Reo_sigmaC PF04582.7 EWM25005.1 - 2.2 7.3 16.1 0.29 10.2 0.7 3.7 3 1 1 4 4 4 0 Reovirus sigma C capsid protein USP8_interact PF08941.5 EWM25005.1 - 3.5 6.9 15.9 0.061 12.6 2.4 3.6 2 1 0 3 3 3 0 USP8 interacting ABC1 PF03109.11 EWM25006.1 - 1.6e-21 76.4 0.0 2.8e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 EWM25006.1 - 0.0014 18.3 0.5 0.0034 17.1 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EWM25006.1 - 0.053 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Zn_ribbon_recom PF13408.1 EWM25007.1 - 0.37 11.0 7.5 0.55 10.5 5.2 1.3 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-C2H2 PF00096.21 EWM25008.1 - 5.5e-16 57.8 25.5 2.6e-05 24.2 1.2 4.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EWM25008.1 - 3.3e-12 45.8 17.0 0.00043 20.4 0.5 5.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EWM25008.1 - 2.9e-08 33.5 8.4 9.3e-07 28.8 0.2 5.2 6 0 0 6 6 4 2 Zinc-finger double domain Nop14 PF04147.7 EWM25008.1 - 0.0013 16.8 11.5 0.0017 16.3 8.0 1.1 1 0 0 1 1 1 1 Nop14-like family CobT PF06213.7 EWM25008.1 - 0.0098 15.0 8.4 0.015 14.4 5.8 1.2 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT CHORD PF04968.7 EWM25008.1 - 0.01 16.0 10.8 1.1 9.5 0.3 4.4 3 1 1 4 4 4 0 CHORD Raftlin PF15250.1 EWM25008.1 - 0.035 12.6 4.0 0.05 12.1 2.7 1.1 1 0 0 1 1 1 0 Raftlin SAPS PF04499.10 EWM25008.1 - 0.067 11.8 3.9 0.085 11.4 2.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein zf-TRAF PF02176.13 EWM25008.1 - 0.21 11.9 9.3 0.15 12.4 0.8 3.3 3 0 0 3 3 3 0 TRAF-type zinc finger DUF1795 PF08786.6 EWM25008.1 - 0.22 11.3 6.7 1 9.2 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1795) Daxx PF03344.10 EWM25008.1 - 0.44 8.9 15.7 0.62 8.4 10.9 1.1 1 0 0 1 1 1 0 Daxx Family Vfa1 PF08432.5 EWM25008.1 - 0.84 9.6 11.0 1.3 9.0 7.6 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 zf-C2H2_2 PF12756.2 EWM25008.1 - 0.96 9.5 12.3 0.1 12.7 2.2 3.6 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) Pox_Ag35 PF03286.9 EWM25008.1 - 1.1 8.7 7.7 1.9 7.9 5.4 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Sporozoite_P67 PF05642.6 EWM25008.1 - 1.1 7.0 12.3 0.017 13.0 3.2 1.7 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Myc_N PF01056.13 EWM25008.1 - 1.2 8.2 8.6 0.53 9.3 4.0 1.7 2 0 0 2 2 2 0 Myc amino-terminal region DUF2890 PF11081.3 EWM25008.1 - 1.3 9.0 12.7 3.2 7.7 8.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Paf1 PF03985.8 EWM25008.1 - 1.4 7.5 17.2 2 7.0 11.9 1.1 1 0 0 1 1 1 0 Paf1 NOA36 PF06524.7 EWM25008.1 - 1.7 7.8 10.8 0.029 13.6 2.1 1.9 2 0 0 2 2 2 0 NOA36 protein CDC45 PF02724.9 EWM25008.1 - 2.2 6.2 15.3 3 5.7 10.6 1.1 1 0 0 1 1 1 0 CDC45-like protein U79_P34 PF03064.11 EWM25008.1 - 2.7 7.4 13.4 4.7 6.6 9.3 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF1510 PF07423.6 EWM25008.1 - 3.4 6.9 13.2 5 6.4 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FYDLN_acid PF09538.5 EWM25008.1 - 5.2 7.6 14.1 5.1 7.7 8.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Nucleoplasmin PF03066.10 EWM25008.1 - 7.2 6.1 14.0 13 5.3 9.7 1.3 1 0 0 1 1 1 0 Nucleoplasmin FAM176 PF14851.1 EWM25008.1 - 7.4 6.2 9.6 15 5.2 6.7 1.5 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.1 EWM25008.1 - 9 6.6 11.9 20 5.5 8.2 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Hid1 PF12722.2 EWM25008.1 - 9.3 3.7 9.0 13 3.3 6.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAP PF02037.22 EWM25009.1 - 5.5e-14 51.2 4.4 1.1e-13 50.2 3.0 1.6 1 0 0 1 1 1 1 SAP domain HeH PF12949.2 EWM25009.1 - 0.00049 19.5 0.6 0.0014 18.1 0.4 1.9 1 1 0 1 1 1 1 HeH/LEM domain Telomere_Sde2_2 PF13297.1 EWM25009.1 - 0.053 12.7 1.4 0.19 11.0 0.9 2.0 1 0 0 1 1 1 0 Telomere stability C-terminal DUF4245 PF14030.1 EWM25009.1 - 0.15 11.7 0.2 0.15 11.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4245) TPR_11 PF13414.1 EWM25010.1 - 1.7e-30 104.4 20.9 4.8e-13 48.5 0.4 7.2 4 2 3 7 7 7 6 TPR repeat DnaJ PF00226.26 EWM25010.1 - 6.3e-23 80.2 3.6 6.3e-23 80.2 2.5 2.9 3 1 0 3 3 2 1 DnaJ domain TPR_16 PF13432.1 EWM25010.1 - 2.9e-21 75.5 22.3 4e-07 30.5 0.8 6.2 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EWM25010.1 - 1.9e-19 67.9 26.2 4.5e-06 26.1 0.0 9.7 11 1 1 12 12 11 5 Tetratricopeptide repeat TPR_1 PF00515.23 EWM25010.1 - 2e-18 65.1 9.7 6.1e-06 25.6 0.0 7.7 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 EWM25010.1 - 1.4e-15 57.3 16.1 3.8e-06 27.1 1.1 5.8 3 3 3 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 EWM25010.1 - 6.6e-14 51.1 23.6 0.15 12.7 0.0 9.0 4 3 5 9 9 9 4 Tetratricopeptide repeat Apc3 PF12895.2 EWM25010.1 - 2.5e-10 40.3 9.1 0.0013 18.8 0.0 4.5 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 EWM25010.1 - 2.5e-09 36.8 1.2 0.72 9.7 0.0 5.2 4 1 1 5 5 5 3 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.1 EWM25010.1 - 9.1e-09 34.4 15.1 0.0013 18.4 0.0 7.0 7 1 0 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 EWM25010.1 - 9.9e-08 31.8 24.0 0.52 10.2 0.0 7.0 4 3 2 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 EWM25010.1 - 1.2e-07 31.3 4.7 0.36 11.1 0.0 7.0 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 EWM25010.1 - 1.6e-06 27.4 8.8 0.99 9.3 0.2 7.4 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 EWM25010.1 - 2.8e-06 27.0 12.6 0.23 11.3 0.1 5.5 3 3 3 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.9 EWM25010.1 - 4.6e-05 23.4 7.1 0.85 10.2 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 EWM25010.1 - 0.1 12.5 9.6 12 6.0 0.1 5.5 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_3 PF07720.7 EWM25010.1 - 0.22 11.3 4.2 4.6 7.1 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 EWM25010.1 - 0.24 11.5 12.6 1.7 8.8 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EWM25010.1 - 0.67 10.5 25.9 21 5.8 0.1 8.7 10 0 0 10 10 8 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EWM25010.1 - 0.7 10.1 11.0 1.5 9.0 0.0 4.5 3 3 3 6 6 6 0 Alkyl sulfatase dimerisation TOM20_plant PF06552.7 EWM25010.1 - 1.7 8.2 5.8 3.8 7.0 0.1 3.3 2 1 2 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 NARP1 PF12569.3 EWM25010.1 - 7.4 5.2 19.3 2.7 6.6 0.0 4.5 3 1 3 6 6 6 0 NMDA receptor-regulated protein 1 mTERF PF02536.9 EWM25011.1 - 2.3e-28 98.8 0.0 1.1e-15 57.1 0.0 2.1 1 1 1 2 2 2 2 mTERF HTH_31 PF13560.1 EWM25011.1 - 0.0029 17.7 1.3 1.3 9.2 0.0 4.2 3 0 0 3 3 3 1 Helix-turn-helix domain Gp37 PF09646.5 EWM25011.1 - 0.038 13.4 0.0 0.072 12.5 0.0 1.3 1 0 0 1 1 1 0 Gp37 protein IATP PF04568.7 EWM25013.1 - 0.1 12.6 1.6 0.15 12.1 1.1 1.3 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP Inhibitor_I29 PF08246.7 EWM25013.1 - 2.3 8.5 5.0 0.46 10.8 1.0 1.7 2 0 0 2 2 2 0 Cathepsin propeptide inhibitor domain (I29) zf-BED PF02892.10 EWM25014.1 - 0.022 14.5 1.3 0.14 11.9 0.1 2.2 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.1 EWM25014.1 - 0.1 12.5 5.5 0.6 10.0 0.6 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Dus PF01207.12 EWM25015.1 - 8.7e-67 225.1 0.0 1.1e-66 224.8 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 EWM25015.1 - 8e-05 22.0 0.0 0.00014 21.1 0.0 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.10 EWM25015.1 - 0.028 13.5 0.0 0.055 12.6 0.0 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase TMP-TENI PF02581.12 EWM25015.1 - 0.048 12.7 0.0 0.084 11.9 0.0 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI WD40 PF00400.27 EWM25016.1 - 4.1e-60 197.6 35.2 1.7e-11 43.4 1.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nbas_N PF15492.1 EWM25016.1 - 0.014 14.5 0.0 3.8 6.5 0.0 2.8 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal SH3_9 PF14604.1 EWM25016.1 - 0.026 14.1 0.9 0.047 13.2 0.1 1.9 2 0 0 2 2 2 0 Variant SH3 domain Arm PF00514.18 EWM25018.1 - 9.6e-51 167.9 27.5 2.6e-11 42.8 0.0 8.9 8 1 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EWM25018.1 - 3.3e-21 75.3 0.6 2.2e-07 31.0 0.0 5.4 2 2 3 5 5 5 5 HEAT repeats HEAT_EZ PF13513.1 EWM25018.1 - 1.8e-16 60.0 4.0 8.3e-06 26.1 0.0 5.6 5 0 0 5 5 5 3 HEAT-like repeat HEAT PF02985.17 EWM25018.1 - 5.3e-12 44.7 7.8 0.0071 16.3 0.0 7.5 8 0 0 8 8 8 3 HEAT repeat Proteasom_PSMB PF10508.4 EWM25018.1 - 2e-05 23.0 0.0 0.083 11.1 0.0 2.4 3 0 0 3 3 3 2 Proteasome non-ATPase 26S subunit Arm_2 PF04826.8 EWM25018.1 - 0.0071 15.4 0.0 4.5 6.3 0.0 2.4 2 1 1 3 3 3 3 Armadillo-like V-ATPase_H_C PF11698.3 EWM25018.1 - 0.034 14.0 0.0 0.96 9.3 0.0 2.8 3 0 0 3 3 3 0 V-ATPase subunit H Adaptin_N PF01602.15 EWM25018.1 - 0.21 9.8 0.0 0.54 8.5 0.0 1.7 1 1 0 1 1 1 0 Adaptin N terminal region Nucleotid_trans PF03407.11 EWM25019.1 - 3e-28 99.0 0.0 3.5e-24 85.7 0.0 2.5 1 1 1 2 2 2 2 Nucleotide-diphospho-sugar transferase Cupin_8 PF13621.1 EWM25021.1 - 6.6e-14 52.0 0.0 9.3e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EWM25021.1 - 1.9e-08 34.5 0.0 1.8e-07 31.3 0.0 2.2 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 EWM25021.1 - 0.0034 16.6 0.0 0.0085 15.3 0.0 1.7 2 0 0 2 2 2 1 Cupin superfamily protein GPI PF06560.6 EWM25021.1 - 0.023 13.7 0.0 0.04 12.9 0.0 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) AAA_11 PF13086.1 EWM25022.1 - 1.6e-12 47.5 0.0 2.8e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EWM25022.1 - 8.5e-11 41.4 0.0 1.9e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EWM25022.1 - 9.5e-07 28.5 0.0 1.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.9 EWM25022.1 - 0.0001 21.3 0.0 0.00015 20.8 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase ResIII PF04851.10 EWM25022.1 - 0.00029 20.7 0.0 0.00044 20.1 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.1 EWM25022.1 - 0.0028 17.6 0.0 0.0055 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EWM25022.1 - 0.0041 17.3 0.0 0.007 16.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SNF2_N PF00176.18 EWM25022.1 - 0.0045 15.8 0.0 0.0069 15.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EWM25022.1 - 0.0058 16.1 0.0 0.0095 15.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EWM25022.1 - 0.086 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain UPF0262 PF06793.7 EWM25022.1 - 0.11 12.2 0.2 0.52 10.0 0.0 2.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0262) UvrD-helicase PF00580.16 EWM25022.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DUF2075 PF09848.4 EWM25022.1 - 0.31 9.9 0.0 1.3 7.9 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) GST_C_3 PF14497.1 EWM25023.1 - 7.8e-08 32.7 0.0 1.5e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EWM25023.1 - 0.00014 21.6 0.2 0.00036 20.3 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain CTP_transf_2 PF01467.21 EWM25024.1 - 4.8e-22 78.6 0.0 1e-21 77.5 0.0 1.6 1 0 0 1 1 1 1 Cytidylyltransferase Ashwin PF15323.1 EWM25024.1 - 4.5 7.2 12.3 7 6.5 8.5 1.3 1 0 0 1 1 1 0 Developmental protein FBPase PF00316.15 EWM25027.1 - 5.8e-81 271.8 0.0 7.2e-81 271.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase UMP1 PF05348.6 EWM25028.1 - 1.9e-23 82.8 0.0 2.2e-23 82.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 DOPA_dioxygen PF08883.6 EWM25028.1 - 0.12 12.5 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Dopa 4,5-dioxygenase family UAF_Rrn10 PF05234.6 EWM25030.1 - 0.031 14.3 0.0 0.074 13.0 0.0 1.6 1 0 0 1 1 1 0 UAF complex subunit Rrn10 MaoC_dehydratas PF01575.14 EWM25031.1 - 1.5e-13 50.2 0.4 1.8e-12 46.7 0.1 2.2 2 0 0 2 2 2 1 MaoC like domain Lamprin PF06403.6 EWM25031.1 - 0.0024 17.6 0.7 0.0024 17.6 0.5 1.8 2 0 0 2 2 2 1 Lamprin MaoC_dehydrat_N PF13452.1 EWM25031.1 - 0.0025 17.5 0.0 1.3 8.7 0.0 2.3 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase DUF457 PF04307.9 EWM25031.1 - 0.025 13.9 0.1 0.038 13.3 0.1 1.4 1 0 0 1 1 1 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) PNPOx_C PF10590.4 EWM25034.1 - 2.8e-19 68.3 2.3 6.3e-19 67.2 1.6 1.6 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 EWM25034.1 - 1.3e-18 66.8 0.0 6.5e-13 48.5 0.0 2.5 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase DUF572 PF04502.8 EWM25035.1 - 9e-47 159.8 0.0 1.4e-46 159.2 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) SnoaL_3 PF13474.1 EWM25036.1 - 1e-07 31.9 0.1 1.9e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.2 EWM25036.1 - 0.00069 19.9 0.0 0.0023 18.2 0.0 2.0 2 1 0 2 2 2 1 SnoaL-like domain NTF2 PF02136.15 EWM25036.1 - 0.0008 19.7 0.0 0.003 17.9 0.0 1.9 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain CaMKII_AD PF08332.5 EWM25036.1 - 0.013 15.4 1.6 0.033 14.0 1.1 1.8 1 1 0 1 1 1 0 Calcium/calmodulin dependent protein kinase II Association SnoaL_4 PF13577.1 EWM25036.1 - 0.038 13.8 0.2 0.13 12.1 0.1 1.9 1 1 0 1 1 1 0 SnoaL-like domain SIMPL PF04402.9 EWM25036.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF541) TINF2_N PF14973.1 EWM25036.1 - 0.19 11.8 0.5 3.5 7.7 0.0 2.2 2 0 0 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus SnoaL_3 PF13474.1 EWM25037.1 - 5.7e-08 32.8 0.1 1e-07 32.0 0.1 1.4 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.2 EWM25037.1 - 0.00047 20.5 0.1 0.0013 19.0 0.1 1.8 1 1 0 1 1 1 1 SnoaL-like domain NTF2 PF02136.15 EWM25037.1 - 0.001 19.4 0.0 0.0018 18.6 0.0 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain CaMKII_AD PF08332.5 EWM25037.1 - 0.0069 16.2 1.5 0.018 14.9 1.0 1.8 1 1 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II Association SnoaL_4 PF13577.1 EWM25037.1 - 0.021 14.7 0.4 0.083 12.8 0.2 1.9 1 1 0 1 1 1 0 SnoaL-like domain SIMPL PF04402.9 EWM25037.1 - 0.084 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF541) XPG_I PF00867.13 EWM25038.1 - 1.5e-24 85.8 0.0 3.2e-24 84.7 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EWM25038.1 - 1.7e-20 73.1 0.0 1.5e-19 70.0 0.0 2.2 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I_2 PF12813.2 EWM25038.1 - 8.1e-05 22.2 1.3 0.00015 21.3 0.9 1.4 1 0 0 1 1 1 1 XPG domain containing Hydrolase_4 PF12146.3 EWM25039.1 - 1e-22 79.7 0.4 2.6e-22 78.4 0.3 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 EWM25039.1 - 5.9e-21 75.3 2.0 7.7e-21 75.0 1.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM25039.1 - 2.5e-15 56.4 0.0 6.4e-15 55.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EWM25039.1 - 2.8e-05 24.4 0.1 4.8e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.15 EWM25039.1 - 4.7e-05 23.0 0.4 0.00037 20.1 0.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EWM25039.1 - 0.00016 21.1 0.1 0.0045 16.4 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DUF2305 PF10230.4 EWM25039.1 - 0.013 14.9 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Esterase PF00756.15 EWM25039.1 - 0.021 14.2 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Putative esterase PGAP1 PF07819.8 EWM25039.1 - 0.029 13.9 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 EWM25039.1 - 0.058 13.0 0.1 0.099 12.2 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF900 PF05990.7 EWM25039.1 - 0.061 12.6 0.0 0.085 12.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.10 EWM25039.1 - 0.14 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF2905 PF11146.3 EWM25040.1 - 5.7e-09 35.7 0.5 7.8e-09 35.3 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2905) TPR_16 PF13432.1 EWM25040.1 - 2e-05 25.1 2.0 0.00019 21.9 2.7 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EWM25040.1 - 0.00026 20.5 0.7 0.00047 19.7 0.5 1.4 1 0 0 1 1 1 1 TPR repeat Myc_N PF01056.13 EWM25041.1 - 0.00045 19.5 0.1 0.00067 18.9 0.1 1.2 1 0 0 1 1 1 1 Myc amino-terminal region Ribosomal_60s PF00428.14 EWM25041.1 - 0.0021 18.3 3.5 0.0021 18.3 2.4 2.3 3 0 0 3 3 3 1 60s Acidic ribosomal protein CDC45 PF02724.9 EWM25041.1 - 0.18 9.8 2.9 0.24 9.3 2.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 EWM25041.1 - 4.2 6.8 7.6 7.6 6.0 5.3 1.3 1 0 0 1 1 1 0 Nucleoplasmin DEAD PF00270.24 EWM25042.1 - 4.6e-34 117.3 0.0 1.1e-33 116.1 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EWM25042.1 - 6.1e-14 51.6 0.0 2.4e-13 49.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EWM25042.1 - 7.3e-05 22.7 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain SecA_DEAD PF07517.9 EWM25042.1 - 0.0034 16.7 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 2 SecA DEAD-like domain SNF2_N PF00176.18 EWM25042.1 - 0.0064 15.3 0.0 0.0093 14.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EWM25042.1 - 0.011 15.6 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Kelch_3 PF13415.1 EWM25042.1 - 0.06 13.5 0.0 0.22 11.7 0.0 2.0 2 0 0 2 2 2 0 Galactose oxidase, central domain CMS1 PF14617.1 EWM25042.1 - 0.14 11.1 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Glyco_tranf_2_3 PF13641.1 EWM25045.1 - 1e-36 126.9 0.0 1.5e-36 126.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Cellulose_synt PF03552.9 EWM25045.1 - 1.7e-28 99.3 6.3 6.8e-15 54.4 1.0 3.3 1 1 2 3 3 3 3 Cellulose synthase Glyco_trans_2_3 PF13632.1 EWM25045.1 - 4.8e-20 72.0 0.7 4.8e-20 72.0 0.5 2.2 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EWM25045.1 - 7.4e-15 55.0 0.0 1.8e-14 53.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EWM25045.1 - 2.9e-12 46.2 0.0 7.6e-12 44.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.10 EWM25045.1 - 8.1e-05 21.1 0.2 0.11 10.9 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_2 PF10111.4 EWM25045.1 - 0.021 13.9 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 DUF373 PF04123.8 EWM25045.1 - 0.12 11.3 0.7 0.26 10.2 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Peptidase_C1 PF00112.18 EWM25047.1 - 3.5e-48 164.3 0.4 5.1e-48 163.8 0.3 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EWM25047.1 - 2.6e-06 27.5 0.1 4.6e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) TFIIA_gamma_N PF02268.11 EWM25049.1 - 5.4e-06 25.8 0.0 8.1e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain Sipho_Gp157 PF05565.6 EWM25049.1 - 0.0028 17.2 0.1 0.0044 16.6 0.1 1.2 1 0 0 1 1 1 1 Siphovirus Gp157 ADH_N PF08240.7 EWM25050.1 - 1.7e-33 114.5 0.8 3.3e-33 113.7 0.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EWM25050.1 - 8.7e-23 80.2 0.7 1.5e-22 79.4 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EWM25050.1 - 0.00017 22.4 0.1 0.00044 21.1 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EWM25051.1 - 1.7e-33 114.5 0.8 3.3e-33 113.7 0.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EWM25051.1 - 8.7e-23 80.2 0.7 1.5e-22 79.4 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EWM25051.1 - 0.00017 22.4 0.1 0.00044 21.1 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ORC3_N PF07034.6 EWM25053.1 - 1.8e-14 53.4 0.2 3.2e-14 52.6 0.2 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus Sulfate_transp PF00916.15 EWM25054.1 - 1.7e-31 109.3 2.1 3e-31 108.4 1.5 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EWM25054.1 - 6.8e-26 89.7 2.6 6.8e-26 89.7 1.8 3.2 3 1 1 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif E1-E2_ATPase PF00122.15 EWM25054.1 - 0.62 9.0 0.0 0.62 9.0 0.0 2.3 3 0 0 3 3 3 0 E1-E2 ATPase SdpI PF13630.1 EWM25054.1 - 1.2 8.9 5.7 13 5.6 0.0 2.8 2 0 0 2 2 2 0 SdpI/YhfL protein family DUF2975 PF11188.3 EWM25054.1 - 1.7 8.3 8.2 0.68 9.6 0.1 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2975) Glycolytic PF00274.14 EWM25056.1 - 8.2e-127 422.3 0.0 1e-126 422.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Glycolytic PF00274.14 EWM25057.1 - 6.9e-127 422.6 0.0 8.4e-127 422.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Cnd1 PF12717.2 EWM25058.1 - 3.4e-54 183.3 2.5 5.2e-48 163.2 0.0 5.3 5 1 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.2 EWM25058.1 - 1.5e-06 27.4 0.4 1.1e-05 24.5 0.1 2.4 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Adaptin_N PF01602.15 EWM25058.1 - 5.3e-05 21.7 1.5 5.3e-05 21.7 1.0 3.1 3 1 0 3 3 3 1 Adaptin N terminal region HEAT PF02985.17 EWM25058.1 - 0.00035 20.4 20.4 0.8 9.9 0.2 8.1 8 0 0 8 8 8 2 HEAT repeat HEAT_2 PF13646.1 EWM25058.1 - 0.0035 17.5 5.4 0.025 14.8 0.6 5.8 4 2 1 5 5 5 3 HEAT repeats Lsm_C PF14894.1 EWM25058.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Lsm C-terminal Cohesin_HEAT PF12765.2 EWM25058.1 - 0.23 11.4 12.7 0.43 10.5 0.3 4.7 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.1 EWM25058.1 - 0.39 11.2 26.6 0.72 10.4 0.2 8.3 8 1 0 8 8 8 0 HEAT-like repeat DUF202 PF02656.10 EWM25059.1 - 6.5e-16 58.3 0.5 2.7e-15 56.3 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) MscS_TM PF12794.2 EWM25059.1 - 0.0089 14.6 1.6 0.01 14.4 1.1 1.0 1 0 0 1 1 1 1 Mechanosensitive ion channel inner membrane domain 1 Clc-like PF07062.7 EWM25059.1 - 0.077 12.2 3.2 0.19 10.9 2.2 1.5 1 1 0 1 1 1 0 Clc-like Pkinase PF00069.20 EWM25060.1 - 1.5e-54 184.8 4.1 1.6e-54 184.8 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain adh_short PF00106.20 EWM25060.1 - 2.5e-26 92.5 1.0 8.2e-26 90.8 0.7 2.0 1 0 0 1 1 1 1 short chain dehydrogenase Pkinase_Tyr PF07714.12 EWM25060.1 - 2e-24 86.0 0.0 6e-24 84.5 0.0 1.9 1 0 0 1 1 1 1 Protein tyrosine kinase adh_short_C2 PF13561.1 EWM25060.1 - 1.4e-12 47.9 0.1 2.5e-12 47.1 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Aph-1 PF06105.7 EWM25062.1 - 7.5e-37 126.8 15.9 9.1e-37 126.5 11.0 1.0 1 0 0 1 1 1 1 Aph-1 protein Amastin PF07344.6 EWM25062.1 - 0.011 15.4 3.7 0.011 15.4 2.6 2.4 1 1 1 2 2 2 0 Amastin surface glycoprotein MtN3_slv PF03083.11 EWM25062.1 - 0.33 10.8 5.1 0.1 12.4 0.8 2.2 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange DUF3087 PF11286.3 EWM25062.1 - 3 7.0 6.3 0.36 10.0 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) JAB PF01398.16 EWM25063.1 - 4.9e-37 126.1 0.1 1e-36 125.1 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EWM25063.1 - 1.4e-27 96.0 1.9 1.4e-27 96.0 1.3 2.2 3 0 0 3 3 3 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EWM25063.1 - 3.9e-07 29.5 0.0 6.5e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain PI3_PI4_kinase PF00454.22 EWM25064.1 - 3.8e-46 157.4 0.0 9e-45 152.9 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EWM25064.1 - 2.7e-44 150.5 0.0 4.5e-44 149.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.19 EWM25064.1 - 2.3e-08 33.9 0.0 5.6e-08 32.6 0.0 1.7 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.1 EWM25064.1 - 0.17 10.8 0.0 0.32 9.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Toprim_N PF08275.6 EWM25065.1 - 2.7e-29 101.7 0.0 5.1e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 DNA primase catalytic core, N-terminal domain zf-CHC2 PF01807.15 EWM25065.1 - 5.6e-29 99.5 0.0 1.7e-28 97.9 0.0 1.8 1 0 0 1 1 1 1 CHC2 zinc finger Toprim_4 PF13662.1 EWM25065.1 - 4.3e-13 49.0 0.1 8.3e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Toprim_2 PF13155.1 EWM25065.1 - 2.8e-07 30.7 0.0 9.6e-07 29.0 0.0 2.0 1 0 0 1 1 1 1 Toprim-like Toprim_3 PF13362.1 EWM25065.1 - 5.1e-05 23.4 0.0 0.0001 22.4 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Toprim PF01751.17 EWM25065.1 - 0.00052 19.9 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 Toprim domain MRP_L53 PF10780.4 EWM25065.1 - 0.012 15.6 0.0 0.43 10.5 0.0 2.7 2 0 0 2 2 2 0 39S ribosomal protein L53/MRP-L53 FadA PF09403.5 EWM25065.1 - 0.98 9.4 8.9 4.4 7.3 0.5 2.3 2 0 0 2 2 2 0 Adhesion protein FadA CTD PF12815.2 EWM25066.1 - 5.4e-10 39.7 22.6 1.6e-06 28.5 6.9 2.7 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.24 EWM25066.1 - 5.6e-10 38.5 14.4 0.0026 17.3 0.0 5.6 5 0 0 5 5 5 4 KOW motif Spt5-NGN PF03439.8 EWM25066.1 - 6.5e-08 32.2 0.5 1.6e-07 30.9 0.3 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 EWM25066.1 - 6.3e-05 23.5 10.5 6.3e-05 23.5 7.3 4.5 3 1 1 4 4 4 1 Spt5 transcription elongation factor, acidic N-terminal YajC PF02699.10 EWM25066.1 - 0.9 9.2 4.0 0.83 9.3 0.0 2.9 3 0 0 3 3 3 0 Preprotein translocase subunit Daxx PF03344.10 EWM25066.1 - 4.2 5.7 28.1 8.7 4.6 19.5 1.5 1 0 0 1 1 1 0 Daxx Family Cation_efflux PF01545.16 EWM25067.1 - 9.1e-38 129.9 0.6 9.1e-38 129.9 0.4 1.5 2 0 0 2 2 2 1 Cation efflux family Glyco_transf_8C PF08437.5 EWM25067.1 - 4 7.5 7.1 33 4.6 0.4 3.1 3 0 0 3 3 3 0 Glycosyl transferase family 8 C-terminal SMC_Nse1 PF07574.8 EWM25068.1 - 1.2e-17 64.2 3.0 1.3e-14 54.3 0.6 2.0 1 1 0 2 2 2 2 Nse1 non-SMC component of SMC5-6 complex zf-DBF PF07535.7 EWM25068.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 DBF zinc finger Mannitol_dh_C PF08125.8 EWM25069.1 - 9e-06 25.0 0.4 0.031 13.4 0.1 3.4 2 2 1 3 3 3 2 Mannitol dehydrogenase C-terminal domain SF-assemblin PF06705.6 EWM25070.1 - 0.0047 16.1 0.1 0.007 15.5 0.1 1.1 1 0 0 1 1 1 1 SF-assemblin/beta giardin IF-2B PF01008.12 EWM25071.1 - 1.7e-65 220.8 0.0 1.9e-65 220.6 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family ArfGap PF01412.13 EWM25072.1 - 6.7e-31 106.4 0.0 7.7e-31 106.3 0.0 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Tubulin PF00091.20 EWM25073.1 - 3.6e-37 128.2 0.5 7.9e-37 127.1 0.4 1.6 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.3 EWM25073.1 - 6.2e-33 112.7 1.0 2.6e-32 110.7 0.2 2.3 2 0 0 2 2 2 1 FtsZ family, C-terminal domain WD40 PF00400.27 EWM25073.1 - 3.8e-18 64.5 10.6 3.4e-05 23.5 0.4 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat AAA_2 PF07724.9 EWM25075.1 - 3e-35 121.6 0.0 4.7e-35 121.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EWM25075.1 - 1e-14 54.8 0.0 1.6e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EWM25075.1 - 3.2e-06 27.3 0.2 1.6e-05 25.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EWM25075.1 - 5.6e-05 22.8 0.8 0.00056 19.6 0.6 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EWM25075.1 - 5.8e-05 22.3 0.1 0.00049 19.3 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EWM25075.1 - 0.00011 23.0 0.0 0.0002 22.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EWM25075.1 - 0.00011 21.2 0.0 0.00094 18.2 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 EWM25075.1 - 0.00032 20.2 0.1 0.0042 16.5 0.1 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain MCM PF00493.18 EWM25075.1 - 0.00036 19.4 0.2 0.00098 18.0 0.1 1.7 2 1 0 2 2 2 1 MCM2/3/5 family AAA_33 PF13671.1 EWM25075.1 - 0.00052 19.9 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EWM25075.1 - 0.0013 18.7 0.7 0.006 16.5 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain T2SE PF00437.15 EWM25075.1 - 0.0022 16.9 0.0 0.0047 15.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Sigma54_activ_2 PF14532.1 EWM25075.1 - 0.0024 17.9 0.0 0.015 15.3 0.0 2.2 1 1 1 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 EWM25075.1 - 0.0035 16.7 0.1 0.0075 15.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein ABC_tran PF00005.22 EWM25075.1 - 0.0056 16.9 0.1 0.012 15.9 0.0 1.7 2 0 0 2 2 1 1 ABC transporter AAA_18 PF13238.1 EWM25075.1 - 0.011 16.0 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EWM25075.1 - 0.019 14.8 0.0 0.046 13.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 EWM25075.1 - 0.019 14.4 0.0 0.083 12.3 0.0 1.8 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_19 PF13245.1 EWM25075.1 - 0.025 14.3 1.0 0.07 12.9 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 EWM25075.1 - 0.033 13.8 0.5 0.093 12.3 0.3 1.8 1 1 0 1 1 1 0 NACHT domain AAA_24 PF13479.1 EWM25075.1 - 0.037 13.6 0.1 0.066 12.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EWM25075.1 - 0.065 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein UPF0079 PF02367.12 EWM25075.1 - 0.089 12.4 0.1 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 EWM25075.1 - 0.09 12.2 0.4 0.21 10.9 0.1 1.7 2 0 0 2 2 2 0 AAA-like domain AAA_28 PF13521.1 EWM25075.1 - 0.11 12.4 0.2 0.49 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 EWM25075.1 - 0.12 10.9 0.0 0.23 10.0 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain PH PF00169.24 EWM25077.1 - 0.12 12.5 0.0 0.32 11.2 0.0 1.8 1 1 0 1 1 1 0 PH domain Pkinase PF00069.20 EWM25079.1 - 3.1e-33 115.0 0.0 1e-31 110.0 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM25079.1 - 1.4e-21 76.7 0.0 2.4e-19 69.4 0.0 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3972 PF13118.1 EWM25079.1 - 0.1 12.7 0.6 0.21 11.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3972) Robl_LC7 PF03259.12 EWM25080.1 - 1e-13 50.6 0.0 1.2e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain CLPTM1 PF05602.7 EWM25080.1 - 0.074 11.7 0.0 0.08 11.6 0.0 1.0 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) MoaE PF02391.12 EWM25081.1 - 2.1e-34 117.8 0.1 2.7e-34 117.4 0.1 1.1 1 0 0 1 1 1 1 MoaE protein CTP_transf_2 PF01467.21 EWM25082.1 - 1.2e-11 44.8 0.0 2.2e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase FAD_syn PF06574.7 EWM25082.1 - 0.045 13.3 0.0 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 FAD synthetase PDZ PF00595.19 EWM25084.1 - 5.7e-07 29.6 0.0 0.012 15.7 0.0 2.3 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EWM25084.1 - 2.6e-06 27.2 0.0 0.019 14.8 0.0 2.3 2 0 0 2 2 2 2 PDZ domain DUF726 PF05277.7 EWM25086.1 - 5.1e-76 255.7 2.1 1.9e-64 217.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF726) Abhydrolase_5 PF12695.2 EWM25086.1 - 0.022 14.5 0.1 0.058 13.1 0.1 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Tmemb_14 PF03647.8 EWM25087.1 - 3.8e-15 56.0 5.8 4.5e-15 55.8 4.0 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF2416 PF10315.4 EWM25087.1 - 0.084 13.1 0.9 0.1 12.8 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2416) MFS_1 PF07690.11 EWM25087.1 - 0.18 10.5 4.6 0.2 10.3 3.2 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily UCH PF00443.24 EWM25089.1 - 6.7e-09 35.2 0.0 6.1e-08 32.1 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C28 PF05408.6 EWM25089.1 - 0.017 14.5 0.0 0.068 12.6 0.0 1.9 2 0 0 2 2 2 0 Foot-and-mouth virus L-proteinase RRN3 PF05327.6 EWM25090.1 - 2.3e-61 207.5 0.0 8.2e-43 146.3 0.0 3.5 2 1 0 2 2 2 2 RNA polymerase I specific transcription initiation factor RRN3 DUF2890 PF11081.3 EWM25090.1 - 2.2 8.2 10.5 4.6 7.2 7.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Thioredox_DsbH PF03190.10 EWM25091.1 - 1.4e-67 226.4 0.0 2.2e-67 225.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 EWM25091.1 - 2.7e-09 36.9 0.0 4.9e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Glyco_hydro_88 PF07470.8 EWM25091.1 - 0.014 14.4 0.2 0.13 11.2 0.0 2.5 3 0 0 3 3 3 0 Glycosyl Hydrolase Family 88 Thioredoxin_2 PF13098.1 EWM25091.1 - 0.015 15.4 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain Macro PF01661.16 EWM25092.1 - 5.2e-37 126.3 0.0 9.4e-37 125.5 0.0 1.4 1 0 0 1 1 1 1 Macro domain V-ATPase_C PF03223.10 EWM25093.1 - 0.18 10.6 0.5 0.25 10.2 0.3 1.1 1 0 0 1 1 1 0 V-ATPase subunit C PAS_4 PF08448.5 EWM25094.1 - 0.056 13.4 0.0 0.24 11.4 0.0 2.1 2 0 0 2 2 2 0 PAS fold eRF1_2 PF03464.10 EWM25096.1 - 3.5e-41 140.6 0.0 6.1e-41 139.8 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EWM25096.1 - 2e-35 121.4 0.2 3.8e-35 120.5 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EWM25096.1 - 3.1e-27 94.7 0.0 5.2e-27 94.0 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 COPI_assoc PF08507.5 EWM25099.1 - 5.2e-07 29.4 7.9 7.8e-07 28.8 5.5 1.2 1 0 0 1 1 1 1 COPI associated protein Mito_carr PF00153.22 EWM25100.1 - 4.9e-44 147.9 7.3 2.4e-17 62.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Acetyltransf_1 PF00583.19 EWM25101.1 - 1.7e-09 37.6 0.0 3.8e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EWM25101.1 - 2.3e-06 27.6 0.0 4.5e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EWM25101.1 - 0.00023 21.3 0.0 0.00094 19.3 0.0 1.9 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EWM25101.1 - 0.0023 18.0 0.0 0.0053 16.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EWM25101.1 - 0.028 14.2 0.1 0.084 12.7 0.0 1.8 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase FR47 PF08445.5 EWM25101.1 - 0.051 13.3 0.0 0.21 11.3 0.0 2.0 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_9 PF13527.1 EWM25101.1 - 0.097 12.5 0.0 0.84 9.4 0.0 2.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EWM25101.1 - 0.1 12.2 0.0 0.44 10.1 0.0 2.0 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Abhydrolase_3 PF07859.8 EWM25102.1 - 1.1e-16 61.0 0.2 2.5e-16 59.8 0.1 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.23 EWM25102.1 - 5.8e-14 51.6 0.0 1.1e-13 50.8 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EWM25102.1 - 3.2e-06 26.9 0.1 4.6e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family RRF PF01765.14 EWM25103.1 - 1.6e-63 213.0 0.1 1.6e-63 213.0 0.1 1.5 2 0 0 2 2 2 1 Ribosome recycling factor OB_NTP_bind PF07717.11 EWM25104.1 - 2.1e-29 101.6 0.1 6.1e-29 100.1 0.1 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EWM25104.1 - 2e-24 85.5 0.0 2e-24 85.5 0.0 2.9 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EWM25104.1 - 3.1e-12 46.1 0.0 9.3e-12 44.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EWM25104.1 - 2.9e-08 33.4 0.1 1.6e-07 30.9 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EWM25104.1 - 1.2e-05 25.4 0.0 4.1e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.9 EWM25104.1 - 0.0015 18.3 0.4 0.0099 15.6 0.1 2.2 2 0 0 2 2 2 1 Flavivirus DEAD domain AAA_19 PF13245.1 EWM25104.1 - 0.042 13.6 0.1 0.73 9.6 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain FmdE PF02663.9 EWM25104.1 - 0.3 10.9 4.8 0.83 9.5 0.0 3.2 3 0 0 3 3 3 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Calreticulin PF00262.13 EWM25105.1 - 2.8e-114 381.6 2.4 2.8e-114 381.6 1.7 2.1 2 0 0 2 2 2 2 Calreticulin family Pex14_N PF04695.8 EWM25106.1 - 5.7e-08 32.9 0.0 7.3e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1335 PF07056.6 EWM25106.1 - 0.02 14.6 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1335) Mic1 PF07035.7 EWM25106.1 - 0.093 12.0 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Colon cancer-associated protein Mic1-like NIF PF03031.13 EWM25107.1 - 1.6e-17 63.5 0.0 2.2e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase SNase PF00565.12 EWM25108.1 - 3.6e-61 204.1 0.0 1.2e-14 54.5 0.3 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 EWM25108.1 - 1.7e-17 63.4 0.0 3e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Tudor domain HLH PF00010.21 EWM25109.1 - 1.2e-10 40.8 3.8 2.3e-10 39.9 2.6 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS PF00989.19 EWM25109.1 - 1.8e-07 30.9 0.0 3.7e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 EWM25109.1 - 2.1e-07 30.9 0.0 8.6e-07 28.9 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 EWM25109.1 - 6.4e-07 29.6 0.0 1.5e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.1 EWM25109.1 - 0.00011 21.9 0.0 0.00029 20.5 0.0 1.8 1 0 0 1 1 1 1 PAS domain Ribosomal_60s PF00428.14 EWM25109.1 - 0.0056 17.0 16.4 0.022 15.1 4.5 2.5 2 0 0 2 2 2 2 60s Acidic ribosomal protein PAS_11 PF14598.1 EWM25109.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 PAS domain Sigma70_ner PF04546.8 EWM25109.1 - 0.022 14.3 4.7 0.035 13.7 3.3 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF3138 PF11336.3 EWM25109.1 - 0.17 10.0 3.2 0.27 9.3 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Ank_2 PF12796.2 EWM25111.1 - 8.8e-27 93.2 0.0 3.3e-16 59.4 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EWM25111.1 - 2e-23 80.9 6.0 2e-05 24.1 0.0 6.2 5 1 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 EWM25111.1 - 5e-21 74.2 1.7 1.4e-05 25.1 0.0 5.6 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EWM25111.1 - 7.1e-21 74.1 0.1 9.5e-09 35.5 0.0 4.4 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM25111.1 - 1.3e-18 65.1 0.6 0.00044 20.2 0.0 5.8 5 1 0 5 5 5 4 Ankyrin repeat DUF2254 PF10011.4 EWM25111.1 - 0.066 11.6 0.1 0.1 11.0 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) UbiA PF01040.13 EWM25111.1 - 0.26 10.4 7.9 0.018 14.2 1.3 1.9 2 1 0 2 2 2 0 UbiA prenyltransferase family adh_short_C2 PF13561.1 EWM25112.1 - 1.2e-24 87.4 0.0 1.5e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EWM25112.1 - 6e-11 42.5 1.0 1.9e-10 40.9 0.7 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EWM25112.1 - 0.023 14.3 0.3 1.8 8.2 0.0 2.2 2 0 0 2 2 2 0 KR domain Pex14_N PF04695.8 EWM25114.1 - 4.1e-11 43.0 0.0 4.1e-11 43.0 0.0 2.9 3 1 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Nnf1 PF03980.9 EWM25115.1 - 0.051 13.5 2.9 0.098 12.6 2.0 1.7 1 1 0 1 1 1 0 Nnf1 DUF3997 PF13162.1 EWM25115.1 - 0.082 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3997) WD40 PF00400.27 EWM25117.1 - 0.0013 18.4 0.0 6.7 6.7 0.0 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat PQQ_2 PF13360.1 EWM25117.1 - 0.089 12.2 1.3 13 5.1 0.0 2.8 1 1 0 2 2 2 0 PQQ-like domain PQQ PF01011.16 EWM25117.1 - 0.1 12.1 0.0 0.76 9.4 0.0 2.5 2 0 0 2 2 2 0 PQQ enzyme repeat LTD PF00932.14 EWM25118.1 - 4.8e-09 36.3 0.0 9.3e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Lamin Tail Domain ThiF PF00899.16 EWM25119.1 - 6.2e-44 149.1 0.1 1.1e-42 145.0 0.0 2.2 2 0 0 2 2 2 1 ThiF family MoeZ_MoeB PF05237.8 EWM25119.1 - 6.3e-27 93.0 0.0 1.2e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 EWM25119.1 - 5.7e-10 39.5 0.0 1.6e-09 38.0 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain WD40 PF00400.27 EWM25120.1 - 1.5e-66 218.0 5.0 1.4e-11 43.8 0.0 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EWM25120.1 - 6.4e-06 26.0 0.0 0.77 9.4 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Me-amine-dh_H PF06433.6 EWM25120.1 - 0.007 15.0 0.0 0.013 14.1 0.0 1.5 1 0 0 1 1 1 1 Methylamine dehydrogenase heavy chain (MADH) PD40 PF07676.7 EWM25120.1 - 0.0074 15.9 0.0 16 5.2 0.0 3.9 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Nup160 PF11715.3 EWM25120.1 - 0.0089 14.2 2.4 0.11 10.5 0.6 2.6 2 2 0 2 2 2 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EWM25120.1 - 0.026 12.8 0.1 0.062 11.5 0.0 1.6 2 0 0 2 2 2 0 Cytochrome D1 heme domain DUF3312 PF11768.3 EWM25120.1 - 0.03 12.5 0.0 2.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Gly_transf_sug PF04488.10 EWM25121.1 - 0.0002 21.6 0.0 0.0018 18.6 0.0 2.5 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Sulfotransfer_1 PF00685.22 EWM25121.1 - 0.0011 18.2 0.0 0.0021 17.3 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase domain MRG PF05712.8 EWM25123.1 - 7.6e-15 54.3 0.0 4e-13 48.7 0.0 2.7 2 1 0 2 2 2 1 MRG APG6 PF04111.7 EWM25124.1 - 2.7e-57 194.2 0.0 3.4e-57 193.8 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg6 DUF3419 PF11899.3 EWM25125.1 - 1.9e-76 257.2 0.3 2.8e-76 256.7 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_11 PF08241.7 EWM25125.1 - 1.1e-08 35.4 0.0 9.1e-08 32.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EWM25125.1 - 1.4e-08 34.1 0.0 2.8e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 EWM25125.1 - 5.5e-08 32.7 0.0 1.5e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM25125.1 - 6.8e-08 32.8 0.0 8.3e-07 29.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM25125.1 - 7.4e-07 28.8 0.0 5.9e-06 25.9 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM25125.1 - 2.8e-05 24.4 0.0 0.00038 20.7 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM25125.1 - 4.2e-05 24.0 0.0 0.00022 21.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM25125.1 - 0.0077 16.2 0.0 0.043 13.8 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain DUF2023 PF09633.5 EWM25125.1 - 0.027 14.4 0.0 0.062 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2023) Filament PF00038.16 EWM25126.1 - 0.0099 15.3 18.0 0.033 13.6 6.0 2.5 2 0 0 2 2 2 2 Intermediate filament protein IncA PF04156.9 EWM25126.1 - 0.054 13.0 20.4 0.081 12.5 5.3 2.5 2 0 0 2 2 2 0 IncA protein Bacillus_HBL PF05791.6 EWM25126.1 - 0.32 10.3 8.5 2.3 7.5 2.1 2.5 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) ATG16 PF08614.6 EWM25126.1 - 2 8.2 24.2 0.23 11.2 4.2 2.7 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 EWM25126.1 - 4.6 6.3 7.2 3 6.9 0.2 2.9 3 0 0 3 3 3 0 Reovirus sigma C capsid protein ERM PF00769.14 EWM25126.1 - 5 6.5 27.1 1 8.8 9.7 2.6 2 0 0 2 2 2 0 Ezrin/radixin/moesin family VDE PF07137.6 EWM25127.1 - 5.9e-20 71.9 0.0 1.2e-19 70.9 0.0 1.5 1 0 0 1 1 1 1 Violaxanthin de-epoxidase (VDE) Lipocalin PF00061.18 EWM25127.1 - 0.0066 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_2 PF08212.7 EWM25127.1 - 0.032 14.0 0.0 1.2 8.9 0.0 2.8 3 0 0 3 3 3 0 Lipocalin-like domain NTF2 PF02136.15 EWM25128.1 - 1.6e-17 63.9 0.0 2.6e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain PGA2 PF07543.7 EWM25128.1 - 0.29 10.9 3.9 0.65 9.7 2.7 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 PsbP PF01789.11 EWM25129.1 - 0.00039 19.9 0.3 0.00082 18.8 0.2 1.6 1 1 0 1 1 1 1 PsbP DUF726 PF05277.7 EWM25129.1 - 0.14 11.0 1.8 0.23 10.3 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF726) PHD_2 PF13831.1 EWM25130.1 - 8.7e-10 37.7 0.6 8.7e-10 37.7 0.4 3.4 3 0 0 3 3 3 1 PHD-finger PHD PF00628.24 EWM25130.1 - 1.9e-07 30.6 7.9 1.9e-07 30.6 5.5 3.8 4 1 0 4 4 4 1 PHD-finger zf-HC5HC2H PF13771.1 EWM25130.1 - 0.0017 18.4 1.8 0.0017 18.4 1.3 3.6 3 0 0 3 3 3 1 PHD-like zinc-binding domain GCC2_GCC3 PF07699.8 EWM25130.1 - 2.2 7.9 7.2 0.39 10.3 1.8 2.2 2 0 0 2 2 2 0 GCC2 and GCC3 FYVE_2 PF02318.11 EWM25130.1 - 9.2 6.1 12.1 0.52 10.2 3.3 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger Na_H_Exchanger PF00999.16 EWM25131.1 - 2.5e-37 128.3 24.8 3.3e-37 127.9 17.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family APC_crr PF05923.7 EWM25131.1 - 0.052 13.1 0.5 0.13 11.8 0.4 1.7 1 0 0 1 1 1 0 APC cysteine-rich region Adeno_E3_CR2 PF02439.10 EWM25131.1 - 4.3 6.9 6.5 1.1 8.8 0.4 2.7 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 CAF1A PF12253.3 EWM25132.1 - 5.4e-16 58.4 15.7 5.4e-16 58.4 10.9 2.9 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A TAF4 PF05236.9 EWM25132.1 - 0.0002 20.7 17.7 0.0004 19.7 12.3 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Neur_chan_memb PF02932.11 EWM25132.1 - 0.7 9.7 3.8 5.6 6.7 0.5 2.8 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region SAPS PF04499.10 EWM25132.1 - 6.2 5.3 10.4 12 4.3 7.2 1.5 1 1 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1015 PF06245.6 EWM25133.1 - 2.9e-126 421.3 0.0 3.3e-126 421.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1015) Ribosomal_S8e PF01201.17 EWM25134.1 - 2e-49 167.0 1.6 2.5e-49 166.8 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e ADH_zinc_N PF00107.21 EWM25135.1 - 0.001 18.5 0.4 0.0022 17.5 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EWM25135.1 - 0.012 15.3 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain adh_short PF00106.20 EWM25136.1 - 4.1e-18 65.8 0.3 4.1e-18 65.8 0.2 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EWM25136.1 - 1.9e-11 44.2 0.0 3.3e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EWM25136.1 - 2.3e-10 40.1 0.0 1.2e-09 37.7 0.0 1.9 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EWM25136.1 - 7e-06 26.1 0.3 2.5e-05 24.3 0.0 2.0 2 1 0 2 2 2 1 NADH(P)-binding KR PF08659.5 EWM25136.1 - 4.5e-05 23.1 0.1 9.4e-05 22.1 0.1 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EWM25136.1 - 0.022 14.1 0.0 0.053 12.9 0.0 1.6 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family F-actin_cap_A PF01267.12 EWM25137.1 - 7.2e-43 146.5 0.1 1.6e-36 125.8 0.1 2.0 1 1 1 2 2 2 2 F-actin capping protein alpha subunit Octopine_DH PF02317.12 EWM25138.1 - 2.7e-24 85.5 0.0 4.2e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain NAD_Gly3P_dh_N PF01210.18 EWM25138.1 - 0.00064 19.4 0.1 0.0013 18.4 0.1 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PaO PF08417.7 EWM25140.1 - 4.4e-17 61.7 0.9 5.9e-16 58.1 0.6 2.3 1 1 0 1 1 1 1 Pheophorbide a oxygenase Rieske PF00355.21 EWM25140.1 - 2.6e-16 58.9 0.0 4.7e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 EWM25140.1 - 1.5e-05 24.6 0.0 3.9e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain SSF PF00474.12 EWM25140.1 - 0.24 10.0 0.0 0.33 9.5 0.0 1.1 1 0 0 1 1 1 0 Sodium:solute symporter family LRR_6 PF13516.1 EWM25141.1 - 2e-18 64.3 5.4 0.11 12.5 0.0 7.3 6 0 0 6 6 6 5 Leucine Rich repeat LRR_4 PF12799.2 EWM25141.1 - 8.7e-07 28.4 0.5 0.12 12.0 0.0 4.6 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EWM25141.1 - 0.0014 18.4 7.1 31 5.3 0.0 6.6 6 0 0 6 6 6 1 Leucine rich repeat LRR_8 PF13855.1 EWM25141.1 - 0.029 14.1 6.2 3.2 7.5 0.6 5.0 3 2 3 6 6 6 0 Leucine rich repeat ATP-synt_ab PF00006.20 EWM25142.1 - 6e-62 208.9 0.0 1e-61 208.2 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EWM25142.1 - 8.6e-25 87.4 0.6 2e-24 86.2 0.4 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EWM25142.1 - 1.6e-20 73.0 2.1 3.2e-20 72.1 1.5 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain KaiC PF06745.8 EWM25142.1 - 0.034 13.2 1.4 0.079 12.0 1.0 1.6 1 0 0 1 1 1 0 KaiC SeleniumBinding PF11524.3 EWM25142.1 - 0.068 13.3 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Selenium binding protein Syntaxin_2 PF14523.1 EWM25142.1 - 0.075 13.0 0.2 15 5.6 0.0 3.1 3 0 0 3 3 3 0 Syntaxin-like protein AAA_22 PF13401.1 EWM25142.1 - 0.1 12.7 0.0 0.38 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain Sulfotransfer_1 PF00685.22 EWM25143.1 - 3.8e-10 39.4 0.2 2.9e-09 36.5 0.1 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 EWM25143.1 - 1.6e-05 25.8 4.3 1.6e-05 25.8 3.0 2.7 2 1 0 2 2 2 1 Sulfotransferase family FKBP_C PF00254.23 EWM25144.1 - 1.9e-30 104.7 0.0 2.7e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Vps35 PF03635.12 EWM25145.1 - 2.2e-244 813.1 0.0 2.6e-244 812.9 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Tenui_NCP PF04876.7 EWM25145.1 - 0.029 13.9 0.0 0.068 12.7 0.0 1.6 1 0 0 1 1 1 0 Tenuivirus major non-capsid protein UCH PF00443.24 EWM25148.1 - 7.9e-54 182.5 0.0 1.1e-53 182.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EWM25148.1 - 7.8e-16 58.3 0.0 1.4e-14 54.2 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EWM25148.1 - 2.7e-05 23.4 0.0 5.6e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family UIM PF02809.15 EWM25148.1 - 0.02 14.4 6.0 0.02 14.4 4.1 2.5 3 0 0 3 3 3 0 Ubiquitin interaction motif Ubiquitin_2 PF14560.1 EWM25148.1 - 0.025 14.8 0.0 0.24 11.6 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain Peptidase_C98 PF15499.1 EWM25148.1 - 0.19 10.9 0.0 1.2 8.3 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase RVT_1 PF00078.22 EWM25149.1 - 0.0087 15.4 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MutS_V PF00488.16 EWM25150.1 - 3e-85 285.3 0.0 4.3e-85 284.8 0.0 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EWM25150.1 - 4.1e-39 134.5 0.7 6.2e-39 133.9 0.5 1.3 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EWM25150.1 - 6.3e-30 103.5 0.0 1.2e-29 102.6 0.0 1.4 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.13 EWM25150.1 - 7.2e-14 51.7 1.4 7.4e-14 51.7 0.1 1.7 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.12 EWM25150.1 - 1.5e-08 34.7 0.0 7.6e-08 32.5 0.0 2.2 2 0 0 2 2 2 1 MutS domain II 53-BP1_Tudor PF09038.5 EWM25150.1 - 0.036 13.8 0.0 0.087 12.6 0.0 1.7 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor DZR PF12773.2 EWM25151.1 - 0.0032 17.2 3.3 0.013 15.2 2.3 2.1 1 1 0 1 1 1 1 Double zinc ribbon Gly-zipper_OmpA PF13436.1 EWM25151.1 - 2.3 7.9 11.0 4.7 6.9 7.6 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain PEPcase PF00311.12 EWM25152.1 - 3.4e-265 881.8 0.2 4.3e-265 881.4 0.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.1 EWM25152.1 - 6e-06 24.8 0.0 2.3e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Phosphoenolpyruvate carboxylase Mt_ATP-synt_B PF05405.9 EWM25153.1 - 1.1e-13 50.9 1.8 1.8e-13 50.2 1.2 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) ATP-synt_B PF00430.13 EWM25153.1 - 0.0084 15.9 0.1 0.0084 15.9 0.1 1.9 2 0 0 2 2 2 1 ATP synthase B/B' CF(0) DUF885 PF05960.6 EWM25153.1 - 0.29 10.2 4.3 0.53 9.3 2.9 1.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF885) GRAM PF02893.15 EWM25155.1 - 2.4e-10 39.7 0.1 4e-10 39.0 0.1 1.4 1 0 0 1 1 1 1 GRAM domain Lipase_3 PF01764.20 EWM25157.1 - 8.2e-33 112.9 0.0 1.1e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 EWM25157.1 - 8.3e-05 22.0 0.0 0.00016 21.1 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.2 EWM25157.1 - 0.0027 17.6 1.2 0.0032 17.3 0.8 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 EWM25157.1 - 0.0038 16.9 0.0 0.012 15.3 0.0 1.7 1 1 1 2 2 2 1 Cutinase PGAP1 PF07819.8 EWM25157.1 - 0.0066 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 EWM25157.1 - 0.014 15.6 0.2 0.019 15.1 0.2 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.2 EWM25157.1 - 0.022 14.4 0.2 0.045 13.4 0.2 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Mesothelin PF06060.7 EWM25159.1 - 0.045 11.8 1.5 0.061 11.3 1.0 1.1 1 0 0 1 1 1 0 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) TMEM173 PF15009.1 EWM25159.1 - 0.34 9.6 1.1 0.52 9.0 0.8 1.2 1 0 0 1 1 1 0 Transmembrane protein 173 Pkinase PF00069.20 EWM25160.1 - 1.5e-51 175.0 0.0 1.9e-51 174.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM25160.1 - 2.3e-32 112.1 0.0 3.1e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EWM25160.1 - 0.007 16.1 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EWM25160.1 - 0.0076 15.2 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EWM25160.1 - 0.016 14.2 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-Mss51 PF13824.1 EWM25160.1 - 3.9 7.3 8.1 8 6.4 0.0 3.5 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 RrnaAD PF00398.15 EWM25161.1 - 4.7e-05 22.5 0.0 7.1e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.2 EWM25161.1 - 0.014 16.0 0.0 0.025 15.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EWM25161.1 - 0.017 14.6 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) bZIP_1 PF00170.16 EWM25162.1 - 5.7e-08 32.5 10.1 5.7e-08 32.5 7.0 2.4 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EWM25162.1 - 0.0086 15.8 11.0 0.0086 15.8 7.6 2.2 2 0 0 2 2 2 1 Basic region leucine zipper Tsg PF04668.7 EWM25162.1 - 0.058 13.5 0.3 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 Twisted gastrulation (Tsg) protein conserved region ADIP PF11559.3 EWM25162.1 - 0.29 11.0 0.1 0.29 11.0 0.1 2.6 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding DUF4618 PF15397.1 EWM25162.1 - 0.3 10.3 7.4 0.18 11.1 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Metal_resist PF13801.1 EWM25162.1 - 0.98 9.4 0.0 0.98 9.4 0.0 2.8 2 1 1 3 3 3 0 Heavy-metal resistance Histone_HNS PF00816.16 EWM25162.1 - 1.9 9.0 7.7 12 6.4 1.4 2.4 2 0 0 2 2 2 0 H-NS histone family Ion_trans PF00520.26 EWM25163.1 - 3.3e-06 26.4 9.1 1.4e-05 24.4 3.0 2.5 2 1 0 2 2 2 1 Ion transport protein Pkinase PF00069.20 EWM25166.1 - 1.2e-53 181.9 0.0 2.5e-53 180.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM25166.1 - 1.3e-24 86.6 0.0 1.8e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EWM25166.1 - 0.00068 19.4 0.4 0.0018 18.0 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EWM25166.1 - 0.011 15.3 0.1 0.02 14.4 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Cyanate_lyase PF02560.9 EWM25168.1 - 4e-11 42.2 0.1 1e-10 40.9 0.0 1.6 2 0 0 2 2 2 1 Cyanate lyase C-terminal domain HTH_24 PF13412.1 EWM25168.1 - 0.025 13.9 0.0 0.052 12.9 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_3 PF01381.17 EWM25168.1 - 0.054 13.3 0.0 0.091 12.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix Rrf2 PF02082.15 EWM25168.1 - 0.088 12.9 0.1 0.13 12.3 0.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator DUF2774 PF11242.3 EWM25168.1 - 0.16 12.0 0.5 0.66 9.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) Herpes_US9 PF06072.6 EWM25170.1 - 0.015 15.1 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Peptidase_S8 PF00082.17 EWM25172.1 - 5.4e-37 127.4 0.0 9e-37 126.7 0.0 1.3 1 0 0 1 1 1 1 Subtilase family BTK PF00779.14 EWM25177.1 - 2.4e-07 30.2 5.5 8.1e-05 22.1 1.5 2.3 2 0 0 2 2 2 2 BTK motif CHORD PF04968.7 EWM25177.1 - 0.0077 16.4 4.8 0.02 15.1 0.3 2.3 2 0 0 2 2 2 1 CHORD RPAP3_C PF13877.1 EWM25179.1 - 0.0036 17.2 0.0 2.4 8.1 0.0 3.3 2 1 1 3 3 3 2 Potential Monad-binding region of RPAP3 Ion_trans PF00520.26 EWM25180.1 - 4.9e-10 38.9 13.1 6.5e-10 38.5 6.4 2.6 2 1 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 EWM25180.1 - 1.4e-09 37.5 0.7 1.4e-09 37.5 0.5 2.3 2 1 0 2 2 2 1 Ion channel E1-E2_ATPase PF00122.15 EWM25181.1 - 3.4e-63 212.7 0.1 3.4e-63 212.7 0.1 1.7 1 1 1 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.21 EWM25181.1 - 2.9e-12 45.8 0.0 5.7e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EWM25181.1 - 0.019 14.9 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Flavokinase PF01687.12 EWM25182.1 - 5.3e-31 107.1 0.0 7.4e-31 106.6 0.0 1.2 1 0 0 1 1 1 1 Riboflavin kinase Methyltransf_11 PF08241.7 EWM25182.1 - 4e-05 24.0 0.0 8.8e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM25182.1 - 0.0014 18.1 0.0 0.0021 17.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM25182.1 - 0.0049 16.6 0.0 0.0075 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM25182.1 - 0.0071 16.9 0.0 0.012 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM25182.1 - 0.023 14.7 0.0 0.18 11.8 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EWM25182.1 - 0.055 13.9 0.0 0.082 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EWM25182.1 - 0.16 11.0 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Flavokinase PF01687.12 EWM25183.1 - 5.3e-31 107.1 0.0 7.4e-31 106.6 0.0 1.2 1 0 0 1 1 1 1 Riboflavin kinase Methyltransf_11 PF08241.7 EWM25183.1 - 4e-05 24.0 0.0 8.8e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM25183.1 - 0.0014 18.1 0.0 0.0021 17.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM25183.1 - 0.0049 16.6 0.0 0.0075 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM25183.1 - 0.0071 16.9 0.0 0.012 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM25183.1 - 0.023 14.7 0.0 0.18 11.8 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EWM25183.1 - 0.055 13.9 0.0 0.082 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EWM25183.1 - 0.16 11.0 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Cation_ATPase_C PF00689.16 EWM25184.1 - 0.0024 17.4 0.3 0.0037 16.8 0.2 1.3 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Zn_clus PF00172.13 EWM25186.1 - 8.4e-07 28.8 8.6 1.7e-06 27.7 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 EWM25188.1 - 2.4e-08 33.7 9.0 5e-08 32.7 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Inhibitor_I68 PF10468.4 EWM25188.1 - 0.45 10.7 5.7 0.42 10.8 0.1 2.6 1 1 1 2 2 2 0 Carboxypeptidase inhibitor I68 Zn_clus PF00172.13 EWM25191.1 - 3.6e-07 29.9 15.9 7.8e-07 28.9 11.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF755 PF05501.6 EWM25191.1 - 1.7 8.7 12.1 0.029 14.4 3.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Cation_ATPase_C PF00689.16 EWM25192.1 - 4.3e-15 55.7 0.0 5.2e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Pkinase PF00069.20 EWM25194.1 - 2.9e-62 210.1 0.0 3.2e-62 210.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM25194.1 - 1.6e-33 115.8 0.0 2.4e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EWM25194.1 - 0.00082 19.1 0.6 0.0017 18.1 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EWM25194.1 - 0.043 12.7 0.0 0.068 12.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like PAP1 PF08601.5 EWM25196.1 - 0.85 9.2 5.5 0.68 9.5 3.1 1.3 1 1 0 1 1 1 0 Transcription factor PAP1 Histone PF00125.19 EWM25200.1 - 1.4e-32 111.5 0.3 2.5e-32 110.8 0.2 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EWM25200.1 - 6.1e-05 23.1 0.0 0.00012 22.1 0.0 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EWM25200.1 - 0.077 13.0 0.2 0.53 10.3 0.0 2.2 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TIL PF01826.12 EWM25201.1 - 2.1e-05 24.5 13.9 3.4e-05 23.8 9.7 1.3 1 0 0 1 1 1 1 Trypsin Inhibitor like cysteine rich domain TIL PF01826.12 EWM25202.1 - 1.3e-05 25.2 13.9 2.2e-05 24.4 9.7 1.4 1 0 0 1 1 1 1 Trypsin Inhibitor like cysteine rich domain FtsJ PF01728.14 EWM25206.1 - 9.7e-11 41.9 0.0 1.4e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 EWM25206.1 - 0.032 13.9 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EWM25207.1 - 4.3e-06 26.8 0.0 7.1e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase SSF PF00474.12 EWM25208.1 - 1.1e-18 67.0 30.0 1.9e-18 66.3 20.8 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family HhH-GPD PF00730.20 EWM25209.1 - 9.3e-14 51.6 0.0 2.6e-13 50.1 0.0 1.8 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein DUF4604 PF15377.1 EWM25209.1 - 0.012 15.8 13.8 0.018 15.2 9.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) OGG_N PF07934.7 EWM25209.1 - 0.027 14.4 0.2 0.1 12.6 0.0 1.9 2 0 0 2 2 2 0 8-oxoguanine DNA glycosylase, N-terminal domain HHH PF00633.18 EWM25209.1 - 0.036 13.7 0.3 0.36 10.6 0.0 2.7 2 1 0 2 2 2 0 Helix-hairpin-helix motif UPF0542 PF15086.1 EWM25209.1 - 1.8 8.3 7.6 0.23 11.2 1.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 SP_C-Propep PF08999.5 EWM25210.1 - 0.023 14.1 3.2 0.025 14.0 2.2 1.2 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide ODV-E18 PF10717.4 EWM25210.1 - 0.082 12.3 0.3 0.12 11.8 0.2 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Sec62 PF03839.11 EWM25210.1 - 0.083 12.2 0.4 0.11 11.9 0.3 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 YIF1 PF03878.10 EWM25210.1 - 0.089 11.9 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 YIF1 Shisa PF13908.1 EWM25210.1 - 0.16 12.1 0.4 0.18 11.9 0.3 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF3311 PF11755.3 EWM25211.1 - 0.38 10.3 4.3 8.1 6.0 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3311) ABC_membrane PF00664.18 EWM25213.1 - 1.5e-13 50.7 0.3 1.8e-13 50.5 0.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region LRR19-TM PF15176.1 EWM25213.1 - 0.16 11.6 0.1 0.27 10.9 0.1 1.3 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain HPP PF04982.8 EWM25213.1 - 1.7 8.5 9.7 2.4 8.0 1.1 2.9 1 1 1 2 2 2 0 HPP family ABC_tran PF00005.22 EWM25214.1 - 2.6e-08 34.2 0.0 3.3e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 ABC transporter FHA PF00498.21 EWM25215.1 - 3e-12 46.4 0.0 4.6e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 FHA domain Nucleo_P87 PF07267.6 EWM25216.1 - 0.013 14.2 10.3 0.018 13.7 7.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NAM-associated PF14303.1 EWM25216.1 - 0.014 15.7 8.2 0.03 14.6 5.7 1.5 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain FimP PF09766.4 EWM25216.1 - 0.019 14.0 6.9 0.072 12.1 5.4 1.4 2 0 0 2 2 1 0 Fms-interacting protein Ribosomal_60s PF00428.14 EWM25216.1 - 0.061 13.7 11.1 0.16 12.3 7.7 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein PBP1_TM PF14812.1 EWM25216.1 - 0.084 13.1 8.7 0.17 12.2 6.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal VID27 PF08553.5 EWM25216.1 - 0.11 10.7 12.3 0.14 10.3 8.5 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein RRN3 PF05327.6 EWM25216.1 - 0.11 10.6 3.1 0.2 9.7 2.1 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Ycf1 PF05758.7 EWM25216.1 - 0.12 10.0 3.0 0.13 9.9 2.1 1.1 1 0 0 1 1 1 0 Ycf1 Myc_N PF01056.13 EWM25216.1 - 0.14 11.2 11.6 0.24 10.5 8.1 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Sigma70_ner PF04546.8 EWM25216.1 - 0.15 11.6 13.7 0.48 10.0 7.9 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Folate_carrier PF01770.13 EWM25216.1 - 0.18 10.2 0.6 0.29 9.6 0.4 1.2 1 0 0 1 1 1 0 Reduced folate carrier Spore_coat_CotO PF14153.1 EWM25216.1 - 0.24 10.8 14.3 0.4 10.0 9.9 1.3 1 0 0 1 1 1 0 Spore coat protein CotO PPP4R2 PF09184.6 EWM25216.1 - 0.25 10.8 18.5 0.36 10.3 12.8 1.2 1 0 0 1 1 1 0 PPP4R2 DUF913 PF06025.7 EWM25216.1 - 0.27 9.9 2.0 0.44 9.2 1.4 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Daxx PF03344.10 EWM25216.1 - 0.31 9.4 17.3 0.49 8.8 12.0 1.2 1 0 0 1 1 1 0 Daxx Family DDHD PF02862.12 EWM25216.1 - 0.32 10.7 8.5 0.57 9.9 5.9 1.4 1 0 0 1 1 1 0 DDHD domain Prothymosin PF03247.9 EWM25216.1 - 0.41 10.8 26.4 0.88 9.7 18.3 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family Vfa1 PF08432.5 EWM25216.1 - 0.49 10.3 10.2 0.81 9.6 7.1 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TRAP_alpha PF03896.11 EWM25216.1 - 0.61 9.0 10.8 0.94 8.4 7.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Merozoite_SPAM PF07133.6 EWM25216.1 - 0.67 9.8 21.8 1.1 9.1 15.1 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) RNA_pol_3_Rpc31 PF11705.3 EWM25216.1 - 0.85 9.5 15.8 0.7 9.7 9.9 1.6 2 0 0 2 2 1 0 DNA-directed RNA polymerase III subunit Rpc31 CENP-B_dimeris PF09026.5 EWM25216.1 - 0.9 9.8 14.4 0.19 11.9 7.3 1.9 2 0 0 2 2 1 0 Centromere protein B dimerisation domain CDC45 PF02724.9 EWM25216.1 - 1.1 7.1 12.3 1.5 6.7 8.5 1.1 1 0 0 1 1 1 0 CDC45-like protein SMN PF06003.7 EWM25216.1 - 1.3 8.0 6.0 2 7.4 4.1 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DUF1510 PF07423.6 EWM25216.1 - 1.3 8.3 15.2 2 7.7 10.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Tim54 PF11711.3 EWM25216.1 - 1.3 7.5 9.6 2.3 6.7 6.7 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 HSP90 PF00183.13 EWM25216.1 - 1.6 7.0 14.9 2.2 6.5 10.3 1.1 1 0 0 1 1 1 0 Hsp90 protein NOA36 PF06524.7 EWM25216.1 - 1.6 7.8 7.4 2.3 7.3 5.2 1.1 1 0 0 1 1 1 0 NOA36 protein RNase_H2-Ydr279 PF09468.5 EWM25216.1 - 2.6 7.1 7.3 4.2 6.4 5.1 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) SprA-related PF12118.3 EWM25216.1 - 2.6 7.2 16.3 4.3 6.5 11.3 1.3 1 0 0 1 1 1 0 SprA-related family Nucleoplasmin PF03066.10 EWM25216.1 - 2.7 7.5 20.9 4.3 6.8 14.5 1.3 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 EWM25216.1 - 3.2 5.5 17.7 5 4.9 12.2 1.2 1 0 0 1 1 1 0 Nop14-like family HAUS6_N PF14661.1 EWM25216.1 - 3.3 6.9 11.1 5.8 6.1 7.7 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Eapp_C PF10238.4 EWM25216.1 - 3.3 7.5 7.5 5.8 6.8 5.2 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein LMBR1 PF04791.11 EWM25216.1 - 4.7 5.6 5.0 2.2 6.7 2.2 1.3 2 0 0 2 2 2 0 LMBR1-like membrane protein Prog_receptor PF02161.10 EWM25216.1 - 8 5.1 10.4 14 4.3 7.2 1.3 1 0 0 1 1 1 0 Progesterone receptor TFIIF_alpha PF05793.7 EWM25216.1 - 8.6 4.6 19.6 12 4.0 13.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) p450 PF00067.17 EWM25219.1 - 0.0014 17.2 0.0 0.0017 16.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3326 PF11805.3 EWM25222.1 - 8.5e-118 392.9 0.1 1.1e-117 392.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3326) DUF4066 PF13278.1 EWM25222.1 - 6.2e-09 35.3 3.0 5.4e-07 29.0 1.8 3.2 2 1 0 2 2 2 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EWM25222.1 - 0.0023 17.4 0.0 0.0044 16.4 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family ThiF PF00899.16 EWM25223.1 - 2e-37 128.0 0.2 3.3e-37 127.3 0.2 1.4 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 EWM25223.1 - 1.5e-28 98.1 0.3 3.3e-28 97.0 0.2 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UAE_UbL PF14732.1 EWM25223.1 - 2.6e-17 62.7 0.0 4.8e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.4 EWM25223.1 - 1.8e-12 46.3 0.0 3.9e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.1 EWM25223.1 - 0.002 18.3 0.1 0.01 16.0 0.1 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EWM25223.1 - 0.0055 16.8 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EWM25223.1 - 0.065 13.6 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Plasmod_dom_1 PF09715.5 EWM25223.1 - 0.15 11.9 0.1 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Plasmodium protein of unknown function (Plasmod_dom_1) DUF914 PF06027.7 EWM25227.1 - 1.3e-05 24.2 2.4 1.3e-05 24.2 1.7 1.5 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EWM25227.1 - 0.00056 19.9 4.4 0.00056 19.9 3.0 3.1 2 2 1 3 3 3 1 EamA-like transporter family EmrE PF13536.1 EWM25227.1 - 0.0012 19.0 5.9 0.0012 19.0 4.1 3.1 2 2 0 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 EWM25227.1 - 0.005 16.4 12.6 0.029 14.0 2.0 3.0 2 2 0 2 2 2 2 Triose-phosphate Transporter family CRT-like PF08627.5 EWM25227.1 - 0.012 15.5 0.7 0.025 14.4 0.5 1.5 1 0 0 1 1 1 0 CRT-like CENP-B_dimeris PF09026.5 EWM25227.1 - 0.086 13.0 3.6 0.15 12.3 2.5 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain UAA PF08449.6 EWM25227.1 - 3.4 6.5 16.1 31 3.3 11.2 2.3 1 1 0 1 1 1 0 UAA transporter family Ribosomal_60s PF00428.14 EWM25227.1 - 5.7 7.4 11.5 12 6.4 8.0 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein DAGK_acc PF00609.14 EWM25228.1 - 4e-45 153.8 0.0 9.6e-45 152.6 0.0 1.6 2 0 0 2 2 2 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 EWM25228.1 - 2.3e-24 85.2 0.0 3.9e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DAGK_acc PF00609.14 EWM25229.1 - 8e-27 94.3 0.0 2.3e-26 92.8 0.0 1.7 2 0 0 2 2 2 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 EWM25229.1 - 1.7e-24 85.7 0.0 2.7e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Syntaxin-6_N PF09177.6 EWM25231.1 - 0.085 13.2 0.9 0.6 10.5 0.0 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Baculo_PEP_C PF04513.7 EWM25231.1 - 0.095 12.5 1.6 0.17 11.6 0.1 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.8 EWM25231.1 - 0.32 11.4 2.3 8.9 6.7 0.1 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) GBP PF02263.14 EWM25232.1 - 1.9e-32 112.3 0.0 3.7e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 EWM25232.1 - 0.025 14.5 0.0 0.059 13.3 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.1 EWM25232.1 - 0.027 14.3 0.0 0.087 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EWM25232.1 - 0.069 12.5 0.0 0.52 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain MobB PF03205.9 EWM25232.1 - 0.18 11.4 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Pterin_4a PF01329.14 EWM25234.1 - 4.1e-27 93.7 0.0 5.6e-27 93.3 0.0 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Hypoth_Ymh PF09509.5 EWM25235.1 - 0.096 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (Hypoth_ymh) C1_1 PF00130.17 EWM25236.1 - 2.3e-09 36.8 9.7 9e-08 31.7 1.3 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PRT_C PF08372.5 EWM25236.1 - 1.2e-08 34.6 0.2 0.00096 18.6 0.0 2.3 2 0 0 2 2 2 2 Plant phosphoribosyltransferase C-terminal C2 PF00168.25 EWM25236.1 - 8.8e-06 25.4 0.0 2.2e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 C2 domain Pex24p PF06398.6 EWM25236.1 - 1.2e-05 24.3 0.0 0.088 11.5 0.0 2.3 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin C1_3 PF07649.7 EWM25236.1 - 0.017 15.1 6.0 1.1 9.3 2.0 2.4 2 0 0 2 2 2 0 C1-like domain PHD_2 PF13831.1 EWM25236.1 - 0.91 8.8 5.9 1.6 8.1 0.3 2.5 2 0 0 2 2 2 0 PHD-finger DUF4206 PF13901.1 EWM25236.1 - 0.93 9.0 4.6 7.6 6.0 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4206) C1_2 PF03107.11 EWM25236.1 - 2.7 8.2 10.1 0.2 11.8 2.4 2.3 2 0 0 2 2 2 0 C1 domain PRT_C PF08372.5 EWM25237.1 - 9.2e-09 34.9 0.2 0.00082 18.9 0.0 2.3 2 0 0 2 2 2 2 Plant phosphoribosyltransferase C-terminal C1_1 PF00130.17 EWM25237.1 - 4.8e-08 32.6 1.9 7.8e-08 31.9 1.3 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.25 EWM25237.1 - 8.2e-07 28.7 0.0 1.9e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 C2 domain Pex24p PF06398.6 EWM25237.1 - 9.5e-06 24.6 0.0 0.074 11.8 0.0 2.2 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin C1_2 PF03107.11 EWM25237.1 - 0.088 12.9 3.4 0.17 12.0 2.4 1.5 1 0 0 1 1 1 0 C1 domain C1_3 PF07649.7 EWM25237.1 - 0.53 10.3 3.0 0.98 9.5 2.0 1.4 1 0 0 1 1 1 0 C1-like domain ArfGap PF01412.13 EWM25238.1 - 0.1 12.3 0.2 0.1 12.3 0.1 1.4 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf MscS_TM PF12794.2 EWM25239.1 - 0.014 14.0 0.5 0.016 13.8 0.1 1.3 1 1 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF1049 PF06305.6 EWM25239.1 - 7.2 6.1 6.9 1.1 8.7 0.9 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1049) MORN PF02493.15 EWM25240.1 - 1.6e-75 244.5 101.2 4.7e-09 35.4 1.4 16.0 16 0 0 16 16 16 15 MORN repeat PPTA PF01239.17 EWM25241.1 - 0.21 11.0 2.8 2.4 7.6 0.1 2.3 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat FKBP_C PF00254.23 EWM25243.1 - 7.5e-30 102.8 0.1 2.2e-29 101.3 0.0 1.8 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase SNAP PF14938.1 EWM25243.1 - 0.082 12.0 0.7 0.11 11.6 0.5 1.1 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP FKBP_C PF00254.23 EWM25244.1 - 7.5e-30 102.8 0.1 2.2e-29 101.3 0.0 1.8 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase SNAP PF14938.1 EWM25244.1 - 0.082 12.0 0.7 0.11 11.6 0.5 1.1 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP ICA69 PF04629.9 EWM25245.1 - 0.45 10.4 9.2 0.47 10.3 6.4 1.0 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain SIM_C PF06621.7 EWM25245.1 - 0.63 9.5 8.8 1.1 8.8 6.1 1.5 1 1 0 1 1 1 0 Single-minded protein C-terminus HAUS6_N PF14661.1 EWM25245.1 - 4.2 6.6 18.7 4.4 6.5 13.0 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF3512 PF12024.3 EWM25245.1 - 4.2 6.5 10.6 5.1 6.3 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3512) SET PF00856.23 EWM25245.1 - 7 6.9 7.1 7.7 6.8 4.9 1.0 1 0 0 1 1 1 0 SET domain Pro_isomerase PF00160.16 EWM25247.1 - 1.2e-51 174.9 0.2 1.8e-51 174.4 0.2 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EWM25247.1 - 0.00019 20.9 0.7 0.00036 20.0 0.5 1.5 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 EWM25247.1 - 0.00044 19.9 0.3 0.001 18.8 0.2 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EWM25247.1 - 0.0022 17.5 0.1 0.004 16.7 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.1 EWM25247.1 - 0.012 15.4 0.8 0.019 14.7 0.6 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 EWM25247.1 - 0.057 14.0 0.9 0.13 12.9 0.7 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 EWM25247.1 - 0.13 12.9 3.3 0.23 12.1 2.3 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat RBD-FIP PF09457.5 EWM25248.1 - 0.16 11.7 0.3 0.21 11.4 0.2 1.1 1 0 0 1 1 1 0 FIP domain IF-2 PF11987.3 EWM25249.1 - 1.2e-05 25.1 0.0 1.4e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Translation-initiation factor 2 zf-Nse PF11789.3 EWM25252.1 - 3.8e-08 32.7 0.7 5.3e-08 32.2 0.5 1.2 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EWM25252.1 - 0.0074 15.9 0.2 0.011 15.4 0.1 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EWM25252.1 - 0.03 14.3 0.6 0.045 13.7 0.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) IBR PF01485.16 EWM25252.1 - 0.052 13.4 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 IBR domain Sigma70_r4 PF04545.11 EWM25252.1 - 0.064 12.5 0.1 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Mu-like_Com PF10122.4 EWM25252.1 - 0.079 12.0 0.6 0.11 11.5 0.4 1.4 1 1 0 1 1 1 0 Mu-like prophage protein Com zf-C2HC PF01530.13 EWM25252.1 - 0.082 12.6 0.7 0.16 11.6 0.5 1.5 1 0 0 1 1 1 0 Zinc finger, C2HC type zf-C3HC4 PF00097.20 EWM25252.1 - 0.12 12.0 0.1 0.22 11.2 0.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_S27 PF01599.14 EWM25252.1 - 0.17 11.7 1.1 7 6.5 0.0 2.5 3 0 0 3 3 3 0 Ribosomal protein S27a CENP-O PF09496.5 EWM25253.1 - 0.069 13.3 0.0 0.11 12.7 0.0 1.4 1 1 0 1 1 1 0 Cenp-O kinetochore centromere component Tubulin_C PF03953.12 EWM25254.1 - 2.8e-18 66.1 0.1 3.2e-18 65.9 0.1 1.1 1 0 0 1 1 1 1 Tubulin C-terminal domain Ribosomal_L2_C PF03947.13 EWM25256.1 - 8.8e-06 25.5 3.9 8.8e-06 25.5 2.7 2.2 1 1 1 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EWM25257.1 - 7e-06 25.9 0.0 7e-06 25.9 0.0 1.5 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Med7 PF05983.6 EWM25259.1 - 0.069 12.9 0.0 0.095 12.4 0.0 1.3 1 1 0 1 1 1 0 MED7 protein COG7 PF10191.4 EWM25260.1 - 8e-11 40.6 0.0 9.5e-11 40.3 0.0 1.0 1 0 0 1 1 1 1 Golgi complex component 7 (COG7) FAD_binding_2 PF00890.19 EWM25262.1 - 0.059 12.2 0.1 0.096 11.5 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain YWFCY PF14293.1 EWM25263.1 - 0.031 14.0 0.3 0.051 13.4 0.2 1.3 1 0 0 1 1 1 0 YWFCY protein Vps4_C PF09336.5 EWM25264.1 - 3e-11 43.0 0.0 4.1e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain IBR PF01485.16 EWM25264.1 - 0.0092 15.8 0.4 0.014 15.2 0.3 1.4 1 1 0 1 1 1 1 IBR domain TF_Zn_Ribbon PF08271.7 EWM25264.1 - 0.24 10.7 3.5 0.25 10.6 0.8 2.2 3 0 0 3 3 3 0 TFIIB zinc-binding Auto_anti-p27 PF06677.7 EWM25264.1 - 0.61 9.8 3.6 1.1 9.0 2.5 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) MIT PF04212.13 EWM25266.1 - 9.1e-14 51.0 0.4 1.5e-13 50.3 0.3 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_7 PF13176.1 EWM25266.1 - 0.029 14.1 0.5 0.21 11.4 0.1 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EWM25266.1 - 0.099 12.2 1.4 0.26 10.9 0.5 2.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EWM25266.1 - 0.12 12.2 0.7 0.45 10.5 0.5 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 EWM25266.1 - 0.19 11.6 1.8 0.33 10.8 0.8 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 EWM25266.1 - 0.2 11.3 0.8 0.51 10.0 0.6 1.8 1 1 0 1 1 1 0 TPR repeat VRR_NUC PF08774.6 EWM25267.1 - 4.4e-06 26.6 0.0 6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 VRR-NUC domain 5-FTHF_cyc-lig PF01812.15 EWM25268.1 - 7.7e-35 120.3 0.0 1.1e-34 119.8 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family 5-FTHF_cyc-lig PF01812.15 EWM25269.1 - 7.7e-35 120.3 0.0 1.1e-34 119.8 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family DUF357 PF04010.8 EWM25270.1 - 0.055 13.1 0.4 0.91 9.2 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF357) DUF357 PF04010.8 EWM25271.1 - 0.023 14.3 0.3 0.41 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF357) zf-ZPR1 PF03367.8 EWM25273.1 - 0.0073 15.4 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 ZPR1 zinc-finger domain SWI-SNF_Ssr4 PF08549.5 EWM25273.1 - 0.024 12.9 0.0 0.029 12.6 0.0 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) zf-ZPR1 PF03367.8 EWM25274.1 - 1.5e-39 134.7 0.2 2.1e-39 134.2 0.2 1.1 1 0 0 1 1 1 1 ZPR1 zinc-finger domain HTH_12 PF08461.5 EWM25274.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain LCM PF04072.9 EWM25275.1 - 9.3e-24 83.9 0.4 1.7e-23 83.1 0.3 1.4 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Glt_symporter PF03616.9 EWM25278.1 - 0.0039 15.7 0.0 0.0041 15.6 0.0 1.0 1 0 0 1 1 1 1 Sodium/glutamate symporter DUF2188 PF09954.4 EWM25279.1 - 0.044 13.6 0.5 4.3 7.3 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) Thioredoxin PF00085.15 EWM25280.1 - 8.1e-10 38.3 0.0 1.1e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EWM25280.1 - 0.021 15.0 0.4 0.08 13.1 0.3 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain Rad60-SLD PF11976.3 EWM25283.1 - 0.045 13.4 0.0 1 9.1 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like G-alpha PF00503.15 EWM25283.1 - 2.9 6.4 5.4 4.2 5.9 3.8 1.2 1 0 0 1 1 1 0 G-protein alpha subunit DUF3336 PF11815.3 EWM25284.1 - 4.8e-37 126.6 0.4 8.5e-37 125.8 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EWM25284.1 - 3.6e-09 36.8 2.2 3.6e-09 36.8 1.5 1.7 2 0 0 2 2 2 1 Patatin-like phospholipase DUF1680 PF07944.7 EWM25284.1 - 0.065 11.4 0.3 0.11 10.7 0.2 1.3 1 0 0 1 1 1 0 Putative glycosyl hydrolase of unknown function (DUF1680) SR-25 PF10500.4 EWM25286.1 - 0.39 10.1 3.8 0.44 9.9 2.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FKBP_C PF00254.23 EWM25288.1 - 1.1e-13 50.9 0.0 1.5e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase p450 PF00067.17 EWM25289.1 - 7.1e-71 239.0 0.0 8.9e-71 238.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TPR_20 PF14561.1 EWM25289.1 - 0.082 13.0 0.1 1.9 8.6 0.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF2162 PF09930.4 EWM25289.1 - 0.099 11.7 0.1 0.18 10.9 0.1 1.3 1 0 0 1 1 1 0 Predicted transporter (DUF2162) adh_short PF00106.20 EWM25290.1 - 1.7e-13 50.7 0.5 6.6e-13 48.9 0.3 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EWM25290.1 - 1.8e-05 24.4 0.0 3.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EWM25290.1 - 0.00042 20.0 0.2 0.00087 19.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EWM25290.1 - 0.087 12.8 0.1 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Pkinase PF00069.20 EWM25293.1 - 3.9e-70 235.9 0.0 4.7e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM25293.1 - 8.2e-31 107.0 0.0 1.1e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EWM25293.1 - 6.6e-06 25.2 0.0 2.7e-05 23.2 0.0 1.9 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 EWM25293.1 - 1.2e-05 24.7 0.7 1.8e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 EWM25293.1 - 0.0027 17.4 4.2 0.003 17.3 0.1 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EWM25293.1 - 0.028 13.4 0.1 0.042 12.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EWM25293.1 - 0.075 11.8 0.0 0.28 9.9 0.0 1.7 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase SNF2_N PF00176.18 EWM25294.1 - 7.4e-56 189.1 0.0 9e-56 188.8 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EWM25294.1 - 3.6e-16 58.7 0.0 7.2e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EWM25294.1 - 3.7e-05 23.2 0.0 6.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EWM25294.1 - 0.00013 21.8 0.0 0.00096 19.0 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 EWM25294.1 - 0.00079 18.3 0.0 0.0011 17.8 0.0 1.3 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 UAA PF08449.6 EWM25295.1 - 4.2e-12 45.6 22.3 7.2e-12 44.8 15.5 1.3 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 EWM25295.1 - 7.6e-11 41.8 9.6 7.6e-11 41.8 6.7 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 EWM25295.1 - 0.00052 20.0 31.8 0.013 15.4 7.6 3.0 2 1 0 2 2 2 2 EamA-like transporter family Peptidase_S26 PF10502.4 EWM25296.1 - 1.5e-13 50.4 0.0 2.4e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 EWM25296.1 - 2.4e-13 49.4 0.1 8.5e-13 47.7 0.1 1.9 1 1 0 1 1 1 1 Peptidase S24-like DUF1961 PF09224.6 EWM25296.1 - 0.086 11.9 0.0 0.19 10.7 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1961) DUF3449 PF11931.3 EWM25297.1 - 5.2e-74 248.0 1.3 9e-74 247.2 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) Telomere_Sde2_2 PF13297.1 EWM25297.1 - 5.6e-26 89.5 3.3 5.6e-26 89.5 2.3 1.8 2 0 0 2 2 2 1 Telomere stability C-terminal SF3a60_bindingd PF12108.3 EWM25297.1 - 2.5e-06 26.9 0.1 6.4e-06 25.6 0.1 1.8 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain Desulfoferrod_N PF06397.7 EWM25297.1 - 0.26 10.6 1.2 0.58 9.5 0.9 1.5 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain DUF4637 PF15470.1 EWM25298.1 - 0.29 10.7 4.1 0.073 12.6 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) DNA_ligase_A_N PF04675.9 EWM25299.1 - 1.1e-27 97.0 0.0 1.3e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 DNA ligase N terminus SMP PF04927.7 EWM25300.1 - 0.057 13.3 3.1 0.2 11.6 2.1 2.1 1 1 0 1 1 1 0 Seed maturation protein DUF959 PF06121.9 EWM25300.1 - 0.1 12.2 1.0 0.12 11.9 0.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF959) BRCT PF00533.21 EWM25301.1 - 2.4e-06 27.5 0.3 0.0043 17.1 0.0 4.1 4 1 0 4 4 4 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EWM25301.1 - 0.0033 17.2 0.1 0.024 14.4 0.0 2.2 2 0 0 2 2 2 1 twin BRCT domain GFO_IDH_MocA PF01408.17 EWM25302.1 - 2.7e-19 69.8 0.4 5.4e-19 68.8 0.1 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 EWM25302.1 - 0.03 14.7 0.0 0.05 14.0 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Arf PF00025.16 EWM25302.1 - 0.15 11.2 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family TFIIB PF00382.14 EWM25303.1 - 5.3e-26 90.2 9.4 4.3e-14 52.0 0.1 3.6 4 0 0 4 4 4 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EWM25303.1 - 8.7e-14 51.5 1.5 8.7e-14 51.5 1.0 3.2 3 0 0 3 3 3 1 Brf1-like TBP-binding domain RRN7 PF11781.3 EWM25303.1 - 0.0003 20.2 0.1 0.00073 18.9 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 TF_Zn_Ribbon PF08271.7 EWM25303.1 - 0.0022 17.2 1.8 0.0047 16.2 1.2 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_Tnp_ISL3 PF13542.1 EWM25303.1 - 0.04 13.0 0.0 0.14 11.3 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Sulfate_transp PF00916.15 EWM25304.1 - 1.4e-38 132.5 4.9 1.4e-38 132.5 3.4 1.6 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EWM25304.1 - 8e-15 54.2 4.8 8e-15 54.2 3.3 2.8 2 1 1 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EWM25304.1 - 0.0018 17.6 0.0 0.0037 16.6 0.0 1.4 1 0 0 1 1 1 1 STAS domain Antifungal_prot PF11402.3 EWM25305.1 - 0.047 13.8 0.3 0.076 13.2 0.2 1.2 1 0 0 1 1 1 0 Antifungal protein N_Asn_amidohyd PF14736.1 EWM25306.1 - 7.4e-27 93.9 0.9 1.6e-16 59.9 0.1 3.1 2 1 0 2 2 2 2 Protein N-terminal asparagine amidohydrolase DUF4079 PF13301.1 EWM25307.1 - 1.9e-47 161.5 0.3 3.2e-47 160.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4079) HTH_Tnp_IS1 PF12759.2 EWM25307.1 - 0.12 11.7 0.0 0.45 9.9 0.0 1.9 1 0 0 1 1 1 0 InsA C-terminal domain ATPase_gene1 PF09527.5 EWM25307.1 - 0.17 11.6 6.0 1.1 9.1 0.1 3.5 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit (ATPase_gene1) IF-2B PF01008.12 EWM25308.1 - 1.5e-59 201.3 0.0 2.8e-59 200.4 0.0 1.4 1 1 0 1 1 1 1 Initiation factor 2 subunit family SAP PF02037.22 EWM25309.1 - 0.0009 18.6 0.2 0.0023 17.4 0.1 1.7 1 0 0 1 1 1 1 SAP domain GTP_EFTU PF00009.22 EWM25310.1 - 2.7e-47 160.6 0.7 4.4e-47 159.9 0.5 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 EWM25310.1 - 1.3e-38 131.2 4.1 2.6e-38 130.2 2.8 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 EWM25310.1 - 2.3e-15 56.2 0.0 5.4e-15 55.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EWM25310.1 - 0.00044 20.0 0.0 0.0012 18.6 0.0 1.8 1 1 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.17 EWM25310.1 - 0.00073 18.9 0.1 0.0013 18.1 0.1 1.4 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EWM25310.1 - 0.0067 15.6 0.0 0.028 13.6 0.0 2.0 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU_D2 PF03144.20 EWM25310.1 - 0.019 15.0 0.1 0.051 13.6 0.0 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 2 Miro PF08477.8 EWM25310.1 - 0.078 13.4 0.1 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Helicase_C PF00271.26 EWM25311.1 - 2.3e-16 59.4 0.0 3.7e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EWM25311.1 - 2.6e-09 36.2 0.1 3.2e-09 36.0 0.1 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain AP2 PF00847.15 EWM25312.1 - 6.3e-22 77.4 10.1 1.3e-10 41.2 0.6 3.8 4 0 0 4 4 4 3 AP2 domain DUF3143 PF11341.3 EWM25312.1 - 0.029 14.2 0.9 7 6.6 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3143) DUF756 PF05506.7 EWM25312.1 - 0.072 13.5 0.3 0.21 12.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF756) adh_short PF00106.20 EWM25314.1 - 1.1e-25 90.5 0.0 1.6e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EWM25314.1 - 2.8e-09 36.9 0.0 3.9e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EWM25314.1 - 4.2e-09 36.5 0.0 6.1e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EWM25314.1 - 6.1e-07 28.8 0.0 1e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EWM25314.1 - 0.00011 22.2 0.0 0.00024 21.1 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EWM25314.1 - 0.038 13.4 0.0 0.68 9.3 0.0 2.5 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family PGM_PMM_I PF02878.11 EWM25315.1 - 1.1e-32 112.4 0.1 4.5e-32 110.4 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EWM25315.1 - 5.5e-26 90.8 0.0 1.4e-25 89.5 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EWM25315.1 - 1.9e-11 44.2 0.4 8.3e-10 38.9 0.4 3.2 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EWM25315.1 - 1.6e-07 31.2 0.0 3.8e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain U-box PF04564.10 EWM25316.1 - 1.2e-07 31.5 0.0 2.3e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 U-box domain SapB_1 PF05184.10 EWM25318.1 - 0.02 14.6 0.0 9.5 6.1 0.0 2.8 2 1 1 3 3 3 0 Saposin-like type B, region 1 DUF1641 PF07849.6 EWM25318.1 - 0.1 12.2 1.1 7.5 6.2 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1641) PSD4 PF07631.6 EWM25318.1 - 0.1 12.9 13.3 2.5 8.4 0.5 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1592) Neogenin_C PF06583.7 EWM25318.1 - 0.29 10.6 5.6 0.088 12.3 1.5 1.7 1 1 1 2 2 2 0 Neogenin C-terminus DUF241 PF03087.9 EWM25318.1 - 0.37 10.2 6.6 0.36 10.2 0.2 2.1 2 0 0 2 2 2 0 Arabidopsis protein of unknown function MMPL PF03176.10 EWM25318.1 - 0.54 8.9 10.5 0.67 8.6 4.0 2.3 1 1 1 2 2 2 0 MMPL family PDGLE PF13190.1 EWM25318.1 - 0.88 9.2 7.6 8.4 6.1 0.0 3.7 1 1 1 3 3 3 0 PDGLE domain Uteroglobin PF01099.12 EWM25318.1 - 1.3 8.8 5.0 8.3 6.2 0.1 2.9 2 0 0 2 2 2 0 Uteroglobin family RhoGEF PF00621.15 EWM25318.1 - 2.7 7.8 5.9 52 3.6 4.1 2.4 1 1 0 1 1 1 0 RhoGEF domain Imm31 PF15595.1 EWM25318.1 - 3.1 7.6 7.0 4.1 7.2 1.2 3.0 2 1 1 3 3 3 0 Immunity protein 31 DUF4618 PF15397.1 EWM25318.1 - 8.2 5.6 11.2 0.17 11.1 1.7 2.3 1 1 1 3 3 3 0 Domain of unknown function (DUF4618) FYVE PF01363.16 EWM25320.1 - 4.6e-15 55.2 7.4 8.4e-15 54.4 5.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger PH_6 PF15406.1 EWM25320.1 - 0.0076 16.3 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain IBR PF01485.16 EWM25320.1 - 0.11 12.4 5.1 0.092 12.6 1.8 2.1 2 0 0 2 2 2 0 IBR domain C1_4 PF07975.7 EWM25320.1 - 1.5 8.8 7.9 4.9 7.2 5.5 1.9 1 0 0 1 1 1 0 TFIIH C1-like domain FYVE_2 PF02318.11 EWM25320.1 - 6.1 6.7 13.7 1.1 9.1 5.3 2.5 2 1 1 3 3 3 0 FYVE-type zinc finger V-ATPase_H_N PF03224.9 EWM25321.1 - 0.081 12.0 0.3 0.091 11.8 0.2 1.0 1 0 0 1 1 1 0 V-ATPase subunit H Ras PF00071.17 EWM25322.1 - 4.9e-57 191.8 0.0 5.8e-57 191.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EWM25322.1 - 3.4e-18 66.2 0.0 8.7e-18 64.9 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EWM25322.1 - 3e-14 52.6 0.0 3.8e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EWM25322.1 - 0.00073 19.0 0.0 0.0029 17.0 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EWM25322.1 - 0.0019 17.3 0.0 0.0021 17.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EWM25322.1 - 0.0054 16.6 0.0 0.0094 15.8 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase KaiC PF06745.8 EWM25322.1 - 0.0097 15.0 0.0 0.64 9.0 0.0 2.1 2 0 0 2 2 2 1 KaiC WD40 PF00400.27 EWM25324.1 - 1.1e-19 69.4 11.6 7.2e-06 25.6 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat HIRA_B PF09453.5 EWM25324.1 - 0.0034 16.9 3.2 0.081 12.5 0.4 2.7 2 0 0 2 2 2 1 HIRA B motif eIF2A PF08662.6 EWM25324.1 - 0.0063 16.2 0.0 0.17 11.5 0.0 2.8 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EWM25324.1 - 0.26 10.0 0.0 0.94 8.1 0.0 1.9 1 1 0 1 1 1 0 Nup133 N terminal like PD40 PF07676.7 EWM25324.1 - 1 9.1 3.9 30 4.4 0.4 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Mito_carr PF00153.22 EWM25325.1 - 2.1e-35 120.3 0.2 2.3e-16 59.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyoxalase PF00903.20 EWM25331.1 - 1.5e-08 34.7 0.0 0.001 19.0 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EWM25331.1 - 1.2e-06 29.0 0.0 0.027 15.0 0.0 2.5 2 1 0 2 2 2 2 Glyoxalase-like domain TRAM_LAG1_CLN8 PF03798.11 EWM25332.1 - 8.2e-27 94.0 2.0 1.1e-26 93.5 1.4 1.2 1 0 0 1 1 1 1 TLC domain DUF2530 PF10745.4 EWM25332.1 - 0.62 10.0 2.8 0.44 10.5 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Activator_LAG-3 PF11498.3 EWM25333.1 - 0.06 12.0 7.5 0.12 11.1 5.2 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Band_7 PF01145.20 EWM25334.1 - 2.4e-28 99.2 0.0 3.7e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family WD40 PF00400.27 EWM25335.1 - 8.9e-19 66.6 7.2 4.1e-07 29.6 0.1 6.0 6 1 0 6 6 6 4 WD domain, G-beta repeat E1_dh PF00676.15 EWM25336.1 - 6.6e-89 297.5 0.0 8.2e-89 297.2 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.16 EWM25336.1 - 9.5e-07 27.9 0.0 1.3e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain TPP_enzyme_C PF02775.16 EWM25336.1 - 8.8e-05 22.1 0.0 0.00025 20.6 0.0 1.7 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EWM25336.1 - 0.0047 15.8 0.0 0.014 14.2 0.0 1.7 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Amidase02_C PF12123.3 EWM25336.1 - 0.014 15.0 0.6 0.027 14.1 0.4 1.5 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase RRM_6 PF14259.1 EWM25337.1 - 1.2e-05 25.1 0.0 2.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EWM25337.1 - 0.033 13.8 0.0 0.34 10.5 0.0 2.3 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) La PF05383.12 EWM25337.1 - 0.097 12.4 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 La domain RRM_5 PF13893.1 EWM25337.1 - 0.14 11.9 0.0 0.38 10.6 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ECH PF00378.15 EWM25340.1 - 3.9e-74 248.8 5.4 4.5e-74 248.6 3.7 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EWM25340.1 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region PAP_assoc PF03828.14 EWM25341.1 - 1.4e-14 53.7 0.0 3.7e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EWM25341.1 - 0.014 15.6 0.0 0.085 13.2 0.0 2.2 2 0 0 2 2 2 0 Nucleotidyltransferase domain SQS_PSY PF00494.14 EWM25341.1 - 0.035 13.3 0.0 0.074 12.3 0.0 1.5 1 0 0 1 1 1 0 Squalene/phytoene synthase DnaJ PF00226.26 EWM25343.1 - 5.3e-19 67.7 0.2 5.3e-19 67.7 0.1 2.7 3 0 0 3 3 3 1 DnaJ domain Glu_syn_central PF04898.9 EWM25343.1 - 0.022 14.0 0.7 0.13 11.4 0.1 2.2 1 1 2 3 3 3 0 Glutamate synthase central domain GTP_EFTU PF00009.22 EWM25343.1 - 0.14 11.5 0.1 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain PI3_PI4_kinase PF00454.22 EWM25344.1 - 2e-29 102.7 0.0 1.5e-28 99.8 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FYVE PF01363.16 EWM25344.1 - 0.00071 19.4 4.9 0.0017 18.1 3.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 EWM25344.1 - 0.1 12.8 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 PH domain DUF3727 PF12527.3 EWM25345.1 - 8.2e-06 25.8 5.3 0.1 12.6 0.1 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF3727) Radial_spoke PF04712.7 EWM25345.1 - 0.057 12.1 1.4 0.073 11.8 1.0 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Upf2 PF04050.9 EWM25345.1 - 0.12 12.0 10.5 0.18 11.5 7.3 1.2 1 0 0 1 1 1 0 Up-frameshift suppressor 2 Nop14 PF04147.7 EWM25345.1 - 0.26 9.1 7.4 0.32 8.8 5.1 1.0 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 EWM25345.1 - 1.1 8.7 9.9 1.7 8.1 6.9 1.2 1 0 0 1 1 1 0 Nucleoplasmin Prothymosin PF03247.9 EWM25345.1 - 4.9 7.3 20.9 8.5 6.5 14.5 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family NOA36 PF06524.7 EWM25345.1 - 8.3 5.5 7.7 11 5.1 5.3 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2890 PF11081.3 EWM25345.1 - 9.2 6.2 10.5 14 5.6 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Ribosomal_L44 PF00935.14 EWM25346.1 - 2.4e-33 113.9 14.2 3.8e-33 113.3 9.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 CDP-OH_P_transf PF01066.16 EWM25347.1 - 1.8e-15 57.0 8.1 1.8e-15 57.0 5.6 2.9 2 2 1 3 3 3 1 CDP-alcohol phosphatidyltransferase PalH PF08733.5 EWM25347.1 - 1 8.1 5.2 0.98 8.1 2.6 1.6 2 0 0 2 2 2 0 PalH/RIM21 DOT1 PF08123.8 EWM25348.1 - 0.0025 17.1 0.0 0.0058 15.9 0.0 1.7 2 0 0 2 2 2 1 Histone methylation protein DOT1 zf-C2H2 PF00096.21 EWM25348.1 - 0.018 15.3 1.3 0.018 15.3 0.9 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type TPR_11 PF13414.1 EWM25349.1 - 6.6e-15 54.5 5.5 5.5e-05 22.7 0.0 6.1 6 1 0 6 6 6 3 TPR repeat TPR_1 PF00515.23 EWM25349.1 - 2.3e-09 36.4 2.2 0.59 9.8 0.0 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.12 EWM25349.1 - 7.3e-09 34.8 9.1 10 6.2 0.0 9.9 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_12 PF13424.1 EWM25349.1 - 9.1e-07 28.7 10.8 0.33 10.8 0.0 8.1 9 1 0 9 9 9 2 Tetratricopeptide repeat Apc3 PF12895.2 EWM25349.1 - 3.3e-06 27.1 0.0 0.036 14.1 0.0 4.9 5 1 0 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EWM25349.1 - 6.9e-06 26.3 22.2 0.0005 20.3 0.0 6.6 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 EWM25349.1 - 3.8e-05 23.1 1.2 1.1 9.2 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EWM25349.1 - 4.9e-05 23.5 27.7 1.1 10.1 0.2 10.2 8 2 1 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.1 EWM25349.1 - 0.00018 21.0 0.0 4.3 7.3 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat NARP1 PF12569.3 EWM25349.1 - 0.00037 19.3 0.0 0.00095 18.0 0.0 1.7 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_17 PF13431.1 EWM25349.1 - 0.00045 20.2 0.0 0.22 11.7 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EWM25349.1 - 0.018 15.4 4.2 1e+02 3.6 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 EWM25349.1 - 0.098 13.3 25.5 1.2 9.9 0.0 8.2 6 2 1 7 7 7 0 Tetratricopeptide repeat DUF1003 PF06210.6 EWM25351.1 - 1.1e-30 105.7 0.0 2e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1003) DUF89 PF01937.14 EWM25352.1 - 5.9e-88 295.0 0.0 7.2e-88 294.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Hydrolase_6 PF13344.1 EWM25353.1 - 4.3e-28 97.1 0.0 1e-27 95.9 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EWM25353.1 - 3.1e-14 52.4 0.0 5.9e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EWM25353.1 - 4.3e-12 46.8 0.0 1e-11 45.6 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EWM25353.1 - 1.3e-08 35.2 0.1 0.00012 22.3 0.0 2.8 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Lycopene_cycl PF05834.7 EWM25354.1 - 3.1e-79 266.5 0.0 5.1e-79 265.8 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DUF814 PF05670.8 EWM25354.1 - 3.7e-17 61.9 0.0 8.2e-17 60.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Trp_halogenase PF04820.9 EWM25354.1 - 2.8e-08 32.8 0.7 0.0017 17.0 0.0 2.5 3 0 0 3 3 3 2 Tryptophan halogenase Thi4 PF01946.12 EWM25354.1 - 0.00062 18.9 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 EWM25354.1 - 0.00062 18.9 5.3 0.0047 16.0 0.1 2.6 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.1 EWM25354.1 - 0.0018 18.2 0.0 0.005 16.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EWM25354.1 - 0.0019 18.0 0.5 0.0045 16.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EWM25354.1 - 0.0021 16.6 3.1 0.0027 16.2 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 EWM25354.1 - 0.0031 17.5 0.9 0.36 10.8 0.1 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EWM25354.1 - 0.0035 16.2 0.1 0.11 11.3 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EWM25354.1 - 0.0054 15.8 0.3 0.021 13.8 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EWM25354.1 - 0.019 14.7 0.0 0.12 12.0 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.17 EWM25354.1 - 0.048 12.5 0.0 0.099 11.4 0.0 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EWM25354.1 - 0.092 11.5 0.1 0.18 10.6 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 EWM25354.1 - 0.24 11.0 0.0 0.24 11.0 0.0 1.7 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Mito_carr PF00153.22 EWM25355.1 - 4.5e-55 183.3 1.6 4.3e-18 64.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 EWM25356.1 - 1.3e-14 54.3 2.9 2.5e-14 53.4 2.0 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.4 EWM25356.1 - 0.11 12.5 0.1 0.11 12.5 0.1 2.6 2 1 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide PARP PF00644.15 EWM25357.1 - 1.3e-06 28.0 0.2 2.3e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Chloroa_b-bind PF00504.16 EWM25359.1 - 3.1e-36 124.9 0.1 6.2e-36 124.0 0.0 1.4 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Med3 PF11593.3 EWM25359.1 - 0.16 11.1 7.9 0.18 11.0 5.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Totivirus_coat PF05518.6 EWM25359.1 - 1 7.0 10.2 1.3 6.7 7.1 1.1 1 0 0 1 1 1 0 Totivirus coat protein peroxidase PF00141.18 EWM25361.1 - 5.4e-44 150.3 0.0 7e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 Peroxidase Complex1_LYR PF05347.10 EWM25362.1 - 6.2e-09 35.5 0.7 9.7e-09 34.8 0.2 1.6 1 1 1 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EWM25362.1 - 1.4e-08 34.8 0.2 2.1e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like DHHA2 PF02833.9 EWM25363.1 - 4.5e-12 46.2 0.0 7.6e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 EWM25363.1 - 3.2e-07 30.1 0.0 2.3e-06 27.3 0.0 2.2 1 1 0 1 1 1 1 DHH family DUF1424 PF07232.6 EWM25363.1 - 0.16 10.7 0.0 0.3 9.8 0.0 1.3 1 0 0 1 1 1 0 Putative rep protein (DUF1424) FAA_hydrolase PF01557.13 EWM25364.1 - 1e-48 165.6 0.0 1.5e-48 165.1 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 EWM25364.1 - 1.9e-29 101.7 0.0 4.5e-29 100.5 0.0 1.6 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal GST_N_3 PF13417.1 EWM25364.1 - 2.7e-19 69.1 0.0 6.3e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EWM25364.1 - 9.7e-14 51.1 0.0 2e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EWM25364.1 - 1.6e-13 50.5 0.0 3.5e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EWM25364.1 - 6.9e-05 23.2 0.0 0.0002 21.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EWM25364.1 - 7.5e-05 22.5 0.0 0.0002 21.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EWM25364.1 - 0.00015 21.6 0.0 0.00033 20.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3381 PF11861.3 EWM25365.1 - 1.5 8.2 5.1 29 4.1 2.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3381) IGPS PF00218.16 EWM25366.1 - 1.2e-30 106.4 0.0 1.5e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase ThiG PF05690.9 EWM25366.1 - 1.5e-05 24.2 5.0 0.0052 15.8 0.2 2.3 1 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.12 EWM25366.1 - 0.039 12.7 1.6 0.51 9.1 0.0 2.5 3 0 0 3 3 3 0 Dihydrouridine synthase (Dus) FMN_dh PF01070.13 EWM25366.1 - 0.23 10.2 3.7 12 4.6 0.0 3.6 3 1 1 4 4 4 0 FMN-dependent dehydrogenase IMPDH PF00478.20 EWM25366.1 - 0.35 9.7 3.7 0.69 8.7 0.2 2.6 1 1 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain HeH PF12949.2 EWM25367.1 - 1.2e-05 24.7 1.2 1.2e-05 24.7 0.8 2.0 2 0 0 2 2 2 1 HeH/LEM domain Mito_carr PF00153.22 EWM25368.1 - 3.8e-52 173.9 5.7 3.3e-17 61.9 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.20 EWM25369.1 - 1.2e-58 198.3 0.0 1.6e-58 197.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM25369.1 - 8.7e-23 80.6 0.1 2e-22 79.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EWM25369.1 - 2.6e-06 26.6 0.0 0.00047 19.2 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EWM25369.1 - 0.0013 18.5 0.2 0.0047 16.6 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EWM25369.1 - 0.012 15.2 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 EWM25369.1 - 0.016 14.2 0.1 0.034 13.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.6 EWM25369.1 - 0.21 10.1 0.4 0.34 9.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) SnoaL_4 PF13577.1 EWM25371.1 - 0.055 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain SnoaL_2 PF12680.2 EWM25371.1 - 0.081 13.3 0.0 0.18 12.2 0.0 1.8 1 1 0 1 1 1 0 SnoaL-like domain Ank_2 PF12796.2 EWM25372.1 - 3.3e-16 59.3 0.3 5.8e-16 58.6 0.2 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EWM25372.1 - 1.7e-14 53.5 0.7 9.2e-10 38.4 0.1 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EWM25372.1 - 8.6e-10 38.8 0.1 7.5e-06 26.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EWM25372.1 - 1.7e-07 30.6 2.0 0.0021 17.7 0.1 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 EWM25372.1 - 1e-06 28.3 0.3 0.074 13.3 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat DUF2279 PF10043.4 EWM25373.1 - 0.064 13.5 0.0 0.082 13.1 0.0 1.2 1 0 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2279) DUF1356 PF07092.7 EWM25374.1 - 0.0025 17.0 0.0 0.0045 16.2 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1356) MPC PF03650.8 EWM25375.1 - 4.9e-31 107.1 1.3 7.1e-31 106.6 0.9 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Ank_2 PF12796.2 EWM25376.1 - 1.5e-88 291.2 4.0 1.3e-16 60.6 0.0 7.1 6 0 0 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EWM25376.1 - 3.2e-58 190.7 17.9 6.6e-08 31.9 0.0 16.2 17 0 0 17 17 17 13 Ankyrin repeat Ank_4 PF13637.1 EWM25376.1 - 3.2e-53 177.2 12.1 4.8e-07 30.1 0.0 10.5 7 3 2 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 EWM25376.1 - 1.5e-41 139.4 21.1 1e-05 25.6 0.0 11.1 6 3 4 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM25376.1 - 5.3e-32 106.6 14.4 1.8e-05 24.5 0.0 13.7 15 0 0 15 15 15 7 Ankyrin repeat cNMP_binding PF00027.24 EWM25376.1 - 3e-18 65.3 0.1 4.8e-10 39.1 0.1 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ank_2 PF12796.2 EWM25377.1 - 4.7e-34 116.5 0.1 3.4e-18 65.7 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EWM25377.1 - 3.5e-32 108.5 0.1 7.9e-07 28.5 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 EWM25377.1 - 5.9e-24 83.9 0.5 3.4e-08 33.7 0.0 4.2 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EWM25377.1 - 3e-21 74.9 0.4 1.3e-06 28.3 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM25377.1 - 5.3e-21 72.6 0.0 9.5e-05 22.2 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat BT1 PF03092.11 EWM25378.1 - 2.6e-115 385.5 6.3 3.4e-115 385.1 4.3 1.1 1 0 0 1 1 1 1 BT1 family MFS_1 PF07690.11 EWM25378.1 - 7.6e-14 51.1 44.5 1.4e-10 40.4 21.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Transgly PF00912.17 EWM25378.1 - 0.0021 17.3 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase DUF1674 PF07896.7 EWM25379.1 - 3.3e-10 40.0 5.2 7.3e-10 38.9 3.6 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) PGA2 PF07543.7 EWM25379.1 - 0.016 15.0 0.9 0.02 14.6 0.6 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 Pro_isomerase PF00160.16 EWM25380.1 - 1.8e-12 47.7 0.0 3.2e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF155 PF02582.9 EWM25381.1 - 2.1e-49 167.8 0.0 3.2e-49 167.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 GRP PF07172.6 EWM25381.1 - 0.0066 16.9 3.3 0.0066 16.9 2.3 2.1 2 0 0 2 2 2 1 Glycine rich protein family ABC_tran PF00005.22 EWM25382.1 - 1.2e-47 161.6 0.0 3.3e-23 82.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.19 EWM25382.1 - 8e-28 97.0 23.3 8e-28 97.0 16.2 2.4 3 0 0 3 3 2 1 ABC-2 type transporter AAA_21 PF13304.1 EWM25382.1 - 4.2e-17 63.0 1.3 2.9e-06 27.4 0.1 4.3 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EWM25382.1 - 3.4e-11 42.4 0.9 6.4e-05 22.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EWM25382.1 - 2.8e-10 40.4 0.0 0.0005 20.1 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EWM25382.1 - 1.5e-09 37.2 0.0 0.00045 19.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EWM25382.1 - 1.7e-09 37.3 0.5 0.0019 17.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.14 EWM25382.1 - 3e-06 26.6 0.0 0.00015 21.0 0.0 2.9 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EWM25382.1 - 6.2e-06 27.0 0.0 0.038 14.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EWM25382.1 - 9.8e-06 25.7 0.3 0.26 11.4 0.0 3.0 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EWM25382.1 - 1.7e-05 24.9 0.0 0.056 13.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 EWM25382.1 - 1.8e-05 24.7 0.7 0.07 13.0 0.2 2.4 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EWM25382.1 - 5.7e-05 22.3 0.1 4 6.3 0.1 3.6 4 0 0 4 4 4 0 AAA ATPase domain AAA_23 PF13476.1 EWM25382.1 - 0.00013 22.3 0.1 0.09 13.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EWM25382.1 - 0.00018 21.4 1.0 0.31 10.8 0.0 3.0 4 0 0 4 4 2 2 AAA domain AAA_18 PF13238.1 EWM25382.1 - 0.00024 21.4 1.0 0.37 11.1 0.0 2.8 3 0 0 3 3 2 2 AAA domain SbcCD_C PF13558.1 EWM25382.1 - 0.00034 20.4 0.0 0.63 9.9 0.0 2.7 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 EWM25382.1 - 0.00093 19.1 0.0 1.3 8.9 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.7 EWM25382.1 - 0.0014 18.3 0.3 0.42 10.2 0.0 2.7 2 0 0 2 2 2 1 NACHT domain Arch_ATPase PF01637.13 EWM25382.1 - 0.0015 18.2 0.0 0.0081 15.8 0.0 2.0 2 0 0 2 2 2 1 Archaeal ATPase Miro PF08477.8 EWM25382.1 - 0.0022 18.4 0.0 1.8 9.1 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein NTPase_1 PF03266.10 EWM25382.1 - 0.0023 17.6 1.1 5.7 6.6 0.0 4.0 4 0 0 4 4 4 0 NTPase AAA_30 PF13604.1 EWM25382.1 - 0.0032 17.0 0.6 0.73 9.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EWM25382.1 - 0.0045 16.7 0.2 3.2 7.5 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain ArgK PF03308.11 EWM25382.1 - 0.0048 15.7 0.4 1 8.0 0.0 2.6 3 0 0 3 3 2 1 ArgK protein AAA_10 PF12846.2 EWM25382.1 - 0.0091 15.4 3.2 0.44 9.9 0.1 2.3 2 0 0 2 2 2 1 AAA-like domain cobW PF02492.14 EWM25382.1 - 0.013 14.9 0.2 4.7 6.6 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 EWM25382.1 - 0.027 14.2 0.5 3.5 7.4 0.0 2.8 2 0 0 2 2 2 0 Dynamin family Pox_A32 PF04665.7 EWM25382.1 - 0.036 13.3 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein Zeta_toxin PF06414.7 EWM25382.1 - 0.039 13.0 1.3 2.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_14 PF13173.1 EWM25382.1 - 0.059 13.2 0.0 5.5 6.8 0.0 2.8 3 0 0 3 3 2 0 AAA domain T2SE PF00437.15 EWM25382.1 - 0.06 12.2 0.0 1.4 7.7 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Toxin_14 PF07829.6 EWM25382.1 - 0.072 12.8 0.2 0.17 11.6 0.2 1.5 1 0 0 1 1 1 0 Alpha-A conotoxin PIVA-like protein ATP-synt_ab PF00006.20 EWM25382.1 - 0.11 12.0 0.2 16 4.9 0.1 2.3 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.24 EWM25382.1 - 0.11 12.7 0.3 3.9 7.6 0.0 3.2 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EWM25382.1 - 0.11 12.2 1.0 8.5 6.0 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) MobB PF03205.9 EWM25382.1 - 0.13 11.9 0.1 2.6 7.7 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 EWM25382.1 - 0.13 11.7 0.3 8.4 5.8 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_ATPase PF09818.4 EWM25382.1 - 0.14 10.6 0.9 1.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Predicted ATPase of the ABC class IstB_IS21 PF01695.12 EWM25382.1 - 0.15 11.4 0.1 11 5.3 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein UPF0079 PF02367.12 EWM25382.1 - 0.44 10.1 3.3 11 5.6 0.1 3.1 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 DUF4519 PF15012.1 EWM25382.1 - 0.5 10.3 1.5 1.3 8.9 1.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) ABC2_membrane_3 PF12698.2 EWM25382.1 - 0.68 8.8 31.8 0.38 9.7 14.5 2.6 1 1 1 2 2 2 0 ABC-2 family transporter protein PSII_Pbs27 PF13326.1 EWM25384.1 - 3e-32 111.6 0.0 4e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 Photosystem II Pbs27 MMR_HSR1 PF01926.18 EWM25385.1 - 3.9e-18 65.4 0.0 8.8e-18 64.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP-bdg_N PF13167.1 EWM25385.1 - 4.7e-06 26.6 0.0 9.4e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 GTP-binding GTPase N-terminal DUF258 PF03193.11 EWM25385.1 - 1.6e-05 24.1 0.0 5.6e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EWM25385.1 - 0.0012 18.1 0.2 0.011 14.9 0.1 2.4 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EWM25385.1 - 0.0022 17.4 0.0 0.25 10.7 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.14 EWM25385.1 - 0.034 13.6 0.0 0.36 10.2 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 EWM25385.1 - 0.058 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Dynamin family Ras PF00071.17 EWM25385.1 - 0.11 11.8 0.1 3.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Ras family Fumble PF03630.9 EWM25386.1 - 5.8e-115 383.7 3.4 1.8e-86 290.1 0.3 2.4 2 1 0 2 2 2 2 Fumble DUF1943 PF09172.6 EWM25386.1 - 0.075 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) MIP PF00230.15 EWM25387.1 - 1.6e-14 53.8 28.4 5.4e-09 35.8 0.2 4.7 2 2 0 3 3 3 2 Major intrinsic protein ENOD40 PF08247.6 EWM25387.1 - 0.081 12.7 1.1 0.17 11.6 0.7 1.6 1 0 0 1 1 1 0 ENOD40 protein UMPH-1 PF05822.7 EWM25388.1 - 6.4e-67 225.4 0.0 3.3e-36 124.8 0.0 2.1 2 0 0 2 2 2 2 Pyrimidine 5'-nucleotidase (UMPH-1) Glu_synthase PF01645.12 EWM25390.1 - 1e-158 528.1 0.6 8.9e-157 521.7 0.0 2.4 3 0 0 3 3 3 2 Conserved region in glutamate synthase GATase_2 PF00310.16 EWM25390.1 - 5.1e-112 374.1 0.0 1.1e-111 373.0 0.0 1.6 1 1 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 EWM25390.1 - 2.9e-108 361.5 0.0 6.3e-108 360.4 0.0 1.5 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.14 EWM25390.1 - 2.7e-61 206.0 8.1 4.4e-61 205.4 5.6 1.3 1 0 0 1 1 1 1 GXGXG motif PfkB PF00294.19 EWM25391.1 - 1.3e-58 198.5 0.3 1.5e-58 198.3 0.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EWM25391.1 - 3.2e-13 49.4 0.0 5.6e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase GSHPx PF00255.14 EWM25392.1 - 1.1e-28 98.6 0.0 1.7e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase Redoxin PF08534.5 EWM25392.1 - 0.00034 20.1 0.0 0.00095 18.7 0.0 1.7 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EWM25392.1 - 0.0018 17.9 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Methyltransf_11 PF08241.7 EWM25393.1 - 1.3e-21 76.8 0.0 2.3e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM25393.1 - 5.8e-17 61.6 0.0 8.1e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM25393.1 - 1.7e-14 53.8 0.0 2.6e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EWM25393.1 - 8.7e-14 51.2 0.0 1.1e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 EWM25393.1 - 2.4e-12 47.4 0.0 4.3e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM25393.1 - 3.5e-12 46.5 0.0 5.8e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM25393.1 - 4.1e-11 42.9 0.0 8.1e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM25393.1 - 5.8e-10 39.5 0.0 8.8e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EWM25393.1 - 2.6e-06 26.7 0.0 3.9e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EWM25393.1 - 0.0033 16.8 0.0 0.0055 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 EWM25393.1 - 0.0048 16.9 0.0 0.0091 15.9 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase MetW PF07021.7 EWM25393.1 - 0.024 13.9 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 EWM25393.1 - 0.045 13.4 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.6 EWM25393.1 - 0.095 11.3 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_24 PF13578.1 EWM25393.1 - 0.11 13.3 0.0 0.22 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.20 EWM25394.1 - 1.7e-25 89.8 0.0 2.4e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EWM25394.1 - 1.5e-12 47.8 0.0 2.1e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EWM25394.1 - 1.4e-06 28.1 0.0 2.1e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EWM25394.1 - 0.0015 18.5 0.1 0.0027 17.7 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding Glyco_tran_WecB PF03808.8 EWM25394.1 - 0.084 12.2 0.0 0.21 10.9 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family GCK PF07802.6 EWM25395.1 - 8.1e-08 32.2 2.8 1.8e-07 31.1 2.0 1.6 1 0 0 1 1 1 1 GCK domain DUF2993 PF11209.3 EWM25396.1 - 2.6e-07 30.7 4.6 5.1e-07 29.8 3.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2993) Ribosomal_S6 PF01250.12 EWM25397.1 - 9.3e-12 44.6 0.0 1.6e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S6 CBFD_NFYB_HMF PF00808.18 EWM25398.1 - 6.5e-17 61.3 0.3 1.2e-16 60.4 0.2 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EWM25398.1 - 9.4e-09 35.2 0.3 1.7e-08 34.4 0.2 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 EMG1 PF03587.9 EWM25399.1 - 4e-62 209.1 0.0 4.7e-62 208.8 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase FAD_binding_8 PF08022.7 EWM25399.1 - 0.066 13.0 0.1 0.22 11.3 0.0 1.9 2 0 0 2 2 2 0 FAD-binding domain Peptidase_C1 PF00112.18 EWM25400.1 - 3.3e-42 144.8 3.6 5e-42 144.2 2.5 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 EWM25400.1 - 0.05 12.1 1.6 0.16 10.4 0.4 1.9 2 0 0 2 2 2 0 Peptidase C1-like family YokU PF14122.1 EWM25400.1 - 0.13 12.0 0.1 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 YokU-like protein UPF0370 PF13980.1 EWM25401.1 - 0.028 14.2 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) PCI PF01399.22 EWM25402.1 - 5.6e-11 42.6 0.0 2.2e-10 40.8 0.0 2.1 2 0 0 2 2 2 1 PCI domain Skp1 PF01466.14 EWM25403.1 - 9.4e-37 124.9 0.4 1.6e-36 124.1 0.3 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EWM25403.1 - 1.9e-17 63.0 1.5 3.6e-17 62.2 1.1 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.26 EWM25403.1 - 0.03 14.3 0.2 0.47 10.4 0.0 2.3 1 1 1 2 2 2 0 BTB/POZ domain DUF3608 PF12257.3 EWM25403.1 - 0.086 11.7 0.2 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3608) SnoaL_3 PF13474.1 EWM25404.1 - 9e-21 74.1 0.0 1.5e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EWM25404.1 - 1.2e-08 35.1 0.2 4.4e-08 33.2 0.1 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4440) CaMKII_AD PF08332.5 EWM25404.1 - 6.3e-05 22.8 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II Association SnoaL_2 PF12680.2 EWM25404.1 - 0.00031 21.1 0.3 0.00069 19.9 0.2 1.6 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.1 EWM25404.1 - 0.0005 19.9 0.1 0.00094 19.0 0.1 1.4 1 0 0 1 1 1 1 SnoaL-like domain DUF1539 PF07560.6 EWM25404.1 - 0.0013 18.5 0.3 0.0033 17.2 0.0 1.7 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1539) Sigma70_ner PF04546.8 EWM25404.1 - 0.0088 15.6 1.1 0.024 14.2 0.8 1.7 1 0 0 1 1 1 1 Sigma-70, non-essential region Tenui_NS4 PF03300.8 EWM25404.1 - 0.14 11.1 0.2 0.22 10.5 0.1 1.2 1 0 0 1 1 1 0 Tenuivirus non-structural protein NS4 DUF4632 PF15451.1 EWM25404.1 - 0.91 9.4 6.0 1.4 8.9 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4632) DUF802 PF05650.6 EWM25404.1 - 3.7 7.7 7.0 9.8 6.3 4.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF802) Peptidase_M3 PF01432.15 EWM25405.1 - 8.2e-117 391.0 0.0 1e-116 390.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 EWM25405.1 - 0.054 12.8 0.3 0.087 12.1 0.2 1.2 1 0 0 1 1 1 0 Peptidase M50B-like gag_pre-integrs PF13976.1 EWM25405.1 - 0.063 12.9 0.0 0.19 11.4 0.0 1.8 1 0 0 1 1 1 0 GAG-pre-integrase domain FtsA PF14450.1 EWM25405.1 - 0.087 12.6 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Cell division protein FtsA TP6A_N PF04406.9 EWM25406.1 - 4.9e-20 70.9 0.1 1.2e-19 69.7 0.1 1.7 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2457 PF10446.4 EWM25406.1 - 0.26 9.9 26.5 0.63 8.7 4.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) RNA_pol_3_Rpc31 PF11705.3 EWM25406.1 - 4.1 7.2 20.7 0.1 12.5 4.1 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 PBP1_TM PF14812.1 EWM25406.1 - 5.9 7.2 22.6 8.2 6.8 8.1 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Prothymosin PF03247.9 EWM25406.1 - 7.1 6.8 30.7 3.6 7.7 11.5 2.3 2 0 0 2 2 2 0 Prothymosin/parathymosin family Sigma70_ner PF04546.8 EWM25406.1 - 9.8 5.7 17.9 1.2 8.7 3.3 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region Peptidase_C1 PF00112.18 EWM25407.1 - 3.3e-56 190.6 0.0 4.8e-56 190.0 0.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EWM25407.1 - 4.2e-11 42.9 0.1 6.9e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 EWM25407.1 - 2.9e-06 26.0 0.2 0.00027 19.5 0.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family zf-C2H2_3 PF13878.1 EWM25407.1 - 0.14 11.7 0.1 0.37 10.4 0.0 1.7 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO UL73_N PF12522.3 EWM25407.1 - 0.22 11.0 1.6 0.44 10.1 1.1 1.5 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal Caps_synth_CapC PF14102.1 EWM25408.1 - 0.095 12.8 0.7 0.14 12.2 0.5 1.3 1 0 0 1 1 1 0 Capsule biosynthesis CapC Peptidase_S10 PF00450.17 EWM25409.1 - 3.7e-106 355.7 0.0 4.3e-106 355.5 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase GST_N_3 PF13417.1 EWM25410.1 - 9.9e-12 44.9 0.1 2.2e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 EWM25410.1 - 2.4e-09 37.0 0.9 5.5e-09 35.8 0.6 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_C_3 PF14497.1 EWM25410.1 - 3.4e-08 33.8 0.1 6.7e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EWM25410.1 - 0.00068 19.4 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EWM25410.1 - 0.001 19.0 0.0 0.0022 17.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EWM25410.1 - 0.017 15.0 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain UCR_Fe-S_N PF10399.4 EWM25410.1 - 2.8 7.1 8.0 0.34 10.1 0.6 2.8 3 0 0 3 3 3 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal PIG-L PF02585.12 EWM25411.1 - 3e-23 82.7 0.0 6.2e-23 81.6 0.0 1.5 2 0 0 2 2 2 1 GlcNAc-PI de-N-acetylase Methyltransf_31 PF13847.1 EWM25412.1 - 1.4e-13 50.7 0.1 2.4e-13 49.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM25412.1 - 8.9e-12 45.5 0.1 2.9e-11 43.9 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EWM25412.1 - 5.6e-11 42.1 0.0 8.2e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 EWM25412.1 - 2.9e-10 40.4 0.1 1.8e-09 37.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM25412.1 - 4.8e-10 39.4 0.0 2.4e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.6 EWM25412.1 - 2.8e-08 32.8 0.0 3.8e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PRMT5 PF05185.11 EWM25412.1 - 2.8e-07 29.8 0.0 3.5e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase CMAS PF02353.15 EWM25412.1 - 4.2e-07 29.3 0.0 5.6e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EWM25412.1 - 1.6e-06 27.8 0.0 2.7e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EWM25412.1 - 3.7e-06 26.4 0.1 6e-06 25.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EWM25412.1 - 4.3e-06 27.0 0.1 1.5e-05 25.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM25412.1 - 3.8e-05 24.0 0.0 7.7e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EWM25412.1 - 0.00094 19.2 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 EWM25412.1 - 0.0019 17.6 0.1 0.0035 16.8 0.1 1.4 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.14 EWM25412.1 - 0.0031 17.0 0.1 0.0052 16.3 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 EWM25412.1 - 0.0032 16.6 0.0 0.0051 15.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 EWM25412.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 EWM25412.1 - 0.049 12.8 0.2 0.13 11.4 0.2 1.7 1 1 0 1 1 1 0 Tellurite resistance protein TehB UPF0020 PF01170.13 EWM25412.1 - 0.056 13.0 0.2 0.098 12.2 0.1 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_24 PF13578.1 EWM25412.1 - 0.12 13.2 0.0 0.32 11.8 0.0 1.9 1 1 1 2 2 2 0 Methyltransferase domain Pro_isomerase PF00160.16 EWM25413.1 - 8.5e-45 152.7 0.1 1e-44 152.5 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thr_synth_N PF14821.1 EWM25414.1 - 8.2e-26 89.8 0.0 2e-25 88.6 0.0 1.7 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 EWM25414.1 - 5.4e-21 75.1 0.0 7.4e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TMEM247 PF15444.1 EWM25415.1 - 0.031 14.0 0.9 0.032 14.0 0.6 1.1 1 0 0 1 1 1 0 Transmembrane protein 247 PHD PF00628.24 EWM25416.1 - 1.2e-25 88.9 36.5 1.1e-10 41.0 3.6 3.3 3 0 0 3 3 3 3 PHD-finger PHD_2 PF13831.1 EWM25416.1 - 4.2e-11 41.9 20.3 0.00033 19.9 1.7 3.7 3 0 0 3 3 3 3 PHD-finger 2OG-FeII_Oxy_3 PF13640.1 EWM25416.1 - 0.0026 18.2 0.0 0.0056 17.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EWM25416.1 - 0.0072 15.9 0.0 0.021 14.4 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-PHD-like PF15446.1 EWM25416.1 - 0.0085 15.3 24.2 0.081 12.2 2.0 3.5 3 0 0 3 3 3 3 PHD/FYVE-zinc-finger like domain DZR PF12773.2 EWM25416.1 - 0.019 14.7 8.7 0.019 14.7 6.0 4.1 2 1 2 4 4 4 0 Double zinc ribbon Prok-RING_1 PF14446.1 EWM25416.1 - 0.29 10.9 30.6 0.8 9.4 1.6 4.0 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 RRM_6 PF14259.1 EWM25417.1 - 1.3e-09 37.9 0.0 2.2e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EWM25417.1 - 1.4e-08 34.2 0.0 2.6e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1922 PF09082.5 EWM25417.1 - 0.001 19.0 0.3 1.7 8.8 0.1 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF1922) RRM_5 PF13893.1 EWM25417.1 - 0.029 14.2 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Opi1 PF08618.5 EWM25417.1 - 4.6 6.0 8.9 1.2 7.9 3.2 1.9 2 0 0 2 2 2 0 Transcription factor Opi1 EMP70 PF02990.11 EWM25418.1 - 1.7e-134 449.1 15.8 2.2e-134 448.7 11.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 GP41 PF00517.12 EWM25418.1 - 0.089 12.3 0.2 0.089 12.3 0.1 2.6 2 0 0 2 2 2 0 Retroviral envelope protein FancD2 PF14631.1 EWM25419.1 - 0.0027 14.8 2.2 0.0049 14.0 0.2 1.9 2 0 0 2 2 2 2 Fanconi anaemia protein FancD2 nuclease Mito_carr PF00153.22 EWM25420.1 - 1.4e-44 149.6 0.1 2.1e-19 68.9 0.0 4.2 2 2 1 3 3 3 3 Mitochondrial carrier protein TAT_signal PF10518.4 EWM25420.1 - 0.94 9.6 0.0 0.94 9.6 0.0 3.7 3 0 0 3 3 3 0 TAT (twin-arginine translocation) pathway signal sequence Colipase-like PF15083.1 EWM25421.1 - 2.2 8.2 9.2 5.8 6.9 6.4 1.6 1 1 0 1 1 1 0 Colipase-like PsbP PF01789.11 EWM25422.1 - 9.1e-13 48.0 0.0 1.2e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 PsbP Codanin-1_C PF15296.1 EWM25423.1 - 0.38 10.6 1.8 0.6 9.9 1.3 1.4 1 1 0 1 1 1 0 Codanin-1 C-terminus Pex2_Pex12 PF04757.9 EWM25424.1 - 1.8e-29 102.7 0.0 2.5e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 EWM25424.1 - 6.5e-06 25.8 9.8 1e-05 25.2 6.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EWM25424.1 - 8e-06 25.4 9.6 1.2e-05 24.9 6.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EWM25424.1 - 6.2e-05 22.5 9.7 9.6e-05 21.9 6.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EWM25424.1 - 8.4e-05 22.5 10.5 0.00013 21.8 7.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EWM25424.1 - 0.00014 21.4 6.5 0.00023 20.7 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EWM25424.1 - 0.00079 19.1 2.1 0.0014 18.2 1.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EWM25424.1 - 0.012 15.4 11.7 0.012 15.4 8.1 1.7 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Tcp11 PF05794.8 EWM25426.1 - 8.3e-49 166.4 0.0 1.4e-48 165.7 0.0 1.3 1 0 0 1 1 1 1 T-complex protein 11 PIG-L PF02585.12 EWM25426.1 - 0.12 12.9 0.0 1 9.8 0.0 2.3 2 0 0 2 2 2 0 GlcNAc-PI de-N-acetylase DEAD PF00270.24 EWM25427.1 - 1.4e-18 66.9 0.0 1.3e-17 63.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EWM25427.1 - 2.8e-15 55.9 0.0 1.6e-14 53.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EWM25427.1 - 0.00022 21.1 0.0 0.00094 19.0 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Hydrolase PF00702.21 EWM25428.1 - 3.3e-22 79.9 0.1 4.4e-11 43.6 0.0 3.2 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EWM25428.1 - 3.8e-18 66.3 0.0 1.3e-17 64.5 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EWM25428.1 - 2.2e-17 62.8 0.0 4.1e-11 42.3 0.0 3.3 2 1 0 2 2 2 2 E1-E2 ATPase Hydrolase_like2 PF13246.1 EWM25428.1 - 0.00018 21.4 0.0 0.00041 20.2 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EWM25428.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase p450 PF00067.17 EWM25429.1 - 5.5e-78 262.5 0.0 7.8e-78 262.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 EWM25429.1 - 4.9e-47 160.1 0.0 8.4e-47 159.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EWM25429.1 - 1.8e-21 76.7 0.0 4.2e-21 75.5 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_1 PF00258.20 EWM25429.1 - 1.7e-18 66.9 0.0 3.8e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.2 EWM25429.1 - 0.049 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain DUF4149 PF13664.1 EWM25431.1 - 1.5e-18 66.7 7.3 1.5e-18 66.7 5.1 2.4 4 0 0 4 4 4 1 Domain of unknown function (DUF4149) FAST_1 PF06743.10 EWM25432.1 - 0.062 13.0 0.4 13 5.5 0.0 3.8 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 1 COesterase PF00135.23 EWM25433.1 - 5.4e-85 286.1 0.0 3.1e-77 260.5 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EWM25433.1 - 2.4e-07 30.5 0.2 1.6e-06 27.8 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EWM25433.1 - 0.0014 18.3 0.7 0.0059 16.3 0.1 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Pkinase PF00069.20 EWM25434.1 - 1e-61 208.3 0.0 1.3e-61 208.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM25434.1 - 2.4e-28 98.9 0.0 3.2e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EWM25434.1 - 0.0029 17.4 0.6 0.27 10.9 0.0 2.2 1 1 0 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EWM25434.1 - 0.051 12.5 0.0 0.078 11.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 EWM25434.1 - 0.17 10.9 0.0 0.33 9.9 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Chorismate_bind PF00425.13 EWM25435.1 - 5.6e-63 212.6 0.0 7.7e-63 212.2 0.0 1.1 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 EWM25435.1 - 3.4e-40 137.5 0.0 5.1e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 EWM25435.1 - 1.5e-12 47.7 0.0 1e-10 41.7 0.0 3.0 2 2 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 EWM25435.1 - 2.6e-12 46.6 0.0 4.1e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase C26 Response_reg PF00072.19 EWM25435.1 - 0.00045 20.2 0.0 0.00087 19.2 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain MAT1 PF06391.8 EWM25436.1 - 0.0097 15.5 1.3 0.019 14.5 0.9 1.4 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 VTC PF09359.5 EWM25437.1 - 7.1e-75 251.6 0.0 9.9e-75 251.1 0.0 1.2 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EWM25437.1 - 2.8e-30 106.0 0.0 1.4e-19 70.9 0.0 2.4 1 1 1 2 2 2 2 SPX domain DUF202 PF02656.10 EWM25437.1 - 2.2e-10 40.6 0.3 4.2e-10 39.6 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) TauE PF01925.14 EWM25437.1 - 0.077 12.4 0.3 0.12 11.8 0.2 1.2 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE Ferritin PF00210.19 EWM25437.1 - 0.14 11.8 0.1 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Ferritin-like domain Pkinase_Tyr PF07714.12 EWM25438.1 - 3.9e-56 189.9 0.0 5.1e-56 189.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EWM25438.1 - 4.8e-54 183.2 0.0 7.1e-54 182.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 EWM25438.1 - 2e-07 30.2 0.0 3.7e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EWM25438.1 - 4.8e-06 25.7 0.1 2.7e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family EGF_2 PF07974.8 EWM25438.1 - 1.1e-05 25.4 6.8 1.1e-05 25.4 4.7 10.5 7 2 2 9 9 9 5 EGF-like domain APH PF01636.18 EWM25438.1 - 0.00066 19.4 0.0 0.0032 17.2 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Laminin_EGF PF00053.19 EWM25438.1 - 0.0057 16.5 9.4 0.0057 16.5 6.5 6.8 5 1 1 6 6 6 3 Laminin EGF-like (Domains III and V) hEGF PF12661.2 EWM25438.1 - 0.016 15.2 64.9 0.78 9.9 0.3 10.2 10 0 0 10 10 10 0 Human growth factor-like EGF CcmD PF04995.9 EWM25438.1 - 0.22 11.3 2.0 0.7 9.6 0.1 2.4 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Seadorna_VP7 PF07387.6 EWM25438.1 - 0.29 9.9 0.0 0.45 9.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 WD40 PF00400.27 EWM25440.1 - 1.4e-30 103.9 12.9 1.2e-07 31.3 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Sof1 PF04158.9 EWM25440.1 - 1.5e-14 53.8 3.0 2.6e-14 53.0 2.0 1.4 1 0 0 1 1 1 1 Sof1-like domain eIF2A PF08662.6 EWM25440.1 - 0.00018 21.3 0.0 0.044 13.5 0.0 2.6 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A CLP_protease PF00574.18 EWM25441.1 - 5.5e-78 260.8 0.7 7.2e-78 260.4 0.5 1.1 1 0 0 1 1 1 1 Clp protease Peptidase_S49 PF01343.13 EWM25441.1 - 0.057 13.1 0.0 0.096 12.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S49 Mito_carr PF00153.22 EWM25443.1 - 1e-66 220.7 1.5 1.1e-22 79.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein SAYSvFN PF10260.4 EWM25444.1 - 7.8e-12 44.8 0.0 1.2e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved domain (SAYSvFN) Sporozoite_P67 PF05642.6 EWM25444.1 - 6.8 4.4 5.9 8.5 4.0 4.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen tRNA_U5-meth_tr PF05958.6 EWM25445.1 - 8.5e-21 74.0 0.0 7.4e-20 70.9 0.0 1.9 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 EWM25445.1 - 1.1e-07 31.5 0.1 2e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM25445.1 - 5.6e-05 23.1 0.3 0.00026 20.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EWM25445.1 - 0.00081 18.5 0.0 0.0027 16.8 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.5 EWM25445.1 - 0.0012 18.4 0.1 0.0022 17.5 0.1 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 EWM25445.1 - 0.0066 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 EWM25445.1 - 0.052 14.0 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain TPMT PF05724.6 EWM25445.1 - 0.068 12.6 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MFS_1 PF07690.11 EWM25447.1 - 2.2e-17 62.8 34.2 7.2e-17 61.1 19.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MerE PF05052.7 EWM25447.1 - 0.23 11.4 6.3 0.045 13.7 1.2 2.1 2 0 0 2 2 2 0 MerE protein Dynamin_N PF00350.18 EWM25448.1 - 1.8e-18 66.8 0.0 9.3e-17 61.3 0.0 2.2 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EWM25448.1 - 6.1e-10 39.0 0.0 2.5e-09 37.1 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EWM25448.1 - 0.00012 22.5 0.0 0.0056 17.1 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein FeoB_N PF02421.13 EWM25448.1 - 0.0032 16.7 0.1 0.098 11.9 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 EWM25448.1 - 0.0034 16.5 0.0 0.011 14.9 0.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EWM25448.1 - 0.005 16.2 0.1 0.65 9.3 0.0 2.2 2 0 0 2 2 2 2 Ras family GTP_EFTU PF00009.22 EWM25448.1 - 0.053 12.9 0.0 0.29 10.5 0.0 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain UPF0079 PF02367.12 EWM25448.1 - 0.069 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 G6PD_C PF02781.11 EWM25449.1 - 6.5e-30 103.9 0.0 3.8e-22 78.5 0.0 2.3 2 1 0 2 2 2 2 Glucose-6-phosphate dehydrogenase, C-terminal domain UPF0020 PF01170.13 EWM25450.1 - 0.00093 18.8 0.1 0.0016 18.0 0.1 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 WD40 PF00400.27 EWM25452.1 - 6.8e-22 76.4 15.8 8.9e-06 25.3 0.2 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat WW PF00397.21 EWM25452.1 - 6.1e-11 41.9 2.1 1.3e-10 40.8 1.4 1.6 1 0 0 1 1 1 1 WW domain Sec16_C PF12931.2 EWM25452.1 - 4.6e-07 29.8 0.2 9.9e-07 28.7 0.1 1.6 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 WD40 PF00400.27 EWM25454.1 - 6.4e-28 95.5 10.1 1.2e-05 25.0 0.0 6.4 6 1 0 6 6 6 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EWM25454.1 - 0.0074 14.6 0.2 0.77 7.9 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.3 EWM25454.1 - 0.6 8.1 3.4 0.48 8.4 0.2 2.4 2 2 0 3 3 3 0 Nucleoporin Nup120/160 adh_short PF00106.20 EWM25456.1 - 2.8e-29 102.1 1.4 2.8e-29 102.1 1.0 2.1 3 0 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.1 EWM25456.1 - 8.2e-21 74.8 0.0 1e-15 58.2 0.0 2.7 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EWM25456.1 - 1.4e-17 63.9 0.9 3.4e-17 62.6 0.2 2.0 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 EWM25456.1 - 0.0027 17.4 0.6 0.0027 17.4 0.4 1.9 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase CBS PF00571.23 EWM25457.1 - 5.6e-20 70.8 0.2 6.6e-12 45.0 0.2 2.5 2 0 0 2 2 2 2 CBS domain SpoIIE PF07228.7 EWM25457.1 - 9.4e-11 41.7 0.0 8.5e-10 38.6 0.0 2.4 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EWM25457.1 - 9e-06 25.2 0.2 0.00018 20.9 0.2 2.4 1 1 0 1 1 1 1 Protein phosphatase 2C Abhydrolase_5 PF12695.2 EWM25459.1 - 6.3e-21 74.6 0.1 9.4e-21 74.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EWM25459.1 - 4.6e-16 59.3 1.5 1e-15 58.2 1.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EWM25459.1 - 6.9e-08 32.3 0.1 1.2e-06 28.2 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold zf-RanBP PF00641.13 EWM25459.1 - 1e-05 24.5 1.8 2.1e-05 23.5 1.3 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Peptidase_S15 PF02129.13 EWM25459.1 - 1.1e-05 24.9 0.0 1.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 EWM25459.1 - 2.7e-05 23.4 0.0 0.00028 20.1 0.0 2.3 2 1 0 2 2 2 1 Prolyl oligopeptidase family PhoPQ_related PF10142.4 EWM25459.1 - 0.00042 18.9 0.0 0.0006 18.4 0.0 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein FSH1 PF03959.8 EWM25459.1 - 0.0077 15.6 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) FBPase PF00316.15 EWM25460.1 - 2.5e-102 342.0 0.2 3e-101 338.4 0.1 2.2 1 1 0 1 1 1 1 Fructose-1-6-bisphosphatase DUF4001 PF13165.1 EWM25460.1 - 0.24 11.0 4.4 0.66 9.6 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4001) Eapp_C PF10238.4 EWM25461.1 - 1e-08 35.1 0.2 1.2e-07 31.7 0.2 2.2 1 1 0 1 1 1 1 E2F-associated phosphoprotein Yippee-Mis18 PF03226.9 EWM25461.1 - 0.087 12.8 0.1 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly eIF-1a PF01176.14 EWM25462.1 - 2.2e-18 65.4 0.2 3.2e-18 64.9 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 tRNA_anti-codon PF01336.20 EWM25462.1 - 0.19 11.5 0.9 0.36 10.7 0.0 1.9 3 0 0 3 3 3 0 OB-fold nucleic acid binding domain Tim44 PF04280.10 EWM25463.1 - 0.075 13.0 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Tim44-like domain Histone PF00125.19 EWM25465.1 - 3.2e-19 68.8 0.0 4.3e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.8 EWM25465.1 - 0.00081 19.6 0.0 0.0013 18.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TraH PF06122.6 EWM25465.1 - 0.0035 16.2 0.1 0.0036 16.1 0.1 1.0 1 0 0 1 1 1 1 Conjugative relaxosome accessory transposon protein CBFD_NFYB_HMF PF00808.18 EWM25465.1 - 0.025 14.6 0.0 0.056 13.4 0.0 1.6 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Peptidase_M17 PF00883.16 EWM25466.1 - 2.1e-85 286.3 0.0 4.7e-85 285.1 0.0 1.5 2 0 0 2 2 2 1 Cytosol aminopeptidase family, catalytic domain Thioredoxin PF00085.15 EWM25468.1 - 4.3e-10 39.1 0.0 1e-07 31.5 0.0 3.4 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_6 PF13848.1 EWM25468.1 - 1e-05 25.4 0.0 0.0032 17.2 0.0 3.6 3 1 0 4 4 4 1 Thioredoxin-like domain DUF836 PF05768.9 EWM25468.1 - 0.0039 17.4 0.0 0.011 15.9 0.0 1.8 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_8 PF13905.1 EWM25468.1 - 0.042 13.9 0.0 0.48 10.5 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_2 PF13098.1 EWM25468.1 - 0.072 13.2 0.0 2.9 8.1 0.0 3.0 2 1 0 2 2 2 0 Thioredoxin-like domain SecA_DEAD PF07517.9 EWM25469.1 - 2.7e-99 331.7 1.2 4.3e-99 331.1 0.0 1.8 2 0 0 2 2 2 1 SecA DEAD-like domain SecA_SW PF07516.8 EWM25469.1 - 8.1e-38 130.3 8.1 8.1e-38 130.3 5.6 1.6 2 0 0 2 2 2 1 SecA Wing and Scaffold domain SecA_PP_bind PF01043.15 EWM25469.1 - 3.6e-30 104.6 0.3 1.7e-29 102.5 0.0 2.3 2 0 0 2 2 2 1 SecA preprotein cross-linking domain DEAD PF00270.24 EWM25469.1 - 0.00038 20.0 0.1 0.0026 17.2 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AF0941-like PF14591.1 EWM25469.1 - 0.012 15.6 4.0 0.3 11.1 0.0 2.9 2 0 0 2 2 2 0 AF0941-like ResIII PF04851.10 EWM25469.1 - 0.077 12.8 1.1 0.44 10.3 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EWM25469.1 - 0.27 11.0 3.0 5.1 7.0 0.0 3.0 3 0 0 3 3 3 0 Helicase conserved C-terminal domain DUF1104 PF06518.6 EWM25469.1 - 0.28 11.3 7.5 0.74 9.9 2.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) DBI_PRT PF02277.12 EWM25471.1 - 9.3e-85 284.5 6.7 1.8e-53 181.7 3.6 2.1 1 1 1 2 2 2 2 Phosphoribosyltransferase KdpC PF02669.10 EWM25471.1 - 0.059 13.0 0.5 0.1 12.2 0.4 1.3 1 0 0 1 1 1 0 K+-transporting ATPase, c chain FAD_binding_3 PF01494.14 EWM25472.1 - 3.6e-11 42.7 0.3 1e-05 24.7 0.1 2.7 2 1 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.9 EWM25472.1 - 9.9e-06 24.4 0.0 0.12 10.9 0.0 2.8 2 1 0 2 2 2 2 Tryptophan halogenase DAO PF01266.19 EWM25472.1 - 4e-05 22.6 0.5 0.0021 17.0 0.0 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EWM25472.1 - 8.2e-05 21.8 0.1 0.0006 18.9 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 EWM25472.1 - 0.00012 22.0 1.3 0.00016 21.5 0.5 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EWM25472.1 - 0.00039 20.3 0.0 0.0013 18.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EWM25472.1 - 0.00083 19.1 0.0 0.46 10.2 0.0 2.6 3 0 0 3 3 3 2 FAD-NAD(P)-binding HI0933_like PF03486.9 EWM25472.1 - 0.012 14.0 0.0 0.019 13.4 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 EWM25472.1 - 0.016 14.1 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 EWM25472.1 - 0.027 13.5 0.0 0.051 12.6 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EWM25472.1 - 0.029 13.2 0.1 0.14 11.0 0.0 2.0 2 1 0 2 2 2 0 Lycopene cyclase protein MiaE_2 PF13794.1 EWM25472.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like UQ_con PF00179.21 EWM25474.1 - 3.3e-26 91.3 0.0 5.9e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EWM25474.1 - 0.039 13.8 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 RWD domain CobS PF02654.10 EWM25475.1 - 2.1e-19 70.0 12.2 7.5e-18 64.9 8.4 2.1 1 1 0 1 1 1 1 Cobalamin-5-phosphate synthase DnaJ PF00226.26 EWM25476.1 - 5.3e-18 64.5 0.0 1e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain OppC_N PF12911.2 EWM25476.1 - 0.065 12.6 0.7 0.27 10.6 0.2 2.0 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Wax2_C PF12076.3 EWM25476.1 - 0.13 11.9 0.7 0.48 10.1 0.1 1.9 2 0 0 2 2 2 0 WAX2 C-terminal domain WHG PF13305.1 EWM25477.1 - 0.052 14.1 0.0 0.2 12.2 0.0 2.0 1 0 0 1 1 1 0 WHG domain TFCD_C PF12612.3 EWM25478.1 - 7.2e-33 113.6 0.6 3.7e-32 111.3 0.0 2.6 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 EWM25478.1 - 0.00026 20.8 29.7 0.078 13.0 0.0 10.8 11 0 0 11 11 11 2 HEAT repeat HEAT_2 PF13646.1 EWM25478.1 - 0.0014 18.8 28.4 0.11 12.8 0.1 8.0 5 2 3 9 9 9 4 HEAT repeats HEAT_EZ PF13513.1 EWM25478.1 - 0.0039 17.6 47.5 0.0095 16.4 0.0 10.3 9 2 2 11 11 11 3 HEAT-like repeat RtcB PF01139.12 EWM25480.1 - 1.9e-142 475.1 0.3 2.3e-142 474.9 0.2 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB SWIB PF02201.13 EWM25482.1 - 4.6e-47 157.5 0.0 2.9e-22 78.1 0.0 2.4 2 0 0 2 2 2 2 SWIB/MDM2 domain DEK_C PF08766.6 EWM25482.1 - 1.2e-12 47.3 0.5 3.3e-12 45.9 0.4 1.7 2 0 0 2 2 2 1 DEK C terminal domain Peptidase_M18 PF02127.10 EWM25484.1 - 2e-111 372.5 0.0 3.1e-111 371.9 0.0 1.2 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) PDZ PF00595.19 EWM25485.1 - 6.2e-05 23.1 0.0 0.0002 21.4 0.0 1.8 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EWM25485.1 - 0.0084 15.9 0.0 0.026 14.3 0.0 1.7 2 0 0 2 2 2 1 PDZ domain DUF3006 PF11213.3 EWM25485.1 - 0.03 14.0 0.0 0.091 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) NPV_P10 PF05531.7 EWM25486.1 - 0.006 16.8 8.9 2.1 8.6 0.2 4.6 4 1 1 5 5 5 2 Nucleopolyhedrovirus P10 protein DPM3 PF08285.6 EWM25486.1 - 0.35 10.7 4.2 15 5.5 0.2 3.4 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF1664 PF07889.7 EWM25486.1 - 1.6 8.5 19.4 0.03 14.1 1.5 3.5 3 1 0 4 4 4 0 Protein of unknown function (DUF1664) BMP2K_C PF15282.1 EWM25486.1 - 2.4 8.2 7.7 56 3.7 5.3 2.7 1 1 0 1 1 1 0 BMP-2-inducible protein kinase C-terminus DUF842 PF05811.8 EWM25486.1 - 4.5 6.7 8.1 2.7 7.4 2.8 2.7 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF842) Toxin_39 PF15500.1 EWM25486.1 - 8 6.6 9.9 6.6 6.9 0.9 3.6 1 1 2 3 3 3 0 Putative RNase-like toxin RRM_6 PF14259.1 EWM25487.1 - 4.3e-18 65.0 0.1 1e-09 38.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) La PF05383.12 EWM25487.1 - 1.9e-15 56.4 0.0 3.5e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 EWM25487.1 - 1.1e-13 50.5 0.5 1.9e-07 30.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EWM25487.1 - 5.4e-11 42.2 0.4 5.5e-07 29.3 0.1 2.6 2 0 0 2 2 2 2 RNA binding motif RRM_5 PF13893.1 EWM25487.1 - 1.3e-08 34.5 0.0 0.0034 17.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SRP-alpha_N PF04086.8 EWM25487.1 - 7.4 5.8 7.4 16 4.7 5.1 1.5 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Microcin PF03526.8 EWM25488.1 - 0.12 11.9 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Colicin E1 (microcin) immunity protein Myb_DNA-binding PF00249.26 EWM25490.1 - 2.2e-27 94.8 0.6 2.2e-12 46.8 0.3 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EWM25490.1 - 2.7e-19 69.0 1.7 6.9e-15 54.8 0.0 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EWM25490.1 - 0.005 16.9 0.0 0.026 14.6 0.0 2.3 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain SNF2_N PF00176.18 EWM25491.1 - 6.7e-65 218.8 0.1 3.7e-31 108.0 0.0 2.7 2 1 0 2 2 2 2 SNF2 family N-terminal domain zf-PARP PF00645.13 EWM25491.1 - 1.9e-13 50.4 0.9 1.1e-12 47.9 0.0 2.5 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Helicase_C PF00271.26 EWM25491.1 - 1.3e-11 44.2 0.0 3.4e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_4 PF15227.1 EWM25491.1 - 0.0016 18.2 9.8 0.0062 16.3 6.8 2.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Rep_fac-A_C PF08646.5 EWM25491.1 - 0.87 9.2 4.3 7.2 6.3 0.0 2.7 2 0 0 2 2 2 0 Replication factor-A C terminal domain FYVE PF01363.16 EWM25492.1 - 5.9e-13 48.5 1.5 1.3e-12 47.4 1.0 1.5 1 0 0 1 1 1 1 FYVE zinc finger Synaptobrevin PF00957.16 EWM25492.1 - 6.7e-06 25.6 0.1 1.3e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 Synaptobrevin FYVE_2 PF02318.11 EWM25492.1 - 5.5e-05 23.0 1.0 0.00013 21.8 0.7 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger Cullin PF00888.17 EWM25493.1 - 4e-140 468.1 0.0 6.9e-140 467.3 0.0 1.4 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EWM25493.1 - 8.7e-23 79.9 0.2 2.3e-22 78.6 0.1 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain Pkinase PF00069.20 EWM25494.1 - 5.8e-48 163.2 0.0 9e-46 156.1 0.0 2.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM25494.1 - 1.8e-27 96.0 0.0 2e-18 66.4 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 EWM25494.1 - 0.0047 16.6 3.0 0.8 9.3 0.1 3.1 2 2 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EWM25494.1 - 0.0075 15.2 0.1 0.046 12.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like CTP_transf_2 PF01467.21 EWM25495.1 - 1.7e-17 63.9 0.0 6.4e-16 58.7 0.0 2.1 1 1 0 1 1 1 1 Cytidylyltransferase LMBR1 PF04791.11 EWM25498.1 - 1.4e-36 126.1 9.1 4.1e-36 124.5 6.3 1.6 1 1 0 1 1 1 1 LMBR1-like membrane protein PT PF04886.7 EWM25499.1 - 0.0012 18.0 18.5 0.0012 18.0 12.9 4.4 4 1 0 4 4 4 1 PT repeat TFIIA PF03153.8 EWM25499.1 - 8.8 6.1 9.7 13 5.5 6.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_L4 PF00573.17 EWM25502.1 - 1.9e-40 138.2 0.1 1.9e-40 138.2 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EWM25502.1 - 1.1e-25 89.3 2.5 1.1e-25 89.3 1.7 1.9 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain FAD-oxidase_C PF02913.14 EWM25503.1 - 5.7e-55 186.3 0.1 7.4e-55 185.9 0.1 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EWM25503.1 - 4.2e-36 123.4 3.5 2.3e-35 121.0 0.2 2.5 2 0 0 2 2 2 1 FAD binding domain 2-oxoacid_dh PF00198.18 EWM25504.1 - 1.8e-67 227.0 0.0 2.6e-67 226.4 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EWM25504.1 - 1e-18 66.7 0.8 2.2e-18 65.6 0.1 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 EWM25504.1 - 2.4e-15 55.8 0.4 7.8e-15 54.2 0.3 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EWM25504.1 - 0.015 14.9 0.8 0.47 10.1 0.1 2.6 2 0 0 2 2 2 0 Biotin-lipoyl like DUF3407 PF11887.3 EWM25505.1 - 0.03 13.6 1.0 0.043 13.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3407) Ribosomal_S3Ae PF01015.13 EWM25506.1 - 8.9e-73 243.7 3.1 1e-72 243.5 2.2 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family SpoVIF PF14069.1 EWM25506.1 - 0.089 12.5 0.9 0.23 11.2 0.3 1.9 2 0 0 2 2 2 0 Stage VI sporulation protein F FSH1 PF03959.8 EWM25507.1 - 8e-37 126.7 0.0 1.3e-36 126.0 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EWM25507.1 - 1e-05 25.3 0.0 1.5e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EWM25507.1 - 2e-05 24.6 0.8 0.16 11.8 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family CoA_transf_3 PF02515.12 EWM25507.1 - 0.004 16.4 0.1 0.0058 15.8 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III LIP PF03583.9 EWM25507.1 - 0.0067 15.6 0.0 0.027 13.6 0.0 1.7 2 0 0 2 2 2 1 Secretory lipase Methyltransf_26 PF13659.1 EWM25507.1 - 0.061 13.3 0.0 0.12 12.3 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain ubiquitin PF00240.18 EWM25509.1 - 8.5e-08 31.4 0.0 2.6e-05 23.5 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin family zf-met PF12874.2 EWM25510.1 - 2e-06 27.8 1.4 4.6e-06 26.6 1.0 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type SURF2 PF05477.6 EWM25510.1 - 0.049 12.7 0.6 0.071 12.2 0.4 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) PRP4 PF08799.6 EWM25510.1 - 8.9 5.6 7.2 0.41 9.9 0.7 2.0 2 0 0 2 2 2 0 pre-mRNA processing factor 4 (PRP4) like Coatomer_WDAD PF04053.9 EWM25511.1 - 1.3e-149 498.7 0.0 3.1e-149 497.5 0.0 1.6 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 EWM25511.1 - 4.9e-48 159.3 0.6 6.8e-12 44.7 0.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat DLH PF01738.13 EWM25513.1 - 2.3e-22 79.3 0.0 2.6e-22 79.1 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.2 EWM25513.1 - 0.00025 21.0 0.1 0.00034 20.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM25513.1 - 0.00032 20.4 0.0 0.00042 20.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Pkinase PF00069.20 EWM25514.1 - 3.6e-10 39.4 0.0 4e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain zf-RING_2 PF13639.1 EWM25515.1 - 2e-11 43.5 10.3 2e-11 43.5 7.1 1.9 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EWM25515.1 - 3.6e-07 30.2 4.2 8.1e-07 29.0 2.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EWM25515.1 - 1.2e-05 25.1 9.1 1.2e-05 25.1 6.3 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EWM25515.1 - 2.5e-05 23.8 5.9 7.4e-05 22.3 4.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EWM25515.1 - 0.00027 20.5 8.5 0.00066 19.2 5.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EWM25515.1 - 0.0051 16.5 8.5 0.01 15.5 5.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.3 EWM25515.1 - 0.18 11.7 6.3 0.83 9.6 4.3 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 EWM25515.1 - 2.1 8.4 14.5 0.18 11.8 6.3 2.1 2 0 0 2 2 2 0 RING-variant domain PHD PF00628.24 EWM25515.1 - 3.8 7.2 10.8 1.6 8.4 5.3 2.1 2 0 0 2 2 2 0 PHD-finger zf-Apc11 PF12861.2 EWM25515.1 - 9.8 6.0 9.6 0.92 9.3 3.1 1.9 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Acetyltransf_1 PF00583.19 EWM25517.1 - 6.5e-18 64.5 0.0 1.5e-17 63.3 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EWM25517.1 - 3.7e-09 36.6 0.0 1.2e-08 35.0 0.0 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EWM25517.1 - 1e-08 35.2 0.0 1.5e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EWM25517.1 - 6.1e-07 29.7 0.0 1.1e-06 28.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EWM25517.1 - 1.2e-06 28.1 0.0 2.3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EWM25517.1 - 9.7e-05 22.1 0.0 0.0015 18.3 0.0 2.2 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 EWM25517.1 - 0.00016 21.6 0.0 0.00028 20.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PCP_red PF08369.5 EWM25517.1 - 0.00075 19.3 0.3 0.032 14.0 0.1 2.6 2 1 0 2 2 2 1 Proto-chlorophyllide reductase 57 kD subunit Acetyltransf_8 PF13523.1 EWM25517.1 - 0.0052 16.6 0.0 0.0079 16.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EWM25517.1 - 0.019 14.8 0.0 0.051 13.4 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain AAA_11 PF13086.1 EWM25518.1 - 6.2e-61 205.9 0.1 6.2e-61 205.9 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.1 EWM25518.1 - 1.1e-56 191.4 0.0 1.9e-56 190.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain SEN1_N PF12726.2 EWM25518.1 - 9.6e-12 43.7 0.0 2e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 SEN1 N terminal AAA_19 PF13245.1 EWM25518.1 - 3.3e-08 33.1 0.2 2.5e-07 30.3 0.1 2.5 3 0 0 3 3 3 1 Part of AAA domain Med26 PF08711.6 EWM25518.1 - 2.7e-06 26.7 0.3 6.2e-06 25.6 0.2 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Viral_helicase1 PF01443.13 EWM25518.1 - 6.7e-05 22.5 0.0 0.19 11.1 0.0 3.7 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EWM25518.1 - 7.7e-05 22.3 0.0 0.23 11.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EWM25518.1 - 0.0067 16.1 0.0 0.023 14.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 EWM25518.1 - 0.096 12.8 0.0 2 8.5 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MAPEG PF01124.13 EWM25519.1 - 2.1e-13 49.9 6.6 3.9e-13 49.1 4.6 1.5 1 1 1 2 2 2 1 MAPEG family TPR_2 PF07719.12 EWM25520.1 - 2.8e-25 86.1 24.8 0.00061 19.5 0.0 9.6 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_1 PF00515.23 EWM25520.1 - 2.3e-21 74.4 9.0 7.6e-05 22.1 0.0 8.4 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.1 EWM25520.1 - 5.1e-19 67.6 23.1 9.4e-07 28.3 0.1 7.3 3 1 1 7 7 7 4 TPR repeat TPR_12 PF13424.1 EWM25520.1 - 3.1e-17 62.2 1.9 5.6e-09 35.8 0.1 7.4 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.1 EWM25520.1 - 3.5e-15 54.5 9.9 3.6e-05 23.2 0.0 6.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 EWM25520.1 - 2.5e-12 47.1 36.3 3.8e-05 24.2 0.1 7.8 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 EWM25520.1 - 2.2e-09 36.4 0.0 0.07 12.9 0.0 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 EWM25520.1 - 2.7e-09 37.2 12.5 0.013 15.8 0.0 6.2 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EWM25520.1 - 4.8e-09 35.7 0.0 0.64 10.3 0.0 6.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EWM25520.1 - 1.2e-08 34.8 30.0 0.29 11.8 0.4 9.2 6 2 3 9 9 9 3 Tetratricopeptide repeat Apc3 PF12895.2 EWM25520.1 - 1.1e-06 28.6 3.2 0.0061 16.6 0.1 6.0 4 1 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EWM25520.1 - 0.0005 19.8 0.0 0.0005 19.8 0.0 7.4 7 1 1 8 8 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 EWM25520.1 - 0.011 16.1 15.9 2.6 8.7 0.0 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_9 PF13371.1 EWM25520.1 - 0.023 14.5 14.1 0.13 12.1 0.1 5.7 4 2 2 6 6 6 0 Tetratricopeptide repeat Glyoxalase PF00903.20 EWM25520.1 - 0.056 13.4 0.0 12 5.8 0.0 2.9 2 1 1 3 3 3 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TPR_4 PF07721.9 EWM25520.1 - 0.52 10.8 24.8 5.1 7.8 0.0 7.1 7 0 0 7 7 5 0 Tetratricopeptide repeat DUF4167 PF13763.1 EWM25520.1 - 8.1 6.5 7.8 12 6.0 0.1 2.9 3 0 0 3 3 2 0 Domain of unknown function (DUF4167) GCIP PF13324.1 EWM25521.1 - 8.7e-18 64.5 0.0 2.5e-17 62.9 0.0 1.7 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting Nop53 PF07767.6 EWM25521.1 - 0.36 9.7 4.0 0.56 9.1 2.8 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) ArgJ PF01960.13 EWM25522.1 - 3e-93 312.3 0.0 6.5e-93 311.2 0.0 1.5 1 1 0 1 1 1 1 ArgJ family SR-25 PF10500.4 EWM25522.1 - 0.24 10.8 6.2 0.38 10.1 4.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Glyoxalase_2 PF12681.2 EWM25524.1 - 9.8e-09 35.7 0.0 1.2e-08 35.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EWM25524.1 - 0.0071 16.3 0.0 0.025 14.5 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Kazal_2 PF07648.10 EWM25526.1 - 1.4e-20 72.8 44.6 3.1e-05 23.8 2.6 6.1 5 0 0 5 5 5 5 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 EWM25526.1 - 9.9e-20 70.3 57.0 5.3e-06 26.3 4.5 6.5 6 0 0 6 6 6 5 Kazal-type serine protease inhibitor domain Beta-Casp PF10996.3 EWM25527.1 - 2.1e-20 72.9 0.0 4.6e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain CPSF100_C PF13299.1 EWM25527.1 - 2.2e-07 31.1 0.0 4.4e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Lactamase_B PF00753.22 EWM25527.1 - 0.037 13.6 0.0 0.19 11.3 0.0 2.2 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Mpv17_PMP22 PF04117.7 EWM25529.1 - 5.6e-24 83.5 0.5 9e-24 82.8 0.3 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family zf-C3HC4_3 PF13920.1 EWM25530.1 - 4.4e-13 48.6 14.3 7.9e-13 47.8 9.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EWM25530.1 - 5.8e-07 29.4 16.9 9.8e-07 28.7 11.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EWM25530.1 - 4.1e-05 23.3 14.9 7.3e-05 22.5 10.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EWM25530.1 - 0.013 15.2 15.2 0.025 14.3 10.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.1 EWM25530.1 - 0.32 10.6 13.8 0.67 9.5 9.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TRAM_LAG1_CLN8 PF03798.11 EWM25533.1 - 0.012 15.1 23.3 0.022 14.2 16.2 1.8 1 1 0 1 1 1 0 TLC domain Apt1 PF10351.4 EWM25535.1 - 2e-11 43.4 0.0 4.9e-06 25.6 0.0 2.6 3 0 0 3 3 3 2 Golgi-body localisation protein domain BTK PF00779.14 EWM25535.1 - 9.2e-05 21.9 2.3 0.00019 20.9 1.6 1.5 1 0 0 1 1 1 1 BTK motif HIT PF01230.18 EWM25536.1 - 4e-23 81.7 0.3 6.6e-23 81.0 0.2 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EWM25536.1 - 7.2e-08 32.6 0.4 1.2e-07 31.9 0.2 1.4 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GTP_EFTU PF00009.22 EWM25537.1 - 3.8e-26 91.6 0.2 5e-20 71.7 0.1 2.9 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EWM25537.1 - 1.9e-17 63.0 0.0 3.9e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.18 EWM25537.1 - 1.4e-05 25.0 0.0 2.7e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 EWM25537.1 - 0.00095 19.2 1.8 0.5 10.5 0.0 3.7 3 1 0 3 3 3 1 Elongation factor Tu domain 2 Dynamin_N PF00350.18 EWM25537.1 - 0.0092 15.8 0.0 0.21 11.3 0.0 2.5 2 0 0 2 2 2 1 Dynamin family Miro PF08477.8 EWM25537.1 - 0.017 15.5 0.0 0.041 14.3 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein PduV-EutP PF10662.4 EWM25537.1 - 0.021 14.3 0.1 0.96 8.9 0.0 3.0 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU_D4 PF14578.1 EWM25537.1 - 0.033 13.8 0.1 0.12 12.0 0.1 2.0 1 0 0 1 1 1 0 Elongation factor Tu domain 4 IF2_N PF04760.10 EWM25537.1 - 0.056 13.1 0.0 0.27 10.9 0.0 2.3 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region Glyco_trans_1_2 PF13524.1 EWM25537.1 - 0.068 13.4 0.3 0.18 12.1 0.2 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 SRPRB PF09439.5 EWM25537.1 - 0.19 10.9 0.0 0.34 10.1 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit zf-RING_2 PF13639.1 EWM25539.1 - 1.2e-12 47.4 7.4 1.2e-12 47.4 5.2 1.9 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EWM25539.1 - 7.4e-08 32.3 1.6 1.6e-07 31.3 1.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EWM25539.1 - 0.00039 20.0 4.5 0.00039 20.0 3.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EWM25539.1 - 0.0016 18.4 7.4 0.0016 18.4 5.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EWM25539.1 - 0.002 17.8 6.1 0.002 17.8 4.2 1.9 3 0 0 3 3 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EWM25539.1 - 0.004 16.7 6.4 0.004 16.7 4.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EWM25539.1 - 0.013 15.3 2.1 0.013 15.3 1.5 1.8 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EWM25539.1 - 0.22 11.5 7.8 0.46 10.5 5.4 1.5 1 0 0 1 1 1 0 RING-variant domain SDA1 PF05285.7 EWM25539.1 - 0.25 10.6 14.3 0.37 10.0 9.9 1.2 1 0 0 1 1 1 0 SDA1 FANCL_C PF11793.3 EWM25539.1 - 0.65 9.9 4.4 1.5 8.8 3.0 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain CDC45 PF02724.9 EWM25539.1 - 0.98 7.3 6.7 1.7 6.5 4.6 1.3 1 0 0 1 1 1 0 CDC45-like protein Spore_coat_CotO PF14153.1 EWM25539.1 - 2.1 7.7 7.0 3.2 7.1 4.9 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Daxx PF03344.10 EWM25539.1 - 4.2 5.7 17.3 6.9 5.0 12.0 1.2 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 EWM25539.1 - 4.8 4.9 18.5 7 4.4 12.9 1.1 1 0 0 1 1 1 0 Nop14-like family SNF2_N PF00176.18 EWM25540.1 - 8.4e-30 103.5 0.0 1.1e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EWM25540.1 - 2.4e-07 30.3 0.0 3.3e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 EWM25540.1 - 0.0013 18.1 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.10 EWM25540.1 - 0.0015 18.3 0.0 0.0072 16.1 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA PF00004.24 EWM25540.1 - 0.0078 16.4 0.0 0.22 11.7 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 EWM25540.1 - 0.067 12.7 0.0 0.18 11.3 0.0 1.6 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.1 EWM25540.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain NUP50 PF08911.6 EWM25542.1 - 9.7e-10 38.6 1.7 3.3e-09 37.0 1.2 2.0 1 0 0 1 1 1 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.13 EWM25542.1 - 1.3e-05 25.2 0.0 2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain DUF605 PF04652.11 EWM25542.1 - 2.4 7.4 16.4 0.2 11.0 7.1 1.9 2 0 0 2 2 2 0 Vta1 like RRF PF01765.14 EWM25543.1 - 7.5e-47 158.8 0.0 9.4e-47 158.5 0.0 1.1 1 0 0 1 1 1 1 Ribosome recycling factor HNH PF01844.18 EWM25544.1 - 3.3e-08 33.2 0.1 3.3e-08 33.2 0.1 2.9 3 0 0 3 3 3 1 HNH endonuclease GAF_2 PF13185.1 EWM25546.1 - 0.035 14.6 0.2 1.5 9.3 0.0 3.2 2 1 1 3 3 3 0 GAF domain WBP-1 PF11669.3 EWM25546.1 - 0.12 12.5 4.0 0.23 11.5 0.0 2.7 2 0 0 2 2 2 0 WW domain-binding protein 1 zf-RING_2 PF13639.1 EWM25547.1 - 7.4e-16 57.7 5.5 1e-15 57.2 3.8 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EWM25547.1 - 6.5e-11 42.0 4.8 8.8e-11 41.6 3.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EWM25547.1 - 3.4e-09 36.6 5.0 7.6e-09 35.5 3.5 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EWM25547.1 - 5.6e-09 35.5 3.7 8.3e-09 34.9 2.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EWM25547.1 - 3.9e-08 32.8 3.3 5.6e-08 32.3 2.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EWM25547.1 - 1.1e-07 31.4 4.0 1.6e-07 30.9 2.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EWM25547.1 - 1.2e-05 25.0 0.2 1.6e-05 24.6 0.2 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Vps39_2 PF10367.4 EWM25547.1 - 1.5e-05 25.0 0.9 4.4e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-RING_UBOX PF13445.1 EWM25547.1 - 4e-05 23.2 2.1 0.0029 17.2 0.3 2.3 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.1 EWM25547.1 - 0.00017 21.0 1.7 0.00031 20.2 1.2 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 RINGv PF12906.2 EWM25547.1 - 0.00019 21.4 3.2 0.00037 20.4 2.2 1.5 1 1 0 1 1 1 1 RING-variant domain zf-RING_4 PF14570.1 EWM25547.1 - 0.00087 18.8 2.7 0.0012 18.3 1.9 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain PHD PF00628.24 EWM25547.1 - 0.0037 16.9 3.9 0.01 15.5 2.7 1.7 1 1 1 2 2 2 1 PHD-finger Prok-RING_1 PF14446.1 EWM25547.1 - 0.0044 16.7 3.3 0.039 13.6 0.7 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 Rtf2 PF04641.7 EWM25547.1 - 0.013 14.7 0.5 0.017 14.3 0.3 1.3 1 1 0 1 1 1 0 Rtf2 RING-finger NADH-G_4Fe-4S_3 PF10588.4 EWM25547.1 - 0.017 14.3 2.2 0.079 12.2 0.2 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Rad50_zn_hook PF04423.9 EWM25547.1 - 0.018 14.4 4.0 0.22 11.0 0.2 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-Nse PF11789.3 EWM25547.1 - 0.024 14.1 1.4 0.036 13.5 1.0 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.6 EWM25547.1 - 0.044 13.7 5.3 0.082 12.9 3.6 1.5 1 1 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.1 EWM25547.1 - 0.12 12.2 4.1 1.4 8.8 3.5 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EWM25547.1 - 0.14 12.1 5.4 1.2 9.1 3.7 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain PLATZ PF04640.9 EWM25547.1 - 0.2 11.9 0.8 6 7.1 0.2 2.1 1 1 1 2 2 2 0 PLATZ transcription factor C1_3 PF07649.7 EWM25547.1 - 0.34 10.9 4.3 0.32 11.0 0.9 2.2 2 1 0 2 2 2 0 C1-like domain zf-HC5HC2H PF13771.1 EWM25547.1 - 0.39 10.8 3.2 0.25 11.5 0.3 2.0 1 1 1 2 2 2 0 PHD-like zinc-binding domain C1_1 PF00130.17 EWM25547.1 - 0.5 10.1 4.0 1.1 9.0 1.7 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FHA PF00498.21 EWM25548.1 - 2.3e-18 66.0 0.3 4.4e-18 65.1 0.2 1.5 1 0 0 1 1 1 1 FHA domain zf-C3HC4 PF00097.20 EWM25548.1 - 1.8e-06 27.5 0.9 1.8e-06 27.5 0.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EWM25548.1 - 6.4e-05 22.8 1.6 6.4e-05 22.8 1.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EWM25548.1 - 0.00097 18.9 1.9 0.0027 17.5 1.3 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EWM25548.1 - 0.0015 18.1 2.4 0.0015 18.1 1.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EWM25548.1 - 0.0036 17.0 2.8 0.0036 17.0 1.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 EWM25548.1 - 0.0058 16.3 0.6 0.016 14.9 0.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 EWM25548.1 - 0.0059 16.3 1.1 0.019 14.6 0.8 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.1 EWM25548.1 - 0.32 10.8 4.4 0.063 13.0 0.4 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein AAA_13 PF13166.1 EWM25548.1 - 1.3 7.3 12.0 1.8 6.8 8.3 1.1 1 0 0 1 1 1 0 AAA domain Vps51 PF08700.6 EWM25549.1 - 0.00012 21.8 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.4 EWM25549.1 - 0.11 12.4 0.3 0.35 10.8 0.0 1.8 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF1995 PF09353.5 EWM25550.1 - 4.7e-06 26.3 0.0 7.9e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) TatD_DNase PF01026.16 EWM25551.1 - 1.9e-38 132.1 0.0 2.5e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.9 EWM25551.1 - 0.045 13.2 0.0 0.2 11.1 0.0 2.0 2 1 0 2 2 2 0 Amidohydrolase HypD PF01924.11 EWM25551.1 - 0.1 11.3 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Hydrogenase formation hypA family ABC2_membrane PF01061.19 EWM25553.1 - 8.7e-41 139.3 3.8 1.5e-40 138.5 2.6 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EWM25553.1 - 1.5e-21 77.1 0.1 3.9e-21 75.7 0.0 1.7 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.1 EWM25553.1 - 2.5e-06 27.6 0.0 0.00024 21.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 EWM25553.1 - 7.4e-06 25.2 4.1 1.3e-05 24.4 2.8 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_16 PF13191.1 EWM25553.1 - 0.00044 20.2 0.1 0.0011 19.0 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain ABC2_membrane_2 PF12679.2 EWM25553.1 - 0.001 17.9 1.1 0.0019 17.1 0.8 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF258 PF03193.11 EWM25553.1 - 0.0015 17.7 0.0 0.0027 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EWM25553.1 - 0.0016 18.5 0.2 0.0066 16.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain T2SE PF00437.15 EWM25553.1 - 0.0036 16.2 0.0 0.0071 15.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_33 PF13671.1 EWM25553.1 - 0.0059 16.4 0.5 0.024 14.5 0.2 2.1 1 1 1 2 2 2 1 AAA domain SMC_N PF02463.14 EWM25553.1 - 0.011 14.9 0.0 0.036 13.3 0.0 1.7 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EWM25553.1 - 0.011 15.1 0.0 0.061 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EWM25553.1 - 0.011 16.5 0.0 0.029 15.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EWM25553.1 - 0.011 15.1 0.1 0.038 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain AAA_29 PF13555.1 EWM25553.1 - 0.015 14.7 0.3 0.037 13.5 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.7 EWM25553.1 - 0.02 14.5 0.0 0.062 12.9 0.0 1.9 1 0 0 1 1 1 0 NACHT domain Rad17 PF03215.10 EWM25553.1 - 0.021 13.4 0.0 0.032 12.9 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein FtsK_SpoIIIE PF01580.13 EWM25553.1 - 0.035 13.5 0.0 0.082 12.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family cobW PF02492.14 EWM25553.1 - 0.037 13.4 0.1 0.072 12.5 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 EWM25553.1 - 0.048 13.6 0.5 0.15 12.0 0.1 1.9 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.11 EWM25553.1 - 0.055 12.2 0.0 0.091 11.5 0.0 1.2 1 0 0 1 1 1 0 AFG1-like ATPase AAA_19 PF13245.1 EWM25553.1 - 0.065 13.0 0.1 0.21 11.3 0.1 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 EWM25553.1 - 0.069 13.4 0.1 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EWM25553.1 - 0.077 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Arch_ATPase PF01637.13 EWM25553.1 - 0.081 12.6 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_24 PF13479.1 EWM25553.1 - 0.1 12.1 0.1 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EWM25553.1 - 0.11 12.7 0.3 0.18 12.1 0.0 1.4 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.1 EWM25553.1 - 0.15 11.6 0.6 0.62 9.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EWM25553.1 - 0.2 11.5 0.0 0.45 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EWM25553.1 - 0.25 10.8 0.1 0.49 9.8 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation E1_dh PF00676.15 EWM25554.1 - 6.2e-56 189.3 0.1 9.7e-56 188.6 0.1 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_C PF02780.15 EWM25554.1 - 1.3e-22 80.0 0.1 5.9e-22 77.9 0.1 2.1 2 0 0 2 2 2 1 Transketolase, C-terminal domain Transket_pyr PF02779.19 EWM25554.1 - 7e-16 58.2 0.0 1.5e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain TPP_enzyme_C PF02775.16 EWM25554.1 - 9e-05 22.0 2.3 0.00028 20.4 0.0 2.9 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EWM25554.1 - 0.052 12.4 0.0 0.13 11.1 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase SelR PF01641.13 EWM25556.1 - 1.4e-27 95.8 0.0 2e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 SelR domain AF-4 PF05110.8 EWM25556.1 - 0.021 12.7 7.7 0.023 12.6 5.3 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SR-25 PF10500.4 EWM25556.1 - 1.8 7.9 20.4 3 7.2 14.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pheromone PF08015.6 EWM25556.1 - 7.7 7.4 11.2 1.9 9.3 4.6 2.2 2 0 0 2 2 2 0 Fungal mating-type pheromone IF4E PF01652.13 EWM25557.1 - 4.1e-29 101.2 0.2 9.7e-29 100.0 0.2 1.5 1 1 0 1 1 1 1 Eukaryotic initiation factor 4E PQ-loop PF04193.9 EWM25558.1 - 3.9e-21 74.3 1.5 2e-11 43.2 0.4 2.8 2 0 0 2 2 2 2 PQ loop repeat T2SM_b PF10741.4 EWM25558.1 - 0.04 13.5 0.7 1.2 8.8 0.0 2.6 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein M subtype b TruD PF01142.13 EWM25559.1 - 4.2e-06 25.6 0.0 0.01 14.5 0.0 2.1 2 0 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Guanylate_cyc_2 PF09778.4 EWM25562.1 - 9.5e-28 96.8 0.0 6.4e-20 71.2 0.0 3.1 3 0 0 3 3 3 3 Guanylylate cyclase Peptidase_C39 PF03412.10 EWM25562.1 - 0.0034 17.1 0.0 0.006 16.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase C39 family Peptidase_C39_2 PF13529.1 EWM25562.1 - 0.011 16.1 0.1 3.9 7.8 0.0 3.2 3 1 0 3 3 3 0 Peptidase_C39 like family Metallophos PF00149.23 EWM25563.1 - 2.6e-05 23.7 0.6 4.9e-05 22.8 0.4 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EWM25563.1 - 0.00071 19.4 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EWM25564.1 - 1.8e-05 24.2 0.7 2.8e-05 23.6 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EWM25564.1 - 0.00045 20.0 0.1 0.00075 19.3 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RCC1 PF00415.13 EWM25565.1 - 3.5e-12 46.3 1.4 3.1e-05 24.1 0.0 4.5 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EWM25565.1 - 2.7e-07 29.9 5.6 0.00045 19.7 0.3 4.1 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat CDK2AP PF09806.4 EWM25565.1 - 0.018 15.2 4.2 0.03 14.5 2.9 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF4614 PF15391.1 EWM25565.1 - 0.032 14.0 10.8 0.051 13.3 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Hyd_WA PF06462.7 EWM25565.1 - 0.061 12.9 2.0 2.3 7.9 0.2 2.8 3 0 0 3 3 3 0 Propeller SoxE PF06525.6 EWM25565.1 - 0.16 11.2 8.0 0.35 10.1 5.6 1.6 1 0 0 1 1 1 0 Sulfocyanin (SoxE) Pex14_N PF04695.8 EWM25565.1 - 0.24 11.4 9.2 0.16 12.0 4.4 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Period_C PF12114.3 EWM25565.1 - 0.49 9.9 17.6 0.81 9.2 12.2 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region BUD22 PF09073.5 EWM25565.1 - 2 7.4 5.8 2.7 6.9 4.1 1.1 1 0 0 1 1 1 0 BUD22 Macoilin PF09726.4 EWM25565.1 - 4.4 5.4 12.2 5.8 5.0 8.5 1.1 1 0 0 1 1 1 0 Transmembrane protein RCC1 PF00415.13 EWM25566.1 - 2.3e-12 46.9 1.1 2.5e-05 24.3 0.0 4.2 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EWM25566.1 - 1.5e-07 30.7 5.6 0.00038 19.9 0.3 4.2 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat DUF4614 PF15391.1 EWM25566.1 - 0.027 14.2 10.9 0.042 13.6 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) CDK2AP PF09806.4 EWM25566.1 - 0.087 13.0 6.6 0.15 12.3 4.6 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein SoxE PF06525.6 EWM25566.1 - 0.099 11.9 7.6 0.22 10.7 5.3 1.6 1 0 0 1 1 1 0 Sulfocyanin (SoxE) Pex14_N PF04695.8 EWM25566.1 - 0.12 12.3 8.8 0.091 12.8 4.1 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Period_C PF12114.3 EWM25566.1 - 1.2 8.6 19.2 2.1 7.9 13.3 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region RmlD_sub_bind PF04321.12 EWM25568.1 - 4.1e-09 35.7 0.0 6.9e-08 31.7 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EWM25568.1 - 3.5e-08 33.6 0.0 4.7e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EWM25568.1 - 5.8e-06 25.8 0.0 2e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EWM25568.1 - 5.9e-05 22.4 0.0 8.3e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family DnaJ PF00226.26 EWM25569.1 - 2.4e-20 72.0 0.8 2.4e-20 72.0 0.6 1.6 2 0 0 2 2 2 1 DnaJ domain Macoilin PF09726.4 EWM25570.1 - 0.29 9.3 3.7 0.29 9.3 2.6 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF755 PF05501.6 EWM25570.1 - 0.52 10.3 9.8 0.78 9.8 6.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Sulfotransfer_1 PF00685.22 EWM25571.1 - 4.8e-05 22.7 0.4 0.00043 19.6 0.1 2.1 2 0 0 2 2 2 1 Sulfotransferase domain Lin-8 PF03353.10 EWM25571.1 - 1.8 7.7 10.1 3.1 7.0 7.0 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist eIF3_subunit PF08597.5 EWM25571.1 - 6.2 6.3 24.7 12 5.3 17.1 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit TFIIF_alpha PF05793.7 EWM25571.1 - 7.3 4.8 29.1 10 4.3 20.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF498 PF04430.9 EWM25573.1 - 0.14 11.6 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) TRAP-gamma PF07074.7 EWM25574.1 - 6.5 6.2 7.5 12 5.4 5.2 1.3 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Glyco_transf_22 PF03901.12 EWM25575.1 - 1.2e-41 143.0 3.8 1.6e-41 142.6 2.7 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Na_Ca_ex PF01699.19 EWM25576.1 - 4.6e-31 107.2 26.7 6.2e-20 71.2 8.4 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Sulfotransfer_1 PF00685.22 EWM25577.1 - 2.3e-06 27.0 0.1 5.8e-06 25.7 0.1 1.9 1 1 0 1 1 1 1 Sulfotransferase domain Gly_transf_sug PF04488.10 EWM25577.1 - 0.12 12.7 0.0 0.35 11.2 0.0 1.8 1 0 0 1 1 1 0 Glycosyltransferase sugar-binding region containing DXD motif Mating_C PF12737.2 EWM25582.1 - 0.0083 15.0 4.3 0.0092 14.9 3.0 1.0 1 0 0 1 1 1 1 C-terminal domain of homeodomain 1 DUF3727 PF12527.3 EWM25583.1 - 0.00016 21.7 0.8 0.00021 21.3 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3727) DUF3727 PF12527.3 EWM25584.1 - 0.0087 16.1 0.6 0.87 9.7 0.1 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF3727) DUF3521 PF12035.3 EWM25585.1 - 7 6.5 6.7 25 4.8 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3521) Dpoe2NT PF12213.3 EWM25591.1 - 4.2e-10 39.3 0.1 6.2e-10 38.8 0.1 1.2 1 0 0 1 1 1 1 DNA polymerases epsilon N terminal CTNNBL PF08216.6 EWM25591.1 - 0.0065 16.0 0.1 0.5 9.9 0.0 2.1 1 1 1 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear HEAT_2 PF13646.1 EWM25591.1 - 0.053 13.8 1.5 0.1 12.8 1.1 1.5 1 1 0 1 1 1 0 HEAT repeats DUF3944 PF13099.1 EWM25591.1 - 0.06 12.8 0.3 1.7 8.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3944) DUF1188 PF06690.6 EWM25591.1 - 0.064 12.3 0.0 0.089 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) FDX-ACB PF03147.9 EWM25591.1 - 0.072 13.2 0.1 0.22 11.7 0.1 1.7 1 1 1 2 2 2 0 Ferredoxin-fold anticodon binding domain CbbQ_C PF08406.5 EWM25591.1 - 0.074 13.0 1.0 0.25 11.3 0.2 2.0 2 0 0 2 2 2 0 CbbQ/NirQ/NorQ C-terminal TetR_C_6 PF13977.1 EWM25591.1 - 0.12 12.4 1.7 0.13 12.2 0.9 1.3 1 1 0 1 1 1 0 Bacterial transcriptional repressor GTP_EFTU PF00009.22 EWM25593.1 - 0.035 13.5 0.0 0.036 13.4 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain CPSF_A PF03178.10 EWM25595.1 - 2.4e-17 63.0 0.0 3e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 CPSF A subunit region UbiA PF01040.13 EWM25596.1 - 2.3e-20 72.9 27.9 1.4e-12 47.4 2.0 2.7 2 1 0 2 2 2 2 UbiA prenyltransferase family Hira PF07569.6 EWM25598.1 - 0.12 11.5 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 TUP1-like enhancer of split Tom22 PF04281.8 EWM25598.1 - 0.16 11.5 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 PHD PF00628.24 EWM25601.1 - 5.4e-05 22.8 1.0 5.4e-05 22.8 0.7 3.4 3 1 0 3 3 3 1 PHD-finger CDC27 PF09507.5 EWM25601.1 - 0.06 12.5 1.1 0.53 9.4 0.0 2.0 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Ank_2 PF12796.2 EWM25603.1 - 3.1e-13 49.8 0.0 3.9e-08 33.5 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EWM25603.1 - 9.7e-13 48.2 0.0 0.00016 22.0 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EWM25603.1 - 8.6e-10 37.9 0.0 0.0065 16.2 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.1 EWM25603.1 - 1.5e-09 37.1 0.0 1.1 9.6 0.0 5.3 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 EWM25603.1 - 1.8e-08 34.3 0.0 0.0011 19.1 0.0 4.6 3 2 2 5 5 5 1 Ankyrin repeats (many copies) DUF3049 PF11250.3 EWM25603.1 - 0.75 9.6 5.4 2.1 8.2 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3049) Fer4_5 PF12801.2 EWM25604.1 - 4.7e-13 48.7 18.3 4e-09 36.1 2.2 3.0 3 0 0 3 3 3 2 4Fe-4S binding domain CTP_transf_1 PF01148.15 EWM25604.1 - 0.034 13.8 2.3 0.041 13.5 1.6 1.2 1 0 0 1 1 1 0 Cytidylyltransferase family PT PF04886.7 EWM25605.1 - 2.1e-13 49.3 161.2 0.0006 19.0 16.3 7.3 2 1 2 4 4 4 1 PT repeat Vint PF14623.1 EWM25605.1 - 2.3e-09 36.9 0.0 3.6e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Hint-domain Hint PF01079.15 EWM25605.1 - 0.13 11.4 0.0 0.37 9.9 0.0 1.6 2 0 0 2 2 2 0 Hint module Rubis-subs-bind PF09273.6 EWM25606.1 - 2.9e-07 30.4 0.0 6.5e-07 29.3 0.0 1.6 1 1 1 2 2 2 1 Rubisco LSMT substrate-binding SET PF00856.23 EWM25607.1 - 4.5e-08 33.5 0.0 1.2e-07 32.1 0.0 1.7 1 1 0 1 1 1 1 SET domain ENOD93 PF03386.9 EWM25607.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Early nodulin 93 ENOD93 protein TauE PF01925.14 EWM25608.1 - 1.9e-10 40.6 0.9 2e-10 40.5 0.6 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE UPF0016 PF01169.14 EWM25608.1 - 0.04 14.0 0.4 0.058 13.5 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein family UPF0016 TauE PF01925.14 EWM25610.1 - 0.0002 20.8 14.6 0.0033 16.9 10.2 2.0 1 1 0 1 1 1 1 Sulfite exporter TauE/SafE GRIP PF01465.15 EWM25610.1 - 0.065 12.7 0.0 0.32 10.5 0.0 2.0 2 0 0 2 2 2 0 GRIP domain DUF1517 PF07466.6 EWM25610.1 - 0.071 12.0 1.0 0.091 11.7 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) MoeZ_MoeB PF05237.8 EWM25610.1 - 0.2 11.2 0.7 0.36 10.4 0.5 1.6 1 0 0 1 1 1 0 MoeZ/MoeB domain AAA PF00004.24 EWM25611.1 - 8.2e-10 39.0 0.0 1.6e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EWM25611.1 - 1.8e-09 37.8 0.1 5.6e-09 36.2 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EWM25611.1 - 4.2e-08 33.4 0.0 2.8e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EWM25611.1 - 0.00061 19.4 0.2 0.0017 18.0 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain AAA_11 PF13086.1 EWM25611.1 - 0.017 14.6 0.0 0.033 13.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EWM25611.1 - 0.025 14.1 0.1 0.076 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EWM25611.1 - 0.041 13.5 0.0 0.21 11.2 0.0 1.9 1 1 0 1 1 1 0 NACHT domain AAA_5 PF07728.9 EWM25611.1 - 0.093 12.4 0.1 1.4 8.5 0.0 2.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 EWM25611.1 - 0.096 12.3 0.1 0.28 10.8 0.0 1.8 3 0 0 3 3 3 0 NTPase DUF2075 PF09848.4 EWM25611.1 - 0.1 11.5 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.14 EWM25611.1 - 0.12 11.7 0.0 0.33 10.3 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF566 PF04484.7 EWM25614.1 - 9.4 5.6 7.1 10 5.5 4.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) MFS_1 PF07690.11 EWM25616.1 - 2e-22 79.3 20.2 2e-22 79.3 14.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EWM25616.1 - 1.8e-17 63.0 10.0 1.8e-17 63.0 6.9 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter PAP2 PF01569.16 EWM25618.1 - 7e-05 22.5 0.0 0.00034 20.3 0.0 2.0 1 1 0 1 1 1 1 PAP2 superfamily ZYG-11_interact PF05884.7 EWM25619.1 - 0.11 11.5 3.4 0.11 11.5 1.1 1.9 1 1 0 1 1 1 0 Interactor of ZYG-11 MFS_1 PF07690.11 EWM25620.1 - 3.5e-22 78.6 11.1 1e-16 60.6 1.5 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EWM25620.1 - 9.2e-20 70.6 6.4 7.2e-19 67.6 0.6 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Nop14 PF04147.7 EWM25620.1 - 0.0015 16.6 18.3 0.0023 15.9 12.7 1.2 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 EWM25620.1 - 0.028 12.4 8.9 0.064 11.2 5.0 1.9 2 0 0 2 2 2 0 CDC45-like protein DUF4536 PF15055.1 EWM25620.1 - 0.13 12.3 5.7 0.23 11.5 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4536) CENP-B_dimeris PF09026.5 EWM25620.1 - 0.32 11.2 15.6 0.87 9.8 10.8 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4574 PF15141.1 EWM25620.1 - 0.92 9.2 4.7 8.3 6.2 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4574) RRN3 PF05327.6 EWM25620.1 - 1.9 6.4 4.5 2.7 5.9 3.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TRAP_alpha PF03896.11 EWM25620.1 - 4.5 6.1 10.8 8.1 5.3 7.5 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PPP4R2 PF09184.6 EWM25620.1 - 5.9 6.3 14.7 8.9 5.7 10.2 1.3 1 0 0 1 1 1 0 PPP4R2 Lactamase_B_2 PF12706.2 EWM25621.1 - 1.1e-14 54.4 0.1 1.5e-14 53.9 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EWM25621.1 - 2.1e-06 27.5 0.5 3.8e-06 26.6 0.4 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF1854 PF08909.6 EWM25621.1 - 0.11 12.1 0.0 0.28 10.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1854) DAGAT PF03982.8 EWM25622.1 - 1.8e-47 161.4 0.0 3.1e-47 160.6 0.0 1.4 1 1 0 1 1 1 1 Diacylglycerol acyltransferase Patatin PF01734.17 EWM25623.1 - 2.7e-24 86.2 1.7 3.5e-24 85.8 0.1 2.0 2 1 0 2 2 2 1 Patatin-like phospholipase Glyco_tranf_2_4 PF13704.1 EWM25626.1 - 1.6e-08 34.7 0.0 1.1e-06 28.8 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 Epimerase PF01370.16 EWM25627.1 - 7.7e-16 58.2 0.0 1.2e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EWM25627.1 - 4.5e-12 46.3 0.0 7.3e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EWM25627.1 - 3e-08 32.9 0.0 1.6e-07 30.4 0.0 1.8 1 1 1 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 EWM25627.1 - 3e-07 29.4 0.0 4.5e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EWM25627.1 - 4.3e-07 30.0 2.9 0.00014 21.8 1.6 3.5 3 1 0 3 3 3 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EWM25627.1 - 9.3e-05 21.4 0.6 0.16 10.8 0.0 3.1 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein DFP PF04127.10 EWM25627.1 - 0.002 17.7 0.1 0.0032 17.0 0.1 1.4 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein RmlD_sub_bind PF04321.12 EWM25627.1 - 0.0076 15.1 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 EWM25627.1 - 0.016 14.4 0.0 0.04 13.1 0.0 1.6 1 1 0 1 1 1 0 NmrA-like family CoA_binding_2 PF13380.1 EWM25627.1 - 0.074 13.2 0.0 0.22 11.6 0.0 1.8 1 1 0 1 1 1 0 CoA binding domain NAD_binding_2 PF03446.10 EWM25627.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase KR PF08659.5 EWM25627.1 - 0.49 10.0 3.7 1.3 8.6 0.8 2.6 2 1 0 2 2 2 0 KR domain Chorein_N PF12624.2 EWM25628.1 - 1.1e-19 70.0 0.0 2.4e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF1162 PF06650.7 EWM25628.1 - 6.8e-09 35.3 0.0 3.6e-08 32.9 0.0 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1162) ATG_C PF09333.6 EWM25628.1 - 9.4e-09 35.3 0.3 3.4e-08 33.5 0.1 2.0 2 0 0 2 2 2 1 ATG C terminal domain FYVE PF01363.16 EWM25628.1 - 0.00012 21.8 9.5 0.00026 20.8 6.6 1.5 1 0 0 1 1 1 1 FYVE zinc finger Apt1 PF10351.4 EWM25628.1 - 0.0082 15.0 0.0 0.17 10.7 0.0 2.4 2 0 0 2 2 2 1 Golgi-body localisation protein domain FYVE_2 PF02318.11 EWM25628.1 - 0.026 14.3 4.5 0.072 12.9 3.1 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger IBR PF01485.16 EWM25628.1 - 0.061 13.1 2.9 0.13 12.1 2.0 1.5 1 0 0 1 1 1 0 IBR domain Pol_alpha_B_N PF08418.5 EWM25628.1 - 0.5 9.8 2.9 86 2.5 2.0 3.3 3 0 0 3 3 3 0 DNA polymerase alpha subunit B N-terminal DZR PF12773.2 EWM25628.1 - 3 7.7 7.0 7.4 6.4 4.8 1.6 1 0 0 1 1 1 0 Double zinc ribbon adh_short PF00106.20 EWM25630.1 - 2.4e-39 134.9 10.1 4.6e-39 134.0 3.6 2.2 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EWM25630.1 - 1.1e-20 74.0 6.0 2e-20 73.2 1.7 2.2 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EWM25630.1 - 8.4e-20 71.5 2.4 8.4e-20 71.5 1.7 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EWM25630.1 - 0.00035 20.0 0.1 0.00052 19.5 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HAD PF12710.2 EWM25630.1 - 0.018 15.2 0.1 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Eno-Rase_NADH_b PF12242.3 EWM25630.1 - 0.025 14.3 0.8 0.068 12.9 0.6 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DHQ_synthase PF01761.15 EWM25631.1 - 4.6e-60 202.7 0.0 7.9e-60 201.9 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase Aldo_ket_red PF00248.16 EWM25631.1 - 1.1e-31 109.6 0.0 2.1e-31 108.7 0.0 1.4 1 0 0 1 1 1 1 Aldo/keto reductase family Fe-ADH_2 PF13685.1 EWM25631.1 - 2.6e-05 23.6 0.6 9.9e-05 21.7 0.4 2.0 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.14 EWM25631.1 - 0.0049 15.5 2.9 0.099 11.2 2.0 2.9 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase DUF1344 PF07076.6 EWM25631.1 - 0.12 11.9 0.1 0.26 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) FAT PF02259.18 EWM25633.1 - 1.4e-32 113.0 0.0 2.5e-32 112.2 0.0 1.4 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 EWM25633.1 - 5.5e-09 35.8 0.0 1.5e-08 34.4 0.0 1.7 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Nucleoside_tran PF01733.13 EWM25634.1 - 1e-54 185.8 12.3 1.2e-40 139.6 0.2 3.1 3 0 0 3 3 3 3 Nucleoside transporter Nucleoside_tran PF01733.13 EWM25635.1 - 1.2e-54 185.6 12.3 1.3e-40 139.4 0.2 3.2 3 0 0 3 3 3 3 Nucleoside transporter Nucleoside_tran PF01733.13 EWM25636.1 - 1e-54 185.8 12.3 1.2e-40 139.6 0.2 3.1 3 0 0 3 3 3 3 Nucleoside transporter PI3_PI4_kinase PF00454.22 EWM25639.1 - 1.6e-44 152.1 0.0 2.7e-44 151.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EWM25639.1 - 1.5e-13 49.9 0.0 3.3e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.3 EWM25639.1 - 0.1 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) Sec23_trunk PF04811.10 EWM25640.1 - 2.4e-64 217.0 0.0 3.5e-64 216.4 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 EWM25640.1 - 8.2e-18 64.7 0.0 1.4e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EWM25640.1 - 9.1e-17 60.3 2.5 1.7e-16 59.4 1.7 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.10 EWM25640.1 - 4.6e-15 54.9 0.2 8.1e-15 54.1 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.17 EWM25640.1 - 1.4e-05 24.6 0.0 3.1e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat VWA PF00092.23 EWM25640.1 - 0.03 14.0 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain Evr1_Alr PF04777.8 EWM25641.1 - 8.3e-25 86.5 0.0 1.3e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Erv1 / Alr family NeA_P2 PF12312.3 EWM25641.1 - 0.0077 15.4 3.3 0.013 14.7 0.8 2.0 1 1 1 2 2 2 1 Nepovirus subgroup A polyprotein NusG PF02357.14 EWM25642.1 - 2.9e-09 37.0 1.5 7.9e-09 35.6 0.0 2.4 3 0 0 3 3 3 1 Transcription termination factor nusG MCM2_N PF12619.3 EWM25642.1 - 3.1 7.7 10.1 0.87 9.5 1.6 2.2 2 0 0 2 2 2 0 Mini-chromosome maintenance protein 2 ThuA PF06283.6 EWM25643.1 - 5.2e-22 78.6 0.0 9.8e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 Trehalose utilisation Epimerase PF01370.16 EWM25643.1 - 6.1e-15 55.3 0.0 1.2e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ABM PF03992.11 EWM25643.1 - 2.2e-11 43.6 1.7 4.2e-11 42.7 1.2 1.5 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase NAD_binding_10 PF13460.1 EWM25643.1 - 4.8e-11 42.9 0.0 1e-10 41.9 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EWM25643.1 - 3.7e-08 32.5 0.0 1.6e-07 30.5 0.0 1.8 1 1 1 2 2 2 1 Male sterility protein FMN_red PF03358.10 EWM25643.1 - 1.4e-06 27.8 0.0 3.7e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 NADPH-dependent FMN reductase 3Beta_HSD PF01073.14 EWM25643.1 - 1.5e-06 27.1 0.0 2.3e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EWM25643.1 - 5e-05 23.2 4.5 0.0008 19.3 1.5 3.3 3 1 0 3 3 3 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EWM25643.1 - 0.0012 17.8 0.5 0.68 8.7 0.0 3.0 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein DFP PF04127.10 EWM25643.1 - 0.008 15.8 0.1 0.015 14.8 0.1 1.5 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein RmlD_sub_bind PF04321.12 EWM25643.1 - 0.033 13.0 0.0 0.059 12.2 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Flavodoxin_2 PF02525.12 EWM25643.1 - 0.038 13.4 0.0 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 Flavodoxin-like fold NmrA PF05368.8 EWM25643.1 - 0.11 11.6 0.0 0.23 10.6 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family PT PF04886.7 EWM25644.1 - 0.08 12.2 104.8 9.6e+03 -4.0 24.2 5.6 1 1 1 2 2 2 0 PT repeat RRM_1 PF00076.17 EWM25645.1 - 3.9e-18 64.8 0.0 5.8e-18 64.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM25645.1 - 9.4e-14 51.1 0.0 1.6e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM25645.1 - 1.3e-09 37.7 0.1 2.4e-09 36.9 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sugar_tr PF00083.19 EWM25646.1 - 2.2e-82 277.0 25.0 2.8e-82 276.7 17.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Aldo_ket_red PF00248.16 EWM25646.1 - 5.4e-38 130.4 0.0 7.5e-38 129.9 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.11 EWM25646.1 - 1.5e-22 79.8 48.4 2.9e-18 65.7 15.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pro_isomerase PF00160.16 EWM25647.1 - 7.9e-48 162.5 0.1 1.1e-47 162.1 0.1 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SAP PF02037.22 EWM25649.1 - 2.8e-11 42.6 0.1 5.3e-11 41.7 0.1 1.5 1 0 0 1 1 1 1 SAP domain M-inducer_phosp PF06617.8 EWM25649.1 - 0.15 11.1 0.1 0.29 10.1 0.1 1.4 1 0 0 1 1 1 0 M-phase inducer phosphatase CAF1 PF04857.15 EWM25650.1 - 1.7e-65 220.9 0.0 2.4e-65 220.4 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease EPTP PF03736.12 EWM25651.1 - 1.2e-05 24.9 0.2 1.9 8.3 0.0 4.4 5 0 0 5 5 5 3 EPTP domain YqjK PF13997.1 EWM25651.1 - 0.08 13.1 1.7 14 5.9 0.2 3.7 2 1 2 4 4 4 0 YqjK-like protein WW PF00397.21 EWM25652.1 - 6e-14 51.5 2.9 5.3e-10 38.9 1.5 2.7 2 0 0 2 2 2 2 WW domain MbtH PF03621.8 EWM25652.1 - 0.022 14.1 4.5 0.38 10.1 0.0 3.1 3 0 0 3 3 3 0 MbtH-like protein WW PF00397.21 EWM25653.1 - 3.7e-14 52.2 2.9 4.1e-10 39.3 1.5 2.7 2 0 0 2 2 2 2 WW domain MbtH PF03621.8 EWM25653.1 - 0.014 14.7 4.5 0.3 10.4 0.0 3.1 3 0 0 3 3 3 0 MbtH-like protein LisH PF08513.6 EWM25654.1 - 6.6e-11 41.5 0.1 1.3e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 LisH PAH PF02671.16 EWM25655.1 - 1.4e-18 66.1 1.0 2.1e-18 65.6 0.7 1.3 1 0 0 1 1 1 1 Paired amphipathic helix repeat CHASE3 PF05227.8 EWM25655.1 - 0.0027 17.3 1.3 0.0039 16.8 0.9 1.2 1 0 0 1 1 1 1 CHASE3 domain DUF2247 PF10004.4 EWM25655.1 - 0.0043 16.7 0.5 0.0052 16.5 0.3 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2247) RINGv PF12906.2 EWM25660.1 - 3e-14 52.7 9.4 4.9e-14 52.1 6.5 1.4 1 0 0 1 1 1 1 RING-variant domain zf-Apc11 PF12861.2 EWM25660.1 - 0.00066 19.4 2.2 0.0013 18.5 1.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EWM25660.1 - 0.061 13.4 2.8 0.13 12.4 1.9 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger IncA PF04156.9 EWM25660.1 - 0.076 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 IncA protein zf-RING_2 PF13639.1 EWM25660.1 - 0.13 12.0 8.1 0.31 10.9 5.6 1.7 1 0 0 1 1 1 0 Ring finger domain FANCL_C PF11793.3 EWM25660.1 - 0.37 10.7 3.5 0.71 9.8 2.4 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.1 EWM25660.1 - 3.1 7.5 7.1 9.2 6.0 4.9 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Lipoxygenase PF00305.14 EWM25661.1 - 6.5e-20 70.7 0.0 1e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Lipoxygenase Methyltransf_16 PF10294.4 EWM25663.1 - 2.3e-05 23.9 0.0 3.3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Hamartin PF04388.7 EWM25663.1 - 0.18 10.4 0.8 0.2 10.2 0.5 1.0 1 0 0 1 1 1 0 Hamartin protein CAP_N PF01213.14 EWM25663.1 - 9.5 5.4 7.5 13 4.9 5.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal zf-RNPHF PF08080.7 EWM25665.1 - 0.057 12.9 0.4 0.25 10.8 0.0 2.0 2 0 0 2 2 2 0 RNPHF zinc finger Metal_resist PF13801.1 EWM25666.1 - 0.7 9.8 5.6 0.37 10.7 2.5 1.7 1 1 1 2 2 2 0 Heavy-metal resistance Myb_DNA-binding PF00249.26 EWM25668.1 - 8.3e-12 44.9 0.8 3.2e-11 43.1 0.4 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EWM25668.1 - 0.00015 21.7 0.2 0.00034 20.6 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain ER_lumen_recept PF00810.13 EWM25670.1 - 9e-34 117.0 7.8 9e-34 117.0 5.4 2.3 2 1 0 2 2 2 1 ER lumen protein retaining receptor DUF605 PF04652.11 EWM25671.1 - 5.7 6.2 9.0 6.7 6.0 6.2 1.1 1 0 0 1 1 1 0 Vta1 like Fer2 PF00111.22 EWM25673.1 - 2.8e-12 46.2 0.2 4.4e-12 45.5 0.2 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain GCS PF03074.11 EWM25674.1 - 9.6e-09 34.7 0.0 1e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 Glutamate-cysteine ligase IBR PF01485.16 EWM25675.1 - 0.018 14.8 4.4 0.057 13.2 0.4 2.2 2 0 0 2 2 2 0 IBR domain eIF-3c_N PF05470.7 EWM25676.1 - 1.4e-60 205.0 6.0 1.7e-60 204.7 4.1 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EWM25676.1 - 5.5e-13 49.1 0.0 1.2e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 PCI domain eIF-3c_N PF05470.7 EWM25677.1 - 1.4e-60 205.0 6.0 1.7e-60 204.7 4.1 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EWM25677.1 - 5.5e-13 49.1 0.0 1.2e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 PCI domain MFS_1 PF07690.11 EWM25678.1 - 5.2e-27 94.4 28.6 5.2e-27 94.4 19.8 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily eIF-3c_N PF05470.7 EWM25680.1 - 4.6e-14 51.4 0.0 5.2e-14 51.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Mei4 PF13971.1 EWM25680.1 - 0.009 15.0 0.1 0.011 14.7 0.1 1.1 1 0 0 1 1 1 1 Meiosis-specific protein Mei4 PspA_IM30 PF04012.7 EWM25680.1 - 0.05 12.9 0.9 0.065 12.5 0.6 1.2 1 0 0 1 1 1 0 PspA/IM30 family Cnd1_N PF12922.2 EWM25680.1 - 0.093 12.3 0.1 0.33 10.5 0.0 1.8 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term Env-gp36 PF09590.5 EWM25680.1 - 0.11 10.6 0.0 0.11 10.6 0.0 1.1 1 0 0 1 1 1 0 Lentivirus surface glycoprotein AF-4 PF05110.8 EWM25680.1 - 0.13 10.0 13.1 0.17 9.7 9.0 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Cwf_Cwc_15 PF04889.7 EWM25680.1 - 0.49 10.0 7.6 0.65 9.6 5.2 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Na_trans_assoc PF06512.8 EWM25680.1 - 7.8 6.3 8.3 11 5.9 5.7 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated TORC_M PF12885.2 EWM25681.1 - 1 9.1 5.1 1.8 8.3 3.5 1.3 1 0 0 1 1 1 0 Transducer of regulated CREB activity middle domain Pkinase PF00069.20 EWM25682.1 - 6.7e-06 25.4 0.0 0.16 11.1 0.0 2.9 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EWM25682.1 - 0.0039 16.2 0.0 1.2 8.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DUF2043 PF09740.4 EWM25683.1 - 5.9 7.0 9.4 1.8 8.7 2.7 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2043) POP1 PF06978.6 EWM25684.1 - 1.8e-15 57.1 0.1 3.2e-15 56.2 0.1 1.4 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 Sm_multidrug_ex PF06695.6 EWM25686.1 - 6.9e-25 87.5 5.9 6.9e-25 87.5 4.1 2.4 2 1 0 2 2 2 1 Putative small multi-drug export protein NADHdeh_related PF10125.4 EWM25686.1 - 0.06 12.5 1.1 3.1 6.8 0.0 2.2 2 0 0 2 2 2 0 NADH dehydrogenase I, subunit N related protein Cyclin PF08613.6 EWM25689.1 - 4.2e-08 33.7 0.1 8.9e-08 32.6 0.0 1.6 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EWM25689.1 - 5.7e-08 32.3 0.0 9.6e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain NAD_binding_10 PF13460.1 EWM25690.1 - 4.9e-25 88.5 0.2 7.1e-25 88.0 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EWM25690.1 - 2.2e-11 43.0 0.0 3e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EWM25690.1 - 1.7e-05 24.1 0.1 8e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.16 EWM25690.1 - 4.4e-05 23.0 0.2 0.00012 21.5 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EWM25690.1 - 0.044 12.6 0.0 0.084 11.7 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain eIF2A PF08662.6 EWM25691.1 - 1.4e-37 129.2 0.1 9.6e-35 120.0 0.0 3.8 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 EWM25691.1 - 8.3e-06 25.3 0.0 1.9e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM25691.1 - 2.3e-05 24.3 0.0 5.1e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Gmad1 PF10647.4 EWM25691.1 - 0.0027 17.1 0.0 0.0044 16.4 0.0 1.3 1 0 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain RRM_5 PF13893.1 EWM25691.1 - 0.016 15.0 0.0 0.057 13.2 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.7 EWM25691.1 - 0.047 13.6 0.1 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif 2 Mito_carr PF00153.22 EWM25692.1 - 1.6e-42 143.0 8.2 3.9e-22 77.7 0.1 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein DnaJ PF00226.26 EWM25696.1 - 3.2e-16 58.8 0.2 3.2e-16 58.8 0.1 2.6 3 0 0 3 3 3 1 DnaJ domain Myb_DNA-binding PF00249.26 EWM25696.1 - 1e-09 38.2 5.9 0.00012 22.0 0.1 3.7 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EWM25696.1 - 3e-07 30.4 1.3 0.049 13.7 0.5 4.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain TerC PF03741.11 EWM25697.1 - 9.7e-52 175.0 5.6 1.9e-51 174.1 3.9 1.5 1 0 0 1 1 1 1 Integral membrane protein TerC family DUF4131 PF13567.1 EWM25697.1 - 1.4 8.2 7.0 8.2 5.7 0.2 3.6 2 1 0 3 3 3 0 Domain of unknown function (DUF4131) AAA_25 PF13481.1 EWM25698.1 - 0.00019 20.9 0.1 0.0065 15.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EWM25698.1 - 0.0003 20.7 0.0 0.00047 20.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EWM25698.1 - 0.00036 20.7 0.0 0.00061 19.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EWM25698.1 - 0.0023 17.6 0.0 0.017 14.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EWM25698.1 - 0.0027 17.8 0.0 0.0098 16.0 0.0 1.9 1 1 0 1 1 1 1 RNA helicase AAA_16 PF13191.1 EWM25698.1 - 0.0049 16.8 0.0 0.35 10.8 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 EWM25698.1 - 0.0056 16.5 0.0 0.015 15.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EWM25698.1 - 0.0074 16.4 0.1 0.18 11.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain Torsin PF06309.6 EWM25698.1 - 0.0097 15.7 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 Torsin Arch_ATPase PF01637.13 EWM25698.1 - 0.012 15.3 0.0 0.08 12.6 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase AAA_19 PF13245.1 EWM25698.1 - 0.038 13.7 0.1 0.09 12.5 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 EWM25698.1 - 0.039 14.7 0.0 0.074 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cation_efflux PF01545.16 EWM25699.1 - 3.5e-38 131.2 6.2 4.6e-38 130.9 4.3 1.1 1 0 0 1 1 1 1 Cation efflux family NADH_B2 PF14813.1 EWM25700.1 - 0.00017 21.2 1.9 0.00028 20.4 1.3 1.3 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 E1-E2_ATPase PF00122.15 EWM25701.1 - 8e-63 211.5 0.1 2.3e-62 210.0 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EWM25701.1 - 2.7e-45 154.1 0.2 7.8e-45 152.6 0.1 1.8 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EWM25701.1 - 4.6e-30 105.6 0.0 1.3e-28 100.8 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EWM25701.1 - 3.6e-20 71.7 0.0 7.3e-20 70.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EWM25701.1 - 6.1e-16 57.6 0.0 1.4e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EWM25701.1 - 2.6e-12 47.3 0.0 6.8e-12 45.9 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EWM25701.1 - 1.2e-05 24.9 1.0 8.6e-05 22.2 0.3 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SPC25 PF06703.6 EWM25703.1 - 3.9e-26 91.5 0.0 4.8e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) CD52 PF15116.1 EWM25703.1 - 0.034 13.9 0.2 2.2 8.1 0.1 2.5 2 0 0 2 2 2 0 CAMPATH-1 antigen Cys_Met_Meta_PP PF01053.15 EWM25704.1 - 3.7e-33 114.3 0.0 5e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EWM25704.1 - 2.3e-05 23.5 0.0 3.6e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II MAPEG PF01124.13 EWM25706.1 - 3.4e-16 59.0 0.2 4.9e-16 58.5 0.2 1.3 1 0 0 1 1 1 1 MAPEG family PDDEXK_1 PF12705.2 EWM25707.1 - 0.00013 21.4 0.2 0.00033 20.1 0.1 1.7 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily UvrD_C PF13361.1 EWM25707.1 - 0.00035 20.1 0.0 0.0012 18.3 0.0 1.9 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 EWM25707.1 - 0.00062 19.1 0.0 0.0011 18.2 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_12 PF13087.1 EWM25707.1 - 0.0043 16.4 0.0 0.0086 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 EWM25707.1 - 0.015 14.5 0.1 0.88 8.7 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein NAP PF00956.13 EWM25708.1 - 4e-58 196.4 0.0 5.5e-58 195.9 0.0 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Pkinase PF00069.20 EWM25711.1 - 6.6e-49 166.3 0.0 1.2e-47 162.2 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM25711.1 - 8.1e-29 100.4 0.0 9e-28 97.0 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EWM25711.1 - 0.00044 19.2 0.1 0.01 14.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Acyltransferase PF01553.16 EWM25712.1 - 3.1e-19 68.7 0.0 4.9e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase CMAS PF02353.15 EWM25713.1 - 9.9e-39 133.0 0.2 1.4e-22 80.0 0.0 2.1 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EWM25713.1 - 6e-12 45.5 0.0 1e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM25713.1 - 2.4e-11 44.1 0.0 5.3e-11 43.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM25713.1 - 5.1e-11 42.9 0.0 8.1e-05 23.0 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 EWM25713.1 - 5.2e-10 39.1 0.0 7.4e-07 28.8 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EWM25713.1 - 2.8e-09 37.3 0.0 9.7e-09 35.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EWM25713.1 - 6.1e-07 28.9 0.0 2.2e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EWM25713.1 - 0.00061 20.1 0.0 0.026 14.8 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EWM25713.1 - 0.0022 17.0 0.0 0.0041 16.2 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase TehB PF03848.9 EWM25713.1 - 0.013 14.6 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_26 PF13659.1 EWM25713.1 - 0.14 12.2 0.0 0.53 10.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 EWM25713.1 - 0.15 10.9 0.0 0.43 9.3 0.0 1.7 2 0 0 2 2 2 0 DREV methyltransferase Pkinase PF00069.20 EWM25714.1 - 8.5e-89 297.1 0.0 3.8e-53 180.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EWM25714.1 - 7.7e-77 257.8 0.0 4.2e-62 209.5 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase ANTH PF07651.11 EWM25714.1 - 1.7e-13 49.8 0.0 4.3e-09 35.4 0.0 3.1 3 0 0 3 3 3 2 ANTH domain Kinase-like PF14531.1 EWM25714.1 - 5.4e-05 22.2 0.0 1.1 8.1 0.0 3.5 3 0 0 3 3 3 2 Kinase-like Glycolytic PF00274.14 EWM25715.1 - 3.7e-161 535.3 0.0 4.3e-161 535.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Aldedh PF00171.17 EWM25716.1 - 4.7e-129 430.7 0.1 5.7e-129 430.4 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EWM25716.1 - 0.035 12.8 0.0 0.057 12.1 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Lipocalin_2 PF08212.7 EWM25717.1 - 1.3e-06 28.2 0.0 0.052 13.3 0.0 2.1 2 0 0 2 2 2 2 Lipocalin-like domain EamA PF00892.15 EWM25718.1 - 3.4e-11 43.2 30.0 5.1e-08 33.0 2.4 3.3 3 0 0 3 3 3 3 EamA-like transporter family DUF914 PF06027.7 EWM25718.1 - 0.0015 17.4 1.7 0.0015 17.4 1.2 2.0 3 0 0 3 3 3 1 Eukaryotic protein of unknown function (DUF914) TPT PF03151.11 EWM25718.1 - 0.031 13.9 0.5 0.031 13.9 0.3 2.7 3 0 0 3 3 3 0 Triose-phosphate Transporter family Rhomboid PF01694.17 EWM25720.1 - 3.1e-28 98.6 9.1 5.6e-28 97.7 6.3 1.4 1 0 0 1 1 1 1 Rhomboid family DER1 PF04511.10 EWM25720.1 - 0.074 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Der1-like family Pkinase PF00069.20 EWM25722.1 - 1.4e-30 106.3 0.0 2.3e-30 105.6 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM25722.1 - 3e-06 26.4 0.0 4.4e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase NUDIX PF00293.23 EWM25723.1 - 3.3e-12 46.2 0.0 5.4e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Nudix_N_2 PF14803.1 EWM25723.1 - 0.0031 17.1 0.1 0.0076 15.9 0.0 1.7 1 0 0 1 1 1 1 Nudix N-terminal DMAP1 PF05499.7 EWM25724.1 - 0.0012 18.4 0.0 0.0036 16.8 0.0 1.8 1 0 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) End3 PF12761.2 EWM25724.1 - 0.035 13.7 0.4 0.059 13.0 0.3 1.3 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Vfa1 PF08432.5 EWM25724.1 - 1.4 8.8 6.9 0.36 10.8 0.5 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 bZIP_1 PF00170.16 EWM25725.1 - 2.3e-10 40.2 9.4 2.3e-10 40.2 6.5 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EWM25725.1 - 3.1e-06 26.9 12.3 3.1e-06 26.9 8.6 2.9 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.16 EWM25726.1 - 3e-10 39.9 9.4 3e-10 39.9 6.5 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EWM25726.1 - 3.9e-06 26.5 12.3 3.9e-06 26.5 8.5 2.8 3 0 0 3 3 3 1 Basic region leucine zipper Aminotran_4 PF01063.14 EWM25727.1 - 1.3e-18 67.2 0.0 3.4e-17 62.6 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class IV Aminotran_4 PF01063.14 EWM25728.1 - 1.3e-18 67.2 0.0 3.4e-17 62.6 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class IV PPTA PF01239.17 EWM25729.1 - 1.6e-14 52.4 10.5 0.00028 20.0 0.0 5.7 6 0 0 6 6 6 4 Protein prenyltransferase alpha subunit repeat DSHCT PF08148.7 EWM25730.1 - 1.2e-58 197.3 2.1 1.5e-58 197.0 0.4 2.0 2 0 0 2 2 2 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.1 EWM25730.1 - 2.9e-55 187.3 0.0 4.3e-55 186.7 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.24 EWM25730.1 - 5.1e-20 71.6 0.1 2.9e-19 69.1 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EWM25730.1 - 6.6e-08 32.3 0.0 1.8e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Neur_chan_memb PF02932.11 EWM25731.1 - 1.5 8.6 4.8 2.3 8.0 3.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4551 PF15087.1 EWM25731.1 - 5.5 5.2 10.5 7.3 4.8 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Arrestin_N PF00339.24 EWM25732.1 - 5.2e-17 62.0 0.0 2e-14 53.6 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EWM25732.1 - 1.1e-10 41.7 0.0 2e-06 27.9 0.0 2.9 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.2 EWM25732.1 - 0.1 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Arrestin_N terminal like FAP PF07174.6 EWM25732.1 - 0.56 9.4 7.9 0.92 8.7 5.5 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DnaJ PF00226.26 EWM25733.1 - 4.6e-06 26.2 0.0 8e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Polysacc_synt_3 PF13440.1 EWM25734.1 - 0.013 14.9 1.1 0.023 14.1 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein zf-C3HC4_3 PF13920.1 EWM25735.1 - 4.9e-07 29.3 13.9 1e-06 28.3 9.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EWM25735.1 - 7.4e-05 22.3 11.9 0.00024 20.6 8.2 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EWM25735.1 - 9.3e-05 22.3 13.8 0.00033 20.6 9.6 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EWM25735.1 - 0.08 12.6 14.2 0.17 11.6 9.8 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EWM25735.1 - 0.19 11.6 12.0 0.86 9.5 8.3 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EWM25735.1 - 2 8.2 15.2 3.4 7.5 9.8 1.9 1 1 1 2 2 2 0 Ring finger domain PMP22_Claudin PF00822.15 EWM25736.1 - 0.017 14.7 2.5 0.032 13.9 1.6 1.7 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family UPF0182 PF03699.8 EWM25736.1 - 0.4 8.5 2.3 0.62 7.9 1.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Amastin PF07344.6 EWM25736.1 - 1.5 8.4 7.4 0.051 13.1 1.0 1.7 2 0 0 2 2 2 0 Amastin surface glycoprotein ABC2_membrane PF01061.19 EWM25738.1 - 6.6e-29 100.5 22.9 6.6e-29 100.5 15.9 2.0 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.22 EWM25738.1 - 8.8e-22 77.8 0.0 1.5e-21 77.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EWM25738.1 - 0.00072 19.5 0.0 0.96 9.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EWM25738.1 - 0.0028 17.1 0.1 0.0074 15.7 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 EWM25738.1 - 0.0075 15.5 0.0 0.96 8.6 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain EGF_2 PF07974.8 EWM25738.1 - 0.013 15.6 1.1 0.013 15.6 0.8 2.0 2 0 0 2 2 1 0 EGF-like domain AAA_25 PF13481.1 EWM25738.1 - 0.017 14.5 0.9 0.17 11.2 0.6 2.5 2 1 0 2 2 2 0 AAA domain DUF258 PF03193.11 EWM25738.1 - 0.028 13.6 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EWM25738.1 - 0.059 13.3 0.1 0.15 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain hEGF PF12661.2 EWM25738.1 - 0.075 13.1 8.3 0.062 13.3 4.1 2.3 2 0 0 2 2 2 0 Human growth factor-like EGF AAA_22 PF13401.1 EWM25738.1 - 0.092 12.8 0.0 0.21 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EWM25738.1 - 0.18 12.6 0.0 0.35 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EWM25738.1 - 0.28 11.4 0.0 0.45 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EWM25738.1 - 0.28 11.4 0.0 0.5 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Laminin_EGF PF00053.19 EWM25738.1 - 1 9.3 7.9 0.15 11.9 2.5 1.8 2 0 0 2 2 1 0 Laminin EGF-like (Domains III and V) His_Phos_2 PF00328.17 EWM25739.1 - 1.8e-17 63.7 0.0 2.3e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) TruD PF01142.13 EWM25740.1 - 4.7e-32 111.1 0.6 6.5e-16 57.9 0.0 5.2 5 0 0 5 5 5 5 tRNA pseudouridine synthase D (TruD) FAD_binding_4 PF01565.18 EWM25741.1 - 7.7e-26 90.2 0.4 1.2e-25 89.5 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.9 EWM25741.1 - 3.9e-19 69.2 0.0 3.1e-12 46.6 0.0 2.9 2 1 0 2 2 2 2 D-arabinono-1,4-lactone oxidase FAD_binding_5 PF00941.16 EWM25741.1 - 0.092 12.1 0.1 0.21 10.9 0.0 1.6 1 1 1 2 2 2 0 FAD binding domain in molybdopterin dehydrogenase Zeta_toxin PF06414.7 EWM25742.1 - 8.1e-15 54.4 2.7 1.5e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 Zeta toxin EIF_2_alpha PF07541.7 EWM25744.1 - 1.4e-33 114.9 0.0 3.1e-33 113.9 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EWM25744.1 - 2e-10 40.6 0.5 4.7e-10 39.4 0.3 1.7 1 0 0 1 1 1 1 S1 RNA binding domain MamL-1 PF09596.5 EWM25744.1 - 0.22 11.3 2.7 13 5.6 0.0 3.3 3 0 0 3 3 3 0 MamL-1 domain Metallophos PF00149.23 EWM25745.1 - 6.5e-18 64.8 1.0 1.1e-17 64.0 0.7 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 EWM25745.1 - 4.6e-12 45.8 0.1 1.1e-11 44.6 0.1 1.6 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 EWM25745.1 - 7e-08 31.4 0.1 3.3e-07 29.2 0.1 1.9 2 0 0 2 2 2 1 PhoD-like phosphatase Metallophos_2 PF12850.2 EWM25745.1 - 5e-05 23.1 0.0 9.6e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PUF PF00806.14 EWM25745.1 - 0.026 13.9 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat DUF3376 PF11856.3 EWM25746.1 - 0.015 14.7 0.9 0.019 14.3 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3376) Med9 PF07544.8 EWM25746.1 - 0.2 11.3 1.4 0.8 9.4 0.0 2.3 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 SET PF00856.23 EWM25747.1 - 6.9e-07 29.7 0.0 1.9e-06 28.2 0.0 1.7 1 1 0 1 1 1 1 SET domain GSCFA PF08885.6 EWM25748.1 - 2.1e-34 119.1 0.0 2.6e-21 76.3 0.0 2.1 2 0 0 2 2 2 2 GSCFA family PGM_PMM_II PF02879.11 EWM25749.1 - 2.7e-18 66.1 0.0 5.7e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_I PF02878.11 EWM25749.1 - 5.5e-15 55.0 0.0 1.2e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EWM25749.1 - 1.2e-11 44.6 0.0 2.2e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Methyltransf_3 PF01596.12 EWM25750.1 - 6.7e-33 113.4 0.0 1.6e-31 109.0 0.0 2.3 1 1 0 1 1 1 1 O-methyltransferase Rhodanese PF00581.15 EWM25750.1 - 1.6e-10 41.3 0.0 3.7e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Methyltransf_24 PF13578.1 EWM25750.1 - 4.1e-10 40.4 0.0 2.2e-09 38.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain PB1 PF00564.19 EWM25750.1 - 0.013 15.1 0.3 0.096 12.3 0.1 2.3 2 0 0 2 2 2 0 PB1 domain COG4 PF08318.7 EWM25751.1 - 2.8e-28 98.6 0.0 4.5e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 COG4 transport protein Taeniidae_ag PF05596.6 EWM25751.1 - 0.043 13.6 0.1 0.75 9.6 0.0 2.7 2 0 0 2 2 2 0 Taeniidae antigen zf-H2C2 PF09337.5 EWM25751.1 - 0.082 12.3 0.2 0.26 10.7 0.0 1.9 2 0 0 2 2 2 0 His(2)-Cys(2) zinc finger Atg14 PF10186.4 EWM25751.1 - 0.11 11.4 0.3 0.19 10.6 0.2 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1664 PF07889.7 EWM25751.1 - 0.13 12.0 0.5 0.4 10.4 0.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF106 PF01956.11 EWM25752.1 - 4.6e-35 120.6 0.0 5.9e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 DUF1757 PF08560.5 EWM25753.1 - 3.4e-10 39.8 0.0 4.6e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1757) ELO PF01151.13 EWM25754.1 - 2e-55 187.8 29.2 3.2e-55 187.1 20.2 1.3 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.13 EWM25755.1 - 3.6e-60 203.3 17.8 4.7e-60 202.9 12.3 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family SNF2_N PF00176.18 EWM25756.1 - 3.5e-59 200.0 0.0 4.9e-59 199.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EWM25756.1 - 2.8e-14 52.7 0.0 5.7e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EWM25756.1 - 0.016 14.0 0.0 0.039 12.7 0.0 1.5 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 Pyrophosphatase PF00719.14 EWM25757.1 - 3.8e-47 159.6 0.0 5.2e-47 159.1 0.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Dus PF01207.12 EWM25758.1 - 2.7e-53 180.8 0.1 2.3e-52 177.7 0.1 2.0 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 EWM25758.1 - 0.036 13.3 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein TMP-TENI PF02581.12 EWM25758.1 - 0.036 13.1 0.0 0.061 12.4 0.0 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI PEP_mutase PF13714.1 EWM25758.1 - 0.066 12.4 0.2 0.12 11.5 0.1 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase Chloroa_b-bind PF00504.16 EWM25759.1 - 9.3e-39 133.1 0.0 8.8e-24 84.5 0.0 2.2 2 0 0 2 2 2 2 Chlorophyll A-B binding protein PT-VENN PF04829.8 EWM25759.1 - 0.016 14.7 0.7 0.016 14.7 0.5 1.8 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif Ribosomal_S15 PF00312.17 EWM25760.1 - 8.9e-24 83.0 0.1 1.2e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 Ribosomal_L32p PF01783.18 EWM25761.1 - 1.4e-07 31.5 6.0 2.1e-07 30.9 4.2 1.3 1 0 0 1 1 1 1 Ribosomal L32p protein family zf-IS66 PF13005.2 EWM25761.1 - 0.036 14.0 5.5 1.2 9.1 0.1 2.7 2 1 0 2 2 2 0 zinc-finger binding domain of transposase IS66 GFA PF04828.9 EWM25761.1 - 0.04 13.8 0.1 0.064 13.2 0.1 1.3 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 EWM25761.1 - 0.072 12.3 0.2 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-HIT PF04438.11 EWM25761.1 - 0.38 10.4 5.4 0.45 10.2 1.8 2.1 1 1 1 2 2 2 0 HIT zinc finger DUF1610 PF07754.6 EWM25761.1 - 0.41 10.8 2.8 1.9 8.6 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) RINGv PF12906.2 EWM25762.1 - 0.064 13.3 4.2 0.063 13.3 1.5 2.1 2 1 0 2 2 2 0 RING-variant domain Glyco_hydro_2_C PF02836.12 EWM25763.1 - 1.8e-97 325.8 0.0 2.3e-97 325.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 EWM25763.1 - 3e-50 170.8 0.0 5.3e-50 169.9 0.0 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.13 EWM25763.1 - 7.6e-40 136.1 0.0 1.9e-39 134.9 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 EWM25763.1 - 4.6e-09 36.7 0.0 1.1e-08 35.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_72 PF03198.9 EWM25763.1 - 0.0056 15.7 0.0 0.0096 14.9 0.0 1.2 1 0 0 1 1 1 1 Glucanosyltransferase Mito_carr PF00153.22 EWM25764.1 - 2.9e-69 228.8 0.6 1.5e-23 82.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 EWM25764.1 - 0.086 12.8 3.4 7.1 6.6 0.1 3.0 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Chloroa_b-bind PF00504.16 EWM25765.1 - 7.3e-33 114.0 0.0 1e-32 113.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Tubulin PF00091.20 EWM25766.1 - 4.6e-33 114.8 1.1 1.6e-32 113.0 0.7 1.9 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.3 EWM25766.1 - 3.8e-31 107.0 1.6 1e-30 105.6 1.1 1.8 1 0 0 1 1 1 1 FtsZ family, C-terminal domain Phosphoprotein PF00922.12 EWM25766.1 - 0.16 11.1 3.1 0.38 9.9 2.1 1.6 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein MOZ_SAS PF01853.13 EWM25768.1 - 1.5e-88 294.9 1.7 2.2e-88 294.4 1.2 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EWM25768.1 - 3.9e-14 52.0 3.4 2e-13 49.7 1.1 2.8 2 1 0 2 2 2 1 RNA binding activity-knot of a chromodomain PEARLI-4 PF05278.7 EWM25768.1 - 0.0081 15.5 0.1 0.015 14.6 0.1 1.5 1 0 0 1 1 1 1 Arabidopsis phospholipase-like protein (PEARLI 4) Adap_comp_sub PF00928.16 EWM25769.1 - 2.6e-86 288.9 0.0 3.5e-86 288.5 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EWM25769.1 - 1.1e-06 28.4 0.9 1.8e-06 27.7 0.6 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 EWM25769.1 - 0.0009 18.4 0.0 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Longin PF13774.1 EWM25769.1 - 0.047 13.2 0.2 0.11 12.0 0.2 1.6 1 0 0 1 1 1 0 Regulated-SNARE-like domain Ph1570 PF09638.5 EWM25769.1 - 0.076 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Ph1570 protein Adap_comp_sub PF00928.16 EWM25770.1 - 5.4e-86 287.9 0.0 7.7e-86 287.4 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EWM25770.1 - 1.2e-06 28.3 0.9 1.9e-06 27.6 0.6 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 EWM25770.1 - 0.00093 18.4 0.0 0.0017 17.6 0.0 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Longin PF13774.1 EWM25770.1 - 0.05 13.1 0.2 0.12 11.9 0.2 1.6 1 0 0 1 1 1 0 Regulated-SNARE-like domain Ph1570 PF09638.5 EWM25770.1 - 0.082 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Ph1570 protein WD40 PF00400.27 EWM25771.1 - 7.4e-19 66.8 0.5 3.8e-07 29.7 0.0 5.2 5 1 0 5 5 5 3 WD domain, G-beta repeat RCC1_2 PF13540.1 EWM25771.1 - 0.23 11.1 5.4 0.17 11.5 0.5 2.6 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat PAXIP1_C PF15364.1 EWM25774.1 - 0.67 9.8 6.3 1.1 9.2 4.4 1.4 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein MYCBPAP PF14646.1 EWM25774.1 - 1.3 7.6 4.9 1.6 7.3 3.4 1.1 1 0 0 1 1 1 0 MYCBP-associated protein family cobW PF02492.14 EWM25776.1 - 9.2e-39 132.7 0.0 1.6e-38 131.9 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EWM25776.1 - 3.9e-12 45.7 0.0 8.3e-11 41.4 0.0 2.4 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain AAA_22 PF13401.1 EWM25776.1 - 0.00072 19.7 0.0 0.0023 18.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 EWM25776.1 - 0.0019 17.9 0.2 0.0055 16.4 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EWM25776.1 - 0.0033 17.7 0.0 0.0068 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EWM25776.1 - 0.011 15.5 0.0 0.053 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EWM25776.1 - 0.013 15.4 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EWM25776.1 - 0.016 14.7 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 EWM25776.1 - 0.02 14.9 0.0 0.046 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Arch_ATPase PF01637.13 EWM25776.1 - 0.025 14.2 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase ATP_bind_1 PF03029.12 EWM25776.1 - 0.038 13.5 0.1 5.2 6.5 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein NACHT PF05729.7 EWM25776.1 - 0.045 13.4 0.1 0.093 12.3 0.1 1.5 1 0 0 1 1 1 0 NACHT domain SRPRB PF09439.5 EWM25776.1 - 0.063 12.5 0.1 0.17 11.1 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_23 PF13476.1 EWM25776.1 - 0.065 13.5 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EWM25776.1 - 0.068 13.1 0.1 0.2 11.6 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_10 PF12846.2 EWM25776.1 - 0.074 12.4 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain DUF258 PF03193.11 EWM25776.1 - 0.091 11.9 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 EWM25776.1 - 0.095 12.2 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TrwB_AAD_bind PF10412.4 EWM25776.1 - 0.099 11.2 0.0 0.16 10.5 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_17 PF13207.1 EWM25776.1 - 0.12 13.2 0.1 0.35 11.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EWM25776.1 - 0.13 11.9 0.3 0.26 10.9 0.2 1.5 1 0 0 1 1 1 0 NTPase RRM_1 PF00076.17 EWM25778.1 - 0.0018 17.8 0.1 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 EWM25778.1 - 0.0071 16.2 28.5 0.018 14.9 2.4 5.1 5 0 0 5 5 5 2 Zinc knuckle zf-CCHC_4 PF14392.1 EWM25778.1 - 0.041 13.5 35.1 0.86 9.3 1.4 5.3 5 0 0 5 5 5 0 Zinc knuckle DUF4449 PF14613.1 EWM25779.1 - 0.00027 20.9 0.0 0.00059 19.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4449) LBP_BPI_CETP PF01273.20 EWM25779.1 - 0.03 13.6 0.0 0.068 12.5 0.0 1.6 1 0 0 1 1 1 0 LBP / BPI / CETP family, N-terminal domain UCH_1 PF13423.1 EWM25779.1 - 0.036 13.5 1.2 0.064 12.6 0.4 1.6 1 1 1 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase PI3_PI4_kinase PF00454.22 EWM25780.1 - 2.4e-30 105.7 0.0 6.9e-29 100.9 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.1 EWM25780.1 - 0.14 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Sugar_tr PF00083.19 EWM25781.1 - 7.6e-99 331.2 21.4 9.1e-99 331.0 14.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EWM25781.1 - 3.1e-35 121.5 26.2 3.3e-24 85.2 4.6 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily OATP PF03137.15 EWM25781.1 - 0.0012 16.9 0.7 0.0012 16.9 0.5 2.6 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family DUF221 PF02714.10 EWM25782.1 - 1.9e-57 194.5 12.8 2.7e-57 194.0 8.9 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EWM25782.1 - 1.6e-27 95.9 2.0 1.6e-27 95.9 1.4 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PPR_2 PF13041.1 EWM25783.1 - 0.00049 20.0 0.0 0.00071 19.4 0.0 1.2 1 0 0 1 1 1 1 PPR repeat family PPR_3 PF13812.1 EWM25783.1 - 0.0015 18.6 0.0 0.0028 17.7 0.0 1.5 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR PF01535.15 EWM25783.1 - 0.024 14.5 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 PPR repeat TAT_signal PF10518.4 EWM25783.1 - 0.13 12.3 4.3 0.32 11.1 2.7 1.9 1 1 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence PPR_2 PF13041.1 EWM25784.1 - 0.00049 20.0 0.0 0.00071 19.4 0.0 1.2 1 0 0 1 1 1 1 PPR repeat family PPR_3 PF13812.1 EWM25784.1 - 0.0015 18.6 0.0 0.0028 17.7 0.0 1.5 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR PF01535.15 EWM25784.1 - 0.024 14.5 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 PPR repeat TAT_signal PF10518.4 EWM25784.1 - 0.13 12.3 4.3 0.32 11.1 2.7 1.9 1 1 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence PPR_2 PF13041.1 EWM25785.1 - 0.00049 20.0 0.0 0.00071 19.4 0.0 1.2 1 0 0 1 1 1 1 PPR repeat family PPR_3 PF13812.1 EWM25785.1 - 0.0015 18.6 0.0 0.0028 17.7 0.0 1.5 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR PF01535.15 EWM25785.1 - 0.024 14.5 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 PPR repeat TAT_signal PF10518.4 EWM25785.1 - 0.13 12.3 4.3 0.32 11.1 2.7 1.9 1 1 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Sfi1_C PF10638.4 EWM25786.1 - 0.0062 16.9 0.0 0.015 15.6 0.0 1.7 1 0 0 1 1 1 1 Spindle body associated protein C-terminus TPX2_importin PF12214.3 EWM25787.1 - 4.2e-05 23.7 3.9 4.2e-05 23.7 2.7 4.2 3 2 1 4 4 4 2 Cell cycle regulated microtubule associated protein ArfGap PF01412.13 EWM25788.1 - 1.1e-32 112.2 0.0 2.5e-32 111.0 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf MR_MLE_N PF02746.11 EWM25788.1 - 0.15 12.0 0.8 0.32 10.9 0.5 1.5 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain STAG PF08514.6 EWM25790.1 - 2.6e-14 52.9 0.0 1.1e-13 50.8 0.0 2.1 2 0 0 2 2 2 1 STAG domain HEAT_2 PF13646.1 EWM25790.1 - 0.0052 17.0 0.4 0.0052 17.0 0.3 5.0 5 1 1 6 6 6 3 HEAT repeats Adaptin_N PF01602.15 EWM25790.1 - 0.022 13.0 0.0 0.045 12.0 0.0 1.4 1 0 0 1 1 1 0 Adaptin N terminal region UPF0020 PF01170.13 EWM25792.1 - 7.5e-33 113.6 0.0 3.5e-30 104.9 0.0 2.3 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.7 EWM25792.1 - 2.6e-14 53.4 0.0 9.2e-14 51.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM25792.1 - 1.4e-12 47.6 0.4 1.4e-08 34.7 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 EWM25792.1 - 4.8e-11 42.6 0.0 2.6e-10 40.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM25792.1 - 3.5e-10 39.6 0.0 2.4e-07 30.4 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM25792.1 - 4.1e-10 40.2 0.2 2.7e-06 27.9 0.0 3.2 3 0 0 3 3 3 2 Methyltransferase domain Ubie_methyltran PF01209.13 EWM25792.1 - 4.3e-10 39.1 0.0 9.3e-10 38.0 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EWM25792.1 - 9.7e-09 35.5 0.0 1.6e-06 28.3 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM25792.1 - 1.1e-06 28.9 0.0 2.6e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EWM25792.1 - 0.045 12.8 0.0 0.37 9.8 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) NIF PF03031.13 EWM25794.1 - 3e-53 179.7 0.1 4.3e-53 179.2 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Dus PF01207.12 EWM25795.1 - 6.2e-57 192.7 0.0 8.5e-57 192.3 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 EWM25795.1 - 0.011 15.0 0.0 0.021 14.0 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein Fcf2 PF08698.6 EWM25797.1 - 4e-14 52.4 0.4 1.3e-13 50.7 0.1 2.0 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing zf-C3HC4_2 PF13923.1 EWM25798.1 - 0.00019 21.3 9.7 0.00043 20.2 6.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF3337 PF11816.3 EWM25798.1 - 0.038 13.3 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) zf-C3HC4 PF00097.20 EWM25798.1 - 0.69 9.6 9.4 1.5 8.5 6.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EWM25798.1 - 7.1 6.5 9.1 18 5.2 6.3 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING mTERF PF02536.9 EWM25799.1 - 1.6e-23 82.8 0.0 3.3e-15 55.5 0.0 3.0 2 1 1 3 3 3 2 mTERF IBV_3A PF03617.8 EWM25799.1 - 1.9 8.2 6.1 0.1 12.3 0.3 1.9 2 0 0 2 2 2 0 IBV 3A protein AMP-binding PF00501.23 EWM25800.1 - 3.9e-71 239.6 0.0 5e-71 239.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EWM25800.1 - 4.7e-12 46.6 0.1 1.3e-11 45.3 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Peroxin-3 PF04882.7 EWM25801.1 - 1.1e-31 110.0 0.0 5.4e-28 97.8 0.0 2.1 1 1 1 2 2 2 2 Peroxin-3 DUF1930 PF09122.5 EWM25802.1 - 0.027 14.2 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1930) MerT PF02411.10 EWM25802.1 - 0.029 14.1 0.2 0.058 13.2 0.1 1.5 1 0 0 1 1 1 0 MerT mercuric transport protein HMA PF00403.21 EWM25802.1 - 0.035 14.2 0.0 0.073 13.2 0.0 1.5 1 0 0 1 1 1 0 Heavy-metal-associated domain Glyco_hydro_8 PF01270.12 EWM25803.1 - 6.2e-27 94.2 7.3 8.9e-27 93.6 5.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 8 MazG PF03819.12 EWM25804.1 - 4.8e-06 26.4 0.0 1.2e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain Cnd1 PF12717.2 EWM25805.1 - 0.0043 16.9 0.0 1.3 8.8 0.0 3.5 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 MMS19_N PF14500.1 EWM25805.1 - 0.0054 16.0 0.0 0.06 12.6 0.0 2.6 2 1 1 3 3 3 2 Dos2-interacting transcription regulator of RNA-Pol-II HEAT PF02985.17 EWM25805.1 - 0.025 14.6 11.8 1.5 9.1 0.0 6.8 7 0 0 7 7 7 0 HEAT repeat Bromodomain PF00439.20 EWM25806.1 - 7.3e-17 61.0 0.0 2.2e-13 49.9 0.0 2.9 2 0 0 2 2 2 2 Bromodomain PHD PF00628.24 EWM25806.1 - 3.3e-09 36.2 28.0 1.1e-07 31.3 7.4 2.8 2 0 0 2 2 2 2 PHD-finger Prok-RING_1 PF14446.1 EWM25806.1 - 0.072 12.8 21.6 0.57 9.9 3.6 3.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 WHIM2 PF15613.1 EWM25806.1 - 0.1 12.5 0.5 0.31 11.0 0.3 1.8 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 2 PHD_2 PF13831.1 EWM25806.1 - 3.4 7.0 18.0 0.12 11.6 1.4 3.4 2 1 0 2 2 2 0 PHD-finger BING4CT PF08149.6 EWM25807.1 - 1.3e-37 127.1 0.0 8.6e-35 118.1 0.0 2.6 2 0 0 2 2 2 2 BING4CT (NUC141) domain WD40 PF00400.27 EWM25807.1 - 4.5e-10 39.0 0.0 1.2e-06 28.2 0.0 4.7 5 0 0 5 5 5 1 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EWM25807.1 - 0.0024 16.2 0.7 1.6 6.9 0.0 2.8 3 0 0 3 3 3 2 Cytochrome D1 heme domain Mur_ligase_M PF08245.7 EWM25809.1 - 7.1e-06 26.2 0.0 0.0035 17.3 0.0 3.2 2 1 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.16 EWM25809.1 - 0.0037 17.2 0.0 0.008 16.1 0.0 1.6 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain DUF4112 PF13430.1 EWM25810.1 - 0.012 15.5 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4112) Radical_SAM PF04055.16 EWM25811.1 - 4.5e-05 23.6 0.0 7.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 EWM25811.1 - 0.00032 20.7 0.0 0.0006 19.8 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 EWM25811.1 - 0.024 14.7 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain BRCT PF00533.21 EWM25812.1 - 1.1e-09 38.3 0.0 0.0058 16.7 0.0 3.4 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain zf-RanBP PF00641.13 EWM25812.1 - 0.0016 17.4 2.9 0.0042 16.1 2.0 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RTC PF01137.16 EWM25814.1 - 4.2e-65 218.7 0.0 4.7e-65 218.5 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EWM25814.1 - 2.2e-32 111.1 0.0 4.6e-32 110.1 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Tubulin PF00091.20 EWM25815.1 - 5.8e-65 219.1 0.0 8.2e-65 218.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EWM25815.1 - 6.5e-51 171.6 0.1 9.5e-51 171.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EWM25815.1 - 0.0072 15.8 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Utp12 PF04003.7 EWM25816.1 - 1.1e-15 57.4 0.1 1.7e-15 56.8 0.1 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.27 EWM25816.1 - 2.7e-07 30.1 1.0 0.00027 20.6 0.1 4.6 4 0 0 4 4 4 1 WD domain, G-beta repeat eIF2A PF08662.6 EWM25816.1 - 0.055 13.1 0.0 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A zf-RING_2 PF13639.1 EWM25817.1 - 8.6e-05 22.2 7.5 0.00021 21.0 5.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EWM25817.1 - 0.00019 21.5 3.9 0.00064 19.7 2.7 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EWM25817.1 - 0.004 16.9 1.7 0.012 15.4 1.2 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger C1_1 PF00130.17 EWM25817.1 - 0.0065 16.1 1.0 0.0065 16.1 0.7 1.8 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4 PF00097.20 EWM25817.1 - 0.016 14.8 8.8 0.037 13.6 6.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EWM25817.1 - 0.019 14.8 4.6 0.061 13.2 3.2 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 EWM25817.1 - 0.15 12.1 12.9 0.035 14.1 6.1 2.1 2 0 0 2 2 2 0 RING-variant domain zf-C3HC4_3 PF13920.1 EWM25817.1 - 3.1 7.5 6.5 9.4 6.0 4.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.27 EWM25818.1 - 1.9e-23 81.4 6.7 7.2e-06 25.6 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ_3 PF13570.1 EWM25818.1 - 0.0031 17.7 0.0 1.2 9.5 0.0 3.5 4 0 0 4 4 4 2 PQQ-like domain WD40 PF00400.27 EWM25820.1 - 7.4e-15 54.1 6.5 0.0017 18.1 0.2 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat PQQ_2 PF13360.1 EWM25820.1 - 0.0058 16.1 0.1 0.3 10.4 0.0 2.9 2 1 0 2 2 2 1 PQQ-like domain Cyt-b5 PF00173.23 EWM25821.1 - 7.7e-21 73.6 0.0 1.6e-20 72.7 0.0 1.5 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain PAPS_reduct PF01507.14 EWM25822.1 - 6e-37 127.1 0.0 8.5e-37 126.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family PRP38 PF03371.10 EWM25823.1 - 1.3e-62 210.4 0.2 1.7e-62 210.0 0.1 1.1 1 0 0 1 1 1 1 PRP38 family Nop25 PF09805.4 EWM25824.1 - 0.021 14.9 1.3 0.052 13.6 0.9 1.6 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) TauD PF02668.11 EWM25825.1 - 2.2e-52 178.3 0.1 2.9e-52 177.9 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family COG4 PF08318.7 EWM25826.1 - 7.2e-06 24.9 0.0 3.9e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 COG4 transport protein Filaggrin PF03516.8 EWM25826.1 - 0.018 15.4 0.8 0.049 14.0 0.6 1.7 1 0 0 1 1 1 0 Filaggrin COG4 PF08318.7 EWM25827.1 - 8.6e-06 24.7 1.1 2.7e-05 23.0 0.0 2.3 3 0 0 3 3 3 1 COG4 transport protein Filaggrin PF03516.8 EWM25827.1 - 0.038 14.4 0.8 0.038 14.4 0.6 2.0 2 0 0 2 2 2 0 Filaggrin DUF2984 PF11203.3 EWM25827.1 - 0.067 13.2 0.2 1.3 9.2 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2984) UCR_TM PF02921.9 EWM25828.1 - 9.5e-17 60.9 0.3 9.5e-17 60.9 0.2 1.6 2 0 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 EWM25828.1 - 3.7e-16 58.4 0.1 6.4e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DUF4286 PF14114.1 EWM25829.1 - 8.3e-17 61.2 0.1 1.4e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4286) 2OG-FeII_Oxy_3 PF13640.1 EWM25829.1 - 0.011 16.2 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF4286 PF14114.1 EWM25830.1 - 8.3e-17 61.2 0.1 1.4e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4286) 2OG-FeII_Oxy_3 PF13640.1 EWM25830.1 - 0.011 16.2 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily tRNA-synt_2b PF00587.20 EWM25831.1 - 1e-38 132.6 0.0 1.9e-38 131.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EWM25831.1 - 9.6e-17 60.9 5.0 1.5e-16 60.3 3.5 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF615 PF04751.9 EWM25831.1 - 0.0013 18.3 3.0 0.0015 18.2 0.7 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF615) Stathmin PF00836.14 EWM25831.1 - 0.029 14.0 1.4 0.07 12.7 1.0 1.6 1 0 0 1 1 1 0 Stathmin family OmpH PF03938.9 EWM25831.1 - 0.88 9.4 7.2 1.5 8.7 5.0 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) UQ_con PF00179.21 EWM25832.1 - 9e-48 161.2 0.1 1e-47 161.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EWM25832.1 - 2.8e-05 23.8 0.0 3.9e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EWM25832.1 - 0.029 14.0 0.1 0.049 13.3 0.1 1.4 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 EWM25832.1 - 0.12 12.3 0.1 0.14 12.0 0.1 1.4 1 1 0 1 1 1 0 RWD domain ABC_tran PF00005.22 EWM25833.1 - 4.3e-47 159.8 1.0 1.2e-24 87.1 0.0 3.2 4 0 0 4 4 3 2 ABC transporter AAA_21 PF13304.1 EWM25833.1 - 2.3e-23 83.5 0.0 2.6e-05 24.3 0.0 4.3 4 0 0 4 4 4 4 AAA domain ABC_tran_2 PF12848.2 EWM25833.1 - 3.7e-22 77.9 1.4 3.7e-22 77.9 1.0 3.6 4 0 0 4 4 3 1 ABC transporter SMC_N PF02463.14 EWM25833.1 - 6.8e-14 51.6 0.5 3.6e-07 29.6 0.0 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EWM25833.1 - 2e-08 33.6 1.5 0.003 17.0 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EWM25833.1 - 3e-07 30.9 8.5 0.0072 16.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.1 EWM25833.1 - 7.9e-07 28.4 0.0 0.59 9.1 0.0 4.2 4 0 0 4 4 4 1 AAA ATPase domain AAA_25 PF13481.1 EWM25833.1 - 1.1e-06 28.1 0.3 0.0078 15.6 0.0 3.1 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EWM25833.1 - 2e-05 23.8 0.4 0.017 14.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_30 PF13604.1 EWM25833.1 - 8.6e-05 22.2 0.8 0.2 11.2 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EWM25833.1 - 9.5e-05 22.4 7.9 0.053 13.4 0.0 3.5 5 0 0 5 5 3 2 AAA domain MMR_HSR1 PF01926.18 EWM25833.1 - 0.00014 21.7 0.0 0.45 10.4 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 EWM25833.1 - 0.00016 22.1 0.0 0.33 11.4 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 EWM25833.1 - 0.00024 21.8 2.5 0.44 11.3 0.0 3.5 5 0 0 5 5 2 2 AAA domain SbcCD_C PF13558.1 EWM25833.1 - 0.00028 20.7 3.8 0.17 11.7 0.1 4.0 3 1 0 3 3 3 1 Putative exonuclease SbcCD, C subunit ArgK PF03308.11 EWM25833.1 - 0.00037 19.3 3.7 0.082 11.6 0.2 2.9 3 0 0 3 3 3 2 ArgK protein AAA_22 PF13401.1 EWM25833.1 - 0.00058 19.9 1.0 0.22 11.6 0.2 3.6 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EWM25833.1 - 0.00082 19.4 5.8 0.056 13.4 0.0 3.4 2 1 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.18 EWM25833.1 - 0.002 17.9 4.8 0.56 10.0 0.0 3.4 3 0 0 3 3 3 1 Dynamin family AAA_19 PF13245.1 EWM25833.1 - 0.0046 16.6 3.3 2.7 7.8 0.1 3.6 3 0 0 3 3 3 1 Part of AAA domain AAA PF00004.24 EWM25833.1 - 0.0059 16.7 0.3 0.15 12.2 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EWM25833.1 - 0.0089 15.9 0.0 1.7 8.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain Mg_chelatase PF01078.16 EWM25833.1 - 0.011 14.8 0.8 0.1 11.7 0.0 2.5 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EWM25833.1 - 0.018 15.3 0.1 3.5 7.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EWM25833.1 - 0.018 14.4 0.9 2.9 7.2 0.1 2.5 2 0 0 2 2 2 0 AAA-like domain RNA_helicase PF00910.17 EWM25833.1 - 0.025 14.7 0.2 0.88 9.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.13 EWM25833.1 - 0.027 13.9 5.8 2.5 7.5 0.4 3.3 3 0 0 3 3 3 0 FtsK/SpoIIIE family Arf PF00025.16 EWM25833.1 - 0.029 13.5 0.1 3.8 6.7 0.0 2.6 2 0 0 2 2 2 0 ADP-ribosylation factor family ATP-synt_ab PF00006.20 EWM25833.1 - 0.054 12.9 7.4 0.62 9.5 0.5 2.6 2 2 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Rad17 PF03215.10 EWM25833.1 - 0.067 11.8 0.8 0.11 11.1 0.1 1.6 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein DAP3 PF10236.4 EWM25833.1 - 0.09 11.6 1.7 1.1 8.0 0.1 2.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.7 EWM25833.1 - 0.097 12.3 2.3 1.5 8.4 0.0 2.7 3 0 0 3 3 2 0 NACHT domain AAA_13 PF13166.1 EWM25833.1 - 0.12 10.8 2.7 14 3.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.1 EWM25833.1 - 0.18 11.3 1.8 0.64 9.5 0.1 2.5 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.9 EWM25833.1 - 0.26 11.0 2.6 1.1 9.0 0.1 3.1 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) Prefoldin_2 PF01920.15 EWM25833.1 - 0.3 10.8 3.9 12 5.6 0.7 2.6 2 0 0 2 2 2 0 Prefoldin subunit AAA_33 PF13671.1 EWM25833.1 - 0.56 10.0 7.7 1.1 9.1 0.2 3.9 4 1 0 4 4 4 0 AAA domain Arch_ATPase PF01637.13 EWM25833.1 - 1.3 8.7 3.6 0.94 9.1 0.0 2.5 4 0 0 4 4 3 0 Archaeal ATPase G-alpha PF00503.15 EWM25833.1 - 1.5 7.4 3.7 1.5 7.4 0.1 2.5 2 1 0 3 3 2 0 G-protein alpha subunit Mnd1 PF03962.10 EWM25833.1 - 6.4 6.4 9.4 7.1 6.2 1.9 2.3 2 0 0 2 2 2 0 Mnd1 family 2OG-FeII_Oxy PF03171.15 EWM25834.1 - 1.5e-06 28.3 0.0 1.2e-05 25.5 0.0 2.4 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily PDZ_1 PF12812.2 EWM25835.1 - 1.5e-15 56.7 0.0 3.2e-07 30.1 0.0 2.6 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.1 EWM25835.1 - 6.3e-12 45.5 0.0 1.7e-11 44.1 0.0 1.8 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 EWM25835.1 - 2.1e-11 43.5 0.0 2e-06 27.5 0.0 4.7 4 1 0 4 4 4 1 PDZ domain PDZ PF00595.19 EWM25835.1 - 1.3e-06 28.5 0.0 0.95 9.6 0.0 4.4 4 0 0 4 4 4 2 PDZ domain (Also known as DHR or GLGF) Tricorn_PDZ PF14685.1 EWM25835.1 - 0.00011 21.9 0.0 0.11 12.2 0.0 3.4 3 0 0 3 3 3 1 Tricorn protease PDZ domain Peptidase_S7 PF00949.16 EWM25835.1 - 0.046 13.1 0.1 0.099 12.0 0.1 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.11 EWM25835.1 - 0.31 10.3 0.2 0.46 9.7 0.2 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) DUF482 PF04339.7 EWM25836.1 - 1.5e-118 395.8 0.0 1.8e-118 395.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF482 Acetyltransf_6 PF13480.1 EWM25836.1 - 3.2e-08 33.6 0.0 6.7e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Fe-ADH PF00465.14 EWM25837.1 - 2.2e-46 158.1 0.0 4.3e-46 157.2 0.0 1.4 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase CMD PF02627.15 EWM25837.1 - 4.4e-05 23.2 0.0 8.9e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Fe-ADH_2 PF13685.1 EWM25837.1 - 0.0019 17.5 0.0 0.092 12.0 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Misat_Tub_SegII PF10644.4 EWM25838.1 - 2e-14 53.5 0.0 3.3e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 EWM25838.1 - 0.0016 18.3 0.0 0.017 14.9 0.0 2.0 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain BRO1 PF03097.13 EWM25840.1 - 1.6e-82 277.3 1.3 2.6e-82 276.5 0.9 1.3 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EWM25840.1 - 7.8e-31 107.1 9.4 7.8e-31 107.1 6.5 2.4 3 0 0 3 3 3 1 ALIX V-shaped domain binding to HIV UBA PF00627.26 EWM25840.1 - 0.0014 18.3 0.3 0.0063 16.3 0.1 2.3 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.1 EWM25840.1 - 0.031 13.7 0.8 0.13 11.8 0.1 2.2 2 0 0 2 2 2 0 UBA-like domain CUE PF02845.11 EWM25840.1 - 0.077 12.4 0.2 4 7.0 0.0 2.9 3 0 0 3 3 3 0 CUE domain RRM_1 PF00076.17 EWM25841.1 - 5e-39 131.7 0.0 2.3e-19 68.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM25841.1 - 7.3e-24 83.5 0.0 1.5e-11 44.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM25841.1 - 2.6e-20 72.0 0.0 2.2e-10 40.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EWM25841.1 - 0.00018 20.9 0.3 0.0097 15.3 0.0 2.4 2 0 0 2 2 2 1 Ribonuclease B OB domain Limkain-b1 PF11608.3 EWM25841.1 - 0.00072 19.2 0.0 0.041 13.6 0.0 2.4 2 0 0 2 2 2 1 Limkain b1 UPF0047 PF01894.12 EWM25842.1 - 4.6e-35 119.9 0.0 5.2e-35 119.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 AAA_2 PF07724.9 EWM25843.1 - 2e-40 138.5 0.1 8.6e-33 113.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 EWM25843.1 - 4.7e-14 52.7 0.1 3.9e-06 27.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EWM25843.1 - 1.3e-07 31.3 0.6 3.7e-07 29.9 0.4 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EWM25843.1 - 9e-07 28.7 0.0 0.00019 21.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EWM25843.1 - 6.2e-05 22.9 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EWM25843.1 - 9.8e-05 21.5 0.4 0.0038 16.3 0.0 2.5 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EWM25843.1 - 0.00019 22.2 0.0 0.00052 20.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EWM25843.1 - 0.00021 21.4 0.2 0.0046 17.1 0.0 3.1 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 EWM25843.1 - 0.00024 21.1 0.1 0.00067 19.6 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 EWM25843.1 - 0.00036 19.6 0.0 0.00065 18.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin MCM PF00493.18 EWM25843.1 - 0.00043 19.1 0.0 0.007 15.2 0.0 2.1 2 0 0 2 2 2 1 MCM2/3/5 family Mg_chelatase PF01078.16 EWM25843.1 - 0.00046 19.4 0.1 0.0066 15.6 0.0 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI ATP-synt_ab PF00006.20 EWM25843.1 - 0.0011 18.4 0.0 0.0024 17.3 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain TIP49 PF06068.8 EWM25843.1 - 0.0023 16.7 0.1 0.0048 15.6 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_18 PF13238.1 EWM25843.1 - 0.0027 17.9 0.1 0.016 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 EWM25843.1 - 0.0028 17.1 0.0 0.026 14.0 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain G-alpha PF00503.15 EWM25843.1 - 0.0036 16.0 0.0 0.0058 15.3 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit Arch_ATPase PF01637.13 EWM25843.1 - 0.011 15.4 0.4 0.2 11.3 0.1 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA_14 PF13173.1 EWM25843.1 - 0.014 15.2 0.0 1 9.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EWM25843.1 - 0.039 14.2 0.0 0.09 13.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 EWM25843.1 - 0.042 13.3 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation CPT PF07931.7 EWM25843.1 - 0.066 12.8 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein NACHT PF05729.7 EWM25843.1 - 0.068 12.8 0.0 1.9 8.1 0.0 2.6 2 1 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.12 EWM25843.1 - 0.098 12.0 0.0 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.1 EWM25843.1 - 0.11 12.4 0.1 0.51 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 EWM25843.1 - 0.11 11.9 0.1 0.49 9.8 0.0 2.0 2 1 0 3 3 2 0 DEAD/DEAH box helicase Sigma54_activ_2 PF14532.1 EWM25843.1 - 0.13 12.3 0.0 2.4 8.1 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF726 PF05277.7 EWM25844.1 - 1.8e-82 277.0 5.3 9.8e-36 123.3 0.1 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF726) Abhydrolase_5 PF12695.2 EWM25844.1 - 0.0017 18.1 0.0 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 EWM25844.1 - 0.066 12.5 0.0 0.17 11.1 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF3730 PF12530.3 EWM25845.1 - 3.2e-09 37.0 0.2 3.2e-09 37.0 0.1 4.3 5 1 0 5 5 5 1 Protein of unknown function (DUF3730) Methyltransf_31 PF13847.1 EWM25846.1 - 4.8e-31 107.4 0.0 7.9e-31 106.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM25846.1 - 2.4e-19 69.6 0.0 4.9e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EWM25846.1 - 3.6e-13 49.1 0.0 5.5e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EWM25846.1 - 9.1e-13 48.7 0.0 1.7e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM25846.1 - 3.2e-11 43.4 0.0 8e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM25846.1 - 2.9e-10 40.1 0.1 7.7e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM25846.1 - 3.4e-10 40.2 0.0 7.6e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM25846.1 - 5.7e-10 39.1 0.0 9.6e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EWM25846.1 - 4.9e-06 26.2 0.1 9.6e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.10 EWM25846.1 - 9.7e-06 25.3 0.1 3e-05 23.7 0.0 1.8 1 1 0 2 2 2 1 Hypothetical methyltransferase PrmA PF06325.8 EWM25846.1 - 0.00019 20.6 0.0 0.00045 19.4 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) GCD14 PF08704.5 EWM25846.1 - 0.077 12.4 0.1 0.16 11.4 0.1 1.5 1 1 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit MTS PF05175.9 EWM25846.1 - 0.16 11.3 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain HECT PF00632.20 EWM25847.1 - 1e-78 264.6 0.0 1.3e-78 264.3 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Glyco_hydro_63 PF03200.11 EWM25850.1 - 1.9e-193 644.5 0.0 2.8e-193 644.0 0.0 1.2 1 0 0 1 1 1 1 Mannosyl oligosaccharide glucosidase GDE_C PF06202.9 EWM25850.1 - 0.044 12.4 0.1 0.12 11.1 0.1 1.5 2 0 0 2 2 2 0 Amylo-alpha-1,6-glucosidase Trehalase PF01204.13 EWM25850.1 - 0.046 12.3 0.0 0.085 11.4 0.0 1.3 1 0 0 1 1 1 0 Trehalase RNA_pol_I_TF PF04090.7 EWM25850.1 - 0.48 9.6 1.1 7.6 5.7 0.1 2.3 2 0 0 2 2 2 0 RNA polymerase I specific initiation factor ACT_6 PF13740.1 EWM25851.1 - 5.5e-13 48.4 0.0 9.6e-12 44.4 0.0 2.3 2 0 0 2 2 2 1 ACT domain ACT PF01842.20 EWM25851.1 - 2.1e-08 33.4 0.0 0.00046 19.6 0.0 2.5 2 0 0 2 2 2 2 ACT domain ACT_4 PF13291.1 EWM25851.1 - 0.00087 19.5 0.0 0.29 11.5 0.0 2.3 2 0 0 2 2 2 2 ACT domain Ribophorin_I PF04597.9 EWM25852.1 - 3.6e-98 328.8 0.0 4.4e-98 328.6 0.0 1.1 1 0 0 1 1 1 1 Ribophorin I cwf18 PF08315.7 EWM25853.1 - 4.8e-19 69.0 6.5 1.8e-17 63.9 4.5 2.2 1 1 0 1 1 1 1 cwf18 pre-mRNA splicing factor PRCC PF10253.4 EWM25853.1 - 0.075 13.7 4.0 0.087 13.5 2.8 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting PC_rep PF01851.17 EWM25854.1 - 7.8e-30 101.4 24.1 1.6e-06 27.9 0.1 9.2 9 0 0 9 9 9 7 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EWM25854.1 - 4e-16 59.0 10.3 1.8e-09 37.7 0.1 4.7 2 1 1 4 4 4 4 HEAT repeats HEAT PF02985.17 EWM25854.1 - 1.9e-06 27.4 2.2 6.9 7.0 0.1 5.7 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 EWM25854.1 - 0.00075 19.9 17.0 0.017 15.5 0.1 6.8 4 2 5 9 9 9 3 HEAT-like repeat WD40 PF00400.27 EWM25855.1 - 3.4e-24 83.7 18.1 1.3e-07 31.1 0.1 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat ATG16 PF08614.6 EWM25855.1 - 4.2e-14 52.8 18.7 6.6e-14 52.1 13.0 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF342 PF03961.8 EWM25855.1 - 1.3 7.3 13.1 0.04 12.3 2.5 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 EWM25855.1 - 1.8 6.2 9.4 3 5.5 6.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc42p PF11544.3 EWM25855.1 - 2.1 8.3 11.2 3.6 7.5 0.3 4.3 4 1 1 5 5 5 0 Spindle pole body component Spc42p CENP-H PF05837.7 EWM25855.1 - 2.7 8.1 18.0 0.044 13.9 4.1 2.5 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Semialdhyde_dh PF01118.19 EWM25857.1 - 1.6e-26 93.0 0.0 2.5e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.13 EWM25857.1 - 1.5e-18 67.3 0.0 2.2e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain S1 PF00575.18 EWM25858.1 - 0.011 15.7 0.1 2.5 8.2 0.0 2.6 2 0 0 2 2 2 0 S1 RNA binding domain XPC-binding PF09280.6 EWM25859.1 - 2.7e-16 58.7 5.1 2.7e-16 58.7 3.5 2.6 2 0 0 2 2 2 1 XPC-binding domain UBA PF00627.26 EWM25859.1 - 1e-13 50.6 6.8 1.1e-06 28.3 1.3 2.7 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.18 EWM25859.1 - 3e-12 45.7 0.4 5.8e-12 44.8 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 EWM25859.1 - 1.7e-07 30.7 0.4 4.2e-07 29.5 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.5 EWM25859.1 - 0.0003 20.2 0.1 2 8.1 0.0 3.3 3 0 0 3 3 3 2 Fungal ubiquitin-associated domain FeoC PF09012.5 EWM25859.1 - 0.087 12.5 0.3 0.31 10.7 0.0 2.0 2 0 0 2 2 2 0 FeoC like transcriptional regulator DUF2407 PF10302.4 EWM25859.1 - 0.12 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF3135 PF11333.3 EWM25859.1 - 0.21 11.7 4.6 0.26 11.4 0.0 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF3135) Thioredoxin PF00085.15 EWM25860.1 - 1.1e-08 34.6 0.1 2.1e-08 33.7 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 EWM25860.1 - 2.6e-06 26.3 0.6 3.3e-06 26.0 0.4 1.1 1 0 0 1 1 1 1 Phosducin DUF445 PF04286.7 EWM25860.1 - 0.038 13.5 0.7 0.04 13.4 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) COX16 PF14138.1 EWM25860.1 - 0.16 12.1 1.4 0.35 11.0 1.0 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 DNA_pol_alpha_N PF12254.3 EWM25860.1 - 1.2 8.9 6.0 5.8 6.8 0.1 2.8 2 1 1 3 3 3 0 DNA polymerase alpha subunit p180 N terminal AGTRAP PF06396.6 EWM25861.1 - 0.031 13.9 0.2 0.04 13.5 0.2 1.2 1 0 0 1 1 1 0 Angiotensin II, type I receptor-associated protein (AGTRAP) DUF3523 PF12037.3 EWM25862.1 - 1.5e-65 220.9 36.3 2.3e-65 220.3 25.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) AAA PF00004.24 EWM25862.1 - 8.7e-22 77.7 0.0 1.9e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EWM25862.1 - 0.00034 21.4 0.0 0.00034 21.4 0.0 2.9 2 1 0 2 2 1 1 AAA domain AAA_22 PF13401.1 EWM25862.1 - 0.00038 20.6 8.0 0.055 13.6 0.0 3.4 2 2 1 3 3 2 2 AAA domain AAA_5 PF07728.9 EWM25862.1 - 0.00047 19.8 3.1 0.078 12.7 0.1 3.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EWM25862.1 - 0.00082 18.8 0.0 0.0019 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EWM25862.1 - 0.0011 18.8 2.4 0.0012 18.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EWM25862.1 - 0.0025 17.0 0.2 0.013 14.6 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EWM25862.1 - 0.0026 17.2 0.1 0.0075 15.7 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EWM25862.1 - 0.0029 17.3 3.4 0.01 15.5 0.1 2.9 2 0 0 2 2 2 1 Part of AAA domain RuvB_N PF05496.7 EWM25862.1 - 0.0029 16.6 0.0 0.0064 15.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus KaiC PF06745.8 EWM25862.1 - 0.0044 16.1 0.5 0.075 12.1 0.0 2.3 2 0 0 2 2 2 1 KaiC Zot PF05707.7 EWM25862.1 - 0.012 15.1 2.8 0.073 12.5 0.1 2.7 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_16 PF13191.1 EWM25862.1 - 0.012 15.5 0.0 0.012 15.5 0.0 3.6 2 2 1 3 3 2 0 AAA ATPase domain Sigma54_activ_2 PF14532.1 EWM25862.1 - 0.018 15.0 0.0 0.25 11.3 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain UPF0079 PF02367.12 EWM25862.1 - 0.045 13.3 0.8 0.16 11.6 0.0 2.2 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 EWM25862.1 - 0.15 12.2 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.1 EWM25862.1 - 0.4 10.2 0.0 0.4 10.2 0.0 3.1 2 1 0 2 2 1 0 AAA domain Cyclin_N PF00134.18 EWM25863.1 - 3.1e-49 165.7 1.4 6.4e-45 151.8 0.1 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 EWM25863.1 - 1.4e-29 102.3 0.7 2.9e-29 101.3 0.5 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain WD40 PF00400.27 EWM25864.1 - 6.3e-08 32.2 0.2 1.2e-05 24.9 0.2 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat Peptidase_M16 PF00675.15 EWM25865.1 - 1e-25 90.2 0.7 1.6e-25 89.6 0.1 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EWM25865.1 - 1.7e-22 79.9 0.0 2.9e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Fer4_15 PF13459.1 EWM25866.1 - 1.1e-17 64.3 2.7 1.8e-17 63.6 1.1 2.1 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_13 PF13370.1 EWM25866.1 - 3.8e-16 59.2 2.2 1.1e-15 57.7 1.5 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_21 PF14697.1 EWM25866.1 - 0.0031 17.3 1.8 0.0031 17.3 1.3 2.1 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EWM25866.1 - 0.0092 16.2 2.9 0.0092 16.2 2.0 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_19 PF06902.6 EWM25866.1 - 0.014 15.1 0.6 0.014 15.1 0.4 2.0 2 0 0 2 2 2 0 Divergent 4Fe-4S mono-cluster Fer4_10 PF13237.1 EWM25866.1 - 0.018 14.8 5.6 0.081 12.7 0.3 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 EWM25866.1 - 0.068 13.1 0.7 0.068 13.1 0.5 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain zf-U11-48K PF05253.7 EWM25866.1 - 0.086 12.5 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 U11-48K-like CHHC zinc finger Fer4_7 PF12838.2 EWM25866.1 - 0.096 13.0 8.4 0.34 11.3 0.6 2.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Adaptin_N PF01602.15 EWM25868.1 - 7.7e-126 420.4 1.2 9.7e-126 420.1 0.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EWM25868.1 - 2e-19 70.0 0.0 3.6e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 EWM25868.1 - 3.5e-09 36.8 7.1 0.0026 17.9 0.0 5.0 3 1 2 5 5 5 4 HEAT repeats Cnd1 PF12717.2 EWM25868.1 - 1.7e-07 31.2 0.6 5e-05 23.2 0.0 2.7 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EWM25868.1 - 2.3e-06 27.1 1.4 0.077 13.1 0.0 6.0 6 0 0 6 6 6 1 HEAT repeat DUF2435 PF10363.4 EWM25868.1 - 0.011 15.6 1.1 0.28 11.0 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) CLASP_N PF12348.3 EWM25868.1 - 0.016 14.5 0.2 3 7.1 0.0 2.5 2 0 0 2 2 2 0 CLASP N terminal RasGEF_N_2 PF14663.1 EWM25868.1 - 0.039 13.8 0.6 15 5.5 0.1 3.0 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Vac14_Fab1_bd PF12755.2 EWM25868.1 - 0.073 13.4 0.5 15 6.0 0.0 3.2 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region Exo70 PF03081.10 EWM25868.1 - 0.079 11.7 0.1 0.16 10.7 0.1 1.6 1 1 0 1 1 1 0 Exo70 exocyst complex subunit TIP120 PF08623.5 EWM25868.1 - 0.15 11.5 0.9 2.4 7.7 0.1 2.5 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) MMS19_N PF14500.1 EWM25868.1 - 0.27 10.4 2.1 59 2.7 0.0 3.8 4 1 1 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II Glyco_hydro_9 PF00759.14 EWM25871.1 - 2.8e-123 412.1 2.7 3.2e-123 411.9 1.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Reo_sigmaC PF04582.7 EWM25872.1 - 0.26 10.4 1.8 0.35 9.9 1.2 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Mito_carr PF00153.22 EWM25873.1 - 1.1e-60 201.3 5.7 3.2e-26 90.8 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein ubiquitin PF00240.18 EWM25874.1 - 5.2e-08 32.1 0.2 1.3e-07 30.8 0.2 1.6 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EWM25874.1 - 4.4e-05 23.6 0.1 0.00015 21.9 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.3 EWM25874.1 - 0.0074 15.9 0.1 0.025 14.2 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Frataxin_Cyay PF01491.11 EWM25875.1 - 0.0059 16.3 0.0 0.0085 15.8 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain DEAD PF00270.24 EWM25876.1 - 2.4e-46 157.3 0.0 1.9e-45 154.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EWM25876.1 - 6.5e-28 96.4 0.0 1.8e-27 95.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EWM25876.1 - 0.016 15.0 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EWM25876.1 - 0.1 10.9 0.1 0.37 9.1 0.0 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1253) Adaptin_N PF01602.15 EWM25877.1 - 4e-155 517.1 10.4 4.8e-155 516.8 7.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EWM25877.1 - 6.2e-33 114.1 0.5 1.4e-29 103.2 0.0 3.7 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EWM25877.1 - 2.7e-21 75.6 5.0 3.1e-09 36.9 0.2 5.9 1 1 5 6 6 6 5 HEAT repeats B2-adapt-app_C PF09066.5 EWM25877.1 - 3.2e-13 49.5 0.0 6.7e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_EZ PF13513.1 EWM25877.1 - 1.2e-09 38.4 6.0 0.095 13.2 0.3 6.2 5 0 0 5 5 5 3 HEAT-like repeat HEAT PF02985.17 EWM25877.1 - 1.8e-08 33.7 6.1 0.019 15.0 0.1 5.3 5 0 0 5 5 5 2 HEAT repeat Arm PF00514.18 EWM25877.1 - 8e-05 22.3 2.1 0.53 10.1 0.0 4.9 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Alpha_adaptinC2 PF02883.15 EWM25877.1 - 0.0028 17.9 0.0 0.0069 16.7 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain CLASP_N PF12348.3 EWM25877.1 - 0.0043 16.4 1.1 2.1 7.6 0.0 3.2 3 1 0 3 3 3 2 CLASP N terminal DUF3915 PF13054.1 EWM25877.1 - 0.02 14.8 0.1 0.037 13.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) UNC45-central PF11701.3 EWM25877.1 - 0.052 13.1 1.4 1.7 8.2 0.0 3.0 3 1 0 3 3 3 0 Myosin-binding striated muscle assembly central HEAT_PBS PF03130.11 EWM25877.1 - 0.59 10.7 3.4 32 5.3 0.1 4.4 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat DUF4282 PF14110.1 EWM25878.1 - 0.0028 17.7 13.9 0.0041 17.2 9.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4282) IncA PF04156.9 EWM25878.1 - 0.17 11.4 5.2 0.28 10.7 3.6 1.3 1 0 0 1 1 1 0 IncA protein Bac_rhamnosid_N PF08531.5 EWM25879.1 - 0.0014 18.1 2.4 1.4 8.4 0.1 3.5 3 1 0 3 3 3 2 Alpha-L-rhamnosidase N-terminal domain Ank_2 PF12796.2 EWM25880.1 - 2.7e-09 37.2 0.0 7.2e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EWM25880.1 - 7.8e-09 35.5 0.3 4.5e-05 23.5 0.0 3.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EWM25880.1 - 8.2e-07 28.5 0.0 0.0089 15.7 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EWM25880.1 - 1.5e-05 25.3 0.1 0.0053 17.2 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM25880.1 - 3.1e-05 23.7 0.0 0.012 15.7 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Metallophos PF00149.23 EWM25881.1 - 4.3e-07 29.5 0.2 6.3e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.23 EWM25882.1 - 8.4e-21 74.2 1.8 1.1e-20 73.8 1.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EWM25882.1 - 2.8e-05 24.0 0.1 5.6e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Cupin_7 PF12973.2 EWM25883.1 - 0.0073 16.1 0.0 0.94 9.3 0.0 2.3 2 0 0 2 2 2 2 ChrR Cupin-like domain GNAT_acetyltr_2 PF13718.1 EWM25885.1 - 1.4e-74 249.6 0.0 2.2e-74 249.0 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EWM25885.1 - 2.1e-61 206.6 0.0 3.9e-61 205.7 0.0 1.5 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.6 EWM25885.1 - 7.3e-39 131.3 0.1 2e-38 129.9 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EWM25885.1 - 3.6e-21 75.1 0.1 1.2e-20 73.4 0.0 1.9 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 EWM25885.1 - 0.012 15.8 0.0 0.034 14.2 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EWM25885.1 - 0.018 15.0 0.0 0.058 13.4 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family G6PD_C PF02781.11 EWM25886.1 - 1.3e-111 372.1 0.0 1.7e-111 371.7 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EWM25886.1 - 3.6e-58 196.8 0.0 4.8e-58 196.4 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF4648 PF15505.1 EWM25887.1 - 8 6.6 8.6 13 5.9 0.6 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4648) TPR_16 PF13432.1 EWM25890.1 - 1.5e-07 31.8 20.7 0.0051 17.4 0.9 5.7 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 EWM25890.1 - 2.9e-06 27.4 22.7 0.0014 19.1 1.5 7.3 6 1 2 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.12 EWM25890.1 - 0.0027 17.4 3.3 0.067 13.1 0.3 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EWM25890.1 - 0.01 15.4 0.1 0.76 9.4 0.1 3.7 3 1 1 4 4 4 0 TPR repeat Stk19 PF10494.4 EWM25891.1 - 1.1e-20 74.1 0.4 1.1e-19 70.8 0.3 2.2 1 1 0 1 1 1 1 Serine-threonine protein kinase 19 DUF4279 PF14106.1 EWM25892.1 - 0.097 12.5 3.1 4 7.3 0.0 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4279) AAA_13 PF13166.1 EWM25892.1 - 0.32 9.3 12.2 0.012 14.0 3.3 2.0 2 0 0 2 2 2 0 AAA domain Sec6 PF06046.8 EWM25893.1 - 9.6e-14 50.3 0.0 6.2e-07 27.8 0.0 2.7 2 1 0 2 2 2 2 Exocyst complex component Sec6 ADIP PF11559.3 EWM25893.1 - 0.0024 17.7 2.3 0.006 16.4 1.6 1.7 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding RCC1 PF00415.13 EWM25894.1 - 2.7e-38 129.9 39.4 1.6e-11 44.2 0.7 8.7 8 2 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EWM25894.1 - 4.4e-28 96.2 48.1 2e-07 30.4 0.5 8.5 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat ChaC PF04752.7 EWM25894.1 - 2.5e-22 79.6 0.0 4.3e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 ChaC-like protein PapC_C PF13953.1 EWM25894.1 - 0.0015 18.1 0.4 0.063 12.9 0.0 3.1 3 0 0 3 3 3 1 PapC C-terminal domain DUF4213 PF13938.1 EWM25894.1 - 0.043 13.9 0.7 0.79 9.9 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4213) HNH_2 PF13391.1 EWM25894.1 - 0.12 12.2 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 HNH endonuclease AIG2_2 PF13772.1 EWM25894.1 - 0.13 12.4 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 AIG2-like family Reg_prop PF07494.6 EWM25894.1 - 0.35 11.0 3.6 2.3 8.5 0.1 3.4 3 0 0 3 3 3 0 Two component regulator propeller UQ_con PF00179.21 EWM25895.1 - 1.1e-17 63.7 0.0 1.3e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EWM25895.1 - 0.0055 16.5 0.0 0.0075 16.1 0.0 1.3 1 0 0 1 1 1 1 RWD domain Zip PF02535.17 EWM25896.1 - 1.4e-51 175.4 6.8 1.7e-51 175.0 4.7 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF4212 PF13937.1 EWM25896.1 - 0.001 19.0 0.3 0.0043 17.0 0.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4212) CreA PF05981.7 EWM25897.1 - 3.2e-34 117.2 0.1 5.2e-34 116.5 0.1 1.3 1 0 0 1 1 1 1 CreA protein DUF2358 PF10184.4 EWM25897.1 - 8e-17 61.1 0.0 1.7e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) Glyco_transf_15 PF01793.11 EWM25898.1 - 0.00066 18.7 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF4185 PF13810.1 EWM25898.1 - 0.0018 17.2 0.2 0.0085 15.0 0.0 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4185) Aldedh PF00171.17 EWM25899.1 - 1e-176 587.8 0.0 1.2e-176 587.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EWM25899.1 - 0.041 13.1 0.2 0.17 11.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) MFS_1 PF07690.11 EWM25900.1 - 3.3e-22 78.6 14.5 9e-13 47.6 3.9 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Aconitase PF00330.15 EWM25901.1 - 6.4e-75 252.4 0.0 1.1e-53 182.4 0.0 2.1 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) PrsW-protease PF13367.1 EWM25903.1 - 4.4e-14 52.1 8.9 4.4e-14 52.1 6.2 1.8 2 0 0 2 2 2 1 Protease prsW family DUF2324 PF10086.4 EWM25903.1 - 0.00016 20.9 4.1 0.0011 18.2 0.2 2.8 2 1 0 2 2 2 2 Putative membrane peptidase family (DUF2324) E1_DerP2_DerF2 PF02221.10 EWM25905.1 - 2.4e-12 47.2 0.0 2.9e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 ML domain MoaC PF01967.16 EWM25905.1 - 0.089 12.4 0.0 0.27 10.8 0.0 1.7 1 1 1 2 2 2 0 MoaC family ABC2_membrane PF01061.19 EWM25905.1 - 0.11 11.6 0.2 0.14 11.2 0.2 1.1 1 0 0 1 1 1 0 ABC-2 type transporter RRM_6 PF14259.1 EWM25906.1 - 2.9e-08 33.5 0.0 0.00012 22.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EWM25906.1 - 3.5e-08 32.9 0.0 2.1e-06 27.2 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM25906.1 - 0.0095 15.7 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peripla_BP_2 PF01497.13 EWM25907.1 - 7.2e-40 136.5 0.0 9.2e-40 136.2 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding protein Pyrophosphatase PF00719.14 EWM25908.1 - 1e-49 167.9 0.0 1.3e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Aldo_ket_red PF00248.16 EWM25910.1 - 2.1e-25 89.0 0.0 2.7e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family NicO PF03824.11 EWM25911.1 - 1e-05 25.0 0.4 1e-05 25.0 0.3 2.3 2 0 0 2 2 2 2 High-affinity nickel-transport protein DUF308 PF03729.8 EWM25911.1 - 0.013 15.5 0.6 0.013 15.5 0.4 3.5 2 1 1 3 3 3 0 Short repeat of unknown function (DUF308) HupE_UreJ_2 PF13795.1 EWM25911.1 - 0.13 11.7 4.8 0.3 10.5 0.2 2.5 2 1 0 2 2 2 0 HupE / UreJ protein Sulfate_transp PF00916.15 EWM25912.1 - 1.5e-50 171.8 8.5 7.4e-50 169.5 5.9 2.0 1 1 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EWM25912.1 - 5.1e-29 99.7 1.6 5.1e-29 99.7 1.1 2.5 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EWM25912.1 - 9.9e-14 50.7 0.0 5.5e-13 48.3 0.0 2.2 2 1 0 2 2 2 1 STAS domain STAS_2 PF13466.1 EWM25912.1 - 0.00081 19.3 0.6 0.014 15.3 0.0 2.7 2 0 0 2 2 2 1 STAS domain DnaJ PF00226.26 EWM25913.1 - 7.4e-24 83.2 0.1 1.6e-23 82.2 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain Arg_repressor_C PF02863.13 EWM25914.1 - 0.12 11.8 0.0 0.3 10.5 0.0 1.6 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain RAP1 PF07218.6 EWM25914.1 - 2.8 5.9 10.1 3 5.8 7.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.4 EWM25914.1 - 7.5 4.7 7.6 9.5 4.3 5.3 1.1 1 0 0 1 1 1 0 Transmembrane protein VKOR PF07884.9 EWM25915.1 - 8.9e-26 90.3 1.3 1.4e-25 89.7 0.9 1.3 1 0 0 1 1 1 1 Vitamin K epoxide reductase family Peptidase_M16 PF00675.15 EWM25916.1 - 3.1e-37 127.6 0.0 6.4e-36 123.3 0.0 2.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EWM25916.1 - 4.1e-19 68.9 0.1 2.1e-08 34.0 0.0 5.5 4 2 1 5 5 5 4 Peptidase M16 inactive domain CS PF04969.11 EWM25917.1 - 5.8e-17 62.0 0.0 2.1e-07 31.3 0.0 2.6 2 1 0 2 2 2 2 CS domain PHD PF00628.24 EWM25918.1 - 1.7e-26 91.6 85.2 4e-09 36.0 6.2 8.4 6 1 2 8 8 8 6 PHD-finger SET PF00856.23 EWM25918.1 - 1.7e-23 83.7 0.2 1.7e-23 83.7 0.1 3.8 3 0 0 3 3 3 1 SET domain Bromodomain PF00439.20 EWM25918.1 - 2.4e-18 65.8 0.0 4.7e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Bromodomain FYRN PF05964.9 EWM25918.1 - 7.8e-15 54.0 0.0 1.5e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus zf-HC5HC2H PF13771.1 EWM25918.1 - 1.1e-12 47.9 10.2 1.1e-12 47.9 7.1 8.2 5 2 2 7 7 7 2 PHD-like zinc-binding domain PWWP PF00855.12 EWM25918.1 - 1.7e-09 37.7 0.1 8.8e-09 35.4 0.1 2.3 1 0 0 1 1 1 1 PWWP domain zf-HC5HC2H_2 PF13832.1 EWM25918.1 - 5.1e-08 32.8 9.0 5.1e-08 32.8 6.3 7.0 5 1 1 6 6 6 2 PHD-zinc-finger like domain FYRC PF05965.9 EWM25918.1 - 0.0025 17.5 0.0 0.04 13.7 0.0 2.5 2 0 0 2 2 2 1 F/Y rich C-terminus Epimerase PF01370.16 EWM25919.1 - 1.4e-51 175.2 0.0 3e-51 174.1 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.1 EWM25919.1 - 4.5e-19 68.7 0.0 1.3e-18 67.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM25919.1 - 2.6e-15 56.6 0.0 5.3e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EWM25919.1 - 4.5e-13 48.8 0.0 1e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EWM25919.1 - 4.5e-08 33.4 0.0 9.9e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.10 EWM25919.1 - 9.3e-08 31.3 0.5 1.8e-05 23.8 0.5 3.0 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EWM25919.1 - 1.1e-07 31.0 0.0 2.1e-05 23.5 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain Methyltransf_31 PF13847.1 EWM25919.1 - 1.3e-07 31.3 0.0 2.6e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM25919.1 - 1.6e-06 28.3 0.0 3.4e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM25919.1 - 0.00059 20.3 0.0 0.002 18.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain 3Beta_HSD PF01073.14 EWM25919.1 - 0.005 15.5 0.2 0.014 14.0 0.1 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NodS PF05401.6 EWM25919.1 - 0.026 13.8 0.0 0.044 13.1 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) NAD_binding_4 PF07993.7 EWM25919.1 - 0.12 11.3 0.1 0.9 8.4 0.0 2.0 2 0 0 2 2 2 0 Male sterility protein SlyX PF04102.7 EWM25920.1 - 0.0014 18.9 1.3 0.003 17.8 0.9 1.5 1 0 0 1 1 1 1 SlyX DUF2360 PF10152.4 EWM25920.1 - 0.028 14.7 0.6 0.051 13.8 0.4 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Med9 PF07544.8 EWM25920.1 - 0.14 11.9 0.4 0.21 11.3 0.3 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 AKAP7_RIRII_bdg PF10470.4 EWM25920.1 - 0.31 10.8 2.2 0.37 10.6 0.2 2.1 2 0 0 2 2 2 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein F5_F8_type_C PF00754.20 EWM25921.1 - 0.00074 19.3 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain APC10 PF03256.11 EWM25921.1 - 0.053 13.1 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) Metaviral_G PF09595.5 EWM25921.1 - 0.059 12.9 0.9 0.087 12.4 0.7 1.3 1 0 0 1 1 1 0 Metaviral_G glycoprotein PC-Esterase PF13839.1 EWM25922.1 - 1.2e-08 35.0 0.1 2.9e-05 24.0 0.0 2.7 3 0 0 3 3 3 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Fer4_16 PF13484.1 EWM25923.1 - 1.1e-16 61.2 6.1 2.3e-16 60.2 4.2 1.5 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain DUF1730 PF08331.5 EWM25923.1 - 1.5e-14 53.3 0.0 1.4e-12 47.0 0.0 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF1730) Fer4_10 PF13237.1 EWM25923.1 - 2.1e-08 33.8 7.3 4.6e-08 32.7 5.0 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 EWM25923.1 - 6.5e-08 32.8 4.6 1.7e-07 31.5 3.3 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EWM25923.1 - 7.4e-05 23.0 2.0 0.013 15.9 0.1 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EWM25923.1 - 7.6e-05 22.9 7.6 0.00047 20.3 5.5 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.22 EWM25923.1 - 0.00051 19.5 13.2 0.0038 16.7 2.1 2.7 3 0 0 3 3 3 2 4Fe-4S binding domain DUF2411 PF10304.4 EWM25923.1 - 0.005 16.3 0.1 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) Fer4_2 PF12797.2 EWM25923.1 - 0.0074 16.1 13.7 0.21 11.5 2.8 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_4 PF12800.2 EWM25923.1 - 0.013 15.7 8.7 0.47 10.9 2.6 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.2 EWM25923.1 - 0.015 15.7 12.1 0.49 11.0 0.5 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_21 PF14697.1 EWM25923.1 - 0.021 14.6 10.5 0.16 11.8 7.2 2.1 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_6 PF12837.2 EWM25923.1 - 0.023 14.5 4.0 0.023 14.5 2.8 2.5 2 1 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.1 EWM25923.1 - 0.05 13.6 8.7 0.26 11.3 6.0 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_11 PF13247.1 EWM25923.1 - 0.13 12.1 2.5 0.48 10.3 1.7 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_17 PF13534.1 EWM25923.1 - 0.3 11.4 9.2 13 6.2 7.3 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain Glyco_hydro_43 PF04616.9 EWM25924.1 - 9.5e-13 47.8 0.2 1.5e-12 47.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 PC-Esterase PF13839.1 EWM25925.1 - 6.1e-10 39.3 0.0 5.8e-05 23.0 0.0 3.2 3 0 0 3 3 3 3 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Pkinase PF00069.20 EWM25926.1 - 1e-63 214.9 0.0 1.6e-63 214.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM25926.1 - 6.6e-48 163.0 0.0 1e-47 162.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EWM25926.1 - 0.028 13.4 0.0 0.049 12.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like NUDIX PF00293.23 EWM25927.1 - 3.6e-16 59.0 0.2 5e-16 58.5 0.2 1.2 1 0 0 1 1 1 1 NUDIX domain Peptidase_S9 PF00326.16 EWM25928.1 - 2.5e-09 36.6 0.1 1.9e-07 30.5 0.1 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EWM25928.1 - 1.1e-08 34.8 0.0 1.5e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EWM25928.1 - 1.5e-06 28.0 0.0 1.7e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EWM25928.1 - 0.0034 17.2 0.0 0.015 15.1 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EWM25928.1 - 0.017 14.5 0.1 0.026 13.9 0.1 1.3 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.15 EWM25928.1 - 0.039 13.4 0.0 3.7 7.0 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 EWM25928.1 - 0.047 13.5 0.0 0.091 12.6 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein AcetylCoA_hyd_C PF13336.1 EWM25929.1 - 8.2e-58 194.4 0.0 1.3e-57 193.7 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.10 EWM25929.1 - 3.1e-22 79.3 0.0 5.8e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain PsbX PF06596.6 EWM25929.1 - 0.021 14.4 0.2 0.64 9.7 0.0 2.4 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) Acetyltransf_1 PF00583.19 EWM25931.1 - 4e-13 49.1 0.0 9.2e-13 48.0 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EWM25931.1 - 3.4e-07 30.3 0.0 6.8e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EWM25931.1 - 5.1e-06 26.5 0.1 1.3e-05 25.3 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EWM25931.1 - 0.00015 21.9 0.0 0.00032 20.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EWM25931.1 - 0.00017 21.4 0.1 0.00051 19.9 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EWM25931.1 - 0.00032 20.4 0.0 0.00083 19.0 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EWM25931.1 - 0.00042 20.1 0.0 0.00079 19.2 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 EWM25931.1 - 0.00049 20.0 0.0 0.00086 19.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EWM25931.1 - 0.0038 17.1 0.0 0.008 16.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2865 PF11064.3 EWM25932.1 - 0.32 10.8 5.6 0.22 11.4 1.9 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2865) PPDK_N PF01326.14 EWM25933.1 - 1.4e-46 159.0 0.0 1.9e-46 158.6 0.0 1.1 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain VGCC_beta4Aa_N PF12052.3 EWM25933.1 - 0.48 10.3 3.2 0.46 10.3 0.4 2.1 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal Acyl_transf_3 PF01757.17 EWM25934.1 - 3.1e-16 59.1 37.3 4.8e-16 58.5 25.9 1.3 1 0 0 1 1 1 1 Acyltransferase family Rcd1 PF04078.8 EWM25934.1 - 0.021 13.6 0.0 0.034 12.9 0.0 1.2 1 0 0 1 1 1 0 Cell differentiation family, Rcd1-like Prefoldin_2 PF01920.15 EWM25937.1 - 1.2e-14 53.9 9.9 1.5e-14 53.6 6.9 1.2 1 0 0 1 1 1 1 Prefoldin subunit DND1_DSRM PF14709.1 EWM25937.1 - 0.071 13.4 0.3 11 6.3 0.3 2.3 2 0 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 DUF1664 PF07889.7 EWM25937.1 - 0.075 12.8 5.7 0.036 13.8 1.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.6 EWM25937.1 - 0.082 12.7 6.3 0.14 12.0 1.1 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Phage_GP20 PF06810.6 EWM25937.1 - 0.12 11.8 10.0 0.023 14.1 3.4 1.9 2 0 0 2 2 2 0 Phage minor structural protein GP20 Atg14 PF10186.4 EWM25937.1 - 0.17 10.7 6.0 0.29 10.0 4.2 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 OmpH PF03938.9 EWM25937.1 - 0.2 11.5 17.7 0.4 10.6 12.3 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1492 PF07374.6 EWM25937.1 - 0.38 10.8 2.9 0.62 10.1 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1492) Prefoldin PF02996.12 EWM25937.1 - 0.57 9.8 9.0 3.3 7.3 6.2 2.3 1 1 0 1 1 1 0 Prefoldin subunit DMPK_coil PF08826.5 EWM25937.1 - 0.6 10.0 9.2 0.044 13.6 2.4 2.0 2 1 0 2 2 2 0 DMPK coiled coil domain like Spc24 PF08286.6 EWM25937.1 - 0.63 9.7 10.4 1.3 8.6 3.4 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 AATF-Che1 PF13339.1 EWM25937.1 - 0.68 10.0 5.4 0.19 11.9 1.4 1.7 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor Spc7 PF08317.6 EWM25937.1 - 0.89 8.1 6.9 1.2 7.7 4.8 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4615 PF15393.1 EWM25937.1 - 1.5 9.0 5.1 3.9 7.7 2.0 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4615) Syntaxin-6_N PF09177.6 EWM25937.1 - 1.5 9.2 4.2 16 6.0 2.9 2.2 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Fib_alpha PF08702.5 EWM25937.1 - 1.7 8.7 5.2 0.88 9.6 1.0 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1342 PF07072.6 EWM25937.1 - 2.1 7.9 5.9 3.4 7.2 3.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1342) M PF02370.11 EWM25937.1 - 4.5 7.9 6.8 5.8 7.6 0.0 3.8 3 0 0 3 3 3 0 M protein repeat Mod_r PF07200.8 EWM25937.1 - 4.9 7.0 9.4 0.88 9.4 2.3 2.0 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Tup_N PF08581.5 EWM25937.1 - 8.2 6.7 7.9 7.5 6.8 1.0 2.3 2 0 0 2 2 2 0 Tup N-terminal PEP-utilizers_C PF02896.13 EWM25939.1 - 4.4e-88 294.9 0.0 5.2e-88 294.7 0.0 1.0 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.18 EWM25939.1 - 5.4e-10 38.7 0.2 1.8e-09 36.9 0.1 2.0 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain PEPCK_ATP PF01293.15 EWM25940.1 - 0.022 13.2 0.0 0.031 12.8 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase Imm28 PF15574.1 EWM25941.1 - 0.2 11.1 0.0 0.41 10.2 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 28 TP_methylase PF00590.15 EWM25943.1 - 1.3e-43 149.1 0.6 2e-43 148.5 0.4 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases SNARE_assoc PF09335.6 EWM25944.1 - 0.097 12.8 3.9 0.12 12.5 1.6 2.0 2 1 0 2 2 2 0 SNARE associated Golgi protein NAD_binding_2 PF03446.10 EWM25945.1 - 9.5e-46 155.6 0.7 1.3e-45 155.1 0.5 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EWM25945.1 - 4.6e-33 113.8 2.5 5.3e-33 113.6 1.0 1.6 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EWM25945.1 - 6.5e-07 29.6 0.0 1.2e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EWM25945.1 - 0.0001 22.4 0.1 0.0003 20.9 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 EWM25945.1 - 0.00023 20.3 0.0 0.00038 19.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 EWM25945.1 - 0.0041 16.5 0.5 0.011 15.2 0.0 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EWM25945.1 - 0.038 13.6 0.1 0.064 12.9 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Abhydrolase_6 PF12697.2 EWM25946.1 - 4e-15 56.3 4.5 4e-15 56.3 3.1 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM25946.1 - 5.8e-09 35.8 0.2 7.8e-09 35.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EWM25946.1 - 0.00029 20.4 0.1 0.00046 19.8 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold UPF0227 PF05728.7 EWM25946.1 - 0.056 13.1 0.0 0.12 12.0 0.0 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) Esterase PF00756.15 EWM25946.1 - 0.089 12.2 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.3 EWM25946.1 - 0.12 12.2 0.0 0.33 10.8 0.0 1.8 2 0 0 2 2 2 0 Putative lysophospholipase Pkinase PF00069.20 EWM25947.1 - 1.5e-42 145.5 0.0 1.8e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM25947.1 - 1.5e-24 86.4 0.0 2e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EWM25947.1 - 5.2e-06 25.6 0.0 7.2e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EWM25947.1 - 1.6e-05 24.7 0.2 0.14 11.8 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.17 EWM25947.1 - 0.051 12.9 0.0 0.071 12.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.4 EWM25947.1 - 0.15 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL ETC_C1_NDUFA5 PF04716.9 EWM25948.1 - 2.4e-10 39.7 0.7 3.6e-10 39.2 0.5 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region ThiF PF00899.16 EWM25950.1 - 4.7e-16 58.8 0.0 5.8e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 ThiF family Coprogen_oxidas PF01218.13 EWM25951.1 - 4.7e-127 422.6 0.3 5.6e-127 422.3 0.2 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase PPR_3 PF13812.1 EWM25952.1 - 0.011 15.9 1.9 9.6 6.7 0.2 3.5 3 0 0 3 3 3 0 Pentatricopeptide repeat domain BSP_II PF05432.6 EWM25952.1 - 7.8 5.6 22.4 0.35 10.1 6.7 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) CRAL_TRIO PF00650.15 EWM25953.1 - 3.6e-07 29.8 0.0 4.8e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EWM25953.1 - 0.01 15.7 0.0 0.018 14.9 0.0 1.4 1 1 0 1 1 1 0 Divergent CRAL/TRIO domain Proteasome PF00227.21 EWM25954.1 - 4.9e-49 166.2 0.1 6.3e-49 165.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EWM25954.1 - 1.9e-13 49.4 0.1 3.9e-13 48.4 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Furin-like PF00757.15 EWM25956.1 - 0.094 12.3 0.9 0.099 12.2 0.7 1.0 1 0 0 1 1 1 0 Furin-like cysteine rich region HSF_DNA-bind PF00447.12 EWM25958.1 - 8.7e-25 86.9 0.3 1.5e-24 86.0 0.2 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding MIP-T3 PF10243.4 EWM25958.1 - 0.95 7.8 5.0 1.4 7.3 3.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Epimerase_Csub PF13950.1 EWM25959.1 - 0.002 18.0 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit TAA-Trp-ring PF15401.1 EWM25959.1 - 0.067 13.4 0.0 0.09 13.0 0.0 1.3 1 0 0 1 1 1 0 Tryptophan-ring motif of head of Trimeric autotransporter adhesin EamA PF00892.15 EWM25961.1 - 4.1e-29 101.1 24.4 1.1e-14 54.5 4.3 2.1 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EWM25961.1 - 1.1e-05 25.5 23.7 0.0006 19.9 3.6 3.0 2 2 0 2 2 2 2 Multidrug resistance efflux transporter TPT PF03151.11 EWM25961.1 - 0.00013 21.6 3.3 0.00013 21.6 2.3 2.6 2 2 0 2 2 2 1 Triose-phosphate Transporter family Epimerase PF01370.16 EWM25963.1 - 1.2e-54 185.2 0.0 1.6e-54 184.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EWM25963.1 - 2.5e-08 33.1 0.0 4.2e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EWM25963.1 - 1.2e-05 24.3 0.0 1.7e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EWM25963.1 - 0.00081 19.3 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EWM25963.1 - 0.039 13.6 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 KR domain NmrA PF05368.8 EWM25963.1 - 0.044 13.0 0.0 0.062 12.5 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family LRR_6 PF13516.1 EWM25964.1 - 1.8e-17 61.3 9.2 0.0052 16.7 0.0 6.7 7 0 0 7 7 7 5 Leucine Rich repeat LRR_4 PF12799.2 EWM25964.1 - 3.9e-07 29.5 0.9 0.66 9.6 0.0 5.1 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EWM25964.1 - 6.3e-07 28.5 2.5 1.8 9.0 0.0 5.4 6 0 0 6 6 6 1 Leucine rich repeat LRR_8 PF13855.1 EWM25964.1 - 0.00014 21.5 5.1 0.75 9.6 1.6 5.0 4 1 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 EWM25964.1 - 0.0019 17.9 7.7 11 6.5 0.0 5.5 7 0 0 7 7 7 2 Leucine Rich Repeat DUF3464 PF11947.3 EWM25966.1 - 2.1e-29 101.9 0.0 3e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3464) adh_short PF00106.20 EWM25967.1 - 1.4e-26 93.3 0.2 1.8e-26 93.0 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EWM25967.1 - 5.2e-12 45.7 0.6 1.1e-11 44.7 0.4 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EWM25967.1 - 3.5e-07 30.2 0.0 5.2e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EWM25967.1 - 5e-06 25.8 0.0 3.5e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EWM25967.1 - 0.00016 21.7 0.8 0.00059 19.8 0.5 2.0 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EWM25967.1 - 0.085 12.6 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EWM25967.1 - 0.14 11.5 0.3 0.91 8.9 0.2 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ArsR PF09824.4 EWM25967.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 ArsR transcriptional regulator HRDC PF00570.18 EWM25968.1 - 4.3e-10 39.1 0.4 5.9e-08 32.3 0.0 2.5 1 1 2 3 3 3 2 HRDC domain DUF2310 PF10071.4 EWM25968.1 - 0.15 11.0 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) DEAD PF00270.24 EWM25969.1 - 5.1e-17 61.8 0.0 6.7e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD PF00270.24 EWM25970.1 - 1.1e-44 151.8 0.0 2.4e-44 150.7 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EWM25970.1 - 3.2e-21 74.9 0.1 5.8e-21 74.1 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EWM25970.1 - 0.0098 15.7 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Synaptobrevin PF00957.16 EWM25971.1 - 4.8e-28 96.5 0.1 7.7e-28 95.9 0.1 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EWM25971.1 - 1.7e-20 72.3 0.0 2.7e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain RNA_pol_Rbc25 PF08292.7 EWM25972.1 - 0.099 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 RF-1 PF00472.15 EWM25973.1 - 4.9e-33 113.3 0.1 8.9e-33 112.4 0.1 1.4 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 EWM25973.1 - 2.7e-26 91.5 0.3 2.7e-26 91.5 0.2 1.8 2 0 0 2 2 2 1 PCRF domain Nop14 PF04147.7 EWM25974.1 - 0.052 11.4 0.3 0.071 11.0 0.2 1.1 1 0 0 1 1 1 0 Nop14-like family VID27 PF08553.5 EWM25974.1 - 2.9 6.0 5.0 4 5.5 3.5 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Sulfate_transp PF00916.15 EWM25975.1 - 1.6e-25 89.6 2.2 4e-25 88.3 0.2 2.1 1 1 1 2 2 2 1 Sulfate transporter family STAS PF01740.16 EWM25975.1 - 1.6e-13 50.0 0.0 2.9e-13 49.2 0.0 1.4 1 1 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EWM25975.1 - 3.3e-06 27.0 0.6 2.7e-05 24.1 0.1 2.4 2 0 0 2 2 2 1 STAS domain NfeD PF01957.13 EWM25975.1 - 0.94 9.6 5.2 0.68 10.0 2.0 2.0 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding PX PF00787.19 EWM25978.1 - 0.011 15.4 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 PX domain Prenyltrans_1 PF13243.1 EWM25979.1 - 1.9e-14 53.5 0.5 3.9e-10 39.7 0.1 2.0 1 1 1 2 2 2 2 Prenyltransferase-like Prenyltrans PF00432.16 EWM25979.1 - 7.7e-12 44.5 5.2 5.2e-09 35.5 1.8 3.2 2 1 0 2 2 2 2 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EWM25979.1 - 1.2e-09 38.6 0.2 8e-09 35.9 0.1 1.8 1 1 0 1 1 1 1 Prenyltransferase-like Pec_lyase PF09492.5 EWM25979.1 - 4.4e-06 26.0 0.1 0.0082 15.3 0.0 2.0 2 0 0 2 2 2 2 Pectic acid lyase A2M_comp PF07678.9 EWM25979.1 - 0.025 13.8 0.0 5.6 6.1 0.0 2.1 1 1 1 2 2 2 0 A-macroglobulin complement component SPX PF03105.14 EWM25982.1 - 0.00021 21.1 0.1 0.00033 20.5 0.1 1.3 1 0 0 1 1 1 1 SPX domain DnaJ PF00226.26 EWM25983.1 - 2.2e-28 97.7 2.0 3.6e-28 97.0 1.4 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EWM25983.1 - 8.3e-07 28.8 0.5 0.00014 21.6 0.0 2.7 2 1 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 EWM25984.1 - 2.1e-14 53.0 0.7 3.7e-14 52.2 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EWM25984.1 - 9.6e-07 28.6 0.5 0.00015 21.5 0.0 2.7 2 1 0 2 2 2 2 DnaJ C terminal domain E1-E2_ATPase PF00122.15 EWM25985.1 - 5.1e-52 176.2 3.4 5.1e-52 176.2 2.4 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EWM25985.1 - 4.9e-25 89.2 0.1 1.2e-24 87.9 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EWM25985.1 - 9.7e-13 48.7 0.0 2.3e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EWM25985.1 - 1.7e-12 46.5 0.0 1.7e-12 46.5 0.0 2.4 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EWM25985.1 - 6.7e-05 22.5 0.4 0.00052 19.6 0.1 2.1 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase FumaraseC_C PF10415.4 EWM25986.1 - 0.11 12.5 1.2 0.2 11.7 0.0 2.0 2 0 0 2 2 2 0 Fumarase C C-terminus PRA-PH PF01503.12 EWM25986.1 - 0.12 12.7 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase COX17 PF05051.8 EWM25988.1 - 1.5e-20 72.9 7.7 2.9e-20 72.0 5.3 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) E1-E2_ATPase PF00122.15 EWM25989.1 - 2.8e-51 173.7 2.5 2.8e-51 173.7 1.7 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EWM25989.1 - 6.1e-25 88.8 0.1 1.6e-24 87.5 0.1 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EWM25989.1 - 6.6e-14 51.1 0.9 1.7e-13 49.8 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EWM25989.1 - 9.3e-13 48.7 0.0 2.7e-12 47.2 0.0 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EWM25989.1 - 1.6e-05 24.6 0.0 0.00022 20.9 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EWM25990.1 - 2.4e-51 173.9 2.5 2.4e-51 173.9 1.7 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EWM25990.1 - 5.4e-25 89.0 0.1 1.3e-24 87.7 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EWM25990.1 - 5.7e-14 51.3 0.9 1.5e-13 50.0 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EWM25990.1 - 7.8e-13 49.0 0.0 2.3e-12 47.4 0.0 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EWM25990.1 - 1.4e-05 24.8 0.0 0.00019 21.0 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase IL11 PF07400.6 EWM25991.1 - 0.0085 15.6 0.2 0.0085 15.6 0.1 2.1 2 1 0 2 2 2 1 Interleukin 11 Baculo_PEP_C PF04513.7 EWM25991.1 - 0.069 12.9 0.2 0.26 11.0 0.1 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CorA PF01544.13 EWM25991.1 - 5.7 5.8 13.9 0.91 8.4 1.8 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein IL11 PF07400.6 EWM25992.1 - 0.012 15.1 0.2 0.012 15.1 0.2 2.1 2 1 0 2 2 2 0 Interleukin 11 CorA PF01544.13 EWM25992.1 - 0.85 8.5 13.1 0.14 11.1 1.4 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein AIRS_C PF02769.17 EWM25994.1 - 2.1e-14 53.7 0.9 7.4e-14 52.0 0.6 1.8 1 1 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EWM25994.1 - 4.6e-14 52.4 0.0 1.1e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Pyr_redox_2 PF07992.9 EWM25994.1 - 0.00054 19.9 0.0 0.00088 19.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_9 PF00759.14 EWM25995.1 - 4.2e-27 95.1 0.0 5.3e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 TPR_19 PF14559.1 EWM25996.1 - 3.5e-06 27.2 0.8 3.5e-06 27.2 0.5 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EWM25996.1 - 0.0012 18.7 4.0 0.051 13.5 2.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EWM25996.1 - 0.0019 18.6 0.6 0.0019 18.6 0.4 3.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EWM25996.1 - 0.0035 17.9 2.7 0.0035 17.9 1.9 2.3 2 1 1 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EWM25996.1 - 0.034 14.2 0.2 0.065 13.3 0.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Foie-gras_1 PF11817.3 EWM25996.1 - 0.11 11.9 0.5 0.13 11.6 0.3 1.1 1 0 0 1 1 1 0 Foie gras liver health family 1 TPR_2 PF07719.12 EWM25996.1 - 0.13 12.2 6.7 2.1 8.4 2.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EWM25996.1 - 0.15 11.6 1.4 0.32 10.6 0.4 1.8 1 1 1 2 2 2 0 TPR repeat TPR_4 PF07721.9 EWM25996.1 - 0.65 10.6 9.0 0.25 11.8 1.5 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat MoCF_biosynth PF00994.19 EWM25998.1 - 1.1e-19 70.2 0.1 1.2e-19 70.0 0.1 1.0 1 0 0 1 1 1 1 Probable molybdopterin binding domain TPR_12 PF13424.1 EWM25999.1 - 0.03 14.2 0.1 0.6 10.0 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat RRM_1 PF00076.17 EWM26001.1 - 3.7e-19 68.1 0.0 9.2e-19 66.8 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM26001.1 - 1.3e-12 47.4 0.0 2.2e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM26001.1 - 1.5e-09 37.5 0.0 2.3e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EWM26001.1 - 0.044 13.5 0.0 0.11 12.2 0.0 1.7 1 1 1 2 2 2 0 Limkain b1 MoeA_N PF03453.12 EWM26002.1 - 2.2e-29 101.9 0.1 2.7e-29 101.6 0.1 1.1 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) SET PF00856.23 EWM26005.1 - 4.3e-11 43.3 0.0 4.8e-09 36.7 0.0 2.4 1 1 0 1 1 1 1 SET domain zf-met PF12874.2 EWM26007.1 - 4.9e-10 39.2 6.7 1.4e-08 34.6 0.7 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EWM26007.1 - 3.4e-08 33.4 0.9 3.4e-08 33.4 0.7 2.6 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EWM26007.1 - 1.2e-06 28.4 5.0 0.00076 19.5 0.8 2.1 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EWM26007.1 - 6.4e-05 23.0 5.3 0.027 14.8 0.3 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger AKAP95 PF04988.7 EWM26007.1 - 0.00039 20.2 5.5 0.15 11.8 0.4 2.1 2 0 0 2 2 2 2 A-kinase anchoring protein 95 (AKAP95) zf-DBF PF07535.7 EWM26007.1 - 0.00042 19.9 4.0 0.012 15.2 0.1 2.2 1 1 1 2 2 2 2 DBF zinc finger DUF4187 PF13821.1 EWM26007.1 - 0.0047 16.4 2.4 0.25 10.9 0.3 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4187) zf-BED PF02892.10 EWM26007.1 - 0.044 13.5 0.7 1.4 8.7 0.1 2.3 2 0 0 2 2 2 0 BED zinc finger zf-C2H2 PF00096.21 EWM26007.1 - 0.045 14.1 9.3 0.16 12.4 1.4 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF3505 PF12013.3 EWM26007.1 - 0.082 13.1 3.9 0.14 12.4 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3505) zf-H2C2_2 PF13465.1 EWM26007.1 - 3.3 8.1 8.0 12 6.4 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger double domain DUF1649 PF07855.7 EWM26010.1 - 1.2e-17 64.0 0.0 4.1e-14 52.5 0.0 2.3 2 1 0 2 2 2 2 Protein of unknown function (DUF1649) M-inducer_phosp PF06617.8 EWM26010.1 - 0.097 11.7 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 M-phase inducer phosphatase DUF1649 PF07855.7 EWM26011.1 - 7.9e-18 64.6 0.0 3e-14 52.9 0.0 2.3 2 1 0 2 2 2 2 Protein of unknown function (DUF1649) M-inducer_phosp PF06617.8 EWM26011.1 - 0.08 11.9 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 M-phase inducer phosphatase FA_hydroxylase PF04116.8 EWM26012.1 - 7.3e-09 36.0 17.9 7.3e-09 36.0 12.4 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily IncA PF04156.9 EWM26012.1 - 6.4 6.3 7.7 11 5.6 5.3 1.3 1 0 0 1 1 1 0 IncA protein RAP PF08373.5 EWM26013.1 - 0.0013 18.4 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 RAP domain FAST_1 PF06743.10 EWM26013.1 - 0.085 12.5 0.4 6.4 6.5 0.0 3.6 4 0 0 4 4 4 0 FAST kinase-like protein, subdomain 1 Zip PF02535.17 EWM26014.1 - 0.21 10.5 5.5 0.4 9.6 3.0 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter PGM_PMM_IV PF00408.15 EWM26015.1 - 9.1e-10 38.4 0.0 2.5e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 EWM26015.1 - 3.9e-07 30.0 0.0 1.3e-06 28.4 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_I PF02878.11 EWM26015.1 - 1.3e-05 24.7 0.0 3.8e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EWM26015.1 - 7.8e-05 22.9 0.1 0.0018 18.5 0.0 2.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Abhydrolase_3 PF07859.8 EWM26016.1 - 1e-13 51.3 0.0 1.2e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Fer2 PF00111.22 EWM26017.1 - 3.6e-09 36.2 0.1 6.2e-09 35.4 0.1 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.1 EWM26017.1 - 0.0096 15.7 0.1 0.023 14.4 0.1 1.6 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain PSI PF01437.20 EWM26017.1 - 0.94 9.6 6.0 3 8.0 0.4 2.2 2 0 0 2 2 2 0 Plexin repeat PCI PF01399.22 EWM26019.1 - 1.4e-19 70.3 0.3 4.5e-19 68.6 0.2 1.9 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 EWM26019.1 - 5.6e-09 35.9 2.2 5.8e-09 35.8 0.5 1.8 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 TPR_12 PF13424.1 EWM26019.1 - 4.9e-06 26.3 1.7 0.0096 15.8 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EWM26019.1 - 0.00018 21.2 3.4 4.3 7.4 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat HTH_Mga PF08280.6 EWM26019.1 - 0.028 14.1 0.1 0.056 13.2 0.1 1.4 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain TPR_7 PF13176.1 EWM26019.1 - 0.05 13.4 0.4 6.9 6.7 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EWM26019.1 - 0.05 13.2 3.6 23 4.7 0.0 4.1 4 0 0 4 4 4 0 TPR repeat TPR_8 PF13181.1 EWM26019.1 - 0.051 13.3 0.8 1.1 9.1 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DDRGK PF09756.4 EWM26019.1 - 0.095 12.0 0.2 0.26 10.6 0.0 1.8 2 0 0 2 2 2 0 DDRGK domain Sigma70_r4 PF04545.11 EWM26019.1 - 0.11 11.7 1.4 0.36 10.1 1.0 1.9 1 0 0 1 1 1 0 Sigma-70, region 4 TPR_6 PF13174.1 EWM26019.1 - 0.15 12.6 2.2 18 6.0 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat SAC3_GANP PF03399.11 EWM26019.1 - 0.2 11.1 3.5 1.6 8.2 2.4 2.1 1 1 0 1 1 1 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family TPR_14 PF13428.1 EWM26019.1 - 0.27 11.9 3.5 37 5.3 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EWM26019.1 - 2.6 8.8 6.8 41 5.0 0.0 3.9 5 0 0 5 5 3 0 Tetratricopeptide repeat Abhydrolase_3 PF07859.8 EWM26021.1 - 5.1e-15 55.6 0.7 1.2e-14 54.4 0.5 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EWM26021.1 - 3.5e-06 25.9 0.0 5.5e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Redoxin PF08534.5 EWM26023.1 - 1e-30 106.1 0.0 1.2e-30 106.0 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EWM26023.1 - 1.2e-13 50.8 0.0 1.4e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF1953 PF09196.5 EWM26023.1 - 0.084 12.5 0.6 0.26 10.9 0.0 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1953) DUF3253 PF11625.3 EWM26025.1 - 5.1e-26 90.3 0.2 7.1e-26 89.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3253) Dmrt1 PF12374.3 EWM26025.1 - 3.9 7.9 11.4 4.1 7.8 0.1 2.3 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 Cupin_8 PF13621.1 EWM26030.1 - 0.0047 16.4 0.0 0.0049 16.3 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain PSI PF01437.20 EWM26031.1 - 0.0023 18.0 10.1 0.0047 17.0 7.0 1.6 1 0 0 1 1 1 1 Plexin repeat Opy2 PF09463.5 EWM26031.1 - 6.6 6.9 13.7 1.7 8.7 1.6 2.3 2 0 0 2 2 2 0 Opy2 protein HECT PF00632.20 EWM26034.1 - 4e-11 42.6 0.0 4.9e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Evr1_Alr PF04777.8 EWM26035.1 - 2e-21 75.7 1.6 7.6e-11 41.7 0.1 2.9 2 2 0 2 2 2 2 Erv1 / Alr family zf-H2C2_2 PF13465.1 EWM26035.1 - 0.023 14.9 1.5 9.6 6.7 0.1 2.9 2 0 0 2 2 2 0 Zinc-finger double domain Lar_restr_allev PF14354.1 EWM26035.1 - 0.032 14.5 0.3 0.032 14.5 0.2 2.9 2 1 0 2 2 2 0 Restriction alleviation protein Lar zf-C2HC_2 PF13913.1 EWM26035.1 - 0.056 13.1 1.5 9.8 5.9 0.2 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type UPF0547 PF10571.4 EWM26035.1 - 1.6 8.5 13.7 0.14 11.8 1.9 3.5 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 HECT PF00632.20 EWM26036.1 - 1.3e-30 106.7 0.0 1.4e-30 106.5 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) PRP8_domainIV PF12134.3 EWM26039.1 - 5.3e-50 169.9 0.0 6.5e-50 169.6 0.0 1.0 1 0 0 1 1 1 1 PRP8 domain IV core Glyco_hydro_16 PF00722.16 EWM26039.1 - 0.13 11.5 0.2 0.2 10.9 0.2 1.4 1 1 0 1 1 1 0 Glycosyl hydrolases family 16 RRM_4 PF10598.4 EWM26040.1 - 9e-39 131.2 0.9 1e-38 131.0 0.6 1.0 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCN PF08083.6 EWM26041.1 - 3.8e-21 75.0 0.0 4.5e-21 74.8 0.0 1.0 1 0 0 1 1 1 1 PROCN (NUC071) domain PROCN PF08083.6 EWM26042.1 - 7e-98 327.7 4.9 8.4e-98 327.5 3.4 1.0 1 0 0 1 1 1 1 PROCN (NUC071) domain Ribosomal_L23eN PF03939.8 EWM26043.1 - 1.2e-13 50.8 9.9 1.9e-13 50.2 6.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EWM26043.1 - 4e-08 33.0 0.2 4e-08 33.0 0.2 1.9 1 1 1 2 2 2 1 Ribosomal protein L23 IgaA PF07095.6 EWM26048.1 - 0.1 10.3 0.1 0.1 10.3 0.1 1.0 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA TrkA_C PF02080.16 EWM26055.1 - 0.14 11.7 0.1 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 TrkA-C domain FA_desaturase PF00487.19 EWM26057.1 - 0.048 13.0 12.9 0.085 12.2 9.0 1.5 1 1 0 1 1 1 0 Fatty acid desaturase YwiC PF14256.1 EWM26058.1 - 0.34 11.0 6.8 3 7.9 0.3 2.1 1 1 1 2 2 2 0 YwiC-like protein CBM_14 PF01607.19 EWM26062.1 - 0.57 10.1 6.0 0.36 10.7 0.5 2.6 2 1 0 2 2 2 0 Chitin binding Peritrophin-A domain Ald_Xan_dh_C2 PF02738.13 EWM26067.1 - 5.1e-14 51.5 0.1 8.3e-14 50.7 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase His_Phos_1 PF00300.17 EWM26069.1 - 7.8e-18 65.0 0.0 1.1e-17 64.5 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) D-aminoacyl_C PF07908.7 EWM26069.1 - 1.9 7.8 5.3 21 4.4 0.1 3.3 4 0 0 4 4 4 0 D-aminoacylase, C-terminal region Gate PF07670.9 EWM26071.1 - 3.4 7.6 6.9 5.8 6.8 2.3 3.0 2 1 0 2 2 2 0 Nucleoside recognition KASH PF10541.4 EWM26072.1 - 0.098 12.5 0.7 0.23 11.3 0.1 1.9 1 1 1 2 2 2 0 Nuclear envelope localisation domain Gate PF07670.9 EWM26072.1 - 1.8 8.5 6.9 3.9 7.4 2.3 3.0 2 1 0 2 2 2 0 Nucleoside recognition Mnd1 PF03962.10 EWM26073.1 - 5.3e-49 166.4 0.3 6.1e-49 166.2 0.2 1.0 1 0 0 1 1 1 1 Mnd1 family CCDC155 PF14662.1 EWM26073.1 - 0.0049 16.4 2.3 0.0078 15.8 1.6 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 Pkip-1 PF06878.6 EWM26073.1 - 0.018 14.9 0.8 0.028 14.3 0.6 1.3 1 0 0 1 1 1 0 Pkip-1 protein ATG16 PF08614.6 EWM26073.1 - 0.021 14.6 2.0 0.021 14.6 1.4 1.8 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) End3 PF12761.2 EWM26073.1 - 0.033 13.8 1.1 0.039 13.5 0.7 1.2 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 TrmB PF01978.14 EWM26073.1 - 0.061 13.0 0.0 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Spc7 PF08317.6 EWM26073.1 - 0.074 11.6 1.9 0.11 11.1 1.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Spc24 PF08286.6 EWM26073.1 - 0.13 11.9 4.1 0.83 9.3 1.7 2.5 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 IncA PF04156.9 EWM26073.1 - 0.16 11.5 2.7 0.23 11.0 1.9 1.2 1 0 0 1 1 1 0 IncA protein DUF2968 PF11180.3 EWM26073.1 - 0.28 10.5 7.5 0.58 9.5 4.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) ADIP PF11559.3 EWM26073.1 - 0.42 10.5 5.0 1.5 8.6 3.4 1.9 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF724 PF05266.9 EWM26073.1 - 1.6 8.3 7.3 0.58 9.7 2.6 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF724) Ribosomal_L12 PF00542.14 EWM26076.1 - 4.3e-26 90.7 11.3 7.7e-26 89.8 7.9 1.4 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain TFIIS_M PF07500.9 EWM26077.1 - 4.2e-08 33.2 0.1 7.3e-08 32.4 0.1 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain ABC_tran PF00005.22 EWM26078.1 - 2.9e-52 176.6 0.0 4.1e-25 88.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EWM26078.1 - 1.8e-20 74.1 1.0 1.8e-07 31.4 0.0 4.1 3 1 0 4 4 4 4 AAA domain ABC_tran_2 PF12848.2 EWM26078.1 - 3.4e-12 46.0 7.9 2.5e-09 36.8 0.4 2.7 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.14 EWM26078.1 - 2.2e-10 40.1 3.2 0.0061 15.8 0.1 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EWM26078.1 - 7.4e-06 26.0 3.7 0.045 13.7 0.1 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 EWM26078.1 - 9.7e-06 25.0 0.9 0.017 14.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 EWM26078.1 - 1.4e-05 25.5 0.1 0.18 12.2 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 EWM26078.1 - 2.1e-05 23.7 0.4 0.0041 16.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EWM26078.1 - 2.6e-05 24.1 0.1 0.017 15.0 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.1 EWM26078.1 - 8.8e-05 21.7 0.0 3.6 6.5 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_23 PF13476.1 EWM26078.1 - 0.00014 22.2 6.4 0.0063 16.8 0.1 2.8 3 0 0 3 3 2 2 AAA domain ArgK PF03308.11 EWM26078.1 - 0.00026 19.8 0.3 0.07 11.9 0.0 2.4 2 0 0 2 2 2 1 ArgK protein SbcCD_C PF13558.1 EWM26078.1 - 0.00027 20.7 2.2 1.3 9.0 0.3 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 EWM26078.1 - 0.00038 21.2 5.6 0.07 13.9 0.0 3.4 2 2 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 EWM26078.1 - 0.00039 20.2 0.0 0.98 9.2 0.0 2.6 2 0 0 2 2 2 2 Dynamin family AAA_28 PF13521.1 EWM26078.1 - 0.00068 19.6 0.4 1.7 8.5 0.4 3.9 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EWM26078.1 - 0.0011 19.2 0.1 0.92 9.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EWM26078.1 - 0.0025 17.9 3.2 2.4 8.3 0.4 3.8 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EWM26078.1 - 0.003 16.9 1.9 0.48 9.7 0.2 3.9 3 1 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 EWM26078.1 - 0.0056 16.8 0.0 0.91 9.7 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.1 EWM26078.1 - 0.0068 16.3 0.0 2.5 8.0 0.0 3.7 4 0 0 4 4 4 1 AAA domain FeoB_N PF02421.13 EWM26078.1 - 0.0082 15.4 0.1 0.2 10.9 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B NACHT PF05729.7 EWM26078.1 - 0.0095 15.6 0.9 7.9 6.1 0.0 3.3 3 0 0 3 3 3 0 NACHT domain AAA_10 PF12846.2 EWM26078.1 - 0.011 15.2 0.1 2.9 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain AAA_33 PF13671.1 EWM26078.1 - 0.011 15.6 0.1 5.1 6.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 EWM26078.1 - 0.019 14.6 0.0 3.6 7.2 0.0 2.5 3 0 0 3 3 2 0 Archaeal ATPase AAA_13 PF13166.1 EWM26078.1 - 0.021 13.3 0.0 8.1 4.7 0.0 3.1 4 0 0 4 4 4 0 AAA domain AAA PF00004.24 EWM26078.1 - 0.025 14.7 0.0 1.5 9.0 0.0 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.20 EWM26078.1 - 0.042 13.3 0.0 7.8 5.9 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain KAP_NTPase PF07693.9 EWM26078.1 - 0.067 12.1 0.1 5 6.0 0.0 2.4 2 1 0 2 2 2 0 KAP family P-loop domain MobB PF03205.9 EWM26078.1 - 0.087 12.5 2.2 4.8 6.8 0.1 2.8 2 1 1 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B TALPID3 PF15324.1 EWM26078.1 - 0.24 8.7 0.4 0.34 8.2 0.2 1.1 1 0 0 1 1 1 0 Hedgehog signalling target NB-ARC PF00931.17 EWM26078.1 - 0.44 9.3 2.3 1.8 7.3 0.1 2.5 2 1 0 2 2 2 0 NB-ARC domain DUF87 PF01935.12 EWM26078.1 - 1.1 9.0 5.8 22 4.7 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 cobW PF02492.14 EWM26079.1 - 2.5e-44 150.8 0.0 3.6e-44 150.3 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EWM26079.1 - 7e-18 64.1 0.0 4.9e-17 61.4 0.0 2.2 1 1 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_18 PF13238.1 EWM26079.1 - 0.00082 19.6 0.0 0.0017 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EWM26079.1 - 0.00085 19.0 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 EWM26079.1 - 0.0017 18.3 0.2 0.018 15.0 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain Viral_helicase1 PF01443.13 EWM26079.1 - 0.0027 17.2 0.1 0.024 14.1 0.0 2.2 1 1 1 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.1 EWM26079.1 - 0.0035 18.1 0.0 0.0092 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EWM26079.1 - 0.011 15.3 0.5 0.025 14.3 0.1 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EWM26079.1 - 0.024 14.8 0.0 0.054 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EWM26079.1 - 0.026 13.3 0.0 0.039 12.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.1 EWM26079.1 - 0.039 13.8 0.0 0.089 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EWM26079.1 - 0.058 12.2 0.0 0.096 11.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein UPF0079 PF02367.12 EWM26079.1 - 0.096 12.3 0.1 0.31 10.6 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 EWM26079.1 - 0.098 12.4 0.1 0.63 9.8 0.0 2.3 3 0 0 3 3 2 0 Part of AAA domain AAA_29 PF13555.1 EWM26079.1 - 0.11 12.0 0.0 0.34 10.4 0.0 1.8 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 EWM26079.1 - 0.11 11.9 0.1 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain BAF1_ABF1 PF04684.8 EWM26079.1 - 0.11 11.3 27.2 0.2 10.4 18.8 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor ABC_tran PF00005.22 EWM26079.1 - 0.13 12.5 0.7 0.3 11.3 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_14 PF13173.1 EWM26079.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EWM26079.1 - 0.18 10.5 0.9 0.94 8.2 0.2 2.3 2 1 0 2 2 2 0 ArgK protein Zip PF02535.17 EWM26079.1 - 1.7 7.5 20.8 3 6.7 14.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Trypsin_2 PF13365.1 EWM26080.1 - 4.2e-07 29.9 0.0 6.1e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Mcm10 PF09332.6 EWM26081.1 - 4.9e-16 59.0 2.1 7.7e-16 58.3 1.5 1.2 1 0 0 1 1 1 1 Mcm10 replication factor Lar_restr_allev PF14354.1 EWM26081.1 - 0.1 12.9 1.4 4 7.8 0.2 2.7 2 0 0 2 2 2 0 Restriction alleviation protein Lar DENN PF02141.16 EWM26082.1 - 7.3e-29 100.8 0.1 1.2e-28 100.0 0.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain ENTH PF01417.15 EWM26082.1 - 4.5e-10 39.4 0.0 7.3e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 ENTH domain dDENN PF03455.14 EWM26082.1 - 0.067 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 dDENN domain DnaJ PF00226.26 EWM26083.1 - 8.2e-22 76.7 1.6 1.5e-21 75.8 1.1 1.5 1 0 0 1 1 1 1 DnaJ domain Phage_head_fibr PF11133.3 EWM26083.1 - 0.00015 21.0 0.0 0.00024 20.4 0.0 1.3 1 0 0 1 1 1 1 Head fiber protein Snapin_Pallidin PF14712.1 EWM26083.1 - 0.21 11.9 5.4 0.33 11.2 3.8 1.3 1 0 0 1 1 1 0 Snapin/Pallidin PEP_mutase PF13714.1 EWM26084.1 - 1.2e-44 152.3 0.2 1.5e-44 152.0 0.2 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EWM26084.1 - 1.6e-10 39.8 0.4 3.2e-10 38.8 0.3 1.4 1 0 0 1 1 1 1 Isocitrate lyase family ComA PF02679.10 EWM26084.1 - 0.11 11.4 0.1 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) Cupin_4 PF08007.7 EWM26085.1 - 2.5e-68 230.6 0.0 2.4e-67 227.4 0.0 2.0 1 1 0 1 1 1 1 Cupin superfamily protein Armet PF10208.4 EWM26085.1 - 5.3e-31 107.3 10.0 8e-31 106.7 7.0 1.3 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding AraC_binding PF02311.14 EWM26085.1 - 0.00011 21.9 0.0 0.00024 20.7 0.0 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain SAP PF02037.22 EWM26085.1 - 0.00015 21.1 0.1 0.00046 19.6 0.1 1.9 1 0 0 1 1 1 1 SAP domain HeH PF12949.2 EWM26085.1 - 0.027 14.0 0.9 0.059 12.9 0.0 2.0 2 0 0 2 2 2 0 HeH/LEM domain Cupin_2 PF07883.6 EWM26085.1 - 0.042 13.3 0.0 0.26 10.8 0.0 2.3 3 0 0 3 3 3 0 Cupin domain HAUS-augmin3 PF14932.1 EWM26086.1 - 0.014 14.5 12.5 0.024 13.8 8.6 1.4 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 Dzip-like_N PF13815.1 EWM26086.1 - 0.4 10.4 6.9 2.4 7.9 1.4 2.5 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Glyco_hydro_77 PF02446.12 EWM26086.1 - 0.79 8.2 3.2 0.97 7.9 2.2 1.1 1 0 0 1 1 1 0 4-alpha-glucanotransferase VIT1 PF01988.14 EWM26086.1 - 2.7 7.4 6.5 0.43 10.0 1.6 1.7 1 1 1 2 2 2 0 VIT family Sec8_exocyst PF04048.9 EWM26087.1 - 0.039 13.5 6.5 0.017 14.7 1.5 2.6 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain Sec8_exocyst PF04048.9 EWM26088.1 - 0.019 14.6 1.9 0.019 14.6 1.3 2.6 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain Mnd1 PF03962.10 EWM26088.1 - 0.36 10.4 18.3 0.085 12.5 1.5 2.7 2 0 0 2 2 2 0 Mnd1 family APG6 PF04111.7 EWM26088.1 - 1.3 7.9 20.6 0.27 10.2 3.7 2.3 2 0 0 2 2 2 0 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 EWM26088.1 - 4.6 7.0 24.9 0.59 9.8 5.0 3.1 2 2 1 3 3 3 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 EWM26088.1 - 5.6 6.5 18.3 8.4 5.9 2.1 2.6 2 0 0 2 2 2 0 IncA protein YEATS PF03366.11 EWM26089.1 - 4.8e-24 83.8 0.5 8.1e-24 83.1 0.3 1.4 1 0 0 1 1 1 1 YEATS family CDC27 PF09507.5 EWM26089.1 - 0.013 14.7 1.2 0.021 14.0 0.8 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PAXNEB PF05625.6 EWM26090.1 - 1.2e-61 208.5 0.0 1.6e-61 208.1 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein Chorismate_bind PF00425.13 EWM26091.1 - 3.4e-62 210.1 0.0 4.2e-31 108.2 0.0 2.3 2 0 0 2 2 2 2 chorismate binding enzyme TPP_enzyme_N PF02776.13 EWM26091.1 - 1.7e-31 109.0 0.6 1.7e-31 109.0 0.4 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Abhydrolase_6 PF12697.2 EWM26091.1 - 4.5e-23 82.3 8.3 4.5e-23 82.3 5.7 3.4 3 1 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EWM26091.1 - 1.4e-12 47.7 0.2 5.4e-12 45.7 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EWM26091.1 - 6.6e-10 38.9 0.1 9.9e-09 35.1 0.0 3.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family MR_MLE PF01188.16 EWM26091.1 - 1.1e-07 32.2 0.0 4.4e-07 30.3 0.0 2.1 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Thioesterase PF00975.15 EWM26091.1 - 0.0044 17.2 0.1 0.01 16.0 0.1 1.5 1 0 0 1 1 1 1 Thioesterase domain TPP_enzyme_M PF00205.17 EWM26091.1 - 0.0045 16.7 0.0 0.015 15.0 0.0 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain MR_MLE_C PF13378.1 EWM26091.1 - 0.0048 16.8 0.0 0.02 14.8 0.0 2.0 1 0 0 1 1 1 1 Enolase C-terminal domain-like Esterase PF00756.15 EWM26091.1 - 0.0057 16.1 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.8 EWM26091.1 - 0.0088 15.6 0.0 0.023 14.2 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2048 PF09752.4 EWM26091.1 - 0.033 13.0 0.1 0.065 12.1 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) DLH PF01738.13 EWM26091.1 - 0.087 12.0 0.0 0.3 10.3 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family Ndr PF03096.9 EWM26091.1 - 0.15 10.4 0.0 0.26 9.7 0.0 1.2 1 0 0 1 1 1 0 Ndr family BAAT_C PF08840.6 EWM26091.1 - 0.34 10.5 0.0 0.67 9.6 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal UPF0227 PF05728.7 EWM26091.1 - 0.5 10.0 0.0 0.91 9.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) PLAC8 PF04749.12 EWM26092.1 - 4.2e-13 49.7 2.2 6.9e-13 49.0 1.5 1.3 1 0 0 1 1 1 1 PLAC8 family DUF1129 PF06570.6 EWM26092.1 - 0.0069 15.7 0.1 0.0096 15.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1129) Tic20 PF09685.5 EWM26092.1 - 0.25 11.3 3.6 0.5 10.3 2.5 1.4 1 0 0 1 1 1 0 Tic20-like protein WD40 PF00400.27 EWM26094.1 - 2.8e-25 87.2 10.3 1.6e-06 27.7 0.1 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.6 EWM26094.1 - 0.036 13.7 0.0 6.5 6.4 0.0 2.8 2 2 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EWM26094.1 - 0.096 12.3 0.0 33 4.2 0.0 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat CDC45 PF02724.9 EWM26094.1 - 0.54 8.2 4.7 0.89 7.5 3.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Malic_M PF03949.10 EWM26095.1 - 9.6e-77 257.9 0.2 1.5e-76 257.3 0.2 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EWM26095.1 - 5.5e-65 218.3 0.0 1.1e-64 217.4 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF3082 PF11282.3 EWM26095.1 - 0.17 11.9 1.2 0.37 10.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3082) DUF4485 PF14846.1 EWM26096.1 - 0.0072 16.0 0.7 0.025 14.2 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4485) DUF3677 PF12432.3 EWM26096.1 - 0.13 12.7 0.3 0.99 9.8 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3677) S1 PF00575.18 EWM26097.1 - 1.5e-41 140.2 2.6 8.5e-17 61.0 0.2 3.3 3 0 0 3 3 3 3 S1 RNA binding domain DUF866 PF05907.8 EWM26098.1 - 3.6e-21 75.3 0.0 5.3e-21 74.7 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) BPL_LplA_LipB PF03099.14 EWM26099.1 - 3.2e-15 56.2 0.1 6.2e-15 55.3 0.1 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family adh_short PF00106.20 EWM26100.1 - 1.3e-17 64.2 0.1 2.1e-17 63.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EWM26100.1 - 4e-06 26.9 0.1 1.1e-05 25.5 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding KR PF08659.5 EWM26100.1 - 0.00019 21.1 0.1 0.00031 20.4 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EWM26100.1 - 0.041 13.3 0.0 0.058 12.8 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EWM26100.1 - 0.082 12.6 1.0 0.19 11.5 0.7 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ETRAMP PF09716.5 EWM26100.1 - 0.096 12.6 0.3 0.94 9.4 0.0 2.6 4 0 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) zf-HIT PF04438.11 EWM26102.1 - 2e-08 33.7 14.6 3.1e-08 33.1 10.1 1.3 1 0 0 1 1 1 1 HIT zinc finger DUF3799 PF12684.2 EWM26102.1 - 0.05 12.9 0.3 0.076 12.3 0.2 1.2 1 0 0 1 1 1 0 PDDEXK-like domain of unknown function (DUF3799) DUF4661 PF15576.1 EWM26102.1 - 0.25 10.9 3.3 0.35 10.4 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) zf-MYND PF01753.13 EWM26102.1 - 1.6 8.7 12.7 3.1 7.7 8.8 1.5 1 0 0 1 1 1 0 MYND finger PHD PF00628.24 EWM26103.1 - 5.6e-10 38.7 7.0 1.2e-09 37.7 4.9 1.5 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 EWM26103.1 - 9.5e-06 25.2 5.2 2e-05 24.2 3.0 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 PHD_2 PF13831.1 EWM26103.1 - 0.0007 18.8 7.9 0.0023 17.1 5.5 2.0 1 1 0 1 1 1 1 PHD-finger C1_1 PF00130.17 EWM26103.1 - 0.043 13.5 0.5 0.043 13.5 0.4 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) OrfB_Zn_ribbon PF07282.6 EWM26103.1 - 0.07 12.7 6.1 8.1 6.1 2.5 2.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain YlqD PF11068.3 EWM26103.1 - 0.13 12.3 1.6 0.2 11.6 0.0 2.1 2 0 0 2 2 2 0 YlqD protein DEAD PF00270.24 EWM26104.1 - 1.8e-44 151.2 1.4 1.8e-44 151.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EWM26104.1 - 1.3e-21 76.1 0.0 2.9e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EWM26104.1 - 2.3e-21 75.1 0.3 4.8e-21 74.0 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) AAA_22 PF13401.1 EWM26104.1 - 0.027 14.6 4.0 0.03 14.4 0.1 2.8 3 1 0 3 3 3 0 AAA domain ResIII PF04851.10 EWM26104.1 - 0.034 13.9 3.6 0.06 13.1 0.0 2.8 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Zot PF05707.7 EWM26104.1 - 1.2 8.5 4.2 7.6 5.9 0.0 3.7 3 2 1 4 4 4 0 Zonular occludens toxin (Zot) Hid1 PF12722.2 EWM26104.1 - 2.7 5.5 9.6 4.1 4.9 6.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein BOP1NT PF08145.7 EWM26104.1 - 3.1 7.4 13.2 17 5.0 3.8 3.3 4 0 0 4 4 4 0 BOP1NT (NUC169) domain PALP PF00291.20 EWM26105.1 - 8.5e-61 205.8 0.0 1.2e-60 205.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 EWM26105.1 - 2.2e-08 33.7 0.2 1.6e-05 24.5 0.0 3.4 2 1 0 2 2 2 2 CBS domain RmlD_sub_bind PF04321.12 EWM26108.1 - 4.8e-46 156.9 0.0 2.9e-42 144.5 0.0 2.0 2 0 0 2 2 2 2 RmlD substrate binding domain Epimerase PF01370.16 EWM26108.1 - 1.4e-21 77.0 0.0 2.3e-21 76.3 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EWM26108.1 - 1.1e-09 38.6 0.1 1.5e-09 38.1 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EWM26108.1 - 9.4e-05 21.4 0.0 0.0012 17.8 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 EWM26108.1 - 0.0091 14.9 0.1 0.26 10.1 0.1 2.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EWM26108.1 - 4.1 7.2 7.7 4.8 7.0 2.6 2.7 2 1 0 2 2 2 0 short chain dehydrogenase Nol1_Nop2_Fmu PF01189.12 EWM26109.1 - 2.6e-27 95.9 0.0 6e-15 55.3 0.0 3.9 4 0 0 4 4 4 2 NOL1/NOP2/sun family FtsJ PF01728.14 EWM26109.1 - 0.017 15.1 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase AMP-binding PF00501.23 EWM26110.1 - 1.6e-72 244.1 0.1 2e-72 243.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ELM2 PF01448.19 EWM26111.1 - 0.0069 17.0 0.0 0.023 15.3 0.0 1.9 1 1 0 1 1 1 1 ELM2 domain PLRV_ORF5 PF01690.12 EWM26111.1 - 8.7 5.3 7.7 16 4.4 5.4 1.4 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein WD40 PF00400.27 EWM26112.1 - 1.4e-05 24.7 0.5 0.00078 19.2 0.1 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat IQ PF00612.22 EWM26112.1 - 0.19 11.4 1.8 0.8 9.5 1.3 2.2 1 0 0 1 1 1 0 IQ calmodulin-binding motif zf-RING_5 PF14634.1 EWM26112.1 - 0.31 10.8 3.3 0.91 9.2 2.3 1.8 1 0 0 1 1 1 0 zinc-RING finger domain DUF1280 PF06918.9 EWM26112.1 - 0.81 8.8 0.0 1.4 8.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1280) NPIP PF06409.6 EWM26112.1 - 1.3 7.7 3.0 14 4.3 0.6 2.3 2 0 0 2 2 2 0 Nuclear pore complex interacting protein (NPIP) zf-Apc11 PF12861.2 EWM26112.1 - 9.5 6.1 8.3 0.67 9.8 0.6 2.6 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger PGK PF00162.14 EWM26113.1 - 1.5e-159 530.7 2.2 8.6e-158 524.9 1.2 2.0 2 0 0 2 2 2 2 Phosphoglycerate kinase TMP-TENI PF02581.12 EWM26113.1 - 0.0022 17.1 0.2 0.021 13.9 0.0 2.2 2 0 0 2 2 2 1 Thiamine monophosphate synthase/TENI Telomere_reg-2 PF10193.4 EWM26113.1 - 0.064 13.5 0.1 0.18 12.0 0.0 1.8 2 0 0 2 2 2 0 Telomere length regulation protein OmpH PF03938.9 EWM26113.1 - 0.2 11.5 1.3 0.23 11.4 0.1 1.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) PGK PF00162.14 EWM26114.1 - 1e-70 238.2 0.3 2.2e-63 214.1 0.0 3.0 3 0 0 3 3 3 3 Phosphoglycerate kinase Telomere_reg-2 PF10193.4 EWM26114.1 - 0.057 13.6 0.1 0.15 12.3 0.0 1.7 2 0 0 2 2 2 0 Telomere length regulation protein WD40 PF00400.27 EWM26115.1 - 7.4e-05 22.4 0.1 0.00032 20.4 0.0 2.2 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF2610 PF11020.3 EWM26115.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2610) PQQ_3 PF13570.1 EWM26115.1 - 0.24 11.7 2.2 34 4.9 0.1 3.8 3 0 0 3 3 3 0 PQQ-like domain ATP-synt_10 PF05176.9 EWM26116.1 - 2.5e-40 138.3 0.0 3e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein FlgM PF04316.8 EWM26116.1 - 0.061 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM Mito_carr PF00153.22 EWM26117.1 - 5.2e-40 135.0 0.1 3.4e-13 49.1 0.0 3.7 4 1 0 4 4 4 3 Mitochondrial carrier protein Trypsin_2 PF13365.1 EWM26118.1 - 0.00069 19.6 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Methyltransf_11 PF08241.7 EWM26119.1 - 1.6e-15 57.3 0.0 3.3e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM26119.1 - 1.2e-09 38.1 0.0 2.3e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM26119.1 - 1.4e-09 38.5 0.0 3.7e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EWM26119.1 - 1.8e-08 33.7 0.0 2.7e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EWM26119.1 - 3.9e-06 27.2 0.0 7.3e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM26119.1 - 4.4e-05 23.0 0.0 0.00014 21.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM26119.1 - 0.00034 20.9 0.0 0.0013 19.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM26119.1 - 0.0024 17.8 0.1 0.0075 16.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EWM26119.1 - 0.037 13.9 0.0 0.36 10.8 0.0 2.2 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_8 PF05148.10 EWM26119.1 - 0.042 13.4 0.0 0.1 12.2 0.0 1.6 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltrn_RNA_3 PF02598.12 EWM26120.1 - 5.9e-85 285.1 0.0 7.1e-85 284.8 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.14 EWM26120.1 - 0.079 12.8 0.0 5 6.9 0.0 2.4 2 0 0 2 2 2 0 SpoU rRNA Methylase family Prenyltrans PF00432.16 EWM26121.1 - 1.3e-44 149.4 15.7 3.3e-10 39.3 0.3 5.4 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EWM26121.1 - 6.1e-23 81.3 0.0 1.4e-16 60.9 0.0 3.4 2 1 1 3 3 3 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 EWM26121.1 - 1.9e-05 24.6 0.0 0.29 11.1 0.0 3.6 2 1 1 3 3 3 2 Prenyltransferase-like Prenyltrans PF00432.16 EWM26122.1 - 5.3e-45 150.6 15.7 2.7e-10 39.6 0.3 5.3 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EWM26122.1 - 3.1e-23 82.3 0.0 1e-16 61.3 0.0 3.3 2 1 1 3 3 3 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 EWM26122.1 - 1e-05 25.5 0.0 0.23 11.5 0.0 3.6 2 1 1 3 3 3 2 Prenyltransferase-like Cpn60_TCP1 PF00118.19 EWM26124.1 - 1.3e-102 343.8 3.9 1.6e-102 343.6 2.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF4506 PF14958.1 EWM26125.1 - 0.034 13.7 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4506) ClpS PF02617.12 EWM26126.1 - 1.2e-15 56.9 0.1 2.3e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Kinesin PF00225.18 EWM26127.1 - 5.1e-94 314.7 0.0 1.3e-93 313.3 0.0 1.7 1 0 0 1 1 1 1 Kinesin motor domain PH PF00169.24 EWM26127.1 - 6.8e-10 39.0 0.0 1.7e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_6 PF15406.1 EWM26127.1 - 0.0089 16.0 0.0 0.029 14.4 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 EWM26127.1 - 0.087 13.0 0.5 0.52 10.5 0.4 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain Nop14 PF04147.7 EWM26127.1 - 2.1 6.1 19.1 3.2 5.5 13.2 1.2 1 0 0 1 1 1 0 Nop14-like family DUF3395 PF11875.3 EWM26128.1 - 9.3e-23 80.5 0.0 1.7e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 EWM26128.1 - 1.2e-17 63.4 0.4 2.1e-17 62.5 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain LRR_4 PF12799.2 EWM26129.1 - 1.4e-14 53.2 16.9 5.3e-09 35.4 3.1 2.9 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EWM26129.1 - 6.3e-12 45.0 8.8 2.5e-11 43.1 4.3 2.6 2 1 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.28 EWM26129.1 - 1.8e-08 33.2 10.9 0.0022 17.7 0.7 4.2 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 EWM26129.1 - 8.7e-05 22.1 13.6 0.11 12.7 0.6 4.4 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 EWM26129.1 - 0.0059 16.5 8.2 0.47 10.6 0.1 4.0 4 0 0 4 4 4 2 Leucine Rich repeat LRR_9 PF14580.1 EWM26129.1 - 0.031 13.8 0.5 0.057 12.9 0.2 1.5 1 1 0 1 1 1 0 Leucine-rich repeat EF-hand_1 PF00036.27 EWM26131.1 - 5.3e-34 112.9 9.4 2.4e-07 29.5 0.2 7.6 7 0 0 7 7 7 6 EF hand Metallophos PF00149.23 EWM26131.1 - 4.7e-31 107.7 0.0 7.2e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_7 PF13499.1 EWM26131.1 - 7.8e-30 102.8 9.6 4e-11 42.8 0.8 4.7 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_8 PF13833.1 EWM26131.1 - 2.2e-25 88.0 10.9 3.6e-06 26.4 0.1 6.4 4 2 2 6 6 6 5 EF-hand domain pair EF-hand_6 PF13405.1 EWM26131.1 - 6.8e-23 78.4 10.9 4.7e-05 22.9 0.2 7.3 7 0 0 7 7 7 5 EF-hand domain EF-hand_5 PF13202.1 EWM26131.1 - 2.6e-20 70.7 11.0 8.9e-05 21.6 0.3 6.6 6 0 0 6 6 6 4 EF hand CAP_GLY PF01302.20 EWM26131.1 - 1.5e-17 63.0 0.2 1.1e-16 60.2 0.0 2.5 3 0 0 3 3 3 1 CAP-Gly domain PPP5 PF08321.7 EWM26131.1 - 1.9e-07 31.0 0.0 5.9e-07 29.4 0.0 1.9 1 0 0 1 1 1 1 PPP5 TPR repeat region SPARC_Ca_bdg PF10591.4 EWM26131.1 - 6.8e-06 26.0 0.4 1 9.3 0.0 4.1 4 0 0 4 4 4 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EWM26131.1 - 1.8e-05 24.3 5.8 2.9 7.6 0.0 5.4 4 2 2 6 6 6 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EWM26131.1 - 3.4e-05 23.6 0.2 0.015 15.1 0.0 3.9 4 0 0 4 4 4 1 EF-hand domain DUF1880 PF08976.6 EWM26131.1 - 0.051 13.7 0.1 3.2 7.8 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF1880) Mpv17_PMP22 PF04117.7 EWM26132.1 - 1.6e-22 78.9 0.1 2.7e-22 78.1 0.1 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Mpv17_PMP22 PF04117.7 EWM26133.1 - 1.6e-22 78.9 0.1 2.7e-22 78.1 0.1 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Ribosomal_L11_N PF03946.9 EWM26134.1 - 1.5e-16 59.6 0.2 2.1e-16 59.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EWM26134.1 - 2.1e-12 47.0 0.7 4.3e-12 45.9 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain CorC_HlyC PF03471.12 EWM26134.1 - 0.038 13.7 0.0 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 Transporter associated domain AAA_18 PF13238.1 EWM26135.1 - 3.5e-07 30.5 0.0 1.8e-06 28.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EWM26135.1 - 5.8e-07 30.3 0.0 1.4e-06 29.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 EWM26135.1 - 1.4e-05 24.7 0.0 1.9e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family KTI12 PF08433.5 EWM26135.1 - 1.6e-05 24.3 0.0 2.6e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EWM26135.1 - 4.3e-05 23.4 0.2 0.00061 19.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain ArgK PF03308.11 EWM26135.1 - 0.00025 19.9 0.0 0.00047 19.0 0.0 1.5 1 0 0 1 1 1 1 ArgK protein Zeta_toxin PF06414.7 EWM26135.1 - 0.00094 18.3 0.0 0.01 14.9 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.1 EWM26135.1 - 0.0013 18.7 0.0 0.0029 17.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain MobB PF03205.9 EWM26135.1 - 0.0025 17.5 0.0 0.0047 16.6 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B APS_kinase PF01583.15 EWM26135.1 - 0.0039 16.8 0.0 0.022 14.4 0.0 2.0 2 0 0 2 2 2 1 Adenylylsulphate kinase NTPase_1 PF03266.10 EWM26135.1 - 0.014 15.1 0.1 0.042 13.5 0.0 1.8 2 0 0 2 2 2 0 NTPase ATP_bind_1 PF03029.12 EWM26135.1 - 0.017 14.6 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.1 EWM26135.1 - 0.02 14.8 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ADK PF00406.17 EWM26135.1 - 0.043 13.7 0.0 5.2 6.9 0.0 2.2 2 0 0 2 2 2 0 Adenylate kinase AAA_22 PF13401.1 EWM26135.1 - 0.067 13.3 0.0 0.18 11.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EWM26135.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Miro PF08477.8 EWM26135.1 - 0.14 12.6 0.0 0.28 11.6 0.0 1.6 1 1 0 1 1 1 0 Miro-like protein IGPS PF00218.16 EWM26136.1 - 5e-80 268.2 0.2 9.3e-80 267.3 0.1 1.4 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 EWM26136.1 - 2.1e-41 141.6 0.1 1.7e-38 132.1 0.0 2.4 2 1 0 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase QRPTase_C PF01729.14 EWM26136.1 - 0.023 14.2 0.2 0.12 11.8 0.0 2.2 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, C-terminal domain PPR_2 PF13041.1 EWM26138.1 - 1.2e-43 146.8 0.0 5.6e-08 32.6 0.0 12.5 9 4 5 14 14 14 8 PPR repeat family PPR PF01535.15 EWM26138.1 - 7e-43 141.6 16.0 0.00053 19.7 0.1 14.0 14 0 0 14 14 14 9 PPR repeat PPR_3 PF13812.1 EWM26138.1 - 1.8e-42 140.0 19.6 5.8e-06 26.1 0.1 14.0 16 0 0 16 16 16 8 Pentatricopeptide repeat domain PPR_1 PF12854.2 EWM26138.1 - 6.7e-22 76.6 15.9 1.6e-05 24.2 0.0 9.8 9 1 1 10 10 10 6 PPR repeat Apc3 PF12895.2 EWM26138.1 - 1.3e-06 28.4 0.0 0.96 9.6 0.0 5.9 6 0 0 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EWM26138.1 - 3.4e-06 27.3 19.1 0.51 10.7 0.0 7.7 8 1 1 9 9 8 2 Tetratricopeptide repeat TPR_12 PF13424.1 EWM26138.1 - 4.6e-06 26.4 8.8 1.9 8.4 0.4 7.4 6 1 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.1 EWM26138.1 - 3e-05 24.2 39.6 2.4 9.0 0.3 12.4 14 1 1 15 15 13 1 Tetratricopeptide repeat BTAD PF03704.12 EWM26138.1 - 9.8e-05 22.6 23.8 0.37 11.0 0.1 7.0 6 1 0 6 6 6 2 Bacterial transcriptional activator domain TPR_16 PF13432.1 EWM26138.1 - 0.0031 18.1 27.7 0.17 12.6 1.5 8.0 7 2 1 8 8 7 1 Tetratricopeptide repeat TPR_4 PF07721.9 EWM26138.1 - 0.014 15.7 52.8 0.89 10.1 1.0 12.0 12 0 0 12 12 12 0 Tetratricopeptide repeat TPR_15 PF13429.1 EWM26138.1 - 0.014 14.4 3.5 1.3 8.0 0.0 4.5 4 2 0 5 5 5 0 Tetratricopeptide repeat HEAT_PBS PF03130.11 EWM26138.1 - 0.16 12.5 6.3 7.9 7.2 0.0 5.6 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat UbiA PF01040.13 EWM26139.1 - 3.6e-21 75.5 17.4 5.2e-21 75.0 12.1 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Pkinase PF00069.20 EWM26141.1 - 9.6e-62 208.4 0.0 1.3e-61 208.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM26141.1 - 2.2e-19 69.5 0.0 3.2e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Glyco_trans_1_4 PF13692.1 EWM26141.1 - 6e-18 65.3 0.0 4.1e-17 62.5 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 APH PF01636.18 EWM26141.1 - 3e-07 30.4 0.0 0.00024 20.9 0.0 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Glycos_transf_1 PF00534.15 EWM26141.1 - 1.5e-06 27.7 0.0 2.8e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EWM26141.1 - 1.6e-06 28.3 0.1 4.2e-06 26.9 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Choline_kinase PF01633.15 EWM26141.1 - 0.02 14.4 0.1 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Glyco_trans_1_2 PF13524.1 EWM26141.1 - 0.14 12.4 0.2 1 9.6 0.0 2.4 3 0 0 3 3 3 0 Glycosyl transferases group 1 Coatomer_WDAD PF04053.9 EWM26143.1 - 2.1e-120 402.5 0.0 3.3e-120 401.8 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 EWM26143.1 - 4e-87 292.4 4.6 1.3e-86 290.8 3.2 1.7 1 1 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EWM26143.1 - 3.1e-57 188.5 11.0 1.9e-11 43.3 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EWM26143.1 - 0.00026 19.2 4.1 0.0027 15.9 0.1 2.8 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EWM26143.1 - 0.011 14.4 0.9 3.7 6.2 0.0 3.7 3 1 1 4 4 4 0 Nup133 N terminal like zf-LSD1 PF06943.7 EWM26143.1 - 0.061 12.9 4.8 0.15 11.7 3.3 1.6 1 0 0 1 1 1 0 LSD1 zinc finger RNA_pol PF00940.14 EWM26144.1 - 8.6e-154 511.8 0.0 1.1e-153 511.5 0.0 1.1 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EWM26144.1 - 3.9e-49 167.6 0.0 7.4e-25 87.8 0.0 2.6 2 0 0 2 2 2 2 DNA-directed RNA polymerase N-terminal zf-MIZ PF02891.15 EWM26145.1 - 4.4e-18 64.5 0.2 1.3e-17 62.9 0.1 1.9 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger PINIT PF14324.1 EWM26145.1 - 3.9e-06 27.0 0.0 9.3e-06 25.7 0.0 1.6 1 1 0 1 1 1 1 PINIT domain SAP PF02037.22 EWM26145.1 - 0.0001 21.7 0.0 0.00021 20.7 0.0 1.6 1 0 0 1 1 1 1 SAP domain PHD_2 PF13831.1 EWM26145.1 - 0.0023 17.1 2.3 0.0023 17.1 1.6 2.4 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 EWM26145.1 - 0.0038 16.8 13.4 0.0059 16.2 4.9 2.5 2 0 0 2 2 2 1 PHD-finger zf-Nse PF11789.3 EWM26145.1 - 0.0058 16.1 0.0 0.017 14.6 0.0 1.9 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit C1_1 PF00130.17 EWM26145.1 - 1.7 8.3 10.7 0.35 10.6 2.9 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.6 EWM26145.1 - 5.8 6.9 11.4 0.3 11.1 2.8 2.6 3 0 0 3 3 3 0 RING-like domain Pkinase_Tyr PF07714.12 EWM26146.1 - 8.8e-11 41.3 0.0 1.9e-10 40.2 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 EWM26146.1 - 1.4e-10 40.8 0.0 3.6e-09 36.1 0.0 2.1 1 1 1 2 2 2 1 Protein kinase domain HEAT PF02985.17 EWM26146.1 - 2.5e-07 30.2 6.5 1.6 8.9 0.1 5.9 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.1 EWM26146.1 - 0.026 14.8 0.4 8.5 6.7 0.0 3.2 2 1 0 3 3 3 0 HEAT repeats CLASP_N PF12348.3 EWM26146.1 - 0.13 11.5 0.1 2.1 7.6 0.1 2.1 1 1 1 2 2 2 0 CLASP N terminal ILVD_EDD PF00920.16 EWM26147.1 - 4.7e-215 714.9 0.7 5.5e-215 714.7 0.5 1.0 1 0 0 1 1 1 1 Dehydratase family MR_MLE_C PF13378.1 EWM26147.1 - 0.034 14.1 0.1 4.7 7.2 0.0 2.5 2 0 0 2 2 2 0 Enolase C-terminal domain-like zf-C2HC5 PF06221.8 EWM26148.1 - 7.7e-11 41.5 8.3 1.7e-10 40.5 5.7 1.5 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Cir_N PF10197.4 EWM26148.1 - 0.014 15.4 2.7 0.014 15.4 1.9 2.9 2 0 0 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR zf-C2HC5 PF06221.8 EWM26149.1 - 7.7e-11 41.5 8.3 1.7e-10 40.5 5.7 1.5 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Cir_N PF10197.4 EWM26149.1 - 0.014 15.4 2.7 0.014 15.4 1.9 2.9 2 0 0 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR SPX PF03105.14 EWM26150.1 - 4.4e-25 88.9 0.0 2.9e-12 46.9 0.0 2.6 2 1 1 3 3 3 2 SPX domain GBP PF02263.14 EWM26151.1 - 3.7e-50 170.3 0.3 2.1e-49 167.9 0.2 1.9 1 1 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.9 EWM26151.1 - 9.4e-07 28.2 0.3 1.6e-06 27.5 0.2 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain HEAT PF02985.17 EWM26152.1 - 6.5e-32 106.7 43.7 0.004 17.1 0.1 13.9 15 0 0 15 15 15 11 HEAT repeat HEAT_2 PF13646.1 EWM26152.1 - 1.7e-30 105.1 21.6 3.2e-09 36.9 0.1 7.0 3 2 4 7 7 7 7 HEAT repeats Vac14_Fab1_bd PF12755.2 EWM26152.1 - 4.1e-07 30.2 0.0 0.29 11.5 0.0 5.5 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EWM26152.1 - 3.2e-06 27.4 35.5 4.7 7.8 0.1 10.7 11 2 2 13 13 13 4 HEAT-like repeat Adaptin_N PF01602.15 EWM26152.1 - 1.4e-05 23.6 0.4 0.00032 19.1 0.0 2.8 1 1 1 2 2 2 2 Adaptin N terminal region CLASP_N PF12348.3 EWM26152.1 - 5e-05 22.7 0.1 0.49 9.7 0.0 4.9 1 1 5 6 6 6 1 CLASP N terminal Arm PF00514.18 EWM26152.1 - 0.077 12.8 11.3 10 6.0 0.1 6.4 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat Proteasome PF00227.21 EWM26153.1 - 4.3e-60 202.2 0.2 5.7e-60 201.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EWM26153.1 - 6.5e-15 54.1 0.1 1.3e-14 53.2 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature YIF1 PF03878.10 EWM26155.1 - 2.8e-49 167.4 3.4 4.3e-49 166.8 2.3 1.2 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 EWM26155.1 - 0.0016 17.9 8.0 0.0028 17.1 4.3 2.0 1 1 1 2 2 2 1 Yip1 domain AAA_16 PF13191.1 EWM26156.1 - 0.0027 17.7 0.0 0.0096 15.9 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain Glyco_hydro_9 PF00759.14 EWM26157.1 - 2.1e-128 429.0 8.1 2.4e-128 428.8 5.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Asn_synthase PF00733.16 EWM26160.1 - 5.8e-40 137.3 0.0 1.3e-26 93.6 0.0 2.2 2 0 0 2 2 2 2 Asparagine synthase GATase_7 PF13537.1 EWM26160.1 - 1.4e-06 27.9 0.0 2.1e-05 24.2 0.0 2.3 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EWM26160.1 - 0.018 14.9 0.0 0.16 11.9 0.0 2.6 2 1 0 2 2 2 0 Glutamine amidotransferase domain Methyltransf_23 PF13489.1 EWM26161.1 - 1.1e-10 41.4 0.0 2.3e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM26161.1 - 5.8e-08 33.1 0.0 1.9e-07 31.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM26161.1 - 3.1e-06 27.5 0.0 7.4e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM26161.1 - 4.1e-05 23.2 0.0 7.9e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM26161.1 - 4.7e-05 23.9 0.0 0.00015 22.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EWM26161.1 - 0.0018 17.6 0.0 0.018 14.4 0.0 2.1 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW E1-N PF14463.1 EWM26161.1 - 0.047 13.2 0.3 0.099 12.2 0.2 1.5 1 0 0 1 1 1 0 E1 N-terminal domain Ubie_methyltran PF01209.13 EWM26161.1 - 0.087 11.9 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DnaJ PF00226.26 EWM26163.1 - 4.4e-17 61.5 0.6 2.7e-16 59.0 0.1 2.5 2 0 0 2 2 2 1 DnaJ domain HsbA PF12296.3 EWM26163.1 - 0.2 11.5 11.3 0.17 11.7 1.0 2.8 2 1 0 2 2 2 0 Hydrophobic surface binding protein A Helitron_like_N PF14214.1 EWM26163.1 - 0.75 9.5 5.7 0.11 12.1 0.8 1.9 2 0 0 2 2 2 0 Helitron helicase-like domain at N-terminus Fib_alpha PF08702.5 EWM26163.1 - 8.3 6.5 9.5 14 5.8 0.3 2.7 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF4336 PF14234.1 EWM26165.1 - 4.9e-22 78.4 0.3 1.4e-17 63.8 0.1 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) UQ_con PF00179.21 EWM26166.1 - 0.00015 21.2 0.0 0.00024 20.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EWM26166.1 - 0.015 15.1 0.0 0.048 13.5 0.0 1.5 1 1 0 1 1 1 0 RWD domain FKBP_C PF00254.23 EWM26168.1 - 2.7e-13 49.7 0.0 5.5e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase CS PF04969.11 EWM26168.1 - 1.5e-10 41.4 0.1 2.7e-10 40.6 0.1 1.5 1 0 0 1 1 1 1 CS domain VRR_NUC PF08774.6 EWM26169.1 - 2.5e-17 62.7 0.0 1.5e-16 60.2 0.0 2.3 2 0 0 2 2 2 1 VRR-NUC domain CS PF04969.11 EWM26170.1 - 0.12 12.8 0.0 0.16 12.5 0.0 1.1 1 0 0 1 1 1 0 CS domain RRM_1 PF00076.17 EWM26171.1 - 3.5e-18 65.0 0.1 5.4e-18 64.3 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM26171.1 - 5.4e-15 55.1 0.1 9.3e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.3 EWM26171.1 - 1.7e-09 37.6 0.3 2.9e-09 36.9 0.2 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_5 PF13893.1 EWM26171.1 - 1.3e-06 28.1 0.0 2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fucokinase PF07959.7 EWM26172.1 - 2.9e-27 95.2 0.0 7.2e-27 93.9 0.0 1.7 2 0 0 2 2 2 1 L-fucokinase GHMP_kinases_C PF08544.8 EWM26172.1 - 3.9e-09 36.5 0.0 1.7e-08 34.5 0.0 2.2 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 EWM26172.1 - 1.1e-05 25.4 0.3 1.1e-05 25.4 0.2 2.4 3 0 0 3 3 3 1 GHMP kinases N terminal domain AAA_22 PF13401.1 EWM26173.1 - 1.2e-05 25.4 0.1 0.00053 20.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EWM26173.1 - 2.1e-05 24.5 0.6 9.9e-05 22.3 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 EWM26173.1 - 0.024 14.8 0.1 6.6 6.9 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Daxx PF03344.10 EWM26173.1 - 2.6 6.4 28.8 4.8 5.5 20.0 1.3 1 0 0 1 1 1 0 Daxx Family Ebola_NP PF05505.7 EWM26173.1 - 3.8 5.4 9.9 6.1 4.7 6.9 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein SAPS PF04499.10 EWM26173.1 - 4.9 5.6 5.7 9.3 4.7 3.9 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF605 PF04652.11 EWM26173.1 - 5.6 6.2 10.5 10 5.3 7.3 1.3 1 0 0 1 1 1 0 Vta1 like Sporozoite_P67 PF05642.6 EWM26173.1 - 8 4.1 9.2 18 3.0 6.4 1.6 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SHQ1 PF04925.10 EWM26175.1 - 3.4e-06 26.6 0.0 4.6e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 SHQ1 protein Nop14 PF04147.7 EWM26175.1 - 0.0002 19.4 22.0 0.00021 19.3 15.2 1.1 1 0 0 1 1 1 1 Nop14-like family CENP-T PF15511.1 EWM26175.1 - 0.004 16.4 12.4 0.0043 16.3 8.6 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Daxx PF03344.10 EWM26175.1 - 0.0092 14.5 19.5 0.01 14.3 13.5 1.1 1 0 0 1 1 1 1 Daxx Family CDC45 PF02724.9 EWM26175.1 - 0.016 13.2 16.8 0.018 13.1 11.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.5 EWM26175.1 - 0.024 14.6 7.3 0.032 14.2 5.0 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Utp14 PF04615.8 EWM26175.1 - 0.1 10.7 13.4 0.12 10.5 9.3 1.0 1 0 0 1 1 1 0 Utp14 protein DUF1510 PF07423.6 EWM26175.1 - 0.11 11.8 15.6 0.14 11.4 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SDA1 PF05285.7 EWM26175.1 - 0.14 11.3 23.9 0.16 11.2 16.6 1.1 1 0 0 1 1 1 0 SDA1 Tom37_C PF11801.3 EWM26175.1 - 0.16 11.8 1.0 0.23 11.2 0.7 1.4 1 0 0 1 1 1 0 Tom37 C-terminal domain SGT1 PF07093.6 EWM26175.1 - 0.22 9.8 13.8 0.25 9.6 9.6 1.1 1 0 0 1 1 1 0 SGT1 protein YL1 PF05764.8 EWM26175.1 - 0.35 10.4 22.3 0.43 10.1 15.4 1.1 1 0 0 1 1 1 0 YL1 nuclear protein WBS_methylT PF12589.3 EWM26175.1 - 0.51 10.8 5.4 1.2 9.6 3.8 1.7 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome Mpp10 PF04006.7 EWM26175.1 - 0.59 8.4 19.8 0.64 8.3 13.7 1.0 1 0 0 1 1 1 0 Mpp10 protein DUF2457 PF10446.4 EWM26175.1 - 0.71 8.5 41.4 0.99 8.0 28.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDV3 PF15359.1 EWM26175.1 - 0.86 9.6 16.5 2.6e+03 -1.6 11.5 2.3 1 1 0 1 1 1 0 Carnitine deficiency-associated protein 3 NOA36 PF06524.7 EWM26175.1 - 1.7 7.8 23.9 2.2 7.4 16.6 1.2 1 0 0 1 1 1 0 NOA36 protein Herpes_LMP1 PF05297.6 EWM26175.1 - 2.5 6.9 11.2 2.7 6.8 7.8 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) SAPS PF04499.10 EWM26175.1 - 2.6 6.5 4.9 2.9 6.4 3.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF506 PF04720.7 EWM26175.1 - 2.7 7.5 5.8 4.1 6.9 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF506) BUD22 PF09073.5 EWM26175.1 - 3 6.8 20.9 3.6 6.5 14.5 1.1 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.6 EWM26175.1 - 3.7 5.5 16.4 4.6 5.2 11.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Cwf_Cwc_15 PF04889.7 EWM26175.1 - 3.9 7.1 22.5 7.1 6.2 15.6 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CobT PF06213.7 EWM26175.1 - 5.4 6.0 28.2 7.2 5.6 19.5 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT polyprenyl_synt PF00348.12 EWM26176.1 - 3.7e-53 180.0 0.6 6.1e-53 179.3 0.4 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 EWM26176.1 - 0.00017 21.1 0.2 0.00033 20.1 0.1 1.4 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 zf-RING_6 PF14835.1 EWM26177.1 - 8.4e-11 41.4 3.2 1.8e-10 40.4 2.2 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.1 EWM26177.1 - 4.3e-07 29.8 12.3 1.3e-06 28.2 8.5 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EWM26177.1 - 3e-06 26.9 10.8 6.8e-06 25.8 7.5 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EWM26177.1 - 4.2e-06 26.3 12.7 9.9e-06 25.1 8.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.10 EWM26177.1 - 7.7e-06 25.7 0.0 2.7e-05 24.0 0.0 2.0 1 0 0 1 1 1 1 U-box domain zf-C3HC4_3 PF13920.1 EWM26177.1 - 9.8e-06 25.1 10.5 2.5e-05 23.8 7.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EWM26177.1 - 4e-05 23.3 12.5 0.00017 21.3 8.6 2.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EWM26177.1 - 0.00021 20.9 12.8 0.00052 19.6 8.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EWM26177.1 - 0.0015 18.2 7.6 0.0037 16.9 5.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.1 EWM26177.1 - 0.046 13.2 7.7 0.12 11.9 5.3 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 EWM26177.1 - 0.16 11.5 7.8 0.45 10.1 5.4 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain CRAL_TRIO PF00650.15 EWM26178.1 - 1e-27 96.5 0.0 1.5e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain Amino_oxidase PF01593.19 EWM26179.1 - 9.4e-30 104.0 1.1 5.2e-21 75.2 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EWM26179.1 - 4.8e-15 55.3 0.1 1.8e-14 53.5 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EWM26179.1 - 1.6e-07 30.5 4.8 3.2e-07 29.5 3.3 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EWM26179.1 - 2.7e-06 26.5 0.6 7.8e-06 25.0 0.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EWM26179.1 - 5.1e-06 25.2 2.5 7.6e-06 24.6 1.7 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 EWM26179.1 - 1.7e-05 25.0 1.4 3.6e-05 24.0 1.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EWM26179.1 - 2.2e-05 24.4 1.2 4.7e-05 23.3 0.8 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EWM26179.1 - 4.5e-05 23.5 0.2 8.7e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EWM26179.1 - 9e-05 21.6 1.8 0.00014 21.0 1.2 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EWM26179.1 - 0.0001 21.4 0.7 0.00017 20.7 0.5 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EWM26179.1 - 0.00088 18.4 4.8 0.0015 17.6 3.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EWM26179.1 - 0.0082 15.7 0.5 0.015 14.8 0.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 EWM26179.1 - 0.011 14.6 2.8 0.017 14.0 2.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EWM26179.1 - 0.03 13.2 1.1 0.08 11.8 0.9 1.7 1 1 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 EWM26179.1 - 0.036 13.8 0.4 0.12 12.1 0.1 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 EWM26179.1 - 0.038 13.3 0.8 0.062 12.6 0.5 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FMO-like PF00743.14 EWM26179.1 - 0.046 11.9 0.1 0.064 11.4 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like TrkA_N PF02254.13 EWM26179.1 - 0.047 13.6 0.3 0.13 12.2 0.2 1.8 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.1 EWM26179.1 - 0.054 13.7 0.2 0.15 12.3 0.1 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 EWM26179.1 - 0.12 12.0 2.6 0.25 10.9 1.8 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EWM26179.1 - 0.24 11.4 0.5 0.5 10.4 0.4 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.9 EWM26179.1 - 1.7 7.2 3.5 2.5 6.6 2.4 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Ribosomal_L6 PF00347.18 EWM26180.1 - 1.2e-28 99.4 0.9 4e-13 49.6 0.1 3.0 2 1 0 2 2 2 2 Ribosomal protein L6 ABC_membrane PF00664.18 EWM26181.1 - 4.4e-53 180.4 14.2 7.9e-34 117.3 4.9 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EWM26181.1 - 1.3e-48 164.8 0.0 3e-28 98.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EWM26181.1 - 7.4e-08 31.8 0.8 0.31 10.2 0.2 4.0 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EWM26181.1 - 2.6e-07 30.0 0.1 0.017 14.6 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EWM26181.1 - 3.5e-06 27.1 0.1 0.017 15.1 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 EWM26181.1 - 2e-05 24.7 0.0 1.3 8.9 0.0 4.1 4 0 0 4 4 4 1 AAA domain MMR_HSR1 PF01926.18 EWM26181.1 - 2.3e-05 24.3 0.1 0.29 11.0 0.0 3.6 4 0 0 4 4 3 1 50S ribosome-binding GTPase AAA_23 PF13476.1 EWM26181.1 - 4.7e-05 23.8 0.6 0.31 11.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EWM26181.1 - 7e-05 22.3 0.3 0.88 8.9 0.0 3.5 4 0 0 4 4 4 2 AAA domain Miro PF08477.8 EWM26181.1 - 7.4e-05 23.2 0.2 0.56 10.7 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein NACHT PF05729.7 EWM26181.1 - 0.00012 21.8 0.4 0.065 12.8 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_17 PF13207.1 EWM26181.1 - 0.00014 22.6 0.3 0.38 11.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EWM26181.1 - 0.00015 20.8 0.0 0.29 9.9 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF87 PF01935.12 EWM26181.1 - 0.00015 21.7 3.5 0.054 13.2 0.5 2.4 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_19 PF13245.1 EWM26181.1 - 0.00052 19.7 0.7 0.3 10.8 0.0 3.7 3 0 0 3 3 3 1 Part of AAA domain SbcCD_C PF13558.1 EWM26181.1 - 0.00065 19.5 0.0 0.039 13.8 0.0 2.8 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.17 EWM26181.1 - 0.00077 18.4 0.6 0.31 9.8 0.0 2.2 2 0 0 2 2 2 2 NB-ARC domain cobW PF02492.14 EWM26181.1 - 0.00096 18.6 1.4 0.97 8.8 0.1 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EWM26181.1 - 0.0014 18.8 0.7 1.1 9.4 0.1 3.2 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 EWM26181.1 - 0.002 17.8 0.5 2 8.1 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EWM26181.1 - 0.0026 18.0 0.5 3.4 7.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EWM26181.1 - 0.0027 17.3 0.0 2.4 7.6 0.0 3.0 2 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EWM26181.1 - 0.0039 16.9 0.1 0.23 11.1 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase NTPase_1 PF03266.10 EWM26181.1 - 0.012 15.3 0.2 0.76 9.4 0.0 2.6 2 0 0 2 2 2 0 NTPase ArgK PF03308.11 EWM26181.1 - 0.013 14.2 0.3 0.68 8.6 0.0 2.2 2 0 0 2 2 2 0 ArgK protein AAA_10 PF12846.2 EWM26181.1 - 0.014 14.8 3.1 2.9 7.2 0.1 3.3 2 1 0 3 3 3 0 AAA-like domain DUF258 PF03193.11 EWM26181.1 - 0.016 14.3 0.0 5.7 6.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 EWM26181.1 - 0.019 14.8 0.1 6.1 6.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 EWM26181.1 - 0.03 13.3 0.0 0.96 8.3 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain FtsK_SpoIIIE PF01580.13 EWM26181.1 - 0.034 13.5 0.2 6.3 6.2 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family UPF0079 PF02367.12 EWM26181.1 - 0.042 13.4 0.1 9.9 5.8 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ATP-synt_ab PF00006.20 EWM26181.1 - 0.045 13.2 0.1 1.9 7.9 0.0 2.5 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.18 EWM26181.1 - 0.07 12.9 2.6 0.63 9.8 0.1 2.8 3 0 0 3 3 3 0 Dynamin family AAA_24 PF13479.1 EWM26181.1 - 0.1 12.1 1.8 2.5 7.6 0.1 2.7 3 0 0 3 3 3 0 AAA domain GTP_EFTU PF00009.22 EWM26181.1 - 0.13 11.7 0.0 5 6.5 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain TrwB_AAD_bind PF10412.4 EWM26181.1 - 0.14 10.7 0.2 8.9 4.8 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Pox_A32 PF04665.7 EWM26181.1 - 0.16 11.2 0.3 1.7 7.8 0.0 2.1 2 0 0 2 2 2 0 Poxvirus A32 protein CoaE PF01121.15 EWM26181.1 - 0.28 10.5 2.1 6.4 6.1 0.2 2.4 2 0 0 2 2 2 0 Dephospho-CoA kinase ATP_bind_1 PF03029.12 EWM26181.1 - 0.28 10.6 0.3 27 4.2 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 EWM26181.1 - 0.32 11.1 0.1 34 4.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_15 PF13175.1 EWM26181.1 - 1.7 7.6 0.1 16 4.4 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain Abhydrolase_6 PF12697.2 EWM26182.1 - 8.2e-35 120.7 0.3 1.2e-34 120.1 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM26182.1 - 5.6e-12 45.6 0.0 3.9e-11 42.8 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EWM26182.1 - 5.4e-11 42.4 0.0 2.6e-10 40.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EWM26182.1 - 0.00032 20.4 0.0 0.0006 19.6 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 EWM26182.1 - 0.0045 16.4 0.0 5.5 6.3 0.0 3.0 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase DLH PF01738.13 EWM26182.1 - 0.012 14.8 0.0 0.78 8.9 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydro_lipase PF04083.11 EWM26182.1 - 0.064 12.6 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region PK PF00224.16 EWM26183.1 - 7.6e-110 366.7 0.2 9.6e-110 366.4 0.2 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EWM26183.1 - 3.8e-33 113.5 0.2 1.1e-32 112.0 0.1 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain MAS20 PF02064.10 EWM26183.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 MAS20 protein import receptor Peptidase_M1 PF01433.15 EWM26184.1 - 0.056 12.5 0.0 0.066 12.2 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M1 VacA2 PF03077.9 EWM26184.1 - 0.12 11.9 0.4 0.23 11.0 0.0 1.6 2 0 0 2 2 2 0 Putative vacuolating cytotoxin Thioredoxin PF00085.15 EWM26185.1 - 3.3e-08 33.1 0.0 8.9e-08 31.7 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 EWM26185.1 - 0.062 12.0 5.7 0.3 9.7 4.0 1.9 1 1 0 1 1 1 0 Phosducin DIE2_ALG10 PF04922.7 EWM26186.1 - 3e-78 263.5 5.8 5.1e-52 177.1 0.0 2.9 2 1 0 2 2 2 2 DIE2/ALG10 family Rieske PF00355.21 EWM26188.1 - 2.1e-18 65.6 0.0 4.3e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.7 EWM26188.1 - 5.3e-17 61.5 0.0 1.3e-16 60.2 0.0 1.7 1 0 0 1 1 1 1 Pheophorbide a oxygenase Rieske_2 PF13806.1 EWM26188.1 - 0.0091 15.6 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain RPEL PF02755.10 EWM26189.1 - 4e-05 22.7 0.0 0.012 14.8 0.0 3.1 3 0 0 3 3 3 2 RPEL repeat SNF2_N PF00176.18 EWM26190.1 - 8.8e-47 159.3 0.0 1.3e-46 158.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EWM26190.1 - 0.019 14.8 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EWM26190.1 - 1.8 8.2 13.7 3.9 7.2 9.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 EWM26190.1 - 2.5 7.7 9.5 5.4 6.6 6.6 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.1 EWM26190.1 - 5.6 6.7 15.4 13 5.6 10.7 1.7 1 0 0 1 1 1 0 zinc-RING finger domain LRR_9 PF14580.1 EWM26191.1 - 1.2e-60 204.0 0.9 1.9e-60 203.4 0.6 1.3 1 0 0 1 1 1 1 Leucine-rich repeat SAP PF02037.22 EWM26191.1 - 2.9e-13 48.9 0.4 2.9e-13 48.9 0.3 1.9 2 0 0 2 2 2 1 SAP domain LRR_4 PF12799.2 EWM26191.1 - 5e-13 48.3 3.4 1.4e-05 24.5 0.3 3.2 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EWM26191.1 - 5.3e-08 32.4 6.8 4.2e-06 26.4 2.9 3.5 3 1 1 4 4 4 2 Leucine rich repeat LETM1 PF07766.8 EWM26191.1 - 0.015 14.3 1.0 0.023 13.7 0.1 1.6 2 0 0 2 2 2 0 LETM1-like protein LRR_1 PF00560.28 EWM26191.1 - 0.77 10.0 7.8 60 4.2 0.1 5.0 5 0 0 5 5 5 0 Leucine Rich Repeat DUF4164 PF13747.1 EWM26191.1 - 8.6 6.5 9.5 9 6.5 1.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) DEAD PF00270.24 EWM26192.1 - 7.2e-44 149.2 0.0 2.2e-43 147.6 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EWM26192.1 - 8.1e-22 76.8 0.0 1.5e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SPRY PF00622.23 EWM26192.1 - 2.1e-19 69.8 0.3 4.5e-19 68.7 0.2 1.6 1 0 0 1 1 1 1 SPRY domain Gal4_dimer PF03902.8 EWM26194.1 - 0.64 9.9 6.2 3.5 7.6 0.0 4.1 4 0 0 4 4 4 0 Gal4-like dimerisation domain XAP5 PF04921.9 EWM26195.1 - 5.4e-84 281.5 8.2 2.3e-83 279.4 0.0 2.0 2 0 0 2 2 2 2 XAP5, circadian clock regulator FLO_LFY PF01698.11 EWM26195.1 - 6.4 5.5 14.3 8.5 5.1 9.9 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein ERAP1_C PF11838.3 EWM26196.1 - 0.0066 15.7 0.0 0.0091 15.2 0.0 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain WD40 PF00400.27 EWM26197.1 - 2.4e-85 277.6 12.7 1.3e-10 40.7 0.1 11.9 11 1 0 11 11 11 10 WD domain, G-beta repeat Utp13 PF08625.6 EWM26197.1 - 3.7e-31 107.6 0.0 5.5e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 EWM26197.1 - 3.5e-06 25.4 3.2 2.1 6.3 0.0 5.2 3 2 2 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EWM26197.1 - 0.00068 18.5 0.0 16 4.1 0.0 5.0 3 2 1 4 4 4 2 Nup133 N terminal like DDA1 PF10172.4 EWM26197.1 - 0.25 11.2 0.0 0.61 9.9 0.0 1.6 1 0 0 1 1 1 0 Det1 complexing ubiquitin ligase HEAT PF02985.17 EWM26198.1 - 0.032 14.2 0.0 0.095 12.8 0.0 1.8 1 0 0 1 1 1 0 HEAT repeat FGGY_N PF00370.16 EWM26199.1 - 2.1e-51 174.6 0.0 2.5e-51 174.3 0.0 1.0 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain EMP24_GP25L PF01105.19 EWM26200.1 - 2.2e-20 73.1 0.0 2.7e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PAS_10 PF13596.1 EWM26200.1 - 0.1 12.8 0.2 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 PAS domain Glyco_transf_34 PF05637.7 EWM26201.1 - 2.7e-10 40.1 0.0 9.8e-06 25.2 0.0 2.4 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family Gly_transf_sug PF04488.10 EWM26201.1 - 1.5e-07 31.7 0.0 1.1e-05 25.7 0.0 2.5 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif DUF273 PF03314.9 EWM26201.1 - 0.035 13.4 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF273 Sigma70_r3 PF04539.11 EWM26203.1 - 2.4e-07 30.5 0.3 0.0042 16.9 0.0 2.8 2 0 0 2 2 2 2 Sigma-70 region 3 Sigma70_r2 PF04542.9 EWM26203.1 - 6.4e-06 25.6 0.3 1.6e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4 PF04545.11 EWM26203.1 - 8.9e-06 24.9 0.7 0.0028 16.9 0.0 2.8 2 0 0 2 2 2 2 Sigma-70, region 4 Sigma70_r4_2 PF08281.7 EWM26203.1 - 0.00023 20.5 0.3 0.17 11.3 0.0 2.6 2 0 0 2 2 2 2 Sigma-70, region 4 Ribosomal_L14 PF00238.14 EWM26204.1 - 4e-10 39.5 0.0 6e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e DUF1604 PF07713.8 EWM26205.1 - 2.6e-32 110.4 1.7 2.6e-32 110.4 1.2 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.18 EWM26205.1 - 0.00079 19.1 4.3 0.003 17.3 3.0 2.0 1 0 0 1 1 1 1 G-patch domain Mito_carr PF00153.22 EWM26206.1 - 1e-67 223.8 1.8 1.3e-23 82.5 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 EWM26206.1 - 4.9e-17 61.8 3.7 2.5e-07 30.7 1.3 4.7 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 EWM26206.1 - 2.7e-15 54.4 2.2 0.0012 18.0 0.0 5.2 5 0 0 5 5 5 3 EF hand cNMP_binding PF00027.24 EWM26206.1 - 3.3e-15 55.6 0.2 3.5e-14 52.3 0.1 2.3 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain EF-hand_6 PF13405.1 EWM26206.1 - 1e-14 52.9 2.6 0.002 17.8 0.0 4.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 EWM26206.1 - 6.2e-10 38.5 0.3 4.2e-05 23.0 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 EWM26206.1 - 3.8e-08 32.2 4.0 0.0015 17.8 0.0 4.2 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.1 EWM26206.1 - 0.046 13.6 2.8 11 6.0 0.0 3.9 3 1 1 4 4 4 0 EF-hand domain DUF150 PF02576.12 EWM26207.1 - 5.1e-12 45.5 0.0 7.9e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised BCR, YhbC family COG0779 TB2_DP1_HVA22 PF03134.14 EWM26208.1 - 7.2e-16 57.7 1.7 1.1e-15 57.1 1.2 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Spore_YpjB PF09577.5 EWM26208.1 - 0.13 11.8 0.0 2 7.9 0.0 2.0 2 0 0 2 2 2 0 Sporulation protein YpjB (SpoYpjB) Pkinase PF00069.20 EWM26209.1 - 1.2e-16 60.7 0.0 1.6e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 EWM26209.1 - 0.00012 21.1 0.0 0.00062 18.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_Tyr PF07714.12 EWM26209.1 - 0.00024 20.2 0.0 0.00049 19.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EWM26209.1 - 0.15 11.1 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TP6A_N PF04406.9 EWM26210.1 - 1.7e-09 37.1 0.0 3e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Type IIB DNA topoisomerase HIRAN PF08797.6 EWM26210.1 - 0.049 13.5 0.0 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 HIRAN domain DnaJ PF00226.26 EWM26211.1 - 3.3e-14 52.3 0.1 7.3e-14 51.2 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain RAP1 PF07218.6 EWM26211.1 - 0.15 10.1 2.9 0.17 9.9 2.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF883 PF05957.8 EWM26211.1 - 0.47 10.8 8.1 0.21 12.0 2.9 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF3735 PF12537.3 EWM26211.1 - 0.98 9.5 3.3 7.4 6.6 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3735) DUF3347 PF11827.3 EWM26211.1 - 7.3 6.5 8.4 3.8 7.4 2.2 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3347) Josephin PF02099.12 EWM26212.1 - 1.6e-07 31.0 0.0 1.2e-05 25.0 0.0 2.6 1 1 0 1 1 1 1 Josephin UcrQ PF02939.11 EWM26213.1 - 0.02 14.6 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 UcrQ family PAN_2 PF08276.6 EWM26213.1 - 0.094 12.5 0.4 0.17 11.7 0.3 1.4 1 0 0 1 1 1 0 PAN-like domain TPR_19 PF14559.1 EWM26214.1 - 2.3e-15 56.6 4.8 0.00085 19.6 0.1 7.7 5 1 3 8 8 8 5 Tetratricopeptide repeat Apc3 PF12895.2 EWM26214.1 - 8.8e-11 41.7 17.1 0.0039 17.3 1.2 5.9 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EWM26214.1 - 1.2e-10 41.7 19.5 0.00086 19.9 0.2 6.7 8 1 0 8 8 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 EWM26214.1 - 1.8e-09 37.1 16.8 0.011 15.3 0.5 6.5 5 2 0 5 5 5 3 TPR repeat TPR_2 PF07719.12 EWM26214.1 - 4.5e-09 35.5 28.5 0.062 13.2 0.2 7.8 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_1 PF00515.23 EWM26214.1 - 8.1e-06 25.2 15.6 0.12 12.0 0.6 6.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 EWM26214.1 - 6.6e-05 22.6 24.1 0.00095 18.9 0.5 5.8 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 EWM26214.1 - 0.00031 21.1 24.3 0.94 10.2 0.1 8.3 8 2 1 10 10 8 2 Tetratricopeptide repeat TPR_6 PF13174.1 EWM26214.1 - 0.00068 19.9 14.3 2.9 8.5 0.1 7.1 7 0 0 7 7 6 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EWM26214.1 - 0.0029 17.4 6.4 0.13 12.1 0.1 4.0 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.1 EWM26214.1 - 0.012 15.3 8.0 0.4 10.5 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Coatomer_E PF04733.9 EWM26214.1 - 0.084 12.0 1.3 27 3.8 0.0 4.0 4 1 1 5 5 5 0 Coatomer epsilon subunit TPR_4 PF07721.9 EWM26214.1 - 0.097 13.1 5.7 4.4 8.0 0.0 4.8 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EWM26214.1 - 0.26 11.2 22.0 1.6 8.7 0.2 6.7 4 2 3 8 8 8 0 Tetratricopeptide repeat TPR_3 PF07720.7 EWM26214.1 - 1.3 8.9 13.1 11 5.9 0.2 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF974 PF06159.8 EWM26215.1 - 5.7e-32 111.1 0.0 8.8e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Trs65 PF12735.2 EWM26215.1 - 6.5e-08 32.2 0.2 0.00083 18.7 0.0 2.4 2 0 0 2 2 2 2 TRAPP trafficking subunit Trs65 Gryzun-like PF12742.2 EWM26215.1 - 0.16 11.7 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking MgtC PF02308.11 EWM26216.1 - 0.013 15.2 0.2 0.027 14.3 0.1 1.4 1 0 0 1 1 1 0 MgtC family Cu-oxidase_3 PF07732.10 EWM26216.1 - 0.028 14.1 0.0 0.078 12.7 0.0 1.7 2 0 0 2 2 2 0 Multicopper oxidase WD40 PF00400.27 EWM26217.1 - 5.5e-64 209.9 11.0 4.2e-12 45.4 0.0 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EWM26217.1 - 7.9e-06 24.2 1.0 0.036 12.1 0.0 4.1 1 1 3 4 4 4 2 Nucleoporin Nup120/160 eIF2A PF08662.6 EWM26217.1 - 9.1e-05 22.2 0.0 0.18 11.5 0.0 2.7 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EWM26217.1 - 0.00056 18.7 0.1 1.2 7.7 0.1 3.9 2 1 1 3 3 3 2 Nup133 N terminal like Coatomer_WDAD PF04053.9 EWM26217.1 - 0.0027 16.5 0.0 0.14 10.8 0.0 2.7 2 1 0 3 3 3 1 Coatomer WD associated region Toxin_28 PF08115.6 EWM26217.1 - 0.64 9.7 0.0 0.64 9.7 0.0 2.7 3 0 0 3 3 3 0 SFI toxin family Acetyltransf_1 PF00583.19 EWM26218.1 - 0.15 12.1 0.2 1.6 8.7 0.1 2.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family PfkB PF00294.19 EWM26219.1 - 4.6e-39 134.3 0.0 2.2e-32 112.3 0.0 2.1 1 1 1 2 2 2 2 pfkB family carbohydrate kinase Pro_isomerase PF00160.16 EWM26220.1 - 7.4e-23 81.4 0.0 1.1e-22 80.9 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Tmemb_14 PF03647.8 EWM26221.1 - 5.3e-18 65.2 11.3 6.9e-18 64.8 7.8 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C RnfC_N PF13375.1 EWM26221.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Chromate_transp PF02417.10 EWM26221.1 - 0.26 10.8 4.8 0.29 10.6 3.3 1.0 1 0 0 1 1 1 0 Chromate transporter MORN PF02493.15 EWM26222.1 - 1.1e-71 232.5 143.7 8.7e-06 25.1 1.5 24.5 26 0 0 26 26 26 20 MORN repeat Avl9 PF09794.4 EWM26222.1 - 3e-21 75.3 0.1 1.9e-15 56.2 0.0 3.2 2 1 0 2 2 2 2 Transport protein Avl9 DENN PF02141.16 EWM26222.1 - 3.2e-05 23.7 0.3 7.3e-05 22.5 0.2 1.6 1 1 0 1 1 1 1 DENN (AEX-3) domain SPA PF08616.5 EWM26222.1 - 0.001 18.7 0.0 0.032 13.9 0.0 2.3 1 1 0 1 1 1 1 Stabilization of polarity axis ICL PF00463.16 EWM26223.1 - 1.7e-226 752.5 0.0 2e-226 752.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EWM26223.1 - 8e-13 48.1 0.1 8.5e-12 44.8 0.0 2.3 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Glyco_hydro_3 PF00933.16 EWM26224.1 - 3.1e-62 210.2 0.0 5.5e-62 209.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EWM26224.1 - 3.1e-48 164.2 0.3 4.4e-45 153.9 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EWM26224.1 - 0.00095 19.0 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain SMC_N PF02463.14 EWM26225.1 - 2.7e-66 222.9 0.0 7.5e-66 221.5 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EWM26225.1 - 5.1e-23 81.3 0.2 2.6e-22 79.0 0.1 2.4 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EWM26225.1 - 2.2e-12 47.5 1.9 1.4e-05 25.2 0.2 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EWM26225.1 - 4.5e-06 27.1 30.0 4.5e-06 27.1 20.8 6.4 2 2 0 2 2 2 1 AAA domain GAS PF13851.1 EWM26225.1 - 0.00031 20.0 3.9 0.00031 20.0 2.7 7.1 4 2 2 6 6 6 3 Growth-arrest specific micro-tubule binding AAA_29 PF13555.1 EWM26225.1 - 0.00057 19.3 0.0 0.002 17.6 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EWM26225.1 - 0.053 13.8 0.1 0.053 13.8 0.0 5.3 4 2 0 5 5 5 0 ABC transporter AAA_17 PF13207.1 EWM26225.1 - 0.15 12.8 5.4 2.5 8.9 0.0 3.9 4 1 0 4 4 4 0 AAA domain AAA_15 PF13175.1 EWM26225.1 - 6.8 5.6 28.5 0.011 14.8 7.3 3.8 2 2 0 2 2 2 0 AAA ATPase domain Got1 PF04178.7 EWM26226.1 - 2.3e-27 95.4 14.9 6.4e-27 93.9 10.5 1.6 1 1 1 2 2 2 2 Got1/Sft2-like family Acyl_transf_3 PF01757.17 EWM26226.1 - 0.025 13.3 10.1 0.28 9.9 7.0 1.9 1 1 0 1 1 1 0 Acyltransferase family MMPL PF03176.10 EWM26226.1 - 0.078 11.6 1.0 0.12 11.1 0.7 1.2 1 0 0 1 1 1 0 MMPL family DUF4579 PF15158.1 EWM26226.1 - 0.22 11.0 1.9 1.2 8.6 1.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4579) DUF2614 PF11023.3 EWM26226.1 - 1.3 8.8 9.3 0.1 12.3 1.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2614) DUF4149 PF13664.1 EWM26226.1 - 5.9 7.0 11.3 14 5.8 3.7 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4149) Kinesin PF00225.18 EWM26228.1 - 2.1e-97 325.8 0.0 1.2e-96 323.3 0.0 2.3 2 0 0 2 2 2 1 Kinesin motor domain Reo_sigmaC PF04582.7 EWM26228.1 - 3.8 6.5 80.7 1.6 7.8 0.2 12.2 4 2 11 16 16 16 0 Reovirus sigma C capsid protein ubiquitin PF00240.18 EWM26229.1 - 4.4e-35 118.8 0.9 6.7e-35 118.3 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S30 PF04758.9 EWM26229.1 - 5.2e-27 93.3 6.5 1e-26 92.4 4.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S30 Rad60-SLD PF11976.3 EWM26229.1 - 1.3e-20 72.7 0.7 2.2e-20 72.1 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EWM26229.1 - 2.1e-06 27.8 0.1 6.4e-06 26.3 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EWM26229.1 - 1.3e-05 24.9 0.1 1.7e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Telomere stability and silencing DUF2407 PF10302.4 EWM26229.1 - 0.00075 19.6 0.3 0.0011 19.0 0.2 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EWM26229.1 - 0.0038 17.0 0.2 0.015 15.2 0.1 2.1 1 1 1 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like TUG-UBL1 PF11470.3 EWM26229.1 - 0.046 13.6 0.1 0.085 12.7 0.0 1.5 1 0 0 1 1 1 0 GLUT4 regulating protein TUG MutS_V PF00488.16 EWM26231.1 - 4.9e-37 127.5 0.0 8.5e-37 126.8 0.0 1.4 1 0 0 1 1 1 1 MutS domain V Smr PF01713.16 EWM26231.1 - 8.3e-12 45.1 0.1 3.1e-11 43.2 0.1 2.1 2 0 0 2 2 2 1 Smr domain AAA_21 PF13304.1 EWM26231.1 - 0.0002 21.4 0.0 0.046 13.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain MutS_III PF05192.13 EWM26231.1 - 0.00024 20.9 2.3 0.0003 20.6 0.1 2.0 2 0 0 2 2 2 1 MutS domain III OmpH PF03938.9 EWM26231.1 - 0.085 12.7 7.5 0.14 12.0 4.7 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) AAA_13 PF13166.1 EWM26231.1 - 1 7.7 4.0 1.6 7.1 2.8 1.2 1 0 0 1 1 1 0 AAA domain Erp_C PF06780.6 EWM26231.1 - 1.3 8.8 6.5 1.7 8.4 3.3 2.1 1 1 0 1 1 1 0 Erp protein C-terminus APG6 PF04111.7 EWM26231.1 - 1.7 7.6 5.2 3.6 6.5 3.6 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 KTI12 PF08433.5 EWM26232.1 - 1.7e-18 66.8 0.0 4.8e-18 65.3 0.0 1.7 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EWM26232.1 - 1e-11 44.8 0.0 3.2e-10 40.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EWM26232.1 - 0.018 14.1 0.0 0.55 9.2 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin 6PF2K PF01591.13 EWM26232.1 - 0.079 12.0 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Vps51 PF08700.6 EWM26233.1 - 0.0044 16.8 5.9 0.0095 15.7 4.1 1.6 1 0 0 1 1 1 1 Vps51/Vps67 DUF4094 PF13334.1 EWM26233.1 - 0.032 14.6 12.2 0.28 11.6 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) DUF1993 PF09351.5 EWM26233.1 - 0.11 12.3 1.5 0.24 11.3 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) DUF3138 PF11336.3 EWM26233.1 - 0.21 9.7 0.5 0.36 8.9 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) DUF2730 PF10805.3 EWM26233.1 - 0.31 10.7 5.9 0.38 10.5 3.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) V_ATPase_I PF01496.14 EWM26233.1 - 0.32 8.7 8.7 0.45 8.3 6.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PRP1_N PF06424.7 EWM26233.1 - 0.71 10.1 8.5 1.5 9.1 5.9 1.5 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal DUF3573 PF12097.3 EWM26233.1 - 0.72 8.3 2.6 1.1 7.7 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Ax_dynein_light PF10211.4 EWM26233.1 - 0.9 9.3 15.4 0.76 9.5 9.3 1.8 1 1 1 2 2 2 0 Axonemal dynein light chain DUF1664 PF07889.7 EWM26233.1 - 1.4 8.6 7.6 1.8 8.3 4.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) IncA PF04156.9 EWM26233.1 - 4.4 6.8 19.7 2.9 7.4 11.4 2.2 2 1 0 2 2 2 0 IncA protein Mnd1 PF03962.10 EWM26233.1 - 5 6.7 18.5 1.5 8.4 9.6 2.2 2 1 0 2 2 2 0 Mnd1 family DUF342 PF03961.8 EWM26233.1 - 9.5 4.4 15.5 20 3.4 10.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Arm PF00514.18 EWM26234.1 - 5.9e-92 298.7 15.0 1.4e-13 50.1 0.0 9.5 10 0 0 10 10 10 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EWM26234.1 - 1.2e-28 99.1 0.5 8.1e-11 42.0 0.0 6.0 2 1 3 6 6 6 5 HEAT repeats HEAT_EZ PF13513.1 EWM26234.1 - 8.6e-24 83.3 4.3 3.9e-10 39.8 0.0 6.3 4 2 4 8 8 7 5 HEAT-like repeat IBB PF01749.15 EWM26234.1 - 7.1e-19 67.7 1.2 1.4e-18 66.8 0.9 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 EWM26234.1 - 3e-16 57.9 2.6 2e-06 27.4 0.0 7.4 8 0 0 8 8 8 3 HEAT repeat Arm_2 PF04826.8 EWM26234.1 - 8.1e-09 34.9 0.0 0.0083 15.2 0.0 3.7 1 1 2 4 4 4 2 Armadillo-like Adaptin_N PF01602.15 EWM26234.1 - 6.6e-07 28.0 0.0 0.6 8.3 0.0 3.8 1 1 2 3 3 3 3 Adaptin N terminal region V-ATPase_H_C PF11698.3 EWM26234.1 - 6.8e-07 29.2 0.0 0.64 9.9 0.0 4.5 3 1 2 5 5 5 2 V-ATPase subunit H HEAT_PBS PF03130.11 EWM26234.1 - 1.1e-05 25.3 0.8 0.29 11.7 0.1 5.3 5 0 0 5 5 4 1 PBS lyase HEAT-like repeat Neurochondrin PF05536.6 EWM26234.1 - 0.0095 14.2 0.1 2.5 6.2 0.0 3.0 1 1 3 4 4 4 1 Neurochondrin U79_P34 PF03064.11 EWM26234.1 - 0.015 14.8 0.6 0.024 14.1 0.4 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Proteasom_PSMB PF10508.4 EWM26234.1 - 0.019 13.2 0.1 2.1 6.5 0.0 2.9 2 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit DUF2780 PF11075.3 EWM26234.1 - 0.067 13.2 0.3 2.7 8.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function VcgC/VcgE (DUF2780) Aconitase_B_N PF11791.3 EWM26234.1 - 0.071 12.9 0.4 13 5.5 0.0 3.9 3 1 1 4 4 4 0 Aconitate B N-terminal domain WW PF00397.21 EWM26235.1 - 9.9e-10 38.1 7.8 3.1e-09 36.5 5.4 1.9 1 0 0 1 1 1 1 WW domain WW PF00397.21 EWM26236.1 - 9.9e-10 38.1 7.8 3.1e-09 36.5 5.4 1.9 1 0 0 1 1 1 1 WW domain AMP-binding PF00501.23 EWM26237.1 - 6.7e-11 41.2 0.0 1.4e-10 40.1 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme AAA_12 PF13087.1 EWM26238.1 - 3.9e-46 156.9 0.0 6.4e-46 156.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EWM26238.1 - 4.3e-36 124.6 0.5 6.9e-22 78.1 0.1 2.3 1 1 1 2 2 2 2 AAA domain Dna2 PF08696.6 EWM26238.1 - 8.2e-35 120.0 0.0 1.3e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_30 PF13604.1 EWM26238.1 - 4.8e-12 45.8 0.2 1.1e-11 44.6 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EWM26238.1 - 2.2e-07 30.5 3.0 5.3e-06 26.0 0.3 3.0 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 EWM26238.1 - 0.00043 19.7 0.0 0.001 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EWM26238.1 - 0.00088 19.4 0.0 0.0059 16.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EWM26238.1 - 0.0021 17.6 0.1 2 7.8 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 EWM26238.1 - 0.012 15.2 0.0 0.034 13.7 0.0 1.8 1 1 0 1 1 1 0 Helicase UvrD_C_2 PF13538.1 EWM26238.1 - 0.019 15.1 0.0 0.043 13.9 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 EWM26238.1 - 0.02 14.2 0.2 0.051 12.8 0.1 1.7 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain ResIII PF04851.10 EWM26238.1 - 0.036 13.8 0.0 0.1 12.4 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.12 EWM26238.1 - 0.068 12.5 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.4 EWM26238.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 EWM26238.1 - 0.12 11.6 0.0 0.26 10.5 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein SRP54 PF00448.17 EWM26238.1 - 0.18 11.2 0.1 0.85 9.0 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF1997 PF09366.5 EWM26239.1 - 1.6e-14 54.0 0.0 2.1e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1997) Bac_DNA_binding PF00216.16 EWM26240.1 - 1.2e-28 98.9 0.2 1.6e-28 98.5 0.1 1.2 1 0 0 1 1 1 1 Bacterial DNA-binding protein DUF4496 PF14908.1 EWM26240.1 - 0.00078 19.3 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4496) HU-DNA_bdg PF14848.1 EWM26240.1 - 0.0014 18.3 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 DNA-binding domain HALZ PF02183.13 EWM26241.1 - 0.13 11.9 19.0 0.24 11.1 0.4 6.4 6 0 0 6 6 6 0 Homeobox associated leucine zipper Reo_sigmaC PF04582.7 EWM26241.1 - 0.28 10.3 4.2 0.94 8.5 0.4 2.9 3 0 0 3 3 3 0 Reovirus sigma C capsid protein CpeT PF06206.6 EWM26242.1 - 5.6e-08 32.6 0.0 1.6e-05 24.6 0.0 2.5 2 1 0 2 2 2 2 CpeT/CpcT family (DUF1001) HSP33 PF01430.14 EWM26243.1 - 6e-58 196.1 0.0 7.5e-58 195.8 0.0 1.1 1 0 0 1 1 1 1 Hsp33 protein Proteasome PF00227.21 EWM26245.1 - 1.4e-23 83.1 0.0 1.4e-12 47.2 0.0 2.3 2 0 0 2 2 2 2 Proteasome subunit CMS1 PF14617.1 EWM26246.1 - 4.1e-26 91.5 0.1 5.4e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 EWM26246.1 - 0.00048 19.6 0.0 0.00061 19.3 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1180 PF06679.7 EWM26246.1 - 0.048 13.5 0.3 0.085 12.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) RRM_1 PF00076.17 EWM26247.1 - 6.9e-16 57.6 0.1 2e-15 56.1 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM26247.1 - 3.5e-12 46.1 0.1 1e-11 44.6 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM26247.1 - 2.2e-09 37.0 0.2 7.2e-09 35.3 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M24 PF00557.19 EWM26248.1 - 5.9e-54 182.7 0.0 9.2e-54 182.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EWM26248.1 - 9.5e-31 105.9 0.0 1.7e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain UPF0081 PF03652.10 EWM26249.1 - 3.5e-23 82.2 0.0 5.9e-16 58.8 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0081) ATG11 PF10377.4 EWM26250.1 - 2.8e-14 53.1 0.0 1.6e-12 47.4 0.0 2.2 2 0 0 2 2 2 2 Autophagy-related protein 11 WHIM2 PF15613.1 EWM26250.1 - 0.021 14.7 0.0 0.051 13.5 0.0 1.7 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 2 HSCB_C PF07743.8 EWM26251.1 - 8.9e-13 48.5 4.1 8.9e-13 48.5 2.8 2.4 1 1 1 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 EWM26251.1 - 1.4e-09 37.5 0.1 2.4e-09 36.7 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Synaphin PF05835.7 EWM26252.1 - 0.23 11.6 6.2 0.34 11.0 4.3 1.2 1 0 0 1 1 1 0 Synaphin protein DNA_pol_B PF00136.16 EWM26253.1 - 1e-76 258.6 0.0 1.5e-76 258.1 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EWM26253.1 - 3.8e-19 68.7 0.0 5.8e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EWM26253.1 - 3.8e-08 33.1 13.2 7.2e-08 32.3 9.1 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.8 EWM26253.1 - 0.22 10.1 0.0 0.35 9.4 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral Abhydrolase_1 PF00561.15 EWM26254.1 - 2.6e-24 86.0 0.0 1.3e-11 44.4 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EWM26254.1 - 3.5e-12 46.6 3.5 8.2e-12 45.4 2.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EWM26254.1 - 1.7e-05 24.6 0.0 0.00019 21.3 0.0 2.6 3 0 0 3 3 3 1 TAP-like protein Abhydrolase_5 PF12695.2 EWM26254.1 - 0.032 13.9 2.1 0.11 12.2 1.5 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family RVT_3 PF13456.1 EWM26257.1 - 1e-23 82.9 0.9 1.9e-23 82.0 0.6 1.5 1 0 0 1 1 1 1 Reverse transcriptase-like RNase_H PF00075.19 EWM26257.1 - 4.5e-12 46.4 0.0 1.1e-11 45.2 0.0 1.6 2 0 0 2 2 2 1 RNase H Cauli_VI PF01693.11 EWM26257.1 - 3e-10 39.9 0.0 5.4e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin Sulfatase PF00884.18 EWM26258.1 - 3.4e-65 220.2 0.2 4.3e-65 219.9 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 EWM26258.1 - 0.00013 22.2 0.0 0.00029 21.1 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 EWM26258.1 - 0.02 14.2 0.1 0.2 10.9 0.1 2.0 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Mito_carr PF00153.22 EWM26259.1 - 9.7e-72 236.7 3.9 1.8e-25 88.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Got1 PF04178.7 EWM26260.1 - 5.3e-11 42.6 8.1 5.3e-11 42.6 5.6 1.5 2 0 0 2 2 2 1 Got1/Sft2-like family Aminotran_1_2 PF00155.16 EWM26261.1 - 6.2e-46 157.0 0.0 1e-45 156.2 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EWM26261.1 - 6.5e-05 22.1 0.0 0.00012 21.1 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EWM26261.1 - 0.0031 16.6 0.0 0.087 11.9 0.0 2.0 2 0 0 2 2 2 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EWM26261.1 - 0.29 9.3 0.0 3.1 5.9 0.0 2.0 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme RNA_pol_L_2 PF13656.1 EWM26262.1 - 4.7e-25 86.8 0.0 6.3e-25 86.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EWM26262.1 - 2.2e-05 23.4 0.0 3.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF842 PF05811.8 EWM26263.1 - 8.5e-28 96.4 8.1 9.9e-28 96.2 5.6 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) zf-Tim10_DDP PF02953.10 EWM26263.1 - 0.026 13.7 10.3 1.7 8.0 0.7 3.6 1 1 3 4 4 4 0 Tim10/DDP family zinc finger DUF1409 PF07197.7 EWM26263.1 - 0.23 11.5 1.3 1.1 9.4 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1409) Vicilin_N PF04702.7 EWM26263.1 - 0.25 10.9 11.3 1.7 8.2 0.5 2.2 1 1 0 1 1 1 0 Vicilin N terminal region Vanabin-2 PF11437.3 EWM26263.1 - 1.8 8.6 13.6 4.4 7.3 2.6 2.3 1 1 1 2 2 2 0 Vanadium-binding protein 2 Fer4_21 PF14697.1 EWM26263.1 - 2.9 7.8 10.0 2.3 8.1 0.3 3.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Bin3 PF06859.7 EWM26264.1 - 2.6e-07 30.6 0.0 3.8e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_31 PF13847.1 EWM26264.1 - 1.1e-05 25.1 0.0 0.0011 18.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM26264.1 - 6.4e-05 23.4 0.3 0.00018 22.0 0.2 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM26264.1 - 0.0014 19.0 0.0 0.0064 16.9 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM26264.1 - 0.0089 16.3 0.0 0.027 14.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM26264.1 - 0.058 13.8 0.1 0.24 11.9 0.0 2.1 2 1 1 3 3 3 0 Methyltransferase domain DUF1724 PF08350.5 EWM26264.1 - 0.078 12.5 0.1 0.23 11.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1724) DUF4110 PF13422.1 EWM26264.1 - 0.13 12.0 2.3 0.42 10.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) SAGA-Tad1 PF12767.2 EWM26265.1 - 1.4e-13 51.0 0.1 6.1e-12 45.7 0.0 2.9 3 0 0 3 3 3 1 Transcriptional regulator of RNA polII, SAGA, subunit 2OG-FeII_Oxy_2 PF13532.1 EWM26266.1 - 3.4e-29 102.0 0.0 7.9e-27 94.3 0.0 3.0 2 1 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily ABC1 PF03109.11 EWM26267.1 - 1.4e-33 115.3 0.0 2.9e-33 114.3 0.0 1.6 1 0 0 1 1 1 1 ABC1 family WaaY PF06176.6 EWM26267.1 - 0.019 14.1 0.0 0.037 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.18 EWM26267.1 - 0.17 11.5 1.0 2.4 7.8 0.1 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family Amidase PF01425.16 EWM26268.1 - 1.6e-133 445.8 4.2 1.8e-133 445.6 2.9 1.0 1 0 0 1 1 1 1 Amidase PCNA_N PF00705.13 EWM26272.1 - 4.7e-56 187.7 0.8 7.2e-56 187.1 0.5 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 EWM26272.1 - 1.6e-50 170.2 0.0 6.6e-50 168.3 0.0 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 EWM26272.1 - 7.4e-06 25.2 0.0 8.9e-06 24.9 0.0 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 EWM26272.1 - 0.00047 19.1 0.0 0.088 11.7 0.0 2.1 2 0 0 2 2 2 2 Hus1-like protein LSM PF01423.17 EWM26273.1 - 1.5e-15 56.4 0.4 1.9e-15 56.1 0.3 1.1 1 0 0 1 1 1 1 LSM domain CbiG_N PF11760.3 EWM26273.1 - 0.051 13.2 0.0 0.081 12.6 0.0 1.3 1 0 0 1 1 1 0 Cobalamin synthesis G N-terminal Aconitase PF00330.15 EWM26274.1 - 6.6e-69 232.5 0.1 4.8e-43 147.3 0.0 3.1 2 1 1 3 3 3 3 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EWM26274.1 - 6.8e-18 65.0 0.0 1.2e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain PKD_channel PF08016.7 EWM26275.1 - 8.3e-10 37.6 2.9 1.2e-09 37.1 2.0 1.1 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 EWM26275.1 - 0.013 14.7 7.8 0.021 14.0 5.4 1.3 1 0 0 1 1 1 0 Ion transport protein PUF PF00806.14 EWM26276.1 - 0.00042 19.6 0.0 0.81 9.2 0.0 4.7 5 0 0 5 5 5 2 Pumilio-family RNA binding repeat Kinesin PF00225.18 EWM26277.1 - 6.5e-102 340.6 0.0 9.9e-102 340.0 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DIRP PF06584.8 EWM26277.1 - 0.095 12.5 3.2 0.22 11.4 2.2 1.5 1 0 0 1 1 1 0 DIRP DUF1664 PF07889.7 EWM26277.1 - 0.18 11.6 4.1 0.36 10.6 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF641 PF04859.7 EWM26277.1 - 0.18 11.5 8.3 0.085 12.6 2.9 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) HALZ PF02183.13 EWM26277.1 - 0.28 10.9 8.3 0.047 13.4 1.2 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper IncA PF04156.9 EWM26277.1 - 0.85 9.1 15.5 0.057 13.0 6.1 2.1 2 0 0 2 2 2 0 IncA protein APG6 PF04111.7 EWM26277.1 - 2.4 7.1 13.0 1.7 7.5 6.0 2.3 2 1 1 3 3 3 0 Autophagy protein Apg6 Abhydrolase_5 PF12695.2 EWM26279.1 - 1.2e-09 38.0 0.2 1.9e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EWM26279.1 - 1.9e-06 27.2 0.0 4.2e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EWM26279.1 - 1.8e-05 24.4 0.0 3.5e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EWM26279.1 - 0.00073 19.4 5.6 0.00073 19.4 3.9 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Glyco_trans_4_4 PF13579.1 EWM26279.1 - 0.024 14.7 2.4 0.066 13.3 1.7 1.9 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Abhydrolase_2 PF02230.11 EWM26279.1 - 0.04 13.3 0.5 1.5 8.2 0.0 3.2 3 1 1 4 4 4 0 Phospholipase/Carboxylesterase zf-CCHC_3 PF13917.1 EWM26280.1 - 1.7e-08 34.0 1.1 3e-08 33.2 0.3 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.18 EWM26280.1 - 0.011 15.6 3.4 0.018 14.9 2.4 1.4 1 0 0 1 1 1 0 Zinc knuckle SR-25 PF10500.4 EWM26280.1 - 4.1 6.8 40.4 8.4 5.8 28.0 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Nefa_Nip30_N PF10187.4 EWM26281.1 - 3.3e-13 49.6 13.1 3.3e-13 49.6 9.0 2.2 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 AFG1_ATPase PF03969.11 EWM26281.1 - 0.066 12.0 0.9 0.087 11.6 0.6 1.2 1 0 0 1 1 1 0 AFG1-like ATPase TPR_11 PF13414.1 EWM26282.1 - 2e-59 197.1 29.9 4.7e-18 64.5 2.0 6.3 6 0 0 6 6 6 6 TPR repeat TPR_1 PF00515.23 EWM26282.1 - 2.5e-44 147.1 29.9 2.2e-06 27.0 0.8 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.12 EWM26282.1 - 2.7e-36 120.5 31.7 7.4e-05 22.3 0.3 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_16 PF13432.1 EWM26282.1 - 9.4e-25 86.6 24.4 4e-08 33.7 0.9 6.5 3 3 5 8 8 8 7 Tetratricopeptide repeat TPR_12 PF13424.1 EWM26282.1 - 1.7e-23 82.3 17.5 2e-07 30.8 0.0 6.1 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 EWM26282.1 - 4e-22 76.2 20.8 0.00037 20.0 0.0 8.7 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_17 PF13431.1 EWM26282.1 - 1.8e-18 65.1 12.8 0.002 18.1 0.3 8.2 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 EWM26282.1 - 2.5e-18 64.9 22.6 0.001 19.5 0.1 9.2 4 3 5 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 EWM26282.1 - 2.5e-14 53.3 17.8 5e-05 23.5 0.4 6.4 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.1 EWM26282.1 - 9e-14 50.1 11.8 0.042 13.6 0.0 8.5 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.1 EWM26282.1 - 3.2e-11 42.9 3.6 0.0095 15.7 0.2 5.8 4 2 2 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 EWM26282.1 - 8e-08 32.3 11.8 0.009 16.1 0.1 4.7 3 3 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.12 EWM26282.1 - 0.00044 20.5 18.3 0.0097 16.2 1.7 4.5 3 1 0 3 3 3 2 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.1 EWM26282.1 - 0.00087 19.1 7.3 0.81 9.6 0.0 5.1 6 0 0 6 6 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 EWM26282.1 - 0.00097 19.4 28.3 0.6 10.6 0.5 8.2 9 0 0 9 9 7 1 Tetratricopeptide repeat DUF3856 PF12968.2 EWM26282.1 - 0.0025 17.6 9.6 0.12 12.1 0.6 4.7 3 2 0 3 3 3 1 Domain of Unknown Function (DUF3856) Sec5 PF15469.1 EWM26282.1 - 0.0065 16.2 0.4 2.1 8.0 0.0 3.4 3 0 0 3 3 3 1 Exocyst complex component Sec5 MIT PF04212.13 EWM26282.1 - 0.014 15.2 25.9 0.11 12.4 0.3 6.2 6 1 0 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 EWM26282.1 - 0.37 10.7 14.2 6.1 6.9 0.3 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat RPN7 PF10602.4 EWM26282.1 - 0.95 8.8 11.7 4.6 6.5 0.1 4.2 2 1 2 4 4 4 0 26S proteasome subunit RPN7 DUF1896 PF08989.5 EWM26282.1 - 2.1 8.1 5.7 39 4.1 0.1 3.9 4 1 0 4 4 3 0 Domain of unknown function (DUF1896) TPR_3 PF07720.7 EWM26282.1 - 9 6.2 15.6 15 5.5 0.2 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat adh_short PF00106.20 EWM26283.1 - 1.8e-29 102.7 1.5 2.4e-29 102.4 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EWM26283.1 - 1.4e-21 77.3 0.7 1.7e-21 77.1 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EWM26283.1 - 2.3e-11 43.7 0.8 3.2e-11 43.2 0.5 1.1 1 0 0 1 1 1 1 KR domain Methyltransf_11 PF08241.7 EWM26283.1 - 0.0018 18.7 0.0 0.0038 17.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain 3HCDH_N PF02737.13 EWM26283.1 - 0.0018 17.9 0.8 0.0029 17.2 0.6 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EWM26283.1 - 0.005 15.8 0.4 0.0096 14.9 0.3 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase Methyltransf_26 PF13659.1 EWM26283.1 - 0.034 14.1 0.1 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ThiI PF02568.9 EWM26283.1 - 0.047 13.1 0.2 4.3 6.7 0.0 2.2 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) Methyltransf_12 PF08242.7 EWM26283.1 - 0.089 13.2 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Eno-Rase_NADH_b PF12242.3 EWM26283.1 - 0.14 11.9 1.5 0.35 10.7 0.8 1.8 1 1 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase zf-UBR PF02207.15 EWM26284.1 - 1.7e-18 66.1 13.5 3.6e-18 65.0 9.4 1.6 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 EWM26284.1 - 1.9e-09 37.0 0.0 4.1e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Pkinase PF00069.20 EWM26285.1 - 2.9e-72 242.9 0.0 4.2e-72 242.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM26285.1 - 5e-38 130.6 0.0 7.4e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EWM26285.1 - 3.1e-07 29.6 0.1 1.5e-06 27.4 0.1 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EWM26285.1 - 0.00019 20.4 0.0 0.00041 19.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EWM26285.1 - 0.0029 16.9 0.0 0.007 15.7 0.0 1.6 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.17 EWM26285.1 - 0.015 14.6 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 EWM26285.1 - 0.019 14.7 0.0 0.036 13.7 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family adh_short PF00106.20 EWM26286.1 - 1.3e-17 64.2 0.0 1.9e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EWM26286.1 - 4.3e-07 29.7 0.0 7.2e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EWM26286.1 - 1.3e-05 24.7 0.0 1.8e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EWM26286.1 - 0.0069 15.3 0.0 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EWM26286.1 - 0.012 15.5 0.3 0.03 14.3 0.2 1.7 1 1 0 1 1 1 0 NADH(P)-binding DUF1253 PF06862.7 EWM26287.1 - 1.5e-125 419.1 0.0 8.3e-64 215.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) THF_DHG_CYH_C PF02882.14 EWM26288.1 - 1.6e-64 215.8 2.1 2.5e-64 215.2 1.0 1.6 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EWM26288.1 - 4.5e-43 146.0 0.0 7.8e-43 145.2 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.10 EWM26288.1 - 0.0028 16.4 0.5 0.021 13.6 0.1 2.1 2 0 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family WD40 PF00400.27 EWM26289.1 - 7.5e-12 44.6 0.8 0.92 9.4 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat DUF221 PF02714.10 EWM26290.1 - 9.1e-62 208.7 19.7 1.2e-61 208.4 13.6 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF221 DPM3 PF08285.6 EWM26290.1 - 0.8 9.5 3.9 5.4 6.9 0.3 3.3 2 1 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) IDO PF01231.13 EWM26292.1 - 1.3e-79 267.5 0.0 3.1e-40 137.9 0.0 3.4 3 1 0 3 3 3 3 Indoleamine 2,3-dioxygenase AAA_21 PF13304.1 EWM26293.1 - 0.0014 18.6 0.0 0.0018 18.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EWM26294.1 - 2.9e-10 40.5 0.0 5.2e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 EWM26294.1 - 3.2e-05 23.1 7.6 4.3e-05 22.7 5.3 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein SRP54 PF00448.17 EWM26294.1 - 0.021 14.2 0.2 0.038 13.4 0.0 1.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ABC_tran PF00005.22 EWM26295.1 - 4.5e-30 104.7 0.1 7.5e-30 104.0 0.1 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 EWM26295.1 - 2e-21 76.4 14.6 2.9e-21 75.8 10.1 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.1 EWM26295.1 - 2.5e-10 40.8 0.0 4.8e-07 30.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EWM26295.1 - 0.0017 17.8 0.5 0.0043 16.5 0.3 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 EWM26295.1 - 0.0054 15.9 0.0 2.9 7.0 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EWM26295.1 - 0.0099 15.0 0.1 0.019 14.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC2_membrane_2 PF12679.2 EWM26295.1 - 0.014 14.2 15.9 0.027 13.3 11.0 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_23 PF13476.1 EWM26295.1 - 0.094 13.0 1.6 0.11 12.7 0.3 1.6 2 0 0 2 2 2 0 AAA domain DUF2717 PF10911.3 EWM26295.1 - 0.12 11.9 0.0 2.9 7.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2717) ABC_tran PF00005.22 EWM26296.1 - 1.9e-13 50.8 0.0 3.2e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 EWM26296.1 - 1.5e-05 24.2 8.8 2e-05 23.7 6.1 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein SRP54 PF00448.17 EWM26296.1 - 0.022 14.2 0.1 0.042 13.3 0.0 1.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain VWA_2 PF13519.1 EWM26297.1 - 3.5e-11 43.4 1.0 4.7e-11 43.0 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.9 EWM26297.1 - 1.8e-06 27.6 0.0 3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.15 EWM26297.1 - 0.00067 19.0 21.2 0.054 13.0 3.6 3.6 3 0 0 3 3 3 2 Ubiquitin interaction motif VWA PF00092.23 EWM26297.1 - 0.0041 16.8 0.1 0.007 16.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain SUD-M PF11633.3 EWM26297.1 - 0.008 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Single-stranded poly(A) binding domain PDH PF02153.12 EWM26297.1 - 0.031 13.1 0.0 0.051 12.4 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase TrbI PF03743.9 EWM26297.1 - 0.73 9.2 5.5 1.5 8.3 3.8 1.6 1 0 0 1 1 1 0 Bacterial conjugation TrbI-like protein BUD22 PF09073.5 EWM26297.1 - 8.8 5.2 9.7 13 4.7 6.7 1.2 1 0 0 1 1 1 0 BUD22 Rep_fac_C PF08542.6 EWM26298.1 - 2.6e-22 78.6 0.0 6.1e-22 77.4 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EWM26298.1 - 8.5e-11 41.7 0.0 1.5e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EWM26298.1 - 6.4e-08 32.8 0.0 1.6e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 EWM26298.1 - 0.00023 20.8 0.0 0.00079 19.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EWM26298.1 - 0.0012 18.8 0.3 0.011 15.7 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EWM26298.1 - 0.0013 18.8 0.0 0.0049 17.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 EWM26298.1 - 0.0021 18.1 0.1 0.14 12.2 0.1 2.9 1 1 0 1 1 1 1 Sigma-54 interaction domain RuvB_N PF05496.7 EWM26298.1 - 0.0022 17.0 0.0 0.071 12.1 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EWM26298.1 - 0.016 14.9 0.2 0.096 12.4 0.2 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EWM26298.1 - 0.019 14.0 0.0 0.35 10.0 0.0 2.5 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI RdRP PF05183.7 EWM26298.1 - 0.02 13.5 0.0 0.11 11.1 0.0 1.9 1 1 0 1 1 1 0 RNA dependent RNA polymerase AAA_10 PF12846.2 EWM26298.1 - 0.065 12.6 0.0 0.19 11.1 0.0 1.6 1 1 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 EWM26298.1 - 0.071 12.9 0.2 0.18 11.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.10 EWM26298.1 - 0.12 10.9 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF2363 PF10155.4 EWM26299.1 - 4.6e-51 172.0 7.0 7.3e-51 171.3 4.8 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2363) Creb_binding PF09030.5 EWM26299.1 - 0.0081 16.3 0.1 0.25 11.5 0.0 2.4 2 0 0 2 2 2 1 Creb binding COQ7 PF03232.8 EWM26300.1 - 1.7e-24 86.2 0.0 3e-24 85.4 0.0 1.4 1 1 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Acyl_transf_1 PF00698.16 EWM26301.1 - 1.3e-57 195.5 1.6 2e-57 194.9 0.2 2.0 2 0 0 2 2 2 1 Acyl transferase domain KR PF08659.5 EWM26301.1 - 1.2e-45 155.4 2.4 2.8e-45 154.2 0.6 2.5 2 0 0 2 2 2 1 KR domain ketoacyl-synt PF00109.21 EWM26301.1 - 6.3e-42 143.8 0.1 1.9e-41 142.2 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short PF00106.20 EWM26301.1 - 3.3e-37 127.9 1.2 3.3e-37 127.9 0.9 3.2 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EWM26301.1 - 2.6e-23 82.1 0.1 1.8e-22 79.4 0.0 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 EWM26301.1 - 7.6e-20 72.1 0.0 1.5e-19 71.1 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain ADH_zinc_N PF00107.21 EWM26301.1 - 7.5e-15 54.6 0.2 4.5e-14 52.1 0.1 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PS-DH PF14765.1 EWM26301.1 - 2.5e-12 46.5 0.0 8.9e-11 41.4 0.0 2.4 1 1 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N_2 PF13602.1 EWM26301.1 - 5.6e-12 46.6 0.0 6e-11 43.3 0.0 2.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Abhydrolase_6 PF12697.2 EWM26301.1 - 9.8e-09 35.4 2.5 1e-08 35.3 0.3 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM26301.1 - 2.9e-08 33.5 0.1 3e-06 27.0 0.0 2.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family PP-binding PF00550.20 EWM26301.1 - 2.9e-08 33.8 0.0 6.8e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 EWM26301.1 - 4.7e-08 32.7 0.0 1.6e-07 31.0 0.0 1.9 2 0 0 2 2 1 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.16 EWM26301.1 - 0.032 13.6 0.0 0.081 12.3 0.0 1.7 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF2305 PF10230.4 EWM26301.1 - 0.085 12.2 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Omptin PF01278.15 EWM26301.1 - 0.62 9.1 0.3 30 3.5 0.0 2.2 2 0 0 2 2 2 0 Omptin family Melibiase PF02065.13 EWM26302.1 - 1.5e-20 73.3 0.0 3e-16 59.1 0.0 2.1 1 1 1 2 2 2 2 Melibiase Ricin_B_lectin PF00652.17 EWM26302.1 - 0.00035 20.5 0.0 0.0015 18.5 0.0 2.0 3 0 0 3 3 3 1 Ricin-type beta-trefoil lectin domain MRP-L46 PF11788.3 EWM26303.1 - 1.1e-05 25.9 0.2 0.0004 21.0 0.0 2.4 1 1 0 2 2 2 1 39S mitochondrial ribosomal protein L46 Pkinase PF00069.20 EWM26304.1 - 6.1e-77 258.2 0.0 7.5e-77 257.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM26304.1 - 4.4e-34 117.7 0.0 5.7e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EWM26304.1 - 3.9e-05 22.7 0.0 0.0063 15.5 0.0 2.2 1 1 0 2 2 2 2 Kinase-like Kdo PF06293.9 EWM26304.1 - 0.0092 15.0 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EWM26304.1 - 0.08 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Peptidase_S9_N PF02897.10 EWM26305.1 - 5.7e-105 351.2 0.0 8.1e-105 350.7 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 EWM26305.1 - 5.5e-65 218.5 0.0 1.1e-64 217.6 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family NAD_binding_10 PF13460.1 EWM26306.1 - 5.8e-20 72.0 0.2 8.1e-20 71.5 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EWM26306.1 - 6.6e-08 32.2 0.0 9.8e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EWM26306.1 - 9.5e-06 24.5 0.0 1.2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EWM26306.1 - 0.0058 15.9 0.0 0.0091 15.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EWM26306.1 - 0.0068 16.3 0.4 0.03 14.2 0.1 2.2 3 0 0 3 3 3 1 short chain dehydrogenase RibD_C PF01872.12 EWM26306.1 - 0.014 14.9 0.1 2.1 7.9 0.0 2.2 1 1 0 2 2 2 0 RibD C-terminal domain Shikimate_DH PF01488.15 EWM26306.1 - 0.014 15.4 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HIM1 PF08732.5 EWM26306.1 - 0.027 12.9 0.0 0.039 12.4 0.0 1.2 1 0 0 1 1 1 0 HIM1 KR PF08659.5 EWM26306.1 - 0.045 13.4 0.0 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 KR domain Semialdhyde_dh PF01118.19 EWM26306.1 - 0.06 13.6 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 EWM26306.1 - 0.082 11.8 0.1 0.23 10.3 0.0 1.7 2 0 0 2 2 2 0 Male sterility protein Ank PF00023.25 EWM26307.1 - 1.7e-06 27.5 0.7 9.7e-06 25.1 0.3 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 EWM26307.1 - 7.6e-06 26.1 0.3 2.2e-05 24.6 0.2 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EWM26307.1 - 3e-05 24.4 0.1 0.0013 19.2 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM26307.1 - 0.0039 17.2 0.8 0.014 15.5 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeat NnrS PF05940.7 EWM26308.1 - 0.018 13.9 0.3 0.018 13.9 0.2 1.4 2 0 0 2 2 2 0 NnrS protein DUF3670 PF12419.3 EWM26308.1 - 0.031 13.6 0.1 0.062 12.7 0.0 1.5 1 0 0 1 1 1 0 SNF2 Helicase protein DUF3185 PF11381.3 EWM26308.1 - 0.046 13.4 1.6 0.09 12.5 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) Myb_DNA-binding PF00249.26 EWM26309.1 - 1.6e-38 130.4 8.8 3.8e-13 49.2 0.4 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EWM26309.1 - 4.6e-31 106.7 11.0 4.3e-15 55.5 0.2 3.9 2 1 2 4 4 4 3 Myb-like DNA-binding domain Rap1_C PF11626.3 EWM26309.1 - 0.018 14.9 5.7 4.5 7.2 0.5 3.5 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain ABC_tran PF00005.22 EWM26310.1 - 3.1e-30 105.2 0.2 6.2e-30 104.2 0.1 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 EWM26310.1 - 4.6e-24 85.0 12.6 7.6e-24 84.3 8.8 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.1 EWM26310.1 - 2.9e-10 40.5 0.0 5.2e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EWM26310.1 - 0.0019 17.7 0.5 0.0047 16.4 0.3 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 EWM26310.1 - 0.0058 15.8 0.1 3.2 6.9 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC2_membrane_2 PF12679.2 EWM26310.1 - 0.0081 15.0 15.6 0.018 13.9 10.8 1.6 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF258 PF03193.11 EWM26310.1 - 0.011 14.9 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 EWM26310.1 - 0.043 14.1 0.5 0.098 12.9 0.1 1.7 2 0 0 2 2 2 0 AAA domain VPS9 PF02204.13 EWM26311.1 - 1.1e-14 54.2 0.0 2.1e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain SEN1_N PF12726.2 EWM26311.1 - 0.0047 15.0 0.0 0.0077 14.3 0.0 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_2 PF07724.9 EWM26312.1 - 4.4e-56 189.4 0.0 3e-52 176.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 EWM26312.1 - 1.9e-25 89.5 0.0 4.2e-13 49.6 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EWM26312.1 - 2.8e-18 65.9 0.9 1.2e-12 47.6 0.0 3.5 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.4 EWM26312.1 - 4.8e-18 64.8 0.1 1.9e-17 62.9 0.1 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 EWM26312.1 - 1e-12 48.4 16.1 2.6e-05 24.2 0.0 6.1 4 3 1 6 6 5 3 AAA ATPase domain Clp_N PF02861.15 EWM26312.1 - 2.5e-12 46.5 4.6 5.9e-08 32.5 0.5 3.6 2 1 0 2 2 2 2 Clp amino terminal domain AAA_22 PF13401.1 EWM26312.1 - 4.1e-11 43.1 0.1 5.9e-05 23.2 0.0 3.8 2 2 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EWM26312.1 - 5.4e-08 32.8 0.8 0.042 13.5 0.0 4.2 2 2 1 3 3 3 2 Archaeal ATPase Sigma54_activat PF00158.21 EWM26312.1 - 7.3e-08 32.0 0.1 1.8e-05 24.2 0.0 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_17 PF13207.1 EWM26312.1 - 7.8e-08 33.1 2.0 0.0007 20.4 0.0 3.6 2 2 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EWM26312.1 - 2.3e-07 30.7 0.0 0.014 15.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EWM26312.1 - 2.5e-07 30.3 0.0 0.0029 17.0 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 EWM26312.1 - 2.6e-06 26.7 0.1 0.052 12.7 0.0 3.4 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EWM26312.1 - 4.2e-06 27.0 0.1 0.071 13.4 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.1 EWM26312.1 - 5.5e-06 25.9 0.3 0.19 11.0 0.0 3.7 3 2 1 4 4 4 2 AAA domain DNA_pol3_delta2 PF13177.1 EWM26312.1 - 2.1e-05 24.2 0.0 5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_19 PF13245.1 EWM26312.1 - 3e-05 23.6 0.1 0.5 10.1 0.0 3.2 2 0 0 2 2 2 2 Part of AAA domain RNA_helicase PF00910.17 EWM26312.1 - 3.8e-05 23.8 0.1 0.089 12.9 0.0 3.2 3 0 0 3 3 3 1 RNA helicase NACHT PF05729.7 EWM26312.1 - 7.2e-05 22.5 0.0 0.33 10.5 0.0 3.0 3 0 0 3 3 2 2 NACHT domain RuvB_N PF05496.7 EWM26312.1 - 0.0011 18.0 2.7 0.38 9.7 0.0 3.9 3 1 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 EWM26312.1 - 0.0012 18.4 0.0 0.15 11.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain Torsin PF06309.6 EWM26312.1 - 0.0014 18.4 0.0 0.0034 17.2 0.0 1.6 1 0 0 1 1 1 1 Torsin AAA_33 PF13671.1 EWM26312.1 - 0.0025 17.7 0.0 0.11 12.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EWM26312.1 - 0.0061 16.5 0.3 3.6 7.5 0.0 3.4 2 1 1 3 3 3 1 AAA domain AAA_10 PF12846.2 EWM26312.1 - 0.0068 15.8 0.4 2.3 7.6 0.0 3.7 2 2 1 3 3 3 1 AAA-like domain Zeta_toxin PF06414.7 EWM26312.1 - 0.0069 15.4 0.0 0.12 11.4 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_3 PF07726.6 EWM26312.1 - 0.0088 15.6 0.1 4.7 6.8 0.0 3.8 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 EWM26312.1 - 0.011 16.0 2.2 4.4 7.5 0.3 3.5 3 0 0 3 3 3 0 AAA domain DUF258 PF03193.11 EWM26312.1 - 0.019 14.1 0.0 4.4 6.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 BLOC1_2 PF10046.4 EWM26312.1 - 0.035 14.2 0.4 0.5 10.5 0.0 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ABC_tran PF00005.22 EWM26312.1 - 0.039 14.2 0.1 6.4 7.0 0.0 3.3 3 0 0 3 3 3 0 ABC transporter ResIII PF04851.10 EWM26312.1 - 0.049 13.4 0.0 1.3 8.8 0.0 3.0 3 1 1 4 4 3 0 Type III restriction enzyme, res subunit KTI12 PF08433.5 EWM26312.1 - 0.074 12.2 0.0 11 5.1 0.0 3.3 3 0 0 3 3 3 0 Chromatin associated protein KTI12 Miro PF08477.8 EWM26312.1 - 0.14 12.6 0.0 21 5.6 0.0 2.9 3 0 0 3 3 2 0 Miro-like protein V_ATPase_I PF01496.14 EWM26312.1 - 1 7.1 1.5 1.5 6.5 1.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Flavoprotein PF02441.14 EWM26313.1 - 3e-42 143.3 0.0 3.8e-42 143.0 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein UCR_Fe-S_N PF10399.4 EWM26313.1 - 0.14 11.3 0.4 0.25 10.5 0.3 1.4 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal SQS_PSY PF00494.14 EWM26314.1 - 3.6e-40 137.9 0.1 6.8e-40 137.0 0.1 1.4 1 0 0 1 1 1 1 Squalene/phytoene synthase NUDIX PF00293.23 EWM26314.1 - 2e-27 95.4 0.0 4.3e-27 94.3 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain ACT_5 PF13710.1 EWM26316.1 - 9.8 6.0 20.6 12 5.7 0.1 7.1 8 0 0 8 8 8 0 ACT domain ABC_tran PF00005.22 EWM26317.1 - 4.9e-24 85.1 0.1 9.7e-22 77.7 0.0 3.1 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EWM26317.1 - 2.9e-08 34.0 0.8 3.1e-07 30.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 EWM26317.1 - 3.2e-08 33.0 0.0 1.7e-07 30.6 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Chromo PF00385.19 EWM26317.1 - 3e-07 29.9 1.0 7.2e-07 28.7 0.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_17 PF13207.1 EWM26317.1 - 0.00081 20.1 1.1 0.0055 17.5 0.7 2.6 1 1 0 1 1 1 1 AAA domain Sigma70_r1_1 PF03979.9 EWM26317.1 - 0.0017 18.2 2.2 0.54 10.2 1.6 2.9 2 0 0 2 2 2 1 Sigma-70 factor, region 1.1 SbcCD_C PF13558.1 EWM26317.1 - 0.0018 18.1 0.0 0.0059 16.4 0.0 1.8 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EWM26317.1 - 0.0093 15.4 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Miro PF08477.8 EWM26317.1 - 0.015 15.7 0.1 0.054 13.9 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein AAA_33 PF13671.1 EWM26317.1 - 0.022 14.6 0.0 0.051 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 EWM26317.1 - 0.028 14.2 0.0 0.028 14.2 0.0 2.7 3 1 0 3 3 3 0 Domain of unknown function DUF87 AAA_22 PF13401.1 EWM26317.1 - 0.034 14.2 0.0 0.42 10.7 0.0 2.6 3 0 0 3 3 2 0 AAA domain MobB PF03205.9 EWM26317.1 - 0.044 13.4 1.3 0.13 11.9 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EWM26317.1 - 0.047 12.8 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EWM26317.1 - 0.052 13.5 0.0 0.21 11.5 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.24 EWM26317.1 - 0.057 13.6 0.3 0.64 10.2 0.0 2.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EWM26317.1 - 0.064 12.8 0.1 3.6 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EWM26317.1 - 0.086 12.6 3.2 0.11 12.2 0.0 2.3 2 1 0 2 2 2 0 Dynamin family AAA_16 PF13191.1 EWM26317.1 - 0.11 12.5 0.0 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 EWM26317.1 - 0.11 11.9 0.1 0.29 10.5 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain AAA_18 PF13238.1 EWM26317.1 - 1 9.6 6.0 0.83 9.9 0.1 3.1 2 2 0 2 2 2 0 AAA domain Dynein_light PF01221.13 EWM26319.1 - 6.9e-24 83.6 0.9 7.5e-24 83.5 0.6 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 WD40 PF00400.27 EWM26320.1 - 2.3e-30 103.3 17.1 2.2e-05 24.1 0.1 8.5 8 1 0 8 8 8 7 WD domain, G-beta repeat PQQ_3 PF13570.1 EWM26320.1 - 9.9e-08 32.0 1.9 2.5 8.5 0.0 5.9 5 0 0 5 5 5 2 PQQ-like domain Nup160 PF11715.3 EWM26320.1 - 0.017 13.2 0.2 2.1 6.3 0.0 2.8 1 1 1 2 2 2 0 Nucleoporin Nup120/160 DUF3312 PF11768.3 EWM26320.1 - 0.051 11.8 0.0 5.8 5.0 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3312) FtsJ PF01728.14 EWM26321.1 - 1.3e-64 217.4 0.0 1.6e-64 217.2 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Gelsolin PF00626.17 EWM26322.1 - 5.6e-47 157.3 0.0 2.1e-10 40.1 0.0 7.0 7 1 0 7 7 7 6 Gelsolin repeat VHP PF02209.14 EWM26322.1 - 5e-12 45.3 0.8 8.8e-12 44.5 0.6 1.4 1 0 0 1 1 1 1 Villin headpiece domain Sld5 PF05916.6 EWM26323.1 - 2.9e-19 69.3 0.1 4.3e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein LEA_2 PF03168.8 EWM26325.1 - 0.13 12.6 0.2 0.28 11.6 0.2 1.5 1 0 0 1 1 1 0 Late embryogenesis abundant protein DUF566 PF04484.7 EWM26325.1 - 0.57 9.6 7.2 0.76 9.2 5.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Secretin_N_2 PF07655.8 EWM26325.1 - 0.59 10.5 13.0 0.91 9.9 9.0 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain HMG_box PF00505.14 EWM26326.1 - 4.3e-16 58.9 12.8 4.3e-15 55.7 1.3 2.5 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 EWM26326.1 - 7.8e-12 45.3 2.5 7.8e-12 45.3 1.7 2.9 3 0 0 3 3 3 2 HMG-box domain DUF2763 PF10961.3 EWM26326.1 - 3.7 8.0 8.3 3.6 8.0 0.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2763) ABC_membrane PF00664.18 EWM26327.1 - 1e-55 189.1 12.4 5e-29 101.5 3.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EWM26327.1 - 2.7e-43 147.5 0.0 1.8e-26 93.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.1 EWM26327.1 - 4.1e-09 35.8 0.2 0.00088 18.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 EWM26327.1 - 1.3e-07 31.9 0.0 0.16 11.9 0.0 4.2 4 0 0 4 4 4 2 AAA domain SMC_N PF02463.14 EWM26327.1 - 2.9e-06 26.6 0.0 0.032 13.4 0.0 3.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.18 EWM26327.1 - 1.3e-05 25.0 0.1 0.18 11.6 0.0 2.3 2 0 0 2 2 2 2 Dynamin family AAA_23 PF13476.1 EWM26327.1 - 5.4e-05 23.6 0.0 0.38 11.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EWM26327.1 - 8.5e-05 22.6 0.2 0.057 13.4 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain T2SE PF00437.15 EWM26327.1 - 0.00012 21.0 0.2 0.025 13.4 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.1 EWM26327.1 - 0.00016 21.1 0.1 0.48 9.7 0.0 3.0 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 EWM26327.1 - 0.00016 21.6 1.4 0.031 14.2 0.2 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_17 PF13207.1 EWM26327.1 - 0.00046 20.9 0.0 0.3 11.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EWM26327.1 - 0.0013 19.2 1.6 0.036 14.5 0.3 2.4 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 EWM26327.1 - 0.0026 17.8 0.3 6.2 6.9 0.0 3.3 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EWM26327.1 - 0.0054 16.2 0.3 0.25 10.7 0.1 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_18 PF13238.1 EWM26327.1 - 0.013 15.8 0.0 2.9 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EWM26327.1 - 0.017 14.5 1.2 6.3 6.1 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain ABC_ATPase PF09818.4 EWM26327.1 - 0.02 13.4 0.1 1.1 7.7 0.0 2.6 3 0 0 3 3 3 0 Predicted ATPase of the ABC class Arch_ATPase PF01637.13 EWM26327.1 - 0.022 14.4 0.4 0.21 11.2 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase MobB PF03205.9 EWM26327.1 - 0.023 14.3 1.3 3.6 7.3 0.1 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EWM26327.1 - 0.026 14.3 0.0 8.2 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EWM26327.1 - 0.034 13.9 0.2 0.066 13.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF258 PF03193.11 EWM26327.1 - 0.058 12.5 0.3 8.5 5.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 EWM26327.1 - 0.077 12.7 0.1 2.7 7.6 0.0 2.9 3 0 0 3 3 3 0 NTPase AAA_14 PF13173.1 EWM26327.1 - 0.097 12.5 0.1 0.63 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 EWM26327.1 - 0.22 10.9 0.2 4 6.8 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain cobW PF02492.14 EWM26327.1 - 0.48 9.8 1.7 18 4.7 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain 3HCDH_N PF02737.13 EWM26329.1 - 3.2e-57 193.0 0.1 4.5e-57 192.6 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EWM26329.1 - 9.8e-29 99.6 0.0 4.2e-28 97.5 0.0 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EWM26329.1 - 0.00041 20.2 0.1 0.00076 19.3 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.9 EWM26329.1 - 0.015 14.7 0.4 0.024 14.0 0.3 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF2680 PF10925.3 EWM26329.1 - 0.029 14.2 0.3 0.55 10.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) DUF1465 PF07323.7 EWM26329.1 - 0.071 12.6 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) 2-Hacid_dh_C PF02826.14 EWM26329.1 - 0.084 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EWM26329.1 - 0.11 12.9 3.5 0.58 10.6 2.5 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent zf-CCCH PF00642.19 EWM26330.1 - 4.1e-12 45.4 14.2 2.7e-06 26.9 2.0 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EWM26330.1 - 7.8e-09 35.2 0.0 1.3e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EWM26330.1 - 7.3e-05 22.3 0.1 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tachystatin_B PF11478.3 EWM26330.1 - 0.0032 17.1 3.1 0.011 15.4 0.6 2.8 2 0 0 2 2 2 1 Antimicrobial chitin binding protein tachystatin B RRM_6 PF14259.1 EWM26330.1 - 0.029 14.3 0.1 0.054 13.4 0.1 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) TerC PF03741.11 EWM26331.1 - 4.9e-52 176.0 2.9 6.6e-52 175.6 2.0 1.2 1 0 0 1 1 1 1 Integral membrane protein TerC family Myc_N PF01056.13 EWM26332.1 - 0.0032 16.6 1.5 0.0032 16.6 1.0 2.0 2 0 0 2 2 2 1 Myc amino-terminal region Na_trans_assoc PF06512.8 EWM26332.1 - 0.034 14.1 5.9 0.027 14.4 1.2 2.2 2 0 0 2 2 2 0 Sodium ion transport-associated Ribosomal_60s PF00428.14 EWM26332.1 - 0.066 13.6 12.1 0.098 13.0 5.4 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein CENP-B_dimeris PF09026.5 EWM26332.1 - 0.26 11.5 7.1 0.84 9.9 4.9 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.7 EWM26332.1 - 0.57 8.0 6.2 0.79 7.5 4.3 1.1 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 EWM26332.1 - 4.7 6.7 10.6 9.8 5.6 7.4 1.4 1 0 0 1 1 1 0 Nucleoplasmin ABC_tran PF00005.22 EWM26333.1 - 3.9e-13 49.8 0.0 1.5e-12 47.9 0.0 2.0 1 1 0 1 1 1 1 ABC transporter HEAT PF02985.17 EWM26333.1 - 4.6e-08 32.4 0.1 0.0043 17.0 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.1 EWM26333.1 - 1.4e-06 28.4 0.5 0.0015 18.7 0.0 2.9 2 1 1 3 3 3 2 HEAT repeats Ipi1_N PF12333.3 EWM26333.1 - 4e-06 26.7 0.0 0.28 11.1 0.0 3.4 2 1 1 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation AAA_21 PF13304.1 EWM26333.1 - 1.3e-05 25.3 0.0 0.00099 19.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain HEAT_EZ PF13513.1 EWM26333.1 - 0.0019 18.6 5.1 0.78 10.3 0.0 4.9 6 0 0 6 6 6 1 HEAT-like repeat Cnd1 PF12717.2 EWM26333.1 - 0.0037 17.1 0.1 0.011 15.6 0.1 1.8 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Arch_ATPase PF01637.13 EWM26333.1 - 0.0037 16.9 0.0 0.0094 15.6 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase Adaptin_N PF01602.15 EWM26333.1 - 0.02 13.2 0.9 0.033 12.5 0.7 1.4 1 1 0 1 1 1 0 Adaptin N terminal region DUF2454 PF10521.4 EWM26333.1 - 0.029 13.3 0.1 0.078 11.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2454) MMR_HSR1 PF01926.18 EWM26333.1 - 0.031 14.2 0.0 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.1 EWM26333.1 - 0.035 14.0 0.0 0.34 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EWM26333.1 - 0.039 14.2 0.0 0.14 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EWM26333.1 - 0.039 13.4 0.0 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Vac14_Fab1_bd PF12755.2 EWM26333.1 - 0.041 14.2 0.1 0.25 11.7 0.0 2.3 1 1 0 2 2 2 0 Vacuolar 14 Fab1-binding region AAA_15 PF13175.1 EWM26333.1 - 0.056 12.4 0.0 0.24 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain DUF1981 PF09324.5 EWM26333.1 - 0.078 12.5 0.4 0.54 9.8 0.0 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF1981) AAA PF00004.24 EWM26333.1 - 0.089 12.9 0.0 0.52 10.5 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UTP15_C PF09384.5 EWM26333.1 - 0.13 11.8 0.0 0.35 10.5 0.0 1.7 1 0 0 1 1 1 0 UTP15 C terminal DUF326 PF03860.11 EWM26333.1 - 2.4 8.1 5.1 4.1 7.3 0.3 2.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF326) UPF0640 PF15114.1 EWM26334.1 - 3.4e-06 26.4 0.0 6.1e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family UPF0640 TIP41 PF04176.8 EWM26335.1 - 6.8e-39 133.0 0.1 2.5e-38 131.1 0.1 1.8 1 1 0 1 1 1 1 TIP41-like family Sugar_tr PF00083.19 EWM26336.1 - 9.5e-27 93.6 13.1 1.6e-15 56.6 0.0 2.3 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EWM26336.1 - 2e-24 86.0 31.8 3.2e-24 85.3 22.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EWM26336.1 - 1.1e-06 27.3 11.0 0.0021 16.5 1.9 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein ATG22 PF11700.3 EWM26336.1 - 0.0037 15.8 11.0 0.064 11.7 2.3 2.4 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like PP2C PF00481.16 EWM26338.1 - 2e-33 115.8 0.0 4.2e-33 114.8 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EWM26338.1 - 0.00023 20.9 0.0 0.066 12.9 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EWM26338.1 - 0.0041 16.5 0.0 1.4 8.2 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C SNARE_assoc PF09335.6 EWM26339.1 - 3.2e-15 56.4 7.7 1.2e-08 35.2 0.4 3.3 4 0 0 4 4 4 2 SNARE associated Golgi protein APG12 PF04110.8 EWM26340.1 - 3.6e-23 81.5 0.0 5.5e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 EWM26340.1 - 0.00014 21.8 0.0 0.00019 21.3 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like FAD_binding_3 PF01494.14 EWM26342.1 - 1.7e-20 73.3 3.9 4.2e-11 42.4 0.1 2.4 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EWM26342.1 - 3e-08 32.9 0.4 2.3e-06 26.7 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EWM26342.1 - 4e-07 29.9 0.2 2.1e-06 27.6 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EWM26342.1 - 1.9e-06 27.0 0.4 0.008 15.1 0.3 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EWM26342.1 - 4.3e-05 23.4 0.0 7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EWM26342.1 - 5.7e-05 22.0 0.0 0.00013 20.9 0.0 1.5 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox PF00070.22 EWM26342.1 - 6.4e-05 23.2 0.2 0.00023 21.4 0.1 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EWM26342.1 - 9.4e-05 21.4 2.2 0.00019 20.4 1.5 1.5 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 EWM26342.1 - 0.00018 20.2 0.3 0.15 10.6 0.0 3.0 3 0 0 3 3 3 1 Tryptophan halogenase Thi4 PF01946.12 EWM26342.1 - 0.0012 18.0 0.1 0.0023 17.0 0.1 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EWM26342.1 - 0.0016 16.9 0.6 0.003 16.1 0.4 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EWM26342.1 - 0.0018 18.3 0.3 0.0066 16.5 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EWM26342.1 - 0.0066 16.2 0.4 0.73 9.5 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding 3HCDH_N PF02737.13 EWM26342.1 - 0.014 15.0 0.6 0.025 14.2 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EWM26342.1 - 0.021 13.7 0.4 0.031 13.1 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Amino_oxidase PF01593.19 EWM26342.1 - 0.023 13.7 0.2 0.43 9.5 0.1 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase IlvN PF07991.7 EWM26342.1 - 0.034 13.4 0.3 0.064 12.6 0.2 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain ApbA PF02558.11 EWM26342.1 - 0.05 13.0 1.0 0.13 11.6 0.4 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 EWM26342.1 - 0.058 12.5 0.1 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EWM26342.1 - 0.067 12.9 0.1 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.16 EWM26342.1 - 0.11 12.0 1.4 0.13 11.8 0.2 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 EWM26342.1 - 0.15 12.1 0.1 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EWM26342.1 - 0.36 10.7 3.2 2.4 8.1 1.0 2.6 2 1 0 2 2 2 0 NADH(P)-binding Mito_carr PF00153.22 EWM26343.1 - 6.4e-64 211.7 0.1 4e-21 74.5 0.1 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Aldolase PF01081.14 EWM26345.1 - 8.4e-20 70.7 0.5 1.7e-17 63.2 0.2 2.1 2 0 0 2 2 2 2 KDPG and KHG aldolase 3HCDH_N PF02737.13 EWM26347.1 - 1.8e-57 193.9 1.5 1.8e-57 193.9 1.1 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH PF00378.15 EWM26347.1 - 5.6e-51 173.0 0.0 1e-50 172.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family 3HCDH PF00725.17 EWM26347.1 - 3.9e-28 97.6 0.0 7.1e-20 71.2 0.0 2.8 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_7 PF13241.1 EWM26347.1 - 1.2e-05 25.4 0.2 3.3e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox PF00070.22 EWM26347.1 - 0.00065 20.0 2.4 0.0023 18.3 1.7 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.10 EWM26347.1 - 0.0013 18.5 0.1 0.0043 16.8 0.0 2.0 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DAO PF01266.19 EWM26347.1 - 0.0014 17.5 0.2 0.0021 17.0 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DFP PF04127.10 EWM26347.1 - 0.014 14.9 0.6 0.014 14.9 0.4 1.8 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein F420_oxidored PF03807.12 EWM26347.1 - 0.054 13.9 0.9 0.15 12.4 0.6 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.16 EWM26347.1 - 0.067 12.7 1.2 0.15 11.5 0.5 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Exo_endo_phos PF03372.18 EWM26348.1 - 1.2e-11 45.0 0.0 1.6e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PFK PF00365.15 EWM26350.1 - 5.9e-32 110.7 0.5 9.5e-32 110.0 0.3 1.2 1 0 0 1 1 1 1 Phosphofructokinase Abhydrolase_5 PF12695.2 EWM26350.1 - 0.086 12.5 0.0 3.4 7.4 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family vATP-synt_AC39 PF01992.11 EWM26351.1 - 1.1e-42 146.3 0.3 3.6e-42 144.6 0.2 1.6 1 1 0 1 1 1 1 ATP synthase (C/AC39) subunit PIP5K PF01504.13 EWM26352.1 - 1.2e-50 171.9 0.0 6.4e-25 87.7 0.0 2.1 2 0 0 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase zf-CSL PF05207.8 EWM26353.1 - 1.3e-23 82.1 1.2 1.8e-23 81.7 0.9 1.2 1 0 0 1 1 1 1 CSL zinc finger Peptidase_M9 PF01752.12 EWM26353.1 - 0.13 11.1 0.0 0.16 10.8 0.0 1.0 1 0 0 1 1 1 0 Collagenase DUF4539 PF15072.1 EWM26354.1 - 2.9e-13 49.2 0.0 4.6e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) Porin_3 PF01459.17 EWM26355.1 - 0.013 14.7 0.0 0.015 14.5 0.0 1.0 1 0 0 1 1 1 0 Eukaryotic porin Arf PF00025.16 EWM26356.1 - 3.9e-61 205.3 0.3 4.9e-61 204.9 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EWM26356.1 - 1.7e-12 47.0 0.0 2.3e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EWM26356.1 - 6.1e-12 44.9 0.1 8.6e-11 41.1 0.0 2.0 1 1 1 2 2 2 1 G-protein alpha subunit Miro PF08477.8 EWM26356.1 - 1.3e-11 45.0 0.0 1.9e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EWM26356.1 - 2.3e-09 36.7 0.0 3.1e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EWM26356.1 - 3.6e-09 36.1 0.0 4.8e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EWM26356.1 - 2.1e-08 34.1 0.0 3e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FAD_binding_4 PF01565.18 EWM26357.1 - 2.9e-12 46.2 0.1 5.7e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.9 EWM26357.1 - 0.0031 17.1 0.2 0.0052 16.4 0.1 1.4 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase Ribosomal_S3_C PF00189.15 EWM26358.1 - 1.2e-17 63.8 1.0 2.3e-17 62.9 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EWM26358.1 - 6.3e-11 41.6 0.1 1.1e-10 40.9 0.1 1.4 1 0 0 1 1 1 1 KH domain Ribosomal_L6 PF00347.18 EWM26358.1 - 0.0065 16.9 0.3 2.8 8.5 0.0 2.8 3 0 0 3 3 3 2 Ribosomal protein L6 Aldedh PF00171.17 EWM26359.1 - 1.6e-166 554.2 0.3 1.9e-166 553.9 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ldh_2 PF02615.9 EWM26359.1 - 0.051 12.2 0.6 0.081 11.6 0.4 1.2 1 0 0 1 1 1 0 Malate/L-lactate dehydrogenase DEAD PF00270.24 EWM26360.1 - 7.5e-42 142.6 0.0 1.3e-41 141.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EWM26360.1 - 3.5e-20 71.6 0.0 9.5e-20 70.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EWM26360.1 - 9.7e-20 69.8 0.0 1.9e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EWM26360.1 - 0.00016 21.5 0.0 0.00049 19.9 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EWM26360.1 - 0.071 13.2 0.3 0.48 10.5 0.2 2.5 1 1 0 1 1 1 0 AAA domain Ribosomal_L4 PF00573.17 EWM26361.1 - 0.34 10.2 7.8 0.54 9.6 5.4 1.3 1 0 0 1 1 1 0 Ribosomal protein L4/L1 family p450 PF00067.17 EWM26362.1 - 7.4e-76 255.5 0.0 2.4e-60 204.3 0.0 3.2 2 1 0 2 2 2 2 Cytochrome P450 p450 PF00067.17 EWM26363.1 - 6.9e-76 255.6 0.0 2.4e-60 204.4 0.0 3.2 2 1 0 2 2 2 2 Cytochrome P450 Lyase_1 PF00206.15 EWM26364.1 - 2.2e-112 375.3 0.0 3.1e-112 374.7 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EWM26364.1 - 1.5e-25 89.0 0.7 9e-25 86.5 0.3 2.4 1 1 1 2 2 2 1 Fumarase C C-terminus Methyltransf_15 PF09445.5 EWM26365.1 - 3.5e-24 85.2 0.0 5.1e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.10 EWM26365.1 - 6.6e-08 32.1 0.0 1e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_26 PF13659.1 EWM26365.1 - 3e-07 30.4 0.0 4.7e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EWM26365.1 - 2.2e-05 24.1 0.0 3.3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 EWM26365.1 - 9.5e-05 22.9 0.0 0.00021 21.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MethyltransfD12 PF02086.10 EWM26365.1 - 0.018 14.5 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase SARG PF15385.1 EWM26365.1 - 0.031 13.6 1.4 0.042 13.2 1.0 1.1 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein MTS PF05175.9 EWM26365.1 - 0.034 13.5 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_24 PF13578.1 EWM26365.1 - 0.057 14.2 0.0 0.11 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Nol1_Nop2_Fmu PF01189.12 EWM26365.1 - 0.058 12.7 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 NOL1/NOP2/sun family DUF3419 PF11899.3 EWM26365.1 - 0.17 10.5 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) Methyltransf_26 PF13659.1 EWM26366.1 - 1.4e-07 31.5 0.2 3.9e-07 30.0 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 EWM26366.1 - 2.1e-05 23.4 0.1 0.00034 19.4 0.0 2.5 3 0 0 3 3 3 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 EWM26366.1 - 0.00012 21.7 0.1 0.67 9.5 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 EWM26366.1 - 0.0017 18.6 0.0 0.0062 16.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EWM26366.1 - 0.0047 16.5 0.1 0.0092 15.5 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.12 EWM26366.1 - 0.0054 15.8 0.0 0.16 10.9 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase DUF1388 PF07142.7 EWM26366.1 - 0.016 14.8 4.4 0.038 13.7 3.0 1.6 1 0 0 1 1 1 0 Repeat of unknown function (DUF1388) MTS PF05175.9 EWM26366.1 - 0.018 14.4 0.2 0.12 11.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_18 PF12847.2 EWM26366.1 - 0.035 14.6 1.6 0.65 10.6 1.1 2.5 1 1 0 1 1 1 0 Methyltransferase domain Peptidase_M48 PF01435.13 EWM26367.1 - 3.1e-36 125.0 0.0 4.2e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_U49 PF10463.4 EWM26367.1 - 0.035 13.8 0.1 10 5.8 0.0 2.4 2 0 0 2 2 2 0 Peptidase U49 Peptidase_C48 PF02902.14 EWM26369.1 - 2.1e-33 115.7 0.1 3.3e-33 115.1 0.1 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Methyltransf_32 PF13679.1 EWM26370.1 - 2.6e-16 59.6 0.7 4.1e-16 58.9 0.5 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM26370.1 - 2.3e-12 46.7 0.0 3.9e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM26370.1 - 1.4e-09 38.4 0.0 2.9e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM26370.1 - 6.3e-09 35.8 0.3 3.6e-08 33.4 0.1 2.2 2 1 0 3 3 3 1 Methyltransferase domain TRM13 PF05206.9 EWM26370.1 - 9.1e-09 34.9 0.1 2.2e-08 33.6 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase TRM13 Methyltransf_4 PF02390.12 EWM26370.1 - 4.1e-07 29.2 0.0 7.7e-07 28.3 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EWM26370.1 - 9e-06 25.1 0.0 1.5e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EWM26370.1 - 3e-05 24.3 0.1 7.2e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM26370.1 - 0.00012 22.5 0.0 0.0003 21.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM26370.1 - 0.00056 20.3 0.0 0.0015 19.0 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM26370.1 - 0.008 15.9 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 EWM26370.1 - 0.15 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) TLD PF07534.11 EWM26371.1 - 3.8e-33 114.4 0.6 6e-33 113.7 0.4 1.3 1 0 0 1 1 1 1 TLD RhoGAP PF00620.22 EWM26371.1 - 2.3e-11 43.5 0.0 7.5e-11 41.8 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain ELMO_CED12 PF04727.8 EWM26371.1 - 1e-07 31.6 0.0 2.3e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family RUN PF02759.14 EWM26371.1 - 2e-07 30.8 0.0 5.6e-07 29.3 0.0 1.8 1 1 0 1 1 1 1 RUN domain Ubie_methyltran PF01209.13 EWM26372.1 - 9.4e-32 109.9 0.0 1.2e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 EWM26372.1 - 1.9e-11 44.2 0.0 4.5e-11 43.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM26372.1 - 1.3e-08 35.4 0.1 2.2e-08 34.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM26372.1 - 6.9e-08 32.2 0.0 9.3e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM26372.1 - 1.5e-07 31.8 0.0 2.5e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM26372.1 - 4.5e-07 30.1 0.0 7.7e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM26372.1 - 1.7e-06 27.8 0.0 2.3e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM26372.1 - 0.00015 21.8 0.0 0.00028 20.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EWM26372.1 - 0.0002 20.5 0.1 0.013 14.5 0.0 2.0 1 1 1 2 2 2 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 EWM26372.1 - 0.018 14.5 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Metallophos PF00149.23 EWM26373.1 - 5.5e-42 143.4 0.1 6.9e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase tRNA-synt_1 PF00133.17 EWM26374.1 - 2.5e-212 706.1 0.0 3.4e-212 705.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EWM26374.1 - 3.4e-25 88.5 0.0 4.9e-24 84.8 0.0 2.2 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EWM26374.1 - 2.1e-18 66.2 0.1 3.5e-06 25.9 0.1 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EWM26374.1 - 1.3e-05 24.5 0.0 2.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Neurensin PF14927.1 EWM26375.1 - 0.029 13.7 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 Neurensin Sec3_C PF09763.4 EWM26378.1 - 1.7e-34 119.0 0.7 3.2e-21 75.1 0.0 4.5 4 1 1 5 5 5 4 Exocyst complex component Sec3 DUF1488 PF07369.6 EWM26378.1 - 0.024 14.4 1.1 4 7.3 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1488) CENP-Q PF13094.1 EWM26378.1 - 0.079 12.9 2.9 0.22 11.5 2.0 1.7 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF972 PF06156.8 EWM26378.1 - 0.96 9.8 4.9 1.7 9.0 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF4404 PF14357.1 EWM26378.1 - 6.2 7.3 10.8 2.3 8.6 1.7 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Tropomyosin_1 PF12718.2 EWM26378.1 - 9.7 6.0 12.8 7.8 6.3 1.6 2.8 3 0 0 3 3 3 0 Tropomyosin like PHD_2 PF13831.1 EWM26379.1 - 7.6e-08 31.5 8.5 7.6e-08 31.5 5.9 2.3 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 EWM26379.1 - 1.8e-05 24.3 10.6 1.8e-05 24.3 7.3 3.9 4 0 0 4 4 4 1 PHD-finger zf-HC5HC2H PF13771.1 EWM26379.1 - 0.0011 19.0 4.6 0.0011 19.0 3.2 3.3 3 0 0 3 3 3 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EWM26379.1 - 0.0041 17.0 22.4 0.0071 16.3 0.9 4.4 4 0 0 4 4 4 2 PHD-zinc-finger like domain zf-C2H2 PF00096.21 EWM26379.1 - 0.043 14.1 0.1 0.043 14.1 0.1 3.0 4 0 0 4 4 4 0 Zinc finger, C2H2 type NPIP PF06409.6 EWM26379.1 - 0.57 8.8 3.5 1 8.0 2.4 1.3 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) Nipped-B_C PF12830.2 EWM26380.1 - 2.1e-40 138.3 0.0 6.5e-39 133.5 0.0 3.0 2 1 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 EWM26380.1 - 2.7e-08 33.5 1.0 2.1e-05 24.3 0.1 2.6 2 0 0 2 2 2 2 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 EWM26380.1 - 1e-05 25.4 0.0 0.11 12.2 0.0 2.5 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EWM26380.1 - 8.7e-05 22.7 4.0 0.088 13.0 0.0 3.5 2 2 1 3 3 3 3 HEAT repeats HEAT PF02985.17 EWM26380.1 - 0.036 14.1 10.8 13 6.2 0.0 6.1 6 0 0 6 6 6 0 HEAT repeat HEAT_EZ PF13513.1 EWM26380.1 - 0.11 12.9 11.7 0.8 10.2 0.0 6.6 6 1 1 7 7 7 0 HEAT-like repeat CoA_binding PF02629.14 EWM26381.1 - 1.6e-25 89.4 0.6 1.6e-25 89.4 0.4 2.1 2 1 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EWM26381.1 - 3.2e-25 88.5 0.1 4.9e-25 87.9 0.1 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EWM26381.1 - 3.1e-09 36.5 0.0 5.9e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EWM26381.1 - 6.4e-05 23.0 0.1 0.00039 20.5 0.0 2.1 2 0 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.17 EWM26381.1 - 0.011 16.1 0.2 0.036 14.5 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold MVL PF12151.3 EWM26381.1 - 0.14 11.8 0.4 0.53 9.9 0.3 2.1 1 0 0 1 1 1 0 Mannan-binding protein Abhydrolase_6 PF12697.2 EWM26382.1 - 2.1e-24 86.6 1.5 2.8e-24 86.2 1.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM26382.1 - 1.5e-09 37.7 0.0 2e-09 37.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EWM26382.1 - 1.5e-07 31.2 0.0 4.4e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EWM26382.1 - 6.1e-06 26.0 0.0 1.4e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 EWM26382.1 - 0.0088 16.2 0.0 0.013 15.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 EWM26382.1 - 0.06 12.9 0.1 0.25 10.9 0.1 1.8 1 1 0 1 1 1 0 PGAP1-like protein MFS_1 PF07690.11 EWM26383.1 - 2.5e-24 85.6 17.2 4.1e-13 48.7 2.5 2.8 3 0 0 3 3 3 2 Major Facilitator Superfamily RRM_2 PF04059.7 EWM26384.1 - 6.4e-46 154.2 0.6 1.3e-45 153.3 0.4 1.5 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.17 EWM26384.1 - 0.00054 19.5 0.1 0.35 10.5 0.1 3.9 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FxsA PF04186.8 EWM26384.1 - 0.095 12.3 0.3 0.21 11.2 0.2 1.5 1 0 0 1 1 1 0 FxsA cytoplasmic membrane protein RRM_2 PF04059.7 EWM26385.1 - 6.4e-46 154.2 0.6 1.3e-45 153.3 0.4 1.5 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.17 EWM26385.1 - 0.00054 19.5 0.1 0.35 10.5 0.1 3.9 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FxsA PF04186.8 EWM26385.1 - 0.095 12.3 0.3 0.21 11.2 0.2 1.5 1 0 0 1 1 1 0 FxsA cytoplasmic membrane protein SNF2_N PF00176.18 EWM26386.1 - 7.3e-55 185.8 0.0 1e-54 185.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EWM26386.1 - 8.3e-13 48.0 0.0 1.9e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AP2 PF00847.15 EWM26386.1 - 9.6e-12 44.8 0.8 7.6e-05 22.7 0.1 2.7 2 0 0 2 2 2 2 AP2 domain HDA2-3 PF11496.3 EWM26386.1 - 0.0018 17.1 0.0 0.0035 16.2 0.0 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 EWM26386.1 - 0.014 14.9 0.0 0.031 13.7 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase Myb_DNA-binding PF00249.26 EWM26386.1 - 0.017 15.1 0.0 13 5.9 0.0 3.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain RRM_1 PF00076.17 EWM26387.1 - 1.2e-14 53.6 0.0 1.7e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM26387.1 - 7.1e-13 48.3 0.0 1e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM26387.1 - 9.4e-10 38.2 0.0 1.5e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) adh_short_C2 PF13561.1 EWM26388.1 - 9.3e-65 218.7 0.1 1.8e-64 217.8 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EWM26388.1 - 3.4e-05 23.8 2.0 5e-05 23.2 0.9 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EWM26388.1 - 0.0016 18.1 1.3 0.0044 16.7 0.9 1.8 1 1 0 1 1 1 1 KR domain Pkinase PF00069.20 EWM26389.1 - 2e-72 243.4 0.0 2.4e-72 243.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM26389.1 - 8.1e-44 149.6 0.0 1e-43 149.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EWM26389.1 - 0.0007 18.6 0.0 0.0013 17.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EWM26389.1 - 0.081 12.6 0.2 1.7 8.2 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EWM26389.1 - 0.096 12.0 0.1 0.2 10.9 0.1 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Inositol_P PF00459.20 EWM26390.1 - 3.9e-64 216.5 0.0 4.7e-64 216.3 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Porin_3 PF01459.17 EWM26391.1 - 0.11 11.7 0.1 0.12 11.6 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic porin Peptidase_C14 PF00656.17 EWM26392.1 - 3.3e-14 53.2 0.0 3.6e-14 53.0 0.0 1.0 1 0 0 1 1 1 1 Caspase domain zf-C2H2 PF00096.21 EWM26393.1 - 0.027 14.8 0.3 0.049 13.9 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type Beta-lactamase PF00144.19 EWM26394.1 - 7.9e-29 100.7 0.0 5.3e-28 97.9 0.0 2.1 1 1 0 1 1 1 1 Beta-lactamase ABM PF03992.11 EWM26395.1 - 0.0047 16.9 4.8 4 7.5 0.6 3.5 2 2 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Peptidase_C14 PF00656.17 EWM26396.1 - 1.7e-15 57.4 0.0 2.4e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Tocopherol_cycl PF14249.1 EWM26397.1 - 7.4e-06 24.8 0.0 0.016 13.9 0.0 3.2 3 0 0 3 3 3 3 Tocopherol cyclase NosL PF05573.7 EWM26398.1 - 0.13 11.9 0.3 0.22 11.2 0.2 1.3 1 0 0 1 1 1 0 NosL UvrD_C PF13361.1 EWM26399.1 - 4.3e-15 56.0 0.0 5.9e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.1 EWM26399.1 - 1.1e-06 28.7 0.0 2.6e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Got1 PF04178.7 EWM26400.1 - 1.6e-21 76.5 12.0 3e-21 75.7 8.3 1.4 1 1 0 1 1 1 1 Got1/Sft2-like family Hanta_G1 PF01567.11 EWM26400.1 - 0.031 12.5 0.0 0.045 12.0 0.0 1.2 1 0 0 1 1 1 0 Hantavirus glycoprotein G1 Methyltransf_11 PF08241.7 EWM26403.1 - 2.4e-09 37.5 0.0 4.8e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM26403.1 - 4.2e-06 26.4 0.0 6.4e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM26403.1 - 0.00034 20.9 0.0 0.00065 20.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM26403.1 - 0.00048 19.8 0.0 0.00075 19.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EWM26403.1 - 0.00096 18.3 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EWM26403.1 - 0.0017 18.7 0.0 0.0034 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 EWM26403.1 - 0.037 12.3 0.0 0.049 11.9 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ribonuc_red_sm PF00268.16 EWM26406.1 - 5.3e-10 38.7 0.0 7e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain PGK PF00162.14 EWM26407.1 - 2.4e-165 549.7 0.5 2.8e-165 549.5 0.3 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Mur_ligase PF01225.20 EWM26407.1 - 0.091 12.8 0.1 5.9 7.0 0.0 2.7 3 0 0 3 3 3 0 Mur ligase family, catalytic domain Oligomerisation PF02410.10 EWM26409.1 - 7.3e-25 86.9 0.0 1e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Oligomerisation domain Oligomerisation PF02410.10 EWM26410.1 - 8e-25 86.7 0.0 1.1e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Oligomerisation domain Methyltrans_RNA PF04452.9 EWM26412.1 - 5.5e-41 140.1 0.0 2.7e-39 134.6 0.0 2.2 1 1 0 1 1 1 1 RNA methyltransferase PT PF04886.7 EWM26413.1 - 6.3e-21 73.4 192.2 0.0041 16.3 24.2 7.9 2 1 4 6 6 6 3 PT repeat RNase_PH PF01138.16 EWM26414.1 - 9.3e-23 80.9 0.1 3.1e-22 79.2 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EWM26414.1 - 3e-05 23.8 0.0 4.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 PLDc PF00614.17 EWM26417.1 - 0.0055 16.4 0.4 0.44 10.4 0.0 3.1 3 0 0 3 3 3 2 Phospholipase D Active site motif zf-Sec23_Sec24 PF04810.10 EWM26421.1 - 8.9e-19 66.7 7.9 1.3e-18 66.2 5.5 1.2 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger DUF164 PF02591.10 EWM26421.1 - 0.12 12.2 0.3 0.23 11.3 0.2 1.5 1 0 0 1 1 1 0 Putative zinc ribbon domain zf-MIZ PF02891.15 EWM26421.1 - 2.8 7.5 5.2 2.5 7.6 2.5 1.9 2 1 0 2 2 2 0 MIZ/SP-RING zinc finger GBV-C_env PF12786.2 EWM26422.1 - 0.019 13.4 2.1 0.023 13.1 1.5 1.1 1 0 0 1 1 1 0 GB virus C genotype envelope Phage_mat-A PF03863.8 EWM26422.1 - 0.13 11.3 0.0 0.14 11.2 0.0 1.0 1 0 0 1 1 1 0 Phage maturation protein Sec23_trunk PF04811.10 EWM26425.1 - 2.9e-16 59.5 0.0 3.2e-16 59.4 0.0 1.0 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain FANCI_S1-cap PF14674.1 EWM26425.1 - 0.16 12.0 0.4 0.33 11.0 0.3 1.5 1 0 0 1 1 1 0 FANCI solenoid 1 cap HTH_32 PF13565.1 EWM26426.1 - 3.5 8.4 7.6 2.6 8.8 0.6 2.5 3 0 0 3 3 3 0 Homeodomain-like domain Sec23_helical PF04815.10 EWM26428.1 - 4.3e-29 99.9 0.1 9.5e-29 98.8 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EWM26428.1 - 3.2e-27 94.8 0.0 1e-26 93.2 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Sec23_trunk PF04811.10 EWM26428.1 - 1.1e-26 93.7 0.0 1.6e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Gelsolin PF00626.17 EWM26428.1 - 3.9e-11 42.4 0.0 7.2e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat F_bP_aldolase PF01116.15 EWM26429.1 - 6.4e-72 242.0 0.3 9.9e-72 241.4 0.2 1.2 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DUF1537 PF07005.6 EWM26429.1 - 6.3e-19 68.5 1.6 2.4e-18 66.6 0.1 2.8 2 1 0 2 2 2 1 Protein of unknown function, DUF1537 Thioredoxin PF00085.15 EWM26430.1 - 1e-19 70.1 0.0 1.7e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EWM26430.1 - 9e-07 28.9 0.0 2.2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EWM26430.1 - 5.9e-05 22.7 0.0 9.2e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.1 EWM26430.1 - 0.00049 20.2 0.0 0.001 19.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 EWM26430.1 - 0.0011 18.5 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 EWM26430.1 - 0.0012 18.8 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 EWM26430.1 - 0.015 14.8 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 Redoxin Lipase_3 PF01764.20 EWM26431.1 - 4.6e-35 120.2 0.0 7.5e-35 119.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.17 EWM26431.1 - 0.00084 19.1 0.0 0.012 15.4 0.0 2.2 2 0 0 2 2 2 1 Cutinase DUF2974 PF11187.3 EWM26431.1 - 0.0019 17.5 0.0 0.059 12.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.2 EWM26431.1 - 0.0031 17.4 0.0 0.0055 16.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EWM26431.1 - 0.0043 17.3 0.0 0.0071 16.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.2 EWM26431.1 - 0.035 13.8 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2305 PF10230.4 EWM26431.1 - 0.039 13.3 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_1 PF00561.15 EWM26431.1 - 0.054 13.0 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold EF-hand_1 PF00036.27 EWM26433.1 - 0.0034 16.5 0.2 0.009 15.2 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 EWM26433.1 - 0.0098 15.2 1.1 0.0098 15.2 0.8 1.9 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 EWM26433.1 - 0.037 14.1 0.0 0.073 13.2 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair DUF2781 PF10914.3 EWM26434.1 - 1e-34 119.4 13.5 1.2e-34 119.2 9.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Glycos_transf_1 PF00534.15 EWM26435.1 - 3.1e-16 59.2 0.0 9.1e-16 57.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EWM26435.1 - 2.6e-09 37.3 0.0 5e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EWM26435.1 - 7.9e-06 26.0 0.0 2.2e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EWM26435.1 - 0.02 15.0 0.5 0.053 13.6 0.1 1.9 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain Lipase_GDSL_2 PF13472.1 EWM26439.1 - 2.2e-07 31.1 0.0 2.9e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EWM26439.1 - 5.8e-07 29.5 0.0 7.5e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Ank PF00023.25 EWM26440.1 - 0.005 16.5 0.0 0.015 15.1 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 EWM26440.1 - 0.012 15.9 0.0 0.031 14.5 0.0 1.7 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Coprogen_oxidas PF01218.13 EWM26442.1 - 2.6e-97 324.9 0.0 3.5e-97 324.5 0.0 1.2 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Aa_trans PF01490.13 EWM26445.1 - 2.2e-26 92.3 14.0 1.8e-16 59.6 3.8 2.9 3 0 0 3 3 3 3 Transmembrane amino acid transporter protein VKOR PF07884.9 EWM26445.1 - 0.22 11.3 4.8 4.7 7.0 0.7 2.8 2 1 0 2 2 2 0 Vitamin K epoxide reductase family DHO_dh PF01180.16 EWM26446.1 - 3.1e-98 328.3 0.0 3.7e-98 328.1 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase PcrB PF01884.12 EWM26446.1 - 0.22 10.7 0.2 4.6 6.4 0.0 2.3 2 0 0 2 2 2 0 PcrB family CENP-B_dimeris PF09026.5 EWM26447.1 - 0.036 14.3 1.3 0.077 13.2 0.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Glyco_tranf_2_4 PF13704.1 EWM26448.1 - 1.1e-07 31.9 0.1 1.4e-06 28.5 0.1 2.4 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.22 EWM26448.1 - 7e-06 25.5 0.0 0.00055 19.3 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase family 92 Ribosomal_60s PF00428.14 EWM26450.1 - 5.6e-20 71.5 9.6 7.8e-20 71.0 6.7 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein eIF3_subunit PF08597.5 EWM26450.1 - 0.0086 15.6 0.4 0.012 15.1 0.3 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Aminotran_1_2 PF00155.16 EWM26452.1 - 2.6e-38 131.9 0.0 5.7e-38 130.8 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.8 EWM26452.1 - 5.6e-05 21.9 0.0 0.0082 14.8 0.0 2.3 2 0 0 2 2 2 2 Allinase SPOR PF05036.8 EWM26452.1 - 0.067 13.3 0.0 6.5 6.9 0.0 2.5 2 0 0 2 2 2 0 Sporulation related domain Mito_carr PF00153.22 EWM26453.1 - 6.1e-57 189.3 0.5 1.4e-25 88.8 0.0 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein TrbC PF04956.8 EWM26453.1 - 0.29 11.1 1.9 5.1 7.1 0.3 3.1 3 0 0 3 3 3 0 TrbC/VIRB2 family DUF3586 PF12131.3 EWM26454.1 - 0.00027 20.9 0.1 0.00057 19.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3586) Ribosomal_S8e PF01201.17 EWM26455.1 - 2.9e-38 131.0 7.1 4.4e-37 127.1 4.9 2.2 1 1 0 1 1 1 1 Ribosomal protein S8e Lipase_3 PF01764.20 EWM26457.1 - 5.3e-10 39.0 0.0 1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) adh_short PF00106.20 EWM26458.1 - 5.1e-24 85.0 1.1 9.2e-24 84.2 0.7 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EWM26458.1 - 2.1e-21 76.8 0.0 2.3e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EWM26458.1 - 5.8e-14 52.1 1.3 1.1e-13 51.2 0.9 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EWM26458.1 - 1.1e-05 25.5 0.1 4.8e-05 23.4 0.1 2.0 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EWM26458.1 - 9.5e-05 21.9 0.1 0.00015 21.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ApbA PF02558.11 EWM26458.1 - 9.9e-05 21.8 0.2 0.0023 17.3 0.1 2.3 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 EWM26458.1 - 0.00027 21.3 0.1 0.0039 17.5 0.0 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.8 EWM26458.1 - 0.0029 16.8 0.1 0.0047 16.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EWM26458.1 - 0.02 13.6 0.0 0.029 13.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EWM26458.1 - 0.029 13.2 0.0 0.04 12.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TrkA_N PF02254.13 EWM26458.1 - 0.03 14.3 0.1 0.079 12.9 0.1 1.8 1 1 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.15 EWM26458.1 - 0.091 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 EWM26458.1 - 0.11 12.1 0.1 0.51 10.0 0.0 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus RVT_2 PF07727.9 EWM26459.1 - 1.5e-84 282.7 0.0 2.3e-84 282.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EWM26459.1 - 5.3e-11 42.6 0.1 2e-10 40.8 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 EWM26459.1 - 0.021 14.3 0.0 0.052 13.0 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Cas_Csa5 PF09702.5 EWM26459.1 - 0.095 12.7 0.1 1.4 9.0 0.0 2.6 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csa5) PSII_BNR PF14870.1 EWM26464.1 - 0.017 14.1 2.4 0.021 13.8 1.7 1.1 1 0 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 BNR PF02012.15 EWM26464.1 - 0.032 14.0 14.7 0.3 11.0 0.6 3.8 3 1 1 4 4 4 0 BNR/Asp-box repeat BNR_3 PF13859.1 EWM26464.1 - 3.2 6.7 7.9 2.4 7.1 0.6 2.1 1 1 1 2 2 2 0 BNR repeat-like domain Herpeto_peptide PF14409.1 EWM26467.1 - 0.077 12.7 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Herpetosiphon DUF423 PF04241.10 EWM26468.1 - 2.7e-19 68.8 3.1 1.4e-18 66.5 2.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF423) YiaAB PF05360.9 EWM26468.1 - 0.14 11.7 0.3 0.14 11.7 0.2 2.3 2 0 0 2 2 2 0 yiaA/B two helix domain DUF202 PF02656.10 EWM26468.1 - 0.89 9.8 5.4 1.4 9.1 1.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF4345 PF14248.1 EWM26468.1 - 0.99 8.8 6.3 10 5.6 4.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4345) DNA_pol_B_thumb PF14791.1 EWM26472.1 - 2.2e-18 65.7 0.0 5.1e-18 64.5 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 EWM26472.1 - 6.9e-10 38.9 1.7 9e-08 32.1 0.0 2.6 1 1 1 2 2 2 2 DNA polymerase beta palm HHH_8 PF14716.1 EWM26472.1 - 2.2e-05 24.5 0.0 5.6e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 EWM26472.1 - 0.00031 20.2 0.0 0.00068 19.1 0.0 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda Nramp PF01566.13 EWM26474.1 - 3.3e-120 401.1 22.5 5e-120 400.5 15.6 1.3 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Carb_kinase PF01256.12 EWM26476.1 - 2.5e-38 131.7 0.2 2e-36 125.5 0.2 2.9 1 1 0 1 1 1 1 Carbohydrate kinase DDHD PF02862.12 EWM26478.1 - 7.1e-39 133.9 1.9 2.8e-38 131.9 0.0 2.3 2 1 0 2 2 2 1 DDHD domain DUF676 PF05057.9 EWM26478.1 - 0.00061 19.1 0.0 0.042 13.1 0.0 2.2 2 0 0 2 2 2 1 Putative serine esterase (DUF676) WWE PF02825.15 EWM26478.1 - 0.0021 17.4 0.0 0.36 10.2 0.0 2.4 2 0 0 2 2 2 2 WWE domain Abhydrolase_5 PF12695.2 EWM26478.1 - 0.019 14.7 0.0 0.055 13.2 0.0 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3089 PF11288.3 EWM26478.1 - 0.042 13.0 0.0 0.12 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) LCAT PF02450.10 EWM26478.1 - 0.26 10.1 0.0 0.45 9.4 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Pkinase PF00069.20 EWM26479.1 - 1.9e-53 181.2 0.0 3e-48 164.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EWM26479.1 - 9.5e-33 113.3 0.0 7e-30 103.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EWM26479.1 - 0.0021 17.0 0.0 0.0036 16.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 EWM26480.1 - 4.3e-51 173.5 0.0 4.1e-46 157.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EWM26480.1 - 5.8e-32 110.7 0.0 2.9e-30 105.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EWM26480.1 - 5.9e-05 22.1 0.0 0.00021 20.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Nup_retrotrp_bd PF10599.4 EWM26482.1 - 0.024 15.2 0.0 10 6.8 0.0 2.3 2 0 0 2 2 2 0 Retro-transposon transporting motif Synapsin_N PF10581.4 EWM26482.1 - 8 6.3 5.9 37 4.2 0.1 3.1 3 0 0 3 3 3 0 Synapsin N-terminal U3_assoc_6 PF08640.6 EWM26483.1 - 7.2e-23 80.1 0.2 7.2e-23 80.1 0.2 1.8 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 DUF3046 PF11248.3 EWM26483.1 - 0.012 15.5 0.1 0.079 12.9 0.1 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3046) BNR PF02012.15 EWM26484.1 - 0.0022 17.5 12.8 0.15 11.9 0.8 3.7 3 0 0 3 3 3 2 BNR/Asp-box repeat AAA PF00004.24 EWM26487.1 - 1.2e-98 326.4 0.0 3.5e-48 163.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EWM26487.1 - 5.8e-21 74.2 1.5 1e-20 73.4 0.4 2.0 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 EWM26487.1 - 1.3e-13 50.5 0.0 1.1e-05 24.6 0.0 3.1 3 1 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus CDC48_2 PF02933.12 EWM26487.1 - 1.8e-13 49.9 0.0 4.4e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 EWM26487.1 - 3.9e-13 49.6 0.5 3.5e-05 23.9 0.0 4.8 4 2 0 4 4 2 2 AAA domain AAA_2 PF07724.9 EWM26487.1 - 1.7e-12 47.6 0.0 3.7e-06 26.9 0.0 3.0 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EWM26487.1 - 3.4e-12 46.7 0.0 4.3e-05 23.5 0.0 3.5 2 2 1 3 3 3 2 AAA ATPase domain AAA_33 PF13671.1 EWM26487.1 - 1.2e-11 44.6 0.0 1.5e-05 24.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EWM26487.1 - 1.2e-11 45.4 0.0 2.2e-05 25.2 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EWM26487.1 - 2.4e-11 43.5 0.1 7.4e-06 25.7 0.0 3.6 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EWM26487.1 - 2.4e-09 37.1 0.0 0.00036 20.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EWM26487.1 - 4.1e-08 32.5 0.0 0.0023 17.0 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin TIP49 PF06068.8 EWM26487.1 - 4.5e-08 32.2 0.0 0.00062 18.5 0.0 2.6 2 0 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 EWM26487.1 - 4.1e-07 29.5 2.1 0.34 10.2 0.0 4.2 2 2 2 4 4 4 2 AAA domain RNA_helicase PF00910.17 EWM26487.1 - 1.3e-06 28.5 0.0 0.019 15.1 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_19 PF13245.1 EWM26487.1 - 1.3e-06 28.0 0.9 0.024 14.3 0.3 2.9 2 0 0 2 2 2 2 Part of AAA domain Mg_chelatase PF01078.16 EWM26487.1 - 1.3e-06 27.7 0.2 0.057 12.5 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EWM26487.1 - 1.3e-06 28.7 0.1 0.018 15.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.12 EWM26487.1 - 1.8e-06 27.4 0.0 0.089 12.2 0.0 2.9 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 EWM26487.1 - 2.5e-06 27.5 0.0 0.024 14.6 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 EWM26487.1 - 3.2e-06 27.0 0.1 0.085 12.5 0.1 3.6 2 2 2 4 4 4 2 Archaeal ATPase KaiC PF06745.8 EWM26487.1 - 6.2e-06 25.4 0.3 1.1 8.2 0.0 3.5 2 1 1 3 3 3 2 KaiC AAA_28 PF13521.1 EWM26487.1 - 9.8e-06 25.6 0.2 0.34 10.8 0.0 3.2 3 0 0 3 3 3 2 AAA domain NACHT PF05729.7 EWM26487.1 - 1.1e-05 25.1 0.0 1.9 8.1 0.0 4.2 3 1 1 4 4 4 2 NACHT domain ResIII PF04851.10 EWM26487.1 - 1.4e-05 25.0 0.0 0.0036 17.1 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 EWM26487.1 - 2.8e-05 23.7 0.0 0.018 14.5 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Vps4_C PF09336.5 EWM26487.1 - 2.8e-05 23.8 0.0 0.00018 21.3 0.0 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain ABC_tran PF00005.22 EWM26487.1 - 4.1e-05 23.8 0.2 0.33 11.2 0.0 3.6 4 1 0 4 4 2 2 ABC transporter AAA_24 PF13479.1 EWM26487.1 - 0.00012 21.7 0.0 0.59 9.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 EWM26487.1 - 0.00013 20.9 0.0 0.4 9.4 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain Cytidylate_kin2 PF13189.1 EWM26487.1 - 0.00013 21.8 1.0 0.057 13.3 0.0 2.8 3 0 0 3 3 3 1 Cytidylate kinase-like family Sigma54_activat PF00158.21 EWM26487.1 - 0.00014 21.3 0.0 0.47 9.8 0.0 3.2 2 2 0 2 2 2 1 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EWM26487.1 - 0.00021 20.2 0.0 0.34 9.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.13 EWM26487.1 - 0.00048 19.8 0.0 0.47 10.0 0.0 2.7 3 0 0 3 3 2 1 Bacterial dnaA protein NTPase_1 PF03266.10 EWM26487.1 - 0.0012 18.5 0.6 1.4 8.5 0.0 4.0 3 1 1 4 4 3 1 NTPase DUF815 PF05673.8 EWM26487.1 - 0.0012 17.7 0.0 0.29 10.0 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_3 PF07726.6 EWM26487.1 - 0.0015 18.1 0.0 1.6 8.3 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EWM26487.1 - 0.0018 17.9 0.0 0.79 9.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 EWM26487.1 - 0.0029 16.8 0.1 2.5 7.2 0.0 2.7 2 0 0 2 2 2 1 PhoH-like protein SKI PF01202.17 EWM26487.1 - 0.0048 16.7 0.6 3.8 7.3 0.0 3.0 3 0 0 3 3 2 0 Shikimate kinase DUF2075 PF09848.4 EWM26487.1 - 0.0078 15.2 0.0 1.1 8.1 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UFD1 PF03152.9 EWM26487.1 - 0.0082 15.2 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 AAA_10 PF12846.2 EWM26487.1 - 0.009 15.4 0.4 28 3.9 0.0 3.9 3 1 1 4 4 4 0 AAA-like domain Molydop_binding PF01568.16 EWM26487.1 - 0.014 15.2 0.0 0.038 13.8 0.0 1.8 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain AAA_11 PF13086.1 EWM26487.1 - 0.029 13.9 0.1 11 5.5 0.0 3.0 2 1 0 2 2 2 0 AAA domain Zot PF05707.7 EWM26487.1 - 0.045 13.2 0.2 4.7 6.6 0.1 3.2 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) UPF0079 PF02367.12 EWM26487.1 - 0.05 13.2 0.1 5.9 6.5 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 KTI12 PF08433.5 EWM26487.1 - 0.055 12.6 0.0 9.7 5.3 0.0 2.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 KAP_NTPase PF07693.9 EWM26487.1 - 0.073 12.0 0.2 2.7 6.9 0.0 3.0 2 2 2 4 4 4 0 KAP family P-loop domain DUF4637 PF15470.1 EWM26487.1 - 0.086 12.4 1.4 0.17 11.4 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) AAA_23 PF13476.1 EWM26487.1 - 0.13 12.5 0.0 10 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EWM26487.1 - 0.15 11.6 0.0 6.9 6.2 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Rad17 PF03215.10 EWM26487.1 - 0.19 10.3 0.0 2.6 6.6 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein APC8 PF04049.8 EWM26488.1 - 5.5e-25 87.7 0.0 1.7e-24 86.1 0.0 1.9 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 EWM26488.1 - 6.2e-25 85.7 24.0 7.4e-06 25.3 0.3 7.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.1 EWM26488.1 - 4.5e-21 74.2 23.7 9e-11 41.2 0.7 6.2 3 1 4 7 7 7 5 TPR repeat TPR_2 PF07719.12 EWM26488.1 - 8.3e-19 65.9 36.8 5.7e-05 22.7 0.2 9.4 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_8 PF13181.1 EWM26488.1 - 2.5e-15 55.0 9.2 0.0017 18.0 0.0 5.9 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 EWM26488.1 - 8.4e-13 48.4 12.5 0.0017 18.6 0.3 7.0 6 1 1 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 EWM26488.1 - 1.3e-11 44.4 20.2 3.3e-05 23.9 1.9 6.0 4 1 3 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EWM26488.1 - 6.5e-11 42.0 33.3 7.7e-05 22.5 1.3 6.5 5 1 3 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.1 EWM26488.1 - 1.2e-10 40.3 27.2 0.00087 18.9 0.1 7.6 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 EWM26488.1 - 4.8e-09 35.7 15.1 0.002 18.1 0.3 6.7 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 EWM26488.1 - 5.1e-09 35.9 37.0 0.00025 21.4 0.0 10.2 7 3 4 11 11 10 2 Tetratricopeptide repeat TPR_16 PF13432.1 EWM26488.1 - 6e-07 29.9 0.8 6e-07 29.9 0.5 9.4 5 2 4 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.1 EWM26488.1 - 0.0016 18.2 25.8 0.026 14.3 0.7 5.0 5 1 0 6 6 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EWM26488.1 - 0.0049 17.2 25.9 6 7.5 0.0 9.1 10 0 0 10 10 8 1 Tetratricopeptide repeat ChAPs PF09295.5 EWM26488.1 - 0.1 11.3 0.0 0.42 9.3 0.0 1.9 2 1 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.1 EWM26488.1 - 0.19 11.6 0.0 0.19 11.6 0.0 6.8 8 1 1 9 9 8 0 Tetratricopeptide repeat Asp_protease PF09668.5 EWM26489.1 - 1.3e-19 69.9 0.7 2e-19 69.4 0.5 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EWM26489.1 - 4.5e-07 29.5 0.6 1.6e-06 27.8 0.1 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EWM26489.1 - 3.7e-06 27.3 0.0 9.8e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EWM26489.1 - 0.087 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Yae1_N PF09811.4 EWM26489.1 - 7.7 6.1 10.6 0.15 11.6 0.4 2.9 3 0 0 3 3 3 0 Essential protein Yae1, N terminal Cellulase PF00150.13 EWM26490.1 - 1.1e-40 139.5 1.2 1.4e-40 139.2 0.8 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) U-box PF04564.10 EWM26492.1 - 9.6e-07 28.6 0.0 1.1e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.3 EWM26492.1 - 0.00076 18.9 0.0 0.00089 18.7 0.0 1.2 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Rtf2 PF04641.7 EWM26492.1 - 0.0068 15.6 0.0 0.0071 15.5 0.0 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger GST_N_3 PF13417.1 EWM26492.1 - 0.027 14.6 0.0 0.044 14.0 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Amino_oxidase PF01593.19 EWM26493.1 - 5.4e-41 141.1 0.0 7e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EWM26493.1 - 1.4e-09 37.8 0.0 3.3e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EWM26493.1 - 1.2e-06 27.6 0.0 1.8e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EWM26493.1 - 2.6e-05 23.4 0.1 4.4e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EWM26493.1 - 0.00013 20.9 0.0 0.00023 20.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EWM26493.1 - 0.00027 20.1 0.0 0.00039 19.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EWM26493.1 - 0.00036 19.6 0.0 0.00054 19.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EWM26493.1 - 0.023 14.5 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EWM26493.1 - 0.089 11.6 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Methyltransf_26 PF13659.1 EWM26494.1 - 1.8e-11 44.0 0.0 2.6e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EWM26494.1 - 4.1e-07 29.5 0.0 4.9e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EWM26494.1 - 0.00017 21.2 0.0 0.00023 20.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM26494.1 - 0.0019 18.5 0.0 0.0031 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EWM26494.1 - 0.066 12.7 0.0 0.12 11.9 0.0 1.4 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Aa_trans PF01490.13 EWM26496.1 - 6.2e-13 48.0 7.2 7.3e-13 47.7 5.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ribosomal_L31e PF01198.14 EWM26499.1 - 7.6e-36 121.6 3.2 9.6e-36 121.3 2.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e SBDS_C PF09377.5 EWM26499.1 - 0.039 13.6 0.0 0.044 13.4 0.0 1.1 1 0 0 1 1 1 0 SBDS protein C-terminal domain MFS_1 PF07690.11 EWM26500.1 - 6.3e-06 25.1 0.6 8.1e-06 24.7 0.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 EWM26501.1 - 0.051 12.2 7.7 0.03 13.0 2.5 2.0 2 0 0 2 2 2 0 Major Facilitator Superfamily Pkinase_Tyr PF07714.12 EWM26502.1 - 2.9e-18 65.8 0.1 3.1e-18 65.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EWM26502.1 - 1.3e-16 60.5 0.0 1.4e-16 60.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pheromone PF08015.6 EWM26503.1 - 0.34 11.7 8.1 0.17 12.7 0.8 2.6 1 1 1 2 2 2 0 Fungal mating-type pheromone Tim54 PF11711.3 EWM26505.1 - 0.091 11.3 1.0 0.1 11.1 0.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 peroxidase PF00141.18 EWM26506.1 - 3.9e-05 23.2 0.0 5e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Peroxidase peroxidase PF00141.18 EWM26509.1 - 2.6e-14 53.2 0.0 3.5e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Peroxidase Glyco_hydro_38C PF07748.8 EWM26511.1 - 1.1e-11 44.3 0.0 1.4e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Glyco_hydro_38 PF01074.17 EWM26513.1 - 2.8e-06 26.7 0.5 3.3e-06 26.5 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Prp18 PF02840.10 EWM26514.1 - 8.4e-45 152.1 0.1 9.4e-45 151.9 0.1 1.0 1 0 0 1 1 1 1 Prp18 domain PRP4 PF08799.6 EWM26515.1 - 8.7e-10 37.7 0.3 8.7e-10 37.7 0.2 2.8 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like Borealin PF10512.4 EWM26517.1 - 1.1e-08 34.9 1.0 2.7e-08 33.7 0.7 1.6 1 0 0 1 1 1 1 Cell division cycle-associated protein 8 Nbl1_Borealin_N PF10444.4 EWM26517.1 - 5.8e-08 31.9 1.4 9.5e-08 31.2 1.0 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal DHDPS PF00701.17 EWM26517.1 - 0.03 12.9 0.1 0.069 11.7 0.0 1.5 2 0 0 2 2 2 0 Dihydrodipicolinate synthetase family Ribosomal_L19e PF01280.15 EWM26517.1 - 0.74 9.5 6.4 1.6 8.4 4.4 1.5 1 0 0 1 1 1 0 Ribosomal protein L19e Myb_DNA-binding PF00249.26 EWM26518.1 - 9.8e-05 22.3 0.0 0.00025 21.0 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Cullin PF00888.17 EWM26520.1 - 1.8e-32 112.6 0.1 2.5e-32 112.2 0.1 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EWM26520.1 - 3.2e-26 90.9 0.9 6e-26 90.0 0.6 1.5 1 0 0 1 1 1 1 Cullin protein neddylation domain Cullin PF00888.17 EWM26521.1 - 2.8e-19 69.1 0.0 3e-19 68.9 0.0 1.0 1 0 0 1 1 1 1 Cullin family Cullin PF00888.17 EWM26522.1 - 8.3e-26 90.6 0.2 9.3e-26 90.5 0.1 1.0 1 0 0 1 1 1 1 Cullin family PHD PF00628.24 EWM26523.1 - 2.7e-10 39.7 7.2 6e-10 38.6 5.0 1.6 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 EWM26523.1 - 1.8e-09 37.8 8.2 9.8e-07 29.0 2.9 2.5 2 1 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding zf-RING-like PF08746.6 EWM26523.1 - 0.043 13.8 6.0 0.11 12.5 4.2 1.7 1 0 0 1 1 1 0 RING-like domain MIP-T3 PF10243.4 EWM26523.1 - 0.21 10.0 32.5 0.3 9.5 22.5 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PHD_2 PF13831.1 EWM26523.1 - 0.34 10.2 3.0 1 8.7 2.1 1.8 1 0 0 1 1 1 0 PHD-finger Allantoicase PF03561.10 EWM26524.1 - 7.4e-92 304.7 0.0 4.5e-51 172.3 0.0 2.4 2 1 0 2 2 2 2 Allantoicase repeat Allantoicase PF03561.10 EWM26525.1 - 7.4e-92 304.7 0.0 4.5e-51 172.3 0.0 2.4 2 1 0 2 2 2 2 Allantoicase repeat Endonuclease_5 PF04493.9 EWM26526.1 - 4.3e-52 176.4 0.0 6.8e-40 136.6 0.0 2.1 2 0 0 2 2 2 2 Endonuclease V Pro_dh PF01619.13 EWM26527.1 - 1.4e-66 224.6 0.3 2.2e-66 223.9 0.2 1.2 1 0 0 1 1 1 1 Proline dehydrogenase EF-hand_8 PF13833.1 EWM26527.1 - 1.6e-05 24.3 0.1 0.007 15.9 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.1 EWM26527.1 - 0.00013 22.0 0.0 0.00039 20.5 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EWM26527.1 - 0.00048 19.2 0.8 0.0076 15.4 0.3 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EWM26527.1 - 0.0013 18.4 0.9 0.017 14.9 0.2 2.5 2 0 0 2 2 2 1 EF-hand domain eIF-5_eIF-2B PF01873.12 EWM26528.1 - 1.9e-36 124.4 0.0 3e-36 123.8 0.0 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.1 EWM26528.1 - 0.012 15.8 0.1 0.03 14.6 0.1 1.7 1 0 0 1 1 1 0 Restriction alleviation protein Lar Ycf1 PF05758.7 EWM26528.1 - 9.7 3.7 6.7 5 4.7 2.6 1.7 2 0 0 2 2 2 0 Ycf1 Cullin PF00888.17 EWM26529.1 - 2.1e-13 49.7 1.4 2.3e-13 49.5 1.0 1.0 1 0 0 1 1 1 1 Cullin family Herpes_glycop_H PF02489.11 EWM26529.1 - 0.045 11.7 0.0 0.046 11.7 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein H Tn7_Tnp_TnsA_N PF08722.6 EWM26529.1 - 0.049 13.6 0.2 0.097 12.6 0.1 1.5 1 1 0 1 1 1 0 TnsA endonuclease N terminal DUF3885 PF13021.1 EWM26529.1 - 0.31 10.7 0.0 0.31 10.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3885) GST_N_3 PF13417.1 EWM26530.1 - 5.6e-23 80.9 0.0 1.4e-10 41.2 0.0 2.3 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EWM26530.1 - 1.3e-11 44.3 0.0 1.5e-05 24.8 0.0 2.3 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 EWM26530.1 - 1.4e-05 25.0 0.1 0.0055 16.6 0.0 2.5 2 0 0 2 2 2 2 Glutaredoxin GST_N PF02798.15 EWM26530.1 - 0.0011 19.1 0.0 0.39 10.9 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EWM26531.1 - 1.3e-18 66.9 0.0 2.8e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EWM26531.1 - 1.3e-12 47.4 0.0 2.4e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EWM26531.1 - 3.3e-10 39.9 0.0 6.4e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EWM26531.1 - 3.1e-07 30.1 0.7 8.2e-07 28.8 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EWM26531.1 - 0.028 14.4 0.0 0.063 13.2 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin GST_C_3 PF14497.1 EWM26531.1 - 0.055 13.9 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PAP_central PF04928.12 EWM26533.1 - 6e-66 221.8 0.0 1.1e-65 220.9 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EWM26533.1 - 6.8e-16 58.1 0.0 1.5e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EWM26533.1 - 3.3e-05 24.1 0.0 7.6e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Ank PF00023.25 EWM26533.1 - 0.00091 18.9 0.0 0.003 17.2 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 EWM26533.1 - 0.009 16.3 0.0 0.048 14.0 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) DUF4269 PF14091.1 EWM26533.1 - 0.015 15.2 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) Ank_5 PF13857.1 EWM26533.1 - 0.016 15.4 0.0 0.088 13.0 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_4 PF13637.1 EWM26533.1 - 0.088 13.3 0.0 0.92 10.0 0.0 2.2 1 1 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM26533.1 - 0.11 12.8 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat TPR_7 PF13176.1 EWM26535.1 - 0.34 10.8 1.6 3.9 7.5 0.2 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat SLX9 PF15341.1 EWM26535.1 - 0.69 10.3 3.8 1.5 9.3 2.7 1.6 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 DUF1049 PF06305.6 EWM26535.1 - 0.7 9.4 6.3 0.27 10.7 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) IncA PF04156.9 EWM26535.1 - 0.73 9.3 8.0 1.5 8.4 5.6 1.4 1 1 0 1 1 1 0 IncA protein RNA_pol_N PF01194.12 EWM26536.1 - 7.3e-29 99.5 1.1 1.1e-28 99.0 0.8 1.3 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Yippee-Mis18 PF03226.9 EWM26536.1 - 0.12 12.4 0.4 0.17 11.9 0.2 1.5 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Chordopox_RPO7 PF05864.7 EWM26536.1 - 0.23 11.5 4.1 0.087 12.9 0.7 1.9 2 1 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) PPR_2 PF13041.1 EWM26537.1 - 9.9e-26 89.4 0.0 7.5e-07 29.0 0.0 5.4 3 1 2 5 5 5 5 PPR repeat family PPR_3 PF13812.1 EWM26537.1 - 1.4e-19 68.6 4.6 0.0085 16.2 0.0 8.1 10 0 0 10 10 10 4 Pentatricopeptide repeat domain PPR PF01535.15 EWM26537.1 - 5e-19 66.8 4.1 0.0097 15.8 0.0 7.1 7 0 0 7 7 7 5 PPR repeat PPR_1 PF12854.2 EWM26537.1 - 5.8e-07 28.8 0.1 1.1 8.7 0.0 5.9 6 0 0 6 6 6 2 PPR repeat PaREP1 PF05942.6 EWM26537.1 - 1.8 8.4 8.2 11 5.8 0.7 3.7 4 0 0 4 4 4 0 Archaeal PaREP1/PaREP8 family PBP1_TM PF14812.1 EWM26538.1 - 0.31 11.3 5.4 0.46 10.8 3.7 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2201_N PF13203.1 EWM26538.1 - 0.33 10.0 4.5 0.37 9.9 3.1 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain BLVR PF06375.6 EWM26538.1 - 0.33 10.7 2.7 0.44 10.3 1.8 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) BSP_II PF05432.6 EWM26538.1 - 0.38 9.9 9.5 0.44 9.7 6.6 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CobT PF06213.7 EWM26538.1 - 1.1 8.3 6.8 1.3 8.1 4.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF3306 PF11748.3 EWM26538.1 - 2.7 8.6 7.0 3 8.5 4.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3306) Daxx PF03344.10 EWM26538.1 - 8.8 4.6 6.7 8.9 4.6 4.7 1.0 1 0 0 1 1 1 0 Daxx Family Mem_trans PF03547.13 EWM26539.1 - 1.1e-24 86.4 14.6 6.1e-16 57.7 0.1 2.1 1 1 1 2 2 2 2 Membrane transport protein SBF PF01758.11 EWM26539.1 - 0.015 14.6 8.4 0.044 13.1 5.8 1.7 1 0 0 1 1 1 0 Sodium Bile acid symporter family Mem_trans PF03547.13 EWM26540.1 - 8.2e-25 86.8 14.5 5.3e-16 57.8 0.0 2.1 1 1 1 2 2 2 2 Membrane transport protein SBF PF01758.11 EWM26540.1 - 0.014 14.7 8.4 0.04 13.3 5.8 1.7 1 0 0 1 1 1 0 Sodium Bile acid symporter family Gamma-thionin PF00304.15 EWM26542.1 - 0.04 13.9 1.3 0.063 13.3 0.3 1.7 2 0 0 2 2 2 0 Gamma-thionin family LELP1 PF15042.1 EWM26542.1 - 2.6 8.2 16.1 3.3 7.9 11.2 1.2 1 0 0 1 1 1 0 Late cornified envelope-like proline-rich protein 1 AAA PF00004.24 EWM26544.1 - 1e-41 142.2 0.0 1.9e-41 141.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EWM26544.1 - 1.9e-06 28.6 0.0 4.4e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EWM26544.1 - 2e-06 27.9 0.2 0.019 15.1 0.0 2.7 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 EWM26544.1 - 8.9e-06 25.8 1.8 0.00094 19.2 0.1 3.0 2 1 1 3 3 2 1 AAA ATPase domain TIP49 PF06068.8 EWM26544.1 - 2.5e-05 23.1 0.0 4.2e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 EWM26544.1 - 4.1e-05 23.3 0.0 0.00015 21.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EWM26544.1 - 6.2e-05 23.0 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EWM26544.1 - 0.00018 21.4 0.0 0.00041 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EWM26544.1 - 0.00042 19.7 0.0 0.00071 19.0 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 EWM26544.1 - 0.00043 19.4 0.0 0.00089 18.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 EWM26544.1 - 0.00048 20.4 0.0 0.0011 19.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EWM26544.1 - 0.00056 19.5 0.1 0.002 17.8 0.1 2.0 2 0 0 2 2 1 1 Part of AAA domain AAA_33 PF13671.1 EWM26544.1 - 0.0028 17.5 0.0 0.0058 16.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EWM26544.1 - 0.0045 16.3 0.8 0.038 13.3 0.3 2.2 1 1 1 2 2 2 1 AAA domain AAA_11 PF13086.1 EWM26544.1 - 0.0059 16.2 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EWM26544.1 - 0.0061 15.6 0.3 0.011 14.8 0.2 1.3 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 EWM26544.1 - 0.0072 15.5 0.2 0.019 14.1 0.1 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EWM26544.1 - 0.0084 16.0 0.0 0.029 14.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EWM26544.1 - 0.018 14.7 0.2 0.11 12.1 0.1 2.3 1 1 0 1 1 1 0 NACHT domain FtsH_ext PF06480.10 EWM26544.1 - 0.02 15.0 0.0 0.064 13.4 0.0 1.8 1 1 0 1 1 1 0 FtsH Extracellular Sigma54_activ_2 PF14532.1 EWM26544.1 - 0.026 14.5 0.0 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 EWM26544.1 - 0.081 12.3 0.0 0.42 10.0 0.0 2.0 1 1 1 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.11 EWM26544.1 - 0.12 11.5 0.1 0.22 10.7 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein DUF815 PF05673.8 EWM26544.1 - 0.12 11.2 0.0 0.43 9.4 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 EWM26544.1 - 0.21 11.8 0.0 0.44 10.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Pkinase PF00069.20 EWM26545.1 - 3e-50 170.8 0.0 3.5e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM26545.1 - 4.3e-21 75.1 0.0 5.9e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EWM26545.1 - 3.6e-05 22.8 0.0 5e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EWM26545.1 - 0.014 15.1 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EWM26545.1 - 0.054 12.8 0.0 0.09 12.1 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL LCE PF14672.1 EWM26546.1 - 0.039 14.4 1.7 0.039 14.4 1.2 2.3 2 0 0 2 2 2 0 Late cornified envelope Proteasome PF00227.21 EWM26547.1 - 7.5e-58 194.9 0.0 8.8e-58 194.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EWM26547.1 - 2.3e-09 36.3 2.3 2.4e-09 36.3 0.1 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RecA PF00154.16 EWM26547.1 - 0.08 11.9 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein DUF605 PF04652.11 EWM26548.1 - 2.1 7.6 9.9 2.5 7.3 6.9 1.0 1 0 0 1 1 1 0 Vta1 like Myb_DNA-binding PF00249.26 EWM26549.1 - 8.2e-36 121.8 9.6 9e-12 44.8 0.2 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EWM26549.1 - 6.7e-15 54.9 7.0 0.00029 20.8 0.1 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain RRM_1 PF00076.17 EWM26550.1 - 4.2e-05 23.0 0.0 0.0072 15.9 0.0 2.7 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM26550.1 - 0.11 12.4 0.0 0.29 11.1 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SMC_N PF02463.14 EWM26551.1 - 1.1e-26 93.4 0.0 5.7e-12 45.3 0.0 2.9 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EWM26551.1 - 4.3e-09 36.9 30.4 4.3e-09 36.9 21.1 5.8 3 2 0 3 3 1 1 AAA domain AAA_15 PF13175.1 EWM26551.1 - 4.5e-06 25.9 4.4 0.0055 15.8 2.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 EWM26551.1 - 1.5e-05 25.1 0.1 0.04 13.8 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EWM26551.1 - 0.00018 20.9 0.0 0.00053 19.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EWM26551.1 - 0.00093 19.0 0.1 0.0033 17.2 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Reo_sigmaC PF04582.7 EWM26551.1 - 0.013 14.6 11.5 0.018 14.2 1.1 3.5 3 1 0 4 4 4 0 Reovirus sigma C capsid protein Adeno_PIX PF03955.9 EWM26551.1 - 0.022 15.2 0.0 0.022 15.2 0.0 6.3 4 2 3 7 7 7 0 Adenovirus hexon-associated protein (IX) AAA_13 PF13166.1 EWM26551.1 - 0.069 11.5 0.0 0.069 11.5 0.0 5.5 5 1 1 6 6 5 0 AAA domain ABC_tran PF00005.22 EWM26551.1 - 0.93 9.7 0.0 0.93 9.7 0.0 5.0 4 1 1 5 5 5 0 ABC transporter NPV_P10 PF05531.7 EWM26551.1 - 2.8 8.2 21.7 0.17 12.1 1.5 5.8 4 1 2 6 6 6 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 EWM26551.1 - 7.2 6.4 7.8 0.56 10.0 0.4 2.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA PF00004.24 EWM26552.1 - 5.6e-35 120.4 0.0 1.4e-34 119.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EWM26552.1 - 6.2e-06 26.1 3.1 9.1e-06 25.5 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EWM26552.1 - 1.4e-05 25.2 0.5 0.0097 16.0 0.0 3.4 1 1 2 3 3 3 1 AAA domain AAA_11 PF13086.1 EWM26552.1 - 1.9e-05 24.3 0.1 0.0056 16.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EWM26552.1 - 2.2e-05 25.2 0.0 5.5e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EWM26552.1 - 0.00013 21.0 0.1 0.00046 19.3 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EWM26552.1 - 0.0003 20.5 0.5 0.0034 17.1 0.4 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EWM26552.1 - 0.00053 19.2 0.1 0.0015 17.6 0.1 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EWM26552.1 - 0.00093 18.6 3.0 0.0014 18.0 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.9 EWM26552.1 - 0.0018 18.2 0.0 0.0018 18.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 EWM26552.1 - 0.0048 16.3 0.7 0.16 11.3 0.2 2.6 1 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EWM26552.1 - 0.0068 16.3 0.0 0.0068 16.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.1 EWM26552.1 - 0.0093 15.5 0.1 0.0093 15.5 0.1 2.4 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EWM26552.1 - 0.011 15.4 2.4 0.041 13.6 0.7 2.6 2 0 0 2 2 2 0 Part of AAA domain TIP49 PF06068.8 EWM26552.1 - 0.017 13.8 0.1 0.028 13.1 0.1 1.2 1 0 0 1 1 1 0 TIP49 C-terminus PhoH PF02562.11 EWM26552.1 - 0.019 14.2 0.0 0.043 13.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_23 PF13476.1 EWM26552.1 - 0.021 15.1 6.1 0.48 10.7 1.8 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EWM26552.1 - 0.022 15.0 0.1 0.064 13.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EWM26552.1 - 0.077 13.1 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Ndc1_Nup PF09531.5 EWM26552.1 - 0.53 8.6 5.1 0.81 8.0 3.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Suf PF05843.9 EWM26552.1 - 1.4 8.6 8.6 2.5 7.7 6.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TSP9 PF11493.3 EWM26552.1 - 2.9 8.4 7.5 4.4 7.9 3.4 2.5 2 0 0 2 2 2 0 Thylakoid soluble phosphoprotein TSP9 S-AdoMet_synt_C PF02773.11 EWM26553.1 - 3.4e-71 237.3 0.5 9.5e-71 235.9 0.1 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EWM26553.1 - 1.6e-49 166.8 0.0 3e-49 165.9 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EWM26553.1 - 1.2e-41 140.9 0.5 2.3e-41 140.0 0.3 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain HSP70 PF00012.15 EWM26556.1 - 1.3e-255 848.9 10.1 1.7e-255 848.6 7.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EWM26556.1 - 6.5e-17 61.1 0.2 1.5e-15 56.6 0.2 2.3 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 EWM26556.1 - 0.0014 17.8 3.4 0.083 11.9 0.0 3.6 3 1 1 4 4 4 1 Hydantoinase/oxoprolinase FtsA PF14450.1 EWM26556.1 - 0.029 14.1 2.5 0.56 10.0 0.4 3.7 2 1 0 2 2 2 0 Cell division protein FtsA StbA PF06406.6 EWM26556.1 - 0.045 12.6 0.1 0.091 11.6 0.0 1.5 1 0 0 1 1 1 0 StbA protein FGGY_C PF02782.11 EWM26556.1 - 0.062 12.9 0.0 0.3 10.6 0.0 2.1 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Rhodanese PF00581.15 EWM26557.1 - 1.6e-30 105.7 0.0 8.5e-16 58.3 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain cNMP_binding PF00027.24 EWM26558.1 - 1.5e-09 37.4 0.0 4.7e-08 32.7 0.0 3.1 2 1 1 3 3 3 1 Cyclic nucleotide-binding domain STAS PF01740.16 EWM26558.1 - 0.0001 21.7 0.1 0.0013 18.1 0.0 2.5 2 1 0 2 2 2 1 STAS domain Sulfate_transp PF00916.15 EWM26558.1 - 0.005 15.8 1.8 0.015 14.2 0.0 2.1 1 1 0 2 2 2 1 Sulfate transporter family Oxidored_FMN PF00724.15 EWM26559.1 - 4.2e-79 266.0 0.0 5.4e-79 265.6 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.9 EWM26559.1 - 4.6e-14 52.7 0.6 5.1e-13 49.3 0.3 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EWM26559.1 - 2.3e-13 50.6 0.1 3.7e-05 23.8 0.1 3.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EWM26559.1 - 2.3e-10 40.3 0.0 2.3e-10 40.3 0.0 2.3 3 0 0 3 3 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EWM26559.1 - 3.4e-10 40.2 1.7 3.6e-05 24.0 0.2 4.3 4 1 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EWM26559.1 - 1.5e-08 33.9 4.2 9.9e-07 27.9 0.0 3.8 4 0 0 4 4 4 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EWM26559.1 - 2.8e-08 32.6 0.9 2.8e-08 32.6 0.6 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 EWM26559.1 - 6.1e-08 32.1 0.1 9e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EWM26559.1 - 9.1e-08 31.3 2.4 1.8e-07 30.3 1.0 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_10 PF13460.1 EWM26559.1 - 1.6e-06 28.2 0.7 4.6e-05 23.5 0.2 2.7 2 1 0 2 2 1 1 NADH(P)-binding GIDA PF01134.17 EWM26559.1 - 2e-05 23.6 0.4 5.1e-05 22.2 0.2 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 EWM26559.1 - 0.00012 21.2 0.3 0.00064 18.8 0.0 2.1 2 0 0 2 2 2 1 Thi4 family 3HCDH_N PF02737.13 EWM26559.1 - 0.00023 20.8 0.1 0.011 15.3 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FMO-like PF00743.14 EWM26559.1 - 0.00027 19.2 0.0 0.002 16.3 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_Gly3P_dh_N PF01210.18 EWM26559.1 - 0.00073 19.2 0.1 0.038 13.7 0.0 2.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PEP_mutase PF13714.1 EWM26559.1 - 0.00084 18.6 0.2 0.036 13.2 0.1 2.3 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase UDPG_MGDP_dh_N PF03721.9 EWM26559.1 - 0.0019 17.5 0.3 0.01 15.1 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.14 EWM26559.1 - 0.0035 16.4 0.8 0.015 14.3 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 EWM26559.1 - 0.0051 16.6 3.2 0.13 12.0 0.0 3.6 4 0 0 4 4 4 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EWM26559.1 - 0.0086 15.0 0.0 0.98 8.2 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.14 EWM26559.1 - 0.016 14.3 0.4 0.97 8.5 0.1 2.8 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Amino_oxidase PF01593.19 EWM26559.1 - 0.017 14.2 0.4 0.029 13.4 0.1 1.5 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase TrkA_N PF02254.13 EWM26559.1 - 0.061 13.3 0.0 33 4.5 0.0 3.3 2 1 1 3 3 3 0 TrkA-N domain AP_endonuc_2 PF01261.19 EWM26559.1 - 0.064 12.5 0.3 1.2 8.3 0.1 2.9 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel F420_oxidored PF03807.12 EWM26559.1 - 0.067 13.6 0.1 21 5.6 0.1 2.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.16 EWM26559.1 - 0.072 12.9 4.2 0.43 10.3 0.2 2.7 2 0 0 2 2 2 0 ThiF family MR_MLE PF01188.16 EWM26559.1 - 0.078 13.5 0.0 0.22 12.0 0.0 1.9 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Lycopene_cycl PF05834.7 EWM26559.1 - 0.11 11.3 1.9 0.091 11.6 0.2 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Shikimate_DH PF01488.15 EWM26559.1 - 0.11 12.5 0.3 3.6 7.6 0.0 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Peptidase_M24 PF00557.19 EWM26560.1 - 1.6e-47 161.8 0.0 1.9e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Glyco_transf_92 PF01697.22 EWM26561.1 - 4.3e-14 52.5 0.1 7.6e-14 51.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.1 EWM26561.1 - 7.4e-12 45.4 0.0 1.5e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glycos_transf_2 PF00535.21 EWM26561.1 - 0.0014 18.3 0.0 0.0049 16.5 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 2 Peptidase_M41 PF01434.13 EWM26562.1 - 0.053 12.9 0.0 3.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Peptidase family M41 PepSY_TM_1 PF13172.1 EWM26562.1 - 0.21 11.3 1.1 0.57 9.9 0.8 1.8 1 0 0 1 1 1 0 PepSY-associated TM helix PI3_PI4_kinase PF00454.22 EWM26563.1 - 1.3e-41 142.6 0.0 7.7e-41 140.0 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase WBS_methylT PF12589.3 EWM26564.1 - 8.7e-16 58.1 12.4 1.3e-15 57.5 8.6 1.2 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EWM26564.1 - 0.013 16.0 0.0 0.04 14.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain RRM_1 PF00076.17 EWM26565.1 - 1e-24 85.8 0.0 1.8e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM26565.1 - 1.1e-19 70.1 0.0 2e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM26565.1 - 6.7e-10 38.6 0.0 1.2e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EWM26565.1 - 0.0016 18.2 0.2 0.0033 17.2 0.0 1.6 1 1 1 2 2 2 1 RNA binding motif API5 PF05918.6 EWM26565.1 - 0.84 8.0 2.8 0.89 7.9 1.9 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) LRR_4 PF12799.2 EWM26566.1 - 1.6e-17 62.6 3.0 4.1e-07 29.4 1.1 4.5 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) Pkinase PF00069.20 EWM26566.1 - 1.7e-16 60.1 0.0 2.8e-14 52.8 0.0 3.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM26566.1 - 1.7e-13 50.2 0.0 1.1e-11 44.2 0.0 2.6 2 1 0 2 2 2 1 Protein tyrosine kinase LRR_8 PF13855.1 EWM26566.1 - 1.9e-12 46.7 1.0 2.6e-06 27.0 0.2 3.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 EWM26566.1 - 2.4e-08 32.8 4.5 0.52 10.5 0.2 6.1 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 EWM26566.1 - 0.00013 21.5 9.1 0.58 10.5 0.2 5.9 6 0 0 6 6 6 2 Leucine rich repeat Kdo PF06293.9 EWM26566.1 - 0.0013 17.7 0.0 0.0029 16.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MCM PF00493.18 EWM26571.1 - 2.2e-106 355.4 0.0 6.2e-102 340.7 0.0 2.1 2 0 0 2 2 2 2 MCM2/3/5 family Mg_chelatase PF01078.16 EWM26571.1 - 6.1e-09 35.3 0.0 1.4e-06 27.6 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EWM26571.1 - 3e-07 30.2 0.0 9.2e-07 28.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EWM26571.1 - 9.6e-06 25.1 0.0 8.6e-05 22.0 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 EWM26571.1 - 1.4e-05 24.6 0.0 3.7e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EWM26571.1 - 0.0013 18.7 0.0 0.0065 16.4 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EWM26571.1 - 0.0085 15.1 0.0 0.021 13.8 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 EWM26571.1 - 0.015 15.4 0.1 0.062 13.5 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EWM26571.1 - 0.022 14.9 0.0 0.32 11.1 0.0 2.8 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EWM26571.1 - 0.035 13.5 0.0 0.35 10.3 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF815 PF05673.8 EWM26571.1 - 0.11 11.4 0.0 0.27 10.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Asp PF00026.18 EWM26574.1 - 3.4e-60 203.9 0.2 1.4e-50 172.3 0.1 2.9 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 EWM26574.1 - 3.2e-05 23.9 0.0 0.00018 21.4 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EWM26574.1 - 0.071 12.6 0.1 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Asp PF00026.18 EWM26575.1 - 4e-60 203.7 0.2 1.8e-50 171.9 0.0 3.2 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 EWM26575.1 - 3.7e-05 23.7 0.0 0.00022 21.2 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EWM26575.1 - 0.087 12.3 0.1 0.26 10.8 0.0 1.8 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal TMEM107 PF14995.1 EWM26575.1 - 0.12 12.5 0.0 1.1 9.3 0.0 2.1 2 0 0 2 2 2 0 Transmembrane protein Hydantoinase_A PF01968.13 EWM26576.1 - 5.5e-81 271.8 1.2 8.9e-81 271.1 0.4 1.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydantoinase_B PF02538.9 EWM26576.1 - 5.1e-63 213.0 0.0 6.6e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydant_A_N PF05378.8 EWM26576.1 - 5.5e-48 162.7 0.4 1e-46 158.6 0.0 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 EWM26576.1 - 0.0025 16.1 0.5 0.99 7.6 0.0 2.2 2 0 0 2 2 2 2 MutL protein DUF1153 PF06627.6 EWM26576.1 - 0.25 11.2 0.6 5.5 6.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1153) Mito_carr PF00153.22 EWM26577.1 - 2.7e-58 193.6 7.3 5.3e-22 77.3 0.2 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 EWM26578.1 - 1.6e-27 92.6 9.2 2.4e-08 32.6 0.9 4.2 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EWM26578.1 - 8.8e-26 89.2 6.9 3.3e-14 52.2 0.9 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.1 EWM26578.1 - 2.2e-24 85.3 4.0 1.1e-11 44.6 0.9 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EWM26578.1 - 1e-22 77.9 7.2 1.3e-07 30.9 0.0 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EWM26578.1 - 4.9e-13 47.7 12.0 0.0021 17.2 0.0 4.9 4 1 1 5 5 5 4 EF hand EF-hand_9 PF14658.1 EWM26578.1 - 2.7e-12 46.4 0.1 1.7e-05 24.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EWM26578.1 - 0.00091 18.9 1.5 3.6 7.3 0.0 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Mistic PF11458.3 EWM26578.1 - 0.081 13.3 1.6 0.32 11.4 0.1 2.4 2 1 0 2 2 2 0 Membrane-integrating protein Mistic DUF3008 PF11450.3 EWM26578.1 - 0.1 12.7 0.1 0.46 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknwon function (DUF3008) DUF3090 PF11290.3 EWM26578.1 - 0.16 11.3 1.0 0.16 11.3 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3090) PB1 PF00564.19 EWM26578.1 - 0.32 10.6 2.0 8.9 6.0 0.5 3.2 3 1 0 3 3 3 0 PB1 domain TRAPPC-Trs85 PF12739.2 EWM26579.1 - 8.6e-65 218.9 0.0 1.3e-64 218.3 0.0 1.3 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TRAPPC9-Trs120 PF08626.6 EWM26579.1 - 0.0017 15.8 0.0 0.0025 15.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit SNAP PF14938.1 EWM26579.1 - 0.031 13.4 0.0 2.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP Inhibitor_I53 PF11714.3 EWM26579.1 - 0.72 9.8 3.1 20 5.2 0.4 2.5 2 0 0 2 2 2 0 Thrombin inhibitor Madanin Mito_carr PF00153.22 EWM26580.1 - 1.9e-32 110.8 9.0 4.6e-13 48.6 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4150 PF13665.1 EWM26580.1 - 0.25 11.2 1.4 0.34 10.8 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4150) ApbA_C PF08546.6 EWM26581.1 - 0.063 13.2 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal DUF1451 PF07295.6 EWM26581.1 - 0.081 12.7 0.6 0.12 12.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) DUF883 PF05957.8 EWM26581.1 - 0.55 10.6 6.5 0.31 11.4 2.7 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) VDE PF07137.6 EWM26585.1 - 0.014 15.2 0.1 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Violaxanthin de-epoxidase (VDE) HAD PF12710.2 EWM26586.1 - 7.3e-18 65.4 0.0 1.6e-17 64.3 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EWM26586.1 - 7e-17 62.5 0.0 9.1e-13 49.1 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EWM26586.1 - 8.7e-17 60.9 1.1 1.3e-16 60.3 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EWM26586.1 - 3.1e-10 39.8 0.0 9.2e-10 38.3 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EWM26586.1 - 0.00049 19.7 0.0 0.0025 17.4 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EWM26586.1 - 0.077 13.2 0.1 0.17 12.1 0.1 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase EamA PF00892.15 EWM26587.1 - 9.6e-11 41.8 19.8 2.9e-09 37.0 1.7 2.6 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EWM26587.1 - 1.5e-10 40.5 15.4 6.3e-10 38.4 10.7 2.0 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 EWM26587.1 - 3.3e-07 30.0 7.0 3.3e-07 30.0 4.8 2.4 1 1 1 2 2 2 1 Triose-phosphate Transporter family EmrE PF13536.1 EWM26587.1 - 0.11 12.7 28.9 0.32 11.1 5.1 3.9 1 1 3 4 4 4 0 Multidrug resistance efflux transporter NfeD PF01957.13 EWM26587.1 - 3.1 7.9 10.1 8.9 6.4 0.2 3.3 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding PCI PF01399.22 EWM26588.1 - 1.1e-14 54.6 0.4 4.8e-14 52.5 0.1 2.1 2 0 0 2 2 2 1 PCI domain CorA PF01544.13 EWM26589.1 - 2.1e-45 155.0 0.4 3.2e-40 138.0 0.1 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein EF-hand_8 PF13833.1 EWM26589.1 - 0.00081 18.9 2.0 0.095 12.3 0.0 3.5 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_1 PF00036.27 EWM26589.1 - 0.016 14.4 0.0 0.053 12.8 0.0 2.0 1 0 0 1 1 1 0 EF hand KxDL PF10241.4 EWM26589.1 - 0.03 14.2 0.6 0.072 12.9 0.4 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein EF-hand_5 PF13202.1 EWM26589.1 - 0.032 13.5 1.0 0.069 12.5 0.1 2.1 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.1 EWM26589.1 - 0.056 13.3 0.1 0.18 11.7 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain HisKA_2 PF07568.7 EWM26589.1 - 0.12 12.2 0.2 0.31 10.9 0.1 1.7 1 0 0 1 1 1 0 Histidine kinase HEAT_2 PF13646.1 EWM26590.1 - 1.6e-15 57.1 7.3 3.8e-12 46.3 1.6 3.7 3 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 EWM26590.1 - 7.9e-11 42.1 16.4 1.1e-08 35.3 1.4 5.4 3 1 2 5 5 5 2 HEAT-like repeat HEAT PF02985.17 EWM26590.1 - 1.7e-07 30.7 9.3 3.5e-05 23.5 0.1 4.0 4 0 0 4 4 4 2 HEAT repeat HEAT_PBS PF03130.11 EWM26590.1 - 0.0019 18.5 18.4 0.026 14.9 0.3 5.3 5 1 0 5 5 5 2 PBS lyase HEAT-like repeat Adaptin_N PF01602.15 EWM26590.1 - 0.0037 15.6 0.0 0.0066 14.8 0.0 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Arm PF00514.18 EWM26590.1 - 0.0051 16.5 3.0 0.024 14.4 0.0 3.3 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.2 EWM26590.1 - 0.01 15.8 4.7 0.63 10.0 0.2 3.1 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion ABC1 PF03109.11 EWM26591.1 - 8.6e-29 99.9 0.0 1.7e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 EWM26591.1 - 3.9e-06 26.7 1.9 7.8e-06 25.7 0.1 2.5 2 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EWM26591.1 - 2.3e-05 23.8 0.0 0.00026 20.4 0.0 2.3 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.20 EWM26591.1 - 0.27 10.3 0.0 0.77 8.8 0.0 1.7 1 1 0 1 1 1 0 Protein kinase domain Complex1_LYR_2 PF13233.1 EWM26592.1 - 0.017 15.5 0.3 0.033 14.6 0.2 1.4 1 0 0 1 1 1 0 Complex1_LYR-like Ras PF00071.17 EWM26593.1 - 1.5e-67 226.0 0.6 1.7e-67 225.8 0.4 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EWM26593.1 - 9.1e-23 81.0 0.0 1.4e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EWM26593.1 - 3.2e-18 65.5 0.1 3.8e-18 65.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EWM26593.1 - 4.5e-07 29.2 0.1 5.2e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EWM26593.1 - 9.9e-06 24.8 0.1 1.2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EWM26593.1 - 1e-05 25.4 0.1 2.3e-05 24.3 0.0 1.5 1 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EWM26593.1 - 3.4e-05 23.3 0.1 8.3e-05 22.0 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EWM26593.1 - 0.00055 20.0 0.0 0.0011 19.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EWM26593.1 - 0.0043 17.2 0.3 0.28 11.3 0.0 2.2 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EWM26593.1 - 0.0073 15.4 0.1 0.057 12.5 0.0 2.1 2 1 1 3 3 3 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EWM26593.1 - 0.023 13.9 0.0 0.11 11.7 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_5 PF07728.9 EWM26593.1 - 0.024 14.3 0.0 0.045 13.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 EWM26593.1 - 0.029 13.8 0.1 0.87 9.0 0.0 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 EWM26593.1 - 0.029 14.3 0.1 0.042 13.8 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.1 EWM26593.1 - 0.029 13.9 0.2 1.3 8.5 0.0 2.6 2 1 1 3 3 3 0 AAA domain ABC_tran PF00005.22 EWM26593.1 - 0.033 14.5 0.1 0.063 13.5 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 EWM26593.1 - 0.04 13.4 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.13 EWM26593.1 - 0.082 11.9 0.0 0.17 10.8 0.0 1.5 1 0 0 1 1 1 0 Septin RNA_helicase PF00910.17 EWM26593.1 - 0.14 12.3 0.2 0.53 10.4 0.1 2.0 1 1 0 1 1 1 0 RNA helicase Nucleoside_tran PF01733.13 EWM26594.1 - 0.00088 18.5 0.1 0.0012 18.0 0.1 1.4 1 0 0 1 1 1 1 Nucleoside transporter Hexokinase_1 PF00349.16 EWM26594.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Hexokinase DUF2318 PF10080.4 EWM26595.1 - 0.056 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) AA_kinase PF00696.23 EWM26596.1 - 8.7e-44 149.8 0.0 1.4e-43 149.1 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family Homoserine_dh PF00742.14 EWM26596.1 - 4.7e-28 98.0 0.0 1.9e-24 86.2 0.0 3.0 2 0 0 2 2 2 2 Homoserine dehydrogenase ACT PF01842.20 EWM26596.1 - 9.2e-15 53.7 0.2 5.4e-06 25.7 0.0 2.8 2 0 0 2 2 2 2 ACT domain NAD_binding_3 PF03447.11 EWM26596.1 - 6.6e-14 52.3 0.0 1.5e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ACT_7 PF13840.1 EWM26596.1 - 1.2e-11 43.9 3.9 1.1e-05 24.8 0.1 3.3 3 0 0 3 3 3 2 ACT domain Dpy-30 PF05186.8 EWM26597.1 - 7.9e-18 63.6 0.1 1.1e-17 63.2 0.1 1.2 1 0 0 1 1 1 1 Dpy-30 motif Pex16 PF08610.5 EWM26598.1 - 4.5e-21 75.1 0.1 2.3e-12 46.5 0.0 2.8 2 1 0 2 2 2 2 Peroxisomal membrane protein (Pex16) TH1 PF04858.8 EWM26599.1 - 1e-36 126.3 0.2 3.1e-22 78.4 0.0 2.1 2 0 0 2 2 2 2 TH1 protein GTP_EFTU PF00009.22 EWM26600.1 - 7.5e-67 224.4 0.0 1.2e-66 223.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EWM26600.1 - 5.5e-36 122.7 1.1 2.1e-35 120.8 0.7 2.0 1 1 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 EWM26600.1 - 1.9e-34 117.3 0.0 4.1e-34 116.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EWM26600.1 - 1.7e-28 98.3 0.3 8.7e-28 96.0 0.1 2.3 3 0 0 3 3 3 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EWM26600.1 - 9.4e-15 54.4 0.1 4.4e-14 52.3 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EWM26600.1 - 0.0019 18.1 0.0 0.004 17.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATPgrasp_Ter PF15632.1 EWM26600.1 - 0.081 11.6 0.1 0.14 10.8 0.1 1.3 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon AIG1 PF04548.11 EWM26600.1 - 0.086 11.9 0.1 0.2 10.7 0.0 1.6 2 0 0 2 2 2 0 AIG1 family Miro PF08477.8 EWM26600.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein DUF4033 PF13225.1 EWM26601.1 - 9.6e-34 114.8 0.1 1.9e-33 113.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4033) WD40 PF00400.27 EWM26602.1 - 1e-07 31.5 2.2 0.013 15.3 0.0 5.2 7 0 0 7 7 7 2 WD domain, G-beta repeat PQQ_3 PF13570.1 EWM26602.1 - 0.02 15.1 1.2 18 5.7 0.1 3.8 4 1 0 4 4 4 0 PQQ-like domain DUF2333 PF10095.4 EWM26605.1 - 0.045 12.3 5.8 0.077 11.6 4.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) Vac_Fusion PF02346.11 EWM26605.1 - 0.053 12.9 1.7 0.15 11.4 0.1 2.4 2 0 0 2 2 2 0 Chordopoxvirus fusion protein Metallophos_3 PF14582.1 EWM26605.1 - 0.1 11.7 3.6 0.22 10.6 2.5 1.5 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily SNF2_N PF00176.18 EWM26606.1 - 8.2e-65 218.5 0.4 1.1e-64 218.0 0.3 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EWM26606.1 - 1.7e-14 53.3 0.1 9.4e-14 51.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EWM26606.1 - 6e-09 35.1 0.0 1.2e-05 24.2 0.0 2.3 2 0 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 EWM26606.1 - 7.4e-09 35.3 0.0 2.6e-08 33.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase PHD PF00628.24 EWM26606.1 - 0.00013 21.5 9.8 0.00013 21.5 6.8 2.4 1 1 1 2 2 2 1 PHD-finger zf-PHD-like PF15446.1 EWM26606.1 - 0.0021 17.4 7.1 0.31 10.3 0.1 2.7 1 1 1 2 2 2 2 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.1 EWM26606.1 - 0.0055 16.0 3.4 0.012 14.8 2.3 1.7 1 0 0 1 1 1 1 PHD-finger Transketolase_N PF00456.16 EWM26607.1 - 1.5e-113 378.9 0.7 1.9e-113 378.6 0.5 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EWM26607.1 - 6.2e-37 126.7 0.0 1.1e-36 125.9 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 EWM26607.1 - 2.1e-08 33.4 0.1 2.9e-06 26.4 0.0 2.4 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.15 EWM26607.1 - 1.4e-07 31.4 0.0 4.9e-07 29.7 0.0 2.0 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.15 EWM26607.1 - 2.7e-06 26.3 0.6 4.8e-06 25.5 0.4 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 EWM26607.1 - 0.0077 15.8 1.8 0.15 11.6 1.2 2.6 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain FHA PF00498.21 EWM26608.1 - 3e-11 43.2 0.1 9.6e-10 38.4 0.0 2.6 2 0 0 2 2 2 1 FHA domain RINGv PF12906.2 EWM26608.1 - 1.6e-10 40.8 5.1 2.7e-10 40.1 3.5 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EWM26608.1 - 0.0013 18.5 4.2 0.0023 17.7 2.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EWM26608.1 - 0.26 10.9 7.3 0.3 10.7 3.8 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EWM26608.1 - 0.35 10.5 5.1 0.64 9.7 3.5 1.4 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 EWM26608.1 - 1.6 8.7 4.4 3.9 7.5 3.1 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain Kelch_4 PF13418.1 EWM26609.1 - 6.1e-32 109.1 2.4 7.9e-10 38.3 0.0 4.4 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.1 EWM26609.1 - 1.1e-30 105.0 15.0 3.2e-12 46.2 0.1 5.9 5 1 0 5 5 5 5 Galactose oxidase, central domain Kelch_2 PF07646.10 EWM26609.1 - 6.6e-25 85.8 2.3 4.1e-08 32.6 0.0 5.1 5 0 0 5 5 5 4 Kelch motif BTB PF00651.26 EWM26609.1 - 2.1e-24 85.6 0.0 1.5e-23 82.8 0.0 2.1 1 1 1 2 2 2 1 BTB/POZ domain Kelch_1 PF01344.20 EWM26609.1 - 7.8e-24 82.9 0.0 3.4e-10 39.3 0.0 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.1 EWM26609.1 - 1.9e-23 81.5 0.1 9.2e-08 31.9 0.0 4.5 2 1 2 4 4 4 4 Kelch motif Kelch_5 PF13854.1 EWM26609.1 - 4.8e-21 74.2 0.2 1.6e-08 34.3 0.0 3.9 4 0 0 4 4 4 3 Kelch motif HTH_20 PF12840.2 EWM26609.1 - 0.022 14.5 0.4 0.39 10.5 0.3 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain MgtC PF02308.11 EWM26610.1 - 1.3e-27 96.2 7.3 2.1e-27 95.5 5.1 1.3 1 0 0 1 1 1 1 MgtC family GRASP55_65 PF04495.9 EWM26611.1 - 1.2e-61 206.7 0.0 6.9e-43 145.9 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 EWM26611.1 - 0.0057 16.5 0.0 1.1 9.1 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.19 EWM26611.1 - 0.012 15.7 0.0 4 7.6 0.0 2.3 2 0 0 2 2 2 0 PDZ domain (Also known as DHR or GLGF) EPSP_synthase PF00275.15 EWM26612.1 - 1.3e-101 340.0 0.0 1.6e-101 339.8 0.0 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) EPSP_synthase PF00275.15 EWM26613.1 - 1.3e-101 340.0 0.0 1.6e-101 339.8 0.0 1.0 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) GARS_A PF01071.14 EWM26614.1 - 4.1e-79 264.6 0.0 6.9e-79 263.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Formyl_trans_N PF00551.14 EWM26614.1 - 3.3e-42 144.0 0.0 5.1e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase GARS_N PF02844.10 EWM26614.1 - 2.3e-35 121.0 0.1 5e-35 119.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.11 EWM26614.1 - 5e-25 87.4 0.6 1.3e-24 86.1 0.4 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp_4 PF13535.1 EWM26614.1 - 4.2e-18 65.7 0.0 8.5e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EWM26614.1 - 1.1e-11 44.0 0.0 1.5e-10 40.3 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.12 EWM26614.1 - 1.9e-08 33.8 0.0 3.8e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 EWM26614.1 - 1.4e-05 24.6 0.0 2.6e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp PF02222.17 EWM26614.1 - 3.1e-05 23.4 0.0 5.8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EWM26614.1 - 0.00015 21.6 0.0 0.00061 19.6 0.0 2.0 2 1 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EWM26614.1 - 0.0027 17.1 0.0 0.0054 16.1 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_5 PF13549.1 EWM26614.1 - 0.075 12.2 0.1 0.18 11.0 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain Mito_carr PF00153.22 EWM26615.1 - 1.8e-70 232.7 3.8 5.6e-23 80.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Med25 PF11232.3 EWM26615.1 - 0.028 14.0 0.0 0.26 10.9 0.0 2.1 2 0 0 2 2 2 0 Mediator complex subunit 25 PTOV activation and synapsin 2 Thioredoxin_7 PF13899.1 EWM26616.1 - 6.6e-11 42.0 0.0 1.5e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.1 EWM26616.1 - 8.1e-06 25.2 0.0 2e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain LTV PF04180.9 EWM26617.1 - 2e-08 34.1 1.7 2e-08 34.1 1.2 3.2 3 1 0 3 3 3 2 Low temperature viability protein TPR_16 PF13432.1 EWM26618.1 - 3.5e-08 33.8 1.8 4.8e-05 23.8 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EWM26618.1 - 1.6e-07 31.5 0.1 0.022 15.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EWM26618.1 - 9.7e-06 25.7 2.7 0.97 10.2 0.0 4.9 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 EWM26618.1 - 1.5e-05 24.5 1.2 0.46 10.1 0.0 3.5 3 1 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 EWM26618.1 - 2.8e-05 23.6 2.4 0.014 15.3 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EWM26618.1 - 0.0011 19.2 1.2 6 7.5 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EWM26618.1 - 0.01 15.4 0.1 0.21 11.2 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EWM26618.1 - 0.036 13.8 0.1 3.7 7.5 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 EWM26618.1 - 0.043 13.6 0.1 0.23 11.3 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat adh_short PF00106.20 EWM26619.1 - 7.8e-16 58.4 0.0 1.2e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EWM26619.1 - 7.1e-08 32.5 0.0 1.1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EWM26619.1 - 9.4e-05 22.1 0.0 0.00025 20.7 0.0 1.6 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EWM26619.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF4211 PF13926.1 EWM26620.1 - 1.3e-11 44.1 6.1 1.3e-11 44.1 4.3 3.7 3 1 0 3 3 3 2 Domain of unknown function (DUF4211) NIF PF03031.13 EWM26621.1 - 6e-21 74.7 0.0 1.5e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 EWM26621.1 - 2e-09 37.1 0.0 4.2e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EWM26621.1 - 0.026 14.6 0.0 0.049 13.7 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain COX5B PF01215.14 EWM26622.1 - 3.9e-09 36.2 0.0 5.8e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Myb_DNA-binding PF00249.26 EWM26623.1 - 2e-06 27.7 0.1 5.9e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EWM26623.1 - 0.00015 21.7 0.9 0.00045 20.2 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain SSXT PF05030.7 EWM26623.1 - 0.00037 20.0 0.4 0.00037 20.0 0.3 2.3 2 0 0 2 2 2 1 SSXT protein (N-terminal region) Amidohydro_2 PF04909.9 EWM26624.1 - 9.2e-23 81.1 0.0 1.5e-22 80.4 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase CS PF04969.11 EWM26625.1 - 7.1e-06 26.4 0.0 1.1e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 CS domain NMO PF03060.10 EWM26626.1 - 4.3e-29 101.7 0.0 5e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EWM26626.1 - 0.00018 20.5 0.2 0.00031 19.7 0.1 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EWM26626.1 - 0.023 13.5 0.2 0.034 12.9 0.1 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Rad21_Rec8_N PF04825.8 EWM26627.1 - 5.3e-30 103.6 0.0 8.1e-30 103.0 0.0 1.2 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EWM26627.1 - 1.8e-10 39.8 0.0 3.3e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EWM26627.1 - 0.012 15.2 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 ScpA/B protein Nop14 PF04147.7 EWM26627.1 - 9.5 3.9 9.5 13 3.5 6.6 1.1 1 0 0 1 1 1 0 Nop14-like family tRNA-synt_1_2 PF13603.1 EWM26628.1 - 3e-61 205.9 0.0 4.8e-61 205.2 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1 PF00133.17 EWM26628.1 - 1.8e-59 201.2 0.0 7.5e-37 126.6 0.0 3.9 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EWM26628.1 - 7.5e-24 84.1 0.0 3.5e-15 55.5 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EWM26628.1 - 4.1e-16 59.1 0.0 1.1e-15 57.6 0.0 1.8 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EWM26628.1 - 0.00055 19.1 0.0 0.0028 16.8 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 EWM26628.1 - 0.0043 15.9 0.0 0.0071 15.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) tRNA-synt_1b PF00579.20 EWM26628.1 - 0.027 13.5 0.0 0.053 12.6 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) tRNA-synt_1f PF01921.13 EWM26628.1 - 0.048 12.3 0.0 0.098 11.3 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (K) TetM_leader PF08076.6 EWM26629.1 - 0.049 13.1 1.2 2.4 7.7 0.1 2.6 2 0 0 2 2 2 0 Tetracycline resistance determinant leader peptide HA2 PF04408.18 EWM26630.1 - 3.3e-25 88.0 0.8 2.5e-24 85.2 0.0 3.1 3 0 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EWM26630.1 - 1.1e-23 83.2 0.0 3.6e-23 81.5 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EWM26630.1 - 3.8e-10 39.4 0.0 1e-09 38.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EWM26630.1 - 6e-06 25.8 0.1 1.7e-05 24.3 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EWM26630.1 - 2.4e-05 24.4 0.0 7.1e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EWM26630.1 - 0.0029 16.5 0.0 0.0061 15.5 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 EWM26630.1 - 0.0061 16.4 0.0 1.4 8.6 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_23 PF13476.1 EWM26630.1 - 0.03 14.6 0.0 0.03 14.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.1 EWM26630.1 - 0.04 13.8 0.1 0.38 10.6 0.0 2.3 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EWM26630.1 - 0.046 13.7 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain Radical_SAM PF04055.16 EWM26630.1 - 0.09 12.9 0.1 0.23 11.6 0.1 1.7 1 0 0 1 1 1 0 Radical SAM superfamily Flavi_DEAD PF07652.9 EWM26630.1 - 0.11 12.1 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 Flavivirus DEAD domain NB-ARC PF00931.17 EWM26630.1 - 0.13 11.1 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain adh_short PF00106.20 EWM26631.1 - 1.2e-16 61.0 0.0 1.8e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EWM26631.1 - 9.4e-07 28.8 0.0 1.4e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EWM26631.1 - 0.014 15.4 0.1 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding KR PF08659.5 EWM26631.1 - 0.022 14.4 0.6 0.08 12.6 0.4 2.0 1 1 0 1 1 1 0 KR domain Pkinase PF00069.20 EWM26635.1 - 9.3e-47 159.3 0.0 1.3e-46 158.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM26635.1 - 1.8e-37 128.7 0.0 2.3e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EWM26635.1 - 3.2e-06 27.0 0.0 0.024 14.4 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Trypan_PARP PF05887.6 EWM26635.1 - 0.52 10.1 13.6 0.82 9.4 9.5 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PTS_EIIB PF00367.15 EWM26636.1 - 0.076 12.2 0.4 0.17 11.1 0.0 1.8 2 0 0 2 2 2 0 phosphotransferase system, EIIB DUF21 PF01595.15 EWM26637.1 - 5e-33 113.9 0.2 7.2e-33 113.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EWM26637.1 - 0.0015 18.2 0.0 0.016 14.9 0.0 2.7 2 1 0 2 2 2 1 CBS domain YrhC PF14143.1 EWM26637.1 - 0.032 14.1 2.5 0.077 12.9 1.7 1.6 1 0 0 1 1 1 0 YrhC-like protein BEX PF04538.7 EWM26637.1 - 0.063 13.4 2.4 0.15 12.2 1.7 1.6 1 0 0 1 1 1 0 Brain expressed X-linked like family DUF1049 PF06305.6 EWM26637.1 - 0.33 10.4 3.0 2.7 7.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) APC_CDC26 PF10471.4 EWM26637.1 - 1.1 9.9 6.4 1.3 9.8 3.3 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex APC subunit 1 ABC2_membrane PF01061.19 EWM26638.1 - 5.9e-24 84.4 25.5 5.9e-24 84.4 17.7 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 EWM26638.1 - 5.1e-21 75.4 0.0 7.9e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EWM26638.1 - 4.9e-10 39.8 0.0 2e-07 31.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 EWM26638.1 - 0.00013 21.2 0.0 0.0013 18.0 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EWM26638.1 - 0.00019 21.4 0.0 0.00037 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EWM26638.1 - 0.00021 21.4 0.0 0.007 16.5 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EWM26638.1 - 0.00022 21.6 0.2 0.00043 20.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EWM26638.1 - 0.0026 16.9 0.0 0.0041 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_15 PF13175.1 EWM26638.1 - 0.012 14.7 0.0 0.069 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 EWM26638.1 - 0.012 15.0 0.3 0.029 13.9 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 EWM26638.1 - 0.036 13.7 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_25 PF13481.1 EWM26638.1 - 0.047 13.0 0.0 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EWM26638.1 - 0.08 12.9 0.1 0.3 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EWM26638.1 - 0.087 11.6 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ATP-synt_ab PF00006.20 EWM26638.1 - 0.092 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.7 EWM26638.1 - 0.11 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain SbcCD_C PF13558.1 EWM26638.1 - 0.15 11.9 0.2 0.95 9.4 0.1 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC2_membrane_3 PF12698.2 EWM26638.1 - 0.18 10.8 34.6 1.7 7.5 24.2 2.0 1 1 0 1 1 1 0 ABC-2 family transporter protein Rad17 PF03215.10 EWM26638.1 - 0.22 10.1 0.1 0.33 9.5 0.1 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Methyltransf_28 PF02636.12 EWM26639.1 - 1.4e-66 224.4 0.0 2e-66 223.9 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase LisH PF08513.6 EWM26640.1 - 0.013 15.2 0.1 0.033 13.9 0.1 1.8 1 0 0 1 1 1 0 LisH Abhydrolase_6 PF12697.2 EWM26641.1 - 9.5e-30 104.1 2.4 1.4e-29 103.6 1.7 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM26641.1 - 1.1e-16 60.8 0.0 1.8e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EWM26641.1 - 2.6e-13 50.0 0.0 5.3e-13 49.0 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EWM26641.1 - 0.00028 20.4 0.0 0.00041 19.8 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.15 EWM26641.1 - 0.00047 20.4 0.2 0.0081 16.4 0.1 2.4 1 1 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 EWM26641.1 - 0.005 16.6 0.0 0.0097 15.7 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 EWM26641.1 - 0.018 14.3 0.0 0.67 9.1 0.0 2.8 2 1 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 EWM26641.1 - 0.064 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 EWM26641.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein DUF4050 PF13259.1 EWM26644.1 - 0.00014 21.8 0.0 0.00021 21.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) DUF2721 PF11026.3 EWM26645.1 - 1.4 8.5 9.2 3.7 7.1 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) HEAT PF02985.17 EWM26646.1 - 0.0078 16.2 0.7 0.042 13.9 0.0 2.8 3 0 0 3 3 3 1 HEAT repeat RIX1 PF08167.7 EWM26646.1 - 0.047 13.3 0.0 0.084 12.5 0.0 1.4 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis Proteasom_PSMB PF10508.4 EWM26646.1 - 0.059 11.6 0.0 0.11 10.6 0.0 1.4 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit His_biosynth PF00977.16 EWM26649.1 - 3.3e-45 154.1 0.0 1.6e-30 106.1 0.0 2.7 2 1 0 2 2 2 2 Histidine biosynthesis protein GATase PF00117.23 EWM26649.1 - 2.2e-21 76.1 0.0 3.8e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 EWM26649.1 - 0.001 18.7 0.0 0.3 10.6 0.0 2.4 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 EWM26649.1 - 0.0015 18.1 0.0 0.0032 17.0 0.0 1.5 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 EWM26649.1 - 0.12 11.7 0.1 6 6.2 0.0 2.4 2 0 0 2 2 2 0 Peptidase C26 AhpC-TSA_2 PF13911.1 EWM26651.1 - 5.4e-08 32.7 0.1 8.6e-08 32.1 0.1 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.5 EWM26651.1 - 0.037 13.5 0.0 0.79 9.2 0.0 2.2 1 1 0 1 1 1 0 Redoxin MMR_HSR1 PF01926.18 EWM26652.1 - 6.5e-16 58.3 0.0 1.8e-15 56.9 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EWM26652.1 - 6e-07 28.8 0.0 1.4e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EWM26652.1 - 6.6e-06 26.0 0.0 0.002 17.9 0.0 3.0 2 1 1 3 3 3 2 Dynamin family AIG1 PF04548.11 EWM26652.1 - 2.3e-05 23.5 0.0 7e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 AIG1 family Miro PF08477.8 EWM26652.1 - 0.0058 17.1 0.0 0.015 15.8 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein MobB PF03205.9 EWM26652.1 - 0.093 12.4 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B WD40 PF00400.27 EWM26654.1 - 1.1e-32 110.7 10.5 5.7e-08 32.3 0.0 7.6 7 1 0 7 7 7 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EWM26654.1 - 0.031 13.0 0.0 0.16 10.7 0.0 1.9 2 0 0 2 2 2 0 Nup133 N terminal like Nup160 PF11715.3 EWM26654.1 - 0.16 10.0 0.2 4 5.4 0.0 3.0 2 1 1 3 3 3 0 Nucleoporin Nup120/160 FixQ PF05545.6 EWM26655.1 - 0.09 12.4 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ UPF0160 PF03690.8 EWM26656.1 - 5.3e-115 384.2 0.0 6e-115 384.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) GTP_CH_N PF12471.3 EWM26656.1 - 0.12 11.9 0.0 0.53 9.8 0.0 1.8 2 0 0 2 2 2 0 GTP cyclohydrolase N terminal TIM PF00121.13 EWM26658.1 - 1.7e-77 259.7 0.0 2e-77 259.5 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Acyl_transf_1 PF00698.16 EWM26659.1 - 8e-59 199.5 0.0 1.3e-58 198.8 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EWM26659.1 - 1.6e-46 158.2 8.5 1.6e-45 155.0 0.1 3.5 4 0 0 4 4 4 2 KR domain adh_short PF00106.20 EWM26659.1 - 1.9e-41 141.7 7.9 5.2e-40 137.0 0.0 4.4 3 1 1 4 4 4 2 short chain dehydrogenase ketoacyl-synt PF00109.21 EWM26659.1 - 1.2e-40 139.6 0.1 2.6e-40 138.5 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EWM26659.1 - 1.2e-27 96.0 0.2 3.7e-27 94.5 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 EWM26659.1 - 1.1e-24 86.7 0.0 1.3e-23 83.2 0.0 2.6 3 0 0 3 3 3 1 Male sterility protein ADH_zinc_N PF00107.21 EWM26659.1 - 3.3e-23 81.6 0.0 1.5e-22 79.5 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EWM26659.1 - 6.9e-14 52.8 0.0 4.1e-13 50.3 0.0 2.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.16 EWM26659.1 - 3.8e-12 46.1 0.0 1.5e-05 24.5 0.0 2.5 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family PS-DH PF14765.1 EWM26659.1 - 4.3e-10 39.2 0.0 8.7e-08 31.6 0.0 2.3 2 0 0 2 2 2 1 Polyketide synthase dehydratase ADH_N PF08240.7 EWM26659.1 - 1.3e-07 31.3 0.0 6.5e-07 29.0 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 EWM26659.1 - 2.4e-06 27.7 0.1 9.1e-06 25.8 0.1 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EWM26659.1 - 1.3e-05 24.3 0.0 5.3e-05 22.3 0.0 2.0 1 0 0 1 1 1 1 Thiolase, N-terminal domain Polysacc_synt_2 PF02719.10 EWM26659.1 - 0.00063 18.7 0.0 0.0026 16.7 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Acetyltransf_1 PF00583.19 EWM26660.1 - 8.7e-15 54.5 0.1 1.7e-14 53.6 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EWM26660.1 - 5.7e-08 32.4 0.1 1.6e-07 31.0 0.0 1.7 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.1 EWM26660.1 - 9.8e-07 28.9 0.1 1.5e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EWM26660.1 - 4.7e-06 26.6 0.1 6.3e-06 26.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EWM26660.1 - 9.2e-05 22.6 0.0 0.00015 21.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EWM26660.1 - 9.6e-05 22.4 0.7 0.00017 21.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EWM26660.1 - 0.0038 17.0 0.1 0.0057 16.5 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EWM26660.1 - 0.033 13.7 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EWM26660.1 - 0.06 13.2 0.1 0.087 12.6 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Cellulase PF00150.13 EWM26661.1 - 1.2e-34 119.7 4.1 1.6e-34 119.3 2.8 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Methyltransf_24 PF13578.1 EWM26663.1 - 0.14 12.9 0.0 0.33 11.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain TPR_19 PF14559.1 EWM26664.1 - 3e-13 49.8 0.3 5.8e-08 32.9 0.0 4.4 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EWM26664.1 - 2.7e-09 36.8 6.1 0.0016 18.9 0.0 5.2 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 EWM26664.1 - 1.4e-08 35.1 10.1 0.00014 22.4 0.0 4.0 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EWM26664.1 - 3.4e-08 33.0 1.1 0.00017 21.1 0.5 2.8 1 1 0 2 2 2 2 TPR repeat TPR_17 PF13431.1 EWM26664.1 - 2.2e-07 30.5 0.0 0.044 14.0 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EWM26664.1 - 0.00014 21.5 4.2 0.018 14.8 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 EWM26664.1 - 0.00062 19.6 6.9 0.054 13.4 0.1 4.0 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 EWM26664.1 - 0.0073 16.1 0.3 0.046 13.5 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EWM26664.1 - 0.023 14.8 0.8 0.084 13.0 0.2 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EWM26664.1 - 0.11 13.0 5.2 17 6.1 0.0 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 EWM26664.1 - 0.16 11.7 0.7 1.6 8.6 0.0 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EWM26664.1 - 0.17 11.5 1.7 3.9 7.2 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1350 PF07082.6 EWM26665.1 - 8.7e-52 175.6 0.2 2.1e-34 118.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1350) Abhydrolase_5 PF12695.2 EWM26665.1 - 0.0083 15.8 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EWM26665.1 - 0.039 13.8 0.2 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family APG6 PF04111.7 EWM26665.1 - 2.9 6.8 7.7 4.7 6.1 5.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 GCV_T PF01571.16 EWM26666.1 - 3.5e-63 212.7 0.1 4.4e-63 212.4 0.1 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EWM26666.1 - 1.3e-18 66.7 0.0 2.4e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 EWM26666.1 - 5e-06 26.4 0.0 1.3e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 Sarcosine oxidase, gamma subunit family Sulfate_transp PF00916.15 EWM26667.1 - 7.7e-18 64.4 4.4 7.7e-18 64.4 3.0 2.3 3 0 0 3 3 3 1 Sulfate transporter family cNMP_binding PF00027.24 EWM26667.1 - 2.8e-14 52.6 0.0 5.2e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 EWM26667.1 - 4e-08 32.6 0.0 9.2e-08 31.5 0.0 1.6 1 0 0 1 1 1 1 STAS domain Glyco_transf_90 PF05686.7 EWM26669.1 - 1.7e-32 112.6 0.0 2.5e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 CitMHS PF03600.11 EWM26670.1 - 1e-20 73.6 15.9 1.2e-20 73.4 10.5 1.6 1 1 0 1 1 1 1 Citrate transporter CBS PF00571.23 EWM26670.1 - 2.5e-14 52.7 2.2 5.1e-09 35.7 0.6 2.8 2 0 0 2 2 2 2 CBS domain zf-C2H2_6 PF13912.1 EWM26671.1 - 0.0098 15.7 3.5 0.0098 15.7 2.4 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EWM26671.1 - 3.1 8.3 11.3 22 5.6 2.8 3.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EWM26671.1 - 8.2 7.0 14.3 12 6.4 1.3 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type Surfac_D-trimer PF09006.6 EWM26672.1 - 0.12 12.1 1.7 3.7 7.3 0.0 4.6 4 0 0 4 4 4 0 Lung surfactant protein D coiled-coil trimerisation Reo_sigmaC PF04582.7 EWM26672.1 - 5.1 6.1 44.1 0.37 9.9 4.0 6.0 3 2 2 5 5 5 0 Reovirus sigma C capsid protein PLDc_N PF13396.1 EWM26673.1 - 1.9e-06 27.4 2.2 3e-06 26.7 1.5 1.4 1 0 0 1 1 1 1 Phospholipase_D-nuclease N-terminal PsbX PF06596.6 EWM26673.1 - 0.0086 15.7 0.9 0.019 14.5 0.6 1.6 1 0 0 1 1 1 1 Photosystem II reaction centre X protein (PsbX) Ycf66_N PF07444.6 EWM26673.1 - 0.014 15.0 0.3 0.022 14.4 0.2 1.2 1 0 0 1 1 1 0 Ycf66 protein N-terminus DUF347 PF03988.7 EWM26673.1 - 0.43 10.5 2.1 0.98 9.3 0.1 2.1 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) cobW PF02492.14 EWM26674.1 - 1.8e-47 161.0 0.0 2.6e-47 160.5 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EWM26674.1 - 1.3e-05 24.8 0.0 3.8e-05 23.3 0.0 1.9 2 1 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain Viral_helicase1 PF01443.13 EWM26674.1 - 0.0026 17.3 0.1 0.2 11.1 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 EWM26674.1 - 0.016 14.1 0.1 0.026 13.4 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.1 EWM26674.1 - 0.025 14.7 0.0 0.047 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EWM26674.1 - 0.025 14.2 1.0 0.072 12.7 0.2 2.3 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EWM26674.1 - 0.03 14.2 0.0 0.062 13.2 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 EWM26674.1 - 0.031 13.8 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 EWM26674.1 - 0.045 13.4 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_18 PF13238.1 EWM26674.1 - 0.052 13.8 0.7 0.31 11.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EWM26674.1 - 0.055 12.9 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_19 PF13245.1 EWM26674.1 - 0.065 12.9 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 EWM26674.1 - 0.073 12.9 0.1 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 EWM26674.1 - 0.079 12.1 0.1 0.18 11.0 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_33 PF13671.1 EWM26674.1 - 0.081 12.7 0.1 0.29 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EWM26674.1 - 0.082 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 EWM26674.1 - 0.12 12.0 0.1 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.1 EWM26674.1 - 0.13 12.5 0.1 0.21 11.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain Sad1_UNC PF07738.8 EWM26675.1 - 7.4e-11 41.9 0.0 1.6e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF641 PF04859.7 EWM26675.1 - 0.047 13.4 20.0 1.3 8.8 4.8 3.6 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) Mating_N PF12731.2 EWM26675.1 - 0.38 10.6 5.2 0.16 11.8 0.2 3.0 3 0 0 3 3 3 0 Mating-type protein beta 1 DUF1664 PF07889.7 EWM26675.1 - 1.2 8.8 17.8 1.9 8.2 2.5 4.1 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) AAA_13 PF13166.1 EWM26675.1 - 4.2 5.6 20.7 2.3 6.5 9.1 2.1 1 1 1 2 2 2 0 AAA domain Pox_MCEL PF03291.11 EWM26676.1 - 2.6e-37 128.4 0.0 2e-31 109.1 0.0 2.6 2 1 0 2 2 2 2 mRNA capping enzyme NIF PF03031.13 EWM26676.1 - 2.4e-14 53.2 0.0 4.1e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Methyltransf_18 PF12847.2 EWM26676.1 - 4.2e-06 27.3 0.1 9.4e-05 22.9 0.1 2.9 2 0 0 2 2 2 1 Methyltransferase domain mRNA_cap_C PF03919.10 EWM26676.1 - 0.0007 19.8 0.0 0.0014 18.9 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain Methyltransf_11 PF08241.7 EWM26676.1 - 0.0025 18.2 0.0 0.015 15.8 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain mRNA_cap_enzyme PF01331.14 EWM26676.1 - 0.0036 17.0 0.0 0.034 13.8 0.0 2.2 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain Methyltransf_31 PF13847.1 EWM26676.1 - 0.0079 15.7 0.0 0.2 11.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Ank_4 PF13637.1 EWM26677.1 - 4.7e-18 65.1 0.1 6.7e-08 32.8 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EWM26677.1 - 4.9e-17 62.0 0.0 1.1e-10 41.6 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EWM26677.1 - 1.9e-16 59.7 0.0 6.5e-13 48.4 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EWM26677.1 - 1.3e-15 56.2 1.5 2.1e-08 33.5 0.0 4.6 4 1 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 EWM26677.1 - 2.6e-08 33.2 0.0 0.00057 19.8 0.0 3.6 3 1 0 3 3 3 2 Ankyrin repeat Pik1 PF11522.3 EWM26679.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Yeast phosphatidylinositol-4-OH kinase Pik1 Ras PF00071.17 EWM26680.1 - 1e-62 210.2 0.1 1.2e-62 210.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EWM26680.1 - 4.8e-19 68.9 0.0 7.6e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EWM26680.1 - 2.1e-16 59.6 0.0 2.6e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EWM26680.1 - 1.9e-06 27.4 0.1 7.7e-06 25.4 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EWM26680.1 - 6.6e-06 26.0 0.0 9.5e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EWM26680.1 - 1.6e-05 24.1 0.0 2e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EWM26680.1 - 0.00052 20.1 0.0 0.00096 19.2 0.0 1.5 1 1 1 2 2 2 1 AAA domain SRPRB PF09439.5 EWM26680.1 - 0.00077 18.7 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EWM26680.1 - 0.029 13.6 0.0 0.27 10.5 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF258 PF03193.11 EWM26680.1 - 0.039 13.1 0.0 0.12 11.6 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function, DUF258 CENP-M PF11111.3 EWM26680.1 - 0.042 13.0 0.0 0.063 12.5 0.0 1.2 1 0 0 1 1 1 0 Centromere protein M (CENP-M) AAA_16 PF13191.1 EWM26680.1 - 0.057 13.4 0.1 0.21 11.5 0.0 1.8 2 1 0 2 2 2 0 AAA ATPase domain DAP3 PF10236.4 EWM26680.1 - 0.084 11.7 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.7 EWM26680.1 - 0.13 11.9 0.0 0.25 10.9 0.0 1.5 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.1 EWM26680.1 - 0.59 9.7 0.0 0.59 9.7 0.0 2.2 2 0 0 2 2 1 0 P-loop containing region of AAA domain HCO3_cotransp PF00955.16 EWM26681.1 - 5.1e-124 414.7 14.1 1.4e-65 221.9 2.1 2.2 1 1 1 2 2 2 2 HCO3- transporter family PRKCSH_1 PF13015.1 EWM26682.1 - 2.9e-24 85.3 0.4 5.1e-24 84.5 0.3 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH-like PF12999.2 EWM26682.1 - 1.6e-18 66.8 3.5 3.3e-18 65.8 2.4 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH PF07915.8 EWM26682.1 - 0.0064 17.2 0.1 0.018 15.8 0.1 1.8 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Zip PF02535.17 EWM26683.1 - 7.2e-56 189.4 14.0 1.8e-55 188.1 9.7 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter YjgP_YjgQ PF03739.9 EWM26683.1 - 0.05 12.3 0.9 0.11 11.1 0.6 1.5 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Gp_dh_C PF02800.15 EWM26684.1 - 3.1e-73 244.4 0.0 4.7e-73 243.8 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EWM26684.1 - 5.3e-36 123.8 0.4 9.7e-36 122.9 0.3 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Peptidase_M48 PF01435.13 EWM26686.1 - 3.5e-46 157.5 0.1 1.4e-38 132.7 0.1 2.4 3 0 0 3 3 3 2 Peptidase family M48 SprT-like PF10263.4 EWM26686.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 SprT-like family DUF900 PF05990.7 EWM26686.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PPR_2 PF13041.1 EWM26689.1 - 1.8e-55 184.7 0.0 1.3e-08 34.7 0.0 15.1 12 4 3 15 15 15 10 PPR repeat family PPR PF01535.15 EWM26689.1 - 2.8e-37 124.1 15.2 0.0025 17.6 0.0 18.3 20 0 0 20 20 19 6 PPR repeat PPR_3 PF13812.1 EWM26689.1 - 2.4e-32 108.4 28.6 0.00034 20.6 0.0 18.4 18 1 1 19 19 18 6 Pentatricopeptide repeat domain PPR_1 PF12854.2 EWM26689.1 - 9.1e-30 101.8 10.0 0.0036 16.7 0.0 13.0 14 0 0 14 14 14 6 PPR repeat TPR_14 PF13428.1 EWM26689.1 - 4.6e-06 26.8 42.5 2.4 9.0 0.1 14.6 15 2 2 17 17 13 1 Tetratricopeptide repeat Apc3 PF12895.2 EWM26689.1 - 0.0014 18.7 0.6 10 6.3 0.0 5.5 5 2 1 6 6 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Smr PF01713.16 EWM26689.1 - 0.0018 18.3 0.0 0.018 15.2 0.0 2.7 2 0 0 2 2 2 1 Smr domain TPR_19 PF14559.1 EWM26689.1 - 0.014 15.6 11.0 25 5.2 0.0 8.1 9 1 1 10 10 8 0 Tetratricopeptide repeat TPR_11 PF13414.1 EWM26689.1 - 0.048 13.3 0.7 8 6.1 0.0 4.4 4 0 0 4 4 4 0 TPR repeat Ank_2 PF12796.2 EWM26689.1 - 0.049 13.9 1.2 0.46 10.8 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeats (3 copies) TPR_10 PF13374.1 EWM26689.1 - 0.059 13.3 0.1 0.059 13.3 0.1 8.7 11 0 0 11 11 10 0 Tetratricopeptide repeat DUF3368 PF11848.3 EWM26689.1 - 0.064 12.8 3.2 7 6.2 0.1 5.3 6 1 1 7 7 7 0 Domain of unknown function (DUF3368) TPR_7 PF13176.1 EWM26689.1 - 0.39 10.6 16.8 5.2 7.1 0.0 7.2 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_2 PF07719.12 EWM26689.1 - 1.1 9.3 9.5 2.3 8.3 0.1 6.3 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_12 PF13424.1 EWM26689.1 - 6.4 6.7 16.3 3.1 7.7 0.0 7.2 8 2 0 8 8 8 0 Tetratricopeptide repeat Archease PF01951.11 EWM26690.1 - 3.1e-45 153.5 0.1 5e-45 152.8 0.0 1.3 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) COPI_assoc PF08507.5 EWM26691.1 - 0.00012 21.7 3.0 0.00021 20.9 2.1 1.3 1 0 0 1 1 1 1 COPI associated protein DUF3357 PF11837.3 EWM26691.1 - 0.0027 17.5 0.4 0.0062 16.3 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3357) PIRT PF15099.1 EWM26691.1 - 0.061 12.5 0.2 0.061 12.5 0.1 2.2 2 1 1 3 3 3 0 Phosphoinositide-interacting protein family DUF2077 PF09850.4 EWM26691.1 - 0.073 12.4 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) HABP4_PAI-RBP1 PF04774.10 EWM26693.1 - 2e-07 31.4 5.8 3e-07 30.9 4.0 1.2 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family DUF2231 PF09990.4 EWM26696.1 - 1.2e-12 48.0 8.1 1.2e-12 48.0 5.6 1.7 2 0 0 2 2 2 1 Predicted membrane protein (DUF2231) Tmemb_18A PF09771.4 EWM26696.1 - 0.21 11.5 0.8 2.1 8.3 0.1 2.2 2 0 0 2 2 2 0 Transmembrane protein 188 DUF4149 PF13664.1 EWM26696.1 - 0.24 11.4 5.2 1.1 9.4 0.2 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4149) Metallophos PF00149.23 EWM26697.1 - 4.2e-13 49.1 0.0 6.4e-13 48.5 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EWM26697.1 - 7.5e-08 32.3 0.0 9.4e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 EWM26697.1 - 0.05 12.7 0.0 0.075 12.1 0.0 1.2 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Zn_clus PF00172.13 EWM26698.1 - 6.3e-09 35.6 11.0 1.1e-08 34.7 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain API5 PF05918.6 EWM26698.1 - 0.68 8.3 2.1 1.2 7.5 1.5 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) MaoC_dehydratas PF01575.14 EWM26699.1 - 1.1e-15 57.0 0.2 2e-15 56.2 0.1 1.4 1 0 0 1 1 1 1 MaoC like domain Exo_endo_phos PF03372.18 EWM26700.1 - 5.7e-10 39.5 0.2 4.2e-09 36.7 0.0 2.1 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family RRM_1 PF00076.17 EWM26701.1 - 2e-15 56.1 0.0 3.2e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM26701.1 - 5.5e-14 51.8 0.0 9.5e-14 51.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM26701.1 - 4.1e-09 36.1 0.0 6.4e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HTH_25 PF13413.1 EWM26702.1 - 0.016 14.8 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Pyr_redox_2 PF07992.9 EWM26703.1 - 3.9e-34 118.3 0.8 7e-34 117.4 0.6 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EWM26703.1 - 9.5e-31 106.0 2.1 1.2e-30 105.7 0.2 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EWM26703.1 - 1.1e-14 54.6 1.9 8.4e-14 51.7 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EWM26703.1 - 3e-07 29.6 4.4 0.0016 17.3 1.5 2.4 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.17 EWM26703.1 - 4.8e-07 28.9 4.1 2.6e-06 26.5 1.0 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EWM26703.1 - 0.0018 17.4 1.8 0.0026 16.9 1.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 EWM26703.1 - 0.0092 15.6 0.4 1.8 8.1 0.0 2.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K_oxygenase PF13434.1 EWM26703.1 - 0.016 14.1 0.0 0.046 12.6 0.0 1.7 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) UDPG_MGDP_dh_N PF03721.9 EWM26703.1 - 0.033 13.5 0.0 0.066 12.5 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.12 EWM26703.1 - 0.049 12.7 2.0 0.12 11.4 0.5 2.3 2 0 0 2 2 2 0 Thi4 family DAO PF01266.19 EWM26703.1 - 0.19 10.6 12.1 0.028 13.3 2.6 2.9 3 1 1 4 4 4 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EWM26703.1 - 0.6 10.1 5.8 7.2 6.7 2.5 2.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain PseudoU_synth_2 PF00849.17 EWM26704.1 - 2e-26 92.7 0.0 8.4e-26 90.7 0.0 1.9 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 EWM26704.1 - 0.001 18.4 0.1 0.002 17.5 0.1 1.5 1 0 0 1 1 1 1 S4 domain Shisa PF13908.1 EWM26705.1 - 8.3e-06 26.0 0.7 1.4e-05 25.3 0.5 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Mito_fiss_reg PF05308.6 EWM26705.1 - 5 6.4 7.3 7.6 5.8 5.1 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator adh_short PF00106.20 EWM26706.1 - 2.2e-20 73.2 0.0 3e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EWM26706.1 - 3e-06 27.3 0.0 1.2e-05 25.4 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding adh_short_C2 PF13561.1 EWM26706.1 - 4.4e-06 26.6 0.0 6.8e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EWM26706.1 - 0.0028 17.4 0.0 0.006 16.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase KR PF08659.5 EWM26706.1 - 0.0032 17.1 0.0 0.008 15.8 0.0 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EWM26706.1 - 0.0076 15.7 0.0 0.027 13.8 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EWM26706.1 - 0.033 13.0 0.0 0.05 12.4 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain EGF_2 PF07974.8 EWM26708.1 - 0.00092 19.3 11.5 0.0027 17.8 7.9 1.8 1 0 0 1 1 1 1 EGF-like domain FKBP_C PF00254.23 EWM26709.1 - 2e-17 62.9 0.0 9.8e-17 60.7 0.0 2.0 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase PDZ PF00595.19 EWM26709.1 - 1.1e-05 25.4 0.4 2.6e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) Ank PF00023.25 EWM26710.1 - 2.7e-18 64.7 2.6 8.1e-07 28.5 0.1 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 EWM26710.1 - 7.8e-16 58.2 0.3 8.5e-10 38.8 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EWM26710.1 - 7.1e-14 51.5 2.5 4.9e-07 29.7 0.1 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EWM26710.1 - 2.5e-12 46.9 0.3 1.9e-08 34.5 0.2 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM26710.1 - 1.3e-11 43.5 0.8 0.011 15.9 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Glyco_transf_22 PF03901.12 EWM26712.1 - 5.1e-76 256.3 8.4 7.3e-76 255.8 5.8 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family LmjF365940-deam PF14421.1 EWM26712.1 - 0.00081 18.8 0.0 0.0016 17.8 0.0 1.5 1 0 0 1 1 1 1 A distinct subfamily of CDD/CDA-like deaminases dCMP_cyt_deam_1 PF00383.17 EWM26712.1 - 0.019 14.6 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region Mur_ligase_M PF08245.7 EWM26713.1 - 1.6e-05 25.0 0.0 3.5e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Mur ligase middle domain OGFr_III PF04680.8 EWM26713.1 - 0.088 12.9 0.8 0.24 11.5 0.5 1.8 1 0 0 1 1 1 0 Opioid growth factor receptor repeat DLIC PF05783.6 EWM26714.1 - 1.3e-27 96.6 0.0 4.7e-21 75.0 0.0 3.7 4 0 0 4 4 4 3 Dynein light intermediate chain (DLIC) AAA_16 PF13191.1 EWM26714.1 - 0.0044 17.0 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Ras PF00071.17 EWM26714.1 - 0.022 14.1 0.0 0.23 10.8 0.0 2.1 2 0 0 2 2 2 0 Ras family TLD PF07534.11 EWM26715.1 - 6.8e-30 103.8 0.7 4.3e-14 52.6 0.0 2.5 2 0 0 2 2 2 2 TLD IlvC PF01450.14 EWM26715.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain DUF1211 PF06736.6 EWM26716.1 - 3.2e-11 43.2 1.2 2.4e-09 37.2 0.0 3.3 3 1 0 3 3 3 2 Protein of unknown function (DUF1211) DUF1211 PF06736.6 EWM26717.1 - 2.5e-18 66.0 7.3 2.9e-09 36.9 0.0 3.9 3 2 0 3 3 3 2 Protein of unknown function (DUF1211) DUF1211 PF06736.6 EWM26718.1 - 3.6e-10 39.8 0.3 2.2e-09 37.3 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1211) FGGY_C PF02782.11 EWM26719.1 - 1.1e-28 100.2 1.1 1.9e-28 99.4 0.8 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EWM26719.1 - 5.8e-12 45.4 0.0 1.1e-06 28.1 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain ERGIC_N PF13850.1 EWM26719.1 - 0.012 15.6 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Peptidase_S49 PF01343.13 EWM26720.1 - 5.1e-56 188.7 0.0 5e-37 127.0 0.0 2.3 2 0 0 2 2 2 2 Peptidase family S49 ECH PF00378.15 EWM26720.1 - 0.037 13.1 2.0 0.46 9.5 0.1 2.9 3 0 0 3 3 3 0 Enoyl-CoA hydratase/isomerase family Adenyl_transf PF04439.7 EWM26720.1 - 0.18 10.7 0.0 0.3 10.0 0.0 1.2 1 0 0 1 1 1 0 Streptomycin adenylyltransferase CLP_protease PF00574.18 EWM26720.1 - 0.26 10.9 0.1 0.63 9.6 0.0 1.5 1 0 0 1 1 1 0 Clp protease Ribosomal_L22 PF00237.14 EWM26721.1 - 4.9e-21 74.6 0.3 6.7e-21 74.2 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DndB PF14072.1 EWM26722.1 - 0.0003 20.0 0.3 0.0017 17.5 0.0 2.1 1 1 1 2 2 2 1 DNA-sulfur modification-associated DUF262 PF03235.9 EWM26722.1 - 0.00045 20.2 0.0 0.00073 19.5 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function DUF262 ParBc PF02195.13 EWM26722.1 - 0.0061 16.6 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 ParB-like nuclease domain AviRa PF11599.3 EWM26722.1 - 0.083 11.8 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Glyco_trans_2_3 PF13632.1 EWM26723.1 - 2.6e-22 79.5 4.7 2.6e-22 79.5 3.2 3.6 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EWM26723.1 - 3.3e-14 53.2 0.0 6.2e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 EST1_DNA_bind PF10373.4 EWM26724.1 - 1.6e-36 125.9 0.0 6.9e-36 123.8 0.0 1.8 1 1 1 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.4 EWM26724.1 - 2.3e-10 40.5 2.3 9.3e-06 25.6 0.1 2.5 1 1 1 2 2 2 2 Telomerase activating protein Est1 TPR_11 PF13414.1 EWM26724.1 - 0.0016 18.0 0.0 0.0048 16.5 0.0 1.8 1 1 0 1 1 1 1 TPR repeat DUF2280 PF10045.4 EWM26724.1 - 0.11 12.3 0.2 0.34 10.8 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2280) Branch PF02485.16 EWM26725.1 - 5.6e-13 48.6 0.0 1.4e-12 47.2 0.0 1.6 2 0 0 2 2 2 1 Core-2/I-Branching enzyme Entericidin PF08085.6 EWM26725.1 - 0.13 12.0 1.6 0.42 10.4 1.1 1.9 1 0 0 1 1 1 0 Entericidin EcnA/B family SCO1-SenC PF02630.9 EWM26726.1 - 2e-26 92.6 0.0 2.6e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.1 EWM26726.1 - 0.013 15.5 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like NAD_binding_1 PF00175.16 EWM26726.1 - 0.092 13.3 0.0 0.27 11.7 0.0 1.9 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain TPR_2 PF07719.12 EWM26728.1 - 1.9e-05 24.2 3.1 0.0016 18.1 0.9 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EWM26728.1 - 0.016 14.8 3.9 0.88 9.2 0.8 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EWM26728.1 - 0.096 12.3 3.9 0.2 11.3 1.5 2.3 2 1 1 3 3 3 0 TPR repeat PPR_2 PF13041.1 EWM26729.1 - 4.9e-62 205.7 2.0 5.1e-07 29.5 0.0 13.9 7 5 7 14 14 14 12 PPR repeat family PPR_3 PF13812.1 EWM26729.1 - 6.8e-53 172.5 26.0 0.0013 18.7 0.0 16.3 16 0 0 16 16 16 14 Pentatricopeptide repeat domain PPR PF01535.15 EWM26729.1 - 1.1e-39 131.6 24.8 7.8e-05 22.3 0.0 16.4 17 1 0 17 17 17 10 PPR repeat PPR_1 PF12854.2 EWM26729.1 - 2e-27 94.3 13.0 0.015 14.7 0.0 13.1 13 0 0 13 13 13 8 PPR repeat Apc3 PF12895.2 EWM26729.1 - 4.1e-09 36.4 1.5 0.079 13.1 0.0 5.5 4 2 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 Clathrin PF00637.15 EWM26729.1 - 0.0032 17.0 0.4 33 4.0 0.0 5.6 6 2 1 7 7 7 0 Region in Clathrin and VPS ECSIT PF06239.6 EWM26729.1 - 0.068 12.0 0.0 4.9 5.9 0.0 3.3 3 0 0 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway TPR_12 PF13424.1 EWM26729.1 - 0.2 11.6 7.1 2.4 8.1 0.0 5.6 5 3 1 6 6 6 0 Tetratricopeptide repeat PPR_2 PF13041.1 EWM26730.1 - 6.2e-62 205.3 2.0 5.2e-07 29.5 0.0 13.9 7 5 7 14 14 14 12 PPR repeat family PPR_3 PF13812.1 EWM26730.1 - 8.4e-53 172.2 26.0 0.0014 18.7 0.0 16.3 16 0 0 16 16 16 14 Pentatricopeptide repeat domain PPR PF01535.15 EWM26730.1 - 1.3e-39 131.4 24.8 7.9e-05 22.3 0.0 16.4 17 1 0 17 17 17 10 PPR repeat PPR_1 PF12854.2 EWM26730.1 - 2.3e-27 94.1 13.0 0.016 14.7 0.0 13.0 13 0 0 13 13 13 8 PPR repeat Apc3 PF12895.2 EWM26730.1 - 4.6e-09 36.3 1.5 0.08 13.0 0.0 5.5 4 2 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 Clathrin PF00637.15 EWM26730.1 - 0.0034 16.9 0.4 34 4.0 0.0 5.6 6 2 1 7 7 7 0 Region in Clathrin and VPS ECSIT PF06239.6 EWM26730.1 - 0.071 11.9 0.0 4.9 5.9 0.0 3.3 3 0 0 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway TPR_12 PF13424.1 EWM26730.1 - 0.22 11.4 7.2 2.4 8.1 0.0 5.6 5 3 1 6 6 6 0 Tetratricopeptide repeat FAD_binding_2 PF00890.19 EWM26732.1 - 1.9e-72 244.4 5.5 2.9e-72 243.8 3.8 1.3 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EWM26732.1 - 7.6e-09 35.5 2.4 1.4e-08 34.5 1.7 1.5 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EWM26732.1 - 2e-08 34.3 0.1 0.00036 20.4 0.1 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EWM26732.1 - 4.3e-08 32.4 0.4 9.5e-08 31.3 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EWM26732.1 - 3.4e-05 22.8 2.6 0.00017 20.5 0.0 2.8 3 0 0 3 3 3 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EWM26732.1 - 0.00065 18.7 0.1 0.0013 17.7 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.2 EWM26732.1 - 0.00084 18.5 1.7 0.0018 17.4 1.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EWM26732.1 - 0.0043 16.1 0.5 0.03 13.4 0.1 2.5 2 1 1 3 3 3 1 Thi4 family FAD_binding_3 PF01494.14 EWM26732.1 - 0.0088 15.1 0.1 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain PE PF00934.15 EWM26732.1 - 0.038 14.0 0.5 1.7 8.7 0.0 3.0 2 1 0 2 2 2 0 PE family CPSase_L_chain PF00289.17 EWM26732.1 - 0.095 12.8 0.2 0.41 10.7 0.0 2.2 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain HI0933_like PF03486.9 EWM26732.1 - 0.23 9.8 1.6 0.34 9.3 0.1 2.0 3 0 0 3 3 3 0 HI0933-like protein ABC1 PF03109.11 EWM26733.1 - 2.5e-34 117.8 0.0 7.2e-34 116.3 0.0 1.8 2 0 0 2 2 2 1 ABC1 family FAD_binding_6 PF00970.19 EWM26734.1 - 0.0017 18.4 0.0 0.0031 17.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain PAT1 PF09770.4 EWM26735.1 - 9.7 4.2 38.3 14 3.7 26.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PAT1 PF09770.4 EWM26736.1 - 9.5 4.3 38.3 14 3.7 26.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PAD_porph PF04371.10 EWM26737.1 - 7.3e-104 347.3 0.0 9e-104 347.0 0.0 1.1 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase UPF0220 PF05255.6 EWM26737.1 - 0.23 10.7 0.2 0.35 10.1 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0220) Pkinase PF00069.20 EWM26738.1 - 1.3e-50 171.9 0.0 2e-50 171.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM26738.1 - 8.9e-48 162.6 0.0 1.3e-47 162.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EWM26738.1 - 3.2e-06 27.0 0.0 0.0001 22.1 0.0 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family PIP49_C PF12260.3 EWM26738.1 - 0.0054 16.1 0.0 0.013 14.8 0.0 1.6 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Spc97_Spc98 PF04130.8 EWM26739.1 - 1.6e-97 327.0 0.0 2.4e-97 326.4 0.0 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family Myb_DNA-binding PF00249.26 EWM26740.1 - 4e-06 26.7 0.2 6.7e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain PRAI PF00697.17 EWM26740.1 - 0.01 15.3 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase CgtA PF06306.6 EWM26740.1 - 0.14 11.3 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Beta-1,4-N-acetylgalactosaminyltransferase (CgtA) DUF669 PF05037.8 EWM26741.1 - 0.0058 16.5 0.1 0.0074 16.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF669) zf-C3HC4_2 PF13923.1 EWM26742.1 - 3.5e-09 36.5 5.4 5.8e-09 35.8 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EWM26742.1 - 2.9e-07 30.1 5.8 6.7e-07 29.0 4.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EWM26742.1 - 3.1e-07 29.9 3.8 5e-07 29.2 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EWM26742.1 - 2.1e-06 27.5 4.9 3.8e-06 26.6 3.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EWM26742.1 - 2.3e-06 27.1 3.4 3.9e-06 26.4 2.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EWM26742.1 - 0.0015 18.2 4.7 0.0026 17.4 3.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EWM26742.1 - 0.0093 16.0 2.8 0.039 14.0 2.0 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger DUF2685 PF10886.3 EWM26742.1 - 0.015 15.3 1.3 0.015 15.3 0.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2685) zf-RING_6 PF14835.1 EWM26742.1 - 0.049 13.4 1.9 0.095 12.5 1.3 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EWM26742.1 - 0.14 11.9 2.1 0.31 10.7 1.4 1.6 1 0 0 1 1 1 0 RING-type zinc-finger DUF1272 PF06906.6 EWM26742.1 - 0.23 11.3 2.6 0.54 10.1 1.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_4 PF14570.1 EWM26742.1 - 0.24 10.9 5.2 0.59 9.7 3.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF3727 PF12527.3 EWM26743.1 - 1.1e-05 25.4 0.4 0.0031 17.5 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF3727) CUE PF02845.11 EWM26745.1 - 0.025 14.0 0.0 0.074 12.5 0.0 1.9 1 0 0 1 1 1 0 CUE domain S1 PF00575.18 EWM26746.1 - 6.1e-10 39.0 1.6 6.9e-09 35.6 1.2 2.6 3 0 0 3 3 3 1 S1 RNA binding domain AMP-binding PF00501.23 EWM26747.1 - 1.1e-48 165.6 0.0 1.6e-48 165.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PQQ_2 PF13360.1 EWM26747.1 - 1.2e-19 70.7 0.0 1e-12 48.0 0.0 2.6 1 1 2 3 3 3 3 PQQ-like domain PQQ_3 PF13570.1 EWM26747.1 - 1.2e-15 57.1 0.2 0.0019 18.4 0.0 5.8 6 0 0 6 6 6 4 PQQ-like domain PQQ PF01011.16 EWM26747.1 - 6.5e-13 47.5 0.1 0.00066 19.0 0.0 5.3 5 0 0 5 5 5 2 PQQ enzyme repeat AMP-binding PF00501.23 EWM26748.1 - 3.5e-23 81.6 0.0 5.3e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PQQ_2 PF13360.1 EWM26748.1 - 4.8e-20 72.0 0.0 7.1e-13 48.5 0.0 2.7 1 1 2 3 3 3 3 PQQ-like domain PQQ_3 PF13570.1 EWM26748.1 - 2.6e-16 59.3 0.2 0.0014 18.8 0.0 5.9 6 0 0 6 6 6 4 PQQ-like domain PQQ PF01011.16 EWM26748.1 - 1.9e-13 49.1 0.1 0.00048 19.5 0.0 5.2 5 0 0 5 5 5 3 PQQ enzyme repeat AMP-binding PF00501.23 EWM26749.1 - 1.1e-48 165.6 0.0 1.6e-48 165.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PQQ_2 PF13360.1 EWM26749.1 - 1.2e-19 70.7 0.0 1e-12 48.0 0.0 2.6 1 1 2 3 3 3 3 PQQ-like domain PQQ_3 PF13570.1 EWM26749.1 - 1.2e-15 57.1 0.2 0.0019 18.4 0.0 5.8 6 0 0 6 6 6 4 PQQ-like domain PQQ PF01011.16 EWM26749.1 - 6.5e-13 47.5 0.1 0.00066 19.0 0.0 5.3 5 0 0 5 5 5 2 PQQ enzyme repeat tRNA-synt_2c PF01411.14 EWM26750.1 - 1.4e-199 664.0 0.0 1.7e-199 663.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EWM26750.1 - 2.8e-14 52.7 0.0 6.1e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TSC22 PF01166.13 EWM26751.1 - 0.04 13.8 2.6 0.1 12.5 0.3 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF972 PF06156.8 EWM26751.1 - 0.26 11.6 13.1 0.77 10.1 1.5 3.0 2 1 2 4 4 4 0 Protein of unknown function (DUF972) Spc7 PF08317.6 EWM26751.1 - 5.3 5.6 14.3 11 4.6 9.9 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein CRAL_TRIO PF00650.15 EWM26753.1 - 2.3e-27 95.4 0.0 3e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain zf-BED PF02892.10 EWM26753.1 - 0.06 13.1 0.1 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 BED zinc finger Copine PF07002.11 EWM26754.1 - 1.5e-31 109.0 0.0 2.7e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.4 EWM26754.1 - 0.014 15.2 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 vWA found in TerF C terminus zf-C2H2_2 PF12756.2 EWM26755.1 - 8.2e-30 102.9 16.3 6.4e-24 83.9 2.5 3.3 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EWM26755.1 - 3.4e-09 36.5 26.3 3.1e-07 30.3 1.5 4.5 4 1 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EWM26755.1 - 3.4e-08 33.3 23.3 7.9e-08 32.2 2.4 3.8 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EWM26755.1 - 0.0036 17.5 1.7 0.0036 17.5 1.2 3.9 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EWM26755.1 - 0.0038 17.4 1.3 0.0038 17.4 0.9 4.5 4 0 0 4 4 4 1 C2H2-type zinc finger HNH PF01844.18 EWM26755.1 - 0.043 13.7 4.2 17 5.4 0.0 3.6 3 0 0 3 3 3 0 HNH endonuclease zf-C2HC_2 PF13913.1 EWM26755.1 - 0.13 11.9 6.4 0.37 10.5 0.0 3.0 3 0 0 3 3 3 0 zinc-finger of a C2HC-type AKAP95 PF04988.7 EWM26755.1 - 0.15 11.7 3.9 2.8 7.7 0.2 3.3 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) Rft-1 PF04506.8 EWM26756.1 - 7.1e-65 219.4 5.5 2.4e-35 121.9 0.4 3.8 2 1 0 2 2 2 2 Rft protein Polysacc_synt_C PF14667.1 EWM26756.1 - 2.3e-05 24.2 4.9 2.3e-05 24.2 3.4 4.4 4 0 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain DUF2101 PF09874.4 EWM26756.1 - 5.4 6.4 8.3 1.7 8.0 0.3 2.9 2 1 1 3 3 3 0 Predicted membrane protein (DUF2101) DUF630 PF04783.7 EWM26757.1 - 0.02 14.8 0.4 0.042 13.7 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF630) Pkinase PF00069.20 EWM26758.1 - 3.8e-72 242.5 0.0 4.7e-72 242.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM26758.1 - 5.7e-31 107.5 0.0 8.7e-31 106.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EWM26758.1 - 0.0036 16.3 0.4 0.025 13.6 0.3 2.3 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EWM26758.1 - 0.031 13.9 0.1 0.095 12.4 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EWM26758.1 - 0.039 12.9 0.0 0.074 11.9 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.6 EWM26758.1 - 0.057 12.2 0.2 0.099 11.4 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.15 EWM26758.1 - 0.14 11.7 0.1 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RAMP4 PF06624.7 EWM26759.1 - 4.7e-26 90.1 0.2 6.2e-26 89.7 0.1 1.2 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 HSP20 PF00011.16 EWM26760.1 - 1.3e-21 76.3 1.8 1.7e-21 75.9 1.3 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family PPR PF01535.15 EWM26761.1 - 0.012 15.5 1.0 5.9 7.0 0.0 4.6 5 0 0 5 5 5 0 PPR repeat ATP13 PF12921.2 EWM26761.1 - 0.026 13.8 0.0 0.11 11.8 0.0 2.0 1 1 0 1 1 1 0 Mitochondrial ATPase expression TPR_16 PF13432.1 EWM26761.1 - 0.3 11.7 19.6 6.7 7.5 0.3 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.1 EWM26761.1 - 0.49 10.3 3.6 23 4.9 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EWM26761.1 - 0.62 10.4 9.2 0.59 10.5 0.2 4.2 4 1 1 5 5 5 0 Tetratricopeptide repeat PPR_3 PF13812.1 EWM26761.1 - 1.6 9.2 6.8 1e+02 3.5 0.0 5.9 7 0 0 7 7 7 0 Pentatricopeptide repeat domain Tim17 PF02466.14 EWM26762.1 - 1.9e-31 108.7 7.5 2.2e-31 108.5 5.2 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.4 EWM26762.1 - 3 8.0 12.1 0.99 9.5 0.8 2.2 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide ECH PF00378.15 EWM26763.1 - 5.4e-21 74.8 0.0 7.3e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family NDK PF00334.14 EWM26764.1 - 5.8e-53 178.3 0.0 1.1e-52 177.4 0.0 1.4 2 0 0 2 2 2 1 Nucleoside diphosphate kinase CHAD PF05235.9 EWM26765.1 - 0.086 12.3 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 CHAD domain DUF3168 PF11367.3 EWM26765.1 - 0.097 12.8 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3168) MM_CoA_mutase PF01642.17 EWM26766.1 - 3.4e-243 807.4 0.2 4.2e-243 807.1 0.1 1.1 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.14 EWM26766.1 - 6.8e-14 51.7 0.5 1.8e-13 50.3 0.4 1.8 1 0 0 1 1 1 1 B12 binding domain NPR2 PF06218.6 EWM26767.1 - 5e-97 325.3 0.0 6.6e-97 324.9 0.0 1.2 1 0 0 1 1 1 1 Nitrogen permease regulator 2 AAA_22 PF13401.1 EWM26767.1 - 0.033 14.3 0.0 0.073 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain PAS_9 PF13426.1 EWM26768.1 - 3.9e-22 78.5 0.0 1.7e-21 76.5 0.0 1.9 2 0 0 2 2 2 1 PAS domain bZIP_2 PF07716.10 EWM26768.1 - 1.8e-08 34.0 11.5 3.1e-08 33.2 8.0 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EWM26768.1 - 3.7e-08 33.1 8.3 6.6e-08 32.4 5.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor PAS_3 PF08447.6 EWM26768.1 - 4.5e-05 23.4 0.0 7.6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 EWM26768.1 - 0.00036 20.2 0.0 0.0008 19.1 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 EWM26768.1 - 0.014 15.4 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 PAS fold bZIP_Maf PF03131.12 EWM26768.1 - 0.02 15.1 5.3 0.039 14.2 3.7 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor HAP1_N PF04849.8 EWM26768.1 - 0.028 13.3 3.7 0.036 13.0 2.6 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region FlgM PF04316.8 EWM26768.1 - 0.073 13.0 0.0 0.21 11.5 0.0 1.9 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM HSP70 PF00012.15 EWM26769.1 - 3.2e-264 877.4 8.5 3.7e-264 877.2 5.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EWM26769.1 - 3.8e-15 55.3 5.5 6.8e-14 51.2 0.1 3.0 3 0 0 3 3 3 2 MreB/Mbl protein FtsA PF14450.1 EWM26769.1 - 0.00095 19.0 5.1 0.97 9.2 0.0 5.0 3 2 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.11 EWM26769.1 - 0.0049 16.4 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain YfcL PF08891.6 EWM26769.1 - 0.22 11.4 5.7 0.56 10.2 1.1 3.1 3 0 0 3 3 3 0 YfcL protein Acyl-CoA_dh_C PF12806.2 EWM26769.1 - 0.3 10.9 5.5 0.83 9.5 0.4 2.7 2 0 0 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like ATP-synt_B PF00430.13 EWM26769.1 - 0.61 9.8 18.6 0.081 12.7 9.5 2.1 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) DUF4296 PF14129.1 EWM26771.1 - 0.053 13.6 0.8 1.2 9.3 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4296) Cep57_MT_bd PF06657.8 EWM26771.1 - 0.057 13.3 3.8 7.5 6.5 0.6 2.8 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 PRESAN PF09687.5 EWM26771.1 - 0.085 12.9 0.2 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Plasmodium RESA N-terminal PI3_PI4_kinase PF00454.22 EWM26772.1 - 1e-25 90.5 0.0 8.7e-24 84.2 0.0 2.7 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PH PF00169.24 EWM26772.1 - 2.6e-11 43.6 0.0 5.7e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EWM26772.1 - 0.00057 20.1 2.0 0.036 14.3 1.4 2.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EWM26772.1 - 0.0017 18.4 0.0 0.0051 16.8 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.1 EWM26772.1 - 0.016 15.3 0.2 0.12 12.5 0.2 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain DUF2518 PF10726.4 EWM26773.1 - 0.083 12.4 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of function (DUF2518) Kinesin PF00225.18 EWM26774.1 - 7.1e-110 366.8 0.3 2.1e-109 365.2 0.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain DUF2968 PF11180.3 EWM26774.1 - 0.0063 15.9 6.7 0.0063 15.9 4.7 4.7 3 1 1 4 4 4 1 Protein of unknown function (DUF2968) Polysacc_deac_1 PF01522.16 EWM26774.1 - 0.016 14.8 0.4 0.046 13.3 0.3 1.8 1 0 0 1 1 1 0 Polysaccharide deacetylase Bacillus_HBL PF05791.6 EWM26774.1 - 1.8 7.8 17.3 3.9 6.8 3.7 4.1 3 1 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) LCM PF04072.9 EWM26775.1 - 1.7e-34 119.0 0.1 4.6e-34 117.5 0.1 1.7 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase COG5 PF10392.4 EWM26776.1 - 3.3e-13 49.7 2.2 4.8e-13 49.1 0.3 2.2 2 0 0 2 2 2 1 Golgi transport complex subunit 5 DUF2450 PF10475.4 EWM26776.1 - 0.00034 19.5 1.7 0.00066 18.6 1.2 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) HALZ PF02183.13 EWM26776.1 - 0.055 13.1 0.5 0.21 11.3 0.4 2.0 1 0 0 1 1 1 0 Homeobox associated leucine zipper HEAT_2 PF13646.1 EWM26777.1 - 4.1e-46 155.1 8.7 1.1e-14 54.5 0.0 4.0 2 2 2 4 4 4 4 HEAT repeats HEAT_PBS PF03130.11 EWM26777.1 - 1e-23 81.3 8.1 0.00025 21.2 0.0 6.5 7 0 0 7 7 7 5 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 EWM26777.1 - 1.3e-11 44.5 3.5 0.018 15.4 0.1 5.3 3 2 2 5 5 5 3 HEAT-like repeat HEAT PF02985.17 EWM26777.1 - 4.3e-10 38.8 1.4 0.013 15.5 0.0 5.7 5 0 0 5 5 5 3 HEAT repeat T2SK PF03934.8 EWM26777.1 - 0.016 14.3 0.2 0.043 12.9 0.0 1.7 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein K TPR_15 PF13429.1 EWM26777.1 - 0.09 11.8 0.1 0.25 10.3 0.0 1.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EWM26777.1 - 0.098 13.3 1.8 0.73 10.5 0.0 3.2 3 2 1 4 4 4 0 Tetratricopeptide repeat tRNA-synt_1c PF00749.16 EWM26778.1 - 6.1e-96 320.7 0.1 9.8e-96 320.0 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EWM26778.1 - 1.9e-36 125.3 0.0 3.3e-36 124.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 EWM26778.1 - 4.5e-10 39.9 0.2 4.5e-10 39.9 0.1 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain WHEP-TRS PF00458.15 EWM26778.1 - 1.6e-07 30.8 0.3 1.6e-07 30.8 0.2 2.0 2 0 0 2 2 2 1 WHEP-TRS domain GST_C PF00043.20 EWM26778.1 - 6.9e-06 25.9 0.3 0.00013 21.9 0.0 2.9 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EWM26778.1 - 5.6e-05 22.9 0.3 0.00014 21.7 0.2 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.14 EWM26778.1 - 0.11 11.6 4.0 0.084 11.9 0.3 2.3 2 1 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain G0-G1_switch_2 PF15103.1 EWM26778.1 - 1.5 9.0 4.5 40 4.5 0.0 2.7 2 1 0 2 2 2 0 G0/G1 switch protein 2 Hydrolase_6 PF13344.1 EWM26779.1 - 1.6e-19 69.6 0.0 5.1e-19 68.0 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EWM26779.1 - 7.1e-14 51.2 0.1 2.1e-12 46.5 0.0 2.6 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 EWM26779.1 - 0.014 15.8 0.0 1 9.7 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EWM26779.1 - 0.046 13.9 0.2 28 4.8 0.0 3.5 3 1 0 3 3 3 0 Haloacid dehalogenase-like hydrolase UCH PF00443.24 EWM26780.1 - 7.3e-18 64.6 0.0 8.4e-18 64.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EWM26780.1 - 0.013 14.9 0.1 0.016 14.6 0.1 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase RabGAP-TBC PF00566.13 EWM26781.1 - 1.9e-50 171.3 0.1 3.9e-26 91.8 0.2 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Ribosomal_L19 PF01245.15 EWM26783.1 - 1.4e-18 66.6 0.0 2e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L19 UQ_con PF00179.21 EWM26784.1 - 9.5e-27 93.1 0.1 1.3e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EWM26784.1 - 2.6e-07 30.4 0.0 4.3e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EWM26784.1 - 0.0012 18.7 0.0 0.0022 17.8 0.0 1.3 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 EWM26784.1 - 0.036 13.7 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 UEV domain UFC1 PF08694.6 EWM26784.1 - 0.096 12.1 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 ATG11 PF10377.4 EWM26785.1 - 1.3e-18 67.0 0.0 4e-18 65.5 0.0 1.8 2 0 0 2 2 2 1 Autophagy-related protein 11 APG17 PF04108.7 EWM26785.1 - 0.00027 19.8 0.2 0.00079 18.3 0.2 1.8 1 0 0 1 1 1 1 Autophagy protein Apg17 Jnk-SapK_ap_N PF09744.4 EWM26785.1 - 0.00091 19.2 2.6 0.035 14.1 0.0 3.0 2 0 0 2 2 2 1 JNK_SAPK-associated protein-1 YjcZ PF13990.1 EWM26785.1 - 0.11 11.6 3.4 0.42 9.7 0.4 2.3 2 0 0 2 2 2 0 YjcZ-like protein Mto2_bdg PF12808.2 EWM26785.1 - 0.23 11.6 6.5 3.5 7.8 0.2 3.5 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region SOG2 PF10428.4 EWM26785.1 - 0.61 8.6 7.1 1.2 7.7 4.9 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein SlyX PF04102.7 EWM26785.1 - 4.1 7.8 9.5 4.2 7.8 0.0 5.1 7 0 0 7 7 7 0 SlyX Glyco_tran_28_C PF04101.11 EWM26786.1 - 2.5e-24 85.8 0.0 7.3e-22 77.7 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EWM26786.1 - 1.2e-05 24.6 0.0 1.7e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 1 CBM49 PF09478.5 EWM26787.1 - 0.0011 19.0 0.3 3.7 7.7 0.0 4.6 5 1 0 5 5 5 2 Carbohydrate binding domain CBM49 TPR_11 PF13414.1 EWM26788.1 - 4.7e-12 45.3 4.7 4.2e-08 32.7 0.1 2.7 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EWM26788.1 - 1.2e-10 40.4 3.0 0.016 15.0 0.5 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EWM26788.1 - 2.2e-09 36.4 2.4 0.0055 16.2 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat FKBP_C PF00254.23 EWM26788.1 - 4.5e-08 32.9 0.0 8.5e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_16 PF13432.1 EWM26788.1 - 7.4e-08 32.8 4.8 7e-06 26.5 0.7 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EWM26788.1 - 0.00022 21.0 1.2 0.026 14.4 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EWM26788.1 - 0.0007 20.0 3.1 3.3 8.6 0.9 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EWM26788.1 - 0.0016 18.7 5.3 0.032 14.5 0.9 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EWM26788.1 - 0.0053 16.4 0.2 4.2 7.4 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EWM26788.1 - 0.0058 16.7 0.1 6.7 7.1 0.0 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat DUF3449 PF11931.3 EWM26788.1 - 0.014 14.9 2.0 0.023 14.1 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) TPR_8 PF13181.1 EWM26788.1 - 0.047 13.4 0.6 11 6.0 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Bromodomain PF00439.20 EWM26789.1 - 9.2e-27 92.7 0.0 6.2e-13 48.4 0.0 2.5 2 0 0 2 2 2 2 Bromodomain DNMT1-RFD PF12047.3 EWM26789.1 - 2.8e-09 36.8 0.0 6.2e-05 22.7 0.0 2.7 2 0 0 2 2 2 2 Cytosine specific DNA methyltransferase replication foci domain WHIM2 PF15613.1 EWM26789.1 - 5e-06 26.2 0.2 1.3e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 Auxin_resp PF06507.8 EWM26789.1 - 0.027 14.3 0.0 0.07 12.9 0.0 1.6 1 0 0 1 1 1 0 Auxin response factor Bromodomain PF00439.20 EWM26790.1 - 9.2e-27 92.7 0.0 6.2e-13 48.4 0.0 2.5 2 0 0 2 2 2 2 Bromodomain DNMT1-RFD PF12047.3 EWM26790.1 - 2.8e-09 36.8 0.0 6.2e-05 22.7 0.0 2.7 2 0 0 2 2 2 2 Cytosine specific DNA methyltransferase replication foci domain WHIM2 PF15613.1 EWM26790.1 - 5e-06 26.2 0.2 1.3e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 Auxin_resp PF06507.8 EWM26790.1 - 0.027 14.3 0.0 0.07 12.9 0.0 1.6 1 0 0 1 1 1 0 Auxin response factor Yip1 PF04893.12 EWM26791.1 - 3.4e-10 39.6 10.9 5.2e-10 39.0 7.6 1.3 1 0 0 1 1 1 1 Yip1 domain Rib_5-P_isom_A PF06026.9 EWM26792.1 - 1.3e-42 145.0 0.1 1.8e-42 144.5 0.1 1.2 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Sugar-bind PF04198.8 EWM26792.1 - 0.035 13.0 0.0 0.052 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain CbiC PF02570.10 EWM26792.1 - 0.094 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Precorrin-8X methylmutase Rib_5-P_isom_A PF06026.9 EWM26793.1 - 1.1e-42 145.3 0.1 1.4e-42 144.9 0.1 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Lectin_C PF00059.16 EWM26794.1 - 9.1e-09 35.9 0.2 4.9e-08 33.5 0.0 2.3 2 0 0 2 2 2 1 Lectin C-type domain WSC PF01822.14 EWM26794.1 - 3.1e-06 27.0 11.2 3.1e-06 27.0 7.7 2.6 3 0 0 3 3 3 1 WSC domain SH2 PF00017.19 EWM26795.1 - 5.3e-05 22.9 0.0 0.00012 21.7 0.0 1.5 1 0 0 1 1 1 1 SH2 domain Amidohydro_2 PF04909.9 EWM26796.1 - 0.093 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Amidohydrolase tRNA-synt_1c PF00749.16 EWM26798.1 - 7.7e-103 343.4 0.0 9.5e-103 343.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Dynein_light PF01221.13 EWM26799.1 - 1.9e-44 149.5 1.1 2.8e-44 149.0 0.8 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 UCH PF00443.24 EWM26799.1 - 0.03 13.4 0.0 0.038 13.1 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase GCV_H PF01597.14 EWM26801.1 - 2.3e-10 40.1 0.0 3.5e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage H-protein Arf PF00025.16 EWM26802.1 - 1.3e-78 262.2 0.1 1.5e-78 262.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EWM26802.1 - 6.2e-13 48.4 0.0 6.8e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EWM26802.1 - 9.3e-13 47.7 0.0 1.1e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EWM26802.1 - 4.5e-11 42.0 0.9 8.1e-08 31.3 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EWM26802.1 - 5.1e-10 38.8 0.0 5.7e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EWM26802.1 - 2e-08 34.7 0.0 2.6e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EWM26802.1 - 3.2e-05 23.8 0.0 4.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EWM26802.1 - 0.0069 15.4 0.1 0.0089 15.1 0.1 1.3 1 1 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 EWM26802.1 - 0.018 14.5 0.1 0.14 11.6 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 EWM26802.1 - 0.033 14.0 0.1 0.061 13.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain Complex1_LYR PF05347.10 EWM26803.1 - 1.5e-12 47.0 0.7 2.9e-12 46.1 0.2 1.7 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EWM26803.1 - 9.7e-11 41.7 0.2 1.9e-10 40.8 0.1 1.5 1 0 0 1 1 1 1 Complex1_LYR-like DUF1214 PF06742.6 EWM26805.1 - 1.4e-05 25.5 0.2 0.00026 21.4 0.0 3.2 4 0 0 4 4 4 1 Protein of unknown function (DUF1214) Band_7 PF01145.20 EWM26807.1 - 1.6e-20 73.7 1.2 2.6e-20 73.0 0.9 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.3 EWM26807.1 - 0.058 13.4 0.9 0.096 12.7 0.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 2 ThiF PF00899.16 EWM26809.1 - 1.2e-28 99.5 0.0 1.7e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EWM26809.1 - 0.0048 17.0 0.1 0.023 14.7 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GTP_EFTU PF00009.22 EWM26810.1 - 1.2e-59 200.9 0.0 1.9e-59 200.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EWM26810.1 - 1.2e-26 92.3 0.1 5.9e-26 90.1 0.0 2.3 3 0 0 3 3 3 1 Elongation Factor G, domain II EFG_C PF00679.19 EWM26810.1 - 6.1e-23 80.4 0.0 1.1e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.13 EWM26810.1 - 4.7e-06 26.1 0.0 1.3e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.20 EWM26810.1 - 2e-05 24.6 0.1 5.4e-05 23.2 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EWM26810.1 - 0.00013 21.8 0.1 0.00026 20.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EWM26810.1 - 0.042 12.9 0.0 0.071 12.1 0.0 1.2 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.13 EWM26810.1 - 0.15 11.3 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B Miro PF08477.8 EWM26810.1 - 0.26 11.8 0.0 0.46 10.9 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein Chloroa_b-bind PF00504.16 EWM26813.1 - 1.9e-40 138.6 0.0 2.5e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Trypsin PF00089.21 EWM26814.1 - 4.6e-11 42.7 0.1 4.5e-10 39.4 0.0 2.0 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 EWM26814.1 - 3.4e-10 39.9 0.0 6.2e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Flavi_glycop_C PF02832.11 EWM26814.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Flavivirus glycoprotein, immunoglobulin-like domain WLM PF08325.5 EWM26815.1 - 7.4e-32 110.7 0.0 1.2e-31 110.0 0.0 1.6 1 1 0 1 1 1 1 WLM domain PUB PF09409.5 EWM26815.1 - 1.2e-13 50.5 0.0 3.2e-13 49.2 0.0 1.7 2 0 0 2 2 2 1 PUB domain ubiquitin PF00240.18 EWM26815.1 - 0.00024 20.4 0.1 0.00049 19.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EWM26815.1 - 0.0008 19.1 0.6 0.0035 17.1 0.3 2.2 2 0 0 2 2 2 1 UBA/TS-N domain DUF45 PF01863.12 EWM26815.1 - 0.044 13.5 0.9 0.1 12.3 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF45 ABC1 PF03109.11 EWM26816.1 - 2.9e-23 82.1 0.0 6e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 EWM26816.1 - 3e-05 23.8 2.6 0.00091 19.0 0.3 3.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.17 EWM26816.1 - 0.00012 21.5 0.0 0.00044 19.6 0.0 1.8 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.20 EWM26816.1 - 0.05 12.7 0.1 0.11 11.5 0.0 1.5 2 0 0 2 2 2 0 Protein kinase domain Pkinase_Tyr PF07714.12 EWM26816.1 - 0.057 12.4 0.0 0.16 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein tyrosine kinase WaaY PF06176.6 EWM26816.1 - 0.17 11.0 0.0 0.32 10.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) GPI-anchored PF10342.4 EWM26817.1 - 0.0098 16.3 2.4 0.01 16.3 0.2 2.1 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family FtsJ PF01728.14 EWM26818.1 - 4e-46 157.2 0.0 4.9e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase FtsJ PF01728.14 EWM26819.1 - 7.1e-38 130.4 0.0 9e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Thioredoxin_8 PF13905.1 EWM26820.1 - 8.7e-25 86.6 0.0 1.1e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 EWM26820.1 - 3.3e-10 39.6 0.0 4.2e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.1 EWM26820.1 - 4.1e-09 36.6 0.0 6.5e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.15 EWM26820.1 - 1.6e-08 34.1 0.0 4.8e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin AhpC-TSA PF00578.16 EWM26820.1 - 3.2e-08 33.2 0.0 5e-08 32.6 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.1 EWM26820.1 - 1.6e-05 24.8 0.0 0.00014 21.7 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EWM26820.1 - 0.0008 18.9 0.0 0.0022 17.5 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin TraF PF13728.1 EWM26820.1 - 0.01 15.3 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein DUF953 PF06110.6 EWM26820.1 - 0.064 12.6 0.1 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Glutaredoxin PF00462.19 EWM26820.1 - 0.1 12.5 0.1 0.23 11.4 0.0 1.7 1 1 0 1 1 1 0 Glutaredoxin Bromodomain PF00439.20 EWM26822.1 - 4.8e-19 68.0 0.0 1.2e-18 66.7 0.0 1.7 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 EWM26822.1 - 3.9e-10 39.7 0.7 8.9e-10 38.6 0.5 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EWM26822.1 - 5.1e-10 39.2 2.9 5.8e-10 39.0 0.2 2.5 3 0 0 3 3 3 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EWM26822.1 - 2.9e-06 27.3 0.1 6.6e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EWM26822.1 - 0.08 12.7 0.4 0.16 11.8 0.1 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Jnk-SapK_ap_N PF09744.4 EWM26823.1 - 0.12 12.3 0.2 0.12 12.3 0.1 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 IncA PF04156.9 EWM26823.1 - 0.74 9.3 5.8 2.2 7.8 0.4 2.3 2 0 0 2 2 2 0 IncA protein FlxA PF14282.1 EWM26823.1 - 1.6 8.7 15.1 4.1 7.3 1.9 2.5 2 0 0 2 2 2 0 FlxA-like protein PRP1_N PF06424.7 EWM26823.1 - 1.9 8.8 13.1 6.1 7.1 0.3 2.3 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal DAGAT PF03982.8 EWM26824.1 - 2.4e-42 144.6 0.0 3.2e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.16 EWM26824.1 - 0.0012 18.2 0.0 0.0029 17.0 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase DUF3561 PF12084.3 EWM26824.1 - 0.17 11.7 0.2 0.17 11.7 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3561) DAGAT PF03982.8 EWM26825.1 - 2e-29 102.2 0.0 2.7e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.16 EWM26825.1 - 0.0009 18.6 0.0 0.0024 17.3 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase Lectin_C PF00059.16 EWM26828.1 - 3.6e-26 91.8 4.1 2e-09 38.0 0.0 4.7 4 0 0 4 4 4 3 Lectin C-type domain Herpes_UL45 PF05473.7 EWM26828.1 - 1.1e-08 34.7 6.7 0.056 12.8 0.1 3.4 3 0 0 3 3 3 3 UL45 protein WSC PF01822.14 EWM26828.1 - 5.2e-07 29.4 13.3 2.1e-06 27.5 9.2 2.2 1 0 0 1 1 1 1 WSC domain Jacalin PF01419.12 EWM26828.1 - 6.1e-05 22.9 0.3 0.00016 21.5 0.2 1.6 1 0 0 1 1 1 1 Jacalin-like lectin domain Chordopox_A33R PF05966.7 EWM26828.1 - 6.5e-05 21.7 5.0 0.032 12.9 0.0 3.2 3 0 0 3 3 3 2 Chordopoxvirus A33R protein FGF PF00167.13 EWM26828.1 - 0.08 12.7 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Fibroblast growth factor TPR_11 PF13414.1 EWM26829.1 - 3.3e-12 45.8 3.0 3.7e-12 45.7 1.1 1.7 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EWM26829.1 - 5.7e-11 41.5 0.8 4.3e-06 26.1 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EWM26829.1 - 1.1e-08 34.3 3.3 0.00031 20.4 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EWM26829.1 - 3.5e-07 30.7 2.7 0.0014 19.2 0.1 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EWM26829.1 - 5.4e-05 23.4 2.4 0.027 15.0 0.0 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EWM26829.1 - 0.0014 18.5 4.7 0.64 9.9 0.4 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 EWM26829.1 - 0.0026 18.0 0.7 3.5 8.3 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EWM26829.1 - 0.0039 16.8 0.1 7.3 6.6 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EWM26829.1 - 0.01 15.9 1.2 0.017 15.2 0.8 1.4 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 EWM26829.1 - 0.024 14.4 0.1 0.056 13.3 0.1 1.7 1 1 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat DUF3856 PF12968.2 EWM26829.1 - 0.087 12.6 0.3 0.33 10.7 0.2 1.9 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) TPR_7 PF13176.1 EWM26829.1 - 0.092 12.5 4.5 5.5 7.0 0.2 3.2 2 2 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 EWM26829.1 - 0.093 12.6 5.2 0.52 10.1 0.2 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat MIT PF04212.13 EWM26829.1 - 0.11 12.4 2.2 6.1 6.8 1.0 2.9 2 2 0 2 2 2 0 MIT (microtubule interacting and transport) domain BTAD PF03704.12 EWM26829.1 - 0.11 12.8 5.2 0.34 11.2 0.7 2.6 1 1 1 2 2 2 0 Bacterial transcriptional activator domain IBR PF01485.16 EWM26830.1 - 0.0025 17.6 14.8 0.0048 16.7 10.3 1.4 1 0 0 1 1 1 1 IBR domain HMG_CoA_synt_N PF01154.12 EWM26831.1 - 2.9e-80 267.8 0.1 5.5e-80 266.9 0.0 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.5 EWM26831.1 - 2.4e-79 266.7 0.0 4.5e-79 265.8 0.0 1.5 2 0 0 2 2 2 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal ketoacyl-synt PF00109.21 EWM26831.1 - 1.3e-15 57.6 3.7 1.1e-06 28.3 1.7 2.4 1 1 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EWM26831.1 - 1e-07 31.4 10.9 0.00036 20.1 2.2 4.6 3 1 0 3 3 3 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.5 EWM26831.1 - 0.015 15.2 2.8 0.53 10.3 0.0 3.8 4 0 0 4 4 4 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal zf-DHHC PF01529.15 EWM26832.1 - 4.4e-38 130.3 0.4 8.1e-38 129.5 0.3 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Rhodanese PF00581.15 EWM26834.1 - 3e-05 24.3 0.0 0.032 14.5 0.0 2.6 2 0 0 2 2 2 2 Rhodanese-like domain Siva PF05458.7 EWM26835.1 - 7.5e-09 35.3 10.7 1.3e-08 34.5 7.4 1.4 1 0 0 1 1 1 1 Cd27 binding protein (Siva) Sugar_tr PF00083.19 EWM26836.1 - 7.8e-90 301.5 16.0 1.2e-52 179.0 0.9 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EWM26836.1 - 2.2e-17 62.8 29.0 2.2e-17 62.8 20.1 2.2 1 1 0 2 2 2 1 Major Facilitator Superfamily Mon1 PF03164.9 EWM26837.1 - 7.3e-68 229.0 0.0 9.4e-60 202.3 0.0 3.0 2 1 0 2 2 2 2 Trafficking protein Mon1 E3_UbLigase_R4 PF13764.1 EWM26839.1 - 6.2e-99 331.9 0.0 4.9e-49 166.9 0.0 4.2 4 0 0 4 4 4 4 E3 ubiquitin-protein ligase UBR4 ZZ PF00569.12 EWM26839.1 - 3.5e-06 26.4 5.0 3.5e-06 26.4 3.5 3.0 2 1 1 3 3 3 1 Zinc finger, ZZ type PolC_DP2 PF03833.8 EWM26839.1 - 0.38 8.3 2.4 0.74 7.4 1.6 1.3 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Longin PF13774.1 EWM26842.1 - 0.045 13.3 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 Regulated-SNARE-like domain DUF2407_C PF13373.1 EWM26843.1 - 2.4e-22 79.3 0.7 5.2e-22 78.2 0.3 1.7 2 0 0 2 2 2 1 DUF2407 C-terminal domain ubiquitin PF00240.18 EWM26843.1 - 4.7e-05 22.6 0.0 7.5e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EWM26843.1 - 0.0093 16.1 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Proteasome PF00227.21 EWM26844.1 - 2.5e-08 33.4 0.0 6.8e-07 28.7 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit ABC_membrane PF00664.18 EWM26845.1 - 6.9e-102 340.5 21.6 3.1e-56 190.7 0.9 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EWM26845.1 - 1.7e-69 232.3 0.0 5.7e-34 117.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EWM26845.1 - 1.1e-09 38.7 0.0 0.62 9.9 0.0 4.2 3 1 1 4 4 4 3 AAA domain AAA_16 PF13191.1 EWM26845.1 - 1.4e-09 38.1 0.7 0.0016 18.4 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EWM26845.1 - 4.4e-09 35.8 3.2 0.0064 15.7 2.0 4.7 3 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EWM26845.1 - 5.4e-09 35.4 1.2 0.0024 17.3 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EWM26845.1 - 8.6e-09 36.2 0.0 0.0057 17.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EWM26845.1 - 2.1e-08 33.4 0.1 0.00047 19.3 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 APS_kinase PF01583.15 EWM26845.1 - 4e-07 29.8 0.1 0.032 13.9 0.0 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase Zeta_toxin PF06414.7 EWM26845.1 - 1.4e-06 27.5 0.0 0.024 13.7 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_22 PF13401.1 EWM26845.1 - 1.8e-05 24.9 2.0 0.36 10.9 0.0 3.6 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EWM26845.1 - 3.4e-05 24.1 0.0 0.3 11.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EWM26845.1 - 4.5e-05 22.9 0.1 0.81 9.0 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 EWM26845.1 - 7.5e-05 22.6 0.0 0.41 10.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EWM26845.1 - 7.7e-05 22.3 4.0 0.31 10.6 0.1 3.8 4 1 0 4 4 3 2 AAA domain G-alpha PF00503.15 EWM26845.1 - 8.4e-05 21.4 0.0 0.25 9.9 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_5 PF07728.9 EWM26845.1 - 9e-05 22.2 0.2 1.1 8.9 0.0 3.5 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EWM26845.1 - 0.00018 21.5 0.1 0.98 9.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 EWM26845.1 - 0.00031 20.2 0.2 0.51 9.7 0.0 2.7 3 0 0 3 3 2 2 FtsK/SpoIIIE family Sigma54_activ_2 PF14532.1 EWM26845.1 - 0.00035 20.6 0.0 0.17 11.9 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain ABC_ATPase PF09818.4 EWM26845.1 - 0.00049 18.8 4.3 0.13 10.8 0.1 3.1 4 0 0 4 4 4 2 Predicted ATPase of the ABC class SbcCD_C PF13558.1 EWM26845.1 - 0.0009 19.1 4.4 0.84 9.5 0.3 4.0 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EWM26845.1 - 0.0012 18.3 0.1 2.1 7.7 0.0 3.1 3 0 0 3 3 3 2 AAA-like domain DUF87 PF01935.12 EWM26845.1 - 0.0012 18.7 0.1 1 9.1 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 MobB PF03205.9 EWM26845.1 - 0.0014 18.2 0.3 1.5 8.4 0.0 2.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EWM26845.1 - 0.0019 18.1 0.1 0.62 10.0 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF815 PF05673.8 EWM26845.1 - 0.0019 17.1 0.0 1.4 7.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) L51_S25_CI-B8 PF05047.11 EWM26845.1 - 0.0057 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain AAA_14 PF13173.1 EWM26845.1 - 0.0081 16.0 0.0 5 7.0 0.0 3.4 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.18 EWM26845.1 - 0.011 15.5 0.1 1.6 8.4 0.0 2.9 2 1 0 2 2 2 0 Dynamin family KAP_NTPase PF07693.9 EWM26845.1 - 0.018 14.0 0.0 4.6 6.1 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain Sigma54_activat PF00158.21 EWM26845.1 - 0.028 13.8 0.0 3.3 7.1 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Miro PF08477.8 EWM26845.1 - 0.03 14.8 0.0 9.9 6.6 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein PRK PF00485.13 EWM26845.1 - 0.034 13.6 0.0 8.5 5.8 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.7 EWM26845.1 - 0.04 13.5 1.7 7.4 6.1 0.1 3.0 3 0 0 3 3 2 0 NACHT domain UPF0079 PF02367.12 EWM26845.1 - 0.06 12.9 0.1 17 5.0 0.0 3.0 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 EWM26845.1 - 0.067 13.3 0.0 12 6.1 0.0 2.5 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.12 EWM26845.1 - 0.068 12.7 0.1 8.9 5.7 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.17 EWM26845.1 - 0.081 11.7 0.1 9.1 5.0 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Septin PF00735.13 EWM26845.1 - 0.18 10.8 0.1 5.3 5.9 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_23 PF13476.1 EWM26845.1 - 0.2 11.9 0.0 16 5.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain GRIP PF01465.15 EWM26846.1 - 1.7e-07 30.6 0.0 3.8e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 GRIP domain CTD_bind PF04818.8 EWM26848.1 - 0.074 13.3 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase II-binding domain. PRP38 PF03371.10 EWM26848.1 - 0.078 12.5 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 PRP38 family Thoc2 PF11732.3 EWM26848.1 - 0.12 12.1 0.1 0.32 10.8 0.0 1.6 2 0 0 2 2 2 0 Transcription- and export-related complex subunit Retinal PF15449.1 EWM26848.1 - 3 5.3 14.0 4.2 4.9 9.7 1.1 1 0 0 1 1 1 0 Retinal protein UreF PF01730.11 EWM26850.1 - 2.9e-12 46.9 5.7 3.6e-12 46.6 3.3 1.6 1 1 0 1 1 1 1 UreF Vps16_N PF04841.8 EWM26851.1 - 1.7e-46 158.5 0.0 8.7e-22 77.2 0.0 3.1 3 0 0 3 3 3 3 Vps16, N-terminal region Vps16_C PF04840.7 EWM26851.1 - 5.4e-45 153.7 3.7 4.4e-31 108.0 0.6 2.9 2 1 0 2 2 2 2 Vps16, C-terminal region Oligomerisation PF02410.10 EWM26852.1 - 1.5e-15 57.0 0.0 2.6e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Oligomerisation domain Abhydrolase_6 PF12697.2 EWM26853.1 - 1.6e-24 87.0 0.3 2.5e-24 86.4 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM26853.1 - 1.4e-18 67.0 0.0 7.4e-18 64.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EWM26853.1 - 5.4e-05 23.5 0.0 9.3e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.8 EWM26853.1 - 0.0013 18.3 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EWM26853.1 - 0.0014 18.0 0.0 0.14 11.5 0.0 2.5 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 EWM26853.1 - 0.0057 16.2 0.0 0.24 10.9 0.1 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EWM26853.1 - 0.01 15.0 0.0 4.1 6.5 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF1869 PF08956.5 EWM26853.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1869) Abhydrolase_4 PF08386.5 EWM26853.1 - 0.018 14.9 0.0 0.059 13.2 0.0 1.9 1 0 0 1 1 1 0 TAP-like protein DLH PF01738.13 EWM26853.1 - 0.037 13.3 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Tfb4 PF03850.9 EWM26854.1 - 5.1e-69 232.6 0.6 1.5e-54 185.1 2.0 2.1 2 0 0 2 2 2 2 Transcription factor Tfb4 Tfb4 PF03850.9 EWM26855.1 - 7.2e-69 232.1 0.5 1.5e-54 185.1 2.0 2.1 2 0 0 2 2 2 2 Transcription factor Tfb4 Amino_oxidase PF01593.19 EWM26856.1 - 1.7e-20 73.5 0.3 3.2e-14 52.8 0.0 2.8 1 1 2 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EWM26856.1 - 1.3e-13 50.7 0.3 3.8e-13 49.2 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EWM26856.1 - 2.4e-10 39.8 0.7 1.3e-08 34.1 0.5 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EWM26856.1 - 1.2e-08 34.2 1.6 1.5e-07 30.6 0.8 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 EWM26856.1 - 2.7e-06 26.7 0.0 4.1e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EWM26856.1 - 3.4e-05 22.5 0.1 0.0017 16.9 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 EWM26856.1 - 4e-05 23.9 0.7 0.0033 17.7 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EWM26856.1 - 8.7e-05 22.4 0.1 0.0051 16.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EWM26856.1 - 0.00076 18.6 0.2 0.0015 17.6 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EWM26856.1 - 0.0014 17.5 0.1 0.0019 17.1 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 EWM26856.1 - 0.0021 17.1 0.1 0.0038 16.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 EWM26856.1 - 0.017 15.2 0.5 0.26 11.3 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EWM26856.1 - 0.056 12.3 0.0 0.14 11.0 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 EWM26856.1 - 0.089 12.5 1.4 6.1 6.5 0.1 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding Lyase_1 PF00206.15 EWM26857.1 - 1.4e-85 287.2 0.0 2.1e-85 286.6 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 EWM26857.1 - 3.1e-26 91.2 0.0 7.7e-26 89.9 0.0 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal CVNH PF08881.5 EWM26857.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 CVNH domain Lyase_1 PF00206.15 EWM26858.1 - 7.6e-86 288.1 0.0 1e-85 287.6 0.0 1.2 1 0 0 1 1 1 1 Lyase CVNH PF08881.5 EWM26858.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 CVNH domain DASH_Hsk3 PF08227.6 EWM26859.1 - 0.09 12.9 0.3 0.2 11.9 0.0 1.7 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like TPR_12 PF13424.1 EWM26860.1 - 4.9e-07 29.5 18.1 0.0077 16.1 1.7 4.9 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 EWM26860.1 - 0.022 14.6 14.7 0.13 12.2 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 EWM26860.1 - 6.3 6.7 10.1 0.43 10.4 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat UPF0047 PF01894.12 EWM26862.1 - 6.9e-37 125.8 0.0 1.4e-36 124.8 0.0 1.5 1 1 0 1 1 1 1 Uncharacterised protein family UPF0047 Rad60-SLD PF11976.3 EWM26863.1 - 6.6e-06 25.7 0.4 1.6e-05 24.4 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ERM PF00769.14 EWM26863.1 - 0.00069 19.2 23.4 0.0013 18.2 16.2 1.4 1 0 0 1 1 1 1 Ezrin/radixin/moesin family APG6 PF04111.7 EWM26863.1 - 0.044 12.8 20.7 0.071 12.1 14.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 GAS PF13851.1 EWM26863.1 - 0.092 11.9 19.1 0.19 10.8 13.2 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding PA26 PF04636.8 EWM26863.1 - 0.39 9.3 3.4 0.8 8.3 2.3 1.5 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Nup54 PF13874.1 EWM26863.1 - 0.76 9.4 14.0 2.1 8.0 9.4 2.0 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 FUSC PF04632.7 EWM26863.1 - 1.7 6.9 6.6 2.4 6.5 4.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Vicilin_N PF04702.7 EWM26863.1 - 2.2 7.9 9.6 4.8 6.7 6.7 1.6 1 0 0 1 1 1 0 Vicilin N terminal region DUF4164 PF13747.1 EWM26863.1 - 3.3 7.8 23.3 0.054 13.6 6.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) IncA PF04156.9 EWM26863.1 - 3.8 7.0 25.5 4.1 6.9 16.5 1.7 1 1 1 2 2 2 0 IncA protein AAA_13 PF13166.1 EWM26863.1 - 6 5.1 13.8 2.4 6.5 7.0 1.7 1 1 1 2 2 2 0 AAA domain HALZ PF02183.13 EWM26863.1 - 7.5 6.3 13.6 0.72 9.6 3.3 2.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper V_ATPase_I PF01496.14 EWM26863.1 - 9.2 3.9 11.7 13 3.4 8.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PAP_fibrillin PF04755.7 EWM26864.1 - 3.3e-30 105.2 1.1 1.1e-24 87.2 0.0 2.0 1 1 1 2 2 2 2 PAP_fibrillin Saccharop_dh PF03435.13 EWM26865.1 - 3.1e-16 59.3 0.0 1.7e-15 56.9 0.0 1.9 1 1 0 2 2 2 1 Saccharopine dehydrogenase CENP-R PF06729.7 EWM26865.1 - 0.0027 17.3 0.0 0.0045 16.6 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component, CENP-R NmrA PF05368.8 EWM26865.1 - 0.061 12.5 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.1 EWM26865.1 - 0.063 13.2 0.1 0.43 10.5 0.0 2.2 1 1 1 2 2 2 0 NADH(P)-binding DUF849 PF05853.7 EWM26865.1 - 0.44 9.3 1.8 1.6 7.5 0.7 2.0 1 1 1 2 2 2 0 Prokaryotic protein of unknown function (DUF849) Pyr_redox_2 PF07992.9 EWM26866.1 - 0.001 18.9 0.2 0.0026 17.6 0.1 1.6 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF4448 PF14610.1 EWM26867.1 - 0.0004 19.9 0.1 0.00086 18.8 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) SKG6 PF08693.5 EWM26867.1 - 0.036 13.3 0.4 0.089 12.1 0.2 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CbtB PF09489.5 EWM26867.1 - 0.11 12.3 0.1 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) Lamp PF01299.12 EWM26867.1 - 0.92 8.5 0.0 0.92 8.5 0.0 2.3 3 0 0 3 3 3 0 Lysosome-associated membrane glycoprotein (Lamp) PPR_2 PF13041.1 EWM26868.1 - 1.5e-15 56.8 3.3 0.00073 19.4 0.0 7.8 6 2 2 9 9 9 3 PPR repeat family PPR_3 PF13812.1 EWM26868.1 - 4.8e-13 48.2 17.5 0.37 11.1 0.0 8.9 8 1 1 9 9 9 5 Pentatricopeptide repeat domain PPR PF01535.15 EWM26868.1 - 7.6e-08 31.8 17.7 0.24 11.4 0.0 9.5 10 0 0 10 10 10 3 PPR repeat ECSIT PF06239.6 EWM26868.1 - 0.0019 17.1 0.1 0.0067 15.3 0.0 1.9 2 0 0 2 2 2 1 Evolutionarily conserved signalling intermediate in Toll pathway Fer4_20 PF14691.1 EWM26869.1 - 0.015 14.9 0.2 0.029 14.0 0.1 1.4 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster GATase_2 PF00310.16 EWM26870.1 - 1e-19 70.4 0.1 1.2e-19 70.2 0.1 1.0 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 EWM26871.1 - 0.038 13.2 0.0 0.041 13.1 0.0 1.0 1 0 0 1 1 1 0 Glutamate synthase central domain GXGXG PF01493.14 EWM26873.1 - 3.1e-13 49.1 0.0 4.5e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 GXGXG motif Myosin_head PF00063.16 EWM26874.1 - 1.8e-40 138.7 0.0 2.2e-40 138.3 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) COPI_assoc PF08507.5 EWM26875.1 - 8.2e-10 38.5 4.9 1.1e-09 38.1 3.4 1.1 1 0 0 1 1 1 1 COPI associated protein DUF2428 PF10350.4 EWM26875.1 - 0.081 11.9 0.1 0.14 11.1 0.1 1.3 1 1 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) Cg6151-P PF10233.4 EWM26875.1 - 0.16 11.9 5.0 0.27 11.2 3.5 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein CG6151-P 7TMR-DISM_7TM PF07695.6 EWM26875.1 - 0.34 10.5 11.4 2.8 7.5 5.2 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling Cytochrom_B_N PF00033.14 EWM26875.1 - 0.89 8.8 8.4 3.2 7.0 5.8 1.9 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB YtpI PF14007.1 EWM26875.1 - 2.1 8.3 9.5 4.2 7.3 5.9 2.0 1 1 0 1 1 1 0 YtpI-like protein Neurensin PF14927.1 EWM26875.1 - 2.5 7.4 7.5 3.1 7.1 0.8 2.6 2 1 0 2 2 2 0 Neurensin CAF-1_p150 PF11600.3 EWM26876.1 - 0.032 13.5 0.6 0.032 13.5 0.4 1.4 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal FoP_duplication PF13865.1 EWM26878.1 - 7e-15 55.2 8.5 7e-15 55.2 5.9 3.9 2 1 3 5 5 5 1 C-terminal duplication domain of Friend of PRMT1 Nucleoporin_N PF08801.6 EWM26879.1 - 3.6e-07 29.2 0.0 4.6e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like HSP70 PF00012.15 EWM26880.1 - 8.5e-24 83.4 0.0 2.8e-23 81.6 0.0 1.7 2 0 0 2 2 2 1 Hsp70 protein BcrAD_BadFG PF01869.15 EWM26880.1 - 0.00051 19.4 0.0 0.00065 19.0 0.0 1.2 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family MreB_Mbl PF06723.8 EWM26880.1 - 0.0069 15.0 0.0 0.009 14.6 0.0 1.1 1 0 0 1 1 1 1 MreB/Mbl protein TLC PF03219.9 EWM26888.1 - 1.3e-09 37.1 1.1 1.4e-09 37.0 0.8 1.1 1 0 0 1 1 1 1 TLC ATP/ADP transporter ATP-synt_8 PF00895.15 EWM26888.1 - 0.088 13.0 0.4 0.2 11.8 0.2 1.6 1 0 0 1 1 1 0 ATP synthase protein 8 DUF1656 PF07869.7 EWM26888.1 - 9.6 6.0 10.1 1.2 8.9 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1656) Glyco_trans_2_3 PF13632.1 EWM26888.1 - 9.7 5.8 7.7 7.4 6.2 2.3 2.0 2 0 0 2 2 2 0 Glycosyl transferase family group 2 UPF0016 PF01169.14 EWM26889.1 - 1.2e-09 38.1 0.3 2.3e-09 37.2 0.2 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0016 PI3_PI4_kinase PF00454.22 EWM26890.1 - 3.1e-51 174.1 0.1 4.1e-51 173.7 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EWM26890.1 - 2e-18 65.5 0.0 4.8e-18 64.2 0.0 1.7 1 0 0 1 1 1 1 FATC domain APH PF01636.18 EWM26890.1 - 0.0061 16.3 0.4 0.026 14.2 0.3 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Cellulase PF00150.13 EWM26893.1 - 3.5e-34 118.2 0.1 4.3e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PP2C PF00481.16 EWM26894.1 - 2e-35 122.4 0.0 1.3e-16 60.7 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EWM26894.1 - 0.00035 20.0 0.1 0.003 17.0 0.0 2.2 2 0 0 2 2 2 1 Protein phosphatase 2C Flavodoxin_2 PF02525.12 EWM26895.1 - 6e-30 104.2 0.0 6.5e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 EWM26895.1 - 2.8e-11 43.1 0.0 4.4e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.2 EWM26895.1 - 0.0016 17.8 0.0 0.0026 17.1 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin Mito_carr PF00153.22 EWM26896.1 - 2.3e-27 94.5 0.1 3.7e-15 55.4 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein Cupin_8 PF13621.1 EWM26897.1 - 3.7e-16 59.3 0.0 4.1e-15 55.9 0.0 2.4 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EWM26897.1 - 7.2e-14 51.9 0.2 4.8e-07 30.0 0.1 2.8 2 0 0 2 2 2 2 JmjC domain, hydroxylase Cupin_4 PF08007.7 EWM26897.1 - 0.053 12.7 0.0 0.14 11.4 0.0 1.5 1 1 0 1 1 1 0 Cupin superfamily protein Cupin_2 PF07883.6 EWM26897.1 - 0.084 12.3 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 Cupin domain RbsD_FucU PF05025.8 EWM26898.1 - 9.2e-39 132.9 0.0 1e-38 132.8 0.0 1.0 1 0 0 1 1 1 1 RbsD / FucU transport protein family YonK PF09642.5 EWM26898.1 - 0.037 13.7 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 YonK protein YTH PF04146.10 EWM26899.1 - 2.1e-40 137.5 0.0 3e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 YT521-B-like domain Daxx PF03344.10 EWM26899.1 - 0.67 8.3 9.2 0.93 7.8 6.4 1.1 1 0 0 1 1 1 0 Daxx Family Claudin_2 PF13903.1 EWM26901.1 - 0.13 11.9 2.2 0.2 11.3 1.5 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NIF PF03031.13 EWM26902.1 - 1.2e-21 76.9 0.0 1.9e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.18 EWM26902.1 - 0.14 11.6 0.0 0.36 10.2 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin family PCMT PF01135.14 EWM26905.1 - 4.7e-66 222.3 0.0 5.7e-66 222.0 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EWM26905.1 - 1.5e-12 48.0 0.0 2.7e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM26905.1 - 4.8e-12 45.7 0.0 9e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 EWM26905.1 - 5.1e-08 32.2 0.0 1.2e-07 31.0 0.0 1.5 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_23 PF13489.1 EWM26905.1 - 5.4e-08 32.7 0.0 8.8e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM26905.1 - 8.5e-08 32.5 0.0 2.7e-07 30.9 0.0 2.0 2 1 0 2 2 1 1 Methyltransferase domain PrmA PF06325.8 EWM26905.1 - 1.5e-07 30.8 0.0 2.2e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EWM26905.1 - 7.4e-07 29.2 0.0 1.3e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EWM26905.1 - 1.1e-06 28.0 0.0 1.6e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EWM26905.1 - 3.6e-06 27.2 0.0 9.3e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain GCD14 PF08704.5 EWM26905.1 - 4.4e-06 26.3 0.0 5.6e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit MTS PF05175.9 EWM26905.1 - 5e-06 25.9 0.0 7.5e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 EWM26905.1 - 7.5e-06 25.6 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EWM26905.1 - 2e-05 23.8 0.0 2.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EWM26905.1 - 0.00015 22.1 0.0 0.00029 21.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EWM26905.1 - 0.00015 20.8 0.0 0.00022 20.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 EWM26905.1 - 0.0024 17.8 0.0 0.0043 17.0 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_9 PF08003.6 EWM26905.1 - 0.004 15.8 0.0 0.0059 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) RrnaAD PF00398.15 EWM26905.1 - 0.0075 15.3 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MetW PF07021.7 EWM26905.1 - 0.017 14.5 0.1 0.043 13.1 0.0 1.7 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW PCMT PF01135.14 EWM26906.1 - 1.9e-39 135.3 0.0 2.5e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EWM26906.1 - 3.7e-12 46.0 0.0 6e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM26906.1 - 1.3e-10 41.8 0.0 2.4e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM26906.1 - 1e-07 32.3 0.0 3e-07 30.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EWM26906.1 - 1.3e-07 31.0 0.0 2.2e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EWM26906.1 - 9.1e-07 28.9 0.0 1.8e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM26906.1 - 2e-06 27.5 0.0 3.3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EWM26906.1 - 2.6e-06 26.7 0.0 4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EWM26906.1 - 4.2e-06 26.2 0.0 6.1e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_3 PF01596.12 EWM26906.1 - 5.7e-06 25.5 0.0 1.4e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_32 PF13679.1 EWM26906.1 - 5.8e-06 26.0 0.0 8.6e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM26906.1 - 6.5e-06 26.4 0.0 2.1e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EWM26906.1 - 1.8e-05 23.9 0.0 2.5e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase GCD14 PF08704.5 EWM26906.1 - 2.4e-05 23.9 0.0 3.4e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_4 PF02390.12 EWM26906.1 - 0.00011 21.2 0.0 0.00016 20.8 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.7 EWM26906.1 - 0.00062 20.2 0.0 0.0013 19.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EWM26906.1 - 0.0017 18.3 0.0 0.003 17.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_9 PF08003.6 EWM26906.1 - 0.0031 16.2 0.0 0.0042 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) RrnaAD PF00398.15 EWM26906.1 - 0.0049 15.9 0.0 0.0071 15.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase tRNA_U5-meth_tr PF05958.6 EWM26906.1 - 0.0062 15.2 0.0 0.0072 15.0 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase MetW PF07021.7 EWM26906.1 - 0.0096 15.3 0.1 0.027 13.8 0.0 1.8 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Ribosomal_S10 PF00338.17 EWM26907.1 - 1.7e-28 98.2 0.8 2.1e-28 98.0 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e LRR_4 PF12799.2 EWM26910.1 - 0.0015 18.0 2.3 2 8.0 0.0 5.1 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EWM26910.1 - 0.0058 16.5 4.8 9.7 6.6 0.0 5.7 6 0 0 6 6 6 1 Leucine Rich repeat F-box PF00646.28 EWM26910.1 - 0.014 15.0 0.4 0.062 12.9 0.3 2.2 1 0 0 1 1 1 0 F-box domain LRR_1 PF00560.28 EWM26910.1 - 0.02 14.8 0.3 1.5e+02 3.0 0.0 5.6 4 0 0 4 4 4 0 Leucine Rich Repeat Arrestin_N PF00339.24 EWM26911.1 - 1e-11 44.8 0.0 2.3e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EWM26911.1 - 4.2e-08 33.3 0.0 0.011 15.8 0.0 3.1 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain ChlI PF13541.1 EWM26911.1 - 0.076 12.5 0.0 9.2 5.8 0.0 2.4 2 0 0 2 2 2 0 Subunit ChlI of Mg-chelatase Transglut_C PF00927.17 EWM26911.1 - 0.13 12.3 0.0 0.4 10.7 0.0 1.8 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain DNA_pol3_alpha PF07733.7 EWM26911.1 - 0.13 10.6 0.0 0.22 9.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha subunit Tropomyosin_1 PF12718.2 EWM26912.1 - 0.23 11.2 9.0 0.057 13.2 3.5 1.9 1 1 0 2 2 2 0 Tropomyosin like Methyltransf_31 PF13847.1 EWM26913.1 - 1.8e-13 50.3 0.0 3.1e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM26913.1 - 2.8e-11 44.0 0.0 7.8e-11 42.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EWM26913.1 - 7.4e-11 41.9 0.0 2e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EWM26913.1 - 4.5e-10 39.1 0.0 9.8e-10 38.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EWM26913.1 - 2.8e-09 37.0 1.0 7.7e-09 35.5 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM26913.1 - 9.5e-08 32.3 0.0 3.1e-07 30.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM26913.1 - 3.4e-06 27.4 0.0 1.6e-05 25.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM26913.1 - 4.8e-05 23.7 0.0 0.00017 21.9 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain PCMT PF01135.14 EWM26913.1 - 0.0012 18.3 0.0 0.013 15.0 0.0 2.1 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GidB PF02527.10 EWM26913.1 - 0.0039 16.3 0.0 0.0079 15.3 0.0 1.4 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_4 PF02390.12 EWM26913.1 - 0.0077 15.3 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 EWM26913.1 - 0.012 14.7 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 EWM26913.1 - 0.021 14.5 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 EWM26913.1 - 0.12 11.4 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Cyclin_N PF00134.18 EWM26914.1 - 2.6e-28 98.1 0.0 6.3e-25 87.1 0.0 2.3 1 1 1 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 EWM26914.1 - 4.8e-21 74.8 0.5 1.3e-20 73.5 0.1 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain F-box-like PF12937.2 EWM26914.1 - 0.0053 16.4 0.1 0.015 14.9 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EWM26914.1 - 0.018 14.6 0.2 0.67 9.6 0.0 2.7 2 0 0 2 2 2 0 F-box domain MutS_III PF05192.13 EWM26915.1 - 0.17 11.6 7.1 0.43 10.3 4.1 2.2 2 1 0 2 2 2 0 MutS domain III EcKinase PF02958.15 EWM26915.1 - 0.32 10.0 3.3 0.58 9.2 2.3 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase MFS_1 PF07690.11 EWM26916.1 - 2.8e-52 177.6 29.3 2.8e-52 177.6 20.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EWM26916.1 - 5.7e-11 41.6 9.2 1.1e-10 40.7 6.2 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter BT1 PF03092.11 EWM26916.1 - 0.0063 15.2 2.5 0.014 14.1 0.0 2.1 1 1 0 2 2 2 1 BT1 family DUF1228 PF06779.9 EWM26916.1 - 0.014 15.3 5.9 0.079 12.9 0.7 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) EMP70 PF02990.11 EWM26916.1 - 5.7 5.2 6.3 0.61 8.4 0.6 1.8 2 0 0 2 2 2 0 Endomembrane protein 70 Pkinase PF00069.20 EWM26917.1 - 4.8e-28 98.0 0.0 1.4e-27 96.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM26917.1 - 1.8e-09 37.0 0.0 3e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EWM26917.1 - 0.00037 20.2 0.0 0.00082 19.1 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EWM26917.1 - 0.0039 16.5 0.0 0.0072 15.7 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.6 EWM26917.1 - 0.034 13.0 0.0 0.056 12.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.1 EWM26917.1 - 0.19 10.6 0.0 0.46 9.3 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Polyketide_cyc PF03364.15 EWM26918.1 - 1.5e-16 60.5 0.3 2.2e-16 60.0 0.2 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 EWM26918.1 - 9.2e-10 38.8 0.1 1.9e-09 37.8 0.1 1.6 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Coatomer_E PF04733.9 EWM26919.1 - 7.6e-36 123.7 0.1 8.5e-36 123.6 0.1 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_11 PF13414.1 EWM26919.1 - 7.6e-10 38.2 2.7 4.4e-05 23.0 0.1 1.5 1 1 1 2 2 2 2 TPR repeat TPR_16 PF13432.1 EWM26919.1 - 3.3e-07 30.7 0.8 1.7e-05 25.3 0.4 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EWM26919.1 - 6.7e-07 29.5 1.9 2.1e-05 24.7 0.5 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EWM26919.1 - 1.3e-05 24.7 1.0 4.5e-05 23.0 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EWM26919.1 - 7.7e-05 22.5 0.4 0.00017 21.4 0.2 1.6 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EWM26919.1 - 8.5e-05 21.9 0.0 0.00032 20.1 0.1 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EWM26919.1 - 0.00014 22.1 0.0 0.21 12.1 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EWM26919.1 - 0.00036 20.9 1.1 0.027 15.0 0.1 3.4 1 1 3 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EWM26919.1 - 0.0021 17.8 0.1 0.0044 16.8 0.1 1.5 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.1 EWM26919.1 - 0.008 15.8 0.1 0.024 14.4 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 EWM26919.1 - 0.019 15.1 0.4 0.39 11.0 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 EWM26919.1 - 0.054 13.6 0.1 0.081 13.0 0.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Type_III_YscG PF09477.5 EWM26919.1 - 0.097 12.7 0.1 2.2 8.3 0.0 2.3 1 1 1 2 2 2 0 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_10 PF13374.1 EWM26919.1 - 9.9 6.2 8.2 0.46 10.5 0.2 2.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Ion_trans PF00520.26 EWM26920.1 - 9.4e-19 67.4 42.0 1.8e-09 37.1 12.2 2.7 2 0 0 2 2 2 2 Ion transport protein CytochromB561_N PF09786.4 EWM26920.1 - 0.064 11.7 0.1 0.064 11.7 0.1 2.0 2 0 0 2 2 2 0 Cytochrome B561, N terminal DUF3493 PF11998.3 EWM26921.1 - 2.3e-16 59.4 0.1 4.1e-16 58.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3493) CcoS PF03597.10 EWM26921.1 - 0.15 11.5 3.2 0.68 9.4 0.1 2.9 3 0 0 3 3 3 0 Cytochrome oxidase maturation protein cbb3-type RNA_pol_Rpc34 PF05158.7 EWM26922.1 - 3.8e-53 180.8 0.7 5e-53 180.4 0.5 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit WAPL PF07814.8 EWM26922.1 - 0.0035 16.1 0.5 0.005 15.6 0.3 1.2 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin B-block_TFIIIC PF04182.7 EWM26922.1 - 0.0037 17.0 0.6 0.0064 16.3 0.4 1.4 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC TrmB PF01978.14 EWM26922.1 - 0.068 12.8 0.2 0.89 9.3 0.2 2.4 2 1 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB TFIIE_alpha PF02002.12 EWM26922.1 - 0.12 11.9 0.4 0.32 10.5 0.1 1.8 2 0 0 2 2 2 0 TFIIE alpha subunit RNA_pol_Rpc34 PF05158.7 EWM26923.1 - 2.3e-59 201.2 0.8 9.3e-57 192.6 0.5 2.0 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.7 EWM26923.1 - 0.0031 17.3 0.6 0.0057 16.4 0.4 1.4 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC WAPL PF07814.8 EWM26923.1 - 0.0034 16.1 0.5 0.0043 15.8 0.3 1.1 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin TrmB PF01978.14 EWM26923.1 - 0.053 13.2 0.2 0.79 9.4 0.2 2.5 2 1 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB TFIIE_alpha PF02002.12 EWM26923.1 - 0.092 12.2 0.4 0.28 10.7 0.1 1.9 2 0 0 2 2 2 0 TFIIE alpha subunit RNA_pol_Rpc34 PF05158.7 EWM26924.1 - 3.8e-53 180.8 0.7 5e-53 180.4 0.5 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit WAPL PF07814.8 EWM26924.1 - 0.0035 16.1 0.5 0.005 15.6 0.3 1.2 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin B-block_TFIIIC PF04182.7 EWM26924.1 - 0.0037 17.0 0.6 0.0064 16.3 0.4 1.4 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC TrmB PF01978.14 EWM26924.1 - 0.068 12.8 0.2 0.89 9.3 0.2 2.4 2 1 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB TFIIE_alpha PF02002.12 EWM26924.1 - 0.12 11.9 0.4 0.32 10.5 0.1 1.8 2 0 0 2 2 2 0 TFIIE alpha subunit IBR PF01485.16 EWM26925.1 - 9.1e-15 54.2 42.9 1.1e-09 37.9 5.7 4.3 3 1 1 4 4 4 3 IBR domain Myb_DNA-binding PF00249.26 EWM26926.1 - 3.8e-11 42.8 0.7 5.4e-10 39.1 0.1 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain ZZ PF00569.12 EWM26926.1 - 5e-07 29.1 6.2 6.8e-07 28.7 2.7 2.1 2 0 0 2 2 2 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.1 EWM26926.1 - 3.9e-05 23.6 0.1 0.00015 21.7 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Coatomer_E PF04733.9 EWM26927.1 - 7.5e-13 48.3 0.0 9e-13 48.0 0.0 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit SWIRM PF04433.12 EWM26928.1 - 4.7e-07 29.8 0.0 2.7e-06 27.4 0.0 2.0 1 1 0 1 1 1 1 SWIRM domain WD40 PF00400.27 EWM26929.1 - 4.7e-15 54.7 11.1 3.8e-06 26.5 0.6 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat DUF3934 PF13070.1 EWM26929.1 - 0.45 10.7 2.8 1 9.6 2.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3934) RIO1 PF01163.17 EWM26930.1 - 2.4e-53 180.3 0.0 9.1e-27 93.6 0.0 2.2 2 0 0 2 2 2 2 RIO1 family APH PF01636.18 EWM26930.1 - 4.2e-08 33.2 0.4 2.5e-05 24.1 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EWM26930.1 - 0.01 14.9 0.8 0.1 11.6 0.2 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family UIM PF02809.15 EWM26930.1 - 0.065 12.8 0.3 0.065 12.8 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin interaction motif SRPRB PF09439.5 EWM26931.1 - 1.8e-36 125.0 0.0 2.6e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 EWM26931.1 - 8.4e-15 54.4 0.0 1.2e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EWM26931.1 - 6.6e-06 26.0 0.0 1.2e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EWM26931.1 - 1.5e-05 25.4 0.0 2.9e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EWM26931.1 - 0.00052 19.4 0.0 0.12 11.8 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EWM26931.1 - 0.00057 19.0 0.0 0.0007 18.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 EWM26931.1 - 0.004 17.1 0.2 0.06 13.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EWM26931.1 - 0.0067 16.5 0.0 0.021 14.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain Ras PF00071.17 EWM26931.1 - 0.016 14.5 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Ras family cobW PF02492.14 EWM26931.1 - 0.028 13.8 0.1 0.81 9.1 0.0 2.2 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 EWM26931.1 - 0.039 13.4 0.0 1 8.8 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein G-alpha PF00503.15 EWM26931.1 - 0.079 11.6 0.0 0.97 8.0 0.0 1.9 1 1 1 2 2 2 0 G-protein alpha subunit Zeta_toxin PF06414.7 EWM26931.1 - 0.086 11.9 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 EWM26931.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain His_Phos_2 PF00328.17 EWM26932.1 - 0.0015 17.9 0.0 0.0019 17.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF740 PF05340.7 EWM26932.1 - 0.96 7.7 4.4 1.2 7.3 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Fascin PF06268.8 EWM26935.1 - 7.3e-05 22.8 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 Fascin domain FRG1 PF06229.7 EWM26935.1 - 0.00034 20.1 0.0 0.00039 19.9 0.0 1.2 1 0 0 1 1 1 1 FRG1-like family FGF PF00167.13 EWM26935.1 - 0.005 16.6 0.2 0.14 11.9 0.0 1.7 1 1 1 2 2 2 2 Fibroblast growth factor Mis12 PF05859.7 EWM26940.1 - 9.5e-06 25.4 0.0 1.7e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Mis12 protein zf-CCCH PF00642.19 EWM26941.1 - 1.3e-05 24.7 0.8 2.4e-05 23.8 0.6 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EWM26941.1 - 1 9.4 3.9 0.28 11.2 0.6 1.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type DUF4231 PF14015.1 EWM26944.1 - 0.066 13.1 2.2 0.71 9.8 1.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) DUF3995 PF13160.1 EWM26944.1 - 0.13 12.2 2.1 0.72 9.9 1.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3995) SNARE_assoc PF09335.6 EWM26945.1 - 5.5e-08 33.0 4.2 9e-08 32.3 0.8 2.1 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF4231 PF14015.1 EWM26945.1 - 0.12 12.3 2.5 0.92 9.5 1.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) DUF1469 PF07332.6 EWM26945.1 - 7.3 6.3 6.6 1.2 8.8 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) DUF303 PF03629.13 EWM26948.1 - 0.00084 18.6 0.0 0.0011 18.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF303) DUF303 PF03629.13 EWM26950.1 - 2.6e-21 76.0 0.0 3.7e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF303) EamA PF00892.15 EWM26952.1 - 0.00079 19.4 2.1 0.00079 19.4 1.4 3.9 4 1 0 4 4 4 3 EamA-like transporter family Rab5ip PF07019.7 EWM26953.1 - 2.6e-12 46.6 5.2 3.6e-12 46.2 3.3 1.4 2 0 0 2 2 2 1 Rab5-interacting protein (Rab5ip) BING4CT PF08149.6 EWM26955.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 BING4CT (NUC141) domain Acid_PPase PF12689.2 EWM26956.1 - 1.2e-18 67.3 0.1 1.5e-13 50.7 0.0 2.4 1 1 1 2 2 2 2 Acid Phosphatase HAD_2 PF13419.1 EWM26956.1 - 0.0008 19.6 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase NIF PF03031.13 EWM26956.1 - 0.023 14.3 0.0 5.5 6.6 0.0 3.0 3 0 0 3 3 3 0 NLI interacting factor-like phosphatase DUF2608 PF11019.3 EWM26956.1 - 0.043 12.8 0.0 0.23 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) ABC1 PF03109.11 EWM26957.1 - 0.58 10.1 3.9 0.33 10.9 1.0 1.8 1 1 1 2 2 2 0 ABC1 family DUF1283 PF06932.6 EWM26957.1 - 2.6 8.1 6.3 5.2 7.1 4.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1283) DUF2252 PF10009.4 EWM26957.1 - 4.1 6.1 11.6 5 5.9 8.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) SLY PF12485.3 EWM26957.1 - 5.5 7.2 10.5 6 7.0 0.7 2.1 1 1 1 2 2 2 0 Lymphocyte signaling adaptor protein WD40 PF00400.27 EWM26958.1 - 1.8e-17 62.4 2.6 1.2e-14 53.5 0.1 3.5 4 0 0 4 4 4 2 WD domain, G-beta repeat WD40 PF00400.27 EWM26959.1 - 2.5e-17 62.0 0.0 4.7e-06 26.2 0.0 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat TUG-UBL1 PF11470.3 EWM26959.1 - 0.02 14.7 0.0 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 GLUT4 regulating protein TUG DUF1682 PF07946.9 EWM26962.1 - 1.9e-26 92.6 0.0 2.8e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF3377 PF11857.3 EWM26963.1 - 0.14 11.8 0.1 0.37 10.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF1682 PF07946.9 EWM26964.1 - 2.5e-14 52.8 5.9 2.9e-14 52.6 4.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) RNA_polI_A34 PF08208.6 EWM26964.1 - 0.0024 17.5 6.8 0.0027 17.3 4.7 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 DUF3653 PF12375.3 EWM26964.1 - 0.29 11.3 4.9 0.67 10.2 3.4 1.6 1 1 0 1 1 1 0 Phage protein Dala_Dala_lig_N PF01820.16 EWM26964.1 - 0.48 10.7 1.8 0.62 10.3 1.2 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus RR_TM4-6 PF06459.7 EWM26964.1 - 6.8 6.5 9.0 8 6.2 6.3 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Rhodanese PF00581.15 EWM26965.1 - 0.019 15.3 0.0 0.6 10.4 0.0 2.3 2 0 0 2 2 2 0 Rhodanese-like domain zf-MYND PF01753.13 EWM26966.1 - 3.5e-08 33.1 8.4 3.5e-08 33.1 5.8 2.4 2 0 0 2 2 2 1 MYND finger TspO_MBR PF03073.10 EWM26967.1 - 1.3e-05 24.7 0.2 1.3e-05 24.7 0.1 1.9 2 0 0 2 2 2 1 TspO/MBR family DAP3 PF10236.4 EWM26968.1 - 7.8e-28 97.2 0.0 1.2e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 EWM26968.1 - 0.00071 19.6 0.0 0.0015 18.5 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EWM26968.1 - 0.0037 16.9 0.0 0.013 15.2 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain T2SE PF00437.15 EWM26968.1 - 0.024 13.5 0.0 0.036 12.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 EWM26968.1 - 0.027 14.1 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase RabGAP-TBC PF00566.13 EWM26970.1 - 2.3e-28 99.1 0.0 2.7e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Spore_coat_CotO PF14153.1 EWM26971.1 - 0.065 12.6 4.8 0.075 12.4 3.3 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Radial_spoke PF04712.7 EWM26971.1 - 0.96 8.1 16.1 1.2 7.8 11.1 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein BSP_II PF05432.6 EWM26971.1 - 3.2 6.9 21.7 4.8 6.3 15.1 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) FAM176 PF14851.1 EWM26971.1 - 6.7 6.3 8.9 9.5 5.8 6.2 1.2 1 0 0 1 1 1 0 FAM176 family DUF2457 PF10446.4 EWM26971.1 - 7.2 5.2 15.1 9.1 4.8 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Daxx PF03344.10 EWM26971.1 - 7.5 4.9 19.3 8.5 4.7 13.4 1.0 1 0 0 1 1 1 0 Daxx Family Cupin_4 PF08007.7 EWM26972.1 - 4.4e-13 49.1 0.2 0.00017 20.9 0.0 3.2 3 0 0 3 3 3 3 Cupin superfamily protein Cupin_8 PF13621.1 EWM26972.1 - 1.7e-12 47.4 0.0 2.6e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.6 EWM26972.1 - 0.02 14.4 0.0 0.45 10.0 0.0 2.6 2 0 0 2 2 2 0 Cupin domain JmjC PF02373.17 EWM26972.1 - 0.1 12.8 0.0 0.53 10.5 0.0 2.0 2 0 0 2 2 2 0 JmjC domain, hydroxylase CorA PF01544.13 EWM26973.1 - 2e-30 105.8 0.8 5e-28 97.9 0.1 2.1 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein EF-hand_6 PF13405.1 EWM26973.1 - 0.00094 18.8 0.0 0.78 9.7 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EWM26973.1 - 0.006 15.8 0.0 0.15 11.4 0.0 2.5 2 0 0 2 2 2 1 EF hand KxDL PF10241.4 EWM26973.1 - 0.098 12.5 0.2 3 7.7 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein ET PF01684.11 EWM26974.1 - 0.071 13.1 2.5 0.15 12.0 1.7 1.5 1 0 0 1 1 1 0 ET module Med15 PF09606.5 EWM26974.1 - 1.9 6.6 4.7 2.9 5.9 3.3 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Glyoxalase_2 PF12681.2 EWM26975.1 - 4.7e-14 52.9 0.0 6.1e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EWM26975.1 - 5.4e-14 52.2 0.0 7.1e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EWM26975.1 - 1.7e-11 44.0 0.0 2.3e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EWM26975.1 - 0.061 13.2 0.0 0.099 12.5 0.0 1.3 1 1 0 1 1 1 0 Glyoxalase-like domain Hist_deacetyl PF00850.14 EWM26976.1 - 6.3e-62 209.6 0.0 7.7e-62 209.3 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Aminotran_1_2 PF00155.16 EWM26977.1 - 4.4e-40 137.7 0.0 5.4e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EWM26977.1 - 0.0017 17.5 0.0 0.0065 15.6 0.0 1.7 2 0 0 2 2 2 1 Beta-eliminating lyase DUF2888 PF11135.3 EWM26977.1 - 0.13 11.9 0.0 1.6 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2888) PIG-S PF10510.4 EWM26978.1 - 1e-05 24.4 0.0 1.2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein DSHCT PF08148.7 EWM26979.1 - 4.4e-54 182.4 0.0 1.1e-53 181.1 0.0 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.1 EWM26979.1 - 4.4e-09 35.9 0.0 0.00019 20.6 0.0 2.6 3 0 0 3 3 3 2 rRNA-processing arch domain Helicase_C PF00271.26 EWM26979.1 - 8.3e-07 28.7 0.0 2.6e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Phage_holin_5 PF06946.6 EWM26980.1 - 0.11 12.7 1.1 0.31 11.2 0.1 2.1 2 0 0 2 2 2 0 Phage holin PCI PF01399.22 EWM26981.1 - 1.4e-14 54.2 0.4 2.4e-13 50.3 0.1 2.9 3 0 0 3 3 3 1 PCI domain RPN7 PF10602.4 EWM26981.1 - 0.023 14.0 0.1 0.051 12.9 0.1 1.6 1 0 0 1 1 1 0 26S proteasome subunit RPN7 DDRGK PF09756.4 EWM26981.1 - 0.15 11.4 0.1 0.3 10.4 0.1 1.4 1 0 0 1 1 1 0 DDRGK domain TPR_16 PF13432.1 EWM26981.1 - 1.2 9.9 18.2 1.9 9.2 2.8 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EWM26981.1 - 1.4 8.8 0.0 1.4 8.8 0.0 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 EWM26981.1 - 2.4 8.2 0.0 2.4 8.2 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 EWM26981.1 - 6.8 6.7 6.8 4.2 7.4 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DoxX_3 PF13781.1 EWM26983.1 - 0.024 15.0 0.3 0.063 13.6 0.2 1.7 1 0 0 1 1 1 0 DoxX-like family GATA PF00320.22 EWM26983.1 - 0.053 12.8 0.4 0.087 12.1 0.3 1.3 1 0 0 1 1 1 0 GATA zinc finger Cyto_ox_2 PF02322.10 EWM26983.1 - 0.12 11.5 6.7 0.14 11.3 4.6 1.2 1 0 0 1 1 1 0 Cytochrome oxidase subunit II Virul_fac_BrkB PF03631.10 EWM26983.1 - 3.3 7.0 10.2 7.5 5.8 4.9 2.4 1 1 0 1 1 1 0 Virulence factor BrkB EBP PF05241.7 EWM26984.1 - 5e-46 156.1 0.8 5e-46 156.1 0.5 2.0 2 0 0 2 2 2 2 Emopamil binding protein MPC PF03650.8 EWM26988.1 - 2.9e-35 120.8 0.1 2.9e-35 120.7 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) CorA PF01544.13 EWM26989.1 - 1.1e-20 73.9 0.1 7.5e-17 61.2 0.0 2.3 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Polyketide_cyc PF03364.15 EWM26990.1 - 9.5e-15 54.7 0.0 1.2e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport FAM104 PF15434.1 EWM26991.1 - 0.033 14.3 0.1 0.042 14.0 0.0 1.2 1 0 0 1 1 1 0 Family 104 DEAD PF00270.24 EWM26992.1 - 5e-13 48.8 0.0 6.8e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.11 EWM26992.1 - 0.052 12.7 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.10 EWM26992.1 - 0.064 13.0 0.0 0.074 12.8 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit LON PF02190.11 EWM26994.1 - 1.5e-14 54.1 0.0 1.8e-14 53.9 0.0 1.0 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain Mannitol_dh_C PF08125.8 EWM26995.1 - 6.5e-66 221.9 0.0 1e-65 221.3 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 EWM26995.1 - 3.3e-34 117.9 0.0 1.3e-25 90.1 0.0 2.6 2 0 0 2 2 2 2 Mannitol dehydrogenase Rossmann domain SNF2_N PF00176.18 EWM26996.1 - 5.1e-72 242.2 0.0 1.1e-71 241.0 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4 PF00097.20 EWM26996.1 - 4.6e-07 29.4 9.5 4.6e-07 29.4 6.6 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EWM26996.1 - 8.4e-07 28.5 6.4 8.4e-07 28.5 4.5 3.6 3 0 0 3 3 3 1 PHD-finger zf-RING_2 PF13639.1 EWM26996.1 - 8.3e-06 25.5 8.8 8.3e-06 25.5 6.1 3.7 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.1 EWM26996.1 - 1.3e-05 25.1 9.5 1.3e-05 25.1 6.6 3.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EWM26996.1 - 0.00011 21.8 8.8 0.00011 21.8 6.1 3.4 3 0 0 3 3 3 1 zinc-RING finger domain Helicase_C PF00271.26 EWM26996.1 - 0.00055 19.7 1.4 0.001 18.8 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.1 EWM26996.1 - 0.006 16.2 5.7 0.016 14.9 3.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger 14-3-3 PF00244.15 EWM26996.1 - 0.017 14.1 11.1 0.04 13.0 0.2 2.6 2 0 0 2 2 2 0 14-3-3 protein zf-RING_4 PF14570.1 EWM26996.1 - 3 7.5 17.3 0.014 14.9 5.2 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain LYTB PF02401.13 EWM26997.1 - 3.5e-81 272.2 0.1 4.6e-81 271.8 0.0 1.1 1 0 0 1 1 1 1 LytB protein DUF1459 PF07312.6 EWM26997.1 - 0.073 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1459) Glyco_tranf_2_3 PF13641.1 EWM26998.1 - 2.5e-31 109.2 0.0 3.7e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Cellulose_synt PF03552.9 EWM26998.1 - 2.4e-29 102.1 7.4 5.7e-19 67.9 1.5 3.2 1 1 2 3 3 3 3 Cellulose synthase Glyco_trans_2_3 PF13632.1 EWM26998.1 - 2.1e-18 66.7 3.0 2.1e-18 66.7 2.1 2.2 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 EWM26998.1 - 1.6e-10 40.5 0.0 7.2e-10 38.4 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EWM26998.1 - 1.6e-09 37.7 0.0 5.3e-09 35.9 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 2 Chitin_synth_2 PF03142.10 EWM26998.1 - 5.4e-05 21.7 0.0 0.1 10.9 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase PDR_assoc PF08370.6 EWM26998.1 - 0.27 10.7 3.1 2.7 7.5 0.6 2.6 2 0 0 2 2 2 0 Plant PDR ABC transporter associated ABC_membrane PF00664.18 EWM26999.1 - 7.4e-40 137.0 4.8 8.8e-40 136.8 3.4 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_membrane_3 PF13748.1 EWM26999.1 - 0.0075 15.3 1.4 0.011 14.8 0.3 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_membrane PF00664.18 EWM27000.1 - 1.7e-39 135.9 4.8 2.2e-39 135.5 3.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EWM27000.1 - 1.2e-28 100.0 0.0 2.3e-28 99.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 EWM27000.1 - 0.00061 19.8 0.2 0.002 18.1 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EWM27000.1 - 0.0008 19.5 0.0 0.0047 17.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 EWM27000.1 - 0.00097 18.4 0.1 0.097 11.8 0.0 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 EWM27000.1 - 0.002 16.8 0.0 0.0032 16.1 0.0 1.2 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_25 PF13481.1 EWM27000.1 - 0.003 16.9 0.1 0.009 15.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EWM27000.1 - 0.0038 16.6 0.0 0.19 11.1 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_21 PF13304.1 EWM27000.1 - 0.0095 15.9 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EWM27000.1 - 0.011 16.5 0.0 0.022 15.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_membrane_3 PF13748.1 EWM27000.1 - 0.011 14.7 1.0 0.018 14.0 0.2 1.6 2 0 0 2 2 2 0 ABC transporter transmembrane region DUF258 PF03193.11 EWM27000.1 - 0.038 13.1 0.0 1.1 8.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Mg_chelatase PF01078.16 EWM27000.1 - 0.047 12.8 0.0 0.14 11.2 0.0 1.8 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EWM27000.1 - 0.072 13.3 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 EWM27000.1 - 0.1 12.1 0.0 0.4 10.1 0.0 2.0 2 1 0 2 2 2 0 DEAD/DEAH box helicase PRK PF00485.13 EWM27000.1 - 0.18 11.3 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Lon_C PF05362.8 EWM27001.1 - 1.3e-69 233.6 1.1 3.4e-69 232.2 0.1 2.0 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 EWM27001.1 - 1.1e-22 80.6 0.0 2.4e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 EWM27001.1 - 2.3e-08 33.5 0.0 3.3e-07 29.8 0.0 2.6 3 0 0 3 3 2 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.9 EWM27001.1 - 1e-05 25.5 0.0 3.6e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EWM27001.1 - 3.3e-05 23.6 0.0 5.7e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EWM27001.1 - 6.3e-05 23.7 0.0 0.00023 21.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 EWM27001.1 - 6.7e-05 21.7 0.0 0.00014 20.7 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.7 EWM27001.1 - 0.00038 19.5 0.0 0.001 18.1 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EWM27001.1 - 0.00042 20.4 2.0 0.033 14.3 0.1 3.3 3 1 0 3 3 2 1 AAA domain AAA_16 PF13191.1 EWM27001.1 - 0.00044 20.2 1.8 0.0012 18.9 0.1 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_18 PF13238.1 EWM27001.1 - 0.0055 16.9 0.4 0.02 15.1 0.0 2.2 2 1 1 3 3 1 1 AAA domain DUF258 PF03193.11 EWM27001.1 - 0.011 14.8 0.2 0.058 12.5 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 EWM27001.1 - 0.013 14.9 0.0 0.027 13.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_23 PF13476.1 EWM27001.1 - 0.013 15.8 3.6 0.83 9.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EWM27001.1 - 0.032 14.3 0.0 0.063 13.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 EWM27001.1 - 0.052 12.9 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EWM27001.1 - 0.076 12.8 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EWM27001.1 - 0.076 12.9 0.0 0.23 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain SKI PF01202.17 EWM27001.1 - 0.11 12.4 0.1 0.11 12.4 0.1 2.4 2 0 0 2 2 2 0 Shikimate kinase TIP49 PF06068.8 EWM27001.1 - 0.11 11.1 0.2 0.24 10.0 0.1 1.5 2 0 0 2 2 2 0 TIP49 C-terminus AAA_24 PF13479.1 EWM27001.1 - 0.13 11.8 0.1 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 EWM27001.1 - 0.13 12.0 2.0 9.3 6.0 0.5 2.4 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_3 PF07726.6 EWM27001.1 - 0.16 11.5 0.0 0.35 10.4 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FlxA PF14282.1 EWM27001.1 - 0.36 10.7 2.6 0.89 9.5 1.8 1.6 1 0 0 1 1 1 0 FlxA-like protein PALP PF00291.20 EWM27002.1 - 4.7e-56 190.2 0.9 4.7e-56 190.2 0.6 1.4 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.21 EWM27002.1 - 0.15 11.6 1.7 0.83 9.2 0.6 2.5 2 1 0 2 2 2 0 Zinc-binding dehydrogenase zf-GRF PF06839.7 EWM27003.1 - 1.4e-16 60.1 0.5 1.4e-16 60.1 0.4 2.7 3 0 0 3 3 3 1 GRF zinc finger NUDIX PF00293.23 EWM27004.1 - 1.6e-10 40.7 0.0 2.1e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain CPSase_L_D2 PF02786.12 EWM27005.1 - 6.6e-73 244.4 0.1 1.5e-72 243.3 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EWM27005.1 - 5.1e-41 139.2 0.2 2.8e-40 136.8 0.0 2.2 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EWM27005.1 - 1e-33 115.5 0.0 2.4e-33 114.3 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 EWM27005.1 - 4.8e-15 55.7 0.1 1.2e-14 54.4 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EWM27005.1 - 6e-15 54.6 0.3 1.6e-14 53.3 0.2 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EWM27005.1 - 4e-10 38.9 0.1 8.3e-10 37.9 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EWM27005.1 - 1e-09 38.0 0.1 2.5e-09 36.7 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EWM27005.1 - 1.9e-09 37.2 0.1 5.7e-09 35.6 0.0 1.8 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EWM27005.1 - 5.8e-05 23.0 0.2 0.00015 21.6 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.6 EWM27005.1 - 0.00014 21.4 0.0 0.00073 19.0 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain GARS_A PF01071.14 EWM27005.1 - 0.00047 19.7 0.1 0.00092 18.8 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Biotin_lipoyl_2 PF13533.1 EWM27005.1 - 0.0023 17.5 0.2 0.0074 15.9 0.1 1.9 1 1 1 2 2 2 1 Biotin-lipoyl like UPF0150 PF03681.10 EWM27005.1 - 0.0082 15.7 0.0 0.026 14.1 0.0 1.8 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0150) ATP-grasp_5 PF13549.1 EWM27005.1 - 0.018 14.2 0.0 0.04 13.1 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain DUF2950 PF11453.3 EWM27005.1 - 0.082 11.8 0.0 0.62 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2950) HlyD_2 PF12700.2 EWM27005.1 - 0.12 11.5 0.0 0.26 10.3 0.0 1.5 1 1 0 1 1 1 0 HlyD family secretion protein Phosphorylase PF00343.15 EWM27005.1 - 0.13 10.1 0.0 0.19 9.5 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate phosphorylase Peptidase_M16_C PF05193.16 EWM27006.1 - 1.3e-52 178.1 0.0 5.2e-28 97.9 0.0 3.3 2 1 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EWM27006.1 - 3.8e-15 55.9 0.1 1.1e-14 54.3 0.0 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) zf-MYND PF01753.13 EWM27007.1 - 5.9e-08 32.4 9.4 1.1e-07 31.6 6.5 1.5 1 0 0 1 1 1 1 MYND finger EamA PF00892.15 EWM27008.1 - 5.3e-09 36.1 28.1 0.00017 21.6 5.3 2.5 2 0 0 2 2 2 2 EamA-like transporter family Sugar_transport PF06800.7 EWM27008.1 - 0.0034 16.5 3.3 0.0035 16.4 1.4 1.7 1 1 0 1 1 1 1 Sugar transport protein CD52 PF15116.1 EWM27008.1 - 0.039 13.7 0.5 0.11 12.3 0.3 1.7 1 0 0 1 1 1 0 CAMPATH-1 antigen EMP70 PF02990.11 EWM27009.1 - 7.5e-196 651.6 9.7 9.4e-196 651.2 6.7 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 Fe-ADH PF00465.14 EWM27010.1 - 1.7e-68 230.9 0.0 2.3e-68 230.5 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EWM27010.1 - 1.1e-12 47.7 0.3 5.6e-06 25.8 0.1 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Ras PF00071.17 EWM27011.1 - 8.8e-39 132.4 0.0 1.3e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EWM27011.1 - 1.2e-18 67.7 0.0 2.6e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EWM27011.1 - 7.6e-12 44.8 0.0 1.2e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EWM27011.1 - 3e-05 23.2 0.2 0.00015 20.9 0.0 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EWM27011.1 - 0.00017 20.8 0.0 0.00027 20.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EWM27011.1 - 0.0011 18.9 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EWM27011.1 - 0.0013 18.1 0.0 0.0075 15.7 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 EWM27011.1 - 0.0044 15.7 0.0 0.074 11.7 0.0 2.1 2 0 0 2 2 2 1 G-protein alpha subunit Xan_ur_permease PF00860.15 EWM27012.1 - 1.2e-20 73.3 24.5 8.1e-14 50.9 5.9 2.3 2 0 0 2 2 2 2 Permease family BenE PF03594.8 EWM27012.1 - 3.2e-05 22.6 3.7 3.2e-05 22.6 2.6 3.0 3 1 0 3 3 3 1 Benzoate membrane transport protein Sulfate_transp PF00916.15 EWM27012.1 - 9.3e-05 21.5 2.5 9.3e-05 21.5 1.8 2.6 2 0 0 2 2 2 1 Sulfate transporter family ABC2_membrane PF01061.19 EWM27013.1 - 2.8e-25 88.7 23.9 2.8e-25 88.7 16.6 1.9 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.22 EWM27013.1 - 9.7e-24 84.2 0.0 1.5e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EWM27013.1 - 1.4e-08 35.0 0.0 1.2e-07 31.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EWM27013.1 - 8.2e-05 22.0 0.1 0.00023 20.6 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EWM27013.1 - 0.0017 17.5 0.0 0.003 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EWM27013.1 - 0.0023 17.3 0.0 0.0065 15.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EWM27013.1 - 0.0026 17.8 0.0 0.0093 16.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EWM27013.1 - 0.0042 17.4 0.1 0.0067 16.7 0.1 1.2 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 EWM27013.1 - 0.0057 15.9 0.0 0.012 14.8 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EWM27013.1 - 0.026 14.4 0.0 0.06 13.3 0.0 1.6 2 0 0 2 2 1 0 AAA ATPase domain AAA_10 PF12846.2 EWM27013.1 - 0.083 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain RNA_helicase PF00910.17 EWM27013.1 - 0.087 13.0 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Tubulin_2 PF13809.1 EWM27013.1 - 0.1 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Tubulin like AAA PF00004.24 EWM27013.1 - 0.12 12.5 0.0 1.3 9.1 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TMEM95 PF15203.1 EWM27013.1 - 0.13 11.6 0.0 1.9 7.8 0.0 2.1 2 0 0 2 2 2 0 TMEM95 family AAA_19 PF13245.1 EWM27013.1 - 0.13 11.9 0.1 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain DUF4191 PF13829.1 EWM27013.1 - 1.4 8.0 3.3 2.7 7.0 2.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) ABC2_membrane_3 PF12698.2 EWM27013.1 - 2.1 7.3 30.7 0.59 9.1 15.0 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein Topoisom_bac PF01131.15 EWM27014.1 - 4.8e-25 88.2 0.0 6e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EWM27014.1 - 6.8e-15 54.8 0.0 1e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Toprim domain Pox_T4_N PF04491.7 EWM27016.1 - 0.15 11.9 0.1 2.8 7.8 0.0 2.2 2 0 0 2 2 2 0 Poxvirus T4 protein, N terminus zf-CHCC PF10276.4 EWM27017.1 - 3e-13 49.3 1.0 4.1e-13 48.9 0.7 1.2 1 0 0 1 1 1 1 Zinc-finger domain zf-BED PF02892.10 EWM27017.1 - 0.056 13.2 0.1 0.096 12.4 0.1 1.3 1 0 0 1 1 1 0 BED zinc finger DUF1479 PF07350.7 EWM27018.1 - 8.2e-06 24.5 0.0 0.002 16.6 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1479) PhyH PF05721.8 EWM27018.1 - 0.036 14.1 0.1 5.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Coq4 PF05019.8 EWM27019.1 - 2.5e-81 271.8 0.0 3e-81 271.5 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 UDPGP PF01704.13 EWM27020.1 - 1.8e-40 138.7 0.0 5.2e-40 137.2 0.0 1.6 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 EWM27020.1 - 0.0083 16.2 0.6 0.031 14.3 0.1 2.3 2 1 0 2 2 2 1 MobA-like NTP transferase domain PP2C PF00481.16 EWM27021.1 - 4.1e-69 232.8 0.1 4.7e-69 232.6 0.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EWM27021.1 - 2.1e-08 33.8 0.0 5.7e-08 32.4 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EWM27021.1 - 0.00057 19.6 0.2 0.0015 18.3 0.2 1.8 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EWM27022.1 - 3e-57 193.9 0.1 3.8e-57 193.6 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EWM27022.1 - 2e-05 24.1 0.0 5.3e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EWM27022.1 - 0.0023 17.6 0.2 0.0059 16.3 0.1 1.8 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Surp PF01805.15 EWM27024.1 - 5e-13 48.4 0.0 1.1e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.17 EWM27024.1 - 3.6e-12 45.7 0.0 7.6e-12 44.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM27024.1 - 2.8e-10 40.0 0.0 6.1e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM27024.1 - 0.0012 18.6 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 EWM27024.1 - 0.024 14.8 0.0 0.055 13.7 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase II-binding domain. Hist_deacetyl PF00850.14 EWM27025.1 - 2.2e-67 227.5 0.0 4.9e-67 226.4 0.0 1.5 1 0 0 1 1 1 1 Histone deacetylase domain Ank PF00023.25 EWM27025.1 - 2.3e-29 99.6 11.0 4.6e-05 23.0 0.0 6.8 6 0 0 6 6 6 6 Ankyrin repeat Ank_2 PF12796.2 EWM27025.1 - 4e-29 100.7 22.1 1.6e-15 57.1 0.2 3.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EWM27025.1 - 2.7e-22 78.7 7.4 1.3e-06 28.7 0.1 6.3 4 2 3 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM27025.1 - 7.2e-22 75.2 4.2 0.0011 18.9 0.0 6.7 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 EWM27025.1 - 8.9e-22 76.6 7.0 3.1e-05 24.0 0.0 6.0 3 1 3 6 6 6 6 Ankyrin repeats (many copies) COPI_C PF06957.6 EWM27025.1 - 0.52 8.7 7.8 0.97 7.8 5.4 1.4 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Nop14 PF04147.7 EWM27025.1 - 0.63 7.9 16.4 0.88 7.4 11.4 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EWM27025.1 - 1.8 6.9 15.5 2.7 6.3 10.7 1.2 1 0 0 1 1 1 0 Daxx Family Cwf_Cwc_15 PF04889.7 EWM27025.1 - 2.5 7.7 9.9 4.5 6.9 6.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SR-25 PF10500.4 EWM27027.1 - 7.8 5.8 17.6 16 4.8 12.2 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Chloroa_b-bind PF00504.16 EWM27030.1 - 5.2e-44 150.2 0.1 7.2e-44 149.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DUF2360 PF10152.4 EWM27030.1 - 0.55 10.5 2.7 0.82 9.9 1.9 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Ribosomal_60s PF00428.14 EWM27030.1 - 4 7.9 11.4 7 7.1 7.9 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Pentapeptide_4 PF13599.1 EWM27031.1 - 2.4e-15 56.0 7.9 2.2e-10 40.2 1.7 2.0 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 EWM27031.1 - 2.3e-12 45.8 4.2 2.8e-09 35.9 1.0 3.1 3 1 0 3 3 3 2 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.1 EWM27031.1 - 2.2e-10 40.2 1.2 2.3e-06 27.3 0.2 3.3 1 1 2 3 3 3 2 Pentapeptide repeats (9 copies) CTP_transf_1 PF01148.15 EWM27032.1 - 2.3e-46 158.5 2.6 3.2e-46 158.1 1.8 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family BPD_transp_1 PF00528.17 EWM27032.1 - 0.51 9.8 5.7 0.2 11.1 0.2 2.4 2 1 0 2 2 2 0 Binding-protein-dependent transport system inner membrane component Rhomboid PF01694.17 EWM27033.1 - 9e-19 67.9 16.9 9e-19 67.9 11.7 1.7 2 0 0 2 2 2 1 Rhomboid family DER1 PF04511.10 EWM27033.1 - 0.00083 18.9 10.6 0.0013 18.3 7.4 1.3 1 0 0 1 1 1 1 Der1-like family DUF1751 PF08551.5 EWM27033.1 - 0.65 10.3 13.2 0.048 13.9 5.2 2.1 2 1 1 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) PRKCSH-like PF12999.2 EWM27035.1 - 1e-47 161.9 1.2 2.5e-47 160.6 0.9 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 EWM27035.1 - 2.2e-27 95.4 0.1 2.2e-27 95.4 0.1 1.6 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 EWM27035.1 - 0.00034 21.3 2.7 0.00036 21.2 0.5 2.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.13 EWM27035.1 - 0.017 15.0 10.1 0.023 14.6 1.2 2.6 1 1 1 2 2 2 0 Low-density lipoprotein receptor domain class A CENP-T PF15511.1 EWM27035.1 - 7 5.7 19.5 11 5.1 13.5 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T eIF-3c_N PF05470.7 EWM27036.1 - 2 6.4 5.0 2.8 5.9 3.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CDC45 PF02724.9 EWM27036.1 - 2.4 6.0 4.6 3.3 5.6 3.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Shisa PF13908.1 EWM27036.1 - 2.4 8.2 7.2 0.66 10.1 0.1 2.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Pro_isomerase PF00160.16 EWM27037.1 - 5.5e-34 117.6 0.0 6.9e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPT PF03151.11 EWM27038.1 - 3.1e-18 65.8 11.3 3.1e-18 65.8 7.8 2.3 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EWM27038.1 - 1.5e-07 30.6 17.3 1.9e-07 30.3 12.0 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EWM27038.1 - 0.0012 18.9 22.4 0.0078 16.2 6.3 2.3 2 0 0 2 2 2 2 EamA-like transporter family PseudoU_synth_2 PF00849.17 EWM27039.1 - 1.2e-13 51.1 0.0 2.1e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 EWM27039.1 - 1.9e-06 27.1 0.4 5.6e-06 25.6 0.1 2.0 2 0 0 2 2 2 1 S4 domain CCDC50_N PF15295.1 EWM27039.1 - 0.4 10.5 3.5 0.65 9.9 2.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus UDG PF03167.14 EWM27040.1 - 1.7e-26 92.4 0.0 3.5e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily BRCA2 PF00634.13 EWM27040.1 - 0.047 12.9 0.2 0.15 11.4 0.1 1.9 1 0 0 1 1 1 0 BRCA2 repeat Chloroa_b-bind PF00504.16 EWM27041.1 - 1.3e-30 106.7 0.1 1.7e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein PEPCK_ATP PF01293.15 EWM27042.1 - 1.5e-181 604.0 0.0 1.8e-181 603.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase PEPCK_ATP PF01293.15 EWM27043.1 - 5.3e-216 717.5 0.0 6.2e-216 717.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase GTP_EFTU PF00009.22 EWM27044.1 - 2.4e-38 131.4 0.1 4.2e-38 130.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EWM27044.1 - 5.4e-34 116.1 0.0 1.3e-33 114.8 0.0 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EWM27044.1 - 4.2e-13 49.1 3.3 7.2e-13 48.4 0.7 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EWM27044.1 - 0.0009 19.1 0.0 0.0019 18.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EWM27044.1 - 0.024 14.4 0.1 0.082 12.7 0.1 1.8 1 1 0 2 2 2 0 Dynamin family EamA PF00892.15 EWM27045.1 - 0.00029 20.8 7.9 0.00046 20.2 5.5 1.5 1 1 0 1 1 1 1 EamA-like transporter family EmrE PF13536.1 EWM27045.1 - 0.003 17.7 4.5 0.0036 17.4 3.1 1.2 1 0 0 1 1 1 1 Multidrug resistance efflux transporter UPF0546 PF10639.4 EWM27045.1 - 0.014 15.1 2.7 0.021 14.6 1.8 1.3 1 1 0 1 1 1 0 Uncharacterised protein family UPF0546 TPT PF03151.11 EWM27045.1 - 0.15 11.6 6.9 0.22 11.1 4.8 1.4 1 1 0 1 1 1 0 Triose-phosphate Transporter family zf-primase PF09329.6 EWM27046.1 - 0.15 11.6 0.3 0.47 10.0 0.0 1.9 2 1 0 2 2 2 0 Primase zinc finger WD40 PF00400.27 EWM27047.1 - 2.6e-21 74.6 4.1 1.5e-07 31.0 0.0 5.4 7 0 0 7 7 7 4 WD domain, G-beta repeat PQQ_3 PF13570.1 EWM27047.1 - 0.064 13.5 3.7 0.22 11.8 0.2 3.4 5 0 0 5 5 5 0 PQQ-like domain Acyltransferase PF01553.16 EWM27048.1 - 0.00016 21.1 0.0 0.00028 20.3 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Peptidase_M50 PF02163.17 EWM27049.1 - 1.8e-44 151.0 0.1 2.3e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M50 PDZ_2 PF13180.1 EWM27049.1 - 7e-10 38.6 0.0 1.4e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 EWM27049.1 - 5e-05 23.3 0.0 0.00015 21.9 0.0 1.8 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) GRASP55_65 PF04495.9 EWM27049.1 - 0.091 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain Tricorn_PDZ PF14685.1 EWM27049.1 - 0.12 12.2 0.1 0.34 10.7 0.0 1.8 1 0 0 1 1 1 0 Tricorn protease PDZ domain Sulfate_transp PF00916.15 EWM27049.1 - 0.18 10.7 3.2 0.099 11.6 0.8 1.6 2 0 0 2 2 2 0 Sulfate transporter family Glyco_hydro_47 PF01532.15 EWM27051.1 - 1.6e-144 481.9 0.0 2e-144 481.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 ATP_synt_H PF05493.8 EWM27052.1 - 0.042 13.9 2.1 0.049 13.7 0.2 2.0 2 0 0 2 2 2 0 ATP synthase subunit H SID-1_RNA_chan PF13965.1 EWM27053.1 - 0.22 9.6 0.3 0.36 8.9 0.2 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 NVEALA PF14055.1 EWM27054.1 - 0.12 12.0 0.0 0.41 10.3 0.0 1.9 1 0 0 1 1 1 0 NVEALA protein Enkurin PF13864.1 EWM27054.1 - 0.18 12.0 1.6 10 6.3 0.0 2.3 2 0 0 2 2 2 0 Calmodulin-binding HIRA_B PF09453.5 EWM27055.1 - 0.067 12.7 0.4 0.18 11.4 0.3 1.8 1 0 0 1 1 1 0 HIRA B motif SR-25 PF10500.4 EWM27055.1 - 3.1 7.2 10.9 9.6 5.6 7.5 1.9 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Med3 PF11593.3 EWM27056.1 - 9.3 5.3 5.9 13 4.8 4.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal NUDIX PF00293.23 EWM27059.1 - 7.5e-15 54.7 0.2 1.2e-14 54.1 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain DUF3446 PF11928.3 EWM27059.1 - 0.081 13.1 1.6 0.15 12.2 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) DUF1631 PF07793.6 EWM27060.1 - 0.32 9.0 3.0 0.35 8.9 2.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) PAT1 PF09770.4 EWM27060.1 - 0.62 8.2 16.2 0.74 7.9 11.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 EWM27060.1 - 5.8 6.1 12.0 7 5.9 8.3 1.1 1 0 0 1 1 1 0 Vta1 like VPS9 PF02204.13 EWM27062.1 - 1.8e-11 43.9 0.0 3.4e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PfkB PF00294.19 EWM27063.1 - 2.5e-42 145.0 0.0 1.8e-27 96.2 0.0 2.0 2 0 0 2 2 2 2 pfkB family carbohydrate kinase DUF2953 PF11167.3 EWM27063.1 - 0.058 13.2 0.2 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) Gln-synt_C PF00120.19 EWM27066.1 - 7.3e-51 172.8 0.0 9.8e-51 172.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EWM27066.1 - 2.9e-21 74.8 0.0 5.5e-21 73.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Aminotran_5 PF00266.14 EWM27067.1 - 1.4e-148 494.6 0.0 1.6e-148 494.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EWM27067.1 - 1.6e-05 24.0 0.0 3e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EWM27067.1 - 0.00032 19.1 0.1 0.0017 16.7 0.0 1.8 1 1 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme TPR_11 PF13414.1 EWM27069.1 - 5.1e-29 99.7 20.6 1e-14 53.8 1.3 5.5 3 2 2 5 5 5 3 TPR repeat DnaJ PF00226.26 EWM27069.1 - 1.1e-22 79.4 0.0 2.5e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.23 EWM27069.1 - 1e-17 62.9 20.1 8.2e-05 22.0 0.1 7.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 EWM27069.1 - 9e-14 50.2 35.3 0.00069 19.3 0.6 7.7 9 0 0 9 9 7 5 Tetratricopeptide repeat TPR_19 PF14559.1 EWM27069.1 - 2.4e-05 24.5 4.3 0.077 13.3 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EWM27069.1 - 0.00055 20.5 25.6 0.04 14.6 0.2 6.0 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EWM27069.1 - 0.0015 18.4 0.5 0.0015 18.4 0.4 5.9 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 EWM27069.1 - 0.004 16.9 15.4 0.19 11.5 0.5 5.3 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EWM27069.1 - 0.037 14.2 0.2 43 4.6 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 EWM27069.1 - 0.056 13.2 13.9 0.76 9.6 0.1 5.8 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 EWM27069.1 - 0.36 10.7 6.2 6.1 6.9 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EWM27069.1 - 0.55 11.0 20.9 9.9 7.1 0.3 6.5 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.1 EWM27070.1 - 2.1e-22 78.5 16.9 0.002 17.7 0.0 9.9 7 2 5 12 12 12 8 TPR repeat TPR_16 PF13432.1 EWM27070.1 - 2.4e-22 79.0 71.2 2.4e-06 28.0 0.0 13.5 10 2 5 15 15 13 7 Tetratricopeptide repeat TPR_12 PF13424.1 EWM27070.1 - 9.4e-20 70.3 27.0 0.001 18.9 0.1 9.1 7 2 3 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.12 EWM27070.1 - 4.7e-17 60.4 29.5 0.0072 16.1 0.0 12.8 14 0 0 14 14 12 5 Tetratricopeptide repeat TPR_1 PF00515.23 EWM27070.1 - 8.7e-16 56.7 7.3 0.047 13.3 0.0 9.9 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_19 PF14559.1 EWM27070.1 - 9.3e-14 51.5 32.4 0.01 16.1 0.1 10.8 7 4 5 12 12 12 8 Tetratricopeptide repeat TPR_6 PF13174.1 EWM27070.1 - 1.8e-10 40.5 12.9 0.62 10.6 0.0 11.4 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_14 PF13428.1 EWM27070.1 - 2.1e-10 40.2 62.9 0.15 12.8 0.0 15.9 8 6 10 18 18 16 5 Tetratricopeptide repeat TPR_8 PF13181.1 EWM27070.1 - 1.1e-08 34.2 3.7 1.3 8.9 0.0 7.7 8 1 0 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 EWM27070.1 - 3.8e-08 32.9 4.9 17 5.9 0.0 10.4 11 0 0 11 11 10 0 Tetratricopeptide repeat TPR_7 PF13176.1 EWM27070.1 - 8.4e-06 25.2 8.6 8 6.5 0.0 8.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.1 EWM27070.1 - 3.6e-05 23.5 24.7 0.11 12.3 0.6 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat NARP1 PF12569.3 EWM27070.1 - 9.1e-05 21.3 17.2 0.0031 16.3 0.0 4.8 6 0 0 6 6 6 2 NMDA receptor-regulated protein 1 Apc3 PF12895.2 EWM27070.1 - 0.00038 20.5 12.6 3.9 7.6 0.5 6.1 4 3 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 Folliculin PF11704.3 EWM27070.1 - 0.13 11.7 1.6 0.27 10.7 1.1 1.4 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport OmpH PF03938.9 EWM27070.1 - 1.3 8.9 13.1 3.2 7.6 9.1 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RNase_H2-Ydr279 PF09468.5 EWM27070.1 - 2.2 7.4 2.8 3.5 6.7 1.9 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Macoilin PF09726.4 EWM27070.1 - 5.1 5.2 14.8 7.8 4.6 10.3 1.2 1 0 0 1 1 1 0 Transmembrane protein Leader_Trp PF08255.6 EWM27074.1 - 0.47 10.2 2.7 0.35 10.6 0.2 2.0 2 0 0 2 2 2 0 Trp-operon Leader Peptide Ribosomal_S17 PF00366.15 EWM27075.1 - 1.2e-20 73.2 1.4 1.8e-20 72.7 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 FAD_binding_3 PF01494.14 EWM27076.1 - 3e-19 69.3 0.4 7.2e-19 68.0 0.3 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EWM27076.1 - 6.3e-05 22.9 0.1 0.00017 21.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EWM27076.1 - 0.0026 16.7 0.5 1.7 7.4 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EWM27076.1 - 0.0084 16.5 0.1 1.6 9.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EWM27076.1 - 0.017 15.0 0.2 0.04 13.7 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AFG1_ATPase PF03969.11 EWM27077.1 - 1.7e-86 290.2 0.1 2.5e-56 191.0 0.1 3.8 2 1 1 3 3 3 3 AFG1-like ATPase AAA_16 PF13191.1 EWM27077.1 - 0.00053 20.0 0.7 0.00053 20.0 0.5 3.1 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EWM27077.1 - 0.0007 19.7 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EWM27077.1 - 0.0082 15.1 0.0 0.029 13.3 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 EWM27077.1 - 0.02 15.0 0.0 0.061 13.5 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRC-1 PF08832.5 EWM27077.1 - 0.064 13.9 1.1 0.12 13.1 0.7 1.4 1 0 0 1 1 1 0 Steroid receptor coactivator AAA_5 PF07728.9 EWM27077.1 - 0.093 12.4 0.1 0.53 10.0 0.1 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) FAM117 PF15388.1 EWM27078.1 - 0.073 12.2 5.5 0.097 11.8 3.8 1.2 1 0 0 1 1 1 0 Protein Family FAM117 Shisa PF13908.1 EWM27078.1 - 3.5 7.7 10.1 5.1 7.2 7.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4336 PF14234.1 EWM27079.1 - 1.1e-87 293.8 0.0 1.3e-87 293.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4336) TP_methylase PF00590.15 EWM27080.1 - 8.5e-30 104.0 0.5 1.2e-29 103.5 0.3 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF3356 PF11836.3 EWM27080.1 - 0.038 13.7 0.5 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3356) Zn_clus PF00172.13 EWM27081.1 - 1.3e-07 31.3 10.0 1.3e-07 31.3 7.0 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 EWM27082.1 - 1.1e-37 129.6 0.0 1.7e-37 129.0 0.0 1.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM27082.1 - 7.3e-13 48.1 0.0 1.1e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EWM27082.1 - 0.0021 17.8 0.1 0.02 14.6 0.0 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family tRNA-synt_His PF13393.1 EWM27083.1 - 1.3e-46 159.0 0.0 1.9e-46 158.5 0.0 1.2 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EWM27083.1 - 2.6e-18 66.2 0.0 3.8e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EWM27083.1 - 3.2e-13 49.4 0.0 5.6e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2d PF01409.15 EWM27083.1 - 0.0044 16.2 0.0 0.0077 15.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_His PF13393.1 EWM27084.1 - 1.3e-46 159.0 0.0 1.9e-46 158.5 0.0 1.2 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EWM27084.1 - 2.6e-18 66.2 0.0 3.8e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EWM27084.1 - 3.3e-13 49.3 0.0 5.6e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2d PF01409.15 EWM27084.1 - 0.0044 16.2 0.0 0.0077 15.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) ABC_tran PF00005.22 EWM27085.1 - 4.5e-50 169.5 0.1 1.1e-26 93.7 0.0 3.1 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 EWM27085.1 - 1.8e-23 83.9 0.2 8.3e-11 42.3 0.0 4.3 3 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 EWM27085.1 - 3.8e-10 39.3 0.7 0.0044 16.2 0.0 4.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_tran_2 PF12848.2 EWM27085.1 - 9.1e-10 38.2 12.0 1.2e-09 37.8 3.3 3.4 3 0 0 3 3 3 1 ABC transporter AAA_33 PF13671.1 EWM27085.1 - 8.9e-07 28.8 0.0 0.00096 19.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EWM27085.1 - 1.1e-06 27.9 0.1 0.046 12.9 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 EWM27085.1 - 2.6e-06 26.8 3.5 0.015 14.7 0.1 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain ArgK PF03308.11 EWM27085.1 - 4.5e-06 25.6 0.1 0.014 14.2 0.0 2.5 2 0 0 2 2 2 2 ArgK protein Miro PF08477.8 EWM27085.1 - 3e-05 24.5 2.6 0.47 10.9 0.0 3.8 4 0 0 4 4 4 2 Miro-like protein AAA_17 PF13207.1 EWM27085.1 - 4e-05 24.4 0.6 0.042 14.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 EWM27085.1 - 4e-05 23.5 0.2 0.51 10.3 0.0 2.9 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_15 PF13175.1 EWM27085.1 - 5.8e-05 22.3 0.0 2.5 7.0 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.1 EWM27085.1 - 6.9e-05 23.2 16.4 0.037 14.3 0.4 4.2 3 1 1 4 4 4 2 AAA domain AAA_22 PF13401.1 EWM27085.1 - 0.00012 22.2 7.7 3.2 7.9 0.9 4.6 4 1 0 4 4 3 1 AAA domain Dynamin_N PF00350.18 EWM27085.1 - 0.00067 19.5 1.6 0.9 9.3 0.1 3.0 3 0 0 3 3 2 2 Dynamin family ATP-synt_ab PF00006.20 EWM27085.1 - 0.0011 18.4 0.0 0.19 11.2 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.1 EWM27085.1 - 0.0016 17.8 0.5 2 7.7 0.0 3.0 3 0 0 3 3 3 2 AAA domain NACHT PF05729.7 EWM27085.1 - 0.0021 17.7 0.1 1.2 8.7 0.0 2.5 2 0 0 2 2 2 1 NACHT domain MobB PF03205.9 EWM27085.1 - 0.0029 17.3 0.4 0.43 10.2 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EWM27085.1 - 0.0033 16.9 1.6 2.2 7.6 0.0 3.7 4 1 0 4 4 4 1 AAA-like domain AAA PF00004.24 EWM27085.1 - 0.013 15.7 0.2 19 5.4 0.1 3.6 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EWM27085.1 - 0.016 15.0 1.3 7.1 6.5 0.1 3.5 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 EWM27085.1 - 0.029 14.3 12.0 0.35 10.8 0.0 3.9 2 1 1 3 3 3 0 AAA ATPase domain AAA_18 PF13238.1 EWM27085.1 - 0.03 14.6 0.1 8.5 6.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain MutS_V PF00488.16 EWM27085.1 - 0.047 13.0 0.6 12 5.2 0.0 3.0 2 1 0 3 3 3 0 MutS domain V Arch_ATPase PF01637.13 EWM27085.1 - 0.054 13.1 1.9 25 4.4 0.0 3.2 2 1 1 3 3 3 0 Archaeal ATPase T2SE PF00437.15 EWM27085.1 - 0.11 11.3 0.3 1.6 7.5 0.0 2.8 4 0 0 4 4 4 0 Type II/IV secretion system protein Mg_chelatase PF01078.16 EWM27085.1 - 0.14 11.2 0.0 2.6 7.1 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EWM27085.1 - 0.19 11.9 0.3 11 6.2 0.0 2.4 2 0 0 2 2 2 0 RNA helicase IncA PF04156.9 EWM27085.1 - 0.33 10.5 9.2 0.52 9.8 0.4 2.3 2 0 0 2 2 2 0 IncA protein DUF87 PF01935.12 EWM27085.1 - 0.35 10.6 2.5 1.9 8.2 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 NB-ARC PF00931.17 EWM27085.1 - 0.91 8.3 5.0 2.3 6.9 0.1 2.9 3 0 0 3 3 3 0 NB-ARC domain Peptidase_S41 PF03572.13 EWM27086.1 - 7.9e-45 152.2 0.9 1.3e-44 151.5 0.6 1.4 1 0 0 1 1 1 1 Peptidase family S41 PDZ PF00595.19 EWM27086.1 - 1.1e-09 38.3 0.0 2.2e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EWM27086.1 - 7.8e-07 28.8 0.1 1.9e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.1 EWM27086.1 - 0.013 15.3 0.2 0.041 13.6 0.0 1.9 2 0 0 2 2 2 0 Tricorn protease PDZ domain Tricorn_C1 PF14684.1 EWM27086.1 - 0.017 14.9 0.2 0.03 14.2 0.1 1.3 1 0 0 1 1 1 0 Tricorn protease C1 domain 2OG-FeII_Oxy_2 PF13532.1 EWM27087.1 - 9.5e-11 41.8 0.0 1.5e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Frataxin_Cyay PF01491.11 EWM27088.1 - 5.5e-31 106.5 0.0 4.5e-30 103.6 0.0 1.9 2 0 0 2 2 2 1 Frataxin-like domain ABC2_membrane PF01061.19 EWM27089.1 - 2.7e-22 78.9 24.5 2.7e-22 78.9 17.0 2.0 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 EWM27089.1 - 5.6e-20 72.0 0.0 8.5e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EWM27089.1 - 3.9e-07 30.3 0.0 0.012 15.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EWM27089.1 - 0.0011 18.2 0.0 0.0018 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EWM27089.1 - 0.0018 18.3 0.1 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EWM27089.1 - 0.0046 16.3 0.1 0.035 13.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EWM27089.1 - 0.0046 16.4 0.3 0.011 15.2 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EWM27089.1 - 0.005 17.2 0.1 0.0074 16.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EWM27089.1 - 0.0076 16.2 0.1 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EWM27089.1 - 0.012 15.8 0.1 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 EWM27089.1 - 0.03 13.3 0.0 0.046 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain cobW PF02492.14 EWM27089.1 - 0.067 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.14 EWM27089.1 - 0.1 11.8 0.0 3.9 6.6 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.2 EWM27089.1 - 3.2 6.7 31.3 0.09 11.7 14.7 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF1242 PF06842.7 EWM27090.1 - 1.8e-10 40.0 0.2 3.3e-10 39.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) OMPdecase PF00215.19 EWM27091.1 - 5.9e-28 97.7 0.0 2.4e-27 95.7 0.0 1.9 1 1 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.22 EWM27091.1 - 1.7e-17 63.2 0.4 3.6e-17 62.2 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain ThiG PF05690.9 EWM27091.1 - 0.016 14.2 0.3 0.63 9.0 0.2 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG E2F_TDP PF02319.15 EWM27092.1 - 7e-23 79.9 0.1 1.3e-22 79.0 0.1 1.5 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain DUF4423 PF14394.1 EWM27092.1 - 0.013 15.0 0.4 0.019 14.4 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) TrmB PF01978.14 EWM27092.1 - 0.13 11.9 0.1 0.37 10.5 0.1 1.7 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB CBF PF03914.12 EWM27094.1 - 8.3e-28 96.8 0.2 3.2e-26 91.7 0.0 3.2 3 1 0 3 3 3 1 CBF/Mak21 family Adaptin_N PF01602.15 EWM27094.1 - 0.051 11.8 0.0 0.13 10.5 0.0 1.5 2 0 0 2 2 2 0 Adaptin N terminal region HEAT_2 PF13646.1 EWM27094.1 - 0.61 10.4 11.3 1.9 8.8 0.3 3.8 3 1 1 4 4 4 0 HEAT repeats Acyl_transf_1 PF00698.16 EWM27095.1 - 1.5e-31 109.9 0.3 1.9e-31 109.6 0.2 1.1 1 0 0 1 1 1 1 Acyl transferase domain SQS_PSY PF00494.14 EWM27096.1 - 2.5e-51 174.5 2.0 2.9e-51 174.3 1.4 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase DNA_ligase_A_N PF04675.9 EWM27097.1 - 6.4e-23 81.4 0.0 9e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.16 EWM27097.1 - 7.6e-19 67.8 0.0 1.9e-18 66.5 0.0 1.7 2 0 0 2 2 2 1 ATP dependent DNA ligase domain Lipase_3 PF01764.20 EWM27098.1 - 5.2e-17 61.7 0.1 9.8e-17 60.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EWM27098.1 - 0.018 14.8 0.1 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM27098.1 - 0.023 14.4 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.3 EWM27098.1 - 0.056 12.8 0.0 0.85 8.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) PGAP1 PF07819.8 EWM27098.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DAO PF01266.19 EWM27099.1 - 7e-18 64.6 2.4 1.1e-17 63.9 1.7 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EWM27099.1 - 9.2e-05 22.3 0.0 0.00025 21.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EWM27099.1 - 0.002 17.0 0.1 0.0035 16.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EWM27099.1 - 0.0024 18.2 0.0 0.0045 17.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EWM27099.1 - 0.0029 17.5 0.0 0.19 11.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EWM27099.1 - 0.0046 16.7 0.2 0.021 14.5 0.1 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 EWM27099.1 - 0.12 11.9 0.3 0.35 10.4 0.0 1.9 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain G0-G1_switch_2 PF15103.1 EWM27099.1 - 0.13 12.5 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 GIDA PF01134.17 EWM27099.1 - 0.15 10.9 0.2 0.24 10.2 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A MT0933_antitox PF14013.1 EWM27100.1 - 0.0084 16.1 2.5 0.63 10.1 0.1 3.2 2 1 1 3 3 3 2 MT0933-like antitoxin protein DUF2277 PF10041.4 EWM27100.1 - 0.058 13.3 0.1 0.17 11.8 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2277) MT0933_antitox PF14013.1 EWM27101.1 - 0.0095 16.0 2.6 0.64 10.1 0.1 3.2 2 1 1 3 3 3 2 MT0933-like antitoxin protein DUF2277 PF10041.4 EWM27101.1 - 0.058 13.3 0.1 0.18 11.8 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2277) LETM1 PF07766.8 EWM27102.1 - 1e-20 73.9 0.0 3.2e-20 72.2 0.0 1.7 1 1 0 1 1 1 1 LETM1-like protein Ion_trans PF00520.26 EWM27103.1 - 2.1e-20 72.8 8.9 3.6e-20 72.0 6.2 1.4 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.11 EWM27103.1 - 1.4e-05 24.7 6.5 4.3e-05 23.1 4.5 1.9 1 1 0 1 1 1 1 Ion channel HR1 PF02185.11 EWM27103.1 - 0.044 13.5 0.2 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 Hr1 repeat ABC1 PF03109.11 EWM27104.1 - 9.1e-34 115.9 0.0 1.8e-33 115.0 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 EWM27104.1 - 0.0037 17.0 2.3 0.0075 16.0 0.2 2.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EWM27104.1 - 0.16 11.3 0.0 0.6 9.4 0.0 1.8 2 0 0 2 2 2 0 RIO1 family NOSIC PF08060.8 EWM27104.1 - 0.22 11.3 0.8 0.67 9.8 0.0 2.1 3 0 0 3 3 3 0 NOSIC (NUC001) domain zf-C2H2 PF00096.21 EWM27105.1 - 3.8e-21 74.0 17.0 4.6e-05 23.5 0.1 5.0 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EWM27105.1 - 4.7e-17 61.3 26.4 4.8e-06 26.6 0.5 6.1 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EWM27105.1 - 7.9e-15 54.0 22.4 0.00066 19.8 0.1 5.6 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EWM27105.1 - 1.9e-09 37.3 2.4 0.44 10.7 0.0 4.9 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EWM27105.1 - 1.3e-06 28.4 5.9 0.0027 17.8 0.1 4.6 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-BED PF02892.10 EWM27105.1 - 0.011 15.5 4.7 0.12 12.1 0.8 3.1 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.1 EWM27105.1 - 0.012 15.5 14.2 0.95 9.4 0.1 4.6 5 0 0 5 5 5 0 C2H2-type zinc finger Elf1 PF05129.8 EWM27105.1 - 0.022 14.4 1.4 0.053 13.2 0.2 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-CHY PF05495.7 EWM27105.1 - 0.035 14.2 2.4 0.12 12.5 0.6 2.8 1 1 1 2 2 2 0 CHY zinc finger zf-LYAR PF08790.6 EWM27105.1 - 0.99 9.1 4.5 3 7.6 0.1 3.5 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger CRAL_TRIO PF00650.15 EWM27106.1 - 3.5e-15 55.8 0.0 5.1e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EWM27106.1 - 0.032 14.1 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain TP_methylase PF00590.15 EWM27107.1 - 2e-19 70.1 0.1 5.5e-19 68.7 0.1 1.7 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Tim17 PF02466.14 EWM27108.1 - 6.7e-11 42.3 5.8 7.9e-11 42.0 4.0 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_OmpA PF13436.1 EWM27108.1 - 0.0028 17.2 0.8 0.12 11.9 1.2 2.1 2 0 0 2 2 2 1 Glycine-zipper containing OmpA-like membrane domain DUF1212 PF06738.7 EWM27108.1 - 0.051 13.0 0.5 0.084 12.3 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) DUF3767 PF12597.3 EWM27108.1 - 0.11 12.1 1.8 0.2 11.3 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) PhyH PF05721.8 EWM27109.1 - 4.4e-25 88.9 0.0 5.7e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DTW PF03942.10 EWM27110.1 - 2.1e-11 43.3 0.1 3e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 DTW domain RRM_1 PF00076.17 EWM27111.1 - 2.5e-11 43.0 0.0 0.00029 20.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM27111.1 - 2.6e-08 33.6 0.0 2.4e-07 30.6 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM27111.1 - 0.00035 20.3 0.1 0.0022 17.8 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HHH_5 PF14520.1 EWM27111.1 - 0.015 15.4 0.1 0.075 13.2 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix domain TauD PF02668.11 EWM27111.1 - 0.16 11.6 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family Ebp2 PF05890.7 EWM27114.1 - 4.5e-63 213.0 6.9 7.2e-63 212.4 4.8 1.3 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 DUF2098 PF09871.4 EWM27114.1 - 8.4 6.3 7.8 0.97 9.4 2.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) Actin PF00022.14 EWM27115.1 - 4.4e-40 137.3 0.0 1e-29 103.1 0.0 3.1 2 1 1 3 3 3 3 Actin DUF760 PF05542.6 EWM27116.1 - 5.2e-21 74.6 0.3 2.1e-10 40.6 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF760) Form_Nir_trans PF01226.12 EWM27117.1 - 3.2e-66 222.7 25.3 3.8e-66 222.5 17.5 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter DUF373 PF04123.8 EWM27117.1 - 1.1 8.2 8.1 1.5 7.7 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) 3Beta_HSD PF01073.14 EWM27119.1 - 6.7e-65 218.5 0.0 8.5e-65 218.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EWM27119.1 - 6e-38 130.6 0.1 8.3e-38 130.1 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EWM27119.1 - 1.2e-23 84.1 0.9 1.8e-23 83.5 0.6 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EWM27119.1 - 3.1e-18 65.5 1.1 1.6e-14 53.4 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein Cyt-b5 PF00173.23 EWM27119.1 - 3.5e-18 65.1 0.4 2.5e-17 62.4 0.1 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain RmlD_sub_bind PF04321.12 EWM27119.1 - 3.8e-12 45.6 0.2 4.9e-12 45.3 0.1 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EWM27119.1 - 8.2e-07 28.2 3.8 3.6e-06 26.0 2.6 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EWM27119.1 - 4.8e-06 26.5 2.3 0.0075 16.2 1.6 2.3 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EWM27119.1 - 4.2e-05 22.9 1.9 7e-05 22.1 1.4 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 EWM27119.1 - 0.0044 16.6 3.0 1.1 8.9 0.2 2.4 1 1 0 2 2 2 2 KR domain NAD_binding_7 PF13241.1 EWM27119.1 - 0.084 13.1 0.1 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ASC PF00858.19 EWM27123.1 - 1.9 7.0 4.9 4.2 5.9 3.4 1.8 1 1 0 1 1 1 0 Amiloride-sensitive sodium channel Cupin_8 PF13621.1 EWM27124.1 - 1.8e-18 66.9 0.2 4.6e-18 65.6 0.1 1.5 1 1 0 1 1 1 1 Cupin-like domain Sulfotransfer_3 PF13469.1 EWM27124.1 - 1.3e-06 29.3 1.3 2e-05 25.5 0.0 2.6 2 0 0 2 2 2 1 Sulfotransferase family Peptidase_S8 PF00082.17 EWM27126.1 - 3.7e-25 88.6 1.0 5.9e-25 87.9 0.0 1.7 2 0 0 2 2 2 1 Subtilase family MT-A70 PF05063.9 EWM27127.1 - 8.9e-40 136.0 0.1 4e-39 133.9 0.0 2.0 1 1 0 1 1 1 1 MT-A70 Cons_hypoth95 PF03602.10 EWM27127.1 - 0.054 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 LSM PF01423.17 EWM27128.1 - 1.1e-19 69.7 0.4 1.5e-19 69.2 0.3 1.2 1 0 0 1 1 1 1 LSM domain CFEM PF05730.6 EWM27129.1 - 0.0057 16.4 1.6 0.029 14.2 1.1 2.3 1 0 0 1 1 1 1 CFEM domain DUF829 PF05705.9 EWM27130.1 - 3.3e-31 108.8 0.2 8e-31 107.5 0.1 1.6 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Aminotran_3 PF00202.16 EWM27131.1 - 2.8e-109 365.0 0.0 3.5e-109 364.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 EWM27131.1 - 0.012 14.7 0.0 0.043 12.9 0.0 1.9 2 1 0 2 2 2 0 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EWM27131.1 - 0.15 10.9 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Tyrosinase PF00264.15 EWM27132.1 - 4.3e-32 112.0 2.4 1.7e-31 110.1 1.6 2.0 1 1 0 1 1 1 1 Common central domain of tyrosinase CBM_1 PF00734.13 EWM27132.1 - 8.1e-07 28.5 11.9 1.7e-06 27.5 8.3 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain ALAD PF00490.16 EWM27133.1 - 1.5e-144 480.8 0.0 1.8e-144 480.5 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase EF1_GNE PF00736.14 EWM27134.1 - 1.2e-31 108.2 1.4 1.9e-31 107.5 0.9 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain GST_C_3 PF14497.1 EWM27134.1 - 0.023 15.1 0.0 0.058 13.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain EF-1_beta_acid PF10587.4 EWM27134.1 - 0.53 10.4 4.8 0.37 10.9 1.5 2.2 1 1 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Stm1_N PF09598.5 EWM27134.1 - 6.3 7.5 8.2 0.29 11.8 1.4 2.0 2 0 0 2 2 2 0 Stm1 DUF2098 PF09871.4 EWM27134.1 - 9 6.3 7.3 7.5 6.5 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) AAA PF00004.24 EWM27136.1 - 1.7e-42 144.7 0.0 3e-42 143.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EWM27136.1 - 5.3e-06 26.5 0.0 6.2e-05 23.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EWM27136.1 - 1.5e-05 25.1 0.3 0.00051 20.0 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EWM27136.1 - 1.9e-05 25.4 0.0 4.3e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EWM27136.1 - 0.00015 21.7 0.0 0.00028 20.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EWM27136.1 - 0.00033 19.7 0.0 0.00094 18.2 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EWM27136.1 - 0.00039 20.1 0.1 0.0013 18.4 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 EWM27136.1 - 0.00049 18.9 0.0 0.00082 18.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_2 PF07724.9 EWM27136.1 - 0.0014 18.5 0.0 0.0027 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EWM27136.1 - 0.0022 17.7 0.3 0.049 13.3 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EWM27136.1 - 0.0029 16.5 0.0 0.0072 15.2 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 EWM27136.1 - 0.0036 16.4 0.0 0.0063 15.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 EWM27136.1 - 0.0042 16.9 0.0 0.013 15.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EWM27136.1 - 0.0072 16.6 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EWM27136.1 - 0.0096 15.3 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 EWM27136.1 - 0.014 15.3 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EWM27136.1 - 0.062 12.7 0.4 1.7 8.0 0.3 2.2 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EWM27136.1 - 0.063 12.4 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EWM27136.1 - 0.076 12.6 0.1 0.35 10.5 0.1 2.1 1 1 0 1 1 1 0 NACHT domain DUF2075 PF09848.4 EWM27136.1 - 0.077 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.1 EWM27136.1 - 0.081 12.9 0.0 0.3 11.1 0.0 2.0 1 1 1 2 2 2 0 Sigma-54 interaction domain FtsH_ext PF06480.10 EWM27136.1 - 0.09 12.9 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 FtsH Extracellular AAA_3 PF07726.6 EWM27136.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF3414 PF11894.3 EWM27138.1 - 0.037 10.9 0.1 0.036 10.9 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3414) Sugar_tr PF00083.19 EWM27139.1 - 2.9e-99 332.6 22.9 3.7e-99 332.3 15.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EWM27139.1 - 1.9e-34 118.9 28.0 5.1e-31 107.6 20.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Bac_luciferase PF00296.15 EWM27139.1 - 0.14 11.2 1.3 0.14 11.2 0.1 1.5 2 0 0 2 2 2 0 Luciferase-like monooxygenase Ald_Xan_dh_C2 PF02738.13 EWM27140.1 - 3.4e-133 444.8 0.0 6.2e-133 444.0 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Fer2_2 PF01799.15 EWM27140.1 - 4.4e-24 84.1 0.2 1e-23 83.0 0.1 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain FAD_binding_5 PF00941.16 EWM27140.1 - 2.2e-17 63.0 0.0 1.9e-16 60.0 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.17 EWM27140.1 - 2.6e-17 62.8 0.0 6.9e-17 61.5 0.0 1.8 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain FAD_binding_3 PF01494.14 EWM27140.1 - 2.4e-15 56.4 0.0 5.9e-08 32.1 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain CO_deh_flav_C PF03450.12 EWM27140.1 - 2.5e-09 37.0 1.6 2.5e-09 37.0 1.1 3.9 4 1 0 4 4 4 1 CO dehydrogenase flavoprotein C-terminal domain Ribosomal_S30AE PF02482.14 EWM27140.1 - 0.39 11.1 0.0 2.7 8.4 0.0 2.2 2 0 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein HALZ PF02183.13 EWM27141.1 - 1.2 8.9 9.2 0.54 10.0 0.9 3.7 4 0 0 4 4 4 0 Homeobox associated leucine zipper NTF2 PF02136.15 EWM27142.1 - 1.4e-22 80.3 0.0 1.5e-22 80.1 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Sec7 PF01369.15 EWM27144.1 - 8e-62 208.2 0.0 1.6e-61 207.2 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EWM27144.1 - 3.4e-45 153.4 1.8 3.4e-45 153.4 1.2 3.1 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EWM27144.1 - 2.3e-29 100.7 0.4 3.3e-28 97.0 0.1 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) B56 PF01603.15 EWM27144.1 - 3.8 5.9 6.8 0.84 8.1 0.6 2.3 2 0 0 2 2 2 0 Protein phosphatase 2A regulatory B subunit (B56 family) PH PF00169.24 EWM27145.1 - 8.4e-19 67.7 0.1 1.1e-18 67.3 0.1 1.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EWM27145.1 - 1.2e-09 38.4 1.9 1.3e-08 35.1 1.3 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 EWM27145.1 - 0.00095 19.0 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 EWM27145.1 - 0.0021 18.0 0.1 0.0032 17.4 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.1 EWM27145.1 - 0.015 15.4 0.2 0.52 10.4 0.0 2.1 1 1 1 2 2 2 0 Pleckstrin homology domain YL1_C PF08265.6 EWM27145.1 - 0.025 14.1 0.1 0.048 13.2 0.1 1.5 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain PH_6 PF15406.1 EWM27145.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain Ribonuclease_3 PF00636.21 EWM27146.1 - 1.7e-28 99.3 0.0 6.6e-13 49.1 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EWM27146.1 - 1.2e-21 76.9 0.0 6.2e-10 39.1 0.0 3.4 3 1 0 3 3 3 2 Ribonuclease-III-like DEAD PF00270.24 EWM27146.1 - 5e-15 55.3 0.0 9.1e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EWM27146.1 - 1.7e-13 50.2 0.0 4.7e-13 48.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EWM27146.1 - 2.2e-09 37.3 0.0 4.2e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.12 EWM27146.1 - 1.4e-05 24.5 0.3 7.1e-05 22.3 0.0 2.2 3 0 0 3 3 3 1 IstB-like ATP binding protein Dicer_dimer PF03368.9 EWM27146.1 - 4.5e-05 23.1 0.0 0.00015 21.4 0.0 1.9 1 0 0 1 1 1 1 Dicer dimerisation domain AAA_22 PF13401.1 EWM27146.1 - 0.00038 20.5 0.1 0.0014 18.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EWM27146.1 - 0.063 12.2 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Thioredoxin PF00085.15 EWM27147.1 - 1e-24 86.2 0.0 1.2e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EWM27147.1 - 1.1e-10 41.6 0.0 7.4e-10 39.0 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EWM27147.1 - 2.1e-09 37.2 0.0 3.1e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.1 EWM27147.1 - 0.00013 22.0 0.0 0.00032 20.7 0.0 1.5 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.16 EWM27147.1 - 0.00083 19.0 0.0 0.0032 17.1 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EWM27147.1 - 0.0069 15.9 0.0 0.013 15.0 0.0 1.5 1 1 0 1 1 1 1 Redoxin Thioredox_DsbH PF03190.10 EWM27147.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF255 DUF1995 PF09353.5 EWM27148.1 - 4.1e-20 72.2 0.0 5.5e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) Vps54 PF07928.7 EWM27149.1 - 4.8e-41 140.0 3.1 1.2e-40 138.7 2.2 1.7 1 0 0 1 1 1 1 Vps54-like protein DUF2450 PF10475.4 EWM27149.1 - 9.6e-09 34.5 0.0 2e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 EWM27149.1 - 0.0066 16.3 1.1 0.35 10.7 0.7 2.9 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF1491 PF07372.7 EWM27150.1 - 0.0069 16.2 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1491) PIG-P PF08510.7 EWM27151.1 - 0.7 9.5 8.1 0.52 9.9 1.6 2.5 2 0 0 2 2 2 0 PIG-P Glycos_transf_1 PF00534.15 EWM27152.1 - 1.8e-26 92.6 0.0 3.2e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EWM27152.1 - 2e-16 60.3 0.0 5.5e-16 58.9 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EWM27152.1 - 3.9e-15 56.3 0.1 1.3e-14 54.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EWM27152.1 - 5.2e-13 49.0 0.0 1.2e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EWM27152.1 - 1.6e-07 31.1 0.1 3e-07 30.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_2 PF13477.1 EWM27152.1 - 0.0099 15.7 0.1 0.015 15.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like PPR_2 PF13041.1 EWM27154.1 - 5.7e-38 128.6 0.3 5.8e-11 42.2 0.0 6.7 2 1 5 7 7 7 6 PPR repeat family PPR_3 PF13812.1 EWM27154.1 - 5.4e-32 107.3 4.5 1.3e-05 25.0 0.0 6.9 7 0 0 7 7 7 5 Pentatricopeptide repeat domain PPR PF01535.15 EWM27154.1 - 1.3e-31 106.3 5.5 1.4e-05 24.7 0.0 6.3 6 0 0 6 6 6 5 PPR repeat PPR_1 PF12854.2 EWM27154.1 - 1.2e-15 56.6 0.0 0.0004 19.8 0.0 5.5 5 0 0 5 5 5 4 PPR repeat TPR_12 PF13424.1 EWM27154.1 - 0.14 12.0 0.4 8 6.4 0.0 3.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.20 EWM27155.1 - 5.9e-65 218.9 0.0 3.8e-64 216.3 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM27155.1 - 1.1e-33 116.4 0.0 1.3e-22 80.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.17 EWM27155.1 - 0.00069 19.0 0.5 0.0018 17.6 0.3 1.7 1 0 0 1 1 1 1 RIO1 family DIRP PF06584.8 EWM27156.1 - 1.8e-17 63.1 0.7 4.2e-17 61.9 0.5 1.6 1 0 0 1 1 1 1 DIRP ASF1_hist_chap PF04729.8 EWM27157.1 - 5.2e-64 214.5 0.5 6.6e-64 214.2 0.3 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone CobT PF06213.7 EWM27157.1 - 0.53 9.3 11.3 0.77 8.8 7.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF1510 PF07423.6 EWM27157.1 - 5.8 6.2 10.2 9.2 5.5 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Nop14 PF04147.7 EWM27157.1 - 8.3 4.1 14.6 11 3.8 10.1 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1673 PF07895.6 EWM27158.1 - 3.9 6.9 5.8 12 5.3 4.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) TauD PF02668.11 EWM27159.1 - 1.5e-31 109.9 0.0 2.1e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 7TM_GPCR_Srsx PF10320.4 EWM27160.1 - 0.047 12.8 0.7 0.066 12.3 0.5 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srsx ABC2_membrane PF01061.19 EWM27161.1 - 4.4e-12 45.6 15.1 4.4e-12 45.6 10.5 1.7 2 0 0 2 2 2 1 ABC-2 type transporter DOT1 PF08123.8 EWM27163.1 - 1.1e-14 54.2 0.0 2.1e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 EWM27163.1 - 0.003 18.1 0.0 0.0059 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM27163.1 - 0.0088 16.0 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM27163.1 - 0.03 14.0 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CobT PF06213.7 EWM27163.1 - 0.058 12.5 5.7 0.094 11.8 3.9 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT AICARFT_IMPCHas PF01808.13 EWM27164.1 - 4.8e-93 311.6 0.0 6.4e-93 311.2 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EWM27164.1 - 1.5e-24 85.7 0.0 3.2e-24 84.6 0.0 1.6 1 0 0 1 1 1 1 MGS-like domain Lyase_1 PF00206.15 EWM27165.1 - 1.2e-18 67.3 0.0 2e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EWM27165.1 - 3.1e-15 55.9 0.0 9.9e-15 54.3 0.0 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Ribosomal_S9 PF00380.14 EWM27166.1 - 3.8e-37 127.2 0.1 4.3e-37 127.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 tRNA-synt_2b PF00587.20 EWM27167.1 - 7.2e-45 152.6 0.0 1.5e-44 151.6 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EWM27167.1 - 1.2e-21 76.4 0.1 5.9e-21 74.2 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain ERG4_ERG24 PF01222.12 EWM27168.1 - 4.5e-131 437.3 1.8 8.5e-120 400.1 1.1 3.0 3 0 0 3 3 3 3 Ergosterol biosynthesis ERG4/ERG24 family PDR_CDR PF06422.7 EWM27168.1 - 0.09 12.4 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 CDR ABC transporter Ras PF00071.17 EWM27169.1 - 5.5e-64 214.4 0.0 6.6e-64 214.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EWM27169.1 - 1.9e-20 73.5 0.0 4.2e-20 72.4 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EWM27169.1 - 5.9e-16 58.2 0.0 7.1e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EWM27169.1 - 4.4e-07 29.2 0.0 5.6e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EWM27169.1 - 2.5e-06 27.0 0.0 6.5e-06 25.6 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EWM27169.1 - 0.00029 20.1 0.1 0.001 18.3 0.0 1.6 1 1 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EWM27169.1 - 0.001 18.9 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase BRCA2 PF00634.13 EWM27169.1 - 0.035 13.3 1.0 5.9 6.2 0.2 2.7 2 0 0 2 2 2 0 BRCA2 repeat AAA_29 PF13555.1 EWM27169.1 - 0.036 13.6 0.0 0.087 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EWM27169.1 - 0.036 14.2 0.0 0.067 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.15 EWM27169.1 - 0.049 12.3 0.5 3.3 6.3 0.1 2.7 1 1 1 2 2 2 0 G-protein alpha subunit MCM PF00493.18 EWM27169.1 - 0.052 12.3 0.0 0.091 11.5 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family DUF258 PF03193.11 EWM27169.1 - 0.073 12.2 0.1 0.19 10.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 EWM27169.1 - 0.082 12.6 0.0 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EWM27169.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain DAGAT PF03982.8 EWM27171.1 - 2.6e-32 111.6 0.0 3.3e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Ribosomal_L9_N PF01281.14 EWM27172.1 - 5.3e-16 57.5 1.0 7.8e-16 57.0 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.9 EWM27172.1 - 0.00078 19.4 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, C-terminal domain Aminotran_3 PF00202.16 EWM27173.1 - 2.8e-44 151.3 0.1 1.5e-24 86.4 0.1 2.3 2 0 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.1 EWM27173.1 - 3.9e-36 124.5 0.0 6.6e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 EWM27173.1 - 0.079 12.3 0.2 0.26 10.6 0.1 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DNA_pol_phi PF04931.8 EWM27174.1 - 1.2e-17 62.9 0.0 1.6e-08 32.8 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase phi DAGAT PF03982.8 EWM27175.1 - 1.4e-41 142.1 0.0 1.6e-41 141.9 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase MTHFR PF02219.12 EWM27176.1 - 2.5e-91 305.7 0.0 3.8e-91 305.1 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Ssu72 PF04722.8 EWM27177.1 - 3.5e-50 170.0 0.0 4.5e-50 169.6 0.0 1.1 1 0 0 1 1 1 1 Ssu72-like protein PBP1_TM PF14812.1 EWM27177.1 - 0.032 14.5 5.6 0.064 13.5 3.9 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ferrochelatase PF00762.14 EWM27178.1 - 4.3e-112 374.1 0.0 5.2e-112 373.9 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.12 EWM27178.1 - 0.00053 20.0 0.1 0.12 12.4 0.0 2.6 2 0 0 2 2 2 2 CbiX HgmA PF04209.8 EWM27178.1 - 0.17 10.2 0.0 0.25 9.6 0.0 1.2 1 0 0 1 1 1 0 homogentisate 1,2-dioxygenase NIF PF03031.13 EWM27179.1 - 6.1e-39 133.2 0.0 9.2e-39 132.6 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase UDG PF03167.14 EWM27180.1 - 5.9e-08 32.3 0.0 1.1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily ABC_tran PF00005.22 EWM27181.1 - 1.3e-20 74.1 0.1 3.5e-20 72.7 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.1 EWM27181.1 - 3.5e-07 30.3 0.0 6.5e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 EWM27181.1 - 3.8e-05 23.8 0.0 0.022 14.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EWM27181.1 - 0.00039 21.2 0.0 0.0011 19.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EWM27181.1 - 0.00083 19.3 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EWM27181.1 - 0.00089 18.7 0.1 0.0018 17.7 0.0 1.5 2 0 0 2 2 1 1 AAA domain AAA_29 PF13555.1 EWM27181.1 - 0.0016 17.9 0.3 0.0046 16.4 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EWM27181.1 - 0.0018 17.4 0.1 0.0035 16.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 EWM27181.1 - 0.0022 18.3 0.7 0.015 15.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EWM27181.1 - 0.0024 17.1 0.1 0.062 12.5 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA PF00004.24 EWM27181.1 - 0.0029 17.8 0.0 0.015 15.4 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EWM27181.1 - 0.0034 17.5 0.0 0.0087 16.2 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 EWM27181.1 - 0.0063 16.8 0.0 0.016 15.4 0.0 1.7 2 0 0 2 2 1 1 AAA domain Rad17 PF03215.10 EWM27181.1 - 0.011 14.4 0.0 0.017 13.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_33 PF13671.1 EWM27181.1 - 0.011 15.5 0.0 0.036 13.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EWM27181.1 - 0.012 14.7 0.3 0.02 14.0 0.2 1.3 1 0 0 1 1 1 0 KaiC Arch_ATPase PF01637.13 EWM27181.1 - 0.016 14.9 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase TNFR_c6 PF00020.13 EWM27181.1 - 0.017 15.1 0.2 0.036 14.1 0.2 1.6 1 0 0 1 1 1 0 TNFR/NGFR cysteine-rich region PduV-EutP PF10662.4 EWM27181.1 - 0.03 13.8 0.0 0.26 10.7 0.0 2.3 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation Selenoprotein_S PF06936.6 EWM27181.1 - 0.033 13.7 0.3 0.063 12.8 0.2 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) SbcCD_C PF13558.1 EWM27181.1 - 0.034 14.0 0.0 0.095 12.6 0.0 1.8 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 EWM27181.1 - 0.097 12.3 0.2 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 NACHT domain MobB PF03205.9 EWM27181.1 - 0.11 12.1 0.2 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 EWM27181.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein cobW PF02492.14 EWM27181.1 - 0.14 11.5 0.4 0.29 10.5 0.3 1.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 EWM27181.1 - 0.16 12.1 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 EWM27181.1 - 0.16 11.8 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ribosomal_L1 PF00687.16 EWM27182.1 - 5.9e-44 150.0 0.0 8.2e-44 149.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF1180 PF06679.7 EWM27183.1 - 4.5 7.1 5.5 12 5.7 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) ESCRT-II PF05871.7 EWM27184.1 - 1.8e-36 125.1 0.0 2.4e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit TPR_11 PF13414.1 EWM27185.1 - 2.8e-19 68.5 12.4 8.3e-08 31.7 0.5 6.5 4 2 3 7 7 7 5 TPR repeat TPR_16 PF13432.1 EWM27185.1 - 1e-13 51.5 2.4 1.5e-05 25.4 0.0 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 EWM27185.1 - 1.4e-12 47.7 6.5 0.0014 18.9 0.2 5.4 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EWM27185.1 - 5.6e-12 44.6 15.4 0.00034 20.3 0.0 8.5 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_12 PF13424.1 EWM27185.1 - 7.3e-11 41.8 11.0 1.6e-05 24.7 0.9 5.3 4 2 1 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EWM27185.1 - 3.2e-09 36.8 13.1 1.7e-05 24.8 1.2 4.9 2 2 3 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EWM27185.1 - 1.3e-07 30.8 1.0 1.4 8.8 0.0 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EWM27185.1 - 3.9e-07 30.1 0.1 1 9.9 0.0 6.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 EWM27185.1 - 6.4e-07 29.4 0.8 0.012 16.1 0.0 5.7 4 3 3 7 7 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 EWM27185.1 - 0.00019 20.9 17.2 0.026 14.1 0.0 6.9 9 1 1 10 10 10 2 Tetratricopeptide repeat TPR_9 PF13371.1 EWM27185.1 - 0.0087 15.8 1.9 0.11 12.4 0.0 3.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 EWM27185.1 - 0.015 15.1 0.2 4.8 7.2 0.0 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 EWM27185.1 - 0.021 14.5 7.2 5.9 6.9 0.1 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat N2227 PF07942.7 EWM27186.1 - 1.3e-75 253.9 0.0 6.7e-39 133.4 0.0 2.1 2 0 0 2 2 2 2 N2227-like protein Tim17 PF02466.14 EWM27188.1 - 0.00055 19.9 0.5 0.0012 18.8 0.4 1.5 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family SLT PF01464.15 EWM27189.1 - 0.1 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Transglycosylase SLT domain Methyltransf_31 PF13847.1 EWM27190.1 - 1.7e-11 43.9 0.0 3.3e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EWM27190.1 - 2e-10 40.2 0.0 3.2e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EWM27190.1 - 2.1e-10 40.6 0.1 3.1e-09 36.8 0.0 2.7 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM27190.1 - 2.4e-09 37.7 0.1 2e-08 34.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM27190.1 - 2e-07 31.4 0.1 1.5e-06 28.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.6 EWM27190.1 - 1.2e-05 24.2 0.1 1.8e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Met_10 PF02475.11 EWM27190.1 - 4.7e-05 23.0 0.0 9.2e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein PRMT5 PF05185.11 EWM27190.1 - 6e-05 22.1 0.0 0.00012 21.1 0.0 1.4 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase MTS PF05175.9 EWM27190.1 - 0.00016 21.0 0.2 0.00028 20.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EWM27190.1 - 0.00024 21.3 0.0 0.0007 19.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM27190.1 - 0.0038 16.9 0.0 0.0071 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EWM27190.1 - 0.0045 16.1 0.0 0.0067 15.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EWM27190.1 - 0.0087 16.5 0.0 0.02 15.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EWM27190.1 - 0.081 12.3 0.1 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 Putative methyltransferase UPF0020 PF01170.13 EWM27190.1 - 0.12 11.9 0.1 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 SIR2 PF02146.12 EWM27191.1 - 8.9e-20 71.1 0.0 1.5e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 Sir2 family NUDIX PF00293.23 EWM27191.1 - 5.2e-05 22.9 0.0 9.3e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain TPP_enzyme_M PF00205.17 EWM27191.1 - 0.041 13.6 0.0 0.49 10.1 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain DUF1509 PF07420.6 EWM27191.1 - 0.19 11.0 0.2 0.28 10.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) CH PF00307.26 EWM27192.1 - 6.8e-11 42.1 0.4 1.1e-10 41.5 0.3 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain EB1 PF03271.12 EWM27192.1 - 1.9e-09 37.3 3.9 3e-09 36.7 0.8 2.3 2 0 0 2 2 2 1 EB1-like C-terminal motif Suppressor_APC PF11414.3 EWM27192.1 - 0.00024 20.8 1.5 0.00051 19.7 1.0 1.5 1 0 0 1 1 1 1 Adenomatous polyposis coli tumour suppressor protein bZIP_1 PF00170.16 EWM27192.1 - 0.079 12.9 0.4 0.19 11.7 0.3 1.6 1 0 0 1 1 1 0 bZIP transcription factor CH PF00307.26 EWM27193.1 - 6.2e-11 42.3 0.4 9.7e-11 41.6 0.3 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain EB1 PF03271.12 EWM27193.1 - 1.7e-09 37.5 3.9 2.8e-09 36.8 0.8 2.3 2 0 0 2 2 2 1 EB1-like C-terminal motif Suppressor_APC PF11414.3 EWM27193.1 - 0.00023 20.9 1.5 0.00047 19.8 1.0 1.5 1 0 0 1 1 1 1 Adenomatous polyposis coli tumour suppressor protein bZIP_1 PF00170.16 EWM27193.1 - 0.076 12.9 0.4 0.18 11.8 0.3 1.5 1 0 0 1 1 1 0 bZIP transcription factor HALZ PF02183.13 EWM27193.1 - 8 6.2 6.3 3.2 7.5 0.9 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper Aha1_N PF09229.6 EWM27195.1 - 2.4e-17 63.0 0.0 4.2e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal TPR_11 PF13414.1 EWM27195.1 - 7.7e-16 57.4 6.5 9.3e-11 41.2 0.3 2.4 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EWM27195.1 - 2.8e-13 48.8 5.3 2.5e-07 30.0 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EWM27195.1 - 2e-08 33.4 5.2 0.0025 17.6 0.1 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EWM27195.1 - 1.2e-05 25.4 1.3 0.043 14.4 0.0 3.4 2 1 2 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EWM27195.1 - 2.5e-05 24.1 1.9 0.07 13.3 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EWM27195.1 - 0.00028 20.7 2.1 0.15 12.0 1.7 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EWM27195.1 - 0.00032 20.2 2.5 0.044 13.5 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EWM27195.1 - 0.0012 19.4 11.3 0.0051 17.4 3.0 2.9 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EWM27195.1 - 0.0096 16.2 2.2 2.7 8.3 0.4 2.9 2 1 2 4 4 4 2 Tetratricopeptide repeat TOM20_plant PF06552.7 EWM27195.1 - 0.034 13.7 1.6 0.14 11.7 0.8 2.1 1 1 1 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 Apc3 PF12895.2 EWM27195.1 - 0.059 13.5 2.2 1.1 9.4 1.5 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 NUDIX PF00293.23 EWM27196.1 - 4.1e-15 55.5 0.1 5.4e-15 55.2 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain Syntaxin-18_N PF10496.4 EWM27197.1 - 1.7e-07 30.9 0.1 2.7e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 SNARE-complex protein Syntaxin-18 N-terminus DUF3510 PF12022.3 EWM27197.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) NAD_kinase PF01513.16 EWM27198.1 - 9.8e-14 50.7 0.0 1.8e-08 33.5 0.0 2.2 2 0 0 2 2 2 2 ATP-NAD kinase DAGK_cat PF00781.19 EWM27198.1 - 0.0051 16.2 0.0 0.0091 15.4 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF647 PF04884.9 EWM27199.1 - 1.3e-82 276.8 2.0 1.7e-82 276.3 1.4 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DUF1336 PF07059.7 EWM27200.1 - 1.2e-57 194.8 0.0 1.8e-57 194.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) START PF01852.14 EWM27200.1 - 1.4e-14 53.9 0.0 2.8e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 START domain PH PF00169.24 EWM27200.1 - 8e-07 29.2 0.0 0.00024 21.2 0.0 2.4 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 EWM27200.1 - 0.00029 21.0 0.6 0.0011 19.2 0.1 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 EWM27200.1 - 0.032 14.2 0.2 0.23 11.5 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain G10 PF01125.12 EWM27201.1 - 1.3e-50 170.7 1.0 1.3e-50 170.7 0.7 1.6 2 0 0 2 2 2 1 G10 protein Nucleoplasmin PF03066.10 EWM27201.1 - 0.034 13.6 4.6 0.049 13.1 3.2 1.2 1 0 0 1 1 1 0 Nucleoplasmin Ribosomal_60s PF00428.14 EWM27201.1 - 0.039 14.3 12.2 0.072 13.5 8.4 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein S-antigen PF05756.6 EWM27201.1 - 0.16 11.9 4.3 0.34 10.9 3.0 1.5 1 0 0 1 1 1 0 S-antigen protein VID27 PF08553.5 EWM27201.1 - 2.1 6.4 6.4 2.8 6.0 4.4 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Myc_N PF01056.13 EWM27201.1 - 3.7 6.6 6.0 5.3 6.1 4.2 1.2 1 0 0 1 1 1 0 Myc amino-terminal region XPG_I PF00867.13 EWM27203.1 - 2.2e-16 59.6 0.0 5.1e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EWM27203.1 - 7.7e-14 51.7 0.0 1.5e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain Aminotran_1_2 PF00155.16 EWM27204.1 - 2e-83 280.3 0.0 2.3e-83 280.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Thioredoxin_8 PF13905.1 EWM27205.1 - 1.4e-46 156.4 0.1 2.9e-30 104.2 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.16 EWM27205.1 - 1.7e-13 50.3 0.8 1.9e-07 30.8 0.0 3.4 2 1 1 3 3 3 2 AhpC/TSA family Thioredoxin_2 PF13098.1 EWM27205.1 - 1.9e-11 44.1 0.4 1.5e-08 34.8 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.15 EWM27205.1 - 1e-09 37.9 0.6 8.7e-07 28.5 0.3 3.2 2 1 1 3 3 3 2 Thioredoxin Redoxin PF08534.5 EWM27205.1 - 2.3e-05 23.9 0.0 0.00015 21.2 0.0 2.2 2 0 0 2 2 2 1 Redoxin SCO1-SenC PF02630.9 EWM27205.1 - 2.7e-05 23.8 0.0 0.066 12.8 0.0 2.6 2 0 0 2 2 2 2 SCO1/SenC Thioredoxin_7 PF13899.1 EWM27205.1 - 4.8e-05 23.3 0.0 0.00047 20.1 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EWM27205.1 - 0.025 14.1 0.2 0.5 9.9 0.0 3.0 4 0 0 4 4 4 0 Thioredoxin Peptidase_C3 PF00548.15 EWM27205.1 - 0.084 12.6 0.1 0.34 10.7 0.0 1.9 2 0 0 2 2 2 0 3C cysteine protease (picornain 3C) KaiC PF06745.8 EWM27205.1 - 0.12 11.4 0.0 0.27 10.3 0.0 1.5 1 0 0 1 1 1 0 KaiC CK_II_beta PF01214.13 EWM27206.1 - 1.6e-47 161.4 0.0 4.9e-30 104.3 0.0 2.2 2 0 0 2 2 2 2 Casein kinase II regulatory subunit Mito_carr PF00153.22 EWM27207.1 - 3.9e-37 125.8 8.2 1.2e-20 72.9 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Methyltransf_26 PF13659.1 EWM27208.1 - 1e-06 28.7 1.2 5.4e-06 26.4 0.1 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM27208.1 - 8.5e-06 26.3 0.0 2.3e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EWM27208.1 - 7.4e-05 22.0 0.0 0.00012 21.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.7 EWM27208.1 - 0.00016 22.1 0.1 0.0018 18.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain TPR_2 PF07719.12 EWM27208.1 - 0.00075 19.2 0.2 0.0038 17.0 0.1 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 EWM27208.1 - 0.0034 16.9 1.9 0.0054 16.3 0.2 2.1 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EWM27208.1 - 0.0056 16.2 0.0 0.014 14.9 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat Methyltransf_11 PF08241.7 EWM27208.1 - 0.016 15.7 0.0 0.044 14.2 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EWM27208.1 - 0.016 14.5 0.0 0.035 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.1 EWM27208.1 - 0.017 14.8 0.0 0.042 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Imm_superinfect PF14373.1 EWM27208.1 - 0.043 13.4 0.1 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 Superinfection immunity protein Apc3 PF12895.2 EWM27208.1 - 0.12 12.5 0.5 0.43 10.7 0.4 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EWM27208.1 - 0.21 11.5 3.6 0.27 11.2 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EWM27208.1 - 1.2 9.9 7.4 0.25 12.0 0.6 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EWM27208.1 - 2.8 8.7 9.2 8.6 7.1 1.3 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF663 PF04950.7 EWM27209.1 - 6e-90 301.2 0.0 7e-75 251.7 0.0 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF663) Dynamin_N PF00350.18 EWM27210.1 - 1.1e-09 38.2 0.0 2.2e-07 30.8 0.0 2.9 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EWM27210.1 - 1.1e-05 25.3 0.0 2.4e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EWM27210.1 - 0.013 15.9 0.0 0.29 11.6 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein Lysine_decarbox PF03641.9 EWM27210.1 - 0.18 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Possible lysine decarboxylase ERO1 PF04137.10 EWM27211.1 - 9.2e-108 360.4 0.0 1.9e-107 359.3 0.0 1.5 1 1 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Fer4_18 PF13746.1 EWM27211.1 - 0.017 15.5 0.2 0.058 13.8 0.1 1.9 1 0 0 1 1 1 0 4Fe-4S dicluster domain Glycos_transf_1 PF00534.15 EWM27212.1 - 4.2e-09 36.0 0.0 7.9e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EWM27212.1 - 1.7e-08 34.6 0.0 3.5e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EWM27212.1 - 0.0013 18.9 1.4 0.019 15.2 0.0 2.9 3 0 0 3 3 3 1 Glycosyl transferases group 1 WD40 PF00400.27 EWM27213.1 - 8.6e-16 57.1 11.7 1.1e-05 25.0 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat PQQ_3 PF13570.1 EWM27213.1 - 0.043 14.1 0.9 60 4.1 0.0 4.2 5 0 0 5 5 5 0 PQQ-like domain PQQ_2 PF13360.1 EWM27213.1 - 0.063 12.7 1.2 0.19 11.1 0.1 2.3 2 1 0 2 2 2 0 PQQ-like domain RNase_PH PF01138.16 EWM27214.1 - 5.9e-34 117.2 0.1 1.3e-20 74.0 0.0 2.4 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EWM27214.1 - 9.3e-23 79.9 0.6 1.1e-14 54.0 0.0 3.2 2 1 0 2 2 2 2 3' exoribonuclease family, domain 2 S1 PF00575.18 EWM27214.1 - 6.1e-13 48.6 0.5 2.7e-12 46.5 0.1 2.3 2 0 0 2 2 2 1 S1 RNA binding domain IMS PF00817.15 EWM27215.1 - 8.8e-44 148.9 0.1 1.6e-43 148.0 0.1 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EWM27215.1 - 4e-09 36.4 0.1 8.8e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 EWM27215.1 - 0.002 18.0 0.0 0.005 16.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4414) IMS_HHH PF11798.3 EWM27215.1 - 0.1 12.7 0.2 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 IMS family HHH motif RrnaAD PF00398.15 EWM27216.1 - 4.4e-40 137.3 0.0 8.7e-40 136.3 0.0 1.5 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EWM27216.1 - 5.2e-08 32.9 0.1 9.6e-08 32.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM27216.1 - 5.9e-05 23.6 0.0 0.00014 22.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM27216.1 - 6.9e-05 22.6 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EWM27216.1 - 0.00018 20.9 0.0 0.00028 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EWM27216.1 - 0.022 15.0 0.0 0.045 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain zf-RING_2 PF13639.1 EWM27218.1 - 3.4e-09 36.3 4.2 3.4e-09 36.3 2.9 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EWM27218.1 - 2.1e-08 33.7 1.2 2.1e-08 33.7 0.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EWM27218.1 - 1.7e-06 27.9 4.5 1.7e-06 27.9 3.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EWM27218.1 - 0.00013 21.5 3.7 0.00013 21.5 2.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EWM27218.1 - 0.0002 21.4 1.0 0.00042 20.3 0.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EWM27218.1 - 0.00029 20.4 3.0 0.00029 20.4 2.1 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EWM27218.1 - 0.099 12.3 0.4 0.099 12.3 0.3 2.5 2 0 0 2 2 2 0 RING-type zinc-finger ABC2_membrane PF01061.19 EWM27219.1 - 9.9e-66 220.8 55.6 1.4e-34 119.0 14.5 2.6 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.22 EWM27219.1 - 8.5e-34 116.7 0.0 7.1e-18 65.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 EWM27219.1 - 2.4e-12 46.5 42.1 5.1e-08 32.3 9.2 2.5 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 EWM27219.1 - 1.3e-08 35.1 0.0 0.46 10.4 0.0 4.3 4 0 0 4 4 4 2 AAA domain PDR_assoc PF08370.6 EWM27219.1 - 1.5e-08 34.0 1.5 5.7e-08 32.1 1.0 2.0 1 0 0 1 1 1 1 Plant PDR ABC transporter associated AAA_25 PF13481.1 EWM27219.1 - 2.7e-07 30.2 3.1 0.0057 16.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.1 EWM27219.1 - 9.3e-05 22.4 2.4 0.3 11.0 0.1 3.1 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 EWM27219.1 - 0.00018 20.9 1.3 0.037 13.5 0.3 3.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain Miro PF08477.8 EWM27219.1 - 0.00023 21.6 0.8 0.42 11.1 0.1 2.5 2 0 0 2 2 2 2 Miro-like protein PduV-EutP PF10662.4 EWM27219.1 - 0.00048 19.6 1.6 0.67 9.4 0.1 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 EWM27219.1 - 0.00074 18.7 0.4 0.0082 15.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EWM27219.1 - 0.0015 18.6 0.4 0.74 9.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EWM27219.1 - 0.0031 17.5 5.6 0.42 10.5 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA PF00004.24 EWM27219.1 - 0.0034 17.6 1.5 0.38 10.9 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EWM27219.1 - 0.0039 16.9 0.1 0.17 11.5 0.0 2.6 2 0 0 2 2 2 1 Archaeal ATPase FeoB_N PF02421.13 EWM27219.1 - 0.023 13.9 0.1 2.8 7.2 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_17 PF13207.1 EWM27219.1 - 0.032 15.0 2.7 6.9 7.5 0.0 3.1 3 0 0 3 3 2 0 AAA domain T2SE PF00437.15 EWM27219.1 - 0.049 12.5 0.2 3.7 6.3 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.1 EWM27219.1 - 0.052 13.8 0.3 7.2 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 EWM27219.1 - 0.06 12.3 0.0 11 4.8 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain Dynamin_N PF00350.18 EWM27219.1 - 0.081 12.7 0.6 7.4 6.3 0.0 2.4 2 0 0 2 2 2 0 Dynamin family MMR_HSR1 PF01926.18 EWM27219.1 - 0.087 12.7 0.9 15 5.5 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.1 EWM27219.1 - 0.15 11.6 1.2 14 5.1 0.2 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EWM27219.1 - 0.17 11.3 1.8 0.16 11.3 0.1 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 EWM27219.1 - 0.32 10.4 1.0 26 4.2 0.1 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_18 PF13238.1 EWM27219.1 - 0.85 9.9 2.5 7.2 6.9 0.1 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EWM27219.1 - 0.88 8.6 4.5 8 5.5 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin AAA_24 PF13479.1 EWM27219.1 - 1.2 8.6 2.5 7.1 6.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EWM27219.1 - 6.9 6.5 13.0 0.57 9.9 0.0 3.5 4 0 0 4 4 3 0 Part of AAA domain TMEM206 PF15122.1 EWM27222.1 - 0.0076 15.2 0.2 0.0078 15.1 0.1 1.1 1 0 0 1 1 1 1 TMEM206 protein family FCH PF00611.18 EWM27222.1 - 0.087 13.0 0.0 0.1 12.8 0.0 1.1 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain Arm PF00514.18 EWM27223.1 - 0.0023 17.6 1.1 0.18 11.6 0.0 2.7 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EWM27223.1 - 0.0044 17.2 0.2 1.1 9.6 0.1 2.3 2 0 0 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 EWM27223.1 - 0.064 13.7 2.9 14 6.2 0.0 3.5 3 1 0 3 3 3 0 HEAT-like repeat Kinesin PF00225.18 EWM27224.1 - 1.6e-99 332.8 0.0 2.3e-99 332.2 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain DUF2064 PF09837.4 EWM27224.1 - 0.059 12.9 0.0 0.18 11.4 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) Dus PF01207.12 EWM27226.1 - 3.9e-57 193.4 0.0 5.6e-57 192.9 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) ThiG PF05690.9 EWM27226.1 - 0.068 12.2 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG PEP_mutase PF13714.1 EWM27226.1 - 0.069 12.3 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase DUF849 PF05853.7 EWM27226.1 - 0.14 11.0 0.1 0.22 10.3 0.1 1.3 1 0 0 1 1 1 0 Prokaryotic protein of unknown function (DUF849) Tub PF01167.13 EWM27227.1 - 1.7e-23 82.8 0.0 3e-23 82.0 0.0 1.5 1 1 0 1 1 1 1 Tub family DUF3527 PF12043.3 EWM27227.1 - 0.001 18.6 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3527) AAA_27 PF13514.1 EWM27227.1 - 0.13 9.9 0.8 0.17 9.5 0.6 1.1 1 0 0 1 1 1 0 AAA domain SelR PF01641.13 EWM27229.1 - 1.8e-39 134.2 0.1 2.6e-39 133.7 0.1 1.2 1 0 0 1 1 1 1 SelR domain SET PF00856.23 EWM27230.1 - 7.9e-24 84.7 0.3 4e-23 82.4 0.0 2.4 2 0 0 2 2 2 1 SET domain PHD PF00628.24 EWM27230.1 - 2.3e-06 27.2 12.5 2.3e-06 27.2 8.7 2.2 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 EWM27230.1 - 5.3e-06 25.6 4.0 1.5e-05 24.2 2.8 1.8 1 0 0 1 1 1 1 PHD-finger zf-RING_2 PF13639.1 EWM27231.1 - 9.9e-11 41.2 3.6 1.7e-10 40.5 2.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EWM27231.1 - 2.6e-06 27.4 0.6 5.3e-06 26.4 0.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EWM27231.1 - 7.2e-06 25.5 2.2 1.2e-05 24.8 1.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EWM27231.1 - 2.4e-05 23.9 4.7 3.9e-05 23.2 3.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EWM27231.1 - 3e-05 23.9 3.7 6.9e-05 22.7 2.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EWM27231.1 - 0.0001 21.8 5.9 0.00023 20.7 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EWM27231.1 - 0.0074 15.9 3.2 0.015 14.9 2.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 EWM27231.1 - 0.012 15.1 1.0 0.021 14.3 0.7 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Baculo_RING PF05883.6 EWM27231.1 - 0.054 13.3 1.2 0.097 12.5 0.8 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-Apc11 PF12861.2 EWM27231.1 - 0.064 13.1 1.9 0.12 12.1 1.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger XRN_N PF03159.13 EWM27232.1 - 2.3e-99 331.6 0.0 4.2e-99 330.7 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus HALZ PF02183.13 EWM27233.1 - 0.018 14.7 0.7 0.044 13.4 0.1 1.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper Acetyltransf_11 PF13720.1 EWM27233.1 - 0.09 13.0 0.2 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 bZIP_1 PF00170.16 EWM27233.1 - 0.11 12.4 1.0 0.2 11.6 0.7 1.4 1 0 0 1 1 1 0 bZIP transcription factor DUF972 PF06156.8 EWM27233.1 - 0.14 12.4 0.9 0.24 11.7 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) bZIP_2 PF07716.10 EWM27234.1 - 2.3e-11 43.3 28.8 1.7e-07 30.9 7.7 2.6 2 0 0 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.16 EWM27234.1 - 6.5e-09 35.6 21.6 6.7e-05 22.7 4.9 2.6 2 0 0 2 2 2 2 bZIP transcription factor SR-25 PF10500.4 EWM27234.1 - 0.0032 16.9 6.9 0.0032 16.9 4.8 3.3 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein bZIP_Maf PF03131.12 EWM27234.1 - 0.42 10.9 21.3 0.36 11.1 2.7 2.7 2 0 0 2 2 2 0 bZIP Maf transcription factor FimP PF09766.4 EWM27234.1 - 7.2 5.5 10.5 0.095 11.7 0.5 2.4 3 0 0 3 3 3 0 Fms-interacting protein Cellulose_synt PF03552.9 EWM27236.1 - 0.014 13.7 1.5 0.18 10.0 0.1 2.1 1 1 1 2 2 2 0 Cellulose synthase IGPD PF00475.13 EWM27237.1 - 1e-58 197.2 2.6 2e-58 196.3 1.8 1.5 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase HAD_2 PF13419.1 EWM27237.1 - 2.1e-17 63.9 0.0 4.1e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EWM27237.1 - 1.8e-10 41.5 0.2 8.6e-08 32.8 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EWM27237.1 - 1e-09 37.9 0.1 3.9e-09 36.0 0.0 2.0 1 1 0 1 1 1 1 HAD-hyrolase-like ATP-synt_DE_N PF02823.11 EWM27238.1 - 6.7e-17 61.0 0.2 1.2e-16 60.2 0.1 1.4 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Pyridoxal_deC PF00282.14 EWM27238.1 - 0.052 11.9 0.0 0.068 11.6 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain PDGLE PF13190.1 EWM27238.1 - 0.056 13.1 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 PDGLE domain zf-TAZ PF02135.11 EWM27239.1 - 9.9e-08 31.8 11.8 9.9e-08 31.8 8.2 1.9 2 0 0 2 2 2 1 TAZ zinc finger Sdh5 PF03937.11 EWM27240.1 - 5e-19 67.7 0.0 8e-19 67.1 0.0 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase CHORD PF04968.7 EWM27241.1 - 1.5e-49 166.0 19.4 2.4e-26 91.7 5.9 2.3 2 0 0 2 2 2 2 CHORD TFR_dimer PF04253.10 EWM27242.1 - 5.3e-23 80.9 0.0 8.5e-23 80.2 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EWM27242.1 - 4.7e-16 59.0 0.0 9.4e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EWM27242.1 - 8.3e-11 41.4 0.0 3.4e-10 39.5 0.0 2.1 2 0 0 2 2 2 1 PA domain SBP_bac_5 PF00496.17 EWM27242.1 - 0.00018 20.4 0.0 0.00028 19.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle Peptidase_M20 PF01546.23 EWM27242.1 - 0.081 12.4 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 SAC3_GANP PF03399.11 EWM27243.1 - 4.8e-12 45.8 0.0 8.4e-12 45.0 0.0 1.4 1 1 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DUF2600 PF10776.4 EWM27243.1 - 0.044 12.6 0.0 0.082 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2600) PQQ_2 PF13360.1 EWM27244.1 - 0.0012 18.4 0.0 0.0044 16.5 0.0 1.8 2 0 0 2 2 2 1 PQQ-like domain SdiA-regulated PF06977.6 EWM27244.1 - 0.13 11.1 0.0 5.9 5.7 0.0 2.8 3 0 0 3 3 3 0 SdiA-regulated DUF2929 PF11151.3 EWM27245.1 - 0.061 13.4 0.0 0.086 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2929) GSH_synth_ATP PF03917.12 EWM27247.1 - 3e-91 305.7 0.0 4.7e-54 183.3 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EWM27247.1 - 9.3e-33 112.4 0.0 1.5e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic glutathione synthase FA_desaturase PF00487.19 EWM27249.1 - 3.3e-16 59.5 23.5 3.3e-16 59.5 16.3 2.0 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 EWM27249.1 - 1.8e-10 40.4 0.4 4.4e-10 39.2 0.1 1.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Pkinase PF00069.20 EWM27250.1 - 2.4e-31 108.8 0.0 3.2e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM27250.1 - 4.9e-20 71.6 0.0 2.7e-19 69.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EWM27250.1 - 6.5e-05 22.7 0.0 0.0031 17.2 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EWM27250.1 - 0.082 11.8 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Act-Frag_cataly PF09192.5 EWM27250.1 - 0.19 10.6 0.0 0.25 10.2 0.0 1.1 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic Adeno_PX PF05829.7 EWM27250.1 - 1.9 8.0 5.8 14 5.2 1.9 2.5 2 0 0 2 2 2 0 Adenovirus late L2 mu core protein (Protein X) PGP_phosphatase PF09419.5 EWM27251.1 - 8.7e-46 155.3 0.0 1.2e-45 154.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 EWM27251.1 - 0.0098 15.5 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like DUF1772 PF08592.6 EWM27252.1 - 2.1e-15 56.6 2.6 1e-08 34.9 0.1 2.8 2 1 0 2 2 2 2 Domain of unknown function (DUF1772) Nitro_FeMo-Co PF02579.12 EWM27253.1 - 0.034 14.2 0.0 0.069 13.2 0.0 1.5 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor PKI PF02827.11 EWM27253.1 - 0.064 13.3 0.3 0.16 12.1 0.2 1.7 1 1 0 1 1 1 0 cAMP-dependent protein kinase inhibitor Nnf1 PF03980.9 EWM27253.1 - 0.086 12.8 1.1 0.26 11.2 0.1 2.1 2 0 0 2 2 2 0 Nnf1 IpaD PF06511.6 EWM27253.1 - 0.15 11.0 1.1 0.19 10.6 0.4 1.4 1 1 0 1 1 1 0 Invasion plasmid antigen IpaD Med5 PF08689.5 EWM27253.1 - 0.54 7.8 3.5 0.61 7.6 2.4 1.0 1 0 0 1 1 1 0 Mediator complex subunit Med5 DnaJ PF00226.26 EWM27254.1 - 4e-17 61.6 0.0 7.1e-17 60.9 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain NuA4 PF09340.5 EWM27255.1 - 0.00022 20.7 0.2 0.00059 19.4 0.1 1.7 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 CDC45 PF02724.9 EWM27255.1 - 0.00034 18.7 28.0 0.00042 18.4 19.4 1.2 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.7 EWM27255.1 - 0.00066 17.7 43.8 0.00079 17.4 30.3 1.1 1 0 0 1 1 1 1 Nop14-like family CENP-T PF15511.1 EWM27255.1 - 0.0024 17.1 32.5 0.003 16.8 22.5 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Pilt PF15453.1 EWM27255.1 - 0.069 12.8 23.6 0.085 12.5 16.3 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Ycf1 PF05758.7 EWM27255.1 - 0.23 9.1 21.8 0.25 8.9 15.1 1.1 1 0 0 1 1 1 0 Ycf1 Mpp10 PF04006.7 EWM27255.1 - 0.26 9.6 46.0 0.38 9.0 31.9 1.3 1 0 0 1 1 1 0 Mpp10 protein CT47 PF15623.1 EWM27255.1 - 0.45 10.2 44.8 0.58 9.8 31.0 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 Daxx PF03344.10 EWM27255.1 - 2 6.8 59.2 1.3 7.3 22.2 2.0 1 1 1 2 2 2 0 Daxx Family SAPS PF04499.10 EWM27255.1 - 2 6.9 20.5 2.5 6.6 14.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein eIF-3c_N PF05470.7 EWM27255.1 - 2.2 6.2 22.2 2.7 5.9 15.4 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PLRV_ORF5 PF01690.12 EWM27255.1 - 2.9 6.9 21.2 3.3 6.7 14.7 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Neur_chan_memb PF02932.11 EWM27255.1 - 5.2 6.8 9.5 6.5 6.5 6.6 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.2 EWM27255.1 - 9.9 3.6 19.6 12 3.3 13.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PAP2 PF01569.16 EWM27256.1 - 1.1e-16 60.6 6.7 2.1e-16 59.7 4.6 1.4 1 0 0 1 1 1 1 PAP2 superfamily YtpI PF14007.1 EWM27256.1 - 0.024 14.5 0.1 9.6 6.2 0.0 2.6 2 0 0 2 2 2 0 YtpI-like protein MerC PF03203.9 EWM27256.1 - 0.089 13.1 2.9 0.31 11.4 0.1 2.6 2 1 0 2 2 2 0 MerC mercury resistance protein Epimerase PF01370.16 EWM27257.1 - 3.6e-26 92.0 0.0 7.4e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EWM27257.1 - 3e-05 23.0 0.0 0.0089 14.9 0.0 2.3 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein UDPG_MGDP_dh_N PF03721.9 EWM27257.1 - 0.0016 17.8 0.0 0.0037 16.6 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain KR PF08659.5 EWM27257.1 - 0.0055 16.3 0.0 0.0093 15.6 0.0 1.3 1 0 0 1 1 1 1 KR domain AlaDh_PNT_C PF01262.16 EWM27257.1 - 0.021 14.4 0.0 0.068 12.7 0.0 2.0 2 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3Beta_HSD PF01073.14 EWM27257.1 - 0.076 11.7 0.1 0.14 10.7 0.1 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family WW PF00397.21 EWM27258.1 - 0.00071 19.3 0.0 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 WW domain VWA PF00092.23 EWM27258.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain Brix PF04427.13 EWM27259.1 - 1.8e-44 151.7 0.0 2.2e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 Brix domain DUF1478 PF07349.6 EWM27259.1 - 0.11 11.8 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1478) UQ_con PF00179.21 EWM27260.1 - 2.7e-16 59.2 0.0 4.1e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DEAD PF00270.24 EWM27261.1 - 8.8e-45 152.2 0.0 8.3e-44 149.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EWM27261.1 - 1.2e-27 95.6 0.1 3.5e-27 94.0 0.1 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EWM27261.1 - 3.5e-05 23.7 0.0 0.0008 19.2 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EWM27261.1 - 0.047 13.6 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain DUF1253 PF06862.7 EWM27261.1 - 0.14 10.5 0.0 1.2 7.4 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1253) eIF-4B PF06273.6 EWM27261.1 - 0.95 8.1 5.3 1.9 7.1 3.7 1.4 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B YopX PF09643.5 EWM27262.1 - 0.046 13.6 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 YopX protein Not1 PF04054.10 EWM27263.1 - 3.4e-133 444.1 0.4 3.4e-133 444.1 0.3 3.8 3 1 0 3 3 3 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EWM27263.1 - 7.5e-54 181.4 0.4 7.5e-54 181.4 0.3 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3819) MGC-24 PF05283.6 EWM27264.1 - 0.094 12.4 0.8 0.72 9.6 0.7 2.0 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) HEAT_2 PF13646.1 EWM27265.1 - 2.6e-18 66.0 9.2 5.6e-05 23.3 0.0 7.4 4 2 1 7 7 7 5 HEAT repeats HEAT PF02985.17 EWM27265.1 - 3.8e-18 63.8 10.4 0.0012 18.7 0.0 9.9 10 0 0 10 10 10 4 HEAT repeat HEAT_EZ PF13513.1 EWM27265.1 - 7.1e-16 58.1 9.9 8e-09 35.7 0.0 8.1 7 2 3 10 10 10 2 HEAT-like repeat IBN_N PF03810.14 EWM27265.1 - 1.1e-10 41.2 0.3 2.1e-09 37.1 0.3 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 EWM27265.1 - 7.1e-05 23.1 0.8 29 5.1 0.0 5.7 5 1 1 6 6 6 0 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EWM27265.1 - 0.00024 20.5 0.1 0.52 9.6 0.1 4.1 4 1 0 4 4 4 1 CLASP N terminal Adaptin_N PF01602.15 EWM27265.1 - 0.00066 18.1 1.1 0.025 12.9 0.0 3.1 2 1 1 3 3 3 1 Adaptin N terminal region Cnd3 PF12719.2 EWM27265.1 - 0.00067 18.7 1.3 0.62 9.0 0.0 4.4 4 1 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain Arm PF00514.18 EWM27265.1 - 0.0075 16.0 12.1 0.69 9.8 0.0 7.1 8 0 0 8 8 8 1 Armadillo/beta-catenin-like repeat IFRD PF05004.8 EWM27265.1 - 0.022 13.8 0.2 0.25 10.3 0.0 2.6 1 1 1 2 2 2 0 Interferon-related developmental regulator (IFRD) Proteasom_PSMB PF10508.4 EWM27265.1 - 0.067 11.4 0.0 7.7 4.6 0.0 2.9 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit Synaptobrevin PF00957.16 EWM27266.1 - 4.4e-21 74.2 4.7 4.4e-21 74.2 3.3 1.6 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.1 EWM27266.1 - 2.3e-06 27.0 0.0 4.1e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF805 PF05656.9 EWM27266.1 - 0.013 15.3 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF805) DUF3665 PF12427.3 EWM27267.1 - 0.11 11.8 1.6 0.4 10.0 1.1 2.0 1 0 0 1 1 1 0 Branched-chain amino acid aminotransferase Memo PF01875.12 EWM27269.1 - 1.4e-79 266.8 0.0 1.6e-79 266.6 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein DIE2_ALG10 PF04922.7 EWM27270.1 - 0.022 13.8 0.0 0.022 13.7 0.0 1.0 1 0 0 1 1 1 0 DIE2/ALG10 family TPR_11 PF13414.1 EWM27271.1 - 2.7e-08 33.3 0.0 6.1e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 TPR repeat TPR_16 PF13432.1 EWM27271.1 - 1.7e-05 25.3 0.0 5.1e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 EWM27271.1 - 0.00072 19.2 0.0 0.15 12.0 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EWM27271.1 - 0.0083 16.2 0.6 0.063 13.4 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EWM27271.1 - 0.011 16.0 0.0 0.027 14.8 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 EWM27271.1 - 0.03 14.2 0.1 0.094 12.6 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EWM27271.1 - 0.061 12.9 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EWM27271.1 - 0.096 12.8 0.1 0.29 11.3 0.0 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 FGE-sulfatase PF03781.11 EWM27272.1 - 1.9e-71 240.5 8.2 2.3e-71 240.2 5.7 1.1 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Actin PF00022.14 EWM27273.1 - 8.3e-98 327.3 0.0 9.5e-98 327.1 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EWM27273.1 - 9e-05 21.2 0.0 0.0025 16.4 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein LMBR1 PF04791.11 EWM27274.1 - 6.5e-38 130.5 29.9 2.4e-29 102.2 1.5 2.0 2 0 0 2 2 2 2 LMBR1-like membrane protein SAP PF02037.22 EWM27275.1 - 5.4e-06 25.7 0.1 1.3e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 SAP domain Cwf_Cwc_15 PF04889.7 EWM27275.1 - 0.014 15.1 5.9 0.013 15.1 3.6 1.4 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FAM92 PF06730.6 EWM27275.1 - 0.096 12.0 0.1 0.15 11.3 0.1 1.2 1 0 0 1 1 1 0 FAM92 protein DUF572 PF04502.8 EWM27275.1 - 4.8 6.3 15.5 12 5.0 10.7 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF572) MRP-S33 PF08293.6 EWM27276.1 - 4.5e-08 32.9 0.1 8.8e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 DcpS_C PF11969.3 EWM27277.1 - 4e-23 81.8 0.1 6.5e-23 81.1 0.1 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS_C PF11969.3 EWM27278.1 - 8e-12 45.4 0.0 1.5e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Glyco_transf_90 PF05686.7 EWM27280.1 - 2.2e-28 99.0 0.0 3.1e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 TPR_MLP1_2 PF07926.7 EWM27281.1 - 3e-10 39.9 21.4 3e-10 39.9 14.9 14.3 6 5 6 12 12 12 3 TPR/MLP1/MLP2-like protein AAA PF00004.24 EWM27282.1 - 6.2e-17 62.0 0.0 1.1e-16 61.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EWM27282.1 - 2.8e-15 56.3 0.0 1.3e-14 54.1 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EWM27282.1 - 3.1e-07 29.4 0.0 4.4e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 EWM27282.1 - 9.7e-07 28.9 0.0 0.00029 20.8 0.0 2.9 1 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EWM27282.1 - 2.7e-06 27.5 0.0 5.8e-05 23.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EWM27282.1 - 7.4e-06 25.1 0.0 1.5e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EWM27282.1 - 9.6e-06 25.2 0.1 2e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EWM27282.1 - 3.5e-05 23.6 0.0 6.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EWM27282.1 - 0.00011 21.8 0.0 0.00022 20.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EWM27282.1 - 0.0005 19.9 0.0 0.0013 18.5 0.0 1.6 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit Mg_chelatase PF01078.16 EWM27282.1 - 0.00063 18.9 0.0 0.028 13.5 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 EWM27282.1 - 0.0012 18.4 0.0 0.0023 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EWM27282.1 - 0.0019 17.9 0.0 0.0081 15.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 EWM27282.1 - 0.0051 16.3 0.0 0.01 15.3 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain Arch_ATPase PF01637.13 EWM27282.1 - 0.0062 16.2 0.0 0.015 15.0 0.0 1.5 1 1 1 2 2 2 1 Archaeal ATPase AAA_24 PF13479.1 EWM27282.1 - 0.0085 15.6 0.2 0.014 14.9 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EWM27282.1 - 0.01 15.4 0.0 0.028 14.0 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 EWM27282.1 - 0.011 16.0 0.0 0.014 15.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EWM27282.1 - 0.012 14.5 0.0 0.028 13.3 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.8 EWM27282.1 - 0.013 14.4 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.1 EWM27282.1 - 0.021 14.7 0.0 0.055 13.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 EWM27282.1 - 0.023 13.9 0.3 2 7.6 0.0 2.6 2 1 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.1 EWM27282.1 - 0.024 14.0 0.2 0.081 12.3 0.1 2.0 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EWM27282.1 - 0.054 14.3 0.0 0.1 13.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain DEAD PF00270.24 EWM27282.1 - 0.082 12.3 0.1 1.8 8.0 0.0 2.1 1 1 0 2 2 2 0 DEAD/DEAH box helicase ArgK PF03308.11 EWM27282.1 - 0.11 11.2 0.1 1.4 7.6 0.0 2.1 1 1 1 2 2 2 0 ArgK protein Sigma54_activat PF00158.21 EWM27282.1 - 0.14 11.6 0.0 13 5.2 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain C2 PF00168.25 EWM27283.1 - 1.6e-05 24.6 0.0 3.8e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 C2 domain HTH_Tnp_Tc5 PF03221.11 EWM27285.1 - 0.03 14.1 0.1 2.2 8.1 0.0 2.8 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain ABC_tran PF00005.22 EWM27286.1 - 1.6e-49 167.6 0.0 1.3e-24 87.0 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EWM27286.1 - 2.2e-24 86.9 0.1 4.7e-07 30.0 0.0 4.2 3 1 1 4 4 4 4 AAA domain ABC_tran_2 PF12848.2 EWM27286.1 - 9.6e-12 44.5 4.1 2.2e-11 43.4 2.1 2.0 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 EWM27286.1 - 3.4e-07 29.7 3.1 0.78 8.9 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain Miro PF08477.8 EWM27286.1 - 5.6e-07 30.0 0.0 0.06 13.8 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 EWM27286.1 - 1.8e-06 27.3 0.6 0.02 14.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.1 EWM27286.1 - 3.7e-06 26.7 0.5 0.2 11.6 0.0 3.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 EWM27286.1 - 2.6e-05 23.7 5.9 0.0024 17.2 0.1 4.2 5 1 0 5 5 5 1 AAA domain MMR_HSR1 PF01926.18 EWM27286.1 - 0.00027 20.8 0.0 0.19 11.6 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.1 EWM27286.1 - 0.00046 20.5 6.7 0.063 13.5 0.0 3.3 4 0 0 4 4 4 2 AAA domain ArgK PF03308.11 EWM27286.1 - 0.00084 18.1 0.4 0.41 9.3 0.0 2.3 2 0 0 2 2 2 2 ArgK protein AAA_22 PF13401.1 EWM27286.1 - 0.00089 19.4 2.1 0.82 9.8 0.1 3.6 3 1 0 3 3 3 1 AAA domain DUF258 PF03193.11 EWM27286.1 - 0.00099 18.3 0.1 0.66 9.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 EWM27286.1 - 0.0022 17.4 0.6 0.82 9.0 0.0 2.5 2 0 0 2 2 2 1 AAA-like domain AAA_28 PF13521.1 EWM27286.1 - 0.0023 17.9 0.3 1.9 8.4 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 EWM27286.1 - 0.016 15.1 5.1 0.48 10.3 0.1 3.1 2 2 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 EWM27286.1 - 0.035 14.9 0.5 0.035 14.9 0.4 3.9 3 2 0 3 3 3 0 AAA domain AAA_13 PF13166.1 EWM27286.1 - 0.044 12.2 0.7 9.4 4.5 0.0 3.4 4 1 0 4 4 4 0 AAA domain AAA_15 PF13175.1 EWM27286.1 - 0.044 12.8 0.0 18 4.1 0.0 3.3 4 0 0 4 4 4 0 AAA ATPase domain Dynamin_N PF00350.18 EWM27286.1 - 0.051 13.4 0.2 12 5.6 0.1 2.5 2 0 0 2 2 2 0 Dynamin family AAA_14 PF13173.1 EWM27286.1 - 0.063 13.1 0.1 1.7 8.5 0.0 3.0 4 0 0 4 4 4 0 AAA domain AAA_33 PF13671.1 EWM27286.1 - 0.11 12.3 0.3 8.7 6.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain HBS1_N PF08938.5 EWM27286.1 - 0.12 12.5 0.2 0.26 11.4 0.1 1.5 1 0 0 1 1 1 0 HBS1 N-terminus DLIC PF05783.6 EWM27286.1 - 0.19 10.3 4.5 3.1 6.3 0.0 2.8 3 0 0 3 3 3 0 Dynein light intermediate chain (DLIC) NB-ARC PF00931.17 EWM27286.1 - 0.29 9.9 2.4 0.97 8.2 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain MobB PF03205.9 EWM27286.1 - 0.5 10.0 5.5 2.1 8.0 0.3 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_ATPase PF09818.4 EWM27286.1 - 0.66 8.4 1.9 9.2 4.7 0.0 2.3 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_19 PF13245.1 EWM27286.1 - 0.75 9.5 3.9 7.6 6.3 0.1 2.7 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 EWM27286.1 - 6 6.5 5.9 6.2 6.4 0.1 2.3 2 0 0 2 2 2 0 NACHT domain PLDc_N PF13396.1 EWM27287.1 - 0.068 12.8 0.1 0.068 12.8 0.1 2.1 2 0 0 2 2 2 0 Phospholipase_D-nuclease N-terminal TB2_DP1_HVA22 PF03134.14 EWM27288.1 - 6.1e-13 48.3 8.4 7.2e-05 22.4 0.0 4.1 3 1 0 3 3 3 3 TB2/DP1, HVA22 family YchF-GTPase_C PF06071.8 EWM27290.1 - 6.2e-38 128.4 1.2 1.4e-37 127.3 0.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EWM27290.1 - 4.5e-17 62.0 0.0 2e-16 60.0 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EWM27290.1 - 1.7e-07 30.6 0.0 3.7e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B HAUS-augmin3 PF14932.1 EWM27290.1 - 0.0088 15.2 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 CHAD PF05235.9 EWM27290.1 - 0.014 14.9 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 CHAD domain Cas_DxTHG PF09455.5 EWM27290.1 - 0.029 13.5 0.2 0.043 12.9 0.1 1.1 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family Vps39_2 PF10367.4 EWM27290.1 - 0.074 13.2 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 TGS PF02824.16 EWM27290.1 - 0.086 12.6 0.0 0.24 11.2 0.0 1.7 1 1 0 1 1 1 0 TGS domain MIT PF04212.13 EWM27290.1 - 0.13 12.1 1.7 0.3 10.9 1.2 1.6 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain CRAL_TRIO PF00650.15 EWM27291.1 - 2.1e-31 108.5 0.0 2.9e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EWM27291.1 - 2e-11 44.0 0.0 2.9e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Cupin_8 PF13621.1 EWM27292.1 - 1.1e-20 74.2 1.6 3.9e-20 72.4 0.0 2.1 2 0 0 2 2 2 1 Cupin-like domain JmjC PF02373.17 EWM27292.1 - 1.2e-20 73.8 0.0 4e-20 72.1 0.0 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase DUF755 PF05501.6 EWM27292.1 - 0.02 14.9 12.1 0.035 14.1 8.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Cupin_2 PF07883.6 EWM27292.1 - 0.09 12.2 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 Cupin domain Peptidase_S49_N PF08496.5 EWM27292.1 - 4.4 7.0 6.9 6.7 6.4 4.1 1.7 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Ribosomal_L17 PF01196.14 EWM27294.1 - 2.3e-36 124.2 0.5 2.8e-36 123.9 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L17 Acetyltransf_1 PF00583.19 EWM27295.1 - 9.4e-35 118.5 0.2 4.8e-16 58.5 0.1 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EWM27295.1 - 5.8e-21 74.8 0.0 1.7e-09 37.8 0.0 2.4 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EWM27295.1 - 3.2e-19 68.8 0.0 4.2e-10 39.6 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EWM27295.1 - 2.5e-17 63.3 0.0 1.4e-07 31.7 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 EWM27295.1 - 2.6e-14 52.7 0.0 5.7e-06 25.9 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_8 PF13523.1 EWM27295.1 - 1.3e-13 51.0 0.0 1.7e-06 28.0 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EWM27295.1 - 1.2e-11 44.5 0.0 2.6e-07 30.5 0.0 3.2 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EWM27295.1 - 1.4e-09 38.1 0.0 0.0002 21.3 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EWM27295.1 - 0.00043 20.1 0.1 1.3 8.9 0.0 2.4 2 0 0 2 2 2 2 GCN5-related N-acetyl-transferase DUF3749 PF12568.3 EWM27295.1 - 0.0015 18.1 0.0 2.3 7.8 0.0 2.6 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.1 EWM27295.1 - 0.018 14.3 0.0 5.6 6.2 0.0 2.2 2 0 0 2 2 2 0 GNAT acetyltransferase 2 ABC_tran PF00005.22 EWM27296.1 - 1.6e-43 148.3 0.2 2.6e-21 76.3 0.0 3.0 3 1 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 EWM27296.1 - 2.7e-24 84.8 2.3 2.7e-24 84.8 1.6 3.5 5 0 0 5 5 3 1 ABC transporter AAA_21 PF13304.1 EWM27296.1 - 1.1e-18 68.2 8.4 4e-07 30.3 0.1 4.5 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 EWM27296.1 - 2e-13 50.0 1.2 5.6e-05 22.4 0.0 3.5 2 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EWM27296.1 - 1.6e-08 34.7 2.8 0.0023 17.9 0.2 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.1 EWM27296.1 - 2.7e-08 33.3 4.7 0.029 13.4 0.0 4.4 3 2 1 4 4 4 3 AAA ATPase domain AAA_22 PF13401.1 EWM27296.1 - 4.9e-07 29.9 0.3 0.035 14.2 0.1 3.1 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EWM27296.1 - 8.1e-07 29.8 2.4 0.062 14.1 0.0 3.5 3 1 0 4 4 2 2 AAA domain Miro PF08477.8 EWM27296.1 - 2.6e-06 27.9 0.0 0.052 14.0 0.1 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_28 PF13521.1 EWM27296.1 - 3.4e-06 27.1 0.5 0.0035 17.3 0.1 3.1 2 1 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EWM27296.1 - 6.7e-06 25.9 0.6 0.0031 17.4 0.0 3.6 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EWM27296.1 - 6.7e-06 25.5 0.0 0.013 15.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.7 EWM27296.1 - 8.6e-06 25.5 0.1 0.024 14.2 0.0 2.5 2 0 0 2 2 2 2 NACHT domain MobB PF03205.9 EWM27296.1 - 5e-05 23.0 0.0 0.35 10.5 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EWM27296.1 - 0.00017 21.4 0.4 1.6 8.6 0.1 4.1 3 1 1 4 4 4 2 AAA domain AAA_25 PF13481.1 EWM27296.1 - 0.00018 20.9 0.7 0.079 12.3 0.0 3.0 3 1 0 3 3 2 1 AAA domain DUF258 PF03193.11 EWM27296.1 - 0.0002 20.6 0.0 0.1 11.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EWM27296.1 - 0.00031 20.6 0.2 0.048 13.6 0.1 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_19 PF13245.1 EWM27296.1 - 0.0011 18.6 0.0 3.6 7.4 0.0 3.4 3 0 0 3 3 3 1 Part of AAA domain cobW PF02492.14 EWM27296.1 - 0.0012 18.3 0.2 0.91 8.9 0.1 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 EWM27296.1 - 0.0018 17.9 0.7 4.2 7.1 0.0 4.3 5 0 0 5 5 4 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.9 EWM27296.1 - 0.0019 17.2 0.2 0.48 9.3 0.0 2.8 2 1 0 2 2 2 1 KAP family P-loop domain AAA_10 PF12846.2 EWM27296.1 - 0.0022 17.4 0.1 0.36 10.2 0.0 2.7 2 0 0 2 2 2 1 AAA-like domain ArgK PF03308.11 EWM27296.1 - 0.0024 16.7 0.1 0.25 10.0 0.0 2.4 2 0 0 2 2 2 1 ArgK protein AAA_33 PF13671.1 EWM27296.1 - 0.0032 17.3 0.3 1.8 8.4 0.0 3.2 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EWM27296.1 - 0.0033 16.3 0.1 1 8.1 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.24 EWM27296.1 - 0.0033 17.6 0.0 3.6 7.7 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EWM27296.1 - 0.0061 16.7 0.1 7.4 6.7 0.0 3.2 2 1 1 3 3 3 0 RNA helicase NTPase_1 PF03266.10 EWM27296.1 - 0.0075 15.9 0.1 5.5 6.6 0.0 2.8 2 0 0 2 2 2 0 NTPase Pox_A32 PF04665.7 EWM27296.1 - 0.024 13.9 0.2 5.6 6.1 0.0 2.8 3 0 0 3 3 3 0 Poxvirus A32 protein AAA_18 PF13238.1 EWM27296.1 - 0.029 14.6 8.6 0.65 10.2 0.0 4.0 4 1 0 4 4 3 0 AAA domain Arch_ATPase PF01637.13 EWM27296.1 - 0.031 13.9 3.1 2.4 7.7 0.1 3.0 3 1 0 3 3 3 0 Archaeal ATPase DUF87 PF01935.12 EWM27296.1 - 0.04 13.7 0.0 0.04 13.7 0.0 3.2 4 0 0 4 4 3 0 Domain of unknown function DUF87 Dynamin_N PF00350.18 EWM27296.1 - 0.18 11.6 0.0 0.18 11.6 0.0 3.4 4 1 0 4 4 2 0 Dynamin family AAA_24 PF13479.1 EWM27296.1 - 0.21 11.1 2.8 7.6 6.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.1 EWM27296.1 - 0.3 11.3 0.1 0.3 11.3 0.0 4.3 3 1 0 3 3 2 0 AAA domain ATP-grasp_4 PF13535.1 EWM27297.1 - 1.2e-30 106.6 0.0 1.9e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 EWM27297.1 - 8.7e-08 31.9 0.0 1.4e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.9 EWM27297.1 - 4.4e-07 29.8 0.0 7.6e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EWM27297.1 - 3e-06 26.2 0.0 7.5e-06 24.9 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon GSH-S_ATP PF02955.11 EWM27297.1 - 0.033 13.3 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain DNA_pol_E_B PF04042.11 EWM27299.1 - 1.1e-35 122.8 1.7 1.4e-35 122.4 1.2 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DUF2749 PF10907.3 EWM27299.1 - 0.035 13.9 0.0 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) Mt_ATP-synt_D PF05873.7 EWM27301.1 - 1.1e-07 31.5 3.2 8.2e-07 28.7 1.9 2.1 1 1 1 2 2 2 1 ATP synthase D chain, mitochondrial (ATP5H) Myb_DNA-bind_3 PF12776.2 EWM27301.1 - 0.014 16.0 1.7 0.045 14.3 0.0 2.4 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Rieske PF00355.21 EWM27302.1 - 0.089 12.3 0.2 0.18 11.4 0.2 1.4 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain CTNNB1_binding PF08347.6 EWM27304.1 - 1.1 9.4 3.5 1.5 9.0 2.4 1.3 1 0 0 1 1 1 0 N-terminal CTNNB1 binding Apyrase PF06079.6 EWM27305.1 - 2.1e-34 119.0 0.0 2.6e-34 118.6 0.0 1.0 1 0 0 1 1 1 1 Apyrase RNA_pol_Rpo13 PF12136.3 EWM27306.1 - 2.8e-05 23.6 12.2 0.019 14.6 3.9 2.8 2 0 0 2 2 2 2 RNA polymerase Rpo13 subunit HTH domain CPSF_A PF03178.10 EWM27308.1 - 2.3e-24 86.0 0.0 3.2e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 CPSF A subunit region DUF547 PF04784.9 EWM27309.1 - 0.00024 20.9 0.0 0.00031 20.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF547 Pkinase PF00069.20 EWM27310.1 - 8.4e-32 110.3 0.0 1.3e-16 60.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EWM27310.1 - 1.3e-18 67.0 0.0 7.4e-09 35.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase MMS1_N PF10433.4 EWM27312.1 - 1.3e-05 23.6 0.0 1.6e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Cpn60_TCP1 PF00118.19 EWM27313.1 - 2.5e-36 125.3 0.4 6.9e-36 123.9 0.3 1.6 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Aa_trans PF01490.13 EWM27314.1 - 5.1e-62 209.6 7.7 3.6e-33 114.6 0.2 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EWM27314.1 - 9.2e-05 21.4 0.9 9.2e-05 21.4 0.6 2.7 3 0 0 3 3 3 2 Tryptophan/tyrosine permease family Cpn60_TCP1 PF00118.19 EWM27315.1 - 2.3e-46 158.4 0.2 2.9e-46 158.1 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Myb_DNA-binding PF00249.26 EWM27317.1 - 2.8e-07 30.4 0.3 9e-07 28.8 0.2 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Nop14 PF04147.7 EWM27317.1 - 0.052 11.4 19.8 0.065 11.1 13.7 1.2 1 0 0 1 1 1 0 Nop14-like family MADF_DNA_bdg PF10545.4 EWM27317.1 - 0.37 11.0 0.0 0.37 11.0 0.0 3.1 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_6 PF13921.1 EWM27317.1 - 0.8 9.8 7.6 0.73 9.9 1.6 3.2 2 1 1 3 3 3 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EWM27318.1 - 3.3e-12 46.3 4.6 2.4e-08 33.9 0.5 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EWM27318.1 - 2.1e-08 34.0 1.2 0.00021 21.2 1.1 2.7 2 1 0 2 2 2 2 Myb-like DNA-binding domain Peptidase_M3_N PF08439.5 EWM27318.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Oligopeptidase F DAO PF01266.19 EWM27319.1 - 8.9e-52 176.1 4.3 4e-51 174.0 3.0 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EWM27319.1 - 2.3e-05 24.3 0.7 0.00029 20.7 0.5 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EWM27319.1 - 3.5e-05 23.7 0.9 0.0015 18.5 0.3 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EWM27319.1 - 0.00011 21.3 0.0 0.00019 20.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.11 EWM27319.1 - 0.0075 15.7 0.4 0.014 14.7 0.3 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Thi4 PF01946.12 EWM27319.1 - 0.0081 15.2 0.4 0.0081 15.2 0.3 2.3 3 0 0 3 3 3 1 Thi4 family Pyr_redox_3 PF13738.1 EWM27319.1 - 0.0099 15.9 0.1 0.077 13.0 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EWM27319.1 - 0.087 12.9 0.1 0.16 12.1 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EWM27319.1 - 0.09 12.4 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain tRNA_Me_trans PF03054.11 EWM27320.1 - 1.3e-93 313.4 0.0 2e-93 312.8 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase SufE PF02657.10 EWM27320.1 - 3.8e-13 49.1 0.0 6.1e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Fe-S metabolism associated domain Asn_synthase PF00733.16 EWM27320.1 - 0.00019 21.0 0.0 0.00039 19.9 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase ThiI PF02568.9 EWM27320.1 - 0.0014 18.0 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.8 EWM27320.1 - 0.1 11.8 0.0 0.26 10.5 0.0 1.6 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Lysine_decarbox PF03641.9 EWM27321.1 - 3.7e-26 91.5 0.0 1.4e-25 89.6 0.0 1.9 2 0 0 2 2 2 1 Possible lysine decarboxylase TPX2 PF06886.6 EWM27321.1 - 0.071 13.1 0.7 0.16 12.0 0.1 1.9 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) Lysine_decarbox PF03641.9 EWM27322.1 - 2.5e-23 82.3 0.1 9.7e-23 80.4 0.0 1.9 2 0 0 2 2 2 1 Possible lysine decarboxylase Retrotrans_gag PF03732.12 EWM27322.1 - 0.026 14.6 0.4 0.049 13.6 0.3 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein TPX2 PF06886.6 EWM27322.1 - 0.069 13.2 0.7 0.16 12.0 0.1 1.8 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) Glyco_hydro_70 PF02324.11 EWM27322.1 - 0.1 10.3 0.0 0.13 9.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 Bacillus_HBL PF05791.6 EWM27323.1 - 0.031 13.6 8.8 0.4 10.0 0.9 3.1 2 2 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF3584 PF12128.3 EWM27323.1 - 1.8 5.8 42.5 3.6 4.8 29.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GBP_C PF02841.9 EWM27323.1 - 6.7 5.7 48.6 4.4 6.3 14.4 2.7 1 1 1 2 2 2 0 Guanylate-binding protein, C-terminal domain Homeobox_KN PF05920.6 EWM27325.1 - 5.7e-12 45.1 0.2 9.5e-12 44.4 0.1 1.4 1 0 0 1 1 1 1 Homeobox KN domain zf-RING_2 PF13639.1 EWM27325.1 - 2e-06 27.4 9.2 8e-06 25.5 6.6 1.8 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EWM27325.1 - 8.5e-06 25.3 4.3 1.4e-05 24.6 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EWM27325.1 - 3.1e-05 23.5 4.9 5e-05 22.8 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Homeobox PF00046.24 EWM27325.1 - 6.1e-05 22.5 0.2 0.00014 21.4 0.0 1.6 2 0 0 2 2 2 1 Homeobox domain zf-C3HC4_2 PF13923.1 EWM27325.1 - 9.1e-05 22.4 5.2 9.1e-05 22.4 3.6 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EWM27325.1 - 0.00018 21.5 3.4 0.00039 20.4 2.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EWM27325.1 - 0.00022 21.0 3.9 0.00043 20.0 2.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EWM27325.1 - 0.0047 16.6 4.3 0.017 14.8 3.1 1.8 1 1 1 2 2 2 1 zinc-RING finger domain PHD PF00628.24 EWM27325.1 - 0.84 9.3 3.3 1.4 8.6 2.3 1.4 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 EWM27325.1 - 3.5 7.6 5.8 6.3 6.8 2.4 2.4 1 1 1 2 2 2 0 FANCL C-terminal domain TIP120 PF08623.5 EWM27326.1 - 3.3e-31 108.1 0.2 2e-29 102.3 0.0 3.0 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 EWM27326.1 - 3e-11 43.4 27.2 4.3e-05 23.7 0.1 8.2 6 1 1 7 7 7 3 HEAT repeats HEAT_EZ PF13513.1 EWM27326.1 - 3.3e-11 43.3 22.6 0.072 13.5 0.0 11.4 9 3 3 12 12 12 3 HEAT-like repeat HEAT PF02985.17 EWM27326.1 - 6.3e-11 41.4 13.7 0.082 13.0 0.0 9.3 9 0 0 9 9 9 3 HEAT repeat Adaptin_N PF01602.15 EWM27326.1 - 7.2e-06 24.5 0.5 0.31 9.3 0.2 5.0 4 1 1 5 5 5 3 Adaptin N terminal region UME PF08064.8 EWM27326.1 - 0.033 14.1 1.1 5.3 7.0 0.1 4.8 7 0 0 7 7 7 0 UME (NUC010) domain CENP-X PF09415.5 EWM27326.1 - 0.048 13.4 0.4 1.8 8.4 0.2 2.9 3 0 0 3 3 3 0 CENP-S associating Centromere protein X HEAT_PBS PF03130.11 EWM27326.1 - 1.5 9.4 10.1 35 5.2 0.1 5.9 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat ClpS PF02617.12 EWM27327.1 - 3.7e-12 45.7 0.0 6.2e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS MCM PF00493.18 EWM27329.1 - 5.8e-130 432.9 0.0 2.7e-116 388.0 0.0 2.1 2 0 0 2 2 2 2 MCM2/3/5 family Mg_chelatase PF01078.16 EWM27329.1 - 1.3e-08 34.2 0.1 3.6e-05 23.0 0.0 3.0 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EWM27329.1 - 1.1e-06 28.3 0.1 6.1e-06 26.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EWM27329.1 - 0.00034 20.2 0.0 0.0015 18.1 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EWM27329.1 - 0.093 12.1 0.0 17 4.8 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Zn-ribbon_8 PF09723.5 EWM27329.1 - 0.11 12.4 2.5 0.22 11.5 1.7 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Asp PF00026.18 EWM27330.1 - 6.8e-32 110.9 0.0 1.3e-31 110.0 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EWM27330.1 - 5.9e-20 71.8 0.9 5.9e-20 71.8 0.6 2.0 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EWM27330.1 - 6.5e-15 55.0 0.1 7.2e-14 51.6 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Atx10homo_assoc PF09759.4 EWM27331.1 - 3.3e-29 100.6 0.2 1.2e-28 98.8 0.0 2.1 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.17 EWM27331.1 - 0.13 12.4 1.1 7.4 6.9 0.1 2.9 2 0 0 2 2 2 0 HEAT repeat TFIID_20kDa PF03847.8 EWM27332.1 - 1.9e-15 56.9 0.0 2.3e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TFIID-18kDa PF02269.11 EWM27332.1 - 0.0054 16.5 0.0 0.0094 15.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CBFD_NFYB_HMF PF00808.18 EWM27332.1 - 0.039 14.0 0.0 0.056 13.5 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Asp_protease_2 PF13650.1 EWM27333.1 - 7.8e-17 61.5 3.0 0.0011 19.4 0.1 4.6 4 0 0 4 4 4 4 Aspartyl protease gag-asp_proteas PF13975.1 EWM27333.1 - 9.8e-11 41.3 2.0 0.0023 17.7 0.0 4.0 4 0 0 4 4 4 3 gag-polyprotein putative aspartyl protease RVP PF00077.15 EWM27333.1 - 0.018 14.9 0.1 21 5.0 0.0 3.9 4 0 0 4 4 4 0 Retroviral aspartyl protease Metallophos PF00149.23 EWM27334.1 - 1.8e-38 131.9 0.0 2.3e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF410 PF04190.8 EWM27335.1 - 1.3e-10 41.3 0.0 0.001 18.6 0.0 3.1 3 1 0 3 3 3 2 Protein of unknown function (DUF410) TPR_7 PF13176.1 EWM27335.1 - 0.018 14.8 0.7 0.26 11.1 0.1 3.1 3 1 1 4 4 4 0 Tetratricopeptide repeat FlbT PF07378.6 EWM27335.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Flagellar protein FlbT Glyco_transf_34 PF05637.7 EWM27337.1 - 1.1e-05 25.1 1.0 0.78 9.1 0.6 3.1 3 0 0 3 3 3 3 galactosyl transferase GMA12/MNN10 family 4HBT PF03061.17 EWM27338.1 - 7.9e-07 29.1 0.0 0.00018 21.5 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily Methyltransf_16 PF10294.4 EWM27339.1 - 2.6e-27 95.3 0.0 3.7e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase DUF938 PF06080.7 EWM27339.1 - 0.0023 17.5 0.0 0.0034 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_23 PF13489.1 EWM27339.1 - 0.0053 16.4 0.0 0.011 15.5 0.0 1.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM27339.1 - 0.0066 17.0 0.0 0.012 16.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EWM27339.1 - 0.024 13.9 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Hema_esterase PF03996.10 EWM27339.1 - 0.085 12.0 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Hemagglutinin esterase Methyltransf_26 PF13659.1 EWM27339.1 - 0.087 12.8 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EWM27339.1 - 0.097 13.1 0.0 0.62 10.5 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain DSPc PF00782.15 EWM27340.1 - 7.2e-30 103.2 0.0 1.2e-29 102.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EWM27340.1 - 0.0007 19.0 0.0 0.001 18.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Acyl_transf_3 PF01757.17 EWM27341.1 - 1.5e-18 66.7 37.7 1.5e-18 66.7 26.1 1.8 2 0 0 2 2 2 1 Acyltransferase family Ctr PF04145.10 EWM27343.1 - 0.09 12.8 0.1 0.22 11.5 0.0 1.5 1 1 1 2 2 2 0 Ctr copper transporter family Scs3p PF10261.4 EWM27345.1 - 0.00097 18.2 0.9 0.002 17.2 0.6 1.5 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM SR-25 PF10500.4 EWM27347.1 - 0.023 14.1 22.0 0.042 13.3 15.2 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 EWM27347.1 - 0.18 11.8 23.9 0.28 11.2 16.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF572 PF04502.8 EWM27347.1 - 0.18 10.9 6.9 0.24 10.5 4.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF605 PF04652.11 EWM27347.1 - 0.58 9.4 15.1 0.74 9.1 10.5 1.1 1 0 0 1 1 1 0 Vta1 like TEX19 PF15553.1 EWM27347.1 - 0.88 9.4 4.4 1.5 8.6 3.0 1.5 1 1 0 1 1 1 0 Testis-expressed protein 19 BUD22 PF09073.5 EWM27347.1 - 0.91 8.5 15.8 1.2 8.0 11.0 1.1 1 0 0 1 1 1 0 BUD22 DUF2217 PF10265.4 EWM27347.1 - 1.7 7.2 7.0 2 7.0 4.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) RAP1 PF07218.6 EWM27347.1 - 1.7 6.6 11.4 2.4 6.1 7.9 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ODV-E18 PF10717.4 EWM27347.1 - 1.8 8.0 6.5 1.7 8.1 3.5 1.7 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Lin-8 PF03353.10 EWM27347.1 - 1.9 7.6 8.4 2.6 7.2 5.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SDA1 PF05285.7 EWM27347.1 - 2.7 7.1 10.0 3.5 6.8 6.9 1.0 1 0 0 1 1 1 0 SDA1 Macoilin PF09726.4 EWM27347.1 - 3.7 5.7 12.8 4.6 5.4 8.9 1.0 1 0 0 1 1 1 0 Transmembrane protein DNA_pol_viral_N PF00242.12 EWM27347.1 - 4.3 6.2 8.7 5.5 5.9 6.0 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain MIP-T3 PF10243.4 EWM27347.1 - 5.7 5.2 10.7 6.7 5.0 7.4 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 bZIP_1 PF00170.16 EWM27349.1 - 1.2e-07 31.6 10.8 2.1e-07 30.7 7.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EWM27349.1 - 9e-06 25.8 8.2 2.2e-05 24.6 5.7 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.10 EWM27349.1 - 0.00045 19.9 12.6 0.00076 19.2 8.7 1.3 1 0 0 1 1 1 1 Basic region leucine zipper Macoilin PF09726.4 EWM27349.1 - 0.0077 14.5 2.7 0.011 14.0 1.8 1.3 1 0 0 1 1 1 1 Transmembrane protein GAS PF13851.1 EWM27349.1 - 0.05 12.7 6.5 0.073 12.2 4.5 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 EWM27349.1 - 0.33 10.5 5.2 0.51 9.9 3.6 1.3 1 0 0 1 1 1 0 IncA protein DUF218 PF02698.12 EWM27350.1 - 8.1e-08 31.9 0.2 3.4e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 DUF218 domain Apolipoprotein PF01442.13 EWM27351.1 - 0.00041 19.9 14.2 0.00073 19.1 3.6 2.4 1 1 2 3 3 3 2 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 EWM27351.1 - 0.00053 20.3 25.7 0.028 14.8 0.2 4.1 1 1 1 3 3 3 3 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 EWM27351.1 - 0.073 13.4 33.5 2.2 8.6 3.9 4.7 1 1 2 3 3 3 0 YtxH-like protein DUF4170 PF13773.1 EWM27351.1 - 0.34 10.8 3.5 0.8 9.6 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4170) DUF948 PF06103.6 EWM27351.1 - 0.54 10.1 3.1 10 6.0 0.0 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) BMFP PF04380.8 EWM27351.1 - 2 8.5 8.4 8.8 6.5 0.5 3.4 3 0 0 3 3 3 0 Membrane fusogenic activity AHH PF14412.1 EWM27351.1 - 5.5 7.0 7.8 13 5.8 0.0 3.2 3 1 0 3 3 3 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH DUF2422 PF10337.4 EWM27351.1 - 6.4 5.4 8.1 11 4.6 5.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2422) DUF4203 PF13886.1 EWM27352.1 - 3.8e-18 65.7 19.6 5.5e-18 65.2 13.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) SPC12 PF06645.8 EWM27352.1 - 4.4 7.1 13.6 0.06 13.1 3.0 2.6 2 1 1 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) RAB3GAP2_N PF14655.1 EWM27354.1 - 0.26 10.2 3.0 0.31 9.9 2.1 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Thaumatin PF00314.12 EWM27355.1 - 0.037 13.4 0.1 0.048 13.1 0.1 1.2 1 0 0 1 1 1 0 Thaumatin family DUF962 PF06127.6 EWM27358.1 - 3.9e-27 93.9 1.3 2.6e-26 91.3 0.9 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Tmemb_18A PF09771.4 EWM27358.1 - 0.37 10.7 2.4 7.6 6.5 0.1 2.6 1 1 2 3 3 3 0 Transmembrane protein 188 Acyl_transf_3 PF01757.17 EWM27359.1 - 1.1e-17 63.8 41.9 1.1e-09 37.5 23.2 2.8 2 1 0 2 2 2 2 Acyltransferase family Hepar_II_III PF07940.8 EWM27359.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Heparinase II/III-like protein PAP_fibrillin PF04755.7 EWM27360.1 - 6.5e-07 29.2 0.0 8.3e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 PAP_fibrillin Peptidase_M76 PF09768.4 EWM27360.1 - 0.13 11.7 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Peptidase M76 family CoA_trans PF01144.18 EWM27361.1 - 3.7e-09 36.0 0.0 4e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 Coenzyme A transferase CoA_trans PF01144.18 EWM27362.1 - 2.2e-85 285.2 0.0 5.9e-76 254.4 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AhpC-TSA PF00578.16 EWM27365.1 - 6.6e-34 116.2 0.1 8e-34 115.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EWM27365.1 - 2.5e-20 72.5 0.1 3.1e-20 72.1 0.1 1.1 1 0 0 1 1 1 1 Redoxin Kelch_4 PF13418.1 EWM27366.1 - 0.01 15.5 0.2 0.024 14.4 0.0 1.7 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_3 PF13415.1 EWM27366.1 - 0.014 15.5 1.6 2.6 8.2 0.0 2.6 3 0 0 3 3 3 0 Galactose oxidase, central domain FIST PF08495.5 EWM27366.1 - 0.14 11.2 0.1 0.33 10.0 0.0 1.5 2 0 0 2 2 2 0 FIST N domain Lectin_leg-like PF03388.8 EWM27367.1 - 1.1e-33 116.3 0.1 1.4e-33 116.0 0.1 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 EWM27367.1 - 9.4e-06 25.1 0.0 1.7e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 Legume lectin domain AAA PF00004.24 EWM27368.1 - 7.8e-21 74.6 0.0 1.5e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EWM27368.1 - 3.8e-08 33.1 0.0 1.8e-07 30.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EWM27368.1 - 1.3e-05 25.9 1.3 0.00037 21.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EWM27368.1 - 3.3e-05 23.9 0.2 3.3e-05 23.9 0.1 2.6 2 2 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EWM27368.1 - 0.00013 22.0 0.2 0.023 14.8 0.0 3.5 2 2 1 3 3 3 1 AAA domain LON PF02190.11 EWM27368.1 - 0.00033 20.4 0.9 0.00042 20.0 0.0 1.5 2 0 0 2 2 1 1 ATP-dependent protease La (LON) domain AAA_PrkA PF08298.6 EWM27368.1 - 0.00042 19.1 0.0 0.0014 17.3 0.0 1.8 2 0 0 2 2 2 1 PrkA AAA domain RuvB_N PF05496.7 EWM27368.1 - 0.0015 17.6 0.4 0.012 14.6 0.0 2.4 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_23 PF13476.1 EWM27368.1 - 0.0046 17.2 2.0 0.12 12.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EWM27368.1 - 0.0047 16.5 0.0 0.019 14.5 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EWM27368.1 - 0.0057 15.8 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 EWM27368.1 - 0.0061 16.0 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein SKI PF01202.17 EWM27368.1 - 0.012 15.5 2.7 0.075 12.9 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase AAA_33 PF13671.1 EWM27368.1 - 0.012 15.4 1.0 0.033 14.0 0.0 2.2 3 0 0 3 3 3 0 AAA domain NACHT PF05729.7 EWM27368.1 - 0.016 14.8 0.0 0.091 12.4 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.1 EWM27368.1 - 0.023 14.6 0.0 0.069 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EWM27368.1 - 0.023 15.0 0.1 0.023 15.0 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EWM27368.1 - 0.027 14.1 0.7 0.059 13.1 0.1 1.9 2 0 0 2 2 1 0 Part of AAA domain RNA_helicase PF00910.17 EWM27368.1 - 0.034 14.3 0.0 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 RNA helicase UPF0079 PF02367.12 EWM27368.1 - 0.042 13.4 0.0 0.08 12.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 EWM27368.1 - 0.062 12.8 0.3 0.11 12.0 0.2 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EWM27368.1 - 0.08 12.3 0.0 0.23 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 EWM27368.1 - 0.13 11.4 0.1 3.5 6.8 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ABC_tran PF00005.22 EWM27368.1 - 0.16 12.2 1.0 1 9.6 0.0 2.2 2 0 0 2 2 2 0 ABC transporter MobB PF03205.9 EWM27368.1 - 0.19 11.4 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Abi PF02517.11 EWM27369.1 - 3.5e-10 39.8 1.7 3.5e-10 39.8 1.2 1.8 2 0 0 2 2 2 1 CAAX protease self-immunity Lon_C PF05362.8 EWM27370.1 - 2.7e-72 242.4 2.2 2.7e-48 164.0 0.3 2.1 2 0 0 2 2 2 2 Lon protease (S16) C-terminal proteolytic domain ChlI PF13541.1 EWM27370.1 - 4.2e-07 29.5 0.0 2.4e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase Birna_VP4 PF01768.11 EWM27370.1 - 0.0017 17.4 0.1 0.0029 16.6 0.1 1.3 1 0 0 1 1 1 1 Birnavirus VP4 protein ABC_membrane PF00664.18 EWM27371.1 - 1.7e-56 191.6 15.9 8.5e-31 107.3 4.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EWM27371.1 - 6.6e-08 32.9 0.0 1.4e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter DUF1824 PF08854.5 EWM27371.1 - 0.15 11.7 0.0 1.5 8.4 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1824) ABC_membrane PF00664.18 EWM27372.1 - 1.8e-40 139.1 10.6 4.3e-25 88.6 2.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EWM27372.1 - 1.2e-39 135.7 0.0 4e-29 101.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EWM27372.1 - 2.3e-07 31.0 0.0 0.0039 17.1 0.1 3.3 2 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 EWM27372.1 - 9.5e-07 28.2 0.1 0.039 13.1 0.0 3.0 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 EWM27372.1 - 0.00034 20.4 0.3 1.1 9.1 0.0 3.1 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 EWM27372.1 - 0.093 12.6 0.1 0.26 11.2 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF1772 PF08592.6 EWM27373.1 - 2.2 7.9 5.1 9.1 6.0 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) OTU PF02338.14 EWM27374.1 - 1.1e-21 77.6 0.3 2.5e-21 76.4 0.0 1.7 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EWM27374.1 - 5.7e-06 25.8 0.0 0.018 14.4 0.0 2.3 2 0 0 2 2 2 2 Peptidase C65 Otubain OHA PF14418.1 EWM27374.1 - 0.06 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 OST-HTH Associated domain Pex14_N PF04695.8 EWM27375.1 - 0.04 13.9 12.3 0.06 13.3 8.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3353 PF11833.3 EWM27375.1 - 0.11 11.9 5.6 0.19 11.1 3.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3353) Med15 PF09606.5 EWM27375.1 - 0.19 9.9 37.1 0.2 9.8 25.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 EWM27375.1 - 0.25 11.2 16.0 0.3 10.9 11.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2360 PF10152.4 EWM27375.1 - 0.28 11.4 9.2 0.33 11.2 6.4 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) RNA_pol_3_Rpc31 PF11705.3 EWM27375.1 - 0.48 10.3 5.7 0.6 10.0 3.9 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF605 PF04652.11 EWM27375.1 - 1.4 8.2 17.3 1.6 8.0 12.0 1.1 1 0 0 1 1 1 0 Vta1 like Suf PF05843.9 EWM27375.1 - 3.7 7.1 16.7 4.7 6.8 11.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4175 PF13779.1 EWM27375.1 - 4.9 4.7 28.4 5 4.6 19.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF1183 PF06682.7 EWM27375.1 - 6.9 6.1 15.7 9.2 5.7 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) BUD22 PF09073.5 EWM27382.1 - 0.045 12.8 28.1 0.049 12.7 19.5 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 EWM27382.1 - 3.9 5.2 44.2 5.2 4.8 30.6 1.3 1 0 0 1 1 1 0 Nop14-like family Peptidase_C14 PF00656.17 EWM27383.1 - 8.8e-37 127.1 0.0 1.5e-36 126.3 0.0 1.3 1 0 0 1 1 1 1 Caspase domain NOT2_3_5 PF04153.13 EWM27383.1 - 5.7e-11 42.4 2.6 2.2e-10 40.5 1.5 2.1 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Metallophos_C PF14008.1 EWM27385.1 - 8.2e-14 51.4 0.0 1.6e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.23 EWM27385.1 - 5.5e-11 42.2 0.0 1.8e-10 40.5 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PP2C PF00481.16 EWM27389.1 - 2.1e-75 253.3 0.1 6.1e-59 199.4 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EWM27389.1 - 0.00031 20.1 0.1 0.0074 15.7 0.0 2.3 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.7 EWM27389.1 - 0.015 14.9 0.0 0.24 11.0 0.0 2.2 1 1 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) DGF-1_C PF11040.3 EWM27389.1 - 2.9 7.8 5.1 8.2 6.3 0.1 3.1 3 0 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus CENP-T PF15511.1 EWM27390.1 - 0.015 14.6 20.1 0.018 14.3 13.9 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T MFMR PF07777.6 EWM27390.1 - 0.062 13.2 8.6 0.1 12.5 6.0 1.2 1 0 0 1 1 1 0 G-box binding protein MFMR Nha1_C PF08619.5 EWM27390.1 - 0.087 12.0 19.4 0.12 11.6 13.5 1.2 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus DUF1510 PF07423.6 EWM27390.1 - 0.75 9.1 22.7 1.2 8.5 15.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SDA1 PF05285.7 EWM27390.1 - 1.2 8.3 37.4 1.7 7.8 25.9 1.3 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 EWM27390.1 - 4.9 5.0 32.8 7.1 4.5 22.7 1.2 1 0 0 1 1 1 0 CDC45-like protein CENP-T PF15511.1 EWM27391.1 - 0.012 14.8 19.9 0.015 14.5 13.8 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T MFMR PF07777.6 EWM27391.1 - 0.063 13.2 8.6 0.1 12.5 6.0 1.2 1 0 0 1 1 1 0 G-box binding protein MFMR Nha1_C PF08619.5 EWM27391.1 - 0.088 12.0 19.4 0.12 11.6 13.5 1.2 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus DUF1510 PF07423.6 EWM27391.1 - 1.2 8.4 23.4 1.8 7.8 16.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SDA1 PF05285.7 EWM27391.1 - 1.2 8.3 37.4 1.7 7.8 25.9 1.3 1 0 0 1 1 1 0 SDA1 FLO_LFY PF01698.11 EWM27391.1 - 2.8 6.6 9.9 3.9 6.2 6.8 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein CDC45 PF02724.9 EWM27391.1 - 4.8 5.0 32.8 7.1 4.5 22.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Kelch_4 PF13418.1 EWM27393.1 - 5.1e-10 38.9 3.5 0.0045 16.7 0.1 4.0 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_3 PF13415.1 EWM27393.1 - 0.00082 19.4 9.5 2.8 8.2 0.0 5.6 6 0 0 6 6 6 3 Galactose oxidase, central domain Glyco_transf_49 PF13896.1 EWM27394.1 - 2.7e-37 128.5 0.0 5.7e-31 107.7 0.0 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan BNR PF02012.15 EWM27397.1 - 0.92 9.6 5.4 0.29 11.1 1.0 2.5 2 0 0 2 2 2 0 BNR/Asp-box repeat SoxG PF04268.7 EWM27398.1 - 0.09 12.6 0.1 2.1 8.2 0.0 2.1 1 1 1 2 2 2 0 Sarcosine oxidase, gamma subunit family adh_short_C2 PF13561.1 EWM27400.1 - 1.2e-23 84.1 0.2 1.5e-23 83.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EWM27400.1 - 8.9e-23 81.0 1.2 1.2e-22 80.5 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EWM27400.1 - 8.2e-07 28.8 0.2 1.5e-06 28.0 0.1 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_7 PF13241.1 EWM27400.1 - 0.02 15.1 0.1 0.06 13.5 0.1 1.8 1 1 0 1 1 1 0 Putative NAD(P)-binding RVT_1 PF00078.22 EWM27401.1 - 8.9e-07 28.4 0.0 1.3e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HNH_2 PF13391.1 EWM27401.1 - 0.14 11.9 0.1 21 4.9 0.0 2.4 2 0 0 2 2 2 0 HNH endonuclease Ank_2 PF12796.2 EWM27403.1 - 4.6e-26 90.9 0.1 6.8e-17 61.5 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EWM27403.1 - 9.5e-26 88.2 2.2 2.6e-07 30.1 0.1 5.6 5 1 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 EWM27403.1 - 7.3e-23 80.0 0.5 2.1e-06 27.7 0.0 3.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EWM27403.1 - 7.5e-23 80.4 0.1 1e-08 35.4 0.0 4.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM27403.1 - 1.5e-18 65.0 0.2 6.3e-05 22.8 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Pkinase PF00069.20 EWM27404.1 - 9e-08 31.5 0.0 3.2e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 EWM27404.1 - 0.024 13.6 0.0 0.03 13.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EWM27404.1 - 0.083 12.6 0.0 0.49 10.0 0.0 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 EWM27404.1 - 0.089 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.12 EWM27404.1 - 0.17 10.9 0.1 0.93 8.5 0.1 1.9 1 1 0 1 1 1 0 Protein tyrosine kinase HopJ PF08888.6 EWM27405.1 - 9.5e-34 115.7 0.0 1.5e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 HopJ type III effector protein Voltage_CLC PF00654.15 EWM27406.1 - 2.9e-75 253.5 23.8 2.9e-75 253.5 16.5 1.6 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EWM27406.1 - 8.7e-09 35.0 0.6 0.0011 18.7 0.0 3.2 3 0 0 3 3 3 2 CBS domain AAA PF00004.24 EWM27407.1 - 4.7e-18 65.6 0.0 7.5e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EWM27407.1 - 0.00043 20.4 0.0 0.0026 17.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EWM27407.1 - 0.0022 17.7 0.6 0.0096 15.6 0.0 2.2 2 1 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 EWM27407.1 - 0.0025 17.8 0.5 0.0092 15.9 0.3 2.1 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.16 EWM27407.1 - 0.051 12.7 0.0 0.094 11.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EWM27407.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EWM27407.1 - 0.19 10.7 0.0 0.29 10.1 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 EWM27407.1 - 0.24 10.7 0.2 2.2 7.6 0.1 2.1 1 1 0 1 1 1 0 AAA domain adh_short PF00106.20 EWM27409.1 - 1.3e-09 38.1 0.1 1.1e-05 25.4 0.2 3.4 3 1 0 3 3 3 2 short chain dehydrogenase NAD_binding_10 PF13460.1 EWM27409.1 - 0.00028 20.9 0.2 0.0024 17.8 0.1 2.1 2 0 0 2 2 2 1 NADH(P)-binding KR PF08659.5 EWM27409.1 - 0.0019 17.9 0.2 0.0043 16.7 0.1 1.6 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EWM27409.1 - 0.014 15.1 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EWM27409.1 - 0.065 12.6 0.0 5.3 6.4 0.0 2.3 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EWM27409.1 - 0.18 10.8 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain YTH PF04146.10 EWM27410.1 - 1.8e-40 137.7 0.0 3.2e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 YT521-B-like domain Dev_Cell_Death PF10539.4 EWM27410.1 - 8.8e-16 57.6 0.0 1.8e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Development and cell death domain zf-CCCH PF00642.19 EWM27410.1 - 1.8e-10 40.2 22.3 1.3e-06 27.9 0.3 5.1 5 0 0 5 5 5 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Med3 PF11593.3 EWM27410.1 - 6.1 5.9 16.5 4.2 6.5 3.2 2.6 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Mad3_BUB1_I PF08311.7 EWM27411.1 - 1.6e-36 124.8 0.7 2.3e-36 124.3 0.5 1.3 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Ank_2 PF12796.2 EWM27412.1 - 5.4e-42 142.0 0.0 1.3e-14 54.2 0.0 3.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EWM27412.1 - 1.1e-27 94.4 0.0 3.7e-09 35.9 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 EWM27412.1 - 5.2e-24 83.7 0.3 2.3e-06 27.6 0.0 4.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EWM27412.1 - 6.6e-23 80.6 0.1 4.9e-10 39.6 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM27412.1 - 7.3e-17 59.7 0.0 0.00013 21.8 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat FeThRed_A PF02941.10 EWM27413.1 - 0.00024 20.9 0.0 0.00037 20.3 0.0 1.3 1 0 0 1 1 1 1 Ferredoxin thioredoxin reductase variable alpha chain AtpR PF12966.2 EWM27413.1 - 0.073 13.2 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 N-ATPase, AtpR subunit DUF1068 PF06364.7 EWM27414.1 - 0.0029 17.2 0.0 0.0054 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1068) PSII_Pbs27 PF13326.1 EWM27414.1 - 0.086 12.8 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Photosystem II Pbs27 DUF1068 PF06364.7 EWM27415.1 - 0.0038 16.8 0.0 0.0054 16.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1068) PSII_Pbs27 PF13326.1 EWM27415.1 - 0.11 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Photosystem II Pbs27 Mito_carr PF00153.22 EWM27416.1 - 1.4e-39 133.6 7.6 2.7e-13 49.4 0.0 4.3 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF1992 PF09350.5 EWM27416.1 - 1.6e-13 50.2 0.0 3.5e-12 45.9 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) DREPP PF05558.7 EWM27416.1 - 0.3 10.9 8.1 0.6 9.9 5.6 1.4 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide OAD_gamma PF04277.8 EWM27416.1 - 1.7 9.0 7.7 3.7 7.9 5.3 1.6 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain PFK PF00365.15 EWM27417.1 - 1.5e-36 125.8 1.0 3e-21 75.6 0.0 2.9 3 0 0 3 3 3 2 Phosphofructokinase Asp PF00026.18 EWM27418.1 - 4.7e-39 134.4 0.0 1.3e-38 133.0 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EWM27418.1 - 4.5e-07 29.5 0.0 8.4e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 EWM27418.1 - 9.5e-06 25.6 0.0 2.7e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Peptidase_U32 PF01136.14 EWM27418.1 - 0.022 13.6 0.3 0.22 10.4 0.0 2.1 2 0 0 2 2 2 0 Peptidase family U32 Daxx PF03344.10 EWM27418.1 - 3.8 5.8 6.6 5.8 5.2 4.6 1.2 1 0 0 1 1 1 0 Daxx Family Exo_endo_phos PF03372.18 EWM27419.1 - 1e-08 35.4 0.4 7.9e-06 25.9 0.0 2.4 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Methyltransf_26 PF13659.1 EWM27420.1 - 3.8e-12 46.2 0.0 8.3e-12 45.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM27420.1 - 0.00013 22.5 0.0 0.0003 21.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM27420.1 - 0.00016 22.0 0.0 0.00032 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EWM27420.1 - 0.00061 19.2 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EWM27420.1 - 0.00074 19.1 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DnaJ_CXXCXGXG PF00684.14 EWM27420.1 - 0.0032 17.4 5.2 0.17 11.9 0.3 2.6 2 0 0 2 2 2 2 DnaJ central domain Methyltransf_25 PF13649.1 EWM27420.1 - 0.0056 17.0 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EWM27420.1 - 0.048 12.7 0.0 0.082 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_23 PF13489.1 EWM27420.1 - 0.13 11.9 0.0 0.28 10.9 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain MetW PF07021.7 EWM27420.1 - 0.18 11.1 0.3 0.47 9.8 0.1 1.7 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW GST_C_3 PF14497.1 EWM27422.1 - 2e-05 25.0 0.2 6.8e-05 23.2 0.1 2.1 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EWM27422.1 - 3.9e-05 23.5 0.0 0.0001 22.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EWM27422.1 - 0.0028 17.5 0.1 0.0071 16.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EWM27422.1 - 0.04 14.0 0.0 0.15 12.2 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain DUF677 PF05055.7 EWM27422.1 - 0.11 11.1 0.0 0.82 8.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF677) Mo-co_dimer PF03404.11 EWM27423.1 - 2.2e-37 127.6 0.1 2.8e-37 127.2 0.1 1.1 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 EWM27423.1 - 5.9e-16 58.3 0.1 1.1e-15 57.5 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain BNR PF02012.15 EWM27423.1 - 0.065 13.0 0.0 0.065 13.0 0.0 2.4 2 0 0 2 2 2 0 BNR/Asp-box repeat FA_desaturase PF00487.19 EWM27424.1 - 0.039 13.3 0.5 0.053 12.9 0.4 1.2 1 0 0 1 1 1 0 Fatty acid desaturase Cyt-b5 PF00173.23 EWM27425.1 - 2.1e-11 43.4 0.0 3.3e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-Tim10_DDP PF02953.10 EWM27429.1 - 2.8e-16 58.5 2.0 5.3e-16 57.6 1.4 1.4 1 0 0 1 1 1 1 Tim10/DDP family zinc finger TAF4 PF05236.9 EWM27429.1 - 0.13 11.5 0.1 0.18 11.0 0.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family GATase PF00117.23 EWM27434.1 - 3.6e-27 95.0 0.0 4.6e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EWM27434.1 - 0.043 13.2 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase C26 LST1 PF05083.8 EWM27435.1 - 0.064 13.2 0.1 0.43 10.5 0.1 2.1 2 0 0 2 2 2 0 LST-1 protein PAS_7 PF12860.2 EWM27436.1 - 0.58 10.1 3.1 1.3 9.0 0.1 2.5 2 1 0 2 2 2 0 PAS fold tRNA_m1G_MT PF01746.16 EWM27437.1 - 0.038 13.5 0.0 0.1 12.2 0.0 1.7 1 1 0 1 1 1 0 tRNA (Guanine-1)-methyltransferase SieB PF14163.1 EWM27437.1 - 4.2 6.9 5.7 9.3 5.8 4.0 1.6 1 1 0 1 1 1 0 Superinfection exclusion protein B DUF1049 PF06305.6 EWM27438.1 - 0.2 11.1 0.8 0.29 10.6 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF605 PF04652.11 EWM27438.1 - 0.25 10.7 4.8 0.27 10.5 3.3 1.2 1 0 0 1 1 1 0 Vta1 like Herpes_gE PF02480.11 EWM27438.1 - 0.28 9.4 1.4 0.48 8.6 0.0 2.0 1 1 1 3 3 3 0 Alphaherpesvirus glycoprotein E Chorismate_bind PF00425.13 EWM27439.1 - 9.1e-85 284.0 0.0 1.4e-84 283.4 0.0 1.3 1 1 0 1 1 1 1 chorismate binding enzyme MdcG PF10620.4 EWM27439.1 - 0.35 10.3 1.7 1.8 8.0 0.5 2.2 2 1 0 2 2 2 0 Phosphoribosyl-dephospho-CoA transferase MdcG UCH PF00443.24 EWM27440.1 - 9.8e-60 201.9 0.0 1.9e-59 201.0 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EWM27440.1 - 9.8e-26 90.8 0.0 1e-15 57.9 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L18e PF00828.14 EWM27441.1 - 6.5e-15 55.6 0.1 1.2e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Cation_ATPase_C PF00689.16 EWM27443.1 - 0.0067 15.9 0.2 0.0083 15.6 0.1 1.1 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Glyco_transf_8 PF01501.15 EWM27444.1 - 3.2e-09 36.4 0.1 1.7e-08 34.0 0.1 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EWM27444.1 - 0.01 15.2 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative DcpS_C PF11969.3 EWM27445.1 - 3.9e-17 62.5 0.9 6.4e-17 61.8 0.6 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EWM27445.1 - 4.2e-12 46.4 0.1 8.3e-12 45.4 0.1 1.5 1 0 0 1 1 1 1 HIT domain ArsA_ATPase PF02374.10 EWM27451.1 - 3.3e-107 358.0 0.0 2.8e-105 351.7 0.0 2.0 1 1 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EWM27451.1 - 3.2e-14 52.7 0.0 8.1e-14 51.4 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EWM27451.1 - 2.5e-08 33.9 0.0 5.7e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 EWM27451.1 - 2.7e-06 26.7 0.1 2e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family PhoH PF02562.11 EWM27451.1 - 0.00027 20.2 0.0 0.00054 19.2 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein SRP54 PF00448.17 EWM27451.1 - 0.0014 18.1 0.1 0.0052 16.2 0.0 1.9 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain YhjQ PF06564.7 EWM27451.1 - 0.0037 16.6 0.0 0.0083 15.5 0.0 1.5 1 0 0 1 1 1 1 YhjQ protein AAA_19 PF13245.1 EWM27451.1 - 0.0038 16.9 0.1 0.013 15.2 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 EWM27451.1 - 0.012 15.0 0.0 0.056 12.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain MipZ PF09140.6 EWM27451.1 - 0.027 13.5 0.1 0.074 12.1 0.0 1.7 2 0 0 2 2 2 0 ATPase MipZ DUF2868 PF11067.3 EWM27451.1 - 0.04 13.0 0.0 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) NB-ARC PF00931.17 EWM27451.1 - 0.062 12.1 0.1 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain SNAP PF14938.1 EWM27452.1 - 3.7e-19 68.9 8.7 5.2e-19 68.4 6.0 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TOM20_plant PF06552.7 EWM27452.1 - 0.075 12.6 0.2 0.19 11.2 0.3 1.5 2 0 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 Peptidase_M20 PF01546.23 EWM27453.1 - 1.6e-24 86.4 0.0 2.7e-24 85.7 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EWM27453.1 - 3.7e-15 55.6 0.0 2.5e-14 52.9 0.0 2.2 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EWM27453.1 - 0.011 15.5 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 TruB_N PF01509.13 EWM27454.1 - 0.046 13.8 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 TruB family pseudouridylate synthase (N terminal domain) Sel1 PF08238.7 EWM27454.1 - 0.53 10.9 4.6 6.8 7.4 0.1 3.7 3 0 0 3 3 3 0 Sel1 repeat Hist_deacetyl PF00850.14 EWM27455.1 - 2.7e-54 184.5 0.0 5.9e-54 183.4 0.0 1.5 1 0 0 1 1 1 1 Histone deacetylase domain IBR PF01485.16 EWM27456.1 - 5.7e-16 58.1 49.2 5.1e-10 39.0 1.2 5.5 4 1 2 6 6 6 3 IBR domain RWD PF05773.17 EWM27456.1 - 2.2e-14 53.3 0.0 4.4e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.1 EWM27456.1 - 0.00012 21.8 8.4 0.00012 21.8 5.8 5.2 5 2 0 5 5 5 2 Ring finger domain zf-C3HC4_2 PF13923.1 EWM27456.1 - 0.00044 20.2 3.9 0.00044 20.2 2.7 5.6 6 0 0 6 6 6 1 Zinc finger, C3HC4 type (RING finger) Methyltransf_16 PF10294.4 EWM27458.1 - 1.6e-26 92.7 0.0 1.1e-25 90.1 0.0 2.3 3 1 0 3 3 3 1 Putative methyltransferase Methyltransf_23 PF13489.1 EWM27458.1 - 0.0032 17.1 0.0 0.0058 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM27458.1 - 0.0046 17.5 0.0 0.01 16.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EWM27458.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain APH PF01636.18 EWM27460.1 - 2.6e-10 40.4 2.5 3.7e-10 39.9 1.5 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Aa_trans PF01490.13 EWM27461.1 - 7.1e-08 31.3 2.0 8.8e-08 31.0 1.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EWM27461.1 - 0.033 12.9 0.5 0.04 12.7 0.4 1.0 1 0 0 1 1 1 0 Tryptophan/tyrosine permease family ABC2_membrane PF01061.19 EWM27462.1 - 3.4e-27 94.9 22.0 3.4e-27 94.9 15.2 2.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 EWM27462.1 - 3.7e-26 92.0 0.1 6.5e-26 91.2 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EWM27462.1 - 3.9e-06 27.0 0.2 0.0018 18.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EWM27462.1 - 8e-05 22.0 0.3 0.00017 21.0 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EWM27462.1 - 8e-05 22.1 0.2 0.0061 15.9 0.1 2.4 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EWM27462.1 - 0.0027 16.8 0.1 0.007 15.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EWM27462.1 - 0.0054 16.7 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 EWM27462.1 - 0.0091 15.2 1.5 1.2 8.3 0.1 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain NACHT PF05729.7 EWM27462.1 - 0.019 14.6 0.0 0.044 13.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.1 EWM27462.1 - 0.031 14.3 0.0 0.084 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EWM27462.1 - 0.038 14.2 0.0 0.072 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EWM27462.1 - 0.053 14.3 0.1 0.12 13.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 EWM27462.1 - 0.055 12.1 0.0 0.081 11.5 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein MobB PF03205.9 EWM27462.1 - 0.082 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RecA PF00154.16 EWM27462.1 - 0.095 11.7 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein ArgK PF03308.11 EWM27462.1 - 0.11 11.2 0.1 0.18 10.5 0.1 1.2 1 0 0 1 1 1 0 ArgK protein AAA_23 PF13476.1 EWM27462.1 - 0.13 12.6 0.0 0.22 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EWM27462.1 - 0.18 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain hEGF PF12661.2 EWM27462.1 - 1.2 9.3 4.5 3.7 7.8 3.1 1.9 1 0 0 1 1 1 0 Human growth factor-like EGF DUF3481 PF11980.3 EWM27462.1 - 1.5 8.7 4.9 0.23 11.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3481) Mito_carr PF00153.22 EWM27463.1 - 3.7e-64 212.4 2.9 4.3e-22 77.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Gp_dh_C PF02800.15 EWM27464.1 - 1e-72 242.7 0.0 1.4e-72 242.3 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EWM27464.1 - 4.1e-37 127.4 0.1 9.3e-37 126.3 0.0 1.6 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DUF678 PF05077.7 EWM27465.1 - 3.9 7.5 9.4 1 9.3 0.7 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF678) DUF808 PF05661.7 EWM27468.1 - 0.11 11.3 0.0 0.23 10.2 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF808) ThiC PF01964.13 EWM27469.1 - 4.3e-194 644.8 0.0 5.2e-194 644.5 0.0 1.0 1 0 0 1 1 1 1 ThiC family ThiC-associated PF13667.1 EWM27469.1 - 3.6e-09 36.0 0.0 1e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 ThiC-associated domain TAF PF02969.12 EWM27470.1 - 8.2e-12 44.9 0.1 1.4e-11 44.1 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 EWM27470.1 - 1.1e-06 28.6 0.2 3.2e-06 27.1 0.1 1.7 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 EWM27470.1 - 0.00086 19.0 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CBFD_NFYB_HMF PF00808.18 EWM27470.1 - 0.0052 16.8 0.2 0.0087 16.0 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DOT1 PF08123.8 EWM27471.1 - 8.9e-11 41.4 0.0 3.1e-10 39.7 0.0 1.7 1 1 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 EWM27471.1 - 0.013 16.1 0.1 0.063 13.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain DUF4264 PF14084.1 EWM27471.1 - 0.1 11.9 0.0 0.34 10.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) FAE1_CUT1_RppA PF08392.7 EWM27472.1 - 1.6e-104 349.0 0.0 3.2e-87 292.2 0.0 2.1 2 0 0 2 2 2 2 FAE1/Type III polyketide synthase-like protein Chal_sti_synt_C PF02797.10 EWM27472.1 - 1e-11 44.9 0.0 2.2e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III_C PF08541.5 EWM27472.1 - 1.4e-11 44.2 0.0 1.6e-10 40.8 0.0 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Chal_sti_synt_N PF00195.14 EWM27472.1 - 2.7e-06 26.8 0.1 6.1e-06 25.6 0.1 1.5 1 1 1 2 2 2 1 Chalcone and stilbene synthases, N-terminal domain ACP_syn_III PF08545.5 EWM27472.1 - 8.5e-06 25.3 0.0 1.8e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FHA PF00498.21 EWM27474.1 - 5.5e-15 55.2 0.0 1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain PLAC8 PF04749.12 EWM27475.1 - 0.043 14.3 1.0 0.082 13.4 0.7 1.5 1 0 0 1 1 1 0 PLAC8 family DUF1546 PF07571.8 EWM27476.1 - 1.7e-11 44.0 0.0 2.6e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) DUF2264 PF10022.4 EWM27476.1 - 0.029 13.0 0.0 0.039 12.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2264) PP2C PF00481.16 EWM27477.1 - 2.7e-11 43.3 0.0 1e-10 41.4 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C ABC2_membrane PF01061.19 EWM27479.1 - 4.2e-33 114.2 21.3 6.5e-33 113.6 14.8 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EWM27479.1 - 2.2e-25 89.5 0.0 3.4e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 EWM27479.1 - 3.7e-06 26.2 14.3 3.7e-06 26.2 9.9 1.7 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.1 EWM27479.1 - 5.1e-05 23.3 0.0 0.0083 16.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EWM27479.1 - 9.9e-05 21.7 0.6 0.0002 20.8 0.4 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EWM27479.1 - 0.00078 19.8 0.2 0.0013 19.0 0.2 1.2 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EWM27479.1 - 0.00093 18.6 0.2 0.0034 16.8 0.1 1.8 2 0 0 2 2 2 1 AAA domain ABC2_membrane_2 PF12679.2 EWM27479.1 - 0.002 17.0 7.5 0.002 17.0 5.2 1.6 2 0 0 2 2 2 1 ABC-2 family transporter protein DUF258 PF03193.11 EWM27479.1 - 0.0041 16.3 0.1 0.0074 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 EWM27479.1 - 0.0067 15.6 0.1 0.36 10.0 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.1 EWM27479.1 - 0.075 12.9 0.2 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EWM27479.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Dynamin_N PF00350.18 EWM27479.1 - 0.19 11.5 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 Dynamin family ABC_ATPase PF09818.4 EWM27479.1 - 0.3 9.5 0.1 0.49 8.9 0.1 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class RRM_1 PF00076.17 EWM27480.1 - 3.9e-21 74.4 0.0 5.9e-21 73.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM27480.1 - 2.6e-17 62.5 0.0 4.4e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zinc_ribbon_5 PF13719.1 EWM27480.1 - 5.1e-11 41.9 0.3 8.6e-11 41.2 0.2 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EWM27480.1 - 9.7e-11 41.1 0.2 1.7e-10 40.4 0.1 1.4 1 0 0 1 1 1 1 zinc-ribbon domain RRM_5 PF13893.1 EWM27480.1 - 1.3e-09 37.7 0.0 2.5e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Elf1 PF05129.8 EWM27480.1 - 0.095 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Zn_ribbon_recom PF13408.1 EWM27480.1 - 1.7 8.9 3.9 18 5.6 0.5 2.4 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain efThoc1 PF11957.3 EWM27481.1 - 5.7e-35 120.7 0.0 7.5e-35 120.3 0.0 1.0 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor RabGAP-TBC PF00566.13 EWM27482.1 - 1.6e-11 44.1 0.0 5.7e-11 42.2 0.0 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Ribosomal_L28e PF01778.12 EWM27483.1 - 1.2e-30 106.3 2.5 2.4e-30 105.3 0.1 2.2 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 EWM27483.1 - 2e-23 82.3 17.3 2e-23 82.3 12.0 3.0 1 1 2 3 3 3 1 Mak16 protein C-terminal region Daxx PF03344.10 EWM27483.1 - 0.012 14.1 25.0 0.016 13.7 17.3 1.2 1 0 0 1 1 1 0 Daxx Family TFIIA PF03153.8 EWM27483.1 - 0.16 11.8 9.4 0.23 11.3 6.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CobT PF06213.7 EWM27483.1 - 0.31 10.1 20.1 0.19 10.8 12.9 1.5 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT efThoc1 PF11957.3 EWM27484.1 - 1.6e-15 56.5 0.0 1.3e-14 53.6 0.0 1.9 1 1 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Nitroreductase PF00881.19 EWM27486.1 - 4.3e-26 91.6 0.0 2.4e-25 89.2 0.0 1.9 1 1 0 1 1 1 1 Nitroreductase family Flavi_M PF01004.14 EWM27486.1 - 0.18 11.2 0.1 0.18 11.2 0.1 1.7 2 0 0 2 2 2 0 Flavivirus envelope glycoprotein M Ldh_1_N PF00056.18 EWM27487.1 - 8.6e-46 155.2 0.0 1.4e-45 154.5 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EWM27487.1 - 5.7e-44 149.9 0.1 8.5e-44 149.3 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EWM27487.1 - 0.00018 20.3 0.0 0.00029 19.6 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EWM27487.1 - 0.0002 21.6 0.1 0.0025 18.0 0.0 2.5 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EWM27487.1 - 0.015 14.4 1.9 0.047 12.7 0.3 2.5 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 EWM27487.1 - 0.026 14.5 0.2 0.1 12.6 0.0 2.1 2 0 0 2 2 2 0 NADH(P)-binding Lipase_GDSL_2 PF13472.1 EWM27491.1 - 1e-26 94.1 0.0 1.4e-26 93.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EWM27491.1 - 1e-24 87.6 0.0 1.3e-24 87.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase GMC_oxred_N PF00732.14 EWM27492.1 - 1.4e-78 264.0 0.0 2.2e-78 263.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EWM27492.1 - 6.4e-37 127.0 0.0 1.7e-36 125.6 0.0 1.8 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EWM27492.1 - 1e-05 24.6 0.8 2.4e-05 23.4 0.6 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EWM27492.1 - 8e-05 22.5 0.5 0.00019 21.4 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EWM27492.1 - 0.00043 19.2 3.9 0.0068 15.3 0.0 2.7 3 0 0 3 3 3 2 FAD binding domain Lycopene_cycl PF05834.7 EWM27492.1 - 0.0077 15.1 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Med29 PF11568.3 EWM27492.1 - 0.018 15.1 0.1 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 29 Mito_carr PF00153.22 EWM27493.1 - 1.4e-67 223.4 1.1 1.2e-25 88.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ammonium_transp PF00909.16 EWM27494.1 - 1.3e-114 382.8 34.0 1.5e-114 382.5 23.6 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family DUF456 PF04306.8 EWM27494.1 - 0.00067 19.7 12.7 0.00067 19.7 8.8 3.5 4 0 0 4 4 4 1 Protein of unknown function (DUF456) Gly-zipper_YMGG PF13441.1 EWM27494.1 - 0.32 10.5 7.1 1.3 8.5 4.9 2.2 1 0 0 1 1 1 0 YMGG-like Gly-zipper Rer1 PF03248.8 EWM27495.1 - 1.3e-64 216.9 9.4 1.8e-64 216.5 6.5 1.1 1 0 0 1 1 1 1 Rer1 family DUF2208 PF09973.4 EWM27495.1 - 5.5 6.1 5.9 0.71 9.0 0.7 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) DUF1014 PF06244.7 EWM27496.1 - 2.5e-25 89.0 26.1 2.8e-24 85.6 13.7 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF1014) HMG_box PF00505.14 EWM27496.1 - 0.0038 17.4 1.0 0.0038 17.4 0.7 2.9 4 0 0 4 4 4 1 HMG (high mobility group) box Noelin-1 PF12308.3 EWM27496.1 - 0.0091 15.7 1.6 0.016 15.0 1.1 1.4 1 0 0 1 1 1 1 Neurogenesis glycoprotein PTPlike_phytase PF14566.1 EWM27496.1 - 0.63 10.0 3.0 1.5 8.8 2.1 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate Thioredoxin_4 PF13462.1 EWM27496.1 - 1.3 9.0 10.9 0.16 12.0 4.6 1.7 2 0 0 2 2 2 0 Thioredoxin DUF4140 PF13600.1 EWM27496.1 - 5.6 7.4 17.4 1.1 9.6 4.0 2.7 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Thioredoxin PF00085.15 EWM27497.1 - 0.0051 16.4 0.0 0.019 14.6 0.0 1.9 2 1 0 2 2 2 1 Thioredoxin Cellulase-like PF12876.2 EWM27497.1 - 0.1 13.0 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 Sugar-binding cellulase-like AAA_25 PF13481.1 EWM27499.1 - 0.00013 21.4 0.1 0.017 14.5 0.1 2.1 2 0 0 2 2 2 2 AAA domain RecA PF00154.16 EWM27499.1 - 0.0018 17.3 0.0 0.0029 16.7 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein DUF393 PF04134.7 EWM27501.1 - 3.9e-20 73.0 0.0 5.9e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF393 ATP-synt_ab PF00006.20 EWM27503.1 - 4.2e-37 127.7 0.0 1.4e-36 126.0 0.0 1.8 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.1 EWM27503.1 - 7.3e-07 28.7 0.0 2.8e-06 26.8 0.0 1.9 1 1 1 2 2 2 1 AAA domain ABC_tran PF00005.22 EWM27503.1 - 0.0014 18.8 0.0 0.0068 16.7 0.0 2.0 2 0 0 2 2 2 1 ABC transporter KaiC PF06745.8 EWM27503.1 - 0.0046 16.0 0.0 0.0078 15.3 0.0 1.3 1 0 0 1 1 1 1 KaiC HAS-barrel PF09378.5 EWM27503.1 - 0.013 15.4 0.0 0.03 14.1 0.0 1.6 1 0 0 1 1 1 0 HAS barrel domain AAA_16 PF13191.1 EWM27503.1 - 0.015 15.3 0.1 0.073 13.0 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain ArgK PF03308.11 EWM27503.1 - 0.021 13.6 0.1 0.043 12.5 0.0 1.4 1 0 0 1 1 1 0 ArgK protein AAA_17 PF13207.1 EWM27503.1 - 0.024 15.4 0.2 0.38 11.5 0.0 2.5 2 1 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EWM27503.1 - 0.029 14.0 0.0 0.072 12.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 EWM27503.1 - 0.031 13.1 0.0 0.069 11.9 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain MMR_HSR1 PF01926.18 EWM27503.1 - 0.043 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_10 PF12846.2 EWM27503.1 - 0.053 12.9 0.1 0.15 11.5 0.0 1.8 2 1 0 2 2 2 0 AAA-like domain AAA_22 PF13401.1 EWM27503.1 - 0.068 13.3 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EWM27503.1 - 0.074 12.8 1.0 0.36 10.6 0.1 2.7 3 0 0 3 3 3 0 Part of AAA domain RNA_helicase PF00910.17 EWM27503.1 - 0.18 11.9 0.0 3.9 7.6 0.0 2.3 2 0 0 2 2 2 0 RNA helicase Ribosomal_L15e PF00827.12 EWM27504.1 - 3.4e-89 297.4 9.6 3.9e-89 297.2 6.6 1.0 1 0 0 1 1 1 1 Ribosomal L15 UTP15_C PF09384.5 EWM27505.1 - 1.1e-42 145.2 0.0 1.5e-42 144.8 0.0 1.2 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 EWM27505.1 - 8.7e-25 85.6 10.5 2.7e-07 30.2 0.0 6.7 6 1 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 EWM27505.1 - 0.022 12.9 2.0 4.5 5.2 0.1 3.1 2 1 0 3 3 3 0 Nucleoporin Nup120/160 PQQ_3 PF13570.1 EWM27505.1 - 0.31 11.3 10.5 2.1 8.7 0.1 5.1 6 1 1 7 7 7 0 PQQ-like domain AAA_26 PF13500.1 EWM27506.1 - 7.2e-18 64.9 0.0 1.6e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 EWM27506.1 - 0.0018 17.7 0.0 0.0036 16.7 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Abhydrolase_5 PF12695.2 EWM27507.1 - 3e-22 78.9 0.0 3.8e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EWM27507.1 - 4.7e-11 42.9 0.3 7.2e-05 22.7 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EWM27507.1 - 4.9e-06 25.9 0.0 5.3e-05 22.5 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EWM27507.1 - 6.8e-05 22.5 0.0 0.035 13.6 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EWM27507.1 - 0.00045 19.9 0.0 0.00096 18.9 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 EWM27507.1 - 0.018 14.4 0.0 0.052 12.9 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase LIP PF03583.9 EWM27507.1 - 0.066 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Secretory lipase DLH PF01738.13 EWM27507.1 - 0.07 12.3 0.0 0.52 9.5 0.0 1.9 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 EWM27507.1 - 0.073 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF818 PF05677.7 EWM27507.1 - 0.14 10.8 0.0 0.23 10.1 0.0 1.3 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) WD40 PF00400.27 EWM27509.1 - 5.5e-87 282.8 13.3 5.4e-11 41.9 0.0 8.5 8 1 0 8 8 8 8 WD domain, G-beta repeat NLE PF08154.7 EWM27509.1 - 4.9e-11 42.4 0.0 8e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 EWM27509.1 - 5.8e-09 34.6 2.7 0.0099 14.0 0.2 4.1 2 2 2 4 4 4 4 Nucleoporin Nup120/160 PD40 PF07676.7 EWM27509.1 - 2e-06 27.3 1.0 3.2 7.5 0.0 4.7 4 0 0 4 4 4 3 WD40-like Beta Propeller Repeat eIF2A PF08662.6 EWM27509.1 - 4.5e-06 26.5 0.1 0.017 14.8 0.0 3.6 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 EWM27509.1 - 0.00017 20.8 0.2 2.5 7.1 0.0 4.1 2 2 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 EWM27509.1 - 0.0033 16.2 0.1 0.75 8.4 0.0 3.0 2 1 1 3 3 3 1 Nup133 N terminal like Proteasome_A_N PF10584.4 EWM27509.1 - 0.17 11.2 4.6 22 4.5 0.1 3.6 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Glyco_hydro_3 PF00933.16 EWM27510.1 - 2.3e-71 240.2 0.0 3e-71 239.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EWM27510.1 - 6.6e-33 114.1 0.0 1.5e-32 112.9 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Med26 PF08711.6 EWM27511.1 - 0.0016 17.8 0.0 0.0057 16.1 0.0 2.0 1 1 0 1 1 1 1 TFIIS helical bundle-like domain Lipase_3 PF01764.20 EWM27512.1 - 1.6e-19 69.9 0.0 2.7e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PE-PPE PF08237.6 EWM27512.1 - 0.014 14.7 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain FSH1 PF03959.8 EWM27512.1 - 0.053 12.9 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) RRM_6 PF14259.1 EWM27514.1 - 0.012 15.5 0.0 8.4 6.4 0.0 3.1 2 1 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM27514.1 - 0.017 14.9 0.0 0.21 11.4 0.0 2.5 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mtc PF03820.12 EWM27515.1 - 4.1e-59 199.7 0.0 5.1e-59 199.4 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Hist_deacetyl PF00850.14 EWM27517.1 - 6.9e-61 206.2 0.0 9.9e-61 205.7 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Hen1_L PF12623.2 EWM27517.1 - 0.072 11.8 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 RNA repair, ligase-Pnkp-associating, region of Hen1 Cupin_4 PF08007.7 EWM27518.1 - 3.8e-37 128.2 0.0 1.3e-30 106.7 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein Cupin_8 PF13621.1 EWM27518.1 - 3.9e-10 39.6 0.0 5.5e-08 32.6 0.0 2.5 2 1 0 2 2 2 1 Cupin-like domain Cupin_2 PF07883.6 EWM27518.1 - 0.0059 16.0 0.0 0.026 14.0 0.0 2.0 2 0 0 2 2 2 1 Cupin domain JmjC PF02373.17 EWM27518.1 - 0.05 13.8 0.0 0.23 11.7 0.0 2.0 1 1 0 1 1 1 0 JmjC domain, hydroxylase ARD PF03079.9 EWM27518.1 - 0.16 11.9 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 ARD/ARD' family KCNQC3-Ank-G_bd PF11956.3 EWM27519.1 - 0.06 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Ankyrin-G binding motif of KCNQ2-3 Presenilin PF01080.12 EWM27520.1 - 1.1e-73 248.3 2.1 3.5e-42 144.6 1.0 2.0 2 0 0 2 2 2 2 Presenilin Shisa PF13908.1 EWM27520.1 - 0.25 11.5 1.4 0.98 9.5 0.2 2.4 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Zip PF02535.17 EWM27521.1 - 1.4e-28 99.8 0.6 1.2e-18 67.1 0.0 2.5 2 1 0 2 2 2 2 ZIP Zinc transporter DUF3353 PF11833.3 EWM27521.1 - 4.4 6.7 8.4 0.25 10.7 0.8 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3353) SNF2_N PF00176.18 EWM27522.1 - 1.7e-49 168.2 0.0 2.5e-49 167.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EWM27522.1 - 3.8e-13 49.0 0.0 7.6e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3535 PF12054.3 EWM27522.1 - 0.0012 17.6 0.0 0.0023 16.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3535) HEAT PF02985.17 EWM27522.1 - 0.0024 17.8 0.1 0.23 11.6 0.0 3.3 2 0 0 2 2 2 1 HEAT repeat HEAT_EZ PF13513.1 EWM27522.1 - 0.03 14.7 0.6 29 5.3 0.0 4.4 3 0 0 3 3 3 0 HEAT-like repeat ResIII PF04851.10 EWM27522.1 - 0.056 13.2 0.0 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Endonuclease_NS PF01223.18 EWM27523.1 - 9.2e-51 172.4 0.0 1.1e-50 172.1 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease PCI PF01399.22 EWM27525.1 - 6.8e-14 52.0 0.0 1.5e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 PCI domain eIF3_N PF09440.5 EWM27525.1 - 5.2e-06 26.6 2.2 5.2e-06 26.6 1.5 2.0 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI_Csn8 PF10075.4 EWM27525.1 - 0.042 13.6 0.0 0.12 12.1 0.0 1.6 1 1 0 1 1 1 0 COP9 signalosome, subunit CSN8 TPR_14 PF13428.1 EWM27525.1 - 1 10.1 4.3 0.88 10.3 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat OTU PF02338.14 EWM27526.1 - 1.3e-16 61.2 0.1 9.1e-16 58.5 0.0 2.5 2 1 0 2 2 2 1 OTU-like cysteine protease Lipase_3 PF01764.20 EWM27527.1 - 4.8e-26 91.0 0.0 7.7e-26 90.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) C2 PF00168.25 EWM27527.1 - 1.4e-11 44.0 0.0 2.2e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 C2 domain DUF2974 PF11187.3 EWM27527.1 - 0.018 14.4 0.0 0.9 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) BRCT PF00533.21 EWM27528.1 - 8.2e-10 38.6 0.0 0.0014 18.7 0.0 2.4 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain DUF605 PF04652.11 EWM27528.1 - 0.011 15.1 1.3 0.017 14.5 0.9 1.3 1 0 0 1 1 1 0 Vta1 like FAD_binding_2 PF00890.19 EWM27529.1 - 3.5e-79 266.6 2.7 6e-79 265.8 1.9 1.4 1 0 0 1 1 1 1 FAD binding domain ApbE PF02424.10 EWM27529.1 - 4.4e-49 167.0 0.4 2e-33 115.7 0.0 2.3 2 0 0 2 2 2 2 ApbE family NAD_binding_1 PF00175.16 EWM27529.1 - 3.4e-12 46.8 0.0 6.8e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_oxidored PF12831.2 EWM27529.1 - 2.4e-09 36.8 6.9 1.2e-08 34.4 4.9 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_6 PF00970.19 EWM27529.1 - 5.1e-09 36.1 0.0 1.1e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain DAO PF01266.19 EWM27529.1 - 7.2e-09 35.0 5.4 5.9e-07 28.7 3.7 2.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EWM27529.1 - 1.9e-08 34.4 0.9 9.9e-07 28.8 0.6 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EWM27529.1 - 4e-08 33.1 2.8 1.3e-06 28.2 1.0 3.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EWM27529.1 - 1.8e-06 27.1 5.2 4.3e-05 22.5 1.7 3.0 3 0 0 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.9 EWM27529.1 - 0.00031 19.3 2.8 0.00031 19.3 2.0 2.5 3 0 0 3 3 3 1 HI0933-like protein AlaDh_PNT_C PF01262.16 EWM27529.1 - 0.00078 19.0 1.0 0.0021 17.6 0.4 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 EWM27529.1 - 0.0008 19.7 1.7 0.034 14.5 0.8 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EWM27529.1 - 0.0027 16.8 1.8 0.0032 16.5 0.2 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 EWM27529.1 - 0.0027 17.7 3.5 0.097 12.7 2.2 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EWM27529.1 - 0.014 14.4 1.2 0.023 13.7 0.8 1.3 1 0 0 1 1 1 0 FAD binding domain DXP_reductoisom PF02670.11 EWM27529.1 - 0.02 15.4 0.0 0.19 12.2 0.0 2.4 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lycopene_cycl PF05834.7 EWM27529.1 - 0.04 12.8 0.8 0.11 11.3 0.5 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Amino_oxidase PF01593.19 EWM27529.1 - 0.071 12.1 3.0 5.5 5.9 0.0 2.5 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase NAD_binding_6 PF08030.7 EWM27529.1 - 0.32 10.8 0.1 0.84 9.5 0.0 1.7 2 0 0 2 2 1 0 Ferric reductase NAD binding domain Trp_halogenase PF04820.9 EWM27529.1 - 0.4 9.2 1.2 0.64 8.5 0.8 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Helicase_C PF00271.26 EWM27530.1 - 1.6e-23 82.3 0.0 3.1e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EWM27530.1 - 0.017 15.0 0.0 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 Helicase C-terminal domain Tau95 PF09734.4 EWM27531.1 - 4.7e-33 114.8 0.0 8.1e-17 61.5 0.0 2.2 2 0 0 2 2 2 2 RNA polymerase III transcription factor (TF)IIIC subunit Sin_N PF04801.8 EWM27532.1 - 4.5e-57 193.7 0.0 8.4e-34 117.1 0.0 2.6 2 1 0 2 2 2 2 Sin-like protein conserved region Spc24 PF08286.6 EWM27534.1 - 4.3e-08 32.8 2.8 8.2e-08 31.9 0.1 2.1 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 Fe_dep_repr_C PF02742.10 EWM27534.1 - 0.0094 15.6 0.3 0.021 14.4 0.2 1.6 1 0 0 1 1 1 1 Iron dependent repressor, metal binding and dimerisation domain Laminin_II PF06009.7 EWM27534.1 - 0.011 15.4 3.6 0.013 15.2 0.6 2.0 1 1 1 2 2 2 0 Laminin Domain II Vps51 PF08700.6 EWM27534.1 - 0.15 11.9 1.7 10 6.0 0.1 2.3 2 0 0 2 2 2 0 Vps51/Vps67 DUF2894 PF11445.3 EWM27534.1 - 0.18 12.0 1.8 0.23 11.6 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) Cortex-I_coil PF09304.5 EWM27534.1 - 0.22 11.5 7.8 0.18 11.8 3.1 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil Uds1 PF15456.1 EWM27534.1 - 0.22 11.5 4.6 0.39 10.7 3.2 1.4 1 1 0 1 1 1 0 Up-regulated During Septation SlyX PF04102.7 EWM27534.1 - 0.26 11.6 2.3 0.71 10.2 0.4 2.1 2 0 0 2 2 2 0 SlyX CENP-F_leu_zip PF10473.4 EWM27534.1 - 0.3 10.9 9.7 0.76 9.6 6.1 1.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.10 EWM27534.1 - 1.5 8.3 5.0 4.8 6.7 1.0 2.4 2 0 0 2 2 2 0 Septum formation initiator IncA PF04156.9 EWM27534.1 - 3 7.3 8.8 24 4.4 6.1 2.0 1 1 0 1 1 1 0 IncA protein DUF4337 PF14235.1 EWM27534.1 - 3.5 7.4 8.2 1.2 8.9 3.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Syntaxin PF00804.20 EWM27534.1 - 4.4 7.5 7.2 67 3.7 5.0 2.3 1 1 0 1 1 1 0 Syntaxin DUF812 PF05667.6 EWM27534.1 - 5.9 5.2 11.7 14 3.9 8.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Aminotran_1_2 PF00155.16 EWM27535.1 - 1.8e-55 188.3 0.0 2.3e-55 187.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EWM27535.1 - 2.8e-07 29.1 0.0 5.4e-07 28.2 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Methyltransf_23 PF13489.1 EWM27536.1 - 3.4e-11 43.1 0.0 6e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM27536.1 - 6.6e-11 42.7 0.0 1.2e-10 41.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM27536.1 - 8.1e-08 32.5 0.1 3.9e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM27536.1 - 8.2e-08 32.6 0.0 1.7e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM27536.1 - 1.6e-07 31.7 0.0 3.1e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM27536.1 - 1.9e-07 30.7 0.0 2.9e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EWM27536.1 - 2.5e-06 27.1 0.0 3.6e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 EWM27536.1 - 0.00015 21.1 0.0 0.00037 19.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EWM27536.1 - 0.00019 20.5 0.0 0.00025 20.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EWM27536.1 - 0.00031 20.7 0.3 0.0014 18.6 0.2 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EWM27536.1 - 0.0013 17.9 0.0 0.0035 16.5 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_32 PF13679.1 EWM27536.1 - 0.0016 18.0 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EWM27536.1 - 0.0018 17.4 0.0 0.0062 15.6 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_PK PF05891.7 EWM27536.1 - 0.0078 15.5 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase RrnaAD PF00398.15 EWM27536.1 - 0.1 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase tRNA-synt_1d PF00750.14 EWM27537.1 - 1.2e-101 340.0 0.0 1.6e-101 339.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EWM27537.1 - 4.5e-31 107.2 0.1 1.2e-30 105.9 0.1 1.8 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 EWM27537.1 - 1.4e-23 83.2 0.0 4.4e-23 81.6 0.0 1.9 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.14 EWM27537.1 - 0.061 12.4 0.0 0.089 11.8 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EWM27537.1 - 0.16 10.5 0.1 0.27 9.8 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (M) RRM_1 PF00076.17 EWM27539.1 - 1.2e-41 140.1 0.0 1.2e-22 79.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM27539.1 - 2.2e-31 107.6 0.0 1.5e-15 56.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM27539.1 - 1.9e-22 78.8 0.0 2.5e-10 40.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cation_efflux PF01545.16 EWM27540.1 - 1.7e-63 214.3 2.0 4.6e-63 212.9 1.4 1.6 1 1 0 1 1 1 1 Cation efflux family DUF3357 PF11837.3 EWM27540.1 - 0.0025 17.6 0.2 3 7.7 0.0 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3357) DUF1348 PF07080.6 EWM27541.1 - 2.2e-65 218.8 8.4 3e-65 218.3 5.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.2 EWM27541.1 - 4.1e-08 33.5 1.5 7.1e-08 32.7 1.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EWM27541.1 - 4.2e-05 23.7 0.3 7.6e-05 22.8 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_4 PF13577.1 EWM27541.1 - 0.057 13.3 0.6 0.11 12.4 0.4 1.5 1 1 0 1 1 1 0 SnoaL-like domain SnoaL PF07366.7 EWM27541.1 - 0.086 12.4 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EWM27542.1 - 0.00061 20.1 0.1 0.00096 19.5 0.0 1.5 1 1 0 1 1 1 1 SnoaL-like domain Ank_2 PF12796.2 EWM27543.1 - 1e-07 32.1 0.0 1.2e-05 25.5 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EWM27543.1 - 6e-07 29.8 0.0 0.01 16.3 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EWM27543.1 - 0.0081 16.3 0.5 0.98 9.7 0.0 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM27543.1 - 0.0086 16.2 0.2 0.21 11.9 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.25 EWM27543.1 - 0.024 14.4 5.2 5.4 7.0 0.1 4.3 4 2 0 4 4 4 0 Ankyrin repeat DnaJ PF00226.26 EWM27544.1 - 1.1e-18 66.7 1.1 1.7e-18 66.0 0.8 1.3 1 0 0 1 1 1 1 DnaJ domain WD40 PF00400.27 EWM27547.1 - 6.8e-62 203.2 18.0 3e-08 33.2 0.2 11.9 11 1 0 11 11 11 10 WD domain, G-beta repeat tRNA_deacylase PF04414.7 EWM27547.1 - 2.9e-46 157.2 0.0 4.9e-46 156.5 0.0 1.4 1 0 0 1 1 1 1 D-aminoacyl-tRNA deacylase DUF2798 PF11391.3 EWM27547.1 - 0.11 12.2 0.1 0.28 10.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2798) IMS PF00817.15 EWM27548.1 - 1e-36 125.9 0.1 1.9e-36 125.0 0.1 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EWM27548.1 - 5.9e-18 65.0 0.0 1.6e-17 63.6 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT PF00533.21 EWM27548.1 - 6.2e-11 42.2 0.0 1.1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF4414 PF14377.1 EWM27548.1 - 9.1e-06 25.5 9.4 0.078 12.9 4.0 3.8 2 1 1 3 3 3 3 Domain of unknown function (DUF4414) IMS_HHH PF11798.3 EWM27548.1 - 0.0016 18.3 0.0 0.0069 16.3 0.0 2.1 2 0 0 2 2 2 1 IMS family HHH motif PTCB-BRCT PF12738.2 EWM27548.1 - 0.0074 16.1 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain U79_P34 PF03064.11 EWM27548.1 - 1.4 8.4 7.4 2.9 7.3 5.1 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Citrate_synt PF00285.16 EWM27549.1 - 7e-103 344.0 0.0 8.5e-103 343.8 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Acetyltransf_1 PF00583.19 EWM27550.1 - 1.3e-16 60.3 0.4 2.2e-16 59.6 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EWM27550.1 - 3.6e-07 30.3 0.0 6.1e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EWM27550.1 - 1.2e-06 28.6 0.1 2e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EWM27550.1 - 2.4e-05 23.9 0.1 4.8e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EWM27550.1 - 0.00019 21.3 0.1 0.00035 20.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EWM27550.1 - 0.0018 18.0 0.1 0.0045 16.8 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain UCH PF00443.24 EWM27551.1 - 7.1e-78 261.4 0.0 1.1e-77 260.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EWM27551.1 - 5.7e-20 71.5 0.0 1.4e-19 70.2 0.0 1.7 1 1 0 1 1 1 1 DUSP domain UCH_1 PF13423.1 EWM27551.1 - 2e-18 66.8 0.0 9.8e-09 35.0 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Zn-ribbon_8 PF09723.5 EWM27551.1 - 0.24 11.3 3.2 3.9 7.4 0.3 2.6 2 0 0 2 2 2 0 Zinc ribbon domain DZR PF12773.2 EWM27551.1 - 0.33 10.7 2.8 12 5.8 0.2 2.7 2 0 0 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.7 EWM27551.1 - 0.55 10.0 3.2 0.76 9.6 0.4 2.2 2 0 0 2 2 2 0 zinc-ribbons TF_Zn_Ribbon PF08271.7 EWM27551.1 - 0.59 9.5 3.3 0.21 10.9 0.1 2.0 2 0 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_2 PF13240.1 EWM27551.1 - 2.6 7.6 4.9 21 4.7 0.3 3.1 3 0 0 3 3 3 0 zinc-ribbon domain EF-hand_6 PF13405.1 EWM27553.1 - 2.4e-08 33.1 0.3 0.0012 18.5 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EWM27553.1 - 7e-08 31.2 2.3 0.00012 21.1 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EWM27553.1 - 1.7e-07 31.2 1.4 5.2e-07 29.7 0.9 1.8 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 EWM27553.1 - 1.2e-06 27.5 1.8 0.00027 20.1 0.2 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EWM27553.1 - 1e-05 25.0 0.8 0.0027 17.2 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EWM27553.1 - 0.058 13.4 2.4 0.53 10.3 1.7 2.3 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_7 PF13499.1 EWM27554.1 - 7.3e-10 38.8 4.6 4.8e-07 29.8 0.9 1.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EWM27554.1 - 2.3e-08 33.2 0.2 0.0011 18.6 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EWM27554.1 - 6.9e-08 31.2 2.3 0.00012 21.1 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 EWM27554.1 - 1.2e-06 27.5 1.8 0.00026 20.1 0.2 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EWM27554.1 - 1e-05 25.0 0.8 0.0027 17.2 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EWM27554.1 - 0.056 13.4 2.4 0.52 10.3 1.7 2.3 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Zip PF02535.17 EWM27555.1 - 0.15 11.0 4.8 0.14 11.1 0.3 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter PHD PF00628.24 EWM27556.1 - 1.2e-07 31.3 10.2 2e-07 30.5 7.1 1.4 1 0 0 1 1 1 1 PHD-finger zf-RING-like PF08746.6 EWM27556.1 - 0.027 14.4 5.0 0.051 13.5 3.5 1.5 1 0 0 1 1 1 0 RING-like domain Snurportin1 PF11538.3 EWM27556.1 - 3.7 7.3 9.7 9 6.1 6.7 1.6 1 0 0 1 1 1 0 Snurportin1 Kinesin PF00225.18 EWM27557.1 - 7.5e-113 376.6 0.9 7.5e-113 376.6 0.6 1.8 2 0 0 2 2 2 1 Kinesin motor domain PIF1 PF05970.9 EWM27557.1 - 0.0044 16.0 0.1 0.0086 15.0 0.1 1.4 1 0 0 1 1 1 1 PIF1-like helicase Herpes_UL32 PF06070.6 EWM27558.1 - 0.14 10.6 0.0 0.17 10.3 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 DUF2839 PF10999.3 EWM27558.1 - 4.5 7.3 6.2 5.7 7.0 4.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2839) DUF1295 PF06966.7 EWM27559.1 - 1.5e-43 148.7 1.2 1.8e-43 148.4 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EWM27559.1 - 0.0002 21.3 3.4 0.00038 20.5 0.0 2.7 2 2 1 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.9 EWM27559.1 - 0.0004 20.5 0.0 0.0016 18.6 0.0 2.0 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.11 EWM27559.1 - 0.09 12.5 0.0 0.09 12.5 0.0 2.3 2 1 0 3 3 3 0 3-oxo-5-alpha-steroid 4-dehydrogenase E1-E2_ATPase PF00122.15 EWM27560.1 - 7.6e-27 93.8 0.0 6.6e-26 90.7 0.0 2.3 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EWM27560.1 - 1.5e-16 61.4 0.0 8e-07 29.6 0.0 3.4 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase HAD PF12710.2 EWM27560.1 - 1e-14 55.1 0.1 2.6e-13 50.5 0.1 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 EWM27560.1 - 0.00014 21.7 0.1 0.00032 20.5 0.1 1.5 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase_like2 PF13246.1 EWM27560.1 - 0.00057 19.7 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Chorismate_synt PF01264.16 EWM27560.1 - 0.011 14.2 0.0 0.019 13.4 0.0 1.3 1 0 0 1 1 1 0 Chorismate synthase Cation_ATPase_N PF00690.21 EWM27560.1 - 0.022 14.2 1.8 0.032 13.6 0.0 2.2 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus ANF_receptor PF01094.23 EWM27561.1 - 4.4e-09 35.5 0.0 6.6e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region GTP_cyclohydro2 PF00925.15 EWM27561.1 - 0.035 13.3 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 GTP cyclohydrolase II S4 PF01479.20 EWM27562.1 - 0.017 14.5 0.2 0.15 11.5 0.2 2.2 1 1 1 2 2 2 0 S4 domain AATase PF07247.7 EWM27563.1 - 4.6e-07 28.7 0.0 9e-05 21.1 0.0 2.5 3 0 0 3 3 3 2 Alcohol acetyltransferase Condensation PF00668.15 EWM27563.1 - 6.5e-07 28.4 0.0 0.012 14.4 0.0 3.1 3 0 0 3 3 3 2 Condensation domain WES_acyltransf PF03007.11 EWM27563.1 - 4.6e-05 23.1 0.1 0.00038 20.1 0.0 2.2 2 0 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Radical_SAM PF04055.16 EWM27564.1 - 2.7e-05 24.3 0.0 5.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 EWM27564.1 - 0.001 19.0 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 EWM27564.1 - 0.0011 19.1 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Peptidase_M41 PF01434.13 EWM27565.1 - 1.2e-72 243.8 1.1 2e-72 243.0 0.7 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EWM27565.1 - 2.5e-43 147.4 0.0 4.2e-43 146.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EWM27565.1 - 1e-05 25.3 0.0 2.6e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EWM27565.1 - 9.2e-05 21.5 0.0 0.0011 18.0 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EWM27565.1 - 0.00018 21.6 0.2 0.016 15.3 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EWM27565.1 - 0.0002 21.3 0.6 0.0094 15.9 0.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain TIP49 PF06068.8 EWM27565.1 - 0.00039 19.2 0.0 0.00065 18.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 EWM27565.1 - 0.0006 19.5 0.1 0.0016 18.1 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EWM27565.1 - 0.0012 18.2 0.6 0.0026 17.1 0.1 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.1 EWM27565.1 - 0.0012 19.6 0.0 0.0028 18.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EWM27565.1 - 0.012 15.5 0.0 0.037 14.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.16 EWM27565.1 - 0.018 14.2 0.4 0.035 13.2 0.3 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EWM27565.1 - 0.024 14.0 1.7 0.096 12.0 0.3 2.2 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.1 EWM27565.1 - 0.039 13.8 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EWM27565.1 - 0.047 13.9 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Peptidase_M50B PF13398.1 EWM27565.1 - 0.056 12.8 1.2 0.078 12.3 0.0 1.7 2 0 0 2 2 2 0 Peptidase M50B-like AAA_14 PF13173.1 EWM27565.1 - 0.059 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AroM PF07302.6 EWM27565.1 - 0.076 12.3 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 AroM protein AAA_2 PF07724.9 EWM27565.1 - 0.1 12.4 0.0 0.8 9.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) DUF1624 PF07786.7 EWM27565.1 - 0.17 11.1 0.1 0.29 10.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1624) Pkinase PF00069.20 EWM27566.1 - 2e-38 132.0 0.0 3e-38 131.4 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM27566.1 - 3.6e-32 111.4 0.0 1.4e-27 96.4 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EWM27566.1 - 7.1e-05 22.6 0.3 0.00067 19.4 0.0 2.3 1 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EWM27566.1 - 0.014 14.7 0.1 0.024 13.9 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.6 EWM27566.1 - 0.031 13.0 0.0 0.048 12.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Arm PF00514.18 EWM27567.1 - 2.9e-10 39.5 0.7 1.3e-06 27.9 0.0 3.5 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EWM27567.1 - 0.0016 18.6 2.1 0.0021 18.2 0.3 2.0 2 0 0 2 2 2 1 HEAT repeats DUF1515 PF07439.6 EWM27569.1 - 0.00093 18.9 2.6 0.0093 15.7 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1515) DEAD_2 PF06733.10 EWM27570.1 - 4e-48 163.1 1.9 1.3e-47 161.4 0.8 2.0 2 0 0 2 2 2 1 DEAD_2 DUF1227 PF06777.6 EWM27570.1 - 5.9e-45 152.5 0.0 1.5e-44 151.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) Helicase_C_2 PF13307.1 EWM27570.1 - 2e-44 151.5 0.0 6.8e-44 149.7 0.0 1.9 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.10 EWM27570.1 - 1.6e-05 24.8 0.0 0.00089 19.1 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EWM27570.1 - 0.00054 19.5 0.1 0.11 12.0 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase SNF2_N PF00176.18 EWM27570.1 - 0.0033 16.2 0.0 0.016 14.0 0.0 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Tospo_nucleocap PF01533.11 EWM27570.1 - 0.075 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Tospovirus nucleocapsid protein MIP PF00230.15 EWM27571.1 - 2.8e-30 105.4 23.6 6.6e-16 58.4 5.1 2.3 2 0 0 2 2 2 2 Major intrinsic protein HSP90 PF00183.13 EWM27572.1 - 5.5e-173 576.1 19.7 8e-173 575.6 13.7 1.2 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 EWM27572.1 - 2.5e-10 40.1 1.3 4.6e-10 39.2 0.2 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EWM27572.1 - 3.3e-09 36.4 0.1 8.2e-09 35.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_C48 PF02902.14 EWM27573.1 - 1.1e-21 77.4 0.1 2e-09 37.4 0.0 3.4 3 0 0 3 3 3 3 Ulp1 protease family, C-terminal catalytic domain Myb_DNA-binding PF00249.26 EWM27574.1 - 1.5e-07 31.3 0.1 1.3e-06 28.3 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain CTP_synth_N PF06418.9 EWM27575.1 - 7.7e-94 313.8 0.0 1e-93 313.4 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EWM27575.1 - 1.2e-49 168.3 0.0 1.9e-49 167.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EWM27575.1 - 5e-08 32.6 0.3 2.4e-06 27.1 0.1 2.8 1 1 0 2 2 2 1 Peptidase C26 AA_permease_2 PF13520.1 EWM27576.1 - 1.2e-28 99.8 38.6 1.5e-28 99.5 26.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EWM27576.1 - 1.2e-24 86.5 34.8 1.4e-24 86.2 24.1 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1049 PF06305.6 EWM27576.1 - 6.8 6.2 10.4 1.4 8.4 0.2 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) HA2 PF04408.18 EWM27577.1 - 3.5e-17 62.3 0.0 7.3e-17 61.2 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EWM27577.1 - 1.2e-13 50.7 0.0 2.7e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EWM27577.1 - 3.2e-13 49.5 0.0 7.1e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EWM27577.1 - 8.4e-08 31.8 0.1 1.7e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EWM27577.1 - 4e-05 23.7 0.1 0.0001 22.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EWM27577.1 - 0.0005 20.0 0.4 0.061 13.3 0.2 3.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 EWM27577.1 - 0.0014 18.3 0.1 0.0046 16.6 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 EWM27577.1 - 0.0023 17.3 0.0 0.0092 15.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 EWM27577.1 - 0.0031 16.6 0.0 0.0057 15.7 0.0 1.3 1 0 0 1 1 1 1 KaiC FtsK_SpoIIIE PF01580.13 EWM27577.1 - 0.011 15.2 0.0 0.03 13.7 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.1 EWM27577.1 - 0.033 13.6 0.0 0.37 10.3 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_14 PF13173.1 EWM27577.1 - 0.033 14.0 0.0 0.26 11.1 0.0 2.2 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EWM27577.1 - 0.045 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter T2SE PF00437.15 EWM27577.1 - 0.046 12.6 0.0 0.081 11.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activat PF00158.21 EWM27577.1 - 0.066 12.6 0.1 0.76 9.2 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.17 EWM27577.1 - 0.068 12.0 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DAP3 PF10236.4 EWM27577.1 - 0.34 9.7 0.0 0.59 9.0 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 LETM1 PF07766.8 EWM27578.1 - 2.8e-92 308.5 0.4 2.8e-92 308.5 0.2 2.2 2 0 0 2 2 1 1 LETM1-like protein EF-hand_7 PF13499.1 EWM27578.1 - 6e-10 39.1 0.1 2e-09 37.4 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EWM27578.1 - 3.1e-07 29.2 0.0 0.013 14.7 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EWM27578.1 - 3.7e-05 23.2 0.1 0.066 13.1 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 EWM27578.1 - 0.00012 21.2 0.1 0.19 11.1 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EWM27578.1 - 0.00019 21.0 0.0 0.00042 19.8 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair Fe_hyd_lg_C PF02906.9 EWM27578.1 - 0.02 14.1 3.4 0.11 11.7 0.2 2.4 1 1 1 2 2 2 0 Iron only hydrogenase large subunit, C-terminal domain SPARC_Ca_bdg PF10591.4 EWM27578.1 - 0.057 13.4 0.2 0.057 13.4 0.1 2.5 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF4248 PF14053.1 EWM27578.1 - 0.084 12.4 0.1 0.48 10.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) DUF4557 PF15101.1 EWM27578.1 - 2.3 8.0 6.0 5.2 6.8 4.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Ycf1 PF05758.7 EWM27578.1 - 2.5 5.7 7.8 4 5.0 5.4 1.3 1 0 0 1 1 1 0 Ycf1 Ribosomal_L25p PF01386.14 EWM27579.1 - 5.8e-13 48.7 0.0 9.9e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L25p family Ribosomal_TL5_C PF14693.1 EWM27579.1 - 1.2e-09 38.2 0.0 2.3e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein TL5, C-terminal domain Apc4 PF12896.2 EWM27580.1 - 9.8e-15 54.4 0.1 1.5e-14 53.7 0.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Apc4_WD40 PF12894.2 EWM27580.1 - 1e-11 44.1 0.0 1.6e-08 33.9 0.0 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.27 EWM27580.1 - 0.15 12.0 0.0 0.43 10.5 0.0 1.7 1 0 0 1 1 1 0 WD domain, G-beta repeat DUF4506 PF14958.1 EWM27581.1 - 7.5e-05 22.3 0.0 0.00015 21.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4506) ERCC4 PF02732.10 EWM27582.1 - 0.088 12.5 0.3 0.14 11.8 0.2 1.3 1 1 0 1 1 1 0 ERCC4 domain DUF59 PF01883.14 EWM27583.1 - 1.8e-11 43.8 0.2 3.9e-11 42.7 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF59 B56 PF01603.15 EWM27585.1 - 8.5e-10 37.8 0.0 2e-09 36.5 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DSPc PF00782.15 EWM27586.1 - 3.5e-23 81.6 0.1 5.2e-23 81.0 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CTP_transf_2 PF01467.21 EWM27586.1 - 5.1e-06 26.6 0.0 1.3e-05 25.2 0.0 1.7 2 0 0 2 2 2 1 Cytidylyltransferase Y_phosphatase PF00102.22 EWM27586.1 - 3.8e-05 23.1 0.1 9e-05 21.9 0.0 1.5 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EWM27586.1 - 0.018 15.2 0.0 0.046 13.9 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 EWM27586.1 - 0.026 13.9 0.0 0.043 13.1 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family SBF PF01758.11 EWM27587.1 - 3.8e-36 124.2 17.6 9e-36 123.0 12.2 1.6 1 0 0 1 1 1 1 Sodium Bile acid symporter family DUF4137 PF13593.1 EWM27587.1 - 7.8e-18 64.6 24.8 1.1e-17 64.0 17.2 1.3 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Adeno_E3 PF06040.6 EWM27587.1 - 4.4 7.2 5.6 14 5.6 0.9 2.5 1 1 1 2 2 2 0 Adenovirus E3 protein zf-DHHC PF01529.15 EWM27588.1 - 1.5e-39 135.2 8.0 5.6e-39 133.3 5.6 1.9 1 1 0 1 1 1 1 DHHC palmitoyltransferase UCR_UQCRX_QCR9 PF05365.7 EWM27589.1 - 4.5e-13 48.6 1.5 7.8e-13 47.8 1.0 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF456 PF04306.8 EWM27589.1 - 0.023 14.7 0.2 0.028 14.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Lactamase_B_2 PF12706.2 EWM27590.1 - 5.3e-14 52.2 0.2 7.6e-14 51.6 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EWM27590.1 - 0.0016 18.1 0.4 0.0043 16.7 0.1 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Terminase_4 PF05119.7 EWM27590.1 - 0.03 14.4 0.0 0.063 13.4 0.0 1.4 1 0 0 1 1 1 0 Phage terminase, small subunit Mito_carr PF00153.22 EWM27591.1 - 1.5e-68 226.5 0.0 4e-24 84.1 0.2 4.0 3 2 0 3 3 3 3 Mitochondrial carrier protein Mad3_BUB1_II PF08171.6 EWM27591.1 - 0.02 14.7 0.1 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Mad3/BUB1 homology region 2 DUF780 PF05611.6 EWM27591.1 - 0.13 13.0 1.5 1.3 9.7 0.5 2.4 2 0 0 2 2 2 0 Caenorhabditis elegans protein of unknown function (DUF780) EF-hand_1 PF00036.27 EWM27592.1 - 3.7e-07 28.9 1.8 0.036 13.3 0.0 3.7 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.1 EWM27592.1 - 2.7e-06 26.8 0.3 0.33 10.9 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 EWM27592.1 - 4.4e-05 23.5 0.1 0.31 11.2 0.0 2.9 2 1 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 EWM27592.1 - 7.9e-05 21.8 0.6 0.94 8.9 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 EWM27592.1 - 0.00035 20.1 0.2 0.13 11.9 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair Acyltransferase PF01553.16 EWM27593.1 - 8.2e-15 54.4 0.0 1.3e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF1673 PF07895.6 EWM27593.1 - 0.17 11.3 0.9 0.28 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) XRN_N PF03159.13 EWM27594.1 - 1.6e-94 315.7 0.1 2.5e-94 315.1 0.1 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus NUDIX PF00293.23 EWM27595.1 - 1.9e-23 82.5 0.0 2.8e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain zf-RING_2 PF13639.1 EWM27596.1 - 3.4e-14 52.3 5.2 3.4e-14 52.3 3.6 3.2 2 1 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EWM27596.1 - 4.6e-09 36.2 1.1 4.6e-09 36.2 0.8 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EWM27596.1 - 3.6e-08 33.2 4.3 3.6e-08 33.2 3.0 3.9 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EWM27596.1 - 5.8e-08 32.2 2.8 5.8e-08 32.2 1.9 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EWM27596.1 - 2.6e-07 30.1 5.0 2.6e-07 30.1 3.5 3.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EWM27596.1 - 6.5e-07 28.9 3.4 6.5e-07 28.9 2.4 3.5 4 0 0 4 4 4 1 zinc-RING finger domain RINGv PF12906.2 EWM27596.1 - 0.034 14.1 4.3 0.034 14.1 3.0 2.4 3 1 0 3 3 3 0 RING-variant domain zf-Apc11 PF12861.2 EWM27596.1 - 0.1 12.4 5.8 0.069 13.0 1.2 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger GST_N_3 PF13417.1 EWM27597.1 - 1.4e-14 54.0 0.1 6.1e-13 48.7 0.0 3.0 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EWM27597.1 - 1.3e-09 37.8 0.1 3.6e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EWM27597.1 - 6.1e-07 29.2 0.6 1.9e-06 27.6 0.4 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EWM27597.1 - 0.0032 17.4 0.0 0.02 14.9 0.0 2.1 2 0 0 2 2 2 1 Glutaredoxin GST_C_3 PF14497.1 EWM27597.1 - 0.019 15.4 0.1 0.042 14.3 0.1 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EWM27597.1 - 0.036 14.0 0.0 0.083 12.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain 6PF2K PF01591.13 EWM27598.1 - 2.6e-53 180.3 0.0 3.9e-53 179.8 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EWM27598.1 - 4.3e-28 98.3 0.0 1.1e-27 97.1 0.0 1.7 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EWM27598.1 - 3.6e-06 26.9 0.3 6.4e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EWM27598.1 - 0.0022 18.7 0.1 0.0076 17.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 EWM27598.1 - 0.012 14.8 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 IstB_IS21 PF01695.12 EWM27598.1 - 0.15 11.4 0.1 0.37 10.1 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein NTPase_1 PF03266.10 EWM27598.1 - 0.21 11.2 0.0 0.4 10.3 0.0 1.4 1 0 0 1 1 1 0 NTPase Ribosomal_L18e PF00828.14 EWM27599.1 - 1.2e-23 83.9 0.2 1.2e-23 83.9 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 His_Phos_1 PF00300.17 EWM27600.1 - 5.1e-42 143.6 0.0 7e-42 143.2 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Exc PF07825.6 EWM27600.1 - 0.04 13.6 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 Excisionase-like protein Abhydrolase_6 PF12697.2 EWM27601.1 - 1.9e-09 37.7 0.9 2.9e-09 37.1 0.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM27601.1 - 1.3e-05 24.9 0.0 1.9e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EWM27601.1 - 0.0078 15.7 0.1 0.24 10.9 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold DNMT1-RFD PF12047.3 EWM27602.1 - 4e-08 33.0 0.1 9.8e-08 31.8 0.1 1.6 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain Prp19_bind PF06991.6 EWM27603.1 - 5.6e-64 216.0 31.5 5.6e-64 216.0 21.9 2.1 1 1 1 2 2 2 1 Splicing factor, Prp19-binding domain DUF2476 PF10630.4 EWM27603.1 - 1.9 8.3 5.7 0.84 9.4 2.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2476) Cupin_6 PF12852.2 EWM27604.1 - 0.02 14.5 0.0 0.048 13.2 0.0 1.7 1 0 0 1 1 1 0 Cupin Pho88 PF10032.4 EWM27606.1 - 3.5e-08 32.8 0.3 1.9e-06 27.2 0.2 2.2 1 1 0 1 1 1 1 Phosphate transport (Pho88) YadA_anchor PF03895.10 EWM27606.1 - 0.0076 16.2 0.0 0.021 14.7 0.0 1.8 1 0 0 1 1 1 1 YadA-like C-terminal region DUF566 PF04484.7 EWM27606.1 - 1.4 8.3 7.2 2.2 7.7 5.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) Glyco_hydro_1 PF00232.13 EWM27607.1 - 1.2e-163 544.5 0.2 1.6e-163 544.1 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 DUF3357 PF11837.3 EWM27607.1 - 0.075 12.8 1.4 0.078 12.8 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) DUF2248 PF10005.4 EWM27607.1 - 0.18 10.6 1.6 0.28 10.0 1.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2248) AA_permease_2 PF13520.1 EWM27608.1 - 1.9e-60 204.5 30.2 3.1e-60 203.9 20.8 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EWM27608.1 - 1.6e-46 158.6 33.8 2e-46 158.3 23.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.1 EWM27608.1 - 2.4e-06 27.2 5.0 2.4e-06 27.2 3.5 3.2 3 0 0 3 3 3 1 C-terminus of AA_permease UCH PF00443.24 EWM27609.1 - 8.5e-49 166.0 0.0 1.4e-48 165.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EWM27609.1 - 8.3e-21 74.6 0.0 1.5e-14 54.1 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PsbQ PF05757.6 EWM27610.1 - 0.0026 17.2 1.2 0.019 14.4 0.3 2.3 1 1 0 2 2 2 1 Oxygen evolving enhancer protein 3 (PsbQ) UCR_Fe-S_N PF10399.4 EWM27610.1 - 0.0051 15.9 0.1 0.0051 15.9 0.1 1.7 2 0 0 2 2 2 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF3667 PF12412.3 EWM27612.1 - 0.013 14.7 0.1 0.028 13.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3667) UBA_4 PF14555.1 EWM27613.1 - 2.1e-07 30.3 0.2 3.6e-07 29.6 0.2 1.3 1 0 0 1 1 1 1 UBA-like domain DUF3418 PF11898.3 EWM27613.1 - 0.053 11.9 0.2 0.069 11.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) Rad51 PF08423.6 EWM27615.1 - 1.3e-130 433.8 0.1 1.9e-130 433.3 0.1 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EWM27615.1 - 2.2e-14 53.3 0.0 3.2e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 EWM27615.1 - 3.3e-14 52.6 0.1 4.9e-14 52.1 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 EWM27615.1 - 2.1e-10 40.1 0.2 6e-10 38.6 0.0 1.8 2 0 0 2 2 2 1 KaiC HHH_5 PF14520.1 EWM27615.1 - 1e-07 32.0 0.1 6.4e-07 29.4 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain PAXNEB PF05625.6 EWM27615.1 - 0.018 13.8 0.1 0.035 12.9 0.1 1.4 1 0 0 1 1 1 0 PAXNEB protein HhH-GPD PF00730.20 EWM27615.1 - 0.039 14.2 0.0 0.063 13.5 0.0 1.4 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein AAA_22 PF13401.1 EWM27615.1 - 0.044 13.9 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain HHH_2 PF12826.2 EWM27615.1 - 0.055 13.3 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH PF00633.18 EWM27615.1 - 0.077 12.7 0.0 0.25 11.1 0.0 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix motif DnaB_C PF03796.10 EWM27615.1 - 0.088 11.6 0.1 1.2 7.9 0.0 2.3 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain OppC_N PF12911.2 EWM27616.1 - 1.4 8.3 4.2 18 4.8 0.0 2.3 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Methyltransf_11 PF08241.7 EWM27618.1 - 2.4e-20 72.7 0.0 1.3e-19 70.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM27618.1 - 6.1e-15 55.3 0.0 1.6e-14 53.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM27618.1 - 2.8e-13 49.6 0.0 4.7e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EWM27618.1 - 8.6e-11 41.4 0.0 1.5e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 EWM27618.1 - 2.6e-10 40.5 0.0 1.2e-09 38.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EWM27618.1 - 1.5e-09 37.2 0.0 2.6e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EWM27618.1 - 3.7e-07 30.5 0.0 1.4e-06 28.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM27618.1 - 1.4e-06 28.8 0.0 1.4e-05 25.5 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM27618.1 - 0.00054 19.9 0.1 0.0017 18.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Sterol_MT_C PF08498.5 EWM27618.1 - 0.00067 19.5 0.1 0.002 18.0 0.0 1.8 1 1 0 1 1 1 1 Sterol methyltransferase C-terminal DUF498 PF04430.9 EWM27619.1 - 5e-29 100.0 0.0 2.7e-28 97.7 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF498/DUF598) Aa_trans PF01490.13 EWM27620.1 - 2.3e-60 204.2 21.0 2.8e-60 203.9 14.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Vma12 PF11712.3 EWM27620.1 - 9.9 5.8 5.6 0.94 9.1 0.3 1.9 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Ldh_2 PF02615.9 EWM27621.1 - 1.6e-56 191.4 0.1 2.8e-56 190.6 0.1 1.3 2 0 0 2 2 2 1 Malate/L-lactate dehydrogenase Acetyltransf_1 PF00583.19 EWM27621.1 - 0.0089 16.0 0.3 0.95 9.5 0.0 2.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.1 EWM27621.1 - 0.049 13.5 0.4 0.35 10.7 0.1 2.4 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase PLC-beta_C PF08703.5 EWM27622.1 - 0.15 11.7 3.3 0.28 10.8 2.3 1.4 1 0 0 1 1 1 0 PLC-beta C terminal DUF1014 PF06244.7 EWM27622.1 - 0.52 10.5 5.9 0.83 9.8 3.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1014) SMC_N PF02463.14 EWM27623.1 - 1.1e-07 31.2 0.0 1.9e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 EWM27623.1 - 7.5e-06 25.7 0.0 2e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EWM27623.1 - 0.00032 21.0 0.0 0.00032 21.0 0.0 3.0 3 1 0 3 3 3 1 AAA domain ABC_tran PF00005.22 EWM27623.1 - 0.021 15.1 0.5 0.21 11.8 0.4 2.8 1 1 0 1 1 1 0 ABC transporter Cluap1 PF10234.4 EWM27623.1 - 0.075 12.2 14.6 0.22 10.7 10.1 1.8 1 0 0 1 1 1 0 Clusterin-associated protein-1 V_ATPase_I PF01496.14 EWM27623.1 - 5.7 4.6 15.9 0.27 9.0 6.6 1.8 2 1 0 2 2 2 0 V-type ATPase 116kDa subunit family Pyrid_oxidase_2 PF13883.1 EWM27625.1 - 1.4e-40 138.8 0.0 1.8e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Spore_coat_CotO PF14153.1 EWM27626.1 - 5.3e-05 22.7 4.8 6.7e-05 22.3 3.3 1.3 1 0 0 1 1 1 1 Spore coat protein CotO Nop14 PF04147.7 EWM27626.1 - 0.0048 14.9 22.3 0.006 14.5 15.5 1.1 1 0 0 1 1 1 1 Nop14-like family SAPS PF04499.10 EWM27626.1 - 0.0052 15.4 2.3 0.0072 15.0 1.6 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein eIF-3c_N PF05470.7 EWM27626.1 - 0.031 12.3 1.2 0.03 12.4 0.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Ycf1 PF05758.7 EWM27626.1 - 0.068 10.8 6.5 0.077 10.7 4.5 1.0 1 0 0 1 1 1 0 Ycf1 CDC45 PF02724.9 EWM27626.1 - 0.15 10.1 14.1 0.21 9.6 9.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.6 EWM27626.1 - 0.26 9.0 3.4 0.41 8.4 2.3 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RRN3 PF05327.6 EWM27626.1 - 0.3 9.1 9.7 0.38 8.8 6.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Tim54 PF11711.3 EWM27626.1 - 0.37 9.3 9.6 0.58 8.6 6.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SDA1 PF05285.7 EWM27626.1 - 0.38 9.9 21.4 0.6 9.3 14.8 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.5 EWM27626.1 - 0.45 9.5 18.5 0.58 9.1 12.8 1.2 1 0 0 1 1 1 0 BUD22 DUF2722 PF10846.3 EWM27626.1 - 1 8.3 4.1 1.3 7.9 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TEX19 PF15553.1 EWM27626.1 - 1.3 8.9 9.2 2.7 7.8 6.4 1.6 1 0 0 1 1 1 0 Testis-expressed protein 19 Vfa1 PF08432.5 EWM27626.1 - 1.3 9.0 13.1 2 8.3 9.1 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DDRGK PF09756.4 EWM27626.1 - 1.6 8.0 23.2 2.8 7.3 16.1 1.3 1 0 0 1 1 1 0 DDRGK domain Drc1-Sld2 PF11719.3 EWM27626.1 - 3 6.8 13.6 4.4 6.2 9.5 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein CENP-T PF15511.1 EWM27626.1 - 4.1 6.5 15.9 6 5.9 11.1 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF4246 PF14033.1 EWM27626.1 - 6 5.3 7.6 7.5 5.0 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) Zip PF02535.17 EWM27626.1 - 6.2 5.7 8.1 8.3 5.3 5.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2890 PF11081.3 EWM27626.1 - 8.3 6.4 22.5 14 5.6 15.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) VID27 PF08553.5 EWM27626.1 - 10 4.2 22.8 13 3.8 15.8 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Aa_trans PF01490.13 EWM27627.1 - 1.9e-61 207.8 6.8 2.4e-61 207.4 4.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein HA2 PF04408.18 EWM27628.1 - 1.1e-17 63.9 0.0 3.5e-17 62.2 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EWM27628.1 - 4.7e-14 52.0 0.1 1.3e-13 50.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EWM27628.1 - 8.3e-12 44.9 0.0 2.9e-11 43.2 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EWM27628.1 - 8.6e-08 31.8 0.0 2e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EWM27628.1 - 4.6e-05 23.5 0.9 9.4e-05 22.5 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EWM27628.1 - 0.0073 15.8 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SE PF00437.15 EWM27628.1 - 0.016 14.1 0.0 0.034 13.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EWM27628.1 - 0.019 14.4 0.0 0.16 11.4 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_14 PF13173.1 EWM27628.1 - 0.098 12.5 0.0 0.52 10.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain Endosulfine PF04667.12 EWM27630.1 - 0.0067 16.3 0.3 0.057 13.3 0.0 2.3 2 0 0 2 2 2 1 cAMP-regulated phosphoprotein/endosulfine conserved region BLOC1_2 PF10046.4 EWM27631.1 - 0.002 18.2 3.0 0.052 13.6 0.3 2.9 2 1 1 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATG16 PF08614.6 EWM27631.1 - 0.0021 17.9 2.6 1 9.1 0.0 2.3 2 0 0 2 2 2 2 Autophagy protein 16 (ATG16) Spc7 PF08317.6 EWM27631.1 - 0.014 14.0 4.1 0.024 13.3 2.7 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF2120 PF09893.4 EWM27631.1 - 0.24 11.3 2.0 8.2 6.3 0.5 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) APG6 PF04111.7 EWM27631.1 - 0.25 10.3 9.4 0.34 9.9 0.2 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 Spectrin PF00435.16 EWM27631.1 - 0.87 9.9 10.4 0.39 11.0 0.3 2.9 2 1 1 3 3 3 0 Spectrin repeat AAA_13 PF13166.1 EWM27631.1 - 1.5 7.1 8.4 12 4.2 5.9 1.8 1 1 0 1 1 1 0 AAA domain Cep57_CLD_2 PF14197.1 EWM27631.1 - 4.2 7.3 14.2 0.21 11.5 2.1 3.0 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 COG2 PF06148.6 EWM27631.1 - 9.2 6.1 7.7 37 4.1 0.4 3.2 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Abhydrolase_6 PF12697.2 EWM27632.1 - 7.1e-29 101.3 1.6 8.6e-29 101.0 1.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM27632.1 - 1.1e-08 34.9 0.0 2.2e-08 33.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EWM27632.1 - 0.032 13.7 0.0 1.5 8.3 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF4081 PF13312.1 EWM27632.1 - 0.04 13.8 0.0 10 6.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4081) Esterase PF00756.15 EWM27632.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Cupin_2 PF07883.6 EWM27633.1 - 0.00016 21.1 0.8 0.0004 19.8 0.5 1.7 1 1 1 2 2 2 1 Cupin domain Cupin_7 PF12973.2 EWM27633.1 - 0.0066 16.2 0.1 0.011 15.5 0.1 1.4 1 0 0 1 1 1 1 ChrR Cupin-like domain Ectoine_synth PF06339.7 EWM27633.1 - 0.083 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Ectoine synthase DUF4437 PF14499.1 EWM27633.1 - 0.086 11.7 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) OKR_DC_1 PF01276.15 EWM27635.1 - 1.9e-42 145.2 0.0 7.8e-42 143.2 0.0 1.9 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain OKR_DC_1_C PF03711.10 EWM27635.1 - 2.7e-08 33.9 0.0 5.2e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, C-terminal domain SLA_LP_auto_ag PF05889.8 EWM27635.1 - 2.9e-05 22.7 0.0 4.6e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Aminotran_1_2 PF00155.16 EWM27635.1 - 0.002 17.1 0.0 0.0051 15.8 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II MMR_HSR1 PF01926.18 EWM27636.1 - 9.4e-16 57.8 0.0 3.5e-15 55.9 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase NOG1 PF06858.9 EWM27636.1 - 5.3e-15 55.0 0.0 9.4e-15 54.2 0.0 1.4 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) FeoB_N PF02421.13 EWM27636.1 - 4.1e-08 32.6 0.3 9.5e-08 31.4 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Miro PF08477.8 EWM27636.1 - 9.1e-05 22.9 0.0 0.00019 21.8 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 EWM27636.1 - 0.0042 16.2 0.1 0.019 14.1 0.0 2.0 2 0 0 2 2 2 1 AIG1 family DUF258 PF03193.11 EWM27636.1 - 0.024 13.8 0.0 0.07 12.3 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EWM27636.1 - 0.064 13.0 0.2 15 5.4 0.1 2.5 1 1 1 2 2 2 0 Dynamin family CPT PF07931.7 EWM27636.1 - 0.11 12.0 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Ribosomal_S26e PF01283.14 EWM27637.1 - 1.4e-40 138.0 8.8 2.5e-40 137.2 6.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S26e FCH PF00611.18 EWM27639.1 - 2.2e-08 34.1 0.8 3.2e-07 30.4 0.2 3.0 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain Ras PF00071.17 EWM27640.1 - 1.3e-64 216.5 0.1 1.6e-64 216.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EWM27640.1 - 1.7e-21 76.8 0.0 2.6e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EWM27640.1 - 1.5e-16 60.1 0.1 1.9e-16 59.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EWM27640.1 - 8.7e-07 28.3 0.1 1.2e-06 27.8 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EWM27640.1 - 1.8e-05 24.2 0.1 4.5e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EWM27640.1 - 0.0026 17.6 0.0 0.0047 16.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EWM27640.1 - 0.0034 16.6 0.0 0.0048 16.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EWM27640.1 - 0.027 14.6 0.0 0.045 13.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain Topoisom_I_N PF02919.10 EWM27641.1 - 8.6e-79 263.7 0.0 8.6e-79 263.7 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EWM27641.1 - 3.5e-73 245.5 0.0 1e-72 244.0 0.0 1.8 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EWM27641.1 - 7.9e-34 115.1 0.4 2.1e-33 113.8 0.3 1.8 1 0 0 1 1 1 1 C-terminal topoisomerase domain Med9 PF07544.8 EWM27641.1 - 1.2 8.8 11.4 9.4 6.0 0.3 2.8 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Aminotran_5 PF00266.14 EWM27642.1 - 8.8e-93 310.9 0.0 1.1e-92 310.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EWM27642.1 - 3e-06 26.6 0.0 4.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EWM27642.1 - 0.00027 19.9 0.0 0.00038 19.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EWM27642.1 - 0.00036 19.6 0.0 0.00061 18.9 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family WD40 PF00400.27 EWM27643.1 - 2.3e-65 214.3 29.2 1.1e-12 47.3 0.3 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EWM27643.1 - 0.0001 20.6 7.4 0.84 7.6 0.0 4.9 3 1 2 5 5 5 3 Nucleoporin Nup120/160 DUF1513 PF07433.6 EWM27643.1 - 0.015 14.2 0.0 7.5 5.3 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) Med31 PF05669.7 EWM27644.1 - 1.2e-33 114.8 4.0 1.6e-33 114.5 2.7 1.1 1 0 0 1 1 1 1 SOH1 YcfA PF07927.7 EWM27644.1 - 0.029 14.2 0.3 2.1 8.3 0.0 3.0 3 0 0 3 3 3 0 YcfA-like protein zf-DHHC PF01529.15 EWM27645.1 - 1.8e-41 141.4 2.9 3.3e-41 140.5 2.0 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase HemY_N PF07219.8 EWM27645.1 - 0.049 13.1 0.3 0.12 11.9 0.2 1.6 1 0 0 1 1 1 0 HemY protein N-terminus HD_4 PF13328.1 EWM27646.1 - 1.5e-46 157.8 0.0 3.1e-46 156.8 0.0 1.5 1 0 0 1 1 1 1 HD domain RelA_SpoT PF04607.12 EWM27646.1 - 2e-22 79.3 0.1 3.7e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins HD PF01966.17 EWM27646.1 - 1.1e-10 41.6 0.1 2.8e-10 40.2 0.0 1.8 1 0 0 1 1 1 1 HD domain TGS PF02824.16 EWM27646.1 - 9.3e-10 38.2 0.0 3.2e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 TGS domain ACT_4 PF13291.1 EWM27646.1 - 0.014 15.7 0.0 0.19 12.0 0.0 2.7 3 0 0 3 3 3 0 ACT domain DUF381 PF04038.7 EWM27646.1 - 0.037 14.0 0.1 0.18 11.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF381) RepB-RCR_reg PF10723.4 EWM27647.1 - 0.28 10.9 0.1 0.28 10.9 0.0 2.7 3 0 0 3 3 3 0 Replication regulatory protein RepB RepB-RCR_reg PF10723.4 EWM27648.1 - 0.028 14.1 0.7 0.16 11.7 0.0 2.3 2 0 0 2 2 2 0 Replication regulatory protein RepB FUSC PF04632.7 EWM27649.1 - 1 7.6 7.8 1.6 7.0 5.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family IncA PF04156.9 EWM27649.1 - 2.1 7.9 50.4 3 7.3 13.7 3.5 2 1 1 3 3 3 0 IncA protein NPV_P10 PF05531.7 EWM27649.1 - 3.5 7.9 16.7 14 6.0 0.2 5.1 3 2 2 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF3584 PF12128.3 EWM27649.1 - 8 3.6 45.5 0.17 9.2 9.3 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) FIST PF08495.5 EWM27650.1 - 2e-08 33.6 0.1 5.5e-07 28.9 0.0 2.8 2 1 0 2 2 2 1 FIST N domain FIST_C PF10442.4 EWM27650.1 - 8.9e-08 32.1 0.1 1.7e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 FIST C domain F-box-like PF12937.2 EWM27650.1 - 0.003 17.2 0.3 0.011 15.4 0.2 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EWM27650.1 - 0.054 13.1 0.4 0.14 11.8 0.3 1.7 1 0 0 1 1 1 0 F-box domain Pur_DNA_glyco PF02245.11 EWM27651.1 - 3.2e-48 163.3 0.0 5e-48 162.6 0.0 1.3 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) LCM PF04072.9 EWM27652.1 - 5e-17 62.0 0.0 2.9e-16 59.5 0.0 2.1 2 1 0 2 2 2 1 Leucine carboxyl methyltransferase 4HBT PF03061.17 EWM27653.1 - 4.5e-08 33.1 0.1 0.00023 21.1 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily PPR PF01535.15 EWM27654.1 - 1.5e-28 96.7 2.3 2.1e-05 24.1 0.0 9.1 9 0 0 9 9 9 7 PPR repeat PPR_2 PF13041.1 EWM27654.1 - 1.2e-27 95.6 0.0 7.7e-05 22.5 0.0 8.2 4 3 5 9 9 9 5 PPR repeat family PPR_3 PF13812.1 EWM27654.1 - 3e-26 89.4 9.7 0.024 14.8 0.0 10.7 10 0 0 10 10 10 6 Pentatricopeptide repeat domain PPR_1 PF12854.2 EWM27654.1 - 1e-09 37.7 0.0 0.15 11.5 0.0 7.0 8 0 0 8 8 8 2 PPR repeat TPR_7 PF13176.1 EWM27654.1 - 0.0016 18.0 0.3 4.3 7.3 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EWM27654.1 - 0.018 14.9 0.9 20 5.1 0.1 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 EWM27654.1 - 0.052 14.1 13.9 28 5.7 0.0 7.7 7 2 2 9 9 9 0 Tetratricopeptide repeat Smr PF01713.16 EWM27654.1 - 0.064 13.4 0.0 0.23 11.7 0.0 2.0 1 1 0 1 1 1 0 Smr domain UPRTase PF14681.1 EWM27654.1 - 0.069 12.3 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Adap_comp_sub PF00928.16 EWM27656.1 - 8.6e-84 280.7 0.0 1.1e-83 280.3 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EWM27656.1 - 5.3e-07 29.4 1.0 1e-06 28.5 0.7 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Longin PF13774.1 EWM27656.1 - 0.05 13.1 0.2 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 Regulated-SNARE-like domain DUF3748 PF12566.3 EWM27657.1 - 0.001 18.9 0.0 0.0012 18.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3748) Myb_DNA-binding PF00249.26 EWM27658.1 - 5.6e-15 55.1 0.3 1.4e-14 53.8 0.2 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EWM27658.1 - 0.00069 19.6 0.1 0.0016 18.4 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain OTU PF02338.14 EWM27659.1 - 1.1e-17 64.7 0.2 1.1e-17 64.7 0.1 2.4 2 1 0 2 2 2 1 OTU-like cysteine protease SEC-C PF02810.10 EWM27659.1 - 8.9e-05 21.9 8.8 0.00021 20.7 6.1 1.7 1 0 0 1 1 1 1 SEC-C motif Peptidase_C65 PF10275.4 EWM27659.1 - 0.0026 17.1 0.0 0.66 9.2 0.0 2.2 2 0 0 2 2 2 2 Peptidase C65 Otubain Myb_DNA-binding PF00249.26 EWM27659.1 - 0.014 15.4 0.3 1.5 8.8 0.0 2.9 3 0 0 3 3 3 0 Myb-like DNA-binding domain Plant_NMP1 PF06694.6 EWM27659.1 - 0.067 12.1 0.0 0.096 11.5 0.0 1.2 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) DUF2997 PF11211.3 EWM27661.1 - 0.0005 19.3 0.0 0.0014 17.9 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2997) Methyltransf_16 PF10294.4 EWM27662.1 - 4.3e-08 32.8 0.0 6e-07 29.0 0.0 2.1 1 1 0 1 1 1 1 Putative methyltransferase DUF1744 PF08490.7 EWM27663.1 - 8.4e-96 320.9 0.0 1.6e-95 320.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 EWM27663.1 - 8.6e-55 185.8 0.0 1.4e-54 185.1 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EWM27663.1 - 1.7e-16 60.0 0.0 8.9e-16 57.7 0.0 2.0 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EWM27663.1 - 1.5e-07 31.1 0.1 4.4e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EWM27663.1 - 5.6e-07 29.5 0.2 3.2e-06 27.0 0.0 2.4 2 0 0 2 2 2 1 RNase_H superfamily Aldedh PF00171.17 EWM27665.1 - 4.2e-111 371.5 1.6 4.9e-111 371.3 1.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TCR PF03638.10 EWM27666.1 - 2.8e-09 36.6 26.5 2.8e-09 36.6 18.3 2.3 2 0 0 2 2 2 1 Tesmin/TSO1-like CXC domain, cysteine-rich domain F-box-like PF12937.2 EWM27666.1 - 0.00041 20.0 0.0 0.00086 18.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like Ribosomal_L18e PF00828.14 EWM27667.1 - 3e-34 118.1 1.1 4.2e-34 117.6 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Acetyltransf_3 PF13302.1 EWM27668.1 - 5.1e-16 59.1 0.0 8.2e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EWM27668.1 - 4.9e-09 36.1 0.0 1.2e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EWM27668.1 - 4.6e-06 26.6 0.0 7e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EWM27668.1 - 4.4e-05 23.4 0.0 6.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GlutR_N PF05201.10 EWM27669.1 - 1.5e-42 144.7 0.0 3.3e-42 143.6 0.0 1.6 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.15 EWM27669.1 - 1.2e-31 109.6 0.0 2.6e-31 108.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GlutR_dimer PF00745.15 EWM27669.1 - 8.1e-22 77.0 2.9 2e-21 75.7 2.0 1.7 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, dimerisation domain OCD_Mu_crystall PF02423.10 EWM27669.1 - 7.5e-06 24.9 0.1 1.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.12 EWM27669.1 - 0.00044 20.6 0.0 0.00044 20.6 0.0 2.4 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EWM27669.1 - 0.0014 18.5 0.2 0.0031 17.3 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 EWM27669.1 - 0.0064 15.9 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GFO_IDH_MocA PF01408.17 EWM27669.1 - 0.01 16.3 0.0 0.034 14.6 0.0 1.9 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Polyketide_cyc PF03364.15 EWM27671.1 - 4.4e-07 29.9 0.2 8e-07 29.0 0.2 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 EWM27671.1 - 0.031 14.4 0.3 0.066 13.3 0.2 1.4 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Metallophos PF00149.23 EWM27672.1 - 0.00033 20.1 2.6 0.0012 18.3 1.8 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DEAD PF00270.24 EWM27673.1 - 2.7e-38 131.0 0.1 4.4e-38 130.4 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EWM27673.1 - 8.1e-20 70.4 1.8 3.9e-10 39.4 0.5 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EWM27673.1 - 0.0039 17.0 0.9 0.0071 16.2 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CobT PF06213.7 EWM27673.1 - 0.024 13.7 15.1 0.02 14.0 3.3 2.5 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Pkinase PF00069.20 EWM27674.1 - 1.7e-39 135.5 0.0 1.9e-26 92.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EWM27674.1 - 2.1e-36 125.3 0.0 2.9e-31 108.5 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EWM27674.1 - 7.7e-08 31.6 0.0 1.2e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Daxx PF03344.10 EWM27674.1 - 8.1 4.7 13.9 11 4.3 9.6 1.1 1 0 0 1 1 1 0 Daxx Family Tir_receptor_C PF07489.6 EWM27675.1 - 0.0089 15.8 0.4 0.0096 15.6 0.3 1.1 1 0 0 1 1 1 1 Translocated intimin receptor (Tir) C-terminus DUF2046 PF09755.4 EWM27675.1 - 0.092 11.6 4.3 0.13 11.1 3.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) DUF2201_N PF13203.1 EWM27675.1 - 0.15 11.2 5.3 0.16 11.1 3.7 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain N-SET PF11764.3 EWM27675.1 - 0.52 10.2 8.0 0.72 9.7 5.5 1.3 1 1 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N ATP11 PF06644.6 EWM27675.1 - 4.1 6.8 7.3 4.6 6.6 5.1 1.0 1 0 0 1 1 1 0 ATP11 protein zf-RanBP PF00641.13 EWM27676.1 - 0.00086 18.3 5.6 0.0014 17.6 3.9 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Zn_clus PF00172.13 EWM27679.1 - 3.5e-06 26.8 14.3 8.4e-06 25.6 9.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF605 PF04652.11 EWM27680.1 - 0.26 10.6 14.9 0.32 10.3 10.3 1.1 1 0 0 1 1 1 0 Vta1 like CS PF04969.11 EWM27682.1 - 1.1e-08 35.5 0.0 1.5e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 CS domain DUF1049 PF06305.6 EWM27682.1 - 0.044 13.2 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DnaJ PF00226.26 EWM27683.1 - 6e-26 89.9 0.6 6e-26 89.9 0.4 1.9 2 0 0 2 2 2 1 DnaJ domain DUF1977 PF09320.6 EWM27683.1 - 2.7e-15 56.5 0.3 6.2e-15 55.3 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) TPR_2 PF07719.12 EWM27683.1 - 0.00028 20.5 0.4 0.0048 16.7 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EWM27683.1 - 0.00052 19.6 0.5 0.0013 18.3 0.0 1.9 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.1 EWM27683.1 - 0.00059 20.4 1.7 0.0019 18.8 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EWM27683.1 - 0.044 13.4 0.1 0.12 12.0 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Ion_trans PF00520.26 EWM27685.1 - 1.9e-26 92.5 25.1 2.4e-14 53.0 9.2 2.6 2 1 0 2 2 2 2 Ion transport protein CDP-OH_P_transf PF01066.16 EWM27687.1 - 1.8e-19 69.9 6.4 1.8e-19 69.9 4.4 2.6 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase SRP9-21 PF05486.7 EWM27688.1 - 2.5e-09 36.7 0.0 3.2e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) AAA PF00004.24 EWM27689.1 - 3.2e-40 137.3 0.0 6.6e-40 136.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EWM27689.1 - 1.1e-06 28.8 0.1 0.00011 22.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EWM27689.1 - 6.5e-06 25.9 0.2 6e-05 22.7 0.1 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EWM27689.1 - 6e-05 23.0 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EWM27689.1 - 7.1e-05 21.8 0.0 0.00011 21.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 EWM27689.1 - 0.00013 22.0 0.1 0.00053 20.0 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EWM27689.1 - 0.0011 18.0 0.0 0.0021 17.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EWM27689.1 - 0.0018 17.6 0.4 0.077 12.3 0.1 2.3 1 1 1 2 2 2 1 AAA domain KaiC PF06745.8 EWM27689.1 - 0.0031 16.6 0.1 0.23 10.5 0.0 2.2 1 1 0 2 2 2 1 KaiC IstB_IS21 PF01695.12 EWM27689.1 - 0.0051 16.2 0.0 0.0091 15.4 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EWM27689.1 - 0.01 15.5 0.2 0.022 14.5 0.2 1.5 1 0 0 1 1 1 0 Part of AAA domain NB-ARC PF00931.17 EWM27689.1 - 0.013 14.3 0.0 0.11 11.3 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.17 EWM27689.1 - 0.015 15.4 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.8 EWM27689.1 - 0.021 13.5 0.0 0.035 12.8 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_3 PF07726.6 EWM27689.1 - 0.022 14.3 0.0 0.058 12.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EWM27689.1 - 0.024 15.4 0.5 0.065 14.0 0.1 2.0 2 1 0 2 2 1 0 AAA domain AAA_18 PF13238.1 EWM27689.1 - 0.027 14.7 0.0 0.067 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EWM27689.1 - 0.029 13.4 0.0 0.048 12.7 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.21 EWM27689.1 - 0.035 13.5 0.0 0.13 11.6 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EWM27689.1 - 0.036 14.1 0.0 0.094 12.7 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.1 EWM27689.1 - 0.04 13.8 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EWM27689.1 - 0.045 13.3 0.1 0.09 12.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EWM27689.1 - 0.046 13.6 0.0 0.098 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EWM27689.1 - 0.056 13.1 0.3 0.13 11.8 0.1 1.7 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.11 EWM27689.1 - 0.056 12.6 0.2 0.17 11.1 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.1 EWM27689.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EWM27689.1 - 0.084 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 EWM27689.1 - 0.12 11.3 0.1 0.18 10.7 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Porin_OmpL1 PF11389.3 EWM27689.1 - 0.19 10.7 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Leptospira porin protein OmpL1 Phos_pyr_kin PF08543.7 EWM27690.1 - 2.5e-76 256.1 0.4 3.9e-76 255.4 0.3 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TMP-TENI PF02581.12 EWM27690.1 - 5.8e-47 159.1 0.0 5.3e-46 156.0 0.0 2.3 3 0 0 3 3 3 1 Thiamine monophosphate synthase/TENI PfkB PF00294.19 EWM27690.1 - 8.4e-09 34.9 0.3 1.4e-08 34.2 0.2 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.12 EWM27690.1 - 3.4e-05 23.2 1.7 0.031 13.5 0.4 2.5 2 1 0 2 2 2 2 Carbohydrate kinase ThiG PF05690.9 EWM27690.1 - 0.016 14.3 0.1 0.033 13.2 0.1 1.5 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Sod_Cu PF00080.15 EWM27691.1 - 2e-26 92.8 0.0 2.7e-20 72.9 0.1 2.3 2 0 0 2 2 2 2 Copper/zinc superoxide dismutase (SODC) Sod_Cu PF00080.15 EWM27692.1 - 2.1e-26 92.7 0.0 3e-20 72.8 0.1 2.3 2 0 0 2 2 2 2 Copper/zinc superoxide dismutase (SODC) Lipase_3 PF01764.20 EWM27693.1 - 4.4e-06 26.3 0.1 2.1e-05 24.1 0.1 2.0 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EWM27693.1 - 0.02 14.6 0.1 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family GlcNAc PF11397.3 EWM27694.1 - 1.9e-66 224.5 0.0 2.4e-66 224.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) 60KD_IMP PF02096.15 EWM27696.1 - 5.5e-24 84.9 0.0 8.6e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein Cwf_Cwc_15 PF04889.7 EWM27697.1 - 5.1e-57 193.3 22.1 5.8e-57 193.2 15.3 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.7 EWM27697.1 - 0.039 13.2 25.0 0.055 12.7 17.3 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 EWM27697.1 - 0.2 9.5 23.8 0.23 9.3 16.5 1.1 1 0 0 1 1 1 0 Nop14-like family Astro_capsid PF03115.9 EWM27697.1 - 0.42 8.8 6.3 0.41 8.8 4.4 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor CDC45 PF02724.9 EWM27697.1 - 0.71 7.8 18.6 0.96 7.3 12.9 1.2 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.7 EWM27697.1 - 0.96 7.7 26.2 1.2 7.4 18.2 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Daxx PF03344.10 EWM27697.1 - 1.9 6.8 21.4 2.5 6.4 14.8 1.2 1 0 0 1 1 1 0 Daxx Family TRAPP PF04051.11 EWM27698.1 - 2.3e-36 124.5 0.1 2.7e-36 124.3 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component C_GCAxxG_C_C PF09719.5 EWM27698.1 - 0.015 15.1 0.1 4.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) Pro_3_hydrox_C PF05373.6 EWM27698.1 - 0.08 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 L-proline 3-hydroxylase, C-terminal RRM_5 PF13893.1 EWM27699.1 - 3e-22 78.2 0.0 3.5e-08 33.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EWM27699.1 - 1.7e-21 75.6 0.0 2e-08 33.7 0.0 4.1 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM27699.1 - 1.5e-20 72.9 0.0 4.4e-06 26.5 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EWM27699.1 - 0.0068 16.1 4.2 3.1 7.6 0.0 4.2 4 1 0 4 4 4 2 Limkain b1 MIP-T3 PF10243.4 EWM27699.1 - 0.18 10.2 49.6 0.37 9.2 34.4 1.5 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 2OG-FeII_Oxy PF03171.15 EWM27700.1 - 0.059 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Chorion_3 PF05387.6 EWM27701.1 - 0.68 9.3 5.8 1.1 8.6 4.0 1.2 1 0 0 1 1 1 0 Chorion family 3 Nuc_sug_transp PF04142.10 EWM27702.1 - 4.9e-80 268.1 13.4 5.1e-45 153.4 0.1 2.9 3 0 0 3 3 3 2 Nucleotide-sugar transporter UAA PF08449.6 EWM27702.1 - 2.4e-07 29.9 0.9 2.4e-07 29.9 0.6 1.5 2 0 0 2 2 2 1 UAA transporter family EamA PF00892.15 EWM27702.1 - 2.2e-06 27.7 2.0 2.2e-06 27.7 1.4 3.1 3 1 0 3 3 3 1 EamA-like transporter family TPT PF03151.11 EWM27702.1 - 3.8e-05 23.3 15.1 0.00045 19.9 5.0 2.4 2 1 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 EWM27702.1 - 0.00043 20.4 0.7 0.00043 20.4 0.5 2.5 2 0 0 2 2 2 1 Multidrug resistance efflux transporter CRAL_TRIO PF00650.15 EWM27704.1 - 3.3e-25 88.4 0.0 5.1e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EWM27704.1 - 5.4e-09 36.1 0.0 8.6e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF592 PF04574.8 EWM27704.1 - 0.057 12.9 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF592) MTP18 PF10558.4 EWM27706.1 - 1e-27 96.8 0.1 1.6e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) CLASP_N PF12348.3 EWM27708.1 - 2.8e-05 23.5 0.1 4.6e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 CLASP N terminal Claudin_3 PF06653.6 EWM27708.1 - 0.024 14.3 1.1 0.042 13.5 0.8 1.3 1 0 0 1 1 1 0 Tight junction protein, Claudin-like DUF92 PF01940.11 EWM27709.1 - 1.6e-73 246.6 11.5 2.3e-73 246.1 8.0 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 CTP_transf_1 PF01148.15 EWM27709.1 - 0.00042 20.0 7.3 0.00088 19.0 5.0 1.5 1 1 0 1 1 1 1 Cytidylyltransferase family Ribosomal_L18ae PF01775.12 EWM27710.1 - 6.3e-56 187.5 0.3 9.6e-56 187.0 0.2 1.3 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Porin_3 PF01459.17 EWM27711.1 - 9.2e-27 94.0 0.1 1.1e-26 93.8 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin Leukocidin PF07968.7 EWM27711.1 - 0.08 12.5 0.1 0.14 11.8 0.0 1.3 1 1 0 1 1 1 0 Leukocidin/Hemolysin toxin family JAB PF01398.16 EWM27712.1 - 1.2e-10 41.1 0.0 2.7e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EWM27712.1 - 4.6e-06 26.1 0.8 7.1e-05 22.3 0.0 2.7 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain PWWP PF00855.12 EWM27712.1 - 5.7e-05 23.2 0.3 0.00012 22.2 0.2 1.6 1 0 0 1 1 1 1 PWWP domain Mpv17_PMP22 PF04117.7 EWM27713.1 - 1e-13 50.6 0.0 2.4e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family Methyltransf_21 PF05050.7 EWM27714.1 - 5.6e-11 42.6 0.0 9.9e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_18 PF12847.2 EWM27714.1 - 5.1e-05 23.8 0.0 9.5e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM27714.1 - 0.0095 15.6 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EWM27714.1 - 0.099 11.3 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) AAA PF00004.24 EWM27715.1 - 4.9e-54 182.0 0.0 6.1e-33 113.8 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EWM27715.1 - 3.7e-12 46.5 9.1 0.00025 21.0 0.1 4.4 2 2 2 4 4 4 3 AAA ATPase domain IstB_IS21 PF01695.12 EWM27715.1 - 1.8e-09 37.2 0.0 0.0003 20.2 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_17 PF13207.1 EWM27715.1 - 2.5e-08 34.7 0.8 0.0026 18.5 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EWM27715.1 - 3.5e-08 33.6 2.5 0.0053 16.9 0.1 4.2 2 2 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EWM27715.1 - 1.5e-07 31.0 1.8 0.024 14.3 0.0 2.8 2 1 0 2 2 2 2 Part of AAA domain NACHT PF05729.7 EWM27715.1 - 1.7e-07 31.0 4.0 9.8e-05 22.0 0.3 3.4 2 2 1 3 3 3 2 NACHT domain AAA_5 PF07728.9 EWM27715.1 - 3.9e-07 29.8 0.0 0.0072 16.0 0.0 2.8 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EWM27715.1 - 6.6e-07 29.3 0.0 0.0021 17.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 EWM27715.1 - 8.1e-07 28.0 0.1 0.004 15.9 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_28 PF13521.1 EWM27715.1 - 1.8e-06 28.0 2.9 0.033 14.1 0.0 3.2 2 1 1 3 3 3 2 AAA domain AAA_18 PF13238.1 EWM27715.1 - 2.5e-06 27.8 0.0 0.092 13.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EWM27715.1 - 6e-06 26.1 0.0 0.16 11.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EWM27715.1 - 1.2e-05 24.8 4.3 0.0011 18.4 0.3 2.8 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EWM27715.1 - 5.7e-05 22.8 0.3 0.0087 15.6 0.0 2.6 3 0 0 3 3 2 1 AAA domain RuvB_N PF05496.7 EWM27715.1 - 7e-05 21.9 0.0 0.32 10.0 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 EWM27715.1 - 0.00018 21.0 0.1 0.0071 15.8 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 EWM27715.1 - 0.00035 20.4 0.0 0.08 12.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EWM27715.1 - 0.00065 19.8 0.1 0.33 11.1 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_29 PF13555.1 EWM27715.1 - 0.00072 19.0 0.6 0.14 11.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain KaiC PF06745.8 EWM27715.1 - 0.0014 17.7 0.0 0.082 12.0 0.0 2.3 2 0 0 2 2 2 1 KaiC Mg_chelatase PF01078.16 EWM27715.1 - 0.0016 17.6 1.4 0.42 9.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 EWM27715.1 - 0.0018 18.6 0.1 0.33 11.2 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_30 PF13604.1 EWM27715.1 - 0.0018 17.8 0.8 0.59 9.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EWM27715.1 - 0.0025 17.4 0.1 0.93 9.1 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 DUF2075 PF09848.4 EWM27715.1 - 0.0047 15.9 0.5 2.4 7.0 0.1 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Hpr_kinase_C PF07475.7 EWM27715.1 - 0.012 14.9 0.6 0.16 11.2 0.0 2.2 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain PhoH PF02562.11 EWM27715.1 - 0.013 14.6 1.6 0.059 12.5 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein T2SE PF00437.15 EWM27715.1 - 0.019 13.8 0.0 0.14 11.0 0.0 2.2 2 1 0 2 2 2 0 Type II/IV secretion system protein RecA PF00154.16 EWM27715.1 - 0.024 13.7 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein CPT PF07931.7 EWM27715.1 - 0.025 14.1 0.1 4.9 6.7 0.0 2.6 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein DUF815 PF05673.8 EWM27715.1 - 0.031 13.2 0.0 0.76 8.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 EWM27715.1 - 0.044 12.8 2.3 1 8.4 0.6 2.3 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.14 EWM27715.1 - 0.056 12.8 0.5 4.9 6.5 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SKI PF01202.17 EWM27715.1 - 0.068 13.0 0.2 14 5.4 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase Viral_helicase1 PF01443.13 EWM27715.1 - 0.073 12.5 0.0 0.51 9.8 0.0 2.3 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_21 PF13304.1 EWM27715.1 - 0.089 12.7 0.0 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EWM27715.1 - 0.11 11.9 0.0 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_3 PF07726.6 EWM27715.1 - 0.15 11.6 0.0 2.7 7.5 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PEPCK_ATP PF01293.15 EWM27715.1 - 0.29 9.6 0.2 0.55 8.6 0.1 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase U-box PF04564.10 EWM27716.1 - 2.2e-17 62.7 0.0 3.9e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 U-box domain FHA PF00498.21 EWM27716.1 - 4.1e-16 58.8 0.0 6.2e-07 29.4 0.0 2.3 2 0 0 2 2 2 2 FHA domain zf-Nse PF11789.3 EWM27716.1 - 1.4e-05 24.4 0.0 2.8e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF1084 PF06454.6 EWM27717.1 - 0.00014 21.0 14.8 0.00027 20.0 10.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) Cellulase PF00150.13 EWM27718.1 - 4.9e-14 52.2 0.6 7.4e-14 51.6 0.4 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MatE PF01554.13 EWM27720.1 - 4.9e-36 123.7 15.0 2.7e-21 75.8 3.2 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt PF01943.12 EWM27720.1 - 0.0022 17.2 8.3 0.3 10.3 1.6 2.4 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein PPR_2 PF13041.1 EWM27721.1 - 4.1e-59 196.3 0.0 3.8e-11 42.7 0.0 12.2 11 2 3 14 14 14 9 PPR repeat family PPR PF01535.15 EWM27721.1 - 1.9e-41 137.1 16.7 0.00011 21.8 0.0 15.3 16 1 0 16 16 16 9 PPR repeat PPR_3 PF13812.1 EWM27721.1 - 1.8e-37 124.4 25.5 2.4e-05 24.2 0.1 14.9 14 1 1 15 15 15 9 Pentatricopeptide repeat domain PPR_1 PF12854.2 EWM27721.1 - 4e-29 99.7 9.3 7e-08 31.8 0.0 9.7 10 1 0 10 10 10 7 PPR repeat Smr PF01713.16 EWM27721.1 - 4e-05 23.7 0.0 0.00013 22.1 0.0 1.9 1 0 0 1 1 1 1 Smr domain Apc3 PF12895.2 EWM27721.1 - 0.0002 21.3 1.8 3 8.0 0.0 6.1 7 1 1 8 8 8 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EWM27721.1 - 0.00039 20.7 0.2 0.21 11.9 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat Glyco_trans_4_3 PF12000.3 EWM27721.1 - 0.072 12.7 0.0 1.3 8.6 0.0 2.6 2 0 0 2 2 2 0 Gkycosyl transferase family 4 group Clathrin PF00637.15 EWM27721.1 - 0.28 10.7 0.0 26 4.4 0.0 3.4 2 1 0 2 2 2 0 Region in Clathrin and VPS DUF1767 PF08585.7 EWM27722.1 - 1.8e-13 50.5 0.0 3.3e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) Pkr1 PF08636.5 EWM27723.1 - 1.7e-08 34.4 1.9 3.2e-08 33.5 1.3 1.4 1 0 0 1 1 1 1 ER protein Pkr1 DUF1772 PF08592.6 EWM27723.1 - 0.0098 15.6 1.0 0.053 13.2 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1772) TspO_MBR PF03073.10 EWM27723.1 - 0.026 14.0 0.4 0.041 13.3 0.3 1.3 1 0 0 1 1 1 0 TspO/MBR family TPR_12 PF13424.1 EWM27724.1 - 1.2e-30 105.2 6.3 3.2e-14 52.6 0.1 2.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 EWM27724.1 - 7.5e-20 70.1 8.9 5.8e-11 41.9 0.4 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EWM27724.1 - 0.00011 21.8 0.1 0.031 13.9 0.0 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EWM27724.1 - 0.00027 20.6 1.1 0.0029 17.3 0.5 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EWM27724.1 - 0.00045 20.1 0.0 0.19 11.9 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 EWM27724.1 - 0.001 19.2 1.9 0.17 12.3 0.0 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EWM27724.1 - 0.0011 19.6 2.2 0.011 16.3 0.2 3.0 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EWM27724.1 - 0.0027 17.2 0.5 0.02 14.4 0.2 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EWM27724.1 - 0.12 12.2 2.8 0.19 11.6 0.2 2.6 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EWM27724.1 - 0.22 11.3 8.0 2.2 8.2 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EWM27724.1 - 0.24 12.1 4.1 21 6.0 0.2 3.4 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EWM27725.1 - 1.2e-43 146.9 21.2 1.7e-13 50.2 0.3 4.5 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 EWM27725.1 - 9.9e-27 92.0 26.6 9e-11 41.3 0.4 7.4 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.1 EWM27725.1 - 3.3e-10 39.4 8.0 0.027 14.1 0.7 4.8 2 1 2 4 4 4 3 TPR repeat TPR_1 PF00515.23 EWM27725.1 - 2.2e-07 30.1 8.8 0.03 13.9 0.2 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EWM27725.1 - 8.2e-07 29.5 8.9 0.018 15.6 0.2 5.3 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EWM27725.1 - 2.6e-06 27.1 4.1 0.29 11.4 0.0 5.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 EWM27725.1 - 6.2e-06 25.7 13.1 0.0045 16.8 0.5 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.9 EWM27725.1 - 0.0022 18.2 2.3 0.26 11.8 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EWM27725.1 - 1.3 8.9 6.7 0.29 11.0 0.2 3.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EWM27725.1 - 2.5 8.1 15.4 3.4 7.6 0.2 5.1 7 0 0 7 7 7 0 Tetratricopeptide repeat VRP3 PF03536.10 EWM27726.1 - 0.16 11.1 0.2 0.19 10.8 0.1 1.1 1 0 0 1 1 1 0 Salmonella virulence-associated 28kDa protein OHCU_decarbox PF09349.5 EWM27727.1 - 5.2e-31 108.0 0.0 9.3e-31 107.2 0.0 1.4 1 1 0 1 1 1 1 OHCU decarboxylase SAP PF02037.22 EWM27728.1 - 3e-07 29.7 0.4 4.7e-07 29.1 0.3 1.3 1 0 0 1 1 1 1 SAP domain HeH PF12949.2 EWM27728.1 - 0.00096 18.6 0.1 0.0015 17.9 0.1 1.4 1 0 0 1 1 1 1 HeH/LEM domain adh_short PF00106.20 EWM27730.1 - 4.8e-10 39.6 0.0 6.8e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EWM27730.1 - 0.0001 22.1 0.0 0.00015 21.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ACPS PF01648.15 EWM27731.1 - 3.4e-13 49.4 0.0 1.3e-12 47.5 0.0 1.9 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily DUF765 PF05570.6 EWM27731.1 - 0.053 13.4 0.2 0.053 13.4 0.1 2.3 2 0 0 2 2 2 0 Circovirus protein of unknown function (DUF765) Ribonuc_red_lgC PF02867.10 EWM27732.1 - 7e-214 711.3 0.0 8.5e-214 711.0 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EWM27732.1 - 6.6e-24 83.5 0.1 2.3e-23 81.7 0.1 2.0 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EWM27732.1 - 1.2e-16 60.8 0.0 5.3e-16 58.8 0.0 2.2 1 0 0 1 1 1 1 ATP cone domain DUF3228 PF11539.3 EWM27735.1 - 7.6e-75 250.3 0.0 9e-75 250.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) Tocopherol_cycl PF14249.1 EWM27735.1 - 0.11 11.2 0.0 0.22 10.2 0.0 1.4 2 0 0 2 2 2 0 Tocopherol cyclase CDC73 PF05179.9 EWM27736.1 - 2.9e-48 164.5 0.0 4.1e-48 164.1 0.0 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family HEAT_2 PF13646.1 EWM27737.1 - 2.1e-16 59.9 6.4 0.0038 17.4 0.0 6.1 3 3 1 5 5 5 5 HEAT repeats HEAT PF02985.17 EWM27737.1 - 3.2e-16 57.8 19.0 0.0015 18.4 0.1 11.1 11 0 0 11 11 11 3 HEAT repeat HEAT_EZ PF13513.1 EWM27737.1 - 6.2e-16 58.3 30.4 0.012 16.0 0.1 12.2 7 3 6 13 13 13 8 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EWM27737.1 - 1.5e-08 34.9 0.0 0.013 15.8 0.0 4.5 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 EWM27737.1 - 5.1e-06 26.3 0.9 3e-05 23.8 0.0 2.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain Arm PF00514.18 EWM27737.1 - 0.00011 21.9 10.6 0.13 12.0 0.1 6.2 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 EWM27737.1 - 0.00043 20.1 0.0 3.8 7.3 0.0 4.6 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 EWM27737.1 - 0.0079 15.5 0.1 2.7 7.3 0.0 3.8 3 2 0 3 3 3 1 CLASP N terminal Adaptin_N PF01602.15 EWM27737.1 - 0.0083 14.4 0.0 2.2 6.5 0.0 3.1 3 0 0 3 3 3 2 Adaptin N terminal region Ipi1_N PF12333.3 EWM27737.1 - 0.059 13.3 1.1 7.1 6.6 0.0 4.3 4 0 0 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation DUF3510 PF12022.3 EWM27738.1 - 2.3e-26 92.3 0.0 1.7e-25 89.5 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3510) COG2 PF06148.6 EWM27738.1 - 9.6e-22 77.2 0.8 9.6e-22 77.2 0.5 1.9 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 TRP PF06011.7 EWM27739.1 - 0.074 11.6 0.2 0.11 11.0 0.1 1.3 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel PC_rep PF01851.17 EWM27740.1 - 4.6e-23 80.0 15.6 2.3e-06 27.5 0.3 7.3 7 0 0 7 7 7 4 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EWM27740.1 - 9.5e-07 29.0 19.0 0.00016 21.9 2.4 5.2 3 1 1 5 5 5 2 HEAT repeats Adaptin_N PF01602.15 EWM27740.1 - 1.9e-05 23.2 0.1 0.73 8.0 0.0 3.9 3 1 1 4 4 4 3 Adaptin N terminal region HEAT_EZ PF13513.1 EWM27740.1 - 8.1e-05 22.9 9.6 0.019 15.4 0.2 4.8 4 0 0 4 4 4 2 HEAT-like repeat HEAT PF02985.17 EWM27740.1 - 0.00014 21.6 0.3 12 6.2 0.0 5.1 5 0 0 5 5 5 1 HEAT repeat TPR_15 PF13429.1 EWM27740.1 - 0.00052 19.1 0.9 0.0017 17.4 0.6 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat Arm PF00514.18 EWM27740.1 - 0.01 15.6 4.2 2.2 8.2 0.0 4.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat PaO PF08417.7 EWM27741.1 - 4.3e-16 58.6 0.1 1.1e-15 57.2 0.1 1.7 1 0 0 1 1 1 1 Pheophorbide a oxygenase Rieske PF00355.21 EWM27741.1 - 3.2e-15 55.4 0.1 1.1e-14 53.7 0.1 1.8 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain Actin PF00022.14 EWM27742.1 - 5e-37 127.2 0.0 1.5e-36 125.7 0.0 1.8 1 0 0 1 1 1 1 Actin DUF365 PF04033.7 EWM27742.1 - 0.29 11.1 3.8 2.4 8.1 0.1 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF365) Pex24p PF06398.6 EWM27742.1 - 0.51 9.0 4.3 4.6 5.9 0.0 2.7 3 0 0 3 3 3 0 Integral peroxisomal membrane peroxin Flagellin_C PF00700.16 EWM27742.1 - 2 8.6 12.8 0.5 10.5 2.3 4.2 4 0 0 4 4 4 0 Bacterial flagellin C-terminal helical region Aldedh PF00171.17 EWM27743.1 - 1.5e-167 557.5 0.0 1.8e-167 557.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Na_H_Exchanger PF00999.16 EWM27744.1 - 1.8e-63 214.3 42.2 2.7e-63 213.7 29.3 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_N PF02254.13 EWM27744.1 - 2.5e-24 85.4 0.0 4.9e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain Glutaredoxin PF00462.19 EWM27744.1 - 0.0038 17.1 0.1 0.22 11.5 0.0 2.7 2 0 0 2 2 2 1 Glutaredoxin DUF1394 PF07159.7 EWM27745.1 - 4.1e-48 164.0 0.0 5.8e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) DUF3411 PF11891.3 EWM27746.1 - 2.4e-36 125.1 0.3 8.4e-35 120.0 0.2 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3411) TPD PF14811.1 EWM27747.1 - 1e-35 122.2 0.0 3.3e-35 120.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function TPD sequence-motif HTH_38 PF13936.1 EWM27747.1 - 0.058 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.1 EWM27747.1 - 0.097 12.3 0.2 0.39 10.4 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain MaoC_dehydratas PF01575.14 EWM27749.1 - 2.9e-25 88.0 0.0 3.5e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 MaoC like domain Tropomyosin_1 PF12718.2 EWM27753.1 - 0.0015 18.3 10.0 0.0023 17.8 6.9 1.2 1 0 0 1 1 1 1 Tropomyosin like Myosin_tail_1 PF01576.14 EWM27753.1 - 0.0026 15.5 9.7 0.0034 15.1 6.8 1.0 1 0 0 1 1 1 1 Myosin tail DUF869 PF05911.6 EWM27753.1 - 0.027 12.7 6.5 0.038 12.2 4.5 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) IncA PF04156.9 EWM27753.1 - 0.064 12.8 0.5 0.1 12.1 0.4 1.2 1 0 0 1 1 1 0 IncA protein Mod_r PF07200.8 EWM27753.1 - 0.1 12.5 6.5 0.16 11.8 4.5 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein APG6 PF04111.7 EWM27753.1 - 0.16 10.9 3.9 0.24 10.3 2.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Casc1 PF12366.3 EWM27753.1 - 3.4 7.0 5.4 6 6.2 3.8 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 Occludin_ELL PF07303.8 EWM27753.1 - 4.6 8.0 10.5 2.3 8.9 5.8 1.5 2 0 0 2 2 2 0 Occludin homology domain NUDIX PF00293.23 EWM27754.1 - 4.3e-23 81.4 0.1 8.4e-23 80.5 0.0 1.5 2 0 0 2 2 2 1 NUDIX domain Epimerase PF01370.16 EWM27755.1 - 3.2e-20 72.5 0.0 4.3e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EWM27755.1 - 4.2e-07 28.9 0.0 6.1e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EWM27755.1 - 1.4e-06 27.4 0.1 8.8e-06 24.8 0.1 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EWM27755.1 - 2.2e-06 26.7 0.0 0.023 13.6 0.1 2.2 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EWM27755.1 - 3.6e-05 22.7 0.0 5.9e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EWM27755.1 - 0.001 19.1 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EWM27755.1 - 0.001 19.0 0.1 0.0023 17.8 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Reprolysin_3 PF13582.1 EWM27755.1 - 0.022 15.3 1.1 0.044 14.3 0.0 2.0 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like KR PF08659.5 EWM27755.1 - 0.032 13.9 0.2 0.094 12.3 0.1 1.7 2 0 0 2 2 2 0 KR domain NmrA PF05368.8 EWM27755.1 - 0.085 12.0 0.2 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family UDPG_MGDP_dh_N PF03721.9 EWM27755.1 - 0.092 12.1 0.2 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HSF_DNA-bind PF00447.12 EWM27756.1 - 1.6e-16 60.3 0.3 2.6e-16 59.6 0.2 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding PX PF00787.19 EWM27757.1 - 2.6e-24 85.2 0.0 4.6e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 EWM27757.1 - 7.8e-15 54.7 0.1 1.3e-14 54.0 0.0 1.4 2 0 0 2 2 2 1 Vps5 C terminal like Sec16 PF12932.2 EWM27758.1 - 0.011 15.6 0.1 0.029 14.3 0.0 1.7 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region DUF2116 PF09889.4 EWM27759.1 - 0.036 13.8 1.9 0.056 13.2 1.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Beach PF02138.13 EWM27760.1 - 1.5e-96 323.0 0.0 1.9e-96 322.6 0.0 1.1 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.27 EWM27760.1 - 1.3e-17 62.9 1.4 1.6e-07 30.9 0.1 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat PH_BEACH PF14844.1 EWM27760.1 - 4.4e-10 39.3 0.2 2.9e-07 30.2 0.0 3.7 3 1 0 3 3 3 1 PH domain associated with Beige/BEACH GRAM PF02893.15 EWM27760.1 - 0.0033 16.9 0.0 1.8 8.1 0.0 2.6 2 0 0 2 2 2 2 GRAM domain NACHT PF05729.7 EWM27760.1 - 0.13 11.8 0.0 0.38 10.4 0.0 1.7 2 0 0 2 2 2 0 NACHT domain DUF382 PF04037.8 EWM27761.1 - 6.8e-55 184.3 0.6 1.4e-54 183.3 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 EWM27761.1 - 4.2e-19 67.6 7.5 1.3e-18 66.0 5.2 1.9 1 0 0 1 1 1 1 PSP Epimerase PF01370.16 EWM27762.1 - 5.9e-15 55.3 0.0 8.7e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family FAST_1 PF06743.10 EWM27763.1 - 1.8e-12 46.7 0.4 0.0046 16.6 0.2 5.7 2 1 5 7 7 7 6 FAST kinase-like protein, subdomain 1 TRAPPC9-Trs120 PF08626.6 EWM27764.1 - 1.7e-12 45.5 0.0 2.2e-12 45.2 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit RAP PF08373.5 EWM27765.1 - 0.031 14.0 0.1 0.33 10.7 0.1 2.2 1 1 0 1 1 1 0 RAP domain Glyco_hydro_3 PF00933.16 EWM27766.1 - 1.2e-65 221.4 0.0 1.6e-65 221.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EWM27766.1 - 1.1e-44 152.6 0.0 1.5e-44 152.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EWM27766.1 - 2.9e-09 36.7 0.0 5.9e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Lipase_3 PF01764.20 EWM27768.1 - 2.5e-13 49.8 0.0 1.3e-10 41.0 0.0 2.3 1 1 1 2 2 2 2 Lipase (class 3) Abhydrolase_3 PF07859.8 EWM27768.1 - 0.051 13.1 0.0 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Pkinase PF00069.20 EWM27769.1 - 7.9e-07 28.4 0.0 1.2e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EWM27769.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 EWM27769.1 - 0.18 10.8 0.0 0.26 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Cofilin_ADF PF00241.15 EWM27770.1 - 8.8e-35 119.3 0.0 1e-34 119.1 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein EF-hand_4 PF12763.2 EWM27771.1 - 5.8e-10 38.8 0.0 1.2e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 EWM27771.1 - 0.0011 18.1 0.0 0.23 10.8 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 EWM27771.1 - 0.024 14.7 0.0 0.055 13.6 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair WEMBL PF05701.6 EWM27771.1 - 0.12 10.8 27.4 0.2 10.0 19.0 1.3 1 0 0 1 1 1 0 Weak chloroplast movement under blue light NYN_YacP PF05991.6 EWM27771.1 - 0.13 11.9 1.1 0.31 10.7 0.4 1.6 1 1 0 1 1 1 0 YacP-like NYN domain CENP-F_leu_zip PF10473.4 EWM27771.1 - 0.73 9.6 20.0 0.024 14.4 2.8 3.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.1 EWM27771.1 - 1 7.7 3.9 1.5 7.2 2.7 1.1 1 0 0 1 1 1 0 AAA domain DUF972 PF06156.8 EWM27771.1 - 1 9.7 9.1 4.2 7.7 1.4 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF972) APG6 PF04111.7 EWM27771.1 - 1.1 8.2 14.2 1.2 8.0 7.4 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF724 PF05266.9 EWM27771.1 - 1.4 8.4 6.7 2.5 7.6 4.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Syntaxin PF00804.20 EWM27771.1 - 2 8.6 6.2 0.58 10.3 0.9 2.2 1 1 1 2 2 2 0 Syntaxin ADIP PF11559.3 EWM27771.1 - 2.5 8.0 16.6 1.1 9.0 0.8 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding HALZ PF02183.13 EWM27771.1 - 2.8 7.7 7.4 0.62 9.8 0.4 3.1 4 0 0 4 4 4 0 Homeobox associated leucine zipper DUF904 PF06005.7 EWM27771.1 - 3.3 8.0 11.6 9.8 6.5 0.9 3.0 2 1 1 3 3 2 0 Protein of unknown function (DUF904) Fez1 PF06818.10 EWM27771.1 - 4.8 7.1 18.9 8.1 6.4 13.1 1.4 1 0 0 1 1 1 0 Fez1 DUF2968 PF11180.3 EWM27771.1 - 6.2 6.1 21.6 2.3 7.5 2.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) IncA PF04156.9 EWM27771.1 - 7 6.2 19.7 5.4 6.5 11.5 2.0 1 1 1 2 2 2 0 IncA protein Orn_Arg_deC_N PF02784.11 EWM27772.1 - 1.5e-27 96.4 0.0 7.3e-19 67.9 0.0 2.7 2 1 0 2 2 2 2 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EWM27772.1 - 1.1e-10 41.2 0.0 1.9e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Hexapep PF00132.19 EWM27773.1 - 1.3e-09 37.1 9.1 0.013 14.9 0.1 4.3 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EWM27773.1 - 0.079 12.5 6.1 0.13 11.8 0.2 3.4 3 1 1 4 4 4 0 Hexapeptide repeat of succinyl-transferase Utp8 PF10395.4 EWM27774.1 - 0.025 12.9 0.7 0.027 12.8 0.5 1.0 1 0 0 1 1 1 0 Utp8 family IF3_C PF00707.17 EWM27775.1 - 6.1e-27 93.1 1.0 1e-26 92.4 0.7 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.11 EWM27775.1 - 8.8e-23 80.0 0.2 1.4e-22 79.3 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain mIF3 PF14877.1 EWM27775.1 - 0.14 11.5 5.3 0.21 10.9 3.6 1.3 1 1 0 1 1 1 0 Mitochondrial translation initiation factor DUF2740 PF10872.3 EWM27775.1 - 2.7 7.7 9.1 2.9 7.6 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2740) Pterin_bind PF00809.17 EWM27776.1 - 2.9e-65 219.5 0.0 4e-65 219.1 0.0 1.2 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 EWM27776.1 - 1e-27 96.3 0.0 2e-27 95.4 0.0 1.5 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) XPG_I PF00867.13 EWM27777.1 - 1.3e-27 95.6 0.0 2.2e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EWM27777.1 - 2.7e-19 69.2 0.0 4.7e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 EWM27777.1 - 1.5e-05 24.6 0.0 2.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing TPR_3 PF07720.7 EWM27777.1 - 0.13 12.1 0.0 0.43 10.4 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat 5_3_exonuc PF01367.15 EWM27777.1 - 0.15 12.3 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold AAA PF00004.24 EWM27778.1 - 3e-94 312.2 0.0 1.8e-45 154.3 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EWM27778.1 - 1.1e-14 54.0 0.0 2.8e-14 52.7 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_17 PF13207.1 EWM27778.1 - 4e-13 50.2 0.0 4.1e-05 24.3 0.0 3.0 2 1 0 2 2 2 2 AAA domain RuvB_N PF05496.7 EWM27778.1 - 5.6e-13 48.4 0.0 2.9e-05 23.2 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EWM27778.1 - 3.3e-11 43.3 0.0 2.3e-05 24.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EWM27778.1 - 4e-11 43.1 0.2 0.00094 19.3 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EWM27778.1 - 4.1e-11 42.9 0.0 0.00018 21.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EWM27778.1 - 7.3e-11 42.3 0.0 0.00064 19.7 0.0 3.2 2 2 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.9 EWM27778.1 - 8.3e-11 41.7 0.0 1.6e-05 24.6 0.0 3.5 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EWM27778.1 - 3.8e-09 35.9 0.3 0.0008 18.5 0.0 3.0 3 0 0 3 3 3 2 Zeta toxin TIP49 PF06068.8 EWM27778.1 - 8.9e-09 34.5 0.0 0.0015 17.3 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 EWM27778.1 - 3.5e-08 33.4 0.0 0.0049 16.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EWM27778.1 - 1.4e-07 30.8 0.2 0.0088 15.2 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI CDC48_2 PF02933.12 EWM27778.1 - 2.9e-07 30.0 0.0 5.9e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_28 PF13521.1 EWM27778.1 - 5.1e-07 29.7 0.0 0.03 14.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EWM27778.1 - 5.2e-07 29.3 0.5 0.02 14.6 0.1 3.0 2 0 0 2 2 2 2 Part of AAA domain IstB_IS21 PF01695.12 EWM27778.1 - 5.5e-07 29.1 0.0 0.034 13.5 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.17 EWM27778.1 - 7e-07 29.3 0.0 0.026 14.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 EWM27778.1 - 8.1e-07 29.4 0.0 0.074 13.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EWM27778.1 - 4.2e-06 26.5 0.1 0.42 10.2 0.0 3.4 3 0 0 3 3 3 2 NACHT domain AAA_25 PF13481.1 EWM27778.1 - 1.1e-05 24.9 2.9 0.18 11.1 0.1 4.0 2 2 1 3 3 3 2 AAA domain Viral_helicase1 PF01443.13 EWM27778.1 - 1.2e-05 24.9 0.0 0.0063 16.0 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Sigma54_activ_2 PF14532.1 EWM27778.1 - 1.4e-05 25.1 0.0 0.18 11.8 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain KaiC PF06745.8 EWM27778.1 - 2.4e-05 23.5 0.0 0.26 10.3 0.0 2.8 2 1 1 3 3 3 2 KaiC AAA_24 PF13479.1 EWM27778.1 - 3.2e-05 23.6 0.2 0.22 11.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 EWM27778.1 - 3.7e-05 24.0 0.0 0.34 11.2 0.0 3.1 3 0 0 3 3 3 2 ABC transporter Arch_ATPase PF01637.13 EWM27778.1 - 6.4e-05 22.7 0.0 1.2 8.7 0.0 3.2 2 1 1 3 3 3 2 Archaeal ATPase Vps4_C PF09336.5 EWM27778.1 - 0.00018 21.3 0.0 0.00088 19.1 0.0 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain NB-ARC PF00931.17 EWM27778.1 - 0.00018 20.4 0.0 0.29 9.9 0.0 2.2 2 0 0 2 2 2 2 NB-ARC domain Cytidylate_kin2 PF13189.1 EWM27778.1 - 0.00022 21.2 1.4 0.1 12.4 0.0 3.0 3 1 0 3 3 2 1 Cytidylate kinase-like family Parvo_NS1 PF01057.12 EWM27778.1 - 0.00027 19.9 0.1 0.45 9.3 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 DUF815 PF05673.8 EWM27778.1 - 0.00032 19.7 0.0 0.53 9.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 EWM27778.1 - 0.00062 19.2 0.0 0.54 9.7 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain SKI PF01202.17 EWM27778.1 - 0.00074 19.4 0.1 1.5 8.6 0.0 2.6 2 0 0 2 2 2 2 Shikimate kinase AAA_3 PF07726.6 EWM27778.1 - 0.0012 18.4 0.0 2 8.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 EWM27778.1 - 0.0014 17.9 0.2 1.9 7.6 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein Bac_DnaA PF00308.13 EWM27778.1 - 0.0022 17.7 0.0 2.3 7.7 0.0 2.5 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_10 PF12846.2 EWM27778.1 - 0.0037 16.7 0.2 5.2 6.4 0.0 3.5 4 0 0 4 4 3 0 AAA-like domain NTPase_1 PF03266.10 EWM27778.1 - 0.0076 15.9 0.0 6.3 6.4 0.0 2.7 2 1 0 2 2 2 0 NTPase AAA_23 PF13476.1 EWM27778.1 - 0.011 16.1 0.0 1.4 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EWM27778.1 - 0.013 15.1 0.0 7.8 6.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF2075 PF09848.4 EWM27778.1 - 0.018 14.0 0.0 2.3 7.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 EWM27778.1 - 0.022 14.5 0.0 2.6 7.8 0.0 2.9 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit T2SE PF00437.15 EWM27778.1 - 0.027 13.3 0.0 3.5 6.4 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.1 EWM27778.1 - 0.071 12.6 0.0 2.9 7.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Rad17 PF03215.10 EWM27778.1 - 0.12 11.0 0.0 1.4 7.5 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein KTI12 PF08433.5 EWM27778.1 - 0.13 11.3 0.1 3.9 6.6 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Zot PF05707.7 EWM27778.1 - 0.15 11.4 0.2 9.8 5.5 0.1 3.2 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) Beach PF02138.13 EWM27782.1 - 2e-88 296.3 0.0 2.6e-88 295.9 0.0 1.1 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 EWM27782.1 - 3.8e-10 39.5 0.0 6.8e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH B12D PF06522.6 EWM27784.1 - 2e-05 24.2 0.0 3.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Histone PF00125.19 EWM27785.1 - 1.2e-27 95.7 2.2 1.9e-27 95.1 0.4 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EWM27785.1 - 0.0027 17.8 0.1 0.0042 17.2 0.1 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S TPR_11 PF13414.1 EWM27786.1 - 5.8e-05 22.6 0.3 0.0001 21.9 0.2 1.3 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 EWM27786.1 - 0.0094 15.5 0.6 0.017 14.7 0.4 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat RRM_1 PF00076.17 EWM27790.1 - 3.1e-08 33.1 0.0 5.7e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM27790.1 - 3.1e-06 27.0 0.0 5.7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM27790.1 - 5.6e-05 22.9 0.0 9.3e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EWM27791.1 - 4.6e-38 127.7 4.5 1.6e-10 40.4 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat PQQ_2 PF13360.1 EWM27791.1 - 0.012 15.0 0.2 0.24 10.8 0.1 2.6 1 1 2 3 3 3 0 PQQ-like domain Nup160 PF11715.3 EWM27791.1 - 0.18 9.9 0.0 0.63 8.1 0.0 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Oxidored-like PF09791.4 EWM27792.1 - 0.014 14.8 2.2 0.027 13.9 1.5 1.4 1 0 0 1 1 1 0 Oxidoreductase-like protein, N-terminal MFS_1 PF07690.11 EWM27793.1 - 6.9e-15 54.6 53.3 3e-07 29.4 17.4 3.5 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 EWM27793.1 - 6.5e-07 28.0 2.1 6.5e-07 28.0 1.5 3.2 2 1 1 3 3 3 1 MFS/sugar transport protein PC-Esterase PF13839.1 EWM27794.1 - 0.00039 20.3 0.0 0.0014 18.4 0.0 1.7 2 0 0 2 2 2 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Peptidase_S9 PF00326.16 EWM27795.1 - 9.8e-44 149.1 0.0 1.5e-43 148.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S51 PF03575.12 EWM27795.1 - 6.6e-27 94.1 0.0 1.2e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S51 Abhydrolase_5 PF12695.2 EWM27795.1 - 4.3e-15 55.7 0.2 2.1e-14 53.5 0.1 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EWM27795.1 - 3.3e-11 43.5 2.6 8.7e-11 42.1 1.1 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EWM27795.1 - 2.1e-08 33.9 0.1 2.4e-05 23.9 0.1 2.3 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 EWM27795.1 - 3.2e-05 23.3 0.1 0.00044 19.6 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.6 EWM27795.1 - 0.00029 20.6 0.0 0.0008 19.1 0.0 1.7 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 EWM27795.1 - 0.0019 17.8 2.2 1.1 8.7 0.0 3.0 3 1 0 3 3 3 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EWM27795.1 - 0.011 15.5 0.0 0.031 14.1 0.0 1.8 1 0 0 1 1 1 0 Putative lysophospholipase PhoPQ_related PF10142.4 EWM27795.1 - 0.014 13.9 0.0 0.02 13.3 0.0 1.1 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Esterase PF00756.15 EWM27795.1 - 0.014 14.8 0.0 0.031 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Abhydrolase_4 PF08386.5 EWM27795.1 - 0.071 13.0 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein LIP PF03583.9 EWM27795.1 - 0.24 10.5 1.1 0.59 9.2 0.6 1.7 2 0 0 2 2 2 0 Secretory lipase PAF-AH_p_II PF03403.8 EWM27795.1 - 0.26 9.5 0.0 15 3.7 0.0 2.1 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Pkinase PF00069.20 EWM27797.1 - 2.9e-42 144.6 0.0 3.6e-42 144.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM27797.1 - 3e-25 88.7 0.0 5.4e-25 87.9 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EWM27797.1 - 2.2e-05 23.6 0.0 3e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EWM27797.1 - 0.013 14.5 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EWM27797.1 - 0.021 14.5 0.1 0.033 13.9 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cu-oxidase_3 PF07732.10 EWM27798.1 - 4.2e-05 23.2 0.3 0.021 14.5 0.2 2.5 1 1 0 1 1 1 1 Multicopper oxidase MgtC PF02308.11 EWM27798.1 - 0.058 13.2 0.0 0.098 12.5 0.0 1.2 1 0 0 1 1 1 0 MgtC family DUF2442 PF10387.4 EWM27798.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2442) UBA PF00627.26 EWM27799.1 - 8.9e-20 69.9 6.2 2.4e-09 36.7 0.0 3.6 4 0 0 4 4 4 2 UBA/TS-N domain ubiquitin PF00240.18 EWM27799.1 - 9.1e-13 47.4 0.0 1.5e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.6 EWM27799.1 - 2.4e-11 42.9 0.0 5.4e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 XPC-binding domain UBA_3 PF09288.5 EWM27799.1 - 0.00021 20.7 0.0 0.35 10.5 0.0 2.5 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain Rad60-SLD_2 PF13881.1 EWM27799.1 - 0.00053 19.8 0.0 0.00094 19.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.11 EWM27799.1 - 0.0015 17.9 0.4 0.049 13.1 0.0 3.3 3 1 0 3 3 3 1 CUE domain Rad60-SLD PF11976.3 EWM27799.1 - 0.0037 16.9 0.1 0.011 15.3 0.0 1.9 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Transthyretin PF00576.16 EWM27800.1 - 5.5e-36 122.8 0.0 7e-36 122.5 0.0 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family ABC2_membrane PF01061.19 EWM27801.1 - 1.6e-37 128.6 7.7 2.7e-37 128.0 5.3 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EWM27801.1 - 5.8e-23 81.7 0.0 1.2e-22 80.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EWM27801.1 - 3.3e-08 33.8 0.1 6.6e-06 26.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 EWM27801.1 - 7.3e-06 25.2 7.2 7.3e-06 25.2 5.0 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_16 PF13191.1 EWM27801.1 - 2.2e-05 24.5 1.0 0.00011 22.2 0.7 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EWM27801.1 - 0.00021 21.4 0.0 0.0012 19.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EWM27801.1 - 0.00043 19.7 0.0 0.013 14.8 0.1 2.3 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EWM27801.1 - 0.00056 19.1 0.1 0.0011 18.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Rad17 PF03215.10 EWM27801.1 - 0.0018 17.0 0.0 0.0026 16.5 0.0 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 EWM27801.1 - 0.0019 17.6 0.0 0.0032 16.9 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_19 PF13245.1 EWM27801.1 - 0.0027 17.4 0.2 0.0096 15.6 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EWM27801.1 - 0.011 16.5 0.1 0.034 14.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.1 EWM27801.1 - 0.011 15.5 0.1 0.038 13.8 0.1 1.9 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.1 EWM27801.1 - 0.019 14.4 0.1 0.047 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 EWM27801.1 - 0.021 13.7 0.1 0.04 12.8 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.7 EWM27801.1 - 0.022 14.4 0.0 0.05 13.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Arch_ATPase PF01637.13 EWM27801.1 - 0.034 13.8 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase SMC_N PF02463.14 EWM27801.1 - 0.066 12.4 0.0 1.4 8.1 0.0 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.1 EWM27801.1 - 0.08 12.9 0.1 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EWM27801.1 - 0.092 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EWM27801.1 - 0.12 12.7 0.1 0.2 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EWM27801.1 - 0.15 11.4 0.2 0.29 10.5 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Fer2 PF00111.22 EWM27804.1 - 1.6e-13 50.2 1.3 2.9e-13 49.3 0.9 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain CYTH PF01928.16 EWM27807.1 - 0.0015 18.2 0.0 0.0025 17.5 0.0 1.2 1 0 0 1 1 1 1 CYTH domain Cu-oxidase_2 PF07731.9 EWM27808.1 - 6.9e-08 32.0 0.0 8e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Multicopper oxidase ATG_C PF09333.6 EWM27812.1 - 4.1e-06 26.8 0.0 8.4e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 ATG C terminal domain Sporozoite_P67 PF05642.6 EWM27812.1 - 0.0021 16.0 3.5 0.0027 15.6 2.4 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen HECT PF00632.20 EWM27813.1 - 3.2e-31 108.6 0.0 3.6e-31 108.5 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HECT PF00632.20 EWM27814.1 - 1.3e-09 37.6 0.0 1.3e-09 37.6 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Zn_peptidase PF04228.8 EWM27816.1 - 0.071 12.3 0.2 0.13 11.4 0.0 1.5 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase DUF4414 PF14377.1 EWM27817.1 - 3.6e-17 62.2 15.3 1.3e-16 60.4 3.7 3.9 2 1 1 3 3 3 2 Domain of unknown function (DUF4414) DUF913 PF06025.7 EWM27821.1 - 7.1e-17 61.2 0.4 9e-17 60.8 0.2 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) UbiA PF01040.13 EWM27823.1 - 1.1e-11 44.4 0.5 4.9e-11 42.3 0.3 1.9 1 1 0 1 1 1 1 UbiA prenyltransferase family UbiA PF01040.13 EWM27825.1 - 3e-08 33.2 0.5 4.4e-08 32.6 0.3 1.3 1 1 0 1 1 1 1 UbiA prenyltransferase family F-box-like PF12937.2 EWM27826.1 - 0.032 13.9 0.0 1.2 8.9 0.0 3.0 2 1 0 2 2 2 0 F-box-like F-box-like PF12937.2 EWM27827.1 - 0.032 13.9 0.0 1.2 8.9 0.0 3.0 2 1 0 2 2 2 0 F-box-like Amidohydro_2 PF04909.9 EWM27828.1 - 8.6e-24 84.5 0.9 1.5e-23 83.7 0.7 1.4 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.9 EWM27829.1 - 8.7e-24 84.5 0.1 1.3e-23 83.9 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Helicase_C PF00271.26 EWM27830.1 - 1.7e-21 75.8 0.1 3.4e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EWM27830.1 - 0.0017 18.3 0.0 0.0091 15.9 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain DUF4407 PF14362.1 EWM27830.1 - 0.6 9.0 9.3 0.94 8.3 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Laminin_EGF PF00053.19 EWM27831.1 - 0.24 11.3 7.9 0.12 12.3 3.3 2.2 2 1 0 2 2 2 0 Laminin EGF-like (Domains III and V) hEGF PF12661.2 EWM27831.1 - 6.2 7.1 8.5 0.34 11.1 1.2 2.7 2 0 0 2 2 2 0 Human growth factor-like EGF ABC_membrane PF00664.18 EWM27832.1 - 1.9e-55 188.2 19.6 1e-31 110.3 3.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EWM27832.1 - 3.9e-43 147.0 0.0 5.6e-27 94.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.1 EWM27832.1 - 4.1e-07 30.1 0.1 0.033 14.1 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EWM27832.1 - 1.2e-06 28.0 2.7 0.0013 18.1 0.0 2.7 3 0 0 3 3 2 2 AAA domain SMC_N PF02463.14 EWM27832.1 - 1.4e-05 24.4 0.0 0.2 10.8 0.0 3.8 2 2 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EWM27832.1 - 2.4e-05 24.4 0.0 1.3 8.8 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_29 PF13555.1 EWM27832.1 - 0.00031 20.1 0.1 0.032 13.7 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EWM27832.1 - 0.00037 20.8 0.0 0.69 10.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EWM27832.1 - 0.0007 20.0 0.0 0.08 13.4 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 EWM27832.1 - 0.001 19.1 0.7 2.7 8.1 0.1 3.2 2 1 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EWM27832.1 - 0.0025 17.5 0.0 0.05 13.3 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase MMR_HSR1 PF01926.18 EWM27832.1 - 0.0086 16.0 0.0 0.16 11.9 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SE PF00437.15 EWM27832.1 - 0.024 13.5 0.0 0.73 8.6 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.1 EWM27832.1 - 0.042 13.4 0.9 1.1 8.7 0.2 2.9 2 1 0 2 2 2 0 AAA domain NACHT PF05729.7 EWM27832.1 - 0.053 13.1 0.2 4.8 6.8 0.0 2.5 2 0 0 2 2 2 0 NACHT domain DUF87 PF01935.12 EWM27832.1 - 0.061 13.1 0.5 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_24 PF13479.1 EWM27832.1 - 0.062 12.8 0.4 0.78 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EWM27832.1 - 0.064 12.4 0.0 5.6 6.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA PF00004.24 EWM27832.1 - 0.18 12.0 0.6 4.9 7.3 0.0 2.9 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EWM27832.1 - 0.25 10.7 0.1 25 4.1 0.1 2.5 2 0 0 2 2 2 0 AAA-like domain Dynamin_N PF00350.18 EWM27832.1 - 0.54 10.0 0.6 6.7 6.5 0.1 2.3 2 0 0 2 2 2 0 Dynamin family ABC_membrane PF00664.18 EWM27833.1 - 1.3e-55 188.8 19.6 8.3e-32 110.6 3.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EWM27833.1 - 5.6e-29 101.1 0.0 2.7e-13 50.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_25 PF13481.1 EWM27833.1 - 2.1e-07 30.5 0.2 0.0011 18.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EWM27833.1 - 6.8e-06 26.1 0.2 0.028 14.4 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EWM27833.1 - 0.00023 20.6 0.1 0.028 13.9 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EWM27833.1 - 0.00028 21.2 0.0 0.59 10.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EWM27833.1 - 0.00055 20.4 0.0 0.072 13.5 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein Arch_ATPase PF01637.13 EWM27833.1 - 0.0019 17.9 0.0 0.042 13.5 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase AAA_21 PF13304.1 EWM27833.1 - 0.003 17.5 0.0 1.9 8.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 EWM27833.1 - 0.0069 16.3 0.0 0.15 12.0 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SE PF00437.15 EWM27833.1 - 0.018 13.9 0.0 0.63 8.8 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.1 EWM27833.1 - 0.036 14.2 0.1 4.7 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 EWM27833.1 - 0.044 12.9 0.0 16 4.6 0.0 2.9 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain NACHT PF05729.7 EWM27833.1 - 0.045 13.3 0.2 4.1 7.0 0.0 2.4 2 0 0 2 2 2 0 NACHT domain DUF258 PF03193.11 EWM27833.1 - 0.048 12.8 0.0 4.8 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 EWM27833.1 - 0.048 13.2 0.4 0.67 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EWM27833.1 - 0.049 13.4 0.5 0.96 9.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_10 PF12846.2 EWM27833.1 - 0.32 10.3 0.4 22 4.3 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain Dynamin_N PF00350.18 EWM27833.1 - 0.43 10.3 0.6 5.8 6.7 0.1 2.3 2 0 0 2 2 2 0 Dynamin family ECH PF00378.15 EWM27835.1 - 3.2e-60 203.3 0.0 3.8e-60 203.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family SDH_sah PF01972.11 EWM27835.1 - 0.01 14.6 0.0 0.023 13.4 0.0 1.6 2 0 0 2 2 2 0 Serine dehydrogenase proteinase Carboxyl_trans PF01039.17 EWM27835.1 - 0.094 11.0 0.1 0.13 10.5 0.0 1.1 1 0 0 1 1 1 0 Carboxyl transferase domain IFT46_B_C PF12317.3 EWM27836.1 - 1.8e-28 99.3 0.2 2.7e-28 98.8 0.1 1.2 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal NAD_binding_1 PF00175.16 EWM27838.1 - 6.1e-10 39.6 1.4 5e-08 33.4 1.0 2.9 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EWM27838.1 - 0.00013 21.9 0.0 0.12 12.3 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain XPG_N PF00752.12 EWM27839.1 - 1.8e-30 105.1 0.0 3.2e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EWM27839.1 - 5.6e-30 103.2 0.1 1.1e-29 102.2 0.0 1.5 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 EWM27839.1 - 2.4e-07 30.9 0.1 9.5e-07 28.9 0.0 2.0 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold 5_3_exonuc_N PF02739.11 EWM27839.1 - 0.04 13.2 0.0 0.096 12.0 0.0 1.6 2 0 0 2 2 2 0 5'-3' exonuclease, N-terminal resolvase-like domain BT1 PF03092.11 EWM27840.1 - 3.3e-48 164.4 16.5 5e-48 163.8 11.4 1.2 1 0 0 1 1 1 1 BT1 family BT1 PF03092.11 EWM27841.1 - 2e-17 63.0 7.0 5.6e-17 61.5 4.8 1.6 1 1 0 1 1 1 1 BT1 family Ank_2 PF12796.2 EWM27842.1 - 1.1e-18 67.3 0.0 1.7e-10 41.0 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EWM27842.1 - 6.6e-15 54.0 5.4 3.7e-06 26.4 0.1 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 EWM27842.1 - 1.4e-14 53.7 0.1 0.034 14.3 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EWM27842.1 - 1.6e-12 47.5 0.7 2.6e-05 24.5 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM27842.1 - 1.8e-11 43.1 3.9 0.00083 19.3 0.1 5.7 5 0 0 5 5 5 2 Ankyrin repeat Glycos_transf_2 PF00535.21 EWM27846.1 - 9.7e-13 48.1 0.0 1.4e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EWM27846.1 - 1.7e-06 27.9 0.0 2.2e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Fringe PF02434.11 EWM27846.1 - 0.0046 16.2 0.0 0.0061 15.7 0.0 1.2 1 0 0 1 1 1 1 Fringe-like zf-C3HC4_3 PF13920.1 EWM27847.1 - 1e-05 25.0 14.0 1.4e-05 24.6 9.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EWM27847.1 - 0.064 13.2 13.8 0.18 11.8 9.6 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PolC_DP2 PF03833.8 EWM27847.1 - 3.3 5.2 7.8 3.5 5.1 5.4 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF1759 PF03564.10 EWM27849.1 - 0.00032 20.5 0.2 0.00042 20.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) UBN2_2 PF14227.1 EWM27849.1 - 0.014 14.8 0.2 0.022 14.2 0.1 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type YchF-GTPase_C PF06071.8 EWM27850.1 - 2e-40 136.4 0.0 3.5e-40 135.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EWM27850.1 - 2.5e-19 69.3 0.0 5.4e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EWM27850.1 - 1.1e-07 31.2 0.1 3.2e-07 29.7 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_17 PF13207.1 EWM27850.1 - 0.081 13.7 0.0 0.18 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EWM27850.1 - 0.12 12.7 0.1 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 ABC transporter zf-CCHC PF00098.18 EWM27851.1 - 0.0027 17.5 16.3 0.0074 16.1 3.2 2.7 2 0 0 2 2 2 2 Zinc knuckle eIF3g PF12353.3 EWM27851.1 - 0.044 13.7 0.4 0.044 13.7 0.3 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_4 PF14392.1 EWM27851.1 - 0.045 13.4 11.5 0.26 11.0 1.3 3.1 3 1 0 3 3 3 0 Zinc knuckle zf-CCHC_3 PF13917.1 EWM27851.1 - 0.15 11.7 11.4 0.057 13.1 1.8 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.1 EWM27851.1 - 0.3 10.6 15.5 0.45 10.0 1.4 3.0 2 1 1 3 3 3 0 GAG-polyprotein viral zinc-finger DUF179 PF02622.10 EWM27853.1 - 2e-10 40.5 0.0 3.1e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 Methyltransf_18 PF12847.2 EWM27854.1 - 1e-15 58.2 0.0 2.9e-07 31.0 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 EWM27854.1 - 7.3e-15 55.2 0.0 3.1e-10 40.4 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 EWM27854.1 - 2.8e-13 49.7 0.0 5.4e-08 32.5 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 EWM27854.1 - 3.7e-11 43.2 0.0 1.8e-07 31.4 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 EWM27854.1 - 5.5e-10 39.3 0.0 0.00015 21.8 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_PK PF05891.7 EWM27854.1 - 2.6e-07 30.1 0.0 5.1e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 EWM27854.1 - 2.7e-06 27.1 0.0 0.027 14.2 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.9 EWM27854.1 - 0.0003 20.2 0.0 0.19 11.1 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase small domain NodS PF05401.6 EWM27854.1 - 0.00035 20.0 0.0 0.00057 19.3 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.15 EWM27854.1 - 0.0005 19.1 0.0 0.00098 18.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase 4HBT PF03061.17 EWM27855.1 - 1.6e-12 47.3 0.0 3.4e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.1 EWM27855.1 - 0.0022 18.4 0.0 0.0051 17.2 0.0 1.6 1 1 0 1 1 1 1 Thioesterase-like superfamily CAP59_mtransfer PF11735.3 EWM27856.1 - 2.1e-49 167.9 0.0 2.5e-29 102.2 0.0 2.2 2 0 0 2 2 2 2 Cryptococcal mannosyltransferase 1 DUF221 PF02714.10 EWM27857.1 - 7.2e-68 228.8 15.8 7.2e-68 228.8 11.0 1.8 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EWM27857.1 - 3.4e-32 111.1 2.8 3.8e-28 98.0 0.0 3.4 3 0 0 3 3 3 2 Late exocytosis, associated with Golgi transport MFS_1 PF07690.11 EWM27858.1 - 4.7e-39 134.1 31.0 1.2e-24 86.7 12.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EWM27858.1 - 1.1e-10 40.5 13.0 1.4e-07 30.2 0.1 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 EWM27858.1 - 4e-10 38.8 17.5 1.6e-09 36.9 10.8 2.1 1 1 1 2 2 2 1 Sugar (and other) transporter DUF2162 PF09930.4 EWM27858.1 - 0.0021 17.2 0.9 0.0021 17.2 0.6 2.5 2 1 0 2 2 2 1 Predicted transporter (DUF2162) DUF1228 PF06779.9 EWM27858.1 - 0.0063 16.5 1.5 0.028 14.4 1.1 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1228) MFS_1_like PF12832.2 EWM27858.1 - 0.011 15.4 0.2 0.074 12.8 0.0 2.4 2 0 0 2 2 2 0 MFS_1 like family PA PF02225.17 EWM27859.1 - 1.7e-07 30.8 0.0 2.6e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 PA domain SRP19 PF01922.12 EWM27860.1 - 1.4e-24 86.4 0.0 2.7e-24 85.5 0.0 1.5 1 0 0 1 1 1 1 SRP19 protein K_channel_TID PF07941.6 EWM27860.1 - 2.3 8.5 17.1 1.2 9.4 6.5 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain TPR_2 PF07719.12 EWM27861.1 - 2.9e-11 42.3 17.2 5.7e-05 22.7 0.2 10.0 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_8 PF13181.1 EWM27861.1 - 1.4e-10 40.2 3.6 0.039 13.7 0.1 8.8 10 0 0 10 10 8 1 Tetratricopeptide repeat Suf PF05843.9 EWM27861.1 - 7.5e-10 38.9 11.5 0.00095 18.9 2.1 4.9 4 2 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EWM27861.1 - 8.6e-10 38.3 21.1 0.0014 19.0 0.0 12.1 11 2 3 14 14 12 1 Tetratricopeptide repeat TPR_11 PF13414.1 EWM27861.1 - 4.1e-09 35.9 9.8 0.044 13.4 0.0 7.8 7 1 2 9 9 9 3 TPR repeat Mad3_BUB1_I PF08311.7 EWM27861.1 - 5.5e-08 32.6 16.2 0.012 15.3 0.1 7.5 7 1 1 8 8 8 2 Mad3/BUB1 homology region 1 TPR_15 PF13429.1 EWM27861.1 - 6.8e-08 31.8 21.9 0.0013 17.8 0.1 6.3 7 2 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 EWM27861.1 - 2.6e-06 26.7 11.4 0.0077 15.8 0.1 7.7 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_19 PF14559.1 EWM27861.1 - 8e-06 26.1 13.2 0.16 12.3 0.0 7.8 7 1 0 8 8 7 1 Tetratricopeptide repeat HAT PF02184.11 EWM27861.1 - 3.2e-05 23.5 3.9 4.5 7.0 0.1 5.8 4 0 0 4 4 4 1 HAT (Half-A-TPR) repeat TPR_7 PF13176.1 EWM27861.1 - 5.2e-05 22.7 15.5 0.0023 17.5 0.1 7.7 10 0 0 10 10 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 EWM27861.1 - 0.0001 22.1 21.2 0.0099 15.7 0.0 7.7 6 2 2 9 9 9 2 Tetratricopeptide repeat RPN7 PF10602.4 EWM27861.1 - 0.0011 18.3 0.9 1.9 7.8 0.1 3.0 2 1 0 2 2 2 2 26S proteasome subunit RPN7 TPR_16 PF13432.1 EWM27861.1 - 0.007 17.0 30.1 0.059 14.0 0.0 7.5 8 0 0 8 8 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EWM27861.1 - 0.0084 16.2 5.8 8.2 6.9 0.0 6.0 7 0 0 7 7 6 1 Tetratricopeptide repeat NRDE-2 PF08424.5 EWM27861.1 - 0.024 13.5 13.1 0.037 12.9 2.0 5.2 3 2 1 4 4 4 0 NRDE-2, necessary for RNA interference TPR_10 PF13374.1 EWM27861.1 - 0.041 13.8 9.8 0.046 13.6 0.1 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 EWM27861.1 - 1.3 9.6 0.0 1.3 9.6 0.0 4.3 5 0 0 5 5 2 0 Tetratricopeptide repeat Nrap PF03813.9 EWM27863.1 - 2.9e-128 428.9 0.0 8.5e-117 391.0 0.0 2.2 2 0 0 2 2 2 2 Nrap protein CRCB PF02537.10 EWM27866.1 - 1.5e-28 99.0 10.3 6.4e-18 64.7 0.4 2.2 2 0 0 2 2 2 2 CrcB-like protein DUF4035 PF13227.1 EWM27866.1 - 0.11 11.8 0.0 0.28 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4035) Spore_permease PF03845.8 EWM27866.1 - 0.5 8.9 4.0 0.36 9.4 1.1 1.8 2 0 0 2 2 2 0 Spore germination protein Sua5_yciO_yrdC PF01300.13 EWM27868.1 - 4.3e-45 153.1 0.7 1.7e-43 147.9 0.0 2.9 2 1 0 2 2 2 1 Telomere recombination SUA5 PF03481.8 EWM27868.1 - 5.9e-10 39.3 0.0 1.2e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Hydrolase_3 PF08282.7 EWM27870.1 - 9.1e-50 169.5 0.0 1.2e-48 165.8 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EWM27870.1 - 2.6e-11 43.3 0.0 2.6e-09 36.7 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 EWM27870.1 - 1.7e-06 28.5 0.0 0.028 14.8 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.11 EWM27870.1 - 0.0068 15.3 0.0 0.013 14.4 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase PRCC PF10253.4 EWM27870.1 - 0.085 13.5 0.2 1.8 9.2 0.6 2.2 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting HAD PF12710.2 EWM27870.1 - 0.098 12.8 0.0 0.53 10.4 0.0 2.1 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EWM27870.1 - 0.16 11.8 0.0 0.69 9.8 0.0 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EWM27870.1 - 0.18 11.9 0.0 2.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF2870 PF11069.3 EWM27871.1 - 7.3e-28 96.4 0.0 1.5e-27 95.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) ABC_membrane PF00664.18 EWM27872.1 - 1.2e-67 228.2 22.7 2.6e-34 118.8 5.3 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 EWM27872.1 - 4.2e-52 176.0 0.0 2.8e-29 102.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EWM27872.1 - 1.2e-08 34.4 3.1 0.027 13.6 0.0 4.1 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EWM27872.1 - 1.8e-07 30.7 0.2 0.0018 17.6 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 EWM27872.1 - 7.4e-07 29.4 0.4 0.011 15.7 0.0 4.2 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EWM27872.1 - 2.1e-06 27.1 1.1 0.039 13.4 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EWM27872.1 - 8.2e-05 22.1 0.1 0.54 9.6 0.1 2.8 3 0 0 3 3 3 2 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 EWM27872.1 - 9.5e-05 22.3 0.0 0.021 14.7 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EWM27872.1 - 0.00013 22.4 0.1 0.27 11.7 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_23 PF13476.1 EWM27872.1 - 0.00022 21.6 2.7 0.63 10.3 0.1 3.0 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 EWM27872.1 - 0.00024 20.3 0.3 0.48 9.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EWM27872.1 - 0.0016 18.4 4.8 0.63 10.0 0.8 2.7 2 1 0 2 2 2 2 AAA ATPase domain NTPase_1 PF03266.10 EWM27872.1 - 0.0032 17.1 0.1 0.022 14.4 0.0 2.3 2 1 0 2 2 2 1 NTPase DUF87 PF01935.12 EWM27872.1 - 0.0063 16.3 2.3 0.38 10.5 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 Dynamin_N PF00350.18 EWM27872.1 - 0.0073 16.1 1.0 3.3 7.5 0.1 3.1 3 0 0 3 3 3 1 Dynamin family AAA_22 PF13401.1 EWM27872.1 - 0.013 15.6 1.6 2.7 8.1 0.2 3.3 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EWM27872.1 - 0.016 14.2 1.5 2.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin T2SE PF00437.15 EWM27872.1 - 0.017 14.0 0.2 5.3 5.8 0.1 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein SbcCD_C PF13558.1 EWM27872.1 - 0.019 14.8 0.0 5.3 7.0 0.0 3.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.20 EWM27872.1 - 0.071 12.5 0.0 11 5.3 0.0 2.5 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_10 PF12846.2 EWM27872.1 - 0.1 12.0 0.6 15 4.8 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain TrwB_AAD_bind PF10412.4 EWM27872.1 - 0.28 9.7 1.7 7.2 5.1 0.0 2.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.14 EWM27872.1 - 2.1 7.7 6.6 8.6 5.7 0.1 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain PMSR PF01625.16 EWM27874.1 - 2.4e-55 186.6 0.1 3e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Abhydrolase_6 PF12697.2 EWM27875.1 - 2.9e-08 33.8 2.4 3.4e-07 30.3 0.4 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EWM27875.1 - 1.7e-06 27.1 0.0 0.00023 20.1 0.0 2.9 3 0 0 3 3 3 1 Chlorophyllase enzyme Abhydrolase_5 PF12695.2 EWM27875.1 - 4.3e-05 23.2 0.0 0.00011 22.0 0.0 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EWM27875.1 - 0.00037 20.8 0.0 0.00059 20.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Ser_hydrolase PF06821.8 EWM27875.1 - 0.00054 19.6 0.0 0.00094 18.8 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_1 PF00561.15 EWM27875.1 - 0.0019 17.8 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold ETF PF01012.16 EWM27875.1 - 0.032 13.9 0.1 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 Electron transfer flavoprotein domain Abhydrolase_3 PF07859.8 EWM27875.1 - 0.033 13.7 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3530 PF12048.3 EWM27875.1 - 0.043 12.8 0.0 0.06 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DUF2974 PF11187.3 EWM27875.1 - 0.049 12.9 0.0 0.077 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF2305 PF10230.4 EWM27875.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF900 PF05990.7 EWM27875.1 - 0.19 11.0 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) K_channel_TID PF07941.6 EWM27875.1 - 0.9 9.8 5.7 2.6 8.3 0.3 2.6 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Ank_4 PF13637.1 EWM27876.1 - 2.9e-16 59.5 0.2 2.7e-08 34.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EWM27876.1 - 1.6e-15 57.2 0.0 1.1e-14 54.5 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EWM27876.1 - 4.5e-13 48.2 0.0 8e-06 25.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EWM27876.1 - 1.4e-12 47.4 0.1 6.1e-10 39.0 0.0 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM27876.1 - 5.6e-09 35.3 0.0 0.003 17.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat DUF605 PF04652.11 EWM27876.1 - 0.88 8.8 9.3 1.2 8.4 6.5 1.1 1 0 0 1 1 1 0 Vta1 like zf-RING_2 PF13639.1 EWM27877.1 - 8.4e-13 47.9 5.3 2.7e-12 46.3 3.6 2.0 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EWM27877.1 - 8.8e-09 35.3 2.2 8.8e-09 35.3 1.5 2.6 3 0 0 3 3 3 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EWM27877.1 - 3.7e-06 26.8 4.3 9.2e-06 25.5 3.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EWM27877.1 - 4.2e-05 23.1 2.0 9.3e-05 22.0 1.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EWM27877.1 - 0.00015 21.3 4.7 0.00015 21.3 3.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EWM27877.1 - 0.00061 19.4 3.6 0.0015 18.1 2.5 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EWM27877.1 - 0.0018 18.0 0.9 0.0086 15.8 0.6 2.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EWM27877.1 - 0.011 15.8 5.5 0.024 14.6 3.8 1.7 1 0 0 1 1 1 0 RING-variant domain Atx10homo_assoc PF09759.4 EWM27877.1 - 0.042 13.5 0.2 0.34 10.6 0.0 2.6 4 0 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain zf-RING_4 PF14570.1 EWM27877.1 - 0.52 9.9 5.2 0.23 11.0 1.7 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF1620 PF07774.8 EWM27878.1 - 3.8e-51 173.4 0.0 5.4e-51 172.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 EWM27878.1 - 4.6e-07 29.5 0.5 0.11 11.8 0.0 3.5 2 1 1 3 3 3 3 PQQ-like domain Peptidase_M20 PF01546.23 EWM27879.1 - 1.5e-26 93.0 0.0 3.9e-26 91.7 0.0 1.8 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 EWM27879.1 - 2.3e-21 74.8 4.5 2.4e-07 30.3 0.1 4.5 5 0 0 5 5 5 3 WD domain, G-beta repeat M20_dimer PF07687.9 EWM27879.1 - 1.4e-11 44.1 0.0 3.5e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 Peptidase dimerisation domain CytoC_RC PF02276.13 EWM27879.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Photosynthetic reaction centre cytochrome C subunit SLIDE PF09111.5 EWM27880.1 - 2.9e-33 114.0 0.8 6.7e-33 112.9 0.6 1.7 1 0 0 1 1 1 1 SLIDE HAND PF09110.6 EWM27880.1 - 1.2e-08 35.3 0.0 1.2e-08 35.3 0.0 2.9 3 0 0 3 3 3 1 HAND Myb_DNA-bind_6 PF13921.1 EWM27880.1 - 4.2e-05 23.5 2.3 7.2e-05 22.8 0.3 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EWM27880.1 - 0.073 13.1 0.6 0.5 10.4 0.2 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain Esterase_phd PF10503.4 EWM27881.1 - 9.5e-13 47.9 0.1 1.4e-12 47.3 0.1 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 EWM27881.1 - 3.9e-09 36.4 0.0 8.3e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EWM27881.1 - 7.2e-07 29.3 1.1 4.2e-06 26.8 0.3 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EWM27881.1 - 4.1e-06 26.1 0.0 1.1e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EWM27881.1 - 0.0004 20.0 0.0 0.00065 19.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EWM27881.1 - 0.0093 15.5 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EWM27881.1 - 0.023 14.1 0.0 0.038 13.4 0.0 1.4 1 1 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.11 EWM27881.1 - 0.038 13.4 0.1 0.16 11.4 0.1 1.8 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase DUF1049 PF06305.6 EWM27881.1 - 0.092 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) AXE1 PF05448.7 EWM27881.1 - 0.21 10.0 0.0 0.45 8.9 0.0 1.5 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Sugar_tr PF00083.19 EWM27882.1 - 1.4e-97 327.1 26.9 1.7e-97 326.8 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EWM27882.1 - 8.7e-30 103.6 53.4 3.2e-28 98.4 22.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily L51_S25_CI-B8 PF05047.11 EWM27883.1 - 1.7e-07 30.8 0.0 2.7e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain GATase_4 PF13230.1 EWM27884.1 - 4.1e-12 45.3 0.0 9.3e-11 40.9 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 EWM27884.1 - 3.2e-11 43.2 0.0 6.6e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain WD40 PF00400.27 EWM27884.1 - 1.2e-07 31.3 0.2 0.00018 21.2 0.0 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat GATase_2 PF00310.16 EWM27884.1 - 2.5e-06 26.4 0.0 2.2e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferases class-II PQQ_3 PF13570.1 EWM27884.1 - 0.006 16.8 0.8 2.9 8.3 0.0 3.7 3 0 0 3 3 3 1 PQQ-like domain Nup160 PF11715.3 EWM27884.1 - 0.12 10.5 0.1 5.1 5.1 0.0 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 TPR_19 PF14559.1 EWM27885.1 - 8e-11 42.1 30.4 0.046 14.0 0.0 8.0 4 1 2 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 EWM27885.1 - 5e-08 32.9 0.3 0.00079 19.5 0.1 3.7 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EWM27885.1 - 4.7e-07 29.6 23.7 0.0016 18.3 0.1 7.2 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.1 EWM27885.1 - 9.9e-07 28.3 15.4 0.0023 17.5 0.0 6.3 6 1 1 7 7 7 1 TPR repeat TPR_2 PF07719.12 EWM27885.1 - 1.2e-05 24.8 22.9 0.0034 17.1 0.0 8.6 9 0 0 9 9 9 1 Tetratricopeptide repeat PPR PF01535.15 EWM27885.1 - 3e-05 23.6 0.3 0.45 10.5 0.0 5.2 5 0 0 5 5 5 1 PPR repeat SRP72 PF08492.7 EWM27885.1 - 7.5e-05 23.0 5.4 0.00018 21.7 3.8 1.7 1 0 0 1 1 1 1 SRP72 RNA-binding domain TPR_1 PF00515.23 EWM27885.1 - 8.3e-05 22.0 3.6 0.032 13.8 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 EWM27885.1 - 0.00015 22.3 53.3 0.0014 19.2 0.5 8.2 5 3 4 9 9 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 EWM27885.1 - 0.00072 19.1 2.1 0.35 10.7 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 EWM27885.1 - 0.007 16.1 25.6 0.074 12.9 1.1 6.6 6 1 2 8 8 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 EWM27885.1 - 0.073 13.7 49.5 0.37 11.5 0.0 10.9 8 3 2 11 11 11 0 Tetratricopeptide repeat PPR_1 PF12854.2 EWM27885.1 - 0.078 12.4 0.7 2.7 7.5 0.0 3.2 3 0 0 3 3 3 0 PPR repeat TPR_10 PF13374.1 EWM27885.1 - 0.11 12.4 18.2 0.6 10.1 0.3 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat PPR_2 PF13041.1 EWM27885.1 - 0.18 11.8 0.1 1.5 8.8 0.0 2.5 2 0 0 2 2 2 0 PPR repeat family WHG PF13305.1 EWM27885.1 - 0.36 11.4 4.5 18 5.9 0.2 4.2 4 0 0 4 4 4 0 WHG domain TPR_4 PF07721.9 EWM27885.1 - 0.4 11.2 46.2 3.2 8.4 0.4 9.2 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 EWM27885.1 - 1.4 9.5 0.0 1.4 9.5 0.0 7.7 9 0 0 9 9 7 0 Tetratricopeptide repeat SNF2_N PF00176.18 EWM27886.1 - 2.9e-51 174.0 0.0 3.7e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EWM27886.1 - 0.00025 20.9 0.0 0.00045 20.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 EWM27886.1 - 0.0047 15.7 0.0 0.073 11.8 0.0 2.5 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_14 PF13173.1 EWM27886.1 - 0.0056 16.5 0.0 0.027 14.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain DEAD_2 PF06733.10 EWM27886.1 - 0.0067 15.8 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 DEAD_2 AAA_10 PF12846.2 EWM27886.1 - 0.011 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain DEAD PF00270.24 EWM27886.1 - 0.018 14.5 0.0 0.036 13.5 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase Helicase_C PF00271.26 EWM27886.1 - 0.029 14.2 0.0 0.06 13.2 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain DUF3306 PF11748.3 EWM27889.1 - 2.2 8.9 9.6 4.4 7.9 1.8 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3306) Peptidase_C1 PF00112.18 EWM27891.1 - 1.2e-51 175.7 0.1 2.1e-51 174.8 0.1 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EWM27891.1 - 9.6e-11 41.8 0.2 1.8e-10 40.9 0.1 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 EWM27891.1 - 0.0014 17.1 0.3 0.0022 16.5 0.2 1.2 1 0 0 1 1 1 1 Peptidase C1-like family DUF809 PF05663.6 EWM27892.1 - 1 9.2 3.9 1.5 8.7 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF809) Apt1 PF10351.4 EWM27893.1 - 0.087 11.6 2.7 0.098 11.4 1.9 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Sporozoite_P67 PF05642.6 EWM27893.1 - 0.15 9.8 9.3 0.19 9.5 6.5 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen EamA PF00892.15 EWM27894.1 - 1.9e-18 66.6 13.9 1.1e-08 35.1 0.6 2.9 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EWM27894.1 - 1e-06 28.8 13.1 0.00011 22.3 0.4 3.2 3 1 0 3 3 3 2 Multidrug resistance efflux transporter PK PF00224.16 EWM27895.1 - 9.1e-144 478.3 1.3 2.3e-143 477.0 0.8 1.6 2 0 0 2 2 2 1 Pyruvate kinase, barrel domain Suc_Fer-like PF06999.7 EWM27895.1 - 7.8e-28 98.0 0.0 2.5e-27 96.3 0.0 1.8 1 1 0 1 1 1 1 Sucrase/ferredoxin-like PK_C PF02887.11 EWM27895.1 - 5.7e-26 90.3 0.5 1.4e-25 89.0 0.4 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EWM27895.1 - 0.00072 18.5 0.0 0.0013 17.7 0.0 1.4 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family REF PF05755.7 EWM27895.1 - 0.034 13.8 0.1 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) FleQ PF06490.6 EWM27895.1 - 0.18 11.9 0.0 1.1 9.4 0.0 2.2 1 1 1 2 2 2 0 Flagellar regulatory protein FleQ DUF872 PF05915.7 EWM27896.1 - 2.8e-15 56.1 0.0 3.1e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) DUF3040 PF11239.3 EWM27896.1 - 0.16 12.0 0.4 1.1 9.3 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) PepSY_TM PF03929.11 EWM27896.1 - 1.1 9.8 3.8 24 5.6 1.8 2.7 2 1 0 2 2 2 0 PepSY-associated TM helix AAA_23 PF13476.1 EWM27899.1 - 0.095 13.0 4.6 0.1 12.8 3.2 1.1 1 0 0 1 1 1 0 AAA domain Ilar_coat PF01787.11 EWM27899.1 - 0.13 11.8 2.2 0.095 12.2 0.5 1.4 1 1 0 1 1 1 0 Ilarvirus coat protein Spore_coat_CotO PF14153.1 EWM27899.1 - 1.4 8.3 11.6 1.7 8.0 8.0 1.3 1 0 0 1 1 1 0 Spore coat protein CotO DUF2072 PF09845.4 EWM27899.1 - 3.1 7.7 10.9 4.9 7.0 7.6 1.3 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) RR_TM4-6 PF06459.7 EWM27899.1 - 3.4 7.4 14.8 3.9 7.3 10.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ycf1 PF05758.7 EWM27899.1 - 7.5 4.1 7.7 8.4 3.9 5.4 1.0 1 0 0 1 1 1 0 Ycf1 RRM_1 PF00076.17 EWM27900.1 - 6.3e-45 150.6 0.0 1.7e-15 56.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM27900.1 - 1.8e-28 98.3 0.0 9.7e-10 38.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM27900.1 - 1.8e-20 72.4 0.0 2.4e-08 33.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EWM27900.1 - 2.5e-05 24.0 0.0 0.00092 19.0 0.0 2.4 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 EWM27900.1 - 4.4e-05 23.1 0.1 0.00024 20.7 0.0 2.1 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EWM27900.1 - 0.0069 16.1 0.0 0.72 9.6 0.0 2.7 3 0 0 3 3 3 1 Limkain b1 Na_H_Exchanger PF00999.16 EWM27902.1 - 1.6e-48 165.1 45.7 2.1e-48 164.7 31.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family MIF4G PF02854.14 EWM27903.1 - 4.1e-34 117.8 0.0 1e-15 57.7 0.0 2.4 2 0 0 2 2 2 2 MIF4G domain Upf2 PF04050.9 EWM27903.1 - 3.4e-16 59.4 19.0 5.5e-16 58.8 13.2 1.3 1 0 0 1 1 1 1 Up-frameshift suppressor 2 CDC45 PF02724.9 EWM27903.1 - 0.071 11.1 6.6 0.092 10.7 4.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 EWM27903.1 - 0.096 11.1 21.9 0.15 10.5 15.2 1.2 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 EWM27903.1 - 0.2 9.5 18.7 0.34 8.7 13.0 1.3 1 0 0 1 1 1 0 Nop14-like family BSP_II PF05432.6 EWM27903.1 - 0.49 9.6 27.8 0.92 8.7 19.3 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF1510 PF07423.6 EWM27903.1 - 0.6 9.4 16.7 1 8.6 11.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2763 PF10961.3 EWM27903.1 - 0.62 10.4 6.4 2.7 8.4 4.5 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) F-protein PF00469.15 EWM27903.1 - 1.6 8.0 7.3 3 7.1 5.1 1.4 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Nucleoplasmin PF03066.10 EWM27903.1 - 1.7 8.1 18.3 3.3 7.2 12.7 1.5 1 0 0 1 1 1 0 Nucleoplasmin RNA_pol_3_Rpc31 PF11705.3 EWM27903.1 - 5.2 6.9 19.4 13 5.6 13.5 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DDHD PF02862.12 EWM27903.1 - 6.4 6.5 8.3 13 5.4 5.8 1.4 1 0 0 1 1 1 0 DDHD domain Ycf1 PF05758.7 EWM27903.1 - 7.1 4.2 7.5 9 3.8 5.2 1.1 1 0 0 1 1 1 0 Ycf1 Upf2 PF04050.9 EWM27904.1 - 2.4e-16 60.0 19.0 3.8e-16 59.3 13.2 1.3 1 0 0 1 1 1 1 Up-frameshift suppressor 2 MIF4G PF02854.14 EWM27904.1 - 3.1e-16 59.4 0.0 6.6e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 MIF4G domain CDC45 PF02724.9 EWM27904.1 - 0.064 11.2 6.8 0.079 10.9 4.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 EWM27904.1 - 0.069 11.6 21.9 0.11 11.0 15.2 1.2 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 EWM27904.1 - 0.15 9.9 18.8 0.26 9.1 13.0 1.3 1 0 0 1 1 1 0 Nop14-like family BSP_II PF05432.6 EWM27904.1 - 0.33 10.1 27.8 0.66 9.1 19.3 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) RXT2_N PF08595.6 EWM27904.1 - 0.46 10.2 6.8 1 9.1 4.7 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF1510 PF07423.6 EWM27904.1 - 0.48 9.7 16.9 0.85 8.9 11.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) F-protein PF00469.15 EWM27904.1 - 1.1 8.5 7.3 2.3 7.5 5.1 1.4 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Nucleoplasmin PF03066.10 EWM27904.1 - 1.2 8.6 18.4 2.5 7.5 12.7 1.5 1 0 0 1 1 1 0 Nucleoplasmin Ycf1 PF05758.7 EWM27904.1 - 5.4 4.5 7.6 6.7 4.2 5.2 1.1 1 0 0 1 1 1 0 Ycf1 YqfQ PF14181.1 EWM27904.1 - 8.3 6.4 10.9 19 5.2 7.6 1.6 1 0 0 1 1 1 0 YqfQ-like protein Zip PF02535.17 EWM27904.1 - 9.1 5.1 6.0 14 4.5 4.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DDHD PF02862.12 EWM27904.1 - 9.2 5.9 9.3 19 4.9 6.5 1.5 1 0 0 1 1 1 0 DDHD domain TRAP_alpha PF03896.11 EWM27904.1 - 9.6 5.1 13.4 16 4.3 9.3 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Pyr_redox_2 PF07992.9 EWM27905.1 - 4.9e-39 134.2 0.5 7.6e-39 133.6 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EWM27905.1 - 3.7e-28 97.7 0.0 7.3e-28 96.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EWM27905.1 - 1.6e-17 63.6 0.8 3.2e-14 53.0 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EWM27905.1 - 7.5e-11 42.4 0.5 1.9e-09 37.9 0.1 2.4 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EWM27905.1 - 1e-08 34.7 1.1 2.1e-07 30.4 0.7 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EWM27905.1 - 2e-06 26.5 0.9 0.061 11.7 0.6 3.2 3 0 0 3 3 3 3 HI0933-like protein GIDA PF01134.17 EWM27905.1 - 2e-06 26.9 0.4 1.2e-05 24.3 0.2 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A K_oxygenase PF13434.1 EWM27905.1 - 4.1e-06 25.9 0.0 3.9e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EWM27905.1 - 0.0044 15.9 4.0 0.0044 15.9 2.8 2.8 3 1 0 4 4 4 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 EWM27905.1 - 0.0044 16.1 0.0 1.9 7.5 0.0 2.5 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.12 EWM27905.1 - 0.024 13.7 0.2 0.054 12.5 0.1 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 EWM27905.1 - 0.031 14.0 1.3 1.6 8.5 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 EWM27905.1 - 0.036 14.3 0.1 1.6 9.0 0.1 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 EWM27905.1 - 0.037 13.6 1.8 1.2 8.7 0.0 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 EWM27905.1 - 0.098 11.4 10.6 0.038 12.8 3.1 2.8 3 0 0 3 3 3 0 FAD binding domain NAD_binding_8 PF13450.1 EWM27905.1 - 0.4 10.7 3.5 1.4 8.9 2.4 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain CBS PF00571.23 EWM27906.1 - 2.6e-08 33.4 0.0 3.9e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 CBS domain LRR_6 PF13516.1 EWM27907.1 - 2e-11 42.6 8.0 1.3 9.2 0.2 8.7 8 1 1 9 9 9 4 Leucine Rich repeat LRR_4 PF12799.2 EWM27907.1 - 9e-05 22.0 13.6 1.5 8.5 0.5 7.3 8 1 0 8 8 8 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EWM27907.1 - 0.048 13.4 16.1 0.99 9.2 0.3 5.5 6 1 0 6 6 6 0 Leucine rich repeat MiaE PF06175.6 EWM27907.1 - 0.16 11.2 0.1 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) LRR_1 PF00560.28 EWM27907.1 - 0.39 10.9 15.5 7.2 7.0 0.0 7.4 8 1 1 9 9 9 0 Leucine Rich Repeat LRR_7 PF13504.1 EWM27907.1 - 7.6 7.2 18.8 51 4.7 0.0 8.5 9 0 0 9 9 9 0 Leucine rich repeat AAA PF00004.24 EWM27908.1 - 7.3e-43 145.9 0.0 1.1e-42 145.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EWM27908.1 - 1.2e-05 26.0 0.1 4.2e-05 24.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EWM27908.1 - 3.9e-05 22.8 0.0 0.00012 21.1 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EWM27908.1 - 0.00014 22.0 0.2 0.0025 17.9 0.1 2.4 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 EWM27908.1 - 0.00014 21.3 0.0 0.00026 20.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 EWM27908.1 - 0.00037 19.9 0.8 0.0049 16.2 0.6 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EWM27908.1 - 0.00055 19.9 6.3 0.0049 16.8 0.0 3.1 2 2 0 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 EWM27908.1 - 0.00068 19.3 0.5 0.0026 17.4 0.0 2.3 2 0 0 2 2 1 1 Part of AAA domain AAA_5 PF07728.9 EWM27908.1 - 0.0011 18.7 0.2 0.013 15.2 0.1 2.8 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EWM27908.1 - 0.002 18.0 0.0 0.0048 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EWM27908.1 - 0.0021 16.8 0.0 0.0031 16.2 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 EWM27908.1 - 0.0039 16.3 0.4 0.013 14.7 0.0 1.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EWM27908.1 - 0.0042 17.3 0.0 0.025 14.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EWM27908.1 - 0.0046 16.9 0.7 0.039 13.9 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EWM27908.1 - 0.017 14.7 0.1 0.027 14.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 EWM27908.1 - 0.017 15.0 0.0 0.046 13.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 EWM27908.1 - 0.019 15.1 0.0 0.032 14.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.12 EWM27908.1 - 0.029 13.2 0.0 0.045 12.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.7 EWM27908.1 - 0.031 13.9 0.2 0.68 9.5 0.1 2.2 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.11 EWM27908.1 - 0.033 13.4 0.0 0.093 11.9 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein Zeta_toxin PF06414.7 EWM27908.1 - 0.035 13.1 0.0 0.064 12.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin KaiC PF06745.8 EWM27908.1 - 0.043 12.9 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.21 EWM27908.1 - 0.053 12.9 0.0 0.47 9.8 0.0 2.4 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_3 PF07726.6 EWM27908.1 - 0.11 12.1 0.0 0.28 10.7 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EWM27908.1 - 0.14 11.0 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) WD40_alt PF14077.1 EWM27908.1 - 0.16 11.5 1.4 0.36 10.5 1.0 1.5 1 0 0 1 1 1 0 Alternative WD40 repeat motif Pkinase PF00069.20 EWM27909.1 - 5.1e-31 107.7 0.0 1.2e-30 106.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM27909.1 - 3e-24 85.5 0.0 5.2e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EWM27909.1 - 0.0005 19.2 0.0 0.001 18.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EWM27909.1 - 0.0013 17.7 0.1 0.034 13.1 0.1 2.7 2 1 0 2 2 2 1 Kinase-like Chibby PF14645.1 EWM27909.1 - 0.0058 16.5 1.1 0.012 15.4 0.0 1.9 2 0 0 2 2 2 1 Chibby family TMF_TATA_bd PF12325.3 EWM27909.1 - 0.06 13.0 1.9 7.7 6.2 0.0 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding APH PF01636.18 EWM27909.1 - 0.068 12.8 0.1 0.068 12.8 0.1 3.1 2 2 1 3 3 3 0 Phosphotransferase enzyme family Spc7 PF08317.6 EWM27909.1 - 0.13 10.8 0.1 0.19 10.3 0.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein HOOK PF05622.7 EWM27909.1 - 4.4 4.9 8.7 2 6.0 4.2 1.5 1 1 0 1 1 1 0 HOOK protein DUF1995 PF09353.5 EWM27910.1 - 1.4e-21 77.1 0.0 3e-21 76.0 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1995) Med25 PF11232.3 EWM27910.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 25 PTOV activation and synapsin 2 SRPRB PF09439.5 EWM27910.1 - 0.18 11.0 0.1 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Voltage_CLC PF00654.15 EWM27911.1 - 0.0014 17.7 1.1 0.17 10.8 0.0 2.1 1 1 1 2 2 2 2 Voltage gated chloride channel LCE PF14672.1 EWM27911.1 - 0.028 14.9 3.6 0.068 13.6 2.5 1.7 1 0 0 1 1 1 0 Late cornified envelope SR-25 PF10500.4 EWM27911.1 - 0.044 13.2 8.7 0.066 12.6 6.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CytochromB561_N PF09786.4 EWM27911.1 - 0.32 9.4 7.3 0.45 8.9 5.1 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Tmemb_55A PF09788.4 EWM27912.1 - 0.041 12.9 4.4 0.053 12.6 2.7 1.4 1 1 0 1 1 1 0 Transmembrane protein 55A DUF3797 PF12677.2 EWM27912.1 - 0.078 12.6 2.2 0.52 9.9 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) zf-LSD1 PF06943.7 EWM27912.1 - 0.11 12.1 0.1 0.11 12.1 0.1 2.0 2 0 0 2 2 2 0 LSD1 zinc finger Hist_deacetyl PF00850.14 EWM27914.1 - 1.2e-82 277.6 0.0 1.6e-82 277.2 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain DUF4119 PF13494.1 EWM27914.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF4119) ECH PF00378.15 EWM27915.1 - 5.8e-58 195.8 0.2 7.3e-58 195.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EWM27915.1 - 0.1 12.7 0.1 0.77 9.9 0.0 2.1 2 0 0 2 2 2 0 2-enoyl-CoA Hydratase C-terminal region DUF647 PF04884.9 EWM27916.1 - 1.1e-78 263.8 1.0 1.5e-78 263.4 0.7 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis AAA_33 PF13671.1 EWM27917.1 - 6.1e-05 22.9 0.1 0.00037 20.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain ABC2_membrane PF01061.19 EWM27919.1 - 4.2e-28 97.9 25.8 6.2e-28 97.3 17.9 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EWM27919.1 - 1.2e-18 67.6 0.0 2e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EWM27919.1 - 6.6e-12 45.9 0.0 4.6e-06 26.8 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EWM27919.1 - 0.00013 22.3 0.1 0.00022 21.6 0.1 1.3 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 EWM27919.1 - 0.00028 20.1 0.0 0.53 9.4 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.2 EWM27919.1 - 0.00064 18.8 26.3 0.0018 17.4 18.2 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_15 PF13175.1 EWM27919.1 - 0.00066 18.8 0.1 0.11 11.5 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EWM27919.1 - 0.0014 18.1 0.1 0.004 16.6 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EWM27919.1 - 0.0043 16.2 0.0 0.0076 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EWM27919.1 - 0.006 16.7 0.1 0.082 13.0 0.0 2.6 2 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EWM27919.1 - 0.0089 16.0 0.1 0.023 14.6 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EWM27919.1 - 0.02 14.3 0.4 0.045 13.1 0.3 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EWM27919.1 - 0.061 13.0 0.1 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_10 PF12846.2 EWM27919.1 - 0.077 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_13 PF13166.1 EWM27919.1 - 0.16 10.4 0.2 0.98 7.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.4 EWM27919.1 - 0.19 10.2 0.3 0.3 9.6 0.2 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class PPR_2 PF13041.1 EWM27920.1 - 1.6e-35 120.8 0.7 2.4e-07 30.5 0.0 9.5 6 2 4 10 10 10 7 PPR repeat family PPR PF01535.15 EWM27920.1 - 2.1e-31 105.7 17.3 3.3e-05 23.5 0.1 11.8 12 0 0 12 12 12 6 PPR repeat PPR_3 PF13812.1 EWM27920.1 - 3.4e-26 89.2 17.8 0.0038 17.3 0.0 12.0 13 0 0 13 13 12 7 Pentatricopeptide repeat domain PPR_1 PF12854.2 EWM27920.1 - 3.3e-11 42.4 0.0 0.05 13.0 0.0 7.1 8 0 0 8 8 8 3 PPR repeat TPR_12 PF13424.1 EWM27920.1 - 0.00016 21.5 5.6 6.2 6.8 0.0 6.6 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 EWM27920.1 - 0.00016 21.9 4.1 31 4.9 0.0 6.6 6 1 0 7 7 7 0 Tetratricopeptide repeat Apc3 PF12895.2 EWM27920.1 - 0.00042 20.3 0.0 4.9 7.3 0.0 4.3 3 2 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EWM27920.1 - 0.009 15.7 4.6 12 5.9 0.0 5.3 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 EWM27920.1 - 0.011 16.3 27.0 9.1 7.2 0.0 10.4 10 2 1 11 11 10 0 Tetratricopeptide repeat TPR_6 PF13174.1 EWM27920.1 - 0.03 14.7 2.9 88 3.8 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 EWM27920.1 - 0.032 14.1 2.6 23 5.1 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 EWM27920.1 - 0.46 10.4 11.8 1.6 8.7 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Methyltransf_11 PF08241.7 EWM27921.1 - 3.1e-12 46.7 0.0 8.3e-12 45.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM27921.1 - 1.4e-05 24.6 0.0 2.2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM27921.1 - 4.4e-05 23.2 0.0 0.00011 21.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM27921.1 - 6.8e-05 23.2 0.0 0.00015 22.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EWM27921.1 - 0.00053 19.1 0.0 0.00074 18.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EWM27921.1 - 0.0012 19.2 0.0 0.0028 17.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 EWM27921.1 - 0.014 13.7 0.0 0.019 13.3 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.10 EWM27921.1 - 0.056 13.0 0.1 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_18 PF12847.2 EWM27921.1 - 0.12 12.9 0.0 0.23 12.0 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain SNARE PF05739.14 EWM27922.1 - 9.6e-14 50.8 2.8 9.6e-14 50.8 1.9 2.9 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EWM27922.1 - 8.4e-09 35.5 2.2 3.6e-07 30.2 0.1 2.3 2 0 0 2 2 2 2 Syntaxin Baculo_PEP_C PF04513.7 EWM27922.1 - 0.59 9.9 2.4 5.8 6.7 0.2 2.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 EWM27922.1 - 3.1 8.1 6.7 62 3.9 0.1 3.8 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Methyltransf_8 PF05148.10 EWM27923.1 - 1.2e-63 214.7 0.2 3e-62 210.1 0.0 2.6 2 1 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 EWM27923.1 - 0.0003 21.1 0.1 0.00055 20.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Mei4 PF13971.1 EWM27924.1 - 0.43 9.4 1.2 0.65 8.8 0.8 1.2 1 0 0 1 1 1 0 Meiosis-specific protein Mei4 PKD_channel PF08016.7 EWM27927.1 - 5.2e-08 31.7 4.3 1e-07 30.7 3.0 1.5 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 EWM27927.1 - 0.28 10.4 16.9 1.7 7.8 11.7 2.1 1 1 0 1 1 1 0 Ion transport protein MS_channel PF00924.13 EWM27928.1 - 1e-20 73.9 4.4 1.3e-20 73.6 1.6 1.9 2 0 0 2 2 2 1 Mechanosensitive ion channel PTS_EIIC_2 PF13303.1 EWM27928.1 - 0.56 8.9 7.7 0.24 10.1 3.8 1.4 2 0 0 2 2 2 0 Phosphotransferase system, EIIC COPIIcoated_ERV PF07970.7 EWM27929.1 - 2.8e-29 102.3 0.0 3.9e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EWM27929.1 - 8.1e-18 64.1 0.9 1.7e-17 63.1 0.0 1.9 3 0 0 3 3 3 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Abhydrolase_5 PF12695.2 EWM27930.1 - 1.5e-10 41.0 0.0 3.1e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EWM27930.1 - 1.5e-10 41.3 1.4 4.4e-10 39.8 1.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family IBR PF01485.16 EWM27931.1 - 0.12 12.2 0.2 0.2 11.5 0.0 1.3 2 0 0 2 2 2 0 IBR domain UxaC PF02614.9 EWM27932.1 - 1e-96 324.3 0.0 1.8e-96 323.5 0.0 1.3 1 1 0 1 1 1 1 Glucuronate isomerase Mannitol_dh_C PF08125.8 EWM27932.1 - 1.1e-05 24.6 0.0 0.00087 18.5 0.0 2.3 2 0 0 2 2 2 2 Mannitol dehydrogenase C-terminal domain OsmC PF02566.14 EWM27933.1 - 9e-15 54.6 0.0 1.4e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein LRRNT PF01462.13 EWM27933.1 - 0.15 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain SF-assemblin PF06705.6 EWM27934.1 - 8.8e-41 139.6 21.6 1e-40 139.4 15.0 1.0 1 0 0 1 1 1 1 SF-assemblin/beta giardin GP41 PF00517.12 EWM27934.1 - 0.071 12.6 2.2 0.11 12.0 0.1 2.2 2 1 1 3 3 3 0 Retroviral envelope protein DUF2262 PF10020.4 EWM27934.1 - 0.087 13.0 4.4 3.1 8.0 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2262) T2SF PF00482.18 EWM27934.1 - 0.11 12.3 4.9 0.28 11.1 3.4 1.7 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F HK97-gp10_like PF04883.7 EWM27934.1 - 0.12 13.3 2.6 4.1 8.3 0.4 2.8 2 1 1 3 3 3 0 Bacteriophage HK97-gp10, putative tail-component TPR_11 PF13414.1 EWM27935.1 - 6e-21 73.8 6.8 5.7e-18 64.3 2.4 2.5 1 1 0 2 2 2 2 TPR repeat Prefoldin_2 PF01920.15 EWM27935.1 - 1.4e-15 56.9 0.7 1.4e-15 56.9 0.5 2.1 2 0 0 2 2 2 1 Prefoldin subunit TPR_1 PF00515.23 EWM27935.1 - 6e-11 41.4 6.4 1.3e-06 27.7 0.3 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EWM27935.1 - 7.1e-11 41.1 13.3 2.4e-06 27.0 0.3 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EWM27935.1 - 8.6e-09 35.2 6.1 0.0004 20.7 0.1 4.1 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EWM27935.1 - 5.5e-08 33.2 9.8 3.2e-05 24.4 0.6 3.4 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 EWM27935.1 - 4.2e-06 27.0 3.4 0.015 15.5 0.3 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EWM27935.1 - 1.6e-05 24.7 3.4 0.44 10.8 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 EWM27935.1 - 0.00059 19.6 1.4 0.28 11.0 0.2 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 EWM27935.1 - 0.00077 19.7 4.9 0.38 11.3 0.0 3.5 4 0 0 4 4 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EWM27935.1 - 0.0012 18.6 1.5 0.0031 17.3 0.2 2.2 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.1 EWM27935.1 - 0.0014 18.2 1.0 2.1 8.3 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EWM27935.1 - 0.0029 17.2 3.6 0.63 9.9 0.3 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TOM20_plant PF06552.7 EWM27935.1 - 0.012 15.1 1.1 1.3 8.6 0.1 2.2 1 1 1 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_12 PF13424.1 EWM27935.1 - 0.034 14.0 9.2 0.78 9.7 1.6 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat SlyX PF04102.7 EWM27935.1 - 0.53 10.7 4.4 5.8 7.3 0.0 3.3 3 0 0 3 3 3 0 SlyX IncA PF04156.9 EWM27935.1 - 0.55 9.8 4.9 0.6 9.6 2.6 1.6 1 1 0 1 1 1 0 IncA protein SH3BP5 PF05276.9 EWM27935.1 - 1.5 8.0 11.7 0.035 13.4 1.3 2.5 2 1 1 3 3 3 0 SH3 domain-binding protein 5 (SH3BP5) COQ9 PF08511.6 EWM27936.1 - 6.7e-21 73.5 0.0 1.3e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 COQ9 T4_tail_cap PF11091.3 EWM27936.1 - 0.042 12.5 0.8 0.079 11.6 0.1 1.7 2 0 0 2 2 2 0 Tail-tube assembly protein Trypsin_2 PF13365.1 EWM27937.1 - 4.8e-22 78.2 1.4 7.9e-22 77.4 1.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 EWM27937.1 - 3e-17 62.9 0.1 4.3e-17 62.4 0.1 1.2 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.1 EWM27937.1 - 1.7e-13 50.2 0.0 3.3e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 EWM27937.1 - 2.8e-08 33.8 0.0 7.3e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Peptidase_S46 PF10459.4 EWM27937.1 - 3.1e-06 25.9 1.2 0.035 12.5 0.1 2.1 2 0 0 2 2 2 2 Peptidase S46 GRASP55_65 PF04495.9 EWM27937.1 - 0.0032 17.4 0.0 0.0057 16.6 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain Peptidase_S32 PF05579.8 EWM27937.1 - 0.018 14.0 1.9 1.2 7.9 1.3 2.2 1 1 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Tricorn_PDZ PF14685.1 EWM27937.1 - 0.027 14.2 0.0 0.075 12.8 0.0 1.7 1 0 0 1 1 1 0 Tricorn protease PDZ domain MreC PF04085.9 EWM27937.1 - 0.057 12.8 0.1 0.13 11.6 0.1 1.6 1 0 0 1 1 1 0 rod shape-determining protein MreC LSM PF01423.17 EWM27937.1 - 0.066 12.7 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 LSM domain Peptidase_S7 PF00949.16 EWM27937.1 - 0.12 11.7 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease SET PF00856.23 EWM27938.1 - 6.1e-09 36.3 0.0 0.00041 20.6 0.0 2.2 2 1 0 2 2 2 2 SET domain zf-MYND PF01753.13 EWM27938.1 - 0.00045 20.0 2.3 0.00045 20.0 1.6 2.2 2 0 0 2 2 2 1 MYND finger TPIP1 PF15338.1 EWM27938.1 - 0.053 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 p53-regulated apoptosis-inducing protein 1 CCT PF06203.9 EWM27939.1 - 0.0035 16.9 9.7 0.009 15.6 6.7 1.7 1 1 0 1 1 1 1 CCT motif Pyr_redox_2 PF07992.9 EWM27940.1 - 4.5e-18 65.8 0.0 1.3e-17 64.3 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EWM27940.1 - 5.9e-11 42.6 0.3 9.8e-10 38.7 0.2 2.9 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase MIR PF02815.14 EWM27941.1 - 2.4e-12 46.7 0.3 2.8e-07 30.2 0.0 3.0 1 1 2 3 3 3 3 MIR domain Ins145_P3_rec PF08709.6 EWM27941.1 - 0.018 14.0 0.0 1.8 7.5 0.1 2.8 1 1 1 2 2 2 0 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.14 EWM27942.1 - 2e-12 47.0 0.1 5e-07 29.4 0.0 3.1 1 1 2 3 3 3 3 MIR domain Ins145_P3_rec PF08709.6 EWM27942.1 - 0.0027 16.7 0.0 0.19 10.7 0.0 2.8 1 1 0 2 2 2 2 Inositol 1,4,5-trisphosphate/ryanodine receptor NUDIX PF00293.23 EWM27943.1 - 4.3e-11 42.5 0.2 7.8e-11 41.7 0.2 1.4 1 0 0 1 1 1 1 NUDIX domain Pro_isomerase PF00160.16 EWM27946.1 - 3.2e-12 46.9 0.0 5.6e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RHD3 PF05879.7 EWM27948.1 - 0.00036 18.6 0.5 0.00047 18.2 0.4 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GMC_oxred_N PF00732.14 EWM27948.1 - 0.02 14.0 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 GMC oxidoreductase Lge1 PF11488.3 EWM27948.1 - 0.029 14.5 0.7 0.44 10.7 0.3 2.5 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 Activator_LAG-3 PF11498.3 EWM27948.1 - 0.94 8.1 12.4 1.5 7.5 8.6 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Epimerase PF01370.16 EWM27949.1 - 1.5e-21 76.9 0.0 3.4e-21 75.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EWM27949.1 - 3.2e-18 65.4 0.0 5.1e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EWM27949.1 - 5.6e-12 45.1 0.0 1.2e-11 44.0 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EWM27949.1 - 7.3e-08 31.6 0.0 3.7e-05 22.7 0.0 2.2 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EWM27949.1 - 3.6e-06 26.0 0.1 4.1e-05 22.6 0.1 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EWM27949.1 - 4e-06 26.8 0.6 3.4e-05 23.8 0.4 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EWM27949.1 - 0.0033 17.0 0.1 0.011 15.3 0.1 1.8 1 1 0 1 1 1 1 KR domain PPR_3 PF13812.1 EWM27950.1 - 3.7e-16 57.9 0.1 0.00017 21.5 0.0 4.0 3 0 0 3 3 3 3 Pentatricopeptide repeat domain PPR_2 PF13041.1 EWM27950.1 - 1.6e-13 50.4 0.0 3.1e-05 23.8 0.0 3.8 3 1 1 4 4 4 3 PPR repeat family PPR PF01535.15 EWM27950.1 - 1.3e-08 34.2 0.0 0.003 17.4 0.0 4.0 3 1 0 3 3 3 3 PPR repeat RNase_Zc3h12a PF11977.3 EWM27950.1 - 7.1e-06 25.9 0.0 1.3e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain PPR_1 PF12854.2 EWM27950.1 - 5.5e-05 22.5 0.0 0.0034 16.8 0.0 3.1 3 0 0 3 3 3 1 PPR repeat TF_Zn_Ribbon PF08271.7 EWM27950.1 - 0.16 11.2 0.1 0.33 10.3 0.1 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding TPR_14 PF13428.1 EWM27950.1 - 0.77 10.5 10.5 5.8 7.8 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Reo_sigmaC PF04582.7 EWM27951.1 - 4.6 6.3 15.5 4.3 6.4 0.0 5.0 4 1 1 5 5 5 0 Reovirus sigma C capsid protein ABC1 PF03109.11 EWM27952.1 - 1.6e-28 99.0 0.0 4.9e-28 97.4 0.0 1.9 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 EWM27952.1 - 0.00037 20.3 0.3 0.0011 18.7 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 EWM27952.1 - 0.011 14.9 0.0 2.2 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain EF-hand_8 PF13833.1 EWM27953.1 - 1.1e-23 82.5 4.8 4.7e-13 48.5 0.6 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.1 EWM27953.1 - 2.9e-21 75.3 1.7 1e-09 38.3 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EWM27953.1 - 6e-18 62.7 6.5 8e-08 31.0 0.3 4.4 4 1 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EWM27953.1 - 4.3e-17 60.3 4.4 8.2e-06 25.2 0.1 4.1 3 1 1 4 4 4 3 EF-hand domain EF-hand_9 PF14658.1 EWM27953.1 - 5.7e-12 45.3 0.1 1e-08 34.9 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 EWM27953.1 - 2e-09 36.3 3.9 0.00021 20.4 0.1 3.8 3 1 0 3 3 3 2 EF hand EF-hand_4 PF12763.2 EWM27953.1 - 0.00027 20.6 0.1 0.42 10.3 0.0 2.2 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.8 EWM27953.1 - 0.016 14.7 0.0 3.8 7.0 0.0 2.2 2 0 0 2 2 2 0 Caleosin related protein DUF3008 PF11450.3 EWM27953.1 - 0.082 13.0 0.4 0.2 11.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknwon function (DUF3008) Glycos_transf_1 PF00534.15 EWM27954.1 - 2.1e-25 89.1 0.0 3.3e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EWM27954.1 - 6.3e-16 58.7 0.2 2.4e-14 53.6 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EWM27954.1 - 8e-08 32.5 0.0 3.6e-07 30.4 0.0 2.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 EWM27954.1 - 2.8e-05 23.8 0.0 6.2e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.1 EWM27954.1 - 0.00012 22.2 0.2 0.00032 20.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 GSDH PF07995.6 EWM27955.1 - 1.1e-24 87.1 0.0 4.1e-24 85.2 0.0 1.9 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase IL17 PF06083.6 EWM27955.1 - 0.078 13.0 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 Interleukin-17 DinB_2 PF12867.2 EWM27956.1 - 0.00011 22.5 0.0 0.00029 21.1 0.0 1.8 1 0 0 1 1 1 1 DinB superfamily Mif2_N PF15624.1 EWM27956.1 - 0.00047 20.7 4.2 0.00047 20.7 2.9 3.7 3 1 0 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.3 EWM27956.1 - 0.0029 17.5 0.0 0.12 12.4 0.0 2.5 2 0 0 2 2 2 1 Mif2/CENP-C like Cupin_2 PF07883.6 EWM27956.1 - 0.0077 15.7 0.0 0.046 13.2 0.0 2.4 2 0 0 2 2 2 1 Cupin domain Ribosomal_L3 PF00297.17 EWM27957.1 - 1.1e-38 133.2 0.4 4.7e-38 131.1 0.3 1.8 1 1 0 1 1 1 1 Ribosomal protein L3 SYS1 PF09801.4 EWM27958.1 - 1.3e-41 141.9 1.4 1.5e-41 141.7 1.0 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network FA_desaturase PF00487.19 EWM27958.1 - 8.4 5.7 8.4 15 4.9 5.7 1.5 1 1 0 1 1 1 0 Fatty acid desaturase Med26 PF08711.6 EWM27959.1 - 0.0008 18.8 0.4 0.0017 17.8 0.3 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain GRIM-19 PF06212.7 EWM27959.1 - 0.071 12.8 0.2 0.85 9.3 0.1 2.4 2 0 0 2 2 2 0 GRIM-19 protein RasGEF_N PF00618.15 EWM27959.1 - 0.073 13.1 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 RasGEF N-terminal motif zf-CCCH PF00642.19 EWM27959.1 - 0.36 10.5 8.2 0.053 13.2 2.8 1.8 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EWM27959.1 - 1.6 8.8 6.9 0.15 12.0 0.8 2.2 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type NMD3 PF04981.8 EWM27960.1 - 2.5e-48 164.2 0.1 3.7e-48 163.6 0.1 1.3 1 0 0 1 1 1 1 NMD3 family Yippee-Mis18 PF03226.9 EWM27960.1 - 0.035 14.1 0.0 0.093 12.7 0.0 1.8 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly CTD_bind PF04818.8 EWM27961.1 - 1.1e-10 41.6 0.0 2.2e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CTD_bind PF04818.8 EWM27962.1 - 1e-10 41.6 0.0 2.1e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. eIF-1a PF01176.14 EWM27963.1 - 2.4e-29 100.5 0.7 3.3e-29 100.0 0.5 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 eIF-1a PF01176.14 EWM27964.1 - 2.4e-29 100.5 0.7 3.3e-29 100.0 0.5 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Abhydrolase_6 PF12697.2 EWM27965.1 - 5.7e-05 23.1 2.7 0.00011 22.2 1.8 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 EWM27965.1 - 0.00018 20.8 0.4 0.00067 19.0 0.2 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.2 EWM27965.1 - 0.015 15.0 5.1 0.037 13.7 3.5 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.15 EWM27965.1 - 0.029 14.6 1.6 0.061 13.5 1.1 1.5 1 0 0 1 1 1 0 Thioesterase domain Ser_hydrolase PF06821.8 EWM27965.1 - 0.06 12.9 5.8 0.11 12.0 4.1 1.4 1 0 0 1 1 1 0 Serine hydrolase Tis11B_N PF04553.7 EWM27965.1 - 0.088 12.9 0.1 0.33 11.1 0.1 2.0 1 0 0 1 1 1 0 Tis11B like protein, N terminus Lipase_3 PF01764.20 EWM27965.1 - 0.18 11.4 0.4 0.43 10.1 0.0 1.8 2 0 0 2 2 2 0 Lipase (class 3) PsbW PF07123.7 EWM27965.1 - 3.6 7.6 16.0 8.7 6.4 11.1 1.6 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) Abhydrolase_6 PF12697.2 EWM27967.1 - 7.9e-14 52.0 0.0 1.6e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM27967.1 - 5.3e-06 26.2 0.0 8.5e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EWM27967.1 - 0.0064 16.0 0.0 0.094 12.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EWM27967.1 - 0.038 13.4 0.1 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 Putative esterase DUF2892 PF11127.3 EWM27967.1 - 0.075 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) NUDIX PF00293.23 EWM27968.1 - 1.1e-09 38.0 0.3 2.2e-09 37.0 0.1 1.7 2 0 0 2 2 2 1 NUDIX domain BNR_2 PF13088.1 EWM27969.1 - 0.094 11.9 0.0 0.095 11.9 0.0 1.0 1 0 0 1 1 1 0 BNR repeat-like domain HABP4_PAI-RBP1 PF04774.10 EWM27970.1 - 2.5e-09 37.6 17.2 2.5e-09 37.6 11.9 3.7 3 1 1 4 4 4 1 Hyaluronan / mRNA binding family Strep_SA_rep PF06696.6 EWM27970.1 - 0.18 11.5 0.8 0.28 11.0 0.5 1.2 1 0 0 1 1 1 0 Streptococcal surface antigen repeat DUF3292 PF11696.3 EWM27970.1 - 0.21 9.3 1.0 0.27 9.0 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Nucleoplasmin PF03066.10 EWM27971.1 - 0.017 14.6 0.6 0.018 14.5 0.4 1.2 1 0 0 1 1 1 0 Nucleoplasmin BUD22 PF09073.5 EWM27971.1 - 0.062 12.3 1.5 0.071 12.1 1.0 1.0 1 0 0 1 1 1 0 BUD22 PBP1_TM PF14812.1 EWM27971.1 - 0.15 12.4 3.3 0.28 11.5 2.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Paf1 PF03985.8 EWM27971.1 - 0.94 8.1 3.4 1.2 7.8 2.4 1.1 1 0 0 1 1 1 0 Paf1 DUF1118 PF06549.7 EWM27972.1 - 1.7e-06 28.1 7.1 1.7e-06 28.1 4.9 2.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1118) DUF1499 PF07386.6 EWM27973.1 - 1.2e-07 31.9 0.0 2.2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1499) RelA_SpoT PF04607.12 EWM27974.1 - 1.5e-23 82.9 0.0 4.7e-23 81.3 0.0 1.8 1 1 0 1 1 1 1 Region found in RelA / SpoT proteins HD_4 PF13328.1 EWM27974.1 - 5.6e-10 39.1 0.2 1e-09 38.2 0.1 1.4 1 0 0 1 1 1 1 HD domain CaM_binding PF07839.6 EWM27974.1 - 0.028 14.6 0.0 0.065 13.4 0.0 1.6 1 0 0 1 1 1 0 Plant calmodulin-binding domain Proteasome_A_N PF10584.4 EWM27974.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature TGS PF02824.16 EWM27974.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 TGS domain COX15-CtaA PF02628.10 EWM27976.1 - 2.6e-92 308.9 14.8 1.4e-91 306.5 10.3 1.8 1 1 0 1 1 1 1 Cytochrome oxidase assembly protein CReP_N PF10472.4 EWM27976.1 - 0.13 10.9 0.4 0.22 10.2 0.3 1.3 1 0 0 1 1 1 0 eIF2-alpha phosphatase phosphorylation constitutive repressor CTP_transf_1 PF01148.15 EWM27977.1 - 1.3e-59 201.9 25.7 2.8e-59 200.8 17.8 1.5 1 1 0 1 1 1 1 Cytidylyltransferase family SNAP PF14938.1 EWM27979.1 - 0.004 16.3 0.0 0.0067 15.6 0.0 1.3 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.1 EWM27979.1 - 0.0061 16.2 2.4 0.026 14.3 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EWM27979.1 - 0.012 15.5 0.3 0.17 11.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 EWM27979.1 - 0.016 15.0 3.2 0.04 13.8 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EWM27979.1 - 0.026 14.4 1.9 1.6 8.8 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EWM27979.1 - 0.18 12.5 7.7 4.2 8.2 0.5 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Lipase_3 PF01764.20 EWM27980.1 - 8e-18 64.4 0.0 2.4e-17 62.8 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EWM27980.1 - 1.6e-05 24.9 0.8 0.00028 20.8 0.0 2.9 3 0 0 3 3 3 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EWM27980.1 - 3.7e-05 23.4 0.0 6.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF2974 PF11187.3 EWM27980.1 - 0.002 17.5 0.1 0.65 9.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 EWM27980.1 - 0.0064 16.2 0.0 0.015 15.0 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EWM27980.1 - 0.17 11.1 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EWM27981.1 - 9.6e-36 123.7 0.1 1.7e-35 123.0 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM27981.1 - 2e-20 73.0 0.0 8.6e-19 67.7 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EWM27981.1 - 3.2e-08 33.3 0.0 6.2e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EWM27981.1 - 6.5e-08 32.4 0.0 5e-06 26.2 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EWM27981.1 - 0.0069 16.6 0.0 0.021 15.0 0.0 2.0 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_4 PF08386.5 EWM27981.1 - 0.018 14.9 0.0 0.064 13.1 0.0 1.8 2 0 0 2 2 2 0 TAP-like protein DLH PF01738.13 EWM27981.1 - 0.019 14.2 0.0 0.46 9.7 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF2305 PF10230.4 EWM27981.1 - 0.019 14.3 0.0 2.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Peptidase_S9 PF00326.16 EWM27981.1 - 0.025 13.8 0.0 0.23 10.6 0.0 2.4 2 1 0 2 2 2 0 Prolyl oligopeptidase family UPF0227 PF05728.7 EWM27981.1 - 0.03 14.0 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) SLT_L PF14718.1 EWM27981.1 - 0.074 12.8 0.1 0.74 9.6 0.0 2.3 2 0 0 2 2 2 0 Soluble lytic murein transglycosylase L domain Abhydrolase_2 PF02230.11 EWM27981.1 - 0.17 11.3 0.0 4.9 6.5 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Ldh_1_N PF00056.18 EWM27982.1 - 1.6e-28 99.2 0.1 2.6e-28 98.6 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EWM27982.1 - 9e-17 61.3 0.2 3.5e-16 59.4 0.1 2.0 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain CofC PF01983.11 EWM27982.1 - 0.11 11.4 0.0 0.32 9.9 0.0 1.7 2 0 0 2 2 2 0 Guanylyl transferase CofC like 2TM PF13239.1 EWM27983.1 - 0.0068 16.4 8.5 0.015 15.3 5.9 1.6 1 0 0 1 1 1 1 2TM domain Fe_bilin_red PF05996.7 EWM27984.1 - 6.4e-51 173.0 0.0 7.8e-51 172.7 0.0 1.1 1 0 0 1 1 1 1 Ferredoxin-dependent bilin reductase RRP7 PF12923.2 EWM27985.1 - 4.1e-33 114.1 15.3 4.1e-33 114.1 10.6 1.8 1 1 1 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) AAA_23 PF13476.1 EWM27985.1 - 0.0031 17.8 1.8 0.0046 17.3 1.2 1.2 1 0 0 1 1 1 1 AAA domain RRM_6 PF14259.1 EWM27985.1 - 0.057 13.3 0.1 0.88 9.5 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF4404 PF14357.1 EWM27985.1 - 0.64 10.4 8.0 0.24 11.8 1.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Ribosomal_L21p PF00829.16 EWM27986.1 - 1.4e-24 86.0 3.3 1.8e-24 85.6 2.3 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein DUF2930 PF11152.3 EWM27987.1 - 1.3e-31 109.2 0.0 1.7e-31 108.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2930) GerE PF00196.14 EWM27987.1 - 0.11 11.8 0.0 0.39 10.0 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family DUF1768 PF08719.6 EWM27988.1 - 1.2e-24 86.7 0.1 2.2e-24 86.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) RRM_6 PF14259.1 EWM27988.1 - 7e-15 54.7 0.0 2.8e-14 52.8 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EWM27988.1 - 1.4e-11 43.7 0.0 3.6e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FHA PF00498.21 EWM27988.1 - 4e-08 33.2 0.0 7.2e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain Pyridoxal_deC PF00282.14 EWM27989.1 - 7.1e-19 67.4 0.0 1.6e-18 66.3 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EWM27989.1 - 2.2e-07 29.9 0.0 3.6e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DUF4530 PF15039.1 EWM27989.1 - 0.14 12.0 6.6 0.19 11.6 2.9 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4530) Pkinase PF00069.20 EWM27991.1 - 2.2e-45 154.8 0.0 2.6e-31 108.7 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EWM27991.1 - 3.8e-33 114.6 0.0 3.5e-16 59.0 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.1 EWM27991.1 - 0.00021 20.3 0.0 0.00061 18.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like GCV_T PF01571.16 EWM27992.1 - 2.6e-12 46.5 0.0 4.3e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EWM27992.1 - 0.00023 21.1 0.0 0.0043 17.0 0.0 2.3 1 1 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DUF4033 PF13225.1 EWM27994.1 - 1e-24 85.9 0.1 2e-24 85.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4033) NAD_binding_2 PF03446.10 EWM27995.1 - 4.8e-46 156.5 3.2 7.1e-46 156.0 2.2 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EWM27995.1 - 7.7e-38 129.2 0.0 1.5e-37 128.3 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.14 EWM27995.1 - 5.5e-11 41.9 0.4 1.4e-10 40.6 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EWM27995.1 - 6.5e-08 32.8 0.0 1.4e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 EWM27995.1 - 0.00013 21.3 0.0 0.00026 20.4 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EWM27995.1 - 0.00068 19.6 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.13 EWM27995.1 - 0.0028 17.3 0.4 0.0057 16.3 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EWM27995.1 - 0.023 14.1 1.3 0.25 10.7 0.0 2.6 2 1 1 3 3 3 0 Ketopantoate reductase PanE/ApbA FHA PF00498.21 EWM27996.1 - 1.4e-12 47.5 0.1 3.4e-12 46.3 0.1 1.6 1 0 0 1 1 1 1 FHA domain RINGv PF12906.2 EWM27996.1 - 7e-11 42.0 6.5 1.4e-10 41.0 4.5 1.6 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EWM27996.1 - 0.027 14.3 4.3 0.074 12.9 3.0 1.8 1 1 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.1 EWM27996.1 - 4.1 7.1 6.2 11 5.7 4.3 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ABC_tran PF00005.22 EWM27997.1 - 3.2e-33 114.9 0.0 5.6e-33 114.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EWM27997.1 - 2.9e-31 108.9 15.1 5.4e-31 108.0 10.5 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EWM27997.1 - 0.0016 17.6 0.1 0.88 8.7 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain MENTAL PF10457.4 EWM27997.1 - 0.0019 17.8 0.9 0.0041 16.7 0.6 1.5 1 0 0 1 1 1 1 Cholesterol-capturing domain AAA_16 PF13191.1 EWM27997.1 - 0.0031 17.5 1.8 0.013 15.5 0.7 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 EWM27997.1 - 0.0035 17.3 0.1 0.26 11.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EWM27997.1 - 0.0048 16.3 0.2 1.3 8.3 0.1 2.4 2 0 0 2 2 2 1 AAA-like domain AAA_29 PF13555.1 EWM27997.1 - 0.0099 15.3 0.1 0.044 13.3 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 EWM27997.1 - 0.014 14.5 0.0 0.032 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 EWM27997.1 - 0.018 14.7 0.0 0.047 13.3 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EWM27997.1 - 0.02 14.8 0.1 0.061 13.2 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF87 PF01935.12 EWM27997.1 - 0.022 14.5 0.0 0.24 11.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_17 PF13207.1 EWM27997.1 - 0.04 14.7 0.0 0.094 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EWM27997.1 - 0.055 13.9 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein DUF4351 PF14261.1 EWM27997.1 - 0.057 13.3 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) AAA_25 PF13481.1 EWM27997.1 - 0.061 12.7 0.0 0.24 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EWM27997.1 - 0.091 12.8 0.1 0.94 9.6 0.1 2.3 1 1 0 1 1 1 0 AAA domain 2-oxoacid_dh PF00198.18 EWM27998.1 - 1.5e-60 204.3 0.0 1.8e-60 204.0 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EWM27998.1 - 1.1e-15 56.9 0.4 2.2e-15 56.0 0.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EWM27998.1 - 2.2e-13 49.5 0.4 5.5e-13 48.3 0.3 1.7 1 0 0 1 1 1 1 e3 binding domain ARS2 PF04959.8 EWM27998.1 - 0.031 14.4 0.7 1.5 8.9 0.3 2.3 2 0 0 2 2 2 0 Arsenite-resistance protein 2 IQ PF00612.22 EWM27999.1 - 0.0019 17.6 7.7 0.003 17.0 1.2 2.6 2 0 0 2 2 2 2 IQ calmodulin-binding motif DUF4463 PF14703.1 EWM28000.1 - 0.17 12.4 0.0 0.17 12.4 0.0 7.0 8 0 0 8 8 8 0 Domain of unknown function (DUF4463) DUF1336 PF07059.7 EWM28001.1 - 6e-42 143.5 0.0 8e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) Biopterin_H PF00351.16 EWM28002.1 - 4.9e-127 423.2 0.0 1.3e-126 421.8 0.0 1.6 1 1 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.20 EWM28002.1 - 4.8e-09 35.5 0.0 1.2e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.1 EWM28002.1 - 0.13 12.6 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 ACT domain Ribosomal_L27 PF01016.14 EWM28003.1 - 4.3e-34 116.1 1.1 5.6e-34 115.7 0.8 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein BSP_II PF05432.6 EWM28004.1 - 0.00091 18.5 18.4 0.00091 18.5 12.8 2.4 2 0 0 2 2 2 1 Bone sialoprotein II (BSP-II) Ribosomal_60s PF00428.14 EWM28004.1 - 0.004 17.5 8.4 0.004 17.5 5.8 3.4 3 1 0 3 3 3 1 60s Acidic ribosomal protein FAM176 PF14851.1 EWM28004.1 - 0.046 13.3 0.7 0.17 11.5 0.5 2.0 1 0 0 1 1 1 0 FAM176 family Nucleoplasmin PF03066.10 EWM28004.1 - 0.23 10.9 10.8 0.69 9.4 7.5 1.8 1 0 0 1 1 1 0 Nucleoplasmin YqhR PF11085.3 EWM28004.1 - 0.52 9.8 0.0 0.98 8.9 0.0 1.3 1 0 0 1 1 1 0 Conserved membrane protein YqhR Sigma70_ner PF04546.8 EWM28004.1 - 1.8 8.1 13.1 1.9 8.0 5.7 2.7 2 0 0 2 2 2 0 Sigma-70, non-essential region DNA_pol_phi PF04931.8 EWM28004.1 - 2.3 5.8 13.9 3.6 5.2 9.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi VID27 PF08553.5 EWM28004.1 - 4.1 5.4 7.6 6.5 4.8 5.2 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein CDC45 PF02724.9 EWM28004.1 - 5.6 4.8 9.8 10 3.9 6.8 1.3 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 EWM28004.1 - 9.4 5.3 7.6 22 4.2 5.3 1.5 1 0 0 1 1 1 0 NOA36 protein Prenylcys_lyase PF07156.9 EWM28006.1 - 1.6e-54 185.2 0.0 1.9e-54 184.9 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 EWM28006.1 - 5.9e-11 42.2 0.1 1.1e-10 41.3 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EWM28006.1 - 5.6e-06 25.4 1.2 0.00015 20.8 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EWM28006.1 - 6.8e-05 22.1 0.1 0.038 13.0 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 EWM28006.1 - 0.0022 17.8 0.6 0.014 15.2 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EWM28006.1 - 0.0032 17.5 0.3 0.0067 16.5 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EWM28006.1 - 0.038 13.0 0.1 0.081 12.0 0.1 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 EWM28006.1 - 0.082 12.6 0.5 0.35 10.6 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pkinase PF00069.20 EWM28007.1 - 2.6e-63 213.5 0.0 3.5e-63 213.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM28007.1 - 4.9e-29 101.1 0.0 7.8e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SR-25 PF10500.4 EWM28007.1 - 0.00077 19.0 4.9 0.00077 19.0 3.4 3.5 5 0 0 5 5 5 1 Nuclear RNA-splicing-associated protein APH PF01636.18 EWM28007.1 - 0.0021 17.8 0.2 0.017 14.8 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EWM28007.1 - 0.014 14.7 0.3 0.17 11.1 0.0 2.1 1 1 1 2 2 2 0 RIO1 family Kdo PF06293.9 EWM28007.1 - 0.023 13.7 0.4 0.039 13.0 0.3 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cytochrome_CBB3 PF13442.1 EWM28008.1 - 3.4e-09 36.7 0.0 1.4e-08 34.7 0.0 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 EWM28008.1 - 3e-08 34.3 0.0 5.3e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c Cytochrom_C550 PF14495.1 EWM28008.1 - 8.1e-06 25.3 0.3 3.6e-05 23.2 0.2 1.9 1 1 0 1 1 1 1 Cytochrome c-550 domain Haem_bd PF14376.1 EWM28008.1 - 0.046 13.3 0.1 0.39 10.3 0.0 2.2 1 1 1 2 2 2 0 Haem-binding domain 60KD_IMP PF02096.15 EWM28009.1 - 4e-62 209.4 4.5 5.7e-62 208.9 3.1 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein DUF2721 PF11026.3 EWM28010.1 - 0.32 10.6 8.6 1.2 8.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Hamartin PF04388.7 EWM28010.1 - 2.1 6.9 3.8 2.8 6.5 2.6 1.0 1 0 0 1 1 1 0 Hamartin protein CPSase_L_D2 PF02786.12 EWM28011.1 - 2.3e-112 373.4 0.3 4.3e-83 277.7 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 EWM28011.1 - 2.9e-49 165.8 0.0 7.5e-49 164.5 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EWM28011.1 - 2.5e-38 131.4 0.0 3.9e-37 127.5 0.0 2.9 3 0 0 3 3 3 1 Glutamine amidotransferase class-I CPSase_L_chain PF00289.17 EWM28011.1 - 2e-34 117.9 0.0 3.8e-18 65.5 0.0 2.8 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 EWM28011.1 - 4.1e-33 113.7 0.0 1.1e-32 112.3 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 EWM28011.1 - 5.1e-32 111.1 0.1 7.3e-18 64.9 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp PF02222.17 EWM28011.1 - 3.3e-18 65.6 0.1 1.8e-08 33.9 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 EWM28011.1 - 4.7e-17 61.7 0.1 2.5e-09 36.3 0.1 4.0 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 EWM28011.1 - 5.7e-17 61.4 0.0 2.9e-16 59.1 0.0 2.3 2 0 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.8 EWM28011.1 - 8.4e-14 51.4 0.2 1.2e-06 28.0 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 EWM28011.1 - 9.5e-05 21.9 0.0 0.0081 15.6 0.0 2.4 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EWM28011.1 - 0.00083 19.2 0.0 0.59 9.9 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 EWM28011.1 - 0.0026 17.2 2.0 0.12 11.7 0.1 3.1 2 1 0 2 2 2 1 Peptidase C26 ATP-grasp_5 PF13549.1 EWM28011.1 - 0.04 13.1 0.0 9.3 5.3 0.0 2.7 2 0 0 2 2 2 0 ATP-grasp domain KxDL PF10241.4 EWM28011.1 - 0.27 11.1 0.0 0.69 9.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein Mg-por_mtran_C PF07109.6 EWM28013.1 - 1.2e-35 121.3 0.3 9.9e-35 118.4 0.0 2.1 2 0 0 2 2 2 1 Magnesium-protoporphyrin IX methyltransferase C-terminus Methyltransf_23 PF13489.1 EWM28013.1 - 3.8e-13 49.4 0.0 7.2e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM28013.1 - 2e-10 41.2 0.1 4e-10 40.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM28013.1 - 2.2e-09 37.7 0.0 5.2e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM28013.1 - 3.4e-08 33.2 0.0 5.1e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM28013.1 - 3e-06 27.5 0.1 1.1e-05 25.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM28013.1 - 3.9e-06 27.2 0.1 1.1e-05 25.7 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain CMAS PF02353.15 EWM28013.1 - 1e-05 24.8 0.0 2.9e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 EWM28013.1 - 0.00026 20.2 0.2 0.00046 19.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EWM28013.1 - 0.00042 19.7 0.2 0.0014 18.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EWM28013.1 - 0.00049 19.2 0.4 0.0037 16.3 0.2 2.3 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family FmrO PF07091.6 EWM28013.1 - 0.001 18.1 0.0 0.0018 17.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_32 PF13679.1 EWM28013.1 - 0.0036 16.9 0.0 0.0069 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EWM28013.1 - 0.013 15.0 0.3 0.031 13.8 0.2 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EWM28013.1 - 0.023 14.7 0.0 0.091 12.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_30 PF05430.6 EWM28013.1 - 0.11 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase PepSY_2 PF13670.1 EWM28013.1 - 0.74 9.7 0.0 0.74 9.7 0.0 3.4 3 1 0 3 3 3 0 Peptidase propeptide and YPEB domain PWI PF01480.12 EWM28014.1 - 0.0063 16.5 0.0 0.0091 16.0 0.0 1.2 1 0 0 1 1 1 1 PWI domain eIF-5_eIF-2B PF01873.12 EWM28016.1 - 2.1e-33 114.6 0.0 3.6e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 EWM28016.1 - 1.6e-16 59.9 0.7 1.6e-16 59.9 0.5 3.4 3 1 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Zn_Tnp_IS1595 PF12760.2 EWM28016.1 - 0.011 15.5 0.9 0.021 14.6 0.3 1.8 1 1 0 1 1 1 0 Transposase zinc-ribbon domain DUF1682 PF07946.9 EWM28016.1 - 0.023 13.5 14.5 0.036 12.9 10.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Herpes_DNAp_acc PF04929.7 EWM28016.1 - 0.028 13.3 4.6 0.011 14.7 1.6 1.4 2 0 0 2 2 2 0 Herpes DNA replication accessory factor SAPS PF04499.10 EWM28016.1 - 0.54 8.8 5.6 0.71 8.4 3.9 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TFIIF_alpha PF05793.7 EWM28016.1 - 0.78 8.0 44.4 1.5 7.1 30.8 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) U79_P34 PF03064.11 EWM28016.1 - 1.6 8.2 32.4 2.7 7.4 22.5 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Med19 PF10278.4 EWM28016.1 - 2.6 7.6 37.3 1.4 8.5 24.5 1.5 1 1 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 CDC27 PF09507.5 EWM28016.1 - 4.5 6.3 35.5 7.7 5.6 24.6 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Epimerase PF01370.16 EWM28017.1 - 8.3e-57 192.3 0.0 1.1e-56 191.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EWM28017.1 - 6.6e-22 77.7 0.0 1.4e-14 53.7 0.0 2.0 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EWM28017.1 - 5.6e-20 71.3 0.0 9.5e-19 67.2 0.0 2.4 1 1 1 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 EWM28017.1 - 8.7e-20 70.5 0.0 1.4e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EWM28017.1 - 1.5e-16 60.1 0.0 2e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EWM28017.1 - 0.00072 19.6 0.0 0.0054 16.7 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding DUF2431 PF10354.4 EWM28020.1 - 4.8e-23 81.9 0.0 3.1e-22 79.3 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF2431) Methyltransf_26 PF13659.1 EWM28020.1 - 0.013 15.5 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain HalX PF08663.5 EWM28020.1 - 0.46 10.5 2.5 21 5.1 0.5 2.6 2 1 0 2 2 2 0 HalX domain Peptidase_S10 PF00450.17 EWM28021.1 - 5.3e-97 325.6 0.0 6.6e-97 325.2 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase fn3 PF00041.16 EWM28021.1 - 0.025 14.7 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 Fibronectin type III domain Polysacc_synt_C PF14667.1 EWM28022.1 - 0.0014 18.4 0.6 0.0018 18.0 0.4 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis C-terminal domain DUF4403 PF14356.1 EWM28022.1 - 0.0022 16.3 0.4 0.0028 16.0 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4403) NMN_transporter PF04973.7 EWM28022.1 - 0.0076 15.7 0.1 0.011 15.2 0.1 1.1 1 0 0 1 1 1 1 Nicotinamide mononucleotide transporter DUF4127 PF13552.1 EWM28022.1 - 0.095 11.0 0.6 0.16 10.3 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4127) ATPase_gene1 PF09527.5 EWM28022.1 - 0.12 12.1 2.8 0.18 11.5 1.9 1.2 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit (ATPase_gene1) zf-RING_2 PF13639.1 EWM28023.1 - 9.3e-07 28.5 14.9 9.3e-07 28.5 10.3 2.6 2 1 1 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EWM28023.1 - 6.5e-05 22.8 12.8 6.5e-05 22.8 8.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EWM28023.1 - 7.5e-05 22.3 7.3 0.00019 21.0 5.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EWM28023.1 - 0.00013 21.5 13.7 0.0004 19.9 9.5 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EWM28023.1 - 0.00083 19.1 9.4 0.00083 19.1 6.5 2.4 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EWM28023.1 - 0.0038 16.9 17.3 0.006 16.2 9.7 2.4 1 1 1 2 2 2 1 zinc-RING finger domain zf-Nse PF11789.3 EWM28023.1 - 0.0068 15.8 5.1 0.021 14.3 3.6 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Daxx PF03344.10 EWM28023.1 - 0.026 13.0 46.5 0.041 12.3 32.2 1.1 1 0 0 1 1 1 0 Daxx Family zf-rbx1 PF12678.2 EWM28023.1 - 1.2 9.2 18.0 3.6 7.7 0.7 2.6 2 0 0 2 2 2 0 RING-H2 zinc finger zf-TRAF PF02176.13 EWM28023.1 - 1.5 9.2 14.4 0.032 14.6 2.9 2.8 2 1 1 3 3 2 0 TRAF-type zinc finger DDHD PF02862.12 EWM28023.1 - 5 6.8 7.2 9 6.0 5.0 1.4 1 0 0 1 1 1 0 DDHD domain zf-C3HC4_3 PF13920.1 EWM28023.1 - 5 6.8 22.0 0.011 15.3 7.0 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) AAA_2 PF07724.9 EWM28024.1 - 1.9e-40 138.5 0.0 3.3e-40 137.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EWM28024.1 - 4.1e-13 49.6 0.0 8.3e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EWM28024.1 - 5.6e-12 45.3 0.1 1.1e-11 44.5 0.1 1.4 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_22 PF13401.1 EWM28024.1 - 2.4e-05 24.4 0.2 0.00017 21.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain MCM PF00493.18 EWM28024.1 - 3.6e-05 22.7 0.0 5.7e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family AAA_5 PF07728.9 EWM28024.1 - 6.4e-05 22.7 0.1 0.0002 21.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EWM28024.1 - 8e-05 23.4 0.0 0.00017 22.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EWM28024.1 - 0.00015 22.0 0.0 0.00032 21.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EWM28024.1 - 0.00025 20.2 0.0 0.0044 16.1 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EWM28024.1 - 0.00026 20.5 0.1 0.0059 16.1 0.0 2.5 2 1 0 2 2 1 1 Sigma-54 interaction domain AAA_16 PF13191.1 EWM28024.1 - 0.00072 19.5 0.0 0.0023 17.9 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EWM28024.1 - 0.00073 18.6 0.1 0.0024 16.9 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activ_2 PF14532.1 EWM28024.1 - 0.00077 19.5 0.0 0.0039 17.2 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain T2SE PF00437.15 EWM28024.1 - 0.0024 16.8 0.0 0.004 16.0 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.22 EWM28024.1 - 0.0024 18.1 0.0 0.0052 17.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter IstB_IS21 PF01695.12 EWM28024.1 - 0.0029 17.0 0.0 0.0053 16.1 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 EWM28024.1 - 0.0033 17.3 0.0 0.0056 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain zf-FPG_IleRS PF06827.9 EWM28024.1 - 0.0066 16.0 0.1 0.017 14.7 0.1 1.8 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS ResIII PF04851.10 EWM28024.1 - 0.024 14.4 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EWM28024.1 - 0.025 14.3 0.0 0.077 12.7 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 EWM28024.1 - 0.027 14.3 0.0 0.069 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EWM28024.1 - 0.033 13.8 0.1 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.11 EWM28024.1 - 0.045 12.9 0.0 0.11 11.7 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein G-alpha PF00503.15 EWM28024.1 - 0.053 12.1 0.0 0.091 11.4 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_29 PF13555.1 EWM28024.1 - 0.056 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.1 EWM28024.1 - 0.078 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EWM28024.1 - 0.11 11.8 0.2 0.42 9.9 0.1 1.9 3 0 0 3 3 2 0 AAA-like domain AAA_25 PF13481.1 EWM28024.1 - 0.14 11.5 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EWM28024.1 - 0.16 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.4 EWM28024.1 - 0.19 10.3 0.0 0.3 9.6 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Abhydrolase_5 PF12695.2 EWM28025.1 - 0.00014 21.6 0.1 0.00026 20.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EWM28025.1 - 0.00046 20.1 0.5 0.00089 19.1 0.3 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EWM28025.1 - 0.058 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.15 EWM28025.1 - 0.088 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain 7TM_GPCR_Srx PF10328.4 EWM28025.1 - 0.13 11.3 0.2 0.19 10.7 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF726 PF05277.7 EWM28025.1 - 0.13 11.0 0.1 0.21 10.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) TMEM223 PF14640.1 EWM28026.1 - 2.9e-11 43.6 0.3 6.3e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 Transmembrane protein 223 ATP-synt PF00231.14 EWM28027.1 - 1.6e-73 247.6 0.1 2e-73 247.2 0.1 1.1 1 0 0 1 1 1 1 ATP synthase SET PF00856.23 EWM28028.1 - 0.088 13.1 0.0 1.2 9.3 0.0 2.4 3 0 0 3 3 3 0 SET domain Tfb2 PF03849.9 EWM28029.1 - 1.8e-49 168.3 0.0 5.3e-48 163.5 0.0 2.0 1 1 0 1 1 1 1 Transcription factor Tfb2 Rieske PF00355.21 EWM28030.1 - 1e-14 53.8 0.0 2.2e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PAP_fibrillin PF04755.7 EWM28030.1 - 2.8e-13 50.0 0.0 1e-08 35.1 0.0 2.9 2 1 0 2 2 2 2 PAP_fibrillin Rieske_2 PF13806.1 EWM28030.1 - 5e-06 26.1 0.0 1.1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Ring_hydroxyl_A PF00848.14 EWM28030.1 - 0.16 11.5 3.0 0.63 9.6 0.2 2.9 2 1 0 2 2 2 0 Ring hydroxylating alpha subunit (catalytic domain) DUF1053 PF06327.9 EWM28031.1 - 0.11 12.8 0.3 0.26 11.6 0.2 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) FYVE PF01363.16 EWM28032.1 - 1.4e-15 56.9 3.4 2.4e-15 56.1 2.4 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 EWM28032.1 - 0.0061 16.4 0.7 0.011 15.6 0.5 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger YuzL PF14115.1 EWM28032.1 - 0.41 10.9 2.2 0.79 10.0 1.5 1.4 1 0 0 1 1 1 0 YuzL-like protein DUF2688 PF10892.3 EWM28032.1 - 1.4 8.6 4.0 1.1 8.9 0.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2688) Epimerase PF01370.16 EWM28034.1 - 8.4e-24 84.2 0.0 1.3e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EWM28034.1 - 6.2e-23 80.8 0.0 8.1e-23 80.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EWM28034.1 - 4.2e-15 56.2 0.0 8.6e-15 55.2 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EWM28034.1 - 6.9e-14 51.3 0.0 1.7e-13 50.0 0.0 1.7 1 1 1 2 2 2 1 Male sterility protein NmrA PF05368.8 EWM28034.1 - 2.3e-12 46.6 0.0 7.9e-10 38.3 0.0 2.3 2 0 0 2 2 2 2 NmrA-like family adh_short PF00106.20 EWM28034.1 - 7.4e-08 32.4 0.2 1.7e-07 31.2 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EWM28034.1 - 1.4e-05 24.8 0.0 2.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EWM28034.1 - 0.0094 14.8 0.0 0.021 13.7 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein DUF2215 PF10225.4 EWM28036.1 - 3.9e-06 26.4 1.7 0.0078 15.6 2.1 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2215) Arv1 PF04161.8 EWM28037.1 - 3.6e-32 111.9 0.4 4.6e-32 111.6 0.3 1.1 1 0 0 1 1 1 1 Arv1-like family DUF3318 PF11780.3 EWM28037.1 - 0.04 13.4 0.1 0.087 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) DZR PF12773.2 EWM28038.1 - 5.1 6.9 7.8 2 8.3 0.6 2.3 2 0 0 2 2 2 0 Double zinc ribbon CN_hydrolase PF00795.17 EWM28040.1 - 2.4e-29 101.9 0.0 4.8e-29 101.0 0.0 1.5 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase CBFD_NFYB_HMF PF00808.18 EWM28041.1 - 2.9e-28 97.7 0.2 4e-28 97.2 0.2 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EWM28041.1 - 3.1e-05 24.0 0.0 4.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Tmemb_cc2 PF10267.4 EWM28041.1 - 0.055 12.0 0.8 0.069 11.7 0.6 1.0 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Bromo_TP PF07524.8 EWM28041.1 - 0.07 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID-18kDa PF02269.11 EWM28041.1 - 0.093 12.5 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Fe-ADH PF00465.14 EWM28042.1 - 3.3e-36 124.7 0.1 4.1e-36 124.3 0.1 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EWM28042.1 - 8.9e-06 25.1 0.0 5.3e-05 22.6 0.0 1.9 1 1 1 2 2 2 1 Iron-containing alcohol dehydrogenase adh_short PF00106.20 EWM28043.1 - 8.3e-14 51.8 0.0 4.2e-13 49.5 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EWM28043.1 - 0.00021 21.0 0.0 0.00033 20.3 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EWM28043.1 - 0.035 13.8 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase HAD PF12710.2 EWM28043.1 - 0.065 13.3 0.1 0.21 11.7 0.1 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Eno-Rase_NADH_b PF12242.3 EWM28043.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RRM_1 PF00076.17 EWM28044.1 - 3e-05 23.5 0.0 5.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM28044.1 - 0.00052 19.9 0.0 0.00088 19.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM28044.1 - 0.0028 17.4 0.0 0.0041 16.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4407 PF14362.1 EWM28044.1 - 0.1 11.5 2.1 0.15 11.0 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GRP PF07172.6 EWM28044.1 - 0.34 11.4 15.4 1.8 9.0 5.0 2.6 3 0 0 3 3 3 0 Glycine rich protein family PRP38 PF03371.10 EWM28045.1 - 1.5e-47 161.3 0.0 2e-47 161.0 0.0 1.1 1 0 0 1 1 1 1 PRP38 family YjeF_N PF03853.10 EWM28046.1 - 2.6e-40 137.7 0.0 3.6e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus CutA1 PF03091.10 EWM28046.1 - 1.7e-31 107.8 0.0 2.7e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein TBP PF00352.16 EWM28047.1 - 6.5e-61 201.6 0.0 5.2e-31 105.8 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) XPG_N PF00752.12 EWM28048.1 - 3.1e-29 101.1 0.0 7.5e-29 99.9 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EWM28048.1 - 1.4e-24 85.9 0.0 2.7e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 EWM28048.1 - 0.014 14.9 0.0 0.035 13.5 0.0 1.6 1 0 0 1 1 1 0 XPG domain containing Herpes_UL37_2 PF07413.6 EWM28048.1 - 0.028 13.2 0.0 0.052 12.3 0.0 1.3 1 0 0 1 1 1 0 Betaherpesvirus immediate-early glycoprotein UL37 DUF4414 PF14377.1 EWM28048.1 - 0.087 12.7 0.2 0.087 12.7 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4414) Ribosomal_60s PF00428.14 EWM28048.1 - 2.3 8.6 11.5 1.1 9.6 5.8 2.2 1 1 0 1 1 1 0 60s Acidic ribosomal protein Nol1_Nop2_Fmu PF01189.12 EWM28049.1 - 8.4e-16 58.1 0.0 1.3e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family NusB PF01029.13 EWM28049.1 - 9.9e-14 51.4 0.0 1.8e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 NusB family Methyltransf_26 PF13659.1 EWM28049.1 - 0.0039 17.1 0.0 0.0099 15.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Zn_clus PF00172.13 EWM28051.1 - 2.3e-07 30.6 12.0 4.8e-07 29.5 8.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ER PF01133.12 EWM28052.1 - 3.5e-38 129.4 0.0 3.9e-38 129.3 0.0 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary Thioredoxin PF00085.15 EWM28053.1 - 3e-24 84.7 0.0 4.7e-24 84.0 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EWM28053.1 - 2.9e-06 27.3 0.0 4.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EWM28053.1 - 3.5e-06 27.1 0.1 2.1e-05 24.6 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 EWM28053.1 - 0.00052 19.5 0.0 0.00067 19.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 EWM28053.1 - 0.00061 19.3 0.2 0.0014 18.1 0.1 1.6 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.16 EWM28053.1 - 0.0008 19.0 0.1 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.1 EWM28053.1 - 0.00089 19.2 0.1 0.002 18.1 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.19 EWM28053.1 - 0.0011 18.9 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin DUF953 PF06110.6 EWM28053.1 - 0.0043 16.4 0.1 0.0067 15.8 0.1 1.4 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Phosducin PF02114.11 EWM28053.1 - 0.0064 15.2 0.0 0.0078 14.9 0.0 1.2 1 0 0 1 1 1 1 Phosducin DUF4083 PF13314.1 EWM28055.1 - 0.076 12.8 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) PseudoU_synth_1 PF01416.15 EWM28056.1 - 1e-24 86.9 0.0 4.7e-12 46.2 0.0 2.6 2 1 0 2 2 2 2 tRNA pseudouridine synthase LTD PF00932.14 EWM28057.1 - 4.6e-07 29.9 0.0 8.3e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Lamin Tail Domain GAS PF13851.1 EWM28057.1 - 4.9e-07 29.1 64.6 0.004 16.3 4.6 4.3 2 2 2 4 4 4 3 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 EWM28057.1 - 0.0013 18.6 14.0 0.0013 18.6 9.7 6.6 2 1 3 5 5 5 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phage_GP20 PF06810.6 EWM28057.1 - 0.0015 18.0 46.9 0.057 12.8 1.8 5.3 3 1 2 6 6 6 3 Phage minor structural protein GP20 NPV_P10 PF05531.7 EWM28057.1 - 0.029 14.6 19.4 0.15 12.2 0.6 5.7 5 1 0 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.6 EWM28057.1 - 0.057 13.2 14.1 15 5.4 0.0 5.5 4 2 1 5 5 5 0 Bacterial protein of unknown function (DUF948) AAA_13 PF13166.1 EWM28057.1 - 0.067 11.6 43.1 0.057 11.8 14.5 3.1 1 1 2 3 3 3 0 AAA domain IncA PF04156.9 EWM28057.1 - 0.26 10.8 79.4 0.26 10.8 8.2 4.9 2 1 1 3 3 3 0 IncA protein DASH_Dam1 PF08653.5 EWM28057.1 - 0.29 10.9 15.3 0.29 10.9 0.1 5.6 5 1 1 6 6 6 0 DASH complex subunit Dam1 Fib_alpha PF08702.5 EWM28057.1 - 0.48 10.5 37.4 0.12 12.5 2.6 5.1 2 1 4 6 6 6 0 Fibrinogen alpha/beta chain family BLOC1_2 PF10046.4 EWM28057.1 - 0.49 10.5 37.8 0.35 11.0 2.6 6.4 4 2 3 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.6 EWM28057.1 - 0.77 9.6 34.4 0.35 10.8 0.5 8.1 5 3 0 6 6 6 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.7 EWM28057.1 - 0.77 9.5 18.7 6.8 6.5 0.2 4.6 3 2 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 EWM28057.1 - 1.2 8.2 12.5 1.6 7.8 0.5 3.2 3 1 1 4 4 4 0 Reovirus sigma C capsid protein Filament PF00038.16 EWM28057.1 - 1.4 8.2 70.5 0.34 10.3 33.4 3.5 1 1 2 3 3 3 0 Intermediate filament protein DUF972 PF06156.8 EWM28057.1 - 2 8.7 61.4 0.49 10.7 1.5 7.6 2 1 4 6 6 6 0 Protein of unknown function (DUF972) bZIP_1 PF00170.16 EWM28057.1 - 3.4 7.6 74.3 0.61 10.0 2.8 10.7 6 3 4 10 10 10 0 bZIP transcription factor DUF3505 PF12013.3 EWM28057.1 - 5.5 7.2 13.8 7.9 6.7 0.5 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3505) TBPIP PF07106.8 EWM28057.1 - 7.7 6.0 55.4 0.7 9.4 6.3 5.7 1 1 3 5 5 5 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HALZ PF02183.13 EWM28057.1 - 7.8 6.3 51.2 1.5 8.5 0.5 9.0 7 2 1 8 8 8 0 Homeobox associated leucine zipper DUF3584 PF12128.3 EWM28057.1 - 8.8 3.5 63.0 1.7 5.8 29.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) MFS_1 PF07690.11 EWM28058.1 - 5.2e-28 97.7 35.5 2.3e-26 92.3 9.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CRM1_C PF08767.6 EWM28059.1 - 1.7e-109 365.5 1.5 3e-109 364.8 0.1 2.2 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 EWM28059.1 - 2.7e-37 127.9 5.6 1.2e-36 125.8 3.8 2.2 1 0 0 1 1 1 1 Exportin 1-like protein IBN_N PF03810.14 EWM28059.1 - 6.5e-10 38.7 0.0 2.6e-09 36.8 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3638 PF12340.3 EWM28060.1 - 5.1e-26 91.0 0.3 4.5e-23 81.4 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EWM28060.1 - 6.5e-17 60.3 0.1 1.6e-16 59.0 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Thioredoxin_8 PF13905.1 EWM28060.1 - 8.2e-12 45.0 0.0 2.1e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like EF-hand_7 PF13499.1 EWM28060.1 - 2.9e-07 30.5 0.1 1.4e-06 28.2 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair UBA PF00627.26 EWM28060.1 - 3.3e-07 29.9 1.0 3e-05 23.7 0.2 3.5 2 0 0 2 2 2 1 UBA/TS-N domain EF-hand_1 PF00036.27 EWM28060.1 - 1.5e-05 23.9 0.0 0.015 14.5 0.0 2.8 2 0 0 2 2 2 2 EF hand zf-RanBP PF00641.13 EWM28060.1 - 2.6e-05 23.2 2.4 2.6e-05 23.2 1.6 3.8 4 0 0 4 4 4 2 Zn-finger in Ran binding protein and others EF-hand_6 PF13405.1 EWM28060.1 - 0.00069 19.3 0.1 0.011 15.5 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 EWM28060.1 - 0.0056 16.2 0.1 1.8 8.2 0.0 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EWM28060.1 - 0.046 13.0 0.0 0.21 10.9 0.0 2.2 1 0 0 1 1 1 0 EF hand PA26 PF04636.8 EWM28060.1 - 6.2 5.3 3.8 9.9 4.7 2.7 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Ycf1 PF05758.7 EWM28060.1 - 10 3.7 1.8 15 3.1 1.2 1.1 1 0 0 1 1 1 0 Ycf1 Gryzun PF07919.7 EWM28061.1 - 8.8e-13 47.4 0.0 8.8e-11 40.8 0.0 2.1 2 0 0 2 2 2 2 Gryzun, putative trafficking through Golgi Glyco_transf_92 PF01697.22 EWM28062.1 - 1.2e-13 51.0 0.3 1.6e-13 50.6 0.2 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.1 EWM28062.1 - 1.9e-08 34.4 0.0 4.9e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glycos_transf_2 PF00535.21 EWM28062.1 - 0.013 15.2 0.0 0.032 13.9 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_transf_92 PF01697.22 EWM28063.1 - 1.2e-13 51.0 0.3 1.6e-13 50.6 0.2 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.1 EWM28063.1 - 1.9e-08 34.4 0.0 4.9e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glycos_transf_2 PF00535.21 EWM28063.1 - 0.013 15.2 0.0 0.032 13.9 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 IQ PF00612.22 EWM28065.1 - 5e-19 66.0 203.2 0.001 18.5 0.7 26.0 24 2 2 26 26 26 20 IQ calmodulin-binding motif CH PF00307.26 EWM28065.1 - 0.0084 16.1 0.1 0.18 11.8 0.0 3.0 2 1 1 3 3 3 1 Calponin homology (CH) domain Ribosomal_S8 PF00410.14 EWM28066.1 - 1.6e-23 82.9 0.0 1.9e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 gp45-slide_C PF09116.5 EWM28066.1 - 0.13 12.2 0.1 3.2 7.7 0.0 2.5 1 1 2 3 3 3 0 gp45 sliding clamp, C terminal adh_short PF00106.20 EWM28067.1 - 8.6e-24 84.3 0.0 1.3e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EWM28067.1 - 1.6e-07 31.1 0.0 4e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EWM28067.1 - 9.3e-05 22.3 0.0 0.00013 21.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EWM28067.1 - 0.0018 18.3 0.0 0.0041 17.1 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Glyco_transf_5 PF08323.6 EWM28067.1 - 0.029 13.8 0.0 0.19 11.1 0.0 1.9 2 0 0 2 2 2 0 Starch synthase catalytic domain Epimerase PF01370.16 EWM28067.1 - 0.052 12.9 0.0 0.21 10.9 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 EWM28067.1 - 0.072 12.2 0.0 0.4 9.8 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain COesterase PF00135.23 EWM28068.1 - 1.1e-111 374.1 0.0 1.5e-111 373.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EWM28068.1 - 0.0002 21.0 0.3 0.0011 18.6 0.3 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EWM28068.1 - 0.011 14.9 0.5 0.02 14.0 0.3 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EWM28068.1 - 0.11 12.2 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Rad4 PF03835.10 EWM28069.1 - 2e-11 43.5 0.0 3.7e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain PUB PF09409.5 EWM28069.1 - 4.3e-09 36.0 0.0 9.4e-09 34.9 0.0 1.5 1 0 0 1 1 1 1 PUB domain Transglut_core PF01841.14 EWM28069.1 - 6.5e-09 36.0 0.2 1.4e-08 34.9 0.1 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Jacalin PF01419.12 EWM28069.1 - 0.056 13.3 0.0 0.097 12.5 0.0 1.3 1 0 0 1 1 1 0 Jacalin-like lectin domain CHORD PF04968.7 EWM28070.1 - 0.013 15.7 0.2 0.013 15.7 0.2 2.6 2 1 0 2 2 2 0 CHORD BTK PF00779.14 EWM28070.1 - 0.02 14.4 2.7 0.8 9.3 0.6 2.6 2 0 0 2 2 2 0 BTK motif MNNL PF07657.8 EWM28070.1 - 0.024 14.5 3.0 0.05 13.5 0.2 2.3 1 1 1 2 2 2 0 N terminus of Notch ligand HupE_UreJ PF04955.7 EWM28073.1 - 6.1 6.1 16.1 50 3.1 11.2 2.6 1 1 0 1 1 1 0 HupE / UreJ protein ubiquitin PF00240.18 EWM28075.1 - 1.1e-27 95.1 0.1 1.5e-27 94.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EWM28075.1 - 2.7e-16 59.0 0.2 3.4e-16 58.6 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EWM28075.1 - 0.0012 19.0 0.1 0.0053 16.9 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain CTDII PF01556.13 EWM28075.1 - 0.0081 16.0 0.3 0.012 15.5 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain TUG-UBL1 PF11470.3 EWM28075.1 - 0.03 14.2 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 GLUT4 regulating protein TUG Thioredoxin PF00085.15 EWM28076.1 - 3.3e-20 71.7 0.0 6.6e-20 70.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin PUB PF09409.5 EWM28076.1 - 9.6e-15 54.1 0.0 2e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 PUB domain UBA PF00627.26 EWM28076.1 - 3.1e-05 23.6 0.0 0.00032 20.4 0.0 2.7 3 0 0 3 3 3 1 UBA/TS-N domain Thioredoxin_8 PF13905.1 EWM28076.1 - 0.0022 18.0 0.0 0.0044 17.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.1 EWM28076.1 - 0.0047 16.9 0.0 0.017 15.1 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EWM28076.1 - 0.011 15.2 1.5 0.015 14.8 0.0 1.9 2 1 0 2 2 2 0 Thioredoxin AhpC-TSA PF00578.16 EWM28076.1 - 0.013 15.1 0.0 0.085 12.5 0.0 2.2 2 0 0 2 2 2 0 AhpC/TSA family Thioredoxin_2 PF13098.1 EWM28076.1 - 0.021 14.9 0.0 0.096 12.8 0.0 2.2 2 1 0 2 2 2 0 Thioredoxin-like domain Redoxin PF08534.5 EWM28076.1 - 0.12 11.8 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 Redoxin zf-RING_2 PF13639.1 EWM28077.1 - 3.1e-09 36.5 10.0 7.9e-09 35.2 6.9 1.7 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 EWM28077.1 - 0.00082 19.2 3.8 0.0018 18.2 2.6 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_3 PF13920.1 EWM28077.1 - 0.0023 17.5 5.4 0.0058 16.2 3.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EWM28077.1 - 0.014 15.4 7.7 0.03 14.3 5.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EWM28077.1 - 0.065 13.3 6.9 0.23 11.6 4.8 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger Fibroin_P25 PF07294.6 EWM28078.1 - 0.054 12.9 0.1 0.073 12.5 0.0 1.2 1 0 0 1 1 1 0 Fibroin P25 DUF3805 PF12712.2 EWM28078.1 - 0.15 11.8 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3805) AMP-binding PF00501.23 EWM28080.1 - 4e-78 262.6 0.0 5.9e-78 262.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EWM28080.1 - 6.6e-06 26.9 0.1 1.5e-05 25.8 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 EWM28081.1 - 3.7e-78 262.7 0.0 5.5e-78 262.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EWM28081.1 - 6.3e-06 27.0 0.1 1.4e-05 25.9 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SET PF00856.23 EWM28082.1 - 0.0014 18.9 0.0 0.09 13.0 0.0 2.6 1 1 0 1 1 1 1 SET domain RNA_pol_Rpb8 PF03870.10 EWM28083.1 - 7.4e-35 120.1 0.1 9.4e-35 119.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb8 DndB PF14072.1 EWM28085.1 - 9.8e-05 21.6 0.0 0.0002 20.6 0.0 1.4 1 1 0 1 1 1 1 DNA-sulfur modification-associated DUF262 PF03235.9 EWM28085.1 - 0.0056 16.6 0.0 0.0074 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF262 SGS PF05002.10 EWM28086.1 - 3.2e-24 84.4 4.6 5.7e-24 83.6 3.2 1.4 1 0 0 1 1 1 1 SGS domain CS PF04969.11 EWM28086.1 - 8.2e-15 55.1 0.0 1.4e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 EWM28086.1 - 3.1e-10 39.5 1.7 1.2e-06 28.0 0.7 2.3 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EWM28086.1 - 9.3e-07 28.2 0.1 0.019 14.5 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EWM28086.1 - 1.4e-06 27.7 3.8 0.014 15.2 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EWM28086.1 - 5.4e-05 23.7 8.1 0.00044 20.8 2.4 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EWM28086.1 - 0.005 17.1 1.2 0.02 15.1 0.2 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EWM28086.1 - 0.0092 16.3 3.2 2.4 8.7 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EWM28086.1 - 0.024 15.2 7.5 0.99 10.2 0.2 3.5 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 EWM28086.1 - 0.04 13.7 2.6 0.089 12.6 0.9 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EWM28086.1 - 0.042 13.9 0.4 0.079 13.1 0.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EWM28086.1 - 0.065 13.1 2.0 0.36 10.7 0.3 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EWM28086.1 - 0.11 12.3 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EWM28086.1 - 0.13 12.5 0.2 1.4 9.2 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Pyrid_oxidase_2 PF13883.1 EWM28087.1 - 7.8e-26 90.8 0.0 1.3e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF2470 PF10615.4 EWM28087.1 - 5e-12 45.8 0.0 8.5e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Pyridox_oxidase PF01243.15 EWM28087.1 - 7.5e-06 25.8 0.0 1.6e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF1180 PF06679.7 EWM28087.1 - 1.2 9.0 5.1 2 8.2 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) PBP1_TM PF14812.1 EWM28088.1 - 0.02 15.1 0.0 0.032 14.5 0.0 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SLAC1 PF03595.12 EWM28088.1 - 0.039 12.6 12.2 0.052 12.2 8.4 1.0 1 0 0 1 1 1 0 Voltage-dependent anion channel DUF679 PF05078.7 EWM28088.1 - 0.047 13.3 1.1 0.047 13.3 0.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF679) 7tm_6 PF02949.15 EWM28088.1 - 0.2 10.4 5.4 0.08 11.7 1.4 1.9 1 1 1 2 2 2 0 7tm Odorant receptor SET PF00856.23 EWM28089.1 - 8.4e-11 42.4 0.0 1.7e-10 41.4 0.0 1.7 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 EWM28089.1 - 0.0013 18.5 9.6 0.0013 18.5 6.6 3.2 4 0 0 4 4 4 1 MYND finger EXS PF03124.9 EWM28090.1 - 4.3e-59 200.2 0.4 5.4e-59 199.9 0.3 1.0 1 0 0 1 1 1 1 EXS family LSM PF01423.17 EWM28091.1 - 5.8e-18 64.2 0.0 7.4e-18 63.8 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EWM28091.1 - 0.015 15.1 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain PPR_3 PF13812.1 EWM28093.1 - 2.6e-33 111.4 0.4 0.00012 22.0 0.0 8.5 8 0 0 8 8 8 5 Pentatricopeptide repeat domain PPR PF01535.15 EWM28093.1 - 1.4e-22 78.0 0.3 0.0026 17.6 0.0 7.1 8 0 0 8 8 8 5 PPR repeat PPR_2 PF13041.1 EWM28093.1 - 3.1e-21 75.0 0.0 1.5e-07 31.2 0.0 6.6 3 2 4 7 7 7 5 PPR repeat family PPR_1 PF12854.2 EWM28093.1 - 2.9e-10 39.4 0.0 0.037 13.5 0.0 5.6 7 0 0 7 7 7 2 PPR repeat TPR_7 PF13176.1 EWM28093.1 - 0.0091 15.7 0.2 20 5.2 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 EWM28093.1 - 0.03 14.7 5.9 3.1 8.4 0.7 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EWM28093.1 - 0.037 14.6 15.0 0.81 10.4 0.1 6.1 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.1 EWM28093.1 - 0.055 13.4 8.5 15 5.7 0.2 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EWM28093.1 - 0.59 10.7 2.5 32 5.2 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Na_H_Exchanger PF00999.16 EWM28094.1 - 1.1e-41 142.6 42.5 1.6e-41 142.1 29.5 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Prefoldin_2 PF01920.15 EWM28094.1 - 0.011 15.4 2.0 0.028 14.1 1.4 1.7 1 0 0 1 1 1 0 Prefoldin subunit Spc7 PF08317.6 EWM28094.1 - 0.42 9.2 5.5 0.88 8.1 3.8 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein VIT1 PF01988.14 EWM28095.1 - 1e-59 201.5 0.1 1.3e-59 201.2 0.1 1.1 1 0 0 1 1 1 1 VIT family DNA_pol_A PF00476.15 EWM28096.1 - 3.3e-63 213.5 0.9 3.6e-58 197.0 0.2 2.2 2 0 0 2 2 2 2 DNA polymerase family A DEAD PF00270.24 EWM28096.1 - 8.4e-16 57.9 0.0 2e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EWM28096.1 - 4.5e-12 45.6 0.1 1.1e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EWM28096.1 - 1.4e-05 24.9 0.0 2.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Tubulin PF00091.20 EWM28097.1 - 1.9e-38 132.4 1.3 5.2e-38 131.0 0.9 1.6 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.1 EWM28097.1 - 1.6 7.5 9.3 14 4.4 0.1 2.8 1 1 1 2 2 2 0 Tubulin like Sulfatase PF00884.18 EWM28099.1 - 9.4e-44 149.8 0.0 1.4e-43 149.3 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EWM28099.1 - 4.1e-05 23.0 0.0 0.0033 16.7 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EWM28099.1 - 0.00042 18.8 0.2 0.001 17.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.13 EWM28099.1 - 0.0091 15.4 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily HSP90 PF00183.13 EWM28100.1 - 3.8e-149 497.4 4.1 6.7e-141 470.2 1.0 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.1 EWM28100.1 - 2.9e-12 46.4 0.2 8.7e-12 44.8 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EWM28100.1 - 3e-10 39.7 0.0 8e-10 38.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Histidinol_dh PF00815.15 EWM28101.1 - 4.5e-109 364.8 2.2 5.5e-109 364.5 1.6 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase TetR_C_6 PF13977.1 EWM28101.1 - 0.025 14.6 1.0 0.072 13.1 0.7 1.8 1 0 0 1 1 1 0 Bacterial transcriptional repressor DUF1995 PF09353.5 EWM28102.1 - 4.7e-20 72.1 0.0 7.4e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) DUF2470 PF10615.4 EWM28102.1 - 0.019 15.1 0.0 0.035 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2470) PALP PF00291.20 EWM28104.1 - 2e-71 240.7 5.2 3.2e-71 240.0 3.6 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 EWM28104.1 - 1e-36 124.4 0.0 7.3e-21 73.5 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase ADH_zinc_N PF00107.21 EWM28104.1 - 0.0012 18.3 0.5 0.064 12.8 0.0 2.9 1 1 2 3 3 3 1 Zinc-binding dehydrogenase GTP_EFTU PF00009.22 EWM28105.1 - 1.3e-45 155.1 0.1 5.3e-45 153.1 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EWM28105.1 - 1.2e-13 50.7 0.0 3.1e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EWM28105.1 - 3.5e-08 33.4 0.3 1e-07 31.9 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Miro PF08477.8 EWM28105.1 - 0.0027 18.2 0.0 0.0092 16.4 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EWM28105.1 - 0.0095 15.8 0.0 0.03 14.2 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.13 EWM28105.1 - 0.034 13.1 0.0 0.061 12.3 0.0 1.3 1 0 0 1 1 1 0 Septin RRM_1 PF00076.17 EWM28106.1 - 1.8e-52 174.8 0.0 1.5e-19 69.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM28106.1 - 8e-37 125.0 0.0 6.5e-12 45.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM28106.1 - 2e-28 97.9 0.1 9.9e-10 38.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC2_membrane PF01061.19 EWM28107.1 - 2.4e-29 101.9 16.9 3.9e-29 101.3 11.7 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EWM28107.1 - 1.2e-17 64.5 0.0 1.7e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 EWM28107.1 - 9.8e-06 24.8 18.9 1.6e-05 24.1 13.1 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.1 EWM28107.1 - 4.7e-05 23.5 0.0 0.00088 19.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EWM28107.1 - 0.0015 17.7 0.0 0.0025 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EWM28107.1 - 0.056 13.4 0.0 0.14 12.0 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain Adeno_E1B_55K_N PF04623.7 EWM28107.1 - 0.057 13.9 0.7 50 4.4 0.0 3.4 3 0 0 3 3 3 0 Adenovirus E1B protein N-terminus ATP-synt_ab PF00006.20 EWM28107.1 - 0.077 12.4 0.1 0.12 11.8 0.1 1.5 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain SMC_N PF02463.14 EWM28107.1 - 0.092 11.9 0.0 12 4.9 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EWM28107.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sec1 PF00995.18 EWM28108.1 - 4.6e-117 392.0 0.0 5.2e-117 391.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family VQ PF05678.9 EWM28108.1 - 0.15 11.1 0.2 0.37 9.8 0.1 1.6 1 0 0 1 1 1 0 VQ motif PrmA PF06325.8 EWM28110.1 - 2.9e-42 144.8 0.0 4.8e-42 144.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EWM28110.1 - 2.2e-08 34.6 0.1 4.7e-08 33.5 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM28110.1 - 3.3e-08 33.5 0.2 1.4e-07 31.5 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EWM28110.1 - 1.5e-07 30.9 0.1 5.4e-07 29.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EWM28110.1 - 1.8e-06 27.5 0.0 6.5e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM28110.1 - 0.00031 20.4 0.1 0.00093 18.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM28110.1 - 0.0077 16.7 0.0 0.023 15.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EWM28110.1 - 0.032 13.7 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.11 EWM28110.1 - 0.037 13.5 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_25 PF13649.1 EWM28110.1 - 0.056 13.8 0.1 0.15 12.3 0.0 1.8 2 0 0 2 2 1 0 Methyltransferase domain Methyltrans_SAM PF10672.4 EWM28110.1 - 0.095 11.5 0.1 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase UPF0020 PF01170.13 EWM28110.1 - 0.15 11.6 0.2 0.37 10.3 0.0 1.7 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.1 EWM28110.1 - 0.15 11.7 0.1 0.33 10.6 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain CBM_25 PF03423.8 EWM28111.1 - 0.00012 22.0 0.0 0.00021 21.3 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate binding domain (family 25) YL1 PF05764.8 EWM28111.1 - 2 7.9 8.2 3 7.3 5.7 1.2 1 0 0 1 1 1 0 YL1 nuclear protein LLC1 PF14945.1 EWM28112.1 - 0.12 12.6 1.9 0.42 10.9 1.3 1.9 1 0 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein zf-RING_2 PF13639.1 EWM28114.1 - 2.4e-08 33.6 15.2 4.4e-08 32.8 10.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EWM28114.1 - 2.1e-07 30.4 14.9 3.6e-07 29.7 10.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EWM28114.1 - 1.1e-06 28.1 11.5 1.8e-06 27.4 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EWM28114.1 - 3.7e-06 26.9 6.4 6.6e-06 26.1 4.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EWM28114.1 - 5.2e-06 26.3 15.1 9.4e-06 25.5 10.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EWM28114.1 - 7e-05 22.4 13.7 7e-05 22.4 9.5 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EWM28114.1 - 0.0024 17.6 6.5 0.0045 16.7 4.5 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EWM28114.1 - 0.0065 16.3 14.8 0.012 15.5 10.2 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 EWM28114.1 - 0.012 15.1 9.0 0.022 14.2 6.2 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EWM28114.1 - 0.024 14.3 6.3 0.024 14.3 4.4 1.7 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_6 PF14835.1 EWM28114.1 - 1.3 8.8 8.0 4.5 7.1 5.6 1.9 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Ribosomal_S9 PF00380.14 EWM28115.1 - 1.7e-40 138.0 0.0 2.8e-40 137.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 tRNA_synt_1c_R2 PF04557.10 EWM28116.1 - 0.09 13.4 1.6 0.19 12.4 0.1 2.1 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 5_3_exonuc_N PF02739.11 EWM28117.1 - 1.5e-25 89.4 0.0 2.3e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.15 EWM28117.1 - 1.5e-20 73.3 0.0 3.2e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.1 EWM28117.1 - 9.6e-06 25.6 0.7 2.1e-05 24.6 0.1 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_2 PF12826.2 EWM28117.1 - 0.00087 19.1 0.0 0.0021 17.9 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPRY PF00622.23 EWM28118.1 - 0.00044 20.3 0.1 0.0009 19.3 0.0 1.5 2 0 0 2 2 2 1 SPRY domain Foie-gras_1 PF11817.3 EWM28119.1 - 3.7e-08 33.1 0.5 8.6e-08 31.9 0.4 1.6 1 0 0 1 1 1 1 Foie gras liver health family 1 TRAPPC10 PF12584.3 EWM28119.1 - 0.00065 19.2 0.0 0.0015 18.0 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 TPR_12 PF13424.1 EWM28119.1 - 0.06 13.2 1.3 0.99 9.3 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat G10 PF01125.12 EWM28120.1 - 0.031 13.8 0.0 0.038 13.5 0.0 1.1 1 0 0 1 1 1 0 G10 protein RPN7 PF10602.4 EWM28121.1 - 2.1e-44 151.0 0.0 3.3e-44 150.3 0.0 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EWM28121.1 - 6.1e-16 58.6 0.0 1.4e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.12 EWM28121.1 - 0.23 11.4 2.7 3.1 7.9 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat RPN7 PF10602.4 EWM28122.1 - 1.9e-44 151.1 0.0 3.2e-44 150.4 0.0 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EWM28122.1 - 5.4e-16 58.8 0.0 1.4e-15 57.5 0.0 1.7 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.12 EWM28122.1 - 0.2 11.6 2.7 3 7.9 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TatD_DNase PF01026.16 EWM28123.1 - 2.6e-41 141.5 0.0 3.9e-41 140.9 0.0 1.2 1 1 0 1 1 1 1 TatD related DNase GTP_EFTU PF00009.22 EWM28125.1 - 8.7e-44 149.2 0.0 1.2e-43 148.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EWM28125.1 - 1.6e-27 95.4 0.0 3.3e-27 94.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EWM28125.1 - 1.4e-22 79.3 0.0 4.1e-22 77.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EWM28125.1 - 6.8e-10 38.9 0.0 1.6e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EWM28125.1 - 3.1e-07 30.1 0.0 7e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EWM28125.1 - 1.6e-05 24.8 0.0 2.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EWM28125.1 - 0.0006 20.3 0.0 0.0012 19.3 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EWM28125.1 - 0.026 13.9 0.0 0.092 12.1 0.0 1.8 1 1 0 1 1 1 0 Ras family Frigida PF07899.6 EWM28125.1 - 0.068 11.9 0.1 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Frigida-like protein Dynamin_N PF00350.18 EWM28125.1 - 0.15 11.9 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 Dynamin family ABM PF03992.11 EWM28126.1 - 6.7e-05 22.8 0.0 9.6e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Pkinase PF00069.20 EWM28127.1 - 1.1e-47 162.4 0.0 1.6e-47 161.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM28127.1 - 3.8e-23 81.9 0.0 5.5e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EWM28127.1 - 9.7e-05 22.2 1.2 0.0038 16.9 0.2 3.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EWM28127.1 - 0.00049 19.1 0.0 0.0015 17.5 0.0 1.8 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EWM28127.1 - 0.01 15.1 0.1 0.035 13.4 0.1 1.8 1 1 1 2 2 2 0 RIO1 family Seadorna_VP7 PF07387.6 EWM28127.1 - 0.17 10.6 0.0 0.27 10.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 HisG PF01634.13 EWM28128.1 - 5.2e-49 165.9 0.1 7.1e-49 165.5 0.1 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 EWM28128.1 - 1.6e-24 85.6 0.0 3e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 EWM28128.1 - 0.0048 16.5 0.0 0.0074 15.8 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like LysR_substrate PF03466.15 EWM28128.1 - 0.021 13.9 0.0 0.047 12.7 0.0 1.5 1 1 0 1 1 1 0 LysR substrate binding domain LRR_6 PF13516.1 EWM28129.1 - 9.4e-11 40.6 1.4 0.00064 19.5 0.0 4.6 4 0 0 4 4 4 3 Leucine Rich repeat LRR_4 PF12799.2 EWM28129.1 - 0.0014 18.2 0.1 0.031 13.9 0.0 2.5 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EWM28129.1 - 0.0059 16.4 0.2 0.67 10.2 0.0 3.3 4 0 0 4 4 4 1 Leucine Rich Repeat ETF PF01012.16 EWM28129.1 - 0.02 14.6 3.4 0.73 9.5 0.1 2.6 2 1 0 2 2 2 0 Electron transfer flavoprotein domain LRR_7 PF13504.1 EWM28129.1 - 0.14 12.4 0.8 1.7 9.1 0.0 3.1 2 0 0 2 2 2 0 Leucine rich repeat TPR_1 PF00515.23 EWM28130.1 - 6.8e-08 31.8 1.0 6.5e-07 28.6 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EWM28130.1 - 7.4e-08 31.7 1.9 4.5e-06 26.1 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EWM28130.1 - 1.1e-07 31.6 0.3 3.2e-07 30.1 0.2 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 EWM28130.1 - 1.8e-07 30.6 0.1 4.5e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 TPR repeat Methyltransf_28 PF02636.12 EWM28130.1 - 1.1e-05 25.0 0.0 4e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase TPR_10 PF13374.1 EWM28130.1 - 4.4e-05 23.2 1.0 0.0017 18.2 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EWM28130.1 - 0.00087 18.9 3.4 0.0041 16.8 0.2 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EWM28130.1 - 0.0048 16.5 0.1 0.021 14.5 0.0 2.2 2 0 0 2 2 1 1 Tetratricopeptide repeat Apc3 PF12895.2 EWM28130.1 - 0.0065 16.5 0.1 0.024 14.7 0.0 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EWM28130.1 - 0.049 14.3 0.3 2.7 8.7 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EWM28130.1 - 0.071 13.7 0.2 2.1 9.2 0.0 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 EWM28130.1 - 0.071 12.9 0.3 0.23 11.3 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EWM28130.1 - 0.74 10.4 0.0 0.74 10.4 0.0 2.9 4 0 0 4 4 2 0 Tetratricopeptide repeat SKIP_SNW PF02731.10 EWM28131.1 - 7.4e-60 200.9 3.2 7.4e-60 200.9 2.2 1.6 2 0 0 2 2 2 1 SKIP/SNW domain DUF2756 PF10956.3 EWM28131.1 - 0.068 13.4 1.3 7.1 6.9 0.1 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF2756) G6B PF15096.1 EWM28132.1 - 0.019 14.4 0.0 0.047 13.1 0.0 1.6 1 0 0 1 1 1 0 G6B family NAD_binding_2 PF03446.10 EWM28133.1 - 8.5e-27 93.9 0.1 1.3e-26 93.3 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EWM28133.1 - 6.6e-07 28.6 0.0 9.1e-07 28.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_11 PF14833.1 EWM28133.1 - 7e-07 29.3 1.9 8.7e-07 29.0 0.2 2.0 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase IlvN PF07991.7 EWM28133.1 - 3.1e-05 23.4 0.0 5.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EWM28133.1 - 0.00017 21.9 0.0 0.00054 20.3 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EWM28133.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Mpv17_PMP22 PF04117.7 EWM28134.1 - 3.3e-22 77.8 0.1 5.8e-22 77.1 0.1 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family RRM_1 PF00076.17 EWM28135.1 - 3.1e-21 74.7 0.0 5.3e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM28135.1 - 5.3e-12 45.5 0.1 9.5e-12 44.7 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM28135.1 - 3.3e-07 30.0 0.1 7.1e-07 28.9 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Exo_endo_phos PF03372.18 EWM28136.1 - 1.4e-18 67.7 0.0 2.8e-18 66.7 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family T2SM_b PF10741.4 EWM28136.1 - 0.06 12.9 0.1 0.58 9.7 0.0 2.4 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein M subtype b Peptidase_S28 PF05577.7 EWM28137.1 - 2.8e-79 266.7 0.0 3.4e-79 266.4 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 EWM28137.1 - 7e-09 35.8 0.4 1.3e-08 34.9 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EWM28137.1 - 1.6e-07 31.1 0.0 3.1e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S37 PF05576.6 EWM28137.1 - 8.8e-06 24.4 0.0 1.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 PS-10 peptidase S37 Abhydrolase_5 PF12695.2 EWM28137.1 - 0.008 15.9 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2920 PF11144.3 EWM28137.1 - 0.014 14.3 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Peptidase_S9 PF00326.16 EWM28137.1 - 0.024 13.8 0.0 0.056 12.6 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family Glyoxalase_4 PF13669.1 EWM28137.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily HSA PF07529.8 EWM28137.1 - 0.59 9.9 4.6 1.1 9.1 1.0 2.2 2 0 0 2 2 2 0 HSA TPR_11 PF13414.1 EWM28138.1 - 3e-08 33.1 0.1 1.1e-05 24.9 0.1 3.3 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.1 EWM28138.1 - 3.4e-06 27.5 2.5 0.0026 18.3 0.1 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EWM28138.1 - 3.2e-05 23.7 1.6 0.087 12.7 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EWM28138.1 - 0.00011 21.8 7.0 0.9 9.6 0.0 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EWM28138.1 - 0.0012 19.0 0.0 0.5 10.7 0.0 3.4 1 1 1 2 2 2 1 Tetratricopeptide repeat PHD PF00628.24 EWM28138.1 - 0.0018 17.8 12.9 0.0046 16.6 8.9 1.7 1 0 0 1 1 1 1 PHD-finger TPR_14 PF13428.1 EWM28138.1 - 0.012 16.1 13.3 0.94 10.2 0.0 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EWM28138.1 - 0.019 14.5 1.2 1.3 8.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Vma12 PF11712.3 EWM28139.1 - 6.2e-10 38.9 0.0 1e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase CopD PF05425.8 EWM28139.1 - 0.017 15.3 0.4 0.026 14.7 0.3 1.3 1 0 0 1 1 1 0 Copper resistance protein D DUF2207 PF09972.4 EWM28139.1 - 0.12 10.9 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RmlD_sub_bind PF04321.12 EWM28140.1 - 6.7e-06 25.1 0.0 1.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EWM28140.1 - 0.00023 20.6 0.0 0.00043 19.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Adaptin_N PF01602.15 EWM28142.1 - 3e-111 372.3 0.0 4e-111 371.9 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EWM28142.1 - 1.2e-07 31.8 1.1 0.012 15.9 0.1 4.4 3 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.2 EWM28142.1 - 1.4e-06 28.2 4.2 0.00036 20.4 0.2 3.2 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 EWM28142.1 - 0.0015 18.3 2.3 1.5 8.7 0.1 4.5 3 1 1 4 4 4 1 Protein of unknown function (DUF2435) HEAT PF02985.17 EWM28142.1 - 0.057 13.5 6.3 9.7 6.5 0.0 5.3 6 0 0 6 6 6 0 HEAT repeat RasGEF_N_2 PF14663.1 EWM28142.1 - 0.21 11.5 1.2 7.7 6.4 0.1 2.8 2 1 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Metallophos PF00149.23 EWM28143.1 - 7.4e-13 48.3 0.0 1.4e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EWM28143.1 - 6.6e-09 35.7 0.0 1.1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain GKAP PF03359.8 EWM28143.1 - 0.063 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein Metallophos_3 PF14582.1 EWM28143.1 - 0.084 12.0 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily PCI PF01399.22 EWM28145.1 - 3.4e-06 27.3 0.0 6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 PCI domain Paf67 PF10255.4 EWM28145.1 - 0.26 10.1 0.1 0.46 9.3 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 polyprenyl_synt PF00348.12 EWM28148.1 - 4e-54 183.1 0.0 5.3e-54 182.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 EWM28148.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Glu_cyclase_2 PF05096.7 EWM28149.1 - 6.6e-64 215.4 0.1 8.7e-64 215.0 0.1 1.0 1 0 0 1 1 1 1 Glutamine cyclotransferase PQQ_2 PF13360.1 EWM28149.1 - 0.0046 16.4 0.2 0.2 11.0 0.1 2.7 1 1 1 2 2 2 2 PQQ-like domain PepSY PF03413.14 EWM28149.1 - 0.035 14.7 0.1 3.1 8.5 0.0 2.4 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain SGL PF08450.7 EWM28149.1 - 0.066 12.5 0.2 2.2 7.5 0.1 2.5 2 1 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region PCI_Csn8 PF10075.4 EWM28150.1 - 2.2e-21 76.1 0.0 3.7e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EWM28150.1 - 2.5e-18 66.3 0.0 3.2e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DnaJ PF00226.26 EWM28151.1 - 4.7e-20 71.0 0.7 6.9e-20 70.5 0.5 1.3 1 0 0 1 1 1 1 DnaJ domain Tmemb_185A PF10269.4 EWM28151.1 - 2.3e-12 47.0 30.5 2e-07 30.8 4.3 3.6 1 1 0 2 2 2 2 Transmembrane Fragile-X-F protein BTB PF00651.26 EWM28152.1 - 5.8e-19 68.1 0.0 3e-09 36.8 0.0 4.5 3 1 1 4 4 4 3 BTB/POZ domain Ank_4 PF13637.1 EWM28152.1 - 3.8e-09 36.8 0.3 1.7e-08 34.7 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EWM28152.1 - 6.3e-09 36.0 0.0 1.7e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EWM28152.1 - 1.1e-08 34.4 0.1 0.00014 21.4 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EWM28152.1 - 6.3e-05 23.0 0.1 0.0017 18.5 0.2 3.0 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM28152.1 - 0.00071 19.5 0.4 0.15 12.4 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat DUF3652 PF12372.3 EWM28152.1 - 0.012 15.2 0.1 0.026 14.1 0.1 1.6 1 0 0 1 1 1 0 Huntingtin protein region C2-set PF05790.10 EWM28152.1 - 0.13 12.2 0.0 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin C2-set domain B3_4 PF03483.12 EWM28153.1 - 9.4e-21 74.0 0.0 1.6e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EWM28153.1 - 5.1e-15 55.0 0.0 8.1e-13 48.0 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain tRNA-synt_2d PF01409.15 EWM28153.1 - 0.12 11.5 0.0 0.4 9.8 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) ketoacyl-synt PF00109.21 EWM28154.1 - 7.2e-59 199.3 0.1 1.1e-58 198.7 0.1 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EWM28154.1 - 1.2e-27 96.0 0.7 2.5e-27 95.0 0.5 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EWM28154.1 - 3.2e-05 23.0 0.1 5.4e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF965 PF06135.7 EWM28154.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF965) NTP_transf_2 PF01909.18 EWM28155.1 - 1.7e-08 34.6 0.0 3.6e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 EWM28155.1 - 1.7e-08 34.2 1.1 2.8e-07 30.3 0.7 2.7 1 1 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EWM28156.1 - 1.7e-08 34.6 0.0 3.6e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 EWM28156.1 - 1.7e-08 34.2 1.1 2.8e-07 30.3 0.7 2.7 1 1 0 1 1 1 1 Cid1 family poly A polymerase Mito_carr PF00153.22 EWM28157.1 - 1.3e-58 194.6 0.7 9.2e-21 73.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Methyltransf_4 PF02390.12 EWM28158.1 - 6.4e-48 162.4 0.0 7.7e-48 162.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EWM28158.1 - 1.3e-07 31.6 0.0 2.4e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM28158.1 - 6.2e-06 26.7 0.0 1.4e-05 25.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EWM28158.1 - 2.3e-05 23.8 0.0 4.9e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain FmrO PF07091.6 EWM28158.1 - 0.0017 17.3 0.0 0.0038 16.2 0.0 1.5 2 0 0 2 2 2 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_31 PF13847.1 EWM28158.1 - 0.0055 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM28158.1 - 0.0089 16.4 0.0 0.04 14.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM28158.1 - 0.01 16.2 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF2431 PF10354.4 EWM28158.1 - 0.012 15.6 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) Methyltransf_25 PF13649.1 EWM28158.1 - 0.024 14.9 0.0 0.041 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EWM28158.1 - 0.029 13.8 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 EWM28158.1 - 0.053 13.2 0.3 1.3 8.7 0.2 2.2 1 1 0 1 1 1 0 Methyltransferase domain UCH PF00443.24 EWM28159.1 - 1.7e-12 47.0 0.0 2.4e-12 46.5 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EWM28159.1 - 0.0042 16.5 6.7 0.086 12.2 4.6 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CoaE PF01121.15 EWM28160.1 - 2.6e-42 144.2 0.0 3.2e-42 143.9 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 EWM28160.1 - 0.14 12.9 0.1 0.47 11.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain ANTAR PF03861.9 EWM28160.1 - 0.62 9.6 6.5 2 8.0 1.0 2.4 1 1 1 2 2 2 0 ANTAR domain DUF4395 PF14340.1 EWM28161.1 - 0.22 11.6 8.9 0.63 10.1 6.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4395) Acyl_transf_3 PF01757.17 EWM28162.1 - 7.4e-19 67.7 31.5 7.4e-19 67.7 21.9 2.2 3 0 0 3 3 3 1 Acyltransferase family OppC_N PF12911.2 EWM28162.1 - 0.079 12.3 5.6 1.8 8.0 0.1 3.9 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C DUF2275 PF10039.4 EWM28162.1 - 3.7 7.3 5.8 4.2 7.2 0.1 2.9 3 0 0 3 3 3 0 Predicted integral membrane protein (DUF2275) DNA_pol_A_exo1 PF01612.15 EWM28163.1 - 3.6e-18 65.6 0.0 5.2e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease F_actin_cap_B PF01115.12 EWM28164.1 - 2.1e-69 233.4 0.0 2.5e-69 233.1 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Sulf_transp PF04143.9 EWM28165.1 - 3e-18 65.5 12.5 5.3e-12 45.5 3.1 4.3 4 0 0 4 4 4 2 Sulphur transport DUF4341 PF14241.1 EWM28165.1 - 9.2e-08 31.6 6.4 9.2e-08 31.6 4.5 4.6 5 2 0 5 5 5 1 Domain of unknown function (DUF4341) Pox_MCEL PF03291.11 EWM28166.1 - 4.2e-38 131.0 0.0 6.6e-32 110.6 0.0 2.8 2 1 0 2 2 2 2 mRNA capping enzyme Methyltransf_11 PF08241.7 EWM28166.1 - 5.5e-06 26.7 0.1 8.9e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM28166.1 - 1e-05 25.9 0.0 3.7e-05 24.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM28166.1 - 1.5e-05 25.5 0.0 2.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM28166.1 - 0.00017 21.1 0.0 0.00074 19.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM28166.1 - 0.00031 21.0 0.0 0.00061 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Oxidored_q1_N PF00662.15 EWM28166.1 - 0.14 11.7 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Mito_carr PF00153.22 EWM28167.1 - 1.2e-44 149.9 1.2 1.7e-14 53.3 0.1 3.9 3 2 0 3 3 3 3 Mitochondrial carrier protein ABC2_membrane PF01061.19 EWM28168.1 - 4.2e-35 120.8 10.0 4.2e-35 120.8 7.0 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 EWM28168.1 - 9.5e-21 74.5 0.0 1.5e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EWM28168.1 - 2.2e-06 27.8 0.0 1.3e-05 25.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EWM28168.1 - 0.00019 20.9 0.1 0.00043 19.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC2_membrane_2 PF12679.2 EWM28168.1 - 0.00047 19.1 3.3 0.00047 19.1 2.3 1.6 1 1 1 2 2 2 1 ABC-2 family transporter protein DUF258 PF03193.11 EWM28168.1 - 0.0039 16.4 0.0 0.007 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EWM28168.1 - 0.032 14.2 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 EWM28168.1 - 0.063 12.6 0.0 0.18 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.2 EWM28168.1 - 0.16 10.9 21.9 0.19 10.7 14.0 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein ABC2_membrane_4 PF12730.2 EWM28168.1 - 2.6 7.1 17.5 0.21 10.7 7.8 2.2 1 1 1 2 2 2 0 ABC-2 family transporter protein Radical_SAM PF04055.16 EWM28169.1 - 2e-10 41.1 0.0 3.1e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily ABC2_membrane PF01061.19 EWM28170.1 - 4.5e-32 110.9 23.0 6.3e-32 110.4 16.0 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EWM28170.1 - 1.4e-24 86.9 0.0 2.5e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 EWM28170.1 - 7.5e-11 41.6 15.9 7.5e-11 41.6 11.0 1.6 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA_16 PF13191.1 EWM28170.1 - 1.3e-07 31.8 0.4 4.2e-06 26.8 0.2 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 EWM28170.1 - 7.2e-06 26.1 0.0 0.01 15.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EWM28170.1 - 0.052 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EWM28170.1 - 0.15 11.5 0.1 0.29 10.6 0.1 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 EWM28170.1 - 0.23 11.7 0.0 0.39 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EWM28171.1 - 8.4e-38 129.5 0.0 3.1e-37 127.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EWM28171.1 - 5.4e-05 23.0 0.0 0.00016 21.5 0.0 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_33 PF13671.1 EWM28171.1 - 5.8e-05 23.0 0.2 0.0023 17.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EWM28171.1 - 7.1e-05 21.9 0.0 0.00014 20.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EWM28171.1 - 0.00037 19.9 0.1 0.0014 18.0 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.1 EWM28171.1 - 0.00048 20.2 0.8 0.002 18.2 0.0 2.4 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EWM28171.1 - 0.00069 19.3 0.0 0.0038 16.9 0.0 2.3 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EWM28171.1 - 0.00073 19.2 0.0 0.0072 16.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MIT PF04212.13 EWM28171.1 - 0.0012 18.6 1.3 0.0012 18.6 0.9 2.1 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 EWM28171.1 - 0.0026 18.5 0.1 0.01 16.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EWM28171.1 - 0.0028 16.8 0.0 0.0055 15.8 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 EWM28171.1 - 0.0028 16.4 0.0 0.0048 15.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 EWM28171.1 - 0.0034 16.8 1.8 0.011 15.1 0.2 2.4 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EWM28171.1 - 0.0041 17.1 0.7 0.041 13.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 EWM28171.1 - 0.0044 16.9 0.0 0.016 15.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EWM28171.1 - 0.0071 16.2 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EWM28171.1 - 0.0079 15.8 0.1 0.021 14.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EWM28171.1 - 0.0079 16.5 0.4 0.047 13.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EWM28171.1 - 0.022 14.3 0.0 0.053 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EWM28171.1 - 0.026 14.4 0.0 0.094 12.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EWM28171.1 - 0.035 13.2 0.0 0.12 11.4 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.7 EWM28171.1 - 0.035 13.7 0.0 0.093 12.3 0.0 1.7 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 EWM28171.1 - 0.037 14.2 0.0 0.089 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.11 EWM28171.1 - 0.051 12.8 0.0 0.091 11.9 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 EWM28171.1 - 0.14 11.0 0.2 0.31 9.8 0.0 1.6 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 NMT_C PF02799.10 EWM28172.1 - 9.8e-71 237.0 0.0 1.4e-70 236.5 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 EWM28172.1 - 1.2e-70 236.3 0.1 2.3e-70 235.4 0.0 1.5 1 1 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.1 EWM28172.1 - 0.011 15.5 0.0 0.032 14.0 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EWM28172.1 - 0.092 12.9 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Arf PF00025.16 EWM28173.1 - 4.3e-62 208.4 0.0 4.9e-62 208.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EWM28173.1 - 2.7e-09 36.6 0.0 3.4e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EWM28173.1 - 2.8e-09 37.5 0.0 3.6e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 EWM28173.1 - 9.2e-09 34.4 0.2 1.9e-05 23.5 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EWM28173.1 - 1.9e-08 33.7 0.0 2.4e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EWM28173.1 - 4.3e-06 26.6 0.0 5.8e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EWM28173.1 - 0.00014 21.1 0.0 0.00015 21.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EWM28173.1 - 0.00038 19.9 0.0 0.027 13.8 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EWM28173.1 - 0.012 15.1 0.0 0.026 14.0 0.0 1.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ANT PF03374.9 EWM28173.1 - 0.023 14.7 0.0 0.038 14.0 0.0 1.2 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain cobW PF02492.14 EWM28173.1 - 0.041 13.3 0.0 3.5 7.0 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.13 EWM28173.1 - 0.12 11.5 0.1 0.42 9.8 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.1 EWM28173.1 - 0.13 12.3 0.0 0.31 11.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain Antibiotic_NAT PF02522.9 EWM28173.1 - 0.14 11.3 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside 3-N-acetyltransferase Peptidase_S8 PF00082.17 EWM28174.1 - 1.1e-57 195.2 0.7 1.6e-57 194.8 0.5 1.2 1 0 0 1 1 1 1 Subtilase family 2OG-FeII_Oxy_2 PF13532.1 EWM28175.1 - 3.2e-16 59.7 0.0 4.7e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EWM28175.1 - 3.1e-09 36.9 0.0 6.2e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Mito_fiss_reg PF05308.6 EWM28177.1 - 0.24 10.7 2.1 0.27 10.5 1.5 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator ABC2_membrane_3 PF12698.2 EWM28178.1 - 2.6e-59 201.0 47.1 8.7e-40 136.7 9.9 3.1 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.22 EWM28178.1 - 1.5e-55 187.2 0.0 3.3e-30 105.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EWM28178.1 - 5e-19 69.3 0.0 3.1e-06 27.3 0.0 4.3 3 1 0 3 3 3 3 AAA domain AAA_29 PF13555.1 EWM28178.1 - 2.4e-05 23.7 1.8 0.0021 17.5 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC2_membrane_4 PF12730.2 EWM28178.1 - 0.00011 21.4 9.5 0.00011 21.4 6.6 3.1 3 0 0 3 3 3 1 ABC-2 family transporter protein DUF258 PF03193.11 EWM28178.1 - 0.00023 20.3 0.1 0.0046 16.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_15 PF13175.1 EWM28178.1 - 0.0014 17.7 0.0 1.8 7.5 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.1 EWM28178.1 - 0.0017 18.7 3.1 0.062 13.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EWM28178.1 - 0.014 14.6 0.1 7.4 5.7 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.16 EWM28178.1 - 0.025 13.7 0.7 1.1 8.3 0.0 3.2 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 EWM28178.1 - 0.027 14.0 0.1 0.68 9.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EWM28178.1 - 0.031 14.2 0.0 5 7.1 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase SRP54 PF00448.17 EWM28178.1 - 0.06 12.7 3.4 2.3 7.5 0.1 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain SbcCD_C PF13558.1 EWM28178.1 - 0.085 12.7 0.0 34 4.4 0.0 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 EWM28178.1 - 0.096 12.0 0.5 4 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Glyco_hydro_17 PF00332.13 EWM28178.1 - 0.41 9.6 0.0 0.72 8.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 Zeta_toxin PF06414.7 EWM28178.1 - 0.62 9.1 0.1 36 3.3 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_13 PF13166.1 EWM28178.1 - 2.3 6.5 0.4 14 3.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain NIT PF08376.5 EWM28179.1 - 0.023 14.2 0.6 0.044 13.2 0.2 1.6 2 0 0 2 2 2 0 Nitrate and nitrite sensing DUF2694 PF10904.3 EWM28179.1 - 0.11 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2694) NIT PF08376.5 EWM28180.1 - 0.013 15.0 0.1 0.022 14.3 0.1 1.4 1 0 0 1 1 1 0 Nitrate and nitrite sensing DUF2694 PF10904.3 EWM28180.1 - 0.047 13.6 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2694) NACHT PF05729.7 EWM28181.1 - 7.8e-10 38.6 0.0 1.4e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain SH2 PF00017.19 EWM28181.1 - 1.3e-09 37.6 0.1 2.7e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 SH2 domain CHAT PF12770.2 EWM28181.1 - 3.9e-08 32.7 0.1 7.7e-08 31.8 0.1 1.4 1 0 0 1 1 1 1 CHAT domain NB-ARC PF00931.17 EWM28181.1 - 1e-06 27.8 0.0 1.8e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 EWM28181.1 - 2.4e-06 27.6 0.0 8.1e-06 25.9 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 EWM28181.1 - 0.00068 19.3 0.0 0.0016 18.2 0.0 1.7 1 0 0 1 1 1 1 Archaeal ATPase AAA PF00004.24 EWM28181.1 - 0.00098 19.3 0.0 0.0028 17.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EWM28181.1 - 0.001 18.7 0.0 0.0033 17.1 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 EWM28181.1 - 0.002 16.8 0.0 0.0033 16.2 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_22 PF13401.1 EWM28181.1 - 0.0022 18.1 0.0 0.0064 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EWM28181.1 - 0.0072 17.1 0.0 0.019 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EWM28181.1 - 0.012 15.7 0.0 0.024 14.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.10 EWM28181.1 - 0.022 14.4 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 NTPase DnaB_C PF03796.10 EWM28181.1 - 0.044 12.6 0.0 0.078 11.8 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain DUF2075 PF09848.4 EWM28181.1 - 0.075 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATP-synt_ab PF00006.20 EWM28181.1 - 0.11 11.9 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain KAP_NTPase PF07693.9 EWM28181.1 - 0.25 10.2 0.0 0.41 9.5 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain DUF883 PF05957.8 EWM28182.1 - 0.016 15.5 6.4 0.23 11.8 1.0 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Dak2 PF02734.12 EWM28182.1 - 0.022 14.4 2.2 0.025 14.2 1.6 1.2 1 0 0 1 1 1 0 DAK2 domain YtxH PF12732.2 EWM28182.1 - 0.031 14.6 3.5 1.9 8.9 2.4 2.2 1 1 0 1 1 1 0 YtxH-like protein ApoLp-III PF07464.6 EWM28182.1 - 0.05 13.6 1.5 0.073 13.1 1.0 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) EBP50_C-term PF09007.6 EWM28182.1 - 0.5 10.2 0.1 0.5 10.2 0.1 2.3 3 0 0 3 3 3 0 EBP50, C-terminal DUF4398 PF14346.1 EWM28182.1 - 1.4 9.0 9.4 6 6.9 6.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4398) MxiH PF09392.5 EWM28182.1 - 3.4 8.2 5.5 11 6.6 3.8 1.8 1 1 0 1 1 1 0 Type III secretion needle MxiH like YihI PF04220.7 EWM28182.1 - 3.4 6.9 7.1 4.6 6.5 4.9 1.2 1 0 0 1 1 1 0 Der GTPase activator (YihI) Chloroa_b-bind PF00504.16 EWM28183.1 - 8.6e-31 107.3 0.0 1.1e-30 106.9 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DSPc PF00782.15 EWM28184.1 - 3.9e-26 91.1 0.0 6.9e-26 90.4 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EWM28184.1 - 0.0004 19.8 0.0 0.00055 19.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EWM28184.1 - 0.00067 19.7 0.1 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Glutaredoxin2_C PF04399.8 EWM28187.1 - 1.3e-21 76.5 0.0 1.7e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain GST_N_3 PF13417.1 EWM28187.1 - 2.6e-10 40.3 0.0 6e-10 39.2 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EWM28187.1 - 1.1e-07 31.6 0.0 2.3e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 EWM28187.1 - 0.0092 15.9 0.0 0.024 14.6 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin SOUL PF04832.7 EWM28188.1 - 2.1e-43 147.8 0.2 1.1e-42 145.5 0.1 2.0 1 1 0 1 1 1 1 SOUL heme-binding protein SOUL PF04832.7 EWM28189.1 - 2.1e-43 147.8 0.2 1.1e-42 145.5 0.1 2.0 1 1 0 1 1 1 1 SOUL heme-binding protein DEAD PF00270.24 EWM28190.1 - 2e-19 69.7 0.0 4.8e-19 68.4 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EWM28190.1 - 5.3e-16 58.2 0.0 1.5e-15 56.7 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EWM28190.1 - 0.0014 18.5 0.0 0.0027 17.5 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2811 PF10929.3 EWM28190.1 - 0.074 13.0 0.0 21 5.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2811) GTP_cyclohydroI PF01227.17 EWM28191.1 - 3e-76 254.6 0.5 4.5e-76 254.1 0.4 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EWM28191.1 - 0.0016 18.3 0.0 0.0028 17.5 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein Hist_rich_Ca-bd PF10529.4 EWM28191.1 - 0.027 14.4 3.4 0.027 14.4 2.4 2.4 2 0 0 2 2 2 0 Histidine-rich Calcium-binding repeat region Ku_N PF03731.10 EWM28192.1 - 3.7e-21 75.6 0.0 1e-20 74.1 0.0 1.7 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.11 EWM28192.1 - 7.8e-21 74.4 0.0 1.2e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain SAP PF02037.22 EWM28192.1 - 8.9e-10 37.8 2.5 2.1e-09 36.6 1.7 1.7 1 0 0 1 1 1 1 SAP domain AKNA PF12443.3 EWM28192.1 - 0.028 14.4 0.7 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 AT-hook-containing transcription factor Ku_C PF03730.9 EWM28192.1 - 0.069 13.6 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 Ku70/Ku80 C-terminal arm 6PF2K PF01591.13 EWM28193.1 - 1.2e-53 181.5 0.0 1.7e-53 180.9 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EWM28193.1 - 9.7e-27 93.9 0.0 1.6e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EWM28193.1 - 5.7e-08 32.7 0.0 1e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EWM28193.1 - 6.7e-05 23.6 1.9 0.00018 22.2 0.3 2.4 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EWM28193.1 - 0.00091 19.5 0.0 0.015 15.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 EWM28193.1 - 0.016 14.4 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_22 PF13401.1 EWM28193.1 - 0.086 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain DER1 PF04511.10 EWM28194.1 - 7.1e-55 185.5 9.4 9e-55 185.2 6.5 1.1 1 0 0 1 1 1 1 Der1-like family Fer2 PF00111.22 EWM28195.1 - 2.8e-08 33.4 1.7 4.8e-08 32.6 1.2 1.5 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain PTS-HPr PF00381.14 EWM28195.1 - 0.0024 17.7 0.1 0.0072 16.1 0.0 1.8 2 1 0 2 2 2 1 PTS HPr component phosphorylation site Cupredoxin_1 PF13473.1 EWM28195.1 - 0.022 14.6 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 Cupredoxin-like domain GMC_oxred_N PF00732.14 EWM28196.1 - 6.2e-70 235.6 0.0 7.3e-38 130.3 0.0 2.2 1 1 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EWM28196.1 - 1.3e-35 122.7 0.0 2e-35 122.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EWM28196.1 - 7.9e-05 21.6 0.1 0.035 12.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EWM28196.1 - 0.00023 20.2 0.0 0.00033 19.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EWM28196.1 - 0.00023 20.1 0.6 0.0013 17.7 0.1 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EWM28196.1 - 0.0011 18.9 0.1 0.005 16.8 0.1 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EWM28196.1 - 0.048 13.5 0.0 0.095 12.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EWM28196.1 - 0.075 12.1 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EWM28196.1 - 0.096 11.1 0.0 0.14 10.5 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein TPR_14 PF13428.1 EWM28197.1 - 3.4e-31 104.8 40.5 0.0011 19.3 0.0 14.6 7 4 10 17 17 16 11 Tetratricopeptide repeat PRP1_N PF06424.7 EWM28197.1 - 2.5e-23 82.8 1.5 6e-23 81.6 1.0 1.6 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_19 PF14559.1 EWM28197.1 - 6.8e-18 64.7 17.8 5.5e-06 26.6 0.1 10.7 8 3 5 14 14 13 3 Tetratricopeptide repeat TPR_16 PF13432.1 EWM28197.1 - 2.1e-17 63.3 32.4 0.00012 22.6 1.2 9.5 8 2 1 10 10 9 6 Tetratricopeptide repeat TPR_11 PF13414.1 EWM28197.1 - 8.6e-15 54.1 11.3 0.031 13.9 0.0 8.9 6 3 5 11 11 11 4 TPR repeat TPR_17 PF13431.1 EWM28197.1 - 2e-12 46.2 0.7 3.2 8.1 0.0 10.2 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_2 PF07719.12 EWM28197.1 - 8e-10 37.8 17.1 0.0035 17.1 0.0 9.8 13 0 0 13 13 12 2 Tetratricopeptide repeat TPR_8 PF13181.1 EWM28197.1 - 3.9e-07 29.3 0.0 6 6.8 0.0 7.1 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 EWM28197.1 - 1.8e-05 24.1 1.8 0.26 10.9 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EWM28197.1 - 0.0016 18.7 10.8 31 5.2 0.0 8.6 10 0 0 10 10 8 0 Tetratricopeptide repeat MIT PF04212.13 EWM28197.1 - 0.0072 16.1 6.3 2.6 7.9 0.0 5.3 5 1 1 6 6 6 1 MIT (microtubule interacting and transport) domain TPR_12 PF13424.1 EWM28197.1 - 0.045 13.7 16.6 1.6 8.7 0.0 6.8 6 1 2 8 8 7 0 Tetratricopeptide repeat Suf PF05843.9 EWM28197.1 - 0.063 13.0 0.0 8.1 6.0 0.0 3.7 2 1 0 3 3 3 0 Suppressor of forked protein (Suf) FAT PF02259.18 EWM28197.1 - 0.9 8.4 9.6 4.9 6.0 0.3 3.9 1 1 3 4 4 4 0 FAT domain PseudoU_synth_2 PF00849.17 EWM28198.1 - 1.2e-24 86.9 0.0 2.1e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 EWM28198.1 - 1.1e-06 27.9 0.0 2.4e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 S4 domain PA-IL PF07828.7 EWM28198.1 - 0.013 15.2 0.1 0.025 14.3 0.1 1.5 1 0 0 1 1 1 0 PA-IL-like protein RRM_1 PF00076.17 EWM28200.1 - 2.2e-22 78.4 0.0 4.4e-12 45.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM28200.1 - 3.3e-21 75.0 0.0 7e-10 38.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM28200.1 - 1.5e-10 40.7 0.0 5.7e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_4 PF15227.1 EWM28200.1 - 9.7e-09 34.9 6.7 1.7e-08 34.1 4.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EWM28200.1 - 1.1e-07 31.3 5.5 1.9e-07 30.6 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EWM28200.1 - 4.1e-07 29.5 4.4 7.8e-07 28.6 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EWM28200.1 - 1e-05 25.4 6.9 1.8e-05 24.6 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EWM28200.1 - 1.7e-05 24.5 7.2 3e-05 23.7 5.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EWM28200.1 - 1.8e-05 24.3 4.8 3.2e-05 23.5 3.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain RNA_bind PF08675.6 EWM28200.1 - 0.0024 17.8 0.0 0.062 13.2 0.0 2.2 2 0 0 2 2 2 1 RNA binding domain zf-RING_UBOX PF13445.1 EWM28200.1 - 0.0032 17.1 4.7 0.0076 15.9 3.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.15 EWM28200.1 - 0.055 12.9 5.4 0.096 12.2 3.8 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_4 PF14570.1 EWM28200.1 - 0.2 11.2 1.9 0.22 11.1 0.3 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_3 PF14369.1 EWM28200.1 - 0.2 11.6 4.5 3.4 7.7 0.9 2.7 2 0 0 2 2 2 0 zinc-finger Methyltransf_11 PF08241.7 EWM28201.1 - 6e-19 68.3 0.0 1e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM28201.1 - 2.7e-13 50.1 0.0 5.1e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM28201.1 - 2e-12 47.6 0.0 3.4e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM28201.1 - 7.9e-12 45.5 0.0 1.3e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EWM28201.1 - 1.5e-11 43.9 0.0 2.1e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EWM28201.1 - 1e-10 41.6 0.4 1.7e-10 40.9 0.3 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM28201.1 - 1.5e-09 37.5 0.0 2.9e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM28201.1 - 2.7e-09 36.9 0.0 4.1e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Rsm22 PF09243.5 EWM28201.1 - 0.00012 21.2 0.0 0.00018 20.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 MTS PF05175.9 EWM28201.1 - 0.00012 21.4 0.0 0.00079 18.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.1 EWM28201.1 - 0.00096 19.9 0.0 0.0017 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EWM28201.1 - 0.016 14.8 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase PCMT PF01135.14 EWM28201.1 - 0.04 13.4 0.0 0.07 12.6 0.0 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 EWM28201.1 - 0.063 12.3 0.0 0.25 10.3 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_2 PF00891.13 EWM28201.1 - 0.1 11.8 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase ABC1 PF03109.11 EWM28203.1 - 2.3e-31 108.2 0.0 4.9e-31 107.1 0.0 1.6 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.20 EWM28203.1 - 5.5e-05 22.4 0.0 0.00022 20.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 EWM28203.1 - 0.00047 19.9 0.3 0.00047 19.9 0.2 2.8 2 1 0 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.17 EWM28203.1 - 0.028 13.7 0.0 0.12 11.6 0.0 2.0 2 0 0 2 2 2 0 RIO1 family C2 PF00168.25 EWM28204.1 - 5.1e-10 39.0 0.0 7.5e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 C2 domain CTP_transf_2 PF01467.21 EWM28205.1 - 7.2e-22 78.1 0.0 7.2e-14 52.1 0.0 2.4 2 0 0 2 2 2 2 Cytidylyltransferase FAD_syn PF06574.7 EWM28205.1 - 0.0044 16.6 0.4 6.1 6.4 0.0 3.1 2 1 0 2 2 2 2 FAD synthetase TAFII55_N PF04658.8 EWM28205.1 - 0.15 11.5 0.0 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 TAFII55 protein conserved region Met_gamma_lyase PF06838.6 EWM28206.1 - 1.5e-153 510.9 0.0 2.5e-153 510.1 0.0 1.3 1 1 0 1 1 1 1 Methionine gamma-lyase Aminotran_1_2 PF00155.16 EWM28206.1 - 0.00012 21.1 0.0 0.039 12.8 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EWM28206.1 - 0.00025 19.4 0.0 0.23 9.7 0.0 2.1 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EWM28206.1 - 0.089 11.9 0.0 1.9 7.5 0.0 2.1 2 0 0 2 2 2 0 Beta-eliminating lyase DAGAT PF03982.8 EWM28207.1 - 7.7e-34 116.7 0.0 1e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.16 EWM28207.1 - 0.0025 17.2 0.0 0.0051 16.2 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Tom7 PF08038.7 EWM28207.1 - 0.0038 16.6 0.1 0.012 15.0 0.1 1.9 1 0 0 1 1 1 1 TOM7 family PH PF00169.24 EWM28208.1 - 0.00089 19.4 0.0 0.0022 18.1 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 EWM28208.1 - 0.0023 18.0 0.0 0.0052 16.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.1 EWM28208.1 - 0.15 12.0 0.0 0.44 10.6 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain PPR_2 PF13041.1 EWM28211.1 - 4e-55 183.5 0.0 3.6e-06 26.8 0.0 16.0 10 4 7 17 17 17 12 PPR repeat family PPR_3 PF13812.1 EWM28211.1 - 8.1e-53 172.3 34.0 1.1e-06 28.4 0.0 19.1 20 0 0 20 20 20 12 Pentatricopeptide repeat domain PPR PF01535.15 EWM28211.1 - 1.4e-49 162.6 17.6 0.0028 17.5 0.0 19.5 20 1 0 20 20 20 11 PPR repeat PPR_1 PF12854.2 EWM28211.1 - 5.5e-16 57.7 7.8 0.053 13.0 0.0 10.0 9 0 0 9 9 9 4 PPR repeat TPR_12 PF13424.1 EWM28211.1 - 4.2e-08 33.0 9.1 0.0051 16.7 0.1 6.7 5 2 3 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 EWM28211.1 - 0.00029 21.0 24.2 1.8 8.9 0.4 9.3 9 2 1 10 10 9 2 Tetratricopeptide repeat TPR_7 PF13176.1 EWM28211.1 - 0.01 15.5 9.5 33 4.5 0.0 7.0 6 0 0 6 6 6 0 Tetratricopeptide repeat ECSIT PF06239.6 EWM28211.1 - 0.017 14.0 0.0 47 2.7 0.0 4.4 3 1 1 4 4 4 0 Evolutionarily conserved signalling intermediate in Toll pathway TPR_2 PF07719.12 EWM28211.1 - 0.018 14.9 11.4 54 4.0 0.0 6.7 6 0 0 6 6 5 0 Tetratricopeptide repeat Rcd1 PF04078.8 EWM28211.1 - 0.11 11.2 0.0 0.21 10.3 0.0 1.4 1 0 0 1 1 1 0 Cell differentiation family, Rcd1-like MRP-S27 PF10037.4 EWM28211.1 - 0.22 10.3 0.0 4.7 6.0 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 TPR_10 PF13374.1 EWM28211.1 - 0.48 10.4 20.9 29 4.7 0.5 8.0 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_14 PF13428.1 EWM28211.1 - 1.7 9.5 49.2 13 6.7 0.0 13.5 15 2 2 17 17 15 0 Tetratricopeptide repeat TPR_6 PF13174.1 EWM28211.1 - 3.5 8.2 12.0 28 5.4 0.0 6.5 7 0 0 7 7 5 0 Tetratricopeptide repeat DUF4506 PF14958.1 EWM28212.1 - 0.0011 18.5 0.0 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4506) WD40 PF00400.27 EWM28213.1 - 9.6e-46 152.1 3.0 3.2e-09 36.2 0.0 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 EWM28213.1 - 5e-08 31.5 6.6 0.022 12.9 0.1 4.7 2 1 2 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EWM28213.1 - 0.00016 20.5 0.7 0.13 10.9 0.0 3.3 1 1 2 4 4 4 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 EWM28213.1 - 0.016 13.5 0.0 4 5.6 0.0 2.4 2 1 0 2 2 2 0 Cytochrome D1 heme domain SUKH_5 PF14567.1 EWM28213.1 - 0.022 14.1 0.0 0.99 8.8 0.0 2.6 2 0 0 2 2 2 0 SMI1-KNR4 cell-wall WD40 PF00400.27 EWM28214.1 - 1.6e-36 122.8 24.4 7.4e-07 28.8 0.7 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat DUF718 PF05336.8 EWM28215.1 - 0.076 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF718) Amidohydro_3 PF07969.6 EWM28216.1 - 8.2e-75 252.5 0.0 1.2e-74 252.0 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 EWM28216.1 - 4e-12 46.4 0.3 3e-08 33.6 0.0 2.8 2 2 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EWM28216.1 - 7.6e-07 29.4 0.1 0.035 14.1 0.0 3.5 3 1 0 3 3 3 2 Amidohydrolase Amidohydro_5 PF13594.1 EWM28216.1 - 5.4e-06 26.1 0.0 1.4e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EWM28217.1 - 7.7e-75 252.6 0.0 1.1e-74 252.1 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 EWM28217.1 - 2.4e-12 47.1 0.3 3e-08 33.7 0.0 3.0 2 2 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EWM28217.1 - 7.4e-07 29.4 0.1 0.035 14.1 0.0 3.5 3 1 0 3 3 3 2 Amidohydrolase Amidohydro_5 PF13594.1 EWM28217.1 - 5.4e-06 26.1 0.0 1.4e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase AAA_13 PF13166.1 EWM28218.1 - 0.074 11.5 1.2 0.11 10.8 0.9 1.2 1 0 0 1 1 1 0 AAA domain PAT1 PF09770.4 EWM28218.1 - 0.32 9.1 30.8 0.01 14.1 16.8 1.6 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Baculo_PEP_C PF04513.7 EWM28218.1 - 0.54 10.0 3.8 1.4 8.7 0.8 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 EWM28218.1 - 3.9 7.0 22.4 0.013 15.0 6.1 3.1 3 1 1 4 4 4 0 IncA protein IU_nuc_hydro PF01156.14 EWM28219.1 - 1.4e-78 264.2 0.1 1.7e-78 264.0 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF3574 PF12098.3 EWM28219.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3574) PPR_2 PF13041.1 EWM28220.1 - 8.3e-120 390.6 5.3 1.9e-12 46.9 0.0 16.3 7 2 10 17 17 17 16 PPR repeat family PPR_3 PF13812.1 EWM28220.1 - 3.3e-110 351.3 39.6 9.8e-09 34.8 0.0 21.7 21 0 0 21 21 21 17 Pentatricopeptide repeat domain PPR PF01535.15 EWM28220.1 - 6.5e-100 320.4 20.7 2.6e-06 27.0 0.1 21.2 21 0 0 21 21 21 17 PPR repeat PPR_1 PF12854.2 EWM28220.1 - 8e-100 325.9 15.2 4e-08 32.6 0.0 19.5 19 0 0 19 19 19 16 PPR repeat Aa_trans PF01490.13 EWM28220.1 - 1.8e-31 109.0 18.3 3e-31 108.3 12.7 1.4 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TPR_14 PF13428.1 EWM28220.1 - 7.9e-24 81.9 44.9 0.41 11.4 0.0 18.1 8 4 10 18 18 18 6 Tetratricopeptide repeat TPR_16 PF13432.1 EWM28220.1 - 7.7e-11 42.3 27.2 0.045 14.4 0.1 10.2 10 1 2 12 12 12 3 Tetratricopeptide repeat TPR_19 PF14559.1 EWM28220.1 - 2.3e-10 40.6 16.4 0.89 9.9 0.1 10.1 6 3 5 11 11 11 3 Tetratricopeptide repeat TPR_7 PF13176.1 EWM28220.1 - 3.5e-07 29.5 1.0 4.5 7.3 0.0 8.4 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_12 PF13424.1 EWM28220.1 - 8.3e-07 28.8 17.0 6.3 6.8 0.1 9.9 9 2 4 13 13 12 3 Tetratricopeptide repeat ECSIT PF06239.6 EWM28220.1 - 7.6e-06 24.9 0.0 34 3.2 0.0 7.5 5 3 2 8 8 8 0 Evolutionarily conserved signalling intermediate in Toll pathway TPR_4 PF07721.9 EWM28220.1 - 8.1e-06 25.7 21.3 0.19 12.2 0.0 10.9 11 0 0 11 11 10 1 Tetratricopeptide repeat DUF3366 PF11846.3 EWM28220.1 - 0.00013 21.8 18.8 6.8 6.5 0.2 8.8 7 3 3 10 10 10 2 Domain of unknown function (DUF3366) MRP-S27 PF10037.4 EWM28220.1 - 0.075 11.9 0.0 1.4 7.7 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 DUF2431 PF10354.4 EWM28222.1 - 1.6e-26 93.2 0.0 2.5e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) zf-C2H2 PF00096.21 EWM28222.1 - 7.4e-08 32.2 16.3 0.015 15.6 0.8 4.9 5 0 0 5 5 4 3 Zinc finger, C2H2 type zf-met PF12874.2 EWM28222.1 - 2.8e-07 30.5 3.7 0.89 9.8 0.0 4.6 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EWM28222.1 - 1.6e-06 27.7 8.9 0.0039 17.0 0.1 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EWM28222.1 - 1.3e-05 25.1 15.1 0.032 14.3 0.0 4.7 5 0 0 5 5 4 3 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EWM28222.1 - 0.00038 20.5 10.9 0.39 11.0 0.0 5.2 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EWM28222.1 - 0.00059 19.9 14.5 1 9.8 0.0 4.8 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EWM28222.1 - 0.013 15.5 8.2 2.4 8.3 0.3 3.8 2 2 1 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 EWM28222.1 - 0.089 12.9 2.9 11 6.2 0.0 3.6 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-met2 PF12907.2 EWM28222.1 - 0.09 12.7 3.8 35 4.4 0.0 3.8 3 0 0 3 3 3 0 Zinc-binding Rubredoxin PF00301.15 EWM28222.1 - 0.42 10.5 9.7 3.5 7.5 0.0 4.9 6 0 0 6 6 6 0 Rubredoxin zf-SNAP50_C PF12251.3 EWM28222.1 - 0.55 9.5 5.5 0.048 13.0 0.4 1.6 2 0 0 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal Zn-ribbon_8 PF09723.5 EWM28222.1 - 2.9 7.9 9.0 2 8.4 0.1 3.7 4 0 0 4 4 4 0 Zinc ribbon domain SF3b10 PF07189.6 EWM28223.1 - 2.3e-36 123.4 0.1 2.7e-36 123.2 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) RRM_3 PF08777.6 EWM28223.1 - 0.017 14.9 0.0 0.025 14.4 0.0 1.3 1 1 0 1 1 1 0 RNA binding motif Longin PF13774.1 EWM28223.1 - 0.08 12.5 0.0 0.099 12.2 0.0 1.2 1 0 0 1 1 1 0 Regulated-SNARE-like domain Y_phosphatase PF00102.22 EWM28224.1 - 1.5e-05 24.4 0.0 2.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EWM28224.1 - 1.6e-05 24.4 0.0 5.3e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Adaptin_binding PF10199.4 EWM28225.1 - 5.5e-05 23.4 1.3 0.00025 21.3 0.9 2.0 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 SDP_N PF12278.3 EWM28225.1 - 0.029 14.0 0.6 0.048 13.2 0.4 1.3 1 0 0 1 1 1 0 Sex determination protein N terminal adh_short PF00106.20 EWM28226.1 - 1.3e-24 87.0 0.0 1.9e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EWM28226.1 - 2.1e-10 40.5 0.0 4.5e-10 39.4 0.0 1.4 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EWM28226.1 - 3.4e-10 40.1 0.0 5e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EWM28226.1 - 9.2e-06 25.7 0.2 3e-05 24.1 0.1 2.0 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EWM28226.1 - 0.0048 16.3 0.1 0.054 12.9 0.0 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF3329 PF11808.3 EWM28226.1 - 0.029 14.4 0.6 0.097 12.7 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) Peptidase_S9 PF00326.16 EWM28227.1 - 1.2e-33 116.1 0.0 3.7e-32 111.2 0.0 2.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.10 EWM28227.1 - 8.1e-30 103.7 0.0 3.1e-29 101.8 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Abhydrolase_6 PF12697.2 EWM28227.1 - 2.8e-05 24.1 5.1 7e-05 22.8 3.5 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Solute_trans_a PF03619.11 EWM28229.1 - 1.2e-78 264.2 13.8 1.6e-78 263.8 9.6 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha RWD PF05773.17 EWM28230.1 - 5e-15 55.3 0.0 8.5e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 RWD domain Pilt PF15453.1 EWM28230.1 - 0.00053 19.7 5.4 0.00083 19.1 3.8 1.2 1 0 0 1 1 1 1 Protein incorporated later into Tight Junctions YL1 PF05764.8 EWM28230.1 - 0.34 10.4 24.8 0.032 13.8 13.5 1.8 2 0 0 2 2 2 0 YL1 nuclear protein Nop14 PF04147.7 EWM28230.1 - 0.48 8.2 18.2 0.69 7.7 12.6 1.1 1 0 0 1 1 1 0 Nop14-like family Fer2 PF00111.22 EWM28231.1 - 2.2e-14 52.9 1.4 2.9e-14 52.5 1.0 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain SP2 PF03014.9 EWM28231.1 - 0.0063 14.4 0.0 0.0079 14.1 0.0 1.2 1 0 0 1 1 1 1 Structural protein 2 APS_kinase PF01583.15 EWM28233.1 - 2.8e-63 212.2 0.0 5.1e-63 211.4 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-sulfurylase PF01747.12 EWM28233.1 - 5.1e-54 182.8 0.0 1.6e-53 181.2 0.0 1.9 2 1 0 2 2 2 1 ATP-sulfurylase Pyrophosphatase PF00719.14 EWM28233.1 - 7.5e-39 132.6 0.0 1.2e-38 132.0 0.0 1.3 1 0 0 1 1 1 1 Inorganic pyrophosphatase PUA_2 PF14306.1 EWM28233.1 - 7.3e-34 116.4 0.0 1.8e-32 111.9 0.0 3.0 3 0 0 3 3 3 1 PUA-like domain AAA_33 PF13671.1 EWM28233.1 - 3.9e-07 30.0 0.0 8.5e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EWM28233.1 - 6.9e-06 26.8 0.2 3.4e-05 24.6 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EWM28233.1 - 0.00015 22.0 0.0 0.00036 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EWM28233.1 - 0.0015 17.6 0.0 0.003 16.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.1 EWM28233.1 - 0.0077 15.7 0.0 0.024 14.1 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EWM28233.1 - 0.0088 16.3 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter KTI12 PF08433.5 EWM28233.1 - 0.02 14.1 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_16 PF13191.1 EWM28233.1 - 0.096 12.6 0.1 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 EWM28233.1 - 0.16 12.1 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase HMG_box PF00505.14 EWM28234.1 - 3.3e-18 65.6 2.6 3.3e-18 65.6 1.8 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EWM28234.1 - 1.6e-13 50.7 1.3 1.6e-13 50.7 0.9 2.3 2 0 0 2 2 2 1 HMG-box domain DUF1014 PF06244.7 EWM28234.1 - 0.043 14.0 0.3 0.043 14.0 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1014) DUF3602 PF12223.3 EWM28234.1 - 2.8 8.3 8.9 22 5.5 6.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3602) DUF2201_N PF13203.1 EWM28234.1 - 6.8 5.7 11.1 11 5.0 7.7 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.9 EWM28234.1 - 9.7 4.0 14.1 12 3.7 9.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Cyclin_N PF00134.18 EWM28235.1 - 1.9e-18 66.2 0.0 3.5e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EWM28235.1 - 8.8e-08 32.0 0.1 2.2e-07 30.7 0.1 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain RRM_1 PF00076.17 EWM28236.1 - 4.6e-15 54.9 0.0 1.2e-06 28.0 0.0 4.8 5 0 0 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM28236.1 - 7e-12 45.1 0.0 2.2e-05 24.3 0.0 4.5 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S5 PF00333.15 EWM28236.1 - 1e-11 44.3 0.1 2.2e-11 43.2 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EWM28236.1 - 3.4e-05 23.0 0.0 7.7e-05 21.8 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain SET PF00856.23 EWM28237.1 - 7.5e-07 29.5 0.0 0.012 15.9 0.0 2.2 2 0 0 2 2 2 2 SET domain GT36_AF PF06205.6 EWM28237.1 - 0.095 12.4 0.0 0.64 9.8 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase 36 associated family tRNA_bind PF01588.15 EWM28239.1 - 2.9e-29 100.7 0.0 5.5e-29 99.8 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain fn3 PF00041.16 EWM28239.1 - 9.7e-08 32.0 0.0 2e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain DUF87 PF01935.12 EWM28240.1 - 0.17 11.6 0.8 2.1 8.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 Muted PF14942.1 EWM28240.1 - 0.37 10.6 6.0 0.47 10.3 0.4 2.3 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Syntaxin PF00804.20 EWM28240.1 - 2 8.6 6.7 1.8 8.7 0.9 2.7 1 1 1 2 2 2 0 Syntaxin WXG100 PF06013.7 EWM28240.1 - 2.9 7.9 8.4 2.7 8.0 0.1 3.2 3 0 0 3 3 3 0 Proteins of 100 residues with WXG ING PF12998.2 EWM28240.1 - 4.7 7.5 6.3 3 8.1 1.5 2.7 2 2 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Muted PF14942.1 EWM28241.1 - 0.14 12.0 6.0 0.26 11.1 0.4 2.2 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein WXG100 PF06013.7 EWM28241.1 - 0.64 10.0 8.1 1.6 8.8 0.1 3.1 3 0 0 3 3 3 0 Proteins of 100 residues with WXG ING PF12998.2 EWM28241.1 - 0.78 10.0 4.1 1.9 8.8 1.6 2.5 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Syntaxin PF00804.20 EWM28241.1 - 2.1 8.5 6.6 3.5 7.8 1.1 2.7 1 1 1 2 2 2 0 Syntaxin GAT PF03127.9 EWM28241.1 - 3.8 7.5 6.1 2.8 7.9 0.4 2.6 3 0 0 3 3 3 0 GAT domain IFT57 PF10498.4 EWM28242.1 - 8.7e-09 34.5 7.6 6.9e-08 31.6 2.7 2.6 1 1 0 2 2 2 2 Intra-flagellar transport protein 57 DUF3223 PF11523.3 EWM28242.1 - 0.077 13.2 0.0 0.23 11.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3223) Fib_alpha PF08702.5 EWM28242.1 - 0.082 13.0 10.8 0.2 11.8 7.5 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Rieske PF00355.21 EWM28243.1 - 5e-18 64.4 0.5 9e-18 63.6 0.1 1.6 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain CytB6-F_Fe-S PF08802.5 EWM28243.1 - 2.2e-13 49.9 1.1 2.2e-13 49.9 0.8 1.8 2 0 0 2 2 2 1 Cytochrome B6-F complex Fe-S subunit Cyt-b5 PF00173.23 EWM28245.1 - 5.3e-18 64.6 0.0 1.1e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TUSC2 PF15000.1 EWM28245.1 - 0.058 13.4 0.1 0.096 12.7 0.0 1.3 1 0 0 1 1 1 0 Tumour suppressor candidate 2 PWWP PF00855.12 EWM28247.1 - 2.7e-11 43.5 0.5 2.7e-11 43.5 0.4 2.2 2 0 0 2 2 2 1 PWWP domain Med26 PF08711.6 EWM28247.1 - 2.5e-09 36.4 0.0 2.5e-09 36.4 0.0 1.8 2 0 0 2 2 2 1 TFIIS helical bundle-like domain LEDGF PF11467.3 EWM28247.1 - 0.0023 17.5 0.1 0.0058 16.3 0.1 1.6 1 0 0 1 1 1 1 Lens epithelium-derived growth factor (LEDGF) Sec7 PF01369.15 EWM28249.1 - 6.7e-45 153.0 0.0 1.1e-44 152.4 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EWM28249.1 - 2.5e-16 59.5 0.1 1.9e-15 56.7 0.0 2.1 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal PH PF00169.24 EWM28249.1 - 1.7e-07 31.3 0.1 3.7e-07 30.3 0.1 1.6 1 0 0 1 1 1 1 PH domain ACBP PF00887.14 EWM28249.1 - 0.008 15.8 0.0 0.022 14.4 0.0 1.7 1 0 0 1 1 1 1 Acyl CoA binding protein DUF2464 PF10240.4 EWM28249.1 - 0.051 12.9 0.0 9.2 5.5 0.0 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF2464) COPIIcoated_ERV PF07970.7 EWM28250.1 - 1.2e-62 211.4 0.0 1.7e-62 210.9 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EWM28250.1 - 4.6e-24 84.2 0.0 9e-24 83.2 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Methyltransf_32 PF13679.1 EWM28251.1 - 1.5e-36 125.1 0.1 7.7e-35 119.6 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM28251.1 - 8.3e-16 57.9 0.0 1.5e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM28251.1 - 1.3e-10 41.8 0.0 2.6e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM28251.1 - 2.2e-07 30.9 0.2 5.3e-07 29.6 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM28251.1 - 8.3e-07 29.3 0.1 2.1e-06 28.0 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain TRM13 PF05206.9 EWM28251.1 - 0.00027 20.2 0.0 0.6 9.2 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase TRM13 Methyltransf_11 PF08241.7 EWM28251.1 - 0.00087 19.7 0.0 0.0026 18.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EWM28251.1 - 0.0018 17.8 0.0 0.0034 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 EWM28251.1 - 0.0039 16.9 0.0 0.0074 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Head-tail_con PF12236.3 EWM28251.1 - 0.022 13.1 0.0 0.033 12.5 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage head to tail connecting protein Methyltransf_12 PF08242.7 EWM28251.1 - 0.036 14.5 0.0 0.12 12.8 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain LNS2 PF08235.8 EWM28252.1 - 1.1e-35 122.4 0.0 1.6e-35 121.9 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) DMRL_synthase PF00885.14 EWM28253.1 - 1.7e-49 167.1 0.1 2.4e-49 166.7 0.0 1.2 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase TMEM164 PF14808.1 EWM28255.1 - 1.7e-21 76.5 7.3 2.2e-21 76.2 5.0 1.0 1 0 0 1 1 1 1 TMEM164 family SBF PF01758.11 EWM28256.1 - 1.3e-34 119.2 14.4 1.3e-34 119.2 9.9 1.8 2 1 0 2 2 2 1 Sodium Bile acid symporter family Adap_comp_sub PF00928.16 EWM28257.1 - 2.9e-68 229.8 0.0 3.7e-68 229.4 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EWM28257.1 - 0.002 17.8 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain WD40 PF00400.27 EWM28258.1 - 9.9e-21 72.8 3.1 3.6e-07 29.7 0.3 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat AA_kinase PF00696.23 EWM28259.1 - 9.4e-50 169.4 0.0 1.7e-49 168.5 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 EWM28259.1 - 1.7e-07 30.5 3.3 0.003 17.0 0.1 3.1 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.1 EWM28259.1 - 6.2e-07 28.8 1.7 6.2e-05 22.4 0.4 2.7 2 0 0 2 2 2 2 ACT domain DUF2007 PF09413.5 EWM28259.1 - 0.0036 17.1 0.1 0.016 15.0 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF2007) DUF4611 PF15387.1 EWM28259.1 - 0.12 12.5 0.2 3.9 7.6 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) ECH_C PF13766.1 EWM28260.1 - 2.8e-17 62.9 0.1 5.8e-17 61.9 0.1 1.5 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EWM28260.1 - 1.7e-07 30.6 0.0 3e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family SDA1 PF05285.7 EWM28260.1 - 0.63 9.2 7.6 0.91 8.7 5.3 1.2 1 0 0 1 1 1 0 SDA1 DUF2937 PF11157.3 EWM28261.1 - 0.14 11.4 0.7 0.25 10.6 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Brix PF04427.13 EWM28262.1 - 7.4e-46 156.2 0.0 1.1e-45 155.6 0.0 1.3 1 0 0 1 1 1 1 Brix domain Bromodomain PF00439.20 EWM28262.1 - 0.0059 16.5 0.0 0.011 15.6 0.0 1.6 1 1 0 1 1 1 1 Bromodomain Orn_Arg_deC_N PF02784.11 EWM28263.1 - 7.2e-74 248.1 0.0 9.4e-74 247.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EWM28263.1 - 1.3e-28 99.0 0.0 2.9e-28 97.9 0.0 1.6 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Peptidase_M24 PF00557.19 EWM28264.1 - 1.3e-45 155.5 0.0 2.6e-45 154.5 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Macoilin PF09726.4 EWM28264.1 - 0.12 10.6 2.5 0.17 10.1 1.7 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF4604 PF15377.1 EWM28264.1 - 1.6 8.9 19.8 3.9 7.6 13.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) NST1 PF13945.1 EWM28264.1 - 6.6 6.7 16.6 3.8 7.5 4.4 2.3 1 1 1 2 2 2 0 Salt tolerance down-regulator Nitroreductase PF00881.19 EWM28266.1 - 2.6e-23 82.6 0.2 4.9e-23 81.7 0.1 1.5 1 1 0 1 1 1 1 Nitroreductase family MMR_HSR1 PF01926.18 EWM28267.1 - 5e-53 177.9 0.4 3.3e-27 94.7 0.1 2.6 3 0 0 3 3 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.1 EWM28267.1 - 2.3e-30 104.3 0.0 3.9e-30 103.6 0.0 1.4 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.13 EWM28267.1 - 6.6e-22 77.4 0.3 5.1e-13 48.5 0.1 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.22 EWM28267.1 - 5e-20 71.7 0.7 1.2e-09 37.8 0.3 4.7 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain Miro PF08477.8 EWM28267.1 - 1.4e-16 61.0 0.0 1.7e-08 34.9 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AIG1 PF04548.11 EWM28267.1 - 2.6e-12 46.3 0.0 1.4e-05 24.2 0.0 2.8 3 0 0 3 3 3 2 AIG1 family Dynamin_N PF00350.18 EWM28267.1 - 7.8e-10 38.8 0.0 0.012 15.4 0.0 4.6 5 0 0 5 5 5 2 Dynamin family AAA_17 PF13207.1 EWM28267.1 - 6.6e-08 33.4 0.4 0.00076 20.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain Ras PF00071.17 EWM28267.1 - 4.1e-07 29.5 0.3 0.00012 21.5 0.1 2.8 2 1 0 2 2 2 1 Ras family ABC_tran PF00005.22 EWM28267.1 - 1e-06 29.0 0.0 0.031 14.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter DUF258 PF03193.11 EWM28267.1 - 1.2e-06 27.7 0.0 0.0091 15.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 EWM28267.1 - 1.4e-06 28.6 0.0 0.045 14.0 0.0 2.8 2 1 0 2 2 2 2 AAA domain MobB PF03205.9 EWM28267.1 - 1.2e-05 25.0 0.1 0.19 11.4 0.0 3.4 4 0 0 4 4 4 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EWM28267.1 - 4.2e-05 23.6 0.0 0.2 11.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain cobW PF02492.14 EWM28267.1 - 0.00018 21.0 1.5 0.1 12.0 0.3 3.6 2 1 2 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EWM28267.1 - 0.00021 20.1 2.9 1.5 7.4 0.0 3.4 3 0 0 3 3 3 1 ArgK protein Arch_ATPase PF01637.13 EWM28267.1 - 0.00023 20.9 0.7 0.083 12.5 0.3 2.7 2 1 0 2 2 2 1 Archaeal ATPase Guanylate_kin PF00625.16 EWM28267.1 - 0.00031 20.2 0.0 0.032 13.6 0.0 2.4 2 0 0 2 2 2 1 Guanylate kinase AAA_25 PF13481.1 EWM28267.1 - 0.00037 19.9 0.3 0.069 12.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 EWM28267.1 - 0.0007 19.7 0.0 0.26 11.4 0.0 3.0 3 0 0 3 3 3 1 RNA helicase FtsK_SpoIIIE PF01580.13 EWM28267.1 - 0.0015 18.0 0.4 1.8 7.9 0.0 3.1 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_14 PF13173.1 EWM28267.1 - 0.0024 17.7 0.0 1.5 8.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 EWM28267.1 - 0.0057 16.3 0.0 0.88 9.2 0.0 2.6 2 0 0 2 2 2 1 NTPase Arf PF00025.16 EWM28267.1 - 0.01 15.1 0.2 1.6 7.9 0.1 3.2 2 1 0 2 2 2 0 ADP-ribosylation factor family AAA_10 PF12846.2 EWM28267.1 - 0.017 14.5 0.0 2 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain PduV-EutP PF10662.4 EWM28267.1 - 0.022 14.2 0.2 14 5.1 0.0 3.6 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 EWM28267.1 - 0.029 14.3 0.0 4.7 7.1 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 EWM28267.1 - 0.03 14.3 0.0 4.2 7.3 0.0 2.8 2 1 0 2 2 2 0 AAA domain GBP PF02263.14 EWM28267.1 - 0.032 13.2 0.0 0.82 8.6 0.0 2.4 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain Septin PF00735.13 EWM28267.1 - 0.044 12.7 0.0 2.9 6.8 0.0 2.2 2 0 0 2 2 2 0 Septin SRPRB PF09439.5 EWM28267.1 - 0.066 12.4 0.0 1.1 8.4 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.1 EWM28267.1 - 0.069 12.6 0.0 12 5.4 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_33 PF13671.1 EWM28267.1 - 0.09 12.6 0.0 16 5.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain KTI12 PF08433.5 EWM28267.1 - 0.12 11.5 0.0 1.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA PF00004.24 EWM28267.1 - 0.13 12.5 0.0 6.9 6.8 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 EWM28267.1 - 0.14 11.7 0.0 0.83 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EWM28268.1 - 1.1e-28 100.1 0.0 1.9e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EWM28268.1 - 5.3e-05 23.1 0.0 0.00015 21.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EWM28268.1 - 0.0092 15.1 0.8 0.15 11.1 0.0 2.4 2 0 0 2 2 2 1 AIG1 family DUF258 PF03193.11 EWM28268.1 - 0.022 13.9 0.0 7.4 5.7 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function, DUF258 Miro PF08477.8 EWM28268.1 - 0.07 13.6 0.0 0.22 12.0 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 EWM28268.1 - 0.18 11.3 0.1 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain Aa_trans PF01490.13 EWM28269.1 - 1.2e-05 23.9 8.2 0.00011 20.8 1.6 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EWM28269.1 - 0.0097 14.7 0.5 0.0097 14.7 0.4 2.1 2 0 0 2 2 2 2 Tryptophan/tyrosine permease family PNP_UDP_1 PF01048.15 EWM28270.1 - 1.3e-26 93.0 0.0 2.4e-26 92.1 0.0 1.5 1 1 0 1 1 1 1 Phosphorylase superfamily Arginosuc_synth PF00764.14 EWM28271.1 - 1.8e-153 511.2 0.0 2e-153 511.0 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 EWM28271.1 - 0.024 13.8 0.0 0.049 12.8 0.0 1.5 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC DUF4427 PF14468.1 EWM28271.1 - 0.12 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4427) PDZ PF00595.19 EWM28272.1 - 9.5e-05 22.5 0.1 0.00027 21.0 0.1 1.8 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) MPLKIP PF15502.1 EWM28273.1 - 8.4e-07 29.8 7.6 1.2e-06 29.3 4.9 1.6 1 1 0 1 1 1 1 M-phase-specific PLK1-interacting protein APH PF01636.18 EWM28274.1 - 2.4e-22 79.8 0.0 3.5e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EWM28274.1 - 2.5e-09 37.0 0.6 2.3e-07 30.5 0.2 2.3 2 0 0 2 2 2 2 Choline/ethanolamine kinase EcKinase PF02958.15 EWM28274.1 - 0.002 17.2 0.1 0.0036 16.4 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase PF00069.20 EWM28274.1 - 0.082 12.0 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Methyltransf_23 PF13489.1 EWM28276.1 - 6.8e-16 58.4 0.0 8.4e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM28276.1 - 1.7e-15 57.2 0.0 2.5e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM28276.1 - 1.8e-14 53.9 0.0 2.5e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM28276.1 - 1.9e-12 47.0 0.0 2.5e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EWM28276.1 - 3.8e-12 45.8 0.0 5.2e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EWM28276.1 - 7.5e-11 42.6 0.0 1.2e-10 41.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM28276.1 - 5.7e-08 32.8 0.1 1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM28276.1 - 7.3e-07 29.4 0.0 1.1e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EWM28276.1 - 0.00017 20.9 0.0 0.00037 19.7 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase PCMT PF01135.14 EWM28276.1 - 0.00091 18.8 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.10 EWM28276.1 - 0.0023 17.6 0.1 0.008 15.8 0.0 1.8 2 1 0 2 2 2 1 Hypothetical methyltransferase NNMT_PNMT_TEMT PF01234.12 EWM28276.1 - 0.021 13.8 0.0 0.099 11.5 0.0 1.8 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family DUF938 PF06080.7 EWM28276.1 - 0.07 12.6 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_24 PF13578.1 EWM28276.1 - 0.074 13.8 0.0 0.14 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_L20 PF00453.13 EWM28277.1 - 3.2e-41 139.5 2.6 4.3e-41 139.2 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L20 Radical_SAM PF04055.16 EWM28279.1 - 1.1e-34 120.0 0.0 2.6e-34 118.8 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily UPF0004 PF00919.15 EWM28279.1 - 1.2e-18 66.6 0.0 2.8e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.15 EWM28279.1 - 1.3e-06 28.1 0.0 3.1e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 TRAM domain Fer4_12 PF13353.1 EWM28279.1 - 0.073 13.1 0.1 0.46 10.5 0.0 2.1 2 0 0 2 2 2 0 4Fe-4S single cluster domain FPN1 PF06963.7 EWM28280.1 - 2e-91 306.5 17.9 2.7e-91 306.1 12.4 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) DAHP_synth_2 PF01474.11 EWM28282.1 - 2.2e-129 431.6 0.0 2.4e-129 431.5 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Cyt-b5 PF00173.23 EWM28282.1 - 0.13 12.0 0.1 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain Xan_ur_permease PF00860.15 EWM28284.1 - 4.6e-27 94.5 38.8 5.4e-27 94.2 26.9 1.1 1 0 0 1 1 1 1 Permease family Aa_trans PF01490.13 EWM28285.1 - 2e-30 105.6 0.0 4.4e-30 104.4 0.0 1.5 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Use1 PF09753.4 EWM28286.1 - 4.3e-17 62.3 1.0 1.8e-16 60.3 0.7 1.8 1 1 0 1 1 1 1 Membrane fusion protein Use1 KLRAQ PF10205.4 EWM28286.1 - 0.0031 17.5 6.0 0.013 15.5 0.7 2.8 3 0 0 3 3 3 1 Predicted coiled-coil domain-containing protein DUF4407 PF14362.1 EWM28286.1 - 0.037 12.9 0.3 0.055 12.4 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) VIT1 PF01988.14 EWM28286.1 - 0.16 11.4 0.1 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 VIT family Lectin_N PF03954.9 EWM28286.1 - 1.7 8.0 5.6 0.98 8.8 1.9 1.9 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain SNARE PF05739.14 EWM28286.1 - 2.2 8.0 6.4 0.65 9.7 1.4 2.3 3 0 0 3 3 3 0 SNARE domain Fer2 PF00111.22 EWM28287.1 - 2.3e-09 36.8 4.0 3.5e-09 36.2 2.8 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Zn_Tnp_IS91 PF14319.1 EWM28287.1 - 0.1 12.1 2.0 0.13 11.7 0.8 1.6 1 1 0 1 1 1 0 Transposase zinc-binding domain Tim44 PF04280.10 EWM28288.1 - 0.0036 17.2 0.3 0.0088 16.0 0.1 1.7 2 0 0 2 2 2 1 Tim44-like domain Actin PF00022.14 EWM28289.1 - 2.3e-128 428.0 0.0 2.5e-128 427.8 0.0 1.0 1 0 0 1 1 1 1 Actin PseudoU_synth_2 PF00849.17 EWM28290.1 - 3.5e-26 91.9 0.3 3e-24 85.6 0.2 2.2 2 0 0 2 2 2 2 RNA pseudouridylate synthase GEMIN8 PF15348.1 EWM28290.1 - 0.023 14.7 0.3 0.038 14.0 0.2 1.3 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 THUMP PF02926.12 EWM28292.1 - 3.2e-06 27.0 0.0 5.8e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 THUMP domain LysR_substrate PF03466.15 EWM28292.1 - 0.066 12.3 0.0 0.097 11.7 0.0 1.2 1 0 0 1 1 1 0 LysR substrate binding domain Ribosomal_L6e PF01159.14 EWM28294.1 - 0.15 12.2 7.8 0.38 11.0 5.4 1.6 1 0 0 1 1 1 0 Ribosomal protein L6e Ycf1 PF05758.7 EWM28294.1 - 4.4 4.8 9.1 6.2 4.4 6.3 1.1 1 0 0 1 1 1 0 Ycf1 Phage_int_SAM_1 PF02899.12 EWM28295.1 - 0.00023 21.2 1.0 0.0041 17.2 0.1 3.1 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.1 EWM28295.1 - 0.026 14.8 1.1 4.9 7.5 0.1 2.9 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_1 PF02899.12 EWM28296.1 - 0.00023 21.2 1.0 0.0041 17.2 0.1 3.1 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.1 EWM28296.1 - 0.026 14.8 1.1 4.9 7.5 0.1 2.9 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain HEAT_2 PF13646.1 EWM28298.1 - 4.1e-11 42.9 4.6 0.00031 20.9 0.1 5.6 4 2 1 5 5 5 3 HEAT repeats HEAT PF02985.17 EWM28298.1 - 1.6e-10 40.1 10.1 0.0095 15.9 0.0 7.6 7 0 0 7 7 7 3 HEAT repeat CLASP_N PF12348.3 EWM28298.1 - 4.1e-05 23.0 0.0 0.014 14.7 0.0 3.2 3 0 0 3 3 3 1 CLASP N terminal Ecm29 PF13001.2 EWM28298.1 - 0.00051 18.6 0.0 0.00085 17.9 0.0 1.3 1 0 0 1 1 1 1 Proteasome stabiliser HEAT_EZ PF13513.1 EWM28298.1 - 0.0013 19.1 13.2 1.8 9.1 0.0 6.1 7 0 0 7 7 7 2 HEAT-like repeat ACDC PF14733.1 EWM28298.1 - 0.13 12.4 0.0 47 4.1 0.0 3.1 2 1 1 3 3 3 0 AP2-coincident C-terminal TPPII PF12580.3 EWM28299.1 - 8.3e-48 162.2 0.0 1.2e-47 161.7 0.0 1.2 1 0 0 1 1 1 1 Tripeptidyl peptidase II Bystin PF05291.6 EWM28300.1 - 3.2e-122 407.2 0.0 4.5e-122 406.7 0.0 1.1 1 0 0 1 1 1 1 Bystin ubiquitin PF00240.18 EWM28302.1 - 3.2e-18 64.8 0.0 5.9e-18 64.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EWM28302.1 - 1.3e-06 27.9 0.0 1.3e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EWM28302.1 - 0.00015 21.8 0.0 0.00095 19.3 0.0 2.4 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EWM28302.1 - 0.083 12.7 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EWM28303.1 - 3.6e-18 64.7 0.0 6.5e-18 63.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EWM28303.1 - 1.4e-06 27.8 1.2 1.5e-06 27.8 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EWM28303.1 - 0.00018 21.6 0.0 0.0011 19.1 0.0 2.3 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EWM28303.1 - 0.093 12.6 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like ELO PF01151.13 EWM28304.1 - 3.4e-66 223.0 11.3 4.4e-66 222.7 7.9 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family TPR_11 PF13414.1 EWM28305.1 - 3.4e-26 90.6 10.3 2.6e-10 39.7 0.1 4.3 2 2 1 4 4 4 4 TPR repeat TPR_2 PF07719.12 EWM28305.1 - 3.9e-20 70.1 13.9 2.4e-05 23.8 0.1 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.23 EWM28305.1 - 1.8e-19 68.4 11.0 3e-06 26.5 0.1 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 EWM28305.1 - 3.5e-13 49.8 23.9 7.3e-07 29.7 0.6 5.9 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 EWM28305.1 - 3.6e-11 42.3 3.5 1 9.7 0.0 5.8 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 EWM28305.1 - 4e-10 39.4 8.4 9.1e-06 25.5 0.9 4.1 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 EWM28305.1 - 4e-09 35.6 5.0 0.05 13.3 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 EWM28305.1 - 1.3e-08 33.9 5.6 0.065 13.0 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 EWM28305.1 - 1.4e-06 28.0 16.4 0.0019 18.0 0.0 5.6 4 1 3 7 7 6 4 Tetratricopeptide repeat TPR_6 PF13174.1 EWM28305.1 - 3.5e-06 27.0 14.0 0.24 11.9 0.2 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 EWM28305.1 - 0.00025 21.4 26.0 0.98 10.2 0.0 7.2 4 2 4 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 EWM28305.1 - 0.0012 19.1 1.8 0.0012 19.1 1.2 4.1 2 1 3 5 5 4 1 Tetratricopeptide repeat TPR_4 PF07721.9 EWM28305.1 - 0.051 14.0 6.1 12 6.6 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3856 PF12968.2 EWM28305.1 - 0.054 13.3 1.1 0.37 10.6 0.4 2.7 2 1 0 2 2 2 0 Domain of Unknown Function (DUF3856) BTAD PF03704.12 EWM28305.1 - 0.062 13.5 0.1 0.062 13.5 0.1 2.9 2 1 0 3 3 2 0 Bacterial transcriptional activator domain TPR_10 PF13374.1 EWM28305.1 - 0.7 9.9 13.6 0.18 11.7 0.3 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat Thioredoxin PF00085.15 EWM28306.1 - 3.1e-20 71.7 0.0 3.9e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EWM28306.1 - 1e-06 28.8 0.0 2.3e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EWM28306.1 - 0.0012 18.5 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 EWM28306.1 - 0.0027 17.7 0.0 0.0039 17.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EWM28306.1 - 0.0028 17.2 0.0 0.0032 17.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 EWM28306.1 - 0.0081 15.7 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin Glutaredoxin PF00462.19 EWM28306.1 - 0.017 15.0 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin Thioredoxin_7 PF13899.1 EWM28306.1 - 0.047 13.7 0.0 0.09 12.8 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like GARS_A PF01071.14 EWM28309.1 - 2.7e-65 219.5 0.0 4e-65 219.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Formyl_trans_N PF00551.14 EWM28309.1 - 7.2e-33 113.6 0.0 1.7e-32 112.4 0.0 1.7 2 0 0 2 2 2 1 Formyl transferase GARS_N PF02844.10 EWM28309.1 - 9e-32 109.5 0.0 2.1e-31 108.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.11 EWM28309.1 - 2.2e-15 56.6 0.2 8.8e-15 54.6 0.0 2.2 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp_4 PF13535.1 EWM28309.1 - 1.3e-14 54.3 0.1 8.1e-14 51.7 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EWM28309.1 - 5.5e-07 29.0 0.1 2.1e-06 27.2 0.1 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.1 EWM28309.1 - 9.1e-07 27.9 0.0 3.9e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EWM28309.1 - 0.00012 21.5 0.0 0.00021 20.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EWM28309.1 - 0.009 15.8 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EWM28309.1 - 0.014 14.8 0.0 0.046 13.1 0.0 1.8 2 0 0 2 2 2 0 RimK-like ATP-grasp domain ATP-grasp_2 PF08442.5 EWM28309.1 - 0.015 14.6 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EWM28309.1 - 0.16 11.3 0.0 0.33 10.2 0.0 1.5 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Cpn10 PF00166.16 EWM28310.1 - 6.2e-27 93.3 0.0 7.9e-27 93.0 0.0 1.1 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Prp31_C PF09785.4 EWM28311.1 - 6.3e-07 29.8 0.1 9.4e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Prp31 C terminal domain Prp31_C PF09785.4 EWM28312.1 - 4e-11 43.4 7.1 4e-11 43.4 4.9 1.5 2 0 0 2 2 2 1 Prp31 C terminal domain Nop PF01798.13 EWM28312.1 - 7e-11 41.6 0.0 1.1e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain RRM_1 PF00076.17 EWM28316.1 - 4.3e-17 61.5 0.0 7.1e-17 60.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM28316.1 - 2.5e-11 43.3 0.0 4.6e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM28316.1 - 6.8e-10 38.6 0.0 1.1e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S7 PF00177.16 EWM28318.1 - 1.8e-39 134.6 2.1 2.2e-39 134.4 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF1223 PF06764.6 EWM28318.1 - 0.12 12.1 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) FolB PF02152.13 EWM28318.1 - 0.14 12.3 0.4 3 8.0 0.0 2.7 3 0 0 3 3 3 0 Dihydroneopterin aldolase PhyH PF05721.8 EWM28319.1 - 0.00011 22.2 0.0 0.0018 18.3 0.0 2.3 2 1 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.1 EWM28319.1 - 0.14 12.6 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily FAD_binding_3 PF01494.14 EWM28320.1 - 4.5e-17 62.1 0.0 9.5e-10 38.0 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EWM28320.1 - 4.9e-05 22.3 0.0 8.2e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EWM28320.1 - 5e-05 22.3 0.0 0.0001 21.2 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EWM28320.1 - 6.1e-05 22.9 0.1 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EWM28320.1 - 0.002 18.0 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EWM28320.1 - 0.0031 16.6 0.1 0.0044 16.1 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EWM28320.1 - 0.0076 15.3 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EWM28320.1 - 0.0098 14.3 0.0 0.016 13.7 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EWM28320.1 - 0.012 15.6 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EWM28320.1 - 0.05 12.2 0.0 0.068 11.7 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.17 EWM28320.1 - 0.068 12.0 0.1 0.098 11.4 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.22 EWM28320.1 - 0.11 12.9 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EWM28320.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding IGPS PF00218.16 EWM28323.1 - 9.9e-15 54.2 0.0 1.7e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase ABC_membrane PF00664.18 EWM28324.1 - 1.3e-34 119.9 0.0 1.8e-34 119.4 0.0 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region MMR_HSR1 PF01926.18 EWM28325.1 - 1.3e-38 131.4 0.0 2.8e-18 65.9 0.9 3.3 3 2 0 3 3 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.1 EWM28325.1 - 1.3e-21 76.3 0.1 2.5e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal GTP_EFTU PF00009.22 EWM28325.1 - 3.8e-16 59.0 0.0 3.1e-08 33.2 0.0 4.5 3 1 0 3 3 3 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EWM28325.1 - 5.3e-16 58.2 0.1 1.5e-07 30.8 0.0 3.7 3 0 0 3 3 3 3 Ferrous iron transport protein B Dynamin_N PF00350.18 EWM28325.1 - 2.1e-09 37.3 0.3 0.088 12.6 0.0 5.1 4 1 0 4 4 4 3 Dynamin family Miro PF08477.8 EWM28325.1 - 1.6e-06 28.5 0.1 0.08 13.4 0.0 4.2 2 2 0 2 2 2 1 Miro-like protein Arf PF00025.16 EWM28325.1 - 3.9e-05 22.9 0.0 0.22 10.7 0.0 3.8 3 0 0 3 3 3 1 ADP-ribosylation factor family AAA_16 PF13191.1 EWM28325.1 - 8.8e-05 22.5 0.3 0.067 13.1 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EWM28325.1 - 0.00018 20.7 0.0 0.27 10.4 0.0 2.7 2 1 0 2 2 2 2 Protein of unknown function, DUF258 ArgK PF03308.11 EWM28325.1 - 0.00027 19.8 3.3 1.3 7.7 0.1 4.6 5 0 0 5 5 5 1 ArgK protein ABC_tran PF00005.22 EWM28325.1 - 0.0006 20.1 0.4 0.19 11.9 0.0 3.0 3 1 0 3 3 3 1 ABC transporter cobW PF02492.14 EWM28325.1 - 0.00094 18.6 0.3 0.21 10.9 0.0 3.8 4 0 0 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EWM28325.1 - 0.001 18.7 0.0 1 9.0 0.1 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EWM28325.1 - 0.0016 19.2 0.1 1.4 9.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 EWM28325.1 - 0.0035 17.6 1.0 3.3 8.0 0.0 3.7 3 2 0 3 3 3 1 AAA domain Ras PF00071.17 EWM28325.1 - 0.0053 16.1 0.0 6.1 6.2 0.0 3.8 4 1 0 4 4 4 1 Ras family AAA_29 PF13555.1 EWM28325.1 - 0.015 14.7 0.0 4.7 6.8 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EWM28325.1 - 0.066 13.3 0.5 14 5.8 0.2 3.7 2 2 0 2 2 2 0 AAA domain GBP PF02263.14 EWM28325.1 - 0.13 11.2 0.0 6.9 5.6 0.0 2.4 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain PduV-EutP PF10662.4 EWM28325.1 - 0.16 11.4 0.0 21 4.5 0.0 3.3 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 EWM28325.1 - 4.2 7.2 13.0 0.41 10.5 0.9 3.7 4 1 0 4 4 2 0 AAA domain Pyrid_oxidase_2 PF13883.1 EWM28326.1 - 4.8e-16 58.9 0.0 1.1e-15 57.7 0.0 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF2470 PF10615.4 EWM28326.1 - 1.3e-15 57.3 0.1 2.6e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Pyridox_oxidase PF01243.15 EWM28326.1 - 1.6e-07 31.2 0.0 3.7e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase UBX PF00789.15 EWM28327.1 - 3.5e-13 49.4 0.0 6.7e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 EWM28327.1 - 4.6e-10 38.8 0.0 8.4e-10 38.0 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Spore_coat_CotO PF14153.1 EWM28327.1 - 0.33 10.3 6.1 0.6 9.5 4.2 1.4 1 0 0 1 1 1 0 Spore coat protein CotO PBP_sp32 PF07222.7 EWM28327.1 - 1.9 7.6 8.3 1.4 8.0 3.6 2.0 2 0 0 2 2 2 0 Proacrosin binding protein sp32 Borrelia_P83 PF05262.6 EWM28327.1 - 3.9 5.6 9.0 5.4 5.1 6.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF1311 PF07007.7 EWM28327.1 - 7.3 6.7 18.8 1.3 9.2 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1311) CCDC92 PF14916.1 EWM28328.1 - 0.67 9.5 2.8 0.57 9.8 0.9 1.6 2 0 0 2 2 2 0 Coiled-coil domain of unknown function SLA_LP_auto_ag PF05889.8 EWM28329.1 - 7.6e-104 347.2 0.0 5.9e-42 143.5 0.0 3.4 3 1 0 3 3 3 3 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) DUF2002 PF09400.5 EWM28329.1 - 0.01 15.5 0.0 0.042 13.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2002) SinI PF08671.5 EWM28329.1 - 0.062 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Anti-repressor SinI RAP1 PF07218.6 EWM28329.1 - 0.43 8.6 2.0 0.69 7.9 1.4 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) HgmA PF04209.8 EWM28330.1 - 2.3e-178 592.9 0.0 2.7e-178 592.6 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase HgmA PF04209.8 EWM28331.1 - 5.6e-109 364.3 0.0 7.3e-109 363.9 0.0 1.1 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase MtN3_slv PF03083.11 EWM28332.1 - 4.1e-25 87.4 9.5 1.1e-15 57.1 1.5 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Rnf-Nqr PF02508.9 EWM28332.1 - 0.18 11.3 5.2 1.7 8.2 3.6 2.0 1 1 0 1 1 1 0 Rnf-Nqr subunit, membrane protein MtN3_slv PF03083.11 EWM28333.1 - 4e-24 84.2 8.0 1.1e-15 57.2 1.5 2.4 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Rnf-Nqr PF02508.9 EWM28333.1 - 0.37 10.3 5.4 2.3 7.7 3.7 1.9 1 1 0 1 1 1 0 Rnf-Nqr subunit, membrane protein EamA PF00892.15 EWM28333.1 - 5.7 7.0 19.7 0.19 11.7 7.7 2.2 1 1 1 2 2 2 0 EamA-like transporter family Mpv17_PMP22 PF04117.7 EWM28334.1 - 6.2e-16 57.7 0.0 1.1e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family BBS2_Mid PF14783.1 EWM28335.1 - 2.3e-08 33.7 0.0 0.01 15.6 0.0 3.8 4 0 0 4 4 4 2 Ciliary BBSome complex subunit 2, middle region FG-GAP PF01839.18 EWM28335.1 - 4.2e-08 32.6 2.7 0.0059 16.2 0.1 2.7 2 0 0 2 2 2 2 FG-GAP repeat VCBS PF13517.1 EWM28335.1 - 4.5e-06 26.9 2.0 0.046 14.0 0.0 3.5 4 1 0 4 4 4 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.3 EWM28335.1 - 0.0066 15.9 0.1 0.68 9.3 0.0 2.4 2 0 0 2 2 2 1 Insecticide toxin TcdB middle/N-terminal region DUF3639 PF12341.3 EWM28335.1 - 0.076 13.0 0.2 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3639) GTP_EFTU PF00009.22 EWM28338.1 - 2.8e-07 30.1 0.1 0.00016 21.1 0.0 2.7 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EWM28338.1 - 6.9e-07 29.4 0.0 1.1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Miro PF08477.8 EWM28338.1 - 4.3e-06 27.2 0.1 2.5e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein MobB PF03205.9 EWM28338.1 - 4.1e-05 23.2 0.1 9.1e-05 22.1 0.0 1.7 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EWM28338.1 - 6e-05 22.9 0.0 0.00016 21.5 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EWM28338.1 - 0.00011 22.5 0.2 0.00032 21.0 0.0 1.8 1 1 1 2 2 2 1 ABC transporter AAA_22 PF13401.1 EWM28338.1 - 0.00028 21.0 0.0 0.00094 19.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EWM28338.1 - 0.00053 19.7 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 EWM28338.1 - 0.00073 19.4 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Adeno_IVa2 PF02456.10 EWM28338.1 - 0.0014 17.3 0.0 0.0018 17.0 0.0 1.1 1 0 0 1 1 1 1 Adenovirus IVa2 protein AAA_33 PF13671.1 EWM28338.1 - 0.0015 18.4 0.8 0.0051 16.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EWM28338.1 - 0.0017 17.5 0.3 0.0051 15.9 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function, DUF258 AAA PF00004.24 EWM28338.1 - 0.0018 18.4 0.2 0.0035 17.5 0.0 1.8 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 EWM28338.1 - 0.0021 17.0 0.0 0.0027 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.17 EWM28338.1 - 0.0023 18.0 0.0 0.0061 16.7 0.0 1.7 2 0 0 2 2 1 1 RNA helicase NACHT PF05729.7 EWM28338.1 - 0.0032 17.1 0.0 0.0053 16.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_17 PF13207.1 EWM28338.1 - 0.0034 18.2 0.1 0.0063 17.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.10 EWM28338.1 - 0.0046 15.6 0.0 0.0068 15.1 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_28 PF13521.1 EWM28338.1 - 0.0062 16.5 0.8 0.023 14.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 EWM28338.1 - 0.0064 15.9 0.0 1.2 8.5 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.1 EWM28338.1 - 0.012 15.0 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EWM28338.1 - 0.015 15.0 0.1 0.031 14.0 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 EWM28338.1 - 0.028 14.1 0.1 0.082 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EWM28338.1 - 0.03 13.4 1.6 0.16 11.0 0.0 2.2 1 1 1 2 2 2 0 Zeta toxin AAA_30 PF13604.1 EWM28338.1 - 0.033 13.7 0.0 0.078 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 EWM28338.1 - 0.038 13.5 0.0 0.2 11.1 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Viral_helicase1 PF01443.13 EWM28338.1 - 0.042 13.3 1.0 0.056 12.9 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 EWM28338.1 - 0.06 12.7 0.0 0.078 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain SRP54 PF00448.17 EWM28338.1 - 0.066 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_29 PF13555.1 EWM28338.1 - 0.078 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.18 EWM28338.1 - 0.088 12.6 0.4 1.7 8.4 0.0 2.6 2 1 1 3 3 3 0 Dynamin family Guanylate_kin PF00625.16 EWM28338.1 - 0.09 12.2 0.4 0.19 11.1 0.0 1.6 2 0 0 2 2 1 0 Guanylate kinase ATP-synt_ab PF00006.20 EWM28338.1 - 0.099 12.1 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.1 EWM28338.1 - 0.11 12.8 0.5 0.48 10.7 0.0 2.3 3 0 0 3 3 3 0 AAA domain UPF0079 PF02367.12 EWM28338.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 RNA12 PF10443.4 EWM28338.1 - 0.12 10.7 0.0 0.23 9.9 0.0 1.4 1 0 0 1 1 1 0 RNA12 protein AAA_23 PF13476.1 EWM28338.1 - 0.13 12.6 0.8 0.35 11.1 0.0 2.0 1 1 1 2 2 2 0 AAA domain cobW PF02492.14 EWM28338.1 - 0.14 11.5 0.1 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF21 PF01595.15 EWM28341.1 - 0.18 11.0 3.3 0.18 11.0 1.2 1.7 1 1 0 1 1 1 0 Domain of unknown function DUF21 Spt4 PF06093.8 EWM28342.1 - 9.1e-24 83.1 0.1 1.9e-23 82.0 0.0 1.6 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger zf-DHHC PF01529.15 EWM28342.1 - 0.31 10.4 7.8 0.72 9.2 5.4 1.7 1 1 0 1 1 1 0 DHHC palmitoyltransferase DUF966 PF06136.8 EWM28342.1 - 0.4 10.0 13.0 0.54 9.6 9.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF262 PF03235.9 EWM28342.1 - 1.2 9.1 7.3 1.5 8.7 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 CDC27 PF09507.5 EWM28342.1 - 2.2 7.4 30.2 2.6 7.1 20.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 BRX PF08381.6 EWM28344.1 - 0.1 11.6 1.4 1.2 8.2 0.1 2.6 2 0 0 2 2 2 0 Transcription factor regulating root and shoot growth via Pin3 Haemolytic PF01809.13 EWM28345.1 - 1.6e-26 91.6 0.1 3.1e-26 90.7 0.0 1.5 1 0 0 1 1 1 1 Haemolytic domain Fapy_DNA_glyco PF01149.19 EWM28346.1 - 0.094 13.0 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Formamidopyrimidine-DNA glycosylase N-terminal domain DUF2842 PF11003.3 EWM28346.1 - 2.2 8.2 7.9 2.3 8.1 2.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2842) TPR_11 PF13414.1 EWM28347.1 - 2.8e-10 39.6 0.0 1.7e-08 33.9 0.0 1.9 1 1 1 2 2 2 2 TPR repeat TPR_17 PF13431.1 EWM28347.1 - 9e-07 28.6 0.0 0.0067 16.5 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EWM28347.1 - 0.0004 20.0 0.0 0.12 12.3 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EWM28347.1 - 0.0014 19.2 0.0 0.12 13.0 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EWM28347.1 - 0.0053 17.0 0.0 0.011 16.0 0.0 1.6 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 EWM28347.1 - 0.015 15.9 0.2 5.9 7.8 0.0 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EWM28347.1 - 0.03 14.0 0.0 14 5.7 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EWM28347.1 - 0.043 13.4 0.0 3.3 7.4 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4192 PF13830.1 EWM28347.1 - 0.093 12.3 0.0 0.15 11.6 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4192) TPR_9 PF13371.1 EWM28347.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 EWM28348.1 - 7.6e-07 28.6 0.1 1.3e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 EWM28348.1 - 0.011 15.2 0.3 0.011 15.2 0.2 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EWM28348.1 - 0.014 15.2 1.6 0.018 14.9 0.3 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Thr_synth_N PF14821.1 EWM28349.1 - 2.9e-18 65.6 0.0 1.1e-17 63.7 0.0 2.0 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.20 EWM28349.1 - 1.4e-06 27.7 0.1 3.5e-06 26.4 0.1 1.6 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme F-box PF00646.28 EWM28350.1 - 5.7e-05 22.6 1.5 0.00014 21.3 1.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EWM28350.1 - 0.063 13.0 1.2 0.15 11.7 0.9 1.6 1 0 0 1 1 1 0 F-box-like zf-C2H2_7 PF15269.1 EWM28355.1 - 0.44 10.4 2.8 0.36 10.7 0.7 1.7 1 1 1 2 2 2 0 Zinc-finger OAF PF14941.1 EWM28357.1 - 0.063 12.4 0.2 0.15 11.2 0.0 1.6 2 0 0 2 2 2 0 Transcriptional regulator, Out at first IceA2 PF05862.6 EWM28358.1 - 0.011 15.3 0.1 0.02 14.6 0.1 1.4 1 0 0 1 1 1 0 Helicobacter pylori IceA2 protein NuA4 PF09340.5 EWM28361.1 - 8e-12 44.6 0.1 1.6e-11 43.6 0.0 1.6 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Nucleoplasmin PF03066.10 EWM28364.1 - 0.012 15.1 6.5 0.012 15.1 4.5 1.7 2 0 0 2 2 2 0 Nucleoplasmin DUF1738 PF08401.6 EWM28364.1 - 0.043 13.5 0.9 0.073 12.7 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1738) Nop14 PF04147.7 EWM28364.1 - 0.077 10.9 3.1 0.095 10.6 2.2 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_pol_3_Rpc31 PF11705.3 EWM28364.1 - 0.1 12.4 6.8 0.21 11.5 4.7 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2890 PF11081.3 EWM28364.1 - 0.18 11.8 8.5 0.33 10.9 5.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Herpes_pp85 PF04637.7 EWM28364.1 - 0.27 9.4 0.3 0.34 9.1 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) PBP1_TM PF14812.1 EWM28364.1 - 0.3 11.4 6.9 0.27 11.5 3.6 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_pol_phi PF04931.8 EWM28364.1 - 0.35 8.5 7.9 0.51 8.0 5.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi Daxx PF03344.10 EWM28364.1 - 0.51 8.7 8.5 0.68 8.3 5.9 1.2 1 0 0 1 1 1 0 Daxx Family Perilipin PF03036.11 EWM28364.1 - 0.6 8.8 2.6 0.81 8.4 1.8 1.1 1 0 0 1 1 1 0 Perilipin family Radial_spoke PF04712.7 EWM28364.1 - 3.8 6.1 12.4 1.4 7.5 6.9 1.4 2 0 0 2 2 2 0 Radial spokehead-like protein Adeno_terminal PF02459.10 EWM28364.1 - 4.7 5.2 5.0 5.9 4.9 3.5 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Paf1 PF03985.8 EWM28364.1 - 8.1 5.0 9.4 12 4.5 6.5 1.2 1 0 0 1 1 1 0 Paf1 PH PF00169.24 EWM28367.1 - 0.0019 18.3 0.1 0.0034 17.5 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 EWM28367.1 - 0.037 14.0 0.1 0.068 13.2 0.1 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain SR-25 PF10500.4 EWM28368.1 - 0.58 9.6 9.2 0.27 10.6 1.6 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ubiquitin PF00240.18 EWM28370.1 - 0.00046 19.5 0.0 0.00086 18.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EWM28370.1 - 0.013 15.6 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain RAM PF15320.1 EWM28371.1 - 7.5 6.8 9.4 0.48 10.7 1.6 2.2 2 1 0 2 2 2 0 mRNA cap methylation, RNMT-activating mini protein Asparaginase_2 PF01112.13 EWM28374.1 - 3.1e-67 226.5 0.6 4.5e-67 226.0 0.4 1.1 1 0 0 1 1 1 1 Asparaginase zf-MYND PF01753.13 EWM28375.1 - 1.2e-07 31.4 10.6 2.2e-07 30.6 7.4 1.4 1 0 0 1 1 1 1 MYND finger NinF PF05810.7 EWM28375.1 - 0.29 10.9 2.2 0.65 9.8 1.5 1.5 1 0 0 1 1 1 0 NinF protein zf-MYND PF01753.13 EWM28376.1 - 1.4e-07 31.2 10.6 2.5e-07 30.4 7.4 1.4 1 0 0 1 1 1 1 MYND finger NinF PF05810.7 EWM28376.1 - 0.4 10.5 2.2 0.76 9.6 1.5 1.4 1 0 0 1 1 1 0 NinF protein HA2 PF04408.18 EWM28378.1 - 1.8e-20 72.8 0.0 2.2e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Helicase associated domain (HA2) DUF3146 PF11344.3 EWM28378.1 - 0.11 11.9 0.2 0.28 10.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3146) PH PF00169.24 EWM28382.1 - 0.043 14.0 0.1 0.059 13.5 0.1 1.2 1 0 0 1 1 1 0 PH domain Ion_trans PF00520.26 EWM28383.1 - 7.2e-22 77.6 1.2 7.2e-22 77.6 0.9 1.7 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 EWM28383.1 - 3.6e-10 39.4 2.2 3.6e-10 39.4 1.5 2.7 2 1 0 2 2 2 1 Ion channel DUF1282 PF06930.7 EWM28383.1 - 0.045 13.3 0.2 0.045 13.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) Ion_trans PF00520.26 EWM28384.1 - 1.1e-21 76.9 1.2 1.1e-21 76.9 0.9 1.7 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 EWM28384.1 - 3.6e-10 39.4 1.8 3.6e-10 39.4 1.3 2.6 2 1 0 2 2 2 1 Ion channel Ion_trans PF00520.26 EWM28385.1 - 7.2e-22 77.6 1.2 7.2e-22 77.6 0.9 1.7 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 EWM28385.1 - 3.6e-10 39.4 2.2 3.6e-10 39.4 1.5 2.7 2 1 0 2 2 2 1 Ion channel DUF1282 PF06930.7 EWM28385.1 - 0.045 13.3 0.2 0.045 13.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) Nol1_Nop2_Fmu PF01189.12 EWM28387.1 - 9.2e-23 81.0 0.0 5.5e-13 48.9 0.0 2.2 2 0 0 2 2 2 2 NOL1/NOP2/sun family PUA PF01472.15 EWM28387.1 - 2.4e-05 23.9 0.1 4.9e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 PUA domain FtsJ PF01728.14 EWM28387.1 - 0.0093 15.9 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase SET PF00856.23 EWM28390.1 - 9.4e-09 35.7 0.0 0.017 15.4 0.0 3.7 4 0 0 4 4 4 2 SET domain PBP1_TM PF14812.1 EWM28390.1 - 5.2 7.4 9.0 23 5.3 0.3 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ABC2_membrane PF01061.19 EWM28391.1 - 3.1e-17 62.4 19.1 3.4e-17 62.3 13.3 1.0 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 EWM28391.1 - 5.3e-05 22.4 16.7 5.9e-05 22.2 11.6 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF423 PF04241.10 EWM28391.1 - 3.3 7.7 8.4 1.2 9.1 1.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF423) Exo_endo_phos PF03372.18 EWM28392.1 - 9.7e-08 32.2 0.0 1.7e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1375 PF07119.7 EWM28392.1 - 0.091 12.6 1.2 6.5 6.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1375) TP53IP5 PF15331.1 EWM28392.1 - 1 9.2 3.3 1.7 8.5 2.3 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 ESR1_C PF12743.2 EWM28392.1 - 1.1 8.8 4.2 0.75 9.3 0.0 2.9 4 0 0 4 4 4 0 Oestrogen-type nuclear receptor final C-terminal Daxx PF03344.10 EWM28392.1 - 1.3 7.4 23.3 1.9 6.8 16.1 1.1 1 0 0 1 1 1 0 Daxx Family TFIIF_alpha PF05793.7 EWM28392.1 - 5.9 5.1 26.7 8.5 4.6 18.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Glyco_hydro_8 PF01270.12 EWM28394.1 - 1.5e-26 92.9 3.6 2.5e-26 92.2 2.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 8 CASP_C PF08172.7 EWM28396.1 - 1e-52 178.6 0.2 2.4e-52 177.4 0.1 1.6 1 1 1 2 2 2 2 CASP C terminal Striatin PF08232.7 EWM28396.1 - 0.018 15.3 3.9 0.034 14.4 0.0 2.4 2 1 0 2 2 2 0 Striatin family Rootletin PF15035.1 EWM28396.1 - 0.022 14.7 2.9 1.2 9.1 0.3 2.4 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DivIC PF04977.10 EWM28396.1 - 0.57 9.6 4.3 0.5 9.8 0.1 2.6 2 1 1 3 3 3 0 Septum formation initiator Cortex-I_coil PF09304.5 EWM28396.1 - 0.81 9.7 6.0 1.7 8.7 0.8 2.4 2 0 0 2 2 2 0 Cortexillin I, coiled coil bZIP_2 PF07716.10 EWM28396.1 - 9.8 6.0 9.9 6.9 6.5 0.7 3.5 2 2 2 4 4 4 0 Basic region leucine zipper Sulfate_transp PF00916.15 EWM28397.1 - 2.3e-15 56.3 6.4 2.4e-15 56.2 3.3 2.0 1 1 0 1 1 1 1 Sulfate transporter family cNMP_binding PF00027.24 EWM28397.1 - 2.1e-13 49.8 0.0 6.5e-13 48.3 0.0 1.9 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain STAS PF01740.16 EWM28397.1 - 5.3e-06 25.8 0.0 1.8e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 STAS domain Sulfate_transp PF00916.15 EWM28398.1 - 3.1e-15 55.9 5.2 3.1e-15 55.9 3.6 1.8 1 1 0 1 1 1 1 Sulfate transporter family cNMP_binding PF00027.24 EWM28398.1 - 1.7e-13 50.2 0.0 5.8e-13 48.4 0.0 2.0 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain STAS PF01740.16 EWM28398.1 - 4.5e-06 26.0 0.0 1.6e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 STAS domain Sybindin PF04099.7 EWM28399.1 - 1.1e-22 80.2 0.0 1.7e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family RNA_pol_3_Rpc31 PF11705.3 EWM28402.1 - 2.3e-07 31.0 0.0 4.1e-07 30.1 0.0 1.5 1 1 1 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 RNA_pol_3_Rpc31 PF11705.3 EWM28403.1 - 3.1e-07 30.5 0.0 3.5e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 CD36 PF01130.16 EWM28404.1 - 3.3e-29 101.5 0.0 1.7e-20 72.7 0.0 2.5 2 1 0 2 2 2 2 CD36 family PBP1_TM PF14812.1 EWM28404.1 - 0.00051 20.3 1.5 0.00099 19.3 1.1 1.4 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.9 EWM28404.1 - 0.017 13.1 1.1 0.024 12.7 0.8 1.1 1 0 0 1 1 1 0 CDC45-like protein CDV3 PF15359.1 EWM28404.1 - 0.96 9.5 5.5 2.3 8.3 3.8 1.5 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 Sigma70_ner PF04546.8 EWM28404.1 - 2.7 7.5 12.4 4.2 6.9 8.6 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region CobT PF06213.7 EWM28404.1 - 3 6.8 13.8 5.3 6.0 9.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Mpp10 PF04006.7 EWM28404.1 - 3.7 5.8 14.2 5.1 5.3 9.8 1.1 1 0 0 1 1 1 0 Mpp10 protein Nucleoplasmin PF03066.10 EWM28404.1 - 7.6 6.0 18.6 10 5.5 12.3 1.6 2 0 0 2 2 2 0 Nucleoplasmin NOA36 PF06524.7 EWM28404.1 - 7.8 5.6 11.9 11 5.1 8.2 1.1 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.1 EWM28404.1 - 9.1 5.9 6.2 17 5.0 4.3 1.4 1 0 0 1 1 1 0 FAM176 family PBP PF01161.15 EWM28405.1 - 8.4e-20 71.0 0.0 1e-19 70.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein zf-UBP PF02148.14 EWM28406.1 - 2.5e-13 49.8 2.5 1.1e-12 47.8 1.7 2.0 1 1 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein IF3_N PF05198.11 EWM28407.1 - 5.5e-16 58.2 0.1 1e-15 57.3 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain IF3_C PF00707.17 EWM28407.1 - 2.7e-08 33.4 0.0 5.3e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain ABC_tran PF00005.22 EWM28408.1 - 1.2e-41 142.2 0.0 2.1e-26 92.8 0.0 3.9 3 1 0 3 3 3 3 ABC transporter ABC_membrane PF00664.18 EWM28408.1 - 2e-24 86.4 16.5 2.5e-21 76.2 6.0 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EWM28408.1 - 1.5e-07 30.8 0.0 0.039 13.1 0.0 3.2 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EWM28408.1 - 1.7e-05 24.9 0.0 0.49 10.3 0.0 3.4 4 0 0 4 4 4 2 AAA domain MMR_HSR1 PF01926.18 EWM28408.1 - 0.011 15.6 0.2 0.086 12.7 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase CsgG PF03783.9 EWM28408.1 - 0.015 14.3 1.1 0.029 13.4 0.7 1.4 1 0 0 1 1 1 0 Curli production assembly/transport component CsgG Miro PF08477.8 EWM28408.1 - 0.055 13.9 0.1 0.055 13.9 0.1 2.3 3 0 0 3 3 3 0 Miro-like protein Troponin-I_N PF11636.3 EWM28408.1 - 0.08 12.6 1.7 0.21 11.3 0.2 2.6 2 0 0 2 2 2 0 Troponin I residues 1-32 ATP-synt_ab PF00006.20 EWM28408.1 - 0.096 12.1 0.1 0.22 11.0 0.1 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF87 PF01935.12 EWM28408.1 - 0.097 12.4 0.1 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_29 PF13555.1 EWM28408.1 - 0.17 11.4 0.9 0.8 9.2 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain ArgK PF03308.11 EWM28408.1 - 0.34 9.6 2.7 2 7.1 0.2 2.4 3 0 0 3 3 3 0 ArgK protein Abhydrolase_6 PF12697.2 EWM28409.1 - 1.4e-16 61.1 0.2 2.7e-16 60.1 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM28409.1 - 1.1e-08 34.9 0.0 5e-08 32.8 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EWM28409.1 - 4.8e-08 32.8 0.6 9.2e-06 25.3 0.1 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EWM28409.1 - 0.0025 17.0 0.0 0.011 15.0 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_8 PF06259.7 EWM28409.1 - 0.0045 16.5 0.0 0.0079 15.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase LIP PF03583.9 EWM28409.1 - 0.011 14.9 0.0 0.24 10.5 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase BAAT_C PF08840.6 EWM28409.1 - 0.057 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.15 EWM28409.1 - 0.083 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_6 PF12697.2 EWM28410.1 - 1.4e-16 61.1 0.2 2.7e-16 60.1 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM28410.1 - 1.1e-08 34.9 0.0 5e-08 32.8 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EWM28410.1 - 4.8e-08 32.8 0.6 9.2e-06 25.3 0.1 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EWM28410.1 - 0.0025 17.0 0.0 0.011 15.0 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_8 PF06259.7 EWM28410.1 - 0.0045 16.5 0.0 0.0079 15.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase LIP PF03583.9 EWM28410.1 - 0.011 14.9 0.0 0.24 10.5 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase BAAT_C PF08840.6 EWM28410.1 - 0.057 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.15 EWM28410.1 - 0.083 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase PCI_Csn8 PF10075.4 EWM28412.1 - 6.3e-08 32.5 0.0 1.3e-07 31.4 0.0 1.4 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 ABC_membrane PF00664.18 EWM28413.1 - 6.1e-06 25.8 4.1 1.3e-05 24.7 2.9 1.5 1 1 0 1 1 1 1 ABC transporter transmembrane region Pox_P35 PF03213.9 EWM28415.1 - 0.18 10.7 0.8 0.61 9.0 0.1 2.0 1 1 1 2 2 2 0 Poxvirus P35 protein Bacillus_HBL PF05791.6 EWM28415.1 - 0.27 10.5 11.6 1.1 8.6 0.2 3.7 3 1 1 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) WD40 PF00400.27 EWM28416.1 - 5.4e-29 98.9 13.5 3.7e-09 36.1 0.0 6.1 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EWM28416.1 - 0.00087 19.0 0.0 0.0072 16.0 0.0 2.3 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EWM28416.1 - 0.13 10.3 0.0 0.26 9.3 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 ABC_tran PF00005.22 EWM28417.1 - 3.4e-44 150.4 0.0 4.9e-28 98.1 0.0 2.8 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EWM28417.1 - 6.8e-41 140.4 20.0 2.7e-25 89.3 6.8 3.2 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EWM28417.1 - 1.2e-09 37.6 0.2 0.14 11.3 0.0 4.2 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EWM28417.1 - 1.5e-09 38.2 0.0 0.025 14.5 0.0 4.0 4 0 0 4 4 4 3 AAA domain AAA_29 PF13555.1 EWM28417.1 - 2.8e-07 29.9 1.8 0.0039 16.6 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain ArgK PF03308.11 EWM28417.1 - 9.9e-06 24.5 1.1 0.069 11.9 0.2 2.3 2 0 0 2 2 2 2 ArgK protein MMR_HSR1 PF01926.18 EWM28417.1 - 1.7e-05 24.7 0.5 0.012 15.5 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EWM28417.1 - 3.8e-05 23.7 0.7 0.081 12.9 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EWM28417.1 - 5.9e-05 22.5 0.8 0.28 10.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EWM28417.1 - 0.00028 21.6 0.2 0.47 11.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EWM28417.1 - 0.00054 19.6 0.3 0.28 10.8 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EWM28417.1 - 0.00069 20.1 0.3 0.031 14.7 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_10 PF12846.2 EWM28417.1 - 0.0012 18.3 0.5 0.55 9.6 0.0 2.6 2 0 0 2 2 2 1 AAA-like domain T2SE PF00437.15 EWM28417.1 - 0.0015 17.5 0.2 0.14 11.0 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_18 PF13238.1 EWM28417.1 - 0.0019 18.4 0.2 1.4 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EWM28417.1 - 0.0036 16.5 0.4 1.6 7.9 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 EWM28417.1 - 0.0042 17.4 3.5 0.4 10.9 0.0 2.9 3 0 0 3 3 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EWM28417.1 - 0.0092 15.4 0.2 2.6 7.4 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family NTPase_1 PF03266.10 EWM28417.1 - 0.0093 15.6 0.1 1.5 8.5 0.0 2.4 2 0 0 2 2 2 1 NTPase cobW PF02492.14 EWM28417.1 - 0.011 15.1 1.8 0.46 9.9 0.1 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EWM28417.1 - 0.012 15.4 0.1 6 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EWM28417.1 - 0.013 15.6 1.7 3.4 7.7 0.0 3.0 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.7 EWM28417.1 - 0.013 14.5 0.3 3.8 6.5 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_14 PF13173.1 EWM28417.1 - 0.024 14.5 0.2 10 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EWM28417.1 - 0.027 13.3 1.8 0.24 10.2 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.7 EWM28417.1 - 0.04 13.5 2.1 1.9 8.1 0.1 2.8 3 0 0 3 3 2 0 NACHT domain DUF815 PF05673.8 EWM28417.1 - 0.042 12.7 0.0 2.5 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF87 PF01935.12 EWM28417.1 - 0.046 13.5 0.4 0.35 10.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 ATP_bind_1 PF03029.12 EWM28417.1 - 0.047 13.2 0.2 9.8 5.6 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Viral_helicase1 PF01443.13 EWM28417.1 - 0.048 13.1 0.6 0.64 9.4 0.1 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 EWM28417.1 - 0.053 13.2 0.3 8.3 6.0 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA PF00004.24 EWM28417.1 - 0.066 13.4 0.2 17 5.6 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EWM28417.1 - 0.087 12.5 0.8 1 9.1 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain PduV-EutP PF10662.4 EWM28417.1 - 0.13 11.7 1.2 2 7.8 0.2 2.6 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 EWM28417.1 - 0.14 12.0 1.6 16 5.2 0.0 2.7 2 0 0 2 2 2 0 Dynamin family RNA_helicase PF00910.17 EWM28417.1 - 0.16 12.1 0.1 3.1 8.0 0.0 2.4 2 0 0 2 2 2 0 RNA helicase GTP_EFTU PF00009.22 EWM28417.1 - 0.23 10.8 0.0 11 5.4 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain UPF0079 PF02367.12 EWM28417.1 - 0.42 10.2 0.9 3.1 7.4 0.0 2.5 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_PrkA PF08298.6 EWM28417.1 - 0.63 8.6 0.1 5.1 5.6 0.0 2.0 2 0 0 2 2 2 0 PrkA AAA domain AMPKBI PF04739.10 EWM28418.1 - 3.8e-23 81.2 0.5 5.4e-23 80.7 0.3 1.2 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interation domain AAA_5 PF07728.9 EWM28421.1 - 2.1e-24 85.8 0.0 1.8e-23 82.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EWM28421.1 - 2.5e-05 23.8 0.0 6.6e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EWM28421.1 - 7.6e-05 22.6 0.0 0.00033 20.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EWM28421.1 - 0.00013 21.8 0.0 0.00028 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EWM28421.1 - 0.00046 20.1 0.0 0.00074 19.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EWM28421.1 - 0.0014 19.4 0.0 0.0029 18.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EWM28421.1 - 0.0015 17.7 0.4 0.2 10.8 0.1 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 EWM28421.1 - 0.0084 16.1 0.5 0.022 14.7 0.3 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 EWM28421.1 - 0.0097 16.2 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EWM28421.1 - 0.01 15.9 0.0 0.033 14.3 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) LEA_3 PF03242.8 EWM28421.1 - 0.027 14.7 0.0 0.082 13.1 0.0 1.8 2 0 0 2 2 2 0 Late embryogenesis abundant protein Zeta_toxin PF06414.7 EWM28421.1 - 0.053 12.6 0.0 0.091 11.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 EWM28421.1 - 0.054 13.2 0.4 0.21 11.3 0.3 2.0 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 EWM28421.1 - 0.058 13.5 0.3 0.64 10.1 0.2 2.4 1 1 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EWM28421.1 - 0.059 13.0 0.0 0.098 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 EWM28421.1 - 0.065 12.1 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein CPT PF07931.7 EWM28421.1 - 0.14 11.8 0.0 2.3 7.7 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Kinesin PF00225.18 EWM28422.1 - 1e-20 73.7 0.1 2.2e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Mcp5_PH PF12814.2 EWM28422.1 - 0.00097 19.0 0.0 0.037 13.9 0.0 2.4 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology Kinesin PF00225.18 EWM28423.1 - 6.2e-37 127.0 0.4 9.9e-37 126.3 0.0 1.4 2 0 0 2 2 2 1 Kinesin motor domain PIF1 PF05970.9 EWM28423.1 - 0.061 12.2 0.3 0.1 11.4 0.2 1.3 1 0 0 1 1 1 0 PIF1-like helicase DUF707 PF05212.7 EWM28424.1 - 2.2e-30 105.7 2.3 1.7e-29 102.9 1.6 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF707) Mak10 PF04112.8 EWM28426.1 - 1.7e-27 95.7 0.0 3.1e-26 91.5 0.0 2.7 3 0 0 3 3 3 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase L_biotic_typeA PF04604.8 EWM28426.1 - 0.14 11.8 0.1 0.33 10.6 0.1 1.6 1 0 0 1 1 1 0 Type-A lantibiotic eIF3_subunit PF08597.5 EWM28426.1 - 0.44 10.0 2.8 0.77 9.2 0.5 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit VWA_CoxE PF05762.9 EWM28427.1 - 2.4e-05 23.5 0.1 0.014 14.5 0.0 2.3 2 0 0 2 2 2 2 VWA domain containing CoxE-like protein VWA_2 PF13519.1 EWM28427.1 - 0.0014 18.8 0.0 0.0022 18.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Myc_N PF01056.13 EWM28427.1 - 0.045 12.9 0.1 0.045 12.9 0.1 2.3 3 0 0 3 3 3 0 Myc amino-terminal region Totivirus_coat PF05518.6 EWM28427.1 - 6.7 4.3 6.5 4.2 5.0 3.2 1.5 1 1 1 2 2 2 0 Totivirus coat protein Flavodoxin_1 PF00258.20 EWM28428.1 - 1.2e-27 96.6 0.0 2.2e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.15 EWM28428.1 - 3.6e-23 82.1 0.0 5.1e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_3 PF12641.2 EWM28428.1 - 0.042 13.2 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin domain Flavodoxin_5 PF12724.2 EWM28428.1 - 0.046 13.7 0.0 0.08 12.9 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain Flavodoxin_NdrI PF07972.6 EWM28428.1 - 0.05 13.5 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 NrdI Flavodoxin like Pro_isomerase PF00160.16 EWM28429.1 - 9.5e-50 168.8 0.0 1.2e-49 168.5 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Yippee-Mis18 PF03226.9 EWM28430.1 - 2.2e-16 59.6 0.1 2.2e-16 59.6 0.1 1.7 2 0 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly ATPase-cat_bd PF12156.3 EWM28430.1 - 0.17 12.4 0.1 0.17 12.4 0.1 2.6 2 0 0 2 2 2 0 Putative metal-binding domain of cation transport ATPase Nop14 PF04147.7 EWM28430.1 - 0.57 8.0 19.6 0.8 7.5 13.6 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 EWM28430.1 - 2.8 7.1 20.0 5.1 6.2 13.9 1.4 1 0 0 1 1 1 0 SDA1 Nucleo_P87 PF07267.6 EWM28430.1 - 5.5 5.5 6.2 7.4 5.1 4.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 TLD PF07534.11 EWM28431.1 - 2.8e-36 124.5 0.3 3.5e-36 124.2 0.2 1.1 1 0 0 1 1 1 1 TLD HTH_29 PF13551.1 EWM28431.1 - 0.065 13.3 0.3 0.23 11.5 0.1 1.9 2 0 0 2 2 2 0 Winged helix-turn helix DUF35_N PF12172.3 EWM28433.1 - 0.055 13.3 0.8 0.15 11.9 0.6 1.8 1 1 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Cytochrom_B561 PF03188.11 EWM28433.1 - 6.6 6.5 9.3 0.17 11.6 0.9 2.2 2 1 1 3 3 3 0 Eukaryotic cytochrome b561 Cytochrom_B561 PF03188.11 EWM28434.1 - 0.11 12.3 2.8 0.17 11.6 0.9 1.8 1 1 1 2 2 2 0 Eukaryotic cytochrome b561 SNARE_assoc PF09335.6 EWM28436.1 - 2.7e-10 40.5 3.7 4.2e-05 23.7 0.1 3.0 3 0 0 3 3 3 2 SNARE associated Golgi protein GRP PF07172.6 EWM28436.1 - 8.7e-05 22.9 2.1 8.7e-05 22.9 1.5 3.1 4 0 0 4 4 4 1 Glycine rich protein family EVC2_like PF12297.3 EWM28436.1 - 0.02 13.5 0.2 0.5 8.9 0.0 2.2 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein FtsL PF04999.8 EWM28436.1 - 0.025 14.2 2.0 1.1 8.9 0.1 2.6 2 0 0 2 2 2 0 Cell division protein FtsL DUF4131 PF13567.1 EWM28436.1 - 0.062 12.7 7.1 2.3 7.5 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) DUF805 PF05656.9 EWM28436.1 - 0.077 12.8 2.1 3.7 7.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF805) DUF3357 PF11837.3 EWM28436.1 - 0.17 11.7 3.2 0.35 10.7 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) ABC2_membrane PF01061.19 EWM28438.1 - 9.3e-30 103.3 11.1 9.3e-30 103.3 7.7 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 EWM28438.1 - 3.9e-26 91.9 0.0 5.4e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 EWM28438.1 - 1.4e-11 44.0 12.4 2.3e-11 43.3 8.6 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.1 EWM28438.1 - 6e-09 36.2 0.0 4.3e-06 26.9 0.0 2.2 1 1 1 2 2 2 2 AAA domain DUF258 PF03193.11 EWM28438.1 - 0.00012 21.2 0.0 0.00019 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 EWM28438.1 - 0.0056 17.0 0.0 0.0088 16.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 EWM28438.1 - 0.012 14.8 0.0 0.31 10.2 0.0 2.0 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain cobW PF02492.14 EWM28438.1 - 0.024 14.1 0.3 0.04 13.3 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 EWM28438.1 - 0.029 14.3 0.0 0.057 13.4 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 EWM28438.1 - 0.034 13.6 0.2 0.075 12.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.24 EWM28438.1 - 0.042 14.0 0.3 0.52 10.5 0.2 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 EWM28438.1 - 0.059 13.2 0.1 0.33 10.9 0.0 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit RPW8 PF05659.6 EWM28438.1 - 0.088 12.3 0.4 20 4.6 0.2 3.0 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 AAA_22 PF13401.1 EWM28438.1 - 0.13 12.3 0.0 1 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EWM28438.1 - 0.16 11.0 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 EWM28438.1 - 0.2 11.5 0.1 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain V-SNARE_C PF12352.3 EWM28439.1 - 1.5e-11 44.1 1.4 1.5e-11 44.1 1.0 1.8 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EWM28439.1 - 2.5e-06 27.0 0.1 5.8e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Sec20 Mur_ligase_M PF08245.7 EWM28440.1 - 4.7e-10 39.8 0.0 1.3e-09 38.3 0.0 1.6 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 EWM28440.1 - 0.082 12.9 0.0 0.26 11.3 0.0 1.9 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain CENP-B_dimeris PF09026.5 EWM28440.1 - 0.11 12.6 2.0 0.26 11.5 1.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain AMP-binding PF00501.23 EWM28443.1 - 6.6e-23 80.7 0.0 7.3e-23 80.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.23 EWM28444.1 - 2.1e-10 39.5 0.0 2.3e-10 39.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Mito_fiss_reg PF05308.6 EWM28445.1 - 2.1 7.6 6.0 3.3 6.9 4.2 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Ribos_L4_asso_C PF14374.1 EWM28447.1 - 0.067 13.0 0.1 6.7 6.6 0.0 2.2 1 1 1 2 2 2 0 60S ribosomal protein L4 C-terminal domain DUF747 PF05346.6 EWM28448.1 - 4.7e-60 203.3 3.7 5.4e-60 203.1 2.6 1.0 1 0 0 1 1 1 1 Eukaryotic membrane protein family Asp_Arg_Hydrox PF05118.10 EWM28449.1 - 1.3e-30 106.4 0.2 2.3e-14 53.5 0.1 2.2 2 0 0 2 2 2 2 Aspartyl/Asparaginyl beta-hydroxylase Yae1_N PF09811.4 EWM28449.1 - 0.17 11.4 6.9 0.44 10.1 4.8 1.7 1 0 0 1 1 1 0 Essential protein Yae1, N terminal Asp_Arg_Hydrox PF05118.10 EWM28450.1 - 7.2e-28 97.4 0.0 1.7e-14 53.9 0.1 2.1 2 0 0 2 2 2 2 Aspartyl/Asparaginyl beta-hydroxylase Yae1_N PF09811.4 EWM28450.1 - 0.16 11.5 6.9 0.35 10.4 4.8 1.6 1 0 0 1 1 1 0 Essential protein Yae1, N terminal Mem_trans PF03547.13 EWM28452.1 - 0.15 10.3 0.2 0.18 10.0 0.1 1.2 1 0 0 1 1 1 0 Membrane transport protein Spore_coat_CotO PF14153.1 EWM28452.1 - 1.2 8.5 19.7 2.6 7.4 13.7 1.5 1 0 0 1 1 1 0 Spore coat protein CotO NOA36 PF06524.7 EWM28452.1 - 7.4 5.7 13.2 13 4.9 9.1 1.3 1 0 0 1 1 1 0 NOA36 protein Ribosomal_S24e PF01282.14 EWM28456.1 - 8e-30 102.4 0.1 1.7e-29 101.4 0.0 1.6 1 1 1 2 2 2 1 Ribosomal protein S24e BolA PF01722.13 EWM28456.1 - 0.14 12.0 0.5 0.95 9.4 0.1 2.2 1 1 1 2 2 2 0 BolA-like protein GTP_EFTU PF00009.22 EWM28457.1 - 9.9e-60 201.1 0.1 1.4e-59 200.7 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EWM28457.1 - 2.9e-05 24.0 0.0 5.6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EWM28457.1 - 0.0034 17.8 0.0 0.0061 17.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein 2OG-FeII_Oxy PF03171.15 EWM28457.1 - 0.011 16.0 0.0 3 8.1 0.0 2.3 1 1 1 2 2 2 0 2OG-Fe(II) oxygenase superfamily cobW PF02492.14 EWM28457.1 - 0.041 13.3 0.3 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU_D3 PF03143.12 EWM28458.1 - 9.1e-30 102.7 0.0 1.2e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EWM28458.1 - 0.0051 16.9 0.0 0.032 14.3 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 DUF4129 PF13559.1 EWM28459.1 - 0.011 15.6 0.3 8 6.5 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4129) Acetyltransf_1 PF00583.19 EWM28460.1 - 1.4e-16 60.2 0.0 3e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EWM28460.1 - 1.3e-07 31.7 0.0 2.2e-07 30.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EWM28460.1 - 1e-06 28.8 0.0 1.7e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EWM28460.1 - 0.00034 20.4 0.0 0.00074 19.3 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EWM28460.1 - 0.00052 19.7 0.0 0.00096 18.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EWM28460.1 - 0.0013 18.5 0.0 0.0049 16.7 0.0 1.9 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Lentivirus_VIF PF05851.6 EWM28460.1 - 0.051 12.2 1.4 0.082 11.5 1.0 1.2 1 0 0 1 1 1 0 Lentivirus virion infectivity factor (VIF) Acetyltransf_8 PF13523.1 EWM28460.1 - 0.064 13.1 0.0 0.13 12.1 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain dsDNA_bind PF01984.15 EWM28461.1 - 6.1e-27 93.7 6.6 7.6e-27 93.4 4.6 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain HECT PF00632.20 EWM28462.1 - 6.3e-57 193.1 0.0 7.2e-57 192.9 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Spt5_N PF11942.3 EWM28464.1 - 0.083 13.5 3.9 0.14 12.7 2.7 1.4 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal TTL PF03133.10 EWM28465.1 - 2.6e-33 115.1 0.0 8.3e-33 113.5 0.0 1.6 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family LRR_6 PF13516.1 EWM28466.1 - 6.2e-15 53.5 3.6 0.67 10.2 0.0 8.7 9 0 0 9 9 9 4 Leucine Rich repeat LRR_1 PF00560.28 EWM28466.1 - 1.4e-10 39.6 5.4 0.6 10.3 0.0 8.1 7 1 1 8 8 8 3 Leucine Rich Repeat LRR_4 PF12799.2 EWM28466.1 - 4.9e-09 35.5 0.1 0.52 10.0 0.0 5.5 3 1 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EWM28466.1 - 1.7e-06 27.2 14.4 0.71 10.3 0.1 7.8 8 2 0 8 8 8 2 Leucine rich repeat LRR_8 PF13855.1 EWM28466.1 - 2.5e-06 27.1 4.8 0.8 9.5 0.0 4.4 5 1 0 5 5 5 3 Leucine rich repeat F-box-like PF12937.2 EWM28466.1 - 0.00051 19.7 0.1 0.006 16.2 0.0 2.7 2 0 0 2 2 2 1 F-box-like FAD_binding_7 PF03441.9 EWM28467.1 - 1.2e-66 224.8 0.0 1.7e-66 224.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EWM28467.1 - 7.1e-29 100.6 0.0 1.1e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase AIRS_C PF02769.17 EWM28468.1 - 4.1e-07 30.1 0.0 2.7e-06 27.4 0.0 2.2 1 1 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EWM28468.1 - 0.072 13.3 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 AIR synthase related protein, N-terminal domain 7tm_2 PF00002.19 EWM28469.1 - 0.0039 16.2 0.4 0.36 9.8 0.0 2.0 2 0 0 2 2 2 2 7 transmembrane receptor (Secretin family) PLAC8 PF04749.12 EWM28469.1 - 0.19 12.3 1.6 0.43 11.1 0.4 2.0 1 1 1 2 2 2 0 PLAC8 family Cytochrom_B_N_2 PF13631.1 EWM28469.1 - 0.79 9.4 6.9 0.5 10.1 0.3 2.1 1 1 1 2 2 2 0 Cytochrome b(N-terminal)/b6/petB CECR6_TMEM121 PF14997.1 EWM28469.1 - 1.3 8.6 5.8 5.2 6.6 4.0 1.8 1 1 0 1 1 1 0 CECR6/TMEM121 family TMEM18 PF14770.1 EWM28469.1 - 2.9 7.4 6.0 3.4 7.2 0.1 2.9 2 1 1 3 3 3 0 Transmembrane protein 18 DUF3099 PF11298.3 EWM28469.1 - 8 6.2 6.9 1.5 8.6 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3099) EMP24_GP25L PF01105.19 EWM28470.1 - 1.8e-31 109.2 0.0 2.3e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD TMEMspv1-c74-12 PF11044.3 EWM28470.1 - 1.7 8.2 3.8 3.3 7.3 2.6 1.4 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DUF1995 PF09353.5 EWM28471.1 - 1.1e-31 110.1 0.0 1.4e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) PKD_channel PF08016.7 EWM28472.1 - 9.9e-05 20.9 3.3 0.00016 20.2 2.3 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 EWM28472.1 - 0.0041 16.3 6.7 0.0071 15.6 4.7 1.3 1 0 0 1 1 1 1 Ion transport protein COPI_assoc PF08507.5 EWM28473.1 - 1.2e-08 34.7 3.9 1.7e-08 34.2 2.7 1.1 1 0 0 1 1 1 1 COPI associated protein YppG PF14179.1 EWM28473.1 - 0.26 11.8 2.7 0.4 11.2 1.9 1.2 1 0 0 1 1 1 0 YppG-like protein IncA PF04156.9 EWM28473.1 - 1.7 8.1 0.0 1.7 8.1 0.0 2.0 2 0 0 2 2 2 0 IncA protein PPR_3 PF13812.1 EWM28474.1 - 1.5e-12 46.7 19.0 0.094 13.0 0.0 10.1 12 0 0 12 12 12 4 Pentatricopeptide repeat domain PPR PF01535.15 EWM28474.1 - 5.4e-11 41.6 9.4 0.6 10.2 0.0 10.3 10 1 1 11 11 11 4 PPR repeat PPR_2 PF13041.1 EWM28474.1 - 7.9e-09 35.3 1.0 0.0002 21.2 0.0 5.9 5 1 3 8 8 8 1 PPR repeat family PPR_1 PF12854.2 EWM28474.1 - 0.0063 15.9 0.1 0.027 13.9 0.0 2.2 2 0 0 2 2 2 1 PPR repeat MRP-S27 PF10037.4 EWM28474.1 - 0.064 12.1 0.0 0.19 10.6 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 ECSIT PF06239.6 EWM28474.1 - 0.11 11.3 0.0 0.22 10.3 0.0 1.5 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway ThiW PF09512.5 EWM28474.1 - 0.16 11.7 0.1 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Thiamine-precursor transporter protein (ThiW) DUF1336 PF07059.7 EWM28475.1 - 1.2e-40 139.3 0.0 1.1e-33 116.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1336) SlyX PF04102.7 EWM28475.1 - 0.89 9.9 5.5 1.4 9.3 0.2 3.5 2 1 1 3 3 3 0 SlyX Apis_Csd PF11671.3 EWM28475.1 - 1.9 8.2 9.0 0.045 13.5 0.7 2.2 2 0 0 2 2 2 0 Complementary sex determiner protein Rad51 PF08423.6 EWM28476.1 - 5.3e-11 41.9 0.2 6.7e-11 41.5 0.2 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EWM28476.1 - 3.4e-05 23.3 0.1 4.3e-05 23.0 0.1 1.1 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EWM28476.1 - 3.7e-05 22.9 0.1 4.3e-05 22.7 0.1 1.1 1 0 0 1 1 1 1 KaiC RecA PF00154.16 EWM28476.1 - 0.00054 19.1 0.3 0.00063 18.8 0.2 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Zot PF05707.7 EWM28476.1 - 0.0045 16.4 0.1 1.9 7.9 0.0 2.1 2 0 0 2 2 2 2 Zonular occludens toxin (Zot) AAA_33 PF13671.1 EWM28476.1 - 0.021 14.7 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.10 EWM28476.1 - 0.025 13.4 0.0 0.038 12.8 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_19 PF13245.1 EWM28476.1 - 0.051 13.3 0.3 0.051 13.3 0.2 1.8 2 0 0 2 2 1 0 Part of AAA domain PhoH PF02562.11 EWM28476.1 - 0.11 11.7 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.24 EWM28476.1 - 0.14 12.3 0.2 0.2 11.8 0.1 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EWM28476.1 - 0.18 10.7 0.1 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Na_Ca_ex PF01699.19 EWM28478.1 - 3.9e-08 32.9 0.2 5.1e-08 32.6 0.2 1.1 1 0 0 1 1 1 1 Sodium/calcium exchanger protein COX8 PF02285.10 EWM28478.1 - 0.063 12.8 0.8 0.063 12.8 0.5 2.5 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIII WD40 PF00400.27 EWM28479.1 - 1.6e-18 65.8 0.5 3.5e-07 29.8 0.0 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat IBN_N PF03810.14 EWM28480.1 - 6.3e-06 26.0 0.1 2.7e-05 23.9 0.0 2.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EWM28480.1 - 0.00012 22.0 0.0 0.00032 20.6 0.0 1.8 1 0 0 1 1 1 1 Exportin 1-like protein Curlin_rpt PF07012.7 EWM28481.1 - 0.14 11.8 0.1 0.93 9.2 0.1 2.2 2 0 0 2 2 2 0 Curlin associated repeat CRAL_TRIO PF00650.15 EWM28482.1 - 3.4e-20 72.1 0.0 5e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain Epimerase PF01370.16 EWM28483.1 - 1.7e-19 70.1 0.0 4.9e-19 68.7 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EWM28483.1 - 1.2e-14 53.7 0.0 2e-14 52.9 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EWM28483.1 - 4.4e-10 39.8 0.0 1.2e-09 38.4 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 EWM28483.1 - 1.2e-09 37.4 0.1 1.1e-08 34.2 0.0 2.3 2 1 0 2 2 2 1 Male sterility protein NmrA PF05368.8 EWM28483.1 - 6.6e-06 25.5 0.0 1.6e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EWM28483.1 - 0.018 14.9 0.4 0.076 12.9 0.2 2.0 2 1 0 2 2 2 0 short chain dehydrogenase AA_permease_2 PF13520.1 EWM28484.1 - 8.2e-37 126.7 37.0 5.1e-36 124.1 25.6 2.0 1 1 0 1 1 1 1 Amino acid permease His_Phos_1 PF00300.17 EWM28486.1 - 9.7e-33 113.4 0.1 1.3e-32 113.0 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) HrpB4 PF09502.5 EWM28486.1 - 0.0078 15.4 0.1 3.5 6.7 0.0 2.3 2 0 0 2 2 2 2 Bacterial type III secretion protein (HrpB4) DUF72 PF01904.13 EWM28487.1 - 3.6e-53 180.6 0.1 5.1e-53 180.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF72 SNF2_N PF00176.18 EWM28488.1 - 2.4e-65 220.2 0.0 3.2e-65 219.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EWM28488.1 - 9.2e-17 60.6 0.0 2.6e-16 59.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EWM28488.1 - 1e-05 24.4 0.0 1.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 EWM28488.1 - 5.4e-05 22.7 0.0 0.00023 20.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase MAGE PF01454.14 EWM28489.1 - 7.3e-17 61.3 0.0 1.2e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 MAGE family AAA_23 PF13476.1 EWM28490.1 - 2.7e-27 96.4 0.7 2.7e-27 96.4 0.5 7.0 2 1 0 2 2 1 1 AAA domain AAA_13 PF13166.1 EWM28490.1 - 1.5e-10 40.2 8.3 2.3e-08 32.9 5.0 6.5 3 3 0 6 6 6 2 AAA domain AAA_21 PF13304.1 EWM28490.1 - 9.4e-09 35.6 0.0 0.00054 20.0 0.0 2.8 2 1 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EWM28490.1 - 9.9e-09 35.0 0.0 3.2e-08 33.3 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 EWM28490.1 - 7.2e-06 25.3 39.2 9.6e-05 21.7 27.2 2.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EWM28490.1 - 0.00012 21.2 0.0 0.00012 21.2 0.0 4.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EWM28490.1 - 0.0008 18.8 0.0 0.0022 17.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EWM28490.1 - 0.013 15.7 0.0 0.013 15.7 0.0 6.3 5 3 0 5 5 5 0 ABC transporter MobB PF03205.9 EWM28490.1 - 0.027 14.1 0.4 0.26 11.0 0.0 2.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EWM28490.1 - 0.047 13.4 0.0 0.45 10.3 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain NSP2-B_epitope PF14757.1 EWM28490.1 - 0.091 12.2 5.6 1 8.7 0.1 3.0 3 0 0 3 3 3 0 Immunogenic region of nsp2 protein of arterivirus polyprotein MMR_HSR1 PF01926.18 EWM28491.1 - 7.3e-19 67.8 0.0 1.3e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EWM28491.1 - 1e-09 37.8 0.0 1.6e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EWM28491.1 - 7e-05 22.7 2.4 0.025 14.4 0.2 3.1 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 EWM28491.1 - 0.0001 21.4 0.0 0.00021 20.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EWM28491.1 - 0.00015 21.2 0.5 0.0081 15.6 0.0 2.7 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EWM28491.1 - 0.00025 21.5 1.3 0.0011 19.4 0.0 2.4 2 1 0 2 2 2 1 Miro-like protein OmpH PF03938.9 EWM28491.1 - 0.0021 18.0 5.9 0.0034 17.3 4.1 1.3 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) GBP PF02263.14 EWM28491.1 - 0.012 14.7 0.1 0.049 12.6 0.0 2.1 3 0 0 3 3 3 0 Guanylate-binding protein, N-terminal domain IIGP PF05049.8 EWM28491.1 - 0.022 13.6 0.0 0.022 13.6 0.0 1.6 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) SRPRB PF09439.5 EWM28491.1 - 0.028 13.6 0.2 0.065 12.4 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Herpes_DNAp_acc PF04929.7 EWM28491.1 - 0.071 12.0 0.1 0.1 11.5 0.1 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor ABC_tran PF00005.22 EWM28491.1 - 0.099 12.9 0.2 0.3 11.3 0.0 1.8 2 0 0 2 2 2 0 ABC transporter UBN_AB PF14075.1 EWM28491.1 - 1.1 8.9 6.7 1.8 8.2 4.6 1.3 1 0 0 1 1 1 0 Ubinuclein conserved middle domain PP2C PF00481.16 EWM28492.1 - 3.6e-29 101.9 0.1 2.8e-21 76.0 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EWM28492.1 - 7.9e-09 35.2 0.2 6.1e-08 32.3 0.1 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EWM28492.1 - 0.00012 21.8 0.5 0.0006 19.5 0.1 2.0 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) RPA_C PF08784.6 EWM28494.1 - 1.3e-10 41.5 0.8 2.8e-10 40.5 0.2 1.9 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 EWM28494.1 - 2.5e-06 27.2 0.7 4.4e-06 26.4 0.5 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain SET PF00856.23 EWM28495.1 - 4.9e-06 26.9 0.0 8.9e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 SET domain GTP_EFTU PF00009.22 EWM28498.1 - 1.5e-25 89.7 0.0 2.3e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EWM28498.1 - 2.3e-12 46.9 0.0 6.5e-12 45.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 EWM28498.1 - 0.0011 18.8 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EWM28498.1 - 0.0016 17.9 0.0 2.5 7.5 0.0 3.1 3 0 0 3 3 3 2 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 EWM28498.1 - 0.0039 16.8 0.0 0.0081 15.8 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU_D4 PF14578.1 EWM28498.1 - 0.068 12.8 0.2 0.22 11.1 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu domain 4 HypD PF01924.11 EWM28498.1 - 0.079 11.6 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase formation hypA family Exo_endo_phos PF03372.18 EWM28499.1 - 4e-20 72.7 0.0 5.1e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CENP-T PF15511.1 EWM28499.1 - 0.02 14.1 8.7 0.037 13.2 6.0 1.4 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T DEAD PF00270.24 EWM28500.1 - 6.2e-43 146.2 0.1 6.2e-42 142.9 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EWM28500.1 - 2.4e-24 84.9 0.0 7.4e-24 83.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EWM28500.1 - 0.011 15.6 0.0 0.011 15.6 0.0 2.8 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EWM28500.1 - 0.012 14.0 0.3 0.16 10.3 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1253) DUF1162 PF06650.7 EWM28501.1 - 1.9e-20 73.2 0.0 4.9e-19 68.5 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1162) Pex24p PF06398.6 EWM28501.1 - 1.5e-08 33.8 9.5 2.2e-08 33.2 6.6 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin ATG_C PF09333.6 EWM28501.1 - 6.9e-06 26.1 0.0 3.7e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 ATG C terminal domain Metal_CEHH PF14455.1 EWM28501.1 - 0.26 10.6 0.0 0.69 9.2 0.0 1.6 1 0 0 1 1 1 0 Predicted metal binding domain Yae1_N PF09811.4 EWM28502.1 - 8e-07 28.4 7.0 1.4e-06 27.7 4.9 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal RRM_1 PF00076.17 EWM28503.1 - 3.3e-31 106.7 1.0 9.2e-17 60.4 0.1 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM28503.1 - 1.3e-29 101.9 0.0 2.1e-13 50.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM28503.1 - 6.1e-07 29.2 0.2 0.0021 17.8 0.2 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EWM28503.1 - 0.00086 19.0 0.1 0.11 12.2 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif DS PF01916.12 EWM28504.1 - 2.4e-129 430.7 0.0 2.9e-129 430.4 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase XRCC4 PF06632.7 EWM28505.1 - 0.0083 15.0 0.3 0.011 14.6 0.2 1.3 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF4660 PF15559.1 EWM28505.1 - 0.13 12.3 7.7 0.62 10.1 1.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4660) ABC_tran_2 PF12848.2 EWM28506.1 - 1.2 9.0 10.0 0.039 13.7 1.0 2.4 2 0 0 2 2 2 0 ABC transporter Sulfotransfer_3 PF13469.1 EWM28507.1 - 2.9e-15 57.5 0.2 8.6e-15 56.0 0.0 1.9 2 1 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.22 EWM28507.1 - 7.6e-07 28.6 0.1 1.4e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase domain Sulphotransf PF09037.5 EWM28507.1 - 0.061 12.8 0.7 7.4 5.9 0.0 3.3 4 0 0 4 4 4 0 Stf0 sulphotransferase Cytochrom_B558a PF05038.8 EWM28507.1 - 0.067 12.8 0.2 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit DUF3591 PF12157.3 EWM28508.1 - 2e-48 164.9 0.0 5.1e-33 114.1 0.0 3.7 3 1 0 3 3 3 2 Protein of unknown function (DUF3591) RNase_T PF00929.19 EWM28509.1 - 1.7e-25 90.2 0.0 2.6e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EWM28509.1 - 0.00027 20.4 0.0 0.0011 18.4 0.0 1.8 1 1 0 1 1 1 1 3'-5' exonuclease Lipocalin_2 PF08212.7 EWM28512.1 - 1.6e-13 50.6 0.0 2.3e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Lipocalin-like domain TGT PF01702.13 EWM28513.1 - 5.1e-75 251.8 0.0 6.7e-75 251.4 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Isochorismatase PF00857.15 EWM28514.1 - 2.5e-24 86.1 0.3 3.4e-24 85.7 0.2 1.2 1 0 0 1 1 1 1 Isochorismatase family TPMT PF05724.6 EWM28515.1 - 3.5e-32 111.6 0.0 4.4e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.1 EWM28515.1 - 6.9e-07 28.9 0.0 9.2e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM28515.1 - 4.4e-06 26.7 0.0 7.3e-06 25.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM28515.1 - 4.4e-06 27.2 0.0 8.9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM28515.1 - 0.00014 22.1 0.0 0.00021 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM28515.1 - 0.00028 21.3 0.0 0.00041 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM28515.1 - 0.0012 19.2 0.0 0.002 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain HPP PF04982.8 EWM28516.1 - 5.4e-40 135.9 4.9 7.8e-40 135.4 3.4 1.2 1 0 0 1 1 1 1 HPP family DUF3522 PF12036.3 EWM28516.1 - 0.04 13.7 0.1 0.083 12.6 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3522) SBDS_C PF09377.5 EWM28517.1 - 8.4e-31 106.2 0.0 1.5e-30 105.4 0.0 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 EWM28517.1 - 2.3e-28 97.8 0.0 6e-28 96.4 0.0 1.8 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein zf-C2H2_jaz PF12171.3 EWM28517.1 - 0.0083 16.2 0.3 0.016 15.3 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EWM28517.1 - 0.11 12.7 0.2 0.68 10.2 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type GDPD PF03009.12 EWM28518.1 - 1.6e-44 152.3 0.0 1.7e-43 149.0 0.0 2.0 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family AIF_C PF14721.1 EWM28519.1 - 9.7e-14 51.7 0.0 2.9e-07 30.7 0.0 2.4 1 1 1 2 2 2 2 Apoptosis-inducing factor, mitochondrion-associated, C-term Pyr_redox_2 PF07992.9 EWM28519.1 - 7.9e-11 42.2 0.0 1.4e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EWM28519.1 - 6.1e-07 29.7 0.0 1.7e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EWM28519.1 - 0.11 12.7 0.0 27 5.0 0.0 2.9 3 0 0 3 3 3 0 Putative NAD(P)-binding HECT PF00632.20 EWM28520.1 - 1.7e-86 290.2 0.0 2.3e-86 289.8 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1 PF00415.13 EWM28520.1 - 1.5e-46 156.3 35.2 3.6e-10 39.8 0.0 8.4 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EWM28520.1 - 3.2e-42 141.2 40.2 8.2e-08 31.6 1.5 7.3 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat ATP_bind_1 PF03029.12 EWM28521.1 - 2.8e-82 275.8 0.1 3.4e-82 275.5 0.1 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EWM28521.1 - 3.6e-06 26.5 0.0 1.8e-05 24.2 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain cobW PF02492.14 EWM28521.1 - 5.1e-05 22.7 0.0 0.052 12.9 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.15 EWM28521.1 - 0.00013 20.7 0.1 0.15 10.7 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_10 PF12846.2 EWM28521.1 - 0.00018 21.0 0.1 0.00072 19.0 0.1 1.8 1 1 0 1 1 1 1 AAA-like domain CbiA PF01656.18 EWM28521.1 - 0.00023 20.6 0.0 0.00033 20.1 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.17 EWM28521.1 - 0.00073 19.0 0.0 0.0046 16.4 0.0 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_17 PF13207.1 EWM28521.1 - 0.00094 19.9 0.0 0.0065 17.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 EWM28521.1 - 0.0011 18.6 0.1 0.0027 17.3 0.0 1.7 2 0 0 2 2 1 1 Adenylylsulphate kinase Torsin PF06309.6 EWM28521.1 - 0.0011 18.8 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 Torsin PduV-EutP PF10662.4 EWM28521.1 - 0.0013 18.1 0.0 0.0076 15.7 0.0 2.0 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 EWM28521.1 - 0.0014 18.6 0.0 0.0099 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 EWM28521.1 - 0.0014 18.5 0.0 0.003 17.5 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 EWM28521.1 - 0.0017 18.2 0.0 0.0036 17.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.5 EWM28521.1 - 0.0027 16.9 0.0 0.23 10.6 0.0 2.2 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EWM28521.1 - 0.0029 17.7 0.0 0.012 15.7 0.0 2.0 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 EWM28521.1 - 0.0033 17.1 0.0 0.0062 16.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain ArgK PF03308.11 EWM28521.1 - 0.0036 16.1 0.0 0.013 14.2 0.0 1.8 2 0 0 2 2 2 1 ArgK protein FeoB_N PF02421.13 EWM28521.1 - 0.0037 16.5 0.0 0.024 13.9 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B NB-ARC PF00931.17 EWM28521.1 - 0.011 14.6 0.0 0.021 13.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Gtr1_RagA PF04670.7 EWM28521.1 - 0.014 14.5 0.1 1.4 7.9 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region MobB PF03205.9 EWM28521.1 - 0.015 14.9 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Arf PF00025.16 EWM28521.1 - 0.018 14.2 0.1 0.087 12.0 0.1 2.0 2 1 0 2 2 2 0 ADP-ribosylation factor family Zeta_toxin PF06414.7 EWM28521.1 - 0.025 13.6 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 EWM28521.1 - 0.026 14.8 0.0 0.05 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain MipZ PF09140.6 EWM28521.1 - 0.031 13.3 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 ATPase MipZ NTPase_1 PF03266.10 EWM28521.1 - 0.045 13.4 0.0 0.18 11.5 0.0 2.0 1 1 0 1 1 1 0 NTPase KTI12 PF08433.5 EWM28521.1 - 0.05 12.8 0.0 0.074 12.2 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_14 PF13173.1 EWM28521.1 - 0.061 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 EWM28521.1 - 0.064 11.9 0.0 0.088 11.4 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF258 PF03193.11 EWM28521.1 - 0.066 12.3 0.1 0.32 10.1 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Glyco_tranf_2_3 PF13641.1 EWM28521.1 - 0.091 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase like family 2 UPF0079 PF02367.12 EWM28521.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 EWM28521.1 - 0.15 12.0 0.4 2.6 7.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 EWM28521.1 - 0.16 11.4 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TGF_beta_GS PF08515.7 EWM28521.1 - 0.18 11.1 2.4 0.34 10.2 0.0 2.5 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif DUF3645 PF12359.3 EWM28524.1 - 0.085 11.9 0.6 0.18 10.9 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3645) MMS19_N PF14500.1 EWM28526.1 - 8.7e-63 212.0 0.0 4.9e-62 209.5 0.0 2.3 1 1 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 EWM28526.1 - 7.5e-23 80.9 0.0 3.6e-15 55.6 0.0 4.6 4 1 0 4 4 4 3 RNAPII transcription regulator C-terminal Med26 PF08711.6 EWM28527.1 - 3.7e-10 39.1 0.4 9.5e-10 37.8 0.3 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Prenyltrans_1 PF13243.1 EWM28527.1 - 7.2e-05 22.7 0.0 0.016 15.1 0.0 2.9 2 1 0 2 2 2 2 Prenyltransferase-like FXR1P_C PF12235.3 EWM28527.1 - 1.5 8.9 9.9 0.16 12.0 3.3 2.1 2 0 0 2 2 2 0 Fragile X-related 1 protein C terminal CRAL_TRIO PF00650.15 EWM28528.1 - 7.1e-30 103.5 0.0 1e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EWM28528.1 - 0.03 14.2 0.0 0.052 13.4 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain PH PF00169.24 EWM28528.1 - 0.1 12.8 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 PH domain RRM_1 PF00076.17 EWM28529.1 - 2.4e-38 129.5 0.0 1.5e-17 62.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM28529.1 - 4.3e-35 119.5 0.0 3.4e-15 55.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM28529.1 - 4.7e-21 74.3 0.0 2.8e-07 30.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAP PF02037.22 EWM28529.1 - 3.6e-11 42.2 0.4 7.2e-11 41.3 0.3 1.5 1 0 0 1 1 1 1 SAP domain Nup35_RRM_2 PF14605.1 EWM28529.1 - 2.4e-09 36.8 0.0 0.0026 17.4 0.0 2.6 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EWM28529.1 - 0.0014 18.4 4.7 0.062 13.1 0.0 4.1 4 0 0 4 4 4 1 RNA binding motif DUF2361 PF10153.4 EWM28529.1 - 0.64 10.2 4.1 4.2 7.6 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2361) Merozoite_SPAM PF07133.6 EWM28529.1 - 1.5 8.6 16.8 2.5 7.9 11.6 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Daxx PF03344.10 EWM28529.1 - 2.2 6.6 13.8 3.3 6.0 9.5 1.1 1 0 0 1 1 1 0 Daxx Family Herpes_DNAp_acc PF04929.7 EWM28529.1 - 5.7 5.8 7.0 10 4.9 4.9 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Ion_trans PF00520.26 EWM28530.1 - 4.4e-39 133.8 30.8 2.6e-21 75.7 10.8 2.4 2 0 0 2 2 2 2 Ion transport protein DUF3666 PF12408.3 EWM28530.1 - 0.11 11.6 0.2 0.21 10.7 0.1 1.4 1 0 0 1 1 1 0 Ribose-5-phosphate isomerase Acetyltransf_1 PF00583.19 EWM28531.1 - 7.6e-17 61.1 0.0 1.2e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EWM28531.1 - 1.8e-09 37.7 0.1 2.9e-09 37.0 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EWM28531.1 - 3.6e-08 33.4 0.0 6.3e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EWM28531.1 - 4.5e-08 32.7 0.0 8.1e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein DUF3749 PF12568.3 EWM28531.1 - 0.001 18.6 0.0 0.0019 17.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EWM28531.1 - 0.0015 18.3 0.0 0.0023 17.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EWM28531.1 - 0.013 15.7 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EWM28531.1 - 0.028 14.2 0.1 0.07 13.0 0.0 1.7 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Sporozoite_P67 PF05642.6 EWM28531.1 - 1.2 6.8 4.6 1.7 6.4 3.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Tubulin PF00091.20 EWM28533.1 - 3e-71 239.6 0.0 4.4e-71 239.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EWM28533.1 - 1.8e-47 160.4 0.1 2.8e-47 159.8 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EWM28533.1 - 3.1e-05 23.9 0.0 7.2e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EWM28533.1 - 0.0043 16.5 0.0 0.0086 15.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain EXOSC1 PF10447.4 EWM28534.1 - 4.6e-21 74.5 1.5 7.7e-21 73.8 1.1 1.4 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 EWM28534.1 - 8.6e-15 53.7 0.2 1.8e-14 52.7 0.1 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.18 EWM28534.1 - 0.03 14.4 0.5 0.2 11.7 0.3 2.1 1 1 0 1 1 1 0 S1 RNA binding domain LRR_6 PF13516.1 EWM28535.1 - 6.6e-08 31.8 23.3 0.13 12.4 0.1 6.6 6 0 0 6 6 6 3 Leucine Rich repeat LRR_4 PF12799.2 EWM28535.1 - 1.1e-05 24.9 16.4 0.0007 19.1 0.4 4.9 3 2 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EWM28535.1 - 0.0011 18.6 23.0 1.4 9.2 0.0 7.3 7 0 0 7 7 7 3 Leucine Rich Repeat LRR_8 PF13855.1 EWM28535.1 - 1.8 8.3 20.8 1.6 8.5 2.9 4.6 3 2 0 3 3 3 0 Leucine rich repeat SNO PF01174.14 EWM28536.1 - 3.1e-44 150.8 0.0 4.6e-36 124.2 0.0 2.1 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 EWM28536.1 - 1.4e-09 37.6 0.1 6.7e-09 35.5 0.0 2.1 3 0 0 3 3 3 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.12 EWM28536.1 - 0.00015 21.5 0.0 0.00021 21.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 GATase PF00117.23 EWM28536.1 - 0.00023 20.6 0.1 0.075 12.4 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.19 EWM28536.1 - 0.002 17.5 0.0 0.0033 16.8 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_C26 PF07722.8 EWM28536.1 - 0.022 14.2 1.6 1.3 8.4 0.3 3.0 2 1 0 2 2 2 0 Peptidase C26 Amidinotransf PF02274.12 EWM28536.1 - 0.11 11.5 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Amidinotransferase BPL_N PF09825.4 EWM28536.1 - 0.17 10.6 0.1 5.4 5.6 0.0 2.3 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal HTH_11 PF08279.7 EWM28539.1 - 0.057 13.0 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 HTH domain Pertussis_S1 PF02917.9 EWM28539.1 - 0.076 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Pertussis toxin, subunit 1 N6_N4_Mtase PF01555.13 EWM28539.1 - 0.095 12.1 0.1 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 DNA methylase Guanylate_kin PF00625.16 EWM28540.1 - 1.3e-58 197.4 0.0 1.9e-58 196.9 0.0 1.2 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.1 EWM28540.1 - 1.6e-06 28.0 0.0 6.8e-06 26.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain RIIa PF02197.12 EWM28540.1 - 4.5e-05 22.7 0.8 0.00011 21.5 0.6 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit DUF258 PF03193.11 EWM28540.1 - 0.00035 19.7 0.0 0.00092 18.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 EWM28540.1 - 0.003 17.8 0.0 0.014 15.7 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EWM28540.1 - 0.0047 17.7 0.0 0.01 16.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EWM28540.1 - 0.013 15.6 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 EWM28540.1 - 0.043 12.8 0.0 0.067 12.1 0.0 1.3 1 0 0 1 1 1 0 Septin RNA_helicase PF00910.17 EWM28540.1 - 0.047 13.8 0.0 0.088 12.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 EWM28540.1 - 0.077 12.4 0.2 0.17 11.2 0.1 1.5 1 0 0 1 1 1 0 AAA-like domain ABC_tran PF00005.22 EWM28540.1 - 0.082 13.1 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 EWM28540.1 - 0.086 12.8 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 EWM28540.1 - 0.099 12.5 0.1 5 7.0 0.0 2.5 1 1 1 2 2 2 0 AAA domain FKBP_C PF00254.23 EWM28541.1 - 2e-11 43.7 0.1 3.6e-11 42.9 0.1 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Peptidase_M50 PF02163.17 EWM28543.1 - 5e-08 32.1 1.7 4.1e-07 29.1 1.2 2.1 1 1 0 1 1 1 1 Peptidase family M50 Peptidase_M1 PF01433.15 EWM28544.1 - 1.2e-65 222.1 0.0 1.8e-65 221.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EWM28544.1 - 2.4e-38 130.9 0.1 4.9e-38 129.9 0.1 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EWM28544.1 - 1.3e-12 47.8 0.1 2.4e-12 46.9 0.1 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Nup54 PF13874.1 EWM28545.1 - 6.1e-10 38.9 5.2 6.1e-10 38.9 3.6 2.7 4 0 0 4 4 4 1 Nucleoporin complex subunit 54 DUF4105 PF13387.1 EWM28545.1 - 0.0013 17.9 0.0 0.28 10.3 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4105) FUSC PF04632.7 EWM28545.1 - 0.17 10.2 13.9 0.011 14.1 4.9 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family RAB3GAP2_N PF14655.1 EWM28545.1 - 0.22 10.4 3.2 0.47 9.4 2.2 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF1612 PF07756.7 EWM28545.1 - 0.63 10.1 4.4 0.7 9.9 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1612) DUF2203 PF09969.4 EWM28545.1 - 0.95 9.7 3.7 1.6 8.9 0.4 2.7 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Sporozoite_P67 PF05642.6 EWM28545.1 - 4.8 4.9 19.9 9 4.0 13.5 1.5 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Ribosomal_L10 PF00466.15 EWM28546.1 - 1.6e-22 79.2 0.1 3.4e-22 78.2 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EWM28546.1 - 1e-10 41.8 8.4 1.8e-10 41.0 5.8 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein Beta_elim_lyase PF01212.16 EWM28547.1 - 6.9e-83 278.1 0.2 9.6e-83 277.6 0.1 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EWM28547.1 - 7.9e-09 34.9 0.0 1.1e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EWM28547.1 - 1.2e-05 24.5 0.1 0.00077 18.6 0.0 2.5 3 0 0 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EWM28547.1 - 1.8e-05 23.6 0.0 0.00019 20.3 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EWM28547.1 - 0.00024 19.5 0.0 0.0004 18.7 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SNF2_N PF00176.18 EWM28548.1 - 9.4e-10 37.7 0.0 1.4e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain PseudoU_synth_1 PF01416.15 EWM28549.1 - 2.4e-24 85.7 0.0 3e-11 43.6 0.0 3.3 3 0 0 3 3 3 3 tRNA pseudouridine synthase tRNA_NucTran2_2 PF13735.1 EWM28549.1 - 0.02 14.7 0.2 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 tRNA nucleotidyltransferase domain 2 putative Dor1 PF04124.7 EWM28550.1 - 6.6e-48 162.8 2.6 4.7e-23 81.1 0.2 3.6 4 1 0 4 4 4 3 Dor1-like family Diphthamide_syn PF01866.12 EWM28552.1 - 1.9e-56 191.5 0.0 5.1e-33 114.6 0.0 2.1 2 0 0 2 2 2 2 Putative diphthamide synthesis protein SNF2_N PF00176.18 EWM28553.1 - 5.1e-65 219.2 0.1 5.1e-65 219.2 0.0 3.5 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EWM28553.1 - 1.8e-14 53.3 0.1 3.3e-13 49.2 0.0 3.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Linker_histone PF00538.14 EWM28553.1 - 2.7e-06 27.3 0.1 9.5e-06 25.6 0.1 2.0 1 0 0 1 1 1 1 linker histone H1 and H5 family PHD PF00628.24 EWM28553.1 - 0.048 13.3 12.2 0.059 13.0 1.4 2.8 2 0 0 2 2 2 0 PHD-finger PLA2G12 PF06951.6 EWM28555.1 - 2.5e-13 50.0 15.9 1.3e-12 47.6 11.0 1.9 1 1 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) Img2 PF05046.9 EWM28556.1 - 1.1e-13 51.2 0.0 1.6e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Sec1 PF00995.18 EWM28557.1 - 5.9e-92 309.1 0.0 6.8e-92 308.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Sec1 PF00995.18 EWM28558.1 - 5.9e-92 309.1 0.0 6.8e-92 308.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family HNH PF01844.18 EWM28559.1 - 2.2e-13 49.8 1.7 2.2e-13 49.8 1.2 1.8 2 0 0 2 2 2 1 HNH endonuclease HNH_4 PF13395.1 EWM28559.1 - 2.2e-12 46.4 0.0 3.4e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 HNH endonuclease HNH_5 PF14279.1 EWM28559.1 - 6.8e-06 25.9 0.1 1.5e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 HNH endonuclease Endonuclease_7 PF02945.10 EWM28559.1 - 0.024 14.3 1.3 0.051 13.3 0.9 1.5 1 0 0 1 1 1 0 Recombination endonuclease VII Glyco_hydro_8 PF01270.12 EWM28560.1 - 2.6e-30 105.3 2.9 3.6e-30 104.8 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 8 WD40 PF00400.27 EWM28561.1 - 1.5e-06 27.8 0.1 0.032 14.1 0.1 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF3321 PF11968.3 EWM28564.1 - 2.6e-38 131.8 0.0 3.4e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 EWM28564.1 - 0.00058 19.6 0.0 0.0013 18.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain RRM_1 PF00076.17 EWM28565.1 - 1.8e-09 37.0 0.0 3.1e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM28565.1 - 1.8e-08 34.2 0.0 3e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM28565.1 - 2.5e-08 33.6 0.0 5.6e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 EWM28565.1 - 7.1e-06 25.5 1.8 7.1e-06 25.5 1.3 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FYVE PF01363.16 EWM28565.1 - 0.0069 16.2 1.5 0.0091 15.8 0.3 1.8 2 0 0 2 2 2 1 FYVE zinc finger zf-CCCH_2 PF14608.1 EWM28565.1 - 0.021 14.8 3.2 0.1 12.6 2.0 2.2 1 1 1 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type GFO_IDH_MocA PF01408.17 EWM28567.1 - 9.8e-13 48.6 0.4 6.5e-12 46.0 0.3 2.1 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ECH PF00378.15 EWM28568.1 - 4e-41 140.7 0.2 1e-39 136.1 0.1 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Thioredoxin PF00085.15 EWM28569.1 - 0.00033 20.2 0.0 0.0071 16.0 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin Claudin_2 PF13903.1 EWM28570.1 - 0.00027 20.6 16.5 0.00037 20.2 11.4 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction FTR1 PF03239.9 EWM28570.1 - 0.057 12.3 3.4 0.08 11.8 2.3 1.2 1 0 0 1 1 1 0 Iron permease FTR1 family F-box-like PF12937.2 EWM28570.1 - 0.098 12.4 1.1 0.3 10.8 0.7 1.9 1 0 0 1 1 1 0 F-box-like Herpes_U15 PF05613.6 EWM28570.1 - 0.43 10.9 0.0 0.43 10.9 0.0 2.0 3 0 0 3 3 3 0 Human herpesvirus U15 protein WBP-1 PF11669.3 EWM28570.1 - 0.57 10.2 2.9 0.26 11.3 0.1 1.9 2 0 0 2 2 2 0 WW domain-binding protein 1 DuoxA PF10204.4 EWM28570.1 - 1.1 8.3 7.1 0.069 12.2 0.4 2.0 1 1 1 2 2 2 0 Dual oxidase maturation factor RPN7 PF10602.4 EWM28571.1 - 5.5e-40 136.6 5.0 7.8e-40 136.1 3.5 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EWM28571.1 - 7.3e-18 64.8 0.0 2.9e-17 62.8 0.0 2.1 2 0 0 2 2 2 1 PCI domain eIF2A PF08662.6 EWM28572.1 - 1.1e-62 211.2 0.0 1.6e-61 207.4 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PQQ PF01011.16 EWM28572.1 - 0.05 13.1 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat DUF3689 PF12463.3 EWM28574.1 - 2e-43 148.3 0.0 3.2e-42 144.3 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF3689) 60KD_IMP PF02096.15 EWM28575.1 - 1.1e-52 178.5 0.1 1.8e-52 177.9 0.1 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein B56 PF01603.15 EWM28576.1 - 1.1e-52 179.0 0.0 1.8e-52 178.3 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Pkinase PF00069.20 EWM28576.1 - 1.3e-31 109.7 0.0 1.9e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM28576.1 - 3e-18 65.8 0.0 4.6e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AIG1 PF04548.11 EWM28576.1 - 0.047 12.7 0.0 0.081 12.0 0.0 1.2 1 0 0 1 1 1 0 AIG1 family Herpes_US9 PF06072.6 EWM28577.1 - 0.041 13.7 0.5 0.1 12.4 0.3 1.7 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 RRM_1 PF00076.17 EWM28578.1 - 1.6e-34 117.3 0.0 3.9e-18 64.8 0.0 3.9 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM28578.1 - 6.2e-28 96.5 0.0 3.1e-15 55.9 0.0 4.1 4 0 0 4 4 4 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM28578.1 - 6.1e-18 64.4 0.0 1.9e-08 34.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EWM28578.1 - 0.13 12.0 1.0 2.1 8.1 0.1 3.1 4 0 0 4 4 4 0 Limkain b1 GrpE PF01025.14 EWM28579.1 - 2.9e-20 72.4 17.1 2.9e-20 72.4 11.8 2.1 2 1 0 2 2 2 1 GrpE Peptidase_S64 PF08192.6 EWM28579.1 - 0.15 10.3 3.3 0.22 9.8 2.3 1.3 1 0 0 1 1 1 0 Peptidase family S64 PAN_2 PF08276.6 EWM28579.1 - 0.18 11.6 4.2 0.11 12.3 0.4 2.3 2 0 0 2 2 2 0 PAN-like domain HBS1_N PF08938.5 EWM28579.1 - 5 7.3 11.0 1.1 9.4 4.6 2.1 2 0 0 2 2 2 0 HBS1 N-terminus GrpE PF01025.14 EWM28580.1 - 7.3e-08 32.1 14.5 1.8e-07 30.8 9.7 1.8 1 1 0 1 1 1 1 GrpE DUF1202 PF06717.6 EWM28580.1 - 0.062 12.5 0.2 0.09 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) Peptidase_S64 PF08192.6 EWM28580.1 - 0.13 10.5 3.1 0.15 10.3 2.2 1.2 1 0 0 1 1 1 0 Peptidase family S64 RyR PF02026.11 EWM28580.1 - 0.14 12.2 0.4 0.62 10.1 0.2 2.1 1 1 0 1 1 1 0 RyR domain PAN_2 PF08276.6 EWM28580.1 - 0.17 11.7 4.2 0.097 12.5 0.4 2.1 2 0 0 2 2 2 0 PAN-like domain HBS1_N PF08938.5 EWM28580.1 - 0.37 10.9 6.7 0.92 9.6 4.6 1.6 1 0 0 1 1 1 0 HBS1 N-terminus Phlebovirus_NSM PF07246.6 EWM28580.1 - 1.2 8.2 4.7 1.8 7.6 3.2 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF4407 PF14362.1 EWM28580.1 - 2.3 7.1 8.4 3.2 6.6 5.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF327 PF03885.8 EWM28580.1 - 2.7 7.8 8.1 1.5 8.6 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF327) APG6 PF04111.7 EWM28580.1 - 3.7 6.5 12.0 5.2 6.0 8.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EWM28580.1 - 8.6 5.9 15.1 14 5.2 10.4 1.5 1 1 0 1 1 1 0 IncA protein MgtE PF01769.11 EWM28581.1 - 4.8e-11 43.0 3.4 4.8e-11 43.0 2.4 1.9 2 0 0 2 2 2 1 Divalent cation transporter CBS PF00571.23 EWM28581.1 - 9.1e-10 38.1 1.4 1.3e-06 28.1 0.2 2.6 2 0 0 2 2 2 2 CBS domain DUF95 PF01944.12 EWM28581.1 - 0.13 11.8 3.8 0.22 11.1 2.7 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF95 Pkinase PF00069.20 EWM28582.1 - 1e-69 234.5 0.0 1.4e-69 234.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM28582.1 - 5.5e-38 130.5 0.0 8.6e-38 129.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Arb2 PF09757.4 EWM28582.1 - 8.7e-13 48.0 0.0 1.4e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Arb2 domain Kinase-like PF14531.1 EWM28582.1 - 0.0088 15.0 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EWM28582.1 - 0.11 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family GWT1 PF06423.7 EWM28586.1 - 2e-27 95.9 4.8 2e-27 95.9 3.3 2.6 2 0 0 2 2 2 1 GWT1 K_channel_TID PF07941.6 EWM28586.1 - 0.7 10.1 7.3 1.7 8.8 5.1 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Pkinase PF00069.20 EWM28587.1 - 1.6e-51 174.9 0.0 2.1e-36 125.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EWM28587.1 - 1.4e-30 106.2 0.0 1e-24 87.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 EWM28587.1 - 5.5e-18 65.0 0.1 9.6e-18 64.2 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Guanylate_cyc PF00211.15 EWM28587.1 - 1.9e-15 56.7 0.0 4.7e-12 45.6 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Kinase-like PF14531.1 EWM28587.1 - 0.0026 16.7 0.0 0.11 11.4 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 EWM28587.1 - 1 8.1 0.0 1.6 7.5 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 G-patch PF01585.18 EWM28589.1 - 3.4e-11 42.7 0.0 6.2e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EWM28589.1 - 0.00083 19.1 0.6 0.0019 18.0 0.0 1.9 2 0 0 2 2 2 1 DExH-box splicing factor binding site ubiquitin PF00240.18 EWM28590.1 - 5.1e-35 118.7 0.9 8.2e-35 118.0 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 EWM28590.1 - 8e-28 95.7 11.8 1.4e-27 95.0 8.2 1.4 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 EWM28590.1 - 1.7e-20 72.4 0.7 2.7e-20 71.8 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EWM28590.1 - 1.6e-06 28.2 0.5 7.7e-06 26.0 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EWM28590.1 - 0.00053 19.7 0.0 0.0009 18.9 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EWM28590.1 - 0.0092 15.8 0.0 0.025 14.4 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EWM28590.1 - 0.0096 16.0 0.0 0.012 15.7 0.0 1.3 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain TUG-UBL1 PF11470.3 EWM28590.1 - 0.056 13.3 0.1 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 GLUT4 regulating protein TUG ABC1 PF03109.11 EWM28591.1 - 3.7e-26 91.4 0.0 8.3e-26 90.3 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 EWM28591.1 - 2.6e-05 24.0 0.9 0.00026 20.7 0.4 2.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family ABC_membrane PF00664.18 EWM28592.1 - 3.4e-48 164.4 13.0 7.5e-25 87.8 0.9 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EWM28592.1 - 2.9e-47 160.4 0.0 1.6e-26 93.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.1 EWM28592.1 - 2e-09 37.6 0.6 0.0029 17.6 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EWM28592.1 - 7.6e-07 28.5 0.1 0.56 9.3 0.0 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Miro PF08477.8 EWM28592.1 - 2.8e-06 27.8 0.0 0.016 15.6 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 EWM28592.1 - 4.1e-06 26.2 0.0 0.047 13.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 EWM28592.1 - 1.2e-05 24.8 1.3 0.0061 15.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 EWM28592.1 - 1.3e-05 25.1 0.1 0.084 12.8 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 EWM28592.1 - 2.9e-05 24.2 0.5 0.076 13.1 0.0 3.4 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EWM28592.1 - 5e-05 23.3 0.0 0.48 10.3 0.0 3.5 3 1 0 3 3 2 1 AAA domain AAA PF00004.24 EWM28592.1 - 6.6e-05 23.1 0.2 0.3 11.2 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 EWM28592.1 - 8.3e-05 23.0 0.0 0.16 12.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EWM28592.1 - 0.00057 19.6 0.0 0.015 14.9 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase DUF258 PF03193.11 EWM28592.1 - 0.00061 19.0 0.0 0.75 8.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EWM28592.1 - 0.0011 19.7 1.1 2 9.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 EWM28592.1 - 0.0035 16.3 0.1 2.4 7.0 0.0 2.6 3 0 0 3 3 2 2 Protein of unknown function (DUF815) Adeno_IVa2 PF02456.10 EWM28592.1 - 0.004 15.8 0.0 0.047 12.3 0.0 2.1 2 0 0 2 2 2 1 Adenovirus IVa2 protein T2SE PF00437.15 EWM28592.1 - 0.0054 15.6 0.0 1.7 7.4 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Zeta_toxin PF06414.7 EWM28592.1 - 0.0056 15.7 0.0 0.3 10.1 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.7 EWM28592.1 - 0.01 15.5 0.0 1 9.0 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.1 EWM28592.1 - 0.01 15.4 0.2 2 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EWM28592.1 - 0.012 15.4 0.1 3.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Dynamin family DUF87 PF01935.12 EWM28592.1 - 0.013 15.3 0.1 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 RNA_helicase PF00910.17 EWM28592.1 - 0.013 15.6 0.0 0.33 11.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.1 EWM28592.1 - 0.014 15.0 1.0 1.1 8.7 0.5 3.2 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 EWM28592.1 - 0.039 13.6 0.0 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 EWM28592.1 - 0.074 12.7 0.1 2.6 7.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EWM28592.1 - 0.075 12.4 0.1 7.9 5.8 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.1 EWM28592.1 - 0.087 12.7 0.0 9.9 6.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EWM28592.1 - 0.1 11.9 0.1 11 5.2 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_14 PF13173.1 EWM28592.1 - 0.12 12.2 0.0 4.9 7.0 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.1 EWM28592.1 - 0.19 12.0 0.0 16 5.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EWM28592.1 - 0.22 10.3 0.2 15 4.2 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain ResIII PF04851.10 EWM28592.1 - 0.28 10.9 0.1 4.2 7.1 0.0 2.5 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit IncA PF04156.9 EWM28592.1 - 0.65 9.5 4.4 1.6 8.3 0.1 3.1 3 0 0 3 3 2 0 IncA protein eIF-5a PF01287.15 EWM28594.1 - 1.4e-22 79.4 0.0 2.1e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EWM28594.1 - 5.5e-05 22.7 0.1 0.00012 21.6 0.1 1.6 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 EWM28594.1 - 0.00017 21.3 0.2 0.00025 20.8 0.1 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain 6PGD PF00393.14 EWM28595.1 - 5.5e-125 416.3 0.0 6.8e-125 416.0 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EWM28595.1 - 7.2e-46 155.9 0.0 1.1e-45 155.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EWM28595.1 - 0.046 13.7 0.1 0.12 12.4 0.1 1.7 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 3HCDH_N PF02737.13 EWM28595.1 - 0.076 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pep_deformylase PF01327.16 EWM28596.1 - 5.6e-51 172.0 0.0 7.2e-51 171.6 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase Methyltransf_26 PF13659.1 EWM28597.1 - 4.4e-15 55.7 0.0 1.4e-14 54.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EWM28597.1 - 1.4e-06 27.7 0.0 6.4e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase small domain Met_10 PF02475.11 EWM28597.1 - 0.015 14.8 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Cons_hypoth95 PF03602.10 EWM28597.1 - 0.041 13.2 0.0 5.3 6.3 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical protein 95 TPR_12 PF13424.1 EWM28598.1 - 7.3e-08 32.2 12.2 0.019 14.8 0.7 5.0 3 2 2 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.1 EWM28598.1 - 1.2e-07 31.2 8.0 0.08 12.6 0.0 4.2 4 0 0 4 4 4 3 TPR repeat TPR_2 PF07719.12 EWM28598.1 - 0.00044 19.9 10.3 2.1 8.4 0.1 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 EWM28598.1 - 0.018 14.6 3.2 13 5.5 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EWM28598.1 - 0.021 15.0 0.8 0.19 11.9 0.2 2.2 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation TPR_7 PF13176.1 EWM28598.1 - 0.18 11.7 11.6 0.39 10.6 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat ABC2_membrane PF01061.19 EWM28599.1 - 1.2e-29 102.9 19.1 1.2e-29 102.9 13.2 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 EWM28599.1 - 3.7e-26 92.0 0.1 1e-25 90.6 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EWM28599.1 - 4.1e-06 26.9 0.0 0.03 14.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EWM28599.1 - 2.3e-05 24.4 0.1 5.9e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 EWM28599.1 - 0.00049 19.3 0.0 0.0048 16.1 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EWM28599.1 - 0.0031 17.0 0.0 0.0074 15.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EWM28599.1 - 0.0032 16.6 0.0 0.0053 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC2_membrane_3 PF12698.2 EWM28599.1 - 0.011 14.8 23.8 0.016 14.3 16.5 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_17 PF13207.1 EWM28599.1 - 0.013 16.3 0.0 0.025 15.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EWM28599.1 - 0.023 14.5 0.5 0.054 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EWM28599.1 - 0.026 14.6 0.0 0.071 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EWM28599.1 - 0.034 13.5 0.0 0.098 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EWM28599.1 - 0.087 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_18 PF13238.1 EWM28599.1 - 0.13 12.5 0.1 0.32 11.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EWM28599.1 - 0.19 12.0 0.2 0.36 11.1 0.0 1.4 2 0 0 2 2 1 0 AAA domain MobB PF03205.9 EWM28599.1 - 0.22 11.1 0.0 0.4 10.3 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Aa_trans PF01490.13 EWM28600.1 - 1.5 7.2 2.9 2 6.8 2.0 1.1 1 0 0 1 1 1 0 Transmembrane amino acid transporter protein Aa_trans PF01490.13 EWM28601.1 - 1.3 7.4 2.9 1.7 7.0 2.0 1.1 1 0 0 1 1 1 0 Transmembrane amino acid transporter protein Enolase_C PF00113.17 EWM28602.1 - 5.9e-154 511.3 0.1 5.9e-154 511.3 0.1 1.3 2 0 0 2 2 2 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EWM28602.1 - 1.5e-56 189.9 1.0 2.9e-56 189.0 0.7 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MAAL_C PF07476.6 EWM28602.1 - 9e-07 28.0 1.0 1.4e-06 27.4 0.1 1.7 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_C PF13378.1 EWM28602.1 - 0.04 13.8 0.0 0.13 12.2 0.0 1.9 1 0 0 1 1 1 0 Enolase C-terminal domain-like PEMT PF04191.8 EWM28603.1 - 6.6e-12 45.4 2.8 6.6e-12 45.4 2.0 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase MgtC PF02308.11 EWM28603.1 - 0.0035 17.1 2.8 0.072 12.9 0.2 2.3 2 0 0 2 2 2 2 MgtC family ICMT PF04140.9 EWM28603.1 - 0.013 15.6 0.5 0.046 13.9 0.3 2.0 1 1 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family HTH_9 PF08221.6 EWM28604.1 - 4.6e-14 52.0 0.3 1.3e-09 37.8 0.0 4.0 4 0 0 4 4 4 2 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.8 EWM28604.1 - 8.5e-05 22.2 1.7 0.0026 17.3 0.1 3.1 2 1 0 2 2 2 1 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.12 EWM28604.1 - 0.0046 16.4 0.5 0.012 15.1 0.3 1.7 1 0 0 1 1 1 1 TFIIE alpha subunit U3snoRNP10 PF12397.3 EWM28605.1 - 0.03 14.2 0.2 0.059 13.3 0.1 1.5 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 10 DUF2721 PF11026.3 EWM28605.1 - 0.08 12.5 1.2 0.4 10.3 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) RelA_SpoT PF04607.12 EWM28606.1 - 6.7e-22 77.6 0.0 7.9e-16 58.1 0.0 2.5 2 0 0 2 2 2 2 Region found in RelA / SpoT proteins HD_4 PF13328.1 EWM28606.1 - 1.4e-08 34.5 1.7 3.5e-08 33.2 1.2 1.7 1 0 0 1 1 1 1 HD domain EF-hand_5 PF13202.1 EWM28606.1 - 1.1e-06 27.6 0.0 2.8e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.27 EWM28606.1 - 2.3e-05 23.3 0.0 5.1e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EWM28606.1 - 2.5e-05 24.3 0.0 6.2e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EWM28606.1 - 0.00083 19.0 0.0 0.0034 17.1 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.1 EWM28606.1 - 0.018 14.6 0.0 0.04 13.5 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair DUF4010 PF13194.1 EWM28607.1 - 0.045 13.0 2.6 0.065 12.5 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) DUF3255 PF11631.3 EWM28607.1 - 0.12 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3255) AAA_28 PF13521.1 EWM28608.1 - 4e-27 95.1 0.0 7.1e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain DAP3 PF10236.4 EWM28608.1 - 0.0011 17.9 0.0 0.0019 17.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 KTI12 PF08433.5 EWM28608.1 - 0.0069 15.6 0.0 0.014 14.6 0.0 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Thymidylate_kin PF02223.12 EWM28608.1 - 0.039 13.3 0.0 0.092 12.1 0.0 1.6 1 0 0 1 1 1 0 Thymidylate kinase AAA_18 PF13238.1 EWM28608.1 - 0.051 13.8 0.0 0.17 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EWM28608.1 - 0.057 14.2 0.0 0.16 12.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EWM28608.1 - 0.072 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain ArgK PF03308.11 EWM28608.1 - 0.18 10.5 0.0 0.27 9.9 0.0 1.2 1 0 0 1 1 1 0 ArgK protein HLH PF00010.21 EWM28609.1 - 2e-07 30.5 1.4 4.1e-07 29.5 0.9 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_4 PF08448.5 EWM28609.1 - 0.00047 20.1 0.4 0.0011 18.9 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 EWM28609.1 - 0.00058 20.1 0.0 0.0011 19.3 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.1 EWM28609.1 - 0.0046 16.7 0.0 0.0093 15.8 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 EWM28609.1 - 0.089 12.5 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 PAS fold PAS_3 PF08447.6 EWM28609.1 - 0.14 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 PAS fold HLH PF00010.21 EWM28610.1 - 1.9e-07 30.6 1.4 4e-07 29.6 0.9 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_4 PF08448.5 EWM28610.1 - 0.00044 20.2 0.4 0.0011 19.0 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 EWM28610.1 - 0.00056 20.2 0.0 0.0011 19.3 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.1 EWM28610.1 - 0.0045 16.8 0.0 0.0091 15.8 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 EWM28610.1 - 0.087 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 PAS fold PAS_3 PF08447.6 EWM28610.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 PAS fold zf-U1 PF06220.7 EWM28611.1 - 8.1e-10 38.0 2.0 1.7e-09 37.0 0.4 2.0 2 0 0 2 2 2 1 U1 zinc finger CRAL_TRIO PF00650.15 EWM28612.1 - 6.2e-30 103.7 0.0 9.2e-30 103.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EWM28612.1 - 5.7e-06 26.3 0.0 1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain FA_hydroxylase PF04116.8 EWM28613.1 - 2e-15 57.1 12.3 2e-15 57.1 8.5 2.5 2 2 1 3 3 3 1 Fatty acid hydroxylase superfamily PUB PF09409.5 EWM28614.1 - 3.3e-10 39.5 0.0 6.6e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 PUB domain Asp-B-Hydro_N PF05279.6 EWM28614.1 - 1.7 8.4 10.9 2.5 7.8 7.5 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF3584 PF12128.3 EWM28614.1 - 3.1 4.9 20.6 4.3 4.5 14.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4033 PF13225.1 EWM28615.1 - 5.9e-29 99.5 0.1 1.1e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4033) RCC1 PF00415.13 EWM28616.1 - 7.6e-55 182.9 37.5 1.4e-13 50.8 0.1 7.8 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EWM28616.1 - 1.4e-28 97.8 35.7 1.8e-09 36.9 0.4 7.3 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.2 EWM28616.1 - 5.8e-13 48.9 0.0 1.8e-12 47.3 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EWM28616.1 - 1.7e-12 46.4 2.9 1.6e-07 30.7 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EWM28616.1 - 4.3e-12 46.1 0.4 1.3e-11 44.6 0.3 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM28616.1 - 5.6e-09 35.3 1.0 0.00013 21.8 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EWM28616.1 - 4.3e-06 26.7 1.4 0.0072 16.5 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) zf-met PF12874.2 EWM28616.1 - 8.9e-06 25.7 2.2 2.7e-05 24.2 1.5 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EWM28616.1 - 4.8e-05 23.3 1.1 9.2e-05 22.4 0.7 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Amidase PF01425.16 EWM28617.1 - 9.2e-88 294.9 0.0 1.9e-87 293.9 0.0 1.5 1 1 0 1 1 1 1 Amidase Amidase PF01425.16 EWM28618.1 - 9.2e-88 294.9 0.0 1.9e-87 293.9 0.0 1.5 1 1 0 1 1 1 1 Amidase UPF0029 PF01205.14 EWM28619.1 - 1.9e-28 98.3 0.0 3.3e-28 97.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 EWM28619.1 - 9.9e-12 44.7 0.0 1.6e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 RWD domain DUF1428 PF07237.6 EWM28619.1 - 0.084 12.7 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) CBFD_NFYB_HMF PF00808.18 EWM28620.1 - 5.1e-18 64.9 2.8 8.7e-18 64.1 2.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EWM28620.1 - 3.9e-08 33.2 1.1 6.8e-08 32.5 0.1 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 GCD14 PF08704.5 EWM28621.1 - 4.6e-67 226.0 0.2 1.3e-37 129.6 0.0 2.8 2 1 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 EWM28621.1 - 1.6e-06 28.1 0.1 4.6e-06 26.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM28621.1 - 4e-05 24.1 0.0 7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain GCD14_N PF14801.1 EWM28621.1 - 0.00011 21.7 0.1 0.00021 20.8 0.0 1.5 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term PCMT PF01135.14 EWM28621.1 - 0.00038 20.0 0.0 0.00061 19.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EWM28621.1 - 0.00083 18.9 0.0 0.0015 18.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain DUF3275 PF11679.3 EWM28621.1 - 0.053 13.1 0.1 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) CMAS PF02353.15 EWM28621.1 - 0.063 12.3 0.0 0.098 11.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase RrnaAD PF00398.15 EWM28621.1 - 0.081 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_24 PF13578.1 EWM28621.1 - 0.11 13.3 0.1 0.56 11.0 0.1 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EWM28621.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain zf-RING_2 PF13639.1 EWM28622.1 - 8.4e-05 22.3 14.0 8.4e-05 22.3 9.7 2.5 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 EWM28622.1 - 0.00018 21.0 14.5 0.00018 21.0 10.1 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EWM28622.1 - 0.00066 19.6 15.2 0.00066 19.6 10.5 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EWM28622.1 - 0.0078 16.0 15.7 0.0078 16.0 10.9 2.6 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EWM28622.1 - 0.021 14.5 13.5 0.021 14.5 9.4 3.2 4 0 0 4 4 4 0 zinc-RING finger domain zf-MIZ PF02891.15 EWM28622.1 - 0.076 12.5 12.6 0.2 11.2 8.7 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_UBOX PF13445.1 EWM28622.1 - 0.099 12.3 6.9 0.24 11.1 4.8 1.7 1 0 0 1 1 1 0 RING-type zinc-finger NAM-associated PF14303.1 EWM28622.1 - 0.86 9.9 7.2 1.4 9.2 5.0 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain zf-RING_6 PF14835.1 EWM28622.1 - 1 9.1 12.1 0.17 11.6 5.4 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 EWM28622.1 - 6.3 6.4 20.6 2.1 8.0 9.3 2.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Ribosomal_L36 PF00444.13 EWM28624.1 - 4.7e-19 68.0 3.2 7.2e-19 67.4 2.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L36 Crust_neurohorm PF01147.12 EWM28624.1 - 0.12 11.7 0.7 0.22 10.8 0.5 1.4 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family TPP_enzyme_M PF00205.17 EWM28626.1 - 1.1e-23 83.4 0.0 2.3e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.13 EWM28626.1 - 1.1e-20 73.7 0.2 2.9e-20 72.4 0.1 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EWM28626.1 - 2.7e-20 72.4 2.1 1.8e-19 69.7 0.0 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EWM28626.1 - 0.00042 19.3 0.0 0.00077 18.4 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_N PF02776.13 EWM28627.1 - 4.6e-34 117.3 0.2 8.5e-34 116.5 0.0 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EWM28627.1 - 8.7e-24 83.8 0.0 1.4e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Inositol_P PF00459.20 EWM28628.1 - 1.3e-54 185.3 0.0 1.7e-54 184.9 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.15 EWM28628.1 - 0.00045 19.1 0.0 0.0015 17.4 0.0 1.7 2 0 0 2 2 2 1 Fructose-1-6-bisphosphatase FKBP_C PF00254.23 EWM28629.1 - 3.8e-20 71.6 0.0 5.5e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Ribosomal_L37 PF08561.5 EWM28630.1 - 0.081 12.5 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 Methyltransf_26 PF13659.1 EWM28631.1 - 2.5e-11 43.6 0.2 5.4e-11 42.5 0.2 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EWM28631.1 - 0.00012 21.4 0.0 0.00045 19.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EWM28631.1 - 0.00017 22.1 0.0 0.00034 21.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Spermine_synth PF01564.12 EWM28631.1 - 0.0043 16.0 0.0 0.0076 15.2 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase PrmA PF06325.8 EWM28631.1 - 0.067 12.3 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.11 EWM28631.1 - 0.19 11.2 0.1 0.74 9.3 0.0 1.9 2 0 0 2 2 2 0 Met-10+ like-protein Acid_PPase PF12689.2 EWM28632.1 - 7.6e-53 178.6 0.0 9.6e-53 178.2 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase NIF PF03031.13 EWM28632.1 - 2.6e-07 30.4 0.0 3.4e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 EWM28632.1 - 0.0002 21.6 0.1 0.00039 20.6 0.1 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Chlamy_scaf PF09675.5 EWM28632.1 - 0.06 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) PUA PF01472.15 EWM28633.1 - 1.2e-14 53.7 0.1 2.5e-14 52.7 0.1 1.6 1 0 0 1 1 1 1 PUA domain Sulfotransfer_1 PF00685.22 EWM28634.1 - 3.1e-13 49.6 0.0 5.5e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase domain Asp_Arg_Hydrox PF05118.10 EWM28634.1 - 6.5e-08 32.5 0.1 1.4e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Sulfotransfer_3 PF13469.1 EWM28634.1 - 3.6e-05 24.7 4.9 3.6e-05 24.7 3.4 2.3 2 1 0 2 2 2 1 Sulfotransferase family PAP1 PF08601.5 EWM28634.1 - 4.1 6.9 9.0 6.5 6.3 6.2 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Mem_trans PF03547.13 EWM28636.1 - 1.1e-33 116.0 0.0 4.7e-33 114.0 0.0 1.9 1 1 0 1 1 1 1 Membrane transport protein CAP_GLY PF01302.20 EWM28637.1 - 5.6e-14 51.5 0.1 1e-13 50.7 0.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain TPR_11 PF13414.1 EWM28638.1 - 1.8e-17 62.7 8.3 8.1e-13 47.8 0.6 2.8 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 EWM28638.1 - 2.9e-10 39.2 6.9 0.00011 21.8 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat UPF0121 PF03661.8 EWM28638.1 - 8e-10 38.3 1.2 1.6e-05 24.2 0.5 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0121) TPR_1 PF00515.23 EWM28638.1 - 1.8e-08 33.6 1.8 0.0056 16.2 0.0 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EWM28638.1 - 6.5e-05 23.2 13.5 0.00016 22.0 0.6 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EWM28638.1 - 7.3e-05 23.3 11.0 0.0067 17.0 0.6 3.6 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 EWM28638.1 - 0.00046 20.4 3.2 0.13 12.6 0.3 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EWM28638.1 - 0.0026 17.7 0.3 21 5.6 0.0 4.1 2 1 0 2 2 2 0 Tetratricopeptide repeat BTAD PF03704.12 EWM28638.1 - 0.014 15.7 5.8 0.026 14.8 0.3 3.0 2 1 1 3 3 3 0 Bacterial transcriptional activator domain TPR_6 PF13174.1 EWM28638.1 - 0.023 15.1 1.3 11 6.7 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 EWM28638.1 - 0.038 13.8 3.0 1 9.2 0.8 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EWM28638.1 - 0.038 13.9 6.8 1.1 9.2 0.8 3.2 2 1 2 4 4 4 0 Tetratricopeptide repeat zf-CGNR PF11706.3 EWM28639.1 - 0.4 10.2 5.7 3 7.4 0.0 2.7 2 0 0 2 2 2 0 CGNR zinc finger FHA PF00498.21 EWM28640.1 - 5.1e-10 39.3 0.0 9.4e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 FHA domain tRNA_int_end_N2 PF12928.2 EWM28642.1 - 1.1e-11 43.9 0.0 2.2e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term MFMR PF07777.6 EWM28642.1 - 0.013 15.4 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 G-box binding protein MFMR U79_P34 PF03064.11 EWM28642.1 - 1.3 8.4 13.0 0.031 13.8 3.5 1.9 2 0 0 2 2 2 0 HSV U79 / HCMV P34 Metal_resist PF13801.1 EWM28643.1 - 0.12 12.3 0.2 0.12 12.3 0.2 1.9 2 0 0 2 2 2 0 Heavy-metal resistance Snf7 PF03357.16 EWM28644.1 - 3.6e-20 72.0 17.1 4.5e-20 71.7 11.9 1.1 1 0 0 1 1 1 1 Snf7 YlqD PF11068.3 EWM28644.1 - 0.072 13.1 7.6 0.077 13.0 4.6 1.6 1 1 0 1 1 1 0 YlqD protein Allexi_40kDa PF05549.6 EWM28644.1 - 0.23 10.7 3.1 0.25 10.6 1.7 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein LdpA_C PF12617.3 EWM28645.1 - 2.4e-33 114.9 0.0 3.4e-32 111.2 0.0 2.4 2 1 0 2 2 2 1 Iron-Sulfur binding protein C terminal FG-GAP PF01839.18 EWM28646.1 - 5.7e-28 95.8 45.4 8.8e-07 28.4 0.1 6.2 6 0 0 6 6 6 5 FG-GAP repeat VCBS PF13517.1 EWM28646.1 - 2.9e-15 56.3 27.2 3.9e-07 30.3 0.7 5.3 2 1 5 7 7 7 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.3 EWM28646.1 - 0.032 13.6 9.5 3.2 7.1 0.0 4.9 3 2 2 5 5 5 0 Insecticide toxin TcdB middle/N-terminal region FG-GAP_2 PF14312.1 EWM28646.1 - 0.13 12.2 17.4 0.51 10.3 0.1 5.6 5 0 0 5 5 5 0 FG-GAP repeat DUF4113 PF13438.1 EWM28647.1 - 0.09 12.3 0.0 0.33 10.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4113) FtsJ PF01728.14 EWM28648.1 - 2.7e-26 92.6 0.0 5.4e-26 91.6 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase DUF2408 PF10303.4 EWM28651.1 - 2.5e-20 72.9 1.4 5.3e-12 46.0 0.1 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF2408) COG2 PF06148.6 EWM28651.1 - 0.012 15.5 2.1 3.7 7.4 0.0 3.2 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF972 PF06156.8 EWM28651.1 - 0.029 14.7 4.7 0.87 9.9 0.1 3.4 2 1 0 3 3 3 0 Protein of unknown function (DUF972) RmuC PF02646.11 EWM28651.1 - 0.035 12.9 0.2 0.17 10.6 0.0 2.0 1 1 1 2 2 2 0 RmuC family Spc24 PF08286.6 EWM28651.1 - 0.11 12.1 0.8 4.8 6.9 0.0 2.6 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 GAS PF13851.1 EWM28651.1 - 0.12 11.5 5.7 0.076 12.2 2.0 2.1 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding HrpB7 PF09486.5 EWM28651.1 - 0.13 12.2 3.2 0.96 9.3 0.1 3.0 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) XhlA PF10779.4 EWM28651.1 - 0.14 12.1 0.2 2.2 8.2 0.1 2.4 2 0 0 2 2 2 0 Haemolysin XhlA Snapin_Pallidin PF14712.1 EWM28651.1 - 0.15 12.3 5.6 7.3 6.9 0.0 3.8 4 2 1 5 5 4 0 Snapin/Pallidin DUF4201 PF13870.1 EWM28651.1 - 0.18 11.2 6.3 8.2 5.8 1.8 2.8 2 1 0 3 3 3 0 Domain of unknown function (DUF4201) Matrilin_ccoil PF10393.4 EWM28651.1 - 0.34 10.2 2.3 1.2 8.5 0.0 3.0 3 1 1 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin Erp_C PF06780.6 EWM28651.1 - 0.46 10.3 3.4 14 5.4 0.0 3.2 3 1 0 3 3 3 0 Erp protein C-terminus CorA PF01544.13 EWM28651.1 - 0.73 8.8 3.7 1.3 8.0 2.1 1.7 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Sas10_Utp3 PF04000.10 EWM28651.1 - 3.1 8.0 5.3 8.4 6.6 0.6 3.2 3 1 0 3 3 3 0 Sas10/Utp3/C1D family Herpes_capsid PF06112.6 EWM28652.1 - 1.3 9.0 4.9 1.5 8.8 3.4 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein KBP_C PF12309.3 EWM28653.1 - 6.7e-50 170.1 0.0 2.2e-49 168.4 0.0 1.8 1 1 0 1 1 1 1 KIF-1 binding protein C terminal TPR_8 PF13181.1 EWM28653.1 - 0.41 10.5 2.9 6.9 6.7 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 EWM28653.1 - 1.9 8.5 9.2 3.1 7.8 0.8 3.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_transf_8 PF01501.15 EWM28655.1 - 8e-26 90.8 0.0 1.3e-25 90.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EWM28655.1 - 0.0035 16.7 0.0 0.0048 16.2 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Rpr2 PF04032.11 EWM28656.1 - 2e-08 33.9 0.7 3.9e-08 33.0 0.5 1.5 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Aldo_ket_red PF00248.16 EWM28657.1 - 3.8e-53 180.1 0.0 4.7e-53 179.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Big_3_2 PF12245.3 EWM28658.1 - 0.0034 16.8 1.5 2.4 7.7 0.0 2.7 2 0 0 2 2 2 2 Bacterial Ig-like domain (group 3) A2M_N PF01835.14 EWM28658.1 - 0.046 13.9 0.5 3.8 7.8 0.0 3.7 3 1 1 4 4 4 0 MG2 domain UQ_con PF00179.21 EWM28659.1 - 2e-37 127.7 0.0 3.2e-37 127.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Arabino_trans_C PF14896.1 EWM28659.1 - 0.05 12.2 0.2 0.071 11.6 0.1 1.1 1 0 0 1 1 1 0 EmbC C-terminal domain PPR_3 PF13812.1 EWM28661.1 - 7e-22 75.8 3.3 5.7e-07 29.3 0.0 5.1 5 0 0 5 5 5 4 Pentatricopeptide repeat domain PPR_2 PF13041.1 EWM28661.1 - 5.6e-20 71.0 0.0 5e-09 35.9 0.0 4.0 2 1 2 4 4 4 4 PPR repeat family PPR PF01535.15 EWM28661.1 - 2.6e-17 61.4 2.1 0.00034 20.3 0.0 4.6 5 0 0 5 5 5 3 PPR repeat PPR_1 PF12854.2 EWM28661.1 - 5.2e-12 45.0 0.0 0.0068 15.8 0.0 4.5 5 0 0 5 5 5 3 PPR repeat Clathrin PF00637.15 EWM28661.1 - 2.2e-05 24.0 0.0 0.0055 16.3 0.0 2.8 2 1 0 2 2 2 1 Region in Clathrin and VPS TPR_16 PF13432.1 EWM28661.1 - 0.024 15.3 0.0 0.33 11.6 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Rep_fac_C PF08542.6 EWM28661.1 - 0.098 12.6 0.1 5.7 6.9 0.0 2.5 3 0 0 3 3 3 0 Replication factor C C-terminal domain SLT_L PF14718.1 EWM28661.1 - 0.11 12.2 1.2 15 5.4 0.1 3.3 4 0 0 4 4 4 0 Soluble lytic murein transglycosylase L domain C6 PF01681.12 EWM28661.1 - 0.14 12.1 1.1 3.2 7.8 0.1 2.3 1 1 1 2 2 2 0 C6 domain HrpB1_HrpK PF09613.5 EWM28661.1 - 0.22 11.0 2.6 10 5.5 0.1 2.8 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) DEAD PF00270.24 EWM28662.1 - 1.8e-24 86.1 0.0 2.8e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EWM28662.1 - 1.7e-09 37.8 0.0 2.7e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Sec63 PF02889.11 EWM28662.1 - 3.2e-09 36.4 0.0 4.6e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain Helicase_C PF00271.26 EWM28662.1 - 1.5e-08 34.3 0.0 3.6e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EWM28662.1 - 0.0014 18.8 0.0 0.0042 17.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain SNF2_N PF00176.18 EWM28662.1 - 0.049 12.4 0.0 0.091 11.5 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_25 PF13481.1 EWM28662.1 - 0.053 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EWM28662.1 - 0.088 12.5 0.1 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain zf-RING_2 PF13639.1 EWM28663.1 - 0.001 18.8 7.2 0.0027 17.5 5.0 1.8 1 0 0 1 1 1 1 Ring finger domain SWIM PF04434.12 EWM28663.1 - 0.0058 16.0 0.1 0.013 14.9 0.1 1.6 1 0 0 1 1 1 1 SWIM zinc finger PHD PF00628.24 EWM28663.1 - 0.027 14.1 5.2 0.058 13.0 3.6 1.6 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 EWM28663.1 - 0.071 13.0 2.1 0.17 11.9 1.4 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.1 EWM28663.1 - 2.7 7.7 10.5 0.06 13.0 2.1 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 C1_1 PF00130.17 EWM28663.1 - 6.1 6.6 9.0 0.43 10.3 1.7 2.3 1 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SHNi-TPR PF10516.4 EWM28664.1 - 1e-08 34.2 0.2 2.4e-07 29.8 0.1 2.4 2 0 0 2 2 2 1 SHNi-TPR TPR_11 PF13414.1 EWM28664.1 - 1.2e-07 31.2 3.5 0.0026 17.3 0.2 2.8 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EWM28664.1 - 4.9e-07 29.0 6.5 0.00092 18.7 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EWM28664.1 - 1.1e-06 28.5 9.9 0.00027 20.7 0.7 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EWM28664.1 - 4.5e-06 26.1 7.3 0.013 15.3 0.0 4.3 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EWM28664.1 - 2.1e-05 23.9 2.3 0.085 12.6 0.0 3.2 4 0 0 4 4 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EWM28664.1 - 0.0024 18.3 4.5 1.7 9.4 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 EWM28664.1 - 0.0038 17.1 0.2 2 8.4 0.0 3.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EWM28664.1 - 0.0065 16.5 1.1 23 5.5 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EWM28664.1 - 0.0076 16.9 4.5 1.5 9.6 0.4 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EWM28664.1 - 0.017 15.5 4.4 2.7 8.6 0.1 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EWM28664.1 - 0.065 13.5 4.4 3.3 8.1 0.1 3.1 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EWM28664.1 - 0.07 12.9 6.2 1.4 8.9 0.1 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat PPR_1 PF12854.2 EWM28664.1 - 0.17 11.4 0.2 0.32 10.4 0.1 1.4 1 0 0 1 1 1 0 PPR repeat Chloroa_b-bind PF00504.16 EWM28665.1 - 2e-35 122.3 0.1 3.3e-35 121.6 0.1 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein RNA_pol_Rpb1_2 PF00623.15 EWM28665.1 - 4.2e-18 65.8 0.0 7.1e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.7 EWM28665.1 - 5.1e-17 62.1 0.1 2e-16 60.1 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 adh_short PF00106.20 EWM28666.1 - 1.8e-26 93.0 0.2 3.4e-26 92.1 0.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EWM28666.1 - 4.6e-16 59.3 0.0 6.9e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EWM28666.1 - 1.2e-09 38.1 0.1 2.2e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EWM28666.1 - 1.8e-08 33.9 0.0 9.4e-07 28.2 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EWM28666.1 - 0.0093 15.9 0.0 0.017 15.1 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding DSPc PF00782.15 EWM28667.1 - 6.5e-16 58.1 0.0 9.7e-16 57.5 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EWM28667.1 - 0.013 14.8 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EWM28667.1 - 0.043 13.8 0.0 0.091 12.8 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Init_tRNA_PT PF04179.7 EWM28667.1 - 0.099 11.4 0.1 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase V-ATPase_G PF03179.10 EWM28668.1 - 2.7e-20 72.5 7.1 3.3e-17 62.7 0.6 2.2 2 0 0 2 2 2 2 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.3 EWM28668.1 - 0.054 12.7 0.0 0.13 11.4 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) SUI1 PF01253.17 EWM28669.1 - 4.6e-17 61.5 0.1 9.1e-17 60.6 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 Rab5ip PF07019.7 EWM28670.1 - 4.7e-05 23.4 1.1 6.2e-05 23.0 0.3 1.4 2 0 0 2 2 2 1 Rab5-interacting protein (Rab5ip) zf-C3HC PF07967.8 EWM28671.1 - 2.7e-26 91.8 0.1 2.4e-21 75.8 1.0 3.2 2 1 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.5 EWM28671.1 - 4.6e-05 23.1 5.9 0.21 11.4 0.0 4.0 3 1 0 3 3 3 3 Rsm1-like Sgf11 PF08209.6 EWM28671.1 - 0.016 14.5 1.3 0.023 13.9 0.0 1.9 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Cys_Met_Meta_PP PF01053.15 EWM28673.1 - 1.2e-143 478.0 0.0 1.4e-143 477.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EWM28673.1 - 0.00033 19.8 1.5 0.00033 19.8 1.1 2.5 2 1 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EWM28673.1 - 0.016 13.9 0.3 0.085 11.5 0.0 1.9 2 0 0 2 2 2 0 Aminotransferase class-V Beta_elim_lyase PF01212.16 EWM28673.1 - 0.1 11.7 0.2 0.68 9.0 0.1 2.2 1 1 0 1 1 1 0 Beta-eliminating lyase AA_permease_2 PF13520.1 EWM28674.1 - 1.1e-51 175.6 22.9 1.6e-51 175.1 15.9 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EWM28674.1 - 4.1e-25 88.0 22.7 6e-25 87.5 15.7 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.1 EWM28674.1 - 5.8e-08 32.4 8.7 5.8e-08 32.4 6.0 3.1 3 0 0 3 3 3 1 C-terminus of AA_permease Spore_permease PF03845.8 EWM28674.1 - 0.00011 21.0 11.3 0.00015 20.5 5.0 2.5 2 1 0 2 2 2 1 Spore germination protein Spindle_Spc25 PF08234.7 EWM28675.1 - 1.1e-22 79.7 0.4 2.2e-22 78.8 0.3 1.5 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 CCDC92 PF14916.1 EWM28675.1 - 0.0024 17.4 2.2 0.0067 15.9 1.5 1.7 1 0 0 1 1 1 1 Coiled-coil domain of unknown function RE_CfrBI PF09516.5 EWM28675.1 - 0.01 14.7 0.6 0.012 14.4 0.4 1.1 1 0 0 1 1 1 0 CfrBI restriction endonuclease CENP-F_leu_zip PF10473.4 EWM28675.1 - 0.051 13.4 16.0 0.11 12.3 8.8 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-PARP PF00645.13 EWM28675.1 - 0.12 12.6 0.1 0.26 11.5 0.1 1.5 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region SseC PF04888.7 EWM28675.1 - 0.14 11.4 4.2 0.21 10.9 2.9 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Cluap1 PF10234.4 EWM28675.1 - 0.28 10.3 7.4 0.44 9.6 5.1 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 Nsp1_C PF05064.8 EWM28675.1 - 0.32 10.6 6.3 0.83 9.3 1.8 2.3 2 0 0 2 2 2 0 Nsp1-like C-terminal region EMP24_GP25L PF01105.19 EWM28675.1 - 0.37 10.4 3.9 0.52 10.0 1.9 1.9 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD COG2 PF06148.6 EWM28675.1 - 0.59 10.0 5.2 0.49 10.2 1.2 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4164 PF13747.1 EWM28675.1 - 0.6 10.2 21.5 0.17 12.0 5.2 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Ax_dynein_light PF10211.4 EWM28675.1 - 1.1 9.1 10.3 2.7 7.8 3.2 2.4 1 1 2 3 3 3 0 Axonemal dynein light chain Spc24 PF08286.6 EWM28675.1 - 3.1 7.5 7.6 0.76 9.4 1.2 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 FUSC PF04632.7 EWM28675.1 - 3.4 5.9 13.9 4.6 5.5 9.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family VSG_B PF13206.1 EWM28675.1 - 3.9 6.5 8.7 4.9 6.1 6.1 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain APG6 PF04111.7 EWM28675.1 - 4.5 6.2 14.8 2.1 7.2 7.9 1.8 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF2562 PF10814.3 EWM28675.1 - 6.9 6.6 6.1 7.5 6.5 1.9 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2562) ADIP PF11559.3 EWM28675.1 - 8.4 6.2 14.6 1.3 8.8 5.8 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding MAPEG PF01124.13 EWM28676.1 - 4.7e-16 58.5 0.2 1.1e-15 57.3 0.1 1.5 1 1 0 1 1 1 1 MAPEG family Peptidase_S10 PF00450.17 EWM28677.1 - 5.3e-119 398.0 0.1 6.3e-119 397.8 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase EF_TS PF00889.14 EWM28678.1 - 2.5e-55 187.2 0.0 3.3e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 Elongation factor TS UBA PF00627.26 EWM28678.1 - 0.0075 16.0 0.0 0.02 14.6 0.0 1.8 1 1 0 1 1 1 1 UBA/TS-N domain Bromodomain PF00439.20 EWM28679.1 - 1.3e-14 53.8 0.0 2.5e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Bromodomain tRNA-synt_2d PF01409.15 EWM28680.1 - 1.9e-46 158.3 0.6 1e-45 155.8 0.4 2.0 1 1 0 1 1 1 1 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 EWM28680.1 - 2.9e-23 81.8 0.0 5.5e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.15 EWM28680.1 - 0.086 11.5 0.1 5.6 5.6 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) TauE PF01925.14 EWM28681.1 - 2.8e-25 89.1 25.3 3.7e-13 49.5 4.8 2.4 1 1 1 2 2 2 2 Sulfite exporter TauE/SafE SpoIIIAH PF12685.2 EWM28681.1 - 0.1 12.0 0.1 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein ALMT PF11744.3 EWM28681.1 - 5.6 5.5 11.3 0.74 8.3 4.2 2.0 2 1 0 2 2 2 0 Aluminium activated malate transporter Epimerase PF01370.16 EWM28682.1 - 5.6e-13 48.8 0.0 7.8e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Parvo_coat PF00740.13 EWM28682.1 - 0.079 11.8 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 RrnaAD PF00398.15 EWM28683.1 - 2.8e-54 183.8 0.1 3.5e-54 183.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EWM28683.1 - 7.2e-10 38.9 0.2 1.4e-09 37.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM28683.1 - 6.2e-07 29.9 0.0 9.8e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EWM28683.1 - 4e-05 23.0 0.0 7.3e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EWM28683.1 - 0.00035 20.2 0.0 0.00055 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EWM28683.1 - 0.00038 19.5 0.0 0.00063 18.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.14 EWM28683.1 - 0.0019 17.7 0.1 0.0029 17.1 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 EWM28683.1 - 0.0089 16.3 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EWM28683.1 - 0.061 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Met_10 PF02475.11 EWM28683.1 - 0.066 12.7 0.2 0.15 11.6 0.1 1.5 2 0 0 2 2 2 0 Met-10+ like-protein BAR PF03114.13 EWM28684.1 - 6.7e-15 55.2 0.0 1.4e-14 54.1 0.0 1.5 1 1 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EWM28684.1 - 6.6e-14 51.0 0.1 1.1e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EWM28684.1 - 1e-13 50.5 0.0 1.8e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EWM28684.1 - 1.1e-09 37.6 0.0 1.9e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF187 PF02638.10 EWM28684.1 - 0.073 11.9 0.1 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase like GH101 CPSase_L_D2 PF02786.12 EWM28685.1 - 4.6e-76 254.7 0.1 7.9e-76 254.0 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 EWM28685.1 - 2.8e-61 206.3 0.0 4.6e-61 205.6 0.0 1.3 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 EWM28685.1 - 1.1e-32 112.4 0.0 2.5e-32 111.2 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EWM28685.1 - 6.7e-32 109.6 0.0 1.7e-31 108.3 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 EWM28685.1 - 1.6e-23 83.6 0.0 4.3e-23 82.1 0.0 1.8 1 0 0 1 1 1 1 HMGL-like ATP-grasp_4 PF13535.1 EWM28685.1 - 1.2e-18 67.4 0.1 2.4e-18 66.5 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EWM28685.1 - 3.5e-18 64.9 3.9 9.8e-18 63.5 2.4 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EWM28685.1 - 1.2e-15 57.1 0.0 2e-14 53.1 0.0 2.5 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 EWM28685.1 - 2.2e-09 36.8 2.1 5e-08 32.4 0.1 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 EWM28685.1 - 1e-08 34.7 0.0 2.2e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EWM28685.1 - 1.8e-08 33.9 0.1 8.2e-08 31.7 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.6 EWM28685.1 - 4e-05 23.1 0.0 0.00024 20.6 0.0 2.1 1 1 0 1 1 1 1 RimK-like ATP-grasp domain NQRA PF05896.6 EWM28685.1 - 0.00016 20.9 0.2 0.00026 20.2 0.2 1.3 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) HlyD PF00529.15 EWM28685.1 - 0.00073 18.9 2.5 0.046 13.0 0.3 2.5 1 1 1 2 2 2 1 HlyD family secretion protein ATP-grasp_3 PF02655.9 EWM28685.1 - 0.0011 18.8 0.0 0.0046 16.8 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 EWM28685.1 - 0.0018 18.5 3.1 0.25 11.7 0.1 2.9 3 0 0 3 3 3 1 HlyD family secretion protein DUF3182 PF11379.3 EWM28685.1 - 0.0057 15.3 0.0 0.011 14.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3182) HlyD_2 PF12700.2 EWM28685.1 - 0.044 12.9 0.4 2.1 7.3 0.1 2.3 1 1 1 2 2 2 0 HlyD family secretion protein GARS_A PF01071.14 EWM28685.1 - 0.07 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GCV_H PF01597.14 EWM28685.1 - 0.2 11.3 0.0 13 5.4 0.1 2.5 2 0 0 2 2 2 0 Glycine cleavage H-protein Exo_endo_phos PF03372.18 EWM28686.1 - 8.6e-15 55.3 0.0 4.2e-14 53.0 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EWM28686.1 - 0.004 16.7 0.0 0.015 14.9 0.0 1.9 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase DUF1295 PF06966.7 EWM28688.1 - 1.7e-53 181.3 0.9 2.2e-53 180.9 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EWM28688.1 - 6.8e-06 26.1 0.1 6.8e-06 26.1 0.1 2.3 3 1 0 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.9 EWM28688.1 - 0.0019 18.3 1.3 0.0053 16.9 0.0 2.3 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.11 EWM28688.1 - 0.03 14.1 0.0 0.07 12.8 0.0 1.6 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase WD40 PF00400.27 EWM28689.1 - 4.6e-16 58.0 6.8 9.4e-07 28.4 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF3639 PF12341.3 EWM28689.1 - 0.028 14.4 3.6 0.036 14.0 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3639) Glyoxalase_4 PF13669.1 EWM28689.1 - 0.077 13.0 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily WD40 PF00400.27 EWM28690.1 - 3.5e-16 58.3 6.8 8.2e-07 28.6 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF3639 PF12341.3 EWM28690.1 - 0.022 14.7 3.6 0.032 14.2 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3639) Glyoxalase_4 PF13669.1 EWM28690.1 - 0.07 13.1 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MFS_1 PF07690.11 EWM28691.1 - 2.2e-21 75.9 20.7 1.1e-20 73.6 14.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily SPX PF03105.14 EWM28691.1 - 1.6e-19 70.7 1.1 8.8e-19 68.3 0.8 2.1 1 1 0 1 1 1 1 SPX domain Myosin_head PF00063.16 EWM28692.1 - 1.9e-188 627.7 0.0 3.8e-188 626.7 0.0 1.5 1 0 0 1 1 1 1 Myosin head (motor domain) ATP-gua_Ptrans PF00217.14 EWM28692.1 - 1.4e-29 103.1 0.0 3.4e-29 101.8 0.0 1.7 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 EWM28692.1 - 1.6e-09 37.7 0.0 5e-09 36.1 0.0 1.9 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain Myosin_N PF02736.14 EWM28692.1 - 0.012 15.3 0.2 0.027 14.1 0.1 1.6 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain Hydantoinase_B PF02538.9 EWM28693.1 - 1.2e-171 571.5 0.0 1.7e-171 571.0 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EWM28693.1 - 3.4e-89 298.8 1.6 7.1e-89 297.7 1.1 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EWM28693.1 - 8.4e-56 188.2 0.2 1.5e-53 180.8 0.0 2.9 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region G-alpha PF00503.15 EWM28694.1 - 5.6e-107 357.7 3.9 7.3e-107 357.4 2.7 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EWM28694.1 - 9.9e-15 54.2 2.7 5.2e-11 42.0 0.3 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EWM28694.1 - 0.0044 16.1 4.1 0.14 11.2 0.2 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EWM28694.1 - 0.0074 16.7 0.3 1.5 9.3 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 EWM28694.1 - 0.0096 15.4 0.1 0.02 14.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EWM28694.1 - 0.1 12.5 0.2 3.3 7.6 0.1 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase adh_short PF00106.20 EWM28695.1 - 8.9e-29 100.5 0.1 1.2e-28 100.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EWM28695.1 - 2e-12 47.4 0.0 2.8e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EWM28695.1 - 7.1e-12 45.3 0.0 1.3e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EWM28695.1 - 3.8e-06 26.2 0.0 0.00024 20.3 0.0 2.1 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EWM28695.1 - 2.5e-05 24.3 0.0 9e-05 22.5 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EWM28695.1 - 0.0014 18.0 0.2 0.016 14.6 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family SOUL PF04832.7 EWM28696.1 - 4.1e-07 29.7 0.0 9.7e-07 28.4 0.0 1.6 1 1 0 1 1 1 1 SOUL heme-binding protein DUF2358 PF10184.4 EWM28696.1 - 0.015 15.2 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) PP2C PF00481.16 EWM28699.1 - 5.8e-56 189.7 2.2 6.4e-56 189.5 0.1 2.0 2 0 0 2 2 2 1 Protein phosphatase 2C FHA PF00498.21 EWM28699.1 - 2.5e-15 56.3 0.0 6.9e-12 45.3 0.0 3.0 3 0 0 3 3 3 2 FHA domain PP2C_2 PF13672.1 EWM28699.1 - 8.4e-06 25.3 0.0 3e-05 23.5 0.0 1.9 2 1 0 2 2 2 1 Protein phosphatase 2C MT-A70 PF05063.9 EWM28700.1 - 1.6e-53 180.8 0.0 1.9e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 MT-A70 Erythrovirus_X PF06795.6 EWM28701.1 - 0.13 12.3 0.0 0.4 10.7 0.0 1.7 2 0 0 2 2 2 0 Erythrovirus X protein DUF1092 PF06485.6 EWM28702.1 - 7.3e-73 244.8 0.0 9.2e-73 244.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1092) SNARE PF05739.14 EWM28703.1 - 3.5e-14 52.2 3.7 3.5e-14 52.2 2.6 2.5 2 1 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.1 EWM28703.1 - 3.5e-07 30.1 3.3 3.5e-07 30.1 2.3 2.2 2 0 0 2 2 2 1 Syntaxin-like protein Laminin_II PF06009.7 EWM28703.1 - 0.59 9.8 10.3 0.25 11.1 1.1 2.5 2 1 0 2 2 2 0 Laminin Domain II ISG65-75 PF11727.3 EWM28703.1 - 0.82 8.6 6.1 0.62 9.0 0.7 2.1 2 0 0 2 2 2 0 Invariant surface glycoprotein DUF1664 PF07889.7 EWM28703.1 - 8.6 6.1 8.0 8.6 6.1 1.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) IncA PF04156.9 EWM28703.1 - 10 5.6 21.9 8.1 5.9 3.1 2.1 2 0 0 2 2 2 0 IncA protein Peptidase_S10 PF00450.17 EWM28705.1 - 1.2e-101 340.9 0.0 1.8e-101 340.3 0.0 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase Mito_carr PF00153.22 EWM28706.1 - 3.3e-10 39.5 2.1 0.00014 21.5 0.2 2.4 2 0 0 2 2 2 2 Mitochondrial carrier protein HMGL-like PF00682.14 EWM28707.1 - 1.2e-58 198.5 0.1 1.5e-58 198.2 0.0 1.1 1 0 0 1 1 1 1 HMGL-like AdoMetDC_leader PF08132.6 EWM28707.1 - 0.069 13.0 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 S-adenosyl-l-methionine decarboxylase leader peptide Mito_carr PF00153.22 EWM28708.1 - 3.3e-46 154.9 3.2 6.4e-17 61.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Laminin_G_3 PF13385.1 EWM28710.1 - 1e-05 25.8 0.0 2.3e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF1162 PF06650.7 EWM28711.1 - 2.1e-32 112.4 0.0 7.2e-25 87.7 0.0 3.3 3 0 0 3 3 3 3 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EWM28711.1 - 1.5e-27 95.4 0.1 3.2e-27 94.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Integrase_Zn PF02022.14 EWM28711.1 - 1 8.8 0.0 2.9 7.4 0.0 1.8 1 0 0 1 1 1 0 Integrase Zinc binding domain RGP PF03214.8 EWM28711.1 - 3.5 6.2 0.0 6.2 5.4 0.0 1.3 1 0 0 1 1 1 0 Reversibly glycosylated polypeptide DUF693 PF05113.8 EWM28711.1 - 7.9 5.2 0.0 13 4.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF693) Pkinase PF00069.20 EWM28712.1 - 2.1e-46 158.2 0.0 7.6e-46 156.3 0.0 1.8 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM28712.1 - 1.1e-21 77.1 0.0 2.6e-21 75.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EWM28712.1 - 4.5e-05 22.5 0.0 6.8e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EWM28712.1 - 0.00027 20.7 0.0 0.0012 18.6 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family CDC45 PF02724.9 EWM28712.1 - 0.044 11.8 0.3 0.063 11.3 0.2 1.1 1 0 0 1 1 1 0 CDC45-like protein OTU PF02338.14 EWM28713.1 - 2.8e-13 50.5 0.0 4.8e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease UBA PF00627.26 EWM28713.1 - 0.0001 21.9 0.3 0.00035 20.3 0.0 2.1 2 0 0 2 2 2 1 UBA/TS-N domain Ubiquitin_2 PF14560.1 EWM28713.1 - 0.00083 19.5 0.0 0.0015 18.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 EWM28713.1 - 0.016 14.5 0.3 0.052 12.9 0.2 1.8 1 1 0 1 1 1 0 Ubiquitin family Toxin_32 PF08120.6 EWM28713.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 Tamulustoxin family Trypsin_2 PF13365.1 EWM28714.1 - 3.8e-13 49.4 0.0 1.1e-12 47.9 0.0 1.9 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 EWM28714.1 - 1.7e-08 34.1 0.0 8e-08 32.0 0.0 2.0 2 0 0 2 2 2 1 PDZ domain Trypsin PF00089.21 EWM28714.1 - 7.4e-07 28.9 0.0 3.9e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 Trypsin PDZ PF00595.19 EWM28714.1 - 0.051 13.7 0.0 0.41 10.8 0.0 2.3 2 0 0 2 2 2 0 PDZ domain (Also known as DHR or GLGF) Acyltransferase PF01553.16 EWM28715.1 - 9.4e-20 70.3 0.0 1.6e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Ribosomal_L7Ae PF01248.21 EWM28716.1 - 1.1e-23 82.5 2.1 1.5e-23 82.0 1.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1667 PF07892.6 EWM28716.1 - 0.35 10.5 1.8 4.7 6.9 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1667) Polyketide_cyc PF03364.15 EWM28717.1 - 7.8e-07 29.1 0.1 1.5e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 EWM28717.1 - 0.0011 19.1 0.3 0.0021 18.2 0.2 1.5 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport VIT PF08487.5 EWM28717.1 - 0.03 14.0 0.3 0.067 12.8 0.2 1.5 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain Methyltransf_PK PF05891.7 EWM28718.1 - 5.1e-58 195.9 0.0 6.8e-33 113.8 0.0 2.2 2 0 0 2 2 2 2 AdoMet dependent proline di-methyltransferase Methyltransf_2 PF00891.13 EWM28718.1 - 0.0066 15.6 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EWM28718.1 - 0.023 15.2 0.0 0.073 13.6 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain ParA PF10609.4 EWM28719.1 - 1.2e-27 95.5 1.2 4e-27 93.8 0.8 1.9 1 0 0 1 1 1 1 ParA/MinD ATPase like DUF59 PF01883.14 EWM28719.1 - 5.8e-20 71.0 0.6 3.7e-19 68.4 0.2 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF59 CbiA PF01656.18 EWM28719.1 - 1.2e-16 60.7 0.1 1.8e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF971 PF06155.7 EWM28719.1 - 1.6e-12 47.6 0.0 3.2e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) AAA_31 PF13614.1 EWM28719.1 - 1e-09 38.4 0.0 2.9e-09 37.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain MipZ PF09140.6 EWM28719.1 - 1.6e-08 33.9 0.1 2.5e-06 26.7 0.0 2.2 2 0 0 2 2 2 2 ATPase MipZ Fer4_NifH PF00142.13 EWM28719.1 - 0.0004 19.6 0.0 0.0012 18.0 0.0 1.8 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.6 EWM28719.1 - 0.0051 15.9 0.1 0.016 14.2 0.0 1.8 2 0 0 2 2 2 1 VirC1 protein ArsA_ATPase PF02374.10 EWM28719.1 - 0.0093 15.0 1.9 0.082 11.9 0.3 2.4 3 0 0 3 3 3 1 Anion-transporting ATPase YhjQ PF06564.7 EWM28719.1 - 0.014 14.7 0.0 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 YhjQ protein SRP54 PF00448.17 EWM28719.1 - 0.088 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.12 EWM28720.1 - 9.5e-38 130.0 0.1 1.1e-37 129.8 0.1 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GDPD PF03009.12 EWM28722.1 - 1.4e-25 90.3 0.0 5.1e-21 75.3 0.0 2.1 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family OrfB_Zn_ribbon PF07282.6 EWM28723.1 - 2.8e-09 36.4 1.2 5e-09 35.6 0.8 1.4 1 0 0 1 1 1 1 Putative transposase DNA-binding domain GRIM-19 PF06212.7 EWM28724.1 - 1.5e-33 115.2 0.1 1.9e-33 114.9 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein TPR_11 PF13414.1 EWM28725.1 - 1.4e-32 111.1 12.5 1.1e-08 34.5 0.0 6.4 4 1 1 6 6 6 6 TPR repeat TPR_16 PF13432.1 EWM28725.1 - 2.2e-30 104.6 20.1 2.9e-09 37.3 0.2 6.6 4 2 4 8 8 8 7 Tetratricopeptide repeat TPR_14 PF13428.1 EWM28725.1 - 5.9e-29 97.9 26.3 2.1e-05 24.7 0.1 11.1 1 1 10 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 EWM28725.1 - 6.6e-29 97.4 25.2 0.00058 19.5 0.0 11.0 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_17 PF13431.1 EWM28725.1 - 1.1e-26 90.7 5.2 0.04 14.1 0.2 9.7 9 1 1 10 10 10 7 Tetratricopeptide repeat TPR_19 PF14559.1 EWM28725.1 - 3.3e-26 91.4 1.4 2e-07 31.2 0.0 7.0 4 2 3 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.23 EWM28725.1 - 3e-19 67.7 2.9 0.015 14.8 0.0 9.2 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_8 PF13181.1 EWM28725.1 - 1.3e-17 62.1 0.6 0.13 12.1 0.0 10.0 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_12 PF13424.1 EWM28725.1 - 1.7e-17 63.0 23.1 0.0099 15.8 0.1 8.1 2 2 3 6 6 6 5 Tetratricopeptide repeat TPR_15 PF13429.1 EWM28725.1 - 1e-11 44.4 9.9 6.8e-05 22.0 0.0 3.8 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.1 EWM28725.1 - 5.6e-11 42.1 16.3 0.12 12.8 0.0 9.5 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_7 PF13176.1 EWM28725.1 - 2e-09 36.5 17.3 11 6.1 0.0 10.2 9 2 2 11 11 11 0 Tetratricopeptide repeat FAT PF02259.18 EWM28725.1 - 6.4e-06 25.3 4.2 0.0074 15.3 0.2 3.3 2 1 1 3 3 3 2 FAT domain TPR_9 PF13371.1 EWM28725.1 - 0.00032 20.4 10.0 0.3 10.9 0.1 5.6 4 2 2 6 6 6 3 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EWM28725.1 - 0.00061 19.5 0.9 6.2 6.6 0.0 4.8 4 0 0 4 4 4 1 Mad3/BUB1 homology region 1 NARP1 PF12569.3 EWM28725.1 - 0.0029 16.4 0.0 0.27 9.9 0.0 3.2 2 2 1 3 3 3 1 NMDA receptor-regulated protein 1 MIT PF04212.13 EWM28725.1 - 0.0053 16.6 0.9 14 5.6 0.0 5.5 7 0 0 7 7 7 0 MIT (microtubule interacting and transport) domain Suf PF05843.9 EWM28725.1 - 0.043 13.5 0.6 31 4.1 0.0 3.7 2 2 1 3 3 3 0 Suppressor of forked protein (Suf) TPR_4 PF07721.9 EWM28725.1 - 0.045 14.1 12.8 2.1 9.0 0.1 5.3 5 1 1 6 6 3 0 Tetratricopeptide repeat PPR PF01535.15 EWM28725.1 - 0.06 13.3 5.4 5.8 7.1 0.0 5.8 6 0 0 6 6 6 0 PPR repeat HemY_N PF07219.8 EWM28725.1 - 0.16 11.5 0.9 12 5.5 0.0 3.3 3 0 0 3 3 3 0 HemY protein N-terminus SNAP PF14938.1 EWM28725.1 - 0.32 10.0 1.5 1.9 7.5 0.0 2.8 3 1 0 3 3 3 0 Soluble NSF attachment protein, SNAP BTAD PF03704.12 EWM28725.1 - 4.2 7.6 11.9 0.43 10.8 0.1 3.9 4 1 1 5 5 4 0 Bacterial transcriptional activator domain TPR_11 PF13414.1 EWM28726.1 - 9e-28 95.7 11.1 8.4e-09 34.9 0.0 5.5 3 1 1 5 5 5 5 TPR repeat TPR_16 PF13432.1 EWM28726.1 - 2.4e-25 88.5 15.5 2.2e-09 37.7 0.2 5.3 3 1 3 6 6 6 6 Tetratricopeptide repeat TPR_14 PF13428.1 EWM28726.1 - 3.6e-24 83.0 20.4 1.6e-05 25.1 0.1 9.2 1 1 8 9 9 9 7 Tetratricopeptide repeat TPR_17 PF13431.1 EWM28726.1 - 5.6e-24 82.2 5.2 0.03 14.4 0.2 8.3 7 1 1 8 8 8 6 Tetratricopeptide repeat TPR_19 PF14559.1 EWM28726.1 - 2.1e-23 82.4 1.0 1.6e-07 31.5 0.0 6.1 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 EWM28726.1 - 2.5e-22 76.9 17.7 0.00045 19.9 0.0 9.2 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_1 PF00515.23 EWM28726.1 - 1.3e-14 53.1 1.6 0.012 15.2 0.0 7.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.1 EWM28726.1 - 9.7e-14 50.0 0.9 0.099 12.4 0.0 8.3 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_12 PF13424.1 EWM28726.1 - 3.3e-13 49.3 17.8 0.0074 16.1 0.1 6.3 1 1 3 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 EWM28726.1 - 9.2e-09 34.4 11.0 9.4 6.3 0.0 8.5 7 2 2 9 9 9 0 Tetratricopeptide repeat TPR_15 PF13429.1 EWM28726.1 - 9.3e-09 34.7 6.5 0.00026 20.1 2.4 3.5 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_6 PF13174.1 EWM28726.1 - 9.4e-09 35.1 13.9 0.093 13.2 0.0 7.7 9 0 0 9 9 8 2 Tetratricopeptide repeat FAT PF02259.18 EWM28726.1 - 3.1e-06 26.4 3.4 0.0057 15.6 0.2 3.1 2 1 1 3 3 3 2 FAT domain TPR_9 PF13371.1 EWM28726.1 - 7.4e-05 22.5 8.0 0.23 11.3 0.1 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EWM28726.1 - 0.00099 18.8 1.2 4.9 6.9 0.0 4.3 4 1 0 4 4 4 1 Mad3/BUB1 homology region 1 NARP1 PF12569.3 EWM28726.1 - 0.0041 15.9 0.0 0.26 10.0 0.0 2.9 2 1 1 4 4 4 2 NMDA receptor-regulated protein 1 PPR PF01535.15 EWM28726.1 - 0.0093 15.8 0.4 4.5 7.4 0.0 4.6 4 0 0 4 4 4 1 PPR repeat Suf PF05843.9 EWM28726.1 - 0.12 12.1 0.0 44 3.6 0.0 3.2 2 1 1 3 3 3 0 Suppressor of forked protein (Suf) SNAP PF14938.1 EWM28726.1 - 0.22 10.6 0.7 1.4 7.9 0.0 2.4 2 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_4 PF07721.9 EWM28726.1 - 0.52 10.8 11.8 1.6 9.3 0.1 4.4 4 1 1 5 5 3 0 Tetratricopeptide repeat BTAD PF03704.12 EWM28726.1 - 3.3 7.9 12.4 0.32 11.2 0.1 3.8 4 1 1 5 5 4 0 Bacterial transcriptional activator domain Mito_carr PF00153.22 EWM28727.1 - 8.1e-15 54.3 8.2 0.00013 21.5 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Mpv17_PMP22 PF04117.7 EWM28728.1 - 7.3e-22 76.7 0.4 7.3e-22 76.7 0.3 2.0 1 1 1 2 2 2 1 Mpv17 / PMP22 family Gemini_AC4_5_2 PF08464.5 EWM28728.1 - 0.006 16.2 0.8 1.8 8.3 0.1 2.5 2 0 0 2 2 2 2 Geminivirus AC4/5 conserved region DOT1 PF08123.8 EWM28729.1 - 1.1e-11 44.4 0.0 1.6e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 EWM28729.1 - 0.00013 22.5 0.0 0.00018 22.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EWM28729.1 - 0.0016 17.5 0.0 0.0022 17.0 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.15 EWM28729.1 - 0.0091 15.0 0.0 0.012 14.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 EWM28729.1 - 0.013 15.0 0.0 0.022 14.3 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EWM28729.1 - 0.017 15.1 0.0 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EWM28729.1 - 0.065 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EWM28729.1 - 0.094 12.4 0.0 0.2 11.3 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EWM28729.1 - 0.13 12.7 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.8 EWM28730.1 - 1.8e-11 43.7 0.0 3e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 EWM28730.1 - 0.0002 21.9 0.0 0.00029 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EWM28730.1 - 0.0022 17.0 0.0 0.0033 16.4 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.15 EWM28730.1 - 0.014 14.5 0.0 0.018 14.1 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 EWM28730.1 - 0.021 14.3 0.0 0.039 13.5 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EWM28730.1 - 0.025 14.5 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EWM28730.1 - 0.1 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.8 EWM28731.1 - 1.8e-11 43.7 0.0 3e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 EWM28731.1 - 0.0002 21.9 0.0 0.00029 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EWM28731.1 - 0.0022 17.0 0.0 0.0033 16.4 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.15 EWM28731.1 - 0.014 14.5 0.0 0.018 14.1 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 EWM28731.1 - 0.021 14.3 0.0 0.039 13.5 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EWM28731.1 - 0.025 14.5 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EWM28731.1 - 0.1 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.8 EWM28732.1 - 1.8e-11 43.7 0.0 3e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 EWM28732.1 - 0.0002 21.9 0.0 0.00029 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EWM28732.1 - 0.0022 17.0 0.0 0.0033 16.4 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.15 EWM28732.1 - 0.014 14.5 0.0 0.018 14.1 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 EWM28732.1 - 0.021 14.3 0.0 0.039 13.5 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EWM28732.1 - 0.025 14.5 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EWM28732.1 - 0.1 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.8 EWM28733.1 - 1e-11 44.5 0.0 1.5e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 EWM28733.1 - 0.00012 22.6 0.0 0.00017 22.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EWM28733.1 - 0.0015 17.6 0.0 0.0021 17.1 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.15 EWM28733.1 - 0.0086 15.1 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 EWM28733.1 - 0.012 15.1 0.0 0.02 14.4 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EWM28733.1 - 0.016 15.2 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EWM28733.1 - 0.061 13.6 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EWM28733.1 - 0.088 12.5 0.0 0.19 11.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EWM28733.1 - 0.13 12.8 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain SpoU_methylase PF00588.14 EWM28734.1 - 3.6e-09 36.6 0.0 6.5e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family GRIP PF01465.15 EWM28735.1 - 5.9e-12 44.9 0.0 1.3e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 GRIP domain Prefoldin_2 PF01920.15 EWM28735.1 - 0.0018 17.9 2.7 0.0018 17.9 1.9 11.6 9 3 1 11 11 11 3 Prefoldin subunit ATG16 PF08614.6 EWM28735.1 - 0.002 17.9 13.1 0.002 17.9 9.1 7.5 5 2 2 7 7 7 3 Autophagy protein 16 (ATG16) bZIP_2 PF07716.10 EWM28735.1 - 0.16 11.7 0.1 0.16 11.7 0.1 12.7 11 5 6 17 17 17 0 Basic region leucine zipper DUF1322 PF07032.6 EWM28736.1 - 0.059 13.5 0.0 1.1 9.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1322) PPR_2 PF13041.1 EWM28737.1 - 2.6e-50 168.1 0.0 4.6e-10 39.3 0.0 8.8 7 2 1 8 8 8 7 PPR repeat family PPR_1 PF12854.2 EWM28737.1 - 4.1e-35 118.9 9.8 0.0021 17.5 0.0 11.1 11 1 0 11 11 11 9 PPR repeat PPR_3 PF13812.1 EWM28737.1 - 1.4e-32 109.1 24.7 0.00011 22.2 0.0 12.5 12 1 0 12 12 12 7 Pentatricopeptide repeat domain PPR PF01535.15 EWM28737.1 - 5e-29 98.2 19.1 0.00025 20.7 0.0 12.5 14 1 0 14 14 14 7 PPR repeat DUF3368 PF11848.3 EWM28737.1 - 0.045 13.3 0.6 1.7 8.2 0.0 3.7 5 0 0 5 5 5 0 Domain of unknown function (DUF3368) TPR_19 PF14559.1 EWM28737.1 - 3.9 7.8 17.8 1.1 9.6 0.4 4.9 5 1 0 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.20 EWM28738.1 - 2.6e-130 433.1 0.0 2.8e-64 216.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EWM28738.1 - 6.4e-70 235.1 0.0 3.3e-36 124.6 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EWM28738.1 - 3e-15 55.9 0.0 3e-06 26.3 0.0 3.9 4 0 0 4 4 4 2 Kinase-like APH PF01636.18 EWM28738.1 - 5.7e-08 32.7 5.4 0.002 17.8 0.1 3.3 2 1 1 3 3 3 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EWM28738.1 - 0.00041 19.7 0.2 0.7 9.1 0.0 2.9 2 2 0 2 2 2 2 PhoP regulatory network protein YrbL Kdo PF06293.9 EWM28738.1 - 0.00054 19.0 0.0 0.33 10.0 0.0 2.5 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EWM28738.1 - 0.00078 18.8 0.0 2.4 7.4 0.0 3.1 3 0 0 3 3 3 2 RIO1 family ABC1 PF03109.11 EWM28738.1 - 0.003 17.4 0.0 0.07 13.1 0.0 2.4 2 1 0 2 2 2 1 ABC1 family Choline_kinase PF01633.15 EWM28738.1 - 0.0082 15.7 0.0 1.9 8.0 0.0 2.3 2 0 0 2 2 2 2 Choline/ethanolamine kinase YdjO PF14169.1 EWM28738.1 - 0.021 14.2 0.1 0.66 9.4 0.0 2.6 2 0 0 2 2 2 0 Cold-inducible protein YdjO Seadorna_VP7 PF07387.6 EWM28738.1 - 0.084 11.6 0.0 9.8 4.9 0.0 2.2 2 0 0 2 2 2 0 Seadornavirus VP7 Peptidase_S10 PF00450.17 EWM28739.1 - 2.1e-105 353.2 0.0 1.7e-104 350.2 0.0 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase DUF883 PF05957.8 EWM28740.1 - 2.7e-06 27.6 20.9 0.0024 18.2 0.6 4.6 1 1 4 5 5 5 4 Bacterial protein of unknown function (DUF883) MT0933_antitox PF14013.1 EWM28740.1 - 0.00024 21.1 13.2 0.0017 18.4 0.0 4.3 3 2 1 4 4 4 2 MT0933-like antitoxin protein Amidohydro_4 PF13147.1 EWM28740.1 - 0.027 14.4 1.5 0.048 13.7 1.0 1.4 1 0 0 1 1 1 0 Amidohydrolase LEA_4 PF02987.11 EWM28740.1 - 0.14 12.0 24.7 0.4 10.5 0.8 6.6 6 1 1 7 7 7 0 Late embryogenesis abundant protein Apolipoprotein PF01442.13 EWM28740.1 - 0.17 11.3 10.0 0.35 10.3 5.8 2.0 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain ClpS PF02617.12 EWM28740.1 - 0.72 9.6 7.4 4.9 6.9 0.4 3.7 2 1 2 4 4 4 0 ATP-dependent Clp protease adaptor protein ClpS YtxH PF12732.2 EWM28740.1 - 1.1 9.6 26.6 1.5e+04 -10.9 18.3 4.9 1 1 0 1 1 1 0 YtxH-like protein ATP-synt_B PF00430.13 EWM28740.1 - 2.1 8.1 22.7 0.67 9.7 5.4 3.6 1 1 2 3 3 3 0 ATP synthase B/B' CF(0) HisKA_3 PF07730.8 EWM28740.1 - 2.2 8.6 9.0 1e+02 3.3 0.0 4.6 3 2 1 4 4 4 0 Histidine kinase DUF2229 PF09989.4 EWM28740.1 - 2.9 7.3 8.0 0.58 9.5 2.3 2.2 1 1 2 3 3 3 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF883 PF05957.8 EWM28741.1 - 4.6e-07 30.1 21.7 0.0021 18.3 0.6 4.7 1 1 4 5 5 5 3 Bacterial protein of unknown function (DUF883) MT0933_antitox PF14013.1 EWM28741.1 - 0.00017 21.6 16.1 0.0016 18.5 0.0 4.8 3 3 1 4 4 4 2 MT0933-like antitoxin protein LEA_4 PF02987.11 EWM28741.1 - 0.018 14.9 26.1 0.38 10.6 0.8 6.7 6 1 1 7 7 7 0 Late embryogenesis abundant protein Amidohydro_4 PF13147.1 EWM28741.1 - 0.026 14.5 1.5 0.044 13.8 1.0 1.3 1 0 0 1 1 1 0 Amidohydrolase YtxH PF12732.2 EWM28741.1 - 0.6 10.5 28.5 1.5e+04 -12.9 19.8 5.1 1 1 0 1 1 0 0 YtxH-like protein MMR1 PF08505.5 EWM28741.1 - 0.65 9.9 6.1 0.92 9.5 4.2 1.4 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein HisKA_3 PF07730.8 EWM28741.1 - 0.67 10.3 9.3 63 4.0 0.0 4.6 3 2 1 4 4 4 0 Histidine kinase ClpS PF02617.12 EWM28741.1 - 0.69 9.6 7.6 4.5 7.0 0.4 3.7 2 1 1 4 4 4 0 ATP-dependent Clp protease adaptor protein ClpS ATP-synt_B PF00430.13 EWM28741.1 - 1.5 8.6 23.8 0.6 9.9 5.4 3.8 1 1 1 3 3 3 0 ATP synthase B/B' CF(0) Apolipoprotein PF01442.13 EWM28741.1 - 2.4 7.6 16.0 1 8.8 6.9 2.6 1 1 2 3 3 3 0 Apolipoprotein A1/A4/E domain DUF2229 PF09989.4 EWM28741.1 - 2.4 7.5 8.1 0.73 9.2 2.7 2.3 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) ketoacyl-synt PF00109.21 EWM28742.1 - 1.2e-51 175.6 2.1 1.2e-51 175.6 1.4 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EWM28742.1 - 2.4e-34 117.7 2.0 4.6e-34 116.8 1.4 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EWM28742.1 - 4.7e-05 22.4 0.1 9.9e-05 21.4 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EWM28742.1 - 0.00029 20.4 0.5 0.14 11.8 0.3 2.7 3 0 0 3 3 3 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Peptidase_M22 PF00814.20 EWM28743.1 - 6.8e-84 281.5 0.0 8.4e-84 281.2 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family UCR_14kD PF02271.11 EWM28744.1 - 1.3e-21 76.3 0.3 1.6e-21 76.0 0.2 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit MIF4G PF02854.14 EWM28745.1 - 7.6e-41 139.8 0.3 1e-27 96.9 0.3 2.3 2 0 0 2 2 2 2 MIF4G domain MA3 PF02847.12 EWM28745.1 - 3.9e-05 23.3 0.1 0.00011 21.9 0.0 1.8 1 0 0 1 1 1 1 MA3 domain Topo-VIb_trans PF09239.6 EWM28746.1 - 1.4e-50 170.9 0.0 3.1e-50 169.8 0.0 1.6 1 0 0 1 1 1 1 Topoisomerase VI B subunit, transducer HATPase_c_3 PF13589.1 EWM28746.1 - 5.8e-09 35.7 0.0 2.8e-06 27.0 0.0 2.4 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EWM28746.1 - 1.2e-08 34.5 0.0 2.6e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1162 PF06650.7 EWM28747.1 - 3.1e-26 92.1 0.0 1.2e-18 67.3 0.0 3.8 4 1 0 4 4 4 2 Protein of unknown function (DUF1162) C2 PF00168.25 EWM28747.1 - 1.5e-19 69.5 0.3 4.1e-16 58.5 0.1 2.9 2 0 0 2 2 2 2 C2 domain Chorein_N PF12624.2 EWM28747.1 - 9.1e-19 67.1 0.0 2.3e-18 65.8 0.0 1.7 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter PDZ PF00595.19 EWM28747.1 - 0.023 14.8 0.0 0.065 13.4 0.0 1.8 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EWM28747.1 - 0.064 13.1 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 PDZ domain TPT PF03151.11 EWM28748.1 - 1.4e-11 44.2 10.9 1.4e-11 44.2 7.5 1.8 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EWM28748.1 - 1.6e-06 27.3 14.1 1.6e-06 27.3 9.8 1.7 2 0 0 2 2 2 1 UAA transporter family PIF1 PF05970.9 EWM28750.1 - 1.2e-53 182.4 0.0 2.9e-38 131.7 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EWM28750.1 - 8.5e-14 51.5 0.0 3.9e-13 49.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EWM28750.1 - 5.2e-05 23.3 0.0 0.00012 22.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EWM28750.1 - 0.00022 21.3 0.0 0.00063 19.8 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.1 EWM28750.1 - 0.00033 20.6 0.0 0.0013 18.7 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 EWM28750.1 - 0.00061 19.2 0.1 0.44 9.9 0.0 2.4 1 1 1 2 2 2 2 IstB-like ATP binding protein Herpes_Helicase PF02689.9 EWM28750.1 - 0.00099 16.9 0.1 0.2 9.3 0.0 2.1 2 0 0 2 2 2 2 Helicase T2SE PF00437.15 EWM28750.1 - 0.0019 17.1 0.1 0.003 16.4 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 EWM28750.1 - 0.011 15.4 0.5 0.03 14.0 0.3 1.7 1 0 0 1 1 1 0 Part of AAA domain Viral_helicase1 PF01443.13 EWM28750.1 - 0.018 14.5 0.0 0.24 10.8 0.1 2.6 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 EWM28750.1 - 0.044 13.2 0.0 2.7 7.4 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase NACHT PF05729.7 EWM28750.1 - 0.047 13.3 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.11 EWM28750.1 - 0.048 12.9 0.4 0.29 10.3 0.0 2.2 1 1 1 2 2 2 0 PhoH-like protein AAA PF00004.24 EWM28750.1 - 0.074 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1077 PF06417.7 EWM28752.1 - 6e-35 119.3 1.5 7.9e-35 118.9 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) PAS_7 PF12860.2 EWM28752.1 - 0.1 12.6 0.2 2.4 8.2 0.0 2.1 2 0 0 2 2 2 0 PAS fold tRNA-synt_1d PF00750.14 EWM28753.1 - 1.8e-100 336.1 0.0 2.5e-100 335.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EWM28753.1 - 8.3e-21 74.1 1.9 1.2e-19 70.4 0.1 2.4 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 EWM28753.1 - 4.7e-14 52.6 0.0 1.2e-13 51.4 0.0 1.7 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.14 EWM28753.1 - 0.0051 15.9 0.0 0.0078 15.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EWM28753.1 - 0.082 11.5 0.1 0.18 10.4 0.0 1.5 2 0 0 2 2 2 0 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EWM28753.1 - 0.1 10.5 0.0 0.17 9.8 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) WD40 PF00400.27 EWM28754.1 - 1.2e-41 139.1 27.7 1.6e-09 37.2 0.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat FAD_binding_7 PF03441.9 EWM28754.1 - 3.2e-34 118.4 4.9 1.1e-33 116.6 3.4 1.8 1 1 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EWM28754.1 - 1.1e-13 51.2 0.1 2.4e-13 50.1 0.1 1.6 1 0 0 1 1 1 1 DNA photolyase Usp PF00582.21 EWM28754.1 - 3.6 7.7 6.5 0.39 10.9 0.2 2.6 3 0 0 3 3 3 0 Universal stress protein family CBFB_NFYA PF02045.10 EWM28755.1 - 2.1e-26 92.1 4.8 3.9e-26 91.3 3.3 1.4 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B adh_short_C2 PF13561.1 EWM28756.1 - 1.4e-33 116.6 0.2 1.9e-33 116.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EWM28756.1 - 1.1e-22 80.7 5.1 1.1e-22 80.7 3.5 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EWM28756.1 - 1.6e-09 37.6 1.5 1.6e-09 37.6 1.1 1.7 2 0 0 2 2 2 1 KR domain SEF14_adhesin PF06443.6 EWM28756.1 - 0.013 15.1 0.8 0.028 14.0 0.4 1.7 1 1 0 1 1 1 0 SEF14-like adhesin NAD_binding_10 PF13460.1 EWM28756.1 - 0.013 15.5 1.0 0.028 14.4 0.7 1.6 1 1 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 EWM28756.1 - 0.017 14.5 0.3 0.027 13.8 0.2 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.1 EWM28756.1 - 0.051 13.9 0.0 0.13 12.6 0.0 1.7 1 1 1 2 2 2 0 Methyltransferase domain Polysacc_synt_2 PF02719.10 EWM28756.1 - 0.056 12.3 0.1 0.077 11.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DAGK_cat PF00781.19 EWM28757.1 - 1.4e-22 79.5 0.0 2.6e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Cofilin_ADF PF00241.15 EWM28758.1 - 2.8e-16 59.5 0.0 1.8e-08 34.3 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein M20_dimer PF07687.9 EWM28759.1 - 8.9e-20 70.5 0.0 1.4e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 EWM28759.1 - 7.2e-05 22.3 0.1 0.00011 21.7 0.1 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 zf-C2H2 PF00096.21 EWM28760.1 - 0.00024 21.2 5.3 0.054 13.8 0.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EWM28760.1 - 0.054 13.8 8.4 0.078 13.2 0.2 3.1 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.1 EWM28760.1 - 0.093 13.1 7.7 2 8.9 0.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Inositol_P PF00459.20 EWM28761.1 - 3.8e-48 164.1 0.2 8.3e-48 163.0 0.1 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family Dysbindin PF04440.11 EWM28762.1 - 8.4 6.1 10.5 9.3 5.9 0.0 3.3 3 0 0 3 3 3 0 Dysbindin (Dystrobrevin binding protein 1) PPR_2 PF13041.1 EWM28763.1 - 3.1e-20 71.8 0.0 9e-07 28.7 0.0 4.2 2 1 2 4 4 4 4 PPR repeat family PPR PF01535.15 EWM28763.1 - 3.5e-20 70.5 1.4 9.8e-06 25.2 0.0 4.9 5 0 0 5 5 5 4 PPR repeat PPR_1 PF12854.2 EWM28763.1 - 2.7e-16 58.7 0.2 0.00059 19.2 0.0 4.6 4 0 0 4 4 4 4 PPR repeat PPR_3 PF13812.1 EWM28763.1 - 1.1e-14 53.4 0.0 0.0032 17.6 0.0 5.1 5 0 0 5 5 5 4 Pentatricopeptide repeat domain TPR_11 PF13414.1 EWM28765.1 - 5.1e-19 67.6 13.0 2.9e-11 42.8 1.8 3.0 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EWM28765.1 - 3.1e-15 55.0 13.4 9.4e-06 25.0 0.4 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EWM28765.1 - 3.6e-12 45.2 13.1 4.7e-05 22.9 0.7 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EWM28765.1 - 9.4e-08 32.5 7.5 0.00033 21.2 3.3 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EWM28765.1 - 4.2e-06 26.1 6.3 0.001 18.6 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EWM28765.1 - 0.0004 20.2 9.2 0.027 14.3 2.5 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EWM28765.1 - 0.00086 19.7 6.9 0.028 15.0 1.3 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EWM28765.1 - 0.0078 16.5 6.6 0.12 12.7 1.9 3.1 1 1 1 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.12 EWM28765.1 - 0.0098 16.2 7.1 0.11 12.8 0.3 3.6 3 1 1 4 4 4 1 Bacterial transcriptional activator domain TPR_9 PF13371.1 EWM28765.1 - 0.012 15.4 3.3 0.14 12.0 2.2 2.7 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.1 EWM28765.1 - 0.012 15.7 6.2 0.13 12.5 0.6 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EWM28765.1 - 0.31 11.5 9.0 0.74 10.4 0.5 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF525 PF04379.9 EWM28767.1 - 5e-07 29.5 0.0 1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF525) Zip PF02535.17 EWM28768.1 - 3e-42 144.7 24.7 3.8e-41 141.1 17.1 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter V-SNARE PF05008.10 EWM28769.1 - 3.3e-10 39.9 0.1 3.3e-10 39.9 0.0 2.4 3 1 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 EWM28769.1 - 1.1e-09 38.2 3.6 1.1e-09 38.2 2.5 2.1 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EWM28769.1 - 0.00024 20.7 0.8 0.0015 18.1 0.0 2.5 2 2 1 3 3 3 1 Sec20 Laminin_II PF06009.7 EWM28769.1 - 0.056 13.1 3.5 0.32 10.7 0.7 2.2 2 0 0 2 2 2 0 Laminin Domain II SlyX PF04102.7 EWM28769.1 - 0.2 12.0 4.0 0.94 9.8 0.4 2.7 2 0 0 2 2 2 0 SlyX zf-ZPR1 PF03367.8 EWM28769.1 - 0.36 9.9 2.2 2.5 7.2 0.1 2.4 2 1 0 2 2 2 0 ZPR1 zinc-finger domain DUF1664 PF07889.7 EWM28769.1 - 0.39 10.5 2.3 8.7 6.1 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PspA_IM30 PF04012.7 EWM28769.1 - 0.48 9.7 7.1 0.23 10.7 0.3 2.4 2 2 0 2 2 2 0 PspA/IM30 family DUF641 PF04859.7 EWM28769.1 - 0.55 9.9 3.1 5.5 6.7 0.1 2.6 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) V-SNARE PF05008.10 EWM28770.1 - 2.6e-10 40.3 2.3 2.7e-10 40.2 0.0 2.2 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 EWM28770.1 - 7.4e-07 29.1 1.8 7.4e-07 29.1 1.2 2.2 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Vps53_N PF04100.7 EWM28770.1 - 0.0075 15.0 2.9 1.2 7.8 1.2 2.1 2 0 0 2 2 2 2 Vps53-like, N-terminal Tropomyosin PF00261.15 EWM28770.1 - 0.085 11.9 7.3 1.2 8.1 0.7 2.2 2 0 0 2 2 2 0 Tropomyosin Laminin_II PF06009.7 EWM28770.1 - 0.12 12.1 1.5 1.6 8.4 0.2 2.3 2 0 0 2 2 2 0 Laminin Domain II PspA_IM30 PF04012.7 EWM28770.1 - 0.13 11.6 5.5 0.18 11.1 0.3 2.4 2 1 0 2 2 2 0 PspA/IM30 family Spc7 PF08317.6 EWM28770.1 - 0.41 9.2 3.0 0.56 8.8 2.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF641 PF04859.7 EWM28770.1 - 0.42 10.3 4.5 5 6.8 0.1 2.6 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) FliJ PF02050.11 EWM28770.1 - 0.92 9.5 5.5 3.4 7.7 0.6 2.6 2 1 0 2 2 2 0 Flagellar FliJ protein Lebercilin PF15619.1 EWM28770.1 - 1 8.7 6.3 9.4 5.5 4.4 2.1 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Atg14 PF10186.4 EWM28770.1 - 3.8 6.3 6.8 1.5 7.7 0.6 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 SlyX PF04102.7 EWM28770.1 - 5.4 7.4 9.9 0.49 10.7 0.6 2.7 3 0 0 3 3 3 0 SlyX MPP6 PF10175.4 EWM28771.1 - 8.1e-06 26.1 8.1 0.0012 19.1 0.3 2.2 1 1 1 2 2 2 2 M-phase phosphoprotein 6 Rrn6 PF10214.4 EWM28771.1 - 0.14 10.1 7.3 0.17 9.9 5.0 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Ly49 PF08391.5 EWM28772.1 - 0.26 11.4 0.6 1.5 8.9 0.6 1.9 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region polyprenyl_synt PF00348.12 EWM28774.1 - 1.1e-82 276.7 0.1 1.5e-82 276.3 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Myf5 PF12232.3 EWM28774.1 - 1.8 9.2 5.5 4.4 7.9 3.8 1.7 1 0 0 1 1 1 0 Myogenic determination factor 5 polyprenyl_synt PF00348.12 EWM28775.1 - 7e-83 277.4 0.1 9.1e-83 277.0 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase FA_desaturase PF00487.19 EWM28776.1 - 1.5e-25 90.1 14.6 1.5e-25 90.1 10.1 2.1 1 1 1 2 2 2 2 Fatty acid desaturase BolA PF01722.13 EWM28777.1 - 1.2e-17 63.6 0.0 1.7e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein PLU-1 PF08429.6 EWM28778.1 - 7.1e-63 212.5 46.1 1.2e-29 103.3 2.6 6.9 5 1 2 7 7 7 7 PLU-1-like protein PHD PF00628.24 EWM28778.1 - 3.3e-14 52.2 28.2 9.8e-08 31.5 5.3 2.6 2 0 0 2 2 2 2 PHD-finger ELM2 PF01448.19 EWM28778.1 - 0.0005 20.6 0.0 0.0013 19.3 0.0 1.7 1 0 0 1 1 1 1 ELM2 domain C1_1 PF00130.17 EWM28778.1 - 0.0034 17.0 4.6 0.0034 17.0 3.2 3.6 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 EWM28778.1 - 1.1 8.6 16.2 0.062 12.6 3.0 2.6 2 0 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.1 EWM28778.1 - 1.4 8.7 16.2 0.13 12.0 3.9 2.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF1157 PF06636.6 EWM28778.1 - 2.3 6.7 0.0 3.5 6.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1157) GidB PF02527.10 EWM28780.1 - 1.1e-31 109.3 0.0 1.6e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.1 EWM28780.1 - 1.7e-07 30.9 0.0 2.5e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EWM28780.1 - 0.016 14.6 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain FUN14 PF04930.10 EWM28781.1 - 6e-13 48.9 0.0 1.2e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 FUN14 family tRNA_m1G_MT PF01746.16 EWM28782.1 - 2.1e-34 118.7 0.0 3e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase TruB_N PF01509.13 EWM28783.1 - 7.3e-46 156.0 0.0 9.8e-46 155.6 0.0 1.2 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) HECT PF00632.20 EWM28785.1 - 2.2e-73 247.2 0.0 2.7e-73 246.8 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ig_2 PF13895.1 EWM28785.1 - 0.093 12.8 0.0 0.42 10.7 0.0 2.1 2 0 0 2 2 2 0 Immunoglobulin domain DAD PF02109.11 EWM28787.1 - 5.7e-35 119.7 4.5 7.2e-35 119.4 3.1 1.1 1 0 0 1 1 1 1 DAD family ABC2_membrane_3 PF12698.2 EWM28787.1 - 0.082 11.9 4.2 0.093 11.7 2.9 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein CAAD PF14159.1 EWM28787.1 - 0.17 11.5 0.8 0.19 11.3 0.3 1.4 1 1 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase MNHE PF01899.11 EWM28787.1 - 0.26 10.9 1.4 0.31 10.6 0.6 1.4 1 1 0 1 1 1 0 Na+/H+ ion antiporter subunit zf-Sec23_Sec24 PF04810.10 EWM28788.1 - 0.033 13.7 9.8 0.45 10.1 0.7 4.0 2 1 2 4 4 4 0 Sec23/Sec24 zinc finger DZR PF12773.2 EWM28788.1 - 3.2 7.6 7.9 7.7 6.4 2.4 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-RanBP PF00641.13 EWM28788.1 - 6 6.0 12.9 1.1 8.3 0.8 3.3 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others V-SNARE_C PF12352.3 EWM28789.1 - 8.5e-08 32.1 1.9 8.5e-08 32.1 1.4 1.8 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.10 EWM28789.1 - 2.4e-06 27.6 0.4 2.4e-06 27.6 0.3 2.3 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Synaptobrevin PF00957.16 EWM28789.1 - 2.9e-05 23.6 1.1 2.9e-05 23.6 0.8 1.9 1 1 0 1 1 1 1 Synaptobrevin Sec20 PF03908.8 EWM28789.1 - 0.0087 15.7 0.5 0.029 14.0 0.2 1.9 1 1 0 1 1 1 1 Sec20 HpaB_N PF11794.3 EWM28789.1 - 0.029 13.7 0.9 0.039 13.3 0.6 1.2 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Laminin_II PF06009.7 EWM28789.1 - 0.058 13.1 3.6 0.15 11.8 1.5 2.0 1 1 1 2 2 2 0 Laminin Domain II ATP-grasp_4 PF13535.1 EWM28790.1 - 4.4e-23 81.9 0.1 6.2e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EWM28790.1 - 2.6e-06 27.3 0.0 4.9e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 EWM28790.1 - 6.7e-06 25.8 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_Ter PF15632.1 EWM28790.1 - 0.0001 21.1 0.0 0.0035 16.1 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 EWM28791.1 - 4.4e-23 81.9 0.1 6.2e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EWM28791.1 - 2.6e-06 27.3 0.0 4.9e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 EWM28791.1 - 6.7e-06 25.8 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_Ter PF15632.1 EWM28791.1 - 0.0001 21.1 0.0 0.0035 16.1 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Mob_synth_C PF06463.8 EWM28792.1 - 1.5e-32 111.9 0.0 2.7e-32 111.1 0.0 1.4 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 EWM28792.1 - 7.9e-25 87.9 0.0 1.2e-24 87.3 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 EWM28792.1 - 8.8e-07 28.9 0.0 1.6e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 EWM28792.1 - 1e-06 28.9 0.0 1.7e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain DUF566 PF04484.7 EWM28792.1 - 2.2 7.7 6.2 3.1 7.2 4.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) VHS PF00790.14 EWM28793.1 - 4.9e-24 84.5 0.0 7.3e-24 83.9 0.0 1.3 1 0 0 1 1 1 1 VHS domain ADK PF00406.17 EWM28794.1 - 5.5e-46 156.1 0.0 6.6e-46 155.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EWM28794.1 - 4.1e-13 48.7 0.0 6.4e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 EWM28794.1 - 8.7e-08 33.0 0.0 2.2e-07 31.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EWM28794.1 - 5.7e-05 23.4 0.2 0.00067 19.9 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EWM28794.1 - 7.2e-05 22.6 0.1 0.00092 19.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EWM28794.1 - 0.053 12.6 0.0 0.092 11.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.24 EWM28794.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) HIT PF01230.18 EWM28795.1 - 3.9e-19 69.0 0.0 6.9e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EWM28795.1 - 1.2e-11 44.8 0.0 2.2e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EWM28795.1 - 0.04 13.5 0.0 0.07 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 PX PF00787.19 EWM28796.1 - 2.3e-12 46.6 1.3 3.6e-12 46.0 0.9 1.2 1 0 0 1 1 1 1 PX domain Erg28 PF03694.8 EWM28797.1 - 1.1e-25 89.7 4.4 1.9e-25 89.0 3.0 1.3 1 0 0 1 1 1 1 Erg28 like protein DUF3325 PF11804.3 EWM28797.1 - 0.0037 17.1 0.3 0.0037 17.1 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3325) ELF PF03317.8 EWM28797.1 - 0.058 12.6 0.5 0.071 12.3 0.3 1.1 1 0 0 1 1 1 0 ELF protein DUF1467 PF07330.7 EWM28797.1 - 1.6 8.5 8.4 11 5.9 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1467) ERGIC_N PF13850.1 EWM28797.1 - 3.6 7.6 6.0 0.57 10.1 0.3 2.3 2 1 1 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) E1-E2_ATPase PF00122.15 EWM28798.1 - 9.4e-14 51.0 0.1 1.5e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 E1-E2 ATPase DUF1279 PF06916.8 EWM28799.1 - 4e-13 49.4 1.4 1.4e-12 47.7 1.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) HSP20 PF00011.16 EWM28800.1 - 1.7e-24 85.5 2.0 2.1e-24 85.3 1.4 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF4097 PF13349.1 EWM28800.1 - 0.0014 18.2 0.1 0.0017 17.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4097) DUF2807 PF10988.3 EWM28800.1 - 0.067 12.7 1.0 0.65 9.5 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2807) Aldose_epim PF01263.15 EWM28801.1 - 1.3e-26 93.4 0.1 2.1e-26 92.7 0.1 1.4 1 1 0 1 1 1 1 Aldose 1-epimerase ABC1 PF03109.11 EWM28802.1 - 1.6e-17 63.5 0.0 7e-14 51.8 0.0 2.6 2 0 0 2 2 2 2 ABC1 family RIO1 PF01163.17 EWM28802.1 - 3.3e-05 23.3 0.0 7.9e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.20 EWM28802.1 - 8.5e-05 21.8 0.0 0.00082 18.5 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.18 EWM28802.1 - 9.3e-05 22.2 0.0 0.00038 20.2 0.0 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EWM28802.1 - 0.0051 15.9 0.0 0.082 11.9 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase Choline_kinase PF01633.15 EWM28802.1 - 0.082 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.20 EWM28803.1 - 2.9e-65 220.0 0.0 3.7e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM28803.1 - 2.7e-31 108.6 0.0 3.5e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EWM28803.1 - 3.1e-05 23.1 0.1 5.4e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EWM28803.1 - 0.00013 21.0 0.0 0.00024 20.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EWM28803.1 - 0.03 14.0 0.1 0.71 9.5 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF4131 PF13567.1 EWM28804.1 - 0.087 12.2 0.6 0.21 10.9 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) GST_N PF02798.15 EWM28805.1 - 2.1e-11 43.8 0.0 3.6e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EWM28805.1 - 8.3e-09 35.2 0.1 6.3e-08 32.3 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EWM28805.1 - 1e-07 32.0 0.0 2.2e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EWM28805.1 - 4.1e-06 26.7 0.0 7.4e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EWM28805.1 - 2.8e-05 24.0 0.0 4.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3317 PF11779.3 EWM28806.1 - 6.4e-09 35.1 2.3 9.3e-09 34.5 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) Vma12 PF11712.3 EWM28806.1 - 0.087 12.5 0.1 0.12 12.0 0.1 1.1 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase dCMP_cyt_deam_1 PF00383.17 EWM28807.1 - 1.2e-19 69.8 0.0 1.9e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EWM28807.1 - 0.001 18.7 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 APOBEC-like N-terminal domain Nitro_FeMo-Co PF02579.12 EWM28807.1 - 0.014 15.4 0.4 0.31 11.1 0.1 2.6 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor DEAD PF00270.24 EWM28808.1 - 9e-15 54.5 0.0 3.1e-14 52.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EWM28808.1 - 1.7e-10 41.0 0.0 5.1e-09 36.2 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SE PF00437.15 EWM28808.1 - 0.12 11.2 0.0 0.24 10.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.1 EWM28808.1 - 2.2 8.4 4.9 7.5 6.7 0.0 4.0 4 2 1 5 5 5 0 AAA domain DUF1749 PF08538.5 EWM28809.1 - 4.6e-34 117.6 0.0 5.6e-34 117.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 EWM28809.1 - 8.5e-09 35.6 0.1 1.1e-08 35.2 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM28809.1 - 0.005 16.6 0.0 0.0092 15.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family CTP_transf_1 PF01148.15 EWM28810.1 - 1.5e-06 28.0 8.1 3e-06 27.1 5.6 1.5 1 1 0 1 1 1 1 Cytidylyltransferase family NYN_YacP PF05991.6 EWM28811.1 - 2e-27 95.9 0.2 2e-27 95.9 0.1 2.0 3 0 0 3 3 3 1 YacP-like NYN domain DUF1378 PF07125.6 EWM28811.1 - 0.071 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) Methyltransf_4 PF02390.12 EWM28812.1 - 2.3e-36 124.6 0.0 3e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EWM28812.1 - 0.00018 22.0 0.0 0.00034 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM28812.1 - 0.0023 17.5 0.0 0.0042 16.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EWM28812.1 - 0.022 14.1 0.0 0.063 12.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain Reo_sigmaC PF04582.7 EWM28815.1 - 0.0051 16.0 8.9 0.36 9.9 0.6 2.5 1 1 0 2 2 2 2 Reovirus sigma C capsid protein DUF1664 PF07889.7 EWM28815.1 - 0.095 12.5 19.9 0.037 13.8 3.3 3.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DNA_pol_A_exo1 PF01612.15 EWM28817.1 - 5.7e-41 139.9 0.2 1.1e-40 139.0 0.2 1.4 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.18 EWM28817.1 - 1e-13 50.7 0.0 1.5e-12 47.0 0.0 2.6 2 0 0 2 2 2 1 HRDC domain PMC2NT PF08066.7 EWM28817.1 - 0.0026 18.0 0.0 0.0065 16.7 0.0 1.7 1 0 0 1 1 1 1 PMC2NT (NUC016) domain CorA PF01544.13 EWM28817.1 - 0.12 11.3 0.5 0.44 9.5 0.1 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Bromo_TP PF07524.8 EWM28818.1 - 3.9e-11 42.5 0.2 5.8e-11 41.9 0.1 1.2 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.4 EWM28818.1 - 5.5e-07 29.5 0.2 5.5e-07 29.5 0.1 2.1 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Apolipoprotein PF01442.13 EWM28819.1 - 0.0019 17.7 0.1 0.003 17.1 0.1 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain PRA1 PF03208.14 EWM28820.1 - 5.3e-24 84.2 0.4 8.4e-24 83.6 0.3 1.2 1 0 0 1 1 1 1 PRA1 family protein Neurensin PF14927.1 EWM28820.1 - 0.0053 16.1 0.6 0.0093 15.3 0.4 1.4 1 0 0 1 1 1 1 Neurensin PQ-loop PF04193.9 EWM28820.1 - 0.41 10.2 4.5 0.51 9.9 1.8 2.2 2 1 0 2 2 2 0 PQ loop repeat DUF2178 PF09946.4 EWM28820.1 - 1.2 8.8 5.2 0.3 10.8 0.8 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2178) CAP_GLY PF01302.20 EWM28822.1 - 2e-21 75.4 0.5 3e-21 74.8 0.3 1.3 1 0 0 1 1 1 1 CAP-Gly domain RNA_pol_Rpb1_5 PF04998.12 EWM28823.1 - 8.3e-87 290.9 0.0 1.2e-86 290.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_3 PF04983.13 EWM28823.1 - 6.4e-32 110.4 0.0 1e-31 109.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EWM28823.1 - 3.9e-20 71.5 0.0 1.2e-19 70.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_2 PF00623.15 EWM28823.1 - 3e-18 66.3 0.1 6.1e-18 65.3 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 Daxx PF03344.10 EWM28823.1 - 1.5 7.2 9.6 2.3 6.6 6.6 1.1 1 0 0 1 1 1 0 Daxx Family DUF4064 PF13273.1 EWM28824.1 - 0.18 11.9 0.0 0.18 11.9 0.0 3.9 4 1 1 5 5 5 0 Protein of unknown function (DUF4064) DUF1974 PF09317.6 EWM28825.1 - 6.6e-58 196.3 0.1 2e-57 194.7 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1974) Acyl-CoA_dh_N PF02771.11 EWM28825.1 - 5.1e-18 65.7 0.0 1.9e-17 63.8 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 EWM28825.1 - 3.9e-14 52.9 1.3 9.1e-14 51.8 0.9 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EWM28825.1 - 0.014 14.9 0.0 0.058 12.9 0.0 2.1 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, middle domain DUF1974 PF09317.6 EWM28826.1 - 6.6e-58 196.3 0.1 2e-57 194.7 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1974) Acyl-CoA_dh_N PF02771.11 EWM28826.1 - 5.1e-18 65.7 0.0 1.9e-17 63.8 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 EWM28826.1 - 3.9e-14 52.9 1.3 9.1e-14 51.8 0.9 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EWM28826.1 - 0.014 14.9 0.0 0.058 12.9 0.0 2.1 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, middle domain Chorein_N PF12624.2 EWM28827.1 - 1.1e-06 28.1 0.0 3e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Aminotran_3 PF00202.16 EWM28828.1 - 3.9e-95 318.5 0.0 4.6e-95 318.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 EWM28828.1 - 0.019 14.0 0.0 0.036 13.2 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase RmlD_sub_bind PF04321.12 EWM28830.1 - 2.9e-19 69.0 0.0 1.3e-18 66.8 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EWM28830.1 - 2.1e-15 56.7 0.0 4.2e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EWM28830.1 - 3.5e-05 22.8 0.0 6.8e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EWM28830.1 - 9.5e-05 21.2 0.1 0.00045 18.9 0.1 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EWM28830.1 - 0.0004 19.3 0.0 0.00069 18.6 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EWM28830.1 - 0.004 17.0 0.0 0.0078 16.1 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EWM28830.1 - 0.054 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 KR domain PP2C PF00481.16 EWM28831.1 - 1.3e-67 227.9 0.0 1.6e-67 227.5 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EWM28831.1 - 2.3e-06 27.1 0.1 3.8e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 EWM28832.1 - 1.3e-67 227.9 0.0 1.6e-67 227.5 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EWM28832.1 - 2.3e-06 27.1 0.1 3.8e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Redoxin PF08534.5 EWM28833.1 - 2e-29 102.0 0.0 2.3e-29 101.8 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EWM28833.1 - 1e-10 41.3 0.0 1.2e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family CHASE2 PF05226.6 EWM28833.1 - 0.0095 15.1 0.0 0.012 14.8 0.0 1.1 1 0 0 1 1 1 1 CHASE2 domain MMR_HSR1 PF01926.18 EWM28834.1 - 5.2e-20 71.5 0.0 1e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EWM28834.1 - 1.6e-10 40.4 0.0 3.3e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EWM28834.1 - 2.2e-06 27.5 0.0 0.017 14.9 0.0 2.4 2 0 0 2 2 2 2 Dynamin family AIG1 PF04548.11 EWM28834.1 - 0.0011 18.1 0.0 0.0016 17.5 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 EWM28834.1 - 0.0062 17.0 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 EWM28834.1 - 0.012 15.5 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Resolvase PF00239.16 EWM28834.1 - 0.022 14.5 0.0 0.052 13.4 0.0 1.6 1 0 0 1 1 1 0 Resolvase, N terminal domain AAA_28 PF13521.1 EWM28834.1 - 0.04 13.8 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF3006 PF11213.3 EWM28834.1 - 0.043 13.5 0.5 0.25 11.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) DUF258 PF03193.11 EWM28834.1 - 0.061 12.5 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SRPRB PF09439.5 EWM28834.1 - 0.089 12.0 0.1 0.22 10.7 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EWM28835.1 - 5.2e-20 71.5 0.0 1e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EWM28835.1 - 1.6e-10 40.4 0.0 3.3e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EWM28835.1 - 2.2e-06 27.5 0.0 0.017 14.9 0.0 2.4 2 0 0 2 2 2 2 Dynamin family AIG1 PF04548.11 EWM28835.1 - 0.0011 18.1 0.0 0.0016 17.5 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 EWM28835.1 - 0.0062 17.0 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 EWM28835.1 - 0.012 15.5 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Resolvase PF00239.16 EWM28835.1 - 0.022 14.5 0.0 0.052 13.4 0.0 1.6 1 0 0 1 1 1 0 Resolvase, N terminal domain AAA_28 PF13521.1 EWM28835.1 - 0.04 13.8 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF3006 PF11213.3 EWM28835.1 - 0.043 13.5 0.5 0.25 11.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) DUF258 PF03193.11 EWM28835.1 - 0.061 12.5 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SRPRB PF09439.5 EWM28835.1 - 0.089 12.0 0.1 0.22 10.7 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit CDP-OH_P_transf PF01066.16 EWM28836.1 - 2.4e-16 59.8 1.4 4.6e-16 58.9 0.9 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase DUF2042 PF09743.4 EWM28837.1 - 4.7e-63 213.0 0.0 6.6e-63 212.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2042) Hexapep PF00132.19 EWM28838.1 - 4.2e-16 57.6 3.3 6.2e-05 22.3 0.0 4.3 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EWM28838.1 - 5.6e-07 28.9 0.9 0.00042 19.8 0.0 3.6 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase Fe-S_biosyn PF01521.15 EWM28839.1 - 2.6e-17 62.7 0.0 3.4e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis FAP PF07174.6 EWM28839.1 - 0.36 10.0 9.8 0.58 9.4 6.8 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF605 PF04652.11 EWM28839.1 - 1.9 7.7 10.0 2.5 7.4 6.9 1.1 1 0 0 1 1 1 0 Vta1 like GST_C_2 PF13410.1 EWM28840.1 - 2.1e-14 53.1 0.2 4.9e-14 51.9 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EWM28840.1 - 3.7e-11 42.8 0.0 8.6e-11 41.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EWM28840.1 - 1.9e-08 34.1 0.0 3.2e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EWM28840.1 - 9e-06 26.1 0.0 2e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EWM28840.1 - 0.043 14.0 0.9 2.1 8.6 0.0 2.8 3 0 0 3 3 3 0 Glutathione S-transferase, N-terminal domain hEGF PF12661.2 EWM28840.1 - 4.5 7.5 6.0 0.79 9.9 0.8 2.3 2 0 0 2 2 2 0 Human growth factor-like EGF GST_C_2 PF13410.1 EWM28841.1 - 2.7e-14 52.7 0.2 6.2e-14 51.6 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EWM28841.1 - 4.7e-11 42.5 0.0 1.1e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EWM28841.1 - 2.4e-08 33.8 0.0 4e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EWM28841.1 - 1.4e-05 25.4 0.0 2.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EWM28841.1 - 0.064 13.4 0.9 2.5 8.3 0.0 2.8 3 0 0 3 3 3 0 Glutathione S-transferase, N-terminal domain SR-25 PF10500.4 EWM28842.1 - 0.041 13.3 6.7 0.091 12.2 4.7 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.4 EWM28842.1 - 0.14 10.4 1.7 0.23 9.6 1.2 1.2 1 0 0 1 1 1 0 Transmembrane protein OTCace_N PF02729.16 EWM28844.1 - 4e-43 146.4 0.0 6.6e-43 145.7 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 EWM28844.1 - 8.5e-43 145.9 0.0 2.9e-42 144.2 0.0 1.8 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 EWM28845.1 - 4e-43 146.4 0.0 6.6e-43 145.7 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 EWM28845.1 - 8.5e-43 145.9 0.0 2.9e-42 144.2 0.0 1.8 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 EWM28846.1 - 3.8e-43 146.5 0.0 6.4e-43 145.8 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 EWM28846.1 - 8.1e-43 146.0 0.0 2.8e-42 144.2 0.0 1.8 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Peptidase_C1 PF00112.18 EWM28848.1 - 4.1e-21 75.8 0.2 6.8e-21 75.1 0.1 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EWM28848.1 - 2.6e-08 33.9 0.2 4e-08 33.4 0.1 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) TPR_9 PF13371.1 EWM28849.1 - 0.00027 20.7 1.9 0.0012 18.6 0.9 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EWM28849.1 - 0.0013 18.3 0.0 0.0046 16.5 0.0 1.9 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EWM28849.1 - 0.0042 16.8 0.1 0.046 13.6 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EWM28850.1 - 0.00027 20.7 1.9 0.0012 18.6 0.9 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EWM28850.1 - 0.0013 18.3 0.0 0.0046 16.5 0.0 1.9 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EWM28850.1 - 0.0042 16.8 0.1 0.046 13.6 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Aldo_ket_red PF00248.16 EWM28851.1 - 4.1e-41 140.6 0.0 1.8e-33 115.5 0.0 2.1 2 0 0 2 2 2 2 Aldo/keto reductase family TPR_11 PF13414.1 EWM28851.1 - 0.0011 18.5 3.1 0.0095 15.5 0.2 3.2 3 1 1 4 4 4 2 TPR repeat TPR_9 PF13371.1 EWM28851.1 - 0.002 17.9 1.5 0.002 17.9 1.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EWM28851.1 - 0.45 10.5 6.5 0.25 11.3 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1301 PF06979.7 EWM28852.1 - 1.3e-09 38.3 2.0 0.00077 19.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1301) UBA PF00627.26 EWM28853.1 - 0.02 14.7 0.1 0.048 13.5 0.0 1.7 2 0 0 2 2 2 0 UBA/TS-N domain SecA_SW PF07516.8 EWM28853.1 - 0.12 12.1 0.3 0.2 11.3 0.2 1.4 1 0 0 1 1 1 0 SecA Wing and Scaffold domain UBA PF00627.26 EWM28854.1 - 1.6e-09 37.3 0.7 2.6e-09 36.6 0.5 1.4 1 0 0 1 1 1 1 UBA/TS-N domain DER1 PF04511.10 EWM28854.1 - 6.2e-06 25.8 0.1 8.9e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.17 EWM28854.1 - 0.00014 21.8 2.8 0.00014 21.8 2.0 1.8 2 0 0 2 2 2 1 Rhomboid family CUE PF02845.11 EWM28854.1 - 0.008 15.6 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 CUE domain RuvA_C PF07499.8 EWM28854.1 - 0.033 14.3 0.1 0.059 13.5 0.1 1.4 1 0 0 1 1 1 0 RuvA, C-terminal domain CTP_transf_2 PF01467.21 EWM28855.1 - 0.0003 20.8 0.0 0.0013 18.7 0.0 2.0 2 0 0 2 2 2 1 Cytidylyltransferase Lipase_3 PF01764.20 EWM28856.1 - 2.9e-28 98.2 0.0 4.3e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EWM28856.1 - 0.00048 20.0 0.3 0.00076 19.4 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM28856.1 - 0.057 13.1 0.1 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Pkinase PF00069.20 EWM28857.1 - 7.1e-55 185.9 1.6 2.2e-35 122.0 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EWM28857.1 - 7.8e-26 90.6 0.2 5.7e-18 64.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EWM28857.1 - 0.00029 19.8 0.1 0.00088 18.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EWM28857.1 - 0.0011 18.1 0.0 0.0025 16.9 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.19 EWM28857.1 - 0.034 14.6 0.1 0.11 13.0 0.0 1.8 2 0 0 2 2 2 0 Protein kinase C terminal domain OmpH PF03938.9 EWM28857.1 - 0.16 11.9 5.5 0.23 11.3 3.8 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Complex1_LYR PF05347.10 EWM28859.1 - 0.0033 17.1 0.0 0.006 16.3 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EWM28859.1 - 0.036 14.2 0.1 0.056 13.6 0.1 1.3 1 0 0 1 1 1 0 Complex1_LYR-like Mito_carr PF00153.22 EWM28860.1 - 1.5e-55 184.8 2.1 8.1e-19 67.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HI0933_like PF03486.9 EWM28864.1 - 2.7e-40 138.1 0.4 1.2e-24 86.5 0.9 2.0 1 1 1 2 2 2 2 HI0933-like protein GIDA PF01134.17 EWM28864.1 - 0.11 11.3 0.1 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Ribonuc_red_sm PF00268.16 EWM28865.1 - 5.4e-114 379.9 0.3 6.3e-114 379.7 0.2 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain GDC-P PF02347.11 EWM28868.1 - 1.4e-10 40.5 0.0 1.6e-10 40.3 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage system P-protein HATPase_c PF02518.21 EWM28872.1 - 4e-20 71.6 8.4 1e-19 70.2 5.8 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EWM28872.1 - 2.2e-18 66.3 0.0 3.7e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EWM28872.1 - 7.9e-14 51.4 0.0 1.9e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain MASE1 PF05231.9 EWM28872.1 - 0.0048 15.9 38.7 0.0068 15.4 26.8 1.2 1 0 0 1 1 1 1 MASE1 4HBT PF03061.17 EWM28873.1 - 1.3e-07 31.5 0.2 0.015 15.4 0.0 2.5 2 0 0 2 2 2 2 Thioesterase superfamily DUF4442 PF14539.1 EWM28873.1 - 0.14 12.1 0.0 0.63 10.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4442) EVE PF01878.13 EWM28874.1 - 1.7e-50 170.8 0.0 3.1e-50 169.9 0.0 1.4 2 0 0 2 2 2 1 EVE domain GFRP PF06399.8 EWM28876.1 - 0.031 13.8 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) Glyco_hydro_1 PF00232.13 EWM28877.1 - 1.8e-168 560.4 0.5 2.4e-168 560.0 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Nramp PF01566.13 EWM28880.1 - 4.3e-111 371.1 12.4 4.3e-111 371.1 8.6 2.1 1 1 1 2 2 2 1 Natural resistance-associated macrophage protein HMGL-like PF00682.14 EWM28880.1 - 5.9e-80 268.3 0.6 1.1e-79 267.4 0.4 1.5 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 EWM28880.1 - 1.1e-25 89.9 0.2 2.1e-25 89.0 0.2 1.4 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Abhydrolase_6 PF12697.2 EWM28881.1 - 5e-15 56.0 1.4 7.5e-15 55.4 1.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EWM28881.1 - 2.3e-13 49.8 0.3 4.6e-13 48.8 0.2 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 EWM28881.1 - 1.3e-08 34.7 0.0 1.4e-07 31.3 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ribosomal_L18e PF00828.14 EWM28882.1 - 2.3e-18 66.7 0.0 1.4e-17 64.2 0.0 2.2 2 1 1 3 3 3 1 Ribosomal protein L18e/L15 IBR PF01485.16 EWM28883.1 - 0.00024 20.9 4.6 0.00024 20.9 3.2 1.9 2 0 0 2 2 2 1 IBR domain PA PF02225.17 EWM28884.1 - 4.3e-11 42.3 0.0 1.1e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 PA domain RNB PF00773.14 EWM28885.1 - 7.4e-94 314.6 0.0 9.2e-94 314.3 0.0 1.1 1 0 0 1 1 1 1 RNB domain TAP42 PF04177.7 EWM28886.1 - 1.1e-54 185.7 0.2 1.8e-54 185.0 0.1 1.3 1 1 0 1 1 1 1 TAP42-like family PIN_4 PF13638.1 EWM28887.1 - 0.0015 18.5 0.1 0.0021 18.1 0.1 1.2 1 0 0 1 1 1 1 PIN domain HAD PF12710.2 EWM28889.1 - 1.3e-18 67.8 0.0 2.2e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EWM28889.1 - 3.1e-11 44.1 0.1 2.5e-10 41.1 0.0 1.9 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EWM28889.1 - 0.00017 21.8 0.0 0.00032 20.9 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EWM28889.1 - 0.006 15.7 0.0 0.017 14.2 0.0 1.6 1 1 0 1 1 1 1 Putative Phosphatase Acid_phosphat_B PF03767.9 EWM28889.1 - 0.01 15.2 0.1 0.42 9.9 0.0 2.6 2 1 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) HAD PF12710.2 EWM28890.1 - 1.3e-18 67.8 0.0 2.2e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EWM28890.1 - 3.1e-11 44.1 0.0 2.1e-10 41.3 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EWM28890.1 - 0.00017 21.8 0.0 0.00031 20.9 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 EWM28890.1 - 0.0043 16.4 0.1 0.42 9.9 0.0 2.6 2 1 0 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) Put_Phosphatase PF06888.7 EWM28890.1 - 0.014 14.5 0.0 0.042 13.0 0.0 1.6 1 1 0 1 1 1 0 Putative Phosphatase GRAM PF02893.15 EWM28895.1 - 1.6e-12 46.7 0.0 2.8e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 GRAM domain Tad PF13400.1 EWM28895.1 - 1.8 8.6 5.0 5.6 7.0 2.5 2.3 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like FCH PF00611.18 EWM28896.1 - 3.8e-07 30.1 0.0 3.9e-06 26.9 0.0 2.4 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain KfrA_N PF11740.3 EWM28896.1 - 2.5 8.5 8.8 1.8 9.0 0.2 2.7 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term PepX_C PF08530.5 EWM28898.1 - 4.3e-23 82.3 0.0 6.9e-23 81.6 0.0 1.3 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain PepX_C PF08530.5 EWM28899.1 - 4.5e-23 82.2 0.0 6.7e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain DUF605 PF04652.11 EWM28901.1 - 0.24 10.7 7.5 0.3 10.4 5.2 1.4 1 0 0 1 1 1 0 Vta1 like Peptidase_S15 PF02129.13 EWM28902.1 - 7.2e-40 137.1 0.0 1.6e-39 135.9 0.0 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 EWM28902.1 - 4.1e-05 23.5 0.1 6.5e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM28902.1 - 0.0023 17.6 0.0 0.0046 16.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EWM28902.1 - 0.01 15.0 0.4 0.019 14.2 0.2 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 EWM28902.1 - 0.017 14.9 0.0 0.075 12.8 0.0 2.1 2 0 0 2 2 2 0 Putative lysophospholipase DinB_2 PF12867.2 EWM28902.1 - 0.061 13.6 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 DinB superfamily Peptidase_S15 PF02129.13 EWM28903.1 - 5.9e-35 121.0 0.0 1.1e-34 120.0 0.0 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 EWM28903.1 - 8.6e-05 22.5 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM28903.1 - 0.0022 17.7 0.0 0.0038 16.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EWM28903.1 - 0.0087 15.3 0.3 0.014 14.5 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 EWM28903.1 - 0.018 14.8 0.0 0.063 13.1 0.0 1.9 2 0 0 2 2 2 0 Putative lysophospholipase DinB_2 PF12867.2 EWM28903.1 - 0.052 13.8 0.0 0.087 13.1 0.0 1.3 1 0 0 1 1 1 0 DinB superfamily PLDc_2 PF13091.1 EWM28907.1 - 0.015 15.0 0.0 0.019 14.7 0.0 1.1 1 0 0 1 1 1 0 PLD-like domain PLDc PF00614.17 EWM28907.1 - 0.55 10.1 2.1 2.3 8.1 1.5 1.9 1 1 0 1 1 1 0 Phospholipase D Active site motif PLDc_2 PF13091.1 EWM28909.1 - 8.8e-05 22.2 0.0 0.00017 21.3 0.0 1.4 1 0 0 1 1 1 1 PLD-like domain DnaG_DnaB_bind PF08278.6 EWM28909.1 - 0.11 12.6 0.1 0.29 11.3 0.1 1.8 1 1 0 1 1 1 0 DNA primase DnaG DnaB-binding PIP5K PF01504.13 EWM28910.1 - 1.4e-28 99.6 0.1 2.8e-28 98.7 0.1 1.4 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cecropin PF00272.14 EWM28910.1 - 0.14 11.7 2.0 0.97 9.0 1.4 2.1 1 1 0 1 1 1 0 Cecropin family Lsr2 PF11774.3 EWM28911.1 - 1.1 9.2 5.5 1.1 9.1 3.8 1.1 1 0 0 1 1 1 0 Lsr2 Polysacc_lyase PF14099.1 EWM28912.1 - 3.7e-22 79.1 0.4 5.9e-22 78.4 0.3 1.2 1 0 0 1 1 1 1 Polysaccharide lyase zf-CCCH PF00642.19 EWM28914.1 - 1.1 8.9 8.7 1.2 8.8 0.4 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF3593 PF12159.3 EWM28918.1 - 6.2e-25 86.8 0.5 9.3e-25 86.2 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3593) DUF2269 PF10027.4 EWM28918.1 - 0.062 13.0 0.2 0.66 9.7 0.0 2.1 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) Mito_carr PF00153.22 EWM28919.1 - 2e-09 36.9 0.1 3.4e-09 36.2 0.0 1.4 2 0 0 2 2 2 1 Mitochondrial carrier protein T4-Gluco-transf PF09198.5 EWM28919.1 - 0.044 13.1 0.0 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 Bacteriophage T4 beta-glucosyltransferase EF-hand_8 PF13833.1 EWM28922.1 - 3.6e-20 71.3 1.9 3.1e-06 26.7 0.0 4.3 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.27 EWM28922.1 - 1.7e-18 64.4 2.8 0.00066 18.7 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EWM28922.1 - 9.1e-18 64.1 0.3 2.1e-09 37.4 0.0 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EWM28922.1 - 1.2e-14 52.7 0.3 0.025 14.4 0.0 4.7 4 0 0 4 4 4 4 EF-hand domain 5_nucleotid_C PF02872.13 EWM28922.1 - 2.8e-14 53.3 0.0 6.2e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain EF-hand_5 PF13202.1 EWM28922.1 - 1e-11 43.5 2.8 0.0028 16.9 0.0 4.4 4 0 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.4 EWM28922.1 - 0.0013 18.6 0.1 0.036 14.1 0.0 2.7 2 1 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region bPH_2 PF03703.9 EWM28923.1 - 2.1e-15 56.4 0.4 3e-15 55.9 0.3 1.3 1 0 0 1 1 1 1 Bacterial PH domain DUF1205 PF06722.7 EWM28923.1 - 0.03 14.5 0.0 0.57 10.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1205) PPR PF01535.15 EWM28924.1 - 0.1 12.6 0.0 1.1 9.3 0.0 2.5 2 0 0 2 2 2 0 PPR repeat Fip1 PF05182.8 EWM28927.1 - 3.1e-15 55.1 0.4 5.5e-15 54.3 0.3 1.4 1 0 0 1 1 1 1 Fip1 motif AhpC-TSA PF00578.16 EWM28928.1 - 2.6e-34 117.5 0.0 3.8e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EWM28928.1 - 1.4e-13 50.5 0.0 2e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin DIOX_N PF14226.1 EWM28929.1 - 1e-22 80.8 0.0 1.7e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EWM28929.1 - 1.7e-14 53.8 0.0 2.7e-07 30.7 0.0 2.4 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily Ribonuc_2-5A PF06479.7 EWM28934.1 - 7.3e-33 113.1 0.0 1.1e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 EWM28934.1 - 1.9e-28 99.3 0.0 1.3e-10 40.9 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EWM28934.1 - 1.2e-13 50.7 0.0 9.7e-10 37.9 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 EWM28934.1 - 0.011 14.7 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ_2 PF13360.1 EWM28935.1 - 0.00026 20.5 1.6 0.003 17.0 0.5 2.9 1 1 1 2 2 2 2 PQQ-like domain PQQ_3 PF13570.1 EWM28935.1 - 0.0018 18.4 1.1 2.9 8.3 0.0 4.5 3 1 0 3 3 3 1 PQQ-like domain PQQ PF01011.16 EWM28935.1 - 0.0096 15.4 0.3 7 6.3 0.1 2.7 2 0 0 2 2 2 2 PQQ enzyme repeat DUF600 PF04634.7 EWM28936.1 - 0.0048 16.9 0.0 0.0073 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF600 Cupin_2 PF07883.6 EWM28938.1 - 0.00011 21.5 0.5 0.00047 19.6 0.3 2.0 1 1 0 1 1 1 1 Cupin domain Auxin_BP PF02041.11 EWM28938.1 - 0.011 15.2 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 Auxin binding protein PepSY_TM_2 PF13703.1 EWM28938.1 - 0.03 14.4 0.7 0.047 13.8 0.5 1.3 1 0 0 1 1 1 0 PepSY-associated TM helix DUF4635 PF15466.1 EWM28938.1 - 0.13 11.5 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) Cupin_2 PF07883.6 EWM28939.1 - 0.00011 21.5 0.5 0.00047 19.6 0.3 2.0 1 1 0 1 1 1 1 Cupin domain Auxin_BP PF02041.11 EWM28939.1 - 0.011 15.2 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 Auxin binding protein PepSY_TM_2 PF13703.1 EWM28939.1 - 0.03 14.4 0.7 0.047 13.8 0.5 1.3 1 0 0 1 1 1 0 PepSY-associated TM helix DUF4635 PF15466.1 EWM28939.1 - 0.13 11.5 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) Pkinase PF00069.20 EWM28941.1 - 9.5e-60 201.9 0.0 1.1e-59 201.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM28941.1 - 1.4e-30 106.1 0.0 1.8e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EWM28941.1 - 0.00076 19.2 2.0 0.027 14.1 0.2 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EWM28941.1 - 0.0017 17.4 0.0 0.0027 16.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EWM28941.1 - 0.0027 16.7 0.0 0.0044 16.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EWM28941.1 - 0.033 13.0 0.0 0.055 12.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Mito_carr PF00153.22 EWM28945.1 - 2.4e-52 174.6 8.2 1.8e-21 75.6 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Acatn PF13000.2 EWM28946.1 - 0.007 14.9 0.3 0.0087 14.6 0.2 1.0 1 0 0 1 1 1 1 Acetyl-coenzyme A transporter 1 Acatn PF13000.2 EWM28947.1 - 3.6e-19 68.6 0.0 4e-19 68.5 0.0 1.0 1 0 0 1 1 1 1 Acetyl-coenzyme A transporter 1 IRK PF01007.15 EWM28949.1 - 0.006 15.4 0.4 0.021 13.6 0.3 1.7 1 1 0 1 1 1 1 Inward rectifier potassium channel DUF1601 PF07671.6 EWM28949.1 - 0.038 13.6 0.0 0.073 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1601) DNA_pol_E_B PF04042.11 EWM28950.1 - 8.6e-30 103.5 0.0 1.3e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.5 EWM28950.1 - 7.1e-09 35.5 0.0 1.4e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Reductase_C PF14759.1 EWM28950.1 - 0.12 12.6 0.0 1.6 9.0 0.0 2.5 2 1 0 2 2 2 0 Reductase C-terminal ABC1 PF03109.11 EWM28951.1 - 4.4e-21 75.0 0.0 8.1e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.20 EWM28951.1 - 0.00032 19.9 0.0 0.0013 17.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 EWM28951.1 - 0.00049 19.9 0.1 1.2 8.8 0.0 2.6 1 1 0 2 2 2 2 Phosphotransferase enzyme family WaaY PF06176.6 EWM28951.1 - 0.003 16.8 0.2 0.21 10.7 0.1 2.2 2 0 0 2 2 2 2 Lipopolysaccharide core biosynthesis protein (WaaY) CTDII PF01556.13 EWM28954.1 - 1.6e-11 43.9 0.1 2.5e-11 43.3 0.1 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain SR-25 PF10500.4 EWM28954.1 - 0.066 12.6 11.3 0.071 12.5 7.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CBS PF00571.23 EWM28955.1 - 4.1e-11 42.4 0.8 9e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 CBS domain E2 PF08199.6 EWM28955.1 - 0.3 10.6 0.2 0.3 10.6 0.1 1.7 2 0 0 2 2 2 0 Bacteriophage E2-like protein L27_2 PF09045.5 EWM28955.1 - 0.7 9.4 4.3 0.24 10.9 0.7 1.8 2 0 0 2 2 2 0 L27_2 DnaJ PF00226.26 EWM28956.1 - 2.5e-11 43.1 0.0 3.6e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Ribosomal_L18p PF00861.17 EWM28957.1 - 6.2e-43 145.7 0.2 6.2e-43 145.7 0.1 1.6 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EWM28957.1 - 6.7e-27 93.8 4.0 6.7e-27 93.8 2.8 2.1 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region zf-CCCH_2 PF14608.1 EWM28958.1 - 1.7 8.7 5.5 2 8.5 0.8 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type zf-CCCH PF00642.19 EWM28958.1 - 9.1 6.0 6.9 5.7 6.7 1.6 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CDC45 PF02724.9 EWM28959.1 - 0.044 11.8 8.6 0.055 11.4 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.17 EWM28959.1 - 0.054 12.5 10.3 0.07 12.1 7.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Daxx PF03344.10 EWM28959.1 - 0.15 10.5 12.8 0.2 10.1 8.9 1.1 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 EWM28959.1 - 0.35 10.2 5.5 0.47 9.7 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SDA1 PF05285.7 EWM28959.1 - 0.42 9.8 14.6 0.55 9.4 10.1 1.1 1 0 0 1 1 1 0 SDA1 Astro_capsid PF03115.9 EWM28959.1 - 2.4 6.3 3.7 2.9 6.0 2.5 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor LRR_4 PF12799.2 EWM28961.1 - 1.3e-10 40.6 2.7 1.2e-06 27.9 0.1 2.5 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EWM28961.1 - 5e-09 35.7 1.5 3.7e-07 29.7 0.6 2.8 2 1 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.28 EWM28961.1 - 3.4e-07 29.3 3.8 0.031 14.2 0.1 3.6 3 1 1 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.1 EWM28961.1 - 2.2e-05 24.0 1.8 0.1 12.7 0.0 3.6 4 0 0 4 4 4 2 Leucine Rich repeat LRR_7 PF13504.1 EWM28961.1 - 0.00011 21.8 5.2 0.21 11.9 0.0 3.9 4 1 0 4 4 4 2 Leucine rich repeat LRR_9 PF14580.1 EWM28961.1 - 0.019 14.5 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeat Mucin PF01456.12 EWM28962.1 - 3.2e-07 30.2 4.6 4.5e-07 29.7 3.2 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein PT PF04886.7 EWM28962.1 - 0.014 14.6 24.0 0.014 14.6 16.6 3.5 1 1 2 3 3 3 0 PT repeat TMEMspv1-c74-12 PF11044.3 EWM28962.1 - 0.084 12.4 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein CENP-X PF09415.5 EWM28963.1 - 0.03 14.1 1.2 0.03 14.1 0.8 2.1 2 1 0 2 2 2 0 CENP-S associating Centromere protein X DUF4246 PF14033.1 EWM28963.1 - 0.051 12.1 2.1 0.054 12.1 1.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) Peptidase_M41 PF01434.13 EWM28963.1 - 0.12 11.8 4.6 0.15 11.4 3.2 1.3 1 0 0 1 1 1 0 Peptidase family M41 Fib_alpha PF08702.5 EWM28963.1 - 0.13 12.3 9.1 0.64 10.1 6.2 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Secretogranin_V PF05281.6 EWM28963.1 - 0.77 9.1 4.3 0.9 8.8 3.0 1.1 1 0 0 1 1 1 0 Neuroendocrine protein 7B2 precursor (Secretogranin V) Atg14 PF10186.4 EWM28963.1 - 1.4 7.7 14.7 1.9 7.3 10.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 T2SM PF04612.7 EWM28963.1 - 1.9 8.2 10.5 2.4 7.9 7.3 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Sox_N PF12444.3 EWM28963.1 - 2.4 9.3 6.1 1 10.4 2.5 1.7 1 1 1 2 2 2 0 Sox developmental protein N terminal DUF1451 PF07295.6 EWM28963.1 - 2.4 7.9 10.4 3.3 7.4 7.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1451) Jnk-SapK_ap_N PF09744.4 EWM28963.1 - 3.5 7.6 17.7 4.3 7.2 12.2 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 IncA PF04156.9 EWM28963.1 - 3.6 7.1 21.6 4.7 6.7 15.0 1.2 1 0 0 1 1 1 0 IncA protein FUSC PF04632.7 EWM28963.1 - 3.9 5.7 8.5 4.8 5.5 5.9 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DivIVA PF05103.8 EWM28963.1 - 4.2 7.4 20.2 3 7.9 13.2 1.3 1 1 0 1 1 1 0 DivIVA protein DUF740 PF05340.7 EWM28963.1 - 6.1 5.0 10.2 6.4 5.0 7.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF740) APG6 PF04111.7 EWM28963.1 - 8.6 5.3 17.9 11 5.0 12.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 PMSR PF01625.16 EWM28968.1 - 7.5e-48 162.3 0.0 1.1e-47 161.8 0.0 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase FKBP_C PF00254.23 EWM28968.1 - 1.9e-12 47.0 0.0 1.9e-11 43.7 0.0 2.1 1 1 1 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase PMSR PF01625.16 EWM28969.1 - 7.5e-48 162.3 0.0 1.1e-47 161.8 0.0 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase FKBP_C PF00254.23 EWM28969.1 - 1.9e-12 47.0 0.0 1.9e-11 43.7 0.0 2.1 1 1 1 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Transket_pyr PF02779.19 EWM28970.1 - 6.1e-15 55.1 0.0 8.5e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain CAF1C_H4-bd PF12265.3 EWM28971.1 - 2.4e-18 65.7 0.0 3.9e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Thioredoxin_4 PF13462.1 EWM28972.1 - 2e-11 44.1 0.0 2.8e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EWM28972.1 - 0.0018 18.4 0.0 0.0071 16.5 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain DSBA PF01323.15 EWM28972.1 - 0.032 13.7 0.4 3.5 7.1 0.0 2.6 1 1 1 2 2 2 0 DSBA-like thioredoxin domain BPL_LplA_LipB PF03099.14 EWM28973.1 - 2.4e-17 63.1 0.0 3.7e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DJ-1_PfpI PF01965.19 EWM28974.1 - 8.7e-27 93.3 0.0 1.2e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EWM28974.1 - 4.5e-12 45.5 0.1 6e-12 45.1 0.1 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EWM28975.1 - 1.1e-26 93.0 0.0 1.6e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EWM28975.1 - 6e-12 45.1 0.1 8.1e-12 44.7 0.1 1.2 1 0 0 1 1 1 1 Putative amidotransferase adh_short PF00106.20 EWM28976.1 - 1.9e-24 86.4 0.1 7.4e-24 84.5 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EWM28976.1 - 1.9e-09 37.6 0.0 2.5e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EWM28976.1 - 6.5e-08 32.0 0.0 1.3e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) KR PF08659.5 EWM28976.1 - 6.2e-07 29.2 0.0 1.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EWM28976.1 - 0.0023 17.6 0.3 0.07 12.9 0.1 2.3 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EWM28976.1 - 0.028 14.4 0.7 0.59 10.1 0.1 2.5 2 1 1 3 3 3 0 NADH(P)-binding adh_short PF00106.20 EWM28977.1 - 1.6e-24 86.6 0.1 6.7e-24 84.6 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EWM28977.1 - 1.6e-09 37.9 0.0 2.1e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EWM28977.1 - 3.4e-08 32.9 0.0 7.2e-07 28.6 0.0 2.2 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) KR PF08659.5 EWM28977.1 - 6.2e-07 29.2 0.0 1.2e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EWM28977.1 - 0.0026 17.5 0.3 0.067 12.9 0.1 2.3 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EWM28977.1 - 0.026 14.5 0.8 0.44 10.5 0.1 2.6 2 1 1 3 3 3 0 NADH(P)-binding PPTA PF01239.17 EWM28978.1 - 5.6e-30 101.4 6.3 8.3e-10 37.5 0.1 5.2 5 0 0 5 5 5 4 Protein prenyltransferase alpha subunit repeat RPE65 PF03055.10 EWM28979.1 - 1.4e-25 89.8 0.0 2e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Rb_C PF08934.5 EWM28980.1 - 0.094 12.3 0.1 0.094 12.3 0.1 1.2 1 0 0 1 1 1 0 Rb C-terminal domain DUF1602 PF07673.9 EWM28980.1 - 1.7 8.1 10.7 0.18 11.2 2.9 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1602) AAA_5 PF07728.9 EWM28981.1 - 7.2e-06 25.7 0.3 5.6e-05 22.8 0.0 2.1 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.24 EWM28981.1 - 8e-05 22.8 0.0 0.00015 22.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EWM28981.1 - 0.00034 20.5 0.0 0.00066 19.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 EWM28981.1 - 0.00037 19.7 0.9 0.0031 16.7 0.0 2.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 EWM28981.1 - 0.00049 20.1 0.0 0.00098 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.21 EWM28981.1 - 0.00082 18.8 0.0 0.0015 18.0 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain TIP49 PF06068.8 EWM28981.1 - 0.00085 18.1 0.0 0.0011 17.7 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 EWM28981.1 - 0.0019 18.9 0.0 0.0036 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EWM28981.1 - 0.0043 17.3 0.0 0.0071 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EWM28981.1 - 0.0062 16.5 0.1 0.012 15.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EWM28981.1 - 0.01 14.9 0.0 0.019 14.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin ResIII PF04851.10 EWM28981.1 - 0.011 15.5 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit T2SE PF00437.15 EWM28981.1 - 0.014 14.2 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 EWM28981.1 - 0.015 15.0 0.0 0.042 13.5 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 EWM28981.1 - 0.015 15.4 0.0 0.03 14.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.15 EWM28981.1 - 0.019 13.6 0.1 0.021 13.5 0.1 1.1 1 0 0 1 1 1 0 G-protein alpha subunit CPT PF07931.7 EWM28981.1 - 0.025 14.2 0.0 0.06 12.9 0.0 1.7 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 EWM28981.1 - 0.037 13.9 0.3 0.21 11.4 0.0 2.2 2 1 0 2 2 2 0 AAA domain MCM PF00493.18 EWM28981.1 - 0.037 12.8 0.0 0.064 12.0 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family IstB_IS21 PF01695.12 EWM28981.1 - 0.04 13.3 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DEAD PF00270.24 EWM28981.1 - 0.1 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase DUF3112 PF11309.3 EWM28982.1 - 0.064 13.0 5.1 0.084 12.6 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) MARVEL PF01284.18 EWM28982.1 - 0.26 11.1 16.8 12 5.6 11.7 2.2 1 1 0 1 1 1 0 Membrane-associating domain ELO PF01151.13 EWM28982.1 - 2.8 7.1 10.8 3.7 6.7 7.5 1.1 1 0 0 1 1 1 0 GNS1/SUR4 family DUF3397 PF11877.3 EWM28982.1 - 3.9 7.5 10.0 5.3 7.0 4.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3397) DUF2678 PF10856.3 EWM28982.1 - 4.5 7.0 7.6 18 5.0 4.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2678) AAA_2 PF07724.9 EWM28983.1 - 5.1e-18 65.5 0.0 1.3e-17 64.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EWM28983.1 - 3e-05 23.8 0.2 5.2e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EWM28983.1 - 8.1e-05 22.8 0.0 0.00021 21.4 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Acyltransferase PF01553.16 EWM28984.1 - 1.9e-06 27.3 0.0 3.4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DUF898 PF05987.8 EWM28984.1 - 0.05 12.4 3.7 0.078 11.8 2.6 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Pox_Rap94 PF03294.9 EWM28984.1 - 0.29 9.0 0.0 0.41 8.5 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase-associated transcription specificity factor, Rap94 Pyridox_oxidase PF01243.15 EWM28985.1 - 6.2e-11 42.1 0.0 1.2e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 EWM28985.1 - 0.0014 18.5 0.0 0.0073 16.1 0.0 1.9 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase GRP PF07172.6 EWM28985.1 - 0.34 11.4 25.1 1 9.8 17.4 1.9 1 1 0 1 1 1 0 Glycine rich protein family YqeY PF09424.5 EWM28987.1 - 4.8e-41 139.9 7.6 5.6e-41 139.7 5.3 1.0 1 0 0 1 1 1 1 Yqey-like protein GatB_Yqey PF02637.13 EWM28987.1 - 0.0013 18.5 4.3 0.0037 16.9 3.0 1.9 1 1 0 1 1 1 1 GatB domain DUF445 PF04286.7 EWM28987.1 - 0.043 13.3 2.4 0.066 12.7 1.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) CENP-X PF09415.5 EWM28987.1 - 0.078 12.8 0.3 0.27 11.0 0.1 1.9 2 0 0 2 2 2 0 CENP-S associating Centromere protein X Polyketide_cyc PF03364.15 EWM28988.1 - 6.3e-07 29.4 0.2 1.2e-06 28.5 0.2 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 EWM28988.1 - 4.9e-06 26.7 0.1 1.1e-05 25.6 0.0 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport ParcG PF10274.4 EWM28989.1 - 1.6e-42 145.5 0.0 1.9e-42 145.2 0.0 1.0 1 0 0 1 1 1 1 Parkin co-regulated protein SET PF00856.23 EWM28991.1 - 3.2e-09 37.3 1.6 6.1e-05 23.3 0.3 2.2 1 1 1 2 2 2 2 SET domain SET PF00856.23 EWM28994.1 - 0.0012 19.2 0.0 0.0022 18.2 0.0 1.5 1 0 0 1 1 1 1 SET domain Pkinase PF00069.20 EWM28995.1 - 3.1e-31 108.4 0.0 3.8e-31 108.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM28995.1 - 3.5e-19 68.8 0.0 4.4e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RskA PF10099.4 EWM28996.1 - 0.33 10.6 1.4 5 6.8 0.1 2.2 1 1 1 2 2 2 0 Anti-sigma-K factor rskA RskA PF10099.4 EWM28997.1 - 0.33 10.6 1.4 5 6.8 0.1 2.2 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Pterin_4a PF01329.14 EWM29000.1 - 3.6e-30 103.5 0.8 4.5e-30 103.2 0.6 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase IF-2 PF11987.3 EWM29000.1 - 0.038 13.8 0.1 0.064 13.1 0.1 1.3 1 0 0 1 1 1 0 Translation-initiation factor 2 SBBP PF06739.6 EWM29001.1 - 0.0029 17.3 3.0 0.0055 16.4 2.1 1.5 1 0 0 1 1 1 1 Beta-propeller repeat Pkinase PF00069.20 EWM29002.1 - 0.00026 20.2 0.0 0.00031 19.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain FlxA PF14282.1 EWM29003.1 - 0.29 11.0 6.0 0.12 12.3 0.4 2.6 2 0 0 2 2 2 0 FlxA-like protein DUF3829 PF12889.2 EWM29003.1 - 5.6 6.0 9.4 1.4 8.0 3.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) SPT16 PF08644.6 EWM29003.1 - 8.1 6.2 7.1 18 5.1 0.9 2.2 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) Cupin_8 PF13621.1 EWM29005.1 - 4.9e-60 203.1 0.0 6.1e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EWM29005.1 - 3.4e-05 23.2 0.5 0.0046 16.2 0.2 2.9 3 0 0 3 3 3 2 Cupin superfamily protein JmjC PF02373.17 EWM29005.1 - 0.025 14.8 0.0 0.052 13.7 0.0 1.5 1 0 0 1 1 1 0 JmjC domain, hydroxylase Trm112p PF03966.11 EWM29006.1 - 1.6e-06 28.3 0.0 1.9e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Trm112p-like protein Proteasome PF00227.21 EWM29007.1 - 1.5e-39 135.2 0.1 2.3e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EWM29007.1 - 3.5e-15 55.0 0.3 1.2e-14 53.3 0.1 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF2890 PF11081.3 EWM29009.1 - 0.12 12.3 1.2 2.5 8.1 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) CENP-B_dimeris PF09026.5 EWM29009.1 - 0.14 12.3 3.7 0.26 11.5 2.3 1.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain SE PF08491.5 EWM29010.1 - 5.6e-87 291.0 0.0 7.7e-87 290.6 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 EWM29010.1 - 8.3e-14 51.3 0.2 4e-06 26.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EWM29010.1 - 4.3e-09 35.7 0.7 3.6e-06 26.1 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EWM29010.1 - 2.2e-05 24.3 0.4 5.9e-05 23.0 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EWM29010.1 - 2.4e-05 23.3 0.2 8.8e-05 21.5 0.1 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EWM29010.1 - 4.8e-05 22.3 0.8 0.0001 21.2 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EWM29010.1 - 6.5e-05 22.8 0.1 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EWM29010.1 - 0.00011 21.3 0.0 0.00025 20.2 0.0 1.4 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EWM29010.1 - 0.00028 19.4 0.5 0.00039 18.9 0.4 1.1 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 EWM29010.1 - 0.00092 18.4 0.1 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EWM29010.1 - 0.0013 17.7 1.3 0.81 8.5 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Shikimate_DH PF01488.15 EWM29010.1 - 0.004 17.2 0.0 0.0077 16.3 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EWM29010.1 - 0.0057 16.3 0.1 0.01 15.4 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 EWM29010.1 - 0.054 12.1 0.2 0.15 10.6 0.2 1.7 2 0 0 2 2 2 0 Tryptophan halogenase NAD_Gly3P_dh_N PF01210.18 EWM29010.1 - 0.084 12.5 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_3 PF13738.1 EWM29010.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 EWM29010.1 - 0.18 11.1 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Nup84_Nup100 PF04121.8 EWM29011.1 - 1.1e-13 49.7 0.0 1.2e-13 49.7 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 DEAD PF00270.24 EWM29012.1 - 3.2e-25 88.5 0.0 5.9e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EWM29012.1 - 9.8e-19 67.0 0.1 2e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TGF_beta_GS PF08515.7 EWM29013.1 - 0.11 11.8 0.1 0.2 10.9 0.1 1.4 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif DDT PF02791.12 EWM29014.1 - 0.011 15.5 0.2 0.071 12.8 0.0 2.1 2 0 0 2 2 2 0 DDT domain WHIM2 PF15613.1 EWM29014.1 - 0.021 14.7 1.3 0.051 13.5 0.9 1.6 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 2 DUF2130 PF09903.4 EWM29015.1 - 0.036 12.7 0.0 0.057 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) DUF947 PF06102.7 EWM29016.1 - 2.8e-42 144.3 17.1 2.8e-42 144.3 11.9 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF947) Ribosomal_L13 PF00572.13 EWM29017.1 - 2.9e-47 159.9 0.2 3.9e-47 159.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 PWWP PF00855.12 EWM29018.1 - 0.0096 16.1 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 1 PWWP domain Y_phosphatase3 PF13350.1 EWM29020.1 - 1.4e-24 87.2 0.0 3.2e-22 79.5 0.0 2.3 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EWM29020.1 - 3e-10 40.0 0.0 1.4e-09 37.9 0.0 2.2 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 EWM29020.1 - 8e-07 28.5 0.0 4.6e-06 26.0 0.0 2.0 2 0 0 2 2 2 1 Tyrosine phosphatase family CDK2AP PF09806.4 EWM29020.1 - 1.8 8.7 7.1 3.1 7.9 4.9 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Hamartin PF04388.7 EWM29020.1 - 2.8 6.5 4.6 3.4 6.2 3.2 1.1 1 0 0 1 1 1 0 Hamartin protein CAF-1_p150 PF11600.3 EWM29020.1 - 3.5 6.9 5.8 6 6.1 4.0 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal ATP-synt_Eps PF04627.8 EWM29021.1 - 1.2e-13 50.3 0.4 1.6e-13 49.9 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain DUF3721 PF12518.3 EWM29022.1 - 0.056 13.0 1.9 6.3 6.4 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function RRS1 PF04939.7 EWM29024.1 - 9.1e-52 174.8 1.1 1.3e-51 174.2 0.8 1.3 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) PRKCSH PF07915.8 EWM29025.1 - 6.3e-20 71.7 2.1 8.4e-12 45.7 0.3 2.4 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 EWM29025.1 - 8.9e-11 41.4 5.0 0.00022 20.7 0.2 3.8 1 1 2 3 3 3 3 Glucosidase II beta subunit-like protein CCDC155 PF14662.1 EWM29026.1 - 0.064 12.8 0.0 0.081 12.5 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 CD99L2 PF12301.3 EWM29026.1 - 0.085 12.5 1.4 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 CD99 antigen like protein 2 TPK_catalytic PF04263.11 EWM29027.1 - 2.1e-25 88.6 0.0 2.1e-17 62.8 0.0 2.2 2 0 0 2 2 2 2 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 EWM29027.1 - 1.6e-14 53.3 0.0 3.1e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Arm PF00514.18 EWM29029.1 - 2.3e-05 24.0 3.7 0.053 13.3 0.1 4.3 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.4 EWM29029.1 - 0.0076 15.9 0.1 0.73 9.6 0.0 3.1 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain RNA_pol_Rpb2_6 PF00562.23 EWM29030.1 - 1.1e-122 409.5 0.1 1.6e-122 409.0 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EWM29030.1 - 3.7e-55 186.0 0.0 5.5e-55 185.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EWM29030.1 - 3.1e-42 144.1 0.2 6.5e-42 143.0 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EWM29030.1 - 9.8e-30 102.6 0.0 2.3e-29 101.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.11 EWM29030.1 - 1.7e-23 82.1 0.0 3.9e-23 80.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 EWM29030.1 - 3e-20 71.7 0.1 7.8e-20 70.4 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 EWM29030.1 - 3.7e-19 68.4 0.5 7.9e-19 67.3 0.4 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Beta-lactamase PF00144.19 EWM29032.1 - 2e-35 122.4 0.0 3e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.1 EWM29032.1 - 0.093 12.1 0.0 8 5.8 0.0 2.4 2 0 0 2 2 2 0 Beta-lactamase enzyme family SET PF00856.23 EWM29033.1 - 7.8e-23 81.5 0.0 7.2e-22 78.4 0.0 1.9 1 1 0 1 1 1 1 SET domain E2F_TDP PF02319.15 EWM29035.1 - 4.9e-29 99.6 2.7 1.3e-17 63.1 0.0 2.2 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain ArfGap PF01412.13 EWM29036.1 - 3.8e-15 55.6 0.2 4.3e-15 55.5 0.1 1.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Opiods_neuropep PF01160.13 EWM29036.1 - 0.014 15.0 1.2 0.021 14.5 0.8 1.2 1 0 0 1 1 1 0 Vertebrate endogenous opioids neuropeptide DUF2797 PF10977.3 EWM29036.1 - 0.05 13.2 0.1 0.054 13.1 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) ZF-HD_dimer PF04770.7 EWM29036.1 - 0.31 11.1 1.6 0.45 10.5 1.1 1.3 1 1 0 1 1 1 0 ZF-HD protein dimerisation region TF_Zn_Ribbon PF08271.7 EWM29036.1 - 0.75 9.1 4.1 5.9 6.2 1.7 2.3 2 1 0 2 2 2 0 TFIIB zinc-binding HSA PF07529.8 EWM29037.1 - 7.2e-16 57.7 0.7 7.2e-16 57.7 0.5 3.5 4 0 0 4 4 4 1 HSA SNF2_N PF00176.18 EWM29037.1 - 4.1e-09 35.6 0.0 9.4e-09 34.4 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Myb_DNA-bind_6 PF13921.1 EWM29037.1 - 0.04 14.0 0.0 0.12 12.4 0.0 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain Sigma70_ner PF04546.8 EWM29037.1 - 6.9 6.2 22.9 6.6 6.2 6.8 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region Laminin_II PF06009.7 EWM29038.1 - 0.0013 18.5 2.2 0.0013 18.5 1.5 4.7 3 3 1 4 4 4 2 Laminin Domain II Erp_C PF06780.6 EWM29038.1 - 0.21 11.3 12.2 1.5 8.6 4.8 3.0 1 1 1 2 2 2 0 Erp protein C-terminus AAA_13 PF13166.1 EWM29038.1 - 0.34 9.3 33.9 0.17 10.3 11.9 3.4 2 1 2 4 4 4 0 AAA domain NGP1NT PF08153.7 EWM29039.1 - 6.4e-39 132.8 0.0 1.4e-38 131.7 0.0 1.6 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EWM29039.1 - 3.7e-18 65.5 0.2 1.3e-15 57.3 0.0 3.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EWM29039.1 - 2.1e-06 27.0 0.2 0.00011 21.5 0.1 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.16 EWM29039.1 - 1.4e-05 24.4 0.1 0.078 12.2 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family DUF258 PF03193.11 EWM29039.1 - 0.00011 21.3 0.0 0.00071 18.8 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function, DUF258 Daxx PF03344.10 EWM29039.1 - 0.097 11.1 48.5 0.16 10.4 33.6 1.3 1 0 0 1 1 1 0 Daxx Family CENP-T PF15511.1 EWM29039.1 - 0.2 10.8 29.8 0.44 9.7 20.7 1.5 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T SprA-related PF12118.3 EWM29039.1 - 0.4 9.9 24.3 0.74 9.0 16.9 1.3 1 0 0 1 1 1 0 SprA-related family Zip PF02535.17 EWM29039.1 - 2.1 7.2 8.1 3.7 6.4 5.6 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Merozoite_SPAM PF07133.6 EWM29039.1 - 2.4 8.0 56.8 6.7 6.5 39.4 1.7 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Nop14 PF04147.7 EWM29039.1 - 3.2 5.5 50.5 4.7 4.9 35.0 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EWM29039.1 - 5.5 4.8 31.2 8.9 4.2 21.6 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 EWM29039.1 - 7.6 5.8 40.1 13 5.0 27.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Spore_coat_CotO PF14153.1 EWM29039.1 - 8.3 5.8 35.6 15 4.9 24.7 1.4 1 0 0 1 1 1 0 Spore coat protein CotO DAGAT PF03982.8 EWM29040.1 - 2.9e-22 78.7 0.0 2.8e-20 72.2 0.0 2.1 2 0 0 2 2 2 2 Diacylglycerol acyltransferase UDPGP PF01704.13 EWM29041.1 - 4.1e-07 28.8 0.0 5.7e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase B12D PF06522.6 EWM29042.1 - 9.2e-05 22.0 0.0 0.00018 21.1 0.0 1.4 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit GTP_cyclohydro2 PF00925.15 EWM29043.1 - 5.3e-59 198.2 0.0 8.6e-59 197.5 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II DHBP_synthase PF00926.14 EWM29043.1 - 1.3e-06 27.8 0.0 0.31 10.2 0.0 3.8 3 1 0 3 3 3 3 3,4-dihydroxy-2-butanone 4-phosphate synthase Adaptin_N PF01602.15 EWM29045.1 - 0.054 11.8 0.4 3.3 5.9 0.0 3.3 2 1 0 3 3 3 0 Adaptin N terminal region PhyH PF05721.8 EWM29048.1 - 4.5e-54 183.6 0.1 5.3e-54 183.4 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) HhH-GPD PF00730.20 EWM29049.1 - 1.1e-14 54.5 0.0 2.6e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Epimerase PF01370.16 EWM29050.1 - 6.5e-12 45.3 0.1 6.6e-11 42.0 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EWM29050.1 - 4e-05 23.6 0.0 6.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EWM29050.1 - 0.00051 19.0 0.0 0.044 12.6 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein RNA_pol_Rpb5_C PF01191.14 EWM29051.1 - 9.6e-34 114.8 1.5 1.2e-33 114.5 0.2 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EWM29051.1 - 2.4e-17 63.0 0.1 4.5e-17 62.2 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain AAA_3 PF07726.6 EWM29051.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Coagulase PF08764.5 EWM29051.1 - 0.17 11.8 0.1 0.21 11.4 0.0 1.1 1 0 0 1 1 1 0 Staphylococcus aureus coagulase Asp PF00026.18 EWM29052.1 - 2.3e-22 79.6 0.0 2e-09 37.1 0.0 3.3 3 1 0 3 3 3 3 Eukaryotic aspartyl protease TAXi_C PF14541.1 EWM29052.1 - 3.8e-07 29.8 0.0 0.03 13.8 0.0 3.2 3 0 0 3 3 3 3 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EWM29052.1 - 0.0003 21.2 0.2 8.9 6.8 0.0 3.5 3 0 0 3 3 3 2 Aspartyl protease TAXi_N PF14543.1 EWM29052.1 - 0.0025 17.7 2.8 0.022 14.6 1.4 2.4 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 EWM29052.1 - 0.09 12.6 0.4 13 5.6 0.1 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease AATase PF07247.7 EWM29053.1 - 3.4e-14 52.2 0.0 9.8e-13 47.4 0.0 2.5 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 EWM29053.1 - 3.7e-09 35.8 0.4 2.1e-07 30.1 0.0 2.1 2 0 0 2 2 2 2 Condensation domain RRM_1 PF00076.17 EWM29054.1 - 4.6e-71 234.4 0.4 5.1e-15 54.8 0.1 6.3 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM29054.1 - 2.8e-64 213.0 0.6 3.1e-14 52.7 0.0 6.0 5 1 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM29054.1 - 2.6e-34 116.8 0.0 2.4e-09 36.9 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transgly PF00912.17 EWM29054.1 - 9.9e-05 21.7 0.0 0.0002 20.7 0.0 1.4 1 0 0 1 1 1 1 Transglycosylase Mito_carr PF00153.22 EWM29056.1 - 1.6e-71 236.0 0.0 3.8e-23 81.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PALP PF00291.20 EWM29059.1 - 2e-59 201.3 1.0 2.5e-59 201.0 0.7 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NAD_binding_7 PF13241.1 EWM29059.1 - 0.038 14.2 0.0 0.086 13.1 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Abhydrolase_6 PF12697.2 EWM29060.1 - 5.7e-11 42.7 0.0 8.2e-11 42.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM29060.1 - 4.5e-06 26.4 0.0 5.9e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EWM29060.1 - 7.8e-05 22.3 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.15 EWM29060.1 - 0.00017 21.2 0.0 0.00019 21.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.9 EWM29060.1 - 0.0016 17.7 0.0 0.0026 17.0 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF900 PF05990.7 EWM29060.1 - 0.0049 16.2 0.0 0.0078 15.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) DLH PF01738.13 EWM29060.1 - 0.013 14.7 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF2305 PF10230.4 EWM29060.1 - 0.015 14.7 0.0 0.024 14.0 0.0 1.4 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) LCAT PF02450.10 EWM29060.1 - 0.017 14.1 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.20 EWM29060.1 - 0.042 13.4 0.0 0.11 12.1 0.0 1.6 2 0 0 2 2 2 0 Lipase (class 3) Cyclin_N PF00134.18 EWM29061.1 - 1.2e-13 50.7 0.0 2.3e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.14 EWM29061.1 - 0.063 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Transcription factor TFIIB repeat DUF1777 PF08648.7 EWM29061.1 - 9.9 5.8 25.3 18 5.0 17.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Ras PF00071.17 EWM29062.1 - 6.3e-59 197.9 0.1 8.2e-59 197.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EWM29062.1 - 9.9e-20 71.2 0.1 1.5e-19 70.6 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EWM29062.1 - 8.8e-13 47.8 0.1 1.3e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EWM29062.1 - 1e-06 28.7 0.0 1.6e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EWM29062.1 - 0.00012 21.6 0.0 0.00031 20.2 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EWM29062.1 - 0.00094 19.3 0.0 0.0027 17.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 EWM29062.1 - 0.0025 16.9 0.0 0.0038 16.3 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 EWM29062.1 - 0.004 16.3 0.0 0.0097 15.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 KAP_NTPase PF07693.9 EWM29062.1 - 0.024 13.6 0.0 0.053 12.5 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain AAA_24 PF13479.1 EWM29062.1 - 0.033 13.7 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EWM29062.1 - 0.036 13.9 0.0 0.082 12.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EWM29062.1 - 0.044 13.5 0.0 0.47 10.1 0.0 2.3 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 EWM29062.1 - 0.046 14.0 0.0 0.078 13.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 EWM29062.1 - 0.051 13.5 0.3 0.11 12.4 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.5 EWM29062.1 - 0.073 12.2 0.0 0.12 11.5 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Pro_CA PF00484.14 EWM29063.1 - 1.3e-32 112.9 0.6 2.6e-32 111.9 0.0 1.7 2 0 0 2 2 2 1 Carbonic anhydrase DUF2461 PF09365.5 EWM29063.1 - 0.14 11.5 0.1 0.24 10.7 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein (DUF2461) PPR_2 PF13041.1 EWM29064.1 - 5.3e-120 391.3 0.7 2.6e-13 49.7 0.0 18.0 8 4 12 20 20 19 17 PPR repeat family PPR PF01535.15 EWM29064.1 - 1.5e-112 360.0 15.8 2.8e-07 30.0 0.0 21.2 21 0 0 21 21 21 16 PPR repeat PPR_3 PF13812.1 EWM29064.1 - 2.9e-108 345.2 31.2 6.8e-08 32.1 0.0 20.2 20 1 1 21 21 19 16 Pentatricopeptide repeat domain PPR_1 PF12854.2 EWM29064.1 - 1e-80 264.8 0.0 2e-06 27.1 0.0 18.6 18 1 0 18 18 18 14 PPR repeat Apc3 PF12895.2 EWM29064.1 - 2e-17 63.0 0.6 0.17 12.0 0.0 8.6 7 2 1 9 9 9 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EWM29064.1 - 3.1e-11 42.8 35.0 4.6 8.1 0.0 16.5 13 5 6 19 19 17 1 Tetratricopeptide repeat Clathrin PF00637.15 EWM29064.1 - 4e-11 42.6 0.0 0.22 11.0 0.0 7.7 7 3 3 10 10 8 3 Region in Clathrin and VPS TPR_19 PF14559.1 EWM29064.1 - 7.5e-11 42.2 14.8 1.1 9.6 0.5 9.2 7 2 5 12 12 12 1 Tetratricopeptide repeat ECSIT PF06239.6 EWM29064.1 - 3.4e-10 39.1 0.1 3.6 6.3 0.0 8.5 4 4 5 10 10 10 1 Evolutionarily conserved signalling intermediate in Toll pathway TPR_12 PF13424.1 EWM29064.1 - 5.5e-10 39.0 17.7 0.67 9.9 0.5 11.9 8 4 5 14 14 14 2 Tetratricopeptide repeat TPR_7 PF13176.1 EWM29064.1 - 6e-10 38.1 14.6 11 6.0 0.0 12.9 15 0 0 15 15 13 0 Tetratricopeptide repeat MRP-S27 PF10037.4 EWM29064.1 - 4.6e-09 35.7 0.0 0.024 13.5 0.0 5.7 5 2 1 6 6 6 2 Mitochondrial 28S ribosomal protein S27 Ank_2 PF12796.2 EWM29064.1 - 1.4e-06 28.4 3.4 0.088 13.1 0.1 5.4 4 2 1 5 5 5 2 Ankyrin repeats (3 copies) TPR_16 PF13432.1 EWM29064.1 - 1.1e-05 25.9 15.3 40 5.0 0.1 9.9 9 3 2 11 11 9 0 Tetratricopeptide repeat TPR_10 PF13374.1 EWM29064.1 - 3e-05 23.7 22.1 0.73 9.8 0.1 10.7 12 0 0 12 12 12 1 Tetratricopeptide repeat Ank_5 PF13857.1 EWM29064.1 - 0.0001 22.4 4.8 2.2 8.6 0.0 7.6 7 2 3 10 10 8 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EWM29064.1 - 0.00028 21.3 0.4 4.2 8.0 0.0 5.5 3 2 4 7 7 7 1 Ankyrin repeats (many copies) Glyco_trans_4_3 PF12000.3 EWM29064.1 - 0.00077 19.1 0.2 6.1 6.4 0.0 4.4 4 1 0 4 4 4 1 Gkycosyl transferase family 4 group Rep_fac_C PF08542.6 EWM29064.1 - 0.0014 18.5 0.0 14 5.7 0.0 6.6 6 3 0 6 6 6 0 Replication factor C C-terminal domain TPR_15 PF13429.1 EWM29064.1 - 0.005 15.9 1.4 19 4.1 0.0 5.2 4 1 0 5 5 5 0 Tetratricopeptide repeat RICTOR_V PF14668.1 EWM29064.1 - 0.015 15.1 11.6 4.6 7.2 0.1 6.8 7 2 2 9 9 8 0 Rapamycin-insensitive companion of mTOR, domain 5 DUF3368 PF11848.3 EWM29064.1 - 0.094 12.2 0.3 78 2.9 0.0 4.6 4 0 0 4 4 4 0 Domain of unknown function (DUF3368) TPR_4 PF07721.9 EWM29064.1 - 0.91 10.1 36.5 0.38 11.3 0.1 11.2 12 0 0 12 12 12 0 Tetratricopeptide repeat TPR_2 PF07719.12 EWM29064.1 - 4.2 7.5 22.6 45 4.3 0.0 9.5 12 0 0 12 12 9 0 Tetratricopeptide repeat Synaptobrevin PF00957.16 EWM29065.1 - 6.3e-18 64.1 0.5 1e-17 63.4 0.3 1.3 1 0 0 1 1 1 1 Synaptobrevin Sec20 PF03908.8 EWM29065.1 - 0.12 12.0 0.2 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Sec20 Snf7 PF03357.16 EWM29066.1 - 9.9e-12 44.5 5.0 1.4e-11 44.0 3.5 1.2 1 0 0 1 1 1 1 Snf7 Rad50_zn_hook PF04423.9 EWM29066.1 - 0.084 12.3 0.9 0.2 11.1 0.0 2.1 2 0 0 2 2 2 0 Rad50 zinc hook motif FAD_binding_2 PF00890.19 EWM29067.1 - 5.6e-125 417.4 4.3 7.5e-125 417.0 3.0 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EWM29067.1 - 4.8e-44 149.3 2.7 7e-44 148.7 1.8 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EWM29067.1 - 4e-08 33.3 0.2 7e-05 22.7 0.1 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EWM29067.1 - 2.3e-06 26.7 1.3 6.2e-05 22.0 0.1 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EWM29067.1 - 1.8e-05 23.9 0.4 0.003 16.7 0.1 2.5 3 0 0 3 3 3 2 Thi4 family GIDA PF01134.17 EWM29067.1 - 0.00017 20.5 4.6 0.0012 17.7 2.3 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EWM29067.1 - 0.012 14.7 0.5 0.012 14.7 0.3 2.2 3 0 0 3 3 3 0 FAD binding domain HI0933_like PF03486.9 EWM29067.1 - 0.016 13.7 2.6 0.03 12.8 1.2 1.9 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.2 EWM29067.1 - 0.043 12.8 7.2 0.17 10.9 5.0 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EWM29068.1 - 1.4e-114 383.1 0.8 1.9e-114 382.7 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EWM29068.1 - 4e-44 149.5 2.7 5.8e-44 149.0 1.8 1.2 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term FAD_binding_2 PF00890.19 EWM29069.1 - 7.7e-115 384.0 0.8 9e-115 383.8 0.6 1.0 1 0 0 1 1 1 1 FAD binding domain Med26 PF08711.6 EWM29070.1 - 1.8e-09 36.9 0.3 4e-09 35.8 0.2 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain TATR PF03430.8 EWM29070.1 - 3 6.3 10.0 5.1 5.6 7.0 1.3 1 0 0 1 1 1 0 Trans-activating transcriptional regulator PNGaseA PF12222.3 EWM29071.1 - 1.6e-45 155.8 1.8 2.9e-26 92.3 2.0 3.1 2 1 0 2 2 2 2 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A AAA_21 PF13304.1 EWM29072.1 - 0.34 10.8 5.9 0.39 10.6 4.1 1.1 1 0 0 1 1 1 0 AAA domain SR-25 PF10500.4 EWM29072.1 - 6.3 6.2 81.3 4.7e+03 -3.2 25.0 2.5 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein GST_N_3 PF13417.1 EWM29073.1 - 2.9e-15 56.2 0.0 6.3e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EWM29073.1 - 6.4e-08 32.4 0.0 1.1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EWM29073.1 - 1.5e-05 25.0 0.0 2.9e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EWM29073.1 - 0.00062 19.6 0.0 0.0013 18.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EWM29073.1 - 0.0039 17.1 0.0 0.015 15.2 0.0 1.9 2 0 0 2 2 2 1 Glutaredoxin GST_C PF00043.20 EWM29073.1 - 0.0067 16.3 0.0 0.017 15.0 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EWM29073.1 - 0.017 15.5 0.0 0.03 14.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Pkinase PF00069.20 EWM29074.1 - 1.1e-72 244.3 0.0 1.5e-72 243.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM29074.1 - 7.1e-33 113.7 0.0 1.1e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 EWM29074.1 - 7.3e-10 38.9 0.0 1.5e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 EWM29074.1 - 1.3e-07 31.6 0.2 3e-07 30.4 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 EWM29074.1 - 1.3e-06 28.6 1.1 9.4e-06 25.8 0.8 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain Kdo PF06293.9 EWM29074.1 - 0.024 13.7 0.2 0.049 12.6 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EWM29074.1 - 0.028 13.3 0.0 0.18 10.7 0.0 2.0 1 1 1 3 3 3 0 Kinase-like Pox_ser-thr_kin PF05445.6 EWM29074.1 - 0.048 12.4 0.5 0.076 11.7 0.3 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YukC PF10140.4 EWM29074.1 - 0.055 12.0 0.0 0.081 11.4 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC RIO1 PF01163.17 EWM29074.1 - 0.13 11.5 0.2 0.23 10.7 0.2 1.3 1 0 0 1 1 1 0 RIO1 family DUF457 PF04307.9 EWM29075.1 - 5.7e-05 22.5 3.5 0.00014 21.2 2.4 1.7 1 1 0 1 1 1 1 Predicted membrane-bound metal-dependent hydrolase (DUF457) PepX_C PF08530.5 EWM29076.1 - 7.7e-26 91.3 0.0 1.9e-25 90.0 0.0 1.6 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.13 EWM29076.1 - 3.4e-24 85.6 0.5 2.2e-23 83.0 0.0 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.2 EWM29076.1 - 0.00096 18.9 0.0 0.0024 17.6 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EWM29076.1 - 0.11 12.4 0.5 0.26 11.1 0.3 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Myotub-related PF06602.9 EWM29077.1 - 5e-107 357.7 0.0 6.6e-107 357.3 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 EWM29077.1 - 0.0012 19.1 0.1 0.003 17.8 0.1 1.7 1 1 0 1 1 1 1 Tyrosine phosphatase family DUF846 PF05832.7 EWM29078.1 - 3.3e-52 175.9 12.0 4.2e-52 175.6 8.3 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) ABC2_membrane_3 PF12698.2 EWM29078.1 - 7.4 5.5 12.7 3.2 6.6 1.7 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein Thr_synth_N PF14821.1 EWM29080.1 - 2e-21 75.8 0.0 4.3e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 EWM29080.1 - 8.3e-17 61.3 0.0 1.1e-07 31.4 0.0 2.2 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme RLL PF10036.4 EWM29081.1 - 4.6e-38 131.0 0.0 6.1e-38 130.6 0.0 1.0 1 0 0 1 1 1 1 Putative carnitine deficiency-associated protein EH_Signature PF15611.1 EWM29081.1 - 0.089 11.8 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 EH_Signature domain RNase_P_Rpp14 PF01900.14 EWM29082.1 - 3.9e-24 84.6 0.0 5.3e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family RNase_P_Rpp14 PF01900.14 EWM29083.1 - 3.9e-24 84.6 0.0 5.3e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family Pkinase PF00069.20 EWM29084.1 - 6.1e-21 74.7 0.0 1.1e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM29084.1 - 2.5e-19 69.3 0.0 6.2e-19 68.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase HATPase_c_3 PF13589.1 EWM29084.1 - 1.2e-18 67.0 0.0 8e-18 64.4 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-CW PF07496.10 EWM29084.1 - 5.4e-09 35.6 2.2 1.2e-08 34.4 1.5 1.6 1 0 0 1 1 1 1 CW-type Zinc Finger HATPase_c PF02518.21 EWM29084.1 - 2.3e-07 30.5 0.1 5.2e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Prefoldin_2 PF01920.15 EWM29085.1 - 3.3e-16 58.9 0.9 4.4e-16 58.5 0.7 1.2 1 0 0 1 1 1 1 Prefoldin subunit Atg14 PF10186.4 EWM29085.1 - 0.012 14.5 0.2 0.018 14.0 0.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Gp-FAR-1 PF05823.7 EWM29085.1 - 0.013 15.4 0.3 0.75 9.7 0.0 2.1 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF342 PF03961.8 EWM29085.1 - 0.016 13.6 0.2 0.039 12.3 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Mod_r PF07200.8 EWM29085.1 - 0.032 14.1 2.4 0.33 10.8 0.2 2.0 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TnpV PF14198.1 EWM29085.1 - 0.035 13.9 1.3 0.2 11.5 0.0 2.3 2 1 0 2 2 2 0 Transposon-encoded protein TnpV DUF2353 PF09789.4 EWM29085.1 - 0.036 13.3 5.0 0.085 12.1 3.6 1.4 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) ATG16 PF08614.6 EWM29085.1 - 0.048 13.4 0.6 0.083 12.7 0.4 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Sec2p PF06428.6 EWM29085.1 - 0.055 13.3 1.5 0.45 10.3 0.1 2.1 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Spc24 PF08286.6 EWM29085.1 - 0.058 13.0 1.3 2 8.1 0.1 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Prefoldin PF02996.12 EWM29085.1 - 0.086 12.4 2.0 7.7 6.2 0.2 2.3 2 0 0 2 2 2 0 Prefoldin subunit FTA4 PF13093.1 EWM29085.1 - 0.095 12.1 0.9 0.11 11.8 0.6 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Seryl_tRNA_N PF02403.17 EWM29085.1 - 0.29 11.1 4.1 1.2 9.2 0.2 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DivIVA PF05103.8 EWM29085.1 - 0.36 10.8 6.9 2.6 8.1 0.9 2.1 2 0 0 2 2 2 0 DivIVA protein TBPIP PF07106.8 EWM29085.1 - 0.37 10.3 3.1 3.2 7.2 0.2 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CCDC155 PF14662.1 EWM29085.1 - 0.39 10.2 5.8 1.9 8.0 0.5 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 NTR2 PF15458.1 EWM29085.1 - 0.39 9.8 5.9 0.14 11.4 0.3 2.1 2 1 0 2 2 2 0 Nineteen complex-related protein 2 IncA PF04156.9 EWM29085.1 - 0.52 9.8 6.0 4.6 6.8 4.2 1.9 1 1 0 1 1 1 0 IncA protein APG6 PF04111.7 EWM29085.1 - 0.97 8.4 5.7 0.53 9.2 0.4 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF4200 PF13863.1 EWM29085.1 - 1.5 8.7 7.1 5.9 6.8 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) bZIP_1 PF00170.16 EWM29085.1 - 3.6 7.6 8.3 3.5 7.6 1.0 2.6 2 1 0 2 2 2 0 bZIP transcription factor DivIC PF04977.10 EWM29085.1 - 5.4 6.5 7.8 5.9 6.4 0.3 2.6 2 1 1 3 3 3 0 Septum formation initiator adh_short PF00106.20 EWM29086.1 - 9.4e-29 100.4 5.6 1.2e-28 100.0 3.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EWM29086.1 - 4.8e-21 75.6 0.2 5.7e-21 75.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EWM29086.1 - 1.8e-10 40.7 3.9 2.5e-10 40.2 2.7 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EWM29086.1 - 3.4e-05 23.4 0.4 6.2e-05 22.5 0.3 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EWM29086.1 - 8.3e-05 21.4 0.1 0.00011 20.9 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.13 EWM29086.1 - 0.0022 17.6 0.2 0.0035 17.0 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Met_synt_B12 PF02965.12 EWM29086.1 - 0.054 12.6 0.2 0.08 12.1 0.1 1.2 1 0 0 1 1 1 0 Vitamin B12 dependent methionine synthase, activation domain SpoU_methylase PF00588.14 EWM29087.1 - 2.5e-26 92.2 0.0 3.5e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family WSC PF01822.14 EWM29088.1 - 9.5e-09 35.0 8.1 9.5e-09 35.0 5.6 2.3 2 0 0 2 2 2 1 WSC domain Lectin_C PF00059.16 EWM29088.1 - 0.0018 18.8 0.0 0.006 17.2 0.0 1.9 2 0 0 2 2 2 1 Lectin C-type domain DUF2844 PF11005.3 EWM29088.1 - 0.2 11.4 0.0 0.37 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2844) Nuf2 PF03800.9 EWM29090.1 - 8.7e-40 136.0 0.7 2.4e-39 134.6 0.5 1.8 1 0 0 1 1 1 1 Nuf2 family Seryl_tRNA_N PF02403.17 EWM29090.1 - 0.082 12.9 45.4 0.71 9.9 4.2 4.4 1 1 3 5 5 5 0 Seryl-tRNA synthetase N-terminal domain Herpes_U30 PF04523.8 EWM29090.1 - 1.2 6.4 11.4 0.099 10.0 2.9 2.0 1 1 0 2 2 2 0 Herpes virus tegument protein U30 Reo_sigmaC PF04582.7 EWM29090.1 - 2 7.4 7.0 18 4.3 0.2 3.0 1 1 1 3 3 3 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 EWM29090.1 - 4.3 5.6 28.1 0.2 10.0 3.4 2.6 1 1 2 3 3 3 0 AAA domain Fib_alpha PF08702.5 EWM29090.1 - 4.4 7.4 14.2 6.1 6.9 2.2 3.8 1 1 2 4 4 4 0 Fibrinogen alpha/beta chain family BLOC1_2 PF10046.4 EWM29090.1 - 7.2 6.8 15.1 3.9 7.6 1.4 4.0 3 2 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NAD_binding_5 PF07994.7 EWM29092.1 - 7.5e-109 363.7 0.0 9e-109 363.5 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 EWM29092.1 - 1.8e-47 159.8 0.1 3.5e-47 158.8 0.1 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase YCII PF03795.9 EWM29094.1 - 8.1e-13 48.3 0.0 1.8e-11 44.0 0.0 2.3 2 0 0 2 2 2 1 YCII-related domain FtsL PF04999.8 EWM29094.1 - 0.21 11.3 0.2 0.43 10.3 0.1 1.4 1 0 0 1 1 1 0 Cell division protein FtsL Nuc_sug_transp PF04142.10 EWM29095.1 - 1.9e-87 292.4 7.6 1.9e-87 292.4 5.3 1.4 2 0 0 2 2 2 1 Nucleotide-sugar transporter UAA PF08449.6 EWM29095.1 - 3.4e-10 39.3 13.4 4.8e-10 38.8 9.3 1.3 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EWM29095.1 - 1.3e-07 31.6 0.8 1.3e-07 31.6 0.6 3.3 2 1 1 3 3 3 1 EamA-like transporter family EmrE PF13536.1 EWM29095.1 - 1.4e-06 28.4 0.3 1.4e-06 28.4 0.2 3.4 3 1 1 4 4 4 1 Multidrug resistance efflux transporter TPT PF03151.11 EWM29095.1 - 5e-05 22.9 30.4 0.0011 18.6 3.2 2.4 2 1 0 2 2 2 2 Triose-phosphate Transporter family DUF4001 PF13165.1 EWM29095.1 - 0.28 10.8 1.7 0.66 9.6 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4001) DUF1230 PF06799.6 EWM29095.1 - 0.93 9.3 4.8 0.23 11.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1230) DUF486 PF04342.7 EWM29095.1 - 5.1 7.1 13.8 0.16 12.0 3.2 2.7 2 1 1 3 3 3 0 Protein of unknown function, DUF486 Citrate_synt PF00285.16 EWM29096.1 - 2.4e-23 82.4 0.1 1.6e-21 76.4 0.0 2.7 1 1 1 2 2 2 1 Citrate synthase Ligase_CoA PF00549.14 EWM29096.1 - 1.5e-15 57.0 0.0 6.5e-15 55.0 0.0 2.1 3 0 0 3 3 3 1 CoA-ligase ATP-grasp_2 PF08442.5 EWM29096.1 - 1.5e-09 37.5 0.0 2.7e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CoA_binding PF02629.14 EWM29096.1 - 1.8e-08 34.8 0.0 5.5e-08 33.2 0.0 2.0 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.1 EWM29096.1 - 0.00045 19.8 0.0 0.00097 18.7 0.0 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain ABC1 PF03109.11 EWM29098.1 - 1.5e-26 92.7 0.0 3.7e-26 91.4 0.0 1.7 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 EWM29098.1 - 1e-05 25.4 3.1 8.5e-05 22.3 0.4 2.7 3 0 0 3 3 3 1 Phosphotransferase enzyme family Tetraspannin PF00335.15 EWM29099.1 - 1.6e-07 30.8 18.1 4.7e-07 29.2 12.5 1.7 1 1 0 1 1 1 1 Tetraspanin family DUF778 PF05608.7 EWM29100.1 - 1.9e-30 105.5 4.0 3.2e-28 98.3 2.8 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF778) adh_short PF00106.20 EWM29101.1 - 3.1e-19 69.5 0.0 7.3e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EWM29101.1 - 8.5e-06 25.6 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EWM29101.1 - 1.8e-05 24.4 0.1 0.00015 21.5 0.0 2.0 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 EWM29101.1 - 0.0032 16.9 0.0 0.0047 16.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 EWM29101.1 - 0.087 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GSHPx PF00255.14 EWM29103.1 - 1.1e-39 134.1 0.3 1.5e-39 133.6 0.2 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 EWM29103.1 - 2.6e-05 23.8 0.1 3.6e-05 23.4 0.1 1.3 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EWM29103.1 - 0.00022 20.7 0.1 0.00041 19.9 0.1 1.5 1 1 0 1 1 1 1 Redoxin tRNA-synt_2 PF00152.15 EWM29104.1 - 6.6e-89 297.9 0.0 8.6e-89 297.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EWM29104.1 - 4.5e-17 61.6 0.3 8.3e-17 60.8 0.2 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EWM29104.1 - 0.00013 21.2 0.0 0.051 12.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) ORC5_C PF14630.1 EWM29106.1 - 1.1e-29 103.8 0.0 4.8e-29 101.6 0.0 2.1 2 1 0 2 2 2 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 EWM29106.1 - 1e-09 38.6 1.6 4.4e-09 36.5 1.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EWM29106.1 - 0.014 16.1 0.1 0.039 14.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EWM29106.1 - 0.017 14.8 0.1 0.06 13.0 0.1 2.0 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 EWM29106.1 - 0.03 14.4 0.0 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EWM29106.1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Daxx PF03344.10 EWM29106.1 - 2 6.7 16.4 0.064 11.7 7.3 1.4 2 0 0 2 2 2 0 Daxx Family SLBP_RNA_bind PF15247.1 EWM29107.1 - 5.8e-27 93.2 1.2 5.8e-27 93.2 0.8 1.9 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain SecE PF00584.15 EWM29108.1 - 1.6e-13 49.9 0.0 2.3e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex DEAD PF00270.24 EWM29109.1 - 2.8e-38 131.0 0.0 2.3e-37 128.0 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EWM29109.1 - 1.1e-26 92.5 0.0 8.8e-26 89.5 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SecA_DEAD PF07517.9 EWM29109.1 - 0.0036 16.6 0.1 0.0074 15.5 0.0 1.5 1 0 0 1 1 1 1 SecA DEAD-like domain zf-CCHC PF00098.18 EWM29109.1 - 0.016 15.0 2.0 0.016 15.0 1.4 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 EWM29109.1 - 0.26 11.0 1.4 0.62 9.7 1.0 1.6 1 0 0 1 1 1 0 Zinc knuckle OxoDH_E1alpha_N PF12573.3 EWM29110.1 - 0.19 11.2 3.3 0.32 10.5 0.1 2.6 2 0 0 2 2 2 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal Amidase PF01425.16 EWM29112.1 - 1.2e-61 208.9 0.0 1.3e-61 208.8 0.0 1.0 1 0 0 1 1 1 1 Amidase ArfGap PF01412.13 EWM29114.1 - 4.9e-15 55.3 0.3 7.3e-15 54.7 0.2 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF2451 PF10474.4 EWM29115.1 - 1.3e-37 129.8 0.0 4.2e-37 128.1 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) DUF2450 PF10475.4 EWM29115.1 - 1.2e-10 40.7 3.5 2.1e-10 40.0 2.4 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) TPT PF03151.11 EWM29116.1 - 4.7e-21 75.0 10.2 4.7e-21 75.0 7.0 2.4 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EWM29116.1 - 0.0018 18.3 8.3 0.0018 18.3 5.7 3.6 1 1 2 4 4 4 1 EamA-like transporter family DUF2819 PF10995.3 EWM29116.1 - 0.045 12.5 0.2 0.061 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2819) SyrA PF11089.3 EWM29116.1 - 0.1 12.4 4.7 0.065 13.0 1.2 2.3 2 0 0 2 2 2 0 Exopolysaccharide production repressor DUF4231 PF14015.1 EWM29116.1 - 1.5 8.8 5.2 0.88 9.5 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) EmrE PF13536.1 EWM29116.1 - 6.2 7.0 27.1 2 8.6 3.8 3.8 1 1 3 4 4 4 0 Multidrug resistance efflux transporter TPT PF03151.11 EWM29117.1 - 6.1e-21 74.6 10.2 6.1e-21 74.6 7.0 2.4 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EWM29117.1 - 0.0023 17.9 8.3 0.0023 17.9 5.8 3.6 1 1 2 4 4 4 1 EamA-like transporter family SyrA PF11089.3 EWM29117.1 - 0.016 14.9 1.8 0.076 12.8 1.2 2.2 1 0 0 1 1 1 0 Exopolysaccharide production repressor DUF2819 PF10995.3 EWM29117.1 - 0.054 12.2 0.2 0.077 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2819) GXWXG PF14231.1 EWM29119.1 - 0.008 15.8 0.9 0.022 14.4 0.7 1.9 1 1 0 1 1 1 1 GXWXG protein tRNA-synt_1 PF00133.17 EWM29120.1 - 4.3e-193 642.6 0.0 5.9e-193 642.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EWM29120.1 - 2.1e-31 108.7 0.0 3.8e-31 107.9 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EWM29120.1 - 6.6e-22 77.7 0.0 5.9e-12 44.9 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EWM29120.1 - 0.00046 19.4 0.0 0.51 9.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.1 EWM29120.1 - 0.0054 16.0 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 zf-FPG_IleRS PF06827.9 EWM29120.1 - 0.2 11.3 3.4 0.53 9.9 2.3 1.8 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS tRNA-synt_1d PF00750.14 EWM29120.1 - 0.26 10.0 0.0 8 5.1 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (R) Glyco_hydro_3 PF00933.16 EWM29122.1 - 2.9e-67 226.7 0.0 4e-67 226.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EWM29122.1 - 4.5e-39 134.3 0.0 7e-39 133.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EWM29122.1 - 3.3e-11 42.9 0.0 6.4e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain zf-BED PF02892.10 EWM29123.1 - 0.03 14.0 7.1 0.059 13.1 4.9 1.5 1 0 0 1 1 1 0 BED zinc finger adh_short PF00106.20 EWM29124.1 - 5.7e-13 49.1 0.0 1.1e-10 41.6 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EWM29124.1 - 0.011 15.4 0.0 2.9 7.5 0.0 2.2 2 0 0 2 2 2 0 KR domain Sec10 PF07393.6 EWM29126.1 - 6.1e-47 160.2 0.9 1.6e-19 69.6 0.0 4.0 4 0 0 4 4 4 4 Exocyst complex component Sec10 RINT1_TIP1 PF04437.8 EWM29126.1 - 0.016 13.7 0.0 0.033 12.7 0.0 1.5 1 0 0 1 1 1 0 RINT-1 / TIP-1 family RNA_pol_Rpb2_3 PF04565.11 EWM29126.1 - 0.13 12.0 0.0 0.52 10.0 0.0 2.0 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 3 BT1 PF03092.11 EWM29128.1 - 6.3e-50 170.1 12.1 8.6e-50 169.6 8.4 1.1 1 0 0 1 1 1 1 BT1 family MFS_1 PF07690.11 EWM29128.1 - 7.8e-14 51.1 26.6 1.4e-10 40.4 14.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 EWM29128.1 - 0.0025 16.3 19.6 0.002 16.7 11.5 2.0 1 1 1 2 2 2 1 Vacuole effluxer Atg22 like Tubulin PF00091.20 EWM29130.1 - 8.4e-74 248.0 0.0 1.4e-73 247.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EWM29130.1 - 4e-49 165.8 0.3 8.6e-49 164.7 0.2 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EWM29130.1 - 2.4e-06 27.6 0.0 6.3e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.1 EWM29130.1 - 0.076 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Tubulin like Sed5p PF11416.3 EWM29130.1 - 0.14 11.6 0.8 0.29 10.6 0.6 1.5 1 0 0 1 1 1 0 Integral membrane protein Sed5p RhoGAP PF00620.22 EWM29131.1 - 1.6e-21 76.4 0.1 3.6e-21 75.3 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.18 EWM29131.1 - 5.6e-21 75.5 0.0 8.5e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Metallophos PF00149.23 EWM29131.1 - 0.091 12.1 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase MCM PF00493.18 EWM29132.1 - 3.3e-78 262.8 0.0 5.7e-71 239.0 0.0 2.1 2 0 0 2 2 2 2 MCM2/3/5 family MCM_N PF14551.1 EWM29132.1 - 6.6e-13 49.2 0.0 1.2e-12 48.4 0.0 1.4 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EWM29132.1 - 5.4e-09 35.5 0.1 1.1e-05 24.6 0.0 2.6 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EWM29132.1 - 1.1e-06 28.3 0.0 2.5e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 EWM29132.1 - 0.0083 15.6 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_19 PF13245.1 EWM29132.1 - 0.037 13.7 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 EWM29132.1 - 0.092 12.7 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain zf-tcix PF14952.1 EWM29132.1 - 0.11 11.8 0.2 0.11 11.8 0.1 2.1 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding COX16 PF14138.1 EWM29133.1 - 1.5e-12 47.5 1.8 2.8e-11 43.4 1.3 2.0 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 EMP24_GP25L PF01105.19 EWM29134.1 - 1.8e-33 115.7 0.0 2.2e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD ArgK PF03308.11 EWM29135.1 - 1.8e-80 269.5 0.0 5.4e-79 264.7 0.0 2.0 2 0 0 2 2 2 1 ArgK protein cobW PF02492.14 EWM29135.1 - 2.1e-10 40.3 0.0 5.3e-10 39.0 0.0 1.7 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 EWM29135.1 - 3.4e-05 24.6 0.1 0.00025 21.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.12 EWM29135.1 - 0.00013 21.6 0.0 0.00037 20.1 0.0 1.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein CbiA PF01656.18 EWM29135.1 - 0.0007 19.0 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 EWM29135.1 - 0.003 17.2 0.0 0.0067 16.1 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EWM29135.1 - 0.0033 17.7 0.1 0.011 15.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EWM29135.1 - 0.0048 16.9 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EWM29135.1 - 0.0051 16.2 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain KAP_NTPase PF07693.9 EWM29135.1 - 0.0063 15.5 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain MMR_HSR1 PF01926.18 EWM29135.1 - 0.0075 16.2 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EWM29135.1 - 0.0085 15.2 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 EWM29135.1 - 0.009 15.8 0.2 0.026 14.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EWM29135.1 - 0.015 15.5 0.0 0.033 14.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.13 EWM29135.1 - 0.023 14.1 0.0 0.068 12.6 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.1 EWM29135.1 - 0.026 14.1 0.0 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EWM29135.1 - 0.028 14.5 0.1 0.1 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 EWM29135.1 - 0.032 13.6 0.0 3.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_19 PF13245.1 EWM29135.1 - 0.037 13.7 0.1 0.14 11.9 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain KTI12 PF08433.5 EWM29135.1 - 0.039 13.1 0.1 0.13 11.4 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 NTPase_1 PF03266.10 EWM29135.1 - 0.044 13.4 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA PF00004.24 EWM29135.1 - 0.064 13.4 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 EWM29135.1 - 0.094 13.2 0.1 0.35 11.3 0.0 1.9 2 0 0 2 2 1 0 Miro-like protein AAA_23 PF13476.1 EWM29135.1 - 0.1 12.9 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EWM29135.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 EWM29135.1 - 0.14 11.6 0.1 0.22 10.9 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_24 PF13479.1 EWM29135.1 - 0.14 11.6 0.1 0.33 10.4 0.1 1.8 2 1 0 2 2 2 0 AAA domain DUF2256 PF10013.4 EWM29135.1 - 0.38 10.5 5.7 0.92 9.3 0.8 2.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) EMP70 PF02990.11 EWM29136.1 - 1e-197 657.7 7.0 1.3e-197 657.3 4.8 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 DUF4229 PF14012.1 EWM29136.1 - 0.063 13.1 0.0 0.063 13.1 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF4229) MFS_1 PF07690.11 EWM29137.1 - 8.1e-30 103.7 9.1 1.1e-29 103.2 6.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EWM29137.1 - 1.5e-11 43.5 7.5 2e-11 43.1 5.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EWM29137.1 - 5.3e-05 21.6 1.6 6.7e-05 21.2 1.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ATG22 PF11700.3 EWM29137.1 - 0.0079 14.7 12.7 0.11 10.9 8.0 2.2 2 1 0 2 2 2 1 Vacuole effluxer Atg22 like MFS_3 PF05977.8 EWM29137.1 - 0.099 10.7 4.6 0.14 10.2 3.2 1.1 1 0 0 1 1 1 0 Transmembrane secretion effector CLTH PF10607.4 EWM29139.1 - 3.6e-24 85.0 0.0 5e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain U-box PF04564.10 EWM29139.1 - 0.0067 16.3 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-RING_UBOX PF13445.1 EWM29139.1 - 0.15 11.7 0.9 0.41 10.4 0.0 2.2 2 0 0 2 2 2 0 RING-type zinc-finger DUF2183 PF09949.4 EWM29140.1 - 5.4e-05 23.0 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) PGK PF00162.14 EWM29140.1 - 0.55 8.7 0.1 0.86 8.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoglycerate kinase DUF2183 PF09949.4 EWM29141.1 - 5.1e-05 23.1 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) PGK PF00162.14 EWM29141.1 - 0.51 8.8 0.1 0.81 8.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoglycerate kinase HypA PF01155.14 EWM29143.1 - 0.12 12.0 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family S1 PF00575.18 EWM29144.1 - 2.2e-13 50.1 0.0 6.2e-08 32.6 0.0 2.6 2 0 0 2 2 2 2 S1 RNA binding domain zf-CCHC_5 PF14787.1 EWM29145.1 - 1 8.8 3.3 12 5.5 0.2 2.6 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger Clathrin PF00637.15 EWM29146.1 - 3.9e-187 613.3 32.5 3.1e-31 107.8 1.2 8.3 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 EWM29146.1 - 3.9e-27 93.9 0.2 3.9e-27 93.9 0.2 3.7 5 0 0 5 5 5 1 Clathrin-H-link Clathrin_propel PF01394.15 EWM29146.1 - 9.8e-13 47.4 0.3 0.083 13.2 0.0 5.9 5 0 0 5 5 5 3 Clathrin propeller repeat TPR_2 PF07719.12 EWM29146.1 - 4.6e-05 23.0 3.0 1.5 8.9 0.0 6.3 5 0 0 5 5 5 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.9 EWM29146.1 - 0.00034 19.5 1.3 0.099 11.4 0.1 3.2 4 0 0 4 4 4 2 Coatomer WD associated region TPR_14 PF13428.1 EWM29146.1 - 0.00078 19.8 11.6 6.8 7.6 0.0 9.8 10 1 1 11 11 10 1 Tetratricopeptide repeat Clathrin-link PF09268.5 EWM29146.1 - 0.0025 16.7 0.1 0.0087 15.0 0.1 2.0 1 0 0 1 1 1 1 Clathrin, heavy-chain linker TPR_8 PF13181.1 EWM29146.1 - 0.0078 15.9 5.0 3.2 7.7 0.1 6.3 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.23 EWM29146.1 - 0.053 13.1 6.1 1 9.0 0.2 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 EWM29146.1 - 0.3 11.2 10.7 0.073 13.2 0.3 4.4 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EWM29146.1 - 0.54 10.8 4.8 9.7 6.9 0.1 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat HCO3_cotransp PF00955.16 EWM29147.1 - 2.5e-99 333.2 11.4 2.8e-53 181.3 0.9 2.2 1 1 1 2 2 2 2 HCO3- transporter family DUF221 PF02714.10 EWM29149.1 - 6.2e-69 232.3 25.3 9.3e-69 231.7 17.5 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EWM29149.1 - 1.8e-32 112.0 0.2 1.8e-32 112.0 0.1 2.8 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EWM29149.1 - 1.7e-11 44.4 0.0 3e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) NTP_transf_2 PF01909.18 EWM29150.1 - 9.7e-05 22.6 0.0 0.00023 21.4 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 EWM29150.1 - 0.0052 16.6 0.0 0.019 14.8 0.0 2.1 1 0 0 1 1 1 1 Cid1 family poly A polymerase LON PF02190.11 EWM29151.1 - 1.3e-13 51.1 0.0 1.7e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-RING_2 PF13639.1 EWM29151.1 - 1.6e-08 34.2 11.6 4e-08 32.9 8.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EWM29151.1 - 1.9e-07 30.9 11.2 4.8e-07 29.7 7.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EWM29151.1 - 2.5e-07 30.2 12.3 5.2e-07 29.2 8.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EWM29151.1 - 2.9e-07 30.0 9.3 2.9e-07 30.0 6.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EWM29151.1 - 3.2e-06 26.7 9.7 6.5e-06 25.7 6.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EWM29151.1 - 0.002 17.7 4.4 0.002 17.7 3.1 1.8 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EWM29151.1 - 0.0042 17.1 2.1 0.011 15.7 1.5 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EWM29151.1 - 0.0042 16.9 10.7 0.013 15.3 7.4 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EWM29151.1 - 0.011 15.3 7.3 0.036 13.7 5.1 1.9 1 1 0 1 1 1 0 RING-type zinc-finger SHMT PF00464.14 EWM29153.1 - 2.6e-177 589.1 0.0 3e-177 588.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 EWM29153.1 - 9e-05 21.7 0.0 0.00023 20.4 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Macro PF01661.16 EWM29153.1 - 0.0081 16.0 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 Macro domain HTH_26 PF13443.1 EWM29153.1 - 0.12 12.6 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain SHMT PF00464.14 EWM29154.1 - 2.9e-177 589.0 0.0 3.4e-177 588.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 EWM29154.1 - 9.8e-05 21.6 0.0 0.00024 20.3 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Macro PF01661.16 EWM29154.1 - 0.0069 16.2 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 Macro domain HTH_26 PF13443.1 EWM29154.1 - 0.12 12.5 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Epimerase PF01370.16 EWM29155.1 - 1.7e-57 194.5 0.0 2.3e-57 194.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EWM29155.1 - 2.7e-19 68.9 0.0 3.7e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EWM29155.1 - 2.1e-15 56.3 0.0 4.7e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EWM29155.1 - 7.6e-14 51.2 0.0 4.4e-13 48.7 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EWM29155.1 - 2e-12 46.5 0.0 3e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EWM29155.1 - 3.3e-11 43.3 0.8 9.4e-11 41.9 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EWM29155.1 - 2.2e-08 33.9 0.4 5.6e-08 32.6 0.3 1.6 1 1 0 1 1 1 1 KR domain Epimerase_Csub PF13950.1 EWM29155.1 - 6.1e-05 22.8 0.0 0.00019 21.3 0.0 1.9 1 1 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit NAD_binding_10 PF13460.1 EWM29155.1 - 0.00092 19.2 0.1 0.0047 16.9 0.1 2.1 1 1 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 EWM29155.1 - 0.1 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Nop14 PF04147.7 EWM29157.1 - 0.01 13.7 1.2 0.012 13.5 0.8 1.0 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EWM29157.1 - 0.14 10.6 5.0 0.17 10.3 3.5 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 EWM29157.1 - 0.88 7.5 4.6 1.2 7.1 3.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Tcf25 PF04910.9 EWM29158.1 - 7.5e-48 163.3 0.0 9.6e-48 162.9 0.0 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_10 PF13374.1 EWM29158.1 - 0.034 14.0 1.0 0.093 12.6 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EWM29158.1 - 0.066 13.1 0.3 0.22 11.4 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 EWM29158.1 - 0.35 11.5 2.5 0.65 10.7 0.4 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Pro_isomerase PF00160.16 EWM29161.1 - 3.8e-39 134.3 0.0 6.7e-39 133.5 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 EWM29161.1 - 6.7e-16 57.6 0.1 1.2e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM29161.1 - 4.3e-11 42.6 0.0 1e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM29161.1 - 2.1e-09 37.0 0.0 4.7e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MTHFR PF02219.12 EWM29162.1 - 7.7e-105 350.0 0.0 1.2e-104 349.5 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase UQ_con PF00179.21 EWM29163.1 - 3.1e-51 172.4 0.0 3.5e-51 172.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EWM29163.1 - 9.6e-05 22.1 0.0 0.00012 21.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EWM29163.1 - 0.0015 18.4 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EWM29163.1 - 0.049 13.3 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 UEV domain AAA PF00004.24 EWM29164.1 - 3.3e-13 49.9 0.1 3.2e-12 46.8 0.0 2.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EWM29164.1 - 0.00026 21.1 2.7 0.13 12.3 0.2 3.6 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.9 EWM29164.1 - 0.00051 19.7 0.6 0.039 13.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EWM29164.1 - 0.0018 17.5 0.9 0.08 12.0 0.0 2.8 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI ResIII PF04851.10 EWM29164.1 - 0.0074 16.1 0.1 0.02 14.7 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 EWM29164.1 - 0.0095 15.3 0.9 0.038 13.3 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EWM29164.1 - 0.011 15.4 0.2 0.032 13.9 0.2 1.8 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 EWM29164.1 - 0.014 14.8 0.1 0.04 13.3 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.1 EWM29164.1 - 0.044 13.3 0.3 0.4 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EWM29164.1 - 0.06 13.2 2.6 0.068 13.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EWM29164.1 - 0.077 12.8 0.0 0.077 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EWM29164.1 - 0.078 13.2 0.1 0.078 13.2 0.1 2.0 2 0 0 2 2 2 0 AAA domain Zot PF05707.7 EWM29164.1 - 0.094 12.1 0.0 13 5.1 0.0 2.6 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) APS_kinase PF01583.15 EWM29164.1 - 0.095 12.3 0.6 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase Sigma54_activat PF00158.21 EWM29164.1 - 0.11 11.9 0.5 1.3 8.4 0.1 2.4 2 1 0 2 2 1 0 Sigma-54 interaction domain AAA_17 PF13207.1 EWM29164.1 - 0.19 12.5 4.9 0.051 14.3 0.6 2.3 2 2 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EWM29164.1 - 0.27 11.2 4.5 0.37 10.7 0.0 2.8 2 1 1 3 3 3 0 AAA ATPase domain PRK PF00485.13 EWM29164.1 - 0.29 10.6 2.2 1.9 8.0 0.0 2.6 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family AAA_30 PF13604.1 EWM29164.1 - 0.39 10.2 5.7 0.58 9.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain SKIP_SNW PF02731.10 EWM29164.1 - 0.42 10.0 5.2 0.68 9.3 3.6 1.3 1 0 0 1 1 1 0 SKIP/SNW domain AAA PF00004.24 EWM29165.1 - 3.3e-13 49.9 0.1 3.2e-12 46.8 0.0 2.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EWM29165.1 - 0.00026 21.1 2.7 0.13 12.3 0.2 3.6 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.9 EWM29165.1 - 0.00051 19.7 0.6 0.039 13.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EWM29165.1 - 0.0018 17.5 0.9 0.08 12.0 0.0 2.8 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI ResIII PF04851.10 EWM29165.1 - 0.0074 16.1 0.1 0.02 14.7 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 EWM29165.1 - 0.0095 15.3 0.9 0.038 13.3 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EWM29165.1 - 0.011 15.4 0.2 0.032 13.9 0.2 1.8 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 EWM29165.1 - 0.014 14.8 0.1 0.04 13.3 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.1 EWM29165.1 - 0.044 13.3 0.3 0.4 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EWM29165.1 - 0.06 13.2 2.6 0.068 13.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EWM29165.1 - 0.077 12.8 0.0 0.077 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EWM29165.1 - 0.078 13.2 0.1 0.078 13.2 0.1 2.0 2 0 0 2 2 2 0 AAA domain Zot PF05707.7 EWM29165.1 - 0.094 12.1 0.0 13 5.1 0.0 2.6 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) APS_kinase PF01583.15 EWM29165.1 - 0.095 12.3 0.6 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase Sigma54_activat PF00158.21 EWM29165.1 - 0.11 11.9 0.5 1.3 8.4 0.1 2.4 2 1 0 2 2 1 0 Sigma-54 interaction domain AAA_17 PF13207.1 EWM29165.1 - 0.19 12.5 4.9 0.051 14.3 0.6 2.3 2 2 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EWM29165.1 - 0.27 11.2 4.5 0.37 10.7 0.0 2.8 2 1 1 3 3 3 0 AAA ATPase domain PRK PF00485.13 EWM29165.1 - 0.29 10.6 2.2 1.9 8.0 0.0 2.6 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family AAA_30 PF13604.1 EWM29165.1 - 0.39 10.2 5.7 0.58 9.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain SKIP_SNW PF02731.10 EWM29165.1 - 0.42 10.0 5.2 0.68 9.3 3.6 1.3 1 0 0 1 1 1 0 SKIP/SNW domain TPR_16 PF13432.1 EWM29167.1 - 7.6e-55 182.5 11.7 1.8e-06 28.4 0.4 11.2 9 2 0 11 11 11 9 Tetratricopeptide repeat TPR_11 PF13414.1 EWM29167.1 - 1.1e-53 178.7 6.3 6.9e-07 28.8 0.0 11.8 7 3 3 12 12 12 10 TPR repeat TPR_2 PF07719.12 EWM29167.1 - 3.1e-49 160.9 18.3 0.00093 18.9 0.0 17.5 19 0 0 19 19 18 12 Tetratricopeptide repeat TPR_14 PF13428.1 EWM29167.1 - 4.6e-49 160.3 23.3 0.00012 22.4 0.0 16.5 5 5 12 17 17 17 10 Tetratricopeptide repeat TPR_19 PF14559.1 EWM29167.1 - 2e-44 149.7 3.7 0.00037 20.7 0.0 11.0 6 3 4 12 12 12 10 Tetratricopeptide repeat TPR_12 PF13424.1 EWM29167.1 - 4.7e-39 132.1 11.0 7.2e-06 25.8 0.2 10.9 9 4 2 11 11 10 6 Tetratricopeptide repeat TPR_17 PF13431.1 EWM29167.1 - 1.1e-34 115.7 0.4 0.0094 16.0 0.0 17.0 18 0 0 18 18 18 4 Tetratricopeptide repeat TPR_7 PF13176.1 EWM29167.1 - 4.4e-27 91.6 14.3 0.0097 15.6 0.0 14.5 14 1 1 15 15 14 4 Tetratricopeptide repeat TPR_1 PF00515.23 EWM29167.1 - 2.5e-24 83.8 2.7 0.0079 15.7 0.0 13.0 14 0 0 14 14 12 3 Tetratricopeptide repeat TPR_8 PF13181.1 EWM29167.1 - 3.3e-22 76.5 2.0 0.0093 15.6 0.0 12.6 14 0 0 14 14 13 3 Tetratricopeptide repeat Suf PF05843.9 EWM29167.1 - 7.9e-17 61.8 2.0 0.0013 18.4 0.0 6.9 5 3 2 7 7 7 5 Suppressor of forked protein (Suf) TPR_6 PF13174.1 EWM29167.1 - 2.6e-12 46.3 21.9 0.38 11.3 0.0 14.1 15 0 0 15 15 14 1 Tetratricopeptide repeat TPR_15 PF13429.1 EWM29167.1 - 1.8e-11 43.6 11.0 0.017 14.2 0.0 7.8 2 2 3 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 EWM29167.1 - 2.2e-08 34.0 0.9 7.7 6.7 0.0 7.0 5 1 2 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR_1 PF12854.2 EWM29167.1 - 8.6e-08 31.5 15.1 3.5 7.1 0.0 9.4 10 0 0 10 10 10 2 PPR repeat Coatomer_E PF04733.9 EWM29167.1 - 1e-07 31.5 0.4 0.038 13.1 0.0 5.1 5 1 0 5 5 5 2 Coatomer epsilon subunit TPR_9 PF13371.1 EWM29167.1 - 1.3e-07 31.3 17.5 0.015 15.1 0.0 6.8 6 3 2 8 8 7 2 Tetratricopeptide repeat TPR_10 PF13374.1 EWM29167.1 - 3.1e-06 26.9 27.0 1.2 9.1 0.3 10.4 12 0 0 12 12 11 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EWM29167.1 - 3.4e-05 23.6 3.5 42 3.9 0.0 8.0 7 2 0 8 8 8 0 Mad3/BUB1 homology region 1 PPR PF01535.15 EWM29167.1 - 4.7e-05 23.0 30.3 2.9 8.0 0.1 11.3 15 0 0 15 15 9 2 PPR repeat NARP1 PF12569.3 EWM29167.1 - 0.00022 20.1 6.8 0.18 10.5 0.0 4.7 4 1 0 5 5 5 2 NMDA receptor-regulated protein 1 TPR_4 PF07721.9 EWM29167.1 - 0.00023 21.2 29.1 0.91 10.1 0.3 10.9 12 0 0 12 12 9 1 Tetratricopeptide repeat TPR_3 PF07720.7 EWM29167.1 - 0.00036 20.2 0.0 1e+02 2.8 0.0 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_21 PF09976.4 EWM29167.1 - 0.00095 19.1 9.7 2.4 8.0 0.0 5.8 4 2 2 6 6 6 1 Tetratricopeptide repeat PPR_3 PF13812.1 EWM29167.1 - 0.0015 18.6 18.0 52 4.4 0.0 11.1 12 1 1 13 13 10 0 Pentatricopeptide repeat domain Dimer_Tnp_Tn5 PF02281.11 EWM29167.1 - 0.013 15.5 1.2 14 5.8 0.1 4.0 4 0 0 4 4 3 0 Transposase Tn5 dimerisation domain DUF3808 PF10300.4 EWM29167.1 - 0.048 12.2 0.1 23 3.3 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3808) PPR_2 PF13041.1 EWM29167.1 - 0.057 13.3 9.1 51 3.9 0.0 8.1 9 0 0 9 9 7 0 PPR repeat family Apc5 PF12862.2 EWM29167.1 - 0.2 11.5 2.6 12 5.7 0.3 4.1 3 1 1 4 4 3 0 Anaphase-promoting complex subunit 5 HemY_N PF07219.8 EWM29167.1 - 1.6 8.3 7.1 66 3.1 0.0 5.6 5 3 2 7 7 6 0 HemY protein N-terminus Isochorismatase PF00857.15 EWM29168.1 - 0.00056 19.8 0.0 0.43 10.4 0.0 2.5 2 0 0 2 2 2 2 Isochorismatase family PAS_9 PF13426.1 EWM29169.1 - 1.5e-21 76.7 0.1 5.5e-21 74.8 0.0 1.9 2 0 0 2 2 2 1 PAS domain bZIP_2 PF07716.10 EWM29169.1 - 1.9e-07 30.7 10.7 1.9e-07 30.7 7.4 1.7 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 EWM29169.1 - 7.9e-07 28.9 9.4 1.6e-06 27.9 6.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor PAS PF00989.19 EWM29169.1 - 5.8e-06 26.0 0.0 1.3e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 EWM29169.1 - 0.00032 20.7 0.0 0.0006 19.8 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.6 EWM29169.1 - 0.0048 16.9 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.1 EWM29169.1 - 0.039 13.8 0.0 0.15 11.9 0.0 2.1 1 1 0 1 1 1 0 PAS domain bZIP_Maf PF03131.12 EWM29169.1 - 0.1 12.9 9.6 0.087 13.1 3.3 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor Tox-MPTase5 PF15641.1 EWM29170.1 - 0.12 12.4 0.1 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Metallopeptidase toxin 5 CRAL_TRIO PF00650.15 EWM29171.1 - 5.2e-17 61.7 0.2 7.7e-17 61.2 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO PF00650.15 EWM29173.1 - 3.5e-17 62.3 0.2 5e-17 61.8 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain Lipase_GDSL PF00657.17 EWM29174.1 - 4.1e-16 59.5 0.0 7.6e-16 58.6 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EWM29174.1 - 1.8e-10 41.2 0.0 3.1e-10 40.4 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Pkinase PF00069.20 EWM29175.1 - 6.7e-71 238.4 0.0 1.2e-70 237.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM29175.1 - 1e-32 113.2 0.0 3.1e-32 111.6 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase FHA PF00498.21 EWM29175.1 - 8.8e-16 57.7 0.6 2.3e-15 56.4 0.1 2.0 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.1 EWM29175.1 - 2.5e-09 36.5 0.0 5.6e-09 35.3 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EWM29175.1 - 1.5e-05 24.1 0.0 2.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EWM29175.1 - 0.016 14.5 0.1 0.042 13.1 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 EWM29175.1 - 0.034 12.9 0.1 0.051 12.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 EWM29175.1 - 0.081 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Branch PF02485.16 EWM29176.1 - 0.0036 16.4 0.0 0.034 13.3 0.0 2.0 1 1 0 1 1 1 1 Core-2/I-Branching enzyme HA2 PF04408.18 EWM29177.1 - 1.6e-24 85.8 0.1 2.6e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EWM29177.1 - 1.1e-22 79.9 0.0 1.9e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EWM29177.1 - 3.8e-10 39.4 0.0 9.4e-10 38.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EWM29177.1 - 1.5e-06 27.7 0.0 2.8e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EWM29177.1 - 1.8e-05 24.8 0.0 6e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EWM29177.1 - 0.0047 17.2 0.0 0.016 15.4 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_30 PF13604.1 EWM29177.1 - 0.0056 16.2 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EWM29177.1 - 0.013 14.4 0.0 0.031 13.1 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein KaiC PF06745.8 EWM29177.1 - 0.014 14.5 0.0 0.079 12.0 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_29 PF13555.1 EWM29177.1 - 0.024 14.1 0.0 0.057 12.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ResIII PF04851.10 EWM29177.1 - 0.075 12.8 0.0 10 5.9 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Zeta_toxin PF06414.7 EWM29177.1 - 0.13 11.3 0.0 0.35 9.9 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin DUF258 PF03193.11 EWM29177.1 - 0.16 11.1 0.0 0.31 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 CCDC155 PF14662.1 EWM29178.1 - 0.0048 16.5 20.7 0.43 10.1 11.2 2.3 2 0 0 2 2 2 2 Coiled-coil region of CCDC155 AAA_13 PF13166.1 EWM29178.1 - 0.28 9.5 7.5 0.3 9.4 5.2 1.2 1 0 0 1 1 1 0 AAA domain Prominin PF05478.6 EWM29178.1 - 0.29 8.5 6.0 2 5.8 0.0 2.1 2 0 0 2 2 2 0 Prominin HCMV_UL139 PF12507.3 EWM29178.1 - 0.32 11.1 4.7 0.21 11.7 1.7 1.8 1 1 1 2 2 2 0 Human Cytomegalovirus UL139 protein FeoC PF09012.5 EWM29178.1 - 0.55 9.9 3.5 0.7 9.6 0.0 2.4 2 0 0 2 2 2 0 FeoC like transcriptional regulator bZIP_1 PF00170.16 EWM29178.1 - 0.69 9.9 19.2 0.23 11.4 0.3 4.1 2 1 4 6 6 6 0 bZIP transcription factor DUF87 PF01935.12 EWM29178.1 - 1.4 8.6 8.8 2 8.1 4.9 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 V_ATPase_I PF01496.14 EWM29178.1 - 1.6 6.4 8.8 2 6.1 6.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nnf1 PF03980.9 EWM29178.1 - 1.7 8.6 15.0 1.2 9.1 7.2 2.4 2 1 0 2 2 2 0 Nnf1 Fib_alpha PF08702.5 EWM29178.1 - 3.5 7.7 9.7 71 3.4 0.0 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4140 PF13600.1 EWM29178.1 - 7.9 6.9 15.3 29 5.1 0.1 3.2 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) MFS_1 PF07690.11 EWM29180.1 - 1.4e-08 33.8 39.6 1.4e-08 33.8 27.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EWM29180.1 - 2.6e-08 32.7 30.5 2.9e-07 29.2 21.2 2.6 1 1 0 1 1 1 1 MFS/sugar transport protein Myb_Cef PF11831.3 EWM29181.1 - 6.8e-35 120.3 0.1 6.8e-35 120.3 0.0 3.5 4 0 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 EWM29181.1 - 4.7e-20 71.3 4.8 2.7e-09 36.9 0.1 4.3 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EWM29181.1 - 5.6e-17 61.5 4.1 7.8e-13 48.3 2.0 3.1 2 1 1 3 3 3 2 Myb-like DNA-binding domain Dala_Dala_lig_N PF01820.16 EWM29181.1 - 1.1 9.5 4.0 1.4 9.2 0.0 2.9 3 0 0 3 3 3 0 D-ala D-ala ligase N-terminus TPT PF03151.11 EWM29182.1 - 8.1e-28 96.9 0.4 8.1e-28 96.9 0.2 2.1 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EWM29182.1 - 1.7e-06 27.1 14.9 0.00056 18.9 0.4 2.2 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.15 EWM29182.1 - 0.0021 18.0 11.9 0.0021 18.0 8.2 2.6 2 1 0 2 2 2 1 EamA-like transporter family C2 PF00168.25 EWM29183.1 - 0.00016 21.4 0.0 0.00031 20.5 0.0 1.4 1 0 0 1 1 1 1 C2 domain FixQ PF05545.6 EWM29183.1 - 0.16 11.6 0.7 0.34 10.5 0.5 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ NIF PF03031.13 EWM29185.1 - 1.2e-47 161.5 0.0 4.4e-47 159.6 0.0 1.8 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Sld5 PF05916.6 EWM29187.1 - 3.9e-07 30.3 0.0 2.8e-06 27.5 0.1 1.9 2 0 0 2 2 2 1 GINS complex protein FliT PF05400.8 EWM29187.1 - 0.01 16.2 0.1 0.021 15.2 0.1 1.4 1 0 0 1 1 1 0 Flagellar protein FliT FOP_dimer PF09398.5 EWM29188.1 - 8.9e-06 25.6 0.0 7.3e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 FOP N terminal dimerisation domain Patatin PF01734.17 EWM29189.1 - 3.9e-22 79.2 0.1 7.5e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase cNMP_binding PF00027.24 EWM29189.1 - 1.2e-20 73.0 0.0 1.5e-10 40.6 0.0 5.0 4 2 0 4 4 4 3 Cyclic nucleotide-binding domain ATP12 PF07542.6 EWM29190.1 - 7.8e-29 100.1 0.0 1.3e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein Asparaginase PF00710.15 EWM29191.1 - 2.1e-94 315.9 0.0 2.3e-94 315.7 0.0 1.0 1 0 0 1 1 1 1 Asparaginase Peptidase_M20 PF01546.23 EWM29192.1 - 3.4e-26 91.9 0.0 2.3e-25 89.1 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EWM29192.1 - 2.6e-15 56.1 0.0 5.1e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Inhibitor_I69 PF13734.1 EWM29192.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Spi protease inhibitor PALP PF00291.20 EWM29194.1 - 4e-70 236.4 1.9 4.6e-70 236.2 1.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PAP_fibrillin PF04755.7 EWM29195.1 - 2.3e-05 24.2 0.0 0.024 14.3 0.0 2.3 2 0 0 2 2 2 2 PAP_fibrillin Pkinase PF00069.20 EWM29196.1 - 3.6e-72 242.6 0.0 4.5e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM29196.1 - 4.1e-33 114.5 0.0 6e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH_8 PF15409.1 EWM29196.1 - 0.00033 20.6 0.1 0.00065 19.7 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.1 EWM29196.1 - 0.0057 15.6 0.0 0.011 14.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EWM29196.1 - 0.011 15.5 0.0 0.1 12.3 0.0 2.4 3 0 0 3 3 3 0 Phosphotransferase enzyme family PH PF00169.24 EWM29196.1 - 0.012 15.8 0.4 0.036 14.2 0.2 1.9 1 1 0 1 1 1 0 PH domain Kdo PF06293.9 EWM29196.1 - 0.017 14.1 0.0 0.034 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Rotamase_2 PF13145.1 EWM29196.1 - 0.03 14.9 0.0 0.31 11.6 0.0 2.3 2 0 0 2 2 2 0 PPIC-type PPIASE domain PH_11 PF15413.1 EWM29196.1 - 0.041 14.1 1.0 1.9 8.7 0.7 2.4 1 1 0 1 1 1 0 Pleckstrin homology domain Pox_ser-thr_kin PF05445.6 EWM29196.1 - 0.064 12.0 0.2 0.12 11.1 0.1 1.4 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase CbiX PF01903.12 EWM29197.1 - 8.1e-25 86.9 0.0 1.6e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 CbiX Amidohydro_2 PF04909.9 EWM29197.1 - 0.065 12.7 0.0 0.09 12.3 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase Antimicrobial12 PF08107.6 EWM29197.1 - 0.076 12.5 0.8 0.14 11.6 0.5 1.4 1 0 0 1 1 1 0 Pleurocidin family CbiK PF06180.6 EWM29197.1 - 0.1 11.6 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) MMR_HSR1 PF01926.18 EWM29198.1 - 2.7e-10 40.2 0.1 5.2e-10 39.2 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EWM29198.1 - 0.00014 21.3 0.1 0.31 10.4 0.0 2.4 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Miro PF08477.8 EWM29198.1 - 0.015 15.8 0.0 0.038 14.4 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 EWM29198.1 - 0.027 14.3 4.4 0.61 9.8 0.0 3.4 3 0 0 3 3 3 0 Dynamin family DUF258 PF03193.11 EWM29198.1 - 0.083 12.0 0.1 0.18 10.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 EWM29198.1 - 0.17 11.4 0.0 3.2 7.2 0.0 2.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein FeoB_N PF02421.13 EWM29198.1 - 0.21 10.8 0.3 0.58 9.4 0.1 1.9 2 1 0 2 2 2 0 Ferrous iron transport protein B Spore_IV_A PF09547.5 EWM29198.1 - 0.23 10.1 0.0 0.35 9.5 0.0 1.1 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) DUF605 PF04652.11 EWM29198.1 - 0.31 10.3 1.1 0.69 9.2 0.8 1.5 1 0 0 1 1 1 0 Vta1 like Pkinase PF00069.20 EWM29199.1 - 2.7e-60 203.7 0.0 3.2e-60 203.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM29199.1 - 9.4e-47 159.2 0.0 1.4e-46 158.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EWM29199.1 - 0.00015 20.8 0.0 0.00024 20.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EWM29199.1 - 0.099 11.7 0.1 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1480 PF07351.8 EWM29199.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1480) Abhydrolase_6 PF12697.2 EWM29200.1 - 2e-05 24.5 3.8 0.00028 20.8 2.3 3.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM29200.1 - 0.0014 18.3 0.1 0.0035 17.1 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EWM29201.1 - 7e-12 45.7 0.6 7e-12 45.7 0.4 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM29201.1 - 2.6e-05 24.0 0.4 5.1e-05 23.0 0.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EWM29201.1 - 0.0012 18.4 0.0 0.0024 17.4 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_8 PF06259.7 EWM29201.1 - 0.079 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Orn_Arg_deC_N PF02784.11 EWM29202.1 - 5.6e-29 101.0 0.0 8.2e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EWM29202.1 - 1e-15 57.4 0.0 1.6e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain PAP2_C PF14360.1 EWM29203.1 - 5.1e-16 58.7 2.1 1.2e-15 57.5 1.5 1.7 1 0 0 1 1 1 1 PAP2 superfamily C-terminal PAP2 PF01569.16 EWM29203.1 - 9.4e-08 31.7 1.4 9.4e-08 31.7 1.0 2.1 3 0 0 3 3 3 1 PAP2 superfamily PAP2_3 PF14378.1 EWM29203.1 - 0.00063 19.3 7.4 0.002 17.6 5.1 1.9 1 1 0 1 1 1 1 PAP2 superfamily Mito_carr PF00153.22 EWM29204.1 - 6.1e-63 208.5 3.5 5e-18 64.5 0.0 4.5 4 1 0 4 4 4 4 Mitochondrial carrier protein HIT PF01230.18 EWM29205.1 - 1.6e-28 99.0 0.0 3.6e-28 97.9 0.0 1.6 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EWM29205.1 - 5.3e-24 84.6 0.1 1e-23 83.7 0.0 1.5 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EWM29206.1 - 8.8e-29 99.9 0.0 1.9e-28 98.8 0.0 1.6 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 EWM29206.1 - 7.1e-24 84.2 0.0 1.6e-23 83.1 0.0 1.5 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding K_channel_TID PF07941.6 EWM29207.1 - 0.0086 16.2 10.6 0.017 15.3 7.3 1.5 1 0 0 1 1 1 1 Potassium channel Kv1.4 tandem inactivation domain G0-G1_switch_2 PF15103.1 EWM29207.1 - 0.015 15.5 0.1 0.025 14.7 0.1 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 EphA2_TM PF14575.1 EWM29207.1 - 0.06 13.7 0.2 1.2 9.5 0.0 2.2 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain PRP3 PF08572.5 EWM29207.1 - 0.13 11.6 0.8 0.21 10.9 0.5 1.3 1 0 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) Adeno_E1B_55K_N PF04623.7 EWM29207.1 - 1.2 9.6 7.9 25 5.4 0.0 2.3 2 0 0 2 2 2 0 Adenovirus E1B protein N-terminus Peptidase_C97 PF05903.9 EWM29208.1 - 2e-19 69.8 0.0 2.7e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain Peptidase_C97 PF05903.9 EWM29209.1 - 1.2e-26 93.2 0.0 1.6e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain PIP5K PF01504.13 EWM29210.1 - 1e-50 172.2 0.0 1.9e-50 171.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DEAD PF00270.24 EWM29212.1 - 2.8e-50 170.1 0.0 4.8e-50 169.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EWM29212.1 - 2.1e-26 91.5 0.0 4.1e-26 90.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EWM29212.1 - 0.007 16.2 0.1 0.047 13.5 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AcylCoA_DH_N PF12418.3 EWM29212.1 - 0.015 14.9 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase N terminal AAA_22 PF13401.1 EWM29212.1 - 0.1 12.7 0.1 0.36 10.9 0.1 2.0 1 1 0 1 1 1 0 AAA domain NDK PF00334.14 EWM29213.1 - 1.3e-43 148.0 0.0 1.4e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.13 EWM29213.1 - 0.049 13.3 0.0 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ Kinesin PF00225.18 EWM29216.1 - 9.1e-99 330.3 0.3 5.1e-98 327.8 0.0 2.4 3 0 0 3 3 3 1 Kinesin motor domain Syntaxin-6_N PF09177.6 EWM29217.1 - 4.4e-18 65.4 0.8 6.5e-18 64.9 0.6 1.3 1 0 0 1 1 1 1 Syntaxin 6, N-terminal Mnd1 PF03962.10 EWM29217.1 - 0.0048 16.5 1.4 0.0066 16.1 1.0 1.1 1 0 0 1 1 1 1 Mnd1 family PBC PF03792.8 EWM29217.1 - 0.044 13.4 0.8 0.063 12.9 0.5 1.2 1 0 0 1 1 1 0 PBC domain Acyltransferase PF01553.16 EWM29218.1 - 3.8e-28 97.5 0.0 7e-28 96.7 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DUF374 PF04028.8 EWM29218.1 - 0.097 11.9 0.0 0.22 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF374) CHCH PF06747.8 EWM29219.1 - 0.15 12.0 1.7 0.21 11.5 0.3 2.0 2 0 0 2 2 2 0 CHCH domain GDA1_CD39 PF01150.12 EWM29220.1 - 1e-80 271.3 0.0 1.4e-80 270.9 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF2809 PF10990.3 EWM29220.1 - 0.052 13.9 0.1 0.11 12.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2809) Mito_fiss_reg PF05308.6 EWM29220.1 - 0.8 9.0 6.2 1.5 8.1 4.3 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Acyl_transf_1 PF00698.16 EWM29221.1 - 6.9e-66 222.7 0.0 1.3e-65 221.8 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EWM29221.1 - 1e-42 145.8 0.1 8.3e-41 139.6 0.0 3.3 3 0 0 3 3 3 1 KR domain ketoacyl-synt PF00109.21 EWM29221.1 - 7.6e-41 140.2 0.0 1.7e-40 139.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short PF00106.20 EWM29221.1 - 5.4e-38 130.5 0.0 5.4e-38 130.5 0.0 4.4 4 1 1 5 5 5 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EWM29221.1 - 1.9e-31 108.9 0.0 6.5e-31 107.1 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.17 EWM29221.1 - 2.5e-26 91.8 0.0 6.9e-26 90.4 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EWM29221.1 - 1.1e-21 76.6 0.1 2.6e-20 72.2 0.0 3.1 3 0 0 3 3 3 1 Zinc-binding dehydrogenase PS-DH PF14765.1 EWM29221.1 - 4.1e-19 68.8 0.0 9.7e-12 44.6 0.0 2.5 2 0 0 2 2 2 2 Polyketide synthase dehydratase Epimerase PF01370.16 EWM29221.1 - 3.2e-14 52.9 0.0 1.3e-06 28.0 0.0 2.6 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family ADH_zinc_N_2 PF13602.1 EWM29221.1 - 1e-11 45.8 0.2 2.5e-10 41.3 0.0 3.5 4 0 0 4 4 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EWM29221.1 - 4e-07 29.7 0.0 1.3e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 EWM29221.1 - 5e-07 29.8 0.1 1.5e-06 28.3 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.10 EWM29221.1 - 1.2e-05 24.3 0.0 0.022 13.6 0.0 2.6 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EWM29221.1 - 5.8e-05 23.1 0.3 3.1 7.7 0.0 4.0 3 0 0 3 3 3 2 NADH(P)-binding Thiolase_N PF00108.18 EWM29221.1 - 0.0012 17.9 0.0 0.003 16.5 0.0 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain PseudoU_synth_2 PF00849.17 EWM29222.1 - 2.5e-28 98.9 0.0 4.3e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase TruB_N PF01509.13 EWM29222.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 TruB family pseudouridylate synthase (N terminal domain) zf-RING_2 PF13639.1 EWM29223.1 - 1.1e-12 47.5 8.6 1.1e-12 47.5 5.9 2.4 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EWM29223.1 - 2.1e-08 34.1 6.9 4.5e-08 33.0 2.4 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EWM29223.1 - 2.5e-08 33.4 15.5 4.7e-07 29.3 4.8 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EWM29223.1 - 3.5e-06 26.9 15.1 2.3e-05 24.3 5.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EWM29223.1 - 5.4e-06 26.0 16.7 2.5e-05 23.8 4.8 2.3 2 0 0 2 2 2 2 zinc-RING finger domain PA PF02225.17 EWM29223.1 - 0.0003 20.4 0.0 0.00068 19.2 0.0 1.6 1 1 0 1 1 1 1 PA domain zf-C3HC4 PF00097.20 EWM29223.1 - 0.00088 18.8 8.5 0.00088 18.8 5.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EWM29223.1 - 0.0016 18.2 2.0 0.0016 18.2 1.4 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.2 EWM29223.1 - 0.0082 15.9 8.2 0.027 14.2 0.4 2.4 2 0 0 2 2 2 1 Double zinc ribbon UPF0547 PF10571.4 EWM29223.1 - 0.014 15.0 7.0 0.33 10.6 0.5 2.8 2 1 0 2 2 2 0 Uncharacterised protein family UPF0547 zinc_ribbon_2 PF13240.1 EWM29223.1 - 0.024 14.0 3.3 0.22 11.0 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 EWM29223.1 - 0.069 12.3 4.0 3.1 7.1 0.6 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.1 EWM29223.1 - 1.2 9.0 6.0 12 5.9 0.2 3.4 2 1 1 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EWM29223.1 - 2.8 8.4 5.7 28 5.3 0.2 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type Prok-RING_1 PF14446.1 EWM29223.1 - 3.3 7.4 16.1 1.7 8.4 0.7 3.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.1 EWM29223.1 - 6.2 6.4 15.6 1.4 8.5 4.6 2.7 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EWM29223.1 - 9.6 6.0 9.3 4.4 7.1 3.1 2.7 2 0 0 2 2 2 0 RING-type zinc-finger ANTH PF07651.11 EWM29224.1 - 1e-05 24.4 0.2 0.00048 18.9 0.1 3.0 2 1 0 2 2 2 1 ANTH domain BTV_NS2 PF04514.7 EWM29224.1 - 2.4 6.9 16.6 5.1 5.8 11.5 1.5 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Atg14 PF10186.4 EWM29225.1 - 0.49 9.2 3.3 0.45 9.4 0.9 1.6 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 S1 PF00575.18 EWM29226.1 - 5.9e-13 48.7 1.4 1.3e-12 47.5 0.9 1.6 1 0 0 1 1 1 1 S1 RNA binding domain zf-CCHC_3 PF13917.1 EWM29226.1 - 7.6e-05 22.3 0.2 0.00071 19.2 0.0 2.6 2 0 0 2 2 2 1 Zinc knuckle THRAP3_BCLAF1 PF15440.1 EWM29226.1 - 0.0038 15.9 7.1 0.0038 15.9 4.9 4.1 2 2 2 4 4 4 1 THRAP3/BCLAF1 family RR_TM4-6 PF06459.7 EWM29226.1 - 0.57 10.0 7.8 0.92 9.3 5.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_polI_A34 PF08208.6 EWM29226.1 - 3 7.4 27.8 6.1 6.4 19.3 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 ETF_alpha PF00766.14 EWM29227.1 - 7.2e-37 124.8 1.6 2.7e-35 119.8 0.1 2.3 2 0 0 2 2 2 2 Electron transfer flavoprotein FAD-binding domain ETF PF01012.16 EWM29227.1 - 6.7e-35 120.2 4.2 1.1e-34 119.5 2.9 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain PA28_beta PF02252.13 EWM29228.1 - 3.9e-17 62.1 0.0 6.3e-13 48.4 0.0 2.3 2 0 0 2 2 2 2 Proteasome activator pa28 beta subunit Methyltransf_23 PF13489.1 EWM29229.1 - 1.1e-16 60.9 0.0 1.5e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM29229.1 - 1.3e-11 44.7 0.0 2.2e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM29229.1 - 3.2e-09 37.3 0.0 5.2e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM29229.1 - 6.6e-09 36.1 0.0 1.3e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM29229.1 - 2e-05 24.5 0.1 3.7e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM29229.1 - 3.7e-05 24.0 0.2 0.0001 22.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EWM29229.1 - 8.1e-05 22.0 0.0 0.00016 21.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EWM29229.1 - 0.0001 21.9 0.0 0.00013 21.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EWM29229.1 - 0.0001 21.4 0.0 0.00018 20.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.15 EWM29229.1 - 0.0004 19.5 0.0 0.0011 18.1 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.1 EWM29229.1 - 0.0093 16.7 0.0 0.02 15.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EWM29229.1 - 0.054 12.4 0.0 0.094 11.6 0.0 1.4 1 1 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_2 PF00891.13 EWM29229.1 - 0.11 11.7 0.0 0.22 10.6 0.0 1.4 1 1 0 1 1 1 0 O-methyltransferase Zn_clus PF00172.13 EWM29230.1 - 0.00015 21.5 9.2 0.00015 21.5 6.4 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ARS2 PF04959.8 EWM29231.1 - 4.1e-07 30.4 0.6 7.8e-07 29.5 0.4 1.4 1 0 0 1 1 1 1 Arsenite-resistance protein 2 DUF4187 PF13821.1 EWM29231.1 - 0.014 14.9 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) zf-C2H2 PF00096.21 EWM29231.1 - 0.038 14.3 0.3 0.083 13.2 0.2 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type ELFV_dehydrog PF00208.16 EWM29232.1 - 3.4e-28 98.8 0.0 5.5e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 EWM29232.1 - 1.3e-24 85.9 0.0 6.9e-21 73.5 0.0 2.9 2 1 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase SHMT PF00464.14 EWM29233.1 - 2.4e-173 576.1 0.0 3e-173 575.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 EWM29233.1 - 0.0031 16.6 0.0 0.0064 15.6 0.0 1.7 2 0 0 2 2 2 1 Beta-eliminating lyase Daxx PF03344.10 EWM29235.1 - 0.012 14.0 22.1 0.012 14.1 15.3 1.2 1 0 0 1 1 1 0 Daxx Family DDHD PF02862.12 EWM29235.1 - 0.28 10.9 10.0 0.3 10.8 6.9 1.2 1 0 0 1 1 1 0 DDHD domain SprA-related PF12118.3 EWM29235.1 - 0.31 10.3 12.4 0.35 10.1 8.6 1.2 1 0 0 1 1 1 0 SprA-related family PPP4R2 PF09184.6 EWM29235.1 - 0.56 9.7 24.8 0.11 12.0 14.9 1.5 2 0 0 2 2 2 0 PPP4R2 TSA PF03249.8 EWM29235.1 - 0.64 8.4 5.5 0.62 8.5 3.8 1.0 1 0 0 1 1 1 0 Type specific antigen Zip PF02535.17 EWM29235.1 - 0.94 8.4 5.2 0.91 8.4 3.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2413 PF10310.4 EWM29235.1 - 1.5 7.5 17.3 1.6 7.4 12.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Prothymosin PF03247.9 EWM29235.1 - 2.5 8.3 38.9 0.66 10.1 24.9 1.7 2 0 0 2 2 2 0 Prothymosin/parathymosin family TFIIA PF03153.8 EWM29235.1 - 2.5 7.9 15.2 2.8 7.7 10.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RNase_H2-Ydr279 PF09468.5 EWM29235.1 - 3.2 6.8 9.6 3.5 6.7 6.7 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) VID27 PF08553.5 EWM29235.1 - 3.4 5.7 21.2 3.8 5.6 14.7 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein SID-1_RNA_chan PF13965.1 EWM29235.1 - 3.8 5.5 4.5 3.7 5.5 3.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 NOA36 PF06524.7 EWM29235.1 - 4.5 6.4 12.9 5.7 6.1 9.0 1.1 1 0 0 1 1 1 0 NOA36 protein Serinc PF03348.10 EWM29235.1 - 4.8 5.7 5.5 4.1 5.9 3.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Glucokinase PF02685.11 EWM29239.1 - 1.3e-65 221.2 0.0 2.7e-65 220.2 0.0 1.5 2 0 0 2 2 2 1 Glucokinase DUF563 PF04577.9 EWM29240.1 - 4.2e-19 69.2 0.0 7.5e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) PRK PF00485.13 EWM29242.1 - 0.0017 17.9 0.0 0.15 11.5 0.0 2.1 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family cobW PF02492.14 EWM29242.1 - 0.032 13.6 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 EWM29242.1 - 0.033 13.9 0.0 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain KAP_NTPase PF07693.9 EWM29242.1 - 0.044 12.7 0.0 0.044 12.7 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain Zeta_toxin PF06414.7 EWM29242.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin MIB_HERC2 PF06701.8 EWM29244.1 - 6.1e-09 35.7 4.8 1.5e-08 34.5 3.3 1.6 1 0 0 1 1 1 1 Mib_herc2 zf-Nse PF11789.3 EWM29244.1 - 1.8e-06 27.3 0.3 4.1e-06 26.2 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EWM29244.1 - 1.3e-05 24.7 0.2 6.4e-05 22.5 0.2 2.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 EWM29244.1 - 0.0013 18.5 1.1 0.0046 16.7 0.8 2.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EWM29244.1 - 0.0075 16.1 1.8 0.022 14.6 1.2 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING U-box PF04564.10 EWM29244.1 - 0.0097 15.8 0.0 0.03 14.2 0.0 1.9 1 0 0 1 1 1 1 U-box domain zf-C3HC4_3 PF13920.1 EWM29244.1 - 0.27 10.9 3.1 0.27 10.9 0.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EWM29244.1 - 0.78 9.4 2.5 1.5 8.5 0.4 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Glycolytic PF00274.14 EWM29245.1 - 1.1e-140 468.0 0.0 1.4e-140 467.6 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I MOSC_N PF03476.11 EWM29247.1 - 1.8e-31 108.3 0.0 3.3e-31 107.4 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Peptidase_M24 PF00557.19 EWM29247.1 - 7.2e-30 104.1 0.2 1.3e-29 103.3 0.1 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 MOSC PF03473.12 EWM29247.1 - 1.4e-25 89.2 0.0 2.8e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 MOSC domain PsbP PF01789.11 EWM29249.1 - 1.1e-20 73.8 0.0 1.7e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 PsbP Beach PF02138.13 EWM29252.1 - 1.6e-104 349.1 0.0 2.3e-104 348.6 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.27 EWM29252.1 - 1.7e-12 46.6 0.4 0.00023 20.9 0.0 3.9 3 1 0 3 3 3 2 WD domain, G-beta repeat PH_BEACH PF14844.1 EWM29252.1 - 6.2e-07 29.2 0.1 1.4e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH SBP_bac_5 PF00496.17 EWM29252.1 - 2.1 7.0 0.0 3.5 6.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle UBA_4 PF14555.1 EWM29254.1 - 2e-09 36.7 0.0 3.4e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain Acetyltransf_13 PF13880.1 EWM29255.1 - 1.2e-22 79.4 0.2 2.4e-22 78.4 0.1 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 EWM29255.1 - 3.8e-14 51.9 0.4 3.8e-14 51.9 0.3 1.7 2 0 0 2 2 2 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.19 EWM29255.1 - 0.00048 20.1 0.1 0.0013 18.7 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EWM29255.1 - 0.057 13.5 0.2 0.14 12.3 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF3877 PF12993.2 EWM29255.1 - 0.061 12.8 0.0 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) Acetyltransf_CG PF14542.1 EWM29255.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase TLC PF03219.9 EWM29257.1 - 2.3e-200 666.2 17.1 2.8e-200 665.9 11.9 1.0 1 0 0 1 1 1 1 TLC ATP/ADP transporter Mito_carr PF00153.22 EWM29258.1 - 1.4e-52 175.3 5.7 4.6e-17 61.5 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF605 PF04652.11 EWM29260.1 - 0.0019 17.7 31.1 0.0019 17.7 21.6 2.1 2 1 0 2 2 2 1 Vta1 like DUF940 PF06082.6 EWM29260.1 - 0.63 8.5 17.3 0.96 7.9 12.0 1.4 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) Med15 PF09606.5 EWM29260.1 - 0.66 8.1 85.3 0.025 12.7 54.9 1.6 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal CDC45 PF02724.9 EWM29260.1 - 2 6.3 27.4 3.7 5.4 19.0 1.5 1 0 0 1 1 1 0 CDC45-like protein ETF_QO PF05187.8 EWM29262.1 - 1.6e-35 121.4 0.0 2.7e-35 120.6 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 EWM29262.1 - 1.2e-07 30.9 0.6 0.0083 15.0 0.2 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EWM29262.1 - 1.3e-07 30.8 1.8 0.00056 18.8 1.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EWM29262.1 - 1.9e-07 30.9 0.0 3.2e-06 27.0 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EWM29262.1 - 1.5e-05 24.1 0.0 0.00016 20.8 0.0 2.1 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EWM29262.1 - 0.00012 20.7 0.3 0.00035 19.1 0.2 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 EWM29262.1 - 0.00022 21.3 0.1 0.00058 19.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EWM29262.1 - 0.00082 18.3 0.1 0.0018 17.2 0.1 1.6 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EWM29262.1 - 0.0014 18.5 0.2 0.0031 17.4 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EWM29262.1 - 0.003 17.3 0.1 0.006 16.3 0.0 1.6 1 1 0 1 1 1 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EWM29262.1 - 0.032 13.1 0.0 0.062 12.1 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.2 EWM29262.1 - 0.057 12.4 0.1 0.097 11.7 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EWM29262.1 - 0.073 12.1 0.0 0.15 11.0 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain HAD_2 PF13419.1 EWM29263.1 - 2.3e-12 47.5 0.1 1.7e-05 25.1 0.0 2.5 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EWM29263.1 - 1.3e-09 38.8 0.0 2.5e-09 37.8 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EWM29263.1 - 3e-06 27.0 0.0 0.042 13.7 0.0 2.5 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase zf-ribbon_3 PF13248.1 EWM29263.1 - 0.00016 20.7 2.0 0.00028 19.9 0.6 2.0 2 0 0 2 2 2 1 zinc-ribbon domain zf-DHHC PF01529.15 EWM29263.1 - 0.00037 19.9 0.4 0.00071 19.0 0.3 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase HAD PF12710.2 EWM29263.1 - 0.001 19.2 0.0 0.0019 18.4 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DZR PF12773.2 EWM29263.1 - 0.0061 16.3 3.3 0.016 15.0 2.3 1.7 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.1 EWM29263.1 - 0.0081 15.6 4.2 0.014 14.8 1.2 2.6 2 1 1 3 3 3 1 zinc-ribbon domain UPF0547 PF10571.4 EWM29263.1 - 0.038 13.7 4.9 0.037 13.7 1.8 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Hydrolase_like PF13242.1 EWM29263.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like CbiA PF01656.18 EWM29264.1 - 4.4e-26 91.4 0.0 5.8e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EWM29264.1 - 4.5e-14 52.6 0.0 6.6e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain MipZ PF09140.6 EWM29264.1 - 3e-09 36.3 0.1 5.7e-09 35.4 0.1 1.5 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 EWM29264.1 - 3.2e-06 26.3 3.8 5.6e-06 25.6 2.3 1.5 2 0 0 2 2 2 1 Anion-transporting ATPase YhjQ PF06564.7 EWM29264.1 - 0.0001 21.7 0.1 0.23 10.7 0.1 2.1 2 0 0 2 2 2 2 YhjQ protein Fer4_NifH PF00142.13 EWM29264.1 - 0.0013 18.0 0.0 0.066 12.3 0.2 2.1 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_24 PF13479.1 EWM29264.1 - 0.0057 16.2 0.0 0.0087 15.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EWM29264.1 - 0.035 13.5 1.0 0.092 12.1 0.7 1.6 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 EWM29264.1 - 0.04 13.3 2.3 0.22 10.9 0.9 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ParA PF10609.4 EWM29264.1 - 0.07 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 ParA/MinD ATPase like AAA_10 PF12846.2 EWM29264.1 - 0.12 11.7 1.2 0.24 10.7 0.7 1.5 1 1 0 1 1 1 0 AAA-like domain Peptidase_C2 PF00648.16 EWM29265.1 - 2.8e-31 108.6 0.0 4.3e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 EWM29265.1 - 1.6e-24 86.2 0.0 3.1e-09 36.6 0.0 4.8 4 1 0 4 4 4 4 Calpain large subunit, domain III MIT PF04212.13 EWM29265.1 - 2.3e-05 24.1 0.6 0.023 14.5 0.0 2.5 2 1 0 2 2 2 2 MIT (microtubule interacting and transport) domain A_deaminase PF00962.17 EWM29266.1 - 4.9e-97 324.7 0.0 8.4e-97 324.0 0.0 1.4 1 0 0 1 1 1 1 Adenosine/AMP deaminase Glyco_transf_15 PF01793.11 EWM29268.1 - 8.2e-95 317.5 0.1 3.4e-55 187.3 0.5 2.3 2 0 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase Methyltransf_22 PF13383.1 EWM29268.1 - 3.6e-33 115.1 0.0 6.8e-33 114.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.7 EWM29268.1 - 1.7e-06 28.1 0.0 5.1e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase FkbM domain DUF4185 PF13810.1 EWM29268.1 - 7.2e-05 21.8 0.0 0.00016 20.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) RhoGAP PF00620.22 EWM29269.1 - 1.5e-25 89.6 0.0 2.3e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain ESSS PF10183.4 EWM29270.1 - 1.7e-12 47.6 0.2 2.5e-12 47.1 0.1 1.3 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Unstab_antitox PF09720.5 EWM29270.1 - 0.0029 17.2 1.3 0.0029 17.2 0.9 1.5 2 0 0 2 2 2 1 Putative addiction module component mit_SMPDase PF14724.1 EWM29271.1 - 0.00014 19.8 3.6 0.079 10.7 2.9 2.7 2 1 0 2 2 2 2 Mitochondrial-associated sphingomyelin phosphodiesterase NYD-SP28_assoc PF14775.1 EWM29272.1 - 4.7e-07 29.4 1.0 4.7e-07 29.4 0.7 3.9 4 0 0 4 4 4 1 Sperm tail C-terminal domain APG6 PF04111.7 EWM29272.1 - 1.7 7.6 39.1 0.073 12.1 8.3 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF3287 PF11690.3 EWM29272.1 - 7.7 6.6 19.8 0.037 14.0 2.3 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF3287) DUF2763 PF10961.3 EWM29273.1 - 1.8e-08 34.6 3.2 2.2e-08 34.3 1.9 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2763) SufE PF02657.10 EWM29274.1 - 4.5e-30 103.8 0.0 7.2e-30 103.1 0.0 1.3 1 0 0 1 1 1 1 Fe-S metabolism associated domain BolA PF01722.13 EWM29274.1 - 1.1e-26 92.5 0.1 2.2e-26 91.6 0.0 1.5 1 0 0 1 1 1 1 BolA-like protein GCFC PF07842.7 EWM29276.1 - 1.2e-17 64.1 0.0 9.5e-15 54.6 0.0 2.5 1 1 1 2 2 2 2 GC-rich sequence DNA-binding factor-like protein GCFC PF07842.7 EWM29277.1 - 5.6e-18 65.2 0.0 3e-15 56.3 0.0 2.5 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein DUF948 PF06103.6 EWM29277.1 - 0.14 12.0 0.1 0.73 9.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) GatB_N PF02934.10 EWM29278.1 - 5.2e-85 284.8 0.0 6.3e-85 284.5 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 EWM29278.1 - 1.5e-38 131.8 0.0 2.2e-38 131.2 0.0 1.3 1 0 0 1 1 1 1 GatB domain Tim17 PF02466.14 EWM29279.1 - 6.6e-31 107.0 3.6 9.9e-31 106.4 2.5 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family NUC173 PF08161.7 EWM29281.1 - 4.6e-29 101.1 0.0 1.6e-27 96.1 0.0 3.0 2 1 0 2 2 2 1 NUC173 domain Adaptin_N PF01602.15 EWM29281.1 - 0.00015 20.2 2.7 0.19 9.9 0.1 3.3 3 0 0 3 3 3 2 Adaptin N terminal region Cnd3 PF12719.2 EWM29281.1 - 0.0036 16.3 8.1 0.11 11.4 0.0 3.4 3 0 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain Cnd1 PF12717.2 EWM29281.1 - 0.037 13.8 0.4 12 5.6 0.1 3.7 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EWM29281.1 - 0.76 10.0 13.9 47 4.4 0.0 6.9 8 0 0 8 8 8 0 HEAT repeat HSP70 PF00012.15 EWM29282.1 - 5.3e-61 206.2 0.0 1.7e-60 204.6 0.0 1.7 2 1 0 2 2 2 1 Hsp70 protein Pkinase PF00069.20 EWM29283.1 - 1.4e-70 237.4 0.0 2.2e-70 236.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM29283.1 - 1.3e-40 139.1 0.0 2.1e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.1 EWM29283.1 - 7.7e-14 51.5 0.4 1.4e-08 34.7 0.1 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EWM29283.1 - 4.6e-12 44.3 1.1 7e-06 24.9 0.1 4.0 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 EWM29283.1 - 1.3e-10 40.7 0.5 8.2e-07 28.5 0.0 3.3 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 EWM29283.1 - 2.8e-09 36.0 0.2 0.12 12.3 0.0 3.8 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.1 EWM29283.1 - 2.7e-05 23.3 0.3 0.13 11.6 0.0 2.8 2 0 0 2 2 2 2 EF hand Kinase-like PF14531.1 EWM29283.1 - 0.00033 19.6 0.1 0.4 9.5 0.0 2.6 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.9 EWM29283.1 - 0.0014 17.7 0.7 0.0034 16.4 0.4 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EWM29283.1 - 0.0034 17.1 0.1 0.007 16.1 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EWM29283.1 - 0.0049 16.2 0.0 0.019 14.3 0.0 1.9 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL SPARC_Ca_bdg PF10591.4 EWM29283.1 - 0.014 15.4 1.6 0.019 14.9 0.1 2.0 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF1880 PF08976.6 EWM29283.1 - 0.05 13.7 0.5 0.13 12.3 0.0 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF1880) EF-hand_4 PF12763.2 EWM29283.1 - 0.057 13.1 0.2 0.14 11.9 0.2 1.6 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand E1-E2_ATPase PF00122.15 EWM29284.1 - 0.0017 17.4 0.4 0.099 11.6 0.0 2.4 2 0 0 2 2 2 2 E1-E2 ATPase Synaptobrevin PF00957.16 EWM29285.1 - 6.8e-15 54.4 0.2 1.1e-14 53.8 0.2 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EWM29285.1 - 4.1e-13 48.6 0.0 6.7e-13 47.9 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Nsp1_C PF05064.8 EWM29285.1 - 0.044 13.4 0.3 0.13 11.8 0.1 1.9 1 1 0 2 2 2 0 Nsp1-like C-terminal region MIS13 PF08202.6 EWM29285.1 - 0.045 12.8 0.4 0.064 12.3 0.2 1.1 1 0 0 1 1 1 0 Mis12-Mtw1 protein family DUF1084 PF06454.6 EWM29286.1 - 2.5e-10 39.8 6.4 7.5e-10 38.2 4.5 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) UMPH-1 PF05822.7 EWM29287.1 - 4.1e-26 91.8 0.0 5.6e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) DUF2854 PF11016.3 EWM29288.1 - 6.8e-32 110.0 0.0 1.1e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2854) DUF2854 PF11016.3 EWM29289.1 - 1.2e-08 34.6 0.0 2.1e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2854) DUF914 PF06027.7 EWM29290.1 - 2.6e-07 29.8 1.5 8.8e-06 24.7 1.0 2.1 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 EWM29290.1 - 0.00029 20.9 8.0 0.00029 20.9 5.5 3.1 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EWM29290.1 - 0.0011 18.9 7.7 0.0011 18.9 5.3 3.3 3 0 0 3 3 3 1 EamA-like transporter family TPT PF03151.11 EWM29290.1 - 0.0022 17.6 16.0 0.021 14.4 1.7 3.3 2 2 0 2 2 2 2 Triose-phosphate Transporter family CRT-like PF08627.5 EWM29290.1 - 0.015 15.2 0.6 0.015 15.2 0.4 1.7 2 0 0 2 2 2 0 CRT-like UAA PF08449.6 EWM29290.1 - 0.79 8.5 8.3 0.15 10.9 1.6 2.3 1 1 0 2 2 2 0 UAA transporter family Acetyltransf_1 PF00583.19 EWM29291.1 - 2.2e-29 101.3 0.2 2e-15 56.5 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EWM29291.1 - 3.2e-17 62.7 0.0 6.3e-09 35.9 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EWM29291.1 - 8e-15 54.7 0.1 1e-06 28.7 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 EWM29291.1 - 8.3e-15 54.3 0.0 3.6e-06 26.6 0.0 2.3 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_9 PF13527.1 EWM29291.1 - 2.7e-13 49.9 0.0 1e-06 28.5 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EWM29291.1 - 5e-12 45.9 0.0 2.8e-08 33.7 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EWM29291.1 - 1.7e-10 41.2 0.0 0.00084 19.5 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EWM29291.1 - 1.3e-07 31.6 0.0 0.00057 19.8 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain PPE PF00823.14 EWM29291.1 - 0.094 12.5 2.5 0.16 11.7 1.7 1.2 1 0 0 1 1 1 0 PPE family Acetyltransf_CG PF14542.1 EWM29291.1 - 0.11 12.4 0.0 20 5.1 0.0 2.4 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase FAD_binding_1 PF00667.15 EWM29292.1 - 7.6e-56 188.9 0.0 1.2e-55 188.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EWM29292.1 - 2.3e-34 118.4 0.4 4e-34 117.6 0.2 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EWM29292.1 - 8.3e-17 61.7 0.0 2e-16 60.5 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.15 EWM29293.1 - 5.8e-56 189.3 0.0 9.1e-56 188.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EWM29293.1 - 2.6e-25 89.0 0.1 5.1e-25 88.1 0.1 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EWM29293.1 - 7.6e-17 61.8 0.0 1.7e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain MMgT PF10270.4 EWM29294.1 - 0.001 19.4 0.0 0.0022 18.3 0.0 1.6 1 1 0 1 1 1 1 Membrane magnesium transporter zf-C3HC4_3 PF13920.1 EWM29295.1 - 3.2e-09 36.3 8.5 5.4e-09 35.5 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SH3_3 PF08239.6 EWM29295.1 - 2.9e-05 24.1 0.3 0.0093 16.1 0.1 2.6 2 1 0 2 2 2 2 Bacterial SH3 domain zf-C3HC4_2 PF13923.1 EWM29295.1 - 0.0027 17.7 10.4 0.005 16.8 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EWM29295.1 - 0.062 13.0 9.3 0.12 12.0 6.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 EWM29295.1 - 0.46 10.3 11.3 0.82 9.5 7.8 1.4 1 0 0 1 1 1 0 Ring finger domain zf-P11 PF03854.9 EWM29295.1 - 0.64 9.5 4.5 1.4 8.4 3.1 1.6 1 0 0 1 1 1 0 P-11 zinc finger TRM13 PF05206.9 EWM29297.1 - 6.8e-54 182.8 0.0 3.9e-53 180.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.3 EWM29297.1 - 3e-08 32.8 1.4 6.5e-08 31.8 1.0 1.6 1 0 0 1 1 1 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.7 EWM29297.1 - 6.4e-08 32.1 1.8 6.7e-08 32.0 0.2 1.8 2 0 0 2 2 2 1 U11-48K-like CHHC zinc finger MTS PF05175.9 EWM29297.1 - 0.031 13.6 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.13 EWM29297.1 - 0.093 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase SpoU_methylase PF00588.14 EWM29298.1 - 9.2e-22 77.4 0.0 1.9e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 SpoU rRNA Methylase family Proteasome PF00227.21 EWM29299.1 - 1.6e-27 95.9 0.0 2.3e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Phyto_Pns9_10 PF05878.6 EWM29299.1 - 0.027 13.4 0.1 0.039 12.9 0.1 1.1 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 EF-hand_5 PF13202.1 EWM29300.1 - 2.8e-10 39.0 1.0 0.00024 20.2 0.4 2.5 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.27 EWM29300.1 - 2.6e-09 35.6 0.4 0.00016 20.6 0.3 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EWM29300.1 - 3.1e-08 33.6 0.0 5.5e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EWM29300.1 - 2e-07 30.3 0.4 0.028 14.2 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EWM29300.1 - 2.9e-06 26.8 0.4 0.045 13.3 0.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair GspL_C PF12693.2 EWM29300.1 - 0.0034 17.1 0.5 0.0034 17.1 0.3 2.5 3 0 0 3 3 3 1 GspL periplasmic domain tRNA_synt_2f PF02092.12 EWM29300.1 - 0.03 12.8 0.1 0.041 12.4 0.1 1.1 1 0 0 1 1 1 0 Glycyl-tRNA synthetase beta subunit EMP24_GP25L PF01105.19 EWM29303.1 - 3.7e-30 104.9 0.0 5.7e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD TFIIB PF00382.14 EWM29304.1 - 1.2e-10 41.0 0.0 1.7e-05 24.4 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EWM29304.1 - 0.00014 21.1 1.3 0.00034 19.8 0.1 2.1 2 0 0 2 2 2 1 TFIIB zinc-binding Arteri_Gl PF00951.13 EWM29305.1 - 0.01 15.4 0.0 0.013 15.0 0.0 1.1 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein RF-1 PF00472.15 EWM29306.1 - 1.1e-36 125.1 0.3 2e-36 124.2 0.2 1.5 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 EWM29306.1 - 1.2e-36 124.9 0.1 2.6e-36 123.8 0.1 1.6 1 0 0 1 1 1 1 PCRF domain KH_1 PF00013.24 EWM29308.1 - 1.9e-59 197.1 14.1 6.8e-17 60.8 0.5 4.5 5 0 0 5 5 5 4 KH domain KH_3 PF13014.1 EWM29308.1 - 2e-43 145.3 14.0 8.6e-13 47.6 0.4 4.6 4 0 0 4 4 4 4 KH domain KH_2 PF07650.12 EWM29308.1 - 3.1e-13 49.0 8.6 0.0064 16.0 0.0 4.3 4 0 0 4 4 4 4 KH domain KH_4 PF13083.1 EWM29308.1 - 1.9e-09 37.0 4.3 0.013 15.0 0.1 3.9 4 0 0 4 4 4 3 KH domain KH_5 PF13184.1 EWM29308.1 - 2.7e-09 36.6 0.6 0.28 11.0 0.0 4.2 4 0 0 4 4 4 3 NusA-like KH domain dUTPase PF00692.14 EWM29308.1 - 0.1 12.0 0.5 29 4.1 0.0 3.2 3 0 0 3 3 3 0 dUTPase PAT1 PF09770.4 EWM29308.1 - 2.7 6.1 47.7 3.9 5.6 33.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 EWM29308.1 - 4 7.2 24.2 9.4 6.0 16.8 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ABC1 PF03109.11 EWM29309.1 - 1.3e-18 67.1 0.0 3.9e-18 65.5 0.0 1.8 2 0 0 2 2 2 1 ABC1 family RIO1 PF01163.17 EWM29309.1 - 0.01 15.1 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.20 EWM29309.1 - 0.025 13.7 0.0 0.14 11.2 0.0 2.2 1 1 0 1 1 1 0 Protein kinase domain APH PF01636.18 EWM29309.1 - 0.056 13.1 4.8 0.35 10.5 3.4 2.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family zf-RING_2 PF13639.1 EWM29312.1 - 1.8e-12 46.8 12.5 1.8e-12 46.8 8.7 3.1 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 EWM29312.1 - 2.8e-05 24.0 12.6 2.8e-05 24.0 8.8 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EWM29312.1 - 0.0024 17.9 9.9 0.0024 17.9 6.9 2.6 3 1 0 3 3 3 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EWM29312.1 - 0.0028 17.3 10.5 0.0028 17.3 7.3 3.5 3 1 0 3 3 3 1 zinc-RING finger domain BRCA-2_OB1 PF09103.5 EWM29313.1 - 7.7e-29 99.7 0.0 1.4e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.5 EWM29313.1 - 1.9e-11 43.8 0.0 1.1e-10 41.3 0.0 2.1 1 1 0 1 1 1 1 BRCA2, helical Mpp10 PF04006.7 EWM29314.1 - 1.7e-72 244.6 23.3 2e-72 244.4 16.1 1.1 1 0 0 1 1 1 1 Mpp10 protein ubiquitin PF00240.18 EWM29315.1 - 4.5e-05 22.7 0.0 8.2e-05 21.9 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EWM29315.1 - 0.076 12.7 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ist1 PF03398.9 EWM29316.1 - 5.2e-58 195.0 5.8 6.4e-58 194.7 4.0 1.0 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Ribosomal_L29e PF01779.12 EWM29317.1 - 2.1e-20 72.2 8.8 4e-20 71.3 6.1 1.5 1 0 0 1 1 1 1 Ribosomal L29e protein family GNT-I PF03071.10 EWM29317.1 - 0.023 13.2 0.1 0.025 13.1 0.1 1.1 1 0 0 1 1 1 0 GNT-I family NAD_binding_10 PF13460.1 EWM29318.1 - 1.5e-20 74.0 1.0 9.6e-14 51.7 0.2 2.3 2 0 0 2 2 2 2 NADH(P)-binding NmrA PF05368.8 EWM29318.1 - 4.6e-13 48.9 0.2 7.9e-13 48.2 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EWM29318.1 - 3.3e-08 33.2 0.3 4.4e-07 29.5 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EWM29318.1 - 4.9e-07 28.7 0.1 6.8e-07 28.2 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EWM29318.1 - 2.3e-05 24.4 1.6 4.2e-05 23.5 0.3 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EWM29318.1 - 0.0015 18.1 0.3 0.0039 16.8 0.2 1.8 1 0 0 1 1 1 1 KR domain CIA30 PF08547.7 EWM29318.1 - 0.013 15.3 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) TrkA_N PF02254.13 EWM29318.1 - 0.041 13.8 0.1 0.085 12.8 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain DUF1510 PF07423.6 EWM29319.1 - 0.0062 15.9 6.2 0.0062 15.9 4.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) Ycf1 PF05758.7 EWM29319.1 - 0.18 9.5 8.1 0.52 7.9 5.6 1.6 1 1 0 1 1 1 0 Ycf1 Trm112p PF03966.11 EWM29320.1 - 1.5e-16 60.4 0.0 2.1e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Trm112p-like protein Plectin PF00681.15 EWM29320.1 - 0.0093 15.4 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Plectin repeat Bac_rhamnosid PF05592.6 EWM29321.1 - 8.5e-123 410.2 0.0 1.2e-122 409.7 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 EWM29321.1 - 3.1e-32 111.4 0.1 3e-31 108.2 0.0 2.2 1 1 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain ERCC4 PF02732.10 EWM29322.1 - 4.1e-24 84.9 0.0 6.3e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 EWM29322.1 - 4.7e-05 23.4 0.0 0.00011 22.2 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain SmpB PF01668.13 EWM29323.1 - 5.8e-19 67.6 0.0 8.7e-19 67.1 0.0 1.3 1 0 0 1 1 1 1 SmpB protein TP1 PF02079.11 EWM29323.1 - 0.018 14.8 0.1 0.05 13.3 0.0 1.8 1 0 0 1 1 1 0 Nuclear transition protein 1 PHD_2 PF13831.1 EWM29323.1 - 1.7 8.0 6.5 7.4 5.9 0.2 2.6 2 0 0 2 2 2 0 PHD-finger FKBP_C PF00254.23 EWM29325.1 - 2.9e-14 52.8 0.0 5.5e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Mesd PF10185.4 EWM29326.1 - 2.4e-08 33.8 0.5 3.1e-08 33.4 0.3 1.1 1 0 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor BTB PF00651.26 EWM29327.1 - 5.7e-22 77.7 0.1 1.5e-21 76.4 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.10 EWM29327.1 - 2.2e-06 27.4 0.0 3.1e-05 23.7 0.0 2.4 1 1 0 1 1 1 1 BTB And C-terminal Kelch Proteasom_Rpn13 PF04683.8 EWM29328.1 - 1.1e-23 83.0 0.2 1.7e-23 82.5 0.1 1.2 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Ribosomal_S11 PF00411.14 EWM29329.1 - 7.9e-41 138.6 0.4 9.8e-41 138.3 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 E1_dh PF00676.15 EWM29330.1 - 2.5e-101 338.3 0.2 6.2e-101 337.0 0.0 1.7 2 0 0 2 2 2 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EWM29330.1 - 0.0028 16.6 0.0 0.0069 15.3 0.0 1.6 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase YbaB_DNA_bd PF02575.11 EWM29330.1 - 0.007 16.2 0.1 0.025 14.4 0.0 1.9 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family RVT_1 PF00078.22 EWM29330.1 - 0.2 10.9 0.0 0.39 10.0 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) HSF_DNA-bind PF00447.12 EWM29331.1 - 2.8e-28 98.1 0.0 4e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding FlaC_arch PF05377.6 EWM29331.1 - 0.0039 17.0 0.3 0.0086 15.9 0.2 1.5 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) AKNA PF12443.3 EWM29331.1 - 0.039 13.9 0.1 0.09 12.8 0.1 1.5 1 0 0 1 1 1 0 AT-hook-containing transcription factor DUF2730 PF10805.3 EWM29331.1 - 0.072 12.8 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DivIC PF04977.10 EWM29331.1 - 0.089 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF4407 PF14362.1 EWM29331.1 - 0.11 11.4 3.6 0.14 11.0 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Nucleoplasmin PF03066.10 EWM29331.1 - 0.15 11.6 1.9 0.27 10.7 1.3 1.4 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 EWM29331.1 - 0.2 11.2 2.4 0.16 11.5 0.8 1.5 2 0 0 2 2 2 0 Sigma-70, non-essential region U79_P34 PF03064.11 EWM29331.1 - 0.33 10.4 7.2 0.52 9.7 5.0 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Myc_N PF01056.13 EWM29331.1 - 1.9 7.5 4.2 3.4 6.7 2.9 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Mpp10 PF04006.7 EWM29332.1 - 3e-15 55.6 6.5 3.5e-15 55.4 4.5 1.0 1 0 0 1 1 1 1 Mpp10 protein DUF2201_N PF13203.1 EWM29332.1 - 0.1 11.7 0.9 0.14 11.3 0.6 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.9 EWM29332.1 - 0.84 7.5 8.3 0.94 7.4 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Paf1 PF03985.8 EWM29332.1 - 1.2 7.8 13.9 1.4 7.5 9.7 1.1 1 0 0 1 1 1 0 Paf1 DUF2457 PF10446.4 EWM29332.1 - 4.4 5.9 17.4 6.1 5.4 12.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) IGPS PF00218.16 EWM29333.1 - 8.1e-15 54.5 0.0 1.3e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase TMP-TENI PF02581.12 EWM29333.1 - 0.011 14.8 0.0 0.03 13.4 0.0 1.7 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI UCH PF00443.24 EWM29334.1 - 4.4e-27 94.8 0.0 6.8e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EWM29334.1 - 3.5e-13 49.4 1.3 6.2e-13 48.6 0.9 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EWM29334.1 - 0.015 14.7 0.0 0.14 11.6 0.0 2.0 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase PD40 PF07676.7 EWM29335.1 - 1.6e-05 24.3 0.1 0.0028 17.2 0.0 3.9 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 EWM29335.1 - 0.0046 15.6 0.0 0.053 12.0 0.0 2.6 2 1 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region RVT_N PF13655.1 EWM29335.1 - 0.18 11.8 0.2 4.7 7.3 0.0 2.4 2 0 0 2 2 2 0 N-terminal domain of reverse transcriptase eIF-3c_N PF05470.7 EWM29336.1 - 5.3 5.0 10.6 7.5 4.5 7.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SIR2 PF02146.12 EWM29337.1 - 1e-40 139.3 0.0 1.4e-40 138.9 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 EWM29337.1 - 0.089 12.5 0.0 1 9.1 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain UDPGT PF00201.13 EWM29338.1 - 7.1e-09 34.7 0.2 6.7e-06 24.9 0.0 2.1 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.15 EWM29338.1 - 0.00018 21.3 0.1 0.0058 16.3 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain GDI PF00996.13 EWM29339.1 - 1.1e-48 165.6 0.0 4.4e-30 104.3 0.0 3.9 2 1 0 2 2 2 2 GDP dissociation inhibitor Abi PF02517.11 EWM29340.1 - 2.8e-17 62.6 4.8 2.8e-17 62.6 3.3 2.1 2 0 0 2 2 2 1 CAAX protease self-immunity CAP_GLY PF01302.20 EWM29341.1 - 2.9e-14 52.5 0.0 7.1e-14 51.2 0.0 1.7 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 EWM29341.1 - 1e-12 47.3 5.9 4.2e-05 23.0 0.1 4.5 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EWM29341.1 - 4.5e-08 32.7 11.1 0.00057 19.5 0.0 4.2 2 2 1 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 EWM29341.1 - 0.00018 21.0 8.6 16 5.9 0.0 6.6 6 1 0 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.1 EWM29341.1 - 0.0028 17.5 8.0 1e+02 3.4 0.0 7.5 8 0 0 8 8 8 0 Leucine Rich repeat LRR_7 PF13504.1 EWM29341.1 - 0.0054 16.7 13.4 65 4.4 0.0 7.3 7 0 0 7 7 7 0 Leucine rich repeat LRR_9 PF14580.1 EWM29341.1 - 0.092 12.2 0.0 0.34 10.4 0.0 1.9 2 0 0 2 2 2 0 Leucine-rich repeat Ubiquitin_2 PF14560.1 EWM29341.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain GFA PF04828.9 EWM29342.1 - 2.2e-08 33.9 1.3 2.2e-08 33.9 0.9 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme TMEM187 PF15100.1 EWM29342.1 - 0.11 11.8 0.2 0.13 11.6 0.1 1.1 1 0 0 1 1 1 0 TMEM187 protein family Ribosomal_L37e PF01907.14 EWM29342.1 - 0.27 11.0 4.1 0.3 10.9 0.3 2.7 2 1 0 2 2 2 0 Ribosomal protein L37e CoA_transf_3 PF02515.12 EWM29343.1 - 2.6e-64 216.0 0.0 4.4e-64 215.2 0.0 1.4 1 0 0 1 1 1 1 CoA-transferase family III TctA PF01970.11 EWM29343.1 - 0.086 11.2 0.0 0.13 10.6 0.0 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family DUF1992 PF09350.5 EWM29344.1 - 1e-14 54.1 0.0 2.6e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) TLC PF03219.9 EWM29345.1 - 1.3e-153 512.0 19.5 1.7e-153 511.6 13.5 1.1 1 0 0 1 1 1 1 TLC ATP/ADP transporter CIA30 PF08547.7 EWM29347.1 - 5.7e-34 117.2 0.0 8.5e-34 116.6 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) NAD_binding_10 PF13460.1 EWM29347.1 - 8.8e-24 84.5 0.0 7.8e-11 42.3 0.0 2.3 2 0 0 2 2 2 2 NADH(P)-binding NmrA PF05368.8 EWM29347.1 - 3.2e-09 36.3 0.0 5.1e-07 29.1 0.0 2.4 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.16 EWM29347.1 - 2.7e-08 33.5 0.0 1.1e-06 28.2 0.0 2.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EWM29347.1 - 1.9e-07 31.1 0.6 4.4e-07 29.9 0.4 1.6 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EWM29347.1 - 4.1e-05 22.6 0.0 0.043 12.7 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein KR PF08659.5 EWM29347.1 - 0.00035 20.2 0.3 0.00061 19.5 0.2 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EWM29347.1 - 0.00037 19.2 0.0 0.00056 18.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EWM29347.1 - 0.0021 16.9 0.0 0.047 12.5 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain CBM_11 PF03425.8 EWM29347.1 - 0.0045 16.6 0.0 0.0071 16.0 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain (family 11) Polysacc_synt_2 PF02719.10 EWM29347.1 - 0.015 14.2 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 EWM29347.1 - 0.15 12.3 0.1 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain AMP-binding PF00501.23 EWM29348.1 - 2.1e-94 316.2 0.2 2.6e-94 316.0 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EWM29348.1 - 5e-21 75.4 0.9 2.3e-20 73.2 0.2 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain KNOX1 PF03790.8 EWM29348.1 - 0.031 13.6 0.8 0.072 12.4 0.1 1.9 2 0 0 2 2 2 0 KNOX1 domain TPR_11 PF13414.1 EWM29349.1 - 1.2e-05 24.8 0.1 2.3e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 EWM29349.1 - 0.00019 20.8 0.2 0.00052 19.4 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EWM29349.1 - 0.0029 17.3 0.5 0.01 15.6 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat 2Fe-2S_thioredx PF01257.14 EWM29349.1 - 0.0064 16.0 0.1 0.039 13.5 0.1 2.2 1 1 1 2 2 2 1 Thioredoxin-like [2Fe-2S] ferredoxin TPR_7 PF13176.1 EWM29349.1 - 0.037 13.8 0.0 0.092 12.5 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 EWM29349.1 - 0.1 12.4 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 EWM29349.1 - 0.15 11.9 0.2 0.25 11.2 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TTL PF03133.10 EWM29350.1 - 1.1e-21 77.0 0.0 3.6e-11 42.5 0.0 3.1 3 0 0 3 3 3 3 Tubulin-tyrosine ligase family Zn_clus PF00172.13 EWM29352.1 - 7.2e-08 32.2 10.9 1.2e-07 31.4 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CRS1_YhbY PF01985.16 EWM29353.1 - 3.5e-09 36.5 0.9 6.4e-09 35.6 0.6 1.5 1 1 0 1 1 1 1 CRS1 / YhbY (CRM) domain Redoxin PF08534.5 EWM29355.1 - 6.8e-23 80.8 0.0 8.4e-23 80.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EWM29355.1 - 1.2e-07 31.4 0.0 1.6e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Aldose_epim PF01263.15 EWM29356.1 - 4.8e-75 252.4 0.0 1.4e-74 250.8 0.0 1.6 1 1 0 1 1 1 1 Aldose 1-epimerase Hydrolase_like PF13242.1 EWM29356.1 - 0.046 13.4 0.0 0.091 12.4 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like Bromodomain PF00439.20 EWM29357.1 - 2e-19 69.3 0.0 3.4e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Bromodomain Ofd1_CTDD PF10637.4 EWM29358.1 - 1.1e-65 221.4 0.0 4.3e-60 203.0 0.0 2.3 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 EWM29358.1 - 4e-17 62.5 0.0 6.7e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PDZ PF00595.19 EWM29359.1 - 1.4e-05 25.1 0.0 3.2e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EWM29359.1 - 0.00084 19.1 0.0 0.0029 17.4 0.0 1.9 1 0 0 1 1 1 1 PDZ domain XPA_C PF05181.7 EWM29360.1 - 3.8e-09 35.9 0.1 7.9e-09 34.9 0.1 1.5 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.13 EWM29360.1 - 0.0039 16.8 0.2 0.0059 16.2 0.1 1.3 1 0 0 1 1 1 1 XPA protein N-terminal DUF2762 PF10960.3 EWM29360.1 - 0.43 10.3 5.9 0.93 9.2 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2762) FANCI_S1-cap PF14674.1 EWM29360.1 - 1.3 9.1 4.7 0.83 9.7 1.4 1.9 1 1 1 2 2 2 0 FANCI solenoid 1 cap Abhydrolase_5 PF12695.2 EWM29361.1 - 8.4e-15 54.7 0.2 1.3e-14 54.1 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EWM29361.1 - 1.5e-08 34.7 3.1 0.0003 20.7 0.7 2.6 2 1 1 3 3 3 2 Alpha/beta hydrolase family DLH PF01738.13 EWM29361.1 - 0.0021 17.3 0.0 0.0033 16.7 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 EWM29361.1 - 0.0063 16.0 0.0 0.11 11.9 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold WD40 PF00400.27 EWM29362.1 - 9.6e-53 174.2 19.3 2.4e-08 33.5 0.3 9.0 9 0 0 9 9 9 8 WD domain, G-beta repeat DENN PF02141.16 EWM29362.1 - 4.3e-15 55.9 0.4 8.7e-15 54.9 0.3 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 EWM29362.1 - 1.4e-12 47.4 0.1 5.9e-12 45.4 0.1 2.0 2 0 0 2 2 2 1 dDENN domain Nup160 PF11715.3 EWM29362.1 - 0.0084 14.2 8.0 0.015 13.4 0.6 3.7 2 1 3 5 5 5 1 Nucleoporin Nup120/160 RCC1 PF00415.13 EWM29363.1 - 1.9e-60 200.8 8.5 1.4e-10 41.2 0.3 7.9 7 2 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EWM29363.1 - 9.1e-27 92.0 38.4 2.2e-05 23.9 0.5 7.4 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat DUF4213 PF13938.1 EWM29363.1 - 0.0094 16.0 1.4 20 5.3 0.0 4.4 4 1 1 5 5 5 1 Domain of unknown function (DUF4213) SIC PF03482.8 EWM29364.1 - 0.038 13.6 0.0 0.044 13.3 0.0 1.1 1 0 0 1 1 1 0 sic protein LSM PF01423.17 EWM29365.1 - 3.6e-13 48.8 0.2 5.2e-13 48.3 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EWM29365.1 - 0.0011 18.8 0.1 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain DKCLD PF08068.7 EWM29366.1 - 2e-30 104.4 0.4 2.3e-29 101.0 0.1 2.6 3 0 0 3 3 3 1 DKCLD (NUC011) domain TruB_N PF01509.13 EWM29366.1 - 2.4e-22 79.7 0.5 2.4e-19 69.9 0.4 3.3 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EWM29366.1 - 4e-21 74.5 3.1 1.2e-20 73.0 2.2 1.9 1 0 0 1 1 1 1 PUA domain TFIIA PF03153.8 EWM29367.1 - 0.18 11.6 2.9 0.2 11.5 2.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit His_Phos_1 PF00300.17 EWM29368.1 - 2.9e-18 66.4 0.6 4e-18 66.0 0.0 1.5 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) DAO PF01266.19 EWM29369.1 - 9.1e-62 209.0 2.9 1.2e-61 208.6 2.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EWM29369.1 - 2.7e-11 42.9 3.7 1.2e-10 40.8 2.6 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EWM29369.1 - 1.1e-08 35.1 0.0 1.1e-06 28.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EWM29369.1 - 2e-07 30.3 0.8 3.2e-07 29.7 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EWM29369.1 - 6.9e-06 25.1 0.2 0.00014 20.8 0.5 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EWM29369.1 - 0.00016 21.6 0.6 0.00034 20.5 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EWM29369.1 - 0.00019 20.0 0.8 0.0038 15.7 0.9 2.0 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EWM29369.1 - 0.00019 20.6 0.7 0.00035 19.7 0.5 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_7 PF13241.1 EWM29369.1 - 0.0002 21.5 0.0 0.00041 20.5 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding FAD_oxidored PF12831.2 EWM29369.1 - 0.00021 20.5 0.9 0.00038 19.6 0.6 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EWM29369.1 - 0.00033 19.6 0.7 0.0031 16.4 0.3 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 EWM29369.1 - 0.00045 20.5 0.4 0.00096 19.5 0.3 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EWM29369.1 - 0.0043 17.1 0.0 0.018 15.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.1 EWM29369.1 - 0.0068 16.4 0.7 0.017 15.1 0.5 1.7 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 EWM29369.1 - 0.014 15.4 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Trp_halogenase PF04820.9 EWM29369.1 - 0.015 13.9 0.6 3.2 6.2 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase UDPG_MGDP_dh_N PF03721.9 EWM29369.1 - 0.024 14.0 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_9 PF13454.1 EWM29369.1 - 0.027 14.2 0.4 2.1 8.1 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EWM29369.1 - 0.031 14.3 0.1 0.054 13.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EWM29369.1 - 0.086 12.4 0.2 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAGAT PF03982.8 EWM29372.1 - 4.6e-35 120.7 0.0 7e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase FKBP_C PF00254.23 EWM29373.1 - 2.2e-35 120.5 0.0 3.3e-35 119.9 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pneumo_att_G PF05539.6 EWM29374.1 - 0.5 9.6 2.4 0.8 9.0 1.7 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Mpv17_PMP22 PF04117.7 EWM29375.1 - 1.8e-12 46.6 0.7 5.5e-12 45.1 0.0 2.1 2 0 0 2 2 2 1 Mpv17 / PMP22 family Acyl_transf_1 PF00698.16 EWM29376.1 - 5.3e-65 219.8 0.0 9.9e-65 218.9 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EWM29376.1 - 7.4e-44 149.5 0.5 1.1e-41 142.5 0.0 3.4 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 EWM29376.1 - 5.3e-40 137.0 5.3 1.2e-38 132.6 0.0 4.1 3 1 1 4 4 4 1 short chain dehydrogenase ketoacyl-synt PF00109.21 EWM29376.1 - 6.3e-40 137.2 0.0 1.5e-39 135.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain NAD_binding_4 PF07993.7 EWM29376.1 - 1.2e-32 112.7 0.0 5.6e-32 110.6 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.17 EWM29376.1 - 1.9e-26 92.2 0.0 6.9e-26 90.4 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EWM29376.1 - 2e-21 75.9 0.1 1.3e-20 73.2 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PS-DH PF14765.1 EWM29376.1 - 1.3e-18 67.2 0.0 3.3e-16 59.3 0.0 2.7 1 1 0 1 1 1 1 Polyketide synthase dehydratase Epimerase PF01370.16 EWM29376.1 - 1.1e-14 54.5 0.0 1.1e-06 28.3 0.0 2.8 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family ADH_zinc_N_2 PF13602.1 EWM29376.1 - 2.8e-11 44.3 0.0 4.7e-10 40.4 0.0 3.2 3 0 0 3 3 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EWM29376.1 - 3.2e-08 33.3 0.0 1.2e-07 31.4 0.0 2.0 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 EWM29376.1 - 1.3e-06 28.5 0.1 3.8e-06 27.0 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.10 EWM29376.1 - 0.0004 19.3 0.0 0.022 13.6 0.0 2.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Thiolase_N PF00108.18 EWM29376.1 - 0.0014 17.7 0.0 0.0032 16.4 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain RRP7 PF12923.2 EWM29376.1 - 0.85 9.6 4.9 0.48 10.4 1.6 2.0 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) PQ-loop PF04193.9 EWM29377.1 - 5.1e-27 93.2 7.1 3.1e-13 49.0 1.0 3.2 2 0 0 2 2 2 2 PQ loop repeat Kua-UEV1_localn PF10520.4 EWM29378.1 - 6.4e-51 172.5 0.7 9.9e-51 171.9 0.5 1.3 1 0 0 1 1 1 1 Kua-ubiquitin conjugating enzyme hybrid localisation domain FA_hydroxylase PF04116.8 EWM29378.1 - 0.25 11.7 4.7 0.83 10.0 3.3 1.9 1 1 0 1 1 1 0 Fatty acid hydroxylase superfamily WD40 PF00400.27 EWM29379.1 - 1.8e-29 100.4 9.9 3.8e-07 29.7 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat IKI3 PF04762.7 EWM29379.1 - 0.15 9.8 0.0 0.23 9.2 0.0 1.2 1 0 0 1 1 1 0 IKI3 family tRNA-synt_1g PF09334.6 EWM29380.1 - 5.2e-109 364.4 0.3 2e-107 359.2 0.2 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EWM29380.1 - 2.3e-35 121.6 0.5 2e-19 69.0 0.0 3.7 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA_bind PF01588.15 EWM29380.1 - 2.2e-28 97.9 0.1 4.4e-28 96.9 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain tRNA-synt_1e PF01406.14 EWM29380.1 - 6.9e-12 45.0 0.0 2.1e-05 23.8 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 EWM29380.1 - 4.4e-07 28.9 0.0 0.00092 17.9 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (K) Anticodon_1 PF08264.8 EWM29380.1 - 0.0024 17.6 0.0 0.0051 16.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Mannosyl_trans3 PF11051.3 EWM29381.1 - 8e-25 87.7 0.0 2e-24 86.4 0.0 1.5 1 1 0 1 1 1 1 Mannosyltransferase putative Mpv17_PMP22 PF04117.7 EWM29382.1 - 2e-22 78.6 2.6 2e-22 78.6 1.8 1.6 1 1 0 1 1 1 1 Mpv17 / PMP22 family Solute_trans_a PF03619.11 EWM29383.1 - 1.7e-85 286.6 13.6 2.3e-85 286.2 9.4 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha SRP54 PF00448.17 EWM29383.1 - 4.6e-66 222.0 0.0 1.1e-65 220.7 0.0 1.7 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 EWM29383.1 - 1.8e-08 34.3 0.9 3.8e-08 33.3 0.6 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_16 PF13191.1 EWM29383.1 - 3.5e-06 27.1 0.2 4.4e-05 23.5 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EWM29383.1 - 3.8e-05 23.3 0.1 0.00012 21.7 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EWM29383.1 - 7.8e-05 22.8 0.0 0.00023 21.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EWM29383.1 - 0.0026 17.3 1.5 0.0049 16.4 0.1 2.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EWM29383.1 - 0.0064 15.6 0.0 0.0064 15.6 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_24 PF13479.1 EWM29383.1 - 0.0086 15.6 0.2 0.031 13.8 0.0 1.9 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 EWM29383.1 - 0.012 15.2 0.0 0.036 13.7 0.0 1.8 1 0 0 1 1 1 0 NACHT domain MobB PF03205.9 EWM29383.1 - 0.016 14.8 0.0 0.04 13.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 EWM29383.1 - 0.035 13.8 0.0 0.089 12.4 0.0 1.6 2 0 0 2 2 2 0 Archaeal ATPase CbiA PF01656.18 EWM29383.1 - 0.054 12.8 0.2 0.16 11.3 0.2 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_14 PF13173.1 EWM29383.1 - 0.089 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EWM29383.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain Phage_Coat_Gp8 PF05371.7 EWM29383.1 - 0.27 10.8 1.3 3.8 7.1 0.1 2.7 2 0 0 2 2 2 0 Phage major coat protein, Gp8 Metallophos PF00149.23 EWM29385.1 - 7.2e-37 126.7 0.1 9.1e-37 126.3 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EWM29385.1 - 0.091 12.5 0.0 0.13 12.0 0.0 1.3 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain MFS_1 PF07690.11 EWM29386.1 - 2.7e-12 46.1 33.0 5.6e-12 45.0 22.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily EIID-AGA PF03613.9 EWM29386.1 - 0.0097 14.8 2.7 0.019 13.8 1.9 1.5 1 0 0 1 1 1 1 PTS system mannose/fructose/sorbose family IID component IFRD PF05004.8 EWM29387.1 - 7.4e-34 117.2 1.0 9.2e-34 116.9 0.7 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) Urb2 PF10441.4 EWM29388.1 - 5.4e-18 65.4 0.0 7.7e-17 61.6 0.0 2.9 2 1 0 2 2 2 1 Urb2/Npa2 family Glyco_hydro_81 PF03639.8 EWM29390.1 - 1.5e-113 380.2 0.0 6.5e-113 378.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 81 Exo_endo_phos PF03372.18 EWM29391.1 - 3.2e-11 43.6 4.3 9.4e-10 38.8 3.0 2.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family 7tm_1 PF00001.16 EWM29391.1 - 0.45 9.6 12.1 0.3 10.1 6.5 1.9 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) Thiolase_N PF00108.18 EWM29392.1 - 5.3e-84 281.3 0.2 1.8e-83 279.5 0.0 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EWM29392.1 - 1.5e-42 143.8 2.6 5.4e-42 142.1 1.6 2.2 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EWM29392.1 - 0.18 11.2 3.6 0.83 9.0 0.8 2.6 2 1 1 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain N2227 PF07942.7 EWM29393.1 - 5.2e-37 127.2 0.0 1.9e-21 76.2 0.0 2.2 2 0 0 2 2 2 2 N2227-like protein Methyltransf_11 PF08241.7 EWM29393.1 - 2.9e-05 24.4 0.0 0.033 14.6 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EWM29393.1 - 0.0047 17.3 0.0 0.54 10.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM29393.1 - 0.0055 17.2 0.0 0.041 14.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM29393.1 - 0.0076 15.8 0.0 0.39 10.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM29393.1 - 0.011 15.4 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_29 PF03141.11 EWM29393.1 - 0.037 12.3 0.0 0.057 11.7 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase C2 PF00168.25 EWM29394.1 - 6.5e-11 41.9 0.0 1.1e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 C2 domain Herpes_gE PF02480.11 EWM29394.1 - 0.12 10.6 1.0 0.15 10.2 0.3 1.4 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E YadA_anchor PF03895.10 EWM29395.1 - 0.31 11.0 3.8 0.16 11.9 1.1 1.6 2 0 0 2 2 2 0 YadA-like C-terminal region Cation_efflux PF01545.16 EWM29396.1 - 1.2e-53 182.1 13.0 4.9e-49 166.9 6.9 2.7 2 1 0 2 2 2 2 Cation efflux family HGTP_anticodon PF03129.15 EWM29397.1 - 2.5e-16 59.3 0.0 4.9e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain ProRS-C_1 PF09180.6 EWM29397.1 - 8.4e-16 57.6 0.0 1.7e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 EWM29397.1 - 2.3e-13 50.1 0.0 3.6e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS PF00458.15 EWM29397.1 - 9.2e-11 41.2 0.0 2.2e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 WHEP-TRS domain CPSase_L_D2 PF02786.12 EWM29398.1 - 1.4e-103 344.6 0.1 2.3e-77 259.0 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 EWM29398.1 - 7.5e-49 164.5 0.0 1.5e-48 163.6 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EWM29398.1 - 3.9e-42 143.8 0.0 8.5e-42 142.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.14 EWM29398.1 - 2.5e-37 127.3 0.0 5.9e-37 126.1 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 EWM29398.1 - 3.8e-34 117.0 0.0 3.8e-18 65.6 0.0 2.7 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EWM29398.1 - 7e-28 97.6 0.3 1.3e-15 57.6 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.17 EWM29398.1 - 5.6e-16 58.2 0.0 1.3e-14 53.9 0.0 3.2 3 0 0 3 3 3 1 MGS-like domain ATPgrasp_Ter PF15632.1 EWM29398.1 - 9.7e-15 54.1 0.0 8.1e-09 34.6 0.0 3.0 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EWM29398.1 - 1.5e-13 50.5 0.1 2.6e-07 30.1 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EWM29398.1 - 3.3e-13 49.4 0.7 1.1e-05 24.9 0.0 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus Peptidase_C26 PF07722.8 EWM29398.1 - 1.1e-05 25.0 0.1 0.00075 19.0 0.1 2.5 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 EWM29398.1 - 0.00013 21.9 0.1 0.7 9.7 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain CoA_binding_2 PF13380.1 EWM29398.1 - 0.019 15.1 0.1 0.28 11.3 0.0 3.0 4 0 0 4 4 3 0 CoA binding domain B12-binding PF02310.14 EWM29398.1 - 0.055 13.3 0.1 9.1 6.1 0.0 3.6 3 0 0 3 3 3 0 B12 binding domain Aldedh PF00171.17 EWM29399.1 - 1.3e-136 455.6 2.4 1.7e-136 455.2 0.4 1.8 2 0 0 2 2 2 1 Aldehyde dehydrogenase family BCIP PF13862.1 EWM29400.1 - 3.6e-26 91.8 0.0 6.6e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Hamartin PF04388.7 EWM29400.1 - 0.069 11.8 0.9 0.18 10.4 0.6 1.5 1 1 0 1 1 1 0 Hamartin protein tRNA_Me_trans PF03054.11 EWM29401.1 - 2.2e-113 378.4 0.0 4.8e-113 377.3 0.0 1.5 1 1 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.16 EWM29401.1 - 9.8e-06 25.2 0.0 1.4e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase ThiI PF02568.9 EWM29401.1 - 7e-05 22.3 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) NAD_synthase PF02540.12 EWM29401.1 - 0.00012 21.0 0.0 0.00036 19.4 0.0 1.7 2 0 0 2 2 2 1 NAD synthase QueC PF06508.8 EWM29401.1 - 0.0063 15.8 0.0 0.018 14.3 0.0 1.7 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC MEKHLA PF08670.6 EWM29403.1 - 2.8e-41 140.4 0.0 3.6e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 MEKHLA domain Sigma70_r4 PF04545.11 EWM29404.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 Myb_DNA-binding PF00249.26 EWM29405.1 - 2.6e-12 46.5 0.3 5.4e-12 45.5 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EWM29405.1 - 0.03 14.4 0.3 0.03 14.4 0.2 2.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain PAS_9 PF13426.1 EWM29406.1 - 1.9e-18 66.7 0.0 4.3e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 PAS domain bZIP_2 PF07716.10 EWM29406.1 - 5.4e-07 29.3 12.9 5.4e-07 29.3 8.9 2.1 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 EWM29406.1 - 5.9e-05 22.9 10.4 5.9e-05 22.9 7.2 2.3 3 0 0 3 3 3 1 bZIP transcription factor PAS_4 PF08448.5 EWM29406.1 - 0.00058 19.8 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.6 EWM29406.1 - 0.026 14.5 0.0 0.11 12.5 0.0 2.0 1 1 0 1 1 1 0 PAS fold PAS PF00989.19 EWM29406.1 - 0.04 13.7 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 PAS fold RR_TM4-6 PF06459.7 EWM29406.1 - 0.88 9.4 6.2 1.5 8.6 4.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 F-box-like PF12937.2 EWM29407.1 - 0.055 13.1 0.0 0.093 12.4 0.0 1.3 1 0 0 1 1 1 0 F-box-like TPR_11 PF13414.1 EWM29408.1 - 1.2e-51 172.1 33.7 5.7e-18 64.3 3.0 6.5 5 2 3 8 8 8 6 TPR repeat TPR_1 PF00515.23 EWM29408.1 - 8.5e-44 145.4 27.3 1.8e-08 33.5 0.2 8.8 8 1 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.12 EWM29408.1 - 1.2e-35 118.4 31.7 1.6e-07 30.7 0.1 9.7 9 1 0 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.1 EWM29408.1 - 7.1e-26 90.2 36.4 3.2e-06 27.6 0.9 7.7 4 3 2 8 8 8 5 Tetratricopeptide repeat DnaJ PF00226.26 EWM29408.1 - 9.6e-26 89.3 3.5 3.9e-25 87.3 2.3 2.2 2 0 0 2 2 1 1 DnaJ domain TPR_19 PF14559.1 EWM29408.1 - 8.4e-20 70.8 29.6 1.2e-05 25.4 0.0 6.8 5 2 2 7 7 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 EWM29408.1 - 1.7e-19 68.5 28.8 7.1e-05 23.0 0.1 9.5 4 4 7 11 11 11 5 Tetratricopeptide repeat TPR_8 PF13181.1 EWM29408.1 - 1e-16 59.3 14.6 0.00071 19.1 0.0 8.4 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_9 PF13371.1 EWM29408.1 - 2.2e-15 56.2 21.2 4.4e-07 29.6 0.1 6.5 4 3 4 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.1 EWM29408.1 - 1.5e-13 50.4 27.4 8.4e-05 22.4 0.7 6.7 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 EWM29408.1 - 7.4e-13 47.2 15.0 0.015 15.0 0.0 7.3 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.1 EWM29408.1 - 2.8e-12 45.8 17.4 0.00049 20.0 0.0 8.3 10 0 0 10 10 8 3 Tetratricopeptide repeat Apc3 PF12895.2 EWM29408.1 - 7.1e-11 42.0 22.3 6.6e-05 22.9 0.7 4.9 4 1 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 EWM29408.1 - 1.6e-08 34.3 16.1 0.0013 18.5 0.1 6.8 8 1 1 9 9 8 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 EWM29408.1 - 2.3e-06 27.6 19.9 0.0031 17.8 0.0 7.5 8 1 0 8 8 7 2 Tetratricopeptide repeat TPR_3 PF07720.7 EWM29408.1 - 3e-05 23.6 3.6 0.044 13.5 0.0 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat DUF3856 PF12968.2 EWM29408.1 - 0.05 13.4 8.4 7.6 6.3 0.3 6.0 5 2 0 5 5 5 0 Domain of Unknown Function (DUF3856) TOM20_plant PF06552.7 EWM29408.1 - 0.07 12.7 4.6 3.9 7.0 0.0 3.6 4 0 0 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 V-SNARE PF05008.10 EWM29408.1 - 0.64 10.2 10.2 0.46 10.6 1.2 3.4 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus TPR_10 PF13374.1 EWM29408.1 - 0.99 9.4 13.8 7 6.7 0.1 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.9 EWM29408.1 - 2.2 8.9 10.3 2.3 8.9 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat SAP PF02037.22 EWM29409.1 - 0.00075 18.9 1.2 0.0018 17.7 0.8 1.7 1 0 0 1 1 1 1 SAP domain Telomere_Sde2_2 PF13297.1 EWM29409.1 - 0.071 12.3 3.7 3.9 6.8 0.0 2.8 1 1 1 2 2 2 0 Telomere stability C-terminal Pro_isomerase PF00160.16 EWM29410.1 - 1.3e-20 74.2 0.0 2.1e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pyr_redox_2 PF07992.9 EWM29411.1 - 6.1e-41 140.5 2.1 8.5e-41 140.0 1.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EWM29411.1 - 3.5e-32 110.7 0.2 1e-31 109.2 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EWM29411.1 - 1.1e-19 70.5 7.4 1.3e-18 67.1 0.8 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EWM29411.1 - 1.8e-13 51.0 0.8 1.1e-12 48.4 0.5 2.3 2 1 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EWM29411.1 - 2.9e-05 23.1 7.5 0.0014 17.5 2.4 2.5 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 EWM29411.1 - 3.6e-05 23.0 1.6 5.5e-05 22.4 1.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EWM29411.1 - 5.3e-05 21.8 4.0 0.016 13.6 0.7 2.7 3 0 0 3 3 3 2 HI0933-like protein DAO PF01266.19 EWM29411.1 - 9.6e-05 21.4 0.2 9.6e-05 21.4 0.1 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EWM29411.1 - 0.00022 21.4 0.7 1 9.6 0.1 2.6 3 0 0 3 3 2 2 Putative NAD(P)-binding Thi4 PF01946.12 EWM29411.1 - 0.00036 19.6 1.2 0.00036 19.6 0.8 1.9 2 1 0 2 2 2 1 Thi4 family GIDA PF01134.17 EWM29411.1 - 0.002 17.0 1.7 0.002 17.0 1.2 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EWM29411.1 - 0.0021 17.1 4.2 0.041 12.9 0.2 2.3 2 0 0 2 2 2 2 FAD binding domain K_oxygenase PF13434.1 EWM29411.1 - 0.0025 16.7 0.0 0.0062 15.5 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.14 EWM29411.1 - 0.012 14.8 1.8 3.3 6.8 0.0 2.9 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 EWM29411.1 - 0.015 15.0 0.3 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EWM29411.1 - 0.016 15.1 3.2 0.016 15.1 2.2 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain XdhC_C PF13478.1 EWM29411.1 - 0.02 15.2 0.1 6.9 6.9 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain DUF2330 PF10092.4 EWM29411.1 - 0.079 11.7 0.1 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2330) 3HCDH_N PF02737.13 EWM29411.1 - 0.098 12.3 5.3 2.4 7.7 0.1 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EWM29411.1 - 0.14 12.2 0.5 18 5.4 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.16 EWM29411.1 - 0.4 10.2 3.0 17 4.8 0.1 2.8 2 1 1 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain FA_desaturase PF00487.19 EWM29412.1 - 3.4e-29 102.0 19.0 3.4e-29 102.0 13.2 1.6 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EWM29412.1 - 5.2e-14 51.7 0.0 1.4e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain APC10 PF03256.11 EWM29413.1 - 8.9e-65 217.9 0.0 1.1e-64 217.6 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Ank_2 PF12796.2 EWM29414.1 - 1.8e-33 114.6 0.1 1.4e-15 57.3 0.0 3.8 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 EWM29414.1 - 1.6e-26 90.7 12.1 6.2e-07 28.9 0.8 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 EWM29414.1 - 1.5e-23 82.7 10.1 1.4e-09 38.1 0.2 5.3 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EWM29414.1 - 5.1e-19 67.8 5.3 1.9e-05 24.7 0.4 4.7 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM29414.1 - 1.1e-17 62.3 2.2 0.0022 18.0 0.2 6.5 6 0 0 6 6 6 3 Ankyrin repeat Peptidase_M22 PF00814.20 EWM29415.1 - 1.2e-68 231.5 0.4 3.5e-65 220.1 0.2 3.0 1 1 0 1 1 1 1 Glycoprotease family CmcH_NodU PF02543.10 EWM29415.1 - 0.061 12.4 0.0 0.091 11.8 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase LSM14 PF12701.2 EWM29417.1 - 7.7e-30 102.5 0.0 1.5e-29 101.6 0.0 1.4 1 1 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.1 EWM29417.1 - 2.7e-06 27.1 0.0 5.3e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain FDF PF09532.5 EWM29417.1 - 0.00029 21.3 0.3 0.0007 20.1 0.0 1.7 2 0 0 2 2 2 1 FDF domain MSA-2c PF12238.3 EWM29417.1 - 0.23 11.0 2.6 0.34 10.5 1.8 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c HpaP PF09483.5 EWM29417.1 - 5.1 7.0 10.7 7.4 6.4 7.4 1.1 1 0 0 1 1 1 0 Type III secretion protein (HpaP) Abhydrolase_5 PF12695.2 EWM29418.1 - 4.5e-08 32.9 0.1 7.8e-08 32.1 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EWM29418.1 - 5.1e-05 23.2 4.6 0.00015 21.7 1.5 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EWM29418.1 - 6.4e-05 23.2 0.6 6.4e-05 23.2 0.4 1.8 2 0 0 2 2 2 1 Thioesterase domain START PF01852.14 EWM29419.1 - 4.3e-17 62.1 0.1 1.6e-11 43.9 0.0 2.5 2 0 0 2 2 2 2 START domain ACBP PF00887.14 EWM29419.1 - 5.3e-14 51.6 0.0 9.5e-14 50.8 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein PH PF00169.24 EWM29419.1 - 3.3e-10 40.1 0.0 5.4e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 PH domain 2-oxoacid_dh PF00198.18 EWM29419.1 - 4e-07 29.5 0.1 3.1e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) PH_11 PF15413.1 EWM29419.1 - 2.3e-06 27.8 0.2 0.00012 22.2 0.1 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EWM29419.1 - 0.0044 17.0 0.1 0.35 10.9 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain Pkinase PF00069.20 EWM29420.1 - 3.3e-20 72.3 0.0 4.6e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM29420.1 - 0.00018 20.6 0.0 0.00024 20.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EWM29420.1 - 0.0036 16.3 0.0 0.0045 16.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Med3 PF11593.3 EWM29421.1 - 8 5.5 10.2 9.7 5.3 7.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PTE PF02126.13 EWM29422.1 - 2.2e-09 36.7 0.0 6.7e-09 35.1 0.0 1.8 2 0 0 2 2 2 1 Phosphotriesterase family Glyco_trans_4_4 PF13579.1 EWM29422.1 - 0.18 11.9 1.8 1.7 8.7 0.1 2.8 2 1 1 3 3 3 0 Glycosyl transferase 4-like domain NAD_Gly3P_dh_C PF07479.9 EWM29423.1 - 3.3e-48 163.1 0.0 6.6e-48 162.2 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 EWM29423.1 - 5.2e-47 159.4 0.0 8e-47 158.8 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 EWM29423.1 - 6.8e-05 23.2 0.0 0.001 19.4 0.0 2.5 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 EWM29423.1 - 0.0023 18.2 0.0 0.0047 17.2 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Pkinase PF00069.20 EWM29424.1 - 2.6e-30 105.4 0.0 3.9e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM29424.1 - 9.2e-18 64.2 0.1 1.3e-17 63.7 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EWM29424.1 - 0.0084 15.8 0.1 0.021 14.5 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EWM29424.1 - 0.0098 15.2 0.2 0.019 14.3 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Acyl-CoA_dh_1 PF00441.19 EWM29425.1 - 6.1e-37 127.0 2.3 9.6e-37 126.3 1.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EWM29425.1 - 1.1e-29 103.2 0.0 2.6e-29 102.0 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EWM29425.1 - 3.1e-16 59.8 0.2 7.1e-16 58.6 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EWM29425.1 - 1.5e-15 56.4 1.1 3.5e-15 55.2 0.8 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Lyase_aromatic PF00221.14 EWM29427.1 - 1.9e-22 79.4 0.8 5.9e-16 57.9 0.0 2.8 1 1 2 3 3 3 2 Aromatic amino acid lyase Fer2_3 PF13085.1 EWM29428.1 - 2.5e-31 107.7 0.0 4.6e-31 106.8 0.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EWM29428.1 - 5.2e-10 39.5 6.0 5.2e-10 39.5 4.2 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EWM29428.1 - 5.5e-10 39.1 3.6 5.5e-10 39.1 2.5 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_18 PF13746.1 EWM29428.1 - 1.4e-06 28.5 1.9 1.4e-06 28.5 1.3 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 EWM29428.1 - 4.6e-06 26.8 7.3 0.0084 16.3 0.8 3.1 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EWM29428.1 - 2.6e-05 23.9 5.2 2.6e-05 23.9 3.6 2.5 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 EWM29428.1 - 0.001 18.7 2.7 0.006 16.3 0.1 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.2 EWM29428.1 - 0.0012 19.2 8.3 0.0012 19.2 5.7 2.9 1 1 2 3 3 3 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 EWM29428.1 - 2.6 8.1 19.1 0.44 10.5 3.4 3.5 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_4 PF12800.2 EWM29428.1 - 7.6 7.1 16.7 1.2 9.6 1.5 3.4 3 0 0 3 3 3 0 4Fe-4S binding domain PGI PF00342.14 EWM29429.1 - 6.7e-174 578.8 0.0 9.1e-174 578.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoglucose isomerase NAD_binding_5 PF07994.7 EWM29429.1 - 4.6e-47 160.9 0.0 8.2e-47 160.1 0.0 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase PfkB PF00294.19 EWM29429.1 - 3.6e-19 69.0 0.8 5.1e-12 45.5 0.1 2.4 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Inos-1-P_synth PF01658.12 EWM29429.1 - 5.1e-19 68.1 0.0 8.8e-19 67.3 0.0 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase MinE PF03776.9 EWM29430.1 - 6.4e-15 54.4 0.3 9e-15 53.9 0.2 1.2 1 0 0 1 1 1 1 Septum formation topological specificity factor MinE ubiquitin PF00240.18 EWM29431.1 - 2.5e-35 119.6 0.9 5e-35 118.7 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EWM29431.1 - 1.6e-20 72.5 0.7 1.6e-20 72.5 0.5 1.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_S27 PF01599.14 EWM29431.1 - 1.4e-19 69.6 4.1 2.5e-19 68.8 2.9 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Ubiquitin_2 PF14560.1 EWM29431.1 - 1e-07 32.1 0.2 4.8e-06 26.7 0.1 2.7 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EWM29431.1 - 0.00026 20.7 0.0 0.00038 20.1 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EWM29431.1 - 0.00032 20.5 0.5 0.00073 19.4 0.3 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EWM29431.1 - 0.0019 18.3 0.5 0.0026 17.9 0.3 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Plexin_cytopl PF08337.7 EWM29431.1 - 0.0041 15.5 1.6 0.43 8.8 0.1 2.7 2 1 1 3 3 3 2 Plexin cytoplasmic RasGAP domain TUG-UBL1 PF11470.3 EWM29431.1 - 0.05 13.5 1.0 0.065 13.1 0.0 1.7 2 0 0 2 2 2 0 GLUT4 regulating protein TUG DZR PF12773.2 EWM29431.1 - 0.079 12.7 0.2 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Double zinc ribbon DUF2870 PF11069.3 EWM29431.1 - 0.093 12.7 0.2 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) Nudix_N_2 PF14803.1 EWM29431.1 - 0.94 9.2 4.3 3 7.6 2.7 2.1 1 1 0 1 1 1 0 Nudix N-terminal TOBE PF03459.12 EWM29432.1 - 0.42 10.7 2.1 2 8.5 0.1 2.4 2 0 0 2 2 2 0 TOBE domain DIRP PF06584.8 EWM29433.1 - 2.9 7.7 5.8 0.21 11.4 0.5 1.8 2 0 0 2 2 2 0 DIRP tRNA-synt_2b PF00587.20 EWM29435.1 - 0.00029 20.4 0.0 0.0003 20.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_His PF13393.1 EWM29435.1 - 0.0044 16.1 0.0 0.005 15.9 0.0 1.0 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.15 EWM29436.1 - 2e-10 40.4 0.0 2.8e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.2 EWM29436.1 - 0.029 13.4 0.0 0.038 13.1 0.0 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs NAD_kinase PF01513.16 EWM29436.1 - 0.06 12.1 0.0 5.2 5.7 0.0 2.0 2 0 0 2 2 2 0 ATP-NAD kinase AP_endonuc_2 PF01261.19 EWM29436.1 - 0.08 12.2 0.0 0.086 12.1 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Amidohydro_2 PF04909.9 EWM29438.1 - 2.6e-07 30.5 0.0 3e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase ORC4_C PF14629.1 EWM29439.1 - 1.3e-10 41.0 0.1 2.6e-10 40.0 0.1 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 EWM29439.1 - 1.8e-09 37.8 0.0 6.8e-09 35.9 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EWM29439.1 - 2.7e-07 30.8 0.0 6e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EWM29439.1 - 1.2e-06 28.7 0.0 5.7e-06 26.5 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EWM29439.1 - 0.0012 18.6 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase DUF815 PF05673.8 EWM29439.1 - 0.011 14.7 0.0 0.025 13.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DAP3 PF10236.4 EWM29439.1 - 0.013 14.4 0.0 0.046 12.6 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_5 PF07728.9 EWM29439.1 - 0.028 14.1 0.0 0.41 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EWM29439.1 - 0.065 12.9 0.0 0.22 11.2 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain 2-Hacid_dh_C PF02826.14 EWM29440.1 - 3.1e-51 173.0 0.0 5.1e-51 172.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EWM29440.1 - 9.9e-26 89.7 0.0 1.3e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EWM29440.1 - 1.1e-07 31.8 0.2 1.9e-06 27.8 0.0 2.5 2 1 1 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 EWM29440.1 - 1.3e-05 25.1 0.4 2.7e-05 24.0 0.3 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Semialdhyde_dh PF01118.19 EWM29440.1 - 0.028 14.7 2.2 1.5 9.1 0.0 2.6 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EWM29440.1 - 0.034 14.5 0.1 0.54 10.7 0.0 2.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Methyltransf_18 PF12847.2 EWM29440.1 - 0.054 14.0 0.0 0.37 11.3 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain IlvN PF07991.7 EWM29440.1 - 0.063 12.6 0.0 0.3 10.4 0.0 2.0 2 1 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Glyco_transf_22 PF03901.12 EWM29441.1 - 9.7e-75 252.1 0.3 1.5e-74 251.4 0.2 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family ELO PF01151.13 EWM29442.1 - 9.9e-67 224.8 14.4 1.4e-66 224.3 10.0 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Nol1_Nop2_Fmu PF01189.12 EWM29444.1 - 1.3e-16 60.8 0.0 7.2e-08 32.1 0.0 2.8 2 1 0 2 2 2 2 NOL1/NOP2/sun family Methyltransf_18 PF12847.2 EWM29444.1 - 5.5e-07 30.1 0.2 6.6e-06 26.6 0.1 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM29444.1 - 2.4e-06 27.1 0.0 0.00034 20.2 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM29444.1 - 1.3e-05 25.1 0.8 5e-05 23.3 0.6 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM29444.1 - 0.00024 21.5 0.3 0.04 14.4 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM29444.1 - 0.0017 18.0 0.1 2.3 7.9 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.13 EWM29444.1 - 0.0023 17.0 0.0 0.036 13.1 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EWM29444.1 - 0.0071 16.6 0.8 0.026 14.8 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 EWM29444.1 - 0.02 14.9 0.2 0.058 13.3 0.1 1.8 2 0 0 2 2 2 0 FtsJ-like methyltransferase MTS PF05175.9 EWM29444.1 - 0.024 14.0 0.0 0.28 10.5 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain AMP-binding PF00501.23 EWM29446.1 - 7.5e-80 268.3 0.0 1e-79 267.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PEP_mutase PF13714.1 EWM29447.1 - 1.2e-55 188.3 0.0 1.6e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EWM29447.1 - 2.4e-14 52.4 0.6 4.3e-14 51.6 0.4 1.4 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.10 EWM29447.1 - 0.0088 15.1 0.0 0.023 13.8 0.0 1.6 2 1 1 3 3 3 1 Ketopantoate hydroxymethyltransferase WD40 PF00400.27 EWM29450.1 - 3.1e-41 137.8 8.1 5.4e-11 41.9 0.0 7.5 8 1 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 EWM29450.1 - 0.0016 16.7 0.1 0.087 10.9 0.0 2.1 1 1 0 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 EWM29450.1 - 0.018 14.7 0.0 8.1 6.1 0.0 2.6 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EWM29450.1 - 0.1 11.3 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 Coatomer WD associated region PQQ_2 PF13360.1 EWM29450.1 - 0.1 12.0 0.0 0.29 10.5 0.0 1.7 2 1 0 2 2 2 0 PQQ-like domain Rad60-SLD PF11976.3 EWM29451.1 - 3e-18 65.2 1.0 4.8e-18 64.6 0.7 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EWM29451.1 - 3.9e-08 32.5 0.9 6e-08 31.9 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Integrin_b_cyt PF08725.6 EWM29451.1 - 0.025 13.9 0.1 0.044 13.1 0.1 1.4 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain RPE65 PF03055.10 EWM29452.1 - 6.5e-93 311.9 0.0 8.5e-93 311.5 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein RPE65 PF03055.10 EWM29453.1 - 3.3e-50 171.0 0.0 3.8e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein COX16 PF14138.1 EWM29454.1 - 0.12 12.5 1.1 0.33 11.1 0.8 1.7 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 SAP PF02037.22 EWM29456.1 - 1.7e-10 40.1 2.6 8e-05 22.0 0.2 3.6 3 0 0 3 3 3 2 SAP domain DnaJ PF00226.26 EWM29456.1 - 3.3e-09 36.3 1.0 4.8e-09 35.8 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain UPF0547 PF10571.4 EWM29456.1 - 2.1e-05 24.1 0.0 0.028 14.1 0.0 2.9 2 1 0 2 2 2 1 Uncharacterised protein family UPF0547 zf-C2HC_2 PF13913.1 EWM29456.1 - 0.26 10.9 9.8 0.029 14.0 1.3 2.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF329 PF03884.9 EWM29456.1 - 1.2 8.6 6.4 18 4.9 0.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF329) zinc_ribbon_5 PF13719.1 EWM29456.1 - 3.7 7.2 7.3 28 4.4 0.1 3.7 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EWM29456.1 - 4.1 7.1 6.9 31 4.3 0.1 3.8 3 0 0 3 3 3 0 zinc-ribbon domain DUF1731 PF08338.6 EWM29457.1 - 1.2e-15 56.6 0.3 2.7e-15 55.5 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) Epimerase PF01370.16 EWM29457.1 - 1.5e-08 34.3 0.0 1.1e-07 31.6 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EWM29457.1 - 1.8e-07 31.3 0.4 2.9e-07 30.6 0.3 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EWM29457.1 - 0.0014 18.5 1.5 0.63 9.9 0.8 2.3 1 1 1 2 2 2 2 short chain dehydrogenase RmlD_sub_bind PF04321.12 EWM29457.1 - 0.069 12.0 0.2 0.13 11.0 0.1 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EWM29457.1 - 0.11 11.4 0.6 7.4 5.3 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Ldh_1_N PF00056.18 EWM29457.1 - 0.26 11.0 1.3 0.87 9.4 0.9 1.9 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain zf-MYND PF01753.13 EWM29459.1 - 9.1e-15 54.2 41.7 5.6e-09 35.7 12.3 3.7 5 0 0 5 5 5 2 MYND finger tRNA-synt_1b PF00579.20 EWM29460.1 - 5.8e-89 298.0 0.0 7.6e-89 297.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) UQ_con PF00179.21 EWM29462.1 - 1.9e-11 43.5 0.0 3.1e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme dCMP_cyt_deam_1 PF00383.17 EWM29463.1 - 1.1e-05 25.0 0.0 2.3e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_1 PF00383.17 EWM29464.1 - 4.3e-25 87.3 0.0 7.2e-25 86.6 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region PBP PF01161.15 EWM29466.1 - 7.6e-19 67.9 0.1 2.1e-11 43.8 0.0 2.1 2 0 0 2 2 2 2 Phosphatidylethanolamine-binding protein MMPL PF03176.10 EWM29469.1 - 1.8e-43 148.5 16.9 3.4e-43 147.6 11.7 1.3 1 1 0 1 1 1 1 MMPL family MRAP PF15183.1 EWM29469.1 - 0.076 12.6 0.2 0.19 11.3 0.1 1.6 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family NinG PF05766.7 EWM29469.1 - 0.076 12.7 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein WD40 PF00400.27 EWM29470.1 - 2.2e-13 49.4 0.8 8.4e-07 28.6 0.0 6.2 7 1 0 7 7 7 2 WD domain, G-beta repeat DUF972 PF06156.8 EWM29470.1 - 0.00053 20.2 0.6 0.0011 19.3 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF972) Lactonase PF10282.4 EWM29470.1 - 0.13 11.2 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller bZIP_1 PF00170.16 EWM29470.1 - 0.23 11.4 3.3 0.7 9.8 0.9 2.2 1 1 1 2 2 2 0 bZIP transcription factor DUF904 PF06005.7 EWM29470.1 - 0.25 11.6 4.1 0.58 10.4 2.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF904) bZIP_2 PF07716.10 EWM29470.1 - 0.5 10.2 2.6 5.2 6.9 0.7 2.2 2 0 0 2 2 2 0 Basic region leucine zipper FAD_binding_6 PF00970.19 EWM29473.1 - 1.3e-31 108.6 0.0 2.3e-31 107.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EWM29473.1 - 5.5e-31 107.3 0.0 1.2e-30 106.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EWM29473.1 - 7.7e-06 25.8 0.0 0.00013 21.9 0.0 2.2 1 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EWM29473.1 - 0.0087 16.0 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain Aida_C2 PF14186.1 EWM29473.1 - 0.043 13.0 0.0 0.093 11.9 0.0 1.4 1 0 0 1 1 1 0 Cytoskeletal adhesion PB1 PF00564.19 EWM29473.1 - 0.12 12.0 0.1 2.9 7.6 0.0 2.5 2 0 0 2 2 2 0 PB1 domain PCI PF01399.22 EWM29476.1 - 9.4e-13 48.4 0.3 1.9e-12 47.3 0.2 1.5 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 EWM29476.1 - 1.1e-08 34.9 0.2 2.2e-08 33.9 0.1 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 DUF2379 PF09543.5 EWM29476.1 - 0.063 13.2 0.1 0.17 11.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) DUF2379 PF09543.5 EWM29477.1 - 0.063 13.2 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) UBN2_2 PF14227.1 EWM29479.1 - 1.5e-07 30.9 0.2 2.2e-07 30.4 0.2 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EWM29479.1 - 8.9e-07 28.7 0.0 1.6e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF1759 PF03564.10 EWM29479.1 - 0.00064 19.5 0.1 0.00096 18.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) Myb_DNA-binding PF00249.26 EWM29480.1 - 1.6e-29 101.7 3.9 3.2e-11 43.1 0.1 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EWM29480.1 - 3.3e-26 91.1 1.6 3.3e-13 49.5 0.1 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Helicase_C PF00271.26 EWM29482.1 - 9e-13 47.8 0.0 1.8e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PSK_trans_fac PF07704.6 EWM29482.1 - 0.31 11.7 2.3 2.2 9.0 0.0 2.7 3 0 0 3 3 3 0 Rv0623-like transcription factor VWA_2 PF13519.1 EWM29484.1 - 2.8e-05 24.3 0.0 3.4e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Ku_N PF03731.10 EWM29484.1 - 0.00048 19.6 0.0 0.0012 18.3 0.0 1.6 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain CYTL1 PF15153.1 EWM29484.1 - 0.023 14.4 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 Cytokine-like protein 1 DUF3079 PF11278.3 EWM29484.1 - 0.081 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3079) Helicase_C PF00271.26 EWM29485.1 - 1e-19 70.1 0.0 1.3e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TLD PF07534.11 EWM29486.1 - 0.0039 17.1 0.0 0.0085 16.0 0.0 1.5 1 0 0 1 1 1 1 TLD TLD PF07534.11 EWM29487.1 - 0.0035 17.3 0.0 0.0074 16.2 0.0 1.5 1 0 0 1 1 1 1 TLD Bromodomain PF00439.20 EWM29490.1 - 6e-18 64.5 0.0 1.3e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Bromodomain zf-TAZ PF02135.11 EWM29490.1 - 6.2e-17 61.3 13.1 2.1e-16 59.7 9.1 2.0 1 0 0 1 1 1 1 TAZ zinc finger PHD PF00628.24 EWM29490.1 - 7.3e-08 31.9 3.8 2.3e-07 30.3 2.6 1.9 1 0 0 1 1 1 1 PHD-finger DUF1423 PF07227.6 EWM29490.1 - 0.00095 17.9 1.0 0.00095 17.9 0.7 3.1 4 0 0 4 4 4 1 Protein of unknown function (DUF1423) zf-TAZ PF02135.11 EWM29492.1 - 3e-06 27.1 7.6 5.2e-06 26.3 5.3 1.3 1 0 0 1 1 1 1 TAZ zinc finger PPR PF01535.15 EWM29493.1 - 0.00078 19.2 0.0 0.41 10.7 0.0 2.4 2 0 0 2 2 2 2 PPR repeat PPR_1 PF12854.2 EWM29493.1 - 0.0011 18.3 0.0 0.14 11.6 0.0 2.3 2 0 0 2 2 2 2 PPR repeat PPR_2 PF13041.1 EWM29493.1 - 0.0069 16.3 0.0 2.8 7.9 0.0 2.3 2 0 0 2 2 2 2 PPR repeat family PPR_3 PF13812.1 EWM29493.1 - 0.0076 16.4 0.2 1.2 9.6 0.0 2.8 3 0 0 3 3 3 1 Pentatricopeptide repeat domain Colicin_C PF12106.3 EWM29493.1 - 0.63 9.6 2.9 1.4 8.5 2.0 1.6 1 0 0 1 1 1 0 Colicin C terminal ribonuclease domain Ctr PF04145.10 EWM29496.1 - 5.4e-18 65.4 10.7 1.6e-17 63.8 7.4 1.7 1 1 0 1 1 1 1 Ctr copper transporter family Ctr PF04145.10 EWM29497.1 - 3.4e-18 66.0 10.9 1.1e-17 64.3 7.6 1.7 1 1 0 1 1 1 1 Ctr copper transporter family DUF1426 PF07234.6 EWM29497.1 - 0.16 11.7 0.6 1.2 8.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1426) PPR_2 PF13041.1 EWM29502.1 - 3.5e-19 68.5 0.0 0.00033 20.5 0.0 5.8 4 2 2 6 6 6 6 PPR repeat family PPR PF01535.15 EWM29502.1 - 4.6e-17 60.7 0.0 6e-05 22.7 0.0 5.1 5 0 0 5 5 5 4 PPR repeat PPR_3 PF13812.1 EWM29502.1 - 9.5e-17 59.8 4.1 0.00012 22.1 0.0 6.9 7 0 0 7 7 7 3 Pentatricopeptide repeat domain PPR_1 PF12854.2 EWM29502.1 - 5.3e-12 45.0 0.0 0.0006 19.2 0.0 4.9 5 0 0 5 5 5 3 PPR repeat TPR_14 PF13428.1 EWM29502.1 - 3.7e-07 30.1 7.7 0.0072 16.8 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EWM29502.1 - 0.009 15.9 1.9 16 5.5 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EWM29502.1 - 0.011 16.3 7.3 16 6.3 0.3 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.12 EWM29502.1 - 0.014 15.6 0.0 0.041 14.1 0.0 1.7 1 0 0 1 1 1 0 Bacterial transcriptional activator domain ACC_epsilon PF13822.1 EWM29502.1 - 0.028 14.7 3.6 9.6 6.6 0.0 3.7 3 0 0 3 3 3 0 Acyl-CoA carboxylase epsilon subunit TPR_4 PF07721.9 EWM29502.1 - 0.16 12.4 7.3 6 7.6 0.5 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat JAB PF01398.16 EWM29503.1 - 1.6e-23 82.6 0.0 2.2e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease VDE PF07137.6 EWM29505.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Violaxanthin de-epoxidase (VDE) NARP1 PF12569.3 EWM29506.1 - 0.29 9.8 2.9 0.4 9.3 2.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF755 PF05501.6 EWM29506.1 - 0.5 10.4 13.1 0.82 9.7 9.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) CS PF04969.11 EWM29507.1 - 1.6e-12 47.7 0.1 1.6e-12 47.7 0.1 1.4 2 0 0 2 2 2 1 CS domain Fork_head_N PF08430.7 EWM29507.1 - 0.38 11.1 10.6 0.52 10.7 7.4 1.1 1 0 0 1 1 1 0 Forkhead N-terminal region Med15 PF09606.5 EWM29507.1 - 1.3 7.1 3.1 1.5 6.9 2.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RNA_pol_A_bac PF01000.21 EWM29508.1 - 4.8e-08 33.1 0.0 2.5e-07 30.8 0.0 2.1 2 1 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EWM29508.1 - 4.5e-05 22.4 0.0 4.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain CLIP PF12032.3 EWM29508.1 - 0.0021 18.1 0.2 0.016 15.2 0.0 2.2 2 0 0 2 2 2 1 Regulatory CLIP domain of proteinases Fer4_7 PF12838.2 EWM29508.1 - 0.0078 16.5 2.4 0.018 15.3 1.7 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EWM29508.1 - 0.091 13.0 3.4 0.17 12.1 2.3 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain RNA_pol_A_bac PF01000.21 EWM29509.1 - 3.2e-11 43.3 0.0 5.2e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EWM29509.1 - 4e-09 35.4 0.0 4.1e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain PPP1R35_C PF15503.1 EWM29509.1 - 0.1 12.1 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 35 C-terminus RabGAP-TBC PF00566.13 EWM29511.1 - 7.4e-38 130.1 0.0 1.1e-37 129.5 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CHAD PF05235.9 EWM29511.1 - 0.011 15.2 2.8 0.011 15.2 1.9 1.7 2 0 0 2 2 2 0 CHAD domain HD_3 PF13023.1 EWM29513.1 - 4.5e-42 143.6 0.2 5.8e-42 143.2 0.1 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 EWM29513.1 - 2.7e-05 24.1 0.3 4e-05 23.6 0.2 1.2 1 0 0 1 1 1 1 HD domain DUF3323 PF11796.3 EWM29513.1 - 0.09 12.0 0.2 1.7 7.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) HPP PF04982.8 EWM29513.1 - 0.13 12.0 0.9 0.25 11.1 0.5 1.5 1 1 0 1 1 1 0 HPP family EST1_DNA_bind PF10373.4 EWM29514.1 - 9.2e-15 54.5 0.0 2.5e-14 53.1 0.0 1.6 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain TPR_12 PF13424.1 EWM29514.1 - 0.034 14.0 1.0 2.3 8.2 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat Fer2 PF00111.22 EWM29515.1 - 1.3e-10 40.8 1.3 2.1e-10 40.1 0.9 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain ECH PF00378.15 EWM29516.1 - 3.6e-48 163.8 0.0 4.2e-48 163.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Sec63 PF02889.11 EWM29517.1 - 2e-34 119.2 0.0 3.1e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 EWM29517.1 - 4.3e-20 71.2 0.1 8.4e-20 70.2 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain PrgI PF12666.2 EWM29517.1 - 0.3 11.2 2.2 2.8 8.1 0.0 2.6 2 0 0 2 2 2 0 PrgI family protein DUF4644 PF15486.1 EWM29518.1 - 1.5 8.7 4.9 2.4 8.0 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4644) Cupin_3 PF05899.7 EWM29519.1 - 0.13 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Proteasome PF00227.21 EWM29521.1 - 2.9e-26 91.9 0.1 5.4e-22 77.9 0.0 2.0 2 0 0 2 2 2 2 Proteasome subunit Proteasome PF00227.21 EWM29522.1 - 1.1e-09 37.8 0.1 2.5e-05 23.6 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit FAD_binding_3 PF01494.14 EWM29523.1 - 1.1e-20 74.0 0.4 8e-10 38.2 0.2 2.4 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EWM29523.1 - 1.7e-06 27.1 0.1 3.3e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EWM29523.1 - 0.009 16.0 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 EWM29523.1 - 0.015 14.1 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Pyr_redox_2 PF07992.9 EWM29523.1 - 0.017 14.9 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EWM29523.1 - 0.051 12.4 2.5 0.15 10.9 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Methyltransf_11 PF08241.7 EWM29524.1 - 2e-14 53.8 0.0 3.7e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM29524.1 - 9.7e-12 45.1 0.0 2.1e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM29524.1 - 4.9e-10 39.1 0.0 6.5e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EWM29524.1 - 6.2e-08 32.0 0.0 1.7e-07 30.5 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 EWM29524.1 - 6.4e-08 32.4 0.0 8.6e-08 32.0 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM29524.1 - 2.3e-06 28.0 0.0 5.2e-06 26.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM29524.1 - 4.9e-06 26.5 0.4 1.4e-05 25.1 0.1 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM29524.1 - 3.6e-05 24.2 0.0 7.9e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EWM29524.1 - 0.0036 16.9 0.0 0.005 16.4 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_2 PF00891.13 EWM29524.1 - 0.017 14.3 0.0 0.028 13.6 0.0 1.5 1 1 0 1 1 1 0 O-methyltransferase MetW PF07021.7 EWM29524.1 - 0.1 11.9 0.0 0.22 10.9 0.0 1.5 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Kp4 PF09044.5 EWM29525.1 - 0.093 12.5 1.7 0.21 11.3 0.3 2.1 1 1 1 2 2 2 0 Kp4 Pyr_redox_dim PF02852.17 EWM29526.1 - 3.2e-19 68.9 0.0 9.4e-19 67.4 0.0 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 EWM29526.1 - 5.7e-18 65.5 0.0 1.5e-17 64.1 0.0 1.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EWM29526.1 - 8.4e-11 42.1 1.2 7.8e-07 29.4 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EWM29526.1 - 2.7e-06 27.6 0.0 6.3e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EWM29526.1 - 9.6e-05 21.6 0.0 0.018 14.2 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.19 EWM29526.1 - 0.00013 21.0 0.1 0.00026 19.9 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EWM29526.1 - 0.00013 21.2 2.1 0.00015 20.9 0.9 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EWM29526.1 - 0.00032 19.6 0.8 0.0014 17.5 0.3 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 EWM29526.1 - 0.00073 18.1 0.2 0.0011 17.4 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EWM29526.1 - 0.00099 18.0 0.9 0.0017 17.3 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EWM29526.1 - 0.018 15.0 0.7 0.018 15.0 0.5 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EWM29526.1 - 0.032 13.1 0.2 0.071 12.0 0.1 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein XdhC_C PF13478.1 EWM29526.1 - 0.085 13.1 0.0 7.3 6.9 0.0 2.5 2 0 0 2 2 2 0 XdhC Rossmann domain SNF2_N PF00176.18 EWM29527.1 - 6e-53 179.5 0.0 8.6e-53 179.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EWM29527.1 - 1.3e-09 37.7 0.0 2.7e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EWM29527.1 - 1.3e-07 31.6 0.0 2.7e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EWM29527.1 - 5.6e-06 25.9 0.0 1.1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 EWM29527.1 - 0.0024 16.7 0.0 0.02 13.7 0.0 2.1 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.1 EWM29527.1 - 0.027 14.6 0.0 0.076 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF2663 PF10864.3 EWM29530.1 - 0.057 13.6 0.1 0.071 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) DUF2614 PF11023.3 EWM29530.1 - 0.62 9.8 3.0 0.8 9.4 1.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) DUF4345 PF14248.1 EWM29530.1 - 0.85 9.0 4.9 9.9 5.6 0.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4345) DUF1469 PF07332.6 EWM29530.1 - 4.8 6.9 9.8 0.38 10.4 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1469) Lactamase_B_2 PF12706.2 EWM29531.1 - 1.5e-32 112.7 0.0 1.9e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EWM29531.1 - 0.00025 20.7 0.1 0.058 13.0 0.0 2.4 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily DUF4082 PF13313.1 EWM29532.1 - 4.1e-19 68.4 0.1 3.6e-18 65.4 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4082) DUF4602 PF15375.1 EWM29533.1 - 1.4e-18 67.2 1.1 2.3e-18 66.5 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4602) UNC-50 PF05216.8 EWM29534.1 - 3e-71 239.3 9.0 3.5e-71 239.0 6.2 1.0 1 0 0 1 1 1 1 UNC-50 family MRP PF09387.5 EWM29534.1 - 0.028 14.1 0.2 0.12 12.1 0.1 1.8 2 0 0 2 2 2 0 Mitochondrial RNA binding protein MRP Condensation PF00668.15 EWM29535.1 - 5.4e-13 48.4 0.0 1.1e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Condensation domain AATase PF07247.7 EWM29535.1 - 4e-08 32.2 0.0 4.6e-06 25.4 0.0 3.3 2 1 0 2 2 2 1 Alcohol acetyltransferase DAGAT PF03982.8 EWM29536.1 - 6e-33 113.8 0.0 9.5e-33 113.1 0.0 1.3 1 1 0 1 1 1 1 Diacylglycerol acyltransferase Not3 PF04065.10 EWM29537.1 - 3.8e-74 248.8 28.5 3.8e-74 248.8 19.8 3.1 3 0 0 3 3 3 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EWM29537.1 - 9.4e-45 151.7 7.1 9.4e-45 151.7 4.9 4.5 4 2 0 4 4 4 1 NOT2 / NOT3 / NOT5 family DNA_photolyase PF00875.13 EWM29541.1 - 7.6e-27 94.0 0.0 1.3e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase FAD_binding_7 PF03441.9 EWM29541.1 - 2.2e-15 56.6 0.0 3.1e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DUF1904 PF08921.6 EWM29541.1 - 0.062 13.3 0.0 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1904) Mpv17_PMP22 PF04117.7 EWM29542.1 - 2.5e-10 39.8 0.3 7.6e-10 38.2 0.0 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family AA_kinase PF00696.23 EWM29543.1 - 4.2e-31 108.3 0.1 1e-30 107.0 0.1 1.7 1 0 0 1 1 1 1 Amino acid kinase family Aldedh PF00171.17 EWM29543.1 - 3e-14 52.2 0.7 8.1e-11 40.9 0.3 3.0 4 0 0 4 4 4 2 Aldehyde dehydrogenase family Biotin_lipoyl PF00364.17 EWM29544.1 - 4.4e-14 51.8 0.0 6.9e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme FimH_man-bind PF09160.5 EWM29544.1 - 0.092 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 FimH, mannose binding TraB PF01963.12 EWM29545.1 - 0.013 14.9 0.1 0.59 9.5 0.0 2.1 2 0 0 2 2 2 0 TraB family Myb_DNA-binding PF00249.26 EWM29546.1 - 0.011 15.7 0.8 0.016 15.2 0.0 1.7 2 0 0 2 2 2 0 Myb-like DNA-binding domain RAP1 PF07218.6 EWM29546.1 - 4.3 5.3 7.5 5 5.0 5.2 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pkinase PF00069.20 EWM29547.1 - 1.4e-64 217.8 0.0 1.9e-64 217.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM29547.1 - 3.5e-45 154.1 0.0 5.2e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EWM29547.1 - 3e-06 26.3 0.0 0.00015 20.8 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EWM29547.1 - 0.00084 19.1 0.4 0.47 10.1 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EWM29547.1 - 0.0021 17.1 0.0 0.0043 16.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Sugar_tr PF00083.19 EWM29548.1 - 5.1e-34 117.6 26.5 3.7e-32 111.5 18.3 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EWM29548.1 - 4.8e-26 91.2 43.0 2e-24 85.9 17.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EWM29548.1 - 2.9e-07 29.2 16.5 0.0037 15.7 4.6 3.1 1 1 2 3 3 3 3 MFS/sugar transport protein BT1 PF03092.11 EWM29548.1 - 0.00063 18.5 0.2 0.0018 17.0 0.1 1.8 2 0 0 2 2 2 1 BT1 family DUF336 PF03928.9 EWM29549.1 - 6.9e-28 97.0 0.5 8.1e-28 96.8 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF336) DUF1937 PF09152.5 EWM29549.1 - 0.037 14.6 0.1 0.053 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1937) DUF1772 PF08592.6 EWM29549.1 - 0.098 12.3 0.6 12 5.6 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) NUDIX PF00293.23 EWM29552.1 - 7.2e-14 51.5 0.1 1.9e-13 50.2 0.1 1.7 1 0 0 1 1 1 1 NUDIX domain AAA_28 PF13521.1 EWM29553.1 - 3.1e-21 76.0 0.0 4.1e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain DAP3 PF10236.4 EWM29553.1 - 0.00068 18.6 0.0 0.001 18.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_30 PF13604.1 EWM29553.1 - 0.0033 17.0 0.0 0.0062 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EWM29553.1 - 0.0044 16.7 0.1 0.013 15.2 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain KTI12 PF08433.5 EWM29553.1 - 0.016 14.4 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 LRR_4 PF12799.2 EWM29554.1 - 1.3e-26 91.6 18.0 9.9e-07 28.2 1.7 6.3 3 1 5 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EWM29554.1 - 1.8e-24 85.2 35.0 1.8e-08 33.9 0.3 4.9 2 1 4 6 6 6 5 Leucine rich repeat LRR_1 PF00560.28 EWM29554.1 - 1.1e-22 76.5 12.4 0.075 13.1 0.1 9.6 9 1 0 9 9 9 7 Leucine Rich Repeat LRR_6 PF13516.1 EWM29554.1 - 1.7e-13 49.0 6.5 1.6 9.0 0.0 8.9 7 2 2 9 9 9 5 Leucine Rich repeat LRR_7 PF13504.1 EWM29554.1 - 2.7e-11 41.7 19.5 1.7 9.1 0.0 9.8 9 1 1 10 10 10 3 Leucine rich repeat Pox_A31 PF05771.6 EWM29555.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.3 1 1 0 1 1 1 0 Poxvirus A31 protein p450 PF00067.17 EWM29556.1 - 4.2e-77 259.6 0.0 6.1e-77 259.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 NYN PF01936.13 EWM29557.1 - 0.0074 16.5 0.3 0.046 13.9 0.0 2.3 3 0 0 3 3 3 1 NYN domain ECH PF00378.15 EWM29558.1 - 4.3e-35 120.9 0.0 5.1e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_C50 PF03568.12 EWM29559.1 - 2.8e-32 111.8 0.0 4.5e-20 71.6 0.0 2.1 2 0 0 2 2 2 2 Peptidase family C50 CHAT PF12770.2 EWM29559.1 - 4.5e-06 26.0 0.0 0.00021 20.5 0.0 2.4 1 1 0 1 1 1 1 CHAT domain Pantoate_transf PF02548.10 EWM29560.1 - 6.3e-106 353.2 1.0 8.5e-106 352.8 0.7 1.2 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 EWM29560.1 - 7.2e-06 25.3 1.1 2.9e-05 23.4 0.8 1.9 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Glutaredoxin PF00462.19 EWM29561.1 - 1.6e-17 63.2 0.0 2.8e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 EWM29561.1 - 0.0081 16.3 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Kinesin PF00225.18 EWM29562.1 - 2.4e-24 85.6 0.0 2.8e-19 69.0 0.0 3.1 4 0 0 4 4 4 2 Kinesin motor domain PPR_2 PF13041.1 EWM29563.1 - 9.3e-58 192.0 0.4 2.2e-11 43.5 0.0 13.9 7 3 8 15 15 15 12 PPR repeat family PPR_3 PF13812.1 EWM29563.1 - 5.5e-44 144.7 15.0 3.8e-05 23.6 0.0 15.5 15 1 0 15 15 15 10 Pentatricopeptide repeat domain PPR_1 PF12854.2 EWM29563.1 - 2.5e-41 138.8 4.1 5.8e-08 32.0 0.0 13.4 15 0 0 15 15 15 7 PPR repeat PPR PF01535.15 EWM29563.1 - 1.4e-34 115.6 15.2 8.7e-05 22.2 0.0 13.7 15 0 0 15 15 15 8 PPR repeat ECSIT PF06239.6 EWM29563.1 - 1.6e-06 27.1 0.0 1.4 7.7 0.0 4.3 3 1 1 4 4 4 3 Evolutionarily conserved signalling intermediate in Toll pathway TPR_14 PF13428.1 EWM29563.1 - 9.3e-06 25.8 12.4 1.5 9.6 0.2 7.5 8 1 0 8 8 6 1 Tetratricopeptide repeat BTAD PF03704.12 EWM29563.1 - 0.00018 21.8 6.7 3 8.1 0.1 5.2 4 1 1 5 5 5 2 Bacterial transcriptional activator domain TPR_7 PF13176.1 EWM29563.1 - 0.0029 17.2 0.6 3.3 7.7 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EWM29563.1 - 0.003 18.1 6.7 38 5.1 0.0 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat MRP-S27 PF10037.4 EWM29563.1 - 0.2 10.5 0.0 0.49 9.2 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 TPR_2 PF07719.12 EWM29563.1 - 1.7 8.7 5.4 18 5.5 0.1 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 EWM29563.1 - 8.1 7.1 13.5 6.5 7.4 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat SNase PF00565.12 EWM29564.1 - 4.6e-20 71.8 0.0 8.2e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Staphylococcal nuclease homologue ORC2 PF04084.9 EWM29565.1 - 3.6e-50 170.6 0.0 1.6e-49 168.5 0.0 1.8 1 1 0 1 1 1 1 Origin recognition complex subunit 2 Bromodomain PF00439.20 EWM29567.1 - 3.6e-10 39.6 0.0 7.4e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Bromodomain FYRN PF05964.9 EWM29567.1 - 0.00017 21.0 0.0 0.00038 19.8 0.0 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus PHD PF00628.24 EWM29567.1 - 0.00023 20.7 5.4 0.0007 19.2 3.7 1.9 1 0 0 1 1 1 1 PHD-finger Choline_transpo PF04515.7 EWM29568.1 - 2.3e-54 184.3 15.2 2.3e-54 184.3 10.6 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter Ndc1_Nup PF09531.5 EWM29568.1 - 0.02 13.3 0.8 0.043 12.2 0.6 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Borrelia_P13 PF05628.7 EWM29568.1 - 0.4 10.4 3.0 1.3 8.8 2.1 1.8 1 0 0 1 1 1 0 Borrelia membrane protein P13 PDDEXK_1 PF12705.2 EWM29569.1 - 1.5e-37 129.3 0.0 1.8e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.12 EWM29569.1 - 2.4e-05 24.3 0.0 0.0011 18.8 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function DUF83 DUF2800 PF10926.3 EWM29569.1 - 0.0033 16.6 0.0 0.013 14.6 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2800) Dna2 PF08696.6 EWM29569.1 - 0.0058 15.9 0.0 0.0089 15.3 0.0 1.2 1 0 0 1 1 1 1 DNA replication factor Dna2 DUF2587 PF10759.4 EWM29569.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) PDDEXK_1 PF12705.2 EWM29570.1 - 2.1e-27 96.1 0.0 2.5e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Dna2 PF08696.6 EWM29570.1 - 0.0063 15.8 0.0 0.0096 15.2 0.0 1.2 1 0 0 1 1 1 1 DNA replication factor Dna2 DUF2587 PF10759.4 EWM29570.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) OTU PF02338.14 EWM29571.1 - 2.5e-10 40.9 0.0 7.3e-10 39.4 0.0 1.8 2 0 0 2 2 2 1 OTU-like cysteine protease CaMKII_AD PF08332.5 EWM29571.1 - 1.1e-09 38.3 0.0 2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II Association DUF4440 PF14534.1 EWM29571.1 - 1.4e-08 34.9 0.1 2.9e-08 33.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.1 EWM29571.1 - 2.7e-07 30.6 0.0 1.2e-06 28.5 0.0 2.0 2 0 0 2 2 2 1 SnoaL-like domain Peptidase_C65 PF10275.4 EWM29571.1 - 0.17 11.2 0.0 0.81 8.9 0.0 2.1 2 1 1 3 3 3 0 Peptidase C65 Otubain DUF423 PF04241.10 EWM29572.1 - 0.099 12.5 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF423) Cys_rich_FGFR PF00839.12 EWM29574.1 - 0.084 12.8 0.4 0.11 12.4 0.2 1.5 1 1 0 1 1 1 0 Cysteine rich repeat MatE PF01554.13 EWM29576.1 - 1.5e-27 96.2 33.3 5.7e-16 58.5 5.1 3.0 3 1 0 3 3 3 2 MatE PolyA_pol PF01743.15 EWM29577.1 - 2.3e-24 86.0 0.0 6.1e-24 84.6 0.0 1.7 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EWM29577.1 - 0.0071 15.8 0.0 0.02 14.4 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A F-box-like PF12937.2 EWM29578.1 - 0.00021 20.9 0.4 0.00062 19.4 0.3 1.8 1 0 0 1 1 1 1 F-box-like zf-CCCH PF00642.19 EWM29578.1 - 0.019 14.6 1.4 0.061 13.0 1.0 1.9 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MMR_HSR1 PF01926.18 EWM29579.1 - 4.1e-12 46.0 0.0 8.9e-11 41.7 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EWM29579.1 - 8.8e-06 24.9 0.0 1.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EWM29579.1 - 0.0027 17.0 0.0 0.013 14.7 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B HAD PF12710.2 EWM29580.1 - 5.1e-17 62.6 0.0 1.8e-16 60.9 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EWM29580.1 - 1e-14 55.4 0.1 2.4e-07 31.3 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EWM29580.1 - 8.3e-14 51.1 0.0 1.9e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EWM29580.1 - 5.3e-11 42.3 0.0 1.6e-10 40.8 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EWM29580.1 - 0.0015 18.2 0.0 0.0056 16.2 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Sld5 PF05916.6 EWM29582.1 - 1.2e-05 25.5 0.0 1.6e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Helicase_C_2 PF13307.1 EWM29583.1 - 1e-51 175.2 0.0 2.2e-51 174.1 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 EWM29583.1 - 1.1e-44 151.9 0.0 1.7e-44 151.2 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 zf-C3HC4_2 PF13923.1 EWM29583.1 - 7e-05 22.7 8.9 0.00019 21.3 6.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 EWM29583.1 - 0.00054 19.5 0.0 0.43 10.0 0.0 2.9 3 0 0 3 3 3 2 DEAD/DEAH box helicase zf-C3HC4 PF00097.20 EWM29583.1 - 0.00073 19.1 3.8 0.0019 17.7 2.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 EWM29583.1 - 0.00076 19.3 0.0 0.15 11.8 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EWM29583.1 - 0.018 13.8 0.0 0.12 11.1 0.0 2.0 1 1 0 1 1 1 0 SNF2 family N-terminal domain zf-RING_2 PF13639.1 EWM29583.1 - 0.023 14.5 7.1 0.065 13.0 4.9 1.8 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.1 EWM29583.1 - 0.28 10.9 5.7 0.67 9.7 3.9 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.1 EWM29583.1 - 0.89 9.3 8.0 6.2 6.6 5.4 2.3 1 1 1 2 2 2 0 zinc-RING finger domain Beta-lactamase PF00144.19 EWM29584.1 - 3.8e-22 78.7 0.1 9.5e-22 77.4 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase Band_7 PF01145.20 EWM29585.1 - 3.3e-29 102.0 0.0 6.8e-29 101.0 0.0 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EWM29585.1 - 0.0057 16.1 0.0 0.0096 15.4 0.0 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family RF-1 PF00472.15 EWM29586.1 - 2.7e-40 136.7 0.9 5.6e-40 135.7 0.6 1.6 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 EWM29586.1 - 1.5e-33 114.9 0.0 4.7e-33 113.3 0.0 1.9 1 0 0 1 1 1 1 PCRF domain Queuosine_synth PF02547.10 EWM29587.1 - 3e-94 315.5 0.0 1.5e-69 234.3 0.0 2.0 2 0 0 2 2 2 2 Queuosine biosynthesis protein Rsm22 PF09243.5 EWM29591.1 - 1.3e-42 145.7 0.0 6.8e-42 143.3 0.0 1.9 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_18 PF12847.2 EWM29591.1 - 1e-08 35.7 0.0 2e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM29591.1 - 5.2e-05 23.0 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM29591.1 - 0.0007 19.9 0.0 0.0013 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM29591.1 - 0.0048 17.3 0.0 0.01 16.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM29591.1 - 0.048 14.1 0.0 0.098 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RGS PF00615.14 EWM29592.1 - 9.7e-18 64.3 0.0 8.5e-15 54.8 0.0 3.3 3 0 0 3 3 3 2 Regulator of G protein signaling domain DENN PF02141.16 EWM29592.1 - 1.5e-10 41.1 2.2 1.8e-10 40.8 0.3 2.0 2 0 0 2 2 2 1 DENN (AEX-3) domain dDENN PF03455.14 EWM29592.1 - 4.8e-09 36.1 2.4 1e-08 35.1 1.6 1.6 1 0 0 1 1 1 1 dDENN domain Bin3 PF06859.7 EWM29593.1 - 1.1e-30 105.8 0.0 1.9e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_18 PF12847.2 EWM29593.1 - 2.9e-11 43.9 0.1 3e-10 40.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM29593.1 - 2.5e-10 40.3 1.2 4.8e-10 39.3 0.8 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM29593.1 - 4e-09 36.8 0.0 0.00082 19.8 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 EWM29593.1 - 5.8e-09 36.3 0.0 0.0041 17.5 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 EWM29593.1 - 4.7e-07 29.5 0.0 0.00021 20.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 EWM29593.1 - 9.2e-06 25.9 0.0 0.013 15.8 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 EWM29593.1 - 0.0026 17.7 0.0 0.016 15.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EWM29593.1 - 0.047 12.7 0.0 0.23 10.5 0.0 1.9 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family MTS PF05175.9 EWM29593.1 - 0.17 11.2 0.0 4.5 6.6 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain DUF2637 PF10935.3 EWM29594.1 - 1.6 8.6 6.4 0.13 12.2 1.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2637) DUF1517 PF07466.6 EWM29594.1 - 4.7 6.1 8.2 0.094 11.6 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) CMAS PF02353.15 EWM29595.1 - 1.3e-27 96.5 0.0 1.2e-19 70.4 0.0 2.2 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Amino_oxidase PF01593.19 EWM29595.1 - 1.3e-12 47.5 0.1 1.5e-10 40.7 0.0 2.5 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EWM29595.1 - 3.6e-11 42.9 0.1 7.6e-11 41.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Methyltransf_18 PF12847.2 EWM29595.1 - 3e-05 24.5 0.0 7.9e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_9 PF13454.1 EWM29595.1 - 8.3e-05 22.4 1.1 0.00098 18.9 0.1 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 EWM29595.1 - 0.00012 21.0 1.6 0.001 18.0 0.0 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase DOT1 PF08123.8 EWM29595.1 - 0.00053 19.3 0.0 0.00097 18.5 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Pyr_redox_3 PF13738.1 EWM29595.1 - 0.00055 20.0 0.2 0.0096 15.9 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_11 PF08241.7 EWM29595.1 - 0.019 15.4 0.0 0.075 13.5 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain Pyr_redox_2 PF07992.9 EWM29595.1 - 0.02 14.7 0.1 0.053 13.3 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_23 PF13489.1 EWM29595.1 - 0.021 14.5 0.0 0.058 13.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EWM29595.1 - 0.04 13.5 0.0 0.082 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EWM29595.1 - 0.074 13.0 0.5 0.4 10.7 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain K_oxygenase PF13434.1 EWM29595.1 - 0.085 11.7 0.2 1.2 7.9 0.0 2.3 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 EWM29595.1 - 0.16 11.5 0.4 0.55 9.7 0.1 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N PF00107.21 EWM29595.1 - 0.17 11.4 0.9 0.74 9.3 0.3 2.1 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Gal-3-0_sulfotr PF06990.6 EWM29597.1 - 7.2e-08 31.4 0.3 0.0022 16.6 0.2 2.1 1 1 1 2 2 2 2 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.9 EWM29597.1 - 7.6e-05 22.5 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family DUF4490 PF14892.1 EWM29598.1 - 3.2e-10 39.6 1.3 3.8e-10 39.3 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) GPI2 PF06432.6 EWM29599.1 - 3.8e-66 223.3 4.5 5.9e-35 120.9 0.2 1.9 2 0 0 2 2 2 2 Phosphatidylinositol N-acetylglucosaminyltransferase HECT PF00632.20 EWM29600.1 - 4.1e-88 295.5 0.0 5.6e-88 295.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Hydrolase_6 PF13344.1 EWM29601.1 - 1.5e-30 105.0 0.0 2.8e-30 104.1 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EWM29601.1 - 3.3e-18 65.1 0.0 8.2e-18 63.8 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EWM29601.1 - 2.8e-09 37.6 0.1 1e-08 35.9 0.0 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EWM29601.1 - 7.8e-07 29.4 0.5 0.017 15.3 0.0 2.8 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 EWM29601.1 - 0.0068 15.7 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Gtr1_RagA PF04670.7 EWM29602.1 - 2.6e-94 314.7 0.3 3.6e-94 314.2 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EWM29602.1 - 2.2e-09 36.7 0.0 5.5e-09 35.5 0.0 1.7 1 1 1 2 2 2 1 ADP-ribosylation factor family Ras PF00071.17 EWM29602.1 - 5.4e-09 35.6 0.1 1.1e-08 34.5 0.0 1.6 2 0 0 2 2 2 1 Ras family Miro PF08477.8 EWM29602.1 - 1.9e-07 31.5 0.1 6.6e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EWM29602.1 - 0.0035 17.2 0.0 0.0068 16.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EWM29602.1 - 0.022 14.2 0.2 0.065 12.7 0.1 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 EWM29602.1 - 0.073 13.0 0.0 0.19 11.6 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EWM29602.1 - 0.076 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 EWM29602.1 - 0.11 11.9 1.2 0.25 10.9 0.8 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Leu_leader PF08054.6 EWM29602.1 - 0.18 11.4 3.1 0.4 10.3 2.2 1.5 1 0 0 1 1 1 0 Leucine operon leader peptide HSP90 PF00183.13 EWM29604.1 - 2.1e-257 854.7 28.5 2.5e-257 854.5 19.8 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 EWM29604.1 - 1.3e-12 47.3 0.0 3.2e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EWM29604.1 - 2.9e-11 43.1 0.2 2.9e-11 43.1 0.1 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1510 PF07423.6 EWM29604.1 - 1.6 8.0 20.6 0.12 11.7 10.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) YqfQ PF14181.1 EWM29604.1 - 5.8 6.9 13.3 18 5.3 9.2 1.8 1 0 0 1 1 1 0 YqfQ-like protein Exo_endo_phos PF03372.18 EWM29605.1 - 1e-06 28.8 2.6 5.7e-06 26.4 0.0 2.5 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Sod_Fe_N PF00081.17 EWM29605.1 - 0.096 12.9 0.5 0.24 11.6 0.4 1.6 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain SpoU_methylase PF00588.14 EWM29606.1 - 3.8e-27 94.9 0.0 5.7e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family CRAL_TRIO PF00650.15 EWM29608.1 - 1.5e-21 76.5 0.0 2.3e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EWM29608.1 - 1.9e-09 37.6 0.0 3.2e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain TPT PF03151.11 EWM29609.1 - 3.3e-25 88.5 1.5 3.3e-25 88.5 1.1 2.5 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EWM29609.1 - 2.6e-09 37.1 24.1 3.3e-06 27.1 1.7 2.9 2 1 2 4 4 4 2 EamA-like transporter family UAA PF08449.6 EWM29609.1 - 8.6e-07 28.1 0.9 8.6e-07 28.1 0.6 2.7 2 1 0 2 2 2 1 UAA transporter family Ribosomal_L34e PF01199.13 EWM29610.1 - 2e-36 124.0 6.6 2.6e-36 123.7 4.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e Spermine_synth PF01564.12 EWM29611.1 - 5.4e-88 294.0 0.0 7.3e-88 293.6 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 EWM29611.1 - 3.1e-05 24.5 0.0 7.1e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM29611.1 - 0.008 16.6 0.0 0.029 14.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_30 PF05430.6 EWM29611.1 - 0.0092 15.6 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_26 PF13659.1 EWM29611.1 - 0.01 15.8 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.1 EWM29611.1 - 0.052 14.3 0.0 0.17 12.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 EWM29611.1 - 0.11 12.2 0.0 0.74 9.5 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EWM29611.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain zf-C3HC4_3 PF13920.1 EWM29613.1 - 2.9e-09 36.4 9.4 9.1e-09 34.8 6.5 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) HATPase_c_3 PF13589.1 EWM29613.1 - 0.00015 21.4 0.2 0.051 13.2 0.0 3.6 2 2 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UBA PF00627.26 EWM29613.1 - 0.0037 17.0 0.0 0.017 14.9 0.0 2.3 1 0 0 1 1 1 1 UBA/TS-N domain zf-RING_5 PF14634.1 EWM29613.1 - 0.046 13.4 12.1 0.14 11.9 8.4 1.9 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EWM29613.1 - 0.061 13.3 15.5 0.039 13.9 8.8 2.4 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EWM29613.1 - 0.26 10.9 13.6 0.3 10.7 8.2 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 EWM29613.1 - 0.28 10.7 6.7 0.68 9.5 4.6 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 COG7 PF10191.4 EWM29613.1 - 1.7 6.4 0.5 3.5 5.4 0.3 1.4 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) DUF2039 PF10217.4 EWM29613.1 - 4.4 7.3 5.0 9.4 6.3 3.5 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) SURF4 PF02077.10 EWM29613.1 - 7.6 5.8 0.0 13 5.0 0.0 1.3 1 0 0 1 1 1 0 SURF4 family DUF3684 PF12449.3 EWM29613.1 - 9.2 3.6 0.0 22 2.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3684) SR-25 PF10500.4 EWM29614.1 - 0.0088 15.5 5.5 0.0088 15.5 3.8 2.5 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein DENN PF02141.16 EWM29615.1 - 5.2e-37 127.3 0.3 1.2e-36 126.1 0.2 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 EWM29615.1 - 1.5e-14 53.8 0.1 3.5e-14 52.6 0.1 1.7 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.13 EWM29615.1 - 2.4e-09 37.0 0.0 5.4e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 uDENN domain DUF2464 PF10240.4 EWM29615.1 - 3.4e-08 33.1 0.2 8.4e-08 31.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2464) PPR_2 PF13041.1 EWM29615.1 - 0.002 18.0 0.0 0.083 12.8 0.0 2.6 1 1 1 2 2 2 1 PPR repeat family PPR_3 PF13812.1 EWM29615.1 - 0.059 13.6 0.2 0.66 10.4 0.0 2.8 2 0 0 2 2 2 0 Pentatricopeptide repeat domain Tic20 PF09685.5 EWM29616.1 - 0.54 10.2 8.2 0.1 12.6 1.3 2.6 2 1 0 2 2 2 0 Tic20-like protein Bestrophin PF01062.16 EWM29617.1 - 2.9e-52 177.4 1.2 2.9e-52 177.4 0.9 1.5 2 0 0 2 2 2 1 Bestrophin, RFP-TM, chloride channel RNA_pol_Rpb1_5 PF04998.12 EWM29618.1 - 3.7e-88 295.3 0.0 6e-88 294.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EWM29618.1 - 1.2e-81 274.5 0.0 2.1e-81 273.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EWM29618.1 - 8.6e-71 237.2 0.0 1.6e-70 236.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EWM29618.1 - 1.9e-48 164.2 0.0 4.3e-48 163.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_6 PF04992.9 EWM29618.1 - 3.8e-48 163.7 0.1 6e-48 163.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_4 PF05000.12 EWM29618.1 - 2.9e-34 117.0 0.0 5.5e-34 116.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_7 PF04990.7 EWM29618.1 - 3.2e-26 91.6 0.3 6.8e-26 90.5 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_R PF05001.8 EWM29618.1 - 0.00096 19.0 207.2 0.034 14.2 6.3 13.4 3 2 11 16 16 16 15 RNA polymerase Rpb1 C-terminal repeat Peptidase_C48 PF02902.14 EWM29619.1 - 5.1e-08 32.7 0.0 8.7e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Histone PF00125.19 EWM29620.1 - 2.3e-13 50.0 0.1 2.9e-13 49.7 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EWM29620.1 - 0.00012 22.1 0.1 0.00018 21.6 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EWM29620.1 - 0.0011 18.8 0.1 0.0015 18.3 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EWM29620.1 - 0.0044 17.0 0.0 0.0071 16.3 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EWM29620.1 - 0.092 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.10 EWM29620.1 - 0.095 12.4 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CENP-T PF15511.1 EWM29620.1 - 0.13 11.4 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF221 PF02714.10 EWM29621.1 - 1.2e-61 208.3 19.7 1.8e-61 207.8 13.7 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EWM29621.1 - 6.4e-32 110.2 0.6 6.4e-32 110.2 0.4 2.1 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EWM29621.1 - 0.0026 18.2 0.0 0.0062 17.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Ribosomal_S21e PF01249.13 EWM29622.1 - 2.2e-33 114.0 0.3 2.4e-33 113.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Pyr_redox_2 PF07992.9 EWM29624.1 - 8.4e-40 136.7 0.0 1.5e-39 135.9 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EWM29624.1 - 6e-38 129.2 2.3 4.2e-37 126.5 0.1 2.6 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EWM29624.1 - 3.3e-24 85.0 9.0 4.5e-22 78.2 0.1 4.3 4 1 1 5 5 4 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EWM29624.1 - 1.1e-08 34.6 4.2 3.5e-08 32.9 2.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EWM29624.1 - 2.1e-07 31.1 0.2 0.0006 19.9 0.1 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EWM29624.1 - 4.2e-07 29.1 5.6 5.9e-06 25.3 2.4 2.4 2 1 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EWM29624.1 - 3.6e-06 26.9 2.4 0.013 15.5 0.3 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EWM29624.1 - 0.00043 19.2 3.7 0.00043 19.2 2.6 2.8 3 1 0 3 3 3 1 FAD binding domain Thi4 PF01946.12 EWM29624.1 - 0.00045 19.3 2.8 0.0022 17.1 0.2 2.3 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.1 EWM29624.1 - 0.0041 16.0 0.2 0.064 12.1 0.0 2.5 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EWM29624.1 - 0.015 13.8 11.0 0.23 9.8 1.5 3.7 2 1 2 4 4 4 0 HI0933-like protein AlaDh_PNT_C PF01262.16 EWM29624.1 - 0.051 13.1 0.1 0.051 13.1 0.1 2.4 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.19 EWM29624.1 - 0.062 12.1 9.2 2 7.2 0.3 3.4 3 0 0 3 3 3 0 FAD dependent oxidoreductase UPF0150 PF03681.10 EWM29624.1 - 0.07 12.7 0.1 0.27 10.8 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0150) FAD_binding_3 PF01494.14 EWM29624.1 - 0.11 11.4 10.8 4.1 6.3 1.0 3.5 2 1 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.13 EWM29624.1 - 0.14 11.8 0.1 0.14 11.8 0.1 1.8 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1415 PF07209.7 EWM29625.1 - 6.1e-37 127.0 0.0 8.7e-37 126.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1415) adh_short PF00106.20 EWM29626.1 - 1.2e-35 122.9 0.5 1.4e-35 122.6 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EWM29626.1 - 1.3e-27 97.1 0.1 1.5e-27 96.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EWM29626.1 - 5.9e-15 55.3 0.5 7.8e-15 54.9 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EWM29626.1 - 0.00017 21.0 0.1 0.00034 20.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EWM29626.1 - 0.0032 16.4 0.1 0.015 14.2 0.1 1.9 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EWM29626.1 - 0.053 13.5 0.1 0.071 13.1 0.1 1.3 1 1 0 1 1 1 0 NADH(P)-binding HAD_2 PF13419.1 EWM29627.1 - 4.3e-27 95.4 0.1 3.3e-26 92.5 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase NIF PF03031.13 EWM29627.1 - 7e-05 22.5 0.0 0.00047 19.8 0.0 2.0 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase PF00702.21 EWM29627.1 - 0.00063 20.2 0.0 0.12 12.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EWM29627.1 - 0.0088 15.7 0.0 0.061 13.0 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.2 EWM29627.1 - 0.13 12.3 0.0 0.14 12.3 0.0 1.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Linker_histone PF00538.14 EWM29629.1 - 1.2e-13 50.9 2.2 1.4e-13 50.7 0.1 2.2 2 0 0 2 2 2 1 linker histone H1 and H5 family Str_synth PF03088.11 EWM29629.1 - 0.0048 16.8 0.0 0.0093 15.9 0.0 1.4 1 0 0 1 1 1 1 Strictosidine synthase Phytochelatin PF05023.9 EWM29630.1 - 7.4e-77 257.1 0.0 3e-40 137.4 0.0 2.2 2 0 0 2 2 2 2 Phytochelatin synthase Acetyltransf_1 PF00583.19 EWM29631.1 - 3.2e-09 36.7 1.7 1.5e-08 34.5 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EWM29631.1 - 0.00016 21.3 0.0 0.00042 20.0 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EWM29631.1 - 0.00019 21.5 0.7 0.0004 20.4 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EWM29631.1 - 0.013 15.6 0.1 0.031 14.4 0.1 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pyr_redox_2 PF07992.9 EWM29632.1 - 1.9e-20 73.6 0.0 2.7e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EWM29632.1 - 1.1e-05 25.7 0.1 0.00015 22.0 0.0 2.8 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EWM29632.1 - 0.15 12.0 0.0 0.45 10.5 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MIF4G PF02854.14 EWM29633.1 - 1.3e-17 63.9 0.0 3e-16 59.4 0.0 2.5 3 0 0 3 3 3 1 MIF4G domain MA3 PF02847.12 EWM29633.1 - 1.3e-17 63.4 0.3 9.9e-17 60.6 0.0 2.6 3 1 0 3 3 3 1 MA3 domain Spore_coat_CotO PF14153.1 EWM29633.1 - 0.028 13.8 7.6 0.052 12.9 5.3 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Daxx PF03344.10 EWM29633.1 - 0.48 8.8 26.3 0.98 7.8 18.2 1.4 1 0 0 1 1 1 0 Daxx Family Prog_receptor PF02161.10 EWM29633.1 - 0.67 8.7 10.1 0.99 8.1 7.0 1.2 1 0 0 1 1 1 0 Progesterone receptor Nop14 PF04147.7 EWM29633.1 - 6.3 4.5 29.0 9.7 3.9 20.1 1.2 1 0 0 1 1 1 0 Nop14-like family Methyltransf_6 PF03737.10 EWM29634.1 - 3.1e-51 173.2 0.1 3.9e-51 172.9 0.0 1.1 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase Cyt-b5 PF00173.23 EWM29635.1 - 7.8e-21 73.6 0.1 4.5e-11 42.3 0.1 2.4 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Exo_endo_phos PF03372.18 EWM29636.1 - 6.2e-24 85.2 0.0 1e-23 84.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EWM29636.1 - 0.16 11.5 0.0 0.36 10.4 0.0 1.6 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase ATP-synt_F PF01990.12 EWM29637.1 - 3.1e-32 110.8 0.1 3.6e-32 110.5 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DXP_synthase_N PF13292.1 EWM29637.1 - 0.02 13.8 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase DHQS PF01959.11 EWM29638.1 - 1.2e-74 251.1 3.4 1.1e-71 241.4 2.3 2.0 1 1 0 1 1 1 1 3-dehydroquinate synthase (EC 4.6.1.3) Hint PF01079.15 EWM29638.1 - 0.034 13.3 0.1 0.12 11.5 0.0 1.8 2 0 0 2 2 2 0 Hint module DUF3389 PF11869.3 EWM29638.1 - 0.039 13.8 0.2 0.089 12.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3389) Phage_sheath_1 PF04984.9 EWM29638.1 - 0.083 11.3 0.2 0.12 10.8 0.1 1.2 1 0 0 1 1 1 0 Phage tail sheath protein Hom_end_hint PF05203.11 EWM29638.1 - 0.097 12.3 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint DUF1042 PF06294.6 EWM29639.1 - 2e-30 105.4 0.0 3.9e-30 104.5 0.0 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1042) CAMSAP_CH PF11971.3 EWM29639.1 - 5.6e-14 51.5 0.0 9e-14 50.8 0.0 1.3 1 0 0 1 1 1 1 CAMSAP CH domain ATG16 PF08614.6 EWM29639.1 - 8.7e-05 22.4 0.3 0.00014 21.7 0.0 1.5 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) CH PF00307.26 EWM29639.1 - 0.014 15.3 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Calponin homology (CH) domain Tcp11 PF05794.8 EWM29640.1 - 1e-25 90.3 0.0 1.7e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 T-complex protein 11 Pescadillo_N PF06732.6 EWM29641.1 - 6.6e-103 343.8 0.1 9.1e-103 343.3 0.1 1.1 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT PF00533.21 EWM29641.1 - 0.00068 19.7 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Nop14 PF04147.7 EWM29641.1 - 0.36 8.6 3.8 0.59 7.9 2.6 1.2 1 0 0 1 1 1 0 Nop14-like family RPE65 PF03055.10 EWM29642.1 - 5.7e-73 246.1 0.0 2.2e-72 244.1 0.0 1.9 1 1 0 1 1 1 1 Retinal pigment epithelial membrane protein TspO_MBR PF03073.10 EWM29643.1 - 1.2e-24 86.4 14.9 2.5e-24 85.4 10.3 1.5 1 0 0 1 1 1 1 TspO/MBR family DUF2413 PF10310.4 EWM29643.1 - 0.012 14.4 8.0 0.016 14.0 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Gag_spuma PF03276.9 EWM29643.1 - 0.78 7.9 5.6 1.1 7.5 3.9 1.1 1 0 0 1 1 1 0 Spumavirus gag protein G0-G1_switch_2 PF15103.1 EWM29643.1 - 1.1 9.4 4.6 4.6 7.5 3.2 1.9 1 1 0 1 1 1 0 G0/G1 switch protein 2 Histone PF00125.19 EWM29644.1 - 4.5e-26 90.7 0.0 5.6e-26 90.4 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EWM29644.1 - 0.00014 21.8 0.0 0.00018 21.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone NDUF_B7 PF05676.8 EWM29645.1 - 3.8e-27 93.4 3.2 4.2e-27 93.3 2.2 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 EWM29645.1 - 0.00013 21.6 1.9 0.00014 21.5 1.1 1.3 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Yippee-Mis18 PF03226.9 EWM29646.1 - 2.6e-19 69.0 0.0 3.8e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TraB PF01963.12 EWM29647.1 - 5.5e-11 42.3 0.6 0.00034 20.1 0.1 2.5 2 0 0 2 2 2 2 TraB family His_Phos_1 PF00300.17 EWM29648.1 - 1.6e-57 194.0 0.0 1.9e-31 109.3 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Trypsin_2 PF13365.1 EWM29652.1 - 1.1e-13 51.1 0.0 2.5e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 EWM29652.1 - 1.1e-12 48.0 0.0 1.9e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.1 EWM29652.1 - 1.6e-10 40.7 0.0 1.2e-08 34.6 0.0 2.4 2 0 0 2 2 2 1 PDZ domain Peptidase_S7 PF00949.16 EWM29652.1 - 1.3e-05 24.5 0.4 2.6e-05 23.6 0.3 1.4 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S46 PF10459.4 EWM29652.1 - 0.0013 17.2 0.1 0.0019 16.7 0.1 1.1 1 0 0 1 1 1 1 Peptidase S46 PDZ PF00595.19 EWM29652.1 - 0.011 15.9 0.0 0.038 14.1 0.0 1.9 2 0 0 2 2 2 0 PDZ domain (Also known as DHR or GLGF) Trypsin_2 PF13365.1 EWM29653.1 - 8.2e-14 51.6 0.0 1.9e-13 50.4 0.0 1.6 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.21 EWM29653.1 - 7.5e-13 48.5 0.0 1.3e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.1 EWM29653.1 - 1e-10 41.3 0.0 9.3e-09 35.0 0.0 2.4 2 0 0 2 2 2 1 PDZ domain Peptidase_S7 PF00949.16 EWM29653.1 - 1e-05 24.9 0.4 2e-05 23.9 0.3 1.4 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S46 PF10459.4 EWM29653.1 - 0.0011 17.5 0.1 0.0015 17.0 0.1 1.1 1 0 0 1 1 1 1 Peptidase S46 PDZ PF00595.19 EWM29653.1 - 0.0076 16.4 0.0 0.03 14.4 0.0 2.0 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) Branch PF02485.16 EWM29654.1 - 4.4e-23 81.7 0.0 9.2e-23 80.6 0.0 1.4 1 0 0 1 1 1 1 Core-2/I-Branching enzyme tRNA_edit PF04073.10 EWM29655.1 - 4.2e-21 75.0 0.5 8e-21 74.1 0.3 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain tRNA-synt_2b PF00587.20 EWM29655.1 - 2.4e-20 72.8 0.0 4.3e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.6 EWM29655.1 - 4.7e-20 71.2 0.7 1.1e-19 70.1 0.5 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.15 EWM29655.1 - 1.1e-17 63.7 0.1 4.2e-17 61.8 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain Histone PF00125.19 EWM29656.1 - 8.1e-32 109.1 0.2 1.2e-31 108.5 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EWM29656.1 - 0.00012 22.2 0.0 0.00018 21.6 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EWM29656.1 - 0.02 14.9 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF367 PF04034.8 EWM29657.1 - 8.3e-48 161.1 0.0 1.2e-47 160.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EWM29657.1 - 6.6e-13 47.9 0.0 1.4e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Asparaginase_2 PF01112.13 EWM29658.1 - 3e-78 262.7 1.8 2.1e-77 260.0 1.2 1.8 1 1 0 1 1 1 1 Asparaginase DUF3082 PF11282.3 EWM29659.1 - 0.00096 19.1 3.1 0.0014 18.6 2.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3082) AWPM-19 PF05512.6 EWM29659.1 - 4.3 7.3 7.6 0.19 11.7 1.5 1.5 2 0 0 2 2 2 0 AWPM-19-like family SnoaL_2 PF12680.2 EWM29660.1 - 3.9e-12 46.4 0.0 6.9e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EWM29660.1 - 8.6e-07 28.5 0.2 1.5e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_4 PF13577.1 EWM29660.1 - 0.016 15.1 0.1 0.034 14.0 0.1 1.5 1 0 0 1 1 1 0 SnoaL-like domain PEN-2 PF10251.4 EWM29661.1 - 2.7e-14 53.1 0.6 1.1e-06 28.8 0.0 2.1 2 0 0 2 2 2 2 Presenilin enhancer-2 subunit of gamma secretase RabGAP-TBC PF00566.13 EWM29662.1 - 4.2e-41 140.7 4.2 7.5e-41 139.9 1.1 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Gtr1_RagA PF04670.7 EWM29662.1 - 0.065 12.3 0.1 0.39 9.7 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region PDZ PF00595.19 EWM29662.1 - 0.099 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) CM_2 PF01817.16 EWM29663.1 - 1.9e-06 27.8 1.1 0.0068 16.4 0.2 3.6 3 1 0 3 3 3 2 Chorismate mutase type II Peptidase_M41 PF01434.13 EWM29664.1 - 2.2e-45 154.7 0.3 3.3e-45 154.1 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EWM29664.1 - 1.7e-39 134.9 0.0 3.6e-39 133.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EWM29664.1 - 3.5e-07 30.0 0.9 7.4e-05 22.4 0.1 3.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EWM29664.1 - 1.4e-06 28.4 0.1 1.8e-05 24.8 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EWM29664.1 - 1.9e-06 28.0 0.5 0.021 14.9 0.0 3.3 2 1 1 3 3 3 2 AAA domain RuvB_N PF05496.7 EWM29664.1 - 2.9e-05 23.2 0.0 6.4e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EWM29664.1 - 4.7e-05 24.2 0.0 0.00012 22.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EWM29664.1 - 0.00033 20.5 0.0 0.0009 19.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EWM29664.1 - 0.00041 19.1 0.0 0.00065 18.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 EWM29664.1 - 0.00051 19.5 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.7 EWM29664.1 - 0.001 18.7 0.0 0.019 14.6 0.0 2.4 2 0 0 2 2 2 1 NACHT domain Mg_chelatase PF01078.16 EWM29664.1 - 0.0023 17.1 0.2 0.01 15.0 0.2 1.9 2 1 0 2 2 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EWM29664.1 - 0.0041 16.5 0.2 0.019 14.4 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 EWM29664.1 - 0.0049 16.7 0.0 0.029 14.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EWM29664.1 - 0.006 16.4 0.0 0.013 15.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EWM29664.1 - 0.0065 15.5 0.0 0.016 14.3 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_10 PF12846.2 EWM29664.1 - 0.0092 15.4 0.2 0.37 10.1 0.0 2.5 1 1 1 2 2 2 1 AAA-like domain AAA_19 PF13245.1 EWM29664.1 - 0.014 15.1 0.0 0.067 12.9 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA_18 PF13238.1 EWM29664.1 - 0.018 15.3 0.0 0.037 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EWM29664.1 - 0.034 14.4 0.1 0.11 12.7 0.0 2.0 1 1 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.21 EWM29664.1 - 0.074 12.5 0.0 0.33 10.4 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.1 EWM29664.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Glu-tRNAGln PF02686.10 EWM29665.1 - 3.1e-07 30.1 0.5 4.9e-07 29.4 0.4 1.3 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit Ras PF00071.17 EWM29666.1 - 2.2e-58 196.2 0.0 2.5e-58 196.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EWM29666.1 - 5.2e-22 78.5 0.0 8.2e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EWM29666.1 - 4.1e-13 48.9 0.0 4.3e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EWM29666.1 - 2.8e-05 23.3 0.0 3.4e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EWM29666.1 - 9e-05 21.9 0.0 0.0006 19.3 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EWM29666.1 - 0.00018 21.4 0.0 0.00024 21.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EWM29666.1 - 0.0019 17.3 0.0 0.0034 16.5 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EWM29666.1 - 0.0088 16.0 0.3 0.016 15.2 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.5 EWM29666.1 - 0.01 15.0 0.0 0.035 13.3 0.0 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.1 EWM29666.1 - 0.011 15.2 0.1 0.023 14.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EWM29666.1 - 0.018 15.1 0.0 0.049 13.7 0.0 1.8 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.1 EWM29666.1 - 0.02 14.3 0.0 0.061 12.8 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EWM29666.1 - 0.033 14.4 0.1 0.058 13.6 0.1 1.5 1 1 0 1 1 1 0 ABC transporter Septin PF00735.13 EWM29666.1 - 0.067 12.1 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Septin Hpr_kinase_C PF07475.7 EWM29666.1 - 0.085 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_5 PF07728.9 EWM29666.1 - 0.12 12.1 0.1 0.99 9.1 0.0 2.4 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 EWM29666.1 - 0.15 11.4 0.5 0.38 10.1 0.1 1.7 1 1 1 2 2 2 0 AAA-like domain DUF3641 PF12345.3 EWM29668.1 - 4.2e-50 169.0 0.0 8.1e-50 168.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3641) Radical_SAM PF04055.16 EWM29668.1 - 4.7e-09 36.6 0.0 3.1e-08 33.9 0.0 2.1 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.1 EWM29668.1 - 0.00019 21.5 0.0 0.00042 20.4 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EWM29668.1 - 0.0053 16.7 0.1 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain GpcrRhopsn4 PF10192.4 EWM29669.1 - 1.3e-38 132.6 0.2 1.9e-38 132.1 0.2 1.1 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain DUF485 PF04341.7 EWM29669.1 - 0.016 14.8 2.3 3.6 7.3 1.0 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Kua-UEV1_localn PF10520.4 EWM29670.1 - 4.3e-14 52.5 0.1 7.9e-14 51.7 0.1 1.4 1 0 0 1 1 1 1 Kua-ubiquitin conjugating enzyme hybrid localisation domain SdpI PF13630.1 EWM29670.1 - 2.4 7.9 8.1 1.1 9.0 0.2 2.8 3 0 0 3 3 3 0 SdpI/YhfL protein family PGA_cap PF09587.5 EWM29671.1 - 0.022 14.1 0.0 0.027 13.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap Peptidase_S28 PF05577.7 EWM29672.1 - 2.8e-66 223.8 0.0 6.6e-66 222.6 0.0 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Amino_oxidase PF01593.19 EWM29673.1 - 9.3e-06 24.9 1.4 7.3e-05 22.0 0.9 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EWM29673.1 - 3.1e-05 23.9 3.1 7.6e-05 22.6 0.5 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EWM29673.1 - 0.00033 19.6 8.0 0.026 13.3 0.0 2.5 3 0 0 3 3 3 2 FAD binding domain GMC_oxred_N PF00732.14 EWM29673.1 - 0.0021 17.2 0.0 0.0037 16.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase HI0933_like PF03486.9 EWM29673.1 - 0.023 13.1 0.3 0.54 8.6 0.2 2.1 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.9 EWM29673.1 - 0.099 12.5 1.3 0.76 9.6 0.1 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Arm PF00514.18 EWM29674.1 - 1.1e-24 85.2 24.6 0.0015 18.3 0.0 12.7 14 0 0 14 14 14 8 Armadillo/beta-catenin-like repeat U-box PF04564.10 EWM29674.1 - 3.4e-13 49.3 0.0 1.1e-12 47.6 0.0 1.9 2 0 0 2 2 2 1 U-box domain Atx10homo_assoc PF09759.4 EWM29674.1 - 4.3e-09 36.0 8.8 0.33 10.7 0.1 8.0 8 1 2 10 10 10 4 Spinocerebellar ataxia type 10 protein domain zf-Nse PF11789.3 EWM29674.1 - 2.6e-05 23.6 0.0 6e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EWM29674.1 - 0.1 12.3 0.0 0.51 10.1 0.0 2.2 2 0 0 2 2 2 0 RING-type zinc-finger SNF2_N PF00176.18 EWM29676.1 - 6e-34 117.1 0.0 8.8e-34 116.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EWM29676.1 - 1.3e-05 24.9 0.0 2.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EWM29676.1 - 0.00026 20.8 0.0 0.00099 18.9 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EWM29676.1 - 0.0037 16.7 0.0 0.0066 15.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TRAUB PF08164.7 EWM29678.1 - 2.4e-14 53.1 0.3 8.3e-14 51.4 0.0 2.0 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 EWM29678.1 - 2.9e-12 46.8 2.1 6e-12 45.8 0.0 2.1 2 0 0 2 2 2 1 Apoptosis antagonizing transcription factor Daxx PF03344.10 EWM29678.1 - 2.2 6.6 11.0 2.9 6.2 7.6 1.1 1 0 0 1 1 1 0 Daxx Family YL1 PF05764.8 EWM29678.1 - 3.1 7.3 17.5 0.13 11.8 8.3 1.4 2 0 0 2 2 2 0 YL1 nuclear protein SET PF00856.23 EWM29679.1 - 9.2e-18 65.0 0.1 1.2e-16 61.4 0.0 2.1 2 0 0 2 2 2 1 SET domain Nop16 PF09420.5 EWM29681.1 - 8.4e-09 35.7 0.5 0.00025 21.1 0.2 2.0 1 1 1 2 2 2 2 Ribosome biogenesis protein Nop16 LRR_6 PF13516.1 EWM29682.1 - 9.2e-33 108.6 7.4 0.00047 19.9 0.0 11.6 11 0 0 11 11 11 8 Leucine Rich repeat LRR_8 PF13855.1 EWM29682.1 - 1.7e-15 56.4 3.9 0.0017 18.0 0.1 5.8 2 2 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 EWM29682.1 - 1.8e-15 56.1 0.0 0.011 15.3 0.0 6.0 3 2 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EWM29682.1 - 8.7e-10 37.2 1.3 14 6.2 0.0 9.0 9 1 0 9 9 9 1 Leucine Rich Repeat LRR_7 PF13504.1 EWM29682.1 - 6.3e-07 28.5 11.3 25 5.6 0.0 9.6 10 0 0 10 10 10 1 Leucine rich repeat CDP-OH_P_transf PF01066.16 EWM29685.1 - 1.5e-18 66.9 1.3 1.5e-18 66.9 0.9 1.8 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Gly_transf_sug PF04488.10 EWM29686.1 - 1.3e-10 41.6 0.0 2.6e-10 40.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EWM29686.1 - 7.1e-05 22.0 0.0 0.00011 21.4 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.2 EWM29686.1 - 0.00022 19.8 0.0 0.00035 19.1 0.0 1.2 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain Isochorismatase PF00857.15 EWM29687.1 - 2.4e-34 118.7 0.0 2.8e-34 118.5 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family AFOR_N PF02730.10 EWM29687.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, N-terminal domain NifU_N PF01592.11 EWM29688.1 - 8.9e-51 171.1 0.1 1.1e-50 170.7 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain AAA_25 PF13481.1 EWM29689.1 - 2.7e-05 23.6 0.0 0.012 15.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EWM29689.1 - 0.0008 19.1 0.0 0.0015 18.1 0.0 1.5 1 1 0 1 1 1 1 NACHT domain RNA_helicase PF00910.17 EWM29689.1 - 0.0032 17.6 0.0 0.036 14.2 0.0 2.1 2 0 0 2 2 2 1 RNA helicase AAA PF00004.24 EWM29689.1 - 0.0065 16.6 0.0 2.7 8.2 0.0 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EWM29689.1 - 0.0067 16.4 1.1 0.23 11.4 0.7 2.5 1 1 1 2 2 2 1 AAA ATPase domain Terminase_4 PF05119.7 EWM29689.1 - 0.03 14.4 0.0 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 Phage terminase, small subunit AAA_14 PF13173.1 EWM29689.1 - 0.076 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain PSII_BNR PF14870.1 EWM29690.1 - 1e-121 405.6 2.4 1.3e-121 405.3 1.6 1.0 1 0 0 1 1 1 1 Photosynthesis system II assembly factor YCF48 BNR PF02012.15 EWM29690.1 - 2.7e-07 29.4 8.0 2 8.5 0.0 6.0 6 0 0 6 6 6 4 BNR/Asp-box repeat TAT_signal PF10518.4 EWM29690.1 - 0.011 15.7 4.4 0.011 15.7 3.0 3.1 3 0 0 3 3 3 0 TAT (twin-arginine translocation) pathway signal sequence UCR_Fe-S_N PF10399.4 EWM29690.1 - 7.3 5.8 9.8 4.6 6.4 0.3 2.5 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal peroxidase PF00141.18 EWM29691.1 - 3.6e-44 150.9 0.0 7.1e-44 149.9 0.0 1.5 1 1 0 1 1 1 1 Peroxidase EcoRII-N PF09217.5 EWM29691.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease EcoRII, N-terminal Glyco_hydro_31 PF01055.21 EWM29692.1 - 4.6e-74 249.8 0.0 6.6e-74 249.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Pol_alpha_B_N PF08418.5 EWM29693.1 - 0.048 13.1 1.1 0.057 12.9 0.8 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Stm1_N PF09598.5 EWM29693.1 - 4.6 8.0 11.2 9.4 7.0 7.8 1.5 1 0 0 1 1 1 0 Stm1 Condensation PF00668.15 EWM29694.1 - 4.5e-05 22.4 0.0 0.00045 19.1 0.0 2.0 1 1 0 1 1 1 1 Condensation domain WES_acyltransf PF03007.11 EWM29694.1 - 5.2e-05 22.9 0.0 0.31 10.5 0.0 2.5 2 0 0 2 2 2 2 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.8 EWM29694.1 - 6.5e-05 22.7 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) Metallothio_Pro PF02069.11 EWM29694.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic metallothionein DUF1604 PF07713.8 EWM29695.1 - 0.055 13.2 0.7 0.14 11.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1604) PCIF1_WW PF12237.3 EWM29696.1 - 2.3e-52 176.8 0.0 1.9e-49 167.3 0.0 2.3 2 0 0 2 2 2 2 Phosphorylated CTD interacting factor 1 WW domain Abhydrolase_3 PF07859.8 EWM29697.1 - 1.3e-61 207.8 0.2 5.8e-61 205.7 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.23 EWM29697.1 - 2.4e-09 36.4 0.2 7e-09 34.9 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EWM29697.1 - 9.2e-09 34.8 0.0 4.6e-08 32.5 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EWM29697.1 - 9.7e-09 35.1 0.1 2.3e-08 33.9 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF2424 PF10340.4 EWM29697.1 - 0.066 11.8 0.0 0.13 10.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) DLH PF01738.13 EWM29697.1 - 0.13 11.4 0.0 0.97 8.6 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family AXE1 PF05448.7 EWM29697.1 - 0.18 10.2 0.0 0.29 9.5 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Glucan_synthase PF02364.10 EWM29698.1 - 3.1e-177 591.0 14.6 1.4e-154 516.0 8.3 2.7 1 1 1 2 2 2 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EWM29698.1 - 1.5e-27 95.7 0.5 4.4e-27 94.3 0.4 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 RRM_1 PF00076.17 EWM29699.1 - 5.1e-24 83.7 0.3 9e-13 47.6 0.0 3.9 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM29699.1 - 7.5e-23 80.2 0.5 8.1e-14 51.3 0.0 3.5 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM29699.1 - 1.3e-07 31.3 0.6 0.00082 19.1 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4140 PF13600.1 EWM29699.1 - 0.0027 18.1 0.2 4.9 7.6 0.0 3.0 3 0 0 3 3 3 2 N-terminal domain of unknown function (DUF4140) Spo7_2_N PF15407.1 EWM29699.1 - 0.023 14.1 0.0 1.1 8.7 0.0 2.5 2 0 0 2 2 2 0 Sporulation protein family 7 Sec63 PF02889.11 EWM29702.1 - 3.3e-146 486.4 0.0 1.9e-94 316.4 0.0 2.6 2 1 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EWM29702.1 - 4.8e-59 198.6 0.5 2.1e-29 102.1 0.0 3.4 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EWM29702.1 - 5e-17 61.5 0.1 3.6e-08 33.1 0.0 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 EWM29702.1 - 3.1e-16 59.7 0.0 1.2e-08 34.9 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EWM29702.1 - 3.9e-07 30.2 0.2 0.043 13.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 EWM29702.1 - 5.1e-05 22.6 0.1 0.3 10.3 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein T2SE PF00437.15 EWM29702.1 - 0.00033 19.6 0.0 0.77 8.5 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein IstB_IS21 PF01695.12 EWM29702.1 - 0.00091 18.6 0.2 0.44 9.9 0.0 3.1 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.1 EWM29702.1 - 0.0062 16.2 0.7 2.5 7.8 0.1 3.1 2 0 0 2 2 2 1 Part of AAA domain AAA_10 PF12846.2 EWM29702.1 - 0.01 15.3 0.8 5.9 6.2 0.0 3.9 3 1 0 4 4 4 0 AAA-like domain AAA PF00004.24 EWM29702.1 - 0.017 15.3 0.4 2 8.5 0.0 3.7 3 2 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.16 EWM29702.1 - 0.026 13.8 0.1 7 5.8 0.0 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Sigma54_activat PF00158.21 EWM29702.1 - 0.15 11.5 0.0 7.2 6.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_23 PF13476.1 EWM29702.1 - 0.16 12.3 0.0 7.6 6.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EWM29702.1 - 0.16 11.0 0.1 16 4.4 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin CBS PF00571.23 EWM29703.1 - 1.2e-21 76.1 1.1 1.8e-11 43.6 0.0 2.6 2 0 0 2 2 2 2 CBS domain DHH PF01368.15 EWM29703.1 - 7.3e-11 41.9 0.5 1.5e-10 40.8 0.1 1.6 2 0 0 2 2 2 1 DHH family DHHA1 PF02272.14 EWM29703.1 - 0.0017 18.0 0.4 0.0041 16.7 0.3 1.6 1 0 0 1 1 1 1 DHHA1 domain Acetyltransf_10 PF13673.1 EWM29703.1 - 0.048 13.7 0.0 0.16 12.1 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Hexapep_2 PF14602.1 EWM29704.1 - 2.3e-06 27.0 14.9 0.25 10.9 0.2 6.2 5 1 0 6 6 6 3 Hexapeptide repeat of succinyl-transferase PP-binding PF00550.20 EWM29704.1 - 2.5e-06 27.6 0.1 4.4e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.19 EWM29704.1 - 0.00014 21.1 22.0 0.032 13.7 0.4 7.8 9 0 0 9 9 9 3 Bacterial transferase hexapeptide (six repeats) HEAT PF02985.17 EWM29705.1 - 9.6e-20 68.8 20.0 0.076 13.1 0.0 11.5 11 0 0 11 11 11 4 HEAT repeat HEAT_2 PF13646.1 EWM29705.1 - 4.4e-16 58.9 17.8 0.00015 22.0 0.0 9.7 5 5 6 11 11 11 5 HEAT repeats HEAT_EZ PF13513.1 EWM29705.1 - 2.9e-13 49.8 26.2 2.1e-05 24.8 0.0 10.6 11 3 1 12 12 10 4 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EWM29705.1 - 1e-09 38.6 0.0 4.2e-06 27.0 0.0 5.0 4 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EWM29705.1 - 9.9e-08 32.0 0.4 0.27 11.0 0.0 6.2 6 1 1 7 7 7 1 non-SMC mitotic condensation complex subunit 1 IFRD PF05004.8 EWM29705.1 - 5.7e-07 28.9 7.8 0.0031 16.6 0.0 3.5 3 1 1 4 4 4 2 Interferon-related developmental regulator (IFRD) DUF2454 PF10521.4 EWM29705.1 - 2.3e-06 26.8 0.0 0.00041 19.4 0.0 3.7 2 1 1 3 3 3 1 Protein of unknown function (DUF2454) IBN_N PF03810.14 EWM29705.1 - 3.1e-06 27.0 0.9 1.6e-05 24.7 0.0 2.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain CLASP_N PF12348.3 EWM29705.1 - 5.9e-06 25.7 4.1 0.0018 17.7 0.0 5.6 6 2 1 8 8 8 1 CLASP N terminal RIX1 PF08167.7 EWM29705.1 - 6.3e-06 25.9 2.6 0.62 9.7 0.0 5.1 3 2 3 6 6 6 2 rRNA processing/ribosome biogenesis DUF577 PF04510.7 EWM29705.1 - 7.6e-06 25.7 0.2 0.00016 21.4 0.2 2.4 2 0 0 2 2 2 1 Family of unknown function (DUF577) Ipi1_N PF12333.3 EWM29705.1 - 1e-05 25.4 0.5 0.37 10.8 0.0 4.3 3 1 1 4 4 4 2 Rix1 complex component involved in 60S ribosome maturation Arm PF00514.18 EWM29705.1 - 4.5e-05 23.1 10.4 0.57 10.1 0.1 7.6 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat ParcG PF10274.4 EWM29705.1 - 0.00051 19.9 0.1 0.95 9.3 0.0 4.8 4 1 1 5 5 5 1 Parkin co-regulated protein Adaptin_N PF01602.15 EWM29705.1 - 0.0006 18.2 3.9 0.21 9.8 0.0 5.2 5 2 1 6 6 6 1 Adaptin N terminal region DUF3385 PF11865.3 EWM29705.1 - 0.076 12.9 1.8 31 4.4 0.1 4.8 6 0 0 6 6 6 0 Domain of unknown function (DUF3385) MMS19_C PF12460.3 EWM29705.1 - 0.43 9.2 5.3 15 4.1 0.0 4.6 5 2 0 5 5 5 0 RNAPII transcription regulator C-terminal INSIG PF07281.7 EWM29706.1 - 6.3e-10 38.7 0.6 1.3e-09 37.7 0.4 1.4 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) Pribosyltran_N PF13793.1 EWM29707.1 - 8.3e-50 167.3 0.7 7.5e-49 164.3 0.1 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EWM29707.1 - 6e-25 88.0 2.5 7.2e-25 87.8 0.5 2.0 2 1 1 3 3 3 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EWM29707.1 - 8.8e-10 38.3 1.5 1.7e-09 37.4 0.5 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain HTH_31 PF13560.1 EWM29707.1 - 0.087 13.0 1.1 0.25 11.5 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain TraL PF07178.6 EWM29707.1 - 0.1 12.6 0.1 0.24 11.4 0.1 1.6 1 0 0 1 1 1 0 TraL protein WD40 PF00400.27 EWM29709.1 - 3.7e-28 96.3 8.5 2.3e-07 30.4 0.1 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat BBS2_Mid PF14783.1 EWM29709.1 - 0.013 15.2 0.3 0.26 11.0 0.0 3.0 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 EWM29709.1 - 0.077 11.1 1.9 3.1 5.8 1.3 2.2 1 1 0 1 1 1 0 Nucleoporin Nup120/160 MORN PF02493.15 EWM29710.1 - 6.2e-48 157.7 45.1 3.5e-07 29.5 0.9 9.7 9 0 0 9 9 9 9 MORN repeat Peptidase_S9_N PF02897.10 EWM29711.1 - 2.1e-83 280.2 0.0 3.2e-83 279.6 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 EWM29711.1 - 1.1e-57 194.7 0.0 2.5e-57 193.5 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.7 EWM29711.1 - 0.0079 14.7 0.0 0.016 13.7 0.0 1.4 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.8 EWM29711.1 - 0.031 13.8 0.0 0.33 10.4 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Porin_3 PF01459.17 EWM29712.1 - 9.9e-45 152.9 0.0 1.2e-44 152.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic porin UnbV_ASPIC PF07593.7 EWM29712.1 - 0.0078 15.8 0.0 0.027 14.1 0.0 1.9 1 0 0 1 1 1 1 ASPIC and UnbV FYRC PF05965.9 EWM29712.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 F/Y rich C-terminus Pantoate_ligase PF02569.10 EWM29713.1 - 1.9e-52 177.7 0.0 2e-52 177.6 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Ras PF00071.17 EWM29714.1 - 6e-59 198.0 0.1 8.5e-59 197.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EWM29714.1 - 1.7e-20 73.6 0.0 3.3e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EWM29714.1 - 1.7e-14 53.4 0.1 2.6e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EWM29714.1 - 3.4e-06 26.6 0.0 7.9e-06 25.4 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EWM29714.1 - 2.8e-05 23.3 0.1 4.4e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EWM29714.1 - 0.00016 20.9 0.0 0.00036 19.8 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EWM29714.1 - 0.00062 19.7 0.1 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EWM29714.1 - 0.02 15.0 0.0 0.15 12.2 0.0 2.3 2 1 1 3 3 3 0 AAA domain CbiA PF01656.18 EWM29714.1 - 0.063 12.6 0.0 4.5 6.6 0.0 2.1 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF258 PF03193.11 EWM29714.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Mannosyl_trans3 PF11051.3 EWM29715.1 - 2.6e-32 112.2 0.0 4.1e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative PP1_inhibitor PF05361.7 EWM29716.1 - 5.1e-09 35.9 1.4 6.4e-09 35.6 0.9 1.1 1 0 0 1 1 1 1 PKC-activated protein phosphatase-1 inhibitor SAPS PF04499.10 EWM29717.1 - 9.7e-05 21.1 0.0 0.0037 15.9 0.0 2.6 3 0 0 3 3 3 2 SIT4 phosphatase-associated protein BLVR PF06375.6 EWM29717.1 - 0.12 12.2 3.3 0.094 12.5 0.5 2.0 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) BCDHK_Adom3 PF10436.4 EWM29718.1 - 1.6e-28 99.2 0.0 2.4e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EWM29718.1 - 6.5e-15 54.8 0.0 1.1e-13 50.8 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EWM29718.1 - 0.00031 20.4 0.0 0.00061 19.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase S_tail_recep_bd PF14928.1 EWM29718.1 - 0.12 12.5 0.0 10 6.3 0.0 2.4 2 0 0 2 2 2 0 Short tail fibre protein receptor-binding domain Myelin_MBP PF01669.12 EWM29720.1 - 0.058 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Myelin basic protein MYEOV2 PF15004.1 EWM29722.1 - 0.0044 17.5 0.2 0.0073 16.8 0.1 1.3 1 0 0 1 1 1 1 Myeloma-overexpressed-like Amidohydro_1 PF01979.15 EWM29723.1 - 5e-38 131.5 0.0 3e-25 89.5 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EWM29723.1 - 1.4e-07 31.2 0.0 3.3e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EWM29723.1 - 3.3e-06 27.3 0.3 0.068 13.1 0.0 2.6 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 EWM29723.1 - 5.1e-06 25.9 0.4 0.1 11.7 0.0 3.0 4 0 0 4 4 4 2 Amidohydrolase family A_deaminase PF00962.17 EWM29723.1 - 0.026 13.4 0.0 0.23 10.3 0.0 2.0 1 1 1 2 2 2 0 Adenosine/AMP deaminase ketoacyl-synt PF00109.21 EWM29724.1 - 2.5e-89 299.1 0.1 4.8e-89 298.1 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.23 EWM29724.1 - 1e-72 244.8 0.0 1.4e-72 244.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Acyl_transf_1 PF00698.16 EWM29724.1 - 1.6e-58 198.5 0.0 3e-58 197.6 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EWM29724.1 - 1.9e-45 153.5 0.0 7.1e-45 151.6 0.0 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EWM29724.1 - 5.9e-11 42.4 0.2 1.5e-10 41.1 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EWM29724.1 - 7.1e-05 21.9 0.2 0.00017 20.6 0.2 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain AMP-binding_C_2 PF14535.1 EWM29724.1 - 0.13 12.3 0.1 0.4 10.7 0.1 1.9 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Arf PF00025.16 EWM29725.1 - 2.3e-74 248.3 0.0 2.6e-74 248.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EWM29725.1 - 7.4e-13 48.2 0.0 8.6e-13 47.9 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EWM29725.1 - 1.7e-12 46.7 0.3 1.6e-08 33.6 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EWM29725.1 - 2e-12 46.6 0.0 2.5e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EWM29725.1 - 6.8e-10 39.4 0.0 8.9e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EWM29725.1 - 5.5e-09 35.9 0.0 7.6e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EWM29725.1 - 2.8e-08 33.2 0.0 3.3e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 EWM29725.1 - 1.9e-06 27.2 0.8 1.5e-05 24.2 0.5 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EWM29725.1 - 0.0025 17.3 0.1 0.67 9.3 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain ArgK PF03308.11 EWM29725.1 - 0.0048 15.7 0.2 0.54 8.9 0.1 2.8 2 1 0 2 2 2 1 ArgK protein AAA_18 PF13238.1 EWM29725.1 - 0.022 15.0 0.0 0.028 14.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EWM29725.1 - 0.037 14.3 0.1 0.089 13.0 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Bromodomain PF00439.20 EWM29726.1 - 1.2e-16 60.4 0.0 2.4e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Bromodomain TIG PF01833.19 EWM29726.1 - 2e-08 34.1 0.0 9.6e-08 31.9 0.0 2.0 2 0 0 2 2 2 1 IPT/TIG domain Rad17 PF03215.10 EWM29726.1 - 3.3e-06 26.0 0.2 0.098 11.3 0.0 3.1 3 0 0 3 3 3 2 Rad17 cell cycle checkpoint protein AAA PF00004.24 EWM29726.1 - 6.2e-06 26.4 0.0 3.4e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EWM29726.1 - 0.0012 19.6 0.0 0.006 17.4 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EWM29726.1 - 0.0032 17.6 0.0 0.01 15.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EWM29726.1 - 0.0094 15.9 0.0 0.035 14.1 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 EWM29726.1 - 0.0095 15.8 0.0 0.042 13.7 0.0 2.1 1 0 0 1 1 1 1 AAA domain HTH_5 PF01022.15 EWM29726.1 - 0.045 13.4 0.5 0.19 11.3 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family DUF815 PF05673.8 EWM29726.1 - 0.061 12.2 0.2 0.18 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_29 PF13555.1 EWM29726.1 - 0.17 11.4 0.0 0.41 10.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glyco_transf_28 PF03033.15 EWM29727.1 - 4.5e-20 71.8 0.2 2e-19 69.7 0.2 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain ATG_C PF09333.6 EWM29727.1 - 1.3e-06 28.4 0.0 3.1e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 ATG C terminal domain PH PF00169.24 EWM29727.1 - 2.4e-06 27.7 0.0 5.3e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 PH domain PH_11 PF15413.1 EWM29727.1 - 0.00045 20.4 0.1 0.0044 17.2 0.1 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain Glyco_tran_28_C PF04101.11 EWM29727.1 - 0.001 18.7 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.13 EWM29727.1 - 0.0019 16.8 0.0 0.0031 16.1 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_8 PF15409.1 EWM29727.1 - 0.034 14.2 0.4 0.14 12.2 0.1 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain RPE65 PF03055.10 EWM29728.1 - 1.4e-121 406.4 0.0 1.6e-121 406.2 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF1168 PF06658.7 EWM29730.1 - 2.3e-07 30.4 17.9 2.8e-07 30.1 12.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Remorin_C PF03763.8 EWM29730.1 - 0.13 11.7 11.9 0.18 11.3 8.2 1.3 1 0 0 1 1 1 0 Remorin, C-terminal region NARP1 PF12569.3 EWM29730.1 - 0.89 8.2 7.3 0.84 8.3 5.1 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 ERK-JNK_inhib PF15002.1 EWM29730.1 - 1.4 8.2 8.1 0.93 8.8 4.6 1.4 1 1 0 1 1 1 0 ERK and JNK pathways, inhibitor Vfa1 PF08432.5 EWM29730.1 - 2.2 8.2 8.4 2.8 7.9 5.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3395 PF11875.3 EWM29730.1 - 4.8 6.8 7.0 6.1 6.4 4.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) RNase_H2-Ydr279 PF09468.5 EWM29730.1 - 5.5 6.0 6.9 7.9 5.5 4.8 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Enolase_C PF00113.17 EWM29732.1 - 4.1e-154 511.8 0.8 4.1e-154 511.8 0.5 1.5 2 0 0 2 2 2 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EWM29732.1 - 7.3e-60 200.6 0.2 1.5e-59 199.6 0.2 1.6 1 0 0 1 1 1 1 Enolase, N-terminal domain MAAL_C PF07476.6 EWM29732.1 - 1.5e-05 24.0 0.7 2.2e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_C PF13378.1 EWM29732.1 - 0.017 15.0 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 Enolase C-terminal domain-like DUF1449 PF07290.6 EWM29732.1 - 0.035 13.4 0.0 0.94 8.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1449) YbjQ_1 PF01906.12 EWM29732.1 - 0.098 13.0 0.5 0.7 10.3 0.1 2.7 3 0 0 3 3 3 0 Putative heavy-metal-binding Snf7 PF03357.16 EWM29733.1 - 3.1e-18 65.7 7.4 3.7e-18 65.4 5.1 1.1 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.9 EWM29733.1 - 0.00015 21.2 3.0 0.00023 20.6 2.1 1.3 1 1 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Cortex-I_coil PF09304.5 EWM29733.1 - 0.0012 18.8 1.4 0.0028 17.6 0.9 1.6 1 0 0 1 1 1 1 Cortexillin I, coiled coil DUF4172 PF13776.1 EWM29733.1 - 0.03 14.3 0.7 0.61 10.2 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4172) Hamartin PF04388.7 EWM29733.1 - 0.095 11.3 0.9 0.11 11.1 0.6 1.1 1 0 0 1 1 1 0 Hamartin protein DUF650 PF04894.7 EWM29733.1 - 0.16 11.4 0.5 0.35 10.3 0.3 1.6 1 1 0 1 1 1 0 Archaeal protein of unknown function (DUF650) Fib_alpha PF08702.5 EWM29733.1 - 0.17 12.0 3.7 0.82 9.7 0.0 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Peptidase_C97 PF05903.9 EWM29734.1 - 1.4e-28 99.5 0.0 1.9e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain Flavokinase PF01687.12 EWM29736.1 - 1.3e-34 118.8 0.0 1.6e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Peptidase_C1 PF00112.18 EWM29737.1 - 7e-55 186.2 0.8 9.2e-55 185.8 0.5 1.1 1 0 0 1 1 1 1 Papain family cysteine protease E1_DerP2_DerF2 PF02221.10 EWM29737.1 - 3.1e-12 46.8 0.2 3.1e-12 46.8 0.1 1.7 2 0 0 2 2 2 1 ML domain Propeptide_C1 PF08127.8 EWM29737.1 - 0.00086 18.8 0.2 0.0017 17.9 0.1 1.4 1 0 0 1 1 1 1 Peptidase family C1 propeptide TRP_N PF14558.1 EWM29737.1 - 0.026 14.5 0.9 0.18 11.8 0.6 2.1 1 1 0 1 1 1 0 ML-like domain Kelch_1 PF01344.20 EWM29738.1 - 4.4e-77 253.4 12.5 1.9e-16 59.3 0.0 6.7 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.1 EWM29738.1 - 1.9e-49 163.9 2.0 1.6e-09 37.5 0.0 6.5 2 2 4 6 6 6 6 Kelch motif Kelch_2 PF07646.10 EWM29738.1 - 2e-34 116.0 5.9 7.7e-08 31.8 0.0 7.0 7 0 0 7 7 7 5 Kelch motif Kelch_4 PF13418.1 EWM29738.1 - 4.3e-30 103.2 1.5 7.9e-06 25.5 0.0 6.6 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.1 EWM29738.1 - 3.1e-29 100.4 7.8 8.1e-07 29.0 0.0 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain BACK PF07707.10 EWM29738.1 - 8.6e-27 92.9 0.1 2.4e-26 91.5 0.1 1.8 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.26 EWM29738.1 - 1e-26 93.0 0.1 9.4e-26 89.9 0.0 2.1 1 1 1 2 2 2 1 BTB/POZ domain Kelch_5 PF13854.1 EWM29738.1 - 3.3e-08 33.3 12.7 0.84 9.6 0.0 6.5 6 0 0 6 6 6 4 Kelch motif Skp1 PF01466.14 EWM29738.1 - 0.14 12.1 0.1 0.31 11.0 0.1 1.5 1 0 0 1 1 1 0 Skp1 family, dimerisation domain Herpes_UL49_1 PF03117.9 EWM29742.1 - 0.34 9.9 0.0 0.54 9.3 0.0 1.2 1 0 0 1 1 1 0 UL49 family RRM_1 PF00076.17 EWM29744.1 - 5.2e-09 35.6 0.2 1e-08 34.6 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM29744.1 - 1.1e-06 28.5 0.0 1.5e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Thioredoxin PF00085.15 EWM29745.1 - 4e-62 206.4 0.0 7.7e-31 105.8 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 EWM29745.1 - 1.9e-19 70.0 0.3 3.8e-19 69.1 0.2 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 EWM29745.1 - 6.1e-14 52.1 0.2 1e-05 25.6 0.0 3.6 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EWM29745.1 - 3.3e-12 46.2 0.0 2.3e-05 24.3 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 EWM29745.1 - 7.6e-08 32.3 0.0 0.01 15.9 0.0 3.4 2 2 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 EWM29745.1 - 5.7e-06 26.0 0.1 0.073 12.7 0.0 2.7 3 0 0 3 3 3 2 AhpC/TSA family ERp29_N PF07912.8 EWM29745.1 - 0.0003 20.7 0.0 0.068 13.1 0.0 2.8 3 0 0 3 3 3 1 ERp29, N-terminal domain Redoxin PF08534.5 EWM29745.1 - 0.00047 19.7 0.2 0.41 10.1 0.0 2.3 2 0 0 2 2 2 2 Redoxin Thioredoxin_6 PF13848.1 EWM29745.1 - 0.0005 19.9 0.0 0.013 15.2 0.0 2.8 1 1 1 2 2 2 1 Thioredoxin-like domain HyaE PF07449.6 EWM29745.1 - 0.0055 16.5 0.0 3.7 7.4 0.0 2.7 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.1 EWM29745.1 - 0.075 12.5 0.1 6.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_4 PF13462.1 EWM29745.1 - 0.14 12.1 0.0 19 5.2 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin PITH PF06201.8 EWM29746.1 - 7.2e-37 126.5 0.0 8.7e-37 126.2 0.0 1.1 1 0 0 1 1 1 1 PITH domain IER PF05760.7 EWM29747.1 - 0.011 15.7 0.1 0.012 15.5 0.1 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) Tim17 PF02466.14 EWM29748.1 - 1.6e-06 28.2 2.9 1.6e-06 28.2 2.0 2.1 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_Omp PF13488.1 EWM29748.1 - 0.051 13.2 12.6 0.93 9.1 1.8 2.6 2 0 0 2 2 2 0 Glycine zipper Gly-zipper_OmpA PF13436.1 EWM29748.1 - 0.096 12.3 10.5 0.16 11.6 0.6 2.2 1 1 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_YMGG PF13441.1 EWM29748.1 - 3.1 7.3 18.6 0.65 9.5 1.9 2.4 2 0 0 2 2 2 0 YMGG-like Gly-zipper Mito_carr PF00153.22 EWM29749.1 - 5e-35 119.0 0.0 1.8e-10 40.3 0.0 4.6 3 3 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.20 EWM29750.1 - 2e-57 194.2 0.0 3.5e-57 193.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM29750.1 - 4.7e-29 101.2 0.0 7.7e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EWM29750.1 - 1.2e-05 24.4 0.0 2.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EWM29750.1 - 0.0025 17.6 0.0 0.0025 17.6 0.0 2.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Peptidase_C12 PF01088.16 EWM29750.1 - 0.061 12.4 1.9 0.17 11.0 1.3 1.7 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase, family 1 DASH_Dad3 PF08656.5 EWM29750.1 - 0.082 12.6 1.4 0.29 10.8 1.0 2.0 1 0 0 1 1 1 0 DASH complex subunit Dad3 FlxA PF14282.1 EWM29750.1 - 2 8.3 12.1 0.21 11.5 3.2 2.8 2 0 0 2 2 2 0 FlxA-like protein DUF972 PF06156.8 EWM29750.1 - 3.5 8.0 14.7 3.7 7.9 4.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF972) PAT1 PF09770.4 EWM29751.1 - 5.6 5.0 18.2 8.9 4.4 12.6 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med14 PF08638.6 EWM29753.1 - 3.1e-16 59.2 0.0 6.6e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit MED14 GTP_EFTU PF00009.22 EWM29754.1 - 7.1e-48 162.5 0.0 5.3e-47 159.6 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EWM29754.1 - 1.1e-13 50.8 0.0 4.2e-13 48.9 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.1 EWM29754.1 - 1.8e-10 40.5 0.0 4.2e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EWM29754.1 - 5.1e-08 32.9 0.0 1.4e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 EWM29754.1 - 0.043 13.3 0.0 0.13 11.8 0.0 1.8 1 0 0 1 1 1 0 Elongation factor G, domain IV Semialdhyde_dhC PF02774.13 EWM29755.1 - 1.7e-45 155.1 0.0 3e-45 154.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EWM29755.1 - 2.5e-29 102.0 0.1 9.2e-29 100.2 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EWM29755.1 - 0.0067 16.4 0.1 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding zf-RING_2 PF13639.1 EWM29757.1 - 5.6e-12 45.3 14.5 9.2e-12 44.6 10.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EWM29757.1 - 4.6e-08 33.0 7.7 8.9e-08 32.1 5.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EWM29757.1 - 1.6e-06 27.6 11.7 2.8e-06 26.9 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EWM29757.1 - 0.0002 21.3 17.5 0.00035 20.5 12.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EWM29757.1 - 0.00026 20.6 15.9 0.00045 19.8 11.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EWM29757.1 - 0.01 15.4 17.0 0.018 14.7 11.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EWM29757.1 - 0.94 9.3 11.2 3.5 7.5 7.8 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EWM29757.1 - 1.2 8.8 8.0 3.9 7.2 5.5 1.9 1 1 0 1 1 1 0 RING-type zinc-finger Methyltransf_31 PF13847.1 EWM29758.1 - 4.2e-09 36.1 0.0 7.2e-09 35.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM29758.1 - 2.5e-07 31.0 0.0 4.7e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM29758.1 - 3.7e-07 30.6 0.0 5.6e-07 30.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM29758.1 - 2.2e-05 24.7 0.0 3.6e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM29758.1 - 4.7e-05 23.7 0.0 0.00013 22.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM29758.1 - 0.01 15.8 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EWM29758.1 - 0.1 12.2 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain HD_4 PF13328.1 EWM29759.1 - 8.1e-44 149.0 0.4 1.8e-43 147.8 0.3 1.6 1 0 0 1 1 1 1 HD domain HD PF01966.17 EWM29759.1 - 3.4e-07 30.2 0.1 8.3e-07 29.0 0.1 1.7 1 0 0 1 1 1 1 HD domain TGS PF02824.16 EWM29759.1 - 0.00016 21.3 0.1 0.0042 16.8 0.0 2.7 3 0 0 3 3 3 1 TGS domain Chloroa_b-bind PF00504.16 EWM29759.1 - 0.0051 17.0 0.6 0.14 12.4 0.1 2.7 2 0 0 2 2 2 1 Chlorophyll A-B binding protein RelA_SpoT PF04607.12 EWM29759.1 - 0.022 14.7 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Region found in RelA / SpoT proteins SMC_N PF02463.14 EWM29760.1 - 4.8e-25 88.0 0.0 1.2e-24 86.7 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EWM29760.1 - 5.4e-19 69.3 12.3 4.5e-18 66.3 0.0 3.7 3 1 0 3 3 3 1 AAA domain AAA_21 PF13304.1 EWM29760.1 - 5.6e-06 26.5 0.0 1.7e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EWM29760.1 - 4.6e-05 22.8 0.0 0.00011 21.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EWM29760.1 - 0.00024 21.9 1.1 0.0019 19.0 0.8 2.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EWM29760.1 - 0.0006 20.1 1.6 0.0056 16.9 0.0 3.3 3 0 0 3 3 3 1 ABC transporter FliD_C PF07195.7 EWM29760.1 - 0.007 15.6 1.1 0.36 10.1 0.0 3.1 3 0 0 3 3 3 1 Flagellar hook-associated protein 2 C-terminus AAA_15 PF13175.1 EWM29760.1 - 0.027 13.5 1.6 0.033 13.2 0.0 1.9 3 0 0 3 3 3 0 AAA ATPase domain NACHT PF05729.7 EWM29760.1 - 0.033 13.8 0.1 0.096 12.3 0.1 1.8 1 0 0 1 1 1 0 NACHT domain AAA_13 PF13166.1 EWM29760.1 - 0.075 11.4 0.0 0.075 11.4 0.0 4.8 4 2 0 4 4 4 0 AAA domain AAA_19 PF13245.1 EWM29760.1 - 0.075 12.7 0.4 0.3 10.8 0.1 2.1 2 0 0 2 2 1 0 Part of AAA domain Cauli_AT PF03233.8 EWM29760.1 - 4.6 6.9 8.0 15 5.2 3.7 3.0 2 1 0 2 2 2 0 Aphid transmission protein LON PF02190.11 EWM29762.1 - 8.9e-08 32.0 0.1 1.4e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain RNase_PH PF01138.16 EWM29763.1 - 2e-24 86.3 0.0 3.1e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EWM29763.1 - 0.036 13.9 0.2 1.4 8.8 0.0 2.5 1 1 1 2 2 2 0 3' exoribonuclease family, domain 2 Brix PF04427.13 EWM29765.1 - 1.3e-40 139.0 0.0 1.9e-40 138.5 0.0 1.2 1 0 0 1 1 1 1 Brix domain DUF2868 PF11067.3 EWM29765.1 - 0.0092 15.1 0.1 0.019 14.1 0.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2868) Suf PF05843.9 EWM29765.1 - 0.06 13.0 0.3 0.1 12.2 0.2 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Aminotran_4 PF01063.14 EWM29766.1 - 3.3e-15 56.2 0.0 5.7e-15 55.4 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class IV PI3_PI4_kinase PF00454.22 EWM29767.1 - 5.2e-30 104.6 0.0 1.4e-29 103.2 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Myb_DNA-binding PF00249.26 EWM29768.1 - 4.5e-11 42.6 0.1 7.6e-06 25.8 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EWM29768.1 - 5.9e-06 26.2 3.9 8.7e-05 22.5 0.1 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain S1FA PF04689.8 EWM29769.1 - 0.054 13.3 0.7 0.089 12.6 0.5 1.3 1 0 0 1 1 1 0 DNA binding protein S1FA FixQ PF05545.6 EWM29769.1 - 0.093 12.3 0.7 0.17 11.5 0.5 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ DUF843 PF05814.6 EWM29769.1 - 0.13 12.0 0.1 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) Sec7 PF01369.15 EWM29770.1 - 9.4e-59 198.2 0.1 1.6e-58 197.5 0.1 1.3 1 0 0 1 1 1 1 Sec7 domain PH PF00169.24 EWM29770.1 - 3.5e-14 52.8 0.3 2.4e-09 37.3 0.0 3.1 2 1 0 2 2 2 2 PH domain PH_11 PF15413.1 EWM29770.1 - 1e-05 25.7 0.3 0.0026 17.9 0.0 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 EWM29770.1 - 0.066 13.2 0.6 25 5.0 0.0 4.0 5 0 0 5 5 5 0 Pleckstrin homology domain PH_4 PF15404.1 EWM29770.1 - 0.076 12.5 0.2 0.34 10.4 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain PH_6 PF15406.1 EWM29770.1 - 0.11 12.5 0.1 3.4 7.7 0.2 2.4 1 1 1 2 2 2 0 Pleckstrin homology domain Helicase_C_2 PF13307.1 EWM29771.1 - 5.5e-49 166.3 0.0 1.4e-48 165.0 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 EWM29771.1 - 8.7e-44 148.9 2.3 1.6e-43 148.1 1.0 1.9 2 0 0 2 2 2 1 DEAD_2 AAA_11 PF13086.1 EWM29771.1 - 8.1e-05 22.3 3.6 0.00075 19.1 1.2 2.7 2 1 0 2 2 2 1 AAA domain ResIII PF04851.10 EWM29771.1 - 0.0012 18.6 0.0 0.23 11.2 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Ank_2 PF12796.2 EWM29772.1 - 6.2e-36 122.6 0.6 2.5e-19 69.3 0.0 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EWM29772.1 - 3e-29 99.3 0.0 2.2e-09 36.6 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 EWM29772.1 - 2e-26 91.3 0.2 9.2e-11 41.6 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EWM29772.1 - 4.1e-26 90.8 0.5 1.2e-09 38.4 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM29772.1 - 6.5e-22 75.4 0.0 3.1e-06 26.8 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Iso_dh PF00180.15 EWM29773.1 - 8.5e-78 261.7 0.0 9.9e-78 261.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Abi PF02517.11 EWM29775.1 - 1.1e-14 54.2 5.8 1.1e-14 54.2 4.0 2.7 3 1 1 4 4 4 1 CAAX protease self-immunity UPF0233 PF06781.7 EWM29775.1 - 2.6 7.7 8.7 0.2 11.3 1.1 2.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0233) Pro_isomerase PF00160.16 EWM29777.1 - 1.2e-09 38.5 0.0 2.9e-09 37.3 0.0 1.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.20 EWM29778.1 - 1.7e-69 233.8 0.0 2.7e-69 233.2 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM29778.1 - 5.5e-34 117.4 0.0 7.1e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EWM29778.1 - 2.2e-05 23.6 0.0 3.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EWM29778.1 - 0.00018 20.5 0.0 0.00027 20.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EWM29778.1 - 0.0024 17.6 0.0 0.0037 17.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EWM29778.1 - 0.023 13.5 0.0 0.035 12.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FoP_duplication PF13865.1 EWM29778.1 - 0.1 13.0 0.2 0.21 12.0 0.2 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Ras PF00071.17 EWM29779.1 - 1.3e-50 170.9 0.0 1.8e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EWM29779.1 - 3.3e-16 59.8 0.0 5.1e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EWM29779.1 - 2.1e-12 46.6 0.0 3.1e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EWM29779.1 - 0.0012 18.0 0.0 0.0018 17.4 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EWM29779.1 - 0.0095 15.8 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EWM29779.1 - 0.011 15.0 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EWM29779.1 - 0.022 14.2 0.0 0.36 10.3 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 EWM29779.1 - 0.023 14.3 0.0 0.059 12.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EWM29779.1 - 0.023 14.4 0.0 0.065 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EWM29779.1 - 0.023 14.8 0.0 0.043 13.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EWM29779.1 - 0.032 13.4 0.0 0.063 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MCM PF00493.18 EWM29779.1 - 0.059 12.1 0.0 0.092 11.5 0.0 1.2 1 0 0 1 1 1 0 MCM2/3/5 family FeoB_N PF02421.13 EWM29779.1 - 0.09 12.0 0.0 3.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.1 EWM29779.1 - 0.094 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Maf_N PF08383.6 EWM29779.1 - 0.17 11.4 0.3 0.33 10.5 0.2 1.5 1 0 0 1 1 1 0 Maf N-terminal region CmcH_NodU PF02543.10 EWM29780.1 - 1.9e-70 237.8 0.0 1.5e-69 234.8 0.0 2.1 2 0 0 2 2 2 1 Carbamoyltransferase Peptidase_M22 PF00814.20 EWM29780.1 - 0.0002 20.9 0.0 0.0015 18.1 0.0 2.0 2 0 0 2 2 2 1 Glycoprotease family zf-RING_5 PF14634.1 EWM29781.1 - 7.3e-05 22.4 18.3 0.00015 21.4 12.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain SlyX PF04102.7 EWM29781.1 - 0.00036 20.8 0.5 0.00036 20.8 0.3 2.5 3 0 0 3 3 3 1 SlyX zf-RING_2 PF13639.1 EWM29781.1 - 0.00075 19.2 18.6 0.00078 19.2 11.9 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EWM29781.1 - 0.0051 16.8 17.3 0.01 15.8 12.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EWM29781.1 - 0.0094 15.6 14.4 0.018 14.6 10.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Phlebovirus_NSM PF07246.6 EWM29781.1 - 0.032 13.4 0.8 0.049 12.7 0.5 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF1664 PF07889.7 EWM29781.1 - 0.056 13.2 0.3 0.13 12.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Amnionless PF14828.1 EWM29781.1 - 0.23 9.9 5.2 0.15 10.5 1.7 2.0 2 0 0 2 2 2 0 Amnionless Rad50_zn_hook PF04423.9 EWM29781.1 - 0.72 9.3 5.3 0.14 11.6 0.6 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif Tropomyosin_1 PF12718.2 EWM29781.1 - 0.94 9.3 13.8 0.041 13.7 3.7 2.2 2 0 0 2 2 2 0 Tropomyosin like ADIP PF11559.3 EWM29781.1 - 4.5 7.1 12.5 0.1 12.4 3.6 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DivIVA PF05103.8 EWM29781.1 - 8.5 6.4 11.3 0.37 10.8 2.6 2.3 2 1 0 2 2 2 0 DivIVA protein GATase_2 PF00310.16 EWM29782.1 - 2.3e-24 85.8 0.0 9.1e-17 60.8 0.0 2.6 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EWM29782.1 - 3.2e-16 59.4 0.0 1e-15 57.8 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EWM29782.1 - 2.1e-15 56.5 0.0 5.9e-15 55.1 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 EWM29782.1 - 8.2e-10 38.4 0.0 2e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain TPR_11 PF13414.1 EWM29783.1 - 3.9e-29 100.0 15.8 1.4e-13 50.2 3.0 4.8 3 2 2 5 5 5 4 TPR repeat TPR_1 PF00515.23 EWM29783.1 - 1.7e-21 74.8 8.9 1.7e-06 27.3 0.2 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EWM29783.1 - 9.7e-20 68.8 9.6 6.2e-06 25.7 0.4 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 EWM29783.1 - 1.7e-10 41.2 17.4 1.1e-05 25.8 1.7 4.6 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 EWM29783.1 - 1.4e-09 37.7 10.3 0.00088 19.1 1.1 5.3 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EWM29783.1 - 1.9e-07 30.7 5.0 0.19 11.9 0.2 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EWM29783.1 - 2.9e-07 29.7 7.4 0.45 10.4 0.1 6.2 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 EWM29783.1 - 6.7e-07 28.6 12.5 0.033 13.9 0.2 4.9 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 EWM29783.1 - 1.3e-05 24.9 1.7 0.39 10.5 0.0 4.0 4 1 0 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EWM29783.1 - 3.9e-05 23.4 1.2 0.036 13.9 0.1 4.3 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.1 EWM29783.1 - 0.00081 19.8 15.3 0.15 12.8 0.0 5.9 3 2 4 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 EWM29783.1 - 0.00084 19.6 8.5 0.13 12.6 1.6 4.1 2 2 1 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 EWM29783.1 - 0.0093 15.8 6.7 0.42 10.5 0.2 3.9 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain Apc3 PF12895.2 EWM29783.1 - 0.0098 16.0 11.2 0.052 13.6 2.1 3.3 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TEX12 PF15219.1 EWM29783.1 - 0.037 13.9 0.2 0.11 12.4 0.2 1.9 1 1 1 2 2 2 0 Testis-expressed 12 TPR_6 PF13174.1 EWM29783.1 - 0.073 13.5 14.6 1.1 9.8 0.3 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.1 EWM29783.1 - 0.095 12.8 8.3 12 6.1 0.0 4.3 2 1 4 6 6 6 0 Tetratricopeptide repeat DUF3856 PF12968.2 EWM29783.1 - 0.31 10.8 7.6 29 4.4 0.5 4.5 2 2 1 3 3 3 0 Domain of Unknown Function (DUF3856) tRNA_bind PF01588.15 EWM29784.1 - 4.8e-29 100.0 0.0 1.4e-27 95.3 0.0 2.3 2 0 0 2 2 2 1 Putative tRNA binding domain GST_C_3 PF14497.1 EWM29784.1 - 2.5e-07 31.0 0.0 5.4e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EWM29784.1 - 0.0054 16.6 0.0 0.019 14.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EWM29784.1 - 0.0075 16.1 0.1 0.021 14.6 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ADH_N PF08240.7 EWM29785.1 - 2.5e-29 101.1 3.0 2.5e-29 101.1 2.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EWM29785.1 - 9.2e-25 86.6 0.2 1.7e-24 85.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EWM29785.1 - 0.00012 23.0 0.0 0.00021 22.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EWM29785.1 - 0.00022 20.4 0.0 0.00036 19.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EWM29785.1 - 0.0028 17.5 0.1 0.0043 16.8 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 EWM29785.1 - 0.026 14.6 0.0 0.054 13.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MR_MLE_C PF13378.1 EWM29785.1 - 0.033 14.1 1.8 0.84 9.6 0.0 2.5 2 0 0 2 2 2 0 Enolase C-terminal domain-like NAD_binding_10 PF13460.1 EWM29785.1 - 0.043 13.8 0.0 0.065 13.2 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding DUF1449 PF07290.6 EWM29785.1 - 0.056 12.7 0.0 0.096 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) 3HCDH_N PF02737.13 EWM29785.1 - 0.088 12.4 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_N PF08240.7 EWM29786.1 - 2.5e-29 101.1 3.0 2.5e-29 101.1 2.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EWM29786.1 - 9.2e-25 86.6 0.2 1.7e-24 85.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EWM29786.1 - 0.00012 23.0 0.0 0.00021 22.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EWM29786.1 - 0.00022 20.4 0.0 0.00036 19.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EWM29786.1 - 0.0028 17.5 0.1 0.0043 16.8 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 EWM29786.1 - 0.026 14.6 0.0 0.054 13.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MR_MLE_C PF13378.1 EWM29786.1 - 0.033 14.1 1.8 0.84 9.6 0.0 2.5 2 0 0 2 2 2 0 Enolase C-terminal domain-like NAD_binding_10 PF13460.1 EWM29786.1 - 0.043 13.8 0.0 0.065 13.2 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding DUF1449 PF07290.6 EWM29786.1 - 0.056 12.7 0.0 0.096 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) 3HCDH_N PF02737.13 EWM29786.1 - 0.088 12.4 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PNP_UDP_1 PF01048.15 EWM29787.1 - 3.4e-26 91.6 0.1 4.4e-26 91.2 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Ribosomal_L5_C PF00673.16 EWM29788.1 - 1e-22 79.6 0.1 1.5e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EWM29788.1 - 9.3e-20 70.1 0.0 3.6e-19 68.2 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 Pyr_redox_2 PF07992.9 EWM29789.1 - 7.4e-23 81.4 0.1 2.6e-21 76.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EWM29789.1 - 0.0007 18.6 1.6 0.0011 17.8 0.3 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EWM29789.1 - 0.0021 16.9 1.3 1.2 7.8 0.0 2.6 2 1 1 3 3 3 2 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EWM29789.1 - 0.0027 17.4 1.6 0.26 11.0 0.1 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EWM29789.1 - 0.0061 15.4 0.1 0.66 8.7 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.9 EWM29789.1 - 0.011 14.4 0.3 0.023 13.3 0.2 1.5 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 EWM29789.1 - 0.015 15.3 0.0 0.41 10.6 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EWM29789.1 - 0.044 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EWM29789.1 - 0.11 12.9 0.4 0.11 12.9 0.3 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase PIP5K PF01504.13 EWM29790.1 - 1.5e-68 230.6 0.0 2.2e-68 230.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase EF-hand_6 PF13405.1 EWM29790.1 - 1.1e-10 40.4 1.3 0.0039 16.9 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 EWM29790.1 - 1.7e-09 36.2 1.9 0.00068 18.7 0.1 3.6 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.1 EWM29790.1 - 9.4e-09 34.2 1.8 0.0011 18.2 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EWM29790.1 - 1.2e-07 31.7 0.4 0.01 15.9 0.0 2.6 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EWM29790.1 - 3.3e-07 29.8 0.5 3.5e-05 23.3 0.0 2.6 1 1 1 2 2 2 1 EF-hand domain pair Chloroa_b-bind PF00504.16 EWM29791.1 - 2.5e-40 138.2 0.1 3.2e-40 137.9 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein ATP_sub_h PF10775.4 EWM29791.1 - 0.14 11.8 0.1 0.27 10.9 0.1 1.4 1 0 0 1 1 1 0 ATP synthase complex subunit h Glyco_hydro_31 PF01055.21 EWM29793.1 - 1.1e-155 518.8 2.5 1.3e-155 518.5 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EWM29793.1 - 4.4e-20 71.3 0.0 9.4e-20 70.2 0.0 1.6 1 0 0 1 1 1 1 Galactose mutarotase-like PH PF00169.24 EWM29794.1 - 4.7e-09 36.3 0.3 0.001 19.2 0.0 3.0 2 1 0 2 2 2 2 PH domain PH_11 PF15413.1 EWM29794.1 - 0.0057 16.8 3.6 2.2 8.5 0.1 4.3 3 1 0 3 3 3 1 Pleckstrin homology domain Biotin_lipoyl PF00364.17 EWM29794.1 - 0.15 11.6 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Biotin-requiring enzyme WD40 PF00400.27 EWM29795.1 - 1.9e-26 90.9 1.9 2.6e-07 30.2 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat GTP_EFTU PF00009.22 EWM29796.1 - 1.3e-52 177.9 0.1 2.2e-52 177.2 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EWM29796.1 - 6.2e-20 70.8 0.0 1.3e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EWM29796.1 - 2.1e-08 34.1 0.9 6.5e-08 32.5 0.2 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EWM29796.1 - 2.4e-06 27.4 0.2 4.3e-06 26.6 0.2 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.13 EWM29796.1 - 1.9e-05 23.8 0.0 7.1e-05 21.9 0.1 1.7 2 0 0 2 2 2 1 Septin Miro PF08477.8 EWM29796.1 - 0.00011 22.6 0.1 0.00022 21.7 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 EWM29796.1 - 0.00029 20.1 0.1 0.0082 15.4 0.0 3.0 2 1 0 2 2 2 1 Ferrous iron transport protein B EFG_II PF14492.1 EWM29796.1 - 0.00076 19.2 0.1 0.002 17.9 0.1 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II Dynamin_N PF00350.18 EWM29796.1 - 0.0067 16.2 0.0 0.1 12.4 0.0 2.0 1 1 1 2 2 2 1 Dynamin family SRPRB PF09439.5 EWM29796.1 - 0.02 14.1 0.1 0.12 11.6 0.0 2.2 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit Arf PF00025.16 EWM29796.1 - 0.022 13.9 0.0 0.054 12.7 0.0 1.6 2 0 0 2 2 2 0 ADP-ribosylation factor family N6-adenineMlase PF10237.4 EWM29797.1 - 4e-37 127.3 0.0 4.7e-37 127.1 0.0 1.0 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase PLA2_B PF01735.13 EWM29798.1 - 2.4e-22 78.7 5.1 6.8e-11 41.0 0.0 3.5 4 0 0 4 4 4 3 Lysophospholipase catalytic domain SCP2 PF02036.12 EWM29799.1 - 1.1e-45 154.1 3.1 2.4e-22 79.1 0.1 2.1 2 0 0 2 2 2 2 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EWM29799.1 - 9.5e-13 48.2 1.1 4.5e-06 26.6 0.0 2.2 1 1 0 2 2 2 2 Alkyl sulfatase C-terminal SCP2_2 PF13530.1 EWM29799.1 - 2.5e-07 30.3 0.0 0.0017 17.7 0.0 2.2 2 0 0 2 2 2 2 Sterol carrier protein domain DUF4098 PF13345.1 EWM29799.1 - 0.066 13.1 0.9 4.6 7.2 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4098) MTS PF05175.9 EWM29799.1 - 0.076 12.3 0.6 0.79 9.0 0.0 2.2 1 1 0 2 2 2 0 Methyltransferase small domain DUF1754 PF08555.5 EWM29799.1 - 0.26 11.9 3.1 1.3 9.6 0.7 2.3 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Elong-fact-P_C PF09285.6 EWM29800.1 - 3.2e-17 61.6 0.1 6.6e-17 60.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP_N PF08207.7 EWM29800.1 - 1.7e-16 59.7 0.2 3.5e-16 58.8 0.1 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain EFP PF01132.15 EWM29800.1 - 4.7e-14 51.7 0.4 8.7e-14 50.9 0.3 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain Hist_deacetyl PF00850.14 EWM29801.1 - 2.7e-78 263.4 0.3 3.3e-78 263.1 0.2 1.1 1 0 0 1 1 1 1 Histone deacetylase domain RRM_1 PF00076.17 EWM29802.1 - 1e-23 82.7 0.1 3e-11 42.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM29802.1 - 8.9e-17 60.6 0.0 9e-12 44.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM29802.1 - 1.1e-15 57.2 0.2 8.6e-08 32.0 0.1 2.4 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) APG6 PF04111.7 EWM29803.1 - 0.00099 18.2 17.8 0.00099 18.2 12.4 6.0 4 1 1 6 6 6 4 Autophagy protein Apg6 DASH_Dam1 PF08653.5 EWM29803.1 - 1.1 9.0 6.3 6 6.7 0.1 4.0 4 0 0 4 4 4 0 DASH complex subunit Dam1 Guanylate_kin PF00625.16 EWM29804.1 - 1.1e-54 184.6 0.0 1.5e-54 184.2 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.1 EWM29804.1 - 9.9e-07 28.7 0.0 1.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EWM29804.1 - 0.00024 20.3 0.0 0.00043 19.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EWM29804.1 - 0.00031 21.5 0.0 0.0006 20.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EWM29804.1 - 0.0023 18.2 0.3 0.0056 16.9 0.2 1.7 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 EWM29804.1 - 0.0031 17.2 0.0 0.0064 16.2 0.0 1.5 1 0 0 1 1 1 1 NTPase AAA_22 PF13401.1 EWM29804.1 - 0.007 16.5 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EWM29804.1 - 0.014 15.3 0.2 0.022 14.7 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 EWM29804.1 - 0.027 14.3 0.0 0.065 13.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EWM29804.1 - 0.044 14.0 0.0 0.07 13.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 EWM29804.1 - 0.048 12.7 0.0 4.3 6.3 0.0 2.5 3 0 0 3 3 3 0 Zeta toxin MMR_HSR1 PF01926.18 EWM29804.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 EWM29804.1 - 0.084 12.4 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 EWM29804.1 - 0.13 11.9 0.0 0.32 10.6 0.0 1.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Proteasome_A_N PF10584.4 EWM29805.1 - 6.5e-08 31.7 0.2 1.1e-07 31.0 0.2 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Acyl-CoA_dh_1 PF00441.19 EWM29806.1 - 1.3e-34 119.4 6.2 1.9e-34 118.9 4.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EWM29806.1 - 1.8e-16 59.3 0.0 3.8e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EWM29806.1 - 2.8e-11 43.7 6.2 5.2e-11 42.9 4.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EWM29806.1 - 3.3e-10 40.5 0.7 8.1e-10 39.2 0.0 2.0 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain GUN4 PF05419.7 EWM29807.1 - 1.2e-30 106.0 0.0 1.6e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 GUN4-like Peptidase_M16_C PF05193.16 EWM29808.1 - 2.1e-08 34.0 0.0 6.7e-08 32.4 0.0 1.9 1 1 0 1 1 1 1 Peptidase M16 inactive domain NAC PF01849.13 EWM29809.1 - 1.1e-21 76.1 0.2 2e-21 75.2 0.1 1.5 1 0 0 1 1 1 1 NAC domain TetR_C_7 PF14246.1 EWM29809.1 - 0.099 12.8 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal region Sugar_tr PF00083.19 EWM29810.1 - 4.4e-101 338.6 27.4 4e-79 266.2 10.0 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EWM29810.1 - 4.4e-24 84.8 50.7 1.8e-20 72.9 14.0 3.3 2 2 1 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.8 EWM29810.1 - 4.3e-08 31.8 3.7 4.3e-08 31.8 2.6 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EWM29810.1 - 0.8 7.7 13.4 0.012 13.7 4.0 1.8 2 0 0 2 2 2 0 Transmembrane secretion effector Abhydrolase_2 PF02230.11 EWM29812.1 - 3.4e-30 105.0 0.0 6.2e-30 104.2 0.0 1.5 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EWM29812.1 - 1.8e-12 47.2 0.1 3.1e-12 46.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EWM29812.1 - 9.8e-09 35.4 0.4 2.9e-08 33.8 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EWM29812.1 - 8.5e-07 28.4 0.1 0.002 17.3 0.0 2.8 2 1 1 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EWM29812.1 - 0.00012 21.7 0.1 0.00035 20.2 0.0 1.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EWM29812.1 - 0.00015 21.3 0.0 0.00036 20.1 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 EWM29812.1 - 0.00066 19.5 0.0 0.0023 17.7 0.0 1.9 1 0 0 1 1 1 1 TAP-like protein DLH PF01738.13 EWM29812.1 - 0.0024 17.1 0.0 0.005 16.1 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Esterase_phd PF10503.4 EWM29812.1 - 0.0026 17.0 0.0 0.01 15.1 0.0 1.9 1 1 1 2 2 2 1 Esterase PHB depolymerase DUF4349 PF14257.1 EWM29812.1 - 0.061 12.5 1.0 0.11 11.6 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF2048 PF09752.4 EWM29812.1 - 0.1 11.4 0.8 0.21 10.4 0.5 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) AXE1 PF05448.7 EWM29812.1 - 0.15 10.5 0.0 0.22 9.9 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Transaldolase PF00923.14 EWM29813.1 - 1.2e-196 651.3 0.0 3.1e-98 328.4 0.0 2.0 2 0 0 2 2 2 2 Transaldolase CG-1 PF03859.11 EWM29813.1 - 0.002 17.6 1.5 1.8 8.1 0.1 2.3 2 0 0 2 2 2 2 CG-1 domain FlpD PF02662.11 EWM29813.1 - 0.015 14.9 1.9 8 6.1 0.0 3.7 4 0 0 4 4 4 0 Methyl-viologen-reducing hydrogenase, delta subunit Phage_term_smal PF05944.7 EWM29813.1 - 0.024 14.2 0.0 0.83 9.3 0.0 2.4 2 0 0 2 2 2 0 Phage small terminase subunit DnaB_2 PF07261.6 EWM29813.1 - 0.026 14.1 0.0 15 5.3 0.0 3.0 2 0 0 2 2 2 0 Replication initiation and membrane attachment HTH_28 PF13518.1 EWM29813.1 - 0.037 14.0 0.3 19 5.4 0.0 2.9 2 0 0 2 2 2 0 Helix-turn-helix domain RbcS PF12338.3 EWM29813.1 - 0.084 12.6 5.8 4.4 7.1 0.4 2.7 2 0 0 2 2 2 0 Ribulose-1,5-bisphosphate carboxylase small subunit GIDA_assoc_3 PF13932.1 EWM29813.1 - 0.099 12.7 0.0 27 4.8 0.0 2.7 2 0 0 2 2 2 0 GidA associated domain 3 Utp21 PF04192.7 EWM29814.1 - 2e-37 128.5 0.6 1.4e-36 125.7 0.4 2.0 1 1 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EWM29814.1 - 9.6e-35 117.2 0.7 2.7e-09 36.5 0.0 8.4 8 0 0 8 8 8 6 WD domain, G-beta repeat Hira PF07569.6 EWM29814.1 - 0.0037 16.4 0.1 0.17 11.0 0.0 3.6 5 0 0 5 5 5 1 TUP1-like enhancer of split Cytochrom_D1 PF02239.11 EWM29814.1 - 0.035 12.3 0.0 0.23 9.7 0.0 2.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain Nup160 PF11715.3 EWM29814.1 - 0.048 11.7 1.4 0.21 9.6 0.1 2.4 3 1 1 4 4 4 0 Nucleoporin Nup120/160 Sulfatase PF00884.18 EWM29815.1 - 9.9e-47 159.6 0.0 1.5e-46 159.0 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EWM29815.1 - 1.4e-05 24.5 0.0 2.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Peptidase_S49 PF01343.13 EWM29816.1 - 3.7e-23 82.0 0.0 5.3e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family S49 Thioesterase PF00975.15 EWM29817.1 - 9.6e-31 107.7 0.0 1.4e-30 107.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EWM29817.1 - 8.4e-11 42.1 0.0 1.7e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM29817.1 - 1.6e-06 27.9 0.0 2.8e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EWM29817.1 - 0.012 15.1 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) FSH1 PF03959.8 EWM29817.1 - 0.026 13.9 0.0 0.039 13.3 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_8 PF06259.7 EWM29817.1 - 0.032 13.7 0.1 0.81 9.1 0.0 2.3 1 1 1 2 2 2 0 Alpha/beta hydrolase Cyclin_N PF00134.18 EWM29818.1 - 8.1e-09 35.1 0.0 0.0032 17.0 0.0 3.2 3 0 0 3 3 3 3 Cyclin, N-terminal domain Cyclin_C PF02984.14 EWM29818.1 - 0.0033 17.3 0.0 0.076 12.9 0.0 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.14 EWM29818.1 - 0.068 12.9 0.1 13 5.6 0.0 2.5 2 0 0 2 2 2 0 Transcription factor TFIIB repeat HAD_2 PF13419.1 EWM29820.1 - 1.3e-23 84.1 0.0 1.6e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EWM29820.1 - 5.9e-10 39.9 0.0 2.7e-08 34.5 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EWM29820.1 - 4.8e-07 29.4 0.0 7.4e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EWM29820.1 - 4.5e-06 26.9 0.0 9.1e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EWM29820.1 - 7.7e-05 22.5 0.0 0.0093 15.8 0.0 2.5 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase ICMT PF04140.9 EWM29821.1 - 3.7e-29 100.7 0.5 7.2e-29 99.8 0.4 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EWM29821.1 - 7.2e-14 51.7 0.4 7.2e-14 51.7 0.3 2.4 2 1 1 3 3 3 1 Phospholipid methyltransferase PP2C PF00481.16 EWM29822.1 - 4.4e-44 150.7 0.0 1.2e-43 149.3 0.0 1.6 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.7 EWM29822.1 - 0.00018 21.2 0.1 0.024 14.3 0.0 3.0 2 1 1 3 3 3 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EWM29822.1 - 0.027 13.9 0.1 0.12 11.7 0.1 2.1 1 1 0 1 1 1 0 Protein phosphatase 2C PPR_2 PF13041.1 EWM29823.1 - 2.1e-35 120.4 0.0 6.9e-11 41.9 0.0 12.7 12 2 3 15 15 15 5 PPR repeat family PPR PF01535.15 EWM29823.1 - 3.6e-32 108.0 5.5 7.6e-07 28.6 0.0 14.0 16 0 0 16 16 16 6 PPR repeat PPR_3 PF13812.1 EWM29823.1 - 1.4e-23 81.1 26.2 0.00027 20.9 0.0 16.0 18 1 0 18 18 18 5 Pentatricopeptide repeat domain PPR_1 PF12854.2 EWM29823.1 - 2.4e-14 52.5 5.4 0.00027 20.3 0.0 8.5 10 0 0 10 10 10 2 PPR repeat TPR_14 PF13428.1 EWM29823.1 - 1.1 10.1 36.7 8.1 7.3 0.1 11.7 12 2 2 14 14 14 0 Tetratricopeptide repeat TPR_17 PF13431.1 EWM29824.1 - 2.3e-08 33.6 0.0 0.004 17.2 0.0 3.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EWM29824.1 - 4.1e-08 32.5 7.9 0.072 13.0 0.0 5.2 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 EWM29824.1 - 1.2e-07 31.9 8.9 0.0013 19.0 0.1 4.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EWM29824.1 - 1.3e-07 31.1 9.2 5e-06 26.0 0.1 3.7 4 0 0 4 4 4 2 TPR repeat TPR_16 PF13432.1 EWM29824.1 - 1.4e-06 28.8 11.4 8.1e-05 23.1 0.4 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EWM29824.1 - 1.4e-06 27.6 2.0 1 9.1 0.0 4.6 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EWM29824.1 - 5.1e-06 26.6 10.4 0.062 13.9 0.5 5.2 4 2 2 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EWM29824.1 - 2.3e-05 23.8 0.4 1.5 8.7 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.1 EWM29824.1 - 0.00087 18.4 6.1 0.27 10.2 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EWM29824.1 - 0.0012 18.4 1.0 13 5.8 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EWM29824.1 - 0.0028 17.5 8.5 0.053 13.4 0.1 4.5 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EWM29824.1 - 0.39 11.2 7.8 42 4.8 0.2 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_60s PF00428.14 EWM29825.1 - 0.0049 17.2 10.3 0.0049 17.2 7.2 1.9 2 0 0 2 2 2 1 60s Acidic ribosomal protein PSK_trans_fac PF07704.6 EWM29825.1 - 0.031 14.9 6.0 0.11 13.1 4.2 2.0 1 0 0 1 1 1 0 Rv0623-like transcription factor DAGK_acc PF00609.14 EWM29826.1 - 2.3e-52 177.3 0.1 5.3e-34 117.6 0.0 2.2 2 0 0 2 2 2 2 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 EWM29826.1 - 2.2e-28 98.2 0.0 4.5e-28 97.2 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF3395 PF11875.3 EWM29826.1 - 0.0029 17.2 1.1 0.0057 16.3 0.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) TT_ORF1 PF02956.9 EWM29826.1 - 0.6 8.4 5.0 0.88 7.9 3.5 1.1 1 0 0 1 1 1 0 TT viral orf 1 Cas_Csy4 PF09618.5 EWM29826.1 - 0.76 9.5 5.5 1.6 8.5 3.8 1.5 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) Baculo_PP31 PF05311.6 EWM29826.1 - 6.8 5.8 5.9 11 5.1 4.1 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Methyltransf_26 PF13659.1 EWM29827.1 - 0.0056 16.6 0.0 0.0084 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM29827.1 - 0.013 16.1 0.0 0.019 15.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain LSM PF01423.17 EWM29828.1 - 3.4e-14 52.1 0.1 4.8e-14 51.6 0.1 1.2 1 0 0 1 1 1 1 LSM domain S-methyl_trans PF02574.11 EWM29829.1 - 3.3e-42 144.8 0.4 1.3e-41 142.8 0.2 1.9 1 1 0 1 1 1 1 Homocysteine S-methyltransferase S-methyl_trans PF02574.11 EWM29830.1 - 4.8e-56 190.2 0.6 7.7e-29 100.9 0.1 2.7 2 1 0 2 2 2 2 Homocysteine S-methyltransferase Sugar_tr PF00083.19 EWM29831.1 - 3.6e-38 131.2 20.6 2.2e-26 92.4 3.2 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EWM29831.1 - 4.3e-29 101.3 43.6 1.1e-18 67.0 15.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EWM29831.1 - 0.001 17.5 22.4 0.024 13.0 1.4 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein Patatin PF01734.17 EWM29831.1 - 0.025 14.4 1.9 0.039 13.8 0.4 1.9 2 1 0 2 2 2 0 Patatin-like phospholipase mTERF PF02536.9 EWM29832.1 - 1.1e-11 43.8 0.0 5.9e-09 34.9 0.0 2.7 3 0 0 3 3 3 2 mTERF DUF3650 PF12368.3 EWM29832.1 - 2.1 7.9 4.2 5.1 6.6 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) ELO PF01151.13 EWM29833.1 - 7.1e-62 208.9 10.5 8.5e-62 208.6 7.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family UreF PF01730.11 EWM29835.1 - 0.015 15.4 3.2 0.075 13.1 0.0 2.7 3 0 0 3 3 3 0 UreF PMBR PF09373.5 EWM29835.1 - 0.1 12.5 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 Pseudomurein-binding repeat Alkyl_sulf_dimr PF14863.1 EWM29836.1 - 4.8e-34 117.5 0.0 6.9e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.22 EWM29836.1 - 1.8e-18 66.8 2.3 9.8e-18 64.4 1.6 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EWM29836.1 - 0.00011 21.8 0.1 0.00052 19.6 0.1 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Alkyl_sulf_C PF14864.1 EWM29836.1 - 0.00022 21.1 0.0 0.00038 20.4 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2 PF02036.12 EWM29836.1 - 0.086 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 SCP-2 sterol transfer family Aminotran_1_2 PF00155.16 EWM29837.1 - 1.1e-62 212.0 0.0 1.3e-62 211.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EWM29837.1 - 1.8e-06 27.2 0.0 2.8e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EWM29837.1 - 0.0054 15.5 0.0 0.0091 14.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EWM29837.1 - 0.006 14.9 0.0 0.14 10.3 0.0 2.2 1 1 1 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.15 EWM29837.1 - 0.031 12.8 0.0 0.054 12.0 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Bac_surface_Ag PF01103.18 EWM29838.1 - 6.3e-38 131.0 0.0 9e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Surface antigen Dak1 PF02733.12 EWM29839.1 - 7.7e-107 356.6 0.6 1.1e-106 356.1 0.4 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EWM29839.1 - 8.5e-41 139.5 1.4 1.6e-40 138.6 1.0 1.5 1 0 0 1 1 1 1 DAK2 domain DMRL_synthase PF00885.14 EWM29840.1 - 6.2e-11 42.1 2.1 1.6e-10 40.8 1.5 1.7 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase DUF1517 PF07466.6 EWM29841.1 - 1e-28 100.1 0.0 1.4e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) DUF1147 PF06615.6 EWM29841.1 - 0.13 12.0 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) DUF1517 PF07466.6 EWM29842.1 - 1.5e-28 99.6 0.0 2.3e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) DUF1147 PF06615.6 EWM29842.1 - 0.14 12.0 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) Acyl_transf_3 PF01757.17 EWM29843.1 - 4.4e-15 55.3 39.5 9.4e-15 54.2 27.4 1.5 1 0 0 1 1 1 1 Acyltransferase family DUF4381 PF14316.1 EWM29843.1 - 0.029 14.4 0.3 0.089 12.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) adh_short PF00106.20 EWM29844.1 - 4.5e-18 65.7 0.0 6.5e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EWM29844.1 - 6.6e-09 35.6 0.3 1.9e-08 34.2 0.0 1.7 1 1 1 2 2 2 1 KR domain adh_short_C2 PF13561.1 EWM29844.1 - 2.5e-06 27.4 0.0 6.1e-06 26.1 0.0 1.6 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EWM29844.1 - 9.8e-06 25.1 0.0 1.3e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EWM29844.1 - 0.0017 18.3 0.3 0.028 14.4 0.2 2.2 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EWM29844.1 - 0.067 12.0 0.1 0.21 10.4 0.0 1.9 2 1 0 2 2 2 0 RmlD substrate binding domain NmrA PF05368.8 EWM29844.1 - 0.079 12.1 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family 3HCDH_N PF02737.13 EWM29844.1 - 0.14 11.8 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Opy2 PF09463.5 EWM29844.1 - 0.7 10.0 3.5 0.33 11.0 0.7 1.7 2 0 0 2 2 2 0 Opy2 protein Myosin_head PF00063.16 EWM29845.1 - 5.4e-190 632.8 0.0 7.7e-190 632.3 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.22 EWM29845.1 - 1.8e-23 79.8 140.0 0.0039 16.6 3.4 17.7 17 0 0 17 17 17 14 IQ calmodulin-binding motif Ank_4 PF13637.1 EWM29845.1 - 2.2e-14 53.4 3.9 0.00014 22.3 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EWM29845.1 - 8e-13 48.5 2.3 7.8e-07 29.3 0.1 3.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EWM29845.1 - 3.3e-12 46.2 7.2 0.0013 18.9 0.0 5.9 6 0 0 6 6 5 3 Ankyrin repeats (many copies) Aida_C2 PF14186.1 EWM29845.1 - 3.9e-10 39.1 0.0 1.1e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 Cytoskeletal adhesion PH PF00169.24 EWM29845.1 - 1.1e-08 35.2 0.1 2.7e-08 33.9 0.1 1.8 1 0 0 1 1 1 1 PH domain Ank PF00023.25 EWM29845.1 - 2.5e-08 33.3 6.8 0.11 12.3 0.0 5.5 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.1 EWM29845.1 - 2.7e-05 24.0 4.9 1.4 9.4 0.0 5.4 5 0 0 5 5 5 2 Ankyrin repeat PH_11 PF15413.1 EWM29845.1 - 4.7e-05 23.6 0.1 0.00017 21.8 0.0 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain AAA_22 PF13401.1 EWM29845.1 - 0.031 14.4 1.1 0.064 13.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain UQ_con PF00179.21 EWM29846.1 - 4.9e-42 142.6 0.0 5.5e-42 142.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EWM29846.1 - 0.071 13.0 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 RWD domain DEAD PF00270.24 EWM29847.1 - 6.5e-38 129.8 0.0 1.3e-37 128.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EWM29847.1 - 5.2e-24 83.8 0.0 1.1e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EWM29847.1 - 0.00034 20.4 0.0 0.00059 19.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF608 PF04685.8 EWM29848.1 - 4e-130 433.7 6.5 4.1e-118 394.2 0.6 2.2 1 1 0 2 2 2 2 Protein of unknown function, DUF608 GBA2_N PF12215.3 EWM29848.1 - 3.2e-71 239.9 0.0 6.7e-59 199.4 0.0 2.2 2 0 0 2 2 2 2 beta-Glucocerebrosidase 2 N terminal MFS_2 PF13347.1 EWM29849.1 - 5.3e-16 58.0 18.7 5.3e-16 58.0 13.0 1.8 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_1 PF07690.11 EWM29849.1 - 9.1e-09 34.4 19.0 9.1e-09 34.4 13.2 2.3 2 1 1 3 3 3 1 Major Facilitator Superfamily tRNA-synt_1g PF09334.6 EWM29850.1 - 1.8e-128 428.5 0.2 1e-126 422.7 0.1 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EWM29850.1 - 1.7e-27 95.6 1.0 5.1e-13 47.9 0.0 3.8 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EWM29850.1 - 1.8e-12 47.0 0.0 6.4e-07 28.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Cyclin_N PF00134.18 EWM29851.1 - 8.2e-06 25.4 0.0 2e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 Cyclin, N-terminal domain Peptidase_M15_2 PF05951.8 EWM29852.1 - 0.054 12.9 0.3 0.077 12.4 0.2 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) DUF2533 PF10752.4 EWM29852.1 - 0.6 10.4 4.8 1.3 9.3 3.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2533) DUF2462 PF09495.5 EWM29852.1 - 0.92 10.2 16.3 0.21 12.3 8.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2462) DUF1151 PF06625.6 EWM29852.1 - 3 7.5 9.8 0.48 10.1 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) PseudoU_synth_2 PF00849.17 EWM29853.1 - 4e-28 98.2 0.0 5.3e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase YccV-like PF08755.6 EWM29854.1 - 3.4e-24 84.6 0.0 1.9e-14 53.3 0.0 2.5 2 0 0 2 2 2 2 Hemimethylated DNA-binding protein YccV like Complex1_LYR PF05347.10 EWM29854.1 - 0.038 13.7 0.2 0.038 13.7 0.2 3.8 3 1 0 3 3 3 0 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EWM29854.1 - 1.6 8.9 9.6 0.48 10.6 0.4 3.7 3 1 0 3 3 3 0 Complex1_LYR-like COBRA1 PF06209.8 EWM29855.1 - 2e-09 36.6 0.0 7.1e-05 21.5 0.0 2.3 2 0 0 2 2 2 2 Cofactor of BRCA1 (COBRA1) Bromodomain PF00439.20 EWM29855.1 - 2.1e-09 37.1 0.0 4.1e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Bromodomain RNA_pol_Rbc25 PF08292.7 EWM29856.1 - 6.8e-32 110.2 0.0 2.5e-31 108.3 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EWM29856.1 - 3.6e-14 52.6 0.1 5.9e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EWM29856.1 - 0.12 12.5 0.2 0.27 11.3 0.0 1.7 2 0 0 2 2 2 0 S1 RNA binding domain HORMA PF02301.13 EWM29857.1 - 7.5e-41 139.9 0.1 8.6e-41 139.7 0.1 1.0 1 0 0 1 1 1 1 HORMA domain ATG13 PF10033.4 EWM29857.1 - 0.00016 21.1 0.1 0.0018 17.7 0.1 2.2 2 0 0 2 2 2 1 Autophagy-related protein 13 DUF1843 PF08898.5 EWM29857.1 - 0.053 13.5 0.4 0.27 11.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) zf-DNL PF05180.7 EWM29858.1 - 6.2e-13 48.2 1.0 1.2e-12 47.2 0.7 1.6 1 1 0 1 1 1 1 DNL zinc finger DnaJ_CXXCXGXG PF00684.14 EWM29858.1 - 0.16 12.0 3.5 0.95 9.5 0.0 2.6 2 0 0 2 2 2 0 DnaJ central domain URO-D PF01208.12 EWM29859.1 - 2e-105 352.5 0.0 2.4e-105 352.2 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Chloroa_b-bind PF00504.16 EWM29860.1 - 3.9e-29 101.9 0.0 4.8e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein FA_hydroxylase PF04116.8 EWM29861.1 - 8.1e-15 55.2 15.0 8.1e-15 55.2 10.4 2.6 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Clathrin PF00637.15 EWM29862.1 - 1.7e-07 30.9 0.0 4e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Region in Clathrin and VPS WD40 PF00400.27 EWM29862.1 - 0.0051 16.6 0.6 2 8.4 0.1 3.6 3 0 0 3 3 3 1 WD domain, G-beta repeat zf-rbx1 PF12678.2 EWM29862.1 - 0.088 12.9 0.2 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger Aminotran_5 PF00266.14 EWM29863.1 - 1.1e-16 60.5 0.0 1.4e-14 53.6 0.0 2.3 3 0 0 3 3 3 2 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EWM29863.1 - 0.031 13.3 0.5 0.14 11.1 0.2 2.2 3 0 0 3 3 3 0 DegT/DnrJ/EryC1/StrS aminotransferase family TM140 PF14985.1 EWM29863.1 - 0.12 12.0 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 TM140 protein family A_deaminase PF00962.17 EWM29864.1 - 2.3e-47 161.5 0.0 2.1e-44 151.7 0.0 2.2 1 1 0 1 1 1 1 Adenosine/AMP deaminase Methyltransf_11 PF08241.7 EWM29865.1 - 6.1e-23 81.1 0.0 9.8e-23 80.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM29865.1 - 2.8e-15 56.3 0.0 4.3e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM29865.1 - 6.8e-11 41.9 0.0 1e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM29865.1 - 1.1e-09 38.6 0.0 1.9e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EWM29865.1 - 1.7e-09 37.1 0.0 2.4e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EWM29865.1 - 5.9e-09 36.2 0.0 1.1e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM29865.1 - 2e-08 34.8 0.0 4e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EWM29865.1 - 1.9e-05 24.6 0.1 5.2e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain TehB PF03848.9 EWM29865.1 - 0.0021 17.2 0.0 0.0032 16.6 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_29 PF03141.11 EWM29865.1 - 0.0028 16.0 0.0 0.0038 15.6 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MetW PF07021.7 EWM29865.1 - 0.012 14.9 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.10 EWM29865.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Acyltransferase PF01553.16 EWM29867.1 - 2.2e-14 53.0 0.0 9.5e-14 50.9 0.0 2.0 1 1 0 1 1 1 1 Acyltransferase HlyIII PF03006.15 EWM29868.1 - 6.2e-37 127.1 25.4 8.3e-37 126.7 17.6 1.2 1 0 0 1 1 1 1 Haemolysin-III related LRR_6 PF13516.1 EWM29868.1 - 3.1e-05 23.6 2.5 5.5 7.3 0.3 4.7 4 0 0 4 4 4 3 Leucine Rich repeat LRR_4 PF12799.2 EWM29868.1 - 0.0094 15.5 0.1 0.62 9.7 0.0 3.2 2 1 2 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EWM29868.1 - 0.15 11.8 2.0 0.27 10.9 0.0 2.4 2 1 1 3 3 3 0 Leucine rich repeat Fer2 PF00111.22 EWM29870.1 - 0.00021 20.9 0.2 0.00032 20.4 0.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.1 EWM29870.1 - 0.012 15.3 0.1 0.016 15.0 0.1 1.2 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain PIG-F PF06699.6 EWM29871.1 - 3.9e-21 75.8 7.8 6.8e-21 75.0 5.0 1.5 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F Pyr_redox_2 PF07992.9 EWM29872.1 - 1.3e-10 41.5 0.0 2.1e-10 40.7 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EWM29872.1 - 0.03 12.9 0.4 0.3 9.6 0.0 2.5 3 0 0 3 3 3 0 Tryptophan halogenase DAO PF01266.19 EWM29872.1 - 0.041 12.7 1.9 0.34 9.7 0.6 2.4 2 1 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EWM29872.1 - 0.059 13.4 0.3 3 7.8 0.2 2.3 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EWM29872.1 - 0.14 11.9 0.0 9 6.0 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Ank_2 PF12796.2 EWM29874.1 - 3.4e-21 75.3 0.0 4e-09 36.6 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EWM29874.1 - 1e-17 64.1 0.1 4.4e-08 33.4 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EWM29874.1 - 2.4e-17 62.5 0.8 6e-07 29.5 0.0 3.5 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EWM29874.1 - 4.8e-17 60.8 1.3 8.3e-06 25.3 0.1 4.4 3 2 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 EWM29874.1 - 1.5e-09 37.1 0.3 0.01 16.0 0.1 3.9 3 1 0 3 3 3 3 Ankyrin repeat FAST_1 PF06743.10 EWM29875.1 - 0.00016 21.3 0.4 8 6.2 0.0 4.8 5 1 1 6 6 6 3 FAST kinase-like protein, subdomain 1 RAP PF08373.5 EWM29875.1 - 0.2 11.4 0.0 0.47 10.2 0.0 1.7 1 0 0 1 1 1 0 RAP domain Lactamase_B PF00753.22 EWM29876.1 - 2e-23 83.0 0.0 2.9e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EWM29876.1 - 0.0092 15.5 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF442 PF04273.8 EWM29876.1 - 0.014 15.2 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Putative phosphatase (DUF442) TraB PF01963.12 EWM29877.1 - 1.1e-23 84.0 0.2 2.4e-14 53.3 0.2 2.3 2 1 0 2 2 2 2 TraB family FTZ PF03867.9 EWM29877.1 - 0.43 9.7 3.6 0.16 11.1 0.4 1.7 2 0 0 2 2 2 0 Fushi tarazu (FTZ), N-terminal region WD40 PF00400.27 EWM29878.1 - 0.0011 18.7 2.7 2.5 8.1 0.2 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat Nup160 PF11715.3 EWM29878.1 - 0.012 13.8 0.0 0.018 13.1 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Cyt-b5 PF00173.23 EWM29879.1 - 3.2e-12 46.0 0.0 5.9e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Mmp37 PF09139.6 EWM29880.1 - 8.1e-97 324.1 0.0 1e-96 323.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 Ribosomal_S4e PF00900.15 EWM29882.1 - 1.2e-22 79.3 2.0 1.2e-22 79.2 0.1 2.0 3 0 0 3 3 3 1 Ribosomal family S4e RS4NT PF08071.7 EWM29882.1 - 3.2e-20 71.6 4.6 6.5e-20 70.7 3.2 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 EWM29882.1 - 2e-09 36.7 0.0 3.7e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EWM29882.1 - 7.8e-06 25.4 1.7 4.1e-05 23.1 0.0 2.9 3 0 0 3 3 3 1 KOW motif PepSY PF03413.14 EWM29882.1 - 0.16 12.6 0.0 35 5.1 0.0 2.5 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain zf-HC5HC2H_2 PF13832.1 EWM29883.1 - 3.1e-18 65.7 2.3 4.8e-18 65.1 1.6 1.3 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EWM29883.1 - 8e-11 41.9 1.7 4e-10 39.6 0.4 2.2 2 0 0 2 2 2 1 PHD-like zinc-binding domain PHD_2 PF13831.1 EWM29883.1 - 8.1 5.8 9.5 0.83 9.0 0.7 2.7 2 0 0 2 2 2 0 PHD-finger Metallophos PF00149.23 EWM29884.1 - 3.3e-16 59.2 0.0 2.7e-14 53.0 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Mre11_DNA_bind PF04152.9 EWM29884.1 - 1.6e-07 31.3 0.0 2.4e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain DNA_primase_lrg PF04104.9 EWM29885.1 - 5.3e-71 238.9 0.0 8.3e-71 238.2 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Phosphodiest PF01663.17 EWM29886.1 - 4.7e-10 39.3 0.1 2.8e-09 36.7 0.0 2.0 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Methyltransf_21 PF05050.7 EWM29888.1 - 1.7e-14 54.0 0.0 2.5e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Voltage_CLC PF00654.15 EWM29889.1 - 7e-71 239.1 22.6 7e-71 239.1 15.7 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EWM29889.1 - 0.00059 19.5 0.0 0.25 11.1 0.0 2.6 2 0 0 2 2 2 2 CBS domain UEV PF05743.8 EWM29890.1 - 7.5e-35 119.2 0.0 1.1e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 UEV domain UQ_con PF00179.21 EWM29890.1 - 2.8e-06 26.8 0.1 4.7e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF288 PF03385.12 EWM29892.1 - 1.3e-16 60.0 0.0 2.2e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF288 Glyco_tranf_2_4 PF13704.1 EWM29892.1 - 9.6e-08 32.2 0.0 2.7e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 CDK2AP PF09806.4 EWM29893.1 - 1.4 9.1 9.3 0.79 9.9 3.2 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein CDK2AP PF09806.4 EWM29894.1 - 0.26 11.4 5.7 0.25 11.5 1.3 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Fer2 PF00111.22 EWM29895.1 - 1.5e-08 34.2 0.5 3.8e-08 32.9 0.4 1.6 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FAA_hydrolase PF01557.13 EWM29896.1 - 3.7e-59 199.8 0.0 4.1e-59 199.6 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Glutaredoxin PF00462.19 EWM29897.1 - 2.8e-38 129.7 0.0 3.1e-18 65.4 0.0 2.5 2 0 0 2 2 2 2 Glutaredoxin Thioredoxin PF00085.15 EWM29897.1 - 1.5e-09 37.5 0.0 6.3e-09 35.4 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin SH3BGR PF04908.10 EWM29897.1 - 4.7e-05 23.2 0.0 0.32 10.9 0.0 2.4 2 0 0 2 2 2 2 SH3-binding, glutamic acid-rich protein ArsC PF03960.10 EWM29897.1 - 0.00071 19.6 0.0 1.8 8.6 0.0 2.5 2 0 0 2 2 2 2 ArsC family HyaE PF07449.6 EWM29897.1 - 0.029 14.2 0.3 4.9 7.0 0.0 3.7 3 1 0 3 3 3 0 Hydrogenase-1 expression protein HyaE Robl_LC7 PF03259.12 EWM29899.1 - 6.9e-14 51.1 0.0 8.6e-14 50.8 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain Robl_LC7 PF03259.12 EWM29900.1 - 6.9e-14 51.1 0.0 8.6e-14 50.8 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain Robl_LC7 PF03259.12 EWM29901.1 - 6.9e-14 51.1 0.0 8.6e-14 50.8 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain WD40 PF00400.27 EWM29902.1 - 9.7e-18 63.3 4.7 0.0056 16.5 0.1 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ_2 PF13360.1 EWM29902.1 - 3.9e-10 39.5 0.1 0.00011 21.7 0.0 2.9 1 1 1 2 2 2 2 PQQ-like domain PQQ PF01011.16 EWM29902.1 - 7.4e-05 22.0 0.1 0.021 14.3 0.0 3.4 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_3 PF13570.1 EWM29902.1 - 0.00052 20.2 6.6 1.8 8.9 0.4 5.7 6 1 0 6 6 6 2 PQQ-like domain Methyltransf_21 PF05050.7 EWM29904.1 - 1.3e-19 70.7 0.0 1.8e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_18 PF12847.2 EWM29904.1 - 0.00034 21.1 0.0 0.00056 20.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM29904.1 - 0.035 13.8 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Gly-zipper_Omp PF13488.1 EWM29904.1 - 0.11 12.1 0.4 0.11 12.1 0.3 1.7 2 0 0 2 2 2 0 Glycine zipper RelB PF04221.7 EWM29904.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 RelB antitoxin Glycos_transf_1 PF00534.15 EWM29905.1 - 3e-31 108.1 0.0 4.8e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EWM29905.1 - 1.6e-07 31.5 0.0 3.2e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EWM29905.1 - 2.3e-05 24.5 0.0 5.2e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EWM29905.1 - 5.4e-05 23.3 5.0 6e-05 23.2 2.4 1.9 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 EWM29905.1 - 0.0018 18.0 0.9 0.29 10.8 0.0 2.3 1 1 0 2 2 2 2 Glycosyltransferase Family 4 GHMP_kinases_N PF00288.21 EWM29906.1 - 2.4e-13 49.9 0.5 8e-13 48.2 0.2 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EWM29906.1 - 1.9e-06 27.9 0.0 5.1e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Hist_deacetyl PF00850.14 EWM29907.1 - 5.6e-87 291.9 0.0 7.3e-87 291.5 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DUF1115 PF06544.7 EWM29908.1 - 1e-15 57.5 0.0 1.7e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) RWD PF05773.17 EWM29908.1 - 0.0027 17.5 0.0 0.0053 16.6 0.0 1.5 1 1 0 1 1 1 1 RWD domain JmjC PF02373.17 EWM29909.1 - 1.2e-36 125.4 0.5 2.5e-36 124.3 0.3 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 EWM29909.1 - 9.9e-13 47.3 0.1 2.5e-12 46.1 0.1 1.7 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.11 EWM29909.1 - 3e-10 39.9 10.4 5.7e-10 39.1 7.2 1.5 1 0 0 1 1 1 1 C5HC2 zinc finger CDH PF02611.10 EWM29910.1 - 1.5e-09 37.4 0.2 5.6e-08 32.2 0.1 2.2 1 1 0 1 1 1 1 CDP-diacylglycerol pyrophosphatase Nodulin PF02451.10 EWM29910.1 - 0.02 14.3 0.1 0.087 12.2 0.0 1.9 1 1 1 2 2 2 0 Nodulin CDH PF02611.10 EWM29911.1 - 1.8e-09 37.1 0.2 6.4e-08 32.1 0.1 2.2 1 1 0 1 1 1 1 CDP-diacylglycerol pyrophosphatase Nodulin PF02451.10 EWM29911.1 - 0.026 13.9 0.0 0.11 12.0 0.0 2.0 1 1 1 2 2 2 0 Nodulin NCA2 PF08637.5 EWM29912.1 - 7.6e-40 136.6 0.2 2.2e-37 128.5 0.1 2.3 2 0 0 2 2 2 2 ATP synthase regulation protein NCA2 FAST_1 PF06743.10 EWM29914.1 - 1.9e-12 46.7 5.4 0.0053 16.4 0.0 7.7 7 2 3 10 10 10 5 FAST kinase-like protein, subdomain 1 RAP PF08373.5 EWM29914.1 - 3.3e-05 23.5 0.1 0.00012 21.7 0.0 2.0 2 0 0 2 2 2 1 RAP domain TMA7 PF09072.5 EWM29915.1 - 0.047 14.1 1.0 0.047 14.1 0.7 3.5 3 1 0 3 3 3 0 Translation machinery associated TMA7 PorB PF11565.3 EWM29915.1 - 0.058 13.6 0.1 2.6 8.2 0.0 2.5 2 0 0 2 2 2 0 Alpha helical Porin B YihI PF04220.7 EWM29916.1 - 0.026 13.8 0.6 0.03 13.6 0.4 1.1 1 0 0 1 1 1 0 Der GTPase activator (YihI) PK PF00224.16 EWM29917.1 - 1.5e-121 405.3 0.2 2.4e-121 404.6 0.2 1.3 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EWM29917.1 - 2e-21 75.7 0.0 5.5e-21 74.2 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EWM29917.1 - 0.0059 15.5 0.8 0.021 13.7 0.1 2.0 2 1 0 3 3 3 1 HpcH/HpaI aldolase/citrate lyase family p450 PF00067.17 EWM29918.1 - 9.3e-26 90.3 0.0 1.3e-15 56.9 0.0 2.4 3 0 0 3 3 3 2 Cytochrome P450 RRM_1 PF00076.17 EWM29919.1 - 2.9e-19 68.4 0.0 1.5e-13 50.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM29919.1 - 7.8e-19 67.4 0.0 4.4e-12 45.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM29919.1 - 0.002 17.9 0.0 0.0053 16.5 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PBP PF01161.15 EWM29920.1 - 2.3e-24 85.8 0.1 2.9e-24 85.5 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Kinesin PF00225.18 EWM29922.1 - 4.8e-94 314.8 1.0 6.8e-94 314.2 0.7 1.2 1 0 0 1 1 1 1 Kinesin motor domain PH PF00169.24 EWM29922.1 - 1.8e-05 24.8 0.0 0.00012 22.2 0.0 2.3 2 0 0 2 2 2 1 PH domain Bac_DnaA PF00308.13 EWM29922.1 - 0.21 11.2 0.0 2 8.0 0.0 2.1 2 0 0 2 2 2 0 Bacterial dnaA protein tRNA-synt_1b PF00579.20 EWM29924.1 - 8.6e-56 189.1 0.0 1.1e-55 188.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Taeniidae_ag PF05596.6 EWM29924.1 - 0.031 14.1 0.2 0.1 12.4 0.0 2.0 2 0 0 2 2 2 0 Taeniidae antigen tRNA-synt_1b PF00579.20 EWM29925.1 - 8.7e-56 189.1 0.0 1.2e-55 188.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Taeniidae_ag PF05596.6 EWM29925.1 - 0.033 13.9 0.2 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Taeniidae antigen MFMR PF07777.6 EWM29926.1 - 0.024 14.5 0.3 0.029 14.2 0.2 1.1 1 0 0 1 1 1 0 G-box binding protein MFMR TPR_11 PF13414.1 EWM29927.1 - 2.5e-06 27.0 0.0 0.0016 18.0 0.0 2.6 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EWM29927.1 - 6.3e-06 25.7 0.1 0.27 11.2 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EWM29927.1 - 1e-05 24.9 0.1 0.17 11.7 0.0 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EWM29927.1 - 1.7e-05 24.6 0.2 0.0058 16.5 0.0 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.13 EWM29927.1 - 0.0043 16.9 0.0 0.069 13.0 0.0 2.6 1 1 1 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 EWM29927.1 - 0.02 14.7 3.0 1.1 9.3 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_5 PF12688.2 EWM29927.1 - 0.023 14.7 0.8 4 7.5 0.1 2.7 2 0 0 2 2 2 0 Tetratrico peptide repeat TPR_16 PF13432.1 EWM29927.1 - 0.11 13.2 6.3 0.54 10.9 0.0 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EWM29927.1 - 0.11 12.1 0.0 2.2 8.0 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EWM29927.1 - 0.37 11.5 9.8 5.5 7.9 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat CP_ATPgrasp_1 PF04174.8 EWM29928.1 - 0.16 10.5 0.0 0.33 9.5 0.0 1.4 1 0 0 1 1 1 0 A circularly permuted ATPgrasp AMP-binding PF00501.23 EWM29929.1 - 3.4e-60 203.5 0.2 5e-60 203.0 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EWM29929.1 - 2.4e-50 170.7 0.0 4.4e-50 169.9 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EWM29929.1 - 9.1e-11 41.8 0.0 2.1e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EWM29929.1 - 1.6e-09 37.5 0.0 5.7e-09 35.7 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EWM29929.1 - 0.0005 18.8 0.0 0.0044 15.7 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF2117 PF09890.4 EWM29929.1 - 0.15 11.2 0.0 0.33 10.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2117) DNA_primase_S PF01896.14 EWM29932.1 - 3.7e-53 179.2 0.0 7.3e-53 178.2 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit Glutaredoxin PF00462.19 EWM29934.1 - 2.5e-18 65.7 0.2 6.1e-18 64.5 0.1 1.7 1 0 0 1 1 1 1 Glutaredoxin Glyoxalase_2 PF12681.2 EWM29934.1 - 7.6e-16 58.6 0.9 5.6e-11 42.9 0.0 2.5 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase PF00903.20 EWM29934.1 - 5.8e-08 32.7 0.0 0.0081 16.1 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily GST_N_3 PF13417.1 EWM29934.1 - 0.00064 19.8 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.1 EWM29934.1 - 0.0043 17.2 0.0 0.013 15.6 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain DUF836 PF05768.9 EWM29934.1 - 0.016 15.4 0.0 0.038 14.2 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) GST_N_2 PF13409.1 EWM29934.1 - 0.038 13.9 0.0 0.08 12.9 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Glyoxalase_4 PF13669.1 EWM29934.1 - 0.067 13.2 0.2 12 5.9 0.0 2.6 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DSBA PF01323.15 EWM29934.1 - 0.11 12.0 0.1 0.23 11.0 0.0 1.5 2 0 0 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 EWM29934.1 - 0.25 11.3 0.5 0.51 10.3 0.1 1.6 2 0 0 2 2 2 0 Thioredoxin Pox_Ag35 PF03286.9 EWM29935.1 - 1.9 7.9 8.9 2.5 7.5 6.2 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PBP1_TM PF14812.1 EWM29935.1 - 2.9 8.2 14.0 4 7.8 6.9 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_60s PF00428.14 EWM29935.1 - 4.5 7.7 13.3 8.6 6.8 9.2 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Nop14 PF04147.7 EWM29935.1 - 7.7 4.2 14.3 9.5 4.0 9.9 1.1 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.6 EWM29935.1 - 9.4 3.9 9.0 12 3.6 6.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pkinase PF00069.20 EWM29936.1 - 5.3e-62 209.3 0.0 6.5e-62 209.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM29936.1 - 5.5e-26 91.1 0.0 7.9e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EWM29936.1 - 2.1e-07 30.1 0.0 3.6e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EWM29936.1 - 0.12 12.0 1.3 0.98 9.0 0.0 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family PIP49_C PF12260.3 EWM29936.1 - 0.14 11.5 0.1 0.24 10.7 0.1 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Fructosamin_kin PF03881.9 EWM29937.1 - 6.9e-66 222.1 0.0 1e-65 221.5 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EWM29937.1 - 5.6e-14 52.4 0.1 1.1e-13 51.5 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family CBS PF00571.23 EWM29938.1 - 0.0027 17.4 0.8 0.061 13.1 0.0 2.4 2 0 0 2 2 2 2 CBS domain Peptidase_C97 PF05903.9 EWM29939.1 - 8.4e-22 77.5 0.0 1.1e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain SUR7 PF06687.7 EWM29940.1 - 0.02 14.4 14.1 0.3 10.6 0.0 2.9 2 1 0 2 2 2 0 SUR7/PalI family Abhydrolase_6 PF12697.2 EWM29941.1 - 4.1e-31 108.6 2.4 4.6e-31 108.4 1.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM29941.1 - 7e-14 51.7 0.0 2.3e-13 50.1 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EWM29941.1 - 2.3e-10 40.4 0.0 2.9e-09 36.8 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EWM29941.1 - 2.5e-06 27.2 0.0 4.6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase PGAP1 PF07819.8 EWM29941.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Voltage_CLC PF00654.15 EWM29943.1 - 1.3e-22 80.3 5.4 1.3e-22 80.3 3.7 2.1 2 1 1 3 3 3 1 Voltage gated chloride channel GHMP_kinases_N PF00288.21 EWM29944.1 - 5.7e-08 32.7 0.8 1.6e-07 31.3 0.0 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EWM29944.1 - 0.0032 17.6 0.0 0.0079 16.3 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal GidB PF02527.10 EWM29945.1 - 3.8e-33 114.1 0.0 5.3e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.1 EWM29945.1 - 8.1e-09 35.2 0.0 1.4e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EWM29945.1 - 9.2e-05 21.8 0.0 0.00014 21.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EWM29945.1 - 0.0085 15.8 0.0 0.019 14.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM29945.1 - 0.021 15.2 0.0 0.048 14.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 EWM29945.1 - 0.022 13.8 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_18 PF12847.2 EWM29945.1 - 0.073 13.6 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EWM29945.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 EWM29945.1 - 0.2 11.0 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Y_phosphatase2 PF03162.8 EWM29946.1 - 0.0095 15.3 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EWM29946.1 - 0.014 15.6 0.2 0.025 14.8 0.1 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Ribosomal_60s PF00428.14 EWM29947.1 - 2.6e-14 53.3 3.5 3.5e-14 52.9 2.4 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein eIF3_subunit PF08597.5 EWM29947.1 - 0.01 15.4 0.3 0.014 14.9 0.2 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Patatin PF01734.17 EWM29948.1 - 5.6e-09 36.2 1.0 1.3e-08 35.0 0.7 1.7 1 1 0 1 1 1 1 Patatin-like phospholipase ApoLp-III PF07464.6 EWM29949.1 - 3.7e-05 23.7 4.5 5.1e-05 23.3 3.1 1.1 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) FliD_C PF07195.7 EWM29949.1 - 0.0002 20.7 0.5 0.00024 20.4 0.3 1.2 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 C-terminus Remorin_C PF03763.8 EWM29949.1 - 0.058 12.9 8.3 0.11 12.0 5.7 1.4 1 0 0 1 1 1 0 Remorin, C-terminal region RNase_H2-Ydr279 PF09468.5 EWM29949.1 - 0.075 12.2 2.2 0.087 12.0 1.6 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF3956 PF13104.1 EWM29949.1 - 0.11 12.0 0.2 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) Syntaxin PF00804.20 EWM29949.1 - 0.13 12.4 1.5 0.2 11.8 1.1 1.3 1 0 0 1 1 1 0 Syntaxin Casc1 PF12366.3 EWM29949.1 - 0.4 10.1 1.8 0.54 9.7 1.3 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 DUF883 PF05957.8 EWM29949.1 - 0.56 10.6 4.9 0.99 9.8 3.4 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) FliD_C PF07195.7 EWM29950.1 - 0.00058 19.2 0.9 0.00058 19.2 0.6 2.0 1 1 1 2 2 2 1 Flagellar hook-associated protein 2 C-terminus ApoLp-III PF07464.6 EWM29950.1 - 0.0018 18.3 20.8 0.012 15.6 14.2 1.9 1 1 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) DUF3956 PF13104.1 EWM29950.1 - 0.15 11.6 0.2 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) DUF3584 PF12128.3 EWM29950.1 - 0.45 7.7 18.4 0.54 7.5 12.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Mitofilin PF09731.4 EWM29950.1 - 0.59 8.7 20.7 0.85 8.2 14.4 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Phlebovirus_NSM PF07246.6 EWM29950.1 - 0.69 9.0 9.1 0.8 8.8 6.3 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M APG6 PF04111.7 EWM29950.1 - 0.86 8.5 12.1 1.1 8.2 8.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Ndc1_Nup PF09531.5 EWM29950.1 - 1.1 7.5 2.8 1.3 7.3 1.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2317 PF10079.4 EWM29950.1 - 1.6 7.2 8.7 2.1 6.8 6.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) CAF-1_p150 PF11600.3 EWM29950.1 - 1.8 7.8 25.7 2.4 7.5 17.8 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal FUSC PF04632.7 EWM29950.1 - 1.9 6.8 6.0 2.6 6.3 4.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4407 PF14362.1 EWM29950.1 - 2.2 7.1 19.6 3.1 6.6 13.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF883 PF05957.8 EWM29950.1 - 2.2 8.7 27.8 6.3 7.2 4.6 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) SAPS PF04499.10 EWM29950.1 - 4.3 5.8 8.8 5.5 5.5 6.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2413 PF10310.4 EWM29950.1 - 4.6 5.9 18.8 6.4 5.4 13.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Atg14 PF10186.4 EWM29950.1 - 6.6 5.5 9.6 9.4 5.0 6.6 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Hex_IIIa PF02455.11 EWM29950.1 - 7.8 5.0 8.9 9.2 4.8 6.2 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Hid1 PF12722.2 EWM29950.1 - 8.3 3.9 9.4 9.7 3.7 6.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein WXG100 PF06013.7 EWM29950.1 - 8.6 6.4 14.0 5.4 7.1 2.8 2.3 1 1 1 2 2 2 0 Proteins of 100 residues with WXG ApoLp-III PF07464.6 EWM29951.1 - 3.3e-06 27.1 13.7 4.6e-06 26.7 9.5 1.1 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) FliD_C PF07195.7 EWM29951.1 - 0.00049 19.4 0.9 0.00049 19.4 0.6 1.9 1 1 1 2 2 2 1 Flagellar hook-associated protein 2 C-terminus Mitofilin PF09731.4 EWM29951.1 - 0.026 13.1 14.0 0.033 12.8 9.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF3584 PF12128.3 EWM29951.1 - 0.093 10.0 16.7 0.11 9.7 11.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3956 PF13104.1 EWM29951.1 - 0.13 11.8 0.2 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) DUF4407 PF14362.1 EWM29951.1 - 0.27 10.1 14.1 0.38 9.6 9.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2317 PF10079.4 EWM29951.1 - 0.72 8.3 8.2 0.87 8.1 5.7 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) FUSC PF04632.7 EWM29951.1 - 0.9 7.8 6.5 1.2 7.5 4.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family APG6 PF04111.7 EWM29951.1 - 1 8.3 9.6 1.3 8.0 6.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Lyase_8_N PF08124.6 EWM29951.1 - 1.4 7.6 8.0 1.9 7.2 5.5 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain DUF883 PF05957.8 EWM29951.1 - 2.2 8.7 24.6 4.9 7.6 5.0 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Borrelia_P83 PF05262.6 EWM29951.1 - 2.4 6.3 22.3 3.1 5.9 15.5 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein LMBR1 PF04791.11 EWM29951.1 - 2.5 6.5 4.7 2.8 6.4 3.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF966 PF06136.8 EWM29951.1 - 3 7.1 10.4 3.6 6.9 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SAPS PF04499.10 EWM29951.1 - 3.2 6.2 7.2 3.8 6.0 5.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Exonuc_VII_L PF02601.10 EWM29951.1 - 4.1 6.5 14.0 1.3 8.1 7.7 1.5 1 1 1 2 2 2 0 Exonuclease VII, large subunit VSG_B PF13206.1 EWM29951.1 - 4.7 6.2 22.3 6 5.8 15.4 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain DDHD PF02862.12 EWM29951.1 - 4.8 6.9 7.0 6.3 6.5 4.8 1.3 1 0 0 1 1 1 0 DDHD domain Vps53_N PF04100.7 EWM29951.1 - 6 5.5 8.3 15 4.2 5.4 1.8 1 1 1 2 2 2 0 Vps53-like, N-terminal PEP-utilisers_N PF05524.8 EWM29951.1 - 6.1 6.6 15.8 23 4.8 6.6 2.6 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal CENP-Q PF13094.1 EWM29951.1 - 6.4 6.7 13.8 6.4 6.7 8.3 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Spore_coat_CotO PF14153.1 EWM29951.1 - 8 5.8 11.4 12 5.3 7.9 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Rieske PF00355.21 EWM29953.1 - 2.6e-12 46.1 0.0 3.5e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 EWM29953.1 - 1.6e-09 37.3 0.0 2e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain IBR PF01485.16 EWM29954.1 - 5.3e-12 45.4 19.5 8.4e-09 35.1 2.7 3.9 3 1 0 3 3 3 2 IBR domain zf-C3HC4_2 PF13923.1 EWM29954.1 - 0.0078 16.2 7.0 0.0078 16.2 4.8 4.7 4 2 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EWM29954.1 - 0.016 14.9 8.0 0.016 14.9 5.5 4.1 3 1 1 4 4 4 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 EWM29954.1 - 4.5 7.0 8.6 0.11 12.2 0.9 2.1 2 0 0 2 2 2 0 RING-type zinc-finger FH2 PF02181.18 EWM29955.1 - 8.8e-15 54.4 0.0 1.2e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain Smr PF01713.16 EWM29956.1 - 1.2e-08 34.9 0.1 1.8e-08 34.4 0.1 1.3 1 0 0 1 1 1 1 Smr domain FH2 PF02181.18 EWM29957.1 - 0.0014 17.6 0.1 0.0018 17.2 0.1 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain Exo_endo_phos PF03372.18 EWM29958.1 - 8.7e-06 25.8 0.0 0.0011 19.0 0.0 2.3 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Epimerase_Csub PF13950.1 EWM29959.1 - 7.6e-28 96.2 0.4 7.6e-28 96.2 0.3 1.4 2 0 0 2 2 2 1 UDP-glucose 4-epimerase C-term subunit zf-CCCH PF00642.19 EWM29960.1 - 0.0073 15.9 1.1 0.0073 15.9 0.8 2.3 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.4 EWM29960.1 - 0.2 11.1 1.2 0.45 10.0 0.1 2.0 2 0 0 2 2 2 0 Putative zinc-finger domain Epimerase PF01370.16 EWM29962.1 - 4e-21 75.5 0.1 5.5e-21 75.0 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EWM29962.1 - 4.7e-10 39.6 0.2 7.1e-10 39.0 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EWM29962.1 - 5.5e-09 35.1 0.1 7.2e-09 34.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EWM29962.1 - 5.9e-07 29.6 0.1 9.6e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EWM29962.1 - 1.1e-06 27.7 0.0 1.4e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EWM29962.1 - 1.8e-06 27.7 0.2 3.2e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 EWM29962.1 - 0.0003 19.7 0.0 0.00041 19.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 EWM29962.1 - 0.00056 19.2 0.1 0.00074 18.8 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 EWM29962.1 - 0.0032 16.4 0.2 0.0038 16.2 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase UDPG_MGDP_dh_N PF03721.9 EWM29962.1 - 0.0036 16.7 0.2 0.0048 16.2 0.1 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EWM29962.1 - 0.0039 16.8 0.0 0.0049 16.5 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EWM29962.1 - 0.019 14.9 0.1 0.044 13.7 0.0 1.6 2 0 0 2 2 2 0 TrkA-N domain ELFV_dehydrog PF00208.16 EWM29962.1 - 0.02 14.4 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DAO PF01266.19 EWM29962.1 - 0.024 13.5 2.0 0.027 13.4 0.6 1.5 1 1 1 2 2 2 0 FAD dependent oxidoreductase Pkinase PF00069.20 EWM29965.1 - 3.6e-50 170.5 0.0 4.4e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM29965.1 - 1.4e-28 99.6 0.0 1.7e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EWM29965.1 - 0.0031 16.5 0.0 0.0043 16.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EWM29965.1 - 0.0066 16.2 0.1 0.017 14.9 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EWM29965.1 - 0.055 12.2 0.0 0.08 11.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Amino_oxidase PF01593.19 EWM29966.1 - 9.9e-62 209.4 0.0 1.2e-61 209.1 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EWM29966.1 - 2.3e-13 49.9 0.8 2.3e-13 49.9 0.5 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EWM29966.1 - 2.4e-07 29.9 1.4 4e-05 22.6 0.9 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EWM29966.1 - 6.7e-05 23.2 0.4 0.34 11.3 1.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EWM29966.1 - 0.00062 18.7 1.9 0.05 12.4 1.0 2.2 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.9 EWM29966.1 - 0.0014 17.1 0.6 0.009 14.5 0.6 2.2 3 0 0 3 3 3 1 HI0933-like protein Rossmann-like PF10727.4 EWM29966.1 - 0.0058 16.3 0.0 0.017 14.8 0.0 1.8 2 0 0 2 2 2 1 Rossmann-like domain FAD_binding_3 PF01494.14 EWM29966.1 - 0.01 14.9 0.3 0.016 14.2 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 EWM29966.1 - 0.012 15.4 0.2 0.04 13.8 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Strep_67kDa_ant PF06100.6 EWM29966.1 - 0.046 12.0 0.2 4.2 5.6 0.0 2.1 2 0 0 2 2 2 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family FAD_oxidored PF12831.2 EWM29966.1 - 0.15 11.0 0.3 0.31 10.0 0.2 1.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF819 PF05684.7 EWM29967.1 - 3.1e-74 250.0 18.2 4.1e-74 249.6 12.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF819) TRAM_LAG1_CLN8 PF03798.11 EWM29968.1 - 3.9e-31 108.1 27.0 5.7e-31 107.6 18.7 1.2 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 EWM29968.1 - 0.00029 20.2 0.7 0.33 10.4 0.2 2.8 2 0 0 2 2 2 2 TRAM1-like protein RNase_T PF00929.19 EWM29970.1 - 4.5e-23 82.3 0.0 7e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EWM29970.1 - 0.064 12.7 0.0 0.14 11.5 0.0 1.5 2 0 0 2 2 2 0 3'-5' exonuclease YCII PF03795.9 EWM29970.1 - 0.099 12.8 0.1 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 YCII-related domain UCH_1 PF13423.1 EWM29971.1 - 2.2e-06 27.3 0.0 3.2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PQQ_3 PF13570.1 EWM29971.1 - 0.00028 21.0 0.1 2.5 8.5 0.0 4.2 4 0 0 4 4 4 2 PQQ-like domain UCH PF00443.24 EWM29971.1 - 0.083 11.9 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase PK PF00224.16 EWM29972.1 - 2.3e-129 430.9 0.5 3.1e-129 430.5 0.4 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EWM29972.1 - 4e-21 74.7 0.0 1e-20 73.3 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EWM29972.1 - 0.00032 19.6 1.0 0.0013 17.6 0.2 2.0 1 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family E3_UbLigase_R4 PF13764.1 EWM29973.1 - 0.02 12.8 1.1 0.37 8.6 0.0 2.1 1 1 1 2 2 2 0 E3 ubiquitin-protein ligase UBR4 LEA_2 PF03168.8 EWM29974.1 - 0.0071 16.6 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 Late embryogenesis abundant protein RhoGAP PF00620.22 EWM29975.1 - 6.9e-08 32.2 0.0 1.9e-05 24.3 0.0 2.8 2 1 0 2 2 2 2 RhoGAP domain Drc1-Sld2 PF11719.3 EWM29975.1 - 0.0013 17.8 0.5 0.0013 17.8 0.3 2.3 2 0 0 2 2 2 1 DNA replication and checkpoint protein SH3_9 PF14604.1 EWM29975.1 - 0.13 11.8 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain His_Phos_1 PF00300.17 EWM29976.1 - 8.6e-08 32.4 0.0 1.2e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Glyco_hydro_9 PF00759.14 EWM29977.1 - 4.1e-111 372.0 1.8 5.1e-111 371.6 1.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Utp14 PF04615.8 EWM29978.1 - 4.2e-39 134.3 13.4 3e-28 98.4 0.0 2.6 2 1 0 2 2 2 2 Utp14 protein COPIIcoated_ERV PF07970.7 EWM29979.1 - 2.4e-56 190.8 0.0 3.4e-56 190.3 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EWM29979.1 - 4.5e-25 87.4 1.1 7.6e-25 86.7 0.7 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) SR-25 PF10500.4 EWM29981.1 - 4.6 6.6 7.2 8.2 5.8 5.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein UQ_con PF00179.21 EWM29983.1 - 5.9e-52 174.8 0.0 6.9e-52 174.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EWM29983.1 - 0.00098 18.8 0.1 0.0021 17.8 0.0 1.5 1 1 1 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 EWM29983.1 - 0.019 14.8 0.0 0.032 14.1 0.0 1.6 1 1 0 1 1 1 0 RWD domain Sigma70_ner PF04546.8 EWM29983.1 - 0.073 12.6 2.6 0.096 12.2 1.8 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.1 EWM29983.1 - 0.2 11.9 6.4 0.34 11.2 4.4 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BTV_NS2 PF04514.7 EWM29983.1 - 2.1 7.1 7.4 2.8 6.7 5.1 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Nucleoplasmin PF03066.10 EWM29983.1 - 3 7.3 9.5 4.1 6.9 6.6 1.2 1 0 0 1 1 1 0 Nucleoplasmin CDC45 PF02724.9 EWM29983.1 - 3.6 5.4 6.8 4.8 5.0 4.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EWM29983.1 - 4.6 5.0 6.6 5.6 4.7 4.6 1.1 1 0 0 1 1 1 0 Nop14-like family UQ_con PF00179.21 EWM29984.1 - 2.9e-48 162.8 0.4 2.9e-47 159.6 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EWM29984.1 - 0.0039 16.9 0.0 0.006 16.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EWM29984.1 - 0.061 13.2 0.0 0.079 12.8 0.0 1.2 1 0 0 1 1 1 0 RWD domain DUF2570 PF10828.3 EWM29985.1 - 0.0028 17.2 2.2 0.0051 16.3 1.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2570) OmpH PF03938.9 EWM29985.1 - 0.0097 15.8 7.2 0.012 15.6 5.0 1.3 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) DUF4407 PF14362.1 EWM29985.1 - 0.24 10.3 4.7 0.28 10.1 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_12 PF13424.1 EWM29988.1 - 7.8e-50 166.7 21.3 1.5e-16 60.1 0.4 5.4 3 2 3 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.1 EWM29988.1 - 2.7e-32 109.7 18.2 1.6e-06 27.8 0.1 8.1 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.1 EWM29988.1 - 1.7e-20 71.0 14.5 2.2e-05 23.9 0.2 8.1 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.1 EWM29988.1 - 2.3e-20 72.0 14.1 2.7e-06 26.9 2.0 5.9 4 1 2 6 6 6 6 TPR repeat TPR_8 PF13181.1 EWM29988.1 - 8e-19 65.9 11.4 0.013 15.1 0.0 8.0 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.23 EWM29988.1 - 3.8e-18 64.2 17.0 0.00016 21.0 0.1 7.3 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 EWM29988.1 - 8.2e-16 56.5 21.7 0.00054 19.6 0.4 7.8 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 EWM29988.1 - 1.7e-14 54.0 15.3 0.00041 20.9 1.2 6.0 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 EWM29988.1 - 6.1e-12 45.0 20.7 0.0098 16.4 0.8 8.0 5 2 3 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 EWM29988.1 - 1.2e-06 28.7 19.1 0.33 11.3 0.5 6.4 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 EWM29988.1 - 2.2e-05 24.2 7.0 0.55 10.5 0.0 5.9 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 EWM29988.1 - 0.00012 22.2 19.6 3.4 8.3 0.1 7.8 9 0 0 9 9 8 1 Tetratricopeptide repeat Apc5 PF12862.2 EWM29988.1 - 0.081 12.7 1.4 6.7 6.6 0.0 3.5 4 1 1 5 5 5 0 Anaphase-promoting complex subunit 5 DUF2225 PF09986.4 EWM29988.1 - 0.14 11.5 1.2 11 5.3 0.1 3.1 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) PLDc_N PF13396.1 EWM29989.1 - 6.2e-06 25.7 14.7 1.8e-05 24.2 10.2 1.7 1 1 0 1 1 1 1 Phospholipase_D-nuclease N-terminal MARVEL PF01284.18 EWM29989.1 - 0.039 13.7 3.8 0.044 13.6 2.6 1.0 1 0 0 1 1 1 0 Membrane-associating domain DUF2788 PF10981.3 EWM29989.1 - 0.078 12.7 6.3 0.15 11.8 3.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2788) Glucos_trans_II PF14264.1 EWM29989.1 - 0.092 11.7 4.1 0.097 11.6 2.9 1.0 1 0 0 1 1 1 0 Glucosyl transferase GtrII DUF4131 PF13567.1 EWM29989.1 - 0.88 8.9 3.4 0.93 8.8 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF1049 PF06305.6 EWM29989.1 - 4.2 6.9 7.1 0.34 10.4 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF805 PF05656.9 EWM29989.1 - 8.7 6.1 7.1 20 4.9 4.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF805) Lipase_GDSL PF00657.17 EWM29990.1 - 1.5e-08 34.8 0.1 8e-07 29.1 0.0 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EWM29990.1 - 1.4e-07 31.8 0.0 1.8e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Hydrolase_6 PF13344.1 EWM29991.1 - 5.3e-15 55.1 0.0 8.5e-15 54.4 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EWM29991.1 - 7.7e-11 41.5 0.0 1.4e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EWM29991.1 - 2.6e-05 24.5 0.0 0.2 11.8 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EWM29991.1 - 0.11 12.8 0.0 19 5.5 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Diphthamide_syn PF01866.12 EWM29993.1 - 2.3e-107 358.7 0.0 2.7e-107 358.5 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Nif11 PF07862.6 EWM29993.1 - 0.15 12.0 0.0 0.8 9.6 0.0 2.2 2 0 0 2 2 2 0 Nitrogen fixation protein of unknown function CRM1_C PF08767.6 EWM29994.1 - 0.00019 20.4 0.0 0.00044 19.2 0.0 1.5 2 0 0 2 2 2 1 CRM1 C terminal DUF1876 PF08962.6 EWM29994.1 - 0.094 12.5 0.1 0.66 9.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1876) Rhomboid PF01694.17 EWM29995.1 - 8.3e-18 64.8 3.8 1.7e-17 63.8 2.6 1.4 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.5 EWM29995.1 - 0.16 12.3 0.3 0.16 12.3 0.2 1.9 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) Kinesin PF00225.18 EWM29996.1 - 1.8e-83 280.0 0.0 1.2e-82 277.3 0.0 2.0 1 1 0 1 1 1 1 Kinesin motor domain DUF3306 PF11748.3 EWM29996.1 - 1 10.0 6.0 3.7 8.2 4.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) MIP PF00230.15 EWM29997.1 - 1.2e-20 73.9 10.7 1.7e-20 73.4 7.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein Ribosomal_L19e PF01280.15 EWM29998.1 - 4.4e-59 198.4 13.3 4.4e-59 198.4 9.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L19e RNase_H2-Ydr279 PF09468.5 EWM29998.1 - 0.041 13.0 2.9 0.047 12.8 2.0 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF972 PF06156.8 EWM29998.1 - 2.9 8.2 6.8 22 5.4 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF972) SH2_2 PF14633.1 EWM30000.1 - 3.1e-31 108.1 0.2 4.9e-31 107.5 0.1 1.2 1 0 0 1 1 1 1 SH2 domain DLD PF14878.1 EWM30000.1 - 6.2e-15 55.3 0.0 9.4e-14 51.5 0.0 2.5 1 1 0 1 1 1 1 Death-like domain of SPT6 SH2 PF00017.19 EWM30000.1 - 4.7e-06 26.3 0.0 1.2e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 SH2 domain S1 PF00575.18 EWM30000.1 - 0.00016 21.6 0.0 0.00046 20.2 0.0 1.9 1 1 0 1 1 1 1 S1 RNA binding domain VirE1 PF12189.3 EWM30000.1 - 0.064 13.3 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 Single-strand DNA-binding protein Prominin PF05478.6 EWM30000.1 - 0.15 9.5 0.3 0.72 7.3 0.1 1.8 2 0 0 2 2 2 0 Prominin DUF3812 PF12757.2 EWM30000.1 - 6 6.8 9.8 0.16 11.9 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3812) DUF3493 PF11998.3 EWM30002.1 - 1.2e-13 50.7 0.0 2.5e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3493) CAP_N PF01213.14 EWM30002.1 - 0.65 9.2 4.7 1 8.5 3.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 EWM30002.1 - 1.1 8.5 4.5 1.8 7.8 3.1 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator AAA PF00004.24 EWM30003.1 - 6.6e-92 304.6 0.0 4.6e-47 159.5 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EWM30003.1 - 1e-15 57.4 0.0 3.2e-08 32.9 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EWM30003.1 - 4.9e-12 46.2 0.6 1.6e-05 25.0 0.1 3.0 2 2 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.1 EWM30003.1 - 1.2e-10 41.3 0.0 8.7e-05 22.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EWM30003.1 - 1.5e-10 41.9 0.0 0.00026 21.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EWM30003.1 - 1.8e-10 41.0 0.0 0.0083 16.2 0.0 4.1 2 2 1 3 3 3 2 AAA domain AAA_2 PF07724.9 EWM30003.1 - 2.3e-10 40.6 0.0 0.00018 21.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EWM30003.1 - 1.1e-09 38.1 0.2 0.00065 19.4 0.0 3.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EWM30003.1 - 6.1e-09 35.8 0.0 0.0041 17.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EWM30003.1 - 6.7e-09 35.3 0.1 0.0016 17.9 0.1 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein TIP49 PF06068.8 EWM30003.1 - 1.1e-08 34.2 0.0 0.00068 18.4 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 EWM30003.1 - 1.9e-08 33.9 3.9 0.042 13.2 0.0 4.1 2 2 2 4 4 4 2 AAA domain Zeta_toxin PF06414.7 EWM30003.1 - 2.7e-08 33.1 0.1 0.0047 16.0 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.1 EWM30003.1 - 1e-07 32.3 0.0 0.0078 16.5 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EWM30003.1 - 1.2e-07 31.3 6.3 0.0092 15.7 0.1 4.2 4 0 0 4 4 4 2 Part of AAA domain RNA_helicase PF00910.17 EWM30003.1 - 1.8e-07 31.3 0.0 0.025 14.7 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 EWM30003.1 - 4.3e-07 30.0 0.0 0.028 14.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EWM30003.1 - 4.4e-07 29.2 0.6 0.026 13.7 0.1 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EWM30003.1 - 4.7e-06 26.3 0.5 0.24 11.0 0.0 3.3 2 1 1 3 3 3 2 NACHT domain ABC_tran PF00005.22 EWM30003.1 - 5.8e-06 26.6 0.0 0.08 13.2 0.0 2.6 2 1 0 2 2 2 2 ABC transporter KaiC PF06745.8 EWM30003.1 - 3e-05 23.2 0.2 0.8 8.7 0.0 3.2 2 1 0 3 3 3 2 KaiC AAA_3 PF07726.6 EWM30003.1 - 3.8e-05 23.2 0.0 0.092 12.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 EWM30003.1 - 0.00012 22.1 0.0 0.12 12.4 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain Rad17 PF03215.10 EWM30003.1 - 0.00024 19.9 0.0 0.49 9.0 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein Sigma54_activat PF00158.21 EWM30003.1 - 0.00031 20.2 0.1 0.28 10.6 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain Arch_ATPase PF01637.13 EWM30003.1 - 0.00032 20.4 0.0 1.7 8.3 0.0 3.3 2 2 1 3 3 3 2 Archaeal ATPase PhoH PF02562.11 EWM30003.1 - 0.00046 19.4 0.3 0.79 8.9 0.1 2.5 2 0 0 2 2 2 2 PhoH-like protein NB-ARC PF00931.17 EWM30003.1 - 0.00049 19.0 0.1 0.58 8.9 0.0 2.2 2 0 0 2 2 2 2 NB-ARC domain Cytidylate_kin2 PF13189.1 EWM30003.1 - 0.00052 19.9 0.0 0.25 11.2 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family UPF0079 PF02367.12 EWM30003.1 - 0.00059 19.4 0.2 0.77 9.4 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 Viral_helicase1 PF01443.13 EWM30003.1 - 0.0009 18.8 0.0 0.99 8.8 0.0 2.2 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Parvo_NS1 PF01057.12 EWM30003.1 - 0.0017 17.2 0.1 0.25 10.1 0.0 2.1 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 SKI PF01202.17 EWM30003.1 - 0.0019 18.1 0.0 1.5 8.6 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase ATP-synt_ab PF00006.20 EWM30003.1 - 0.003 17.0 0.0 0.26 10.7 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.1 EWM30003.1 - 0.0054 16.3 0.2 0.76 9.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EWM30003.1 - 0.015 14.8 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EWM30003.1 - 0.018 14.0 0.0 1.7 7.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PduV-EutP PF10662.4 EWM30003.1 - 0.02 14.3 0.0 3.3 7.2 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 EWM30003.1 - 0.025 14.2 0.1 11 5.6 0.0 2.8 2 1 1 3 3 2 0 NTPase AAA_10 PF12846.2 EWM30003.1 - 0.03 13.7 0.5 2 7.7 0.0 2.9 3 0 0 3 3 2 0 AAA-like domain DUF815 PF05673.8 EWM30003.1 - 0.032 13.1 0.0 2.8 6.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) CPT PF07931.7 EWM30003.1 - 0.032 13.8 0.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Bac_DnaA PF00308.13 EWM30003.1 - 0.14 11.7 0.1 9.8 5.7 0.0 2.6 2 1 0 2 2 2 0 Bacterial dnaA protein Zot PF05707.7 EWM30003.1 - 0.16 11.4 0.0 6.3 6.2 0.0 3.0 4 0 0 4 4 3 0 Zonular occludens toxin (Zot) T2SE PF00437.15 EWM30003.1 - 0.17 10.7 0.0 7 5.4 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein FeoB_N PF02421.13 EWM30003.1 - 0.24 10.6 0.2 8.9 5.5 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B DAP3 PF10236.4 EWM30003.1 - 0.24 10.2 0.1 12 4.7 0.0 2.7 2 1 1 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 SRPRB PF09439.5 EWM30003.1 - 0.26 10.4 0.0 16 4.6 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_23 PF13476.1 EWM30003.1 - 0.27 11.5 0.1 16 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 EWM30003.1 - 0.33 10.7 0.0 19 4.9 0.0 2.6 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit DNA_binding_1 PF01035.15 EWM30004.1 - 3.6e-22 77.9 0.1 7.8e-22 76.8 0.0 1.5 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain HHH_7 PF14635.1 EWM30006.1 - 3.8e-15 55.8 0.0 1.2e-14 54.3 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif YqgF PF14639.1 EWM30006.1 - 3.9e-13 49.2 0.0 1.3e-12 47.5 0.0 1.9 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.1 EWM30006.1 - 8.2e-12 45.1 0.2 2.9e-11 43.3 0.2 1.9 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 TPR_11 PF13414.1 EWM30007.1 - 2.5e-23 81.4 11.0 3.4e-10 39.4 0.5 3.3 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 EWM30007.1 - 2.2e-19 68.1 10.6 1.2e-06 27.8 0.0 5.7 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 EWM30007.1 - 1.8e-17 61.7 10.8 1e-05 25.0 0.0 5.7 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EWM30007.1 - 2e-13 50.6 5.5 3.9e-05 24.1 0.0 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 EWM30007.1 - 3.3e-12 45.5 9.5 8.6e-05 22.4 0.1 4.4 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 EWM30007.1 - 1.6e-11 43.0 5.4 0.07 12.9 0.0 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EWM30007.1 - 7.3e-11 41.6 8.0 0.0013 19.1 0.0 5.0 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.1 EWM30007.1 - 1.9e-10 40.9 8.2 1.9e-05 24.8 0.3 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EWM30007.1 - 2.4e-10 40.2 12.4 0.00021 21.1 1.0 3.9 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.1 EWM30007.1 - 1.4e-08 33.8 7.7 0.0046 16.6 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.1 EWM30007.1 - 7.6e-06 25.1 3.2 0.1 11.6 0.1 3.4 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EWM30007.1 - 3.5e-05 23.9 11.7 0.075 13.5 0.0 5.6 5 1 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 EWM30007.1 - 0.00013 22.0 6.1 0.052 13.6 1.8 2.3 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EWM30007.1 - 0.001 18.8 1.2 1.1 9.2 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.1 EWM30007.1 - 0.007 16.4 0.3 0.87 9.7 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Glyco_hyd_65N_2 PF14498.1 EWM30007.1 - 0.065 12.9 0.1 2.4 7.8 0.0 2.2 1 1 1 2 2 2 0 Glycosyl hydrolase family 65, N-terminal domain ChAPs PF09295.5 EWM30007.1 - 0.31 9.7 0.2 2.1 7.0 0.0 1.9 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.1 EWM30007.1 - 1.1 9.2 11.8 4.8 7.2 0.3 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat ATP_bind_3 PF01171.15 EWM30009.1 - 1.1e-05 24.9 0.0 1.2e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 PP-loop family DUF2823 PF11034.3 EWM30012.1 - 0.14 12.3 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2823) Maf_N PF08383.6 EWM30013.1 - 0.099 12.2 0.4 0.32 10.5 0.1 2.0 2 0 0 2 2 2 0 Maf N-terminal region PhageP22-tail PF09251.5 EWM30014.1 - 0.064 11.5 0.0 0.084 11.1 0.0 1.1 1 0 0 1 1 1 0 Salmonella phage P22 tail-spike SR-25 PF10500.4 EWM30014.1 - 2.2 7.6 11.2 3.5 7.0 7.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 EWM30014.1 - 4.7 7.3 10.2 7.7 6.5 7.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DnaJ PF00226.26 EWM30015.1 - 1.1e-14 53.8 0.0 1.6e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.8 EWM30015.1 - 1.1e-12 47.2 0.0 1.6e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 CSL zinc finger Methyltransf_26 PF13659.1 EWM30016.1 - 2.7e-14 53.2 0.0 5.7e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EWM30016.1 - 3.7e-08 32.9 0.0 0.00028 20.3 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_18 PF12847.2 EWM30016.1 - 4.9e-08 33.5 0.0 1.7e-07 31.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM30016.1 - 8.6e-07 28.6 0.0 2.1e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM30016.1 - 0.0018 18.6 0.0 0.0039 17.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM30016.1 - 0.0045 16.7 0.0 0.0076 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM30016.1 - 0.0053 17.1 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EWM30016.1 - 0.013 14.9 0.0 2.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical protein 95 UPF0020 PF01170.13 EWM30016.1 - 0.013 15.0 0.0 5.3 6.5 0.0 2.2 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.7 EWM30016.1 - 0.029 14.8 0.0 0.082 13.3 0.0 1.8 2 0 0 2 2 1 0 Methyltransferase domain PrmA PF06325.8 EWM30016.1 - 0.089 11.8 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Eco57I PF07669.6 EWM30016.1 - 0.2 12.0 0.0 0.32 11.3 0.0 1.3 1 0 0 1 1 1 0 Eco57I restriction-modification methylase WD40 PF00400.27 EWM30017.1 - 7.1e-23 79.6 5.1 9e-06 25.3 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EWM30017.1 - 0.0012 17.1 0.0 0.055 11.5 0.0 2.7 3 0 0 3 3 3 1 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EWM30017.1 - 0.024 14.0 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 PQQ-like domain Peptidase_S41 PF03572.13 EWM30018.1 - 1.6e-48 164.3 0.0 2.3e-48 163.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S41 PDZ PF00595.19 EWM30018.1 - 3.7e-08 33.4 0.0 3.1e-07 30.4 0.0 2.2 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EWM30018.1 - 0.0038 17.0 0.2 0.0089 15.8 0.1 1.6 1 0 0 1 1 1 1 PDZ domain Tricorn_C1 PF14684.1 EWM30018.1 - 0.0081 16.0 0.2 0.014 15.2 0.1 1.4 1 0 0 1 1 1 1 Tricorn protease C1 domain Polyketide_cyc2 PF10604.4 EWM30018.1 - 0.039 14.1 0.0 0.087 12.9 0.0 1.7 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport DUF4646 PF15496.1 EWM30018.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) CHGN PF05679.11 EWM30019.1 - 0.058 12.1 0.0 0.063 11.9 0.0 1.0 1 0 0 1 1 1 0 Chondroitin N-acetylgalactosaminyltransferase Fapy_DNA_glyco PF01149.19 EWM30020.1 - 6.1e-22 78.1 1.0 2.2e-21 76.3 0.0 2.2 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 EWM30020.1 - 1.2e-16 60.2 0.0 2.1e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain DUF2525 PF10733.4 EWM30020.1 - 0.0061 16.3 0.1 0.042 13.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2525) Ribosomal_S13 PF00416.17 EWM30020.1 - 0.02 15.3 0.0 0.048 14.1 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S13/S18 FbpA PF05833.6 EWM30020.1 - 0.05 12.1 0.0 0.074 11.5 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) PGA2 PF07543.7 EWM30020.1 - 0.57 9.9 5.1 0.99 9.2 3.6 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 SNARE_assoc PF09335.6 EWM30022.1 - 1.1e-10 41.7 1.8 1.3e-10 41.5 0.5 1.6 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF2910 PF11139.3 EWM30022.1 - 0.011 14.8 0.9 0.016 14.3 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2910) Cation_ATPase_N PF00690.21 EWM30025.1 - 5.1e-09 35.4 0.0 1.2e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus E1-E2_ATPase PF00122.15 EWM30025.1 - 4.7e-08 32.3 0.1 8.1e-08 31.5 0.1 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Ni_hydr_CYTB PF01292.15 EWM30025.1 - 0.28 10.5 2.6 0.55 9.5 0.3 2.0 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 UPF0547 PF10571.4 EWM30026.1 - 0.057 13.1 1.5 0.095 12.4 1.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 UPF0547 PF10571.4 EWM30027.1 - 0.058 13.1 1.5 0.096 12.4 1.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 Cation_ATPase_C PF00689.16 EWM30032.1 - 4.5e-12 45.8 0.0 6.2e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Lipase_3 PF01764.20 EWM30033.1 - 9.1e-34 116.0 0.0 1.4e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EWM30033.1 - 0.00041 20.3 0.5 0.00081 19.3 0.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 EWM30033.1 - 0.011 15.4 0.0 0.04 13.6 0.0 1.9 2 0 0 2 2 2 0 Cutinase DUF2974 PF11187.3 EWM30033.1 - 0.021 14.1 0.1 1.2 8.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 EWM30033.1 - 0.032 14.0 0.0 0.058 13.1 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.15 EWM30033.1 - 0.05 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.15 EWM30033.1 - 0.089 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Peptidase_S10 PF00450.17 EWM30035.1 - 2.3e-110 369.6 0.3 3e-110 369.2 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase BmKX PF09132.5 EWM30035.1 - 0.019 14.8 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 BmKX NPL4 PF05021.10 EWM30037.1 - 1.5e-10 40.7 0.0 4.1e-10 39.3 0.0 1.5 1 1 0 1 1 1 1 NPL4 family Peptidase_S10 PF00450.17 EWM30038.1 - 2.1e-123 412.5 0.2 2.6e-123 412.2 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EWM30038.1 - 0.0015 18.4 0.0 0.084 12.7 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family HNH PF01844.18 EWM30039.1 - 1.1e-06 28.3 0.0 1.1e-06 28.3 0.0 2.0 2 0 0 2 2 2 1 HNH endonuclease SAP PF02037.22 EWM30039.1 - 0.0045 16.4 0.0 0.015 14.7 0.0 1.9 1 0 0 1 1 1 1 SAP domain Cytochrom_C1 PF02167.10 EWM30039.1 - 0.21 11.1 0.1 0.4 10.2 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C1 family DUF4460 PF14687.1 EWM30040.1 - 1.1e-13 50.9 0.8 2.6e-13 49.6 0.6 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4460) YopE_N PF09020.5 EWM30040.1 - 3 7.8 8.6 0.19 11.7 1.4 2.3 2 1 1 3 3 3 0 YopE, N terminal Ank_2 PF12796.2 EWM30041.1 - 2.4e-25 88.6 0.0 2.6e-13 50.1 0.0 2.9 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EWM30041.1 - 4.7e-18 65.1 1.5 7.6e-08 32.6 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EWM30041.1 - 1.9e-16 58.9 2.6 2.5e-05 23.8 0.2 4.6 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 EWM30041.1 - 5.9e-16 58.1 3.0 0.00025 21.1 0.0 4.9 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM30041.1 - 1.3e-14 52.8 2.7 1.2e-06 28.1 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeat Peptidase_M16_C PF05193.16 EWM30042.1 - 1.6e-31 109.4 0.0 5.1e-20 71.9 0.0 3.7 4 1 0 4 4 4 3 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EWM30042.1 - 1.4e-09 37.8 0.1 4.3e-09 36.2 0.1 1.9 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EWM30043.1 - 8.5e-23 80.9 0.0 2.9e-20 72.7 0.0 3.2 3 1 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EWM30043.1 - 1.1e-09 38.1 0.1 2.8e-09 36.8 0.1 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Maf PF02545.9 EWM30044.1 - 7.3e-45 152.5 0.0 9.8e-45 152.0 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein GMC_oxred_N PF00732.14 EWM30046.1 - 8.1e-47 159.7 0.0 4e-45 154.2 0.0 2.6 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EWM30046.1 - 4e-24 85.5 0.0 8.1e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EWM30046.1 - 3.7e-07 29.3 0.7 1.2e-06 27.7 0.5 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EWM30046.1 - 0.00032 20.6 0.0 0.00083 19.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EWM30046.1 - 0.0022 16.9 0.1 0.0033 16.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EWM30046.1 - 0.0078 15.1 0.6 0.034 12.9 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain ApbA PF02558.11 EWM30046.1 - 0.17 11.2 0.0 0.35 10.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DapB_N PF01113.15 EWM30047.1 - 2.5e-11 43.5 0.3 8.7e-11 41.8 0.2 1.9 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DapB_C PF05173.9 EWM30047.1 - 7.7e-07 28.9 0.0 2.4e-06 27.3 0.0 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus DapB_N PF01113.15 EWM30048.1 - 1.8e-11 44.0 0.3 5e-11 42.5 0.2 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus HSP90 PF00183.13 EWM30050.1 - 1.6e-84 284.2 1.1 2.6e-80 270.3 0.0 2.1 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.1 EWM30050.1 - 4.5e-11 42.5 0.1 1e-10 41.3 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EWM30050.1 - 1.4e-05 24.7 0.1 5e-05 22.9 0.1 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TRH PF05438.7 EWM30050.1 - 0.025 13.9 0.2 0.062 12.6 0.1 1.6 1 0 0 1 1 1 0 Thyrotropin-releasing hormone (TRH) PRESAN PF09687.5 EWM30050.1 - 0.57 10.2 5.5 5.3 7.1 0.3 2.4 2 0 0 2 2 2 0 Plasmodium RESA N-terminal RNase_PH PF01138.16 EWM30053.1 - 1.1e-29 103.3 0.1 2.8e-29 102.0 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EWM30053.1 - 1.5e-05 24.8 0.1 2.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Nuc_sug_transp PF04142.10 EWM30054.1 - 7.3e-05 21.9 2.4 0.00013 21.1 1.7 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 EWM30054.1 - 0.0055 16.7 1.0 0.0055 16.7 0.7 3.2 2 1 0 2 2 2 1 EamA-like transporter family DUF914 PF06027.7 EWM30054.1 - 0.011 14.5 3.9 0.018 13.8 2.7 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) UbiA PF01040.13 EWM30055.1 - 3.8e-29 101.7 14.7 3.8e-29 101.7 10.2 1.8 2 0 0 2 2 2 1 UbiA prenyltransferase family UBN2_2 PF14227.1 EWM30056.1 - 1.2e-06 28.0 1.0 1.8e-06 27.5 0.7 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EWM30056.1 - 3.6e-06 26.7 0.1 6.3e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF1759 PF03564.10 EWM30056.1 - 2e-05 24.4 0.3 0.00011 22.0 0.1 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1759) zf-CCHC_5 PF14787.1 EWM30056.1 - 0.74 9.3 3.1 1.5 8.3 2.1 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger KH_1 PF00013.24 EWM30057.1 - 3.8e-09 36.0 0.3 8.5e-09 34.9 0.2 1.6 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EWM30057.1 - 1.5e-06 27.7 0.5 3.3e-06 26.6 0.4 1.6 1 0 0 1 1 1 1 KH domain SF3b1 PF08920.5 EWM30057.1 - 0.0073 16.3 1.6 0.0073 16.3 1.1 1.9 2 0 0 2 2 2 1 Splicing factor 3B subunit 1 DUF837 PF05769.6 EWM30057.1 - 0.0083 15.6 0.6 0.017 14.6 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF837) zf-CCHC PF00098.18 EWM30057.1 - 0.018 14.9 2.1 0.018 14.9 1.4 2.2 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.1 EWM30057.1 - 1.4 8.6 7.7 0.36 10.5 1.8 2.3 1 1 1 2 2 2 0 Zinc knuckle HNF-1_N PF04814.8 EWM30057.1 - 4.1 7.4 10.6 0.24 11.4 1.3 2.7 3 0 0 3 3 3 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Mito_carr PF00153.22 EWM30058.1 - 1.9e-40 136.4 4.4 4.5e-14 51.9 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Cation_ATPase_C PF00689.16 EWM30060.1 - 0.0058 16.1 2.0 0.0095 15.4 1.4 1.3 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus DUF3735 PF12537.3 EWM30060.1 - 0.03 14.3 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3735) DUF202 PF02656.10 EWM30060.1 - 3.7 7.8 6.2 16 5.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF202) PMP22_Claudin PF00822.15 EWM30061.1 - 0.0031 17.1 7.9 0.0088 15.7 4.2 1.9 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin family SURF4 PF02077.10 EWM30061.1 - 0.037 13.3 1.0 0.037 13.3 0.7 1.9 1 1 1 2 2 2 0 SURF4 family DUF2231 PF09990.4 EWM30061.1 - 0.06 13.6 8.2 0.18 12.1 0.3 2.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2231) Bax1-I PF01027.15 EWM30061.1 - 0.28 10.7 14.7 0.46 10.0 10.2 1.3 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Tmpp129 PF10272.4 EWM30061.1 - 0.3 9.7 1.7 0.21 10.2 0.1 1.5 2 0 0 2 2 2 0 Putative transmembrane protein precursor DPM3 PF08285.6 EWM30061.1 - 1.7 8.5 5.7 1.2 9.0 0.2 2.4 1 1 2 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF2512 PF10710.4 EWM30061.1 - 2.8 7.4 8.6 0.69 9.3 0.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2512) DUF2975 PF11188.3 EWM30061.1 - 7 6.3 11.1 1.4 8.6 2.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2975) MARVEL PF01284.18 EWM30061.1 - 8.5 6.1 15.6 23 4.7 10.8 1.7 1 1 0 1 1 1 0 Membrane-associating domain DUF4149 PF13664.1 EWM30063.1 - 2.6e-25 88.3 2.3 2.6e-25 88.3 1.6 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4149) DUF2620 PF10941.3 EWM30063.1 - 0.018 15.0 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF2620 PIRT PF15099.1 EWM30063.1 - 0.04 13.1 0.1 0.098 11.8 0.1 1.7 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family DUF4212 PF13937.1 EWM30063.1 - 1.2 9.2 4.4 2.8 8.0 3.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4212) DUF2305 PF10230.4 EWM30064.1 - 6.3e-08 32.3 0.0 2.4e-07 30.4 0.0 1.9 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 EWM30064.1 - 3.3e-05 23.8 4.2 4.4e-05 23.4 2.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM30064.1 - 0.01 15.6 0.0 0.016 14.9 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 EWM30064.1 - 0.088 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein ROK PF00480.15 EWM30065.1 - 4.8e-18 65.6 1.8 7.1e-18 65.0 1.2 1.2 1 0 0 1 1 1 1 ROK family TPP_enzyme_N PF02776.13 EWM30065.1 - 0.14 11.5 0.3 0.23 10.9 0.2 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Synaptobrevin PF00957.16 EWM30066.1 - 7.4e-28 95.9 0.2 1.1e-27 95.4 0.1 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EWM30066.1 - 2.8e-17 62.0 0.0 4.7e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF1833 PF08875.6 EWM30066.1 - 0.016 14.3 0.2 0.025 13.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1833) Acetyltransf_1 PF00583.19 EWM30067.1 - 4.3e-12 45.8 0.0 7.8e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EWM30067.1 - 1.1e-07 31.9 0.0 1.8e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EWM30067.1 - 6.2e-06 25.8 0.0 2.6e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.1 EWM30067.1 - 0.00019 21.4 0.0 0.00041 20.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EWM30067.1 - 0.05 13.7 0.0 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EWM30067.1 - 0.051 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.1 EWM30067.1 - 0.12 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Kinetochor_Ybp2 PF08568.5 EWM30068.1 - 1.7e-07 29.9 0.0 2.1e-06 26.3 0.0 2.2 2 1 0 2 2 2 1 Uncharacterised protein family, YAP/Alf4/glomulin DUF2205 PF10224.4 EWM30068.1 - 0.043 13.3 0.1 0.095 12.2 0.1 1.5 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) Chloroa_b-bind PF00504.16 EWM30071.1 - 2.1e-31 109.3 0.0 3e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Myb_DNA-bind_6 PF13921.1 EWM30072.1 - 6.8e-25 86.9 6.0 1e-16 60.7 0.4 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EWM30072.1 - 1.3e-23 82.7 5.1 4.6e-12 45.7 0.0 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.3 EWM30072.1 - 0.00036 20.3 1.9 0.13 12.1 0.1 2.1 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 EWM30072.1 - 0.00046 19.9 1.6 0.03 14.1 0.3 3.0 2 1 0 2 2 2 1 Rap1 Myb domain RD3 PF14473.1 EWM30072.1 - 0.092 12.2 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 RD3 protein Myb_DNA-bind_4 PF13837.1 EWM30072.1 - 2.9 8.0 8.1 18 5.5 1.4 3.3 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Amidohydro_1 PF01979.15 EWM30074.1 - 2.3e-60 204.9 0.9 3.6e-60 204.3 0.6 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 EWM30074.1 - 5.4e-47 158.9 0.5 1.1e-46 157.9 0.3 1.5 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.13 EWM30074.1 - 1.2e-39 134.3 0.1 3.1e-39 132.9 0.0 1.8 1 0 0 1 1 1 1 Urease, gamma subunit Urease_beta PF00699.15 EWM30074.1 - 1.1e-38 131.0 0.0 2e-37 127.0 0.0 2.4 2 0 0 2 2 2 1 Urease beta subunit Amidohydro_3 PF07969.6 EWM30074.1 - 1.1e-06 28.0 0.2 9.8e-06 25.0 0.0 2.3 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 EWM30074.1 - 6.6e-06 25.8 3.3 1.1e-05 25.1 1.3 2.2 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_4 PF13147.1 EWM30074.1 - 0.00047 20.2 0.8 0.7 9.8 0.0 3.0 3 0 0 3 3 3 2 Amidohydrolase MFS_1 PF07690.11 EWM30075.1 - 8.8e-12 44.4 10.2 1.2e-11 43.9 7.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EWM30075.1 - 0.1 11.1 11.3 0.11 11.0 6.8 1.7 1 1 0 1 1 1 0 Sugar (and other) transporter MFS_1 PF07690.11 EWM30076.1 - 8.8e-12 44.4 10.2 1.2e-11 43.9 7.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EWM30076.1 - 0.1 11.1 11.3 0.11 11.0 6.8 1.7 1 1 0 1 1 1 0 Sugar (and other) transporter TauD PF02668.11 EWM30077.1 - 1.7e-55 188.4 0.0 2.1e-55 188.2 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 EWM30078.1 - 1e-20 73.8 7.3 1.3e-20 73.4 5.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EWM30078.1 - 0.019 13.1 2.1 0.027 12.6 1.5 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) DUF443 PF04276.7 EWM30078.1 - 0.55 9.6 9.2 0.015 14.6 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Dsh_C PF12316.3 EWM30078.1 - 5.7 7.0 10.4 9 6.3 7.2 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal MFS_1 PF07690.11 EWM30079.1 - 1.3e-20 73.4 7.4 1.7e-20 73.0 5.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EWM30079.1 - 0.015 13.4 2.2 0.022 12.9 1.5 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) DUF443 PF04276.7 EWM30079.1 - 0.93 8.8 9.5 0.025 14.0 1.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Dsh_C PF12316.3 EWM30079.1 - 5.7 7.0 10.4 9 6.3 7.2 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal SMI1_KNR4 PF09346.5 EWM30080.1 - 0.0066 16.4 0.0 0.03 14.3 0.0 2.0 2 0 0 2 2 2 1 SMI1 / KNR4 family (SUKH-1) Nop14 PF04147.7 EWM30082.1 - 0.01 13.8 38.6 0.012 13.5 26.7 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 EWM30082.1 - 0.48 9.4 30.5 0.67 8.9 21.1 1.2 1 0 0 1 1 1 0 BUD22 Zip PF02535.17 EWM30082.1 - 4 6.3 5.8 5.3 5.9 4.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2722 PF10846.3 EWM30082.1 - 6.2 5.7 7.4 7.3 5.4 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SprA-related PF12118.3 EWM30084.1 - 0.00079 18.8 40.3 0.0012 18.2 27.9 1.2 1 0 0 1 1 1 1 SprA-related family SAGA-Tad1 PF12767.2 EWM30084.1 - 0.062 12.9 25.6 0.099 12.2 17.8 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF4045 PF13254.1 EWM30084.1 - 0.064 12.5 20.0 0.1 11.8 13.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) RR_TM4-6 PF06459.7 EWM30084.1 - 0.066 13.0 21.4 0.094 12.6 14.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Spore_coat_CotO PF14153.1 EWM30084.1 - 0.17 11.3 29.7 0.25 10.7 20.6 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Hid1 PF12722.2 EWM30084.1 - 0.33 8.5 24.0 0.43 8.2 16.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ycf1 PF05758.7 EWM30084.1 - 0.6 7.7 23.1 0.77 7.4 16.0 1.0 1 0 0 1 1 1 0 Ycf1 PAT1 PF09770.4 EWM30084.1 - 0.72 8.0 73.2 0.037 12.2 41.1 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 SAPS PF04499.10 EWM30084.1 - 0.85 8.1 17.5 1.1 7.8 12.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4175 PF13779.1 EWM30084.1 - 5.4 4.5 63.5 7.3 4.1 44.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) AUX_IAA PF02309.11 EWM30084.1 - 5.6 6.6 20.3 8.4 6.0 14.1 1.2 1 0 0 1 1 1 0 AUX/IAA family CDC45 PF02724.9 EWM30084.1 - 6 4.7 22.1 7.7 4.4 15.3 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 EWM30084.1 - 8.2 5.7 28.8 12 5.2 20.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) AvrE PF11725.3 EWM30084.1 - 8.2 3.2 24.4 10 3.0 16.9 1.0 1 0 0 1 1 1 0 Pathogenicity factor LMBR1 PF04791.11 EWM30084.1 - 8.8 4.7 6.5 11 4.4 4.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein ALMT PF11744.3 EWM30085.1 - 0.088 11.4 1.1 0.12 10.9 0.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter UPF0197 PF05251.7 EWM30085.1 - 0.16 12.3 0.7 0.57 10.5 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0197) RDD PF06271.7 EWM30086.1 - 0.14 12.0 1.9 0.2 11.5 1.3 1.4 1 1 0 1 1 1 0 RDD family Pyridoxal_deC PF00282.14 EWM30087.1 - 2.4e-37 128.2 0.0 3.5e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF1768 PF08719.6 EWM30087.1 - 0.15 11.8 0.5 15 5.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1768) Pyr_redox_2 PF07992.9 EWM30088.1 - 2.2e-21 76.6 0.0 3e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EWM30088.1 - 0.00033 21.0 0.1 0.0014 18.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EWM30088.1 - 0.00037 20.6 0.0 0.72 9.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EWM30088.1 - 0.0096 15.9 0.7 0.018 15.0 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Glucodextran_B PF09136.5 EWM30088.1 - 0.028 14.5 0.1 0.058 13.5 0.0 1.5 2 0 0 2 2 2 0 Glucodextranase, domain B DAO PF01266.19 EWM30088.1 - 0.068 12.0 0.0 0.17 10.7 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_10 PF13460.1 EWM30088.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Pyridoxal_deC PF00282.14 EWM30089.1 - 1.6e-11 43.3 0.0 1.9e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Pyr_redox PF00070.22 EWM30090.1 - 1.2e-06 28.8 0.0 2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EWM30090.1 - 0.052 13.4 0.0 0.1 12.4 0.0 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Spc7 PF08317.6 EWM30093.1 - 5.1 5.6 34.2 3.5 6.2 5.6 3.1 2 1 1 3 3 3 0 Spc7 kinetochore protein Dynamin_N PF00350.18 EWM30094.1 - 1.1e-23 83.8 0.0 1.6e-19 70.3 0.0 2.8 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EWM30094.1 - 1.6e-14 53.8 0.0 5.3e-14 52.1 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EWM30094.1 - 3.8e-07 29.7 0.0 1.8e-06 27.5 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EWM30094.1 - 7.8e-05 23.1 0.0 0.00018 22.0 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EWM30094.1 - 0.0033 16.8 0.0 0.064 12.6 0.0 2.5 1 1 1 2 2 2 1 Ras family FeoB_N PF02421.13 EWM30094.1 - 0.011 15.0 0.2 2.2 7.5 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B IIGP PF05049.8 EWM30094.1 - 0.039 12.7 0.3 0.13 11.0 0.0 1.9 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.18 EWM30095.1 - 1.3e-23 83.6 0.0 2e-11 43.9 0.0 2.5 1 1 1 2 2 2 2 Dynamin family MMR_HSR1 PF01926.18 EWM30095.1 - 1.4e-14 53.9 0.0 4.8e-14 52.3 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EWM30095.1 - 3.6e-07 29.8 0.0 1.5e-06 27.7 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EWM30095.1 - 6.9e-05 23.3 0.0 0.00016 22.1 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EWM30095.1 - 0.0028 17.0 0.0 0.058 12.7 0.0 2.5 1 1 1 2 2 2 1 Ras family FeoB_N PF02421.13 EWM30095.1 - 0.01 15.1 0.2 2 7.6 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B IIGP PF05049.8 EWM30095.1 - 0.038 12.8 0.3 0.12 11.1 0.0 1.9 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) FA_desaturase PF00487.19 EWM30097.1 - 2.7e-16 59.7 4.0 4.8e-16 58.9 2.7 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 EWM30097.1 - 3.4e-15 54.9 0.3 5.8e-15 54.2 0.2 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) DnaJ PF00226.26 EWM30098.1 - 1.2e-22 79.4 3.9 1.8e-22 78.8 2.7 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EWM30098.1 - 2.2e-08 33.8 0.2 2.4e-07 30.5 0.1 2.2 2 0 0 2 2 2 1 DnaJ C terminal domain Lipase_3 PF01764.20 EWM30099.1 - 3.6e-06 26.6 0.6 3e-05 23.6 0.3 2.2 2 1 0 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EWM30099.1 - 0.00078 19.3 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2048 PF09752.4 EWM30099.1 - 0.0011 17.9 0.1 0.0017 17.2 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) Abhydrolase_5 PF12695.2 EWM30099.1 - 0.0011 18.7 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EWM30099.1 - 0.023 14.2 0.2 0.049 13.2 0.1 1.4 1 0 0 1 1 1 0 PGAP1-like protein Thioesterase PF00975.15 EWM30099.1 - 0.053 13.7 0.2 0.13 12.4 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain Esterase PF00756.15 EWM30099.1 - 0.07 12.5 0.1 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 Putative esterase UPF0051 PF01458.12 EWM30100.1 - 4.2e-56 189.9 0.1 6.1e-56 189.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) UCR_Fe-S_N PF10399.4 EWM30100.1 - 0.11 11.7 2.2 0.47 9.6 1.4 2.2 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal adh_short PF00106.20 EWM30101.1 - 7.2e-15 55.2 0.0 1.2e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EWM30101.1 - 1.9e-05 24.5 0.0 3.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EWM30101.1 - 0.0012 18.5 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Glyco_hydro_18 PF00704.23 EWM30102.1 - 1.8e-21 76.9 0.0 3e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GHL15 PF14885.1 EWM30102.1 - 0.033 14.4 0.2 0.15 12.2 0.0 2.0 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase family 15 UAA PF08449.6 EWM30103.1 - 1.2e-55 188.5 13.7 1.5e-55 188.2 9.5 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EWM30103.1 - 0.003 17.6 20.1 0.026 14.5 5.7 3.1 2 1 1 3 3 3 2 EamA-like transporter family TPT PF03151.11 EWM30103.1 - 0.61 9.7 22.1 0.016 14.8 6.7 2.9 3 0 0 3 3 3 0 Triose-phosphate Transporter family Biotin_lipoyl PF00364.17 EWM30104.1 - 4.7e-20 70.9 1.0 6e-20 70.6 0.7 1.1 1 0 0 1 1 1 1 Biotin-requiring enzyme QRPTase_N PF02749.11 EWM30104.1 - 0.014 15.1 0.0 0.03 14.1 0.0 1.6 1 1 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain GCV_H PF01597.14 EWM30104.1 - 0.037 13.7 0.0 0.047 13.3 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage H-protein Biotin_lipoyl_2 PF13533.1 EWM30104.1 - 0.04 13.5 0.0 6.3 6.5 0.0 2.2 1 1 1 2 2 2 0 Biotin-lipoyl like Erythro_esteras PF05139.9 EWM30105.1 - 4.5e-91 305.6 1.5 5.2e-91 305.4 1.1 1.0 1 0 0 1 1 1 1 Erythromycin esterase Erythro_esteras PF05139.9 EWM30106.1 - 2.3e-96 323.0 1.2 3.2e-96 322.5 0.8 1.2 1 0 0 1 1 1 1 Erythromycin esterase IF-2B PF01008.12 EWM30107.1 - 1.9e-77 260.0 0.2 2.5e-77 259.6 0.1 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family APH PF01636.18 EWM30107.1 - 1e-16 61.4 0.1 3e-16 59.8 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EWM30107.1 - 0.0027 17.2 0.0 0.0046 16.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase tRNA_U5-meth_tr PF05958.6 EWM30108.1 - 0.00012 20.8 0.0 0.00037 19.2 0.0 1.7 2 0 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase MethyltransfD12 PF02086.10 EWM30108.1 - 0.019 14.4 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase TPR_11 PF13414.1 EWM30109.1 - 3.2e-18 65.1 2.5 2.8e-09 36.4 0.0 3.9 2 2 1 4 4 4 3 TPR repeat TPR_1 PF00515.23 EWM30109.1 - 5.8e-15 54.1 0.0 0.0024 17.3 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EWM30109.1 - 4.5e-12 44.9 4.2 0.0043 16.8 0.0 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 EWM30109.1 - 1.1e-09 38.0 7.8 0.00028 20.7 1.9 3.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 EWM30109.1 - 2.3e-06 27.3 3.4 0.97 9.3 0.7 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EWM30109.1 - 1.9e-05 25.1 22.7 0.21 12.2 0.1 5.0 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EWM30109.1 - 0.0032 17.1 0.1 11 6.0 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 EWM30109.1 - 0.0052 16.0 1.9 13 5.1 0.1 3.4 3 0 0 3 3 3 0 SHNi-TPR DegS PF05384.6 EWM30109.1 - 0.0073 15.5 0.2 0.012 14.7 0.1 1.3 1 0 0 1 1 1 1 Sensor protein DegS TPR_14 PF13428.1 EWM30109.1 - 0.013 16.0 15.4 1.1 10.0 0.2 5.6 3 2 3 6 6 6 0 Tetratricopeptide repeat DUF3856 PF12968.2 EWM30109.1 - 0.015 15.1 0.9 5.8 6.7 0.0 3.0 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_7 PF13176.1 EWM30109.1 - 0.03 14.1 4.0 4.1 7.4 0.1 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat SnoaL_2 PF12680.2 EWM30109.1 - 0.05 14.0 2.0 0.054 13.9 0.2 1.9 2 0 0 2 2 2 0 SnoaL-like domain TPR_17 PF13431.1 EWM30109.1 - 0.076 13.2 0.2 42 4.6 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.4 EWM30109.1 - 0.17 11.8 4.0 7.1 6.5 0.0 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EWM30109.1 - 0.49 10.9 9.1 3.4 8.3 0.1 4.7 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 EWM30109.1 - 1.2 9.7 7.9 19 6.0 0.4 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 EWM30109.1 - 2.2 8.3 8.8 17 5.5 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat PAPS_reduct PF01507.14 EWM30110.1 - 5.8e-06 26.2 0.0 0.00019 21.3 0.0 2.0 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family Syja_N PF02383.13 EWM30111.1 - 3.3e-65 219.9 0.0 4.1e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Cupin_1 PF00190.17 EWM30112.1 - 0.071 12.5 0.0 1.4 8.3 0.0 2.3 2 0 0 2 2 2 0 Cupin DUF3813 PF12758.2 EWM30112.1 - 0.071 13.2 0.2 0.24 11.5 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) PAPS_reduct PF01507.14 EWM30113.1 - 1.5e-12 47.7 0.0 2.5e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family TT_ORF2a PF08197.6 EWM30113.1 - 0.038 13.7 0.1 0.087 12.6 0.1 1.6 1 0 0 1 1 1 0 pORF2a truncated protein ORC6 PF05460.8 EWM30114.1 - 0.059 12.4 0.0 0.077 12.0 0.0 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Pkinase PF00069.20 EWM30117.1 - 1.4e-33 116.1 0.0 4.2e-26 91.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EWM30117.1 - 3.1e-19 69.0 0.0 1.7e-11 43.7 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 EWM30118.1 - 1.4e-33 116.1 0.0 4.2e-26 91.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EWM30118.1 - 3.1e-19 69.0 0.0 1.7e-11 43.7 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Lactamase_B PF00753.22 EWM30120.1 - 9.2e-21 74.3 0.2 1.4e-20 73.7 0.2 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EWM30120.1 - 7e-05 22.4 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EWM30121.1 - 1.1e-20 74.1 0.2 1.7e-20 73.5 0.2 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EWM30121.1 - 8.3e-05 22.2 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain SET PF00856.23 EWM30122.1 - 0.048 13.9 0.0 1.1 9.6 0.0 2.4 1 1 0 1 1 1 0 SET domain DUF418 PF04235.7 EWM30124.1 - 0.0049 16.5 1.9 0.0086 15.7 1.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF418) DUF4061 PF13270.1 EWM30124.1 - 0.053 13.6 2.5 0.1 12.7 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) FA_desaturase PF00487.19 EWM30124.1 - 0.067 12.6 1.5 0.11 11.8 1.1 1.3 1 0 0 1 1 1 0 Fatty acid desaturase Med11 PF10280.4 EWM30125.1 - 0.061 13.3 0.5 0.061 13.3 0.4 1.7 2 0 0 2 2 2 0 Mediator complex protein MFS_1 PF07690.11 EWM30127.1 - 3.1e-21 75.4 25.8 3.1e-21 75.4 17.9 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4407 PF14362.1 EWM30129.1 - 0.0025 16.8 4.5 0.005 15.8 3.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) HALZ PF02183.13 EWM30129.1 - 0.012 15.3 0.1 0.032 13.9 0.1 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper CtIP_N PF10482.4 EWM30129.1 - 0.035 13.8 0.1 0.072 12.8 0.1 1.5 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain DUF4201 PF13870.1 EWM30129.1 - 0.19 11.1 1.9 0.35 10.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) bZIP_1 PF00170.16 EWM30129.1 - 0.29 11.1 0.1 0.29 11.1 0.1 2.9 4 0 0 4 4 4 0 bZIP transcription factor DUF2383 PF09537.5 EWM30129.1 - 0.62 10.3 3.2 0.71 10.1 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF2383) NYD-SP28 PF14772.1 EWM30129.1 - 3.3 7.8 8.2 0.63 10.1 0.7 2.9 3 0 0 3 3 3 0 Sperm tail Lar_restr_allev PF14354.1 EWM30130.1 - 0.0014 18.9 0.1 0.0031 17.7 0.1 1.6 1 0 0 1 1 1 1 Restriction alleviation protein Lar zf-CHC2 PF01807.15 EWM30130.1 - 0.14 11.7 0.8 1.4 8.5 0.5 2.1 1 1 1 2 2 2 0 CHC2 zinc finger Transglut_core PF01841.14 EWM30131.1 - 8.2e-11 42.1 0.4 2.8e-10 40.3 0.2 2.0 2 0 0 2 2 2 1 Transglutaminase-like superfamily Rad4 PF03835.10 EWM30131.1 - 5.2e-07 29.1 0.0 1e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain FOLN PF09289.5 EWM30132.1 - 4.6 7.1 5.9 0.58 10.0 0.9 1.9 2 0 0 2 2 2 0 Follistatin/Osteonectin-like EGF domain MCM_N PF14551.1 EWM30133.1 - 6.3e-16 58.9 0.0 1e-15 58.3 0.0 1.3 1 1 0 1 1 1 1 MCM N-terminal domain AAA_25 PF13481.1 EWM30134.1 - 6.1e-22 77.9 0.0 1.7e-21 76.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain Toprim_4 PF13662.1 EWM30134.1 - 6.6e-10 38.8 0.0 2.4e-09 37.0 0.0 1.9 2 0 0 2 2 2 1 Toprim domain AAA_22 PF13401.1 EWM30134.1 - 1.7e-08 34.6 0.0 2.5e-07 30.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain Toprim_3 PF13362.1 EWM30134.1 - 2.6e-08 34.0 0.0 7e-08 32.6 0.0 1.7 2 0 0 2 2 1 1 Toprim domain Toprim_2 PF13155.1 EWM30134.1 - 1.6e-07 31.5 0.0 3.3e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Toprim-like KaiC PF06745.8 EWM30134.1 - 7.7e-06 25.1 0.0 1.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 KaiC DnaB_C PF03796.10 EWM30134.1 - 0.00021 20.2 0.0 0.00052 18.9 0.0 1.7 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_29 PF13555.1 EWM30134.1 - 0.00075 18.9 1.4 0.0032 16.9 0.2 2.4 3 0 0 3 3 2 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EWM30134.1 - 0.0012 19.0 0.1 0.0024 18.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_24 PF13479.1 EWM30134.1 - 0.0014 18.2 0.0 0.0041 16.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain UPF0079 PF02367.12 EWM30134.1 - 0.0016 18.0 0.0 0.0063 16.1 0.1 1.9 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_16 PF13191.1 EWM30134.1 - 0.0027 17.6 0.1 0.011 15.6 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.1 EWM30134.1 - 0.0028 18.0 0.2 0.0052 17.1 0.1 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EWM30134.1 - 0.0029 17.2 0.7 0.0051 16.4 0.1 1.7 2 0 0 2 2 1 1 NACHT domain T2SE PF00437.15 EWM30134.1 - 0.0033 16.3 0.0 0.0052 15.7 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein IstB_IS21 PF01695.12 EWM30134.1 - 0.0064 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF258 PF03193.11 EWM30134.1 - 0.0097 15.1 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 EWM30134.1 - 0.017 15.0 0.0 0.065 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EWM30134.1 - 0.023 15.4 0.3 0.072 13.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EWM30134.1 - 0.028 14.1 0.0 0.062 13.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain cobW PF02492.14 EWM30134.1 - 0.035 13.5 0.3 0.089 12.2 0.2 1.6 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 EWM30134.1 - 0.05 13.5 0.3 0.19 11.6 0.1 1.9 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EWM30134.1 - 0.071 12.1 0.2 0.19 10.7 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.1 EWM30134.1 - 0.11 12.3 0.9 0.4 10.5 0.1 2.1 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EWM30134.1 - 0.12 12.1 0.3 0.27 10.9 0.0 1.7 2 0 0 2 2 2 0 NTPase AAA_18 PF13238.1 EWM30134.1 - 0.14 12.4 0.1 0.41 10.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain Toprim PF01751.17 EWM30134.1 - 0.15 12.0 0.0 0.74 9.8 0.0 2.1 1 1 0 1 1 1 0 Toprim domain ResIII PF04851.10 EWM30134.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit MCM PF00493.18 EWM30135.1 - 7.3e-08 31.5 0.0 8.8e-08 31.3 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family SNAP PF14938.1 EWM30136.1 - 1.6e-38 132.4 9.1 1.9e-38 132.2 6.3 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 EWM30136.1 - 4.4e-07 29.7 4.6 1.2e-05 25.1 1.0 2.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EWM30136.1 - 2.9e-06 26.6 5.7 0.82 9.6 0.1 4.5 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EWM30136.1 - 2.5e-05 23.6 8.7 0.026 14.1 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EWM30136.1 - 3.5e-05 23.4 7.1 0.35 10.9 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 EWM30136.1 - 0.00028 20.4 9.1 0.0017 17.9 1.5 3.0 1 1 2 3 3 3 2 TPR repeat TPR_8 PF13181.1 EWM30136.1 - 0.0015 18.1 9.2 0.14 11.9 0.0 4.4 4 1 1 5 5 5 2 Tetratricopeptide repeat RPN7 PF10602.4 EWM30136.1 - 0.025 13.9 1.8 0.2 11.0 0.0 2.6 1 1 1 3 3 3 0 26S proteasome subunit RPN7 TPR_16 PF13432.1 EWM30136.1 - 0.052 14.2 4.1 15 6.4 0.4 3.5 1 1 2 3 3 3 0 Tetratricopeptide repeat DUF2989 PF11207.3 EWM30136.1 - 0.099 12.0 0.1 0.14 11.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2989) Cu2_monooxygen PF01082.15 EWM30136.1 - 0.13 12.2 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, N-terminal domain TPR_6 PF13174.1 EWM30136.1 - 0.16 12.4 6.6 31 5.3 0.0 4.8 3 2 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 EWM30136.1 - 0.2 11.5 12.6 1 9.2 0.1 3.7 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain NSF PF02071.15 EWM30136.1 - 0.89 10.3 0.2 0.89 10.3 0.1 6.7 7 3 1 8 8 6 0 Aromatic-di-Alanine (AdAR) repeat TPR_19 PF14559.1 EWM30136.1 - 1.4 9.2 4.4 6.1 7.2 0.6 3.1 1 1 1 2 2 2 0 Tetratricopeptide repeat Thiolase_N PF00108.18 EWM30137.1 - 3e-96 321.4 0.1 4.1e-96 321.0 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EWM30137.1 - 5.4e-43 145.3 2.8 3e-42 142.9 0.3 2.4 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EWM30137.1 - 0.00013 21.5 1.8 0.00013 21.5 1.3 2.8 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EWM30137.1 - 0.059 13.0 5.5 0.38 10.4 0.0 3.3 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III MCM PF00493.18 EWM30138.1 - 8e-64 215.5 0.0 1.4e-63 214.7 0.0 1.3 1 1 0 1 1 1 1 MCM2/3/5 family PBP1_TM PF14812.1 EWM30138.1 - 0.25 11.6 5.9 0.088 13.1 1.8 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MCM PF00493.18 EWM30139.1 - 3.4e-57 193.7 0.3 3.9e-56 190.2 0.0 2.2 2 1 0 2 2 2 2 MCM2/3/5 family DUF2009 PF09418.5 EWM30140.1 - 1.4e-22 80.1 0.9 1.7e-22 79.8 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) DUF2009 PF09418.5 EWM30141.1 - 6.6e-133 443.8 0.0 7.9e-133 443.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) POTRA_2 PF08479.6 EWM30141.1 - 0.12 12.0 0.1 4.4 7.0 0.0 2.4 2 0 0 2 2 2 0 POTRA domain, ShlB-type Mito_fiss_reg PF05308.6 EWM30141.1 - 0.44 9.8 5.8 0.9 8.8 4.0 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator Trp_Tyr_perm PF03222.8 EWM30142.1 - 1.8e-72 244.3 17.3 2.6e-72 243.8 12.0 1.1 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Aa_trans PF01490.13 EWM30142.1 - 3e-05 22.6 4.8 3e-05 22.6 3.3 1.9 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein GFO_IDH_MocA PF01408.17 EWM30143.1 - 9.7e-23 80.9 0.3 2.1e-22 79.8 0.2 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 EWM30143.1 - 0.0033 17.7 0.1 0.0064 16.7 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 EWM30143.1 - 0.018 15.3 0.2 0.032 14.6 0.1 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Sulfatase PF00884.18 EWM30144.1 - 5.5e-11 42.2 0.8 2.2e-09 36.9 0.5 2.4 1 1 0 1 1 1 1 Sulfatase DUF229 PF02995.12 EWM30144.1 - 8.1e-07 27.8 0.0 1.7e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4149 PF13664.1 EWM30144.1 - 0.0093 16.0 2.7 0.11 12.5 0.6 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4149) NARP1 PF12569.3 EWM30147.1 - 3.2e-129 432.0 12.9 5.9e-126 421.2 6.2 4.0 2 2 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 EWM30147.1 - 8.5e-11 41.3 13.8 0.00094 18.7 0.0 6.0 7 0 0 7 7 7 4 TPR repeat TPR_19 PF14559.1 EWM30147.1 - 5.1e-08 33.1 21.8 0.0044 17.3 0.3 7.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.1 EWM30147.1 - 6.4e-07 29.8 38.7 0.066 13.9 9.1 9.5 8 2 0 8 8 8 1 Tetratricopeptide repeat TPR_2 PF07719.12 EWM30147.1 - 2.3e-05 23.9 28.3 0.062 13.2 0.8 8.5 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_1 PF00515.23 EWM30147.1 - 0.00013 21.4 12.8 0.19 11.4 0.1 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 EWM30147.1 - 0.00017 21.8 33.1 0.023 15.3 1.3 9.5 8 1 2 10 10 10 2 Tetratricopeptide repeat TPR_7 PF13176.1 EWM30147.1 - 0.00086 18.9 8.7 1.1 9.2 0.0 5.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 EWM30147.1 - 0.017 14.8 11.1 15 5.6 0.1 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 EWM30147.1 - 0.023 14.6 24.3 0.22 11.4 0.1 6.5 6 1 1 7 7 7 0 Tetratricopeptide repeat Pkinase PF00069.20 EWM30150.1 - 3.3e-28 98.5 0.4 6e-28 97.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM30150.1 - 2.1e-11 43.3 0.0 2.1e-11 43.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase 2OG-FeII_Oxy_2 PF13532.1 EWM30151.1 - 3.3e-16 59.6 0.0 7.1e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EWM30151.1 - 7.9e-07 29.2 0.7 2.4e-06 27.7 0.0 2.1 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EWM30151.1 - 0.0035 17.8 0.1 0.032 14.7 0.0 2.6 3 1 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily DUF826 PF05696.6 EWM30151.1 - 0.15 12.2 0.9 4.7 7.4 0.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF826) DUF2749 PF10907.3 EWM30152.1 - 0.11 12.4 1.3 0.45 10.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) Ribosomal_L28 PF00830.14 EWM30153.1 - 7.4e-17 60.9 4.7 9.6e-17 60.5 3.2 1.1 1 0 0 1 1 1 1 Ribosomal L28 family U-box PF04564.10 EWM30154.1 - 2.4e-21 75.4 0.1 3.1e-21 75.0 0.1 1.1 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.3 EWM30154.1 - 0.043 13.3 0.0 0.15 11.6 0.0 1.8 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Nop14 PF04147.7 EWM30154.1 - 0.13 10.1 12.6 0.11 10.3 8.7 1.2 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EWM30154.1 - 0.31 9.4 13.0 0.3 9.5 9.0 1.2 1 0 0 1 1 1 0 Daxx Family Spore_coat_CotO PF14153.1 EWM30154.1 - 0.38 10.1 9.2 0.53 9.7 6.4 1.2 1 0 0 1 1 1 0 Spore coat protein CotO CDC45 PF02724.9 EWM30154.1 - 1.2 7.1 7.5 1.2 7.1 5.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 EWM30154.1 - 1.9 7.8 11.2 3.2 7.0 7.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Cyclin_N PF00134.18 EWM30155.1 - 8.6e-14 51.1 0.1 4e-12 45.8 0.0 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain FA_desaturase PF00487.19 EWM30156.1 - 1.9e-24 86.5 15.2 1.9e-24 86.5 10.6 2.0 1 1 1 2 2 2 1 Fatty acid desaturase ATP_sub_h PF10775.4 EWM30156.1 - 0.14 11.8 0.0 13 5.6 0.0 2.3 2 0 0 2 2 2 0 ATP synthase complex subunit h PMM PF03332.8 EWM30159.1 - 2e-102 341.4 0.2 2.4e-102 341.1 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EWM30159.1 - 2.4e-08 33.9 0.0 4.9e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EWM30159.1 - 0.037 13.3 0.0 0.24 10.6 0.0 1.9 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Ank_2 PF12796.2 EWM30160.1 - 8.9e-37 125.3 3.8 8.4e-17 61.2 0.1 4.2 3 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 EWM30160.1 - 5.1e-30 101.7 19.4 5.5e-05 22.7 0.0 7.5 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.1 EWM30160.1 - 5.1e-28 96.4 8.9 1.3e-06 28.4 0.0 7.3 3 3 4 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM30160.1 - 3.7e-27 91.6 1.9 0.00037 20.4 0.0 7.5 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 EWM30160.1 - 4.6e-26 90.7 5.5 7.3e-07 29.5 0.0 6.2 4 1 3 7 7 7 6 Ankyrin repeats (many copies) TPR_11 PF13414.1 EWM30160.1 - 1.2e-15 56.9 3.6 4.6e-13 48.5 0.1 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EWM30160.1 - 1.2e-08 34.2 4.1 0.0072 16.1 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EWM30160.1 - 1e-06 28.0 0.6 0.41 10.3 0.4 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EWM30160.1 - 1.9e-06 28.3 11.7 0.00057 20.4 0.3 3.6 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EWM30160.1 - 6.4e-06 26.4 2.0 0.0097 16.2 1.0 3.6 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EWM30160.1 - 0.0031 17.5 0.1 2 8.8 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EWM30160.1 - 0.0032 17.5 0.0 0.0082 16.2 0.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EWM30160.1 - 0.024 14.5 6.8 0.11 12.4 0.1 3.3 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EWM30160.1 - 0.46 11.2 9.9 3 8.7 0.3 5.0 2 1 2 4 4 4 0 Tetratricopeptide repeat Alg6_Alg8 PF03155.10 EWM30161.1 - 2.3e-108 363.0 6.9 3e-108 362.6 4.8 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family CDC50 PF03381.10 EWM30162.1 - 2.5e-79 266.3 0.0 6.5e-79 264.9 0.0 1.6 1 1 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family zf-met PF12874.2 EWM30163.1 - 1.8e-06 27.9 1.0 3.1e-06 27.1 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EWM30163.1 - 2.9e-06 27.2 0.8 5.1e-06 26.4 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.7 EWM30163.1 - 0.00024 20.6 1.0 0.00045 19.6 0.7 1.5 1 0 0 1 1 1 1 U1 zinc finger CCDC84 PF14968.1 EWM30163.1 - 0.0017 17.9 0.3 0.0025 17.3 0.2 1.3 1 0 0 1 1 1 1 Coiled coil protein 84 DUF501 PF04417.7 EWM30163.1 - 0.22 11.3 1.6 0.28 11.0 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF501) DUF1777 PF08648.7 EWM30163.1 - 0.95 9.1 8.6 0.067 12.9 2.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) Metallophos PF00149.23 EWM30166.1 - 1.6e-25 89.6 0.3 2.7e-25 88.9 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Sec2p PF06428.6 EWM30166.1 - 0.0012 18.6 0.9 0.0022 17.8 0.7 1.4 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p Metallophos_2 PF12850.2 EWM30166.1 - 0.0015 18.4 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SlyX PF04102.7 EWM30166.1 - 0.044 14.1 1.4 0.1 12.9 1.0 1.5 1 0 0 1 1 1 0 SlyX Syntaphilin PF15290.1 EWM30166.1 - 0.068 12.6 0.2 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp Med4 PF10018.4 EWM30166.1 - 0.1 11.9 0.5 0.27 10.6 0.2 1.7 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 SET PF00856.23 EWM30169.1 - 2.3e-12 47.5 0.1 6.4e-10 39.5 0.0 3.4 3 1 0 3 3 3 1 SET domain BLVR PF06375.6 EWM30169.1 - 0.65 9.8 17.9 0.81 9.5 4.6 2.5 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) Methyltransf_23 PF13489.1 EWM30170.1 - 2.3e-13 50.2 0.0 3.9e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM30170.1 - 3.6e-11 43.4 0.0 8.3e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM30170.1 - 2.4e-10 40.7 0.0 4.2e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM30170.1 - 1.4e-06 28.5 0.0 3.1e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EWM30170.1 - 2.6e-06 27.9 0.0 4.8e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM30170.1 - 3.6e-06 26.6 0.0 5.4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EWM30170.1 - 0.0073 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EWM30170.1 - 0.0078 16.2 1.4 0.031 14.3 0.9 2.0 1 1 0 1 1 1 1 Methyltransferase domain Pcc1 PF09341.5 EWM30171.1 - 6.2e-17 61.4 0.2 8.1e-17 61.0 0.2 1.2 1 0 0 1 1 1 1 Transcription factor Pcc1 GIT1_C PF12205.3 EWM30171.1 - 0.061 13.1 0.1 0.18 11.6 0.1 1.8 1 1 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term HEAT PF02985.17 EWM30172.1 - 3.1e-37 123.2 47.2 0.0015 18.4 0.0 23.7 28 0 0 28 28 26 8 HEAT repeat HEAT_2 PF13646.1 EWM30172.1 - 1.4e-30 105.3 78.5 3.3e-06 27.2 0.1 18.2 11 5 8 19 19 19 10 HEAT repeats HEAT_EZ PF13513.1 EWM30172.1 - 1.4e-24 85.8 91.1 0.00066 20.0 0.1 23.5 18 5 8 27 27 25 8 HEAT-like repeat CLASP_N PF12348.3 EWM30172.1 - 2.3e-16 59.8 0.0 2.9e-05 23.5 0.0 8.0 8 1 0 8 8 8 3 CLASP N terminal Vac14_Fab1_bd PF12755.2 EWM30172.1 - 2.6e-16 59.8 0.0 0.29 11.5 0.0 9.2 9 2 1 10 10 8 5 Vacuolar 14 Fab1-binding region ParcG PF10274.4 EWM30172.1 - 6.2e-10 39.2 0.0 0.92 9.3 0.0 6.0 6 0 0 6 6 6 3 Parkin co-regulated protein Ipi1_N PF12333.3 EWM30172.1 - 1.2e-09 38.0 2.4 10 6.1 0.0 10.1 11 2 1 12 12 10 0 Rix1 complex component involved in 60S ribosome maturation Adaptin_N PF01602.15 EWM30172.1 - 5.3e-08 31.6 3.2 0.027 12.8 0.0 6.5 6 2 0 7 7 7 2 Adaptin N terminal region Cnd1 PF12717.2 EWM30172.1 - 1.1e-05 25.3 0.0 6.1 6.6 0.0 5.9 5 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 DUF3554 PF12074.3 EWM30172.1 - 7.6e-05 22.2 0.0 0.13 11.6 0.0 5.2 5 1 0 5 5 5 1 Domain of unknown function (DUF3554) DUF2454 PF10521.4 EWM30172.1 - 0.0003 19.8 0.2 9.6 5.1 0.0 4.6 4 0 0 4 4 4 1 Protein of unknown function (DUF2454) Cnd3 PF12719.2 EWM30172.1 - 0.08 11.9 0.7 5.8 5.8 0.1 3.5 4 0 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain Cohesin_HEAT PF12765.2 EWM30172.1 - 0.86 9.6 24.2 6.3 6.8 0.0 9.5 10 0 0 10 10 9 0 HEAT repeat associated with sister chromatid cohesion MOR2-PAG1_N PF14222.1 EWM30172.1 - 2.5 6.6 0.1 30 3.1 0.0 2.5 3 0 0 3 3 3 0 Cell morphogenesis N-terminal Orbi_VP3 PF01700.11 EWM30172.1 - 6.8 3.9 0.1 9.8 3.4 0.1 1.1 1 0 0 1 1 1 0 Orbivirus VP3 (T2) protein Acyl-CoA_dh_1 PF00441.19 EWM30173.1 - 2.6e-47 160.6 4.5 3.9e-47 160.1 3.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EWM30173.1 - 1.4e-25 90.0 0.1 2.5e-25 89.2 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EWM30173.1 - 4.4e-21 74.1 0.0 8.7e-21 73.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EWM30173.1 - 3.1e-20 72.7 3.1 7e-20 71.6 1.8 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 EWM30173.1 - 0.017 15.4 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal URO-D PF01208.12 EWM30174.1 - 1.3e-74 251.2 0.1 1.5e-74 250.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Voldacs PF03517.8 EWM30175.1 - 2.9e-22 78.9 0.0 4.8e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling DUF1084 PF06454.6 EWM30176.1 - 3.2e-07 29.6 15.7 6.1e-07 28.7 10.7 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) Herpes_LMP1 PF05297.6 EWM30176.1 - 0.04 12.8 6.2 0.0069 15.3 0.8 2.1 1 1 1 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) DUF3783 PF12646.2 EWM30176.1 - 0.14 11.9 0.2 2.1 8.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3783) GBP PF02263.14 EWM30177.1 - 6.9e-14 51.5 0.0 1.7e-13 50.2 0.0 1.7 1 1 0 1 1 1 1 Guanylate-binding protein, N-terminal domain FlxA PF14282.1 EWM30177.1 - 3.5 7.6 8.6 22 5.0 0.9 3.6 2 1 1 3 3 3 0 FlxA-like protein DUF760 PF05542.6 EWM30178.1 - 8.9e-20 70.6 0.0 1.8e-10 40.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF760) zf-C3HC4_3 PF13920.1 EWM30179.1 - 0.013 15.1 0.6 0.021 14.4 0.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EWM30179.1 - 0.025 14.6 1.2 0.038 14.0 0.8 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EWM30179.1 - 0.03 14.0 0.7 0.046 13.4 0.5 1.2 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 EWM30179.1 - 0.064 12.9 0.7 0.1 12.3 0.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1180 PF06679.7 EWM30179.1 - 0.17 11.7 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) LysM PF01476.15 EWM30180.1 - 1.8e-05 24.5 0.0 0.026 14.4 0.0 2.6 2 0 0 2 2 2 2 LysM domain PDZ PF00595.19 EWM30180.1 - 0.0074 16.4 0.1 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) LysM PF01476.15 EWM30181.1 - 1.3e-05 24.9 0.0 0.022 14.6 0.0 2.5 2 0 0 2 2 2 2 LysM domain PDZ PF00595.19 EWM30181.1 - 0.0059 16.7 0.1 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) zinc_ribbon_6 PF14599.1 EWM30182.1 - 1.5e-20 72.7 0.1 1.5e-20 72.7 0.0 2.5 3 0 0 3 3 3 1 Zinc-ribbon zf-CHY PF05495.7 EWM30182.1 - 8.2e-14 51.5 20.6 8.2e-14 51.5 14.3 4.5 3 1 1 4 4 4 2 CHY zinc finger zf-RING_2 PF13639.1 EWM30182.1 - 1.1e-07 31.5 9.5 1.1e-07 31.5 6.6 3.8 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 EWM30182.1 - 6.1e-07 29.0 7.5 6.1e-07 29.0 5.2 4.8 3 2 1 4 4 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EWM30182.1 - 1.2e-05 25.1 5.2 1.2e-05 25.1 3.6 5.4 2 1 3 5 5 5 1 Zinc finger, C3HC4 type (RING finger) Hemerythrin PF01814.18 EWM30182.1 - 0.00035 20.7 3.5 0.0068 16.5 0.6 2.5 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain DUF2267 PF10025.4 EWM30182.1 - 0.049 13.6 0.1 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) GDA1_CD39 PF01150.12 EWM30184.1 - 2.9e-64 217.1 0.0 2.5e-63 214.0 0.0 2.1 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF3042 PF11240.3 EWM30184.1 - 0.19 11.5 0.7 0.53 10.1 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Pex19 PF04614.7 EWM30185.1 - 4.4e-33 114.9 2.6 1.3e-32 113.3 1.8 1.7 1 1 0 1 1 1 1 Pex19 protein family DUF2890 PF11081.3 EWM30185.1 - 0.028 14.4 2.0 0.039 14.0 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Herpes_capsid PF06112.6 EWM30185.1 - 0.21 11.6 4.8 0.46 10.5 3.4 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DRIM PF07539.7 EWM30186.1 - 2.1e-22 79.0 0.0 8.5e-22 77.0 0.0 2.1 1 0 0 1 1 1 1 Down-regulated in metastasis HEAT PF02985.17 EWM30186.1 - 6.1e-06 25.8 4.3 0.0015 18.4 0.1 5.4 4 0 0 4 4 4 1 HEAT repeat Patatin PF01734.17 EWM30187.1 - 1.9e-29 103.0 0.5 6.2e-29 101.3 0.0 2.1 2 0 0 2 2 2 1 Patatin-like phospholipase Orbi_VP6 PF01516.11 EWM30187.1 - 0.094 11.7 0.5 0.69 8.9 0.0 2.3 2 1 0 3 3 3 0 Orbivirus helicase VP6 CIA30 PF08547.7 EWM30188.1 - 6.8e-27 94.2 0.0 8.7e-27 93.8 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) 2OG-FeII_Oxy_3 PF13640.1 EWM30189.1 - 0.00034 21.0 0.1 0.0011 19.4 0.1 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RRM_1 PF00076.17 EWM30191.1 - 4.8e-06 26.1 0.0 8.1e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM30191.1 - 8.8e-05 22.4 0.0 0.00016 21.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM30191.1 - 0.0017 18.1 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF525 PF04379.9 EWM30192.1 - 3.6e-09 36.4 0.1 7.9e-09 35.3 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF525) APC_CDC26 PF10471.4 EWM30192.1 - 0.45 11.2 8.6 10 6.9 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Complex1_LYR PF05347.10 EWM30192.1 - 2.3 8.0 5.4 3.6 7.4 1.6 2.3 2 0 0 2 2 2 0 Complex 1 protein (LYR family) Asp_Arg_Hydrox PF05118.10 EWM30193.1 - 3e-29 101.9 0.0 4.3e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase NAD_synthase PF02540.12 EWM30195.1 - 1.1e-06 27.7 0.0 0.00016 20.6 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Asn_synthase PF00733.16 EWM30195.1 - 4.2e-06 26.4 0.0 6.6e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.11 EWM30195.1 - 0.0013 17.3 0.0 0.044 12.3 0.0 2.2 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.8 EWM30195.1 - 0.15 11.3 0.0 8.6 5.5 0.0 2.3 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC NAP PF00956.13 EWM30196.1 - 1.6e-29 102.7 0.1 3e-29 101.8 0.1 1.4 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) Phage_Mu_Gam PF07352.7 EWM30196.1 - 0.025 14.0 0.2 0.04 13.4 0.1 1.3 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein DUF3541 PF12060.3 EWM30196.1 - 0.1 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3541) NAP PF00956.13 EWM30197.1 - 1.5e-29 102.8 0.1 2.8e-29 101.9 0.1 1.4 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) Phage_Mu_Gam PF07352.7 EWM30197.1 - 0.024 14.1 0.2 0.038 13.4 0.1 1.3 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein DUF3541 PF12060.3 EWM30197.1 - 0.097 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3541) Saccharop_dh PF03435.13 EWM30198.1 - 7.9e-15 54.7 0.0 1.1e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Choline_kinase PF01633.15 EWM30199.1 - 1.5e-43 148.8 0.0 2.1e-43 148.3 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EWM30199.1 - 7.6e-19 68.3 0.0 1.7e-14 54.1 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Spb1_C PF07780.7 EWM30200.1 - 1.9e-54 184.4 18.4 1.9e-54 184.4 12.7 4.2 4 1 1 5 5 5 1 Spb1 C-terminal domain FtsJ PF01728.14 EWM30200.1 - 7.6e-53 179.1 0.0 1.4e-52 178.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.3 EWM30200.1 - 1.6e-36 125.1 1.2 1.6e-36 125.1 0.8 4.5 4 1 0 4 4 4 1 Domain of unknown function (DUF3381) DUF148 PF02520.12 EWM30200.1 - 0.0017 18.1 0.3 0.0017 18.1 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function DUF148 DUF111 PF01969.12 EWM30201.1 - 4.2e-114 381.3 0.0 1.9e-113 379.1 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function DUF111 Zip PF02535.17 EWM30201.1 - 0.022 13.7 4.0 0.26 10.2 4.5 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter PCI_Csn8 PF10075.4 EWM30203.1 - 8.3e-15 54.8 0.0 1.4e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EWM30203.1 - 4.8e-11 42.5 0.6 2.6e-10 40.2 0.4 1.9 1 1 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Mpv17_PMP22 PF04117.7 EWM30205.1 - 2e-08 33.7 0.0 4.3e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family FMN_dh PF01070.13 EWM30206.1 - 4.7e-142 473.0 0.8 5.4e-142 472.8 0.6 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.9 EWM30206.1 - 6.3e-05 22.1 0.4 0.026 13.6 0.1 2.6 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 EWM30206.1 - 0.0045 15.9 2.3 0.0098 14.8 0.1 2.5 3 1 1 4 4 4 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EWM30206.1 - 0.016 14.3 0.3 0.033 13.3 0.2 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase TMP-TENI PF02581.12 EWM30206.1 - 0.026 13.6 0.0 0.087 11.9 0.0 1.9 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI Glu_synthase PF01645.12 EWM30206.1 - 0.069 12.0 0.1 0.15 10.9 0.0 1.5 2 0 0 2 2 2 0 Conserved region in glutamate synthase His_biosynth PF00977.16 EWM30206.1 - 0.11 11.8 0.0 1.2 8.3 0.0 2.2 1 1 1 2 2 2 0 Histidine biosynthesis protein DHO_dh PF01180.16 EWM30206.1 - 0.12 11.3 0.1 2.8 6.8 0.0 2.1 1 1 1 2 2 2 0 Dihydroorotate dehydrogenase PDT PF00800.13 EWM30208.1 - 5.4e-58 195.5 0.0 7.2e-57 191.8 0.0 2.6 3 0 0 3 3 3 1 Prephenate dehydratase PDH PF02153.12 EWM30208.1 - 1e-13 50.7 0.0 1.7e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.12 EWM30208.1 - 3.6e-08 33.7 0.0 8.6e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.4 EWM30208.1 - 0.008 15.9 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Rossmann-like domain TrkA_N PF02254.13 EWM30208.1 - 0.059 13.3 0.0 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain Ephrin_lbd PF01404.14 EWM30208.1 - 0.075 12.8 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Ephrin receptor ligand binding domain NAD_binding_2 PF03446.10 EWM30208.1 - 0.09 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.17 EWM30208.1 - 0.15 12.5 0.0 6.9 7.2 0.0 2.6 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold zf-C3HC4 PF00097.20 EWM30209.1 - 8.9e-09 34.8 6.7 8.9e-09 34.8 4.6 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EWM30209.1 - 2.5e-08 33.6 6.3 2.5e-08 33.6 4.4 2.1 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EWM30209.1 - 4.6e-07 29.5 7.4 4.6e-07 29.5 5.1 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EWM30209.1 - 5.1e-07 29.6 7.2 5.1e-07 29.6 5.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EWM30209.1 - 1.7e-06 27.6 15.5 1.4e-05 24.6 4.9 2.5 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_6 PF14835.1 EWM30209.1 - 1.5e-05 24.7 2.4 1.5e-05 24.7 1.6 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EWM30209.1 - 8.2e-05 22.2 5.0 0.00021 20.9 3.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 EWM30209.1 - 0.00015 21.4 7.2 0.00015 21.4 5.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RanBP PF00641.13 EWM30209.1 - 0.0028 16.7 4.0 0.0028 16.7 2.8 2.5 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others zf-rbx1 PF12678.2 EWM30209.1 - 0.0091 16.0 3.7 0.0091 16.0 2.5 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger SAP PF02037.22 EWM30209.1 - 0.01 15.2 0.0 0.023 14.2 0.0 1.6 1 0 0 1 1 1 0 SAP domain zf-Apc11 PF12861.2 EWM30209.1 - 0.024 14.4 1.9 0.024 14.4 1.3 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Ribosomal_L21p PF00829.16 EWM30209.1 - 0.095 12.8 2.9 0.49 10.5 0.5 2.8 1 1 1 2 2 2 0 Ribosomal prokaryotic L21 protein E1-E2_ATPase PF00122.15 EWM30210.1 - 4.3e-51 173.1 0.3 1.2e-50 171.7 0.2 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EWM30210.1 - 4.3e-41 140.4 3.1 4.3e-41 140.4 2.1 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EWM30210.1 - 2.9e-21 76.8 0.0 3.3e-20 73.4 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EWM30210.1 - 3.1e-15 55.3 0.0 8.2e-15 54.0 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EWM30210.1 - 4.1e-14 53.2 0.0 8.4e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EWM30210.1 - 5.3e-11 42.3 0.0 1.1e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EWM30210.1 - 0.0028 17.2 1.0 0.043 13.3 0.4 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Baseplate_J PF04865.9 EWM30210.1 - 0.088 12.1 0.1 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 Baseplate J-like protein UDPGP PF01704.13 EWM30211.1 - 6e-12 44.7 0.0 1e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Ham1p_like PF01725.11 EWM30212.1 - 4.6e-46 156.5 0.0 6.2e-46 156.1 0.0 1.1 1 0 0 1 1 1 1 Ham1 family CBF PF03914.12 EWM30213.1 - 1.3e-19 70.2 0.0 1.3e-19 70.2 0.0 2.6 3 1 0 3 3 3 1 CBF/Mak21 family NOC3p PF07540.6 EWM30213.1 - 5.8e-19 68.1 3.1 5.6e-18 64.9 0.5 3.1 2 1 0 2 2 2 1 Nucleolar complex-associated protein CDC45 PF02724.9 EWM30213.1 - 0.71 7.8 13.2 0.015 13.3 4.2 1.7 2 0 0 2 2 2 0 CDC45-like protein BSP_II PF05432.6 EWM30213.1 - 6 6.0 30.1 0.084 12.1 15.0 2.1 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) NOA36 PF06524.7 EWM30213.1 - 8.4 5.5 11.8 15 4.7 8.2 1.3 1 0 0 1 1 1 0 NOA36 protein PPR_2 PF13041.1 EWM30215.1 - 6.7e-53 176.4 0.0 2.4e-09 36.9 0.0 12.4 7 3 7 14 14 14 10 PPR repeat family PPR PF01535.15 EWM30215.1 - 8e-38 125.8 21.4 0.00041 20.1 0.0 16.2 19 0 0 19 19 19 7 PPR repeat PPR_3 PF13812.1 EWM30215.1 - 1.2e-36 121.9 23.7 0.0045 17.1 0.1 15.7 17 0 0 17 17 17 10 Pentatricopeptide repeat domain PPR_1 PF12854.2 EWM30215.1 - 2.9e-17 61.8 2.9 0.081 12.4 0.0 9.6 10 0 0 10 10 10 4 PPR repeat TPR_14 PF13428.1 EWM30215.1 - 0.0011 19.3 20.5 5.5 7.9 0.2 9.3 8 2 2 10 10 10 1 Tetratricopeptide repeat HRDC PF00570.18 EWM30215.1 - 0.0029 17.2 0.5 0.13 11.9 0.0 3.3 4 0 0 4 4 4 1 HRDC domain Apc3 PF12895.2 EWM30215.1 - 0.12 12.4 8.4 26 5.0 0.0 5.5 5 1 0 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4398 PF14346.1 EWM30215.1 - 0.25 11.4 3.1 9.3 6.3 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) YfiO PF13525.1 EWM30215.1 - 2.1 7.7 3.8 5.5 6.4 0.1 3.3 5 0 0 5 5 5 0 Outer membrane lipoprotein Kinesin PF00225.18 EWM30216.1 - 1.2e-107 359.5 0.0 2.8e-107 358.2 0.0 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bind PF13931.1 EWM30216.1 - 8.5e-05 22.7 0.1 8.5e-05 22.7 0.1 3.8 3 0 0 3 3 3 1 Kinesin-associated microtubule-binding AAA_13 PF13166.1 EWM30216.1 - 0.053 11.9 17.5 0.02 13.4 2.7 3.6 3 1 0 3 3 3 0 AAA domain IFT57 PF10498.4 EWM30216.1 - 0.55 8.9 18.6 0.019 13.6 6.9 2.3 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Med21 PF11221.3 EWM30216.1 - 4.2 7.3 18.7 0.22 11.4 7.0 3.4 2 1 1 3 3 3 0 Subunit 21 of Mediator complex DUF4200 PF13863.1 EWM30216.1 - 9.8 6.1 31.8 0.18 11.7 10.8 4.8 4 1 0 4 4 4 0 Domain of unknown function (DUF4200) RAP PF08373.5 EWM30218.1 - 2.8e-17 62.2 0.0 5.8e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 RAP domain FAST_1 PF06743.10 EWM30218.1 - 4e-05 23.2 0.1 0.02 14.5 0.0 3.6 2 1 2 4 4 4 1 FAST kinase-like protein, subdomain 1 CRAL_TRIO PF00650.15 EWM30219.1 - 4e-21 75.1 0.0 7.9e-21 74.1 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain PH PF00169.24 EWM30219.1 - 1.9e-07 31.2 0.0 3.7e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 PH domain CRAL_TRIO_2 PF13716.1 EWM30219.1 - 0.045 13.6 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Ribosomal_L13 PF00572.13 EWM30220.1 - 4.4e-26 91.4 0.0 8.2e-26 90.5 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L13 Pkinase PF00069.20 EWM30221.1 - 2.6e-65 220.1 0.0 3.6e-65 219.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM30221.1 - 1.2e-42 145.8 0.0 1.6e-42 145.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EWM30221.1 - 1.2e-24 86.4 4.3 7.5e-13 48.6 0.1 2.8 2 0 0 2 2 2 2 P21-Rho-binding domain Kinase-like PF14531.1 EWM30221.1 - 1.8e-07 30.3 0.3 1.5e-05 24.1 0.0 2.6 2 1 1 3 3 3 1 Kinase-like APH PF01636.18 EWM30221.1 - 0.0078 15.9 2.3 0.074 12.7 0.0 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EWM30221.1 - 0.018 14.1 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EWM30221.1 - 0.03 13.1 0.0 0.049 12.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 CRAL_TRIO PF00650.15 EWM30222.1 - 4.2e-32 110.8 0.0 6e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EWM30222.1 - 1.8e-08 34.4 0.0 3.2e-08 33.6 0.0 1.4 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain Clat_adaptor_s PF01217.15 EWM30223.1 - 1.3e-41 141.6 5.1 7.2e-40 135.9 3.6 2.0 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Ribosomal_S30AE PF02482.14 EWM30223.1 - 0.028 14.8 0.0 0.046 14.1 0.0 1.3 1 0 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein PseudoU_synth_1 PF01416.15 EWM30224.1 - 3.3e-22 78.9 0.0 2.5e-10 40.7 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase ORMDL PF04061.9 EWM30225.1 - 3e-32 111.0 4.2 3.6e-32 110.7 2.9 1.1 1 0 0 1 1 1 1 ORMDL family Acyl_transf_3 PF01757.17 EWM30225.1 - 0.081 11.7 8.6 0.13 11.0 6.0 1.5 1 1 0 1 1 1 0 Acyltransferase family Radical_SAM PF04055.16 EWM30226.1 - 1.5e-16 60.9 0.1 1.1e-15 58.2 0.0 2.2 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EWM30226.1 - 2.1e-11 43.6 0.1 7.9e-11 41.8 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EWM30226.1 - 0.0084 16.2 0.2 0.021 14.9 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EWM30226.1 - 0.017 15.2 0.3 0.042 13.9 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EWM30226.1 - 0.039 13.7 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 FR47-like protein Rep_2 PF01719.12 EWM30226.1 - 0.14 11.6 0.0 0.45 9.9 0.0 1.8 2 0 0 2 2 2 0 Plasmid replication protein Peptidase_M16 PF00675.15 EWM30228.1 - 7.6e-19 67.9 0.0 1.4e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EWM30228.1 - 0.00012 21.8 0.0 0.00054 19.6 0.0 2.1 2 1 0 2 2 2 1 Peptidase M16 inactive domain Amino_oxidase PF01593.19 EWM30229.1 - 9.9e-10 38.0 0.0 5.5e-09 35.5 0.0 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EWM30229.1 - 8.1e-09 35.3 0.2 1.8e-08 34.2 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EWM30229.1 - 3.3e-05 24.0 0.2 6.5e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EWM30229.1 - 0.0022 17.0 0.1 0.0041 16.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 EWM30229.1 - 0.0027 16.6 0.1 0.0044 15.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EWM30229.1 - 0.0084 16.0 0.0 0.042 13.7 0.0 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_18 PF12847.2 EWM30229.1 - 0.026 15.0 0.0 6.6 7.3 0.0 2.9 2 1 0 3 3 3 0 Methyltransferase domain Thi4 PF01946.12 EWM30229.1 - 0.028 13.5 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DAO PF01266.19 EWM30229.1 - 0.071 12.0 0.2 0.12 11.2 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EWM30229.1 - 0.16 11.7 0.6 6.1 6.5 0.1 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding ELO PF01151.13 EWM30230.1 - 4e-59 199.9 19.6 5.3e-59 199.5 13.6 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family 2-ph_phosp PF04029.9 EWM30230.1 - 0.022 13.7 0.0 0.056 12.4 0.0 1.6 2 0 0 2 2 2 0 2-phosphosulpholactate phosphatase RNA_pol_Rpb2_6 PF00562.23 EWM30232.1 - 6.9e-114 380.5 0.0 1e-113 380.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EWM30232.1 - 8.2e-51 171.8 0.0 1.3e-50 171.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 EWM30232.1 - 4.1e-29 100.6 0.1 1e-28 99.3 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.11 EWM30232.1 - 2.3e-22 78.5 0.0 4.4e-22 77.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.9 EWM30232.1 - 4.5e-22 78.4 0.0 1.3e-21 76.8 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 EWM30232.1 - 6.4e-20 70.7 0.1 1.5e-19 69.5 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 EWM30232.1 - 6.1e-10 38.9 0.8 2.6e-09 36.8 0.3 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 Peptidase_M41 PF01434.13 EWM30233.1 - 8.4e-72 241.0 0.0 1.5e-71 240.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EWM30233.1 - 1.4e-44 151.5 0.1 7e-44 149.2 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EWM30233.1 - 3.1e-07 30.5 0.0 1.6e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 FtsH Extracellular AAA_5 PF07728.9 EWM30233.1 - 0.00024 20.8 0.1 0.0041 16.8 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EWM30233.1 - 0.00024 21.2 0.0 0.015 15.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EWM30233.1 - 0.00031 21.5 0.0 0.0011 19.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EWM30233.1 - 0.00052 19.7 2.4 0.00064 19.4 0.6 2.0 2 0 0 2 2 1 1 Part of AAA domain TIP49 PF06068.8 EWM30233.1 - 0.0017 17.1 0.1 0.003 16.3 0.1 1.3 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 EWM30233.1 - 0.003 16.6 0.0 0.0095 15.0 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EWM30233.1 - 0.0037 17.2 0.0 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EWM30233.1 - 0.0044 16.9 0.0 0.019 14.8 0.0 2.0 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.1 EWM30233.1 - 0.011 15.6 0.0 0.03 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EWM30233.1 - 0.022 14.6 0.1 0.065 13.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_16 PF13191.1 EWM30233.1 - 0.027 14.4 0.3 0.25 11.3 0.1 2.5 2 1 0 2 2 1 0 AAA ATPase domain IstB_IS21 PF01695.12 EWM30233.1 - 0.028 13.8 0.0 0.066 12.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 EWM30233.1 - 0.077 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EWM30233.1 - 0.14 11.5 1.6 3.5 6.9 0.1 2.7 2 1 1 3 3 3 0 AAA domain DEAD PF00270.24 EWM30234.1 - 5.7e-18 64.9 0.0 1.4e-17 63.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EWM30234.1 - 3.3e-17 62.1 0.0 1.7e-16 59.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HRDC PF00570.18 EWM30234.1 - 7.8e-12 44.7 0.0 2.4e-11 43.1 0.0 1.9 1 0 0 1 1 1 1 HRDC domain HTH_40 PF14493.1 EWM30234.1 - 5.8e-09 36.0 0.0 1.8e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain RQC PF09382.5 EWM30234.1 - 9.4e-05 22.0 0.0 0.00025 20.7 0.0 1.7 1 0 0 1 1 1 1 RQC domain PPR_3 PF13812.1 EWM30236.1 - 1.5e-68 221.4 28.0 1.1e-05 25.2 0.0 20.9 21 0 0 21 21 21 16 Pentatricopeptide repeat domain PPR PF01535.15 EWM30236.1 - 5.7e-68 220.3 34.6 2.1e-06 27.3 0.0 21.6 22 0 0 22 22 22 17 PPR repeat PPR_2 PF13041.1 EWM30236.1 - 1.4e-67 223.4 0.0 2.3e-12 46.6 0.0 18.7 12 3 6 18 18 18 11 PPR repeat family PPR_1 PF12854.2 EWM30236.1 - 7e-26 89.3 12.9 1.1e-05 24.7 0.0 13.6 17 0 0 17 17 17 5 PPR repeat Apc3 PF12895.2 EWM30236.1 - 1e-12 48.0 13.2 0.72 10.0 0.0 9.8 7 2 3 10 10 10 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EWM30236.1 - 3.8e-08 33.2 28.9 11 7.0 0.2 14.0 15 1 1 16 16 13 0 Tetratricopeptide repeat TPR_12 PF13424.1 EWM30236.1 - 1.7e-06 27.8 15.1 0.041 13.8 0.0 9.3 9 3 2 11 11 10 1 Tetratricopeptide repeat TPR_10 PF13374.1 EWM30236.1 - 0.00018 21.3 13.2 28 4.7 0.2 9.7 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_7 PF13176.1 EWM30236.1 - 0.00069 19.2 19.9 12 5.9 0.0 11.3 15 0 0 15 15 15 0 Tetratricopeptide repeat Ank_2 PF12796.2 EWM30236.1 - 0.0076 16.5 1.3 2.4 8.5 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Clathrin PF00637.15 EWM30236.1 - 0.032 13.8 0.2 60 3.2 0.0 5.9 7 1 0 8 8 8 0 Region in Clathrin and VPS TPR_2 PF07719.12 EWM30236.1 - 0.048 13.5 15.6 16 5.7 0.0 9.8 11 1 0 11 11 11 0 Tetratricopeptide repeat RICTOR_V PF14668.1 EWM30236.1 - 0.054 13.4 6.8 3.6 7.5 0.2 4.7 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 Ank_3 PF13606.1 EWM30236.1 - 0.092 13.0 0.1 42 4.7 0.0 4.9 4 0 0 4 4 4 0 Ankyrin repeat BTAD PF03704.12 EWM30236.1 - 0.14 12.4 27.5 0.3 11.3 0.3 6.6 4 2 2 6 6 6 0 Bacterial transcriptional activator domain TPR_6 PF13174.1 EWM30236.1 - 7.5 7.2 20.6 28 5.4 0.0 9.3 14 0 0 14 14 10 0 Tetratricopeptide repeat PPR_2 PF13041.1 EWM30237.1 - 2.9e-102 334.5 24.5 8.4e-14 51.2 0.1 13.6 5 3 10 15 15 15 12 PPR repeat family PPR_3 PF13812.1 EWM30237.1 - 6.5e-99 316.1 0.1 1.8e-07 30.8 0.0 16.4 16 0 0 16 16 16 12 Pentatricopeptide repeat domain PPR PF01535.15 EWM30237.1 - 3.1e-91 293.2 4.8 3.6e-07 29.7 0.0 15.3 15 0 0 15 15 15 12 PPR repeat PPR_1 PF12854.2 EWM30237.1 - 1.4e-89 293.2 0.0 5.1e-08 32.2 0.0 15.1 15 0 0 15 15 15 13 PPR repeat TPR_14 PF13428.1 EWM30237.1 - 7.7e-25 85.1 3.3 0.43 11.3 0.0 12.5 11 2 2 13 13 12 4 Tetratricopeptide repeat TPR_7 PF13176.1 EWM30237.1 - 9.6e-14 50.0 3.6 0.26 11.1 0.0 9.2 9 1 1 10 10 10 3 Tetratricopeptide repeat TPR_12 PF13424.1 EWM30237.1 - 1.1e-13 50.9 5.1 0.13 12.1 0.0 7.3 5 1 3 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 EWM30237.1 - 6.4e-12 45.8 0.4 2.5 8.8 0.0 7.6 4 3 5 10 10 10 2 Tetratricopeptide repeat TPR_19 PF14559.1 EWM30237.1 - 2.2e-10 40.7 0.3 1.2 9.4 0.0 7.5 8 1 0 8 8 7 1 Tetratricopeptide repeat TPR_4 PF07721.9 EWM30237.1 - 5.5e-10 38.7 0.2 6.5 7.4 0.0 8.8 9 0 0 9 9 9 0 Tetratricopeptide repeat Clathrin PF00637.15 EWM30237.1 - 5.5e-08 32.5 0.0 0.057 13.0 0.0 5.5 4 1 2 6 6 6 2 Region in Clathrin and VPS TPR_10 PF13374.1 EWM30237.1 - 1e-07 31.6 10.5 1.7 8.6 0.0 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_15 PF13429.1 EWM30237.1 - 3.5e-07 29.5 0.0 1.1 8.1 0.0 5.0 3 1 2 5 5 5 2 Tetratricopeptide repeat DUF3366 PF11846.3 EWM30237.1 - 5.7e-07 29.5 7.6 1 9.1 0.0 7.2 4 1 2 7 7 7 2 Domain of unknown function (DUF3366) ECSIT PF06239.6 EWM30237.1 - 9.5e-07 27.9 0.0 1.5 7.5 0.0 5.6 2 2 1 4 4 4 1 Evolutionarily conserved signalling intermediate in Toll pathway TPR_2 PF07719.12 EWM30237.1 - 0.00015 21.3 11.6 33 4.7 0.0 8.6 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_11 PF13414.1 EWM30237.1 - 0.00027 20.5 5.0 17 5.1 0.3 6.4 5 2 1 6 6 6 0 TPR repeat TPR_6 PF13174.1 EWM30237.1 - 0.00096 19.4 3.6 27 5.5 0.0 7.0 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 EWM30237.1 - 0.0075 15.9 4.8 7.1 6.6 0.0 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF2765 PF10963.3 EWM30237.1 - 0.016 15.1 4.5 33 4.5 0.0 5.9 3 2 4 7 7 7 0 Protein of unknown function (DUF2765) IgG_binding_B PF01378.12 EWM30237.1 - 0.023 14.5 0.2 0.2 11.4 0.0 2.8 3 0 0 3 3 3 0 B domain Ank_4 PF13637.1 EWM30237.1 - 0.092 13.2 0.0 3.7 8.1 0.0 3.4 4 0 0 4 4 3 0 Ankyrin repeats (many copies) CMV_1a_C PF12503.3 EWM30237.1 - 0.11 12.2 0.5 10 5.8 0.0 3.3 3 0 0 3 3 3 0 Cucumber mosaic virus 1a protein C terminal TPR_17 PF13431.1 EWM30237.1 - 3.9 7.8 11.0 16 6.0 0.2 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat PPR_2 PF13041.1 EWM30238.1 - 6.6e-102 333.3 24.9 8e-14 51.3 0.1 13.7 5 3 10 15 15 15 12 PPR repeat family PPR_3 PF13812.1 EWM30238.1 - 3.1e-99 317.1 0.1 1.7e-07 30.9 0.0 16.3 16 0 0 16 16 16 12 Pentatricopeptide repeat domain PPR PF01535.15 EWM30238.1 - 1.5e-91 294.1 4.8 3.4e-07 29.7 0.0 15.3 15 0 0 15 15 15 12 PPR repeat PPR_1 PF12854.2 EWM30238.1 - 7.2e-90 294.1 0.0 4.9e-08 32.3 0.0 15.1 15 0 0 15 15 15 13 PPR repeat TPR_14 PF13428.1 EWM30238.1 - 4.5e-25 85.8 3.4 0.41 11.4 0.0 12.5 11 2 2 13 13 12 4 Tetratricopeptide repeat TPR_7 PF13176.1 EWM30238.1 - 6.6e-14 50.5 3.6 0.25 11.2 0.0 9.2 9 1 1 10 10 10 3 Tetratricopeptide repeat TPR_12 PF13424.1 EWM30238.1 - 8.5e-14 51.2 5.2 0.13 12.2 0.0 7.3 5 1 3 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 EWM30238.1 - 4.3e-12 46.3 0.3 2.4 8.9 0.0 7.7 4 3 5 10 10 10 2 Tetratricopeptide repeat TPR_19 PF14559.1 EWM30238.1 - 1.6e-10 41.1 0.4 1.2 9.5 0.0 7.6 8 1 0 8 8 7 1 Tetratricopeptide repeat TPR_4 PF07721.9 EWM30238.1 - 3.8e-10 39.2 0.2 6.2 7.5 0.0 8.9 9 0 0 9 9 9 0 Tetratricopeptide repeat Clathrin PF00637.15 EWM30238.1 - 4.3e-08 32.8 0.0 0.054 13.0 0.0 5.5 4 1 2 6 6 6 2 Region in Clathrin and VPS TPR_10 PF13374.1 EWM30238.1 - 7.1e-08 32.1 10.5 1.6 8.7 0.0 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_15 PF13429.1 EWM30238.1 - 2.8e-07 29.8 0.0 1.1 8.2 0.0 5.0 3 1 2 5 5 5 2 Tetratricopeptide repeat DUF3366 PF11846.3 EWM30238.1 - 4.7e-07 29.8 7.7 1 9.1 0.0 7.2 4 1 2 7 7 7 2 Domain of unknown function (DUF3366) ECSIT PF06239.6 EWM30238.1 - 7.4e-07 28.2 0.0 1.5 7.6 0.0 5.7 2 2 3 6 6 6 1 Evolutionarily conserved signalling intermediate in Toll pathway TPR_11 PF13414.1 EWM30238.1 - 1.5e-05 24.5 1.4 17 5.1 0.3 6.5 6 1 0 6 6 6 0 TPR repeat TPR_2 PF07719.12 EWM30238.1 - 0.0001 21.9 11.6 31 4.8 0.0 8.7 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_6 PF13174.1 EWM30238.1 - 0.0007 19.8 3.6 26 5.5 0.0 7.1 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 EWM30238.1 - 0.0042 16.7 4.3 6.8 6.7 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF2765 PF10963.3 EWM30238.1 - 0.014 15.3 4.7 32 4.5 0.0 6.0 3 2 4 7 7 7 0 Protein of unknown function (DUF2765) IgG_binding_B PF01378.12 EWM30238.1 - 0.024 14.4 0.2 0.19 11.5 0.0 2.7 3 0 0 3 3 3 0 B domain Ank_4 PF13637.1 EWM30238.1 - 0.079 13.4 0.0 3.6 8.2 0.0 3.5 4 0 0 4 4 3 0 Ankyrin repeats (many copies) CMV_1a_C PF12503.3 EWM30238.1 - 0.093 12.4 0.5 10 5.9 0.0 3.3 3 0 0 3 3 3 0 Cucumber mosaic virus 1a protein C terminal TPR_17 PF13431.1 EWM30238.1 - 3.1 8.2 11.0 15 6.0 0.2 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat SNF2_N PF00176.18 EWM30239.1 - 4.4e-63 212.8 0.0 8.4e-63 211.9 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EWM30239.1 - 2.1e-15 56.3 0.0 5.9e-15 54.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EWM30239.1 - 1.9e-13 49.9 0.1 3e-13 49.2 0.1 1.2 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF1087 PF06465.8 EWM30239.1 - 2.7e-05 24.0 1.9 7.4e-05 22.5 0.3 2.6 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1087) DUF1086 PF06461.6 EWM30239.1 - 4.3e-05 23.3 0.0 0.00014 21.7 0.0 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) CHDCT2 PF08074.6 EWM30239.1 - 0.009 15.7 1.0 3.1 7.5 0.3 2.7 2 0 0 2 2 2 2 CHDCT2 (NUC038) domain SGT1 PF07093.6 EWM30240.1 - 1.3e-86 291.2 0.0 1.9e-86 290.7 0.0 1.2 1 0 0 1 1 1 1 SGT1 protein Spt5_N PF11942.3 EWM30240.1 - 0.015 15.8 5.1 0.015 15.8 3.6 3.5 2 1 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Gln-synt_C PF00120.19 EWM30243.1 - 5.8e-55 186.2 0.0 1.2e-31 109.7 0.0 2.2 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain RAP PF08373.5 EWM30244.1 - 1.9e-06 27.5 0.0 5.3e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 RAP domain FAST_1 PF06743.10 EWM30244.1 - 2.3e-05 24.0 0.9 12 5.7 0.0 6.1 4 3 3 7 7 7 4 FAST kinase-like protein, subdomain 1 Aldo_ket_red PF00248.16 EWM30245.1 - 4.4e-05 22.4 0.0 7.3e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family PQ-loop PF04193.9 EWM30246.1 - 5.2e-31 105.9 13.2 4.3e-17 61.4 4.5 3.6 2 1 1 3 3 3 3 PQ loop repeat DUF202 PF02656.10 EWM30246.1 - 1.3 9.3 4.3 1.8 8.8 0.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF202) PRP38_assoc PF12871.2 EWM30247.1 - 0.32 11.5 9.9 0.15 12.6 1.8 2.1 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term MMR_HSR1 PF01926.18 EWM30248.1 - 2.8e-20 72.4 0.0 4.4e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase KH_2 PF07650.12 EWM30248.1 - 1.1e-15 56.8 0.0 1.9e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 KH domain GTP_EFTU PF00009.22 EWM30248.1 - 3.3e-09 36.4 0.0 5.6e-07 29.1 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EWM30248.1 - 3.3e-07 29.7 0.0 7.5e-07 28.5 0.0 1.5 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EWM30248.1 - 4.1e-07 29.9 1.0 0.00075 19.3 0.4 2.3 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 EWM30248.1 - 1.7e-06 28.5 0.0 4.5e-06 27.1 0.0 1.7 2 0 0 2 2 1 1 Miro-like protein AIG1 PF04548.11 EWM30248.1 - 7.5e-05 21.9 0.0 0.00037 19.6 0.0 1.9 2 0 0 2 2 2 1 AIG1 family DUF258 PF03193.11 EWM30248.1 - 0.00042 19.5 0.1 0.00072 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 EWM30248.1 - 0.0027 17.1 0.0 0.011 15.2 0.0 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 EWM30248.1 - 0.0083 15.6 0.2 0.31 10.5 0.0 2.2 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Ras PF00071.17 EWM30248.1 - 0.015 14.7 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 Ras family MobB PF03205.9 EWM30248.1 - 0.045 13.4 0.1 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.5 EWM30248.1 - 0.054 12.7 0.0 0.14 11.3 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_25 PF13481.1 EWM30248.1 - 0.055 12.8 0.0 0.08 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EWM30248.1 - 0.076 13.1 0.0 0.17 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain Sirohm_synth_M PF14824.1 EWM30249.1 - 0.026 13.4 0.1 0.052 12.5 0.0 1.4 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central Cyto_heme_lyase PF01265.12 EWM30250.1 - 3e-68 230.2 0.0 5.1e-68 229.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase PWI PF01480.12 EWM30252.1 - 1.5e-15 57.0 0.2 3.3e-15 55.9 0.2 1.6 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.17 EWM30252.1 - 9.6e-09 34.7 0.0 1.9e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM30252.1 - 0.0037 17.2 0.0 0.0085 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM30252.1 - 0.0088 15.8 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC2_membrane PF01061.19 EWM30253.1 - 3.2e-38 131.0 11.5 4.4e-38 130.5 8.0 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EWM30253.1 - 6.8e-20 71.7 0.0 1.2e-19 70.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 EWM30253.1 - 9.9e-06 24.8 8.4 9.9e-06 24.8 5.8 1.8 1 1 1 2 2 2 1 ABC-2 family transporter protein DUF258 PF03193.11 EWM30253.1 - 7.2e-05 22.0 0.0 0.00013 21.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EWM30253.1 - 0.00033 20.1 0.1 0.0033 16.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EWM30253.1 - 0.00043 19.7 0.1 0.0012 18.3 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EWM30253.1 - 0.0018 18.3 0.1 1.1 9.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EWM30253.1 - 0.0029 16.8 0.1 0.62 9.2 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EWM30253.1 - 0.005 16.8 0.0 0.012 15.5 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 EWM30253.1 - 0.021 14.9 0.2 0.1 12.7 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.1 EWM30253.1 - 0.039 13.8 0.0 0.095 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EWM30253.1 - 0.048 13.0 0.1 0.099 12.0 0.1 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_17 PF13207.1 EWM30253.1 - 0.067 14.0 0.0 0.18 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EWM30253.1 - 0.072 13.2 0.0 0.17 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EWM30253.1 - 0.085 13.1 0.0 0.52 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC2_membrane_2 PF12679.2 EWM30253.1 - 0.66 8.7 6.3 0.66 8.7 0.5 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein Prenyltransf PF01255.14 EWM30254.1 - 0.008 15.3 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Fumerase PF05681.9 EWM30255.1 - 1.7e-89 299.5 0.0 2.3e-89 299.0 0.0 1.2 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Fumerase_C PF05683.7 EWM30255.1 - 1.1e-79 266.3 0.0 1.7e-79 265.7 0.0 1.3 1 0 0 1 1 1 1 Fumarase C-terminus DUF2183 PF09949.4 EWM30256.1 - 9e-05 22.3 0.0 0.00019 21.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Sulfotransfer_2 PF03567.9 EWM30257.1 - 1.3e-05 25.0 0.1 0.00025 20.8 0.1 2.2 1 1 0 1 1 1 1 Sulfotransferase family AAA PF00004.24 EWM30258.1 - 3.9e-40 137.1 0.1 1.2e-39 135.4 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EWM30258.1 - 1.3e-08 34.6 0.2 6.6e-08 32.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EWM30258.1 - 5.7e-08 32.8 0.0 1.7e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EWM30258.1 - 4.5e-05 23.6 0.1 0.00061 19.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EWM30258.1 - 0.0001 21.4 0.0 0.00053 19.0 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 EWM30258.1 - 0.00022 20.8 0.2 0.0023 17.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EWM30258.1 - 0.0005 20.0 0.7 0.0031 17.5 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EWM30258.1 - 0.0014 18.4 0.2 0.0041 16.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 EWM30258.1 - 0.0017 18.2 0.0 0.0072 16.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EWM30258.1 - 0.0019 17.3 0.1 0.0038 16.4 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EWM30258.1 - 0.0035 16.7 0.1 0.0068 15.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 EWM30258.1 - 0.0046 17.7 1.2 0.022 15.5 0.1 2.6 2 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EWM30258.1 - 0.0062 16.2 0.0 0.89 9.2 0.0 2.5 1 1 1 2 2 2 1 Archaeal ATPase AAA_19 PF13245.1 EWM30258.1 - 0.0063 16.2 0.3 0.023 14.4 0.2 1.9 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 EWM30258.1 - 0.0083 15.2 0.5 0.02 14.0 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin DUF1192 PF06698.6 EWM30258.1 - 0.0087 15.8 1.6 0.022 14.5 1.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) AAA_25 PF13481.1 EWM30258.1 - 0.019 14.3 2.4 0.035 13.4 0.1 2.4 2 1 1 3 3 3 0 AAA domain Sigma54_activat PF00158.21 EWM30258.1 - 0.03 13.8 0.1 0.15 11.5 0.1 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.8 EWM30258.1 - 0.031 13.1 0.0 0.06 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.7 EWM30258.1 - 0.032 13.9 0.3 0.15 11.6 0.1 2.1 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 EWM30258.1 - 0.062 13.2 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EWM30258.1 - 0.065 12.0 0.1 0.24 10.2 0.0 1.9 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_18 PF13238.1 EWM30258.1 - 0.076 13.3 2.3 0.097 12.9 0.0 2.5 2 2 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EWM30258.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase GrpE PF01025.14 EWM30258.1 - 0.63 9.5 6.7 1.1 8.7 4.0 1.9 2 0 0 2 2 2 0 GrpE KaiC PF06745.8 EWM30258.1 - 0.66 9.0 0.0 0.66 9.0 0.0 2.6 3 0 0 3 3 3 0 KaiC RRM_1 PF00076.17 EWM30260.1 - 4.9e-30 102.9 0.0 2.5e-15 55.8 0.0 4.4 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM30260.1 - 4.4e-18 65.0 0.1 2e-09 37.3 0.0 3.5 3 1 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM30260.1 - 4e-16 58.5 0.0 8e-09 35.2 0.0 3.8 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EWM30260.1 - 0.015 15.0 0.1 0.19 11.4 0.0 2.6 2 0 0 2 2 2 0 Limkain b1 HSP90 PF00183.13 EWM30260.1 - 0.044 12.1 4.0 0.063 11.6 2.7 1.1 1 0 0 1 1 1 0 Hsp90 protein IMPDH PF00478.20 EWM30261.1 - 4.2e-131 437.0 6.1 4.9e-131 436.8 4.2 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EWM30261.1 - 1.1e-15 57.1 0.2 2.4e-06 27.2 0.0 2.7 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 EWM30261.1 - 1.4e-09 37.5 3.9 5.5e-08 32.3 2.1 2.2 2 0 0 2 2 2 1 Nitronate monooxygenase FMN_dh PF01070.13 EWM30261.1 - 3.8e-06 26.0 1.6 6.5e-06 25.2 1.1 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 EWM30261.1 - 0.00042 19.6 3.9 0.0027 17.0 1.6 2.6 2 1 0 2 2 2 1 Histidine biosynthesis protein NanE PF04131.9 EWM30261.1 - 0.003 16.5 1.0 0.011 14.7 0.7 2.0 1 1 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase ThiG PF05690.9 EWM30261.1 - 0.0032 16.6 5.5 0.0037 16.3 1.7 2.7 3 1 1 4 4 4 1 Thiazole biosynthesis protein ThiG Aldolase PF01081.14 EWM30261.1 - 0.015 14.4 0.5 0.042 13.0 0.0 2.0 2 0 0 2 2 2 0 KDPG and KHG aldolase DUF561 PF04481.7 EWM30261.1 - 0.037 12.9 2.0 0.82 8.5 0.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF561) B12-binding PF02310.14 EWM30261.1 - 0.039 13.8 0.1 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 B12 binding domain DHO_dh PF01180.16 EWM30261.1 - 0.11 11.3 4.9 0.88 8.4 0.7 2.4 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase AA_permease_2 PF13520.1 EWM30262.1 - 4.1e-30 104.6 32.7 8.5e-30 103.6 22.6 1.5 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EWM30262.1 - 4.3e-05 22.0 15.2 4.3e-05 22.0 10.5 2.4 2 0 0 2 2 2 1 Amino acid permease DUF4281 PF14108.1 EWM30263.1 - 2.5e-33 114.9 4.1 5e-33 113.9 2.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4281) HrpE PF06188.7 EWM30263.1 - 0.17 11.6 15.8 2.6 7.7 4.3 2.7 1 1 1 2 2 2 0 HrpE/YscL/FliH and V-type ATPase subunit E ARGLU PF15346.1 EWM30263.1 - 0.24 11.1 9.8 0.38 10.5 6.8 1.2 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 DivIVA PF05103.8 EWM30263.1 - 0.77 9.8 20.6 2.1 8.3 4.4 2.9 2 1 1 3 3 3 0 DivIVA protein ATP-synt_B PF00430.13 EWM30263.1 - 3.6 7.4 28.8 1.4 8.7 8.0 2.8 2 1 2 4 4 4 0 ATP synthase B/B' CF(0) 2Fe-2S_thioredx PF01257.14 EWM30264.1 - 1.3e-57 193.4 0.1 1.9e-57 192.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Plasmod_Pvs28 PF06247.6 EWM30264.1 - 0.11 12.1 0.3 0.14 11.6 0.2 1.1 1 0 0 1 1 1 0 Plasmodium ookinete surface protein Pvs28 PMI_typeI PF01238.16 EWM30265.1 - 1.4e-103 346.7 0.0 1.7e-103 346.4 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 EWM30265.1 - 0.00023 20.5 0.0 2.6 7.6 0.0 4.1 3 1 0 3 3 3 2 Cupin domain Cupin_1 PF00190.17 EWM30265.1 - 0.0046 16.4 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 Cupin DUF2348 PF09807.4 EWM30267.1 - 9.6e-14 51.0 0.4 1.6e-08 34.0 0.4 2.5 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2348) TPT PF03151.11 EWM30268.1 - 2.3e-16 59.8 10.5 2.3e-16 59.8 7.3 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EWM30268.1 - 4e-05 23.6 31.2 0.00072 19.5 4.9 2.2 2 0 0 2 2 2 2 EamA-like transporter family IBR PF01485.16 EWM30270.1 - 1.2e-07 31.4 10.0 1.2e-07 31.4 6.9 4.0 3 1 0 3 3 3 1 IBR domain Acetyltransf_1 PF00583.19 EWM30271.1 - 0.0013 18.7 0.0 0.0031 17.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.1 EWM30271.1 - 0.01 16.4 0.0 0.027 15.0 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EWM30271.1 - 0.049 13.7 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain OrfB_Zn_ribbon PF07282.6 EWM30271.1 - 0.44 10.2 2.3 0.82 9.3 1.6 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Methyltransf_5 PF01795.14 EWM30272.1 - 2.3e-78 263.6 0.0 3.7e-78 262.9 0.0 1.3 1 1 0 1 1 1 1 MraW methylase family Methyltransf_26 PF13659.1 EWM30272.1 - 0.0011 18.9 0.1 0.011 15.7 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM30272.1 - 0.0047 17.3 0.1 0.15 12.5 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EWM30272.1 - 0.014 14.5 0.0 0.15 11.1 0.0 2.0 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EWM30272.1 - 0.02 15.4 0.0 0.21 12.2 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 EWM30272.1 - 0.029 13.9 0.0 0.58 9.7 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.2 EWM30273.1 - 1e-15 58.2 0.7 1.3e-10 41.8 0.0 2.7 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.1 EWM30273.1 - 3.9e-10 39.5 0.0 9.3e-10 38.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM30273.1 - 1.7e-08 34.8 0.0 2e-06 28.1 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM30273.1 - 6.3e-08 33.0 0.0 1.5e-06 28.6 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM30273.1 - 0.00024 21.4 0.1 0.0018 18.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EWM30273.1 - 0.00093 18.9 0.1 0.0032 17.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Spermine_synth PF01564.12 EWM30273.1 - 0.0056 15.6 0.0 0.02 13.8 0.0 1.8 2 0 0 2 2 2 1 Spermine/spermidine synthase Complex1_LYR PF05347.10 EWM30274.1 - 2.4e-08 33.6 0.5 3.1e-08 33.2 0.3 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EWM30274.1 - 1.3e-07 31.6 0.2 1.5e-07 31.5 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like DUF3110 PF11360.3 EWM30274.1 - 0.048 13.4 0.0 0.057 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3110) Beta-lactamase PF00144.19 EWM30274.1 - 0.11 11.4 0.1 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase ABC_membrane PF00664.18 EWM30275.1 - 4e-48 164.2 10.0 4.8e-25 88.4 1.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EWM30275.1 - 1.5e-42 145.1 0.0 1.1e-20 74.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EWM30275.1 - 3.6e-10 40.2 0.0 0.056 13.3 0.0 4.1 4 0 0 4 4 4 2 AAA domain SMC_N PF02463.14 EWM30275.1 - 1.4e-08 34.2 0.1 0.0019 17.4 0.0 4.1 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 EWM30275.1 - 1.4e-08 34.6 0.0 0.006 16.5 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 EWM30275.1 - 1.6e-07 30.7 0.7 0.021 14.3 0.0 3.1 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 EWM30275.1 - 3.1e-06 26.7 4.0 0.00049 19.5 0.0 3.3 3 0 0 3 3 3 1 AAA domain Miro PF08477.8 EWM30275.1 - 5.4e-06 26.8 0.8 0.081 13.4 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 EWM30275.1 - 1.1e-05 24.6 0.2 0.019 14.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EWM30275.1 - 1.8e-05 24.6 2.7 0.013 15.3 0.1 2.4 2 0 0 2 2 2 2 Dynamin family AAA_23 PF13476.1 EWM30275.1 - 3.7e-05 24.1 0.0 0.046 14.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EWM30275.1 - 5.2e-05 23.3 0.2 0.059 13.3 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EWM30275.1 - 7.1e-05 22.3 0.3 0.81 9.1 0.0 3.3 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_17 PF13207.1 EWM30275.1 - 0.00026 21.7 0.3 0.81 10.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EWM30275.1 - 0.00028 21.0 0.1 0.25 11.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.1 EWM30275.1 - 0.00046 20.0 0.1 0.36 10.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EWM30275.1 - 0.00052 19.0 0.1 0.0091 14.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) FeoB_N PF02421.13 EWM30275.1 - 0.0076 15.5 0.2 5.3 6.3 0.0 2.8 4 0 0 4 4 2 0 Ferrous iron transport protein B PduV-EutP PF10662.4 EWM30275.1 - 0.01 15.3 0.0 3.8 6.9 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EWM30275.1 - 0.013 14.9 0.1 0.14 11.6 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EWM30275.1 - 0.016 14.9 0.6 1.1 8.9 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 EWM30275.1 - 0.019 14.0 0.2 1.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin GTP_EFTU PF00009.22 EWM30275.1 - 0.027 13.8 0.1 0.8 9.1 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_30 PF13604.1 EWM30275.1 - 0.031 13.8 0.4 2 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EWM30275.1 - 0.032 13.9 0.1 0.55 9.8 0.0 2.5 2 0 0 2 2 2 0 NACHT domain T2SE PF00437.15 EWM30275.1 - 0.035 13.0 0.0 1.5 7.6 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_18 PF13238.1 EWM30275.1 - 0.042 14.1 0.0 14 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EWM30275.1 - 0.061 12.7 0.4 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain UPF0079 PF02367.12 EWM30275.1 - 0.072 12.7 0.5 1.6 8.3 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AIG1 PF04548.11 EWM30275.1 - 0.11 11.5 0.2 3.9 6.5 0.0 2.3 2 0 0 2 2 2 0 AIG1 family Septin PF00735.13 EWM30275.1 - 0.18 10.8 0.0 1.9 7.4 0.0 2.1 2 0 0 2 2 2 0 Septin RNA_helicase PF00910.17 EWM30275.1 - 0.27 11.4 0.1 13 6.0 0.0 2.8 3 0 0 3 3 2 0 RNA helicase ATP_bind_1 PF03029.12 EWM30275.1 - 0.28 10.6 0.9 3.5 7.0 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Guanylate_kin PF00625.16 EWM30275.1 - 0.32 10.4 0.2 14 5.0 0.0 2.3 2 0 0 2 2 2 0 Guanylate kinase DUF87 PF01935.12 EWM30275.1 - 0.35 10.6 6.1 1.6 8.4 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_24 PF13479.1 EWM30275.1 - 0.38 10.3 0.1 5.9 6.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.4 EWM30275.1 - 0.42 9.1 0.7 10 4.5 0.0 2.6 3 0 0 3 3 3 0 Predicted ATPase of the ABC class NB-ARC PF00931.17 EWM30275.1 - 0.64 8.8 0.9 15 4.2 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain Spore_IV_A PF09547.5 EWM30275.1 - 1.2 7.7 0.0 1.8 7.1 0.0 1.1 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) MFS_1 PF07690.11 EWM30276.1 - 9.3e-35 119.9 30.3 1.2e-34 119.5 21.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.8 EWM30276.1 - 7.5e-07 27.6 14.5 4.9e-06 24.9 10.0 2.0 1 1 0 1 1 1 1 Transmembrane secretion effector Folate_carrier PF01770.13 EWM30276.1 - 0.00096 17.7 3.1 0.00096 17.7 2.1 1.9 2 0 0 2 2 2 1 Reduced folate carrier OATP PF03137.15 EWM30276.1 - 0.0048 15.0 1.0 0.0048 15.0 0.7 3.0 3 1 1 4 4 4 1 Organic Anion Transporter Polypeptide (OATP) family DUF4392 PF14336.1 EWM30277.1 - 1.1e-76 257.3 0.0 1.3e-76 257.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4392) Acyl_transf_3 PF01757.17 EWM30278.1 - 0.086 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Acyltransferase family Methyltransf_23 PF13489.1 EWM30279.1 - 4.2e-15 55.8 0.0 6.3e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EWM30279.1 - 2.8e-12 46.9 0.0 4.3e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EWM30279.1 - 1.2e-06 28.9 0.0 1.9e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EWM30279.1 - 2.6e-05 23.8 0.0 3.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EWM30279.1 - 7.7e-05 21.9 0.0 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.7 EWM30279.1 - 0.011 15.0 0.0 0.021 14.2 0.0 1.5 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.2 EWM30279.1 - 0.041 14.4 0.0 0.07 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.10 EWM30279.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_29 PF03141.11 EWM30279.1 - 0.19 10.0 0.0 0.26 9.5 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase CS PF04969.11 EWM30280.1 - 6.5e-11 42.6 0.0 9.7e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 CS domain Cytotoxic PF09000.5 EWM30280.1 - 0.11 12.5 0.0 2.9 7.9 0.0 2.5 2 1 0 2 2 2 0 Cytotoxic GTP_EFTU PF00009.22 EWM30281.1 - 6.6e-60 201.7 0.1 1.5e-59 200.5 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EWM30281.1 - 2.7e-35 120.5 0.0 6e-35 119.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EWM30281.1 - 1.2e-19 69.9 0.0 4.7e-19 68.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.1 EWM30281.1 - 1e-14 54.0 0.0 2.4e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EWM30281.1 - 1.6e-11 44.1 0.3 2e-10 40.6 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Dynamin_N PF00350.18 EWM30281.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Dynamin family FAD_binding_4 PF01565.18 EWM30282.1 - 3.3e-08 33.0 0.0 4.8e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain MutH PF02976.10 EWM30282.1 - 0.061 13.2 0.1 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 DNA mismatch repair enzyme MutH ArsA_ATPase PF02374.10 EWM30283.1 - 5.2e-135 449.3 0.0 1.1e-68 231.5 0.0 2.9 2 1 0 2 2 2 2 Anion-transporting ATPase CbiA PF01656.18 EWM30283.1 - 1.2e-26 93.3 3.7 1.1e-11 44.4 0.4 4.3 3 1 0 3 3 3 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EWM30283.1 - 4e-09 36.5 0.0 0.00085 19.2 0.0 3.3 4 0 0 4 4 3 2 AAA domain SRP54 PF00448.17 EWM30283.1 - 3.1e-07 30.0 1.7 0.028 13.8 0.1 3.1 3 0 0 3 3 3 2 SRP54-type protein, GTPase domain Fer4_NifH PF00142.13 EWM30283.1 - 6.9e-07 28.7 1.0 0.0025 17.0 0.0 2.9 3 0 0 3 3 3 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.1 EWM30283.1 - 1.3e-06 27.9 0.5 0.033 13.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EWM30283.1 - 1.6e-06 27.8 0.4 0.012 15.0 0.0 2.7 2 1 0 2 2 2 2 AAA-like domain PhoH PF02562.11 EWM30283.1 - 6.9e-05 22.1 0.8 0.28 10.3 0.1 2.5 2 0 0 2 2 2 2 PhoH-like protein IstB_IS21 PF01695.12 EWM30283.1 - 9.5e-05 21.8 0.4 0.3 10.4 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein ParA PF10609.4 EWM30283.1 - 0.00027 20.7 1.8 0.26 11.1 0.0 3.6 4 0 0 4 4 4 1 ParA/MinD ATPase like MipZ PF09140.6 EWM30283.1 - 0.00056 19.0 0.9 0.29 10.1 0.1 2.5 2 0 0 2 2 2 2 ATPase MipZ ArgK PF03308.11 EWM30283.1 - 0.00073 18.3 1.9 0.31 9.7 0.1 2.5 2 0 0 2 2 2 2 ArgK protein YhjQ PF06564.7 EWM30283.1 - 0.00079 18.8 0.3 0.62 9.3 0.0 2.3 2 0 0 2 2 2 2 YhjQ protein Zeta_toxin PF06414.7 EWM30283.1 - 0.00081 18.5 1.6 0.084 11.9 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin LpxK PF02606.9 EWM30283.1 - 0.0013 17.7 3.1 0.36 9.7 0.3 2.6 2 0 0 2 2 2 2 Tetraacyldisaccharide-1-P 4'-kinase AAA_17 PF13207.1 EWM30283.1 - 0.0016 19.2 0.4 1.6 9.5 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EWM30283.1 - 0.0033 17.4 4.2 1.1 9.2 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_19 PF13245.1 EWM30283.1 - 0.0064 16.2 4.8 1.6 8.4 0.0 4.2 4 0 0 4 4 3 1 Part of AAA domain MobB PF03205.9 EWM30283.1 - 0.01 15.5 1.3 2 8.0 0.0 2.9 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B VirC1 PF07015.6 EWM30283.1 - 0.029 13.4 0.0 2.1 7.3 0.0 2.7 2 0 0 2 2 2 0 VirC1 protein DUF1611 PF07755.6 EWM30283.1 - 0.038 12.6 3.2 0.96 8.0 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1611) DUF815 PF05673.8 EWM30283.1 - 0.067 12.0 0.0 1.4 7.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATP_bind_1 PF03029.12 EWM30283.1 - 0.082 12.4 2.5 4.2 6.8 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 EWM30283.1 - 0.12 12.5 0.2 18 5.5 0.0 2.5 2 0 0 2 2 2 0 RNA helicase APS_kinase PF01583.15 EWM30283.1 - 0.13 11.9 2.8 6.1 6.4 0.0 2.8 3 0 0 3 3 2 0 Adenylylsulphate kinase KTI12 PF08433.5 EWM30283.1 - 0.14 11.3 0.1 15 4.6 0.0 2.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 KaiC PF06745.8 EWM30283.1 - 0.15 11.1 0.4 12 4.9 0.1 2.7 2 0 0 2 2 2 0 KaiC AAA PF00004.24 EWM30283.1 - 0.26 11.4 2.4 20 5.3 0.1 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_26 PF13500.1 EWM30283.1 - 0.49 9.9 5.7 45 3.5 0.1 4.0 4 0 0 4 4 4 0 AAA domain HMG_box PF00505.14 EWM30285.1 - 5.9e-33 112.9 15.0 4.3e-16 58.9 3.1 2.8 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 EWM30285.1 - 6.6e-21 74.4 14.4 7.8e-14 51.7 1.3 2.9 3 0 0 3 3 3 2 HMG-box domain YABBY PF04690.8 EWM30285.1 - 0.017 15.3 3.3 0.017 15.3 2.3 2.6 2 0 0 2 2 2 0 YABBY protein BAF1_ABF1 PF04684.8 EWM30285.1 - 2.7 6.7 12.8 4.5 5.9 8.9 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor FYDLN_acid PF09538.5 EWM30285.1 - 5 7.7 8.4 0.18 12.4 0.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) HMG_box PF00505.14 EWM30286.1 - 5.9e-33 112.9 15.0 4.3e-16 58.9 3.1 2.8 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 EWM30286.1 - 6.6e-21 74.4 14.4 7.8e-14 51.7 1.3 2.9 3 0 0 3 3 3 2 HMG-box domain YABBY PF04690.8 EWM30286.1 - 0.017 15.3 3.3 0.017 15.3 2.3 2.6 2 0 0 2 2 2 0 YABBY protein BAF1_ABF1 PF04684.8 EWM30286.1 - 2.7 6.7 12.8 4.5 5.9 8.9 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor FYDLN_acid PF09538.5 EWM30286.1 - 5 7.7 8.4 0.18 12.4 0.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) p450 PF00067.17 EWM30289.1 - 1.7e-86 290.6 0.0 2.5e-86 290.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PNP_UDP_1 PF01048.15 EWM30290.1 - 1.6e-28 99.3 1.0 2e-28 98.9 0.7 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Oxidored_q6 PF01058.17 EWM30291.1 - 2e-23 82.4 0.1 3.2e-23 81.7 0.1 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit PGI PF00342.14 EWM30292.1 - 1.4e-191 637.2 0.0 1.6e-191 637.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Solute_trans_a PF03619.11 EWM30294.1 - 1.1e-13 51.1 7.0 1.1e-13 51.1 4.9 1.4 2 0 0 2 2 2 1 Organic solute transporter Ostalpha GST_N_3 PF13417.1 EWM30297.1 - 2.8e-20 72.3 0.0 6.9e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EWM30297.1 - 3.4e-16 59.0 0.0 7.8e-16 57.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EWM30297.1 - 1.2e-07 31.5 0.0 4.4e-07 29.6 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EWM30297.1 - 0.00041 20.2 0.0 0.00089 19.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EWM30297.1 - 0.00086 19.7 0.0 0.0025 18.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EWM30297.1 - 0.0035 17.2 0.0 0.0072 16.2 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin HEAT_EZ PF13513.1 EWM30297.1 - 0.34 11.4 3.8 0.68 10.5 0.4 2.7 2 0 0 2 2 2 0 HEAT-like repeat Pkinase PF00069.20 EWM30299.1 - 6.7e-32 110.6 0.0 9.3e-32 110.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM30299.1 - 1.6e-13 50.3 0.0 2.1e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EWM30299.1 - 0.017 14.8 0.2 0.063 12.9 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family DNA_ligase_aden PF01653.13 EWM30300.1 - 3.8e-88 295.4 0.0 1.1e-66 224.9 0.0 3.0 2 1 0 2 2 2 2 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.11 EWM30300.1 - 1.3e-26 92.0 3.7 2.9e-26 90.9 2.6 1.6 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain HHH_2 PF12826.2 EWM30300.1 - 1.4e-08 34.4 0.1 1.9e-05 24.4 0.0 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix motif DNA_ligase_ZBD PF03119.11 EWM30300.1 - 1.2e-07 31.3 5.4 3e-07 30.0 3.8 1.8 1 0 0 1 1 1 1 NAD-dependent DNA ligase C4 zinc finger domain BRCT PF00533.21 EWM30300.1 - 0.00077 19.5 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EWM30300.1 - 0.0024 17.7 0.0 0.0056 16.5 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain Sas10 PF09368.5 EWM30301.1 - 3.9e-24 84.6 11.2 2.4e-23 82.1 5.1 3.0 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EWM30301.1 - 1.7e-17 63.3 0.4 1.7e-17 63.3 0.3 2.8 2 1 0 2 2 2 1 Sas10/Utp3/C1D family TLD PF07534.11 EWM30302.1 - 5e-24 84.8 0.0 1.2e-23 83.6 0.0 1.6 1 0 0 1 1 1 1 TLD RabGAP-TBC PF00566.13 EWM30302.1 - 0.0003 20.3 1.5 0.00046 19.7 1.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CD36 PF01130.16 EWM30303.1 - 5.5e-66 222.7 0.0 1.5e-61 208.1 0.0 2.1 2 0 0 2 2 2 2 CD36 family ATP1G1_PLM_MAT8 PF02038.11 EWM30303.1 - 0.0029 16.5 0.1 0.0064 15.4 0.1 1.5 1 0 0 1 1 1 1 ATP1G1/PLM/MAT8 family UMP1 PF05348.6 EWM30303.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Proteasome maturation factor UMP1 PRA-CH PF01502.13 EWM30304.1 - 9.6e-19 66.7 0.0 1.9e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase DUF1751 PF08551.5 EWM30305.1 - 2.4e-06 27.7 4.9 6.4e-06 26.4 3.4 1.7 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) MRP-S26 PF14943.1 EWM30305.1 - 0.24 10.9 3.9 0.32 10.5 2.7 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Rhomboid PF01694.17 EWM30305.1 - 3.8 7.5 9.8 0.19 11.7 2.7 1.9 2 1 0 2 2 2 0 Rhomboid family DUF1751 PF08551.5 EWM30306.1 - 2e-06 28.0 3.5 2e-06 28.0 2.5 1.6 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 EWM30306.1 - 0.072 13.1 3.3 0.13 12.3 2.3 1.4 1 1 0 1 1 1 0 Rhomboid family MRP-S26 PF14943.1 EWM30306.1 - 0.2 11.2 3.9 0.26 10.8 2.7 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 HSP70 PF00012.15 EWM30307.1 - 3.4e-126 421.5 10.1 5.6e-119 397.7 0.2 3.0 2 1 1 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.8 EWM30307.1 - 9.7e-07 27.6 0.5 1.6e-05 23.6 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein adh_short PF00106.20 EWM30308.1 - 4.8e-17 62.3 0.0 9.1e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EWM30308.1 - 3.8e-07 29.9 0.0 5.8e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EWM30308.1 - 0.0061 16.3 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EWM30308.1 - 0.025 14.0 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RAP PF08373.5 EWM30309.1 - 3.6e-10 39.4 0.0 6.3e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 RAP domain Es2 PF09751.4 EWM30311.1 - 2.4e-46 158.9 0.0 3.9e-34 118.7 0.0 3.2 3 1 0 3 3 3 2 Nuclear protein Es2 CobN-Mg_chel PF02514.11 EWM30311.1 - 0.085 10.2 0.1 0.12 9.7 0.1 1.1 1 0 0 1 1 1 0 CobN/Magnesium Chelatase zf-C3HC4_3 PF13920.1 EWM30312.1 - 0.026 14.1 12.2 0.063 12.9 8.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EWM30312.1 - 0.13 11.8 16.0 0.28 10.8 11.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EWM30312.1 - 2.8 8.0 16.8 6.1 6.9 11.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) IMS PF00817.15 EWM30313.1 - 0.0018 18.0 0.0 0.0074 16.0 0.0 1.9 1 1 0 1 1 1 1 impB/mucB/samB family Complex1_LYR PF05347.10 EWM30314.1 - 5.2e-14 51.7 0.2 5.2e-14 51.7 0.2 1.4 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EWM30314.1 - 6.9e-13 48.5 0.3 1.1e-12 47.9 0.2 1.3 1 0 0 1 1 1 1 Complex1_LYR-like GDE_N_bis PF14742.1 EWM30314.1 - 0.037 13.4 0.0 0.039 13.3 0.0 1.1 1 0 0 1 1 1 0 N-terminal domain of (some) glycogen debranching enzymes DUF547 PF04784.9 EWM30314.1 - 0.12 12.3 0.0 0.21 11.4 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function, DUF547 HSBP1 PF06825.7 EWM30316.1 - 7.3e-18 63.8 0.7 9.9e-18 63.4 0.5 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Hox9_act PF04617.8 EWM30316.1 - 0.018 15.1 0.0 0.021 15.0 0.0 1.2 1 0 0 1 1 1 0 Hox9 activation region EzrA PF06160.7 EWM30316.1 - 0.031 12.4 0.0 0.037 12.2 0.0 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Sipho_Gp157 PF05565.6 EWM30316.1 - 0.1 12.1 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Siphovirus Gp157 FtsK_SpoIIIE PF01580.13 EWM30316.1 - 0.13 11.7 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family Hormone_1 PF00103.15 EWM30316.1 - 0.14 11.4 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Somatotropin hormone family FadA PF09403.5 EWM30316.1 - 0.21 11.5 1.6 5.4 7.0 0.4 2.1 1 1 1 2 2 2 0 Adhesion protein FadA RNA_pol_Rpb4 PF03874.11 EWM30317.1 - 3.4e-09 36.7 0.0 5.6e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 Abhydrolase_6 PF12697.2 EWM30318.1 - 3e-16 60.0 0.0 6.8e-16 58.8 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM30318.1 - 1.8e-08 34.2 0.0 4.2e-08 33.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EWM30318.1 - 2.3e-08 33.8 0.0 4.7e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EWM30318.1 - 0.0032 17.2 0.0 0.0065 16.2 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DUF726 PF05277.7 EWM30318.1 - 0.017 14.0 0.0 0.025 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Lipase_3 PF01764.20 EWM30318.1 - 0.018 14.6 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF900 PF05990.7 EWM30318.1 - 0.048 12.9 0.0 0.093 12.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Methyltransf_15 PF09445.5 EWM30320.1 - 1.8e-39 134.9 0.0 5e-39 133.4 0.0 1.7 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 EWM30320.1 - 4.3e-11 42.8 0.2 1.3e-10 41.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.13 EWM30320.1 - 8e-07 28.7 0.0 1.3e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.2 EWM30320.1 - 1.9e-06 28.4 0.0 3.9e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EWM30320.1 - 3.5e-06 26.7 0.0 5.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.1 EWM30320.1 - 1.4e-05 24.7 0.0 2.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EWM30320.1 - 0.00018 21.8 0.0 0.0004 20.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EWM30320.1 - 0.00025 20.5 0.0 0.00047 19.6 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_3 PF01596.12 EWM30320.1 - 0.00025 20.1 0.0 0.00044 19.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_11 PF08241.7 EWM30320.1 - 0.0027 18.1 0.0 0.0056 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EWM30320.1 - 0.01 15.0 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Birna_VP5 PF03042.9 EWM30320.1 - 0.045 13.2 0.1 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 Birnavirus VP5 protein Porphobil_deam PF01379.15 EWM30321.1 - 1.5e-78 262.6 0.0 1.9e-78 262.3 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EWM30321.1 - 8.7e-19 67.3 0.2 1.5e-18 66.6 0.1 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Tox-GHH PF15636.1 EWM30322.1 - 0.15 11.6 0.2 4.6 6.9 0.0 2.4 1 1 1 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin NAPRTase PF04095.11 EWM30323.1 - 1.9e-29 102.6 0.0 8.5e-28 97.2 0.0 2.1 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family QRPTase_N PF02749.11 EWM30323.1 - 0.0042 16.8 0.0 0.012 15.3 0.0 1.8 2 1 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Med15 PF09606.5 EWM30324.1 - 0.2 9.8 97.0 0.035 12.3 52.0 3.6 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ribophorin_II PF05817.9 EWM30325.1 - 5e-46 157.1 0.0 8e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II UQ_con PF00179.21 EWM30326.1 - 6.3e-34 116.4 0.0 9.6e-34 115.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EWM30326.1 - 0.0019 18.0 0.0 0.0032 17.3 0.0 1.4 1 0 0 1 1 1 1 RWD domain DUF4187 PF13821.1 EWM30327.1 - 2.9e-17 62.0 1.9 6e-17 60.9 1.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 EWM30327.1 - 4.7e-11 42.2 1.6 1.1e-10 41.0 1.1 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EWM30327.1 - 5.3e-05 22.9 1.1 5.3e-05 22.9 0.8 1.8 2 0 0 2 2 2 1 DExH-box splicing factor binding site ATP-synt_ab PF00006.20 EWM30329.1 - 2.2e-107 357.4 0.0 3.6e-107 356.7 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EWM30329.1 - 3.5e-19 69.3 0.4 6.8e-19 68.4 0.3 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EWM30329.1 - 4.9e-14 52.3 0.2 1.5e-13 50.7 0.2 2.0 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_16 PF13191.1 EWM30329.1 - 0.11 12.4 0.0 20 5.1 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain EFP_N PF08207.7 EWM30330.1 - 3.8e-28 97.1 0.1 9.8e-28 95.8 0.1 1.8 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Elong-fact-P_C PF09285.6 EWM30330.1 - 4.1e-22 77.2 1.6 7.3e-22 76.4 0.5 1.9 2 0 0 2 2 2 1 Elongation factor P, C-terminal EFP PF01132.15 EWM30330.1 - 3.7e-16 58.5 1.5 6.7e-16 57.7 1.0 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain GATase_5 PF13507.1 EWM30331.1 - 3.9e-102 340.6 0.0 6.3e-102 339.9 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EWM30331.1 - 5.1e-43 146.7 4.3 4.8e-23 81.8 0.4 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EWM30331.1 - 1.6e-15 57.1 0.4 2.4e-14 53.3 0.0 3.0 2 1 0 2 2 2 1 AIR synthase related protein, N-terminal domain AAA_34 PF13872.1 EWM30332.1 - 5.9e-93 310.9 0.0 8.5e-93 310.4 0.0 1.2 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.1 EWM30332.1 - 6.5e-61 206.1 4.7 2.6e-59 200.9 3.2 2.2 1 1 0 1 1 1 1 Helicase_C-like WD40 PF00400.27 EWM30333.1 - 8.6e-51 168.1 12.2 4.7e-10 38.9 1.1 9.0 9 0 0 9 9 9 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EWM30333.1 - 0.056 12.1 0.1 2.4 6.7 0.0 2.6 2 1 1 3 3 3 0 Nup133 N terminal like ThiF PF00899.16 EWM30334.1 - 3.7e-56 188.7 0.3 1.9e-40 137.8 0.0 2.8 3 0 0 3 3 3 2 ThiF family UBACT PF02134.16 EWM30334.1 - 3.7e-27 93.7 0.1 1.2e-21 76.0 0.0 2.7 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EWM30334.1 - 4e-22 77.3 1.0 7.7e-21 73.2 0.1 2.4 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site UBA_e1_C PF09358.5 EWM30334.1 - 1.6e-21 76.7 0.0 4.6e-21 75.2 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain Shikimate_DH PF01488.15 EWM30334.1 - 1.9e-05 24.7 0.0 0.036 14.1 0.0 2.6 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EWM30334.1 - 5.7e-05 23.3 0.0 0.009 16.2 0.0 2.8 2 0 0 2 2 2 1 Putative NAD(P)-binding Toprim_3 PF13362.1 EWM30334.1 - 0.0033 17.6 0.3 0.021 15.0 0.0 2.4 2 0 0 2 2 2 1 Toprim domain F420_oxidored PF03807.12 EWM30334.1 - 0.0046 17.3 0.4 1.4 9.4 0.0 3.7 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EWM30334.1 - 0.0067 16.0 0.1 0.72 9.4 0.0 2.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EWM30334.1 - 0.0071 16.7 0.2 0.84 10.0 0.0 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EWM30334.1 - 0.012 14.7 0.0 3.2 6.8 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 EWM30334.1 - 0.028 14.4 0.1 7 6.6 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EWM30334.1 - 0.031 14.2 2.2 2.8 7.9 0.0 3.7 4 0 0 4 4 4 0 TrkA-N domain Cupin_3 PF05899.7 EWM30334.1 - 0.062 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) ApbA PF02558.11 EWM30334.1 - 0.11 11.8 0.5 3.1 7.2 0.0 2.7 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Cupin_2 PF07883.6 EWM30334.1 - 0.15 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Cupin domain Aconitase PF00330.15 EWM30335.1 - 4.1e-166 553.0 0.0 8.5e-166 552.0 0.0 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EWM30335.1 - 9.6e-49 164.8 0.0 2.9e-48 163.2 0.0 1.8 2 0 0 2 2 2 1 Aconitase C-terminal domain CTP_transf_1 PF01148.15 EWM30338.1 - 1.1e-51 176.0 18.0 1.4e-51 175.6 12.4 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family DUF2798 PF11391.3 EWM30338.1 - 0.08 12.6 0.3 0.08 12.6 0.2 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2798) Ribosomal_L37ae PF01780.14 EWM30340.1 - 8.4e-38 128.1 8.9 1e-37 127.8 6.2 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family DUF2175 PF09943.4 EWM30340.1 - 0.07 13.1 0.3 12 6.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Zn_Tnp_IS1595 PF12760.2 EWM30340.1 - 0.13 12.0 3.0 0.34 10.7 2.1 1.6 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-Sec23_Sec24 PF04810.10 EWM30340.1 - 0.13 11.8 3.4 0.39 10.3 0.1 2.2 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger A2L_zn_ribbon PF08792.5 EWM30340.1 - 0.15 11.5 4.8 0.35 10.3 0.1 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain OrfB_Zn_ribbon PF07282.6 EWM30340.1 - 0.49 10.0 3.2 0.54 9.9 1.8 1.5 1 1 0 1 1 1 0 Putative transposase DNA-binding domain CarbpepA_inh PF02977.10 EWM30340.1 - 0.57 9.8 4.6 1.2 8.7 1.8 2.3 2 1 0 2 2 2 0 Carboxypeptidase A inhibitor zf-H2C2_2 PF13465.1 EWM30340.1 - 1.1 9.6 4.1 4.7 7.6 0.2 2.7 3 0 0 3 3 3 0 Zinc-finger double domain Malate_synthase PF01274.17 EWM30341.1 - 6.4e-113 377.5 0.0 7.4e-113 377.3 0.0 1.1 1 0 0 1 1 1 1 Malate synthase TRAM_LAG1_CLN8 PF03798.11 EWM30342.1 - 9.2e-28 97.1 14.2 1.2e-27 96.7 9.1 1.6 2 0 0 2 2 2 1 TLC domain Spectrin PF00435.16 EWM30343.1 - 0.013 15.8 2.3 0.065 13.5 1.6 1.9 1 1 0 1 1 1 0 Spectrin repeat SOG2 PF10428.4 EWM30343.1 - 0.031 12.9 0.7 0.036 12.7 0.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein IncA PF04156.9 EWM30343.1 - 0.062 12.8 2.9 0.12 11.9 2.0 1.4 1 0 0 1 1 1 0 IncA protein PAT1 PF09770.4 EWM30343.1 - 0.33 9.1 5.3 0.37 8.9 3.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Troponin-I_N PF11636.3 EWM30343.1 - 5.2 6.8 7.1 17 5.2 1.6 2.4 2 0 0 2 2 2 0 Troponin I residues 1-32 Filamin PF00630.14 EWM30344.1 - 1.3e-09 38.5 0.0 3.6e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 Filamin/ABP280 repeat zf-RING_5 PF14634.1 EWM30344.1 - 8.9e-09 34.9 2.6 8.9e-09 34.9 1.8 3.0 3 0 0 3 3 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EWM30344.1 - 4e-08 32.8 3.2 9.7e-08 31.6 2.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-B_box PF00643.19 EWM30344.1 - 3e-06 26.9 26.9 2.3e-05 24.1 4.8 3.6 3 0 0 3 3 3 2 B-box zinc finger zf-C3HC4 PF00097.20 EWM30344.1 - 5.6e-06 25.9 2.5 5.6e-06 25.9 1.7 2.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EWM30344.1 - 6.6e-06 26.0 4.2 6.6e-06 26.0 2.9 3.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EWM30344.1 - 1.9e-05 24.3 2.5 1.9e-05 24.3 1.8 3.1 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 EWM30344.1 - 0.00037 20.2 4.5 0.00037 20.2 3.1 3.3 4 0 0 4 4 3 1 zinc finger of C3HC4-type, RING NHL PF01436.16 EWM30344.1 - 0.0039 17.0 1.6 26 5.0 0.0 4.3 4 0 0 4 4 4 0 NHL repeat Apolipoprotein PF01442.13 EWM30344.1 - 0.024 14.1 2.8 0.038 13.5 2.0 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Phasin PF05597.6 EWM30344.1 - 0.034 13.9 2.1 0.065 13.0 1.4 1.4 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) PQQ_2 PF13360.1 EWM30344.1 - 0.044 13.2 0.0 1.7 8.0 0.0 2.3 1 1 0 1 1 1 0 PQQ-like domain zf-UDP PF14569.1 EWM30344.1 - 3.4 7.4 9.0 17 5.2 0.4 3.2 3 0 0 3 3 3 0 Zinc-binding RING-finger Prefoldin_2 PF01920.15 EWM30345.1 - 8.8e-20 70.4 1.4 9.2e-20 70.3 0.6 1.3 1 1 0 1 1 1 1 Prefoldin subunit PspA_IM30 PF04012.7 EWM30345.1 - 0.0032 16.8 2.3 0.027 13.8 0.1 2.0 2 0 0 2 2 2 1 PspA/IM30 family ERM PF00769.14 EWM30345.1 - 0.024 14.1 2.2 0.62 9.5 0.1 2.0 2 0 0 2 2 2 0 Ezrin/radixin/moesin family SlyX PF04102.7 EWM30345.1 - 0.027 14.8 4.7 1.1 9.7 0.6 2.4 2 0 0 2 2 2 0 SlyX DASH_Dad3 PF08656.5 EWM30345.1 - 0.034 13.8 1.3 0.049 13.3 0.2 1.7 2 0 0 2 2 2 0 DASH complex subunit Dad3 Spc24 PF08286.6 EWM30345.1 - 0.13 11.9 3.7 0.25 11.0 0.4 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 ATG16 PF08614.6 EWM30345.1 - 0.31 10.8 4.2 0.51 10.1 0.2 2.2 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) FliJ PF02050.11 EWM30345.1 - 0.34 10.9 12.6 1.1e+02 2.8 8.7 2.1 1 1 0 1 1 1 0 Flagellar FliJ protein Tropomyosin_1 PF12718.2 EWM30345.1 - 0.48 10.2 4.7 8.2 6.2 0.4 2.1 2 0 0 2 2 2 0 Tropomyosin like DENN PF02141.16 EWM30346.1 - 1e-42 145.9 5.7 1.7e-42 145.2 4.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 EWM30346.1 - 1.9e-12 47.0 0.5 5.1e-12 45.6 0.3 1.7 1 0 0 1 1 1 1 dDENN domain PPR_3 PF13812.1 EWM30346.1 - 0.00055 20.0 0.5 0.019 15.1 0.1 2.8 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 EWM30346.1 - 0.00097 19.0 0.0 0.021 14.7 0.0 2.5 1 1 1 2 2 2 2 PPR repeat family PPR PF01535.15 EWM30346.1 - 0.014 15.2 0.0 0.27 11.2 0.0 2.6 2 0 0 2 2 2 0 PPR repeat DENN PF02141.16 EWM30347.1 - 1e-42 145.9 5.7 1.7e-42 145.2 4.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 EWM30347.1 - 1.9e-12 47.0 0.5 5.1e-12 45.6 0.3 1.7 1 0 0 1 1 1 1 dDENN domain PPR_3 PF13812.1 EWM30347.1 - 0.00055 20.0 0.5 0.019 15.1 0.1 2.8 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 EWM30347.1 - 0.00097 19.0 0.0 0.021 14.7 0.0 2.5 1 1 1 2 2 2 2 PPR repeat family PPR PF01535.15 EWM30347.1 - 0.014 15.2 0.0 0.27 11.2 0.0 2.6 2 0 0 2 2 2 0 PPR repeat Melibiase PF02065.13 EWM30348.1 - 7.5e-17 61.1 0.1 1.2e-16 60.4 0.1 1.2 1 0 0 1 1 1 1 Melibiase GHL6 PF14871.1 EWM30348.1 - 0.085 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 Raffinose_syn PF05691.7 EWM30348.1 - 0.2 9.1 0.0 0.34 8.4 0.0 1.2 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 MS_channel PF00924.13 EWM30349.1 - 1.4e-34 119.2 0.0 1.9e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel DUF605 PF04652.11 EWM30349.1 - 9.4 5.5 11.1 15 4.8 7.7 1.2 1 0 0 1 1 1 0 Vta1 like DEAD PF00270.24 EWM30350.1 - 2e-37 128.2 0.0 3.3e-37 127.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EWM30350.1 - 6.1e-20 70.8 0.0 1.4e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EWM30350.1 - 1.6e-15 56.3 0.2 5.1e-15 54.7 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EWM30350.1 - 4.9e-05 23.2 0.0 0.00015 21.6 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EWM30350.1 - 0.00021 20.1 0.0 0.00034 19.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 EWM30350.1 - 0.036 14.1 0.0 0.15 12.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain Cyclin_N PF00134.18 EWM30351.1 - 3.1e-07 30.0 0.0 5.1e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain GPP34 PF05719.6 EWM30351.1 - 0.091 12.8 0.3 0.23 11.5 0.2 1.7 1 1 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) Rad60-SLD_2 PF13881.1 EWM30352.1 - 3.9e-08 33.1 0.0 0.00026 20.8 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EWM30352.1 - 0.031 14.4 0.0 3.5 7.8 0.0 2.2 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain zf-AN1 PF01428.11 EWM30353.1 - 1.8e-11 43.6 8.9 1.8e-11 43.6 6.1 2.1 2 0 0 2 2 2 1 AN1-like Zinc finger zf-A20 PF01754.11 EWM30353.1 - 1.8e-07 30.5 7.1 3.9e-07 29.5 4.9 1.6 1 0 0 1 1 1 1 A20-like zinc finger DUF4428 PF14471.1 EWM30353.1 - 0.005 16.5 5.1 0.19 11.4 0.2 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4428) zf-AN1 PF01428.11 EWM30354.1 - 1.8e-11 43.6 8.9 1.8e-11 43.6 6.1 2.1 2 0 0 2 2 2 1 AN1-like Zinc finger zf-A20 PF01754.11 EWM30354.1 - 1.8e-07 30.5 7.1 3.9e-07 29.5 4.9 1.6 1 0 0 1 1 1 1 A20-like zinc finger DUF4428 PF14471.1 EWM30354.1 - 0.005 16.5 5.1 0.19 11.4 0.2 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4428) PA28_beta PF02252.13 EWM30356.1 - 1.8e-40 137.8 0.0 2.7e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit DUF276 PF03434.8 EWM30356.1 - 0.042 12.8 0.1 0.061 12.2 0.0 1.2 1 0 0 1 1 1 0 DUF276 PA28_alpha PF02251.13 EWM30356.1 - 0.098 12.8 0.4 0.29 11.3 0.1 1.9 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit Sec20 PF03908.8 EWM30357.1 - 1.8e-06 27.5 0.1 5.5e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 Sec20 V-SNARE PF05008.10 EWM30357.1 - 0.00077 19.5 2.0 0.00077 19.5 1.4 2.3 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus SNARE PF05739.14 EWM30357.1 - 0.0035 16.9 1.9 0.42 10.3 0.2 2.6 2 0 0 2 2 2 1 SNARE domain V-SNARE_C PF12352.3 EWM30357.1 - 0.0037 17.2 0.4 0.011 15.8 0.3 1.8 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus MerR-DNA-bind PF09278.6 EWM30357.1 - 0.0038 17.5 0.2 13 6.3 0.0 3.3 3 0 0 3 3 3 0 MerR, DNA binding DUF4407 PF14362.1 EWM30357.1 - 0.0045 15.9 4.4 0.0068 15.3 3.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) NPV_P10 PF05531.7 EWM30357.1 - 0.006 16.8 0.7 1.5 9.1 0.4 3.1 3 0 0 3 3 3 1 Nucleopolyhedrovirus P10 protein MtrB PF05440.7 EWM30357.1 - 0.015 15.3 0.1 0.049 13.6 0.0 1.9 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B L31 PF09784.4 EWM30357.1 - 0.19 11.8 2.0 0.33 11.0 0.2 2.2 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L31 Tektin PF03148.9 EWM30357.1 - 0.33 9.4 7.0 1.5 7.2 0.0 2.9 2 1 0 3 3 3 0 Tektin family TMF_DNA_bd PF12329.3 EWM30357.1 - 0.42 10.4 13.6 2.2 8.1 0.5 3.7 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding Sugarporin_N PF11471.3 EWM30357.1 - 0.49 10.0 3.4 0.23 11.1 0.3 1.9 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension DUF4140 PF13600.1 EWM30357.1 - 1 9.8 7.1 4.8 7.6 0.5 3.0 2 2 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) CCDC-167 PF15188.1 EWM30357.1 - 2 8.4 4.7 7.3 6.6 0.5 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 ERM PF00769.14 EWM30357.1 - 2 7.8 11.1 0.16 11.5 0.7 2.5 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Mnd1 PF03962.10 EWM30357.1 - 4.6 6.8 11.7 57 3.3 8.1 2.2 1 1 0 1 1 1 0 Mnd1 family zf-C4H2 PF10146.4 EWM30357.1 - 5.3 7.0 6.3 1.5 8.8 0.8 2.0 1 1 1 2 2 2 0 Zinc finger-containing protein Glycos_transf_2 PF00535.21 EWM30358.1 - 7.1e-31 107.1 0.0 9.6e-31 106.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EWM30358.1 - 7.3e-12 45.5 0.0 1e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EWM30358.1 - 6.5e-07 28.8 0.0 1.2e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.4 EWM30358.1 - 0.0079 15.3 0.0 0.0098 15.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Syja_N PF02383.13 EWM30359.1 - 7e-77 258.3 0.0 1.3e-76 257.3 0.0 1.4 2 0 0 2 2 2 1 SacI homology domain SPT16 PF08644.6 EWM30360.1 - 4.4e-47 159.7 0.2 1.1e-46 158.4 0.1 1.7 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.19 EWM30360.1 - 8.5e-25 87.5 0.0 1.5e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 FACT-Spt16_Nlob PF14826.1 EWM30360.1 - 2.6e-22 79.0 0.0 8.4e-22 77.4 0.0 2.0 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Rtt106 PF08512.7 EWM30360.1 - 6.2e-16 58.1 0.3 1.6e-15 56.8 0.2 1.7 1 0 0 1 1 1 1 Histone chaperone Rttp106-like CK_II_beta PF01214.13 EWM30361.1 - 7.3e-65 217.9 2.0 2.6e-55 186.7 0.9 2.1 1 1 0 2 2 2 2 Casein kinase II regulatory subunit DUF1162 PF06650.7 EWM30363.1 - 2.9e-15 56.2 0.0 1.1e-06 28.0 0.0 3.7 3 1 1 4 4 4 4 Protein of unknown function (DUF1162) EF-hand_7 PF13499.1 EWM30363.1 - 6.5e-05 22.9 0.0 0.0002 21.4 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair ATG_C PF09333.6 EWM30363.1 - 9e-05 22.5 0.0 0.00026 21.0 0.0 1.7 1 0 0 1 1 1 1 ATG C terminal domain EF-hand_1 PF00036.27 EWM30363.1 - 0.00018 20.5 0.0 0.00056 19.0 0.0 1.9 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 EWM30363.1 - 0.00043 19.5 0.3 0.0071 15.6 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EWM30363.1 - 0.0012 18.5 0.0 0.0042 16.8 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.1 EWM30363.1 - 0.081 12.5 0.0 0.24 11.0 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair Nup96 PF12110.3 EWM30364.1 - 6.6e-38 130.4 0.0 1.3e-37 129.5 0.0 1.5 1 1 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 EWM30364.1 - 3.1e-27 95.1 0.0 4.3e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin autopeptidase WD40 PF00400.27 EWM30365.1 - 4.5e-56 184.8 13.4 4.1e-11 42.3 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EWM30365.1 - 8.3e-05 20.9 5.9 0.21 9.6 0.0 4.1 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EWM30365.1 - 0.0019 17.0 0.1 5.8 5.5 0.0 4.1 1 1 3 4 4 4 2 Nup133 N terminal like RCC1_2 PF13540.1 EWM30365.1 - 0.1 12.2 3.4 0.54 9.9 0.2 2.9 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat RabGAP-TBC PF00566.13 EWM30367.1 - 1e-14 54.5 0.0 1.4e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain eIF3_subunit PF08597.5 EWM30368.1 - 1.4e-13 50.9 9.6 1.7e-13 50.6 6.6 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit CT47 PF15623.1 EWM30368.1 - 0.53 9.9 15.1 0.78 9.4 10.5 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 Nop14 PF04147.7 EWM30368.1 - 1.6 6.5 12.9 2.1 6.1 8.9 1.1 1 0 0 1 1 1 0 Nop14-like family CCDC66 PF15236.1 EWM30368.1 - 2.1 7.9 21.7 3.1 7.4 15.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 BTV_NS2 PF04514.7 EWM30368.1 - 2.3 7.0 6.3 3.6 6.3 4.3 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF4407 PF14362.1 EWM30368.1 - 7.4 5.4 8.6 9.9 5.0 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FimP PF09766.4 EWM30369.1 - 4.6e-18 65.4 0.0 2.1e-17 63.2 0.0 1.9 2 0 0 2 2 2 1 Fms-interacting protein DivIC PF04977.10 EWM30369.1 - 0.37 10.3 2.0 8 6.0 0.0 2.6 2 0 0 2 2 2 0 Septum formation initiator Peptidase_M16_C PF05193.16 EWM30370.1 - 3.4e-37 127.9 0.0 6.8e-37 126.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EWM30370.1 - 5.1e-34 117.1 0.1 1.2e-33 116.0 0.0 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) RCC1 PF00415.13 EWM30371.1 - 2.8e-74 245.1 26.7 2e-17 63.1 0.0 8.3 7 1 1 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EWM30371.1 - 8.2e-44 146.3 30.7 5.5e-09 35.4 0.7 8.3 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 EWM30371.1 - 0.0013 18.1 0.0 9.2 5.8 0.0 3.4 3 0 0 3 3 3 2 Putative carbohydrate binding domain Uricase PF01014.13 EWM30372.1 - 6.1e-53 178.6 0.0 2.2e-29 102.2 0.4 2.0 2 0 0 2 2 2 2 Uricase Proteasome PF00227.21 EWM30373.1 - 1.6e-17 63.4 0.0 3.1e-17 62.5 0.0 1.5 1 1 0 1 1 1 1 Proteasome subunit ACOX PF01756.14 EWM30374.1 - 6.2e-33 113.7 0.0 1.1e-27 96.5 0.0 2.2 2 0 0 2 2 2 2 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EWM30374.1 - 6.3e-29 100.8 0.0 1e-28 100.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EWM30374.1 - 1.8e-09 36.9 0.0 3.9e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EWM30374.1 - 3.7e-05 23.8 0.2 0.0013 18.8 0.0 2.8 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain GlnD_UR_UTase PF08335.6 EWM30374.1 - 0.039 13.7 0.3 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 GlnD PII-uridylyltransferase DnaJ PF00226.26 EWM30375.1 - 6e-26 89.9 4.1 1.1e-25 89.1 2.8 1.4 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.15 EWM30375.1 - 4.8e-18 64.7 0.0 2.1e-13 49.8 0.1 2.5 2 0 0 2 2 2 2 Thioredoxin Armet PF10208.4 EWM30375.1 - 3.2e-07 30.1 1.6 4.2e-07 29.7 0.1 1.9 2 0 0 2 2 2 1 Degradation arginine-rich protein for mis-folding Thioredoxin_3 PF13192.1 EWM30375.1 - 0.0063 16.3 0.1 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_4 PF13462.1 EWM30375.1 - 0.02 14.8 0.6 0.25 11.3 0.1 2.6 2 1 1 3 3 3 0 Thioredoxin AhpC-TSA PF00578.16 EWM30375.1 - 0.11 12.1 0.0 0.34 10.6 0.0 1.8 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_8 PF13905.1 EWM30375.1 - 0.13 12.3 0.0 0.76 9.9 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin-like Nfu_N PF08712.6 EWM30376.1 - 2.9e-25 87.6 0.0 7.6e-25 86.3 0.0 1.7 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 EWM30376.1 - 1.3e-19 69.7 0.0 2.4e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain Pkinase PF00069.20 EWM30377.1 - 7.4e-65 218.6 0.0 1.2e-64 218.0 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM30377.1 - 1.7e-33 115.7 0.0 5.1e-32 110.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EWM30377.1 - 0.039 13.6 0.0 0.085 12.5 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family eIF-6 PF01912.13 EWM30379.1 - 1.6e-82 275.4 0.4 2.3e-82 274.9 0.3 1.2 1 0 0 1 1 1 1 eIF-6 family Peptidase_C48 PF02902.14 EWM30380.1 - 1e-11 44.8 0.0 2.8e-11 43.4 0.0 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Pkinase PF00069.20 EWM30382.1 - 3.5e-59 200.0 0.0 4.2e-59 199.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM30382.1 - 6.2e-32 110.6 0.0 8.5e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EWM30382.1 - 1.2e-05 25.1 2.0 0.001 18.8 0.1 2.6 2 1 0 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 EWM30382.1 - 0.0011 18.1 0.3 0.0011 18.1 0.2 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EWM30382.1 - 0.013 14.4 0.1 1.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.17 EWM30382.1 - 0.047 13.0 0.0 0.085 12.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Aldo_ket_red PF00248.16 EWM30383.1 - 2.6e-74 249.5 0.0 3.4e-74 249.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF4336 PF14234.1 EWM30385.1 - 4.7e-79 265.5 3.2 1.7e-55 188.2 0.1 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4336) Glucosamine_iso PF01182.15 EWM30386.1 - 4.1e-09 36.4 0.0 4.2e-07 29.8 0.0 2.6 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase PIG-L PF02585.12 EWM30386.1 - 1.7e-06 28.5 0.0 5.3e-05 23.7 0.0 3.1 2 1 0 2 2 2 1 GlcNAc-PI de-N-acetylase Ribosomal_L24e PF01246.15 EWM30387.1 - 9.6e-23 79.8 0.8 9.6e-23 79.8 0.5 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e DUF2521 PF10730.4 EWM30387.1 - 0.14 11.9 3.0 2.4 7.9 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2521) DUF4551 PF15087.1 EWM30387.1 - 0.78 8.0 4.0 0.86 7.8 2.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF2098 PF09871.4 EWM30387.1 - 5.1 7.1 6.3 1.4 8.8 1.7 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) MRP-L27 PF09809.4 EWM30388.1 - 4.1e-13 48.9 0.3 5.2e-13 48.5 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Ras PF00071.17 EWM30389.1 - 1.6e-58 196.6 0.1 2.1e-58 196.2 0.1 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EWM30389.1 - 6.2e-19 68.6 0.1 9.5e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EWM30389.1 - 5.4e-16 58.3 0.1 8.3e-16 57.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EWM30389.1 - 1.7e-07 30.6 0.0 2.2e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EWM30389.1 - 9.8e-06 25.5 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EWM30389.1 - 0.00033 20.1 0.0 0.00066 19.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EWM30389.1 - 0.00091 18.4 0.0 0.0015 17.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 EWM30389.1 - 0.0049 16.8 0.0 0.084 12.8 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.8 EWM30389.1 - 0.049 12.5 0.0 0.17 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_15 PF13175.1 EWM30389.1 - 0.078 12.0 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.15 EWM30389.1 - 0.089 11.4 0.1 1.2 7.7 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit Septin PF00735.13 EWM30389.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_22 PF13401.1 EWM30389.1 - 0.13 12.4 0.0 0.34 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EWM30389.1 - 0.16 11.1 0.0 0.52 9.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ABC2_membrane PF01061.19 EWM30390.1 - 1.7e-40 138.4 12.0 1.7e-40 138.4 8.3 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 EWM30390.1 - 3.1e-24 85.8 0.0 2.8e-23 82.7 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.1 EWM30390.1 - 4.9e-08 33.1 0.0 8.3e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 EWM30390.1 - 1.5e-07 31.7 0.4 0.024 14.6 0.0 2.3 1 1 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 EWM30390.1 - 7e-07 28.5 16.8 1.5e-06 27.5 11.3 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_25 PF13481.1 EWM30390.1 - 4.6e-05 22.9 0.2 0.00095 18.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 EWM30390.1 - 5e-05 22.6 0.1 0.00051 19.3 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EWM30390.1 - 0.00079 19.5 0.1 0.011 15.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EWM30390.1 - 0.00093 18.9 0.3 0.028 14.1 0.0 3.1 3 0 0 3 3 3 1 Part of AAA domain AAA_29 PF13555.1 EWM30390.1 - 0.0012 18.3 0.1 0.004 16.6 0.0 1.9 2 0 0 2 2 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EWM30390.1 - 0.0013 17.9 0.0 0.0024 17.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EWM30390.1 - 0.0014 19.3 0.0 0.0028 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 EWM30390.1 - 0.0037 16.7 0.0 0.0066 15.9 0.0 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 EWM30390.1 - 0.0039 17.5 0.1 0.0079 16.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EWM30390.1 - 0.0054 16.9 0.1 0.084 13.0 0.0 2.6 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EWM30390.1 - 0.021 15.1 0.0 0.041 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EWM30390.1 - 0.034 14.1 0.0 0.078 12.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Arch_ATPase PF01637.13 EWM30390.1 - 0.037 13.7 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase SbcCD_C PF13558.1 EWM30390.1 - 0.04 13.8 1.3 0.25 11.2 0.0 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.13 EWM30390.1 - 0.047 13.1 0.0 0.099 12.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_28 PF13521.1 EWM30390.1 - 0.057 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EWM30390.1 - 0.086 12.2 0.1 0.18 11.1 0.1 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_14 PF13173.1 EWM30390.1 - 0.098 12.5 0.0 0.37 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EWM30390.1 - 0.099 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EWM30390.1 - 0.1 12.1 0.2 0.24 10.8 0.0 1.7 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 EWM30390.1 - 0.11 12.2 0.0 0.28 10.8 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 EWM30390.1 - 0.12 11.3 0.0 0.38 9.6 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Fe-S_biosyn PF01521.15 EWM30391.1 - 7.9e-13 48.3 0.0 1.2e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis tRNA-synt_2 PF00152.15 EWM30392.1 - 1.9e-71 240.6 0.1 3.5e-71 239.7 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EWM30392.1 - 2e-12 46.7 0.6 6.1e-12 45.2 0.3 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EWM30392.1 - 0.034 13.3 0.4 2.5 7.2 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) DUF1767 PF08585.7 EWM30393.1 - 9e-06 25.8 0.1 1.4e-05 25.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) CPSF_A PF03178.10 EWM30394.1 - 3.5e-84 282.6 0.0 3.7e-82 275.9 0.0 2.4 2 0 0 2 2 2 2 CPSF A subunit region MMS1_N PF10433.4 EWM30394.1 - 9.5e-63 212.0 0.0 1.3e-62 211.5 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term WD40 PF00400.27 EWM30394.1 - 0.4 10.6 2.1 0.84 9.6 0.0 2.7 3 0 0 3 3 3 0 WD domain, G-beta repeat PIP5K PF01504.13 EWM30396.1 - 2.4e-49 167.7 0.0 3.9e-49 167.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase TetR_C PF02909.12 EWM30396.1 - 0.1 12.2 0.4 0.22 11.1 0.3 1.5 1 0 0 1 1 1 0 Tetracyclin repressor, C-terminal all-alpha domain BAF1_ABF1 PF04684.8 EWM30396.1 - 3.5 6.3 20.2 4.7 5.9 14.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor F-box-like PF12937.2 EWM30397.1 - 1.1e-05 25.0 0.5 2.1e-05 24.1 0.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EWM30397.1 - 0.014 15.0 0.1 0.034 13.8 0.1 1.6 1 0 0 1 1 1 0 F-box domain DUF2413 PF10310.4 EWM30397.1 - 0.054 12.2 0.4 0.076 11.8 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Macoilin PF09726.4 EWM30397.1 - 0.12 10.6 2.0 0.17 10.1 1.4 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF4106 PF13388.1 EWM30397.1 - 0.58 9.0 4.7 0.81 8.5 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) PAT1 PF09770.4 EWM30397.1 - 0.75 7.9 8.8 0.97 7.5 6.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 EWM30397.1 - 5.9 6.1 10.6 9.1 5.5 7.4 1.2 1 0 0 1 1 1 0 Vta1 like AIM24 PF01987.12 EWM30398.1 - 3.1e-16 59.4 0.1 4e-16 59.1 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF1445 PF07286.7 EWM30399.1 - 6.3e-65 217.1 0.0 8.3e-65 216.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) DBR1 PF05011.8 EWM30400.1 - 3.6e-27 95.0 0.0 7.3e-27 94.0 0.0 1.5 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 EWM30400.1 - 8.2e-11 41.6 0.1 5.1e-10 39.0 0.1 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EWM30400.1 - 0.0017 18.2 0.0 0.0037 17.1 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PIG-U PF06728.8 EWM30401.1 - 1e-30 106.8 21.2 1.4e-30 106.4 14.7 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U DUF2046 PF09755.4 EWM30403.1 - 1.8e-26 92.7 41.9 8.9e-20 70.7 13.5 2.5 1 1 1 2 2 2 2 Uncharacterized conserved protein H4 (DUF2046) PLRV_ORF5 PF01690.12 EWM30403.1 - 0.062 12.4 8.9 0.079 12.0 6.2 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein CAML PF14963.1 EWM30403.1 - 0.26 10.6 0.1 0.26 10.6 0.1 2.1 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand Baculo_PEP_C PF04513.7 EWM30403.1 - 1.4 8.7 11.8 6.7 6.5 6.2 2.7 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Atg14 PF10186.4 EWM30403.1 - 5.4 5.8 25.6 9.3 5.0 17.7 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Pap_E4 PF02711.9 EWM30405.1 - 0.3 11.9 2.6 0.44 11.3 1.8 1.4 1 0 0 1 1 1 0 E4 protein UAA PF08449.6 EWM30406.1 - 1e-65 221.6 18.6 1.3e-65 221.3 12.9 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EWM30406.1 - 0.0018 17.9 10.0 0.0018 17.9 7.0 2.3 3 0 0 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 EWM30406.1 - 0.0063 16.5 21.3 0.0079 16.2 4.5 3.1 2 1 1 3 3 3 2 EamA-like transporter family HIG_1_N PF04588.8 EWM30408.1 - 1.2e-18 66.5 3.9 9.3e-09 34.9 1.8 2.2 2 0 0 2 2 2 2 Hypoxia induced protein conserved region P5CR_dimer PF14748.1 EWM30409.1 - 1.3e-33 115.1 0.1 2.3e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EWM30409.1 - 4.8e-15 55.7 0.0 9.6e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EWM30409.1 - 1.5e-05 24.8 0.0 2.6e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 EWM30409.1 - 7.3e-05 22.5 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GFO_IDH_MocA PF01408.17 EWM30409.1 - 0.00046 20.6 0.0 0.00095 19.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ApbA PF02558.11 EWM30409.1 - 0.0024 17.2 0.0 0.0044 16.4 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EWM30409.1 - 0.0025 17.5 0.3 0.014 15.0 0.2 2.0 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EWM30409.1 - 0.0033 17.5 0.0 0.006 16.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_C PF03720.10 EWM30409.1 - 0.0035 17.4 0.0 0.0084 16.2 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 2-Hacid_dh_C PF02826.14 EWM30409.1 - 0.015 14.4 0.0 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EWM30409.1 - 0.071 13.3 0.0 0.31 11.3 0.0 2.0 1 1 1 2 2 2 0 Putative NAD(P)-binding Sulfotransfer_1 PF00685.22 EWM30410.1 - 2e-28 99.4 0.0 3e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 EWM30410.1 - 1.6e-05 25.8 1.3 8.3e-05 23.5 0.1 2.4 2 1 0 2 2 2 1 Sulfotransferase family DnaJ PF00226.26 EWM30411.1 - 4.5e-21 74.3 0.0 7.1e-21 73.7 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Sugar_transport PF06800.7 EWM30412.1 - 3.8e-06 26.1 0.8 6.3e-06 25.4 0.5 1.3 1 0 0 1 1 1 1 Sugar transport protein DUF1632 PF07857.7 EWM30412.1 - 0.041 13.1 5.2 0.089 12.0 0.1 2.1 2 0 0 2 2 2 0 CEO family (DUF1632) Sdh_cyt PF01127.17 EWM30412.1 - 0.26 11.1 5.2 0.2 11.4 1.4 2.1 1 1 1 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Abi PF02517.11 EWM30412.1 - 1.7 8.8 5.3 5.4 7.2 3.7 2.0 1 1 0 1 1 1 0 CAAX protease self-immunity 7TM-7TMR_HD PF07698.6 EWM30412.1 - 2.4 7.5 11.1 6.2 6.2 7.7 1.6 1 1 0 1 1 1 0 7TM receptor with intracellular HD hydrolase TPR_2 PF07719.12 EWM30413.1 - 6.7e-08 31.8 3.1 0.0057 16.4 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EWM30413.1 - 3.8e-07 29.6 2.0 1.4e-05 24.5 0.0 3.0 2 1 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EWM30413.1 - 0.037 13.6 0.3 11 5.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EWM30413.1 - 0.14 12.8 12.2 1.2 9.8 0.6 3.6 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EWM30413.1 - 3.8 8.4 7.2 72 4.4 1.1 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.20 EWM30414.1 - 1.4e-37 129.3 0.1 2.8e-18 66.0 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EWM30414.1 - 2.2e-12 46.6 0.2 3.2e-07 29.6 0.1 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase Imm19 PF15567.1 EWM30414.1 - 0.022 14.7 0.0 0.066 13.2 0.0 1.7 1 0 0 1 1 1 0 Immunity protein 19 COPI_assoc PF08507.5 EWM30415.1 - 1.2e-10 41.1 2.6 1.8e-10 40.6 1.8 1.1 1 0 0 1 1 1 1 COPI associated protein DUF2244 PF10003.4 EWM30415.1 - 0.0022 17.3 5.0 0.089 12.1 3.5 2.2 2 0 0 2 2 2 1 Integral membrane protein (DUF2244) DC_STAMP PF07782.8 EWM30415.1 - 0.11 12.1 1.8 0.11 12.0 0.4 1.6 1 1 1 2 2 2 0 DC-STAMP-like protein DUF4383 PF14325.1 EWM30415.1 - 0.73 9.8 7.3 1 9.4 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4383) Bax1-I PF01027.15 EWM30415.1 - 1 8.8 11.6 1.4 8.4 8.0 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 MARVEL PF01284.18 EWM30415.1 - 2.8 7.7 14.5 1.1e+03 -0.7 10.1 2.3 1 1 0 1 1 1 0 Membrane-associating domain SNARE PF05739.14 EWM30416.1 - 9.7e-06 25.1 3.9 9.7e-06 25.1 2.7 3.1 3 0 0 3 3 3 1 SNARE domain Syntaxin-6_N PF09177.6 EWM30416.1 - 0.00017 21.9 4.3 0.00017 21.9 3.0 3.0 3 1 0 3 3 3 1 Syntaxin 6, N-terminal Lipoprotein_6 PF01441.14 EWM30416.1 - 0.05 13.4 7.9 0.053 13.3 1.5 2.4 2 0 0 2 2 2 0 Lipoprotein DegS PF05384.6 EWM30416.1 - 0.25 10.5 12.4 0.014 14.5 3.6 2.3 2 0 0 2 2 2 0 Sensor protein DegS DUF1664 PF07889.7 EWM30416.1 - 4.5 7.0 16.4 8.7 6.1 1.9 4.0 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) AAA_13 PF13166.1 EWM30416.1 - 4.9 5.4 11.4 3.1 6.1 1.6 2.1 2 0 0 2 2 2 0 AAA domain DUF1104 PF06518.6 EWM30416.1 - 7.1 6.8 13.2 0.37 10.9 4.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1104) COG5 PF10392.4 EWM30416.1 - 7.9 6.4 8.8 2.6 8.0 1.3 2.7 3 0 0 3 3 3 0 Golgi transport complex subunit 5 14-3-3 PF00244.15 EWM30417.1 - 4.1e-110 366.4 1.6 4.8e-110 366.2 1.1 1.0 1 0 0 1 1 1 1 14-3-3 protein Rhomboid PF01694.17 EWM30418.1 - 3.1e-10 40.2 8.7 3.1e-10 40.2 6.1 2.4 2 1 0 2 2 2 1 Rhomboid family PX PF00787.19 EWM30419.1 - 3.6e-17 62.1 0.0 7.4e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 PX domain Tim17 PF02466.14 EWM30420.1 - 7.3e-14 51.9 7.2 1.2e-13 51.2 5.0 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Romo1 PF10247.4 EWM30420.1 - 0.34 11.1 2.9 0.34 11.1 0.4 2.0 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 TIM21 PF08294.6 EWM30421.1 - 5.1e-15 55.3 0.0 7.9e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 TIM21 Antimicrobial_8 PF08103.6 EWM30422.1 - 5.3 7.1 5.7 1.1 9.3 1.3 2.0 2 0 0 2 2 2 0 Uperin family Glycos_transf_1 PF00534.15 EWM30423.1 - 7.8e-25 87.2 0.0 1.3e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EWM30423.1 - 1.1e-10 41.7 0.0 2.3e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 NADH-G_4Fe-4S_3 PF10588.4 EWM30424.1 - 1.5e-17 62.5 0.2 7.7e-17 60.2 0.1 2.2 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.1 EWM30424.1 - 1.3e-15 56.9 0.0 2.3e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.22 EWM30424.1 - 3.9e-09 36.1 0.9 1.4e-08 34.3 0.0 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.22 EWM30424.1 - 0.022 14.3 1.4 1.5 8.5 0.3 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_15 PF13459.1 EWM30424.1 - 0.025 15.1 0.1 0.063 13.8 0.1 1.6 1 0 0 1 1 1 0 4Fe-4S single cluster domain Fer4_19 PF06902.6 EWM30424.1 - 0.09 12.6 1.8 1.4 8.7 1.3 2.6 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Ten1_2 PF15490.1 EWM30426.1 - 1e-27 96.0 0.7 1.2e-27 95.8 0.5 1.1 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit Rep_fac-A_3 PF08661.6 EWM30426.1 - 4.7e-06 26.4 0.0 1e-05 25.3 0.0 1.5 1 1 0 1 1 1 1 Replication factor A protein 3 Actin PF00022.14 EWM30427.1 - 8.3e-88 294.4 0.0 1.1e-87 294.1 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EWM30427.1 - 0.15 10.6 0.0 0.25 9.8 0.0 1.4 1 0 0 1 1 1 0 MreB/Mbl protein 2OG-FeII_Oxy_2 PF13532.1 EWM30428.1 - 3.8e-09 36.6 0.0 7.5e-09 35.6 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EWM30428.1 - 0.025 14.8 0.0 0.068 13.4 0.0 1.9 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Glyco_hydro_18 PF00704.23 EWM30429.1 - 0.00014 21.4 0.0 0.00022 20.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 UPF0233 PF06781.7 EWM30429.1 - 0.068 12.7 1.1 0.13 11.8 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) Arm PF00514.18 EWM30430.1 - 2.5e-50 166.6 29.1 1.3e-10 40.7 0.1 8.3 7 1 1 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EWM30430.1 - 6.4e-19 67.8 15.8 1.3e-07 31.8 0.2 6.3 5 1 1 6 6 6 5 HEAT-like repeat HEAT_2 PF13646.1 EWM30430.1 - 1.1e-18 67.2 9.2 1.2e-07 31.9 0.1 5.6 1 1 6 7 7 7 7 HEAT repeats IBB PF01749.15 EWM30430.1 - 4.3e-13 49.2 3.2 9.4e-13 48.1 2.3 1.6 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 EWM30430.1 - 4.8e-07 29.3 14.1 0.00036 20.3 0.0 7.3 8 2 0 8 8 8 1 HEAT repeat HEAT_PBS PF03130.11 EWM30430.1 - 0.0038 17.5 6.8 10 6.9 0.0 6.2 6 1 0 6 6 6 1 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.4 EWM30430.1 - 0.054 13.2 0.0 3.7 7.3 0.0 2.9 2 1 1 3 3 3 0 Spinocerebellar ataxia type 10 protein domain V-ATPase_H_N PF03224.9 EWM30430.1 - 0.085 11.9 0.0 1 8.3 0.0 2.4 3 0 0 3 3 3 0 V-ATPase subunit H WD40 PF00400.27 EWM30431.1 - 2e-19 68.6 6.5 6.6e-11 41.6 0.1 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat DPPIV_N PF00930.16 EWM30431.1 - 0.022 13.3 0.4 0.11 11.1 0.1 1.9 1 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Abhydrolase_5 PF12695.2 EWM30432.1 - 2.3e-23 82.5 0.1 3.7e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EWM30432.1 - 1.2e-19 71.1 2.1 1.8e-17 63.9 0.4 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EWM30432.1 - 7.6e-11 42.0 0.0 1.1e-07 31.6 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.7 EWM30432.1 - 6.8e-08 31.3 0.2 0.012 14.0 0.0 3.0 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.8 EWM30432.1 - 9.1e-07 28.6 0.1 1.7e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EWM30432.1 - 1.1e-06 27.9 0.0 0.0073 15.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.15 EWM30432.1 - 2.1e-05 24.0 0.0 5.5e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.13 EWM30432.1 - 0.00014 21.3 0.0 0.0013 18.2 0.0 2.4 3 0 0 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) DUF818 PF05677.7 EWM30432.1 - 0.00024 19.9 0.0 0.00033 19.4 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) BAAT_C PF08840.6 EWM30432.1 - 0.0008 19.1 0.0 0.0053 16.4 0.0 2.0 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 EWM30432.1 - 0.0014 17.9 0.0 0.34 10.1 0.0 2.6 3 0 0 3 3 3 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EWM30432.1 - 0.0019 17.6 0.0 0.31 10.4 0.0 2.7 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.3 EWM30432.1 - 0.0037 17.0 0.0 0.0085 15.9 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase PGAP1 PF07819.8 EWM30432.1 - 0.092 12.3 0.0 0.33 10.5 0.0 1.9 2 1 0 2 2 2 0 PGAP1-like protein Beach PF02138.13 EWM30433.1 - 2.2e-48 165.0 0.0 3e-48 164.6 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.27 EWM30433.1 - 2.6e-06 27.0 5.5 0.082 12.8 0.0 5.7 5 0 0 5 5 5 2 WD domain, G-beta repeat Pkinase PF00069.20 EWM30433.1 - 0.00088 18.4 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain BSP_II PF05432.6 EWM30433.1 - 0.0013 18.0 3.2 0.0013 18.0 2.2 2.0 3 0 0 3 3 3 1 Bone sialoprotein II (BSP-II) Nup160 PF11715.3 EWM30433.1 - 0.029 12.5 1.1 5.1 5.1 0.2 3.0 2 2 1 3 3 3 0 Nucleoporin Nup120/160 HAD_2 PF13419.1 EWM30434.1 - 7.9e-22 78.3 0.0 1.1e-21 77.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EWM30434.1 - 4.4e-09 35.9 0.0 9.5e-09 34.8 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EWM30434.1 - 7.3e-09 36.3 0.1 1.5e-07 32.0 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EWM30434.1 - 0.015 15.4 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Med7 PF05983.6 EWM30434.1 - 0.066 12.9 0.0 0.09 12.5 0.0 1.2 1 0 0 1 1 1 0 MED7 protein IMS PF00817.15 EWM30435.1 - 1.2e-39 135.5 0.0 2e-39 134.7 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EWM30435.1 - 2.1e-15 56.7 0.0 4.5e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain PrsW-protease PF13367.1 EWM30437.1 - 2.7e-05 23.4 2.2 0.0014 17.8 0.2 2.7 2 1 0 2 2 2 2 Protease prsW family THDPS_N_2 PF14805.1 EWM30438.1 - 0.084 12.7 2.1 0.25 11.2 1.4 1.8 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Peptidase_C78 PF07910.8 EWM30439.1 - 2.7e-38 131.2 0.0 3.9e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 DUF1648 PF07853.6 EWM30439.1 - 0.087 12.3 0.1 2.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1648) Peptidase_C78 PF07910.8 EWM30440.1 - 2e-38 131.7 0.0 3.1e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C78 DUF1648 PF07853.6 EWM30440.1 - 0.064 12.7 0.1 2.3 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1648) Aldo_ket_red PF00248.16 EWM30441.1 - 4.1e-44 150.5 0.0 4.8e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family TPR_7 PF13176.1 EWM30442.1 - 0.00028 20.4 15.3 0.42 10.5 0.6 5.9 7 0 0 7 7 7 3 Tetratricopeptide repeat Clathrin PF00637.15 EWM30442.1 - 0.00082 18.9 1.0 1.2 8.7 0.0 3.6 3 2 0 3 3 3 2 Region in Clathrin and VPS TPR_8 PF13181.1 EWM30442.1 - 0.0031 17.1 3.8 1.1 9.1 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EWM30442.1 - 0.015 15.2 17.8 0.14 12.0 0.2 5.7 4 3 0 5 5 5 0 Tetratricopeptide repeat SNAP PF14938.1 EWM30442.1 - 0.1 11.7 0.1 0.1 11.7 0.0 3.3 3 1 0 3 3 3 0 Soluble NSF attachment protein, SNAP Nic96 PF04097.9 EWM30442.1 - 0.22 9.6 2.7 9.8 4.1 0.0 3.7 4 0 0 4 4 4 0 Nup93/Nic96 TPR_1 PF00515.23 EWM30442.1 - 0.56 9.9 8.3 4.8 6.9 0.2 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EWM30442.1 - 0.83 9.7 23.9 1 9.4 0.1 7.1 8 1 0 8 8 8 0 Tetratricopeptide repeat O-FucT PF10250.4 EWM30443.1 - 6e-28 97.9 0.0 3.6e-27 95.3 0.0 2.1 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Form_Nir_trans PF01226.12 EWM30444.1 - 2.8e-66 222.9 25.2 3.5e-66 222.6 17.5 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter Mito_carr PF00153.22 EWM30445.1 - 5.6e-43 144.5 9.3 3.1e-17 62.0 0.0 4.7 5 0 0 5 5 5 4 Mitochondrial carrier protein EF-hand_6 PF13405.1 EWM30445.1 - 0.022 14.6 4.4 0.042 13.7 0.2 2.6 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.27 EWM30445.1 - 0.051 12.8 0.3 0.11 11.8 0.2 1.6 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.1 EWM30445.1 - 0.16 12.1 0.1 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair TPT PF03151.11 EWM30446.1 - 3.8e-11 42.8 8.1 3.8e-11 42.8 5.6 3.0 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EWM30446.1 - 1.4e-07 31.5 27.0 3.9e-07 30.1 6.0 2.4 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EWM30446.1 - 2e-05 24.7 5.0 2e-05 24.7 3.4 3.1 2 1 1 3 3 3 1 Multidrug resistance efflux transporter UAA PF08449.6 EWM30446.1 - 0.00014 20.8 21.0 0.00031 19.7 14.5 1.5 1 1 0 1 1 1 1 UAA transporter family Herpes_capsid PF06112.6 EWM30446.1 - 0.96 9.4 11.7 1.8 8.5 8.1 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein PCI PF01399.22 EWM30447.1 - 4.1e-08 33.4 0.0 1.3e-07 31.9 0.0 1.8 1 0 0 1 1 1 1 PCI domain Hrs_helical PF12210.3 EWM30447.1 - 0.044 14.0 1.2 0.09 13.0 0.8 1.5 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Peptidase_M16 PF00675.15 EWM30447.1 - 0.1 12.3 0.2 0.16 11.7 0.2 1.2 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) MIF4G_like PF09088.6 EWM30449.1 - 6.9e-14 51.7 0.0 1.2e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 EWM30449.1 - 1.9e-08 33.8 0.0 3.7e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 EWM30449.1 - 0.0001 21.8 0.0 0.00024 20.5 0.0 1.6 1 0 0 1 1 1 1 MIF4G domain DUF3368 PF11848.3 EWM30449.1 - 0.13 11.8 0.1 0.39 10.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3368) Pyr_redox_dim PF02852.17 EWM30450.1 - 1.5e-29 102.2 2.1 1e-28 99.5 0.3 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 EWM30450.1 - 8.3e-26 91.1 0.5 1.5e-25 90.2 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EWM30450.1 - 1.8e-14 53.8 2.7 3.7e-12 46.4 0.2 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EWM30450.1 - 1e-08 34.7 0.4 2.1e-08 33.6 0.3 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EWM30450.1 - 4.3e-07 28.7 4.2 0.0012 17.3 0.2 3.1 2 1 1 3 3 3 2 HI0933-like protein NAD_binding_8 PF13450.1 EWM30450.1 - 3.4e-06 26.9 0.7 0.0019 18.2 0.1 3.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EWM30450.1 - 2e-05 23.7 5.1 0.2 10.5 0.0 3.2 2 1 1 3 3 3 3 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EWM30450.1 - 9.4e-05 21.4 3.5 0.00027 19.9 0.3 2.8 3 0 0 3 3 3 1 FAD binding domain 3HCDH_N PF02737.13 EWM30450.1 - 0.00016 21.3 0.4 0.0023 17.5 0.1 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EWM30450.1 - 0.00057 18.9 1.8 0.25 10.2 0.1 2.6 2 1 1 3 3 3 2 Lycopene cyclase protein XdhC_C PF13478.1 EWM30450.1 - 0.019 15.2 0.1 0.81 9.9 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain Thi4 PF01946.12 EWM30450.1 - 0.027 13.5 0.2 0.45 9.5 0.0 2.2 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.16 EWM30450.1 - 0.028 13.9 0.1 0.67 9.5 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 EWM30450.1 - 0.11 12.4 0.1 0.72 9.8 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain GIDA PF01134.17 EWM30450.1 - 0.11 11.2 2.2 0.41 9.4 0.1 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A TPT PF03151.11 EWM30451.1 - 1.3e-29 102.8 2.3 1.3e-29 102.8 1.6 2.3 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EWM30451.1 - 4.8e-14 52.4 23.4 2.8e-08 33.8 1.9 2.4 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EWM30451.1 - 1.2e-06 27.7 9.9 3.1e-06 26.3 6.9 1.7 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.1 EWM30451.1 - 0.15 12.3 23.1 0.5 10.5 2.0 3.3 2 1 1 3 3 3 0 Multidrug resistance efflux transporter DUF373 PF04123.8 EWM30451.1 - 9.6 5.1 9.6 5.6 5.8 4.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF373) Myb_DNA-binding PF00249.26 EWM30452.1 - 2e-13 50.1 0.9 3.9e-13 49.2 0.6 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EWM30452.1 - 0.00039 20.4 0.1 0.00071 19.6 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain LysM PF01476.15 EWM30454.1 - 0.094 12.6 0.0 0.31 10.9 0.0 1.9 2 0 0 2 2 2 0 LysM domain Ras PF00071.17 EWM30455.1 - 1e-48 164.7 0.0 1.3e-48 164.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EWM30455.1 - 2.7e-16 60.1 0.0 5.4e-16 59.1 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EWM30455.1 - 1.8e-09 37.0 0.0 2.4e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 EWM30455.1 - 0.00014 22.0 0.0 0.00047 20.2 0.0 1.8 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 EWM30455.1 - 0.00028 20.1 0.0 0.00033 19.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EWM30455.1 - 0.02 14.8 0.0 0.042 13.7 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.5 EWM30455.1 - 0.029 13.5 0.0 0.053 12.7 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EWM30455.1 - 0.045 13.8 0.0 0.25 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 EWM30455.1 - 0.083 11.8 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Septin AAA_33 PF13671.1 EWM30455.1 - 0.12 12.2 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.15 EWM30455.1 - 0.2 10.3 1.1 1.5 7.4 0.0 2.4 2 1 1 3 3 3 0 G-protein alpha subunit zf-CCCH PF00642.19 EWM30456.1 - 3.6e-34 115.8 36.6 5.2e-10 38.7 3.8 4.4 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LRV_FeS PF05484.6 EWM30456.1 - 0.64 9.6 9.7 5.3 6.6 0.3 3.8 4 0 0 4 4 4 0 LRV protein FeS4 cluster zf-CCCH PF00642.19 EWM30457.1 - 7.9e-20 70.0 20.6 3.6e-10 39.2 3.8 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LRV_FeS PF05484.6 EWM30457.1 - 0.027 14.0 2.7 3.8 7.1 0.3 2.6 2 0 0 2 2 2 0 LRV protein FeS4 cluster O-FucT PF10250.4 EWM30459.1 - 4.9e-15 55.4 0.9 2.3e-08 33.5 0.0 2.7 1 1 1 2 2 2 2 GDP-fucose protein O-fucosyltransferase DUF1279 PF06916.8 EWM30460.1 - 1.9e-22 79.3 1.3 3e-22 78.6 0.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1279) Proteasome PF00227.21 EWM30461.1 - 1.8e-27 95.8 0.2 3.2e-27 95.0 0.1 1.4 1 1 0 1 1 1 1 Proteasome subunit Hep_59 PF07052.6 EWM30462.1 - 1.4e-08 35.0 0.1 1.4e-08 35.0 0.0 2.9 1 1 1 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 DUF1336 PF07059.7 EWM30463.1 - 2.3e-39 135.1 0.0 3.7e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) PX PF00787.19 EWM30463.1 - 2.1e-15 56.5 0.0 3.8e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 PX domain Glyco_transf_64 PF09258.5 EWM30464.1 - 1.2e-58 198.1 0.0 1.7e-28 99.4 0.0 2.0 2 0 0 2 2 2 2 Glycosyl transferase family 64 domain BTK PF00779.14 EWM30465.1 - 0.00049 19.6 1.4 0.00049 19.6 1.0 3.1 3 0 0 3 3 3 1 BTK motif CHORD PF04968.7 EWM30465.1 - 0.016 15.4 4.4 0.016 15.4 3.0 2.6 1 1 1 2 2 2 0 CHORD Rpr2 PF04032.11 EWM30465.1 - 0.025 14.4 0.6 0.037 13.8 0.4 1.3 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DCP1 PF06058.8 EWM30466.1 - 0.0089 16.0 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family Abhydrolase_6 PF12697.2 EWM30467.1 - 8.7e-27 94.4 0.2 1.3e-26 93.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM30467.1 - 1.7e-11 44.0 0.0 3.2e-11 43.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EWM30467.1 - 0.0022 17.6 0.0 0.0087 15.6 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EWM30467.1 - 0.011 15.5 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase DUF2305 PF10230.4 EWM30467.1 - 0.028 13.8 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 EWM30468.1 - 2e-23 83.4 0.0 2.8e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EWM30468.1 - 3.7e-10 39.7 0.0 5.7e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EWM30468.1 - 0.0066 16.0 0.0 0.0087 15.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EWM30468.1 - 0.0083 15.9 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DUF2305 PF10230.4 EWM30468.1 - 0.023 14.0 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Glyco_transf_15 PF01793.11 EWM30469.1 - 4.3e-56 190.2 0.1 1.8e-48 165.1 0.0 3.9 4 0 0 4 4 4 3 Glycolipid 2-alpha-mannosyltransferase Methyltransf_22 PF13383.1 EWM30469.1 - 3.8e-33 115.0 0.0 6.6e-33 114.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.7 EWM30469.1 - 0.0021 17.9 0.0 0.0076 16.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase FkbM domain adh_short PF00106.20 EWM30471.1 - 5.9e-30 104.3 1.6 6.8e-30 104.1 0.1 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EWM30471.1 - 9.4e-14 51.4 0.1 1.6e-13 50.7 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EWM30471.1 - 2.5e-08 33.9 0.0 3.5e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EWM30471.1 - 0.00011 22.2 1.4 0.00016 21.7 0.1 1.8 2 0 0 2 2 2 1 NADH(P)-binding DUF1776 PF08643.5 EWM30471.1 - 0.035 13.2 0.0 0.12 11.4 0.0 1.8 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EWM30471.1 - 0.072 12.5 0.0 0.18 11.2 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family UAA PF08449.6 EWM30472.1 - 1.9e-82 276.6 7.6 2.5e-82 276.2 5.2 1.1 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 EWM30472.1 - 1.6e-06 27.4 3.4 2.3e-06 26.9 2.4 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 EWM30472.1 - 1.5e-05 25.0 14.4 0.00037 20.5 4.3 2.4 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 EWM30472.1 - 0.0047 16.5 11.7 0.0099 15.5 8.1 1.5 1 0 0 1 1 1 1 Triose-phosphate Transporter family PNTB PF02233.11 EWM30473.1 - 6.6e-172 572.4 16.6 6.6e-172 572.4 11.5 1.9 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit DUF3814 PF12769.2 EWM30473.1 - 3.3e-27 94.4 4.9 3.3e-27 94.4 3.4 3.5 4 0 0 4 4 4 1 Domain of unknown function (DUF3814) AlaDh_PNT_C PF01262.16 EWM30473.1 - 4.4e-22 78.4 0.0 1.2e-21 77.0 0.0 1.8 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TPP_enzyme_M PF00205.17 EWM30473.1 - 5.1e-07 29.5 0.1 2.7e-06 27.1 0.1 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Peptidase_M24 PF00557.19 EWM30474.1 - 8.2e-49 165.9 0.1 9.9e-49 165.7 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 FAM92 PF06730.6 EWM30475.1 - 7.1e-09 35.3 5.4 8.3e-09 35.0 3.7 1.1 1 0 0 1 1 1 1 FAM92 protein Vps5 PF09325.5 EWM30475.1 - 2.1e-05 23.9 6.3 9.9e-05 21.7 0.4 2.4 3 0 0 3 3 3 2 Vps5 C terminal like GidB PF02527.10 EWM30475.1 - 0.021 13.9 1.6 0.023 13.8 0.3 1.6 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G Imm43 PF15602.1 EWM30475.1 - 0.033 14.1 0.3 0.76 9.7 0.2 2.2 1 1 0 1 1 1 0 Immunity protein 43 FA_desaturase_2 PF03405.9 EWM30476.1 - 5.7e-127 423.0 0.0 6.3e-127 422.8 0.0 1.0 1 0 0 1 1 1 1 Fatty acid desaturase Phenol_Hydrox PF02332.13 EWM30476.1 - 0.001 18.4 0.0 0.0023 17.2 0.0 1.6 2 0 0 2 2 2 1 Methane/Phenol/Toluene Hydroxylase Rubrerythrin PF02915.12 EWM30476.1 - 0.12 12.6 0.0 13 6.1 0.0 2.3 2 0 0 2 2 2 0 Rubrerythrin PH_11 PF15413.1 EWM30477.1 - 0.015 15.5 3.0 0.077 13.2 1.0 2.9 2 1 0 2 2 2 0 Pleckstrin homology domain GlcNAc PF11397.3 EWM30478.1 - 6.5e-74 249.0 0.0 8.4e-74 248.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) UDPGP PF01704.13 EWM30479.1 - 1.2e-145 485.2 0.0 1.4e-145 485.0 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Rubis-subs-bind PF09273.6 EWM30480.1 - 2.4e-19 69.5 0.0 3.7e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.23 EWM30480.1 - 0.0033 17.7 0.0 3.8 7.7 0.0 2.5 2 0 0 2 2 2 2 SET domain Pex24p PF06398.6 EWM30482.1 - 0.1 11.3 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin B_lectin PF01453.19 EWM30483.1 - 0.013 15.3 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 D-mannose binding lectin dCMP_cyt_deam_1 PF00383.17 EWM30484.1 - 1.1e-22 79.5 0.4 2.1e-22 78.7 0.3 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EWM30484.1 - 0.00013 21.8 2.5 0.0014 18.5 1.7 2.1 1 1 0 1 1 1 1 Bd3614-like deaminase APOBEC_N PF08210.6 EWM30484.1 - 0.035 13.7 0.1 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 APOBEC-like N-terminal domain DUF4575 PF15143.1 EWM30486.1 - 0.0072 16.0 0.7 0.0072 16.0 0.5 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4575) adh_short PF00106.20 EWM30487.1 - 6e-21 75.0 0.2 6.8e-19 68.3 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EWM30487.1 - 4.7e-08 32.9 0.2 9.9e-08 31.8 0.1 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EWM30487.1 - 1e-07 31.9 0.0 1.8e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EWM30487.1 - 0.0045 16.4 0.0 0.0068 15.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EWM30487.1 - 0.077 12.9 0.1 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 NADH(P)-binding adh_short PF00106.20 EWM30488.1 - 6e-21 75.0 0.2 6.8e-19 68.3 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EWM30488.1 - 4.7e-08 32.9 0.2 9.9e-08 31.8 0.1 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EWM30488.1 - 1e-07 31.9 0.0 1.8e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EWM30488.1 - 0.0045 16.4 0.0 0.0068 15.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EWM30488.1 - 0.077 12.9 0.1 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 NADH(P)-binding UPF0054 PF02130.12 EWM30489.1 - 1.7e-28 98.7 7.3 3.4e-17 62.0 0.0 2.9 3 0 0 3 3 2 2 Uncharacterized protein family UPF0054 CDC45 PF02724.9 EWM30489.1 - 0.04 11.9 8.4 0.049 11.6 5.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Ras_bdg_2 PF14847.1 EWM30489.1 - 0.059 13.2 0.1 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Ras-binding domain of Byr2 DUF4391 PF14335.1 EWM30489.1 - 0.19 11.0 3.3 0.29 10.4 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) DGF-1_C PF11040.3 EWM30489.1 - 0.27 11.1 5.8 0.57 10.0 0.1 2.7 1 1 1 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Daxx PF03344.10 EWM30489.1 - 0.36 9.2 17.9 0.54 8.6 12.4 1.3 1 0 0 1 1 1 0 Daxx Family PVL_ORF50 PF07768.6 EWM30489.1 - 0.56 10.2 12.0 0.52 10.3 7.4 1.6 1 1 0 1 1 1 0 PVL ORF-50-like family BUD22 PF09073.5 EWM30489.1 - 0.56 9.2 19.9 0.88 8.5 13.8 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 EWM30489.1 - 0.58 8.0 22.8 0.79 7.5 15.8 1.1 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.6 EWM30489.1 - 1.1 8.7 19.6 2 7.8 13.6 1.3 1 0 0 1 1 1 0 PPP4R2 Voldacs PF03517.8 EWM30489.1 - 5.1 6.9 14.0 11 5.8 9.7 1.6 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling Radical_SAM PF04055.16 EWM30490.1 - 6.8e-07 29.5 0.0 1.3e-06 28.6 0.0 1.5 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 EWM30490.1 - 0.097 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S single cluster domain WD40 PF00400.27 EWM30491.1 - 5.6e-73 238.4 4.8 1.8e-10 40.3 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EWM30491.1 - 5.6e-07 28.0 3.3 0.002 16.3 0.0 3.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF3312 PF11768.3 EWM30491.1 - 0.0033 15.7 0.0 0.011 14.0 0.0 1.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3312) 2OG-FeII_Oxy_3 PF13640.1 EWM30492.1 - 0.006 17.0 1.3 0.019 15.4 0.0 2.4 3 0 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily zf-SAP30 PF13866.1 EWM30493.1 - 0.047 13.3 0.4 0.057 13.0 0.3 1.2 1 0 0 1 1 1 0 SAP30 zinc-finger TT_ORF1 PF02956.9 EWM30493.1 - 1.9 6.8 7.4 1.9 6.8 5.1 1.0 1 0 0 1 1 1 0 TT viral orf 1 CTDII PF01556.13 EWM30495.1 - 1.3e-25 89.0 0.3 6e-21 74.1 0.0 3.3 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 EWM30495.1 - 2.4e-23 81.6 0.6 4.2e-23 80.8 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EWM30495.1 - 0.0013 18.7 5.6 0.0026 17.7 3.8 1.5 1 0 0 1 1 1 1 DnaJ central domain DUF4336 PF14234.1 EWM30496.1 - 5.6e-19 68.4 0.0 1.1e-16 60.8 0.0 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4336) Chloroa_b-bind PF00504.16 EWM30498.1 - 3e-32 112.0 0.1 4.1e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein TTL PF03133.10 EWM30499.1 - 1e-40 139.5 0.0 1.6e-40 138.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATP-grasp_4 PF13535.1 EWM30499.1 - 0.0047 16.6 0.0 0.011 15.4 0.0 1.6 1 1 1 2 2 2 1 ATP-grasp domain CAF1 PF04857.15 EWM30500.1 - 1.8e-50 171.7 0.0 3.1e-50 170.9 0.0 1.4 1 1 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.15 EWM30500.1 - 0.00083 18.8 0.0 0.33 10.4 0.0 2.3 2 0 0 2 2 2 2 3'-5' exonuclease Ank_2 PF12796.2 EWM30501.1 - 1.6e-37 127.6 0.1 3.5e-20 72.1 0.0 3.3 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EWM30501.1 - 1.1e-34 116.5 4.6 1e-06 28.2 0.0 7.4 7 0 0 7 7 7 5 Ankyrin repeat zf-DHHC PF01529.15 EWM30501.1 - 5.7e-34 117.0 0.8 1.1e-33 116.0 0.5 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase Ank_4 PF13637.1 EWM30501.1 - 4.3e-29 100.3 0.1 1.4e-10 41.3 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EWM30501.1 - 6.3e-28 96.1 5.5 3.7e-10 39.6 0.1 5.4 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM30501.1 - 3.5e-27 91.7 0.4 0.00011 22.0 0.0 7.5 7 0 0 7 7 7 4 Ankyrin repeat 2-Hacid_dh_C PF02826.14 EWM30503.1 - 9.3e-61 204.0 0.0 2.1e-60 202.8 0.0 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EWM30503.1 - 3.5e-31 107.4 0.0 5.8e-31 106.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.20 EWM30503.1 - 7.7e-08 31.6 0.1 4.6e-07 29.1 0.0 2.4 2 0 0 2 2 2 1 ACT domain IlvN PF07991.7 EWM30503.1 - 0.00066 19.0 0.0 0.0015 17.9 0.0 1.6 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 EWM30503.1 - 0.0015 18.4 0.0 0.0058 16.4 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT_4 PF13291.1 EWM30503.1 - 0.0069 16.6 0.0 0.02 15.1 0.0 1.8 1 0 0 1 1 1 1 ACT domain AdoHcyase_NAD PF00670.16 EWM30503.1 - 0.0086 15.9 0.1 0.038 13.8 0.0 2.1 2 1 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Aminotran_5 PF00266.14 EWM30504.1 - 1.7e-25 89.5 0.0 1.8e-13 50.0 0.0 3.2 1 1 0 2 2 2 2 Aminotransferase class-V MOSC_N PF03476.11 EWM30504.1 - 4.4e-22 78.0 0.0 9.1e-22 77.0 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EWM30504.1 - 3.9e-13 49.0 0.0 3.8e-12 45.8 0.0 2.3 1 1 0 1 1 1 1 MOSC domain DUF2163 PF09931.4 EWM30504.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2163) SNF2_N PF00176.18 EWM30505.1 - 1.8e-56 191.1 0.0 2.8e-56 190.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EWM30505.1 - 2.7e-15 55.9 0.0 8e-15 54.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EWM30505.1 - 2e-05 24.1 0.0 3.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Lipase_3 PF01764.20 EWM30506.1 - 4.2e-14 52.3 0.0 6.8e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EWM30506.1 - 0.0069 16.2 1.0 0.0097 15.8 0.1 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EWM30506.1 - 0.13 11.7 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold ParA PF10609.4 EWM30507.1 - 3.8e-31 106.7 0.1 6.6e-31 106.0 0.1 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EWM30507.1 - 1.3e-19 70.4 0.0 2.5e-19 69.4 0.0 1.5 1 1 1 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EWM30507.1 - 8.9e-07 28.9 0.0 3.8e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 EWM30507.1 - 9.9e-07 28.0 2.0 5.3e-06 25.7 0.1 2.5 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 EWM30507.1 - 2.6e-05 23.7 0.0 4.4e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain MipZ PF09140.6 EWM30507.1 - 8.2e-05 21.8 0.0 0.00034 19.8 0.0 1.9 1 1 0 1 1 1 1 ATPase MipZ AAA_19 PF13245.1 EWM30507.1 - 0.00036 20.2 0.2 0.019 14.7 0.0 2.6 2 1 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 EWM30507.1 - 0.00039 20.1 0.5 0.00061 19.4 0.3 1.2 1 0 0 1 1 1 1 NACHT domain DnaB_C PF03796.10 EWM30507.1 - 0.013 14.4 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain SRP54 PF00448.17 EWM30507.1 - 0.026 13.9 0.2 0.056 12.8 0.0 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NB-ARC PF00931.17 EWM30507.1 - 0.036 12.9 0.1 0.058 12.2 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain DUF258 PF03193.11 EWM30507.1 - 0.041 13.0 0.1 0.086 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 EWM30507.1 - 0.042 14.6 0.0 0.084 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EWM30507.1 - 0.059 12.7 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein UPF0079 PF02367.12 EWM30507.1 - 0.18 11.4 0.1 0.3 10.7 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ubiquitin PF00240.18 EWM30508.1 - 2.5e-16 58.8 0.0 4.1e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EWM30508.1 - 0.00012 21.6 0.0 0.00021 20.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EWM30508.1 - 0.0023 17.8 0.0 0.004 17.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EWM30508.1 - 0.0076 16.4 0.0 0.018 15.2 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.4 EWM30508.1 - 0.052 13.7 0.0 0.082 13.1 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 EWM30509.1 - 2.5e-16 58.8 0.0 4.1e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EWM30509.1 - 0.00012 21.6 0.0 0.00021 20.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EWM30509.1 - 0.0011 18.8 0.0 0.004 17.0 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EWM30509.1 - 0.0075 16.5 0.0 0.018 15.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.4 EWM30509.1 - 0.053 13.7 0.0 0.081 13.1 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain ArfGap PF01412.13 EWM30510.1 - 9.4e-34 115.7 0.0 1.9e-33 114.7 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Peptidase_M24 PF00557.19 EWM30511.1 - 1.7e-42 145.3 0.6 3.1e-42 144.5 0.1 1.7 2 0 0 2 2 2 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EWM30511.1 - 1.8e-20 73.7 0.0 2.4e-17 63.6 0.0 3.1 2 1 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Pam16 PF03656.8 EWM30512.1 - 3.3e-23 81.8 1.8 4.2e-23 81.5 1.3 1.1 1 0 0 1 1 1 1 Pam16 Acid_PPase PF12689.2 EWM30512.1 - 0.04 13.5 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 Acid Phosphatase Med2 PF11214.3 EWM30512.1 - 1.7 8.7 5.7 0.83 9.7 2.3 1.7 2 0 0 2 2 2 0 Mediator complex subunit 2 Thioredoxin PF00085.15 EWM30513.1 - 1.1e-30 105.3 0.1 1.2e-30 105.2 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EWM30513.1 - 7.5e-09 35.6 0.0 1.1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EWM30513.1 - 3.2e-07 30.5 0.2 2.7e-06 27.5 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EWM30513.1 - 3.3e-07 30.0 0.1 3.8e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EWM30513.1 - 2.4e-06 27.1 0.1 2.8e-06 26.9 0.1 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.1 EWM30513.1 - 6.6e-05 22.8 0.1 0.0001 22.2 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EWM30513.1 - 0.011 15.3 0.0 0.011 15.3 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Glutaredoxin PF00462.19 EWM30513.1 - 0.027 14.4 0.2 0.039 13.9 0.1 1.4 1 1 0 1 1 1 0 Glutaredoxin HyaE PF07449.6 EWM30513.1 - 0.098 12.5 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE zf-DHHC PF01529.15 EWM30515.1 - 7.9e-31 106.7 5.4 7.9e-31 106.7 3.7 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase Response_reg PF00072.19 EWM30516.1 - 2.9e-20 72.3 0.2 4.9e-20 71.6 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 EWM30516.1 - 1.6e-19 69.6 0.0 1.8e-10 40.5 0.0 2.4 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EWM30516.1 - 2e-12 46.9 0.0 4e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Daxx PF03344.10 EWM30516.1 - 0.017 13.6 20.0 0.025 13.0 13.8 1.1 1 0 0 1 1 1 0 Daxx Family NRPS PF08415.5 EWM30516.1 - 0.02 14.6 0.0 0.056 13.2 0.0 1.8 1 0 0 1 1 1 0 Nonribosomal peptide synthase PPP4R2 PF09184.6 EWM30516.1 - 0.21 11.1 12.7 0.34 10.4 8.8 1.2 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.7 EWM30516.1 - 0.86 7.4 25.3 1.3 6.8 17.5 1.1 1 0 0 1 1 1 0 Nop14-like family CENP-T PF15511.1 EWM30516.1 - 1.7 7.8 12.7 3.2 6.9 8.8 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Sporozoite_P67 PF05642.6 EWM30516.1 - 2 6.1 6.4 3.8 5.2 4.4 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF1510 PF07423.6 EWM30516.1 - 3 7.1 19.6 8.5 5.6 13.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Syntaxin-6_N PF09177.6 EWM30517.1 - 0.1 13.0 2.9 0.83 10.0 2.0 2.1 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Seryl_tRNA_N PF02403.17 EWM30517.1 - 0.17 11.9 5.4 1.5 8.8 0.4 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain MT0933_antitox PF14013.1 EWM30517.1 - 0.36 10.9 2.6 2.1 8.5 1.8 2.2 1 1 0 1 1 1 0 MT0933-like antitoxin protein tRNA-synt_1e PF01406.14 EWM30518.1 - 7.7e-106 353.5 0.0 9.7e-106 353.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EWM30518.1 - 3.7e-12 45.6 0.0 1.1e-05 24.3 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.6 EWM30518.1 - 1.8e-11 44.1 0.0 4.3e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 DALR domain tRNA-synt_1f PF01921.13 EWM30518.1 - 4.8e-05 22.2 0.0 0.14 10.8 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (K) CS PF04969.11 EWM30519.1 - 3.3e-19 69.2 0.0 6.3e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 CS domain Nudc_N PF14050.1 EWM30519.1 - 2.6e-18 65.6 0.0 7.1e-18 64.3 0.0 1.7 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. MRP-S33 PF08293.6 EWM30519.1 - 3.2 7.7 7.3 0.34 10.9 1.7 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit S27 Fer4_13 PF13370.1 EWM30520.1 - 2e-10 40.8 0.0 3.3e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_15 PF13459.1 EWM30520.1 - 6.1e-07 29.9 0.1 1.1e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_10 PF13237.1 EWM30520.1 - 0.0023 17.7 0.4 0.0041 16.8 0.3 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 EWM30520.1 - 0.0032 17.8 0.3 0.11 12.9 0.1 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EWM30520.1 - 0.0044 17.0 0.1 0.009 16.0 0.1 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.1 EWM30520.1 - 0.0071 16.6 0.2 0.024 14.9 0.1 1.8 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4 PF00037.22 EWM30520.1 - 0.013 15.1 6.2 0.067 12.8 2.5 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_9 PF13187.1 EWM30520.1 - 0.015 15.5 0.3 0.058 13.6 0.1 1.9 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 EWM30520.1 - 0.016 15.1 2.5 0.032 14.1 1.7 1.5 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_4 PF12800.2 EWM30520.1 - 0.026 14.8 1.4 0.026 14.8 1.0 1.7 2 0 0 2 2 1 0 4Fe-4S binding domain Fer4_18 PF13746.1 EWM30520.1 - 0.035 14.5 0.3 0.082 13.3 0.2 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_21 PF14697.1 EWM30520.1 - 0.064 13.1 0.4 0.064 13.1 0.3 1.5 2 0 0 2 2 1 0 4Fe-4S dicluster domain Fer4_16 PF13484.1 EWM30520.1 - 0.068 13.9 0.2 0.81 10.4 0.1 2.2 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Lactamase_B PF00753.22 EWM30520.1 - 0.071 12.7 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Fer4_19 PF06902.6 EWM30520.1 - 0.12 12.1 0.1 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Fer4_6 PF12837.2 EWM30520.1 - 0.3 11.0 5.9 0.67 9.9 1.6 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.2 EWM30520.1 - 3.2 8.5 7.4 4.2 8.1 2.9 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain DEAD PF00270.24 EWM30521.1 - 1.1e-45 155.1 0.0 1.9e-45 154.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EWM30521.1 - 8.4e-23 80.0 0.0 1.6e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EWM30521.1 - 0.041 13.7 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ALMT PF11744.3 EWM30522.1 - 5.8e-08 31.8 6.0 5.8e-08 31.8 4.2 2.6 3 1 0 3 3 3 1 Aluminium activated malate transporter FUSC_2 PF13515.1 EWM30522.1 - 8.4e-08 32.1 11.9 8.4e-08 32.1 8.3 2.5 2 0 0 2 2 2 1 Fusaric acid resistance protein-like Rick_17kDa_Anti PF05433.10 EWM30522.1 - 0.08 12.6 0.2 0.18 11.5 0.2 1.6 1 0 0 1 1 1 0 Glycine zipper 2TM domain DUF939 PF06081.6 EWM30522.1 - 3 7.7 15.6 0.13 12.1 4.1 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF939) DUF547 PF04784.9 EWM30523.1 - 1.7e-15 56.9 0.0 6e-15 55.1 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF547 Tom37_C PF11801.3 EWM30523.1 - 0.21 11.4 0.9 0.9 9.3 0.7 1.9 2 0 0 2 2 2 0 Tom37 C-terminal domain RNA_polI_A34 PF08208.6 EWM30523.1 - 0.25 10.9 6.1 0.5 10.0 4.2 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 LIN37 PF15306.1 EWM30523.1 - 1.5 8.7 10.6 0.34 10.9 2.6 2.7 2 0 0 2 2 2 0 LIN37 Ycf1 PF05758.7 EWM30523.1 - 1.7 6.2 1.9 2.3 5.8 1.3 1.1 1 0 0 1 1 1 0 Ycf1 CYSTM PF12734.2 EWM30524.1 - 0.0038 17.2 1.7 0.15 12.1 0.1 3.0 2 0 0 2 2 2 1 Cysteine-rich TM module stress tolerance DUF3328 PF11807.3 EWM30524.1 - 0.066 12.8 0.1 0.11 12.1 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) HAD_2 PF13419.1 EWM30525.1 - 1.2e-13 51.6 0.1 2.2e-13 50.8 0.1 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EWM30525.1 - 5.1e-05 22.9 0.1 0.0001 21.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like SNARE PF05739.14 EWM30526.1 - 1.2e-16 60.1 5.0 1.2e-16 60.1 3.5 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EWM30526.1 - 4.5e-06 26.7 4.5 2e-05 24.7 0.1 2.7 2 1 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 EWM30526.1 - 0.00056 19.5 2.0 0.049 13.1 1.2 2.4 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Ku_PK_bind PF08785.6 EWM30526.1 - 0.14 12.1 1.3 0.22 11.4 0.1 1.9 2 0 0 2 2 2 0 Ku C terminal domain like DSPc PF00782.15 EWM30527.1 - 9e-30 102.9 0.0 1.7e-29 102.0 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EWM30527.1 - 0.02 14.2 0.2 0.084 12.1 0.0 2.0 2 0 0 2 2 2 0 Protein-tyrosine phosphatase DUF399 PF04187.8 EWM30528.1 - 4.9e-51 173.2 0.6 6.3e-51 172.8 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF399 Erythro_esteras PF05139.9 EWM30528.1 - 0.013 14.6 0.0 0.03 13.5 0.0 1.5 2 0 0 2 2 2 0 Erythromycin esterase GFA PF04828.9 EWM30529.1 - 0.00053 19.8 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Auto_anti-p27 PF06677.7 EWM30529.1 - 0.01 15.5 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) AMP-binding PF00501.23 EWM30530.1 - 2.4e-42 144.7 0.0 3.6e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme RRM_1 PF00076.17 EWM30531.1 - 1.6e-17 62.9 0.0 3.9e-17 61.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM30531.1 - 4.7e-16 58.5 0.0 8.4e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM30531.1 - 1.1e-07 31.5 0.0 1.7e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SpoIIIAH PF12685.2 EWM30531.1 - 0.039 13.4 5.7 0.053 13.0 3.9 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Cut12 PF11500.3 EWM30531.1 - 0.05 13.2 0.4 0.088 12.4 0.3 1.3 1 0 0 1 1 1 0 Spindle pole body formation-associated protein Pox_A_type_inc PF04508.7 EWM30531.1 - 0.5 10.2 3.6 1 9.3 2.5 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat CDC27 PF09507.5 EWM30531.1 - 0.55 9.3 4.6 0.68 9.0 3.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 NAD_binding_10 PF13460.1 EWM30532.1 - 2.7e-30 105.7 0.0 3.9e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EWM30532.1 - 8.2e-08 31.2 0.0 0.0001 21.1 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EWM30532.1 - 3.5e-07 29.7 0.0 0.0014 17.9 0.0 2.4 2 0 0 2 2 2 2 NmrA-like family Epimerase PF01370.16 EWM30532.1 - 1.2e-05 24.8 0.0 0.027 13.9 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EWM30532.1 - 6.6e-05 22.8 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain Semialdhyde_dh PF01118.19 EWM30532.1 - 0.00036 20.8 0.0 0.0023 18.2 0.0 2.1 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EWM30532.1 - 0.00056 19.8 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.10 EWM30532.1 - 0.0014 17.6 0.0 0.14 10.9 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 EWM30532.1 - 0.0081 15.1 0.1 0.011 14.6 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 EWM30532.1 - 0.021 14.7 0.3 0.066 13.1 0.1 1.9 2 0 0 2 2 2 0 short chain dehydrogenase CHASE2 PF05226.6 EWM30532.1 - 0.095 11.9 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 CHASE2 domain WD40 PF00400.27 EWM30533.1 - 4e-51 169.1 13.9 7.6e-14 50.9 0.9 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EWM30533.1 - 6e-30 104.1 0.1 9e-30 103.6 0.1 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit eIF2A PF08662.6 EWM30533.1 - 0.00013 21.7 0.0 0.0073 16.0 0.0 2.4 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EWM30533.1 - 0.0038 15.4 0.2 0.33 9.0 0.0 2.4 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 EWM30533.1 - 0.034 13.2 1.5 6.8 5.7 0.0 3.4 2 1 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal LZ_Tnp_IS481 PF13011.1 EWM30533.1 - 0.083 13.2 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 Arm PF00514.18 EWM30534.1 - 6.7e-09 35.2 1.7 0.0011 18.6 0.0 4.2 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat RRM_1 PF00076.17 EWM30536.1 - 1.2e-20 72.9 0.0 4.4e-14 51.8 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM30536.1 - 2.2e-15 56.3 0.0 1.5e-11 44.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM30536.1 - 5.7e-06 26.0 0.0 0.00067 19.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EWM30537.1 - 7.3e-11 41.5 9.1 0.15 11.9 0.1 8.0 8 0 0 8 8 8 4 WD domain, G-beta repeat HEAT PF02985.17 EWM30537.1 - 2e-08 33.6 0.5 0.46 10.7 0.0 5.1 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.1 EWM30537.1 - 0.0026 17.9 0.0 7.8 6.8 0.0 3.6 3 0 0 3 3 3 1 HEAT repeats Apc5 PF12862.2 EWM30538.1 - 1.5e-24 85.6 2.0 6.1e-24 83.6 0.2 2.7 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_14 PF13428.1 EWM30538.1 - 0.0049 17.3 20.3 0.0066 16.9 0.3 6.7 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 EWM30538.1 - 0.0056 16.5 11.4 0.36 10.8 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.9 EWM30538.1 - 1.8 9.2 19.1 0.67 10.5 0.5 5.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Ank_2 PF12796.2 EWM30539.1 - 1.3e-11 44.6 0.1 2.6e-11 43.7 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EWM30539.1 - 2.9e-07 29.9 0.1 1.5e-06 27.7 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 EWM30539.1 - 8e-06 26.2 0.0 1.9e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EWM30539.1 - 0.00038 20.6 0.1 0.0051 17.0 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EWM30539.1 - 0.0029 17.6 0.0 0.0083 16.2 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat SNARE PF05739.14 EWM30540.1 - 2.5e-15 55.9 1.1 2.5e-15 55.9 0.8 2.6 3 1 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EWM30540.1 - 6.8e-12 45.4 1.4 6.8e-12 45.4 0.9 2.2 2 0 0 2 2 2 1 Syntaxin Prominin PF05478.6 EWM30540.1 - 1.9e-05 22.4 5.3 2.4e-05 22.0 3.7 1.0 1 0 0 1 1 1 1 Prominin Syntaxin_2 PF14523.1 EWM30540.1 - 0.00015 21.7 6.7 0.15 12.1 1.2 3.0 2 1 1 3 3 3 2 Syntaxin-like protein SCP-1 PF05483.7 EWM30540.1 - 0.0016 16.3 0.6 0.0016 16.3 0.4 1.5 2 0 0 2 2 2 1 Synaptonemal complex protein 1 (SCP-1) MutS_III PF05192.13 EWM30540.1 - 0.016 14.9 0.1 0.025 14.3 0.1 1.3 1 0 0 1 1 1 0 MutS domain III DUF1554 PF07588.6 EWM30540.1 - 0.086 12.3 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1554) Sec5 PF15469.1 EWM30540.1 - 0.14 11.8 10.6 3.1 7.4 7.2 2.6 1 1 0 1 1 1 0 Exocyst complex component Sec5 T2SF PF00482.18 EWM30540.1 - 0.19 11.6 2.1 1.2 9.1 0.1 2.8 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein F RGS PF00615.14 EWM30540.1 - 0.54 10.3 4.0 1.3 9.1 0.2 2.5 1 1 2 3 3 3 0 Regulator of G protein signaling domain Amnionless PF14828.1 EWM30540.1 - 2.9 6.2 7.8 0.83 8.0 0.5 2.5 1 1 2 3 3 3 0 Amnionless Malate_synthase PF01274.17 EWM30541.1 - 2.7e-70 236.8 0.0 1.8e-32 112.0 0.0 4.1 4 0 0 4 4 4 4 Malate synthase p450 PF00067.17 EWM30542.1 - 1.9e-70 237.7 0.0 2.3e-70 237.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_transf_34 PF05637.7 EWM30543.1 - 0.00036 20.1 0.0 0.00083 18.9 0.0 1.6 2 0 0 2 2 2 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 EWM30543.1 - 0.058 12.6 0.0 0.089 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF273 Epimerase PF01370.16 EWM30544.1 - 1.3e-59 201.4 0.1 1.7e-59 201.1 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EWM30544.1 - 1.7e-21 76.1 0.0 2.4e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EWM30544.1 - 4.1e-21 75.1 0.0 7.8e-16 57.8 0.0 2.0 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EWM30544.1 - 9e-19 67.3 0.1 3.3e-18 65.5 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EWM30544.1 - 5.9e-17 61.4 0.0 9.4e-17 60.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EWM30544.1 - 4.1e-05 23.6 0.0 0.00011 22.3 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EWM30544.1 - 0.0036 17.2 0.0 0.0036 17.2 0.0 2.8 4 1 1 5 5 5 1 short chain dehydrogenase WD40 PF00400.27 EWM30546.1 - 4.4e-14 51.7 1.1 1.8e-05 24.4 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EWM30546.1 - 0.0013 18.2 0.0 0.0028 17.1 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain FKBP_C PF00254.23 EWM30547.1 - 7.9e-18 64.2 0.0 1.1e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Oxidored_FMN PF00724.15 EWM30548.1 - 1.9e-81 273.7 0.0 2.2e-81 273.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family 2-ph_phosp PF04029.9 EWM30548.1 - 0.00089 18.2 0.0 0.0017 17.3 0.0 1.3 1 0 0 1 1 1 1 2-phosphosulpholactate phosphatase PPR PF01535.15 EWM30549.1 - 3.5e-17 61.1 3.2 0.03 14.3 0.0 8.2 8 1 0 8 8 8 4 PPR repeat PPR_2 PF13041.1 EWM30549.1 - 6e-16 58.1 0.2 0.047 13.6 0.0 8.8 9 1 1 10 10 10 4 PPR repeat family PPR_3 PF13812.1 EWM30549.1 - 3.1e-10 39.4 11.1 2.7 8.5 0.0 8.8 9 0 0 9 9 9 4 Pentatricopeptide repeat domain PPR_1 PF12854.2 EWM30549.1 - 0.00097 18.5 0.1 12 5.4 0.0 5.2 5 0 0 5 5 5 1 PPR repeat Smr PF01713.16 EWM30549.1 - 0.0053 16.9 0.0 0.21 11.7 0.0 3.0 2 0 0 2 2 2 1 Smr domain TPR_14 PF13428.1 EWM30549.1 - 0.011 16.2 5.8 19 6.2 0.2 5.7 4 0 0 4 4 4 0 Tetratricopeptide repeat CytochromB561_N PF09786.4 EWM30550.1 - 2.5e-15 55.9 0.0 7.2e-14 51.1 0.0 2.1 2 0 0 2 2 2 2 Cytochrome B561, N terminal Kinesin PF00225.18 EWM30551.1 - 2.7e-87 292.6 0.0 3.6e-87 292.2 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain ResIII PF04851.10 EWM30551.1 - 0.021 14.6 0.2 3.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit MFS_1 PF07690.11 EWM30552.1 - 6.3e-29 100.7 31.6 6.3e-29 100.7 21.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_S49 PF01343.13 EWM30553.1 - 3.8e-25 88.4 0.0 6.7e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S49 Peptidase_S49_N PF08496.5 EWM30553.1 - 4.3e-10 39.5 5.7 1.1e-09 38.2 0.0 2.5 2 0 0 2 2 2 1 Peptidase family S49 N-terminal MIP-T3 PF10243.4 EWM30553.1 - 9.8e-07 27.6 2.5 1.4e-06 27.1 1.7 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Nop14 PF04147.7 EWM30553.1 - 3.8e-06 25.1 23.5 5e-06 24.7 16.3 1.1 1 0 0 1 1 1 1 Nop14-like family Pox_Ag35 PF03286.9 EWM30553.1 - 0.0012 18.4 10.5 0.0019 17.7 7.3 1.3 1 0 0 1 1 1 1 Pox virus Ag35 surface protein Daxx PF03344.10 EWM30553.1 - 0.0019 16.8 28.4 0.0027 16.3 19.7 1.1 1 0 0 1 1 1 1 Daxx Family CDC45 PF02724.9 EWM30553.1 - 0.027 12.5 21.3 0.038 12.0 14.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Spore_coat_CotO PF14153.1 EWM30553.1 - 0.21 11.0 17.7 0.32 10.4 12.2 1.2 1 0 0 1 1 1 0 Spore coat protein CotO SDH_sah PF01972.11 EWM30553.1 - 0.26 10.0 0.1 0.47 9.1 0.0 1.3 1 0 0 1 1 1 0 Serine dehydrogenase proteinase Tim54 PF11711.3 EWM30553.1 - 0.46 9.0 9.0 0.85 8.1 6.2 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 BUD22 PF09073.5 EWM30553.1 - 0.89 8.5 29.2 1.3 7.9 20.2 1.2 1 0 0 1 1 1 0 BUD22 Ycf1 PF05758.7 EWM30553.1 - 1.2 6.7 11.8 1.6 6.3 8.2 1.1 1 0 0 1 1 1 0 Ycf1 SDA1 PF05285.7 EWM30553.1 - 1.2 8.3 32.8 2.1 7.5 22.7 1.3 1 0 0 1 1 1 0 SDA1 CENP-T PF15511.1 EWM30553.1 - 2.2 7.4 27.6 0.092 11.9 15.1 1.5 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T RR_TM4-6 PF06459.7 EWM30553.1 - 2.3 8.0 14.0 3.7 7.3 9.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2890 PF11081.3 EWM30553.1 - 2.7 8.0 21.8 7.1 6.6 15.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF1510 PF07423.6 EWM30553.1 - 3.2 7.0 29.4 5.5 6.3 20.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC27 PF09507.5 EWM30553.1 - 7.6 5.6 25.3 13 4.9 17.5 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 NOA36 PF06524.7 EWM30554.1 - 2.1 7.5 22.5 4.5 6.4 15.6 1.7 1 0 0 1 1 1 0 NOA36 protein DUF1754 PF08555.5 EWM30555.1 - 1.3e-05 25.6 10.7 1.3e-05 25.6 7.4 1.5 1 1 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) SAGA-Tad1 PF12767.2 EWM30555.1 - 0.087 12.4 3.9 0.1 12.2 2.7 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit NST1 PF13945.1 EWM30555.1 - 0.27 11.2 6.1 0.35 10.9 4.2 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator IncFII_repA PF02387.10 EWM30555.1 - 3 6.9 6.1 3.7 6.6 4.2 1.1 1 0 0 1 1 1 0 IncFII RepA protein family CDC45 PF02724.9 EWM30555.1 - 7.6 4.4 9.5 9.2 4.1 6.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Pro_isomerase PF00160.16 EWM30557.1 - 7.7e-08 32.7 0.0 1.3e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD IncA PF04156.9 EWM30557.1 - 0.034 13.7 3.1 0.05 13.1 2.1 1.2 1 0 0 1 1 1 0 IncA protein DUF3552 PF12072.3 EWM30557.1 - 0.11 11.7 9.4 0.15 11.2 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) SCFA_trans PF02667.9 EWM30557.1 - 0.12 11.1 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Short chain fatty acid transporter LmjF365940-deam PF14421.1 EWM30558.1 - 1.3e-55 187.8 0.0 4.2e-55 186.1 0.0 1.9 1 1 0 1 1 1 1 A distinct subfamily of CDD/CDA-like deaminases dCMP_cyt_deam_1 PF00383.17 EWM30558.1 - 0.0045 16.6 0.0 0.14 11.8 0.0 2.4 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region bZIP_1 PF00170.16 EWM30559.1 - 5.5e-05 23.0 4.1 0.00012 21.9 2.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EWM30559.1 - 0.026 14.3 6.6 0.059 13.1 4.6 1.5 1 0 0 1 1 1 0 Basic region leucine zipper PAS_4 PF08448.5 EWM30559.1 - 0.041 13.9 0.0 0.15 12.0 0.0 2.0 1 0 0 1 1 1 0 PAS fold DUF3414 PF11894.3 EWM30560.1 - 4e-45 153.3 1.5 1.4e-20 71.9 0.1 5.5 6 0 0 6 6 6 5 Protein of unknown function (DUF3414) DUF791 PF05631.9 EWM30562.1 - 3e-60 203.7 3.0 4e-46 157.3 0.5 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF791) MFS_1 PF07690.11 EWM30562.1 - 5.1e-22 78.0 27.2 5.1e-22 78.0 18.9 2.0 3 0 0 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EWM30562.1 - 1.3e-05 24.0 3.6 1.3e-05 24.0 2.5 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.2 EWM30562.1 - 0.00074 19.2 0.0 0.0045 16.7 0.0 2.4 1 0 0 1 1 1 1 MFS_1 like family PWWP PF00855.12 EWM30565.1 - 0.009 16.1 0.0 0.033 14.4 0.0 1.9 2 0 0 2 2 2 1 PWWP domain SOG2 PF10428.4 EWM30566.1 - 0.095 11.3 0.1 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TTL PF03133.10 EWM30567.1 - 2.9e-31 108.4 0.0 4.5e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family zf-HIT PF04438.11 EWM30568.1 - 1.2e-06 28.0 13.5 1.2e-06 28.0 9.3 1.6 2 0 0 2 2 2 1 HIT zinc finger LCM PF04072.9 EWM30569.1 - 9.7e-18 64.3 0.0 1.5e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase DUF4033 PF13225.1 EWM30570.1 - 3.3e-33 113.1 0.2 5.6e-33 112.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4033) DUF4033 PF13225.1 EWM30571.1 - 3.3e-33 113.1 0.2 5.6e-33 112.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4033) Cellulase PF00150.13 EWM30572.1 - 4.3e-06 26.1 0.0 8.9e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 EWM30572.1 - 0.015 15.7 0.7 0.043 14.2 0.1 2.1 2 0 0 2 2 2 0 Sugar-binding cellulase-like DUF1903 PF08991.5 EWM30573.1 - 7.3e-09 35.6 7.0 9.2e-09 35.3 4.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) Methyltransf_24 PF13578.1 EWM30574.1 - 4.1e-08 34.0 0.0 9.5e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Glyco_transf_34 PF05637.7 EWM30575.1 - 8.8e-21 74.4 0.2 3.1e-10 39.9 0.0 2.2 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 EWM30575.1 - 2.3e-08 33.6 0.0 3.2e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF273 Nucleotid_trans PF03407.11 EWM30575.1 - 0.00012 21.8 0.1 0.00028 20.7 0.1 1.5 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_transf_8 PF01501.15 EWM30575.1 - 0.08 12.2 4.3 1.2 8.3 2.6 2.2 1 1 0 1 1 1 0 Glycosyl transferase family 8 TatD_DNase PF01026.16 EWM30576.1 - 2.3e-48 164.6 0.0 2.6e-48 164.4 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase P5CR_dimer PF14748.1 EWM30577.1 - 2.7e-43 146.3 2.6 2.7e-43 146.3 1.8 1.7 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EWM30577.1 - 2.4e-19 69.5 1.9 5.4e-19 68.4 0.3 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 EWM30577.1 - 1.9e-05 24.4 2.9 5.9e-05 22.8 2.0 1.9 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 EWM30577.1 - 0.00026 20.8 0.2 0.00056 19.7 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase PDH PF02153.12 EWM30577.1 - 0.00042 19.2 0.4 0.00081 18.3 0.2 1.4 1 0 0 1 1 1 1 Prephenate dehydrogenase Rossmann-like PF10727.4 EWM30577.1 - 0.0038 16.9 3.8 0.0041 16.8 0.3 2.4 2 1 0 2 2 2 1 Rossmann-like domain Shikimate_DH PF01488.15 EWM30577.1 - 0.24 11.5 1.7 0.64 10.1 0.8 2.1 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase UPF0113 PF03657.8 EWM30578.1 - 2.4e-08 33.8 0.0 3.1e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) OB_NTP_bind PF07717.11 EWM30580.1 - 3.2e-28 97.8 0.0 1.4e-27 95.8 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EWM30580.1 - 4.5e-26 90.8 0.1 7.8e-26 90.0 0.0 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EWM30580.1 - 1e-10 41.2 0.0 2.5e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EWM30580.1 - 3.4e-07 29.9 0.4 1.3e-06 27.9 0.3 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EWM30580.1 - 7.9e-05 22.8 0.0 0.00027 21.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EWM30580.1 - 0.0021 17.7 0.0 0.0092 15.7 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain Flavi_DEAD PF07652.9 EWM30580.1 - 0.0042 16.8 0.1 0.0083 15.8 0.1 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain T2SE PF00437.15 EWM30580.1 - 0.0066 15.3 0.2 0.02 13.8 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein ABC_tran PF00005.22 EWM30580.1 - 0.0095 16.2 0.0 0.25 11.6 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_30 PF13604.1 EWM30580.1 - 0.014 14.9 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EWM30580.1 - 0.015 14.4 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 KaiC DUF2075 PF09848.4 EWM30580.1 - 0.015 14.2 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 EWM30580.1 - 0.027 14.3 0.0 5 6.9 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NB-ARC PF00931.17 EWM30580.1 - 0.043 12.6 0.0 0.12 11.1 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain UPF0079 PF02367.12 EWM30580.1 - 0.051 13.1 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_14 PF13173.1 EWM30580.1 - 0.17 11.7 0.0 2.1 8.2 0.0 2.4 1 1 0 1 1 1 0 AAA domain AIRC PF00731.15 EWM30581.1 - 1.4e-65 219.1 0.3 3e-65 218.1 0.2 1.6 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 EWM30581.1 - 8.1e-58 194.5 0.0 1.8e-57 193.4 0.0 1.5 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EWM30581.1 - 3.5e-13 49.6 0.0 6.5e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EWM30581.1 - 0.00026 20.4 0.0 0.00057 19.3 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.12 EWM30581.1 - 0.0015 17.8 0.0 0.0028 16.9 0.0 1.5 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.1 EWM30581.1 - 0.0016 17.2 0.0 0.33 9.6 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 EWM30581.1 - 0.0021 17.9 0.0 0.0039 17.0 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp domain 2-Hacid_dh_C PF02826.14 EWM30581.1 - 0.006 15.7 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HHH PF00633.18 EWM30582.1 - 0.038 13.6 0.3 0.12 12.1 0.1 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif Rcd1 PF04078.8 EWM30583.1 - 9.8e-128 424.5 2.0 1.1e-127 424.3 1.4 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Rcd1 PF04078.8 EWM30584.1 - 6.4e-128 425.1 2.0 7.3e-128 424.9 1.4 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Rcd1 PF04078.8 EWM30585.1 - 3.1e-123 409.7 1.2 3.5e-123 409.5 0.8 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Rcd1 PF04078.8 EWM30586.1 - 3.1e-123 409.7 1.2 3.5e-123 409.5 0.8 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Adaptin_N PF01602.15 EWM30587.1 - 1.6e-85 287.4 3.0 2.3e-85 286.9 2.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 EWM30587.1 - 6.1e-61 203.8 0.0 1.3e-60 202.8 0.0 1.5 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 EWM30587.1 - 2.3e-55 186.1 0.0 4.3e-55 185.2 0.0 1.5 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 EWM30587.1 - 5.8e-12 45.7 3.9 4.4e-06 26.8 0.0 3.9 2 1 1 3 3 3 3 HEAT repeats HEAT PF02985.17 EWM30587.1 - 6.9e-06 25.7 1.2 0.054 13.5 0.0 4.3 3 0 0 3 3 3 2 HEAT repeat Arm PF00514.18 EWM30587.1 - 6.5e-05 22.5 0.8 0.13 12.1 0.0 3.8 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EWM30587.1 - 0.00021 21.6 5.6 0.37 11.3 0.0 5.3 5 1 1 6 6 6 2 HEAT-like repeat Cnd1 PF12717.2 EWM30587.1 - 0.00088 19.1 0.7 0.02 14.7 0.1 3.1 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 FAD_binding_3 PF01494.14 EWM30588.1 - 6e-63 213.0 0.0 1.6e-62 211.6 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EWM30588.1 - 8.9e-05 21.5 0.0 0.0059 15.5 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EWM30588.1 - 0.00031 20.7 0.0 0.0033 17.3 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EWM30588.1 - 0.00081 18.3 0.0 0.0012 17.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EWM30588.1 - 0.00095 18.3 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EWM30588.1 - 0.0084 14.6 0.0 0.015 13.7 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 EWM30588.1 - 0.014 15.3 0.0 0.037 14.0 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EWM30588.1 - 0.016 14.2 0.1 0.025 13.6 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase SE PF08491.5 EWM30588.1 - 0.019 13.7 0.2 3.4 6.3 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase 3HCDH_N PF02737.13 EWM30588.1 - 0.037 13.6 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EWM30588.1 - 0.12 11.2 0.2 0.17 10.7 0.1 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.9 EWM30588.1 - 0.21 10.9 0.0 0.38 10.1 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain BolA PF01722.13 EWM30589.1 - 1.1e-18 66.8 0.0 1.5e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein MMR_HSR1 PF01926.18 EWM30590.1 - 1.1e-19 70.4 0.4 6.9e-15 55.0 0.0 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase GN3L_Grn1 PF08701.6 EWM30590.1 - 3.8e-15 55.5 16.7 3.8e-15 55.5 11.6 3.8 3 0 0 3 3 3 1 GNL3L/Grn1 putative GTPase FeoB_N PF02421.13 EWM30590.1 - 1.4e-06 27.6 0.3 3.3e-05 23.2 0.0 2.4 2 1 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EWM30590.1 - 0.00016 21.1 0.5 0.027 13.9 0.0 3.3 3 1 1 4 4 4 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EWM30590.1 - 0.00046 20.0 3.1 0.0094 15.7 1.9 3.2 2 1 0 2 2 2 1 Dynamin family DUF258 PF03193.11 EWM30590.1 - 0.0077 15.4 0.1 0.017 14.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EWM30590.1 - 0.01 16.2 0.0 0.34 11.4 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein cobW PF02492.14 EWM30590.1 - 0.042 13.2 0.8 0.38 10.1 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AIG1 PF04548.11 EWM30590.1 - 0.092 11.8 0.7 0.18 10.8 0.0 1.8 2 0 0 2 2 2 0 AIG1 family MobB PF03205.9 EWM30590.1 - 0.12 12.0 1.2 0.3 10.7 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Pox_RNA_Pol_19 PF05320.7 EWM30590.1 - 1 9.1 6.8 3.1 7.5 4.7 1.9 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Myc_N PF01056.13 EWM30590.1 - 5.3 6.1 11.4 12 4.8 7.9 1.6 1 0 0 1 1 1 0 Myc amino-terminal region Daxx PF03344.10 EWM30590.1 - 9.3 4.5 25.4 0.2 10.1 12.3 1.8 2 0 0 2 2 2 0 Daxx Family PP2C PF00481.16 EWM30591.1 - 2.1e-50 171.5 0.3 1.4e-49 168.8 0.0 2.0 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.1 EWM30591.1 - 0.00027 20.3 1.2 0.0015 17.9 0.8 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C Myb_DNA-bind_6 PF13921.1 EWM30593.1 - 3.9e-22 78.1 2.5 1.8e-14 53.5 0.5 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EWM30593.1 - 1.7e-21 76.0 0.9 1.3e-10 41.1 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF605 PF04652.11 EWM30594.1 - 0.21 10.9 9.1 0.36 10.1 6.3 1.4 1 0 0 1 1 1 0 Vta1 like Mpv17_PMP22 PF04117.7 EWM30595.1 - 2e-18 65.7 2.6 3.2e-18 65.1 1.4 1.6 1 1 0 1 1 1 1 Mpv17 / PMP22 family GTP_EFTU PF00009.22 EWM30596.1 - 8.1e-33 113.4 0.0 1.2e-32 112.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 EWM30596.1 - 1.2e-09 38.1 1.8 5.8e-07 29.5 0.1 3.2 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EWM30596.1 - 2e-06 27.7 0.0 3.9e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EWM30596.1 - 0.00046 19.4 0.1 0.0018 17.5 0.0 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EWM30596.1 - 0.0053 17.2 0.0 0.011 16.2 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein ATP_bind_1 PF03029.12 EWM30596.1 - 0.025 14.1 0.3 2.5 7.6 0.0 2.4 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein cobW PF02492.14 EWM30596.1 - 0.055 12.9 0.2 2 7.8 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 EWM30596.1 - 0.18 11.6 0.1 7 6.4 0.0 2.3 1 1 1 2 2 2 0 Dynamin family PduV-EutP PF10662.4 EWM30596.1 - 0.24 10.8 0.1 2.8 7.4 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Beach PF02138.13 EWM30597.1 - 2.9e-96 322.0 0.0 3.5e-96 321.7 0.0 1.1 1 0 0 1 1 1 1 Beige/BEACH domain Branch PF02485.16 EWM30599.1 - 1.5e-17 63.5 0.0 2.1e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme DUF4117 PF13491.1 EWM30602.1 - 0.0062 15.9 2.8 0.02 14.3 1.9 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4117) DUF998 PF06197.8 EWM30602.1 - 4.4 6.5 20.2 2.5 7.3 5.8 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF998) DUF4117 PF13491.1 EWM30603.1 - 0.0047 16.3 2.0 0.014 14.8 1.4 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4117) GRP PF07172.6 EWM30603.1 - 2.1 8.8 8.7 2.1e+02 2.4 6.0 2.5 1 1 0 1 1 1 0 Glycine rich protein family Myb_DNA-binding PF00249.26 EWM30605.1 - 2.5e-25 88.2 8.0 2.1e-12 46.8 0.2 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EWM30605.1 - 3.4e-09 36.6 16.4 4.2e-06 26.7 1.8 2.5 3 0 0 3 3 3 2 Myb-like DNA-binding domain Neisseria_PilC PF05567.6 EWM30605.1 - 0.00098 18.2 0.0 0.0022 17.1 0.0 1.5 2 0 0 2 2 2 1 Neisseria PilC beta-propeller domain Annexin PF00191.15 EWM30605.1 - 0.033 14.1 0.3 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 Annexin PABP PF00658.13 EWM30606.1 - 5.5e-29 99.6 0.4 5.5e-29 99.6 0.3 1.8 2 1 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_1 PF00076.17 EWM30606.1 - 3.7e-08 32.8 0.1 9.9e-08 31.5 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM30606.1 - 4.9e-07 29.4 0.0 9.9e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM30606.1 - 7.2e-06 25.8 0.0 1.7e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.13 EWM30609.1 - 0.015 15.2 15.7 0.033 14.0 10.9 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0029 PF01205.14 EWM30610.1 - 8.4e-34 115.5 0.0 1.3e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 DUF1949 PF09186.6 EWM30610.1 - 0.0056 16.2 0.2 0.011 15.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1949) EFG_C PF00679.19 EWM30610.1 - 0.067 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Elongation factor G C-terminus SAC3_GANP PF03399.11 EWM30611.1 - 1.1e-48 165.4 0.2 1.9e-48 164.7 0.2 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EWM30611.1 - 0.013 15.3 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 SpoU_methylase PF00588.14 EWM30614.1 - 3.7e-18 65.7 0.0 1.2e-17 64.0 0.0 1.7 1 1 0 1 1 1 1 SpoU rRNA Methylase family Pkinase PF00069.20 EWM30615.1 - 3.2e-68 229.7 0.0 3.8e-68 229.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM30615.1 - 2.3e-36 125.2 0.0 3e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EWM30615.1 - 0.00051 19.1 0.0 0.00092 18.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EWM30615.1 - 0.0014 17.6 0.0 0.0027 16.7 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EWM30615.1 - 0.0075 16.0 0.0 0.028 14.1 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family RRM_1 PF00076.17 EWM30616.1 - 1.5e-48 162.2 0.0 1.5e-20 72.6 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EWM30616.1 - 1.2e-32 111.6 0.0 2.2e-13 49.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EWM30616.1 - 2.8e-20 71.9 0.1 3.2e-08 33.2 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EWM30616.1 - 0.017 14.8 0.1 0.28 10.9 0.0 2.7 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif YqzE PF14038.1 EWM30616.1 - 0.041 13.6 0.6 0.11 12.2 0.4 1.7 1 0 0 1 1 1 0 YqzE-like protein Fibrillarin PF01269.12 EWM30617.1 - 2.8e-98 327.4 0.0 3.4e-98 327.1 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EWM30617.1 - 1.5e-07 31.2 0.0 1.8e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 EWM30617.1 - 0.012 15.1 0.1 0.026 14.0 0.0 1.7 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF1214 PF06742.6 EWM30618.1 - 3.1e-20 72.5 0.1 4.1e-20 72.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1214) Pyridox_oxase_2 PF12766.2 EWM30619.1 - 3.6e-25 88.1 0.0 2.1e-24 85.7 0.0 2.0 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.15 EWM30619.1 - 0.0037 17.2 0.0 0.0092 15.9 0.0 1.7 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Thioredoxin PF00085.15 EWM30622.1 - 9.3e-25 86.3 0.0 1.4e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EWM30622.1 - 1.5e-05 25.1 0.0 0.00043 20.4 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EWM30622.1 - 5.5e-05 23.1 0.0 9.7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.1 EWM30622.1 - 0.001 19.1 0.0 0.0097 16.0 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EWM30622.1 - 0.0094 15.5 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.1 EWM30622.1 - 0.038 13.7 0.0 3.5 7.3 0.0 2.7 2 1 1 3 3 3 0 Thioredoxin-like domain HTH_6 PF01418.12 EWM30622.1 - 0.044 13.5 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family TraF PF13728.1 EWM30622.1 - 0.17 11.3 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein SH2 PF00017.19 EWM30623.1 - 4e-09 36.1 0.0 8.3e-09 35.1 0.0 1.5 1 1 0 1 1 1 1 SH2 domain Claudin_2 PF13903.1 EWM30627.1 - 0.16 11.6 8.2 0.55 9.9 4.8 2.1 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF2079 PF09852.4 EWM30627.1 - 0.28 9.8 2.8 0.4 9.3 1.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) DUF4131 PF13567.1 EWM30627.1 - 0.31 10.4 2.5 0.63 9.4 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) YesK PF14150.1 EWM30627.1 - 0.7 10.0 5.5 0.088 12.9 0.9 1.7 2 0 0 2 2 2 0 YesK-like protein YesK PF14150.1 EWM30628.1 - 0.03 14.3 0.9 0.057 13.5 0.6 1.4 1 0 0 1 1 1 0 YesK-like protein Claudin_2 PF13903.1 EWM30628.1 - 0.072 12.7 2.6 0.067 12.8 1.1 1.5 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Kinesin PF00225.18 EWM30629.1 - 6e-17 61.3 0.0 9.7e-17 60.6 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain YEATS PF03366.11 EWM30630.1 - 0.032 13.9 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 YEATS family Pkinase PF00069.20 EWM30631.1 - 1.9e-64 217.3 0.0 2.5e-64 216.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EWM30631.1 - 3.8e-44 150.7 0.0 5e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EWM30631.1 - 1.6e-05 24.0 0.0 2.4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EWM30631.1 - 0.0008 18.5 0.5 0.0012 17.9 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ion_trans PF00520.26 EWM30632.1 - 2.5e-10 39.9 11.1 3.5e-10 39.4 7.7 1.2 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.7 EWM30632.1 - 1.2e-06 27.2 7.8 1.2e-06 27.2 5.4 2.0 1 1 1 2 2 2 1 Polycystin cation channel DUF1978 PF09321.5 EWM30632.1 - 0.047 13.1 2.4 0.081 12.3 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) AOX PF01786.12 EWM30635.1 - 6.3e-82 273.9 0.6 7.9e-82 273.6 0.4 1.1 1 0 0 1 1 1 1 Alternative oxidase RasGAP PF00616.14 EWM30635.1 - 0.092 12.3 0.1 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase DUF563 PF04577.9 EWM30639.1 - 1.4e-15 57.8 0.0 1.7e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DUF359 PF04019.7 EWM30639.1 - 0.036 13.4 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF359) TRM13 PF05206.9 EWM30639.1 - 0.13 11.4 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase TRM13 Glyco_hydro_38C PF07748.8 EWM30644.1 - 0.013 14.3 0.1 0.017 13.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal domain Med24_N PF11277.3 EWM30645.1 - 0.13 9.7 1.4 0.15 9.5 1.0 1.0 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal SSP160 PF06933.6 EWM30645.1 - 2.5 5.9 8.2 3.3 5.5 5.7 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Glyco_hydro_38 PF01074.17 EWM30646.1 - 0.02 14.1 0.0 0.026 13.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 N-terminal domain DER1 PF04511.10 EWM30647.1 - 2.7e-40 137.9 5.3 3.7e-40 137.5 3.7 1.2 1 0 0 1 1 1 1 Der1-like family Ycf1 PF05758.7 EWM30647.1 - 0.00064 17.5 1.9 0.00076 17.3 1.3 1.1 1 0 0 1 1 1 1 Ycf1 Nop14 PF04147.7 EWM30647.1 - 0.0015 16.5 18.7 0.002 16.1 13.0 1.1 1 0 0 1 1 1 1 Nop14-like family RNA_pol_3_Rpc31 PF11705.3 EWM30647.1 - 0.0032 17.4 21.3 0.0044 16.9 14.8 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Tim54 PF11711.3 EWM30647.1 - 0.0052 15.4 1.7 0.0068 15.0 1.2 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Spore_coat_CotO PF14153.1 EWM30647.1 - 0.027 13.8 10.6 0.047 13.1 7.4 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Daxx PF03344.10 EWM30647.1 - 0.066 11.6 21.8 0.088 11.2 15.1 1.1 1 0 0 1 1 1 0 Daxx Family Zip PF02535.17 EWM30647.1 - 0.069 12.1 0.8 0.13 11.2 0.6 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Bravo_FIGEY PF13882.1 EWM30647.1 - 0.077 13.9 16.5 0.11 13.3 11.4 1.2 1 0 0 1 1 1 0 Bravo-like intracellular region CDC45 PF02724.9 EWM30647.1 - 0.086 10.8 16.7 0.12 10.3 11.6 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.5 EWM30647.1 - 0.2 10.7 17.0 0.26 10.3 11.8 1.1 1 0 0 1 1 1 0 BUD22 Paf1 PF03985.8 EWM30647.1 - 0.2 10.3 18.5 0.26 9.9 12.8 1.1 1 0 0 1 1 1 0 Paf1 Hid1 PF12722.2 EWM30647.1 - 0.23 9.1 3.1 0.29 8.7 2.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DDHD PF02862.12 EWM30647.1 - 0.24 11.1 2.7 0.37 10.5 1.9 1.2 1 0 0 1 1 1 0 DDHD domain Adeno_terminal PF02459.10 EWM30647.1 - 0.26 9.4 4.0 0.35 8.9 2.8 1.3 1 0 0 1 1 1 0 Adenoviral DNA terminal protein DUF1510 PF07423.6 EWM30647.1 - 0.28 10.5 18.4 0.4 10.0 12.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) BTV_NS2 PF04514.7 EWM30647.1 - 0.38 9.5 10.9 0.53 9.1 7.6 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 SAPS PF04499.10 EWM30647.1 - 0.43 9.1 9.6 0.6 8.6 6.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Radial_spoke PF04712.7 EWM30647.1 - 0.44 9.2 12.7 0.61 8.7 8.8 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein eIF-3c_N PF05470.7 EWM30647.1 - 0.5 8.3 8.7 0.67 7.9 6.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Tom22 PF04281.8 EWM30647.1 - 0.57 9.7 12.8 1.3 8.5 8.9 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 TRAP_alpha PF03896.11 EWM30647.1 - 0.7 8.8 15.7 1 8.2 10.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Prog_receptor PF02161.10 EWM30647.1 - 0.82 8.4 8.3 1.1 7.9 5.8 1.1 1 0 0 1 1 1 0 Progesterone receptor PBP_sp32 PF07222.7 EWM30647.1 - 1 8.4 12.3 1.6 7.8 8.5 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Astro_capsid PF03115.9 EWM30647.1 - 1.4 7.1 4.1 1.7 6.8 2.8 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Sigma70_ner PF04546.8 EWM30647.1 - 3.3 7.2 18.6 5.2 6.6 12.9 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region AIF_C PF14721.1 EWM30647.1 - 4 7.6 7.5 6.8 6.9 5.2 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term NOA36 PF06524.7 EWM30647.1 - 4.3 6.5 14.2 6 6.0 9.9 1.1 1 0 0 1 1 1 0 NOA36 protein DUF740 PF05340.7 EWM30647.1 - 4.8 5.4 11.7 6.2 5.0 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Pox_Ag35 PF03286.9 EWM30647.1 - 9.5 5.6 17.0 14 5.1 11.8 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SMN PF06003.7 EWM30648.1 - 4.2e-06 26.0 0.0 5.3e-06 25.7 0.0 1.0 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) DUF4110 PF13422.1 EWM30649.1 - 2.4e-05 24.0 0.2 2.4e-05 24.0 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.1 EWM30650.1 - 1.7e-35 120.3 9.2 2.1e-09 37.2 0.0 7.4 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.1 EWM30650.1 - 1.1e-33 114.7 5.9 1.3e-07 31.2 0.0 7.2 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.1 EWM30650.1 - 1.8e-29 100.6 4.9 1.4e-10 40.8 0.0 6.3 4 1 2 6 6 6 5 Kelch motif Kelch_5 PF13854.1 EWM30650.1 - 4.5e-28 96.7 3.8 1.1e-05 25.2 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.20 EWM30650.1 - 5.5e-20 70.6 5.4 4.7e-06 26.0 0.2 6.7 6 1 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 EWM30650.1 - 2.8e-10 39.5 11.9 0.0071 16.0 0.5 6.4 7 1 0 7 7 7 3 Kelch motif FHA PF00498.21 EWM30652.1 - 1.8e-10 40.7 0.0 3.8e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain IncA PF04156.9 EWM30652.1 - 0.061 12.9 32.6 0.26 10.8 12.7 3.0 1 1 1 2 2 2 0 IncA protein ATG16 PF08614.6 EWM30652.1 - 0.11 12.3 29.5 3.9 7.2 3.8 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.4 EWM30652.1 - 0.29 10.9 34.9 0.1 12.4 1.5 3.6 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 EWM30652.1 - 0.69 8.8 26.3 0.21 10.5 3.0 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 AAA_13 PF13166.1 EWM30652.1 - 2.4 6.5 12.5 3.9 5.8 8.7 1.3 1 0 0 1 1 1 0 AAA domain Reo_sigmaC PF04582.7 EWM30652.1 - 2.4 7.2 6.3 3.2 6.8 1.2 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein CorA PF01544.13 EWM30652.1 - 3.8 6.4 8.4 5.7 5.8 5.1 1.8 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Bacillus_HBL PF05791.6 EWM30652.1 - 6.1 6.1 7.8 1.2 8.5 1.4 2.2 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) PCIF1_WW PF12237.3 EWM30653.1 - 1.1e-32 112.7 0.1 1.9e-30 105.4 0.1 2.2 2 0 0 2 2 2 2 Phosphorylated CTD interacting factor 1 WW domain MRP-63 PF14978.1 EWM30653.1 - 0.16 12.4 2.3 0.4 11.1 0.9 2.0 2 0 0 2 2 2 0 Mitochondrial ribosome protein 63 PCIF1_WW PF12237.3 EWM30654.1 - 4.9e-29 100.8 0.0 9.4e-27 93.4 0.1 2.2 2 0 0 2 2 2 2 Phosphorylated CTD interacting factor 1 WW domain MRP-63 PF14978.1 EWM30654.1 - 0.12 12.8 2.4 0.31 11.5 0.9 2.1 2 0 0 2 2 2 0 Mitochondrial ribosome protein 63 Brevenin PF03032.10 EWM30654.1 - 9 6.2 8.4 19 5.1 5.8 1.6 1 0 0 1 1 1 0 Brevenin/esculentin/gaegurin/rugosin family AzlD PF05437.7 EWM30656.1 - 0.033 14.1 0.1 0.042 13.7 0.1 1.3 1 0 0 1 1 1 0 Branched-chain amino acid transport protein (AzlD) Aminotran_3 PF00202.16 EWM30657.1 - 1.2e-49 169.0 0.0 1.1e-48 165.8 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-III PTPLA PF04387.9 EWM30658.1 - 1.2e-37 128.9 2.9 1.6e-37 128.4 2.0 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Hpre_diP_synt_I PF07456.6 EWM30658.1 - 0.04 13.7 1.1 0.071 12.9 0.8 1.4 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase component I Indigoidine_A PF04227.7 EWM30659.1 - 9.5e-119 395.9 2.1 1.2e-118 395.6 1.5 1.1 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 EWM30659.1 - 4.3e-07 29.3 0.0 1.1e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Peptidase_M1 PF01433.15 EWM30660.1 - 9.5e-33 113.8 0.0 1.4e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 HEAT_2 PF13646.1 EWM30660.1 - 3.7e-09 36.7 3.8 5.5e-05 23.3 0.1 3.1 2 1 1 3 3 3 2 HEAT repeats Peptidase_MA_2 PF13485.1 EWM30660.1 - 0.0068 16.4 0.2 0.032 14.2 0.3 2.0 2 0 0 2 2 2 1 Peptidase MA superfamily HEAT_EZ PF13513.1 EWM30660.1 - 0.079 13.4 1.6 0.46 11.0 0.1 2.7 2 0 0 2 2 2 0 HEAT-like repeat Arm PF00514.18 EWM30660.1 - 0.083 12.7 0.1 0.59 10.0 0.1 2.3 1 1 1 2 2 2 0 Armadillo/beta-catenin-like repeat Peptidase_M1 PF01433.15 EWM30661.1 - 1.1e-32 113.5 0.0 1.7e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 HEAT_2 PF13646.1 EWM30661.1 - 4.2e-09 36.5 3.8 5.7e-05 23.3 0.1 3.1 2 1 1 3 3 3 2 HEAT repeats Peptidase_MA_2 PF13485.1 EWM30661.1 - 0.007 16.4 0.2 0.033 14.2 0.3 2.0 2 0 0 2 2 2 1 Peptidase MA superfamily HEAT_EZ PF13513.1 EWM30661.1 - 0.085 13.3 1.6 0.48 10.9 0.1 2.7 2 0 0 2 2 2 0 HEAT-like repeat Arm PF00514.18 EWM30661.1 - 0.087 12.6 0.1 0.6 10.0 0.1 2.3 1 1 1 2 2 2 0 Armadillo/beta-catenin-like repeat Lipase_3 PF01764.20 EWM30663.1 - 1.2e-28 99.4 0.0 2e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) C2 PF00168.25 EWM30663.1 - 2.4e-09 36.9 0.0 5.1e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 C2 domain Acetyltransf_9 PF13527.1 EWM30664.1 - 5.1e-09 36.0 0.0 2.7e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EWM30664.1 - 6.1e-07 29.5 0.0 1.7e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EWM30664.1 - 1.6e-06 28.0 0.0 4.6e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EWM30664.1 - 0.0019 18.2 0.0 0.01 15.9 0.0 2.4 3 1 1 4 4 4 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EWM30664.1 - 0.0026 17.9 0.0 0.013 15.6 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EWM30664.1 - 0.013 15.4 0.1 0.033 14.0 0.1 1.7 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.5 EWM30664.1 - 0.042 13.5 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein Zn_clus PF00172.13 EWM30665.1 - 8.5e-06 25.5 4.4 2e-05 24.4 3.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Claudin_3 PF06653.6 EWM30666.1 - 0.22 11.2 11.6 8.2 6.1 8.0 2.3 1 1 0 1 1 1 0 Tight junction protein, Claudin-like DUF443 PF04276.7 EWM30666.1 - 1.6 8.1 4.0 0.96 8.8 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF443) CDC45 PF02724.9 EWM30667.1 - 0.019 13.0 0.5 0.025 12.6 0.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Exo_endo_phos PF03372.18 EWM30668.1 - 1.1e-11 45.1 0.1 1.8e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family 2OG-FeII_Oxy_3 PF13640.1 EWM30669.1 - 4.5e-17 62.3 0.0 2e-15 57.0 0.0 2.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EWM30669.1 - 1.7e-08 33.9 0.0 3.4e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.1 EWM30669.1 - 0.15 12.3 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Aminotran_3 PF00202.16 EWM30671.1 - 3e-05 23.0 0.0 3.8e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III TadE PF07811.7 EWM30671.1 - 0.48 10.3 3.9 0.83 9.5 2.7 1.4 1 0 0 1 1 1 0 TadE-like protein BTB PF00651.26 EWM30672.1 - 2.8e-18 65.9 0.2 5.4e-15 55.3 0.0 3.2 2 1 1 3 3 3 2 BTB/POZ domain Kelch_5 PF13854.1 EWM30672.1 - 1.1e-08 34.8 0.0 0.011 15.7 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 EWM30672.1 - 1.3e-08 34.4 1.3 0.33 10.7 0.0 6.6 6 1 0 6 6 6 2 Galactose oxidase, central domain Kelch_2 PF07646.10 EWM30672.1 - 3.8e-05 23.2 0.4 4.9 7.0 0.0 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 EWM30672.1 - 0.0003 20.8 12.1 0.11 12.6 0.0 6.3 7 0 0 7 7 7 1 Galactose oxidase, central domain WD40 PF00400.27 EWM30672.1 - 0.00087 19.0 3.3 0.0018 18.0 0.3 3.0 3 0 0 3 3 3 1 WD domain, G-beta repeat YkyA PF10368.4 EWM30673.1 - 3e-05 23.4 2.9 0.034 13.4 0.2 2.3 1 1 1 2 2 2 2 Putative cell-wall binding lipoprotein M16C_assoc PF08367.6 EWM30673.1 - 0.071 11.9 0.2 0.99 8.2 0.0 2.2 2 0 0 2 2 2 0 Peptidase M16C associated